LOCUS       DAFLVO010000001       100707 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.001, whole genome shotgun sequence.
ACCESSION   DAFLVO010000001 DAFLVO010000000
VERSION     DAFLVO010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 100707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 100707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..100707
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.001"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(553..2166)
                     /locus_tag="L1U99_000001"
     CDS             complement(553..2166)
                     /locus_tag="L1U99_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBN1210582.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2307..3215)
                     /locus_tag="L1U99_000002"
     CDS             complement(2307..3215)
                     /locus_tag="L1U99_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1210583.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            3398..4522
                     /locus_tag="L1U99_000003"
     CDS             3398..4522
                     /locus_tag="L1U99_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBN1210584.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            4749..5666
                     /locus_tag="L1U99_000004"
     CDS             4749..5666
                     /locus_tag="L1U99_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1210585.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            5659..6492
                     /locus_tag="L1U99_000005"
     CDS             5659..6492
                     /locus_tag="L1U99_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1210586.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            6575..7693
                     /locus_tag="L1U99_000006"
     CDS             6575..7693
                     /locus_tag="L1U99_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBN1210587.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            7687..9585
                     /locus_tag="L1U99_000007"
     CDS             7687..9585
                     /locus_tag="L1U99_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HBN1210588.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            9579..10802
                     /locus_tag="L1U99_000008"
     CDS             9579..10802
                     /locus_tag="L1U99_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBN1210589.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(10888..12822)
                     /locus_tag="L1U99_000009"
     CDS             complement(10888..12822)
                     /locus_tag="L1U99_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBN1210590.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            13048..13704
                     /locus_tag="L1U99_000010"
     CDS             13048..13704
                     /locus_tag="L1U99_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBN1210591.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(13778..14131)
                     /locus_tag="L1U99_000011"
     CDS             complement(13778..14131)
                     /locus_tag="L1U99_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBN1210592.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            14323..15252
                     /locus_tag="L1U99_000012"
     CDS             14323..15252
                     /locus_tag="L1U99_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBN1210593.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            15263..16099
                     /locus_tag="L1U99_000013"
     CDS             15263..16099
                     /locus_tag="L1U99_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HBN1210594.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            16347..17123
                     /locus_tag="L1U99_000014"
     CDS             16347..17123
                     /locus_tag="L1U99_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1210595.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            17299..18042
                     /locus_tag="L1U99_000015"
     CDS             17299..18042
                     /locus_tag="L1U99_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1210596.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            18035..19615
                     /locus_tag="L1U99_000016"
     CDS             18035..19615
                     /locus_tag="L1U99_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HBN1210597.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(19866..20345)
                     /locus_tag="L1U99_000017"
     CDS             complement(19866..20345)
                     /locus_tag="L1U99_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBN1210598.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(20361..21113)
                     /locus_tag="L1U99_000018"
     CDS             complement(20361..21113)
                     /locus_tag="L1U99_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBN1210599.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            21230..21300
                     /locus_tag="L1U99_000019"
     tRNA            21230..21300
                     /locus_tag="L1U99_000019"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21262..21264,aa:Gly,seq:ccc)
     gene            21661..22386
                     /locus_tag="L1U99_000020"
     CDS             21661..22386
                     /locus_tag="L1U99_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBN1210600.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            22641..22907
                     /locus_tag="L1U99_000021"
     CDS             22641..22907
                     /locus_tag="L1U99_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBN1210601.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPSYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            22904..23335
                     /gene="ruvX"
                     /locus_tag="L1U99_000022"
     CDS             22904..23335
                     /gene="ruvX"
                     /locus_tag="L1U99_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBN1210602.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            23360..23665
                     /locus_tag="L1U99_000023"
     CDS             23360..23665
                     /locus_tag="L1U99_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBN1210603.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(23746..24891)
                     /locus_tag="L1U99_000024"
     CDS             complement(23746..24891)
                     /locus_tag="L1U99_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1210604.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(24952..25599)
                     /locus_tag="L1U99_000025"
     CDS             complement(24952..25599)
                     /locus_tag="L1U99_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1210605.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            25793..26086
                     /locus_tag="L1U99_000026"
     CDS             25793..26086
                     /locus_tag="L1U99_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210606.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            26130..26441
                     /locus_tag="L1U99_000027"
     CDS             26130..26441
                     /locus_tag="L1U99_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210607.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            26438..27062
                     /locus_tag="L1U99_000028"
                     /pseudo
     CDS             26438..27062
                     /locus_tag="L1U99_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            27203..27361
                     /locus_tag="L1U99_000029"
     CDS             27203..27361
                     /locus_tag="L1U99_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210608.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            27362..27724
                     /locus_tag="L1U99_000030"
     CDS             27362..27724
                     /locus_tag="L1U99_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210609.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            27761..28609
                     /locus_tag="L1U99_000031"
     CDS             27761..28609
                     /locus_tag="L1U99_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HBN1210610.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            28599..30074
                     /locus_tag="L1U99_000032"
     CDS             28599..30074
                     /locus_tag="L1U99_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HBN1210611.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            30340..30747
                     /locus_tag="L1U99_000033"
     CDS             30340..30747
                     /locus_tag="L1U99_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HBN1210612.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            30750..30965
                     /locus_tag="L1U99_000034"
     CDS             30750..30965
                     /locus_tag="L1U99_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210613.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            30969..31349
                     /locus_tag="L1U99_000035"
     CDS             30969..31349
                     /locus_tag="L1U99_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBN1210614.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            31483..31638
                     /locus_tag="L1U99_000036"
     CDS             31483..31638
                     /locus_tag="L1U99_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HBN1210615.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            31707..32180
                     /locus_tag="L1U99_000037"
     CDS             31707..32180
                     /locus_tag="L1U99_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HBN1210616.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            32177..33871
                     /locus_tag="L1U99_000038"
     CDS             32177..33871
                     /locus_tag="L1U99_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBN1210617.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            33837..34022
                     /locus_tag="L1U99_000039"
     CDS             33837..34022
                     /locus_tag="L1U99_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210618.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            34026..35201
                     /locus_tag="L1U99_000040"
     CDS             34026..35201
                     /locus_tag="L1U99_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBN1210619.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            35194..36717
                     /locus_tag="L1U99_000041"
     CDS             35194..36717
                     /locus_tag="L1U99_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBN1210620.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            36773..37057
                     /locus_tag="L1U99_000042"
     CDS             36773..37057
                     /locus_tag="L1U99_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBN1210621.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            37044..37379
                     /locus_tag="L1U99_000043"
     CDS             37044..37379
                     /locus_tag="L1U99_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBN1210622.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            37674..38300
                     /locus_tag="L1U99_000044"
     CDS             37674..38300
                     /locus_tag="L1U99_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210623.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            39042..39878
                     /locus_tag="L1U99_000045"
     CDS             39042..39878
                     /locus_tag="L1U99_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBN1210624.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLINLYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            39942..40373
                     /locus_tag="L1U99_000046"
     CDS             39942..40373
                     /locus_tag="L1U99_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1210625.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(40435..41757)
                     /locus_tag="L1U99_000047"
     CDS             complement(40435..41757)
                     /locus_tag="L1U99_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBN1210626.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(41911..43551)
                     /locus_tag="L1U99_000048"
     CDS             complement(41911..43551)
                     /locus_tag="L1U99_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HBN1210627.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            43884..44354
                     /locus_tag="L1U99_000049"
     CDS             43884..44354
                     /locus_tag="L1U99_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HBN1210628.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            44576..45679
                     /locus_tag="L1U99_000050"
     CDS             44576..45679
                     /locus_tag="L1U99_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBN1210629.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLKDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            45963..46643
                     /locus_tag="L1U99_000051"
     CDS             45963..46643
                     /locus_tag="L1U99_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBN1210630.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            46733..47767
                     /locus_tag="L1U99_000052"
     CDS             46733..47767
                     /locus_tag="L1U99_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBN1210631.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            47781..48116
                     /locus_tag="L1U99_000053"
     CDS             47781..48116
                     /locus_tag="L1U99_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210632.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            48100..50580
                     /locus_tag="L1U99_000054"
     CDS             48100..50580
                     /locus_tag="L1U99_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210633.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWKLTAGPTS"
     gene            50636..52195
                     /locus_tag="L1U99_000055"
     CDS             50636..52195
                     /locus_tag="L1U99_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1210634.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            52192..53556
                     /locus_tag="L1U99_000056"
     CDS             52192..53556
                     /locus_tag="L1U99_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBN1210635.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            53727..54797
                     /locus_tag="L1U99_000057"
     CDS             53727..54797
                     /locus_tag="L1U99_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1210636.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            54812..55480
                     /locus_tag="L1U99_000058"
     CDS             54812..55480
                     /locus_tag="L1U99_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1210637.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            55500..56078
                     /locus_tag="L1U99_000059"
     CDS             55500..56078
                     /locus_tag="L1U99_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1210638.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            56479..57390
                     /locus_tag="L1U99_000060"
     CDS             56479..57390
                     /locus_tag="L1U99_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1210639.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(57478..58395)
                     /locus_tag="L1U99_000061"
     CDS             complement(57478..58395)
                     /locus_tag="L1U99_000061"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HBN1210640.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            58597..59034
                     /gene="zapA"
                     /locus_tag="L1U99_000062"
     CDS             58597..59034
                     /gene="zapA"
                     /locus_tag="L1U99_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBN1210641.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            59093..59641
                     /locus_tag="L1U99_000063"
     CDS             59093..59641
                     /locus_tag="L1U99_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HBN1210642.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            59756..62116
                     /locus_tag="L1U99_000064"
     CDS             59756..62116
                     /locus_tag="L1U99_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBN1210643.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEEQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLYDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            62203..62517
                     /gene="trxA"
                     /locus_tag="L1U99_000065"
     CDS             62203..62517
                     /gene="trxA"
                     /locus_tag="L1U99_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBN1210644.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            62699..64477
                     /gene="uvrC"
                     /locus_tag="L1U99_000066"
     CDS             62699..64477
                     /gene="uvrC"
                     /locus_tag="L1U99_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBN1210645.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            64622..65521
                     /locus_tag="L1U99_000067"
     CDS             64622..65521
                     /locus_tag="L1U99_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1210646.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            65514..66776
                     /locus_tag="L1U99_000068"
     CDS             65514..66776
                     /locus_tag="L1U99_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1210647.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            66937..68835
                     /locus_tag="L1U99_000069"
     CDS             66937..68835
                     /locus_tag="L1U99_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HBN1210648.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(69165..69884)
                     /locus_tag="L1U99_000070"
     CDS             complement(69165..69884)
                     /locus_tag="L1U99_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBN1210649.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            70221..70553
                     /locus_tag="L1U99_000071"
     CDS             70221..70553
                     /locus_tag="L1U99_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210650.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            70540..72543
                     /locus_tag="L1U99_000072"
     CDS             70540..72543
                     /locus_tag="L1U99_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBN1210651.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            72562..73032
                     /locus_tag="L1U99_000073"
     CDS             72562..73032
                     /locus_tag="L1U99_000073"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBN1210652.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            73053..73637
                     /locus_tag="L1U99_000074"
     CDS             73053..73637
                     /locus_tag="L1U99_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HBN1210653.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            73652..74638
                     /locus_tag="L1U99_000075"
     CDS             73652..74638
                     /locus_tag="L1U99_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HBN1210654.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            74628..74939
                     /locus_tag="L1U99_000076"
     CDS             74628..74939
                     /locus_tag="L1U99_000076"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBN1210655.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            74961..76742
                     /locus_tag="L1U99_000077"
     CDS             74961..76742
                     /locus_tag="L1U99_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBN1210656.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            76735..78111
                     /locus_tag="L1U99_000078"
     CDS             76735..78111
                     /locus_tag="L1U99_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBN1210657.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            78118..78753
                     /locus_tag="L1U99_000079"
     CDS             78118..78753
                     /locus_tag="L1U99_000079"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBN1210658.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            78783..80138
                     /locus_tag="L1U99_000080"
     CDS             78783..80138
                     /locus_tag="L1U99_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBN1210659.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(80330..81724)
                     /locus_tag="L1U99_000081"
     CDS             complement(80330..81724)
                     /locus_tag="L1U99_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBN1210660.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRTQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            81816..82787
                     /locus_tag="L1U99_000082"
     CDS             81816..82787
                     /locus_tag="L1U99_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBN1210661.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            82784..83566
                     /locus_tag="L1U99_000083"
     CDS             82784..83566
                     /locus_tag="L1U99_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBN1210662.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(83735..84106)
                     /locus_tag="L1U99_000084"
     CDS             complement(83735..84106)
                     /locus_tag="L1U99_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1210663.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            84240..84683
                     /locus_tag="L1U99_000085"
     CDS             84240..84683
                     /locus_tag="L1U99_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBN1210664.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(84726..85535)
                     /gene="yidA"
                     /locus_tag="L1U99_000086"
     CDS             complement(84726..85535)
                     /gene="yidA"
                     /locus_tag="L1U99_000086"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBN1210665.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(85554..86921)
                     /locus_tag="L1U99_000087"
     CDS             complement(85554..86921)
                     /locus_tag="L1U99_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBN1210666.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(86905..87735)
                     /locus_tag="L1U99_000088"
     CDS             complement(86905..87735)
                     /locus_tag="L1U99_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBN1210667.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            87898..88335
                     /locus_tag="L1U99_000089"
     CDS             87898..88335
                     /locus_tag="L1U99_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBN1210668.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            88411..89031
                     /locus_tag="L1U99_000090"
     CDS             88411..89031
                     /locus_tag="L1U99_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HBN1210669.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            89220..89726
                     /locus_tag="L1U99_000091"
     CDS             89220..89726
                     /locus_tag="L1U99_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HBN1210670.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            89743..90642
                     /locus_tag="L1U99_000092"
     CDS             89743..90642
                     /locus_tag="L1U99_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBN1210671.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            90729..91613
                     /locus_tag="L1U99_000093"
     CDS             90729..91613
                     /locus_tag="L1U99_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBN1210672.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(91805..91876)
                     /locus_tag="L1U99_000094"
     tRNA            complement(91805..91876)
                     /locus_tag="L1U99_000094"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(91841..91843),aa:Arg,seq:ccg)
     gene            91936..93270
                     /gene="rpoN"
                     /locus_tag="L1U99_000095"
     CDS             91936..93270
                     /gene="rpoN"
                     /locus_tag="L1U99_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBN1210673.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            93419..94510
                     /locus_tag="L1U99_000096"
     CDS             93419..94510
                     /locus_tag="L1U99_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HBN1210674.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            94551..95552
                     /gene="gap"
                     /locus_tag="L1U99_000097"
     CDS             94551..95552
                     /gene="gap"
                     /locus_tag="L1U99_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBN1210675.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            95662..96852
                     /locus_tag="L1U99_000098"
     CDS             95662..96852
                     /locus_tag="L1U99_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBN1210676.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            96956..97711
                     /locus_tag="L1U99_000099"
     CDS             96956..97711
                     /locus_tag="L1U99_000099"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBN1210677.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            97827..99125
                     /gene="eno"
                     /locus_tag="L1U99_000100"
     CDS             97827..99125
                     /gene="eno"
                     /locus_tag="L1U99_000100"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBN1210678.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            99524..100663
                     /locus_tag="L1U99_000101"
     CDS             99524..100663
                     /locus_tag="L1U99_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HBN1210679.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT        33405 a        17205 c        20782 g        29315 t
ORIGIN      
        1 gttaaataaa taggaacaaa aaaattaaat tatttaatac acacattagg gatcattcat
       61 tgaaggatta gaagacaacg aggatggcga aaaatatgat tacaatagaa aagtcgttct
      121 aaaccaatca gttcctagta tcacacaacg caagccagtc gatttggtga gattagagga
      181 gtgaaagcaa actttattat ataagaaaaa atattcgaaa gggatgctag tttaggtact
      241 agtgctgata gattaatatg atgcctcgta atattaggcg tagttactct agagacatca
      301 ctatggacta tgatttgtct cagagtcaca acatgttttt ttatgaaaag aaacagctaa
      361 aataattaaa ttgcgcaatg tttaaacttt cttaaactat aacctaataa atgtgaagaa
      421 ataatgcaca atttcttcac atttatcttc tattctatat acataccaac caacaaccct
      481 atatactttt tcatttttac tcctcaagta aaaataactc ctagaccgcg gctacccacc
      541 gcggtcgttt ttttattctt caatcaaaat cgctttgata cccaaacctg ccaagattcg
      601 ggcagaagta taagtattca atcctcttct gaaagtaatg taaacttttt tatcttttgg
      661 gatttcattg attcgatctc gtaactcatt cattggaata ttttttgttg ccgagatact
      721 gccagaaggt gctttattag gttcacgtat atctaaaaag aacgcttctt tcaaatcgtt
      781 ttcgggtata tcacttgctt tgatcgtttc tacgatattc gtcatttgat tgattgcgac
      841 ataaccagct atattcaacg ggtcacgggt agtagaatac ggtggagagt aaggcaactc
      901 caaatcaggc aaatcaaaga ctgtcaagtt tccggtgatt gctacagaaa gttctcccat
      961 ccgtttatcg acaccttttt ctccaaatgc ttgtccacct aaaatacgac cgctatctgc
     1021 atcaaaaatc agctttagat ttaatcttgt agcttctgga tagaaatagg catggtcaaa
     1081 gggagtgata aaaacagttt tataatttgt tatgcctgat gcttttaatt catgttctgt
     1141 cattcccgca taacttgctg tatgatcaaa gatttttgcg acacctgcac caatatatcc
     1201 gcgatagcgc ataggcgtac catttaaaat atctgccagc atatgtcctt gacgattggc
     1261 cgcactggaa agcatacttt ggatcggctg accagtcact acactagtcg tttcgataat
     1321 atcgccaatc gcatagatgt ccggcagatt ggtttgtaac tggtcatcaa caatgatctg
     1381 acctgtatct gataattgta tgccggttgc tttcaccact tcattcttcg gagaaacacc
     1441 aacagcaaaa attagcatat cagcagaaag gacggagcca tctgataata ctatttctcg
     1501 acctttatca cggatctcag taactcttgt ttctaaatga acggctaatc cttctttcag
     1561 caatttgtca taaactaaat tagcaatttc tggatcataa gggaaagcga cttgtggcaa
     1621 ttgatcgatt aaagtcacgt ctaagccgcg atgcttgaaa ttctcagcta attccagacc
     1681 cataacacct gcaccaagaa tgacgacatg ttgtggattt ttttcttcaa ggaacgattt
     1741 gattcgatcc gcatccgtca cactacggag gacaaagccg ttttctgctt caaaaactcc
     1801 gggaatatcc ggataatctg gtctagcacc agaagagatg atcaacttat cgtaatctgt
     1861 ttttatttct tcatttgtgg ataggtcttt aactgttaat cgcttagtag aaggatcgat
     1921 tgctgttact tcgtgtttag taaagacatc gatgttgttt tttgttttca atatttctgg
     1981 tgtacgttcg atcagcgagt cacggtcagt gatcacacct cctaaataat aaggcaaagc
     2041 acaacttgca taagaaatat tttctccgcg ttcatagata atgatttcgt gcgcttcatt
     2101 caatcgacgg aaacgagtgg caaatgaagg accgccagct acaccgccaa tgacaacaac
     2161 tttcataaaa acatctcctt ttctacgttg atcgtactat gttatggtaa aaaacagcaa
     2221 ataattgtgc cggaaaatta ttgtttattt tgaatagaca gaaaatatag agaaataatt
     2281 tgtggataaa acctaaaaat ttttttctat tttaaggata gataatactt tgaaggggat
     2341 aaccctgtat attttttaaa agctgaagaa aaatgatgga tcgaatgaaa tcctaatata
     2401 tctgcaattt ctgtataggt taattcattt tctagcacga gacgttttgc tttttccatt
     2461 tttagttctt taaaatagct aataacactt tttccattca cttttctaaa atgttttttt
     2521 aagctggctg gactgataaa aaaaatttgg gctaattgtt caagcaaaaa attttctgaa
     2581 agatgttctt ctaaatatcg tatgattgga tcaactaatt catctgaata aagaatatgc
     2641 ttttttttag gaatgacttt ctcatttgaa ggtattgtca ataaagcaag ttcctgttga
     2701 taatgccttg gtaaggaaga caattgaatt ttttgcagac aataagtaac taataaggaa
     2761 agcaaatgaa tgctcatctg ttggcatagt atgaaaaaag aattgatttc ctgatcatag
     2821 gaaatagctg gcttactatg ttttagataa tcaattttga actgttcatt tttcagaaaa
     2881 gtaatgatag atgttatttc ttgatctata gaaaaagatt gtcccgtaat atgtgctaat
     2941 aattgctcat caaaataaaa ctggataatg ataaaagttt gtgtttcctt ttgagtagaa
     3001 aagatttgga cttcttgctg tttatcaatg aataaaaggg aaggattatc tagttctata
     3061 gatttatgtg caaattcagc atataaatta gcgctttcat ttattagtag tcgaaaatag
     3121 ggagcagcag ataaatgaag atgggtatct atggaatagg ttagtgtttt tttgacaaga
     3181 ttggaggatt ggttgtttgt taacaaaaga accactttcc tttctctttt tatataaaaa
     3241 gctttctatt tataattaat gactattata acaaaaatga aaagccaaaa cgacaagtaa
     3301 aatatttttt tatataaata tttgtgttac taattccgtt aatatacata agtgaaagcg
     3361 ttttatataa gaacttgaaa agaaagaagg gatagacatg aaaaaaagat acaaattggt
     3421 gatagctttg ctaaacatta ccctattatt cagcttaagt gcatgtggaa aaactaacga
     3481 agaagtaaca gcaaacatcg cagatccaat gataaaaaaa gccactacat tagaagtata
     3541 tgtcgcaaac ggcaaactga caaactatgt tgaaaatgct gcaaaaatct ataaccgcaa
     3601 aactggagca aatattgact taaaaattgt gaatgtagct tcgggaacag caacagtaca
     3661 aatgatcacc ccaaaattgg taacacacga agatatgccg gatattatct ccatggcaga
     3721 cacttcagca gcaggtgtgc tggaaaaatt tcaagatgct ttttatagtg ctgatgaata
     3781 tggattttat gacaaatatg gcgatcagtt ttatgatcaa aaattgaata ttttgcgtca
     3841 acaaacgagt aatgaaacga ttattccttg ggctagtgat tttaccccag cactttgtta
     3901 ttatcaacca aaaaaatttg ctgaaatagg tgtagatttt gaagaaatca gttcttggga
     3961 agaatatatc caggtggcaa aagcattaaa agaaaaaact ggtagttttg gaattgcctt
     4021 gccagaatct ggggaccaag aattgtttat caacatgcta gcccagcaga atcaatcttt
     4081 gcttgatgaa gaaggaaata tccgtctgaa tactaaagaa gcgaaacatg ctgcaaagtt
     4141 aatcaaagaa atgatcgact cagatattgt acatttctac ggtgcacaag atgctgagaa
     4201 agcatttcaa gaatctgcaa tgtttgttgc tggcggctgg tatgctacga atatgtcttt
     4261 gaattttcct gatgcatctg acaaatggcg catggctcca ctgattcctt tttcaaaaga
     4321 aaatccagga aaaggtgcag tatcaggagg atcaagtttt tatgtcccta aagatgcaaa
     4381 aaatccacaa gtggcacaac aatttcttac atttatgctg acagatgaag aatgcttagc
     4441 caacgcactg gagctgggcg tggctacatc taactcattg gcctatcaaa cagaagcagc
     4501 tgagaaaaag tttgactact aaggaggaca aaaatactat gaactattga ataaaatcaa
     4561 tgaaaataca tcaaatactg ttttaccagc cacttattca gatgctacgt cttatttgac
     4621 taccgctgca tataactatt ggcaaacagg tgattttgaa aattcatatc taaaagaagc
     4681 agaaaatttt gctcataagt acggcgtaaa attaactggt gattaaaaaa tattaggagg
     4741 acttaacgat gatgcaatct tcgttaccaa gcaagacaat aaagaacagc aagaaaaaag
     4801 caacagatac gtctcataaa aaaagtgctt atggattggt cacacctttt gttattttct
     4861 ttattgtgac gattttgatt cccatcatta tctcgtttgc ttttagtttt atgaaaattg
     4921 gctactcatt tgaatttgtt ggatttgaca attatctagc tatcttccga gatccattgt
     4981 ttattaaatc ttacacgaat gttttgatta tcatggcagg atcaattcca ataacgatgc
     5041 tattagctat ttactttgct gttttattga attcagcaca gttaaaagga aaaggatttt
     5101 ttagaactgt ctattatatt ccaaccatta catcaacggt ggctgtagct tccgtattca
     5161 tgactttttt caatccgact gggttattca atggattttt gaatgcgcta ggaattaacg
     5221 gtgtacagtg gttaacaaat cctttttgga tacgaatatc aatgatcatc acgatgattt
     5281 ggcttagtgt aggatataac actattttat ttttagctgg tcttcaaggg atttctaaag
     5341 agatatacga aagtgctgaa atagatggag catcgaaatt tcggcaattc tttttattaa
     5401 cgatccccat gctaaagcca atcattttaa tggccacagt tttagccact atcaatggct
     5461 tgggtaattt caatatccca aatatattct ttgggacttc caatggacca gaaaattcag
     5521 ctttggtcgt aggagtcaat ttatataaaa caagttttga aatggttgat tttggaaaag
     5581 cctctgctat tgcctggacg atggtgtttg tatctgttat attatcggct attcaattta
     5641 aattcggagg tgataaaaat gactaaacaa aagatacaaa gcagaatttt tacgtacgtc
     5701 attattgtgt ttggtgcctt aatatttttg atgccatatt tatatatgat tgtagcttca
     5761 acgcaaagta atcaagaaat tttaagtggc ggaatcaatt tcaagtttgg ggatatgcta
     5821 ttaaaaaact ggcaagccat catggcgaga tataattatc ccttgattat ttggaattcg
     5881 attgttattg ctgtaatcag tacagtttta gctacagcca gttctacaat ggcgggttat
     5941 gcattagcaa agtatcgttt tatggggaat aaactgttgt tcaatacagt tatgctatct
     6001 aggatggtgc ctttttttac cacattgatt cctttatttt acattatgag tcgtttagga
     6061 ttatcgaata cttatgcagg tgtgatcatc ccttcgattg ccagtacaac ttcagtgttt
     6121 atgatgcgac aatatagcag tcaatttcct acagcactga tggaggctgc cagaatcgat
     6181 ggtgccaatg agtgggtgat ttttacgaaa atcgctgtac cgattttatc acctacgatt
     6241 attactagtg gtttacttat ctttatggga agttggaatc aatatctatt tccattagtc
     6301 atgctttcag ataaagataa atatacggtt cccttaatta tcaaaaatat gacggtttct
     6361 agtacaggtg agccaattaa ttatggcgca attatgctaa ttttagcaac ttcagtgatc
     6421 ccaatggtct tgatttatgt gtgggcgcag tctaaattta aggagaatga cattggagct
     6481 gcaaataagt aaaaaaaata acgaatgtta accatctagt tcgttctagg agcaactcca
     6541 cattcataaa aattaaaaga atggcgggat atccatgaat gaacagacga aggaatggtc
     6601 aagaaaaatt ttgaatgtag cttctgaaaa gatagatgcg gaattagaca gaatggggaa
     6661 taaaattcca tatatttctt acaacggaaa atatacagac gtaataaagg acagaggaat
     6721 cgactggtgg accaatggtt tttggagtgg tattttatgg cagctctttc acaagacaaa
     6781 acgagaaaag ttcaaagagg cagcaataca acaagaacaa ttattagaat ctgccctgta
     6841 ccatttttca gacgttcatc atgatgtagg ttttttattc ttaccatcgg ctattgcaca
     6901 ttatcaacag tctcaaaaca aacatagtcg acaactaggg ttacatgcag ctacggtact
     6961 tgctggacgc tataatattt cagggaacta tttagtagca tggaatgacc ataaacctgg
     7021 ttggatgatt attgatagta tgatgaattt accattactg tattgggctt cgagggaaac
     7081 tggtgatccg aggttctcta aaattgctcg gcagcatgca gatacaacag ctaagtatct
     7141 agtgaggaaa gatggatcaa ccgggcatat cgcagaattt gatgcagaat cagggaaata
     7201 tattcggtta cttggcgggc aaggatacaa tgagaattct tgttggagca gaggaaatgc
     7261 atgggcttta tatggattcg cgttaagtta tcgttacaca aaaaatccgt actatctagc
     7321 tatagcagaa aagatagcag taaattttat tcagaaaatc gaaaaaactg gttatattcc
     7381 tctcattgat tttgctgtaa aagattcgaa tattgatacc agtgctggag tatgcgctgc
     7441 atgcggtctt ctggaattag caggatatgt ttcctctgta cgatcaaaaa tgtatcatga
     7501 agctgctatc aatatactcc aaaagacaga aaagcactat gcaaattgga atatggatga
     7561 agatgggatc attggaggcg gagcagaagc ataccataga gaactgactt ataatgtgcc
     7621 actgatctat tctgattatt tttttattga aggcttactt cgattagaac agtcggaatt
     7681 agctatttgg tagtaaaaag aggagaaaat acaatgaaac atccagtacc actattaagg
     7741 accagacagg attactttga cttatttaaa aagataaatc aaccactcca gccgttttat
     7801 cgagcaagtg gcgcacaaat tgattatata catcaagggg taggatatgg aaataaaatt
     7861 gcaggaatgg aaggattctc tcgggtttta tggggagcgg ggcccgcaat tgaccaatta
     7921 gatgaacgat ggttgaaatt aattctatca ggaataaaag ctggaacaga tccttcccat
     7981 cccgattatt ggggagaaat acatgaaaga gaccagcgta tggtagaaat gcccgcaatg
     8041 ttattagcgt tatatcatca tgaacaatta ttatggaaaa aattagatac aggagaaaaa
     8101 agccagatta ttcattggtt ctcgcaaatt tttgaatatg aatgtgcaga tggtaattgg
     8161 caatttttta agataattgt cggaacaatt atccaaaaat ttggttatcc agttaaagaa
     8221 tcagcactga aagaagcatt tgataatata gaaaattgtt atcttcaaaa tggctggtat
     8281 cgagacagtt caagaggtcg ccaagattat tataatcctt ttgcatttca ttattatggt
     8341 ttgatttata gcgtactaga accagaaaag cccattagcc agatatataa gaaccgagct
     8401 attgattttt ctagagacta tattcatttt tttgcggaag atggtgcaaa tgtgcctttt
     8461 ggtcgaagca tgatttatcg ttttgcagtt tcaagctttt ggtcagctat gttgtgggcc
     8521 gatcttttgc cttttaaatt aggtgaaatc aaggggttag tcaatcggaa tataagatgg
     8581 tggatgcaaa aagaaatatt tgatgaaaaa ggtatcctga atattggtta tacctaccct
     8641 caattgacat tgactgaacc ctataatagt acgttatctc cattatggct gaataagatt
     8701 tttttattgt tggcgctacc tgaagaccat gagtattgga cggctaaaga aatgcctatg
     8761 cctattcgtg aaggaactaa acttctttca gaagccaatt tgctcataca acatgataat
     8821 ggacatacat tttttttgaa tgcgggacaa ttagggccaa atttccatac attgaccaat
     8881 gaaaaatatt taaaatttgc ttattctagt caatttggtt tttcgatacc gcgagcgaat
     8941 caattgaaag cagaaatggc aatggattca atgctaggga ttcagcgagc ggacacatat
     9001 atcacgacca gttttaagaa tgagagcatc aaaacctatg gacagttcat cgttcgaaat
     9061 aatgtacgag acattgtatg taagaaagag gtacttgcct ctacatggga acctacttta
     9121 caggcaaaaa tcagaacttg gcttattcct tttgaaggct ggcagattcg cgtacacaaa
     9181 gtagaattag atacagaata tgttctatat gagacagggt ttgctattga atgttctcct
     9241 gagaaagaag gaataatcat agaagaagac aaggaaaact atagggtgag tgaagctggc
     9301 ttttcaggta ttatctgttt aagtgacgat actattaaac gaaaatccac agctattatg
     9361 ggtttgccca atacaaactt gatgacatgg gaaaacactt ttattcctgg attagagggt
     9421 acatttggaa aaggaaccca ttggctcgga acaggagtgg ttgctcatca agatcgggat
     9481 tatagtttag aagtatggaa caatcgtccc aaaattgatt ttgatgggac aaccgggcta
     9541 actatccaaa ataaaaacaa taaaaaaaga ctaaaattat gctaaaggct ggtggggaaa
     9601 tgcttgataa agtgatgttt gaagagataa tacatccaga aaaatggata aatgaatgtt
     9661 ataaagaatt aatggaaaaa gaatggaata atgagatcga gcgttgtcgc agacacacgg
     9721 agaggttaat caaacgtatc agtaacagtc agtatcaatt cccaagcgag tgtcctataa
     9781 aaggacgtta tccattaaga gacaatattg gttggacaga aggattttgg acaggaatta
     9841 attggttgtt atttgagaag acgggtgatc ctttatttca acaaacagct gaaaaagcag
     9901 atatagattt tatccacagg attgactgtc aaattatcac taatcatcac gatcttggtt
     9961 ttttgtattc tttatcaacc gtagcagatt ataaaataac gggaaatcga aaaatgaagg
    10021 aagcttcaat tgatgctgca gaaacattac ttcagcgttt ttgggagaag gcaggagtta
    10081 tacaagcttg gggagatcct agtgatcctt cacaacaagg tagaatgatc atggattgtt
    10141 gcatgaatct tccattattg tattgggcga gtgaagaaac tggaaatcaa aaatataaaa
    10201 aagctgctca ggctcatatt caaaatgcag cagattattt agtaagagaa gatggttcaa
    10261 cttatcatac attttatatg gatgtcaaag atggaaaacc aagatatgga agtacgcatc
    10321 aaggttatag tgataattcc tgttgggcta gaggccaagc atgggggatt tacggttttg
    10381 cattaagtta tcgttatttg aaagaacaaa aatattttga tttaagcaaa atattagcca
    10441 attattttat gaatcggttg ccagaagata ccatttgtta ttgggatttg atctttgatg
    10501 attctagcag agaagaaaaa gatacatcta gtatggtgat catggtttgt ggattattag
    10561 aattaataga atcaggtcta ttagacaaaa cagaaaagaa cttataccag tctgctgttt
    10621 ggaaaattat gcgacaattg aaagaaagat atgctacaac ggaagaagaa gatggctttt
    10681 taacacagtc tgtttataat aagcccaaaa ataatggggt aaatacacct tgtatttggg
    10741 gtgattacta ttatttagaa gctttagtga gaatgactag taattggtct tcttattggt
    10801 gaaaaaggta aatatggaat ttttgtttga taaaataaaa aaagaaaaac caaaacagca
    10861 tgaatggttt ctgttttggt tttttcgtta attttcatat tcttctaatt ccaagcttag
    10921 ttcttcccat tccgtcaatt ttgtttcttg atcttgtcta gcagcttcta aatcttggtt
    10981 cagctcattg agttttacgt gatcttccag gttttctggc gcgaccattt cttgttccaa
    11041 ctgatcgatc cattcatcga tccgcgccat ttcttcttca acctgagtaa tttttcgttg
    11101 aaggctacgg ataagctttt gctgttcttt gctttggtaa taatcagatt tgttcgtggg
    11161 agcaggagca gattctggct catcttgtgc caacaattcg gcgatttctt cttcttcctg
    11221 ctttttctct aaataataat catagtctcc tagatagact ttgctgccat tttcagagag
    11281 ttcgacgact tttgtcgcga tccgattgat gaaatatcgg tcatgggaaa caaaaagcag
    11341 tgtgccgtca taatcgatca atgcattttc taatacttct ttgttgtcaa tatctaaatg
    11401 gtttgttggt tcatccaaaa tcaaaaaatt ttctttgttc atcgctaact tggctaaagc
    11461 aacccgtgct ttttcaccgc cacttagcag agggattggt ttttctacat cttcgccaga
    11521 aaataagaaa gcacctaaag cacttcggat ctctttttct ggagtggtag gatgctcatc
    11581 ccacaattct gctaggatcg tcttgtttgt atgcagatca gcttgacctt gatcgtaata
    11641 gccgatggtg acatttgtcc ctagcgtttc ttttccacgg ataaaaggga tctggtgaat
    11701 gattgatttc agcaacgtcg atttcccgat accattcgga cctactagag caatcgcttc
    11761 ttgacgacgg atatctagat tgattggttc agataaggtg acattatcat atccgatagc
    11821 ggcatcttcg atttgcaaga ctacatttcc agaaggcttt tctatactga atagaaagtt
    11881 tgcttgtttt tcatcccctt gaggacgatc cagccggtcc attttttcta atgtctttct
    11941 gcggctttgc gctcgttttg tggtagaggc gcgaacaagg ttccgagcaa cgaagtcttc
    12001 taatttatgg atttctgttt gctgcttttc ataagccttc cattcacttg ctaactgttc
    12061 tgctttcaaa tctagatatt tcgaatagtt acctttgtaa tggcgcattt ttcttctgct
    12121 taattcatag acttcattga ctactttatc taaaaaataa cggtcatggg aaacaatcaa
    12181 taatgcacca gtatagcttt gcagataatt ctcaagccag gaaagtgtct cgatatctaa
    12241 atggttcgtt ggttcatcta gaatcaaaat gtcagggtgt tgcaaaagca tgcgagctaa
    12301 agctaaacgt gtgcgctgtc cgcctgataa agtatcgatt ttctgatcat aaaatgaaga
    12361 atcgaattta aacccatgca atacggaacg aatttcattt tcataaccat agccgtttcg
    12421 atctgaaaaa tcgtgttgca gccggtcgta ttcttttaaa taagaactat aagcaggtgt
    12481 gtctggcgta ccttcgctaa tgaaaatctc tagctcgcgc atccgctctt ccatttgtct
    12541 aacttgttca aaagctttca gcatctcgtt ccaaactgtt tcattggaat caagtcctgt
    12601 gtcctgagcg aggtatccga gagtcgctgt tttattttta gcgatctttc cttcatcagg
    12661 tgcttcaatt ccagcaatga tctttaataa agtcgatttt ccagcgccat ttctgccaac
    12721 taaagcgaca cgagcgcctg tactgatttc taaatgtatg ttttcaaata agacttctgc
    12781 accaaaatgg cgagcaatct gattggcttg taataatatc atggaatcct cttttctact
    12841 ttgtgaattc tcctcaaata aaaaactatt tttcaattag tagtctacca taaattccat
    12901 tatactgcga gatttgcaga aatgataaat aaatgaataa agaataaaat ttcacaatat
    12961 ctgagcaatg gaattgattt tttcctataa atactgctat gatggagaaa tcaaagatgt
    13021 aattagacaa tacgtggagg tcatttcgtg aaagatcata ttattccaaa ggcgacagct
    13081 aaaagactgc ctttgtatta tcgctattta aggattttaa ataatgctgg aaagaaaaaa
    13141 gtgtcttcaa ctgaattaag tgaagccgtt caagtagata gtgcaacgat ccgtcgagat
    13201 ttttcttatt ttggcgaatt aggaaaacgt gggtatggtt atgatgtaga agatcttatg
    13261 cacttttttg caaagacatt aaacgacgat caattgacaa atgttgcgct gatcggtgta
    13321 gggaacttgg gaagtgcttt actaaaatac aaattccatc aaagtaatag catacgtatc
    13381 agttgtgctt ttgatgtgaa tgaggaaatc gttgggcgca tcgtagacgg tatccccgtt
    13441 tatccaatgg aagatatgtc agaacaaatc aagatccaac aaatcgaagt agcaatttta
    13501 acgatacccg ctgaaagagc acaagaagta gtcaatcagt taacggaagc aggaatcaaa
    13561 ggaatcttga actttaccgc tgctcgattg aatgctccgt cagatgtatt gatccaaaat
    13621 gttgatttga cgaatgaatt gcaaaccttg atctatttct tgcattctga cgcaaatgcg
    13681 cattccgaaa atacagcaga ataaaaataa aaagcgattg aacaaatgaa ggcaaaactt
    13741 tcacttgttc aatcgctttt ttctgtttgg acaacgatta ttttgttcgg aagatttctt
    13801 cataagaaag ggaatcatct tctgctgtca gttcatctag tagataacgg atttttttaa
    13861 agtcgatgaa ccgtgcttgc cgaaagactt cttttccttg atgaaaaatc aggacaactg
    13921 gcgcagtcag cacttcaaat ttactagcta cttctggtgt ttcaaatgca tccaaatgaa
    13981 gtgccggaat atcataatgt gtgagaagtt cctctagtcg tggacgaaca gcgtgacaaa
    14041 cactgcaatt aggcatcgaa agataaatga cggcaacgga tgactgttgc agtatgtctt
    14101 gaacttcagt caagttagtg gtttgtttca tttttattct cccttttatg atagaagtga
    14161 tatgtatgag accttaattt aatgggaata acagaaaaag tcaattgaag tgctttggta
    14221 aaaaataaga gttgtgtaaa aatttacaga gcaacttgtt ttttttgaat aaaagcgtat
    14281 atttgcaaag cgaatgaact agaaataaaa aggaggaaac tcatgttttc ttttattcca
    14341 aattcggttt tgcagatgag tacgattttc ttatcgatcg ttattgaagc attacctttc
    14401 gtattattag gctgtcttat ctcaggcgcc ttacaagtat ttttgacccc agaacgtgtg
    14461 aagagatggc ttcctgaaaa tcgtatcttc tctattttta ctggttcgat cttaggattt
    14521 ttctttcctt catgtgaatg cggcatcgta ccgatcgttc atcaatttgt taaaaaaggc
    14581 gtaccagttc acacagcgtt tgcttttatg ctgactgctc cgatcatcaa tccaatcgtg
    14641 attttttcca cttttatcgc atttggcaat tcttggcaga tggcaagctg gcgggtgata
    14701 ggcagctttt ttgttgccct tgtgattggt gtctggcttg cctattttca aaaagacgct
    14761 gtattgaaag aaaaaatcac gtctaaagta gcagaaaatc accatcatca tgtccatgaa
    14821 gaagaacaaa gtgagaagaa tgaaccaaaa aatcagctga tccatcaaac tgggcatgtg
    14881 ttgacacatt caatcgacga attttttgat acaggtcgtt atttgatcat tggcggatta
    14941 atcgcagctg cgatgcagac ttatttacca actagaatta tgctaacgct cggctcaaca
    15001 aagattttag ccattatcat catgctgtta ttggccttta cgatgtctct ttgctcagaa
    15061 gcagatgcgt ttataggatc ttctttgtta agtctgttcg gcacagcacc tgtagctgcc
    15121 tttttggtct ttggcccaat ggtcgatatc aaaaatctac tgatgatgaa acgatatttt
    15181 acaggacgct ttattttatc gctgatcgga ctgattgccc ttagcgttat tggattcaca
    15241 ttatttattt aggagggaaa atatgctgcg gtttttgatt ttatctgggt atttcgaatt
    15301 gatgatgtac ttgcaagttt ctggcaaact cgatcaatat atcaatgtcc attatcgcta
    15361 cttagctatt ctttcaatga ttttatctgc tcttttggct ttagttcagc tgtatttgtg
    15421 ggtcaaaaac ggaaaagcag aagaaaaggc acacgagcac gatcatgacc atgggttgtc
    15481 aaaaccttat caacgtggaa tcgcttatgt actgctagct ttgccagtaa tcgtggggac
    15541 gttgtttcca acagttagtc tcgacactac gatcgtagaa gccaaaggat ttaatttccc
    15601 agtaagtaaa gaatcagtag gggatccgga gatgcagaca caatacttaa agccggatac
    15661 cagtatttat ttcaacaaat cagactactt agaccaaatg aatgagttga aagaaaagta
    15721 tggggataag caaactatca agatcacaga tgaaaactat ttagaagtta tggagctaat
    15781 ttataattac cctagcgaat tcattggcaa aaaaatcagc tatgaaggat ttgtttacca
    15841 aacaccgaac gatagcaata cagatatctt cttgttccga ttcggcatta tccattgtgt
    15901 ggcagattca ggagtctttg gtttgttgac gcatatgccg gaaggagtaa cggttaaaaa
    15961 tgatgaatgg tataaaatag aaggaaccat ccaatcagac tattatcaac cattcaagcg
    16021 tgaaatccca tctgtagttg ttacaaacgc tgagaaagtc tctgctccga aaaatcagta
    16081 tgtgtatcgt tctttttaaa agaacaaaat aaataaacat agctcagaca gctgacacgc
    16141 aaggacgtcg gttgtctggc tttttttgca tgatgtattc atttgtttga tatttatttt
    16201 agaagcagca tcctgaaagt atttgatatc ggtttcaaag gtgttggaaa agattgtgaa
    16261 gagaattaca atttattcct aacatgtatg ttgaaaagtt gtatgaaatg attttgatag
    16321 taaaatatcg agtggaggta ctttttatgg taacgcgtat atttattttg gatgatagtt
    16381 tggtttttga aaaaatgcta gtagaaattt tggaagaatc cagaatttta ttaagtcctt
    16441 ggaaatttga gatcgttcag ggattgaacg ttatacaatt tgttgaattc attaaaaata
    16501 atgaaatcta ttcctcagat atttttttcc tagacatcga tttgaacgcc tattatagcg
    16561 gtatcgaact aggcgaaatg cttagagaaa agaatgaaaa gtgtaaaatt gtttatctaa
    16621 cgtctcatcc gaataaagca ataactgtta ttaatcgaaa gattacgcct agtggttatt
    16681 tgataaaaga attcacttat gaaaaaaata aaaaaagcat ccaaagttac ttattgaaag
    16741 aaaaagaaaa ctatcctgtt caacatgcta cgaaaaaaag gtggacaact gtccgttatg
    16801 gtaatagcga tcactatatc cattacgatg aaatccttta tctaatgagc atgccaggtt
    16861 ataaaaataa aataggccta gtattgaaag atgaagagat tctcgtaaac ggcacaatta
    16921 aaaaatataa aaaatcactc gaatatgagt atttatgtaa agatttaaaa gcttatatca
    16981 ttaatactga aaacattaca tctattagca gagtaaacga aatagtaaca tttgcaaatg
    17041 gagaacaact agagatggga aagagaagta ttgataaact aaagaatttt atgcaagaaa
    17101 agatagaaaa tgaatcattt taaagaaaac aaagactcat atcttacctg ttagaagagt
    17161 gttttcctgt agaagagaac aacccaagta gcagcctagt cgtttctatc cttttttgtt
    17221 atgcactctt tttgacattt actccaccaa taacgaaggg tacaataaaa agtaataaca
    17281 aacaaaagga gtacagaaat gattgaattc atcaatgtaa gtaaaagtta cgggaaaaaa
    17341 caagcattaa aagacttgtc tctctcgata agacaagggg aaatttttgg atttttagga
    17401 cataatggtg ccggaaaatc aactacgatt aaaagtttag ttagtattat tgaaccatca
    17461 tcgggaacga ttttagtaga tggaatgaaa ttgacggaaa atcgattgag tatcaaacaa
    17521 aaaatcggtt atgtgcctga ttccccagat atttttttac aattgacggc tggagaatat
    17581 tgggacttga tttcagctgc ctatgaatta gacacacaaa aaaaagaaaa gcgtttagca
    17641 gaattgacag cgctttttga tatgtatagt catcaaaatg aaacaatcgc aagtttttca
    17701 catggaatgc gtcaaaaaac gattttgatc ggcacgttgc tgccagatcc agatatttgg
    17761 gtattggatg aacctttgca aggacttgat cctcaagcag catttgattt gaaagaaatg
    17821 atgaaggctc atgccgcaaa aggaaaaaca gtcatttttt ctacacatgt attggatacc
    17881 gcacaacagt tatgcgataa actggctatt ttgaagaaag gtgaattgat ttatcagggg
    17941 gcagttagtg aattattgaa tggctcacct gatgaaacgc tagaaaagat ttatttgaaa
    18001 atggctggaa ggcaagcgac aggagatgga ccgtatgtat aagcgacaat tattagaatt
    18061 aattcgagtt aatcttttat atgttaatcc acagctcacg aataaagcaa gagagaaagg
    18121 aaaaaaggga aagcgattaa ctatctatct tttgtctcaa aatctttttt cagggctgat
    18181 ttttttactg atttacggat ttgctatgtt tgctatgaac tttgttaaat tgccaggttt
    18241 ctttacttat tacgtggcac tttttggtat gttaggttta actcaaagta tatcagtcat
    18301 ttataatatc ttttttgaag gaaatgacct gcaagtattt ttgcctctgc cttttggaca
    18361 agaacaggtt ttttcagcaa agattttggt agttgctttg accatcattc cttttgtttt
    18421 tccgcttcta gtcatgttta ttttaaccgg atggcgagct gatctaggga ttttgcttac
    18481 tatcattatc tcaatccttt tgttttctct atttttgatt attctttttt gtctggctag
    18541 tttgattgtt tttggtttgg ctcgaacagc agtgtttaaa aaacatagaa aaacagtttc
    18601 tagtatcttg cttggcagct cgatgctgat cgcatttgct ggaatcatgt ggatgaatca
    18661 tcaaacgggg actattgaaa atgagttaac agatcggcat ccgatttcga tattattgcc
    18721 attctatgat gctgccagtc agccactttc tcaacaaggt ttattgggtt ggggaatact
    18781 agctatcacg gctctgggat ttttccttgc tgtaaaacag ctgatagtac caaagcttac
    18841 agagcaactg actgattcaa acagtgagtt caaaataaaa agaacccata aaaagaacca
    18901 aaatgtgcat cagcttttat ttagttacaa tgctcaatta gtaaaagaac ctaatttgat
    18961 tatgcaagtt ctttcttctt ccttgttaac tccaatcatt tttattcttg cttttgccct
    19021 aggaggcgaa ataaaattaa ctgatttaga taataagtta atcggtgttg ttttcctggt
    19081 agggatcgca ttggctttct taacagttaa tcagacttct tttatcagca atcttatttc
    19141 tttggatcaa gaaaattttc tgtttatccg ttctttgcca atctctatga accaatattt
    19201 aaaagaaaag ttcagattcg gatggatatt gcagagtttt ttaactggtg ggatcgcatt
    19261 attaagcgga ctgtcttttc agctgccttt gttttttatc cctagcttgc tatttggttc
    19321 tttattcggc tgctacttat tgtcactacg ttatttcgct agagattatc ggttgctgct
    19381 gctgaactgg accaatatta accaattatt taacagaggt tcaggaagtt tgggtttagt
    19441 cgcaactatg atgggttcat tgatcatcag tattattctt atcgtcttat acggaatgtt
    19501 ggctttgttt tatccatttt ggttagtgaa tattcctgtg atcggtttag ttctaatact
    19561 ttccgctcta tggatcgttt attatcaacg aacgttttgg aaaaaatttg aataaagaag
    19621 aggggccgtg acaaaaatca tgtcgcagcc ccttttttac agatagaggg tgttcaaaag
    19681 tcagtttctc agtattaagt caattttatg taaaaatgtg agaagctatt tttacaaaac
    19741 tttttttaat actcataatt acttcttatt gctcctgcgg ttacttgtcg caatgtttgt
    19801 gagatatttt gtcatcgctc aaggctgaac gtctctttca caaccttttc tttgttacac
    19861 ttcgtttatt taaaaagccg tttttttcgt ttcatcatga ttgcgtcacg ctttactttg
    19921 aaattacgga tgttatggtt aaagacttct gataatacaa gacctaaagc gattgctcca
    19981 gcaatcataa ttgcttggac cgcataatga gccgcttctc gataggattc agtaacgaga
    20041 tttcgaaccg cttgataagc taaaccacca gggactagag gaaccatccc gggaatattg
    20101 aaaatcgtta cgggcatttt caaacgttta gagaaaagat cgctgatgaa tgctactcct
    20161 aaagaaccaa gcaatgaacc aaaagcagca gatccgccta tttgaacaca gatccagtag
    20221 atcatccagc caaaagcacc agaaagacca caacaaatca atgaacgcct aggtacattt
    20281 gtaataacgg caaatgccgc agtcgctaaa aaactaaaag aaaactgaat aaatatcgtc
    20341 cccatacttg tgttcctttc ctaataaaaa agctggaaaa taaaagcaat cgcaaaaccg
    20401 atcatcgtag cagtcatcat cgcttctgtt ccgcgagaaa ctcctgagac ataatgtcca
    20461 gctagcaaat cacggatagc gttcgtaatt tgaactccag gaactaaagg catcacacat
    20521 ccgataatga ttagatcctg attgcttcct aagccaaaac gtacgctgta gatagcggct
    20581 atgccaatca ataaagaaga taaaaattcc gataaaaatt tgattctaaa aaatttcaaa
    20641 ctatatagat aagctgcgta tcccaatcct ccaatgacta aagtcacagg taaatcggtc
    20701 atctttccgc caaataacac cataattgtt ccactgatca ctgccgcgct aacgatttgc
    20761 aaccagacag gaaagaaaga acggtctcgg tcgattgctt gcagttcgca gtaaagttct
    20821 tctaatgtta gctctgaagc aacatattta cgtgaaagat catttacttt tactactttt
    20881 tctaaattaa tcgaacggtt ggtaatttgt tccattcgga tggtcgaggt acgatcaaga
    20941 ccaataaaga gaccggtttg agtgacatag ctgaccaaac ggaaatttcc agaagctaaa
    21001 gcaattcgac tcatcgtatc ttctacccga tacatctccg cattgctttc catcatgatt
    21061 ttcccagcga gtaaacaagt gtccagcaac agatctaatt cttttcccgt catagcatct
    21121 tctccaataa ttgattgatt agttttattt tactacaaaa cataccagaa gcgtaaagaa
    21181 taaaaaaact tgaggaagga ataaaagagg cgtatactgt ttttgtattg cgggtgtagt
    21241 ttagtggtaa aatcccagct tcccaagctg atgtcgcggg ttcgattccc gtcacccgct
    21301 taaaataggt tgtgaaaaag ctgctctgca acaagtaata agaacagcca agcaaaaaca
    21361 acttcttatg tttttaactt ggatggactt attaccgcag atgcaagctt ttgcgcaccg
    21421 tttaccaagc ggttgtgaaa tcagtgtatt gtcttgagta tgaagaaaat ttttgaataa
    21481 taataaatac cttacagata gagtggtgac tgattagaga cgaggaatcc gtctcttttt
    21541 tgtattttta agccatctta aaacaggttt tattttttgc tgtttctatt tctttctagt
    21601 atttatttat aggggaacat atgttaagat ttagggagct gttagtaaag gagtaaagaa
    21661 atgagcaaaa aaacaaccaa ggcgatcgtg gggatcgtcg ctgctgtgat tgcaggggca
    21721 ttcggtgttt ccaccacaca aaaagattca gatatctttc agcagattac aactattttt
    21781 gattccacac cacaagcttc tcaagtagcg gatgtgccag aatatgatgg aaaacatcaa
    21841 gaaatagaaa tcaatgggaa tcagccggaa tttacaaaag aggatcttag cctttccaaa
    21901 ggaacatggg aaagctattc aaatattgat aaattgaaca gagtaggaca agccaatgct
    21961 atgcttggaa aagatttgtt ccctactgaa aagagagagc ctttgtatat tgacccgaca
    22021 ggttggaaac aaaagaaatt aagtgacggg caatggttat ataatcgcag ccatttaatt
    22081 ggtttccagc tgactggtca aaataacaac attaaaaact tgatgacagg gacacgttcg
    22141 ttgaatgctc catacatgct tgctcacgaa aatgatattg cggcatatat caaagaaaca
    22201 aatcatcatg tacgctaccg tgtcactcct cattttgagg ggaatgaact ggtagccagg
    22261 ggagtgcaat tggaagcaga aagcattgaa gacaaaaaaa ttgaattcaa tgtctttatc
    22321 tacaatgttc aagatggcta cacgatcaat tatgagacag gacaagcaac aaaaacaaaa
    22381 aattagtagc agctattcga attttttatg aatattatga aaaaattgtg taaaaacata
    22441 cattcaaaga aatatagcgt atactttatg aaaagagtac ttttgataaa gctacagaaa
    22501 aaaggaaaaa aacatacaaa tagtgtttct taatttattc ggaagtttgg aatatttgtt
    22561 tgtagttttc cctttcttcg agtaaaataa ggttgtagaa ggtaagctgg aattaccttg
    22621 cgggaaagag gtgtagaatc atgggtttta cagatgaaac cgtacgtttt ggttttgacg
    22681 atagtcgcaa aaaagaagtg agcgaaacat tagcgattgt ttatcgggct ttggaagaaa
    22741 aaggctacaa tccaatcaat cagattgtcg gctacttgct ttctggagac ccgtcctaca
    22801 ttcctcgtta tcgtgatgct cgaaatttga ttcgccgtca cgaacgcgat gagatcatgg
    22861 aagtaattgt caaggactac ctctcaaatc atggagtgaa tttatgagag taatgggctt
    22921 ggatgtcggt tctaagacag taggtgttgc tatcagtgac ccctttggct ggacagctca
    22981 aggagtagag atcattcgga tcaatgaagc agaagaagag tttggctttg atcggttgaa
    23041 ggaattagta gcacaatatg aagtagaccg gtttgtagtt ggattaccta aaaatatgaa
    23101 caattccatc ggaccaaggg cagaagcttc catgtcatac ggagaaaaga tcaaagaact
    23161 attctccttg ccagttgatt atcaagatga acgattaacc actgttcagg cagaacgtat
    23221 gctagtagag caggcaaata cttcaagagc caaacgaaaa aaagtcatcg ataaattagc
    23281 agctgtgatg atcttacaaa attatttaga cggctcaggt aagcaattat tttaataata
    23341 aaagaaaaga ggtaatctta tgacagaaca taaccattcc cacgaccatg aaggacacga
    23401 acacatcaca ttggtggatg accaaggaaa tgaaacatta tatgaaatcc tactaacagt
    23461 tgacggacaa gaagaatttg gacgtaacta tgttctttta tatcctgctg gtgtttcaga
    23521 agatgaagat gtagaattac aagcttatgc atacatcgaa aacgaagatg gaacagaagg
    23581 cgagttagaa caaatcgaaa cagacgcaga atgggacatg attgaagaag tattcaatac
    23641 attcatggcg gaagaagaag aatagactat aaagctagga gaaaccttga tatgataggg
    23701 tttctccttt ttttattttt tactgtatgc catattgtat gccatctagt caatatttaa
    23761 gtgttgtact aatttttcaa cagtcttttc tttcgtttct tttgccaagt gaccgtaaca
    23821 atcgatcgtc tgactaattt ttgtatgccg taatctagtt tgaacttcta ccatagtagc
    23881 tccagcgtcc aagagcattg aagcatgagt gtgtcttgct acatgcacac cgagaaatgg
    23941 aaccatagct ttttcacaaa tagtaatcaa tcttgcataa atagcgtggt gtgtgattag
    24001 ttctttatag ataccacaaa aaatcatagt cggatcagtt acaccaagtg tcagcatata
    24061 tttccgctga ttaatctgcc atttttttaa tatagaaatt gttctttcat ctagtggaag
    24121 aaccccagca ctacaatcag ttttaggatc actgatttta tagccatttt tggattggct
    24181 tagtgtttta ttgatggtga ccgtattttc ttgaaaatca atgtctgacc aattcaatgc
    24241 aagggcttca ctgatcctaa ccccgctata aaagagaaag cgtagtaacg ttttatcaaa
    24301 gtcgtttcga taagtttcag gtttgctgtt taggtaatca aacaaggtga tcagttgttc
    24361 tttactgtaa actttgacct tttctttatg cttagtggtg gttcttttag gcattaatac
    24421 gttgtctagt ggattagtct caataatccc aagattgata gcgtagctaa aaatacgctt
    24481 agaagttgaa tgaagtacct tgtattggtc agtagtttca gcccagctat ttacaatttg
    24541 ttgggctttt tttaccgtga cttcattcac acgaagattt ccatattttg gaagaatcca
    24601 ctttctaaac ttgatttcag ttttcatgaa ggtggcttct cggacagtgg ttttatatgt
    24661 ttctagccac aagtcataaa cttctttaaa cgtttcgttg ttcgcttttt taataccgtt
    24721 tttatcgtag tccacttgca agcgtgacaa ggcaagctgg gcttcttttt ttgttttgta
    24781 acctcgtcta cgaaccttat caggtttgcc agtcattttg ttcattccaa gataggcttc
    24841 atagagccaa aatttacctt ttttagtttc atattgcttg aatgttgcca taatagtttt
    24901 ccctccatag tgtagcaagc cgtgggggcg gttggaggag gcagtttatt attattttga
    24961 atagtgttta tttagctcag taacaagagc tgtgaactct tttagaagat cattttcata
    25021 aaattcttga tactcttttt tctcatctgt atttttttct gaatcattaa ttaatgagtc
    25081 atatcgtaaa agcgtattta gaagagctgc gagataagca attggggtac tcccgtcagg
    25141 aaattcaatt cgagatcctg ttttaagata ttttattgcg tttgttaaat aaatcttctg
    25201 tgagacagtc aggttatctt cttcgatgtt attgatagca ttagaaagat tagaatcaat
    25261 tatagagtta tttttttcaa tagttttttt caattgcttt tcaagcacat ttcgcttaat
    25321 ttcgggcatc atatgcatat ctcttaatgt ataagatccg tttaatagat aggtagtgga
    25381 tacatctaat acctttgaaa gttgtttaag cctggtgtta ttgggaagat tatagccatt
    25441 ttcccaatta ctaacggcac ctttactggc cggtggggat aatttacctc caagttgttc
    25501 cattgagagt cccttttcaa ttctagccag tctaattctt tgtcctgtct ccactgcttc
    25561 ggggtatttt tttctagcca cattttcacc accattcata tattttctct actatatcac
    25621 gatttaaata tgtgtgaaac ataaaagttc aaaaaagtat gttaaaattc ttgcaaatga
    25681 aaaggtatga tggtatattg agtttataag aggtatagaa atgtattcaa gagcctcttg
    25741 cattttttta aaatctttgt atagaaatgt atgctaacga ggggggataa atatggaatt
    25801 aaaaattgac aaactcacgc ttgatgatcc agcttttaaa attattgacg atcgagttgt
    25861 tcaacaagta gagcaaactc aaggaacgtt actttcatta ttagaaaaaa agtaccagtt
    25921 tccaaaatat atgaacaagg cacaagctgc taagtatatg aacgtttcat acaatactat
    25981 gatgcagaaa tatgttccta acggtttaaa gttgattata gttgatggag tcgtaagaat
    26041 ttcacaagat gaatgtgatc gctttatgga agaataccaa aaataaacgc aagccgtggg
    26101 ggcaaaggga ttaataggag gaaataataa tggaatcgac acaaaataaa gcaatcgaaa
    26161 aagtattatc aacaattctt acagaagaca cagcggcaga attagcaaac ttggaaggca
    26221 aagcgctaga agaaacgttt gaatgtttgt acgaacaaat ggactatcaa aaattgctac
    26281 cacaagaacc aacggtaagc ggagtattgc gtggcttgaa cgatttagta caagcagagt
    26341 ttaaagaacg actttctatt gaagagtatc aagaaatttt gtatcagcaa gttgagttgt
    26401 tagcgagctt gctagggctt gaactggagg acgttgaatg aaaactgaaa tttggaacgg
    26461 acacattata agatttgtcg atattaatga tgaatggtgg gcagtggcga aagatgttgc
    26521 ggaagcgtta ggtcttaaac aggttactag agccattcac tctttgccta aagatggggt
    26581 tactactagt aaggtcatcg attcattggg cagaacacaa gatgtaaaca tcatcaacga
    26641 aaaaaaatat ttaccgcatg gcattcaaaa gccgtaaaaa agaagccgag gcatttcaag
    26701 actggatttt cgacatcatc aaagaactac gccagtccac aggacttgaa ggctttcaag
    26761 tattccgcat gctagacaaa gaacaccaaa aagaagcaat gactaaatta agccacgcta
    26821 ttactgaacc aaaaccagta gactacatta aagcgaatgt gatagccaat aaagctgtat
    26881 caactattta tggtcattcc aaaatggtaa aaaagaaaga tatgactcct gaaatgttgg
    26941 ttgatcgtga acctatttta gatgagacag tagaattaat gactgttaaa gaaaaatatg
    27001 ggttgcagtt ttcagtgagt gagaaaattt ataatcgttc tgctgaattg cagacaactt
    27061 aggagcatta acatgatcga gaacaaagaa aaagccttat ccataacagt cttggcggac
    27121 aggataaagg caacttaatt gggataaaac ccgatattct ttgttccgat tataccatat
    27181 taaaaaatcg gagggaacca ttatgaaacg aaacttaatt ataggaagca ttttaatcgg
    27241 cggaattttc ggcttattac cattaattgc aaaaatagct atctttgcag gattagcgtt
    27301 atatctcttc actgcttatg acgagtacga ctatcaatta agaactggag ggcataagta
    27361 gatgtacaaa acaaaactat taaaccaact cgatagcctt gaattagagg aaattaatca
    27421 agggatcgct gaactagaaa ataatatcgg gaaaacctac tttggaaatt cattcaatga
    27481 aaaactaaca gttttgtatg tactcaaaaa acatgcagaa cacaaaataa tttgtcgaga
    27541 aatcaacgag ctaaaaaatc agattttaac cgcatggtta aacattactg atatgcaaga
    27601 agcaagggtg aaaacattta atacatgggt aaagtatcag aatcaattaa aaggtgctga
    27661 atttgttcgg gatgggttga aatacgaact tgagcagttg aagctcatgg aggtgtctga
    27721 atgatttata ccagtatttt gaaaaaggag gagaggttta ttggcaaata attatcaagc
    27781 agcaacggaa ttacaaaagt cgggatggtc aatttatccc ttatctcctg gaactaaaat
    27841 tccaataaaa ggctctagtg gttggaatga tgcaactaac gattctaatc aaattaatga
    27901 atggtggacg gaagatgcaa ctagaaatat tgggttaatg cttgaagatc atcaaatggt
    27961 ggtagttgac ctagatcaac attctgaaac acgaaacggc gttgagaatt ataaaaaact
    28021 tgcttcaatg tatgatccat ttccttctac ttatacggaa atcacaccag gtaaaggaat
    28081 ccatttcttc tttaaaattc ctgatggtgt aattatccaa caagaaacag gtgcatttgc
    28141 tgatatcttc gggcgtgatg ataaaggtaa aagtttaagc gggattgata ttatcactaa
    28201 aggagttcca atagcgccaa ctatgattat ttcaagaagt gttgggagag catatgaacc
    28261 tattgaaaac gtatctctaa ataatattgc accagctccc gattggctag tgaacctact
    28321 gctaaaaaaa ccgcaagaaa taaagactca ataccgaccc gtagcaaaaa cagggacagc
    28381 aaaaaaatta gatatgattg ttcaaggcgc tggcgaaggt agtagaaacg atcatttaac
    28441 taagttatgc ggttggttac tatggcacgg tgtagataat caaactttag cagaattgat
    28501 ttatacagca aatgcgtaca atgaaccacc gctaaaagat aaagaagtga atcaaattat
    28561 tcgatcgatg attaaaaaag atttgagggg gaaagctcat ggctcataag cataaattag
    28621 atagtatttt agactttccc gaagccagcg agcgtgaaga caatatcatt gaattgaaaa
    28681 cctggatgtc acgattaaga tgcaataaag acgatcagat taaaagtaac agtgttgtga
    28741 atgcagaatt gattttaacc aatgatagca atttagctgg aacaattgct tataacgaat
    28801 ttagcggata cattcaccta ttaaaagatt ctccttggat caatcgtacc gctggagaat
    28861 gggaagacag ttttgaggat gccttaacgg catatattga agaaaactac aatgtagttt
    28921 ttgatgacaa caaaatacac aaagcagtag taaatgtggc tagaaagaat gttttcaacc
    28981 cagtaaaaga acgtatcgaa aaagttaaat gggatcaaca gcctagactg gaaacactgt
    29041 ttattgacct tttaggggta gacgacaacc tttacacacg agaagtaaca aaacgttgga
    29101 tagtcggatc agtcgcacgt atctataaac caggaataaa gtttgagatc gttccagttt
    29161 tggatggacc gcaagggatt ggtaagagta ccgttccagc attactttac acggatgatt
    29221 ttttcaccga ttcattagat tcgctaggtg aaaagaaaga tgattatatg cagcttcaag
    29281 gcaatgtaat tattgaactt ggagaattat cttcaatgaa caaaactaaa attgaacaga
    29341 taaaaaactt catcagtgcc aagatcgata aaattagacc tccttatggt cggaatgtca
    29401 tagcttgggc aaggcaatgt gtatttattg gaacgtcgaa tgatgggcag tatttgaaag
    29461 atgatacagg aaaccgccgt ttttatcctt tgccttgtaa gaataagcca aagatgaatc
    29521 cgtttaaaac aaaggatgaa tattttcttc aagtgttagc tgaagcaaag gtgctttttg
    29581 ataaaggaca acgaatctat tttagtcccg atgaagataa agaagtctta gaaattgcaa
    29641 aagactatca agaggatgcc aagatggaga atccaattaa agaagcaatc actaaatatt
    29701 tggaaatgga aatcccgtat aaatgggaag aagctccagc gtgggcgaga cgttcttatt
    29761 atcagaacta tcctgacagt aaatgtaatg agaaaaattt acagcatttc tataatggag
    29821 ctactatgca acaagagttt tatttagttg atagcgtact caccgctgat attttggaag
    29881 ctgtttttga taaacaagca aaggatttat tgaatggtcg atcagatgca gaaactaaaa
    29941 agattgcctt gattattagc agtattcctg gttgggaacg gaagcaactg ccaaaaagaa
    30001 ataaacgacg aggattttac aataagtcaa atgcctatga aaataaaaat cgagctggaa
    30061 agtacaaaaa gtaacgggta gtaacgggtc agtaacacct agcccgttac tagtttaccc
    30121 ttactgcccc aagggataca gcaatttggt aacggggtaa caccttattt ccttaaaact
    30181 tttgaaatag ttagctaata tgctggggaa taatgttact ggattttacc cgttacctgt
    30241 taccaaaacg ctagaaccct tgtccccgtt gggattgagt ggtaacgggt acctgttacg
    30301 taggtgttac cacgtgttac gaatcaagga ggaaagtaaa tgctcaatat tatttcaaca
    30361 aacaaagcac cgaactttca atatacagat gaaatggatc ggtttctaat gaacacgctg
    30421 gcatttagtg tgggattggt aacagaagat tattccacat ttgatccaga agtattaaag
    30481 ataatggaag aagaacctga ttggctgcag gagtcagtag cgtggtgtca atcgctagta
    30541 gtgggatcat tggtagatag tggcaactat gatgatacag gtgagctaat ggatgaattt
    30601 aattgtctgc ttaacctata tgatcgagcg agacaacgag agcttacatc gaatgaggat
    30661 aatttgtttt taaacatcca tgataagttc ttggctttgc tactaacaga tgatgaattg
    30721 ataactaatt tattggaggt agaataatta tgcatatgga aagtattaga tacttcgatg
    30781 gtgagaaaca cattgagtat tcaaacactc aagaagatgt agactttatt agttttgagg
    30841 aagataaaat cactaaagtt aattttaaag acggaacgtg cttgaagata gtttcgcctt
    30901 atattgaata caaatcaaaa tgggaacaag atgattctga cgaacgagat cgctttggtt
    30961 ggtaatctat ggcagttaaa aaacaatgta atcatgctgg atgtaaaaca ttgattgatt
    31021 ataggcagaa gtattgtggg aagcataaag caaagcaaac ggcaattaag cgtgaagaaa
    31081 gaaagcaaag cgaaggtaaa tattttcaat tctatcaaag tagaacatgg cgaaaggctt
    31141 catacttgta tcggttaaat catccagtat gtgaggattg cctagaagaa ggcttgataa
    31201 ggaaagctga tgttgtagat cacaaaattg aactaaaaga tgattggaat agacggttag
    31261 atgaaactaa ttttcgttct ttatgccatg cacaccataa ttccaagaca gccaatgaaa
    31321 gacaaagacg agaaaagagt accctttgag ttaagggggc atagtgtgaa acttactgac
    31381 aatcgatgcc tactcatttt ggtacaaata accgttgtga aaaggcataa gggtaattac
    31441 aaataacgat tacacttgta atcacaagtg aaaaagtata taatgaaagt aggagattta
    31501 ttgaaaaata caattgttat tactgataaa acagggaaac agcgcaccat tgagttacct
    31561 cattttggtc aagtgaccat tcaaatgcag aacggaaaaa tcatttatat agataaatta
    31621 gataaagaaa aattctgatc gaaaaacgaa ggaatgtgag cttaattgct tacgttcctt
    31681 tttcttttgt ctgaaaggag gacaacatgg gacaccctaa aatattacac gatacaaaag
    31741 gcaatatatc aagtgaagaa aaagcaatcc gtgtggacgc tagagaagaa ttgttcaagc
    31801 agcaaccatt aataaatatc acgccccctg actggatggc agcgagcgct agaagtgaat
    31861 ggaatcgtat cgtaccaaca ttaaaaaaag attatccatt gagtgaagca gattatggtt
    31921 cattggtagc ctattgttta gcctttgctc gaatgaaaac agccgaagcc gagataagaa
    31981 aatcaggtac gtttatcaca tgcgaaaacg gagtaaagaa agccaatcca gcggttcggg
    32041 ttcaatcaca agctatgagt gatttgaaaa aacaagccac ctcactaggt atgaccttag
    32101 aatcacgatc aaaactagct ttgaacaagg ttaaaaatga tgaacccgaa gacccgttca
    32161 aagagttgat gaattcatga atgattacat tgagaaagtc ctatcaggta agctgattgc
    32221 acccaagaaa attatccaag cgtgtgagcg tcatataagc gatttggagc gttctaagtc
    32281 agatagcttc ccttatgtgt tcgatgaaga acaagccacc aaagcgatta aattcattga
    32341 gttgctacca tctacggacg gtaaagcaat caagatgtta ggatttcaaa aattcattct
    32401 aggcagtctt tatggctggc gtactaaaga agggaattac aggcgattca atcgagcgtt
    32461 taccagtatg agccgtaaga atgggaaaac gtatatcgca agtggcatgg ctgccaatgc
    32521 gttgattatg gaacaagaac cagcagaagc aaggcaagta ttgtttgtaa gtaacgcttt
    32581 gaaacaagct aaattgggct atgatatgct gtctaattca cttagaaacg tggtcaagtc
    32641 tagtaagttt ttaagaccac aactgaaaat tatgaactct aagattcagc acttgccctc
    32701 taattcgttc gctatggcac tggctagtga aaccagcacg ctagatgggt ttgcaccaac
    32761 aaccgcaatt cttgacgagt ggcacgaagc aaaaactcgt aaaacgtaca acgtcattaa
    32821 gtcaggaatg acccaacaaa agaacggctt attgtgtgtt attagtaccg ctgggcttga
    32881 tttaaacgtt cctatgtacg aggaatactt attgttagat cgtgtgctaa aaggcgaaga
    32941 acaagccgac aggtacttta tagcgatatg ggaattggac gatcccgaag aaattcacga
    33001 tcaagagaaa tggatcaaag ccaatccgat ttttgaaagt gaagaaatca aaaaagtaat
    33061 gattccaacc attcaagatg atgtgaacct tgctttgaaa caaaataacc ttaattctgt
    33121 attggtgaaa aacttcaatt tatggagaca agcgagtgag gacagctata tgattgctga
    33181 agactggcag gcaaccgaag tagaaccaca agatattaca ggcaagcccg tttatatcgg
    33241 agtggattta tctaaaacag atgatttaac tagcgtttca tggatcgtac cgctagataa
    33301 cggcgaactt tattgtgatt cacatagctt tgtagccacc aaatatgggc ttcaagacaa
    33361 agaaaagcgc gacggtttgc cttatcgaga actagaaaaa gctggtgagt gttccattac
    33421 tcaattagaa agtggaatcg tggactatga ccaagtattt cagtttattc aagatttgat
    33481 tcaagaaaat gatttggaat gtatggggat ttgttatgac ccgtataacg ctaattcgct
    33541 tatcagtaaa gctgaaaaag ccaactaccc aatgttagaa gtaagacaag gaacgattac
    33601 tctaaacgtt ccgacccgaa cttttagaga acaagtttat gaaggcaacg ttattcacaa
    33661 taaaaatacg attctcaccc atgcagtgaa caacgctatt ttaaaaacgg ataacaacgg
    33721 cattcagatt aataaatcaa agaacagtaa caaaattgat ccaatagctg cattaatcaa
    33781 tgcctatgtg tttgcaatgg attacttcac cacaacggaa ggagcgaaag cagacaatga
    33841 attttataca agtgaagaat tttctttcta attacattca taccgttctt ttacttcttg
    33901 gattggtgtg tgtgttggtt gctatcacct tactaacaaa tgtctactat ggcttgttag
    33961 cgctgggcat agtgcttatt ggggtagcgg tcatgctaaa tacagaacag aagggaggtt
    34021 aaaagatggc attttttaaa gcgagacaaa atacaacggg agatcctttc ctacaacatg
    34081 tggtatcaat ccaatcggat gattacacca ccagctttac aagcgttcgt gcattaagaa
    34141 atagtgatgt gtttgcagcc gttcgaatta ttgctagtga tattgcttca agtccgattc
    34201 aattggtcaa aaacaatatg ccacaagctg ataatgaact ggtgaagtta ctaaacgaga
    34261 aacctaattc agaaatggat ggttggcatt taaagtttgc tttggcggtc aatatgttgc
    34321 taaacggtaa tagctttgca gagattaaac gcaacggtga aaaggtagaa gaaattcact
    34381 tattacctaa ctcaagtgta acggttactc aattagataa tggtacgttg tcttatcaga
    34441 ttggtgataa aaaaagacgt gtgaagtcta gcgatatttt gcacttcaaa tatttcaccc
    34501 aagatggttt aacaggatta ccgccacttt atgcgttacg tgatgaactg aaaattcaac
    34561 aagctggcaa ccgcacattg cacaatttct ttactcgtgg tgtcagtggg tcaggtattt
    34621 tgaaggttca taagtcagat ttagacggat cagcaaagaa cgcaattcgt gaaaagtttg
    34681 aagaagccaa cggttcaagt agtggagata atgctcttag aacgatcatt cttgatgaaa
    34741 caatggacta caaaacatta gaaataaaca ccgatgtttt gaagcttatc aattccaatg
    34801 attggaacac aaaacaaatt gccaaggcgt ttggtgtacc gattgagcgt ttaggcgttg
    34861 aaaatgaaca ttctagcacc gttcaaagta atctccagta tatccaaagt acgctgattc
    34921 attactttaa tgtgtttgtg agtgaattag atacgaaact tgaaaccaat atccgcttta
    34981 attccgatca gttactagag actgatcctg aaacaaaagt aaaaaatgta ttggatcagg
    35041 tcaaagggtc acttctcacg attaatgagg ggcggtcgaa aatggggcta ccccccatgg
    35101 atggtggcga tcgtttacta gcaagtttga actttacgta tttagatacg ttggagaaat
    35161 atcaattaaa agaacaggaa ggagttacac cagttgaata atgaagaaga aaaggaaaaa
    35221 cggctgacag aagaagctga gctaacagcc gattctccca aagtagagaa agaaaatgaa
    35281 aaacaaccaa cagacggcaa aactatttca ggctatgcgt tgaaattcgg gcaaccgtca
    35341 aaagatttag gcggctttgt agaagtgatt acacccgaag cattaaaaga ggtggattta
    35401 tcaaatgtgt tcttattata tggacacgat tattcaaagc cactagctag tgtcaaagca
    35461 ggtacgttga aattgaatgt cgatgataca ggattacatt ttgaagcaga gctaaccgac
    35521 acgacctatt caaatgatgt gtatgagaat atctcaaaag gggttgttga ttctatgtcc
    35581 tttgggttcg tgcttggatt agattcattc gacaaaaaag aagatggcac aattgaacga
    35641 tcaatagata aaatcaaagc acttaatgaa attagtgtcg tgaccgttcc cgcttatgat
    35701 tcatcaaatg tccaagtaaa taagcgttct tacgaatcgt ttatgagtaa caaccaagca
    35761 aaacaaacaa acaatagctt agaatccact tctaaagcac aaaaggagag taataacatg
    35821 gaaaaaactt taatcgataa cgaaaaaaca gaattgcgtg ggtatgaaga atatatccgt
    35881 tcacaaggcg aagtgcgtga tggagtcact actgtaaatg cagcggcagt tgttcccgaa
    35941 gaagtaatcg gtgaagtctt tgatttgaaa cgttcaaatt ataacttagc tcaatatgca
    36001 acagtaaaaa cagtatcaaa tggacaaggt aaatatccag tagcaactaa ccaacaagca
    36061 gtgttagcaa caaaagctga acttgctgaa attggtgata ttgacgctga aatgtttact
    36121 tcagttgatt ataaagtaga aactcgtgct ggtaagattg ccttatcaaa tgaggttgtg
    36181 gaagattcag cagtgaatat tgtacaagag gtcaaagatc agttagcgaa attggtagaa
    36241 aacactgaca ataagcatat catggattta ttaaaaacat tcactaagaa aacggctgct
    36301 acgttggacg atttgaaaca actatacaat gtggcattag acccagcatt aaataaaatg
    36361 gtaattctaa accaaagcgg atattaccac ctagatacat tgaaagattc agatggacgt
    36421 tacattttac aacccgatgt gacagcacct agtggtaaat cattattcgg tatgccagta
    36481 gtattgattg cagatacatt gtttgccaat cctaaagctg gaacattccc tatgattatg
    36541 ggggatattg cacaatctat ctttgttgct cgtagaaatc aagtaacgac tcaatgggaa
    36601 aaattcgatt actactcaca aggacttgca gtgatcgttc gcaacgatta taagaaaatt
    36661 gatcaaaatg cttcagtgta tattgagttt acgccagttg taacaccaaa agtatagaaa
    36721 aatattgggc ggcggtttat cccactgcct ttttttcatt aggagagata aaatggtaat
    36781 tttggatagc ataaaaaaaa gtatgcggat cgatcacact attgatgatg actttattca
    36841 acaattgatt gatacagcag gcgaatatat aaaaagtgct attgatagta gcgcaacgga
    36901 taaagatatg gataattatc agcaatttga tttggcggtg tcattactta ctcaacattg
    36961 gtatttgaac cgtcaagaag ccagcagcga acggatacca gtaacggtac aagcattagt
    37021 acaacaaatg agaggtgctt attatgccaa tcattaagaa tgtaaatgaa ttgactgaga
    37081 gagtcaagtt taaaaagaca aaacgggtaa aagatgaaga tgggcagatg gtggatagtg
    37141 aagaaactgt atttgaatgt tgggctaatg tgcgttcaca aatgctaaaa gacgtgcttg
    37201 ctagtgtagg taccattctt gaaggaacgt tgacgtttat tattcgatac gatcaagatt
    37261 atgaactaac aaacgatatg aaagtagctt ggaaaaacaa gagttataaa attatttcaa
    37321 tcaatgaagg aacggcgttt aaagattata caacgatcat agctaaacag atttcttaga
    37381 atgattacac ttgtaaacgt tgtgggtatt tagtataatt aaggtagtaa atgaagggtt
    37441 agctgcctga attttgcaag acttagctag tcgaaatcta ttgttggact gaaaattgta
    37501 ggtgtggttg caaacatgct ggactaagaa agatgataga tgatgaacgt tcaattttaa
    37561 tacaggcatg ctaggactga ttggatggtt ttggcaagct gattgtgtag aaatcaaaga
    37621 acacgtctgt tgtggacgtg ttttttttgt tataattcaa aagaggtgat ttaatggaca
    37681 aagcagagtt tacaaatttt tattggaagt attatctaca tttagaaaat gagtttatta
    37741 ataccacaga ttttgtgatg ctcgatgaga ataatttcaa aacattctct attgaatatc
    37801 aaaaactact actagcgatt ggttcggagt gtgagattat tttcaaagaa ctttgcggat
    37861 ttgatagcag tagcaataaa agcataactg attttaaagc tgttattaaa tctagcgaat
    37921 taatgtgttt ggataatggt gttagggtta tgaattcttt aacattgact tcactaaaac
    37981 cttttggaga tgggtggcct gaagatacac cagattggtg gaaaatatat aacagagtaa
    38041 aacatggtcg ttcttcaaat tataaggaag caaatttgga aaatgtgttg tatgctttag
    38101 caagtctata tttattagag gaatatttgc ataagaaagt aatactagaa ggtgaagtag
    38161 actttataag tccagagtca aatctattta cgttatcttg ggaaagaaaa cattcgtcga
    38221 tgcaaaaagt gacgtttgaa aaagtggatt caaattatgt agctccactc attgatttta
    38281 aagaacaaga agaaatttaa aaacccccac ggcttattga agtttttgta tgccatattg
    38341 tatgccattt ggtttaaatc gcttgaaaaa tagtgataga taactctaat tcatttagtc
    38401 ataaacgctg ttttgataac ctttatagtt ctttgatatg ggtttctcat tcatggcgga
    38461 agaagaagaa tagaacaaaa gaatgaatta ataagatata aaaaaaggga ttgtgacaaa
    38521 cgtcttgtca caatcccttt ttccaaataa acgatgttca atcagctgcc cctcggcatt
    38581 cgctcgaaaa acggcgaaat atgaagaact attttgccat ttgtttctct aataatcagg
    38641 tcaaaacgtt gacttcacag tctcttcctt aaacggtgtt ctcctgccaa ctcctcggtc
    38701 acaagtcaca atattcaaca aacatgagaa gctgtttttt gaaattgttc cttgtgactc
    38761 ggagctgaac ggcaggctca cgacctcttt cttaaacggt gttcaaaagc ttgcatctgc
    38821 ggtaataagt tcaaccaaac gaaaattatg aggagctatt tttgtttggc tgttcttatt
    38881 acttgatgca ggacagcttt ttcacaacct cttttcgttt agcactaaat ttccttaaaa
    38941 agtagaaaag ctttcgaagc ctcgtttgtt tcttttactg tataataaaa gaaaagagta
    39001 acaatcgcta aaagatataa acaagagaaa ggaaatacaa gatgattggt ctgatttatt
    39061 ttgtggtgat cgttctggcg aacacagttg gcgctatttc cgggatgggt ggaggcgtgt
    39121 tgatcaaacc gattcttgat cttatcggcg cccattctgt tgcagggatt tctttttact
    39181 caacagttgc ggtattcacg atgtccattg tttcgactgt gcgacaagta tcaagcggga
    39241 aatcactgaa ttggcagatt gtcggttggg tatctagtgg agctgttgtt ggaggagtag
    39301 tcggcaacat tgtattcgaa gtttttttac agttatttga aaacgagaag catgtgcagc
    39361 tgatccaaat ttttttgacg gtattgacct tggtttttgc gttcttctac accaagcatc
    39421 atcagccaaa atttcatttg acgtcatgga cttggtacct tatatgtggg ggggttctgg
    39481 gctttttagc tagtttttta ggtattggtg gtggaccagt caatgtttct ttgttgatgc
    39541 tgatgtttgc attgccaata aaagaagcaa cactatattc tctatctacg attttctttt
    39601 ctcaactggc aaaattggta acgattgctt taacaagtag ctttatgcgc tttgatttat
    39661 ctatgttgtt ttatgttatc cccgctgctg ttattggagg tttgtgggga gcaagattta
    39721 gcagggtttt gtctccaaaa aaagtgacct ttatttttca agtaattgtc ctcgtggttc
    39781 ttttgatcaa tctttacaat gctttcgtca tcttacaaac attaggagaa tctagactaa
    39841 cgcaagtcaa aatcactgaa acatattgtt ctaaatgaaa aaaggagtat actgtgataa
    39901 aaaaattcat ttaaaaaaat aaaaattggc tggtgatttg gatgttgcgg gaaatgcgtt
    39961 taggagatgc agaagcacta cgagaaatca atgcggaaca attaggatat gatgtaccat
    40021 taaccgttac ggtgagacaa atgaagaaac tgttgaagga gccagaaaaa aattttttct
    40081 tggtctatga agatcctact tctaaaaaag cagctggcta tgtacaagcg gagtcctatg
    40141 aatcgatttt cagcgatccg atgttcaata ttatggcact tgctgtgtct aaacatgctg
    40201 aaaaaagagg aatcggaaag gccttgatga ctggcgtaga agaagcgaaa agacgaggaa
    40261 tatcagcaat aagacttaat tctgcagaat acagagtaga agcacaccga ttttatgaac
    40321 gcatcggtta tcattccgat aaaatgcaaa aaagattttt gaaaatcctg taaattttta
    40381 tcaaaaaata cctggtcatc aagccgatac ttgatgatca ggtatttttt ttgactaaga
    40441 aagtaattgc atcaagaaac ctgagatgat caaaacgatg gcaccaccaa gccgattgcc
    40501 catttgagca aaagcaataa gttccatccg attagctgca gataagacag ctacatttcc
    40561 tgtaccaccc atcgagttgt tgcataagcc agcagtaata gttgattcga ttggatataa
    40621 accaaacaaa cgaccgacaa atcctgaaac tactgaaatc gcgataacac ttgtcaaaca
    40681 taagacaaca aattgccatg tcaaagcaga agccaataca tttagattca ataacgcaat
    40741 accgataccg gcaagaacag ctgctgtcaa gtttttgaca atcaagttgt tgaacatgat
    40801 agctgcatct tcgtaatatt ctggtaatag gtttgcgatt ttacagataa caacgataat
    40861 gatcatgaat gcgtaagcat ggactttagg aacaaaatag ttacagattt gtcctaagat
    40921 gaagaaagtc aatgatacca tcaaaccgac acctaattgt ggaatggaag gttttacatt
    40981 tctaggtttt ccatcgccaa ggtcgccttt ttccattaat ttaccattac cgttgaattt
    41041 tggcattgat tgtcccgcac gagcaactaa cgctgcacca atgatagcta ggacatttgt
    41101 cattgctgtc gcaggaatca ggcgggaaat gatagaagaa gcgtccgtac ctaaaacatt
    41161 tgcataaatc gttgataaag gtacagctcc ggctccaaca ccaccagcca ttgcgggcaa
    41221 tgagatatat aaaacggaat ttgcaaaacc atttccgata agcataccta cgagtcctac
    41281 ggcaaaaaag gagacgacca ttgaaataag tgcaacggga ataaaacgaa cagaagcttt
    41341 catcaataga ttacggttca taccaaggat gctaccagta atcaaggcag caatataaaa
    41401 gtctaaaaag cccatattgc tgacaaagtt ttctgtggat tttactacat actcaggtaa
    41461 gatcccaaat gtagcaatcg cggcagaggc aaagatcgca aaaacggagc caccacctaa
    41521 ataacttttg acgataggga tttttgttcc gataaaatga aataaattac cgaaaatgac
    41581 caaaacagcg attgggccaa tcatattcgt cggtaatttt cctaaagcca ttgcaatgat
    41641 caggacaagg accatgatca aataaagggg caaacttacg ccggtaattt ttgttgacca
    41701 aaacccttct tttttctttt cctcaactgc agttgcggtt gttgtttttt gtgccatttt
    41761 tacagatcct ttcttattct gtatcgtatg aaaaaagcca aagagaagcg gcaaaagagc
    41821 agtagttggc tggctgctgt tttgccgcag tcgctttttt ctttttagac gtcatacaaa
    41881 gtttctgtat gttcttttac tataacaatc ttaatcttct aaagatttat attcaggaac
    41941 ccatttagca gattcaacag cttctttgat atccgtgatt tcttcacgat tcaatttttg
    42001 tgcaacaact gattttgcga cagtttcagc aatcgtttga gagaattcag tgatttttgc
    42061 tactggaggc aagatagctg ctcctggttt tgttacatca acgattccgc ctaatgctcg
    42121 actagcttga gaaatgattt cagcatttac tcgtgtagct gttgaagcaa tcaaaccaag
    42181 ccctaaacct gggtacatca acgcattatt tgcttgaccg atttggtaag ttacaccgtt
    42241 atattccaca tcagcagcag ggatacctgt tccaactaaa gcttttccgt ccgtccattc
    42301 aatcaaatct tttgcttttg cttctgccaa ttttgttgga ttagacaaag gcatgatgat
    42361 tggacgtggg gtatgagccg ccatttcttt cacgatttct tcagtgaatg ctccaggttg
    42421 ggtagaagta ccgatcatga tcgttggatg gattgctttt acaactgctt ctaagtttgt
    42481 caattcatca gcattagtga attctgagcg tttacgagcg aatgggattt gaccaggagt
    42541 caatcctttt gtatcttcaa acaataaacc ctgtttatct acttgataga aatgttggcg
    42601 tgcttcttct tcaggtacac cttgacggat catttcatct aaaaggatgt ttgcgatacc
    42661 tacaccagca gtaccagcac caaatgtcaa gatcgtttga tctttcaatt gctcacctga
    42721 tatattcaat ccacctaata caccagctag tacaacgatt cctgtgcctt ggatatcatc
    42781 attgaaagta gtgattttat cttcgtattt ttctaagatc gttgcagcat ttcctcgtcc
    42841 aaaatcttcc caatgtaata acaattctgg gaataattca gtagctgatt gaacgaattg
    42901 atcaatgaat tcgtagtaag tttcgccttc tacacgagca tgacgattcc ctaagtataa
    42961 tggattattc aataattctt cgttattagt accagcgtcg attgatacag gcaagacttg
    43021 tgcaggattg ataccagccg cagcagtgta gaccatcaat ttaccgatag cgatgtcaac
    43081 accgttcaca ccccagtcac ccatacctaa gattccttct gcatctgtca caacgatcaa
    43141 acgaatgtcg cgtccatctg ctgcgttttt caaacttgct ttgatatttt ctggttcgtc
    43201 gattgaaaga aatgcagcat cttgtggttt caagaaaatt tcgttgtatt gttcgattga
    43261 atccgcaacg acaggatcat aaacgacagg catgaattca actaaatgtt cgcccatcaa
    43321 tttataaaac aatgtccggt tcgtattgaa tagattcatt aagaagatac gtttttccaa
    43381 atcggtctgt ttgcttaagt attgaccgta agcttggaca gattgttgtt ccaatgtttg
    43441 gacagtactt ggaagcatac cagtgattcc gtattttgcc cgttcttctt ttgtaaaagc
    43501 tgttccttta tttagaaaag gattatttaa taagtttagc cctgtaagca tgaatgattc
    43561 ctcctaagtt ttaatacaaa cgaagtatag gagtcagatg aggatatagt caaaaagagc
    43621 aggtataata aattttattt atatgagtaa tagagtcaaa agaaatcaaa atagcggtat
    43681 ttgttctttt tatatcaaca atccttgctt gattactatg cgtatctctt atatgctaaa
    43741 gaaagaaaag tagaagaata aaggatatgt tagatagata aatagaatct ctgaagaata
    43801 aatcacgtga tcgtgacgat aaaatacact tacgtcaggt gataaaaaat acataagtag
    43861 aaaactaaga ggaggaacag aaaatgaaag aagttcaatt gatcagaaaa agcgaactat
    43921 cagaaggtgg ttgcaatgca tgcggcgtag tagaagcaac aagctataca ttaaagcttg
    43981 gtgccaacaa agcgataatc tctgagttga cagtaggcgg tcttgtggac agtctggcgc
    44041 ttgctgaagg ttttattgga gaagatattt atgagatgtt ttcagaaatc cgtcagttaa
    44101 aaaaagggga aaactgcata gaggttcatc atgagagccc gaatgtgaga ttcaaacgtg
    44161 gtgataatga gatgatcttc aataatcatg tgtccgatca caccgagcta tatggaatcg
    44221 tgaatcaaat actaactgag ctttttggat tgggacctta tgcgttcaag gaagaaaacg
    44281 gtaatccaaa attaaacgaa gaatggcaag aaacgattga aatacaaaga aacaacccgc
    44341 acttatttca ataggcatcc acagtatttc gtaaaaggga ctttgacacg acttttgtca
    44401 aagtcccatc gttttttatc tatttgtgtt ctaaacattt ctttcagagt agtaacaact
    44461 ggaatgactg aaatgtaaac agattatttg cctgtatcaa tacggaagag taatataaag
    44521 tgtgtaaacg ctatcatatt attcattcaa ttttttatag agggaaggca ttgaaatgga
    44581 aaaaacgtat caagcaggta caaatgaagg aatagtggat tttatcaata tggaagattt
    44641 agaaatagcc gcttcacaag tgattccagc tggtggttat ggttacatca gcagtggtgc
    44701 tggcgactta tttacttatc aagaaaatga acgggcattc aatcatcagc tgattattcc
    44761 tcatgtatta aaagatgtag aattacccga tacaactaca cattttgaca aagaaacgct
    44821 gactgcacca atcatcatgg caccagttgc tgctcatggc ttagctcatg tgaaggcgga
    44881 gaaagcttct gcaaaaggtg tagcagattt tgggacgatc tatacagcaa gttcttacgc
    44941 ttcttgtaca ttagaagaga taagagaagc aggcggggag aaagcaccgc aatggtttca
    45001 attttatatg agcaaagatg atgggatcaa tttggatatt cttgaagtgg ccaagcgtaa
    45061 tggagcaaaa gcaatcgtat tgacagcgga tgcaacagtt ggcggaaacc gtgaaacaga
    45121 ccgcagaaat gggtttacct tcccactgcc aatgccgatc gttcaggctt atcaatcagg
    45181 agtaggccaa acgatggatg ctgtgtacaa atcttccaaa cagaagctta gtccaaaaga
    45241 tgtagaattt attgctgctc attctgattt gccagtctat gtgaaaggtg tccagtcaga
    45301 agaagatgtc tatcgttcat tagaatctgg tgctggcgga atctgggtat ctaatcatgg
    45361 tggccgtcaa ctagatggtg gtccagcagc gtttgattcg ttgcaatatg tggcagaagc
    45421 agtagataaa cgtgtaccaa tcgtgtttga cagcggtgta cgacgcggac agcatgtttt
    45481 caaagcaatc gcatcaggtg cagatcttgt tgctattggc agacccgtta tttatggatt
    45541 gtctttagga ggaagtacag gagtccatca agtgtttgat ttctttaaaa cagaattgga
    45601 aatggtcatg caattagctg gaacacaaac agtagaagat atcaaaaaaa taaaattgcg
    45661 tgagaatcgt tttatttaag aaacaaatga cgaaaaaaat aggagtgcgg cagatgatgc
    45721 cgtactccta tttttatagt tcaaggatgt cactaataga ataatttgaa acgaaaaaat
    45781 aaaattgaaa tattttttca tacttaataa aaaaggaaga atattcatgt aaacgatttt
    45841 attgtttttt tctcttttat acaaaaaggg tcataatttc aagtaagcgg atgaattcat
    45901 gaggattttt tgcatactgt ctctactata cttaggtcac taagaaaaag gagtgattta
    45961 ttatgaaaaa gaacatgatt gggacattat tactttcaac acttcttcta ggcggcttgg
    46021 caacaccagc ttttgctgag ggtcaagcga cttcaaaagg agatattacc tttactgaac
    46081 caacaaatac cgtggagcct cttaacccta ctgatccttc aaaaccagta gagccagcag
    46141 atccggaaaa tccagcaact ggccagacag gtcctttaac actggatgta gttcccgaat
    46201 tgccatttgg tacacacgag attgaaagcg gaacaaaaac gtatcaagta gacgcttcaa
    46261 aaaacgatac accttatctc caagtatcag atcgtcgagg tgtaggtgca gatggccaag
    46321 cacaagggtg gaacgtgaca gtttcggttt cagattttgt aaacggttca caagttttgc
    46381 aaggcgctga attagatttt ggaacatcca ctgttaaaag tacgtcagat aacgaatcca
    46441 ctggaccaac tagtcaaact gtaactgggt tgagtaaagc aagtgcagcg acaccaatat
    46501 ttacagcagc aaaagatcaa ggtctgggaa catggctttc tgtttatgat ccagcaaata
    46561 tcacactgaa agtgccgaaa gcagcagctg gaacattcac ggctgatttg acttggaacc
    46621 tcgtggctgg cccagtagca tagagtatga aataaattca acaaactgcg gtgaaaatac
    46681 tataggtgaa ggatttttta ccgcagtttt tgttgaaagg atgtggtgga caatgaatca
    46741 aagtaaacga ctgtttgttt cgtttttttc tattttaagt ctatttttca tttttccgtc
    46801 aatcagccaa gcaaaggatt cagcaggaga ctttggaatc aaaccggtat ttccagagaa
    46861 ccaaatagat aaagcaatcg gttattttga tttattagtg gcaccggaac aaaatcagac
    46921 actagaagta attatcagca attcttcaga tgaagaacga acatttgagg tctctgtcaa
    46981 tccggcggta acgagtgatg gtggaacgat cgattatagt caaaaaaacc caacgttaga
    47041 tgagacattg ccgtttgatg tccgtgacgt tttgctcatt gcgaaaaagg aaatcaatgt
    47101 atcagcacat gcagaaacaa ctgtacctat agaagtgaaa atcccagcaa aaagctttaa
    47161 gggacgtgta ttagcgggta ttcatgtttc acctaaagaa gaagctgaaa cagaaaatgc
    47221 tacagaagga gcacaaatca aaaatcgtat tgcttataat ctcgcagtcg ttttacaaga
    47281 aagtcaagag acgatagaac cggatctgaa acttttatca ggagatttgg acgaggtcaa
    47341 cgcaaagcca actgttcagc ttcgtttcca aaatcctcag cctaggatta tcagcaattt
    47401 gatatttacg agcaagatct tttatgaaaa tcagctttat attgaaaata cgtctaatgc
    47461 atttttagtt gcaccaaatt cgaattttca cttgaatctt gatttagctg gtgataaagc
    47521 aaaagccggc gattaccgcg cagaaatcat agcaaaatca ggcgacagta atgaatggcg
    47581 atttacacaa aactttacga tcaaaaaaga aaaagcacaa aaagtaaatg aaaattccgt
    47641 ttttgcagta caagaacaat ctttcccatg gctttatgca ggattggttg ctgcagttct
    47701 agtgttatgg ttgattttgc tgtttttgtg ggtccacaag aaaaagaaaa aaggagaaac
    47761 aacatgatga ggtgatttcg ttgaaaacat cgatcttatt gggagggatt attgcaagtt
    47821 tgctgttctt cagctggcaa gagccagtcc aagcagatac caaaagttca ggtacgatta
    47881 cattttatga tctaagtcca attccgcatc caagtggttc agtcaatggc gcatcaaaac
    47941 agcagacaca gctaccgatt tataaagaat ctaatcaaca tggcgtattc ccggagacga
    48001 atgaacaaaa gatccgtttt ctttatttga tcattggtat agaattatgg cttcttgcgt
    48061 ggttgttgtt atggagaaga aaggaaaagg aggatgaaca tgttgctaca aaataaattt
    48121 tcattttttc gctccttctt ttttacttcg ctttttgttt taagtatatt tatcttttca
    48181 ccttcggcag aagctgttgg agcaacgcct cctgccattt cttatgatcc atacacgtat
    48241 gaaaatatcg tacctccaaa tggtggacgt agtgcagtca atggcgggaa gcttgtccaa
    48301 ctaactgggg ctaaccaatt gcctaaattg actgctactt atttgaacga tggttcaaat
    48361 gatccttgga aaggtggcac ggtccgtttt cattgggaaa gccatgtgaa actaacaaat
    48421 gtacttgatt tggtgaatat cactgcacaa ggatttgcat ttgtggcgat catcaatttg
    48481 ccggaacatg tatcaagcag tgatgtatta aaagcaattg actggaacaa cgcctacttg
    48541 tatattgccg gtgcccccat caaggttact agcggaagtt tattatcagc aggaagccat
    48601 accttgcgtt ttgggatggg gtcgtgggat acaaatactc tattgacaga tattattgct
    48661 attattacgc gaggcgaatt caacgtggac gatatcccgc ttcaatttga tgttacagct
    48721 aatgtcgcga agatgacaga aaacggagat aaatatgata cgagtccaaa caaaattttg
    48781 accaagggta aattacaacc ttctatgtct aaaaaggccg ttttttctgt tgatttttat
    48841 gattcgaata atattatcca agatcgtatg ttcaattcga ttttagctcc agctgcaggt
    48901 agattttatc ctaaattaac tggcggaaac ttgaatccag gagcatatgc attttctgca
    48961 agtgcagaga taaatacgtg gaatagttac atctcaccaa gtgattcaac aggaaaatat
    49021 aatacatttg ctgataccac agaatacgtg gatggaaata accagaacct tccaggctct
    49081 accaatagtc ggacattgac gatggggctg actgaaggac gttttgatca gttgccattt
    49141 agtcgctttg atcgcgtagt caactatttt acaggaaaaa acgttacaca aggagcaata
    49201 ctgactcata ctccagcaag cacaagtgga ttgaatcaga cagccaatat cgtgtacagt
    49261 gggaaagatg cgcaaggcgg attgctttct cctgttgctt taaaggtatt ggagcagtac
    49321 aagctagacg gaacggtttt accaacaaac ttaacagccg atagtcagtg gggaaagctc
    49381 ctttcttctg catcgtacca agtcacggcc aattggtcag caactgaact aaaaaagggt
    49441 tcgatccatt acaggcttta ttcgaaagga acccaaaaat tagcgacagg atggacagat
    49501 caacttttcc aaacgatcca atcaaataac gggggtgtaa atacagctac ttctacacta
    49561 cctgcattgg cttcagggca atattatttt gattatcgct tggtggacga tgtacttact
    49621 aacatgtatc cgtcttttgc gtacaaatgg cagtctgaac aagctggaat caccactctt
    49681 cctcaaataa cagtggctaa ttttccatct gtgagtgcag atagtcagct aaaaaacctt
    49741 agcagacaac ctgagacagg agatcccctg tctgctctat caggagatac gattcaagaa
    49801 aatgtgacat tcacgttaac aaaatctggg gatgcgataa ccgacaaaaa aatcacgatc
    49861 tcacttcctg aaaatactac ttatatcaat ggttccttaa aattaaatgg tacaactatc
    49921 gcagataccg gcattcaaca aggagtttct gtcccagcag atctattgag caaaatagga
    49981 gataccattc atcttactta caactatcaa ttaaatactg tagatacttc tttacaatcc
    50041 gtcagcatac tgacaaaggc agctgtactt tccagcaata ttacattagc agatggtgct
    50101 aagcttccta acccagttgt ccaaacatct gctaaaacaa ttcttgtccc caaacaagaa
    50161 ttaacattag ttaatgtacc agatgatttt acatttggta acgatctccc caaaccgttg
    50221 aagacaagtt attatgaatc aaaaggcgat ttttcttttg atgtgcggga tactcggctt
    50281 ccaagcacgt ctccttggca actgacaggt acattgactt ctttatttaa gaatgatcaa
    50341 ggtcaagaat taagcggaac aaaattatac ttcaatcatt ctggatcaaa gcaattgatt
    50401 cagcaaggtc aaaacacgtt gatttatgag agtgatggaa cagctaaagg agaggttctc
    50461 gttgactttc ccgataccga tggtttactc ttagaggtaa atagcagtac gaatgctcaa
    50521 cctggcgcaa cgtatcaagg catggtcaca tggaaactga cagctgggcc aaccagctaa
    50581 gtgattagaa tttgtatgga tctgtgataa ctgtcacaga tcctcttttt caaggatgag
    50641 aaggaaactt ctgctgttaa aatcagaaat gcttgaagga gtggacttgg aacttttcag
    50701 tttgcttgaa aaaaatgaac aacggcaaat caaacttttc caacttttat tagaggaaaa
    50761 aggagaggtt tccgttaata acgtacttac ccgcttatca gttgatcggg ctaccttgaa
    50821 agaagatctg ttttatttac aagctaactt ggaaaatatc aaacaattgg aaattgttat
    50881 ccaagaaggg aatattttat taatcagaca tggaaatata gcagcagtcg atgtttatta
    50941 tcattgttac ttgcgctatt ctacaaaata tcagatactt ctttatctgt tggaaaatgg
    51001 ctcatttgat cggcagaaac ttgtcatgga acttaatatc agttcggcta ctttgtctcg
    51061 cagagtgaag gaattaaatg attctttaaa tgagtttcat ctgaaaataa aaagcgggcg
    51121 gctgaccggt ccagaaagtc aaattcgtta tttttatttc caattatttt ggtttggacg
    51181 tccctatctt gaaaacaaaa aagaatacag tgatttatca ggaaacactt ttttagatct
    51241 gctgcaaaaa gagtttagtt ttgctattac agaagaagga cgattgaaat ttgaaatatg
    51301 gctttccatt atgaagaagc gaatgcgctg tacgaaaaaa tccaaaccag attatagcaa
    51361 tcttcctgtt ggattgtttc aaacgacaca atttttattg gacctccata catttttgac
    51421 ccgttacttc tttcaatatg cctttccttg gaatcaaaat gaaacgttgg ttttttatct
    51481 tttcatgatc agtaacttta cattagatac acataactcg catgtccagg agtttttgat
    51541 aagcgaaaaa tacaaagacg acgtagtagc tcaattgaat cgaacgttta aacaatcgat
    51601 agaagaatat ttctcttttt atgtttttcc agaagagatt tcgcaaaaga ttgcgttgac
    51661 agtgatgcaa aatcacgctc attttgccta ttttagagga tggatgaata tttttggcca
    51721 agaaggatta aaacagcggt taactgaagt agaagataaa caattcctgg ttttatgtga
    51781 aagattggtc agacaaacat ttgctattgt tgattttact gaagtagacg aggaaaatgc
    51841 ccgctttgaa ttatttgctc gctatgcatc tattttacgg acgctgatca agcagttaga
    51901 attacgtctg caaattgctt atgatcttcc ttatgaaagg ctaatggcgg atatcgtgaa
    51961 agaaatcatc caggaacaat tgctgaatac gatcaaatat gatttagtcg aatacgagaa
    52021 agaaaagcag tatgatatca ttttgactag ccaattgaaa gagtacccgt cacagaagtc
    52081 cgctaaagtt tttgtattca ctagcaacga atataattat gatttcccct atttgaacca
    52141 atttttaaaa gaatgttatt tagaaaaatt gaatttaagg atgaataaaa catgaaaatc
    52201 gtgatcattg gtgcttccca tgcaggcatc acagctgccc taaatctaag aaaacttcaa
    52261 ccgaaagcag aagttttact gatcgatgaa gatcataaag atggactagg ctatgtttca
    52321 aatggaatca acctttattt aaaaggaaag atacgtagtt tagctgaagt tgcccataac
    52381 atgcggactc ttcaagaaag tggggcaaaa ctgatcaccg aatggagagt aactgaactt
    52441 gatccagaca aacatcagct catcctcgca tccaaagaag gaaaaaacga gaccataacc
    52501 tatgataaat taatcgtagc gacaggttcc tctcctgtca ccttgtataa acaaattgaa
    52561 gctgaaaatg tctacaccta taaaaatcta gtgcaatcta agcaagtact tgccgcttta
    52621 aaagaagcaa aagaagtagt gatcttcggt gctggttaca ttggattgga attagcagat
    52681 gctttgagaa ataaaggata cattattcat ctagttgatt atatgccgaa tgttttatca
    52741 agatatttcg ataaggatat gatcaacagt tttcaaaatc agctgcaaac taagcaaata
    52801 aatttttatc caaatgaatt cttgatcgat tggaaaaaat cagaagagaa agtagtatcc
    52861 gtacaacttc tgtctcaaac aataaaggca gatatggtca ttttttctgc ccaaactcgt
    52921 cctaatacga cattgttaaa agaaaaagtg gctttgtatg aggatgagac tgtgatagtc
    52981 aatgaatatc tgcagacaag tgatccggac atctatgcga ttggagatat cgtcccagtc
    53041 agttttgaca aaaataaacg gcatctcttt ttacctttag ttactcgagc tgtacatatg
    53101 gcaagagcag tagcgctaac tttgagtggt cagccaaccg cttacgacct cagacaaaag
    53161 ataacagcag cagtcattat agactacttt ttaggaactg tagggctgac agaagatgaa
    53221 gcgccattct tggaacaaaa taccggttcg tgttcaggag aatttgatct atttccacaa
    53281 tacgacgaag aaaacaaaac agtaaatgca aagctgatct accatccgga tacattagaa
    53341 ataattggcg gacagctgat aagccaagaa ttcttattat cagatttgaa cctgcttgcg
    53401 gatatcgtga aacacaaaac tacgattcca cagctagcag ttgaggattt tggatttctg
    53461 tctgaataca cctctcgttt tcactacctc aatgagttag cttttaaagt actagctaag
    53521 agagcaaata gcaatagagt agataaaaga ctgtgagaaa tatcacggtc ttttattgtg
    53581 tggggatata ataaatatta atcaatcgag aataaaaaat tcatataatg aaatagcgga
    53641 agaatttttt gagcataata ttcgccaaaa atttatcaag tgataaaatt gttgtataaa
    53701 atgattattt caggaggagg agttaaatgt ttttagcatt aaatgaaatt atgcattcaa
    53761 agttacgtta tgcgttagtt gcaggggtga tgtttttgat cgcctacctg gtattttttt
    53821 tgactgggtt agcttatggc ttagctcaag ataatcgaac agcagtcgac aagtgggagg
    53881 cagattcgat tgtgctttcg aaagatgcaa attcaaatct agggatgtcc atgattacta
    53941 agaagatagc agaagaagtc gaaggtggga aagtggcgta tcttgcccaa acacctggag
    54001 tcgtgactag taaagacagt acagaagaag gaaaaatcaa tgttagcttc ttcggtatcg
    54061 ataaaaatca attcatcatg cccaatcttg ttgaaggaaa agcttttgat aacgatgatg
    54121 aggcagtagg cgatattagt ttgaaagaag aatatggtct agccatagga gatacagtta
    54181 agttatctgg tagtgacaag acgtttaaac taactggctt tacggatcat gccaaattca
    54241 atgtctcacc agttctctat acaaccatca atgcttacca agaaatccgc ttcgaaaaag
    54301 aagatacaag tgaaaatgca cggattaacg caatagttgt cagaggtaaa atcagtaatt
    54361 tacctgaaga tttagaacag atcaaaattt ctaaattcat caatgaatta cctggatata
    54421 atgcgcaagt attgactttt ggatttatga tcggattttt gatcgttatt gcggctattg
    54481 tgatcgggat tttcatttat gtactgacga tgcaaaagat taatatcttt ggtgtaatga
    54541 aagcacaagg gatcacagga ggatttattg cgcgttctgt agtggcacaa acattcattt
    54601 tatcatttgt tggtattctt cttggtctat taggaacagt gggaacatcc cttgttctac
    54661 ctgatgcggt tccattccaa agcaattggc tgttttttgg cgtcattagc ttgttgatgt
    54721 tagtagtagc tgtgttaggc gcactatttt ctgttcggac aatcgtaaaa atcgatccgt
    54781 tgaaggcaat tggataagaa ggaggaagaa catgaaagca atagaattta aagaagtaga
    54841 aaaaagtttc caagatggcg accaagtagt taaagcattg aaagaaacaa ccatgagtat
    54901 cgataaaggg gaatttgttg caatcatcgg tccttctggt tcaggtaaaa gtactttttt
    54961 gactttggca ggcggattgc agacgcctag cagtggctct gtatttatca atgatcaaga
    55021 attcagtaat caaaaagaaa gcgaacgcgt taaactacgt tttaaagaaa ttggctttat
    55081 tttgcaagct tccaatctgg ttccttttct gacagtaaaa aagcagttat tattagtaga
    55141 taagattaaa catgaacatc gtcaaaaaga agcaaacgaa ttatttgagc agcttggcgt
    55201 ggataagttg atcaacaagt atccagaaga actatctggt ggagaacggc aaagggtcgc
    55261 aatcgctcgt gcattgtaca atgatccgtc cattattcta gcagatgaac caactgctag
    55321 tttggattca gaaaaggcac gagaagtagt cgatatcttg gcaaaagaat caaaagacaa
    55381 aaataaagca acgatcatgg ttactcacga tacacggctg attgacaaat gcgatagaat
    55441 atttatgatg gaagatggtg tattgaaaga aaaagaataa ccaaaaagca ggtggaaaaa
    55501 tggtccatcg atacaacaaa gatacacagc aaaaaatttt gaaagaagcg actgacttgt
    55561 ttatgtccaa gggatatctc ggcacttcaa caagagaaat cgcacaaaaa gttgggatca
    55621 cccagcccaa tctctatcat tatttcggtg ataaagaaaa actatatacg gcagttttag
    55681 aaaaccactt aaaagatgtt ggaaaagctt tgagagaaat cgttcaaaca agcgaaacgg
    55741 gatttcaagt aaccttgaca aaaatggcgc agtttttgat tgagacacat ctggtcgatt
    55801 tgtttctgat gcttcacgat cttgaaagca atctttcaaa ggaaacaaga gatcatcttt
    55861 tctttctatg gaagaaaaat tatcgtgaac cttttgaaga aatcttttca gcaaaccaat
    55921 ctgtgctaag aaatgggatt tcaaaagaaa tcgcagcaag gcattttttc ttagtgttag
    55981 caccttacat cactcggtcg aaaagacctg tggaagaacc gctaaatgtg gcgcaattga
    56041 tcgatttata tttgaatggt gtattaggag aagcgtaaag ctgttatata gggagaaaat
    56101 agttaggtga agaagcaaga tatgacgaag atcgttatat cttgcttctt tatataggta
    56161 gtttttcata aagacaaatt tgttattctc tcatgattat cagggtatat ttttatttat
    56221 tatgtcggtg ttccaggaag tgttttaatt taataacgaa gaaattaatt gtttgtagaa
    56281 tgaaggaaac tatttattgg gtagatgaat caccacgaat agtcaaaagg agatttcagg
    56341 atatgccaaa aatgaaaaaa atcattttag cagtaatgtt attttctacg gttatatctt
    56401 ttacagcccc ttttttgctt acttaagctg attttaagtt ttggccctta gtctggatct
    56461 acgaggtgag agtcaagaat gaaaaaaata attggagctt ttgtatttgc aatcattatc
    56521 attattatct gttttcaaat agatgttttt ggtcaaaaaa agatagttgg acaaacggtc
    56581 agcagtacga acagtacggt tacaaagaca aaggaatcat ttgatgatac agaacaagag
    56641 acattaatca aaatcggaaa aaatgaccgt acactatata cagatgactc gctaactacc
    56701 ccacttgcaa ctataaacgg cggagagctg gcggagtttc tttctgaaac aaaaaatgct
    56761 tatcagatca agacaaatga tggctatact ggatatttag ccctcgaaga tggaaccaaa
    56821 gtcacaaaga atatacaaac aaaaccggaa gagctatctg atgcagtgat tgtattagat
    56881 cctgggcatg gcggaaatga tactggggca ttaagcaatg atgaacaaac agaagaaaaa
    56941 gatataacat taagtacagc cataaaagta aaaaaggcgc tagaggatgc tggagcaacg
    57001 gtttatttga cccatactac agatgaatta gtacagcttg gagatatatg cgactacagt
    57061 gaagaaaaaa aggcagatgt ctttatcagt ttacacgcag actctacgga atatgcgaat
    57121 gaagcaactg gaatcacgac atattattac tatggacaag aggaaacatt agcacagaca
    57181 attgctgact ccttcactga tctgcctctg gattcaagag gaatctccac tgggaactat
    57241 caagttcttc gagaaaatct tcaaccttct attttaatcg agatgggtta tatgaataat
    57301 gatagtgatt taaaggaatt agtaacagac agttatcagc agcagattgc tgcaagtttg
    57361 acacaagcat tgaccactta ttttcagtaa taaataagcc cagccaaaca aaaatagctc
    57421 ctcatatttt tcgtttggcc gggcttatta tcgcagatgc aagcttttga acaccgttta
    57481 tttttttagt agcttcaaag ctttttctgt atttgcaaag tgaagtttgg catatttttc
    57541 aagcataggc atgccgcctt tctccaatag ttttgccgct acttggtcag atttcgttcc
    57601 agctcctgat ggaagggtga ttccagcttc agctgatgct ttgtgtaact cttccaaaaa
    57661 gctggcacga ctgatgatag aagcagcagc aacagctaaa tgatattgtt ctcctttagt
    57721 aacgaagtac agtttttctt gtaattgatt tttttctaaa cgcgcatatt ttttaaaatt
    57781 tgcttccggc gtaaactgat cgatcaaaat cgcttctggt ttttctggct cgattttttt
    57841 tagcagcaaa tggatcgctt gattgtgcaa agcgactttc atccgaacgg cattgtattt
    57901 tggttggatc tcattgtatt tttctggaga taagacaagc agtttatagg ggatggtttt
    57961 ttttaagatg tcagcaagct ggatgatttg gctatctttt aactcttttg aatctctaac
    58021 accaagttta cgtaattctg caagctgatc acgtttcaca taagcagcac atactgttag
    58081 cggaccgaaa tagctgccat ttccgacctc atcactacct aaaacggata attgactgat
    58141 attttttggc aaagaagagg ctgtttttgc tggcttggct tgtttatcct gtgcctcccc
    58201 ccatttatca gcttctattg ctgcattcgt accttgaaac atcacttttc cggatgtata
    58261 agcggtaatg gtcgtcccgt ctttttttgc agcaaagcta gtataaggaa tctgtttatt
    58321 taacaaataa gagcgatagt atgctttcat ttgactaagt tggtcgtttg ttgctttgat
    58381 aatgacgttg ctcataaaat tctcctcgtt tttatacata aaactatacc gcaactcacg
    58441 acttttcgtt ttctaagaga ttgcgagaca tagcattttt ttaaagttta tcatataata
    58501 gttaagtatg tgaaaaatat ttgtggagaa cggtgaaaga accaacttca tggtacacta
    58561 aataaaactt tcatcaaata ggaggaaatg attcgtatgg cgcacgaaaa aacacgctac
    58621 aaagcggtga ttgccaacca aacatatact attatcggac gggaaaccaa gcatcatatg
    58681 gatatcgtaa cgaagctgat caatgaacag ttagcagaat tgaaacaatt atcaccacaa
    58741 atggataatg aacaagcagc aatcttgatg gctgtcaatg cgctttcgga tcaattgaag
    58801 aaacaagaaa gaatcttgga gctggaagaa gaaacagcag aattaaagaa aaaaatgatc
    58861 aaatttacag agcttgaaaa tcgtgtgaaa cgcattgaag caatcgagaa cgaagctcgg
    58921 gaagtattga aagaaaatgg tcaagcagat cataccatta aaaatcatgt ggaagcacaa
    58981 cagattttaa acgagaaacg aaaaggacaa attaaacaaa aatcttctaa ttaagatcct
    59041 tttatcaaaa taagaaaaat ttaaaaaaag ttagaagaga aaggaacgta gcatgctgag
    59101 tttgctgatt ttatttttat tgctaattgc gtttttttct ggagcacgtc gcgggtttgc
    59161 tttgcaaatc atattcgcga ttggatatgt attgtcattt attgctgccc agcattttta
    59221 caaaccatta gcaagtcatt tggaattata cattccatac ccagctgtca cgccaacatc
    59281 aaagttagca ttttttgatc aggtatttgc ctttcaccta gatgaagctt tttatgcagg
    59341 aactgctttt ctgattattt tgctaattgg ctggctgctt acccgatttg tgggggtttt
    59401 tgtccatgga ttgacgtatg tgccgatctt gagacaggta gactggattg caggaggcat
    59461 cctgtcacta atcatggctt acgttactat atttttgatt ttgcagttac ttgcctttgt
    59521 tccattagat gtggtccaaa atcaattcgg cgagcatagt ttcgctcgct ttatcgttga
    59581 gagaacgcca tttcttacca acaagatgta tgagctttgg gtaacgaata ttttgaatta
    59641 aggaaaatag tgctggaaaa tatttcgttt tttgtacaga gtagattatt taagaaggct
    59701 gcgtagcgta tgtccggcac agctcttttt tcatagtgaa agataaggtg ataaaatgaa
    59761 taaccgaatc cttgaaacat tggaatttga aaaagtcaaa cagatggtca gacaatttgt
    59821 agtgactgca caaggaaaag aagaactggc agaattggta ccagtgagcg aggaacaaac
    59881 gatcacaaac tggcttcaag aaactgagga tggattgaaa gtgcaacgtc tgcgaggcgg
    59941 gatccctata cctaaacttg aaaatatccg tccccatatg aaacggattg agatcggagc
    60001 agacttgaat ggagtggagc ttgcacaagt ttccagagta ttgtctacga caagcgaatt
    60061 gaatcgtttc attgatgatc tttatgacag tgaaatcgaa tttgcacgtt tgtatatgtg
    60121 ggcagatcag ttagtcacga tccctgtttt gagccgccgt ttaaaggaag caatcgatga
    60181 agacggacgc gtgactgatg acgcttctcc tgagttaaag agcataagac agaacattcg
    60241 gcgaagtgaa caagctgttc gtgaacagtt agatgggatc gtccgtggga aaaatgcaaa
    60301 gtatttaagt gatgcgatca tcaccatgcg aaatgaccgc tacgttatcc cagtcaaaca
    60361 agaataccgc ggtgtatttg gcggtgtagt ccacgatcaa agtgcttcag gacagacttt
    60421 atttattgaa ccaaaacaag tggtggattt gaataatcgt ttgcgtcaat accaaatcgc
    60481 tgaacgaaat gagattcaac gtattttaag tgaactttct gctgaacttg ttccccatcg
    60541 tcaagaaatc atccacaatg cttatgtgat tggtaaaatg gatctgatga atgcaaaagc
    60601 acgatttggt aaagaagtaa aagctatcgt gccgggaatc agtgaagaca atcatgtcgt
    60661 cttgaaacaa gcaagacatc cactgatcga tcaggaaaaa gtagtttcta atgacatcac
    60721 aatcggaaaa gactatcaag ccatcgtcat tacaggacct aacacaggtg ggaaaacgat
    60781 cacgttgaag actttaggtc tgttacaact gatggggcaa gcaggattac cgattcctgc
    60841 aggtgaagaa agtcaaatcg gtatttttga ggaagtattt gcggatatag gagacgaaca
    60901 gtcgattgag caaagtctat cgaccttttc ttctcatatg acgaacactg tagatatttt
    60961 atcaaaagtc aatgaaaaaa gtctggtatt atttgacgag ctcggtgcag gaacagatcc
    61021 gcaagaaggt gctgctctag caatcgcaat cttagatgat cttggtaaaa agtctgctta
    61081 tgtgatggca acaacgcatt atcctgaatt gaaagtttat ggatataatc gggcaaatac
    61141 gattaatgcc agcatggagt ttgatgtgga tacattaagt ccaacgtatc gtttgctgat
    61201 tggcgttcct ggacgaagca atgcgtttga aatctctagc cgattaggtc ttgatacaga
    61261 agttattgat gaagcgaagc agttgatgaa tgatgagagc caagatttaa acgaaatgat
    61321 cacagattta gagaatcgcc ggaaaatggc agagaccgaa tatctggaaa tgcgtcattt
    61381 tgtttctgag gcacaagaac ttcacgatga tttgaaagaa gcttacagct atttctttga
    61441 agaacgtgaa aaagaaatgg aaaaagcaaa gaaaaaagca aatgaagtcg tgtcagaggc
    61501 ggaagaaaaa gcagaaaaaa tcattgctga tattcgtaaa atgcaacagc agattgggca
    61561 aggaaatgtg aaagagcatc agttgatcga tgcaaagacc caattagcaa atctacatca
    61621 agaagaaact ttgaagaaaa ataaagtatt gaagaaggcg aaagaacaaa aaacgttgaa
    61681 accgggagac gaagtgttgg ttacgactta cggccaaaga gggacgcttt tacgtaaaaa
    61741 cgggaatcag tggcaagtag aaatcggtat attaaaaatg aatgtgtccg aagacgagct
    61801 gacgcctgtt gctcctcaaa aagagccgac acaacgagtt atccatgctg tacgatctga
    61861 atctagtagt cacgtgccga atcaattgga ccttcgagga aaacgatacg aagaagcgct
    61921 aagtgaggta gatcaatatt tggattctgc cattctagct ggttatcctc aagtgactat
    61981 tgtccacgga aaaggaacag gcgcacttcg caagggaatt actgattatc ttaaaaacca
    62041 tcggagcgtc aaaagctttg agtttgcacc ggcaaaccaa ggcggaaatg gtgcgacaat
    62101 tgttaaattt aagtaaagct tactaaaggt aagcagatgg ttcgctatcc aagtatagaa
    62161 atgctatact agtcatagat tttaaaaatg gaggtctttg atatgtcaca agtaattaca
    62221 gataagacat ttaatgaaga aacagataaa ggacttgtat tgattgattt ttgggcaact
    62281 tggtgtggtc catgtcgtat gcaagcaccg attttggatc agttggaaca agaatatgat
    62341 gaagaagaat tcagaattgc taaaatggat gtggatgaaa atccagaaac tcctcaacaa
    62401 ttcggtatca tgagcattcc aacattaatg ttgaaaaaag atggtcaagt agtagaaaaa
    62461 gctgttggtg ttcattcaaa agaacaacta cgtcaaatga tcgatcaata tttataaaaa
    62521 cttacagcaa aaataagctg agggtgggac tgaatccagt tccgtcctcg gtttttttgc
    62581 ggttgagtta aggttattca aattaatatt ttttgagtat aattacgttg tcaggctgga
    62641 ttgttttttt gacagacatg ctataataac tttaattgaa tatgaagggg agtaccagat
    62701 gaacgaacga atcaaaaaca aattagcttt acttcctgat cagcccggct gttacttgat
    62761 gaaagataaa aatggaacga tcatttatgt cggcaaagcc aaaatattaa aaaatcgtgt
    62821 ccgctcatat tttactggta gccataatac gaaaacggaa cggcttgtta gtgaaatcga
    62881 agactttgaa tacatcgtta cagaatcgaa tatcgaagca ttgctcttag agatcaatct
    62941 gataaagaaa aatgatccta aatacaacat tatgttaaag gatgataaaa cctatccttt
    63001 ccttaagata acgaatgaaa aatatccccg tttggtgatt actcgtaagg tactaaaaga
    63061 caaagcactg tattttggac catatcccga tgtcggtgcg gcgaatgaga caaagaagat
    63121 cctcgatcga ttatttcctc tgagaaaatg caaacctagt cagacgaagg agccttgtct
    63181 ttactatcat ttgggacaat gtctgtgtcc ttattatttc gacgtagatc cgaaagtcta
    63241 tacgaaaatc gttgatgaag tgaaaaactt tttaaacgga ggacacgaaa aaatcgagtc
    63301 agagatccat cagaaaatgg aaaaagctgc tgaaaacatg gagtttgaaa aagctgcaga
    63361 ataccgagac cagatccgtg ccattgagac aatcatgact cgccaaaaaa tgacaaatac
    63421 tgatttactg gatcgagatg tatttggtta tgcgattgat aaaggatgga tgtgtgtcca
    63481 agtgtttttc gtaagacaag gaaagctaat tgaacgagat gtttcaatgt ttcctttcta
    63541 taacgaagca gaagaagatt tcttgactta cctcggtcag ttttatcagg aaaatgagca
    63601 tttcattcct aaagaagtct tgattcctga tacgatcgac aagcccagtg tagaagcttt
    63661 gttagctacg aaagtgctgc aaccaaaacg aggagaaaag aaaaaattag ttgaattggc
    63721 gagtaagaat gcctcagttg ctttgaatga acggtttgat ctgattgcca gaaaacagga
    63781 acggacgatc ggagcagttg aacgtttagg aaacgcgatg aatatcccga ccccaatacg
    63841 tatcgagtct tttgataact ctaatatcat ggggacgaat cctgtggctg cgatggtcgt
    63901 attcattgat ggaaaaccgg caagaaaaga atatcggaaa tataaaataa aaacagtcaa
    63961 cggaccggat gattatgcat caatgagaga agtcatctat cgcagatatt cgcgagtgat
    64021 tcgcgaaggg ttgcctttac ctgatttgat cttgatcgat ggaggaaaag gacaagtaga
    64081 tgtggcaaaa gatgtcttag aaaatcaatt aggaatcgat attcctattg ctggcatggc
    64141 aaaaaacgat aaacataaaa caaatgagtt gctattcggt acagatttgg ctgtagtacc
    64201 gcttgagcga aattcaccag agtttttctt actccagcga atccaagatg aagtccatcg
    64261 attcgcaatc actttccatc ggcagctacg cagtaaaaac agttttgctt cccgattaga
    64321 tgaaattgaa gggttaggac caaaacgaaa aaaaatgctg cttaaagagt tcaaatcgtt
    64381 gaaaaatatc acagcagcca cgacagaaga attacaagaa atcggactgc cgaaaaatgt
    64441 cgcacaaaac gtatttgata aattacatca ggaatgagga aagggcactt tacaaagaaa
    64501 gtaaagtgtc ctatcatttt atgtacaaca aaaagagcgt ttacgttttg ttggtaaata
    64561 ataaatcgct tacgtctggt gtctaaggat atatgtgatt tcttgaagaa ggagtgaaga
    64621 aatgttagaa gtcaaggatc ttgttaaaac ttttgggaac tacacagctg tcgatcatgt
    64681 ctctttccaa atccccgatg gaaaaatcat ggggctaatt ggccaaaacg gggctgggaa
    64741 gacaacgact tttcgtttga tcttggattt tttgacacaa gaccaaggag aagtgttatg
    64801 gaatggccat catcttgggg agaaagatta tgatgtcatc ggttatcttc cggaggaacg
    64861 gggactttat ccgaaagtaa cgattcaaga ccaactgctt tattttgcag aacttagagg
    64921 gaaatcaaga aaagagattg aaccaaaaat cgacttttgg atggaaaaat ttcaggtaaa
    64981 agggaaaaag acggataaag taaaatcttt gtctaaagga aatcagcaaa aagtccagct
    65041 gatcgccacg ttaatccatg aacctaaatt gatcattttg gatgagccat tcagcgggtt
    65101 agatccggta aatgctgaat tgctaaaaga tggaatattg gaattgaaaa aacatggttc
    65161 atgtgtcatt ttttctagcc acaatatgga taatgtagaa aaaatctgcg atcatttgat
    65221 catgttgcga aacggaaaaa tggttttgaa tggaaaagta catgagattc gtgaatcatt
    65281 tggccgtacg aagttattct tggaatctgg tttaagccaa caggaagtag aagaaatcga
    65341 aggcgtgaaa aaagtgatcc ttcatgaaga caatacgtta gagattacct tagaagatcc
    65401 tgaagctggg aaagaaatct ttactcgtgc gactcagttc ggctacattc ctatgtttaa
    65461 ccagcaaccg ccaactttgg aagagatttt caaattgaaa gcaggtgaaa tcgatgcgta
    65521 agttttggat tattaccaaa gatgtctatt taaaaaatgt taagtcgatt tctttcttga
    65581 tcatgatatt agtccctttt atcatgctgg gtatcattta tgtagcagga aactttgctc
    65641 aacaaaatag tgatgtcaat aaaatcggcg tattggctga taatgagcaa atcagtcagc
    65701 aaatgagcca agtcaaaaca gatgattttg agttcaaagc agttgattct gaagaaaaag
    65761 cacaaaaaga gctttcggaa gaaaaaatcg atgcgtattt agtagtctca actgagaatg
    65821 ataagataaa tgggatgctt tatagcgaaa attcattagg acaaagtaca caactactga
    65881 tacaacaaca actgactggc ttgcaatcga tgcttcgagc gagtcaatta ggcatttcac
    65941 cagaagaagt agctagcttg agccaacaag caagtttgac tcgacaaaaa gtcaattttg
    66001 attcaaaagg aaaaatgaca gtcggagaag ataactcgac agtccaatac gtcgtaagtt
    66061 atgtagcaac gattgtcttg ttcattatta ttttgacgta tgcgcagatc attgcacaag
    66121 agatcgcttc tgaaaaaggc acgcggatca tggaagtgat cctgtccagt acgactgcac
    66181 aaaagcattt ttacggaaaa ttaacaggtg ttttacttgt tgcattaacg caaatggcat
    66241 tatacggtat tatttttggt ataggataca gtcaattcaa agatatggaa atggtcaaaa
    66301 atatattaga cggtatctca ttggataact tgattggacc attcttgtgg tattctcttc
    66361 tattcatgat ctttggcatt ttgatttttt ctgttttagc agctttatgt ggctctttgg
    66421 tcaacaaagc agaagataca gcaaaagcaa ttttgccagt gacttatcta tctctaggcg
    66481 gatacatgct tggattgata ctaggagctt cagatccaaa caatatcgtt attcggatca
    66541 cttcgtatat tccattctta tcttcatata ttatgccggt tcgcttagca aatgagacag
    66601 tcggtatggg tggagcattg atttccttgt tggtacttgt agccgtaaca ttcttattga
    66661 tgatcttgtc tgcaaacatg tacaaatcga atgtactcgt ttatagcgaa ggcggattat
    66721 ggagttcatt gaaacaatcg atttcaatta tgaggaatga acgaaaaaaa gcataaaaca
    66781 atcctaaaat acagaaggaa gctggacatc tattgttccc agcttctttt tgtatagacc
    66841 tattttattt attttactat attggatata tattcattga aaatagtgta taacaacttt
    66901 ataatattga gtataccaat ttttggaggc gttttaatgg accgttattt agatttactt
    66961 tcagaaaaat tcccctcaac ggaggatgtc atcacggaaa tcatcaatct cgaagcaatt
    67021 ttgcagcttc caaaaggaac agagttattt ttgagtgata tacatggcga atttcctgct
    67081 tttgatcata ttctgcgtat cggttcagga aatcttaaag aaaagatcaa agaccttttt
    67141 tctgaacaaa tgacggaaac ggatatcagc caattcacta tttttacggc ttatccagaa
    67201 tatgcattaa cgactgattg gtacaaagaa caagataaat cgcagctgat ccatcatttg
    67261 atcgatcttt tacggtttac gacagtcaaa tatacccggt caaaagttcg aaaaggattg
    67321 ccgaaagaat atagctatat cattgaggaa ctcttgtata tcgatgaccg tatcaatgga
    67381 aaaaaagact atgtaaaaaa aatcattgaa caacttgttt tgatgaagga agaagaaaaa
    67441 tttttaacga aacttgcaca gacgatccaa aaatctgtca tcgatcattt gcatatcgtt
    67501 ggagatattt ttgaccgagg aactcaagca gccaaagtga tggatcgaat catggatttt
    67561 tcttctgtag atatccaatg gggaaatcat gatattttgt ggattggtgc gtattgcggc
    67621 tctgaggcat gtttactgac acttttacgg attgcagcac gctataatta tttatttgaa
    67681 ttagagaaag aatatgggtt gaatttacgt ccattgtttt cttttgctca tcaaacttat
    67741 cagaagaatc cagtatttgc gcctaaaaac agtaaaaatc tatccgaaag agagcaagaa
    67801 gaattagaaa aaatccatca ggcactttct atccttcaat tcaaatcaga acatcagtta
    67861 ttggatcgtc gacctgaatt taaaatggac gatcgtaaat tgctggaaaa aatcgactat
    67921 gaagcatcaa cgattgattt agaaggtcag ctctatgagt tgaaaggaac ttgttttcaa
    67981 acgatccagc cagatgatcc aaaaaaattc ttggaagagg aacaaaaagt gattgatagt
    68041 ttgatgtatt cattccagca ctctttgaga atgcaaaaac atatgacgtt tttgatcgaa
    68101 aaagggggaa tgtatctcac gaacaatcag catgtgctgt ttcatggctg tatacctgta
    68161 gacgagaagg gacagctctt agcatttgaa ttagaccaat cttatcgcgg aaaagaactg
    68221 ctgggctttt ttgaaaaaca gataactgaa agcgcaaaag atctgactgc aaaagaagat
    68281 ttagcaaccg atttgatttg gtatgcgtgg agtgggccat tttcgccttt attcggcaag
    68341 agtaaaatgg cgacttttga acgttatttt ctcacagagc ctcatacgca cgtcgagaaa
    68401 agcaatcctt attatcactt gcgagatgaa gagtggttca gtgaaaaaat tttagcagaa
    68461 ttcgacacaa aagaagaagg gtcagcaatc attaatgggc acacgccagt aaaagtaaaa
    68521 aaaggggagt caccgatcaa agcaaatgga aaagtatttg tcattgacgg aggtttatcc
    68581 aaagcttatc aaaaaacgac aggaattgcc ggttattcac tattatgcaa ttcttatggt
    68641 ttccaaatcg tgacacatta tccgtttttg cctattgaac aacaatttgc aaaaaaatcc
    68701 gaccaaacaa atgtgaaaaa agtaatcgaa cagcaactac cacgcaaact caatcgtgat
    68761 acaacaaaag gtatggaact gcagcagcag attacccagc tcaaaaggct gttggactat
    68821 cgaaaggacg attgagaaga attccagtga acattgttcc atagactgga gactgagaca
    68881 aaagtcgtgt cgcagtctct ttttccggat aaacggtgtt cttctgccaa ctcctcggtc
    68941 acaagtcaca ctattcaaca aacatgaaaa gctgtttttt gaaattgctc cttgtgactc
    69001 agagttgaac ggcaggctca cgacctcttg gtataaacgg tgttcaaaag ccagtttctc
    69061 ggtattaagc caaatttatg caaaaatgtg aaaagccatt ttcacaaaat ttttcttaat
    69121 actcgaaact aaacagcttt ttcacaaccc cctcagaaag tctattaaaa ttcattcaca
    69181 aagaaatcga ataagcgctg ttcagatgga tgtacacggt gggtaagttc cggatgccat
    69241 tgaacaccga ggattttatg catatcatct ttgctttgaa ccgcttcaat gagtccatcg
    69301 ttagaaaaag cgatggcttt taataaaggt gaaagatctt tgactgcctg atgatggtaa
    69361 gaattcacaa aatatggatc ggggagaagg ttgcttaaca aactgtctga aacaatcttg
    69421 acttcgtgag tcgtaaattg cggggcagtg ggctgttgtt catgttttac tgaccacttt
    69481 ggatataatg aaagatcttg ataaagtgta ccttccaaaa cgacattcaa tagttggagt
    69541 ccccggcaga ctgcaaaaat tggttttctt tgtttcaatg cttccaagat cagtgcctgt
    69601 tcaaattggt ctcgttgaat atttgtttcc gttagctttg gatgaggatc ttccatgtaa
    69661 agttgtggac tgacatcttg accacctgca agaataagtt tgtcgatttg tccaatcagt
    69721 tgaggagctg aatctggaga catgactggc agaataagag gcaatccttg agcatctaaa
    69781 actgcatcca cgaatccttg cggtgtatag ctcacttgat ttccttggaa agtatctgtt
    69841 gctcgaatca gttgatttcc ggcaatgccg atgattggtt tcatttgtat tccccctaaa
    69901 gtagacttat tgtaacaagg atttaaaaaa aattaaacta tgtaagactt gcccctatac
    69961 ttatctgttc ttgctgtgtt actatctgta aagagaaatt tcgtgtgaaa ttcatgacga
    70021 tagttgaaaa tattgcttaa tttgttataa taaaaagtaa gcagaaataa aaaggttggg
    70081 cgtaagcttc aaggatctag ttcttcaagg ggtgagaagg acattttatt gaaggggcct
    70141 gcctatacta agttatcttt agaggtacat actttcaatg aaaaaagaaa gcatgtacct
    70201 cttttttaaa tcgaaaggaa gtgaagcaag tgttagaagc tttggaacaa atccgaaaag
    70261 cagaagaaga aaatgaaaag cgtgctcaaa cactgcggca gcagctgaag atctatgcaa
    70321 cagaaaaaga gcaggaattg gaaacgatcc aaacaaacta tcgacaacaa ctaaaacagt
    70381 tggtggaaga aaaagaacaa tttgaaatac aagaattaga aaaagaaaaa atgaaattga
    70441 aagcagaagc agacaaggtg caagcaactt tgaaagatca atatcaaaag catcagagtc
    70501 aagcgatcgg tgcgatcatt gaaagggtga aagaaactta tggccgtcac taagatggaa
    70561 aaagtgaccc tcatttcaga taaaagaaat caggagagga ttttacaagc agtacaagga
    70621 atccaaaacg ttgaaatccg ggatctgtat caaaatagaa caaacaacca gtgggtggag
    70681 aagtattttc cagataccac gattattgat aaagaagcaa aattaagcgc tttaggtaat
    70741 cggttgaaag acatccaaga agctatccaa ttcatacaac accacggcga tagccgtcaa
    70801 aagaaactcc atttgaaacg tcaagaactt tccttacaag atttggaagc caattattcc
    70861 gaagaaaatt tcataaataa attgaaagaa gtccttgatt taaaagaaaa gtgggaacaa
    70921 ctaactgaag aacgtgatcg tttagaagaa gaggaagaat ggcttcttca ttggcaacag
    70981 ctggatattg ctccaagtat gtatgcaagt aagacgacca tttttgagat ggggactgtg
    71041 agtgcagcaa attttgaaag tttcaaggaa gaactgagta agcttgatga cgtttatatg
    71101 gaagaaatag attatacgcc aaaacaagtt tatctttcgt atgttgcttt aaaaaaatca
    71161 gttgctgtta tagaagaaat tgctgggaaa tacgggttca ataaagaaac gtatccttat
    71221 gaacaaaatc ctaaagaaaa actgcaagag accaagcagc aattatccat tgttcacgag
    71281 cagcaaaaga agataacgac agcgttaggt cagtgcagtg gctatatcca agaatttgaa
    71341 tgggtagaag aagtcacact tgccgttgca gaacgagaaa aaataaaaga acggtttatc
    71401 catgcgactt atctgatcgt tttgcaaggt tgggtagatg cagaagaaaa acagaatttg
    71461 ctgcatgtgt taaacgaaac cgtatcagaa gaagatatat acgtcagttt cgaaacacca
    71521 aactcagaag agattcagca ggaagtccct actaaattga aaaaccatcc gcttgtcgaa
    71581 ccttttgaat tgctgactga aatgtacagt ctgccaaaat atgaagaagt agatccaaca
    71641 ccttggatga caccatttta tcttgtcttc ttcgggatga tggtcgcaga tgttggttat
    71701 ggtttgctga tgctcattgg gacaatacta gctcaaaaac tacttgttct accacgcggg
    71761 atgaaacgtt tcgtaaaatt ctttgagatt ctctcgatac catcgatcat ctggggattg
    71821 atctacagtt catttttcgg acagtcatta ccaaaagaac tgtttggcat ccgcttgcct
    71881 ttcccaatcc tatctacgac ggatgacgtc aatacgattt tgattttatc cgtgattttc
    71941 ggtctgatac agattttggt tggattattt gtggcagcaa aggaaaatat caggagaaaa
    72001 gattacttga gtgctgtcag tgatggattt gcctggcaag ggatcctaat tgggatcgtt
    72061 attgcgttgg ttggtgccat gttgataaaa aatacagcat ttgtttacct tggcgctggg
    72121 ctatcgatca ttgctgcctt atgtatcttg atcgttccga ttatccaaac gccgtctaaa
    72181 gtcaaaggtg ctgccaaagg tgcgtataat ctttacggac tgaccggcta tatcggtgat
    72241 ttagtcagtt atacacgttt gatggcattg ggtatttcag gcggaagtat tggagcggca
    72301 ttcaatatgc tagttgcttt catgccgcca gctgctcgat tcagtgtagg gatccttttg
    72361 atcatcgctt tacacgcact gaatatgttt ttgacactgc taagtgccta tgtccatggc
    72421 gcacgattgc agtatgtcga attttttggg aagttttata caggaggcgg acgtgccttt
    72481 gatccgctga aaacggcgga aaaatacgtc aacatcaatc acaagaaaaa aaacaataaa
    72541 taattggagg atttttatat aatgatggat tacttaatta gtcaaaatgg tggaatggta
    72601 tttgcggtat tagcgatggc aacagcgacg attttttcag ggatcggttc agctaaaggt
    72661 gttggaatga caggtgaggc agcagcagca ttgacaacaa gtcaacccga aaaattcggg
    72721 caggctctga ttctgcaatt gcttccaggt acgcaaggtt tgtatggatt cgttattgcc
    72781 tttttgattt ttatcaactt aggaaatgac atgtcagttg tacaaggact gaactttcta
    72841 ggtgcttctc tgccgattgc ttttacaggc ttgttttcag gtattgccca aggaaaagtc
    72901 gcagcggcag gtattcaaat tttagcgaaa aaacctgaac atgctacaaa aggaatcatt
    72961 tttgctgcga tggttgaaac atacgcgatt ttaggtttcg ttatttcctt cctattagtg
    73021 ttgaatgcct aagcataaag gaggaaaagc agatgaacgc cattgaaaaa atcatctctc
    73081 agatgaacga agcagcagag caggaaagag cggcgttaga acaagaagag cgaatgaaga
    73141 tcgatcaaaa ctttgaacaa aaacgtacgc aagttgaaac agaacatcaa aaacaaaaag
    73201 aaaaacaaat cgaattactc gaaaaaaaat accgtcagct aaggaatcgc cagcaagtag
    73261 aagtacgaca agaaaatttg aatgcgaagc aggaattttt aagacgattg tttgcagatg
    73321 cggtaactga aatggaaaat tgggatgaat ctgaacaaat ccagtttatc aaaaatgcat
    73381 tgtattcatt acctttgaca ggaaaagtag cattcattgc tggagaaaaa tcagcagcct
    73441 atctttctca gacgttgttg gatgaatgga acaatgaact tccctttatg atggttttaa
    73501 gtgatgaaac tgttgctgat caagcgggtt ttctgataaa cgatcaagga gttcagtata
    73561 attttctttt cagcagcctt gtacaagata tccaaggaac gatgagtttt gagattgcca
    73621 atcaattatt cgaataagga gggatcagtg tatggaatac cacgaactaa atcccttgat
    73681 tcgcggaaga gagcttgaac ttttgtccaa tgagacattt gaacggatga ttcaaacaaa
    73741 ttctgtcgaa gcacttggtg aaatattgaa atccacgatt tacagtccat atatttatga
    73801 cggatatgaa tatgacttcg aacagaatct tttaaaggag cagagccgtc tatttcgctg
    73861 gttaaaggaa tcagcaccgg agcctgaaat cgtttggatc tatacgatgc gttatacttt
    73921 ccataatctg aaggttttga caaaagctga gatgacaaat caaaatctgg accatttgta
    73981 tatcgacgat ggattttatt cattagaaac cttgaaggat gccattcata cgcaagtttc
    74041 aaatgaactt cctgaaagca ttatggacag tatacgagaa gtacgtgatt attttgaaga
    74101 gtctaccatt cttcagggaa ttgacgtgat ttatgatcga cagtttttga cagagcagcg
    74161 acggcttgcc gataagctag gatatcaaga attgctgaca gaagtcattg cttttattga
    74221 cttgaccaat atcacaacga tggctcgagg aatattgcag aaaagaacat atgggttcat
    74281 gacgacggta ctttccagct cgggaagtat cgaaaaagaa gtatttttga actttgtaga
    74341 taaagatatg gaagattaca cgaattttct attagagaca gattatgctg attttctgcg
    74401 ccctgtcatc cgtgagggaa atattgatct cgtaaagctt gaacagttga aagatgatta
    74461 tctaagttca ttgtatcaag aagcacaaac ccaggctttc ggaccactgc cactactagc
    74521 ctttttgaac gcaaaagagg tagaaagcaa aaaccttcgt ttactggtta tcggcaaaag
    74581 aagccatttc gaatcagaaa caatcagaaa gcgggtgaga caagtctatg acgcataaga
    74641 tcggtgtagt tggcgacaaa gattctgttt tgccattcaa attgtttggc tttgatgttc
    74701 gttatggtac aaccaagcaa accgttcgtc aggcaattga agaaatggca aagaatgagt
    74761 atggcgtgat ttatgtcaca gagcaatgtg cagcattgag cccagaaacg atcgaacgtt
    74821 acaaggaaca aatgatacct gctatcgtat tgattcccaa tcatcaagga tcattaggga
    74881 tagggctgga agaaattcaa aaaaacgtag aaaaagcagt aggtcaaaat atcttatagt
    74941 atgaaaagga gatagaaatt ttgcaaattg gaaaaatcat aaaagtctcc ggacctcttg
    75001 taatggctga gaacatgtct gatgccagta tccaagacat gtgtctagtg ggagatctag
    75061 gagttatcgg agaaattatc gagatgcgtg gcgatgtggc gtctattcaa gtatatgaag
    75121 agacttctgg aattggtcca ggcgaaccgg ttcgctctac tggtgaagct ttatctgttg
    75181 aattaggacc agggatcatt tcacaaatgt ttgacggaat ccaacggcca ttagatacct
    75241 ttatggaaat cacacaaagt aatttcttag ggcgcggagt tcaattgccc gcattggacc
    75301 atgagaaaaa atggtggttc gaaccaacag tagaagccgg agaaacggtg agtgctggag
    75361 atgttatcgg gatcgtagaa gaaacaaaag ttataaaaca taaaatcatg gtgccaaatg
    75421 ggataaaagg aacgatcaaa acaatcgaaa aaggttcatt cactattgat gaaacagtat
    75481 gtgtcattga aaccgaaaat ggtgacaaaa atttgacgat gcttcaaaaa tggccagtaa
    75541 gacgtagtcg gccaatcaaa gaaaaattaa acccggatgc acccatgatc actggacagc
    75601 gagtgattga tacattcttc ccagtgacaa aaggaggagc agcagctgta cctggtcctt
    75661 ttggtgcagg gaaaacagtc gttcagcatc aaattgcaaa atgggccgat gtggacatgg
    75721 ttgtctatgt gggatgtggc gagcgtggaa atgagatgac ggatgtttta aatgaattcc
    75781 ctgaattgat tgaccctaat acaggagaat cgttgatgga acgtacggta ttgattgcta
    75841 atacatcaaa catgccagta gcagctcgag aagcttctat ctatacggga atcacaattg
    75901 cggaatattt ccgtgacatg ggttatgacg ttgctatcat ggcagactcc acttcacgat
    75961 gggcagaagc acttcgtgag atgagcggac gtttggaaga aatgcctggt gatgaaggtt
    76021 atccagctta tcttggttca cggcttgcgg aatactatga acgatctgga agagtcattg
    76081 cattaggatc agaaggtcgc gaaggaagta taaccgcaat cagtgctgta tccccgtctg
    76141 gaggggatat ttcggaacca gtcacacaaa atacattgcg ggtcgtaaaa gtattctggg
    76201 gtcttgattc cagtttagcc caaaaaagac attttccttc gatcgattgg atacaaagct
    76261 attctcttta ttcaacagaa gtagggaagt atatggatca tatccttcaa gctgactggg
    76321 catccatggt caccgagggc atgcgtattt tgcaggaaga acagcagctg aatgaaatcg
    76381 tgcgtttggt agggattgat tccctttcag ataatgaccg tctgacatta gaagtggcaa
    76441 aatccattcg tgaagattat ttgcagcaaa atgcttttga tgatgtcgat acattcactt
    76501 caagagagaa acaattcaaa atgttgaaga tgatcttgac ctttggtgaa gaaggacgcc
    76561 gtgcgttgtc gttaggtgct tatttaagtg agatcatgga cggtaccgta tcgattcgtg
    76621 aaaggatcgg acgaagcaaa tatatcccgg aaacagaatt agaaaaacta gatcaaatta
    76681 ttggtgaaat caagcaaacg atgcaaacga tcgtttcaga aggaggcatg agcaatgatt
    76741 aaagaatatc gtacgatcgg tgaagtcgtc ggtccattga tggcggttga aaaagttgct
    76801 ggtgtcaaat atgaagaatt aatcgaagtc cgtatgcaaa atggcgagat tcgtcgtgga
    76861 caagtattgg aagtccaaga agataaagca atggtccaaa tattcgaagg aacaagtggt
    76921 atcaatttac gtgactcttc tgtacgattt ttaggccatc ctttagaact aggtgtatcg
    76981 gaagacatga tcggtcgagt attcgatggt ttgggacgac cgaaagataa cggaccagag
    77041 atcctgcctg aaaagcattt ggatattaac ggagaagtaa tcaatccagt agctcgggat
    77101 tatccagatg agtttatcca aacaggtatc tctgcaatcg atcatttgaa tacattagtt
    77161 cgtgggcaaa aattaccagt attttctggc tctggtcttc ctcataaaga attagctgct
    77221 cagatcgcgc gacaagcaac ggtactcgat tcatcagatg atttcgccgt agtctttgct
    77281 gctattggaa tcacttttga agaagctgaa tttttcatgg aagattttcg tcaaacgggc
    77341 gcaatcgacc gttctgtcat gtttatgaat ttagcaaacg accctgcaat cgaacgtatc
    77401 gctactcctc gtatggcttt gactgctgca gaatatcttg cttatgaaaa gggaatgcat
    77461 gttttggtta tcatgacaga catgaccaac tatgcagagg cattgcgaga gatttctgca
    77521 gcacggcgag aagttccagg aagaagagga tatcctgggt atctttacac gaacttagct
    77581 actttattcg aacgagcagg aagaatccgc ggactaaaag gatcggttac tcaaattccg
    77641 attctaacaa tgccagaaga cgataaaact catccaatcc ctgacttgac tggttatatt
    77701 acagaaggac agatcatctt gactagagag ctttacaaga gtgggattca gccaccaatt
    77761 gatgtactcc cgtctctttc gcggttaaaa gataagggaa ctggacccgg aaagacaaga
    77821 gaagaccatg cagctacgat gaatcagctt tttgcagcct atgcacaagg aaaacaggca
    77881 aaagaattag ccgtagtttt aggtgaatct gctttatctg atgtagacaa gatctatgcg
    77941 aagtttgctg agcggtttga aaaagaatat gtcaatcaag gattctacac gaaccgttcg
    78001 attactgaaa cacttgatct agggtgggaa ctgctatcga tgttgccaag aaccgaatta
    78061 aaacgaatca aagacgacat gctggacaaa tatctgccag aagggaagtg agttctgatg
    78121 gcacgattga atgtgaatcc gacccgcatg gaattgactc gattgaaaaa acagttgaca
    78181 actgccacaa gagggcataa attattaaaa gataagcaag atgaactgat gcgtcaattc
    78241 atcctgttga ttcgaaagaa caaccagctg cgtcaagaaa tggaagagtc tatgacagaa
    78301 gcaatgtctg attttgtatt ggcaaatgct tcgatcacgg aacctttcat cgaagaatta
    78361 tttgttttgc cggcggaaaa cgttgatttg tctatcgtag acaaaaatat catgagtgta
    78421 aaagtacctg tgatgaattt tgaatatgat gaacagctga cagacacacc tttggaatac
    78481 gggtatttga attccagtgc cgaactggat cggtcaatcg atcggtttac taccctgctt
    78541 ccaaaacttt tggaactgac agaaatcgaa aaaacttgtc aactgatggc gagtgaaatc
    78601 gaaaagacac gtcggcgagt caatgcatta gaatatatga cgatccctca attagaagaa
    78661 acgatctatt atattcgtat gaagctggaa gaaaacgagc gcgcagaagt aacaaggttg
    78721 atcaaagtaa aaaatatggg taccactgac taagtggtat ctttttttaa aagaggaaaa
    78781 cgatgattaa acaaagcaaa caaataaaga aacgtttgcc ggctgttcag cttctcgcat
    78841 taggattttt tctcctgatt ttagttggcg gcggcctact taccctacca ttttttagta
    78901 atagtgggca tgggacaaat tttatcgatg cgcttttcac tgcaacttct gctgtctgtg
    78961 taacgggatt gacaacattg aatacagcag agcattggaa cagtgctggt caatttttga
    79021 tcatgctttt gattgagatc ggcggtcttg gttttatgat ggttccgatt ctatgctttg
    79081 cattgataaa gaagaaagtc agtctcagca cacgtattat attaaaagaa gcgctgaatc
    79141 tagaagaagt atcaggtgtg atgaagctca tgctttacat cctaaaattg gcctttgtga
    79201 tccaattgat tggtacggtt gctttatctt ttgtatttgt gcctgaattt ggctggttga
    79261 aaggtatctg gtacagtttg ttccatgcaa tctctagttt ttgtaatgca gggtttgatt
    79321 tgttaggaga cagtttagcc aatcaccagc aaaatgttta tttgatcatg gtggtatctg
    79381 ctttgatcat ttctggtggg ttaggcttca tcgtatggcg tgatttactg gaatatcatc
    79441 agaaaaagaa gatgacgatt cattcaaaaa tcgcattaac cgttacaggt acccttttat
    79501 taggcggatt cgttgtgttc tttttcacag agcgcaatgg ggcaacgcta gtggaaggga
    79561 atatgtttca acgattggca aacacctttt ttatgagtgt gacacctaga acggctggat
    79621 attattcagt tgattacctc catatgagcc atgcaggtct gattttaacg atgtttttga
    79681 tgtacatcgg cggaacatct gggtcgacgg ccggcggatt gaaaacaact acgttaggtg
    79741 tgttgctgat ccagatgcgt tcgatgttga aaggacgtac gagagcggaa gcatttggcc
    79801 gtaccatccg acaaggcgca gtgttgcggg cacttacttt attttttgtt acgttgacgt
    79861 tgtgtgtagt cgccatcatg attttatcgg tgactgaaac gatacctaaa acttctggca
    79921 tcgaatatat tgcttttgag gtcttctctg cgtttggtac agtaggtctt acgatgggat
    79981 tgacgccaga cttgactgca atagggaaat tgatcattat agcgcttatg tacattggac
    80041 gagttggtgt attgactgtg gtcttctctc tgatgacaaa agcacaaaga acacaatcaa
    80101 aatacaaata tccagaagaa agtgtcatga ttggataatt tcatcttctg acagaaacct
    80161 agtgatttag taaaataaga aaataaaata atttttcttg cttcttggat actttaagtg
    80221 caaaatgttc gtttattttt tgaggcacta cccgttgttg aacctcgggt agtgcctctt
    80281 ttttattgaa aggaatcaat aagatttgat tcctttattt atcaataggt tataattcat
    80341 atttttttat tttttctttt acgatactta gtccagaagc taaaatttca aggttattag
    80401 aggataggga aattcgaacg aatgcatctg gttgcgtacg tgtagtaaag cgtctggaat
    80461 gataaagtcg gataccgtta gcaagaaagt cattctcaat tatcttaggg tcaatctcag
    80521 gatcaactgg aagaattcga tagtaaggga cacgattcgt tggtttttct actttgaaaa
    80581 gagaatcaaa aagctgattg gctctttttg taagacttaa tttagtttct aagatcctat
    80641 ttgcttcatt tgaatggagg atttgagtga tgacttccac atctaatcca gaagttttca
    80701 catttatatt aaaaattgct tgttctatct tgctttggac atgtactgga actacaagat
    80761 aagcaactcg caatccagaa caaataaatt ttgtcattcc agctaagtag attgtttggt
    80821 taggtaataa attttggaaa ggaggaatga tcgtatgttg atagtaagtt gttaaaaatg
    80881 aatggatatc atcttcaata acccatagac cttctttttc aatcacttcg gctaattgct
    80941 ctcgtctttt gtgagagatt tgaaacccta taggattatt acaagaaggc ataagaaaga
    81001 caccatgaat cttctttttt ctacattcct gaatcaatat atcaggtcgc attccttgct
    81061 cgtcaaaatc aattggaacg atctctaaat gatataactg agccaattca atgaaattag
    81121 cgtatgtata tcggtctgtt gctattctat cacctggaga gaaaagtgca gaaagtgtga
    81181 tagccaatcc attttgaaca ccggaaacaa tagatagaga ttctaaggac ggaatgactc
    81241 cttgagtttt taaccaattt gctgcagtag tcaattgaaa atttgtgcct ttgggatctt
    81301 ggtaattaag caaaccaaca agatttgggt tattactagt tgattgaata aacgggacaa
    81361 cgaatttatt acattcttca aaagaactaa ccagaccaaa atcaatgata tgttcggtta
    81421 cttcattggt agagatggtg atggactcaa agacattggg agaaataaat gtgccacttc
    81481 caatattcgt atacagcaaa cctttctcaa ttccatattt ataagccttg ccaacggtag
    81541 taaaatttaa atctaaataa tcagctagct ctctttggga gggtaactga gtgtttttct
    81601 gtaatttatt ctttaaaata tcttgttcta attgttgaat caacgatcga taataaggac
    81661 gcttcaattt ttgtttgtct ggtcgccaag ttaacgggta attgtcataa gaattaatag
    81721 gcattttctc cactccttaa aattgtatac catacaattt taccattgat tgtattgatt
    81781 ttagaagtta atcttttgtg aggagggaat tgtctatgaa aattattaat tttgaggaag
    81841 tagtagcttc ttttagtttt gaagaagcga ttcaagtaat gaaaaaatgt ttttttgatt
    81901 atgaaagtgg taaaatcagc caaaatcctc gattggtgga aattttacct gacggaaaag
    81961 gcaaaaatat gtttgcgatg atgcctgctt atttggggga gaacagatat tttggcacaa
    82021 aagtcattac cgcttttccg gataatcatc agtatcattt accttctcat ttaggagaga
    82081 ttttcttgtt tgatgctcaa aacggactac ccaaagcatt gataaacgca aatgcagtca
    82141 cctggattcg aacagctgct gtatctgcgc tggcaacaga ttacttagca aatccgcatg
    82201 cagaaacact tgctttaatt ggagctggtc aacaagcatt gtcgcatttg actgcgattt
    82261 ctaccattcg tcccatcact acagtgtttg tttacgatat tttagaagaa agacgaaata
    82321 cttttatcgc taaagctaaa aaacagtatc ctaaaataac gtttataaat gcaatatcag
    82381 tagaagatgc agtacgtcca gcggaaatca tttgtacgtt gacctctagt aaagaggcat
    82441 ttcttcaaaa agagtgggta agggaagacg cacatatcaa tgctgtgggc acatttactc
    82501 ctgatacaag agagataagt acatcgttga tggaaacttc tcaaatctat gtagatgatt
    82561 actcagctgc cttaacagaa agcggggacc tgcttatagc catggcagaa ggagatttag
    82621 aggaatcttg tattgttggt acattaggcg aattagtttc tgagaaaaaa acattttata
    82681 aaggagaatc gaggccgacg attttcgacg cagttggtct agctattgaa gatctttgtt
    82741 gtgcagaata tatttataac aaattagaga aaggggcttt aaaatgaact tagattatta
    82801 cgtagttgat gcatttgcag atgaggtgtt caaaggaaat ccagcagcgg tttatgtgct
    82861 agaagaatgg ctgccagaag gtacgatgca aaaaattgcc attgaaaaca atttatctga
    82921 aacagcattt acagtgaaga aaaaccaaga atttgagctt agatggttta cgccagatcg
    82981 agaaatcgat ctttgtggtc acgcgacatt agcaacagca tttgttttat ttaactatta
    83041 caaaatacct gatgaaacga ttaaattttc tactcaaagc ggtaatctat ttgtgacaag
    83101 aattaaagat tattattaca tggattttcc tagtattatg ccgaaaaaag tgccgatatt
    83161 gtctgaatat gaagaagcga ttggggctaa gattaaagaa gcctacttag cacgtgattt
    83221 atttttcgta ttagaagatg aaaaaacggt ggctaaattg cagccagatt ttacagctat
    83281 caaaaatttt gaattaggaa taggagtcat cgtgacagca gaaagtgtgc aaaaagactt
    83341 tgtttctaga accttctttc caaaattaac aatcaatgaa gatccagtat gtggatcagc
    83401 acattctaat cttattcctt attgggcaga aagaatgaat aaaacaaaat tgtcagctta
    83461 tcaaatgtca tcaaggggcg gggatctaga atgtgaatta aaagaagatc gtgtgataat
    83521 aggaggaaaa gcagttttgt tttctaaagg tacctcgttt atttgatttc tttcaaatga
    83581 attaaaaata aattggtgga gagtggcaac cttatagcta caatggttgt taaaaaaaga
    83641 cgcaaacttt ttcaatttaa tgaaaagttt gcgtctcatt ttaattattg gtgtttgttt
    83701 tttattcaat caagagtaaa atgccccata ctaactatcc tcggatgact tcgattttat
    83761 aaccatcagg gtcaatgaca aagtagtaag aaggcgcagt gccaggtaat ccttttaagt
    83821 cagtaatctc aagaccagca gctttatgtt gctcgtgtaa tttttctaga tcatcagctg
    83881 ctatagcgat atgaccatag ccgtctccta gatcatacgc accatgatca tagttgtaag
    83941 tcaactctaa ttcatagtca tccccaggaa gtgtcaaata aacaagtgta aatttgtttt
    84001 ctggaaaatc acggcggcgg ctttcttcaa aaccaaatgc cttttgataa aattcgattg
    84061 atgcttcaag atctttcact cgaacacatg tgtgagccat tttcatagat tcatctctcc
    84121 ttttcctttt actcaatcat aacaaaaaga agtaaggaaa tagttgattt gtgcttgttc
    84181 atgagaaatt tctcatgtaa aatggataga aaataaaact gttaaggtgg aaactattca
    84241 tggataaacc aatttttggt gaaaaaaagc aatttgctga ttatcaaacc cgttatgcag
    84301 catatattgt catagaaaga gatcagcaga ttgcagtaat cgaggctcca aatggtgctt
    84361 tttttcttcc tggcggggaa attgaaggag aagagacgaa agaagaagcg attgtccgtg
    84421 agctgataga agaaatggga attgtggcag aaatttcttc ttatctggga gaagctgatg
    84481 agtattttta ctcgaattat cgtgcaactt attattataa tccaggatat ttctttgttg
    84541 ctgattcttg gaagcgtata ggagaaccaa ctgaaaagac caataaaatt tggtgggtga
    84601 gccctcaaga agcgcttgtg aaattgaaac gtggtagcca ccgatgggca gtcgagagat
    84661 ggatcgaaaa aaataaaaac tgaaagaaag cgagtagatc agctttctct cagttttttt
    84721 atttattaca gtacatattt tttgattgct tcagctacac cgtgctcgtc gtttgatgaa
    84781 gtgatgacat ttgctgcttc tttgacaaga gaaacggcat ttcccattgc tactcctaga
    84841 ccagcatatt caatcatgga taagtcgttc tcgttatctc cgatagccat gatttcatct
    84901 tgatcaatac caaggtgctg tgcgagattc gcaactgccg cacctttact tgcttcttta
    84961 tttagtactt cgaagtaata gggcgcactt ttgaccgttg tgtatttatc acggaaagtt
    85021 tgcggtaaac gcgcaattgc tgcatctaaa atttctggtt cgtcgatcat catcattttg
    85081 acgatgttca tgtctggtgt catttcttca ggtgttcgat attttagcgg catcttgact
    85141 aaacttgctt cgtggatcgt ataagcgctg atatctcgat taggcgtgta gatcgctttg
    85201 tcatcgatcg aatggagatg actgccgaca cggcgtgcca tcacttcgat ctctaggaaa
    85261 tcttcatgtg tcagtccgtg acgggcgatg attttacctg atttcgtttg ttgtacgagt
    85321 gccccgttat aagtaataac gtaatcatta tcttgaaaaa ggttcaactc gtttaactgt
    85381 tcctggacac ctggtaaggg acggccagtg cataaaacga tcgaaacacc ttttgcaaca
    85441 gcagcggcaa tcgcttcttt tacttctttt gttacttctc ttttctcatt taataaagta
    85501 ccatcgatgt cgatagcgac tagtttgata gacataattt cctccaatat attttaattt
    85561 atttcaatca atgcgccatt acggatatgg ctggcaaatt cttgataagt ttcgtcaaat
    85621 aaatcataat gatcacgcaa ggacggatca accatttctt ttggaaagaa aaatcgctca
    85681 tctccttgtt cttgtcccgc taatgcagca acaagctgac taacctgtga taattctatc
    85741 aaagttccgt catttcgcaa aatctcgatt tgtgtgcgat gtctgccttg ttctgggcga
    85801 taaaaatcat aaggtagatc gtagctagaa ttcacagcag tgtaataaac aggattatat
    85861 ccgacctttt ctactaacaa agtgagttct tggactaatt ttgaatcccg gttgccagaa
    85921 aaagtagcag atttcagtgg tttacgattc aaaaaacgtt tagctaaatc atttaaaata
    85981 ggatcagcag attcagacca ttgagtaaag taagtgccca agaccccatc atcaagtttg
    86041 aggtattctt ctaaagtaaa gcttccgtca agaaatggca gaagtaattg agaatggagt
    86101 tcaaaactgc tggcatcttc ttgatacaac tcgtgtgcgc gatgaagcag atgctccaaa
    86161 attacttcca taccacggga aacaggatgg aagtacactt gcacatacat ttgatatcgg
    86221 ctaacgatat aatcttccac tgcatgcatg ccactcatgg aaaaagcgat cccgccttca
    86281 taaggacgaa tcacacgtaa tattcgggta agatcaaatg ttccatattc tgttccagtg
    86341 aaataagcat cccgaagcaa atagtccatt cgatctgcat cgatctgact agaaatcatt
    86401 tggacaactt gtgggttggg gtaagttttt tggatcacac tagctacctt ttcaggaaaa
    86461 ccttcttcta ctcggttaag aatctgatac acttctgttt ctggagaagt gatgatctct
    86521 acagtgatgg cttcatgatt cgtatggaag atatgttcaa atgtatgaga gtaaggacca
    86581 tgaccgacat catgcaacag tgccgcacat aaagtcacca gccgttcctg atcatcccag
    86641 cctccgttgc ctattttttc ttttgaaaaa tttcgagaaa agatatcgca gattcgtctt
    86701 gaaatctcat aaacgcctaa tgaatgagta aaacggctat gttctgctcc gtgaaaagtg
    86761 aaagaagaag tgcctaattg tttaatgcgt cgtagacgtt ggacttcttt cgaattgatc
    86821 aaatctaaga ttacttgatg ctggacatgg atatagttat ggactggatc acgaaaaact
    86881 ttttccatag gcagcatttg atatttataa ggggttgtca taatgtagct cctttatgtt
    86941 attacgttgt tccattctct ggatttggtt gttccattgc tccagctgga tttctttttt
    87001 tagccagtcg gtagaatcct gtaaatcact tgcagaatac agcttttcaa aagcttttgc
    87061 aaatgcttct ttgacttctt ttacaaaaag gggttggtca agcagttctt caagtgttgc
    87121 cattgtagca ggatccactg caggatagcc atttgtacca aagtcttctt ttaaagcaga
    87181 ttgataaaat cgcttcatga cttgcccgcg tttttcctga ttaccgttga cacttaagta
    87241 catcataaca gaaatcccat ttttgatccg acgctgagcg ataccggcaa attttttgcc
    87301 atggatgctt aaatcataag ttccaggaca ataagaatgg gtgatttcga atgcttgtat
    87361 cggtgccttt ggaaaagcgt atttagtcaa taggagcatt tgctcgtaag cgtcatctat
    87421 ggttattttt tttgtgtcac tttgggggaa aatcaaagaa atattcaaaa ttccttcatc
    87481 tgatacgatc cctaatccac ctgaatttct gatcactgga gcgtaacctg catctttcag
    87541 tgtttggatc ccgtcactta gaaaaggagt tcgaacatcc ttcataccta agatgactgt
    87601 gcagtcatat tgccagaaat gtaaaaagat ttgctggtgt tctttagaat attccgttaa
    87661 tatatctgtt aatgcaaaag gggaaaagtc gtttttttga taaatgtgct gatctagtcg
    87721 aatcgcaggg ttcattcaac cggctccttt gtataaattc atattttcta caatattata
    87781 ctctaaaatc aaagagttgt tttggaaaaa aggttttctg taaaaatgga caagttggtt
    87841 gacaaaacaa aagaaactag gaacaatgta gctatgagaa gtaaaggaga atgaataatg
    87901 gaattatcac aaggaacacc gatttcaatc aaattgcgta caaaagtaaa acagcaaggg
    87961 gaagtgcaag atttttattt tgatttgaaa gggcaaatgg tgacaattgg cgatacgctg
    88021 tacatacgtt ataaagagat tcaggaggag acgggcgatg agattcctgt aacgatcaaa
    88081 ttagttccag atggtcatgt acagctgatc cgtgcaggag aaatgcggat gcgtttgaaa
    88141 tttggctata aagaacggtt agaaacatcc tatcgaacac catacggtat gatccagatt
    88201 gctactttta cgaaagaact gcatgttagt ttgaaagacc gtcccacagc agggaaggtt
    88261 cgaatcgatt atgatctgtt catgggaccg gaaaaaatcg gcgaatatta tttgaccttg
    88321 gattttacag cgtaaatata aaagaaaagt ttgatttttt gtgtctgatt ttgtatgata
    88381 aggagtagac tgtgaaagga cgtgtcctga ttggaaatta gtgtatttga aggtgcaaac
    88441 aaaagcgaat tatcaatgat cgaagtagca cacgcgatct tagaacaacg tggcgatgtc
    88501 atggattttt ctgatttagc taaccagatc caaaactatc ttgggaaatc agacagtgaa
    88561 attcgtgatt cactcgcaca attttatact gacttgaata ttgacggcag ctttatctca
    88621 ttaggggata atcgttgggg cttgcgttca tggtatgcta tcgattcgat cgatgaagaa
    88681 gtaaaccatg gaatggacga agaggatgaa gatactccac gtcgccgtaa acgcaagaaa
    88741 gtcaacgcct ttatcaatga tgatgaagac gcgatcgatt acaatgacga tgacccagaa
    88801 gatacagatc tgacagaaga agatgacgat gatctgtttg atgacgatga tgatgaagat
    88861 gaagaaatcg ctgcttataa ttctgacttg caagaaatcg gagcagatga cccgacagat
    88921 gatgaagaag acttgccagg aaatatcgaa gaagatttaa gtatcataga cgaagacgat
    88981 gatgatgaag attatgaaga ggaagaattt tctgactctg aaaaagaata aacattattt
    89041 tcttacgaga ggttgtgaca gagacgatca gcctatcaga ataaggaggt gtgacacgat
    89101 ttttgtcaca ccttcttttt tgtatataaa aatcccaagt aaatacataa aaaataaaaa
    89161 aattgaaact tttagcgcac cttgtacgtc atattaagtg aggcagaaag gagtggagaa
    89221 tgatttttac tggatataag aaaaaacggc agatcgaaaa ataccgtcac ctgctgaatg
    89281 gactcatcga aactgattat caaaaaatgt tccgtatcac gatgaattac gtacatgata
    89341 aagaagaggc cttagatgtg atgcaagata gttttcataa agccctgaac tattttgaaa
    89401 aagaaaaaga gatcgagcat tttagtgcat ggttttatcg gatattgatc cgcacggcat
    89461 tagatagttg gcgcagacaa aaaaggacgc ctgtggactt atttgaaatt caagatatcc
    89521 cccaacagtt acctttagaa acttccgttg cagagctcca tatgatttta gataaaatag
    89581 acagtccgga aaaagagatt ctgatcctct acttttttga aggatttcgt ttgaaagaaa
    89641 ttgcgactat cttggatatg aatgaaaaca cagttaaaac gaaaatgtac cgctcattga
    89701 atgctttacg tcaaatccta gaatgaagga gagaagagtg ccatgtattc ccaaaaagaa
    89761 aatttaaaaa aactaaagaa aacttataaa gaacaagcaa ttcccaaagg gcttaaagag
    89821 gagatccgcc agcgttttat tatcgaagag caatcattta taaaagcaaa gcggagaaag
    89881 agacgtctcc aagggttcgg agtatctttg gctatcgtaa tgattacaac aagtagcctt
    89941 ctttttaata gtcaagttcg aagctttgca gaagatttac ccatcttagg atcagtcatt
    90001 gaattgatct taggcgaacg ctttactgat cgatctgaaa aaatcgatat tcaggtaccg
    90061 aagatcaata cacaaaatga gaaagaaaat aaaacaattc atggattaaa tcaaaaatac
    90121 tttcgcgaag gacaagcaga ttttgaaaaa gctgaaaaag aatatggaaa ttttgaaacg
    90181 gatcattacc aagttttggg agattatcag aaaatcgtag acgataaccg gtttctcgtg
    90241 attgaaaggc agatcaccca aacagcagca gatagccatg ttgaaaaaag atacgacaca
    90301 atcgacaaga aaaacagtgt ccagctctca cttccacttt tattcaaaga tgacacctat
    90361 ctatctgttt tgacaaaaga agtcaaacgg cagatggccg aacaagtcaa ggaagatcca
    90421 tctaagtact attggactga gcaagatatt caagaaggga cgatagaaaa accaacactt
    90481 gttacgccta cacgaagttt ttatttgaac aaagagcatc aattagtttt gactttttct
    90541 caatacgaaa ttgctcctgg ttatatgggt acaccagaat ttgtcattcc taagtccgtg
    90601 acaaaaacga ttttggcatc ggaagattat ttggatcatt agacgagaag tagttgcgac
    90661 tagcagtttc aattttcaag taagtacaag taaataataa gaagagaaaa agagaaagaa
    90721 gagatatagt gaaaagaaat tatttagtta tcagtattat tgctttatcc gtgcttttgt
    90781 ttttcgaaat tacttcggtg gcctccttga tcaccgaagt aaaaggacaa acacactctt
    90841 cggagcattc gtcacaatct ttcaaacaat cagaacaatc aaccattaaa agccaatcaa
    90901 ctgaaacagc taacgtcaaa gaagccattc aagaatcagc ggaaaaggta caaagtcagt
    90961 catcacaatc aacacaagac agtacaaaaa cgagccgaga tccggctgtc aaaagcgtcg
    91021 caatcagctt tgatgatgga ccaggagcga ccacaacacc gcagcttctg cgaatcttaa
    91081 aagaaaaaaa cgtgcatgcc acttttttcg tcttaggaga aaatacggcg cagcatcctg
    91141 aaatcgtgaa gcagacagct gaagcagggc acgagattgg caatcacaca tacgatcatc
    91201 agaatctggc cactctttct gcccagtcga tgacggagga agtgacgaaa gcagacactg
    91261 agatcaaaaa agtcactggc aaaaccccca cttttgttcg tccgccctat ggttctgtca
    91321 cgaatgtagg agcaacgatc atccagcgac cgatcatcga atggtctgtt gattcagaag
    91381 attggaagac aagaaatcct gatttgattt tgcagaagat ccaagcaaca gtatacgatg
    91441 gggcaattat tttattccat gatatctatc ctgaaacgat tcgtgccgtt cctcaagtga
    91501 tcgattatct gaaagagcaa gggtatcgca tcacgacagt tggggattta ttagggcatc
    91561 caacggctgt cgagaactat tatggcagaa acgatcatcg gccagttcag taagtgagac
    91621 aagtatcttt aataaataac acattttaat aagtagttga acacataact accttacttg
    91681 caaaggctta acaatatcta tacaggtaca acaaaaaact gtccaccaat tttctttggc
    91741 ggacagtttt cacttaaaaa taaagaagca actattcgta aattatgcta aaatagcagt
    91801 agaacgcgtc ctgagggaat cgaacccccg tctcaagaac cggaatctta cgtgatatcc
    91861 actacactaa ggacgcaagc actgggataa ttgtaactaa acagataaaa aattacaagg
    91921 ggattggaca aaaaaatgaa atttgagcaa aatttttcac aaaaacagca gcagacacag
    91981 aaactagcca tgacgcaaca gttgcaacag tccatccaag ttttacaata taacagtgag
    92041 gagctgttgg cattcgttga gaatcaagca atggaaaatc cattggtgga agttgttgag
    92101 ccggaatggc agccagatta cataaaagct tcttcatctt cttatgaagg agaagagaca
    92161 aattacctaa atcagattcc tgatacaaaa gggtctttat ttgattcatt gatcgaacaa
    92221 gtccatttga attaccgaga tacttttttg aggaaaatcg ttctttatct tgtagaatac
    92281 atcgatttga acggattttt gacgattagt ttagaagaag ccggaaaaga gattggagct
    92341 acgcctatcc aaatgctcga tgcgttgact ctgattcagc aattagaacc agctggagta
    92401 ggtgcacgta gtttgcaaga atgtctcatg cttcaaacag aacgagatga ttatgcgccg
    92461 gaattagctt atatcgtgtt ggaagaatgt tttgaggaac tggtggagcg aaaatggaaa
    92521 gaaatcgcac aacgtttttc tgttgatcta catgctgttc agcagatatt cgactattta
    92581 caaacgttga gtccaagccc tggccggatt ttcgaccgta gcagcgaatt gtacattatt
    92641 cctgatgtcc gggtattagt ggacgacgat aaaaatgtac aagttatctc aaaccgaaaa
    92701 aatcagccaa atatacgctt tcaagagagt tacttcaaac aaatgtcaca acaagcagat
    92761 aaagaaactg aaaattattt aaaagaacgg aaacaggaat tcgaatggtt gaagaaaacg
    92821 atcctacaac gtggggatac aattttgcgg gttgctcaag tcattgtttc ccggcaaaaa
    92881 gctttcttta tcgacaagga acgtccaatc aagcctctta cgttaaagga agttgcaact
    92941 gagatagatg tgcatgaatc cacggtcagt cgtgcagtca acgggaaata tttggaaaca
    93001 gacttcggtg tatttgaatt aaaaaaattt ttcactacac gaattcctac gaatagtaca
    93061 gaacagacag aagacctttc agcagataca gcgaagaaaa agctgcagga attagtcgat
    93121 caagaagaca aaaacaagcc gttgtctgac cagaaattgg ttgaattgct gaaaaaagat
    93181 gagatagcga tctcaagacg aacagtagca aaatatcgtg atttattagg aatcccgagt
    93241 tcatcaaaaa gaaaacgtta tgataactaa tcagtcaaaa gactagaaaa agtatttcac
    93301 tttttctagt ctttttagtt gaaaaacgag agcaaaactg ttagacttac agtcgtgagg
    93361 ttgagatttc cctttattga tgtgaaattc gaatagttaa tttctttttt tatcgtatat
    93421 gggtcgtttt aagtctacat tggacgtaaa gtgtccaact aaggagatcg ctatgctgga
    93481 tgaaataaaa atgattgaat ctgttgcacc agatattatc gaagtgttgc aagaacgcta
    93541 taaaatttta cgaaatatct attggatgca gccgattgga cgtcgaagtt tatcggaaag
    93601 tatggggatc acagaacgag tattgcgaac agaaacagat cttttgaaaa atctgaattt
    93661 gatcgacacc tcaaaaagcg gtatgacgct gacaactaag ggcgaagaag tttatcaaag
    93721 ccttgaaaac ttcatggatc agcttttagg tacgcatcaa accgaacaac agttggcaga
    93781 atattttggt aaccaacgct gtatcgttgt ttcaggaaac agcgaagagc agaccaaagt
    93841 ggctgatgca ttcggcgaag cgctgagcga agccctagac cgactacttc cagaaggcga
    93901 gaatatcatc gctgtgatgg gaggaactac tatggctgtg gtagccgaac aattgtctaa
    93961 tctggaaaat aagaaacggc ataacctgtt tgtccctgca agaggcggga ttggtgaagc
    94021 gataactgta caggcaaatt ctgtcagtgc aagaatggct gctaaagcaa acggtaacca
    94081 ccgtgcactt tatgttccgg aacaattaag tctggcaact tacaattctt tactcaatga
    94141 gccatctatc caagaagtct taaacttgat tagtgaagcg aattgtgtta ttcatagtat
    94201 tgggcgtgca ttacacatgg cagcacgtcg taagatgact gaaaaagaat tagtcatgct
    94261 gaaacaagca aatgctgttg cggaatcttt tggctacttt ttcaatgaaa aaggtgaagt
    94321 cgtttataag gtccctagaa tcggcataga attgcaagat ttggaaaaag tcccgatcat
    94381 catggcaatc gcgggcggaa aatcaaaagc taaagcaatt cgagcttata tgaaaaatgc
    94441 accaaaacaa acgtggctca tcactgatga agctgctgca aatgagattt taaaaggggt
    94501 aaccctttaa aataaatatt tttttgattt tcataaggag gaaatcttaa atgacagtta
    94561 aagtaggtat taatggtttt ggacgtattg gacgtctagc attccgtcgt atccaagatg
    94621 tagatggaat cgaagtagta gcaatcaacg acttgacaga tgctaaaatg ttggcacact
    94681 tgttaaaata cgacacaact caaggacgtt tcaacggaac agttgaagtt catgaaggtt
    94741 cattcaacgt aaacggaaaa gaagttaaag tattagctaa ccgcaaccca gaagaattac
    94801 catggggcga actaggcgta gatatcgttc tagaatgtac tggtttcttc acttctaaat
    94861 cagcagctga aaaacattta acagctggtg ctaaacgcgt tgttatctct gctcctggcg
    94921 gaaacgatgt tccaacaatc gtttataaca caaaccacga aacattaact ggtaaagaaa
    94981 cagttatctc aggtgcttca tgtactacta actgtttagc tcctatggct aaaacattga
    95041 acgacaaatt tggtgttgtt gaaggattaa tgacaactat ccacgcttac acaggtgacc
    95101 aaatgactct agacggacct catcctaaag gtgacttccg ccgtgcacgc gctgctgctg
    95161 caaacatcgt tcctaactca acaggtgctg ctaaagctat cggtttagta attcctgaat
    95221 tgaacggtaa attagacgga gctgctcaac gtgttcctgt accaacaggt tcattaacag
    95281 aattagtaac agttcttgaa aaagaagtaa ctgttgacga aatcaatgca gcaatgaaag
    95341 aagcttcaaa cgaatcttac ggatacaaca cagacgaaat cgtttcttca gatatcgttg
    95401 gtatgactta cggttcatta tttgatgcta cacaaactaa agtaatgaca gttggcgaca
    95461 aacaattagt taaaactgtt gcttggtacg acaacgaaat gtcatacact gcacaattag
    95521 tacgtacttt agaatacttc gctaacttat aagatagaca aacgtacaag tgtaaattat
    95581 agacatgtac atttaaaagc ggggaagcaa tcgcgcttct tccgcttttt ttgataataa
    95641 gtttattcag gaggaaataa aatggctaag aaaacagtga aagatatcga tttaaaagac
    95701 aaaaaagttc ttgtccgtgt tgacttcaac gttcctttga aagacggcgt gatcactgac
    95761 gacactcgta tcaaagcagc attgccaaca atcaactacg ttctagaaca aggcggaaaa
    95821 gcaatccttt tctctcacct tggacgtgta aaaacagaag aagataaaga aggaaaatct
    95881 ttagctccag ttgcaaaacg tctaggcgaa ttattaggta aagaagtaac attcgtacct
    95941 gaaactcgcg gagaacaatt agaagaagca atccgcaaca tgaatgacgg cgacgttgtc
    96001 gtattcgaaa atacacgatt tgaagatatt gacggtaaaa aagaaagcaa aaatgataca
    96061 gaactaggta aatactgggc ttcattaggc gatgtatttg ttaacgatgc tttcggtaca
    96121 gctcaccgtg cacatgcttc taacgtaggt atcgcttcaa ctggtatccc aacagttgct
    96181 ggattcttga tggaaaaaga aatcaagttc atcggtgaag cagtagaaga accaaaacga
    96241 ccaatgattg caatccttgg tggcgcaaaa gtttctgata aaatcggcgt aatcgaaaac
    96301 ttgattccta aagcagataa aatcttgatc ggtggcggaa tgacttacac attctacgaa
    96361 gcaaaaggaa tcaagatcgg taactctcta gtagaagctg ataaagtgga actagcaaaa
    96421 gaattaatcg aaaaagcagg cgacaaactt gtcttgccaa tcgacaatgt ctgtgcacca
    96481 gaattttcaa atgatgttga aacacaagta atcgaaggag acattcctga tggtttgatg
    96541 gctttagaca tcggcccagc atcagtaaaa ttatttgctg atacattaca aggtgcaaaa
    96601 acagttgttt ggaacggacc tatgggtgta tttgaaatga gtaactttgc taaaggtaca
    96661 atcggtgttt gtgaagcaat cgctaactta gaaggcgcaa caacaatcat cggtggcgga
    96721 gactcagccg cagcagcaga acaattagga tttgctgaca aattcacaca catctcaaca
    96781 ggtggcggcg caagcttgga attgcttgaa ggtaaagaat taccaggact agcagcaatc
    96841 aacgataaat aaacgaccaa gtttgctcaa ttctgacgag taatcgaaca aaaggtgaag
    96901 ggagttttca tgactcccta gccatttttc aataaattaa ggagtgtgtt cctcaatgcg
    96961 taaacctatt atcgcaggta actggaaaat gaacaaaact gcatcagaag caaaagaatt
    97021 tgctgaagca gtaaaaaaca aaatcccttc aaatgacaaa gttgattcag tcatcggatc
    97081 tcctgcatta ttcttacaag aattaatgac atcagctgaa ggtacagaac taaaaatctc
    97141 agcacaaaac tgctactggg aaaactcagg tgcgttcact ggtgaaactt caccagcagc
    97201 tcttgctgat ctaggtgttc attatgtgat catcggacat tcagaacgtc gtgaatattt
    97261 ccatgaaaca gacgaagaca tcaataaaaa agcgaaagct atctttgcaa atggtatgac
    97321 accaatccta tgctgtggcg aatctttaga aacctatgaa gcaggcaaaa ctgctgaatg
    97381 gatcgaagga caaattacag ctggtttagc tgatctttca gctgaacagg tgtcaaacat
    97441 ggttattgct tatgaaccaa tctgggcaat cggtactggt aaatcagctg acgcacaaat
    97501 cgctgacgaa atttgtggag ttgtacgtca aacagttgaa aaactttatg gaaaagaagt
    97561 atcagaagca gttcgtatcc aatacggcgg ttctgtaaaa ccagaaaata ttgctgaata
    97621 catggcaaaa gaaaatgttg acggtgcttt agtcggtggc gcaagcttgc aagcagattc
    97681 attcttgtca ttgttagacg ctgtaaaata attgttgaaa atttgcgaaa aatgcaagaa
    97741 atgtttgcac taatgagcaa aattaactaa aatcgtatat gagggaaatc ccttaggaaa
    97801 aaacaaactc aaaggagaga caaaacatgt caattattac tgatgtttac gctcgcgaga
    97861 tcttagactc acgtggtaac ccaacaatcg aagtagaagt atacacagaa agcggagctt
    97921 ttggccgcgg aatggttcct tcaggtgctt caactggtga atacgaagca gttgaattac
    97981 gtgacggaga caaagctcgt tatggcggta aaggtgtaac taaagctgtc gacaacgtaa
    98041 acaacatcat tgctgaagca atcattggct acgatgttcg tgaccaaatg gctatcgaca
    98101 aagctatgat cgctttagac ggaactccta acaaaggtaa attaggtgcg aacgctattt
    98161 taggtgtttc tatcgctgtt gcacgtgcag ctgctgacta cctagaagta cctttatacc
    98221 actacctagg cggattcaac acaaaagtat tgccaacacc aatgatgaac atcatcaacg
    98281 gcggatcaca tgctgataac tcaatcgact tccaagaatt catgatcatg cctgttggcg
    98341 ctccaacatt caaagaagct ctacgtatgg gtgctgaagt attccacgca ttagcttcaa
    98401 tcttgaaagc tcgcggatta gcaacttctg ttggtgacga aggtggattt gctccaaacc
    98461 ttggttcaaa cgaagaaggt tttgaagtaa tcatcgaagc aatcgaaaaa gctggctatg
    98521 tacctggtaa agacgttgtt cttgctatgg atgctgcttc ttcagaattc tacgacaaag
    98581 aaaaaggtgt ttacgtacta gctgattcag gcgaaggcga aaaaacaact gacgaaatga
    98641 tcaaattcta cgaagaatta gtttctaaat atccaatcat ctcaatcgaa gacggattag
    98701 acgaaaacga ctgggacgga ttcaagaaat taactgacgt attaggcgac aaagttcaat
    98761 tagttggtga cgacttgttc gtaacaaaca ctcaaaaatt atctgaaggt atcgaaaaag
    98821 gaattgctaa ctcaatcctt atcaaagtga accaaatcgg tacattaaca gaaactttcg
    98881 aagctatcga aatggctaaa gaagctggct acacagcagt tgtatctcac cgttctggtg
    98941 aaacagaaga ttcaacaatc tctgatatcg ctgttgcaac aaacgctggc caaatcaaaa
    99001 ctggttctct atcacgtact gaccgtattg ctaaatacaa ccaattacta cgtatcgaag
    99061 accaacttgg tgaagttgca gaatacaaag gtttgaaatc tttctacaac ttaaaaaaca
    99121 aataattctt ttctaatgaa gatacatgat cgactattga aagatagtcg agtatgatca
    99181 cttagttaag taatcgaact ctctacttgc tgaaatatca gcaggtagag agtttttttg
    99241 caactagctt ctgtatatga tgtttacaaa gaatggtaca agaaaagatc atccttgaaa
    99301 aaggaaagct aacaataact agcatcatat aagagctttt aaggatagaa cagtagaata
    99361 ggaatctatg agcaagtcct ctcgtataaa taaaatagga gggaagtagc agcatatttt
    99421 tcataaagtg gctctctttc ttcattttta ctttggttgc tcctatttga aaattcgagc
    99481 acactcaaat acaataaaaa gaaatggcaa gggagaggat tagatgaaaa aagaagaaaa
    99541 aatcgcgatt ttacaagaga tcatccgaat taaatcagtg aatggaaacg aaggtgaagt
    99601 agcagcctat ttgaataagc ttttggcaaa gcatgacata acaggagaga ttgtttctta
    99661 cagagatggt agagataatt tgattgctcg ttaccaaaag ggccaatcag gaaaagtgtt
    99721 aggcctatct gggcatatgg atgtcgtggc ggctggtgat gaatcgtctt ggacctatgc
    99781 accctttgca gcagaaatcc atgggaaccg tttgtacgga cgtggtgcta cagatatgaa
    99841 gagtggcttg gcagcaatgg tgattgccat gatcgaactg aaagagtcag gaaaaccatt
    99901 taacggaaca gtcaaattat tagccactgt cggagaagaa gtgggtgaac taggtgggga
    99961 acagctcacg aaagcaggct atgtagatga cttagatgcc ttgatcatcg gagagccaac
   100021 caattacagt ttgatgtata cgcacatggg atcaatcaac tatacagtca cctcgcacgg
   100081 aaaagaagcg catagctcta tgccagacca aggttataat gcaatcaatc acctaaatga
   100141 attcattacg aaagcaaatg ctgaaatgaa tcacctcgct gaaacaatcg agaatcctgt
   100201 cctaggaaaa acaatccata atgttacatt gatcagtggc gggaatcaag tcaacagcat
   100261 cccaagccat gcgcagctcc aagggaacat tcgatcgatt ccagaatacc caaatgataa
   100321 aatcattgca ttgctgcaat caatcgtcaa tgaattgaat caagagacag actatcattt
   100381 ggaattgatg atcgattaca acaaaatacc tgtcaaagct gatccagatt ctcctttgat
   100441 tcattgcatt cagcaacaat tcagccagcc attaccttta gttggagcgg cagcaacaac
   100501 ggatgcagcc gaatttacga aagctaacca ttccttcgac tttgtcgtct ttgggcctgg
   100561 tgtcgttact ttgcctcatc aagtagatga gtatgttgaa atcgataatt atttggatat
   100621 gatcgaaaaa tatcaaggaa ttattttatc ctacttagcg taagattttt ttaataaatg
   100681 aaaaaacaga gccagattag cattatt
//
LOCUS       DAFLVO010000002        84948 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.002, whole genome shotgun sequence.
ACCESSION   DAFLVO010000002 DAFLVO010000000
VERSION     DAFLVO010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 84948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.002"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            17..535
                     /locus_tag="L1U99_000102"
     CDS             17..535
                     /locus_tag="L1U99_000102"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBN1210680.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            663..1346
                     /locus_tag="L1U99_000103"
     CDS             663..1346
                     /locus_tag="L1U99_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBN1210681.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1655..1728
                     /locus_tag="L1U99_000104"
     tRNA            1655..1728
                     /locus_tag="L1U99_000104"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1689..1691,aa:Arg,seq:tct)
     gene            1887..2246
                     /locus_tag="L1U99_000105"
     CDS             1887..2246
                     /locus_tag="L1U99_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HBN1210682.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2369..4000
                     /locus_tag="L1U99_000106"
     CDS             2369..4000
                     /locus_tag="L1U99_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HBN1210683.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQFPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4062..4703)
                     /locus_tag="L1U99_000107"
     CDS             complement(4062..4703)
                     /locus_tag="L1U99_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBN1210684.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    4889..4965
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            4985..5293
                     /gene="rplU"
                     /locus_tag="L1U99_000108"
     CDS             4985..5293
                     /gene="rplU"
                     /locus_tag="L1U99_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBN1210685.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5320..5664
                     /locus_tag="L1U99_000109"
     CDS             5320..5664
                     /locus_tag="L1U99_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBN1210686.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5677..5970
                     /gene="rpmA"
                     /locus_tag="L1U99_000110"
     CDS             5677..5970
                     /gene="rpmA"
                     /locus_tag="L1U99_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBN1210687.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6404..9211
                     /locus_tag="L1U99_000111"
     CDS             6404..9211
                     /locus_tag="L1U99_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1210688.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            9402..9893
                     /locus_tag="L1U99_000112"
     CDS             9402..9893
                     /locus_tag="L1U99_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1210689.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            9996..10985
                     /gene="manX"
                     /locus_tag="L1U99_000113"
     CDS             9996..10985
                     /gene="manX"
                     /locus_tag="L1U99_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HBN1210690.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11018..11821
                     /locus_tag="L1U99_000114"
     CDS             11018..11821
                     /locus_tag="L1U99_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HBN1210691.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            11842..12756
                     /locus_tag="L1U99_000115"
     CDS             11842..12756
                     /locus_tag="L1U99_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HBN1210692.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            12839..13213
                     /locus_tag="L1U99_000116"
     CDS             12839..13213
                     /locus_tag="L1U99_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HBN1210693.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13352..13597
                     /locus_tag="L1U99_000117"
     CDS             13352..13597
                     /locus_tag="L1U99_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBN1210694.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13769..14833
                     /locus_tag="L1U99_000118"
     CDS             13769..14833
                     /locus_tag="L1U99_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBN1210695.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15079..15504
                     /locus_tag="L1U99_000119"
     CDS             15079..15504
                     /locus_tag="L1U99_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBN1210696.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15497..15946
                     /gene="nusB"
                     /locus_tag="L1U99_000120"
     CDS             15497..15946
                     /gene="nusB"
                     /locus_tag="L1U99_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBN1210697.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            16043..16897
                     /locus_tag="L1U99_000121"
     CDS             16043..16897
                     /locus_tag="L1U99_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HBN1210698.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            16898..18235
                     /locus_tag="L1U99_000122"
     CDS             16898..18235
                     /locus_tag="L1U99_000122"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBN1210699.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            18240..18464
                     /locus_tag="L1U99_000123"
     CDS             18240..18464
                     /locus_tag="L1U99_000123"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBN1210700.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            18466..19356
                     /locus_tag="L1U99_000124"
     CDS             18466..19356
                     /locus_tag="L1U99_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBN1210701.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            19365..20183
                     /locus_tag="L1U99_000125"
     CDS             19365..20183
                     /locus_tag="L1U99_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HBN1210702.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            20290..20739
                     /locus_tag="L1U99_000126"
     CDS             20290..20739
                     /locus_tag="L1U99_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBN1210703.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            20757..22439
                     /gene="recN"
                     /locus_tag="L1U99_000127"
     CDS             20757..22439
                     /gene="recN"
                     /locus_tag="L1U99_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBN1210704.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(22494..22610)
                     /locus_tag="L1U99_000128"
     CDS             complement(22494..22610)
                     /locus_tag="L1U99_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HBN1210705.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(22683..23639)
                     /locus_tag="L1U99_000129"
     CDS             complement(22683..23639)
                     /locus_tag="L1U99_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBN1210706.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            23810..24178
                     /locus_tag="L1U99_000130"
     CDS             23810..24178
                     /locus_tag="L1U99_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HBN1210707.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            24348..24779
                     /gene="mraZ"
                     /locus_tag="L1U99_000131"
     CDS             24348..24779
                     /gene="mraZ"
                     /locus_tag="L1U99_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HBN1210708.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            24800..25759
                     /gene="rsmH"
                     /locus_tag="L1U99_000132"
     CDS             24800..25759
                     /gene="rsmH"
                     /locus_tag="L1U99_000132"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBN1210709.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            25764..26165
                     /gene="ftsL"
                     /locus_tag="L1U99_000133"
     CDS             25764..26165
                     /gene="ftsL"
                     /locus_tag="L1U99_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBN1210710.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            26166..28358
                     /locus_tag="L1U99_000134"
     CDS             26166..28358
                     /locus_tag="L1U99_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBN1210711.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            28384..29346
                     /locus_tag="L1U99_000135"
     CDS             28384..29346
                     /locus_tag="L1U99_000135"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBN1210712.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            29360..30721
                     /locus_tag="L1U99_000136"
     CDS             29360..30721
                     /locus_tag="L1U99_000136"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBN1210713.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            30747..31835
                     /gene="murG"
                     /locus_tag="L1U99_000137"
     CDS             30747..31835
                     /gene="murG"
                     /locus_tag="L1U99_000137"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBN1210714.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            31850..33070
                     /locus_tag="L1U99_000138"
     CDS             31850..33070
                     /locus_tag="L1U99_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HBN1210715.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            33226..34551
                     /gene="ftsA"
                     /locus_tag="L1U99_000139"
     CDS             33226..34551
                     /gene="ftsA"
                     /locus_tag="L1U99_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HBN1210716.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            34574..35815
                     /gene="ftsZ"
                     /locus_tag="L1U99_000140"
     CDS             34574..35815
                     /gene="ftsZ"
                     /locus_tag="L1U99_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBN1210717.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            35832..36509
                     /locus_tag="L1U99_000141"
     CDS             35832..36509
                     /locus_tag="L1U99_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBN1210718.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            36523..37122
                     /locus_tag="L1U99_000142"
     CDS             36523..37122
                     /locus_tag="L1U99_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBN1210719.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            37137..37424
                     /locus_tag="L1U99_000143"
     CDS             37137..37424
                     /locus_tag="L1U99_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBN1210720.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            37473..38255
                     /locus_tag="L1U99_000144"
     CDS             37473..38255
                     /locus_tag="L1U99_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBN1210721.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            38276..38983
                     /locus_tag="L1U99_000145"
     CDS             38276..38983
                     /locus_tag="L1U99_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBN1210722.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            39245..42043
                     /gene="ileS"
                     /locus_tag="L1U99_000146"
     CDS             39245..42043
                     /gene="ileS"
                     /locus_tag="L1U99_000146"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBN1210723.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(42092..43618)
                     /locus_tag="L1U99_000147"
     CDS             complement(42092..43618)
                     /locus_tag="L1U99_000147"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HBN1210724.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(43633..44280)
                     /locus_tag="L1U99_000148"
     CDS             complement(43633..44280)
                     /locus_tag="L1U99_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HBN1210725.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(44464..44793)
                     /locus_tag="L1U99_000149"
     CDS             complement(44464..44793)
                     /locus_tag="L1U99_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HBN1210726.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            44970..45698
                     /gene="sfsA"
                     /locus_tag="L1U99_000150"
     CDS             44970..45698
                     /gene="sfsA"
                     /locus_tag="L1U99_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HBN1210727.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            45714..46727
                     /locus_tag="L1U99_000151"
     CDS             45714..46727
                     /locus_tag="L1U99_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1210728.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            46727..48004
                     /locus_tag="L1U99_000152"
     CDS             46727..48004
                     /locus_tag="L1U99_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBN1210729.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            48067..50769
                     /locus_tag="L1U99_000153"
     CDS             48067..50769
                     /locus_tag="L1U99_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1210730.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            50921..51238
                     /locus_tag="L1U99_000154"
     CDS             50921..51238
                     /locus_tag="L1U99_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1210731.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            51268..51588
                     /locus_tag="L1U99_000155"
     CDS             51268..51588
                     /locus_tag="L1U99_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBN1210732.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            51696..53156
                     /locus_tag="L1U99_000156"
     CDS             51696..53156
                     /locus_tag="L1U99_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1210733.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            53224..53445
                     /locus_tag="L1U99_000157"
     CDS             53224..53445
                     /locus_tag="L1U99_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210734.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            53476..53658
                     /locus_tag="L1U99_000158"
     CDS             53476..53658
                     /locus_tag="L1U99_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HBN1210735.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            53658..54071
                     /locus_tag="L1U99_000159"
     CDS             53658..54071
                     /locus_tag="L1U99_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBN1210736.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            54194..55375
                     /locus_tag="L1U99_000160"
     CDS             54194..55375
                     /locus_tag="L1U99_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1210737.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(55446..55610)
                     /locus_tag="L1U99_000161"
     CDS             complement(55446..55610)
                     /locus_tag="L1U99_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210738.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            55764..55837
                     /locus_tag="L1U99_000162"
     tRNA            55764..55837
                     /locus_tag="L1U99_000162"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:55798..55800,aa:Arg,seq:cct)
     gene            complement(55906..57045)
                     /locus_tag="L1U99_000163"
     CDS             complement(55906..57045)
                     /locus_tag="L1U99_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1210739.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(57344..57979)
                     /locus_tag="L1U99_000164"
     CDS             complement(57344..57979)
                     /locus_tag="L1U99_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210740.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(58092..58727)
                     /locus_tag="L1U99_000165"
     CDS             complement(58092..58727)
                     /locus_tag="L1U99_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HBN1210741.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(58761..59222)
                     /locus_tag="L1U99_000166"
     CDS             complement(58761..59222)
                     /locus_tag="L1U99_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBN1210742.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(59352..59783)
                     /locus_tag="L1U99_000167"
     CDS             complement(59352..59783)
                     /locus_tag="L1U99_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBN1210743.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(59801..60121)
                     /locus_tag="L1U99_000168"
     CDS             complement(59801..60121)
                     /locus_tag="L1U99_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1210744.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            60420..61196
                     /locus_tag="L1U99_000169"
     CDS             60420..61196
                     /locus_tag="L1U99_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBN1210745.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            61211..61414
                     /locus_tag="L1U99_000170"
     CDS             61211..61414
                     /locus_tag="L1U99_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1210746.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            61430..61768
                     /locus_tag="L1U99_000171"
     CDS             61430..61768
                     /locus_tag="L1U99_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HBN1210747.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            61755..61934
                     /locus_tag="L1U99_000172"
     CDS             61755..61934
                     /locus_tag="L1U99_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210748.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(61977..62447)
                     /locus_tag="L1U99_000173"
     CDS             complement(61977..62447)
                     /locus_tag="L1U99_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210749.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            62534..63232
                     /locus_tag="L1U99_000174"
     CDS             62534..63232
                     /locus_tag="L1U99_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HBN1210750.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            63410..63751
                     /locus_tag="L1U99_000175"
     CDS             63410..63751
                     /locus_tag="L1U99_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210751.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            63744..64415
                     /locus_tag="L1U99_000176"
     CDS             63744..64415
                     /locus_tag="L1U99_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBN1210752.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            64421..65113
                     /locus_tag="L1U99_000177"
     CDS             64421..65113
                     /locus_tag="L1U99_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210753.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGGEK"
     gene            65110..65859
                     /locus_tag="L1U99_000178"
     CDS             65110..65859
                     /locus_tag="L1U99_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1210754.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            65871..66140
                     /locus_tag="L1U99_000179"
     CDS             65871..66140
                     /locus_tag="L1U99_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210755.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            66146..66310
                     /locus_tag="L1U99_000180"
     CDS             66146..66310
                     /locus_tag="L1U99_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210756.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            66303..66602
                     /locus_tag="L1U99_000181"
     CDS             66303..66602
                     /locus_tag="L1U99_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210757.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            66602..66904
                     /locus_tag="L1U99_000182"
     CDS             66602..66904
                     /locus_tag="L1U99_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBN1210758.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            66944..67309
                     /locus_tag="L1U99_000183"
     CDS             66944..67309
                     /locus_tag="L1U99_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210759.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            67799..67939
                     /locus_tag="L1U99_000184"
     CDS             67799..67939
                     /locus_tag="L1U99_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210760.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            67936..68118
                     /locus_tag="L1U99_000185"
     CDS             67936..68118
                     /locus_tag="L1U99_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210761.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKI"
     gene            68131..68325
                     /locus_tag="L1U99_000186"
     CDS             68131..68325
                     /locus_tag="L1U99_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210762.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(68358..68570)
                     /locus_tag="L1U99_000187"
     CDS             complement(68358..68570)
                     /locus_tag="L1U99_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210763.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            68695..68898
                     /locus_tag="L1U99_000188"
     CDS             68695..68898
                     /locus_tag="L1U99_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210764.1"
                     /translation="MVKVREQFKIVSDEGNVYKIKIVNINEYREADHKYLVDLYMNDK
                     YLGEGFCGDSLFDDERILKEETE"
     gene            68895..69167
                     /locus_tag="L1U99_000189"
     CDS             68895..69167
                     /locus_tag="L1U99_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HBN1210765.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            69168..69353
                     /locus_tag="L1U99_000190"
     CDS             69168..69353
                     /locus_tag="L1U99_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210766.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            69340..69687
                     /locus_tag="L1U99_000191"
     CDS             69340..69687
                     /locus_tag="L1U99_000191"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210767.1"
                     /translation="MNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVLKIE
                     QNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIRGGV
                     CEISLVKRLPRTR"
     gene            69647..70123
                     /locus_tag="L1U99_000192"
     CDS             69647..70123
                     /locus_tag="L1U99_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HBN1210768.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(70254..70982)
                     /locus_tag="L1U99_000193"
     CDS             complement(70254..70982)
                     /locus_tag="L1U99_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HBN1210769.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            71030..71308
                     /locus_tag="L1U99_000194"
     CDS             71030..71308
                     /locus_tag="L1U99_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210770.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            71310..71696
                     /locus_tag="L1U99_000195"
     CDS             71310..71696
                     /locus_tag="L1U99_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210771.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            71693..72073
                     /locus_tag="L1U99_000196"
     CDS             71693..72073
                     /locus_tag="L1U99_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBN1210772.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            72185..72637
                     /locus_tag="L1U99_000197"
     CDS             72185..72637
                     /locus_tag="L1U99_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HBN1210773.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            72634..74361
                     /locus_tag="L1U99_000198"
     CDS             72634..74361
                     /locus_tag="L1U99_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBN1210774.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            74425..75612
                     /locus_tag="L1U99_000199"
     CDS             74425..75612
                     /locus_tag="L1U99_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBN1210775.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            75584..76153
                     /locus_tag="L1U99_000200"
     CDS             75584..76153
                     /locus_tag="L1U99_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HBN1210776.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            76166..77530
                     /locus_tag="L1U99_000201"
     CDS             76166..77530
                     /locus_tag="L1U99_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBN1210777.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            77532..77810
                     /locus_tag="L1U99_000202"
     CDS             77532..77810
                     /locus_tag="L1U99_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBN1210778.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETD"
     gene            77791..78117
                     /locus_tag="L1U99_000203"
     CDS             77791..78117
                     /locus_tag="L1U99_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBN1210779.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            78107..78445
                     /locus_tag="L1U99_000204"
     CDS             78107..78445
                     /locus_tag="L1U99_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210780.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            78435..78800
                     /locus_tag="L1U99_000205"
     CDS             78435..78800
                     /locus_tag="L1U99_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBN1210781.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            78807..79433
                     /locus_tag="L1U99_000206"
     CDS             78807..79433
                     /locus_tag="L1U99_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1210782.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            79433..79897
                     /locus_tag="L1U99_000207"
     CDS             79433..79897
                     /locus_tag="L1U99_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210783.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            80092..82401
                     /locus_tag="L1U99_000208"
     CDS             80092..82401
                     /locus_tag="L1U99_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBN1210784.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            82413..83117
                     /locus_tag="L1U99_000209"
     CDS             82413..83117
                     /locus_tag="L1U99_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1210785.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            83114..>84948
                     /locus_tag="L1U99_000210"
     CDS             83114..>84948
                     /locus_tag="L1U99_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1210786.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWR"
BASE COUNT        28620 a        13991 c        17851 g        24486 t
ORIGIN      
        1 aaagaagttg aaaacgatac ctgattacaa aaaaataact tttataagtt ctataacgtt
       61 gattatattt ttaattctta ttcttctcgt cgtcttggtt ccccgaattt ttggtttgac
      121 tccttatatt attgaggaca aagaaatgag tccatattat gcacaaggaa atctgatata
      181 tgtacgaccg aaaaatacaa atgagatttt agtcggagat attattacat attatgaaaa
      241 ttcaggaaaa aaaatctcga cgcgtcgcgt aatagccgtt gaaaacaacc acgaagattt
      301 ttatacaaaa gctgatacaa agacttatat tgagcctgga gtagtaaaaa agagaaatat
      361 tatcggtagt cccatctttc agattccata tattggacta gtcctttcaa aaacggcatt
      421 tgcatggatt caggggttat tctttacgat tgctttttgc ctaacaggaa tcacagcatg
      481 gaataccttt gtagagttga aaaagaagcg gagacgaaca cagaaatttt tgtaagaatg
      541 ttaaaaacat aaatgtattc cagagatcca acgactcttc tgaacatgaa acacgagaaa
      601 acactcatgc agcttgtaga tttagtcagt tgttcgtata atgtgtgaag aggaggagta
      661 gtatgcgcaa tgaaatgatg catcgtcctg tagtcaaaga agaactattg gattttatgc
      721 gtacccagca aaaaaaatta ccgggtgagc taggcaaact ggaagaagaa gctcatgtag
      781 cagaagtacc agttattccc catgaaacag ttgtattttt gaaattttta cttggacagc
      841 ttcagcctga acgaatcttg gagatcggag cagctatcgg tttttcatca agtgtcatgg
      901 ccacgacaat cggagaaaac gctcatgtta cgacaattga tcgtttcgat gtcatgatcg
      961 agaaagctaa aaaaaactat gaacgtctag gactgacaga taaagtgact ttgcttgaag
     1021 gtcaagcagc agatatcttg ccggagttgt ctggtccgta tgactttatt tttatggata
     1081 gtgcaaaatc aaaatatatt gaatttttac ctgaatgctt acgtttgtta agaaaaggtg
     1141 gcgttttgat ggtagatgac atcttccaag gaggaacgat cttgctccca gatgaagaga
     1201 ttccccgtgg caaacgagct atccatcgta aattaaatga atttcttcgt gttgtgatgg
     1261 atcatcccga tttgacatcg acaatcttgc cattaggtga tggtgtgatc ttaatgacaa
     1321 aggaatcaga aacaatcgag ttgtgataca tgattatggc agcctgtaga taatcgattg
     1381 aatcgagggc tcaattcgaa cttgatgtaa aagtttctat atttgtaagt caattaaagg
     1441 atacaggaaa tctaaataaa caggagtagc atgaagtcaa tgtagctcct gttttcaatt
     1501 gataacctta gaacagctga aggagaatgt ctcgttttaa aagattgatt tagtagttgg
     1561 gccaaaataa ttcattattt gctaattaaa taactatttc gtattgacag aagcaattta
     1621 attatctata attattgatg ttccgctgat tcttgtcata gtagctcagc tggatagagc
     1681 atccgccttc taagcggacg gtcgggggtt cgaatccctc ctgtgacgct aaaaaaccgt
     1741 tagaaactga ggtttctaac ggtttttctt tgttttttgt gccaatattg tttgttttca
     1801 aaggcaaata aaataaaaaa acatccttat cgagtacaat tataaggagc aaaaaaataa
     1861 aactcatcag aaaagaggaa gaagatatga cgatactatc tagaatttta gtgactctag
     1921 ttgcaattga atttttttat atcatgtata tcgaaacggt gagaactgat tctgacacga
     1981 caagtagggt ttttaaaatg agtaaagaag agttaagcag aaaatctgtt caaacattgt
     2041 ttaagaacca aggagtgtac aatggactat taggagtggg actactttat ggagcttatc
     2101 tttcttccgc atctaaagaa atcacaagta tgctattaat atctattttt tttgttgcat
     2161 tatatggcag tttgactagc gatcgttgga ttttactcaa acaaggtggg ctagctctgt
     2221 tggcattgct ttctattttc ttataaatat agaaaaaata agaatttatc taacaggaaa
     2281 ctttgtgaaa aatattactt tatctcatga aatatgatat tctaatgaat ggtattttag
     2341 aaaatttcat gaaaaaggag ttagataggt gttcaaaaat tatgtttcct cactaaaaaa
     2401 agaattttca ggttatgatc tttcaagatt tcagaaagat cttttggctg ggatcacagt
     2461 agctgctgta gcattgcctt tagccttggc ttttggggta tcaagcggag ctgatgcggc
     2521 cgcaggtttg attacggcta tcattgccgg tatcgttatt ggcggtttat caggcggttt
     2581 ttatcaaata tcaggtccga caggtgcgat ggcagctatc ttgatgtcta ttgcggcaac
     2641 aaagggaatg caaggtgtat tgcttgctac ttttttagcg ggtctatttt tacttgcagc
     2701 aggacttttc cgattaggaa cactgacttc ttttatccca gcacccgtaa ttacggggtt
     2761 tacttcaggt attgctatca ttattgcatt aggtcagatc gataatttat ttggtgttca
     2821 ctcggaaggt acaaacgtta ttgaaaaact aagtagttat caaacgatag gatttccgat
     2881 aaacacagcc tctttgatca tgggagggct agtcatttta gggatgttta tctatccaaa
     2941 aaaatgggcg aaacgaatgc ctagttcgct gctggctatc attttggcaa cagcagttat
     3001 gctattgttc catttaccag tagcaactgt gggtaagatt ccacaaacat tgatcagtag
     3061 taatcgtttg aatatgggag attttagctt ttctgccttg caacaagtgg cagttccagc
     3121 tattagcatt gctttattag gaatgattga aagcttgcta tgtggtgctt cggctggccg
     3181 aatggcaaat aagcccttag atagcaatca agaattaatg gcgcaaggaa ttggaaatct
     3241 gttgcttcct ttctttggcg ggattcctgc tactgcggcc atcgcccgta caagcgtggc
     3301 catcaaatct ggtgcacaaa ctagattagc tggtatgata catgcagttg tcttactgct
     3361 ctccatgctt gtttttgcgc cagtgatgtc acagtttcca atgccagcac ttgcaggtgt
     3421 tttgattgtg acggcttggc gtatgaatga atgggaaacg atcaaggagc tatttactaa
     3481 taaatattgg tcagcagttc tattgtttat ccttacgatg atttgtacag ttatctttga
     3541 tttaagtatt gctatcgtga tcggggtgat cggcggctgt gtattttttg ttgtcaaaag
     3601 cgctgctatc acgatttcat tagaaacgat cgattggcaa agaatggggc tgccagaaac
     3661 ggaaaagctg aataactgga cagtagtgta tattagtggt ccactgtttt ttatgtcttc
     3721 agaaaaactc aaaaataaat tggaagaact aaatcatcac gatggtgtca ttttctccat
     3781 gcgaggcgta ccaagtattg atttgacggc acgtgcagtt tttgatgaat ttcaagaaaa
     3841 agcagagcaa agaggacaaa cgattatcta tacttccttg cagccagaag tagaaaaaca
     3901 actttctcac ttgtgggaac atacattcac gcatcaacat caaacagttg ctcatgcgtt
     3961 gacagcttta catgcgaaat atactgcaat tagccattaa aacaatgaaa aagaacagac
     4021 aagactgtaa actgaagatt ttatggtctt gtctgttctt tttaatattg ctgtaaaagt
     4081 gaagctagta cttgccagtc ttgatggata acaggtacaa gggagcgatt gtagaaaata
     4141 gctgctggat gaaaaagtgg aagaattcga tagttttttt ctgaccattc gtaggcatcc
     4201 ttttgttctg ttaattgtaa gacaggccct gtatagagtt gaccatgatt tttggtaacc
     4261 gtatattctt tgccaagtaa acgttgaaga ccaatgtttc caagtgtcgc aattaatttt
     4321 ggctggacct tcatcagttc gtaatccaat attggtgcat gcgcaaatac ttcggaacga
     4381 gtaggtgtcc gatttggata aacagtttct gactgttgtg tccgtttatt gatccgatga
     4441 gtcacgcgat acgggcggct ccttacagca ctggtgatat acacctcttc tcgtgttaag
     4501 ccagttgaag aaagtgcctg catcaattct tttccagctt gaccgctaaa aggaacatgc
     4561 gtatcaatct ctgttttccc tggggcttct cccacgagca tcagtttagg atgaagaggt
     4621 ccttgcccag cgataaatcc ttctacagga cggccgttca ttcttaaaga agcttcttgt
     4681 atcagttctt ttgggtattc catttatgct cctccttttt cttttattat aagaataaaa
     4741 gaaacacaat gcgactattt tatttggtag aactgtgagg atagaaaagc agaagtattg
     4801 cttgaatttt tgttttactt tttgatttta aatttagttg actaacggtt gctgttctgg
     4861 taagctagta ctgttgtaat tgtggactcc acagctacaa ccgctcagaa caagtaataa
     4921 gcacagcata tgctgtcact tcggatggcg agtctaagta tatcagaagg aggtgcttta
     4981 tagcatgtac gcaattatta aaactggtgg taaacaagta aaagttgaag tgggacaagc
     5041 aatctatgtt gaaaaacttg acgttgaagc aggagaaaaa gttgtttttg acgaagttat
     5101 cttagtaggc ggagaatcta caaaagtagg cgctccaact gttgcaggtg caactgttga
     5161 aggtactgtt gaaaaacacg gcaaacaaaa gaaagtcgtt actttcaaat acaaacctaa
     5221 aaaacattca caccgtaaac aaggtcatcg tcaaccatat acaaaagtgg ttatcgacgc
     5281 gatcaacgct taatagcgtt tgagaaagaa ggcctatata tgatcaaagg aacatttaag
     5341 cgaaatgacg caggtcagat cgtttcattc actttgaccg ggcatgctga tgctggtcct
     5401 tatggaagtg atatcgtttg tgcgggtgtt tctgcgttag cgatcagcac tgtcaacggg
     5461 attgcctcat tagccggttt tgagccgatt gttgaaatga atgaagaaga aggcggttat
     5521 ctttataccg aagtcacttc aggaatgaca caagaacaaa acaatattgc tgagattcta
     5581 ttagaaaatc ttttattagg attacaatcg atagaagctg aaaactcaga atatatccaa
     5641 attaaaacaa ttaatgataa ataggaggtg cagaccatgt tgttatctat gaatctacaa
     5701 ttatttgccc acaaaaaagg tggcggttct acatctaacg gccgtgactc agaatcaaaa
     5761 cgtctaggtg ctaaacgtgc tgatggacaa acagttacag gtggatcaat tctttaccgt
     5821 caacgcggta caaaaatcta tccaggtgta aacgtgggta tcggtggaga cgacacttta
     5881 tttgcaaaag ttgatggcgt agtacgtttc gaacgtaaag gccgtaacaa aaaacaagtg
     5941 tctgtttatc cagtagctca agaagcttaa ttgaatctta tgattaaaga ggttgtgaca
     6001 agacttttgt cacagccttt tttgtttata aaaataaaag ttgtagtgga ggctacgaag
     6061 tttactttgt ctttttacac ttaatatttt tttgccaatt tggaatcagg atgttttgat
     6121 aactatcgtt ttcaattgat ggaagctata ttgtttgcta tcagtgaaat aattatatgg
     6181 taaacagtgt tctttttctt gtttccatta taaaaatcgt atcgggattt ttcgttcttt
     6241 taaattgaac atttctatct atccgcgtgt tatcaacaaa acaaaatcag gtaaatagtt
     6301 gacgaaacag aaataaatac atagtattat gttttgaagc ctaagtacaa tagtctatag
     6361 aaaaggagcg ataccattgg caaaacgcat tgaccgaatt tatatgtatg tcaaagaaaa
     6421 aaccgctcat ttaacaaagg cagaatatga tcaaggagta acaacacagg aaattgctga
     6481 agtgttaggg attcagcgaa caaatagcag taaagatctg aatcagctag tgcgcgaagg
     6541 aaaactgata aagacagacg gacgaccagt acgttacata tatcaaacac tcgttacgca
     6601 cgtaaagcca gttacaaaac atgtagtcag ttacaaagaa acgccggtct ctgaagaaaa
     6661 aaatacactc caaatagata ctaaggatat ctttgcaaaa atcattggag ctaacggcag
     6721 catgaaaaat tcagtggaac aggcaaaagc tgcgattttg tatccgccaa gaggattaaa
     6781 ttgtttgatt acaggaccta ccggatcagg aaagacttat tttgcacacg cgatgtatca
     6841 ttttgcaaaa gcgcatcatg taatagatga ggaaacggaa ctgattgttt tcaattgtgc
     6901 tgattatgcc aataaccctg agcttttgat gagtcattta tttgggtacg caaaaggtgc
     6961 ttttacaggc gcagatgaag aaaaaatggg gattatcgat caagcggatg gcggtatgct
     7021 gtttttggat gagattcacc ggttgccgcc tgaaggtcaa gaaatgatct tttactttat
     7081 ggatcatgga acttacagtc gtcttgggga aacaacgaaa tcccatgaag caaatgtacg
     7141 gatcgtaggt gcgaccacag aagacccagg ttcttctcta ttagaaactt ttgttcggcg
     7201 tatcccaatc aatatcaaac ttccggcttt tgaaaaacgt cctgcaaatg agaaagtcga
     7261 tttagtaaaa atcatgattg cccacgaagc aaaccgcacg cagcgaaaga tttctttgac
     7321 agaagatgta gcaaaagcat tgatcggcag tgtgacctat ggaaatatag gacaattgaa
     7381 gtcaaatatc cagttagtat gtgcacgagg atttctaaat catatgcaat cacccgaaat
     7441 ctcgatcaca atcgatgatt tgacagaagg gattcgtagc ggattgattc aattagcaag
     7501 caaccgcagt gcaatggcag agctttctaa aatattggag ccaaagataa ctgtagcacc
     7561 aaatgatacg atcatgaaaa tccaatcgga ctcctatgag ttaccttata atctatatga
     7621 tatcatcgga gataaagcag ctttactgaa gtcggatggt ttggatcaag aagcaatcaa
     7681 tcatttcatt tctacagata tcaacatcca tctgaagtct ttctataaag accatggttt
     7741 ttcttttaat gcagacagca aattagcaga atttgtagat ccgaaaatca tagaagtgac
     7801 caatcagatt tatgtaatgg tcaaaagatc tttaccatat gagtttcagc aaaactttat
     7861 ttatgctatg agcttgcata tcagttcttt tttgaaaaaa atcaacttag gagaagaacg
     7921 gcatacgaat gataacatcc gtgagatggc ttttgatttt ccagatgaat atgctgttgc
     7981 gaaagaagtg cgtagttata tcgaaacgta ttttcaagtg gagattccag aaagtgaaga
     8041 ctattacttg accgttctac tcgtctcgtt acgggcaaat caagcaagcg gcagaatcgg
     8101 tgtagtcgtt gcagctcacg gaaacagcac agcaagcagt atggtccaag ttgtccaaca
     8161 gttgttagat gcagagaacg tacgagcagt agacatgcct ttggatatgg atccgaaaac
     8221 agcattggac cgaattgaac gcaatgtaca agaagtagat gaaggaagcg gggtcatact
     8281 cttagtagat atggggtccc ttgcgtcgtt taattcgcaa attcaaagag acactggaat
     8341 tccagtacgt actgttgata tggtaacaac ttctctagtt ttggaaactg tacgaaaggt
     8401 ctcagtatta gggacagatc tagatatgtt gcatgaatca ttgaaaaatt ttcgaggtta
     8461 cgcagaaata tcttctgtag aatctgttca ggaagcaaaa cctattcata agaaaaaagc
     8521 tgttttggct atctgcgcat ctggcgaagg tacagcacaa agaatcaaag aattgatcga
     8581 acgagcggta aacaagcgtc aagaaacaga attagaagtt ctagctttgt cgattgtgga
     8641 agtgaaagaa gaactgccag ttatccaaaa agaatatcag atcatagcta ctactgggat
     8701 tactgatttg aatatccaag ccccatttat tcctttagaa cgttttattg atcaaaatat
     8761 cgaagtcatt ttggatcagt tgctgatgga atcagaattg gaggaaactg aattcatctc
     8821 cctagatgaa gagtcagcta aaaatacgtg tgttgagttt atctctgata acttcatctt
     8881 tattaatggt agtaagttaa tcgatccaat gtggcaattt tctacacaaa tctctcagac
     8941 gacgggaatc ggcgatgaag aatatggatt caaaatcaac ctagtgatgc acacagcagg
     9001 aatgatcgaa cgtattattc ggaatgaacc attgactgtg gaagaaaacg aattgacaaa
     9061 tacaacgaat gatcctcttt atagccaatt ggcagcctca gttgttctgt tggaagatca
     9121 gataaaagta aaagtgccga tagaagaaat gtattatctg ctacgtctag tccataatca
     9181 gttagataaa aaagaataca ctgtgccatg aatacacaaa aacgatacac ttttatagtg
     9241 tatcgttttt gtgtattggt taagaatcct ttaaattcaa ttagtgtatc gtaaaaaagt
     9301 tggcacgctt tttgcttata gtagtgtgtg ctaggaggtg gttgttcaca cagaaatgat
     9361 aggggtttct gtgaagtagt gaggaagaag gagttttgca gatggatatt cgattggcac
     9421 gtatagatga tcgtttaatc cacgggcaag tcgcaacagt ttggtcgaag caaacaggtg
     9481 ttgaacgtat cattgtgatc agcgatgtag tcgctcaaga taaattgaga aagtttctac
     9541 taaaagaagc tgcaccgccg gggatcacag caaatgtaat aaccgtgcag aaaatgattc
     9601 aaatctatca tagtggatta ttatcacgag caaaagtgat gcttttattc accaatcccc
     9661 aagatgttga agcggttgtc cgctgcggtg tacagttgaa gtcgttgaat atcggcggta
     9721 tgagttttac tgaaggcaaa tcaatgatta ccaattttgt ttcagtaaat caacaagata
     9781 ttgattcctt tcgttacttg aacagtcaag aagtggagtt agagattcga aaagtacctg
     9841 ctgacaggaa aatccttttg atggaactac tagcgaaaat caaaaaggtg tagcaagaat
     9901 ggttgttgga aaaggtcaaa taattctgtt gtaatggtta gcaattatta atatttttga
     9961 atttgttaca acaaaagtaa ataggaggta taaatatggt agggattatc ctagcaagtc
    10021 atggacaatt tgctgaagga atcttacaat ccggttcaat gatctttggc gaacaagaaa
    10081 acgtcaaagc cgtgattttg aaaccaagtg aaggtccaga tgacttgaga gccaaattgg
    10141 aagaagcggt tgcttctttt gataatcaag acgaagtgtt attcttagtt gatttatggg
    10201 gcggaacacc gttcaatcaa tcaaacacat tattcgaaga gcacaaagat aaatgggcaa
    10261 tcgtcagcgg tttgaattta ccaatgttga ttgaagccta cgcatcacgc ttttcaatgg
    10321 aatctgctca tgaaattgca gcacacatca ttgaaacagc aaaagacggt gtaaaagtaa
    10381 aaccggaaga attagaaccg gcagaagcac cgaaagcagc agttgaagac gcacaaccta
    10441 aaggagcact tccagaagga actgtggtcg gagacggaaa aatcaaatat gtattagcac
    10501 gtgttgactc acgtctgtta catggacaag ttgcgacagc ttggacaaaa gcagtgcaac
    10561 caaaccgtat tatcgttgtt tcagatgcag tatcaaagga tgatctgcgt aagagactaa
    10621 tcgaacaagc tgctcctcca ggtgtaaaag caaatgttat tcctattagc aaaatgatcg
    10681 aagtagcaaa agaccctcgt tttggaaata ccaaagcatt gcttttattt gaaaatcctg
    10741 aagacgtatt gacagctgtt gaaggtggcg tagacatcaa agaattaaat gttgggtcaa
    10801 tggcgcattc ggtcggtaaa gtcgttgtaa gtaaagtatt gtctatggga caagaagacg
    10861 ttgaagcgtt tgagaagctt gaacaaaaag gtgtgaaatt cgatgtacgt aaagtaccta
    10921 atgattcacg cgataacatg gatgatattt tgaaaaaagc aaaagctgaa ttagcaaaag
    10981 cgtaataaat aatattaaaa tttataggag gcttatcatg tctattattt caataatttt
    11041 agtcgtatta gttgcctttc tagctggtat ggaaggtatt cttgatgaat ttcaatttca
    11101 tcaaccacta gtggcatgta cattgatcgg tttagttacc ggtaacctcg aagctggtat
    11161 cgtacttggc ggtacgcttc agatgatcgc tttaggttgg gcaaatatcg gtgccgctgt
    11221 agcaccagat gctgcattag catcagtagc atcagcaatt attttagttt taggtggaca
    11281 aggtgttaaa ggtgttcctt ctgcgatcgc gattgccgtt cctttggctg ttgcagggtt
    11341 gttcttaaca atgatcgtac gtacaatcgc tgttccaatc gttcatttga tggatgcggc
    11401 tgctgaagaa ggaaacatcc gtaaggttga aatgtggcac atcattgctg tatgtttaca
    11461 aggggttcgt atcgcggtcc cagcagcagc gttgctattt atcccagcac aaactgtgca
    11521 atcattcctt gaatcaatgc cagcatggtt aacagatggt atggctatcg gtgggggaat
    11581 ggtcgtagct gtaggttacg ctttggtaat caacatgatg gctacaaaag aagtatggcc
    11641 attcttcgtt attggtttcg ttgtagctgc aatttctcaa ttaacattga ttgctctagg
    11701 tgctttaggt gttgcattag ctcttattta cttgaacctt tctaaaatgg gtggttcatc
    11761 aaataatgga ggcggaagca actctggtga ccctttaggc gacattttga atgactatta
    11821 atcttgaagg aggaaaataa aatggcagaa gaaaaaatca aattatcaaa aaaagatcgt
    11881 ttagctgttg cgtggcgctc taccttcatt caaggttcat ggaactacga acgtatgcaa
    11941 aacggtggct gggcattttc tatgattcca gcaatcaaaa aattatacaa aacaaaagaa
    12001 gaacgttctg cagcattaaa acgtcacttg gaattcttta atacacaccc atacattgct
    12061 tctccaattt taggggttac attggctctg gaagaagaac gtgcgaatgg cgcgcctgtt
    12121 gatgatgtag cgattcaagg ggttaaagta ggtatgatgg gtcctttagc tggtgttggt
    12181 gacccagtgt tctggtttac agtacgtcca atgctaggtg cactaggtgc ttcattagct
    12241 atgggaggaa atatccttgg accaatcatc ttcttcttag gttggaacat tattcgttgg
    12301 gcattcatgt ggtatacaca agaatttggc tacaaagctg gttctaaaat tactgatgac
    12361 ctttctggcg gattgttaca agacgtaaca aaaggtgctt caattttagg gatgttcgta
    12421 ttagctgccc ttgtacaaag atgggtatca atcaaattct taccagttgt atcaactgta
    12481 aaattagata aaggtgctta catcgaatgg gataaattgc cttcaggtgg tgaaggaatc
    12541 aagagtgcat ttgaacaagt taataatggc ttagcccttt ctcctgaaaa ggtaacaaca
    12601 ttacaagaca acttagacca attgattcct ggtttagctg cattaggatt aacattgtta
    12661 tgtatgtggt tgcttaagaa aaaggtttct ccaatcgtta tcatccttgg tttattcgta
    12721 gtcggtgttg ttggacacgt catcggactt ttataatcca taaaaatata gctcgggcgt
    12781 tgtcccgagc tttttttata tagtatactg ttcataaaca aatatctgga gggagaaaat
    12841 ggttcaatca atcaatacaa aagtagactt ggtaattgat gctacttcgt ttacgggtct
    12901 gacagattac gggcaaatca tgataggtaa taatggtttt gagttttacc atgcgcgaga
    12961 tagacgcaaa tatatccaaa ttccatggga agaagtggat tatgtactag catcagtcat
    13021 gctaaaggga aaatggattc ctcgatatgc cattcaaacg aaaaaaaatg gtacatacac
    13081 attttcttcc aaagaaccta aaaaagtgct tcgtgcgatc agagaatatg tagatgaaga
    13141 tagaatggta caatcattga gtttctttga tgtagtgaaa cgtggtattc gtagtatgtt
    13201 taaacgcaag taaaaaataa agaaaacttc taagaggagg ttttctttat ttttttactt
    13261 tgcagaagaa aatatgaaat agcaaaacca attatttgtc ccctttaaat cccatatgct
    13321 aaaattgatt agcaaagaag gaggttatat tatgagttgg ttatggacat tgattgttgg
    13381 agccgtgatc ggagcaattg caggtgcgat caccagtaaa ggaaattcga tgggctgtgt
    13441 aacgaatatc attgctggac tagtcggttc aagtattgga caagcgattt tcggcgaatg
    13501 gggaccaaaa gctgcaggta tggcacttat tccatctatt ttaggcgcag tgattttggt
    13561 agcagttgtc tcatttttct ttggaaaacg atcataagtt tttacaaaat agtaaactaa
    13621 aaggagttgc agcgagactg tgactccttt ttggctttat ttatttaaaa taaaaagaag
    13681 ttttccggaa atttttattt aactgtcgtg tacgaagaaa agtttgctat aatggaaaaa
    13741 agcgtgcaaa gaaagaggga gtttcattat gatgctacgt gtagaaaaat tgcgcaaaaa
    13801 aatgcaagaa gaaaatttgg attcattttt ggttaccagt ccgtacaatc ttcgttactt
    13861 aacgaacttt acaggtacga caggattagc tgttattact ttggaaaaag cattttttat
    13921 tactgatttt cgttataccg agcaggcggc agcgcaggct caagggtttg aaattattaa
    13981 aaatgtcgga cctatttttg atgaggtagc aaacttagta cgcaaagaag aactgcactc
    14041 attagctttt gaggaaacaa cagtctcatt tttagaatat tcggttttag aagaaatcat
    14101 cgatgcggaa ttagtacctg tttcacagat gatcgaagaa ctcagagaag tgaaagatga
    14161 agaagaaatc gctattatcg aaaaagcatg tcatattgcg gatatggcat atgatcacat
    14221 cctgaaaatg atccaaccgg gcatgactga gattgaagtc gcaaatcaac tagactttta
    14281 tatgcgttct cttggcgctt caggtgtttc ttttgatacg atcgttgcta gcggattgcg
    14341 ttcggctatg ccgcatggtg tagcaagcaa aaaaatcatc gaacaaggtg acttgatcac
    14401 attggacttt ggttgctatt acgaagggta cgtttccgat atgacacgta cattcgctat
    14461 tggtgatcct ggggaaaaat taaaagaaat ttatcaaata gtcttagatg ctcaattagc
    14521 agttattgat gctgcaaaac caggaatgac tggtgtccaa ttagatgcag ttgctagaga
    14581 ttatatttca aaacatggtt acggggaagc atttggacat tctacaggac atgggatcgg
    14641 tttagagatc cacgaaggac caaacgtttc ttctcgtgca gaaaagcaat ttgtaccagg
    14701 aaatgtgatc actgatgaac cagggatcta cttaccagga atcggtggag tacgtattga
    14761 ggatgacttg ttgatcacag aagatggaaa tcgtgtgttg actcgttcac caaaagaatt
    14821 gatcatctta tagtttcatc aatagaagaa gtaagcgtaa aaatcagtgt tcacagactt
    14881 tgttatagaa aatcactcga tttaatgata cactatagaa gaacttttaa gctgtaagag
    14941 ataataaagt tgggtgtttt ctccaattca tagcagtttg cagctgatcg gcggcagttt
    15001 tcttaccacg tgatcactat gccgcatcat agagaattcg gatgtatctc gtgcttaggc
    15061 aaagggagga ataaataaat ggcagatgaa aaaaatttga ttttaaacgc aaaccaagat
    15121 ttaggagaga tcgtgatcgc tcctgaagtc atcgaagtaa ttatcgggat tgcagcttct
    15181 aaagtagaag gcgtatacgg aatgcgcgga acttttgcca gcaatgtcac tgaattatta
    15241 ggacgtgcag ctcacggaaa aggtgtttac ttagcaaacg aggaagatgg cttgaaagta
    15301 gatctttact gttatctaga atatggtgtt tcagttccta aagtagcaat ggaaatgcag
    15361 gaacgggtca gccagcaagt ccttttcatg acggatatcg atttatctga agtcaatatc
    15421 catgtagtag ctgttgttcc tgaaaaatta gaacaaccaa caatcgaaga actttttgaa
    15481 gacgaagagg aagagaatga ataaagaatt atcaagacac gagattcggg aaatggcatt
    15541 gcaggcttta tttccattag acttcaatgc agacctaaca aaagaagatg cgattttcaa
    15601 cgcaatcgaa ttagaccacc gcgacatgat caacgaagat gaatcagagt ttgttcctgt
    15661 ttatcttgat acgctagttg gcggtgtctg tgcaaaaaaa gatgaattgg ataaagtgat
    15721 tgaaaaacat ttaaaaaaca attggcacat caatcggatc tcaaaaatgg atttggtgat
    15781 cttgcgtatc gcgatttttg aaatgactta tgtgacagat gtaccagcgg ctgttgcttt
    15841 aaatgaagca atcgagttgg caaaaacatt tagtgatgac cgttcacgta aattcgtcaa
    15901 cggtgtttta tccaatgtat tgaaagaatt agaagctggg gcgtaagtcc tagctttttt
    15961 ctatgaatca tcataaacct gttataaatc gggaaaattc tatggtagaa tgaaaacaca
    16021 aaaaatatct gggagtggtt agatggcaga attgattaac ggaaaagaat tagctgaaaa
    16081 aatgcaggca gagattgctg aaaaaatcca aaaattgaaa gataatggta tccatcccgg
    16141 attagtcgtt ttattggtag gggaaaatcc agccagccaa atctatgtaa gaaataaaga
    16201 acgtgtagca aaagaaatcg gaatccattc attggtagag cgttatcctg agacgatttc
    16261 tgaagacgaa ctacttgcag aaattgaaaa atacaatcaa gatcctagtt ttcatggtat
    16321 attggtccaa ttaccattgc caaagcatat agatgaagaa aagatcctgt tagctatccg
    16381 ccctgaaaaa gacgtagacg gttttcatcc gatgaattta ggcagactcc ttgcgggtaa
    16441 accggacaag attccttgta ctccatacgg catcatgaaa atgtttgaag cttattctat
    16501 cgatccggcg ggtaaacgag cagtagttat cggacgaagc aatatcgtcg gtaaaccgat
    16561 ggctcagcta ctcttgatgg cagatgcaac tgttactgtt gctcattcta aaaccgaaaa
    16621 tctggctgaa ctggcacaag aagcagatat tttagtcgta gcaataggac gtggacattt
    16681 tgtcacaaaa gaattcgtaa aaccaggtgc tgtagtgata gatgtaggga tgaatcgtga
    16741 tgctaacggt aagctgatcg gtgatgtgaa atttgatgaa gtggagccta ttgcaggctg
    16801 gatcactcct gtgccaaagg gtgtagggcc aatgactatc acgatgctga tgtatcaaac
    16861 cgtaaaatct gccgaagctt ttggagcagg tgaatagatg gcacaagaat atttaactgt
    16921 cactacatta acgaagtatt tgaaaagaaa atttgatgcc gatccttatt tagaacgcgt
    16981 atatttaaca ggcgaaatat cgaatttccg tttacgtgcc aatgcccatc aatatttcag
    17041 cttaaaagat gaccatgcaa aaatatctgc tattatgttc aaaggagcat tccaaaaatt
    17101 acgattccag ccaaaagaag gaatgaaagt ccttgtcgtt gggcgtattt cattatatga
    17161 agcgggaggt tcttatcaaa tctatgtaga gcacatggag cctgatggaa taggtgcttt
    17221 atatcaagaa ttggaagaac gaaaagaaaa gctgatgaag gaaggccttt ttcaagggcc
    17281 taaaaaaatg ctgccacgtt tcccaaagcg aatcgcggtc cttaccagtc caagcggagc
    17341 ggttatccgc gatatcatca cgacggtgaa aagaagatat ccaattgtcc aattggtttt
    17401 gttcccaaca gttgtacaag gaaaccaagc agcggacaat gttgtcagga atatccagag
    17461 agtagaagag atgggcaatt tcgatacaat gatcatcggt cgtgggggtg gttcgattga
    17521 ggatttatgg ccgtttaatg aagagcgggt tgctcgggcg atttatcaag ctaatacgcc
    17581 ggtgatttca tctgtaggac atgaaacaga taccacgatc gctgatttag tagcagatgt
    17641 tcgggctgcc actccaacag cagctgcaga attagctgtt cctgttttgt cagaagagtt
    17701 gatgcgcatt caagaacggc aagctagatt gcagcaggcg tttgtacgcc agatccagcg
    17761 caaacaagaa cggttcgagc gtgctcgacg ttcctatgta tttcggcagc ctgaaagatt
    17821 gtatgaaggt cagaccatca aattagacca gttgaaacag cgattatatc aagctacaca
    17881 gcaaatttat catgcgaaag aaaaacaaac gatcgcatta agccaccaat tggaacaagt
    17941 ggctccgctt tatcgagtta aagcagctcg ccaagaaact gcttatctag aaaaacgctt
    18001 agaagagaaa atccaacaat atatgaaaca acagcagcag cgttttgctc aagctgttca
    18061 atctcttgat ttgttgagtc cattgaaaat catgggaaga ggctacagct atacgacgtt
    18121 aaatgatcaa gtagtaaaaa gtgtcaccga gattcatcaa ggggatttgc tgacgatcca
    18181 ttatcaagat ggaatcgtta aaggacaagt acaagagata gacaaaggag aataaaaata
    18241 tggaaaatcc aacttttgaa gagtcactgc aagaattaga aaaaattgtc atgcagttag
    18301 aacaaggaga cgttccatta gaatcagctc tagattcgtt taaacgagga atggaattaa
    18361 gcaaacattg ccaagataca ttagctaaag cagaagagac cttgacgaaa atgatgacag
    18421 aatcaaatga agaagttgat tttgacggaa acgaggaaag ctgagatgag attaactgac
    18481 ttttcagcta ttcatctacc tgctgtagaa aaagaaatct tgtctttttt agatgagcat
    18541 acaacggata gaggactcta tgatgcgatg agttattcag tgaaagcagg cgggaaaaga
    18601 atacgtccct tattactttt aacggccgtt gcttcctttg atgagcctat tgatgttccc
    18661 gtctatcaag tagcagctgc tttagaaatg gtgcatacgt attccttgat ccacgatgat
    18721 ttgcctgcga tggacaatga tgatcttcgt agaggaaaac ctaccaatca taaagtattc
    18781 ggcgaagcat tagctatatt ggccggagat ggtttgctta caggagcatt ccagctaatc
    18841 agtatggcac acttaggtaa ttctcctaag cttctgctgc ttcagcaatt agctgtttgt
    18901 gcgggatcac aaggtatggt tgctgggcaa gctgcagata tcgagggcga atcgaaaaag
    18961 ctttctttag aagaattagc atttattcat gaaagaaaga cagggcattt gattcgttat
    19021 gccttgctgg ctggtggcat attagcgaag caacctgaag aaatcttatt gctacttcaa
    19081 cgattagccg aacatttagg tttagctttt cagataagag atgatctact cgatgtgatt
    19141 ggtacaacga aaacattagg gaaaacagct ggtaaagatg aacgtatgga aaaaaatact
    19201 tacccgcgtt tattaggcct agaaaagaca cgtgaggcgt tggagattga gctgttatcc
    19261 gccaacaaga tcatagacaa attagaagag gacgtttttt cttttgatgg cgggctgatg
    19321 cgccagatga tcaagcaatt tgatgtggag aaatgaggga aagaatggaa aaagaacgcg
    19381 tagatgtatt agcggtcaaa caaggattat ttgaaacaag agaacaagcc aaacgttcag
    19441 tgatggctgg tttgatttac aacgaaaaaa acgagcggtt tgataaaccg ggagaaaaaa
    19501 ttccagtgag tagtgaatta agagtcaaag gtaaaaaact tccttatgtt tctcgagggg
    19561 gattaaaatt agaaaaagca ctcaaagcat ttgatctatc tgttgaagga aaaacattgt
    19621 tagatattgg tgcatccact ggcggattta ctgatgcagc tttgcaaaat ggcgcaaaaa
    19681 tgagttatgc tttagacgtt ggctacaatc agctagcttg gaaaataaga caagatccta
    19741 gagtcgtcgt aatggaaaga gtgaattttc gttatgcaaa acccgaagac tttaccttag
    19801 gaattccaga agttgctgtt atcgatgttt cttttatttc actaaaactg atgctgcctc
    19861 cattacatgc tattttaaaa gaagagggag aagtgattgc tttaatcaaa ccccaattcg
    19921 aagcaggcag agaagctgta gggaaaaacg gaattgttcg tgaccctcag acccatcaaa
    19981 aagttttaga agacattttg tcatttgcgg cacaaggtgg atatgatgtg ctggaattaa
    20041 gttattctcc gatcacgggg ggagaaggaa atatcgagtt cttggctcac ttgaggaaag
    20101 tacccgaaag cggaacaatc aattcagcta ttaatatggc agaagtggtt tcaaatgcac
    20161 acgaacagtt tgaccataaa taaattgtaa ctgtgaaaat caagtgagaa gtatgcggat
    20221 tcttctttat tataccaagg aaataagcta tcattgatta agaagaatat gctaaggagc
    20281 gaagacgtaa tgagaaaaaa agatcggcat cgtttgatta ctcgattgtt gagtgagcaa
    20341 gatatccgaa agcaggaaga atttgttgaa atcctgaaaa gcaaaggaat atctgttact
    20401 caagctacga tttccagaga tataaaggaa ctgaaactga tcaaggtacc ggcttcagat
    20461 ggcggctacc gttatagcat accagctgaa acaaacgaag atgtaaatac taaattggaa
    20521 aaactattaa aagacgcttt cgtggcagtt gaccaaatgg aaaaatttgt tattttgaaa
    20581 acattgccgg gaaatgcttc ggcagcagca aatttgattg ataaacgtta caagaaagaa
    20641 ttattttcga ttatcaatga tgacgataat gttttgatga ttacacgaac tgaagaccag
    20701 gcagttttat tgaagaaaga cttcctgcat tacctttaag ttgaggagcg aatgtgatgc
    20761 tacaagaaat cagtattact aactttgcga ttattccgga attgcggctt tcttttcacg
    20821 aaggaatgac cgcgctgacc ggagagactg gtgcgggtaa atccattatt atcgatgctt
    20881 taggtctgtt agcaggagga agaggttcaa gcgattatat acgtcaagga gcagaaaaat
    20941 gtgtgcttga agggttgttt gaactaccaa aacaagaagg attctctgaa ctgatggttg
    21001 aattagggat cgaaacagat gaggacaatc tgattgttcg acgggatatg tccttaactg
    21061 gaaaaaatgt ttgtcgagtg aatggtcata ttatcacatt agctaatctg agaagaatcg
    21121 gcagttattt agtagatatc caaggacaaa acgaacatca ggaactgctc cagcctgaat
    21181 cacatcttgc tttattggat cgttttggag atgtagcttt ccaacagaag aaaaagagtt
    21241 atcagcaaga atatatctct tatcgtgagc tggaaaaaag ggtacgaaaa gtgcagcaaa
    21301 atgaaaaatc ctatgttcag agaatagata tgctccattt ccagcaagaa gaaatagctg
    21361 ctgctgattt gcaagtcgga gaagaagaga aattaaaaga agaaagagaa aaacttagca
    21421 attatcaaaa aattgctgat ggattagctg caggttacgg agcactgacg aataatgaac
    21481 aaaacagtgt agatggtgtt ggcttggccg tttcagaact gcaagggatc gcccatctag
    21541 atgtggagta tgaagcaatt tatgaaaata tccaaagtgc ttactatttg ctgcaagatg
    21601 caatcggcga tatgagtcgt cagattgatt tattggagtt agatgagagt cgtttagaag
    21661 aagttacgca acgtttagaa ttaatccgac agttgaaacg taaatacggc gaatccattg
    21721 agtcaatatt ggcttactat gacgaaatca ccgaagagct agcttcttct gatttttcag
    21781 aaggtcaatt ggacaaaatg aaagaggaac tagagcaaaa agagcttcta cttcagcaac
    21841 aagccgcaga tcttcatgaa gcgcgtaaaa aaatcgcaaa agaattggaa aaatccattc
    21901 tgcatgaatt gaaaagtctg tatatggaaa acactgagtt tgaggtacgt ttcttaaaag
    21961 aagaaaatag acaattgaat catgatggat ttgaccaaat cgaattttac attacgacca
    22021 atccaggaga gccactgaag cctttggtga aagtcgcttc tggtggcgaa ctgtctcgga
    22081 tgttgcttgc tttgaaaact attttttctt ctgagcaagg tgtgacaagt attatttttg
    22141 atgaagtgga tacaggtgtg agcggaagag ttgcacaggc catcgcagat aaaatttctc
    22201 aaatatcgaa atactctcaa gttttgtgca tcactcatct gcctcaagtt gctgcagtcg
    22261 ccgactatca atattatatt gtgaaagcag tgattgatgg acgtacgcaa acttctgttt
    22321 cagagttgaa aacaaaagaa agagaagaag aaattgcacg tatgctggct ggaagtgaga
    22381 ttacaaaact cacactcgaa catgcaaaag aactattgaa actcgcaaaa aggacctgag
    22441 ccacctcgca gtggttcagg tccttttcag cagctgatag ctatatttta tttttacatg
    22501 acactcatta cagcagtcaa tacaacagat ccaatcgtta aaatcagcat tgtccaaatg
    22561 acaaattttg ttactttagc aaaagtactt gtttgttttt tttcacgcat tgttttcaac
    22621 ctcgtcatta attagttgat tcaagtgtac aatctttttt ccatttccac aagagggctt
    22681 ttttataaaa acttcccttt ttttaaataa taggtagtta cgatacaaat aaataatgtt
    22741 aatagaacta gccatataaa ggcatcatcc ctttcagcaa taggtaactt aatgttcatt
    22801 ccatagatac tgccgacgat tgtcggtata gttaaaataa tcgttaaaga agttaaaatt
    22861 ttcataatat tattcagatt attcgatacg attgctgaaa aagtctgatt catttgttct
    22921 actagtttta attgaatgcg agaagtagtc attgcctgct ctgtttccac caatacatca
    22981 cgtaaatgat ttttcaaagc atgattttct tggaaaagtt tattttgcgc tagttctttc
    23041 aatgcatcta aattagcaga agtcgcttct ctgaaataaa cgaggctttt ttggatatcc
    23101 atgatttgat aaagttgttt gttttcagtg gatacttgaa gtttggcttc caaagtatcg
    23161 cattgagatt gaagcgtagc taaataactg ttgtaagaga gtgtgacctg ccaaatgaat
    23221 tgaaagaaga tattgagatt aggcgaaata tcactttttg gaaaggtctg gctaaagact
    23281 ttctttaaaa acagtggttc atgattcgta attgtgataa gcttcttttt gggcgtcaaa
    23341 ataatagaga gcgggtatgt atccacttga aaataaccgc taggacttgt tttagcaaaa
    23401 ggatattgta acaataataa cgctggcttt gtcaactttg attgattgaa ttcttctgta
    23461 cgggaatttt ctgcatcgtc caatatggaa gtgatgtaat ctgacggaat ttcaaattga
    23521 tgtgtcagct gatgaatctc ttcttgatta ggacgttcta cacaatacca gatcgtttgg
    23581 tcagtttcct ttccggtatt acgcagtttc tcattatcta atgtaaaata tttgatcatg
    23641 attttcctcc tgttgcctgt ttcttttatt ataacggata gggaattgga atacatggaa
    23701 tgtgtttgta agatatagaa tataactgca taaatttaaa taaaatgaaa cagttgtgta
    23761 aagtatatac agtatacttg aagcaacgat aaaaaaggag tttacgttca tgggcacatt
    23821 cacaccactt atcttgtttt ggtatattta cccggtaatc gttttgtttg gttgccaatt
    23881 tcttgtaaaa ttattttcgt taaatcgtcg ttttaaaata aaagcccctg atttggcgat
    23941 tccttttttg tggggcggta tgcatgcatt gtctagaaat acagggacaa tttctatctt
    24001 accgtttttc tttatttctg ttttgctaat gggaatttgt attgctgttt tccaagcata
    24061 ttattatgaa gaaattattt atccgcgtta tttcaagatg acttggcgtt tggtttttct
    24121 gttgacaatc gtcttgtacg ctgtcttgat cattgtgaac atactttctt acctatgaaa
    24181 aaaatagaaa agctgtaaaa agtcttttaa aaggcttttt gcagcttgat ttttaaaaaa
    24241 atgtttatga ataaaaaaag ttgttcccgg atttcccaga aaaggtggta gaaagtgggg
    24301 gattgtggta gactaatttt agttagtgga ggaatggggg gctttcaatg ttgatgggtg
    24361 aattccaaca taatattgat gcaaaaggac gtttaatcgt gccctcaaaa cttcgtgaag
    24421 aacttggcga aaagtttgtt ctgacacgcg gattggatgg ctgtcttttc ggctatccga
    24481 tgagcgaatg ggaaaatctg gaagctaaac tgaacgaaat gccgttggct aaaaaagacg
    24541 cacgtacttt tgtgcgattc ttctattcgg ctgccactga atgcgaactt gataaacaag
    24601 gacgaatcaa tatacccagc acgttaagaa attatgcagc tttgacaaaa ggttgcgtag
    24661 tcatcggtgt atctaaccga attgaaattt gggatgagac acgatggcaa gatttttctg
    24721 cagcagcaga agagaacttt gacgaaattg ctgaaagtat gattgatttc ggactataag
    24781 aataggaaga ggctgactaa tgactgaaac atttcaacac tatacagtca tgttgaaaga
    24841 aacggtagat ggattgaaca tcaaaccgga tggcgtttat gtagactgta cactcggcgg
    24901 tgccggacat agtgaatatt tattaagcca actaagttct aaagggcatc tgtatgcgtt
    24961 tgaccaagat caaaaagcaa tcgatcacgc caagctgcgt ttagcttctt atgtcgaaca
    25021 aggtatggtc acatttatca aagcgaactt cagagaatta gaagaacgct tgagtgagca
    25081 tgtagataag gtagacggca ttttgtatga tctaggggtt tcctctcctc agctagatga
    25141 agcagaacgt ggatttagtt atcatcaaga tgcaccgttg gatatgcgca tggatcagtc
    25201 agctccttta tccgcttatc acgtaattaa tgaatattcc taccatgaat tagtaaagat
    25261 tttcttccgc tatggcgagg agaaattttc caaacaaatt gctcgtgaaa tcgaacgagt
    25321 acgaaaaaca aaaccaatcc aaacaactgg tgagcttgtc gaaatcatta aacaagtcat
    25381 cccagctccc gcaagaagaa aaggcgggca tcctgcaaaa agaatttttc aagctgtgcg
    25441 gattgcagta aatgacgaac tcggtgccga agaggcctct ttagaacagg caatccggtt
    25501 attgaaagtc aatggaagaa tcagcgtaat cacattccat tcattggaag acagaattgt
    25561 caaaagtatg tttaaagaat atagtacggt acaagatcta ccaccgggac ttcctgtcat
    25621 acctgacgaa ttccaaccag aactgaaagt cattactcgt aaaccaatcc ttccttcaga
    25681 ggaagagcta acagaaaaca atcgatcacg cagtgcaaag ttacgtattg cagaaaaaat
    25741 aagaatgaaa gaggagtaga atgatggcag aattaaagaa aatgcaagat tacgaatatg
    25801 atttacctga attggtggat cagccggaac aacaaatgcc tgattcttct tcgaatcaag
    25861 aaatcattct tccacaatca ccggcaaaac gattaaagca gatttctgct ttggaaaaaa
    25921 ttgctgtggc aagcgtggcg attgctattg ttgctttatg tgttttaaca gttatgctgc
    25981 gcacaaatat cagcggagct gaaaaagaaa tcacgtcaat acaaacagaa atcaatgata
    26041 aaaagcaaga aaaaacgagt ttagaacaag aaaaaaacga actttctcgt actgaacgga
    26101 ttaaacaaat cgcagaagaa aaaggattgt ctattaatga cgacaattta aggaaagtga
    26161 agtaaatgag tcttaaaaat aaaattcggc ggtttatgga aaagaaaaat ctaaatccga
    26221 tgaacaatcg caaaaaagta ggtatcattt tatttgctac gagtattgga ttgttctttt
    26281 tatttgccgt ccgtttctcg tatatcgtta ttggaggtca tgttgctggt acctcattag
    26341 ctgaaaaaac aaaacagttg taccaaggaa gtgaagtagt aaaagcaaaa agaggaacga
    26401 tttatgatcg taacggtgtg gcgctcgcag aagatgcctc ctcttattca attaaagcga
    26461 tactctcaaa aacatatacc tctggggata aaaaactgta tgttgaagaa aagaattttg
    26521 ataaaatagc agaaatcctg cataagaatc tttctataga caaaaaagat gcactgaata
    26581 ttttagagga cggcgcaaaa aaagagctgt atcaagttga atttggtagc tatgggaaaa
    26641 atatctccca agaaaccaag caaaacatcg aagcggacat gaaaaaagaa ggtgtcgctg
    26701 gtctttattt tgtcgaccat caggctcgga tgtatccaaa tggcgtcttt tcttctcatt
    26761 ttattggata cgcagttcca gacaaagatg agaatggctt agttggtaaa ctaggtttgg
    26821 agtctgctta caatgatatc ttgagcggta aagatggtaa gattatttat caaaaagata
    26881 attttcaaaa tcctctgcca ggtacagtgg cagaagaaga aaaagctgtc gacggacaag
    26941 atatctacac gactttagac agcagactac aaagttattt agaaacactg atggatcaag
    27001 taaatgaaga atatcagcca gaagaattga cagcagtcct gatgaaagca aaaaccggag
    27061 aaatcttggc aatgggacaa cgacctactt tcaatcctga aacaatggaa ggattgactg
    27121 gaaaagatgc tatctggcgt aatttcttgg tacaagatag ttatgaacca ggatcaacca
    27181 tgaaagtttt cactactgca gctgctatcg aagaaggaga attcaacgag aatgaaacct
    27241 tccaatctgg aaaaatccaa gtagaagatg ctacgatcaa tgaccatgac tttggtgaaa
    27301 aaggtgtgct gaccatgcgt caagctcttt catggtcaag taacgtcggg atggtcatac
    27361 tggaacagcg attaggcgga cgatggtata actatttaca aaaactggga tttggacaaa
    27421 gtactcattc tggattagat gatgaagtaa acggtgcttt acctacatta aatattgtcg
    27481 accgagcaat gagtgcttat ggacaagcgg taggtgtgac gaatttccaa atgatgaaag
    27541 ctttcacttc tattgcgaat aacggtacaa tgattcaacc tcgatatatc agcaaagtgg
    27601 tggatcccca aactggagaa gagcgaacaa ctcaaacaga agttctaggg caaccttttt
    27661 caaaagaaac aacagaaaaa gtccgtgaat atatgagaga tgttgtcgaa agcgaaaact
    27721 acggtagtgc ttatggtgta tatagtgtac ctggatacaa tgtatcggca aaaaacggaa
    27781 cagcccaaat cgcttctgat acagggggat atcaaacagg agatacagcc tacctgtatt
    27841 cgattgtgga gatggttcct tctgaagatc cagactatgt cttgtatcta acaatgaaac
    27901 accctaagac atatgatcga atggcattgg ctaaaatcgc aaatccattg atgaaacggg
    27961 caatggattt taaagaaact gaagaagatt cagatacaga aacaaaaaca gaaaaagtat
    28021 ccgtagccga ttatcgtaat cttgaagcgg acgttgcagc agctgatgct caaaaaagtg
    28081 gactgcaacc tgtagtgatc ggtaatggta aaaaagtaca aaaacaatct actgccaacg
    28141 gtgatcagtt gatctctgga gaaaaactga tcctatatac tggtggtgat aagctgatgc
    28201 ctgacgtaac aggatggtca aaagcagata tcatgaagct ggggaaaatc ctcggtattg
    28261 aagttagttt tgatggagat ggttattgtg tcaaacaaga acttgctcca tatgaaaaaa
    28321 tcactgaaga caaacttagt tttactttag aagaataaga agagaaatag gagagaaaag
    28381 agcatggaat ggacacaagc attgattccc attgtcagca gttgtgcaat gacaattgcc
    28441 gcaatgccgc tatttattgg ttattttcaa atgaaaaagc aaggtcaggc gattcgtgag
    28501 gagggaccaa agtggcacaa tagcaaagcc ggaactccta caatgggcgg cttagtgttt
    28561 ctgatcggct ctattttgac aggaatttgg gttggagctt ggcaaaaaca gctaactcct
    28621 actcttttca tcttgctttt tgtattagcg ttatacggag taatcggctt tcttgatgat
    28681 tttataaaaa tattcaagaa aagaaacatg ggactgaact cgaagcagaa attgattgga
    28741 cagattctag ggggaatcat cttttatctt gtttaccgtt ctgaaggtta tccaggtgta
    28801 ttgaatttct tcggactaga tctaccttta ggaatcattt atggtatttt cgctctcttc
    28861 tggcttgttg gattttcaaa tgcagtaaat ctgacagatg gcatcgatgg attagttgct
    28921 ggcttaggaa gtatctcttt tgcagcttac ggtctaattg cttggcatca gcatcagtat
    28981 gatgtattaa tcatttgctt aagtgtttta ggaggtttac tgggtttctt cgtctacaac
    29041 agaaaacctg ccaagatttt tatgggagat gtcggttcat tagcgttggg cggactttta
    29101 gcggcaattt ctataatgct aaaccaagaa tggacattgc ttttgattgg tttgatctat
    29161 gttatggaaa cagcaagtgt gatgcttcaa gttacttcct ttaagcttac aggaaaacga
    29221 atttttaaaa tgtctccaat tcatcatcac tttgaaatgt gcggatggtc ggagtggaag
    29281 attgatacag ttttttggtt gatcagcatt gtgacttcgt tgatcacatt atggatcgtt
    29341 tggtaggaga tgacgggaaa tgaaaaaaat atcaacatat gaaaataaga aagtgcttgt
    29401 cttaggactc gcaaaaagcg gagtaagtgc ggccaaatta ttacatgaat tgggcgcact
    29461 tgtcaccgtt aatgatggaa aaccttttga cgaaaatccg gaagcacaag agctgctttc
    29521 tttagggata aaagtaataa caggtagtca tccaatcgaa ttgttggatg aagaattttc
    29581 attgatggtc aaaaatccag ggattcccta cagtcatcct ttagtagcaa aagcccaaga
    29641 aatgggtatt ccggtaatta cggaagttga gctagcttac gaagtagcgg aatgcccaat
    29701 tattgggatt acaggaacga acggaaaaac aacgacaaca acgatgacag gactactact
    29761 gaatgcagga gcagatcaag gaattgcacg tttagcgggt aatattgggt atccagcaag
    29821 tggtgtagcg caagaagcaa aatcagaaga taaaattgtg atggaattgt ctagcttcca
    29881 actcatggga atcacagatt tccgccctca tatagcggtg attaccaata tctatgaagc
    29941 acatattgat tatcatggta caagaaaaga atatgtcaaa gctaaatgga accttcaaaa
    30001 aaacatgaca gaaaaagatt atctgatcct taactggaat cagtcagaac tacaagaatt
    30061 agcgcaaaga acaaaagcac gcgtactgcc tttctcgaca aaagaagtgt tggaagacgg
    30121 tgtgtatgct gacgattact caatatacta taaaaaagaa aaaataatgg aaatatctga
    30181 acttggcgta ccaggtaagc ataatgtaga aaatgcacta gctgctattt ctgtagcaaa
    30241 attgtatggt atatcaaatg aagctatacg agaaacgttg cattttttcc atggcgtacc
    30301 acatcgtacg caatatgtag gagaaatcca aggcagaaaa ttttataatg attcaaaagc
    30361 aaccaatatt ttagcgacta aaatggctct aagtggattt gaaacgtcta aggtcgtgtt
    30421 attggctggc ggattagaca gaggaaatac atttgatgaa ttaattcctt cattaaaagg
    30481 aatcaaagca atggtcgtat ttggccaaac aaaagaaaag ttgatggatg ctggaaaaaa
    30541 agcaggcatc gagacaatag taacagccga ttctgtagaa caagcagttc ctttagcatt
    30601 agaaaacagt acagatggtg atgtagtttt attatcacca gcgaatgcca gctgggatca
    30661 atacccaaat tttgaaacta gaggaaacag attcatggaa gctgtgaacc gattaaaata
    30721 gaaaaagtag aagcgagcga taaaaaatga aaattttggt tacaggcgga ggaacagggg
    30781 gacatattta tccagctctt gcctttgtca attatgtaaa gactcaagaa ccgaatgctg
    30841 aattcatgta tgtgggagca aaacgaggtc tagaaaacaa aatcgtccct gatacaggaa
    30901 tgcctttcca taccttggag attcaaggat ttaaacgaaa aatttccatg cataacatca
    30961 agacggtccg attgtttctt aagagtatcc gtcaagcaaa aaaaatcctc agtgattttc
    31021 aaccagatat cgttatcggt actggaggat atgtttccgg agcggtagtg tacgctgcag
    31081 ccaaaatggg tattccaaca gttatccatg aacaaaacag tgtaccaggt gttaccaata
    31141 aatttttaag ccgatatgtg gatcggatcg ctctttcatt taaagatgcg gcttcctttt
    31201 ttcctgaaaa caaagcagtt cttgtaggta atcctcgagc acaagaagta gcagatacta
    31261 aaaaatcaga tattttgaaa acatttgatt tggatccaga aaagaaaaca gtcttgattt
    31321 ttggcggtag tcaaggagca cttaaaatca atcaagcagt atcagttttt ttaagtgaat
    31381 atattccttc ttcttaccaa gttttgtatg cttcaggaga tagatattat gaagagatcc
    31441 taaataaaat aaatcctgaa atacaaaata ttagtgtcca gccttatatc aaaaatatgg
    31501 cagaggtcat ggcttccagt gatctgctgg tggggcgtgc tggtgcaact tcgatcgcag
    31561 aattcacagc tctggggtta ccggcagtgt tggttcccag cccatatgtt acgaatgatc
    31621 atcagactaa aaatgcaatg agtcttgttc acgcaggagc agcaaaaatg attgcagata
    31681 atgaactaac aggtgaatca ctaagtcaga cagtcaacga aatcatgggt gatgaagaat
    31741 tgcaaaagca aatgtgccga gcttctaaag aacaaggaat ccctgatgct tcaaaacgtc
    31801 tttatgactt agtaaaacaa ataatcaaaa aataaaggcg gtggtcttag tgagtaagaa
    31861 aaaagaacca aaaaaattgt ctcatccgtc ttctgatgaa aacaatttga ctccttggca
    31921 aaaggctaac cgaaaatatc tggcagaaca agagatgaaa aaccaagagc caaaaaaaga
    31981 agacataaca ttagatacac ccctttcaga ttctgaagaa gaaaaaacgg ttcaagagga
    32041 acagcaagaa gaaagccagt ccgagaaaaa aatcgaattt tttgaagaga tcaagcaaaa
    32101 gaaaaacggt ggaccatata acggttcttt tttgaaccgg ctgcccaatt taaaaagtca
    32161 acggcacaaa gtactatttc gtcggttagc tttgatcatc actgtattgg gtataccgct
    32221 gatttttttg atctattatg tttctcctta tagcaaatta caagcagttg cagtatcagg
    32281 caataagaca gtcaacagcc aagaaatcat ctctgataca aaattgtcat taggagaaaa
    32341 tgtttgggga cagtattttc atcgatctac ttatatcgat cgccttaaaa aagcacagcc
    32401 aagaatcgaa acagcaaata tacatttcaa agggatgaat gaattcgatt tggatgtaac
    32461 agaatataaa gagattgctt tgatcgcaaa aaacaatcaa tactacccag tgattgaaaa
    32521 tggaacagta ttagatgaaa aagtagcaaa tcctacaaaa aatctcccta tcttggaaga
    32581 gttcaaagac tctgcaaaaa tcaaagaatt aacaaagcaa tacaatcagt tatcatcaga
    32641 attacaaaaa gcaatttctg aaatcaagta cacgccaaga gcaagcaata aaaatctgat
    32701 ccaattgaat atgaatgacg gcaatcaagt tattgtaaat atcaataatc ttgcgaacca
    32761 aatgaaatat tattcgcaag tagccaaaga tatggatgaa aaaggtgtga tcgacatgga
    32821 agttggtatc ttctcgcatc cttacggtag cactcaagaa acggaagaat cgggccaatc
    32881 ggaagaaaca actgaaagtg aagaaaatgc ggatcaaaca aacgaatcaa gtgaagaggc
    32941 agaaacgcaa aaagcacaaa cacctggatc gtctagcaca aacggatcat ctgattcaaa
    33001 tgattcaagt gaaacaagtc aaatagaaga taatccaagt acaactccgt caagtttaaa
    33061 tgaaaattga taaaacaact ttaaaaagta agaatgtact ttctaaaaac cagtaattta
    33121 tggtagaatt ggaagcagtg aatatatcta ttaataagta tattttaaaa cggacgctag
    33181 ttgttcgctt gtatatggaa tagtaagtag gagggaatcc cattcatggc aaaaacagga
    33241 atgtatgtag gccttgatat tggaacgaca tctgttaaag ttgtcgtggc tgaatatatc
    33301 gacagccaaa tgaatattat tggagtagga aacgcaaaat cagaagggat taaccgaggc
    33361 attatcgttg atatcgataa aacggtccaa gcgatacaac gagcagtacg acaagcagaa
    33421 gaaaaagcag gtatccagat caaaggcgta agtgtcggtt tgccagcaaa catgcttgaa
    33481 gtagaaaatt gccagggaat gattgcagtt aacggagatt caaaggaaat caccgatgaa
    33541 gatgtcagaa atgtggcttc agctgccctt gttcgttcaa tacctcctga acgtcaaatc
    33601 gtgtcaatat tgccacaaga ttttactgtc gatgggttcg agggaatcaa agatcctcgt
    33661 ggaatgatcg gcgtaagatt agaaatgtac ggtctgttgt ttacaggacc taaaacgatc
    33721 atccataaca tacgtaaatg cgtggaaaat gccggattaa tcgtcaacga aatggtgatt
    33781 actcctttag cgctgactga atcaattctt tctgacggag aaaaagattt tggtacgatc
    33841 gtcattgata tgggtggcgg ccaaacaaca acggctgtta tgcatgataa gcaattgaag
    33901 tttaccaatc ttgaccaaga aggtggcgaa tttgtcacta aagatatctc tattgtatta
    33961 aatacgtcat ttaacaatgc agaagcgttg aaaataaact acggggatgc atacccagaa
    34021 cggacatcac cagatgaaga atttccagta gatgtgattg gtcagtcaga accagtgaaa
    34081 gtcgatgaac gctacttgtc agaaattatt tcagctcgaa tggaacagat tttcaacaaa
    34141 gcaaaagatg cattggacca aatcgaagca ttagagttgc caggtggcgt cgtattgaca
    34201 ggcggagctg ctagtcttcc tggtgttgtg gacttggcac aagaaatctt cggcgtaaat
    34261 gtaaaattgt atgttccaaa tcacatgggg ctgagaaacc cggtatttac aaatgtaata
    34321 agtatcgtgg attattcagc aaacttgagt gaagtgtatc aattggcaaa aattgctgtt
    34381 acgggtgaaa cctcagcagc tcgtcaaatg gtagttgaac aagaaacaac aaacacatat
    34441 gagagctatg aagcacctga agaaacaatc tacgatgagc cggaaccaaa agagtccgga
    34501 gaaaatgtaa aaaataaaat caagggtttc tttacaaata tttttgatta attcatcctg
    34561 ggaggaataa gatatggaat tctcaattga taataatatc aatgacggcg cagtaatcaa
    34621 agtcatcgga gtcggtggtg gcggtggaaa tgctgtaaac cgaatgattg aagaaaacgt
    34681 taaaggtgtt gaattcatta cagccaacac agacgtgcaa gcattaaaaa attcaaaagc
    34741 tgaaacagtt atccaattag gccccaaata tactcgtggt ttaggtgctg gttctcagcc
    34801 agaagttgga caaaaagcgg cagaagaaag tgaacaatcc ttacgcgaag ctttagacgg
    34861 tgcagatatg attttcatca ctgcaggaat gggtggagga accggtacag gtgctgcacc
    34921 aatcgttgca ggtatcgcga aagaattggg cgcattgact gttggtgtcg tgacacgtcc
    34981 attcactttt gaaggaccga aacgtggccg ttttgctgca gaaggtatcg ctcgtttgaa
    35041 agaaaatgtg gatacattat taattatctc aaataaccgt ttattagaag ttgtagataa
    35101 aaagacaccg atgcttgaag ctttccgtga agcagataat gttttacgac aaggtgtaca
    35161 aggtatctct gatttgatca cagcgccagg ttacgttaac cttgactttg ctgacgtgaa
    35221 aacagtgatg gaaaaccaag gtacagcatt gatggggatc ggtgtggcta gtggagaaga
    35281 tcgcgtagta gaagcaacga aaaaagcaat ctcctctcca ttgcttgaaa catctattga
    35341 tggagctgaa caagtacttc ttaacatcac aggcggtttg gatatgacat tgttcgaagc
    35401 acaagatgct tcagatatcg tagcaaatgc agcaactggc gatgtaaata tcattctagg
    35461 tacatctatc aatgaagaaa tgggcgatga aatccgtgtg acggtcatcg caacaggtat
    35521 cgatgaatca aaaaaggaac gcaagtctag ccgaccagct agacaagcac aaatgcaatc
    35581 acctgctcaa aagactgtat tagatatgga tcaagctaaa ccaacttctt cagaagaaga
    35641 aaacagtttt ggcgattggg atatcagacg tgaacaaaat gttcgtccta gagttgatga
    35701 ttccaatttt gacaatatcg aaaaaaaaga atttgataca ttcaaccgcg aagaaacaaa
    35761 atctcatggc gatgatgaat taaatacgcc accgtttttc cgtcgtaaaa aataaaggag
    35821 aggaagagca catgattgct gacaacttgc agaaaatcaa gcaagaaatt caggattcgt
    35881 gtgctcttgt tcatcgtgat ccgaaagaag ttacattagt agctgtaaca aaatctgttg
    35941 aatccgctca agctgaagaa ttggttagag ctggcgttat gaattgtgca gaaaaccgag
    36001 tagataaatt attagaaaag aaacaagatt tatttgattt tcctgaaata aagtggcatt
    36061 taattggtaa tttacagcgc agaaaggtaa aattgattgt aaatgaaatt gattactttc
    36121 atgcgttgga cagtttaaga ttagcagaag aaatccagaa gcggttagag aaagaattat
    36181 cctgttttat tgaagtaaat gtttctggtg aggaatcaaa acatggaatt tcaccagatg
    36241 agcttttacc gtttgtggaa tctttagctg cctgcacaaa aatcaaggtt gttgggttga
    36301 tgactatggc gcctaaagaa gcttctgatg agcaaatcca taaagtgttt ggtacgctga
    36361 aagaattgcg tgatcttgtt caagcaaaag gttatgccca tgcaccatgt agtgaattaa
    36421 gtatggggat gagtcaagac tttcaaattg cgattgaaga aggtgcaaca tttatccgtg
    36481 taggaacagc gctattcaaa gacgaataaa ggaggaacaa aaatgccgct tttaaacaga
    36541 ggagcaattg ctaatttttt cggattagct gatgaggaag agtacgaata ccaagattat
    36601 cctgaaacaa caaaaaaggc tgtacagcca actaaaaaaa atacaacaca gaatcaatca
    36661 actcattctg tatctgctgc gaatactcat gaaaaacaaa aaacggcgac ttcacgtcct
    36721 gtaacgcatg aaagtattca gccggctgaa aagaaaaaag taattgaact acatcaatca
    36781 cctacaaaaa ctgtagcgaa agaaagaaca gcttcaagaa cctctacaca acctaaagca
    36841 aatcttgctg gaaaaatcac tgtaatggaa ccaagagctt attctgaagc tatggcgatt
    36901 gctaaacgaa tcattgctgg agaagcaacc ttagtgaatt ttcatttagt agaagaaaaa
    36961 caagcgagaa gaatcgttga ttttctaaca ggaacagttt atgcactaga tggagatatc
    37021 aaacgtgttg gagatgagat ttttctttgt acaccgactg ggatggagat tgacagttca
    37081 accgctcaat cttttgcaga tgcgaatttg tttgatctgt aagaggagga actacgattt
    37141 atactattgc actattactt catttacttc aacgggcagc ctatttctat agcattatct
    37201 tgatggtata tgcattgctc tcttggtttc caggcgggta tcaatcaggg ctaggacgat
    37261 tattagctaa gatctgcgaa ccgtatatca gtttgttcga tcgtctgcct ttgaggattg
    37321 gacccttgga tttcacaatt ttaggggcaa tcctgatctt gaacttagcc gtacaaggtt
    37381 tagcacagat cgttatatgg ataactgtcc atttagttta ttgattgaag caacaaaatc
    37441 tttattctca gaatagatag gaggggaaaa ttttggatgc aaatgtatac cagcactttc
    37501 gggcagatga acgtacattt atcgattcgg taggcgattg gattgaacag gttcaaggac
    37561 aatatgcacc ctatctgacc gaatttcttg acccaagaca atcctatatt ttagaaacac
    37621 tgattcgaca aagcagtgat ttgcgtttca tgttttatgg cggatatgaa caggcagaaa
    37681 gaaaaagatg tttgattttc cccgattatt acgaacctgt agaggaagat tttgaaacag
    37741 cattgtatga aatccattat cctagcaaat ttgccagcct aagtcatggg aaaatccttg
    37801 gaactttagt gggaacgggg atcaaacgct cttactttgg cgatatcatc tcggacggtg
    37861 atcgctggca agtatttatt gcaaatgagg tggatcattt tgttgctgca caagtaacaa
    37921 agattggaaa ggttgctgta cgcttggaac caatcaaata cacagaaatg attatgccga
    37981 aagatagctg gacacaagaa agaggaacag ttagttccat gcgactagac agtgtgatct
    38041 ctgagattta taatatttcc agacagcggt ccaagcagct gatcgaagct ggtaaagtaa
    38101 aagtgaactg gacagaaaat acaagacctg attttgtact tgaactatta gatattattt
    38161 cagtcagagg ttatggcaga gtccagatcc aagaacttga ggggaagacg aaaaaagaaa
    38221 agtacagggt actgttcggt gtattacgta aataaaataa aaaggtggtt tactcatggc
    38281 tttaactcca ttagatatcc aaaataagac attcccgaca aaaatgcggg gatataatca
    38341 agacgaagta gatgatttct tagatttagt tgttcgtgac tatgaggaat tgactcaaag
    38401 aaatcgagaa ttagaaaaag cagtcaaaca ttctgaagaa aaacttgagt acttcaatga
    38461 attaaaagat gctttgaacc aatcaatcat cgtagctcaa gatacggctg ataaagtaaa
    38521 aacaagtgca agcaaggaat ccgaagtgat cgttacttct gcacaaaaca aagcagatga
    38581 gttagttgcg aacgctgaaa aacgtgcaca tcaattaaca actgatgcag aagaaaaagc
    38641 aagaaaaatc ttgacagatg caacagaaaa agcaagacag cttgcgacag aaactgaaga
    38701 tcttaagaaa aaaacacgag tattccatca acgtatcagc ttgatgcttg agtctcaatt
    38761 agaacaagtg aaaagtccgg aatgggatga aattttacaa ccattctcca gctacgtgac
    38821 tgacagccat gaagtgatca aagaagtttt agcaaaacag cttgacaatg aaaatgatac
    38881 tgatgtaaac tcagacacag gagtcataga agcacctatg acggcatttg atacacaggc
    38941 tattgatatc tcgatcgtgc ctggtgaaaa tgaaaacgag tagaacagaa aagcactttg
    39001 ttattcttaa agcgagccga tgagagtgga agttcggtaa gacactgcat ggtgaaagat
    39061 cctctacttg agacctgctt ttccgaaatt agagtaagaa gcagcggctg acctcgttat
    39121 tggtcacaga gagtttgcac tagatagatg caactaaatt tgggtggtac cacggcatgt
    39181 tcgtcccttg cggctgaaca tgcttttttg tgtccggaaa acaaataaag gagtgtatgg
    39241 ttgaatgaaa atgaaagaaa ccttgcaatt aggaaaaaca aaattcccta tgcgtggtaa
    39301 tttgccaaac cgagaaggcg agtggcaaaa agaatgggaa gaaaatcgaa tctaccaaaa
    39361 aagacaagag ttgaacgaag gaaaacctag ctttgttctt catgatggac ctccatatgc
    39421 caatggtaat atccatttag gacattcatt gaataaaatc agtaaagaca ttatcattcg
    39481 ttcaaaatca atgtctggct atcgtgcacc atatgttcca ggatgggata cacatggatt
    39541 gccgattgaa caagtattgg ctaataaagg cgtgaaacgt aaagaaatgt ccatggcaga
    39601 atacttggaa aaatgtcgtg aatatgcact ttcccaagta gataagcaac gagcagattt
    39661 caaacgccta ggagttgcag gagattggga acatccttat gttacattag atccttctta
    39721 tgaagctgca caagtacgcg tatttggtaa aatggctgaa aaaggctata tttacaaagg
    39781 attgaaacca atttactggt ctccgtcaag tgagtcttct ttagcggaag ctgaaattga
    39841 atataaagat gtaaaatctc catctatttt tgtagctttc aatgtcaaag acggcaaaga
    39901 tattcttgat gaagatacag cttttgtcat ttggacgaca acaccatgga cattgccagc
    39961 aaaccaaggt attgctgtaa atccaaaatt tacgtatgta ttggtggaag ccgatggccg
    40021 taagtttgtc gtagcgaaag atttgctaga aacagtccaa tcagaaatcg gttgggaaaa
    40081 tgtaacagtt ctaaaagaat ttgctggaca agaaatggaa tatatgactg caagtcatcc
    40141 attctatgaa cgtgaatcac ttgtgatttt aggcgatcat gttactttag acgctggtac
    40201 tggattagtc catactgctc caggacatgg ggaagatgac tatatcgctg gtagcaaata
    40261 taaactatct gtagtgtcac ctgtagactc aaaaggattg tttacagaag aagcacctgg
    40321 atttgaaggt atcttttatg acaaagcaaa tcctatgatc actgatctat taaaagaaaa
    40381 aggagctttg ctgaagctag atttctttac tcatagttat cctcacgatt ggcggacgaa
    40441 aaagcctgtg atctatcggg caactccaca atggtttgca tctatcgata aattccgtca
    40501 gaatattttg gatgaagtag aaaaagtaga gtgggttatc ccatggggta aaacacgttt
    40561 gtataatatg atccgtgacc gcggcgattg ggtaatttcc cgtcagcgtg catggggagt
    40621 accacttccg attttctatg ctgaaaatgg agaagcaatc atcacaccag aaacaatcga
    40681 acatgtggca aaattatttg ctgaacatgg atcaattatc tggtttgaaa aagaagcgaa
    40741 agaacttctt cctgaaggat ttacccaccc aggttctcct aatggcgaat ttacaaaaga
    40801 aaaagatatc atggatgtct ggtttgattc tggttcttct catgaagctg ttttacgtca
    40861 gcgaccagaa ttatcattcc cagcagatat gtatttagaa ggatcagacc aatatcgtgg
    40921 ctggttcaac tcaagtatca cgactagtgt ggctatcaat ggtgtagcac catacaaatc
    40981 agttatttct caaggatttg ctttagatgg tgaaggccgt aagatgagta aatctttagg
    41041 aaacatcatt gcaccagaaa aagtgatcaa acaatttggt gcagatatcc ttcgcttatg
    41101 ggtatctagt gtagattatg aagcagatgt tcgtgtttct atggatatct taagtcaagt
    41161 ggcagaagta tatcgtaaaa tcagaaatac gatgcgtttc ttattagcga atacagaaga
    41221 tttcgatcct aaaaaagata ctgtttcgta caatgattta cgttctgtag acaaatatat
    41281 gaccgttcga ttgaaccaag taatcaaaga aatccgagaa gaagggtacg acaaatataa
    41341 cttcatgcat atttaccgta cagttatgaa cttcttgacg gttgatctat cgtcattcta
    41401 cctggatttt gctaaagatg tagtttatat tgaagcagaa gatgattatc aacgtcgttg
    41461 catgcaaact gttttctatc aaacagctgt agctttgaca aaattattga ctcctatcat
    41521 tccgcataca gcagaagaaa tctggtcatt cctgaaagaa gaagaggagt acgttcagtt
    41581 aagcgagttt cctggttatg aagagtttgc aaaccaagaa gaattgatgg atacctggac
    41641 tgctttcatg gacttccgtg ataatgtctt aaaagcattg gaagaagcaa gaaacagcaa
    41701 attgattggt aaatctttgg aagcaaaact aactgtttat ccaaaacaac aagttcgtga
    41761 aatgttaaaa gctttggatg cagatattgc acaattattg atcgtttcac cagactactt
    41821 tgaagttatg gcagcagatg aacaagtgcc agataacgct atggtatttg atgatgttgc
    41881 tattacagtg gaaaaagcag acggggaaac ttgcgatcgc tgtcgccaag ttcgtaaaga
    41941 tgtaggagta gatgaaaaac ttcctcatct atgcggtcgt tgtgcaaaaa tcgttgaaga
    42001 cttctatcct gaagctgtag ctgaaggatt cgaagaaaag taaaagggaa aagggggtgt
    42061 gacatgttct ttgtcacacc cccttttgtt atcaatcgtt taattttcca cgttcacgat
    42121 accagttatc tggttgccag atccattcga atccgtcttt ttcaagtagt tcgaaagctg
    42181 ctttaggtcc cattgatcca gctttgtagt tgggaaaatc cggttgtgtt tggtcccaag
    42241 cttttcgaat gacatccacg atatgccaag attgagcgac ttcttcccaa tgagagaagt
    42301 tcgttccatc accattcaac gcatctaata gtaatttttc gtaagcttct gggctatttt
    42361 caaccatttc tgcactattt ctaaattcca atttgattgg ttccgtttca aatccttgcc
    42421 ctacttcttt cccattcaag gataaagaaa atccttcagt tggctgaata tagatcgtta
    42481 gaacattagg tggaagtgtc gtatcgtcac atggttcatc gacagatgtt ttgaatacat
    42541 taacaggaac ttgtttgaat acgatgttga tccgagtccc tttttcagtc aaacgtttgc
    42601 ctgtacgtac atagaaagga acacctgacc aacggaagtt atcgatagtg aatttgcctg
    42661 cgacgaatgt ttcagtctct gattgagcat ccactttgtc ttcttcgcga tagcccttga
    42721 attgtacacc atccaattca ccttgagcat attgcccgcg aacgaagttt tctaacactt
    42781 cttcttcgtt ataaatgcgg atagctttca atgctttgat cttttctgta cggatttctt
    42841 tttcggaaaa tgctactggc ggttccattg caagtaatgc tacaacctgt aaaatatgat
    42901 tttgcaccat gtctttaagt gcgccactat gatcgtagta gcccccgcga tcttctacac
    42961 cgaggttttc gccaaaagta atttggatat tgtcgatata gcgattgttc cattgagcct
    43021 caaaaatatt attggcaaaa cggatagctg agatgttttg gatcatttct tttcctaaat
    43081 aatgatcaat cctgaaaata tcttgttctg ggaatacttc tctgatttgc tggttcaatt
    43141 caaaagcaga ctggtaatca gaaccgaacg gtttttctat gatcaaacga ttgaagccat
    43201 tttttgtcat aatattttgt gatttcaaat gagaaacgat cgttccaaaa aattgaggtg
    43261 ccatagccaa ataatagaca cggttaccgt ttaattgata gtgtccatct aatcggtcag
    43321 acaattcttt taatgtctga taatgcgttg aatcatttac atcatgggat tgatagtaaa
    43381 aatggcttgc aaaggtagtt gcttcttcat ctgaaggatt caatgcacgg attgtttctt
    43441 tgacaacttc acggtagtgc tcatcgctcc agggacggcg agcggttccg attacagcaa
    43501 aatgctcgcc taaatttcct tttctgtaaa ggcggaacaa agacgggtac aatttacgct
    43561 gggctaggtc acctgtaccg ccgaatatcg taaacaatac atttttttca ttagacatgt
    43621 ggatacactc ctttatattt tatcgacaaa aatcgtgctg gccgccttaa agctgacggg
    43681 gattttcttt ctatcatttt ggatagtgat cggtccttca taagctgcga tgtcaacgat
    43741 ctcatattct tcgttgatat tcaggtcaat agtgactaag taatccaaca attctttttc
    43801 atcaagcact cgtgcgatac gcacttttgt accgacagga taggactcca atgtttgtcg
    43861 gcgttcttca tggacaactt cctctttttt aggaatcgat cctccatgag gacaatgttc
    43921 aggatgattc aaatagtttt ctaaatgatc tgcaagatgt tccgaagtca catgttccaa
    43981 tacttcagca tcatcatgga cttcattcca gctatagtct aaatgttcaa ctaaaaaaac
    44041 ttcccataag cgatgtttgc gaatcagact gctagctttt tgcagtccgc ttgcagtcaa
    44101 ttgtacacct tgataagggg aatgttctac aagctcttct ttcacaagtt tagaaatcat
    44161 ttcactgaca gatgcagctg agacatctag actagatacg atttgtttat tgttgacttt
    44221 cgttgtatct ccacctagtt ctaaaatgat tttcaaataa tcttctcgat ttggtgtcat
    44281 attcgatcat cctttcatgg taaaaaacca tcattagtaa gtgtaacaaa aaaaacgtta
    44341 attgactatt tttctaaata aaaaacaaag gatttttaga cgtttttaca acaaaaaacg
    44401 aaagatgata gagaagactc attctttcgt ttataaagga tatatatata cattgggagg
    44461 gatctatttt tcagataaca acttatatga agtgtctgca gattcgtcat aaagagtttg
    44521 ttcgggataa gaaaagataa gataaaaacc atactgatca cgtacgacta aacgatattc
    44581 atctatttct accacagatg tgccaagaga ctgaccgttg atcaaaaacg tgtaatcaga
    44641 tgtaatctgt aattgttgtt tttgctggct atcactaaag aaccatgtac cttgatactt
    44701 tgagagtcct tctgactttt ccgcttgttt tttctttttc aagtaaataa aacttgagag
    44761 aacggtaatg agtgaaccaa gaaaatagat catttttttt atcaccaaat cactccttta
    44821 tgagaaaata atcgcataga catattcttt cttctttatt tcattgtacc gaataaaagc
    44881 taaaatttct ctaagacttt cgactggttt ttttactgtt tttctacaaa ttatgatagg
    44941 atacatagta ggaagaaagg tgacataatt tgaagtatca gcaagtggaa atagcttttt
    45001 ttattgaccg cccgaatcgg tttatagcac attgtatgaa aaaagacgga gaaataatta
    45061 ttgcgcatgt caaaaataca ggtagaggaa aagaggtcct gataccaggc gctgaagtgg
    45121 ctattgtatt tgctcctgga cctaaacgga aaaccgccta tgatctgatt gctgtaaaaa
    45181 agaagggtga ctggtttaat atcgatagtc aattgcctaa tcggctggca attgatggta
    45241 ttttagacgg cacgatcctt ttaccaggat taactggtcc atttacggta tacaagcgtg
    45301 aagtaactta tcttcactcc aaatttgata tttatttaga gacggtggtc ggacaaaaag
    45361 catttgttga agtcaaaggt atgacacttg aaaataaagc gattggtgct tttcctgatg
    45421 cgcccacact cagaggattg aaacatatag gagaattaac gtatgccgca caagatggtt
    45481 atgccgctta tgtcttgttt attgctcagt tcgaacatct tcatctggca acgatccatg
    45541 aagaaatgca accagcacta gctgatatgg ttcgacatgc gcagcaaagc ggagttcaaa
    45601 tcctcgccta taattgtcaa gtatcggcag atgaggtaac tgtcaagcag gccattccat
    45661 ttgatgtaga tatccctttt gaagatccta tacaatagaa agaaggtaaa ataatgatca
    45721 acttaggtat tatcggaaca aattggatta ctcatcaatt tgtccaagca gctttaagca
    45781 caaaaaaata tgaattgaca gcggtatatt ctagacattt ggaaaaagca caggaatttg
    45841 gttctcatta tgaaggggat atcgaattcg caacagattt gaagactttt ttcaatatta
    45901 ctcatatgga caccatttat attgcttctc cgaatagtct tcactttagt caagctaagc
    45961 aagcaatttt ggcaggaaaa aatgtgatag ttgaaaagcc agctttttcg acgccaaaag
    46021 aaatggatga aatcatccat ttggcaaatg aacacaatgt gtattttttt gaagcagcaa
    46081 gaaatatcca tgaatcaggt tttaaaaaga ttgccgatta cttaccatta aaagacgaga
    46141 taatcggtgc aaatttcagc tatatgaaat attcttcgcg ctatgaccaa gtattagatg
    46201 gagaagaacc gaatatcttc tcgactcatt tctcaggtgg tgcattgatg gatttaggtg
    46261 tttaccttgt atatgcagct gttgcttggt ttggaatgcc aaaagaagtc cattatttcc
    46321 caagaaagat ttctactggt gtagatggtc ttggatgggg gatcttacgt tatgagaatt
    46381 ttgatgtatc gatccagcca ggtaaaatcg gtgattctta tttaccgtca gagatttatt
    46441 ttgactcagg aacgctagtg atgaatggag tcaatgcaat tgaacaagca caatttcatg
    46501 atcgcgcgca taaagaaatc attgatttgg cggtaacagc tgcagaaaat ccaatggcag
    46561 atgaagcaga ggattttgcc aatgtcatgg ctcatccgaa agatccagct tggggattgt
    46621 tgtatgaaga gtggatcgag ctagctagaa atgtgaacca agtgatttat gatttaagaa
    46681 aaaatggcgg catcaaattc gatgcagata atgaggaaga tttttaatga acgaatttgt
    46741 acaagtattt cccgaaaatt ggcagaaaaa atatgaggat aaagggttta tctcaccttc
    46801 tcttattcaa cgagcagttt ttcagccact aagtaataaa caaagtatag tagcggtttc
    46861 tcctacaggt tcaggtaaaa cactggctta tctttggcct ctactactaa acgtggaacc
    46921 aggtgaagca agtgcgttgg tcatttttgc ttcttctcaa gaactagcta ttcaagtagc
    46981 agatgttgca cgtgaatggg gaaaagacaa agagttgaaa gtccaatctt tggtgggcgg
    47041 agccaacgtc aaacgtcaga ttgagggttt gaaggaaaaa ccagaaatct tgattggtac
    47101 accaggaaga atattggaat tgatgaaagc aaaaaaaata aaagcacatc aagtgaaaac
    47161 aatggtattt gatgaagcag accagctatt tgacgctggg aacagccaaa tcattgatca
    47221 aattcttcat caagctccaa cagagtatca gctagctttt ttttcagcga cagcagatcg
    47281 ttcccttgaa agcattgaaa aaatcactgg gaaaacgttt gagacaattg acgtgacagc
    47341 agaggacgat tctcgaaaag gactgagaca ttacttttta cgtgtaccga tacgaaagaa
    47401 agatgactac ttgagacgtc tcacgcatat agaagatttt catggtctga ttttctttaa
    47461 tcaactgact gaattaggcg taatggaaga aaaattgctg tatagaggtg taccggtagg
    47521 aagtctggcc tctgatcaga acaagctact ccgaaaagca gcgctagaac aattcaaaaa
    47581 gaaaatggtc agagcacttt tgaccacaga tgtggcggct agaggtttag atattacagg
    47641 tcttccttat gtagtgaatg cagaagttcc gttaagtgaa gaagcttatt tgcatcgttc
    47701 gggaagaact ggtcgaatgg gtaatgaagg aatagtaatt acactcgtac aagataataa
    47761 tctaagagat ttaaaacggc ttttacgtcc atcaaatata acacttgaag agattttttt
    47821 atacggaggt aagctgcaaa ctgagcagcc aaccaaagaa gatgcagctc ctgcagtaaa
    47881 taaaaagtat gcgaaaactt tttctggaaa ggagcagaac ccagaatata acaaagaaaa
    47941 aataagaaaa aaagttaaaa ataaatcaaa aaaagagaga aataaaggag caaggcgcaa
    48001 ataagcgcct ttttatgcta tgattatgaa aacgggaaca aaattggttg ccagaggagg
    48061 ggttatgtga aagaacgtca agaagagatc ttgcagctat tgacagaaaa ccaacaagga
    48121 ttgacagcaa gtgatgtagc tgagcgctta actatcgatc gaagcaatgc aagccgatat
    48181 ttaagtgaac tatacaaggc ccatcatatt gtaaaaaccg ctggccgacc agtcgtttac
    48241 tctttgccaa cggaaaagtc aaaatctgat gaagtgcatg tcgactcttc tacgcaagtg
    48301 acttttgaaa cactcgttgg agaaaatgat tctttaaaag tcagcataca gcaggcaaaa
    48361 gctgcgattc tttatccacc gcgggggttg catacgatta tttttggaga aactggtaca
    48421 gggaagtcga tgtttgctga atgtatgtat cattttgcaa tcgattcaga gatgctttct
    48481 gcagatgcgc catttgtttc tttcaattgt gcggattatg ctcaaaatcc gcaactgctc
    48541 tttggacaca tctttgggat caaaaaaggg gcttacacag gagcagctca agatagtccc
    48601 ggtctaatag ccaaagcaga cggcggtata ttgtttttag atgagatcca ccgtttaccg
    48661 ccggaagggc aggaaatgct gtttactttc attgataaag gtatttaccg tccgcttgga
    48721 gaaagtgcac aagtacatga agcatctgtt cagatcattg gggcgacgac tgaatcttca
    48781 gaaagtttct tatctacgtt caatcgacgg attcctatgg caatcacctt gccgaatctt
    48841 gcttcacgtt cactggatga gcgttatgaa atcatctctc tttttatcaa acaagaagcg
    48901 aatcgtttga atcaacgtat cgatatcgaa aaagaagcga ttcttgcctt catgctttat
    48961 gatgcggaag gaaatatcgg tcaagtgaaa cgagacttga aactagtctg tgcaaaatct
    49021 tttttacatt accgtactca tcatgagaaa aagctaatca ttcgaaaaga agaactttcc
    49081 cttcaagtac aaaaaggatt actgaaaatc aaggaaatac cggaacgtct cgaccgattc
    49141 atggacagca aaagtcagta tttgacattt gaaccaggat ttgctgatgt tgtctggtca
    49201 caagatccag aacgaaacat gcaggtctat aacgatattg aggaaaaagt cacttctctt
    49261 tccgaaaccg gtgtggagaa cattgatcta gagaccctca tttcaaaaga tgtggatgct
    49321 tatttccaga catatgtcaa agaattgact aaaagttcga ttcccaaaga tcttttgcca
    49381 gatgaaatct ggcggttaac caatcaattg tatgatgtgg ctgaaaaacg gttagaccgt
    49441 atttataatg aaaaagctcg ttttgctttt gctttgcatc tgcaaagtac attggatcgt
    49501 gtgagagaag gtcatatgat cgtccaccca gatttgaata acgtacggaa aaattttaag
    49561 agggaattcc aggtagcaat cgatctttca acgatcattg aagaagaaga acaagttgag
    49621 attccttttg atgaaatcgg ctttattagt atgtttcttt ctatcaatct aggagaaagt
    49681 gagcctgtta aagaaaacaa agtagatgtt ctcatattga tgcacggcag acagactgct
    49741 tcaagcatgt tggagatggc acaagaacta ttaggaacaa aagtagggaa agcttttaat
    49801 atgccactgg ttatggaagt tcaaacaatg tatgaagaag tgttacaata tgtcaaaaac
    49861 tatcaagagc atttgacgaa tggcctactc ttgttaacag atatgggatc attaaacacc
    49921 ttcagtgatt tgatttatga agagactggc attcggacga aagctatcac gatgacaagt
    49981 accatgattg tgatagaagc gatacggatg gcaagtgttg gaagaagctt agaagatatt
    50041 tatcaaaata tccagctttc ctttgaatcg atcgtacgtg atcagttcaa agcggaaaag
    50101 tctgaaactt tacagcgtaa aaaagccgta atcgtgacat gctttactgg tgaaggagta
    50161 gctgccaaat tatatcagcg tattatgcca gtgattaatc aaaataaggt agaactgatc
    50221 cagatgcagt ttttagaacg tgaatcattc aaaaaacaca tcgatgcctt attggaagaa
    50281 tatgagatca aagcaattgc gggaacagtt gatgttgatt atcaaaatat cccatttttt
    50341 tcagcctatg acgtttttga tgatgaaaaa ctaaatattt taaagcgtat agctgatgat
    50401 gagatcccga cagctaaaat tgtcgattca cttgctggat cattaagcga tgtcttttct
    50461 attgatgaac tgatccgttc attgcaaaag acagttcagc agatccagac cgatttgtcg
    50521 attatcgtgg aacctggagt agatactgga atcgttatcc atttagcctt catgttagac
    50581 ggattgatca aacaagaaag ccatcggcaa tttgagaaac tgtctatttt ctcaaaaatt
    50641 tatcgtttgg aaatggatat cgttcgggca aacttgatgg cactagaacg aaaatatcag
    50701 gtaaaaattc cagaagatga tatcgcattt cttacacaaa tgtttcttga aaataaaata
    50761 aaaaaatgaa cacactaatc atactgttta cacactaaac atctgtgtgc gcactataaa
    50821 aaagagctaa aaagcatgaa aacgctattt cagctctttt ttttattggc atgcttcttg
    50881 cgttatataa aagtgtaaaa aaataaaagg agtgttaaaa atggcaaaaa aaacaatcat
    50941 gttagtttgt tcagcaggga tgagtacgag tttattggtc acaaaaatgc aaaaagcagc
    51001 agaagaaaaa gggatggaag ccgatatttt tgcggtctct gcctcagatg cagataataa
    51061 tttagaatct aagaatgtcg atgtattatt attaggtcct caagtacgtt tcatgaaagc
    51121 tcaatttgaa caaaaacttg cgcctaaagg tattccatta gatgtcatca atatgcaaga
    51181 ctatggcatg atgaacggag aaaaagttct tgcacaagca gaaaatctaa tgaaataaat
    51241 caagtatgca gttgggggta taacaacgtg gaagatcaac aaaatctaga agccatcatg
    51301 gggttaatca tgtttggcgg taatgcaaag agcgatgcaa tggaagcgat tgcggctgct
    51361 aaaatcggtg attttgagtt agcggatagg aaaatcgctg atgcagaaga atcacttata
    51421 caagcgcatc atgcacaaac agacatgttg acacaagaag cacaaggaaa tcatatgcaa
    51481 gtgacattat tgactgttca cagtcaagat cacttaatga catctattgc gtttactgat
    51541 ttagcaaaag aaatcatcga actttatcgt cgcgtataca gcgaataaat acaacttctt
    51601 ttttgaacgg aagaagaaaa atttttgaac ggatttttta ttttgttata aggagaactc
    51661 tctttatata aaaaacttat aggaggaagt aaaaaatgaa cggactatca agttggatgg
    51721 agaaatacat cctgccggtt gccgcaaaaa tcggagcgca aaaacattta gttgctttgc
    51781 gtgatgcttt tatcggcata ctgcccgcaa caatggcggg atcagtcgct gtaatgatca
    51841 atgcaattat tcgtgattta ccgcaacagt ttaacagtac ctatgctgac agtttagcag
    51901 cagacaaagg aatctttgcc gtattgaatg tcatcatcgg aatcaatggt tttgtctgga
    51961 acggtacact agcaatcgcc ggattgatct ttgccttttc ttgggggtat aatcttgccc
    52021 gagcttatgg agtaaatgat ctagctgggg ggatcgttgg tttagctacc ttgattcaag
    52081 gtatttcctt tggtccagca ttatcagcag cattagatgt gaatgttcct tcaaatgtcg
    52141 cagatgcaat caatagttct gagattggtg caacgattgc agatggcaca ctgtcagttg
    52201 gattatgggg ttggctaaaa ctagatcatt tgaatggaaa cgcttatttt acagttatga
    52261 tcatgggagc tatttcagtc attatttttt gtaaattgat gcttgccaac attacgatca
    52321 aaatgcctga ttcagtacca ccagcagtat ctaaagcatt tgcagccatt ttaccagcga
    52381 cgatcgcttt atacgtcatt gctattatca attatatcgt aggtcgtgta gctgatgggc
    52441 aactgatcat tgatttggtg caaaaatata ttgcagaacc attcctagga ttatctcaag
    52501 ggttgggagc agtattgatc gtcacagtat ttgttcaagt attctggttc tttggtattc
    52561 atggatcaaa tgtattggca ccagtgctag agggaatctg gggacaagca caactaatca
    52621 atattgatat tttccaaaaa ggttataacg gaaaaactgg tacaccagcc gtgttagatg
    52681 caatcgaaga tggaaaagct tatatgtggg tccgcggatc gttcgatgct tttgcatggt
    52741 ttggcggatc aggcggaacg atcgtcttac tgatagctat cttgattttc tctaaacgtg
    52801 cagattatct aacagtagct aaattatcca ttgggcctgg tatcttcaat atcaacgaac
    52861 cagtgatgtt tggtctgcca atcgtattga atgcaatcat gtttatccca ttcttgattg
    52921 ctccagtagt agcaacagca attggatgga cagctactta tcttggccta gtcgctccgg
    52981 tatcgcagca agtcacatgg gtagtaccgc cgttcttatt gtcattctta gcaacaggag
    53041 cggattggcg ggcaccgatc gtaacattag tatgtatggt cgtgactttc ttgatttggg
    53101 caccatttgt catctctgca aacaaaatgg accctgccgc aggcgaacaa caataagatg
    53161 aacgtgagga gcgggacgct ttaagtttcg ttcctcataa tgaattttcg aggaggaact
    53221 gaaatgatta caattgccag tgcaatgcaa caagatgaaa tcaaagaatt gttagaagga
    53281 tacaatgaag aaggaatgac ttttacattt aaagaaaaac aaggaatcaa gctgttcttt
    53341 gaaacaagtg cagaagatcc ggaagttgcg gctaaaaaag caaaggaact aatcaaagca
    53401 cagccttggg gaacagtcct ttattttcaa tcaacagctg tttagaaaat ggtttaaaaa
    53461 gataggatgg ttgagatgat aaaaaacggt ttatttttat gtagtattgg ttctttgatc
    53521 gtgttgtata gtttgaatcc acattcgcaa aggtatgatt tgtatagtat ggtcacaggt
    53581 ctttttctaa caggattagg aatctatttc ttcatgaagg ggaaaaaaag agaagaagca
    53641 aaggagaaaa ataactaatg gaaatcacga aaaaattaaa tattccagca tcgttttttt
    53701 acgataaagt tatggactct gtccttttcg atgtacgtaa agcgaccggc aaatcagtaa
    53761 ctagaaaaca gctgaaaaat ttggagtacg tcaaacaatt ctcgcaaaat aaccgggctc
    53821 gcataaaaat cgaagaagtc attgaaaacc agtcttataa gtttcgtaca tcgacaacga
    53881 agaatgaatt cgtcgttcat tatcaaatca aaccattgga cgattcgacc tgtgaggttc
    53941 attacacaga aaaaatggag tcttatggca tgcttcaaaa gttgaatgat atgcttttag
    54001 gaacaatctt gatgtatttt aaacggagac gtttcaaaaa aatgctagat atgatcgaag
    54061 caacgtatta aatcaatgaa acatggtact atttagttat tgaaaaatga agtaagctag
    54121 aaggaatttt tcataggaag atagatcttt cctgcgaatc ctcactagct tttttgtagg
    54181 aaggggcagc aaaatgacaa acaaagtaag agagctaggt gtatcttcga ttgaggaaat
    54241 gtttgattta gccacttatg catttaatgg ggcagataca cctgaaaggc gagaacgttt
    54301 tcgtacactt gcggagaatt cttggaatta cggatttttt gatgaggagg atcggctaac
    54361 aagtcaagtc atggcgaccc cttttccagt gaatttttac ggacaagagt acctaatggc
    54421 cggcattggc tatgttgctt cttatccaga agcaagggga caaggcggga tcaatcagat
    54481 catggaaaag atccttgaag attgccgtga tcgtaaagta agcttatctt atctggcgcc
    54541 attctcctat cccttctatc ggcgctatgg ctatgaacaa tcatttgata aaatcagtta
    54601 tcaactaaac agtcgtgatg tgccgtttat caaaaaaaaa tctggaaaaa taaagcgtat
    54661 ggattttgaa gatgcaaaag ctgcaatcag aagaatttat gaacagatgc cggaaaacca
    54721 acgagctggt ctgaagcgcg aagactggtg gtatacgtat aaattcaagc aaaaaggcaa
    54781 ttaccagttt gctttgcatt ttgatgataa tgaggaagca acgggatata tcgtttatca
    54841 gcttgcaacg tcttccttta ttattgcgga gtggggattt ttggatcatg atgctttttg
    54901 cagccttgtt cgcttcgtaa gttctcacaa tggtgctttt gaaacatttg aatattcatg
    54961 cggctacggc ggtaatgatc aaaattatct attagaaaat ccatttgctt ctgtaatgat
    55021 cacaccttat atgatggcga ggatcgtaga tatttctttg tttttggaaa attatccatt
    55081 taaaaagaga caagctgcat ttgccctaca aatagaagaa gatcattatg cgaaatggaa
    55141 tgaaggaatc gtggaagtaa caatcgaaaa tggaaaaaat catctctcaa aagtagaaca
    55201 aacaaaactc ccaatcgttc gaggaagtat ccaacatatc acgcagctat tattagggta
    55261 tcgtaaagtg gaagagttgg tattccaaga aagaatacag gtgacaaaag aatatgaaga
    55321 aacgttaagc tcaatcttgc cacagcaaca gccaattctt aatgactatt tttgataaaa
    55381 aacgggtgat gacaatattt ttgtcaccac ccttttgttt ttcatttggc atttgaagga
    55441 aaatgttaaa gtaaatcctc ttttttcgta aatttgaatt ttttgttttc ttttgtttta
    55501 gggttttctt ttttgtggtc ttggattgct tctttcgtaa tcttttcccg atttttttta
    55561 gatgaatcta agcgttctgc gtatactttt tcttttggct tatcattcat tggaaaggac
    55621 ctccctacat tatttcattc tacctctagt ttatcatctg ttaaggacta gtggaaacgt
    55681 tttgcctaac ttataagctg atttttttag cagataagct tgcaagtaaa aaacaaacaa
    55741 gctacaattg atttattgaa attgttcctg tagctcagta ggatagagca atcgcctcct
    55801 aagcgatagg tcgctggttc aattccagtc aggaacgtat aaataacccc tgtatccttt
    55861 gcggtacagg ggtttgtttt gtatttgtgc caaaaatgtg ccaaactagt tatcattttt
    55921 atataaacta tcgaacacag tattgatttt ttctttatcc tgatcttcaa gctctcgaac
    55981 aatatgaaga taagtagaca ttgtagtttc taaactgcta tgtcctaaac gtttcgatac
    56041 gctaagtata tttactcctt gataaagtaa aatagatgca tgtgtatgcc ttagtccatg
    56101 caaagtaaat tgcttttcaa tccctaattc ttttaatttt ttgcgcaaat atttgctgac
    56161 ggcgtttgat gaaactaatc cattttttaa gttgaaaaaa acaaaattat gagggttttt
    56221 gatttcaaaa ttctcgaata attctttttg attgatttta aactttttta agagatcaat
    56281 cgtatgttta tcaatggaaa ttttcctatt tgaagtttcg ttttttgttt ttccccattc
    56341 atttaattta taattccatg ttttattaat agtgatgatt tgatcttcga aatcgatatc
    56401 ttcccatgtt aatcctagaa gttcagcaaa tcgcattcca gtggcaccag caactaacac
    56461 gagcatagga gaagagtact gcgcagaaag gttttcttct acgagtttca ttaaagattt
    56521 aaattgatca taatctaaat atttatcttc ttttggcttc aatgaatctt ttcctttgat
    56581 tactgctttt ctagttggat caaacggaat taatccttct tctacggcat ctttcaacga
    56641 cgctctaata tggttattaa acttaataac ggtagatttt acatggtctt tagcatactt
    56701 atttaaaaag cgttgatatc ccactctatc taaatcagaa atcaataccg ctggcatata
    56761 tttctttatg ttcattaacg tatcttcgta ttttctataa gtgataggag atactgttcc
    56821 ttctttataa agttgcatcc aatcctcaaa gtaatctgat aataatagat ttttgcgatc
    56881 ccctttaagg cctttgttca agttatattc taattcgttg gcggcatctt ttgcttctcc
    56941 ttttgtctta aatcctgatt ttcttatctt cgtgtatttt ccgtcatctt ttttgtatga
    57001 aatttcgtat tgccaactat ttccacgttt gactaatctt gccataattg aatcagctct
    57061 ctttctctga tacaatagga actataaaga agcccattgt ttgggtttta ttattttttg
    57121 cacatccttt ttgcttgccg gcgcaaggat gtgctatttg tcgttttaat ggtataattg
    57181 gatgtgtatt agatcatcca atcagaggtg tttattatga ttaaagtgat ttttaaaaga
    57241 ataactgaac ttccagagtt tagattattt gttgattatt ggtatgtctg gttttttatt
    57301 gttgcattgc tgataggtct agatgtcata ttagaaagaa aacttaagta agagttgagt
    57361 taataaattg aattcctaaa tgagatattt tgtagcccat attttgtttg ccgacatcac
    57421 ctaatactat ggagctaatc gttttttcta acagaccaaa atcagataat ctatttaagc
    57481 taccatctat tagctcttgt gaatagccag acatgctgat atttccagtg aaattttcgt
    57541 ttccacgact cattaagcat gctaacaatt gaatctcaat cgatgttaat tgattcagta
    57601 caagaagata atactcctcg ttatcccatg aagcgttgtt aattcgaagt aaacaattct
    57661 tataaagatt tttatacata tctattttat tttgtgcctt tgatttttct acctcgtcat
    57721 ttatcccttc gaatattcca atgagttggt ccttgttctc taagttgaaa acatcttctg
    57781 gaatttgatc gcgaatgttt tctaatgatt cgtttaaatt tttgtagaat ttctcgatgc
    57841 gtttgaaacg cttctcgttt ttagacccaa aataaagtga ctgcacaacg ccaccaatat
    57901 aaggaattgc tccaataccg ccttcaacta ttaattcaag atattctttt ttggttagtt
    57961 tttcattgct attatccata gttacctcct attttgtcat ttcctttaca agcattgtga
    58021 ctcctgatgg cactcttttg tataggtttt attattgtgc acaatctaac tcttagtggg
    58081 gcgtggttca tttatttttt acttacttta ctattaatca tatcccattg agcataggat
    58141 ttttctatgt tcgatcctct tgaactaatt tctcctgtaa aagttacttt atcgcccttt
    58201 gtaaaggtat cagcattgtt taagtccttc gcaaaaatta catatgaaac tttaggtgtt
    58261 gcagaaatat cattccaact tttatcatcg tactctttgt ctgctataat ggctattcta
    58321 gtagtcattg attcgataac agttccttca aaagtatatg ttttaccact aatatattta
    58381 gtaaaagctg tattttgctc agtagctgga gtaatagaat aataactatc taagaaagca
    58441 ccccagtcat gattatttgt ctctaaaaat tcttcaaatt gagttaggct tttattgctg
    58501 ctgttagatg tagtagtttg agtatcagat gatgagcttt cctgtttgtt attgtcattt
    58561 gcctcgtttg atgaggaaag cgagaaacct acggtagtaa aaataatccc gataataagg
    58621 agaatcatag gtgttttctt atttgttttt ttgataaatc ttacaattaa catgattaaa
    58681 cctataataa ataaaacaat accagtaaaa ccaaatatac cgtccattaa tagatcctct
    58741 ttctcttttg atattgaata ttataaacca agcaattctt ttttcttaaa atcgaattct
    58801 tcttgattaa taatcccttc atctaacaac tctttatact ttttaatttc atctgcactt
    58861 gaaatttgtg tttctttgga attattatct aatatagatt gttgcttctc tatatatttt
    58921 tttaaatttt ccatttcatt ccaatatttt tttgtaaaca taacggtgtt ttcatctttc
    58981 gtggccgcta atatacctcc gcgactttcg tttccgccta gcaaggtaaa ttgtatataa
    59041 ccattactca tacctggttt ttttaattgt acggctgata tatttttaaa ggggatagtt
    59101 ttttctcctt taataccttg attaactaaa tttataaatc cttttctaat aattgaaata
    59161 gaatcatcag ttactttaat caaggttttt cctggagatt ttattaaaat ctctttttcc
    59221 attttttctt cctcatttct gtgatatgat tttttttgta gaagctcata tatgaggaaa
    59281 gagcccgtgt tgcagcacgg gcttttttaa tgttttgctg aaatcggttt ttttaataat
    59341 tcttgatgta ttcatacata ttgccttgcg taagaatatt ttttcttaaa atagcattgg
    59401 cagacagcat aacaagtgta tctgagctta ttctgaatag aataatactc cataaatttt
    59461 tcgagattaa actgagattc atcagtcagt tcgttctcaa tatagatatt taataaaatt
    59521 agaatagcta ttttatctgc ttctgtttca aattttgagt gaaaagttgt agaagtatcg
    59581 tacaaaactg aaaattcaaa atgagaggcg ctgaaatgtg caagttcatg agataaatga
    59641 aaggcttctg cagtttcacc gtatagattt tcattcaaaa aaatgattct gggttttgga
    59701 tagtagaaac caggctcttt catctccata taaactactt tcaaattgta ttcgctcaac
    59761 atttctttca atttcaaata catacaaacc atcactccaa ctattcattt tcctctaaag
    59821 ctttagcaat tgcaatcgct ttacgcattg tctccttaga tatttctttt ccatcaaaag
    59881 aaaaaacagt atcgtcttct gataaatcca catgtttagg ggtttctctt tcttctctac
    59941 ctagaaggta gtctacagag acatcgaaat agtcagcaat ccgacttaat tcatctgaat
    60001 taggagtatt atttttccac tttgctagat aaccgttaga atatccaaaa ttaatttcta
    60061 actgccgtat agatatcttt ttcctcttcg ccaagtcttt tattatttca taggtattca
    60121 tcgataaaac aacctttcta aatgtttaca aaaaaagttt agaaaaatac gcagaaataa
    60181 tttgactaat tctgagtaat gagctatact atatcttgta aacagattta acaactaaaa
    60241 agacaacaaa aaacactatt gatatgtaaa tgcagaccgc caagaaagct ttaaaatcaa
    60301 tgtttttatg tcttatttaa ttatgctctt agtatagagt attactcaga tactgtcaat
    60361 tgaatttaga aaaaagttgt taaatttgtt tacgaatata aaagaaagga atgagaaata
    60421 tgaacacacc gcaaattttt aatttcgaac aaaacgaagt tcggacaatt ttagtaaatg
    60481 atgaaccata ttttgtaggc aaagacgttg cgagtgtttt gggttattca aacactaaag
    60541 atgctttgtc gcggcatgta gatttggaag ataagatggg gtcgcgaatc acgacctcag
    60601 gtcaatcaag agagatgaca atcatcaacg aatctggttt gtacagttta atcttaaaat
    60661 caaaacttcc ctctgccaaa aaatttaaac gttgggtaac aagtgaagtg ttgccagcaa
    60721 ttagaaaaca tggaggttat ctaactccag aaaaagtaga agaagctttg cttaatccag
    60781 atacaatcat tcaattagca actcaactaa aagaagaaag aactggaaga ttaatcgcag
    60841 aacaaaagat tgcagagtac gaacctaaaa tctcctattt agatagcata ttatcttcta
    60901 cagattcagt aacaattagt cagattgcag cagattatgg gatgtctcca caacagatga
    60961 ataaattact tcataaacta ggtattcaga aaaaagtcgg taaccaatgg ttattgtgca
    61021 aaaaacacat gaaccaagga tacacaaaat ctcatacaac tgagatcccg aaagccgatg
    61081 gtggcactaa aattgtaatg aataccaaat ggacacagaa agggcgtcta tttatctacg
    61141 aattactaaa aaaagaagga tattaccctc aaatggattt agaggaaatt ggttagaaag
    61201 gagttttagt atgactgaca ttgcagaaat cactcaacga gatagagaaa aaatcaaaga
    61261 atatgtcgaa agttcaaagt tcttaactta caccatgctt gctgaaagat ttggaattag
    61321 caaaagctac ttatctttaa ttttaaacgg taaaaagact tctgcagaag caaacagaat
    61381 tatagattcg attatcacta tgtacgaatt gtaaagggag gaacagctaa tgcaatatct
    61441 agaagcaaaa atcccaattc cagaaggcta tgtaattatc tcccaagtgg attatgagga
    61501 gttaaaaaaa gctgatgata ctggtagatg gatgacgttg ccagaagtgc tagaacggat
    61561 taacagaaaa tatgattggt ttacttctag agttttaaag aacccaagat atagaaatat
    61621 tatcgatatc gagaaaaaca aaaatggatt tgtctattat ccagttgaag gaagagacac
    61681 atatctattt ttaagaagta aaacacttga atttttagaa acaaattttt cggaaatctt
    61741 aaggaggcaa gcggatggga aaatttaata gagcgctagt gttcagcgca ccgctaatca
    61801 tctacgcttt aggactttgg ggaagcaggc aagcgttgat aggaacgatt gtttacatgg
    61861 tttggatttt tatggggctt gatgaagctg aagctgagta cagagcgaaa aagccaaccg
    61921 agggggctga ctaaaaatga atagaaaaga gaaactagaa tgtatattac tattactcag
    61981 tttaattctt tcactaattt ctctattggg aagtttgtat ttttgatatc aacaattttg
    62041 tggatttggg ttctatttag agtaaatatc atttttgttt ggtgattaag gagtttatta
    62101 aaattaattt tccctacttc aaatgcaagg taacaagata tagcactttt aggaggaata
    62161 tttagcggta cagcttcaga gtatattcta ttatcatcga ctgatcctcc tttagcaatt
    62221 aatttcttaa atggagtagc tgaccatctg cggtttaagt tagcggatga aagttctaaa
    62281 ttaactaaca tagctggttc tgttgaatag ttagaaatga ttacttttgt ataaatcata
    62341 tctgcagcga agtaagaagc attaagttca acttctagtt gagggcgcat tccttttatt
    62401 tttatccctg ttaaaaacgt actcaatata aaacttatta ttgacatcca ttgaaaaatt
    62461 gttaagtgaa aaaaattcaa aataaacacc accagttttt aactaaatta taccaaaaag
    62521 gagagaagaa ataatgcaag aattagtaat tttgaaaaat aaagaagctg tgactacgag
    62581 cttacaagtg gcagaaagct tcgagaaaaa acatcaacat gttttaagag atattgatgc
    62641 actaaaaaaa gatgtgtcca attttggaca gatgtttgta gaaggtaatg aaccagattc
    62701 atatggcaga aatcgacgag ttttcttcat tagtagagat ggatttttct tgctggctat
    62761 ggggtttaca ggaaagaaag ctatctactt caaacaaaaa tacattgaag cattcaacga
    62821 aatggaagat gttattcgca agaatactgt tcctcaaaca attgaagata tgatgatcta
    62881 tcaattagaa gaaatgaaag atgttaaaaa agatgtttcc atgcttaaag atactatgcg
    62941 aattagcgga caacaagagt ttgaaattaa gcaaaaagga aatatgaaag ttatgggagt
    63001 tctaggggga aaagaaagcc gagcttatga agaaatcagc aaaaaagtat tctcaaaatt
    63061 ttggtctgaa tttaaacgta ccttttcaat cccaagatat ggcgagttac ctcgtaagag
    63121 attcgatgat gctgtttcat ttattgaaat gtggttgcca gaaactgcga tccgtatgga
    63181 aattgatcaa ctgaacagac aacagagact ttttggtgat gacaatgaat agagctgaag
    63241 cgctaagaat agggacggca attgctaatt gctggtggaa atactataaa ccaatcatcc
    63301 taagccaaca acatattgac aagcaaaaag catggcaaca aataaaaaag tgactccgcc
    63361 ggcaagcaaa gagtcacaaa gaaaacacat cataaggaga ttttagcata tggaaaaaga
    63421 actttccact ctagatcaat atttgattga tcctgattgg ggcaagccga aaattgagga
    63481 aacaagtggt cgaaaaatca gacgaaatct tttgacgaat gaagaactag cttgggatca
    63541 agatgattta ggcaaccatg taactatttg ggatcatgtt tatcttatcc atctatcgaa
    63601 gcattcgaat aaacctgaat atatttacgt catcgaagat ggcttgattg atgcgctaga
    63661 agagtacgac agagataact tgattgatat ctcttattac ggaccaggta agaaatacat
    63721 tgctgaaatg gaggcagaat ttgatgagtg aaatcaaagg gacaacgaac tttgaaaaac
    63781 tttttagtcg taagttaaat aaaattctca agaaaaaagg aaattttgat tatttatctt
    63841 gggctcacgc gtgggagatt atgaaaaaga atgatccaca ggcaacggta actattaatg
    63901 agtacaaaca ctacagggtt gtttctggaa ctcatcaaga ctttcttgtt gaggaatata
    63961 aaccttttct tatggatgaa actgggactt atgtatctgt ctcagtaacg gttaaaggac
    64021 acacggaaac cgaattattt cctgttttag attatcgaaa ccaaccagtt gttaaaccaa
    64081 atgcaatgca aatcaataac tcattgaagc gatgctttgt gaaagcattg gctctacacg
    64141 gactgggatt atatgtattt caaggggaag atattccaac accacctaga atcgatacaa
    64201 agaaattaaa catgctagag acgattctag aagctttcaa tgagcagatg ggtaaagata
    64261 tgaccaaaac cttaatcgaa tatgttaatg agcagacaga taaattaggg ctcttagctg
    64321 ataacgttga aactattgaa cagttaagct atgagcaatg tgccttgatg gagcgagcaa
    64381 tagcagctaa gagaaaagaa ttagataaga agtgatatga gtgtttaaac cattaatcga
    64441 ttcatattca gcggttctga aaaagttcaa aggaaaagac ataagcgcaa ccatcaatga
    64501 ggaagtgaac attgatcgac taaagacgat gtatgacggc tacgatggtg atcgagtcat
    64561 tgaaattcgt tttattgatc ctagacgttt caccgtacag caacgaaact tcatctatgc
    64621 gctgataggc gatattttta tcgatacagg catgccaacg gacttctgga aggaattctt
    64681 ctactttcgt tttgaaggtg tcacagggcg caaaataagc ctgaaagacg aatcgaatac
    64741 aactgtgagt gatgccaatg tcttagcaaa tatcatctta gatttcatct ttgaacatca
    64801 tattcctttc aaagaaggct atgagatttt acctgcgaat caagaatatt acttctacaa
    64861 atgcatcaca aaaagagtct gctgcatctg tggcaaaaca ggagctgaca tcgatcactt
    64921 tgacaaagcg ctaggaagac gaaagcgcaa agaagttgat catgcagagt acacatttgc
    64981 agcactctgc agaatccatc acacagagaa gcacaaaata ggtgtgatta atttcaaaaa
    65041 taaatatcaa atcaaaggga tcaaattaaa ccagaaaaca atcaaaaagt taaatattgg
    65101 aggggaaaaa tgacagaaca tcgaagttat tatgcgatta taccagccaa cgtaaggtac
    65161 gacaaaagac ttaaaccaaa tactaagttg ttatacggag agataacggc cttgtgtaat
    65221 gaaagaggct tttgttgggc aggcaatgag tactttgcag atttatatgg tgtgaataaa
    65281 gagaccatat cgcgatgggt aagtgatttg attaagtttg gatacttgaa tcgggaaatc
    65341 atttacaaag agggtaccaa tcaaataatc aataggtacc tacgaattaa tcaataccct
    65401 attgacgaaa aacgcaatac ccctattgac gaaaaagtca aagataataa tacatctatt
    65461 aataatacat ttaataatac aaaagaatat ataagagagt taccgccttc gaaaaaatcg
    65521 aaggctaagc ccgtccgtca taaatacgga gagtataaaa atgttctttt gtcagatgag
    65581 cagatggaga aactcaaaac agaattccct aatgattacc aagagcgaat cgaacgactg
    65641 tcagagtatt gtgaatcatc tggtaagact tataaaaact atttggcaac tattcgaagt
    65701 tgggcaagga aagaaaaaag tgaacctaag aacgcaagca gtggatacaa gcgcacagga
    65761 agacgagaga agcttcctga atgggcaatc gaccaagaag cctatctcaa gaaaaaagcg
    65821 ctagaacgag ctaatagaca atcaaaagca ccattctaag aggtggaaaa atgaagatcg
    65881 attatctaga actaattaat gaaatagcga attataaaaa gggcgaggaa ttagacgtcc
    65941 tgagagacgt atatgatcaa ctcgaagaag ctggaattga aggaattaag aatgatcgtt
    66001 cgagttggag taaactcaga tactatttcg cactctatat cgatggaacg caattaagaa
    66061 atttagcata taccaaatta ctattcattg attgtgttaa aggcttgcaa aaacatctta
    66121 atgaacttga gcaggtgtaa acaagatgga cctaaagaca tttacagcac agatcgaatt
    66181 aatgcatcaa gaagctttaa gacaaagtgt gtcgtacgaa gacaagtggc tcaacacatt
    66241 tcatggcgga cgtgagagcg cacttgatca agtactcaaa ttactgaaag gagaatgtcg
    66301 ggatggataa gaaagcggca atgcagcgaa ttatcgaatt gacttattca gaagattggc
    66361 aggaagataa aaaaatagtt gcagaagtcc aaaagctcgg taaatcaatg tggactgaaa
    66421 agcccaaacg gagaacgccg agaaagattg caatctggca tggtgatcga attctagtaa
    66481 cgggtaccgc taaacagtta tctgaaatta ctggtctgag caaaaatatt atttgggata
    66541 gagctaggag cttatggatt gattcaaaag gaagacagtt taggtatgtg gaggagaaat
    66601 aatggacgaa ctaatcgcga aagtagagca gtgggcaaaa gataagggat tggatcaagc
    66661 ggatttcagc aagcaaatgt taaaaacggt cgaagaaatc ggggaagttg ccgcttctct
    66721 agctagaaaa gatgaacatg gtttaagaga cggaattggc gatgtagtag taaccttgat
    66781 catcttggca atgcaaaatg atatggattt atacgagtgc ttggattttg cttatgacga
    66841 aatcaaaggt cggactggaa agatggtcaa tggtgttttc gttaagtcca gtgacctgaa
    66901 ataattccat taatggaaga aataactgaa taggaggata gacatgattg atgcaaaaca
    66961 agtgcaaaaa cagaaagatg gaatgttgat gtttgaagca tatgttctac catttcttaa
    67021 tcaatttgaa gttttggaat gctctgccag cggagaagaa ttggagtatg ttgtaattcg
    67081 tgaaaccaaa gaaaacgttc agaagctaaa cgaatttctt tgcactatta actgttggga
    67141 tatgatagct ccaggatttt tatgtccagc tatgggagaa tttttggaat attgtcgtct
    67201 tgaagatgca ggcactttgg atttagctta tctggtatac aactacctaa acatcaacac
    67261 agatcatttg tggtttggca ctgccgaaag aaaatgggta gtccgctaac caccaatatc
    67321 aatgaaaaaa ggcggtttcc tgaaagtgga attgccgcca ttgctgtaag gttctttacg
    67381 cgactcaagg tcacagaaat ataaatgcaa atctcttttg aagtgatcca aagctctcgg
    67441 aaaatggaag ttttttgttt caaagaataa atgagatttg cgtcaagaac ctgagagtta
    67501 tttccaaaaa agcttccaaa gaaccgaatg agctaaggac atcatgtgta aacacataat
    67561 atagctctcc tttcacggct aatcataaca tgaaaaatat tcgatgtcag taggaaaaaa
    67621 ggtgaattat gaaaagaata ttaaattatc ccggcagtaa cagattctgc aattaaactc
    67681 cgaagctgat gtatcagtat caactgtaga atattatgag cgtggagaaa gtcaagcagt
    67741 cacaaatgta aaaatcgata acgtcaacgg tcttatctgt ttagatgaag gcgatagtat
    67801 gaatgaaatt gctgcagacc atgaattatc agaaactgct ttaattgatc aaatcgaatt
    67861 agctagacaa tactttgttc catatgcaga tacctggtcc aagcataaga atgacatcat
    67921 ttttccagag gaacaatgag agcaactgat ccagtaatta tccttgagga agccaaattt
    67981 atttggactc acgaagagat agagcaagca cgcttgctct tttctcaagg agttaagccg
    68041 agcaaagtag ctgaaataat gggtcaaaag attcttgatg tcggattgct tttgctccat
    68101 ctagcagaaa aaatttgatt tgaggtgaaa atgatgattc aacttgcagg catccaaaca
    68161 gggaaaattt atttttctgg agaaagcaaa agcgaagcca accaatggct attgaaaact
    68221 tacacgaaca ataagaagct aaggaaaaaa tatcctgatt tgttgctaaa ggatgatcag
    68281 attatgccgg aaccgatgat tttgacccgt aaggagggaa gttgaaacta aaaaaccagc
    68341 cgtgtgggct ggagttgcta tttcttttta ataatgagtt tttctaaatt taattcattc
    68401 tcacgagttt gcgtccaata atcagaataa tattttaatt gtttaagagt aggaatgtcg
    68461 tcttcggtaa aattagaaaa taattctgga gaattatctt tttttaattg ttctaatcct
    68521 gattctttaa aacgttgttc aacgagtttt actaaattgt tgatattcat gataaatcac
    68581 ctttttaaat ttaatttcga tttgattaat cgatacaagt attatatcaa ataaaaaagc
    68641 tgatttaggg ggtcttacaa aaacactaaa attttttcaa aaagaggagg aacggtggtg
    68701 aaagtcagag aacaattcaa gatagtgagc gacgaaggta atgtttacaa aataaagatc
    68761 gttaatatta atgaatatcg agaagcagat cacaaatatt tggttgactt atacatgaac
    68821 gataaatatt tgggagaagg attttgtgga gattcacttt ttgatgatga gcgaattttg
    68881 aaggaggaaa cagaatgatc cacgaactaa aaatactacc agaatatttt gaagcagtga
    68941 cgagcggacg caaacaattc gagatccgca agaatgatcg tgacttcaaa gttggtgatc
    69001 agttaatact acgtgaatat aaaaaataca ttaaacatga attacctgga ctaacgagac
    69061 caacatttag ttacactggt gactcataca aagcagagat cacttatatt actgattaca
    69121 tgcagaagtc cggatatgta gtgttgggga ttaaaggggt gaattaaatg aaagtataca
    69181 tcttagctat cacagagggc acatggatgt tcccagtcgg ttccggaaaa atctataaat
    69241 caaaaacagc tgcttataaa gcatttgaaa aatacaaaaa agaaaacggt ggcggcacta
    69301 acgcaaagat tctagtggct gataactggc atgaagaagg tgaacgtaat tgatttacct
    69361 gttcattttc gtggtactaa ctatttttat gctagtaatc ttattcaaaa aaagatgagt
    69421 aaagacgaac gaaaaattct ggccaacttt tatttagtat taaaaatcga acaaaatgtg
    69481 ttttcggaaa ggagaattgt atgggaaaaa caaaatcaaa gattaagaag aaaaaacgac
    69541 gtttggaaca aaaggcaatc cagaatggaa cggctaagaa aaaataaaaa agctacccct
    69601 ttcgagatag cagcgcaata ctattctacc ataaggggtg gcgtttgtga gatttcattg
    69661 gttaaaagat taccaagaac tagatgagca gattctttac ttaaagtgga atcttaataa
    69721 aagtaagctt gaattgaatc gatgggtctg tggtgattta gcaaacgtcc gcatcgaaaa
    69781 gaattcgaga acttcttctt tagaagagaa tatccaaaag atagaaaatg aattggaatt
    69841 gttgatcgag caaaaagaag aaatgttatt gctgatagat agcttttctg gtatcgataa
    69901 tcaaattgtt aagatgaaat atgttgatca aatgagctta gaagatattg ctgaatctgt
    69961 tgggtatagc tcatcgtatg tcagacagcg acatgcagaa attagaaaga cattgaactt
    70021 tttagatgag tatgaacaca gacaagctga ccgattgaaa aaagaaaacg aaattgattt
    70081 ttacaatagc gagaagtaca aagaacaact ctctttattc taaaattaca ctgttcacta
    70141 aatgttcgta aacattgtta gcagcatgat attctattag tgtcaaaaaa atatgaaaga
    70201 gccaagatat cccaaccgtt ttattaattg gtatctgtgg ctcttttatt cttttaatta
    70261 gtagttggca taaagttatt tccatttata aattgatcag ctaaatcagc atcataatca
    70321 gccgcgataa attgcgctgc tgatttaata aatgcatcca tatcatgaac atctttatta
    70381 gtatgtctac gaacatagtg cgtttcatca ttaccaatcc aagtagcagc tttggctaat
    70441 ctttggagtt taggaaaatc attcaaataa ttttcaattg ttttacctaa taacattttt
    70501 tttattttat cttcatcctc tgaattttta gatattgcat aatctttaat tagaaattct
    70561 agagcttttc tataaccaac tccagcaatt tgttccaatt gctcagattt agcttgtgtg
    70621 gcttgagtat aaatatcaac aaatgtagga gaaacttttt caatattttc tggtaaatct
    70681 attttaatcg gcggacggta ataatcttta attaaaatat tttcagaata tccttcatct
    70741 tcattaaacg tatttataaa ttgtaaacta taaaatttgt tgcactcatc atttatacac
    70801 tgtactaata cgccaaagat tctatcatta tcgaacgcac tatatgatga aaccccaaaa
    70861 tacacatacg gagtcattat atttccgcaa tgcggacaac tatttggcaa ataaattgtc
    70921 tctgtatttt gacgatcacg atacttaata ttaacttctt gaagcattaa aacacctcgc
    70981 atctttttta taaatcatac cacaaaatat ctgataggag agtaaacaaa tgaatgattt
    71041 tcatgaagcg gtacttagta ttgaagtaga atcaagtttg gctaaagttt ataagaaagc
    71101 aattgaagca gagaatagtc cgtacagaga aaattggaat ggtaatcatg cacatgtgca
    71161 agtggagaat gatgattaca gaactggaat gaatacgtta gttatttctt tattgtcaca
    71221 cactctaccc aatctgcagg aaacgattga atggtatgag cgaatgggcg caaaagtaat
    71281 ccgtacaaat tacaaaggag agaattaaaa tggcaatgat caaaattaga acatccatta
    71341 gtggaacaga gtattgggat tcagaaaaga aaaggacagt agttgttccg aaagatcaag
    71401 aaccaaattt tgaagtaaaa gaagaaaaag gaattttgag tgatggcaaa tcatttgttg
    71461 ctgtcaatgg cgaactcata gctcatagca gtgaaattct tgatagcgat ggaaacactg
    71521 ctgctaattt tgatggagac gaagctacta atgatcagtc cactgaagat acggatgaac
    71581 tggacaatat gactgcaaaa gaattgcgtg catatgctaa gaaacatggt attgatattc
    71641 ctggtgctat ccgtgcaaaa ggcgatatca taaatcttat tcgtgaagta gaatgaaata
    71701 ctgtcagttt gacggatgca cgaacaaaat agcaaagggt atctactgta ctgaacacaa
    71761 gagatcaagc agatcacgca agaagaagca gcaagcaaag tctgtttatc atcatgagaa
    71821 caaaccattc tatcgaacgc aagcatggaa agatatgcgt caatttattt atgaaagaga
    71881 aggtggtcat tgtcagcggt gtggtcagtt catatttgga aagagagcac acgtccatca
    71941 cattgtacca atcaaagaca acgaactgct taagcttgat ccaaacaatc tcatgctatt
    72001 atgttcaaaa tgtcatccaa ttgttgaaaa cgaaacggaa gacaaaaaag tttttccttc
    72061 gtatttcaat tgaagccccc ctattcattt tcaaaatttt ttcgcgtggg gagatagggt
    72121 agcggggagt cacgcgcatc gttaggtcaa atttttcaaa aaacaaaggg gggtgtatac
    72181 aaaaatgacg actaaagcgc aacgtaaagc gattattgat gaaaaagtaa gtgctgaaaa
    72241 agctcgtatc ttagaaataa tgaatttgtc tgatttgtac accatcactc ttgatccatt
    72301 aatcgaatca tacttggata tttttgaaat ttaccaacac aaatatttat tgtggaagga
    72361 aaaaggattt ccggagacgc aaaaattcac gaataaatca ggagctacta atcaatcaaa
    72421 acatccattg gcacaacaag tagaaacttg ggcagataag aagatgaaag ctctagattt
    72481 attaggatta acaaacaaag caaaaactgg tagactaatt gctggaggat cgaccgcaag
    72541 aaaagatgaa gaaattacac gcccagaagt aaagccagta gatgaactag cagcgcacag
    72601 aaataaatgg cgtaagaagg caggtgctga aaaatgattg aacctggtgt aaattatgct
    72661 gatttatttg caaaagaagt aagaaagaaa cctaagaagt atcctaagac cgttcgttta
    72721 gcaatagatc gctggtatca gtggaaaaaa agaaaagata tttggtttga tgtagatcgc
    72781 gcgaatgaaa tgatggattg ggtagaatca tttattgttc acacaaaagg agaaatggtg
    72841 ggaaaaccgt ttcttttaga accctgggaa aaatttattt attcttggat ttatggttgg
    72901 gttaaagaaa atgaaaaagg ccaaattgta cgcgttactc gtgaggctta tgtccagatt
    72961 ccaaaaaaga atggtaaaac attgattgct gtcggttcat taggatatgc aatgtacgga
    73021 gaaggggcgt tatcagttga ttgctatgct tgcgcatctg attttgctca agcgcaatat
    73081 gctgccaaac cttttgcagt tacaatctta aacaatccaa tcctacttga aggaactaaa
    73141 atatttaggg ggccaaaggg aactgtttct agtattactt atgactatat tcatgaagat
    73201 atggcttact caaataaatt tattgttcaa accaagaata ttgataatat cgagggatcc
    73261 aatccatatt ttgtattgaa cgatgaattg cataaacagg agaaaatgga acagtatgac
    73321 aattttaagt ctgctcagat atctttacca cagccattga tgtttaatat ctcaactgct
    73381 gggaaaggtt cgtcgtctgt tggaatgcgt gtatatcgcg aagcaaaaga agtgttgaaa
    73441 cgtgatgata atgattcaaa ctttgttcta atctatgagc caaataaaaa ttatgattgg
    73501 acggatagaa aagtctggga aatgtgcaat cctaactggg gaatatcagt cgatttatct
    73561 gctttagaat cggcatttaa aacagcgcaa cggtcagctc attccaaagc tgaatttcta
    73621 acgaaacact tggatgtatt tgtgaacggc gcggataatt tctttgaaca ggatcaagta
    73681 gagccatgtt tagttaccac acaagaactt ggtgatttaa gtggcgaacc atgttatatc
    73741 ggtttagatt tatcacgtac acgagatttg acctgtgtat ctttaaactt cccaacatgg
    73801 gatgaagatg gtaaagcggt tcttaaagta aagcaacttt attttattcc gaatgaagat
    73861 ttagagtttc gagaaaaaga agataatgtt ccttacagtg atttggctga acaaggtttc
    73921 gttgaatttt gcgacggaaa aatgattgat caagatcaga ttttgcagta catagaggac
    73981 tgcatgaatt tatatgatat tcagcaagtg aattatgatc cagcgatgag tgacaaactt
    74041 gttgagaaat tagaaaactt aggattggaa tgcgttgaag ttgctcaata tcctaaagta
    74101 ttgaatgctc cttttgacga tgtcgaacgg ttgttttatg agaaacgaat tcaatttgat
    74161 aatccattat tcctttattg cactttgaac gttgtagcaa ttactaacat caatggacaa
    74221 aaagcgccaa gtaaacgtca atcaaagaaa aagattgatg ggttcgtggc gtttttgtgt
    74281 ggtcataagg aaacgatgaa tcaaatgaca gatattgatt cagatgagtt agatgattac
    74341 ctaagttcca tctatagata aatagaaagg cggtgaaaaa aattgaaatt acgtgatcgg
    74401 ttatcgaatg cagtctattc ttttatggaa aaacgtggat atatcgagga tatttttgga
    74461 cactacacac gttatggtca aagatatgtg acggattcat ctatcatgga atcttctgat
    74521 gtttatgaat tagttcaaga catatctaat caggtggcat tggccacacc aattgttatt
    74581 ggtcccgacg gcaacgaagt caaagatcat cacttactaa atattttgaa gagtcccaat
    74641 gattatttga caggattcga atttaccaaa ttggaaacaa atactttatt gatcaatggt
    74701 gagacattcc cattaacgga tagggatcag cttcatttgg cgtacggtgt aacaactaaa
    74761 atcaatgaac gacttcaaga agaatttgaa atgaatggtc aaaaaatacc tggtcaaatg
    74821 attcgacaca ttaagaacat cggaactgat tcattaaaag gtgctggaat aattgatctt
    74881 gcaagaaaca ctctagaagg cgttctgagc gctgaaaaag ttttgacgga caaatatact
    74941 aaaggcggtt tacttgcgtt catgcttaaa ctagacgccc acatcaatcc aaataatagc
    75001 gcccaaacaa aaattgtcaa agctatattg gatcaactgg aaggaacgca aaatgagagt
    75061 gatcattctg ttaagatgat tcctttggga aaaggatatt ccatcgagac attaaaaagt
    75121 cctgttgatg acgcggcaat tttgaattat ttaggtgttt acaaaaaaga cttaggaaaa
    75181 tttctaggaa tcaatgttga tacgtatcaa tcgctgatga agacagatat tgaaaaagcg
    75241 atgatgtatc tgcacaacaa agcaatcaaa ccaatattga aaaacaagag cgaacattac
    75301 accgctcttt tttttatgcc taattctggc tatagagtgg aatggaaaat taatattttg
    75361 gattttgttc cttactcaac aaaaacaaat attggctaca acatcgttcg taccgggatt
    75421 acaagtccag ataacgtggc agaaatgctt ggttttccta aacagaatac tccagaaaca
    75481 caagctatct atatttcaaa tgacttatct aggattggcc agaaaaatgc aacagatgat
    75541 tccttaccaa cgaatgatca agacttgaaa ggaggtgatg gaaatgaaga agaaggaaat
    75601 tcgcacgatt gacatcacca atctttcaac acgttccgat gaagaaactc atacgaggac
    75661 cattagcggc tacgctgctg tattcaacag tcaaacactt ttatgggatg acttaagcga
    75721 agtgattgtt cctggtgcat tctcaaaggc aattagtaat tcggatgttc gttgtttgtt
    75781 caatcacgat tggtccaatg tgctaggacg tactaaaagc ggaacccttc gccttgaaga
    75841 agatgaacgt ggtttgaaat tcgaagttga tttaccggac acaacggtag caagggactt
    75901 agttaaatct atggaacgag gagacatcaa ccaatgtagt tttggttttg tgccgactga
    75961 agaaacgtgg gactacaatt ctgaaccaat gcttcgaaca atccatgaag tggaattata
    76021 cgaggtttct attgtgcctt tgccagcata cgaagataca gaagctgcat taagaagtcg
    76081 tgatgaatta gaaaaaaacg tcgaagaaag aaaaaaatta atcaaaaaaa ttaatcaagc
    76141 gctagaagcg taggaggaaa aatacatgga taaagaatta ttgaaaaaaa tgaaggcacg
    76201 tcgtgagcaa cgattgactg aattacgtga aaaagttgaa tcaggagaat tacgcgaagc
    76261 agatttagaa gccgtgaaag aagaaattga cagtgttatt gatgaattga acggaattaa
    76321 agacgaatta ggcgcagatt ctggaactga tgaaacagac gacaatacag atgatcaatc
    76381 gaatagtacg gattcagacg aaagccgttc tggtgaagac aacgatcaag aagaagattc
    76441 agacagtgaa gatagttcag aaaatcgttc tggaatgatt actcaacagc aacgagatgg
    76501 attacttgga tcaattaaga acggattgga ggcacgtgca aaaatgacca agaaacaaaa
    76561 agatcaacaa ctacgaaaag catttgctaa ttttgtagct ggaaatattt ctgaagcaga
    76621 agctcgagct ttagggattg aagctggcaa cggttcagtt actgtcccag aagtaattgc
    76681 atctgaagtt attacttatg ctcaagaaga aaatttactt cgtaaatacg gaacagtggt
    76741 gcgaacatca ggagatgtca aatatccaat tcttgtgaag aaagcagatg cgaatgtaaa
    76801 caagaaagag cgttcaactg atattgctga aacagctatt cagtttgatg aaattttgct
    76861 taatcctgcc gaattcgatg ctttggcaac agtaactaaa aaattattaa aaatgtctgg
    76921 tgttccagtt gaagatattg ttgtggaaga attgaaaaaa gcttatgtgc gtaaagaaat
    76981 caattatatg ttcaatggtg atgacgctgg aaatgaaaat cctggtgcat tagccaaaaa
    77041 ggctgtagca tttaaaaaac ctttagatct aactgcttca ggtgctgggc aaaaattata
    77101 tgatgcatta atcgaattta aaaatacacc agtgacagaa gtgatgaaaa agggacgctt
    77161 tattattaat cgagctgctt tgactgccat tgaaaaaatg aaaacagatg atggatttcc
    77221 tttgttgcgg ccattcacac aagcagaagg tggaattggt taccaattag ttggctatcc
    77281 tgtggattgg acagatgcag cagataaaaa gggtgaacca gacacgccag ttttatattt
    77341 tggcgatttt tctgcattta aaattcaaga agttattggt gccttggaaa ttcaaaaact
    77401 tgttgaaaaa ttctctggta aaaatcaaat tggattccaa atttacaact tgctagatgg
    77461 tcaattggtt tattctccat ttgaaccggc agtatatcgc tacgaaatta caaaaccagt
    77521 tggtggttaa gatggaagag caaactaaag aattgtcttt agaggaaaaa ttcaaatcac
    77581 atattcattt tgaagagggc atggatgatt ctttgctctc tttttattta aatatggcaa
    77641 aagattatgt caaaacagca actggtggcc aacaagaata tcttattttg atggttgccg
    77701 gcattgccta tgaatataga gtttcagagg atgaactcga caaagctatg aatgccatga
    77761 cgccatttat cgtgcaagga gcgattcaaa atgccgaaga gacagactaa taatctcaga
    77821 tggaaagccg aattgctaga catcaaaaca ggaacagacg gaaacgatcg tccaactaca
    77881 atttacgaat ttaagcgtct aatattctat gaagaactcg gtgtgacttc tcaagaaaaa
    77941 tatttatcac agcaagccaa gacagacgtt gtcagacgaa ttaaagtcag atgggataaa
    78001 tccatcacag agaaattaag tgcgctcaaa attgattctg taacgtataa cattactcgc
    78061 atttatacga atcccgatgc aagagaaatg gagttgagtt tagcttatgt cgattagctt
    78121 tgatgaattg aaaacagcgc tgaaatcaac aaagttagca gtgttcagag acaaagccag
    78181 attagggacg atgtatccat acattgtgta ctcaaatgtg agtaacagca aaaaaatggc
    78241 atccggtaaa gtctataaaa aattacctta ttaccaagtc tcttttttta cacttggaac
    78301 agaacaggat ttagttgtta ttgaacaagc gctgcaaaat gctggcattc catattcaga
    78361 ttttacaggt atacaaggtg atgagaacga cgataccgta accaactatt acacatatgt
    78421 gaggtgtgtg gaaaatgcca agtaataaga atggtttttc tgaaatatcg gattatttag
    78481 gaaacctttc aaaagttgat ccgaaaaaat tatcgttgga atctttagaa gaagcagcta
    78541 acttttatct aaagcagttg cttcctaata ttcctaagtc gctcttaaaa aagaaacata
    78601 tgcgcgatca aataaaagta gtagttgaaa acgatcaagt gaaagttcaa tttgaagaga
    78661 cggcctttta ctggcgcttt gccgaaaatg gcacaacaaa tcaacgtgcc caacattttg
    78721 caagtggtac gtatgaacaa aacaaagaaa aaattgaaga aattatgact agaaaaatac
    78781 ttgatttatg ggaagggtga ttttaattgg gaaaacaaga tactttttat tttgaaggat
    78841 tggacgacat tttaattgcg atgatggcaa cgccagattc tgttggaact gcaccgactt
    78901 atagtgaagt tttacgattg ccaattgcca caaaaatcgg tgtcaaaggg aatggaacag
    78961 cattagaaaa atgggcatcc agcaaaatgt ttcgtcgtgt gtcgcgagaa acaaaacatg
    79021 aacttgcgtt ggatcacgtg ggtattccga tagaagtgat ggatgaaatc aaaggattag
    79081 ttgctaaaag cggagtaacg tttagcaaaa ataccgcacg agaatttccg tacttcgcct
    79141 ttggatttat tggaaatatt gaaaatggcg gtaaaaaagc agtttggtat cctaatacac
    79201 aactatccaa tgtgattgac gaagagtatg ccactgcaga ggaagaaaca aaaattgacg
    79261 atgtaactgc aaatctggtt tccatcggac tgaaatacaa taatgtgatg tatgcaagtt
    79321 ttgattcaaa tagagacgga gcttctctag aattatttaa taaattcatt gctcaacctg
    79381 tatacgatga agaacagtgg aaaacattgg ctaaagttgg aggtgcgggt taatggctcg
    79441 gttatctgat tatggaattc acgttgaaga cttaaaaaat tctgctgttg taattattca
    79501 aggcgcagaa ttccctattt catttactat gcaaacgatg gaatttatag cagatgtgta
    79561 tggtggagat tattcgcaat ttgaatctga tatgaacgcc atgctatcta aaaaagaagg
    79621 acaaatttct tctgctaact tatcgcctag tgatctaaaa atcatgcgtg ccttgattta
    79681 tgccatgctg cgtactggtg gtttagagga agatccagaa actattttca aatttttggg
    79741 aatgagtgga gaggtgttgt ctgcttatag tacctgtatg gaaatttttg ctagccagac
    79801 atttcaggtg gaagacctaa aaaaatccaa gaagccacaa gactttcaaa aagcgcaagc
    79861 aaaaagaaag aaaaacaaaa agaatcggaa gagataggaa ctccttggag tttttatatt
    79921 tacgttgctc tcactctatt gaattggagt gagagtttct ttttaaagtc tacacctaac
    79981 ttgtggctca aatcttattt acagtggtta caacaaaaca ccgattttga accacctcaa
    80041 tctgtaacta tggataaatc gccttggtgg tagaaaggag cgctaagata aatggctggt
    80101 aaagaatctg atgtcgttct taattttaaa acgaatggcg aagtcagtta ttcgaaaaca
    80161 atcaaagaaa tcaacaaaga aatgaactta gccgctgccg agtacaaaaa ccaagtgtct
    80221 gcgatggaca aggatgcaac tcaaacagaa aaattgcgag cggctaaaca aaaattagaa
    80281 aaacaattag gattggctga acaacgatct caaatgctga gagaggaata tgaaaaatct
    80341 gtcaaagaaa ccggtgaata ttctgctgaa tcagaaaaac tttataaaca attactcaat
    80401 tctgaaaccg gagaaaataa acttcgtaca gcattagaac agacgaacga tgcacttaaa
    80461 gaacaaggtg acgtttctgt tgatacagca aaaaaactcc agaaaatcga agaaacaggt
    80521 gagaaagtaa aaggcgttgg tgaaaaaatg tctgttggag taaccgcgcc tattgtagcg
    80581 gcaggagcag caggacttgc agcatttggt gaagttgacg aggcacttga taccatcatt
    80641 acaaaaaccg gagcaacagg tgatcaagct gatagacttt cacagtcttt caaaaacgtt
    80701 ggttcaaata ctcatttacc tttacaaacg gttggggaag ctattggtga ggtaaataca
    80761 caatttggat tcatggataa aaaactggaa gattcaacca attatctcct acagtacgct
    80821 gaaatcaatg atacagatgt ttcgcaatca gcaatatctg ctcgacaagc tattgatgct
    80881 tatggactag aatatgatga tttgaattct gtccttgatg taacaacgaa aacatcgcag
    80941 aatactggtc aatctgtaga cgacttgatg caaaaagcaa ttgatggcgc accacaaatt
    81001 aaacaattag ggttgagctt tggtgaaggg gtcactttac ttggacaatt tgagcaatct
    81061 ggtgttgatt caagcgcagc tttaagtagt ttatctaaag caacagtggc ttatgcgaaa
    81121 gacggaaaat ctttaagtca aggactagaa gaactacaag acaaggtaaa aaatgcaggt
    81181 tctgaaacag aagccatcaa tgcagcagca gaagtattcg ggactaaagg cggtcctaga
    81241 atggccgatg caattcgtag aggtactttg aacctggaag atttagcaaa aactgctgga
    81301 gaaagtgggg gagctgtagg agacacattc gatgctactc tcgacccaat tgatcaagcc
    81361 gatcaagcta tgaacaatgc aaaattagca atggctgacg taggtgaagc agtccaagta
    81421 agccttttgc ctttttttga aaaagcaact tccttattac aggaattctc taaatggtgg
    81481 gggtctctag atcaagatac aaagaattgg atcataacaa ttgctggtat agcggcagca
    81541 gttggaccag tactaatcgt tcttggttca cttatgggat ctgttacaaa aatcgttggg
    81601 gaagttaaaa gttttatagg agtttggcaa ggacttgctg gtttatttgg aatgtcggga
    81661 ggctggtttg cattagcagt tatagctatt ggcgcattag ttactggact aatttgggca
    81721 tataataacg ttaaatggtt tcatgatgga gtgaattctt tcttcaaagg tgtttcagat
    81781 gtagctgttg aaatatttaa ttttttaagt ggttattttg gtggattttt cgatggtgtt
    81841 atagcaaatt tcaataattt ttataatgct ggaaaacgaa ttttcagtgg ttttctagat
    81901 tttatcactg gagtatttac agggaattgg tcaaaagcat ggcaaggtct agttgatatt
    81961 tttggaggta ttttcgatgg tattgttgct gtagggaaag ctcctattaa tgccatgatt
    82021 ggattgatca atggatttat tggtggattg aataatataa agataccaaa atgggttcct
    82081 ggtgtaggtg gaaaatcatt ttctatttca aaactgcctt atttagcaca aggcggtcat
    82141 ctaatcaatg gacaagcgat tgttggtgaa gctggacctg agttactgac tgccaagaat
    82201 ggtaaaacca cagttactcc attatcagac gaagaaaaac gcaaagggat cagtggaaga
    82261 gtttctggag gtagcattga acagcatata cacattggca aagtcgatgc aaacaatcca
    82321 tctgagttag atcgtatgaa tcgtaaattt gctaaagcaa acaaacaggc tattcgtgat
    82381 ttgggaggtg ttcctatttg agtcgacaat ttatgaatcc agatgaacca aattttattt
    82441 ggaaaaatcg gaatgcagta attgatatga attgcatcat tgaggcagag cttccagata
    82501 ttatgccgaa caagcgatac gaaacttaca cgattcaggg ccgaagcgga gaattgacgg
    82561 agacgtttga tgactatgaa ccttttgatt tggaaataga agggatcact attccacatt
    82621 cgaaactgag agaagtcaaa cgatggctca ctggtaaaag ccaattaatc acacataatg
    82681 atccagacaa gtatctagag gctatctgca gcatggataa agaagtccct ttcgaaaacg
    82741 agtggggctt cttttataca ttcgatgtta cttttcgttg tcagccactc aaaagaaaaa
    82801 tcggtgaagc acctaaaatt tttcattcta gtgttatgga tatttttgat catggtgacg
    82861 aaattgcaca tccctatctg gaaatagaat cgaacggagg agatataacg atcgctgtcg
    82921 gtgataaaag cctaacaata cttaatacgt tagctgcaac aatcgtggtt gatactcagc
    82981 ttggaaaagc aatacaagaa ggtttgaatt tatttacgcg tggtgattgg ccagtattgc
    83041 agcctgaatg gaatcaggta aaaatatccg gaaaatttaa agaagtgcgg ttttggaata
    83101 ggagtgtgta tctgtgacgc aagaatttat ttatgcttat aaaaaaatgc cagatgattt
    83161 gagcgtgaac ggagcgtcgt tagttgattg ggaagatttg ccagaaatca atcgtgtgct
    83221 gaatggccaa tatcgttttt atggtaacta ttcaagaagc ggacagtatc gctcttattt
    83281 aaaaaaagga aattttataa aagcgaaggt accagatgga tcatggcaat attttgaaat
    83341 ttataatgtc aaaaagaatt tgacctccgt ttctgtaaca gctcggcata ttggttttat
    83401 ggccaataag aactttattg tcaagtcgtt tacggataac ggcaatgggt ctcagatcat
    83461 gaccaatctt aaaaacagtt tggcatttga tcaaaaattt aactatcttt cgaatgtagg
    83521 gacaacgcac caatttacag caagacaagt cgcgccagtt gaagcaatca ttggttcaaa
    83581 taacggtaat caaaatttga ctggcgtgac tagcgcggaa cttgatatgg ataactatga
    83641 tttgaaactg gtaaaacaga ttggatcaga taatggtttt cggattgatt ttggcatcaa
    83701 tttagaagca atcgaagaag aaattgatga agaatcaatt gtcaatagtt tgtatttggt
    83761 tggcggtgtt cctgataacg attatgatga agacaaagaa cctatcgaat atggttattt
    83821 agaaattgat ggagtaacca acgagaatcg acgtattgcc aaacgtgaaa acggagattg
    83881 taaaacagtt gatgaattga tcaaatgggg caaaacctta tttgacaatg atcgtatcca
    83941 tgagccaaaa gctactcata cagtcagtat ggtggcgttg gaacacacac tcgaatacgg
    84001 tgacatgtat caagagctag cgtctttaca ctttggtgat gtcgctcatg ttagggcgaa
    84061 agagctagat atcgagataa aagagcgtat ggtcgaatac acttatttcc caacgcttgg
    84121 gaaatataag gatattgttt taggtaatga tttatcactg tacacttcgg cagtaaatac
    84181 tcaagcacaa gaattgaaaa agaaaatcga caatcgaaca gaaacgttag ttcaaaatgt
    84241 gttgaatgcg acggcatgga tcactggtaa ttctggtggg catgtcgttt ttcgtccaga
    84301 aaaagctcca tcagagattc ttatcatgga tactccaaat gtggcgaatg caaagcgagt
    84361 gtggcgttgg aatttaaatg gcttaggtta ttcagacaac ggagtaaatg gcccgttcgg
    84421 tattgctatc acatcaaaag gagaaattgt tgctgacttc atcaaagtag gaacaataaa
    84481 tgcagaagta ttcgaaactt cctttaatgc ttatggtgat gtgttaaaac ttgtaaaagg
    84541 cacgcttcaa atttggaatg aaaacaaaaa aatcatggag ctaaccaaaa aaggtatgga
    84601 attctggaat agaaaagaat ccattggaac gatcggaaca acagattcag caggaaatcc
    84661 atttccaaat gctgtaacac ctacacctct tgaggaaaat tctttggtaa tacgtacaaa
    84721 tggcgatgga aaatacattt taatttctcc aactgcagaa aaaggatttg tgttattagg
    84781 aaacggaaaa gcatattatt tcggtgattt agatattcag ggaaaactta ctgttagagg
    84841 taaagaagtg ataccaggac aaaatggcgg tccatctggc ggaggagaaa cacctggtgg
    84901 gtatcctgat gaattaaaaa cagatgcaga aaagagagct tggagaat
//
LOCUS       DAFLVO010000003        81384 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.003, whole genome shotgun sequence.
ACCESSION   DAFLVO010000003 DAFLVO010000000
VERSION     DAFLVO010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 81384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81384
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.003"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(79..366)
                     /locus_tag="L1U99_000211"
     CDS             complement(79..366)
                     /locus_tag="L1U99_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210787.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            500..1168
                     /locus_tag="L1U99_000212"
     CDS             500..1168
                     /locus_tag="L1U99_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1210788.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            complement(1459..2199)
                     /locus_tag="L1U99_000213"
     CDS             complement(1459..2199)
                     /locus_tag="L1U99_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210789.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(2329..3276)
                     /locus_tag="L1U99_000214"
     CDS             complement(2329..3276)
                     /locus_tag="L1U99_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1210790.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(3405..4169)
                     /locus_tag="L1U99_000215"
     CDS             complement(3405..4169)
                     /locus_tag="L1U99_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBN1210791.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIQLMEEASTFLAKNLIKKYK"
     gene            complement(4173..4562)
                     /locus_tag="L1U99_000216"
     CDS             complement(4173..4562)
                     /locus_tag="L1U99_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210792.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            4697..5239
                     /locus_tag="L1U99_000217"
     CDS             4697..5239
                     /locus_tag="L1U99_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HBN1210793.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            5387..6019
                     /locus_tag="L1U99_000218"
     CDS             5387..6019
                     /locus_tag="L1U99_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210794.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(6153..6278)
                     /locus_tag="L1U99_000219"
     CDS             complement(6153..6278)
                     /locus_tag="L1U99_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1210795.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(6412..7305)
                     /locus_tag="L1U99_000220"
     CDS             complement(6412..7305)
                     /locus_tag="L1U99_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HBN1210796.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(7487..8413)
                     /locus_tag="L1U99_000221"
     CDS             complement(7487..8413)
                     /locus_tag="L1U99_000221"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HBN1210797.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(8498..9259)
                     /gene="pflA"
                     /locus_tag="L1U99_000222"
     CDS             complement(8498..9259)
                     /gene="pflA"
                     /locus_tag="L1U99_000222"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBN1210798.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(9503..11734)
                     /gene="pflB"
                     /locus_tag="L1U99_000223"
     CDS             complement(9503..11734)
                     /gene="pflB"
                     /locus_tag="L1U99_000223"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBN1210799.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(12011..14461)
                     /gene="parC"
                     /locus_tag="L1U99_000224"
     CDS             complement(12011..14461)
                     /gene="parC"
                     /locus_tag="L1U99_000224"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HBN1210800.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(14473..16518)
                     /gene="parE"
                     /locus_tag="L1U99_000225"
     CDS             complement(14473..16518)
                     /gene="parE"
                     /locus_tag="L1U99_000225"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HBN1210801.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(16684..17118)
                     /locus_tag="L1U99_000226"
     CDS             complement(16684..17118)
                     /locus_tag="L1U99_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBN1210802.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            17245..17883
                     /gene="plsY"
                     /locus_tag="L1U99_000227"
     CDS             17245..17883
                     /gene="plsY"
                     /locus_tag="L1U99_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBN1210803.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(18015..18890)
                     /locus_tag="L1U99_000228"
     CDS             complement(18015..18890)
                     /locus_tag="L1U99_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBN1210804.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(18972..19763)
                     /gene="codY"
                     /locus_tag="L1U99_000229"
     CDS             complement(18972..19763)
                     /gene="codY"
                     /locus_tag="L1U99_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBN1210805.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(19781..21181)
                     /gene="hslU"
                     /locus_tag="L1U99_000230"
     CDS             complement(19781..21181)
                     /gene="hslU"
                     /locus_tag="L1U99_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HBN1210806.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(21195..21743)
                     /gene="hslV"
                     /locus_tag="L1U99_000231"
     CDS             complement(21195..21743)
                     /gene="hslV"
                     /locus_tag="L1U99_000231"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HBN1210807.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(21780..22685)
                     /gene="xerC"
                     /locus_tag="L1U99_000232"
     CDS             complement(21780..22685)
                     /gene="xerC"
                     /locus_tag="L1U99_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HBN1210808.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(22883..24259)
                     /gene="trmFO"
                     /locus_tag="L1U99_000233"
     CDS             complement(22883..24259)
                     /gene="trmFO"
                     /locus_tag="L1U99_000233"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HBN1210809.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(24228..26306)
                     /gene="topA"
                     /locus_tag="L1U99_000234"
     CDS             complement(24228..26306)
                     /gene="topA"
                     /locus_tag="L1U99_000234"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBN1210810.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(26428..27285)
                     /gene="dprA"
                     /locus_tag="L1U99_000235"
     CDS             complement(26428..27285)
                     /gene="dprA"
                     /locus_tag="L1U99_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBN1210811.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(27341..28108)
                     /locus_tag="L1U99_000236"
     CDS             complement(27341..28108)
                     /locus_tag="L1U99_000236"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBN1210812.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(28101..28961)
                     /gene="ylqF"
                     /locus_tag="L1U99_000237"
     CDS             complement(28101..28961)
                     /gene="ylqF"
                     /locus_tag="L1U99_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBN1210813.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            29221..29619
                     /locus_tag="L1U99_000238"
     CDS             29221..29619
                     /locus_tag="L1U99_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1210814.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            29898..30398
                     /locus_tag="L1U99_000239"
     CDS             29898..30398
                     /locus_tag="L1U99_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBN1210815.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(30481..31032)
                     /gene="lepB"
                     /locus_tag="L1U99_000240"
     CDS             complement(30481..31032)
                     /gene="lepB"
                     /locus_tag="L1U99_000240"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBN1210816.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(31184..31411)
                     /locus_tag="L1U99_000241"
     CDS             complement(31184..31411)
                     /locus_tag="L1U99_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HBN1210817.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(31408..31926)
                     /gene="msrA"
                     /locus_tag="L1U99_000242"
     CDS             complement(31408..31926)
                     /gene="msrA"
                     /locus_tag="L1U99_000242"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBN1210818.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(31946..32659)
                     /locus_tag="L1U99_000243"
     CDS             complement(31946..32659)
                     /locus_tag="L1U99_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HBN1210819.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(32662..33558)
                     /locus_tag="L1U99_000244"
     CDS             complement(32662..33558)
                     /locus_tag="L1U99_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBN1210820.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(33716..34558)
                     /locus_tag="L1U99_000245"
     CDS             complement(33716..34558)
                     /locus_tag="L1U99_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBN1210821.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            34690..35343
                     /locus_tag="L1U99_000246"
     CDS             34690..35343
                     /locus_tag="L1U99_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBN1210822.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(35406..35933)
                     /locus_tag="L1U99_000247"
     CDS             complement(35406..35933)
                     /locus_tag="L1U99_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBN1210823.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(35953..36900)
                     /locus_tag="L1U99_000248"
     CDS             complement(35953..36900)
                     /locus_tag="L1U99_000248"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBN1210824.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(36912..38798)
                     /locus_tag="L1U99_000249"
     CDS             complement(36912..38798)
                     /locus_tag="L1U99_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBN1210825.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(38958..41036)
                     /locus_tag="L1U99_000250"
     CDS             complement(38958..41036)
                     /locus_tag="L1U99_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBN1210826.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(41049..41324)
                     /locus_tag="L1U99_000251"
     CDS             complement(41049..41324)
                     /locus_tag="L1U99_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210827.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(41686..42141)
                     /locus_tag="L1U99_000252"
     CDS             complement(41686..42141)
                     /locus_tag="L1U99_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210828.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(42295..43503)
                     /locus_tag="L1U99_000253"
     CDS             complement(42295..43503)
                     /locus_tag="L1U99_000253"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBN1210829.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(43615..43947)
                     /locus_tag="L1U99_000254"
     CDS             complement(43615..43947)
                     /locus_tag="L1U99_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBN1210830.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            44095..44970
                     /locus_tag="L1U99_000255"
     CDS             44095..44970
                     /locus_tag="L1U99_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1210831.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(45052..45633)
                     /locus_tag="L1U99_000256"
     CDS             complement(45052..45633)
                     /locus_tag="L1U99_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HBN1210832.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(45639..46898)
                     /locus_tag="L1U99_000257"
     CDS             complement(45639..46898)
                     /locus_tag="L1U99_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBN1210833.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(46900..47946)
                     /locus_tag="L1U99_000258"
     CDS             complement(46900..47946)
                     /locus_tag="L1U99_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210834.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(48181..48456)
                     /locus_tag="L1U99_000259"
     CDS             complement(48181..48456)
                     /locus_tag="L1U99_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBN1210835.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(48699..50009)
                     /gene="der"
                     /locus_tag="L1U99_000260"
     CDS             complement(48699..50009)
                     /gene="der"
                     /locus_tag="L1U99_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBN1210836.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(50191..51420)
                     /gene="rpsA"
                     /locus_tag="L1U99_000261"
     CDS             complement(50191..51420)
                     /gene="rpsA"
                     /locus_tag="L1U99_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HBN1210837.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(51555..52235)
                     /locus_tag="L1U99_000262"
     CDS             complement(51555..52235)
                     /locus_tag="L1U99_000262"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBN1210838.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(52284..52919)
                     /locus_tag="L1U99_000263"
     CDS             complement(52284..52919)
                     /locus_tag="L1U99_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBN1210839.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(52985..54388)
                     /locus_tag="L1U99_000264"
     CDS             complement(52985..54388)
                     /locus_tag="L1U99_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HBN1210840.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(54375..55406)
                     /locus_tag="L1U99_000265"
     CDS             complement(54375..55406)
                     /locus_tag="L1U99_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1210841.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            55437..55658
                     /locus_tag="L1U99_000266"
     CDS             55437..55658
                     /locus_tag="L1U99_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBN1210842.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(55823..56560)
                     /locus_tag="L1U99_000267"
     CDS             complement(55823..56560)
                     /locus_tag="L1U99_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HBN1210843.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(56713..58053)
                     /locus_tag="L1U99_000268"
     CDS             complement(56713..58053)
                     /locus_tag="L1U99_000268"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBN1210844.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(58290..59813)
                     /locus_tag="L1U99_000269"
     CDS             complement(58290..59813)
                     /locus_tag="L1U99_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBN1210845.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(60191..60802)
                     /locus_tag="L1U99_000270"
     CDS             complement(60191..60802)
                     /locus_tag="L1U99_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBN1210846.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(60925..61050)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(61132..61848)
                     /locus_tag="L1U99_000271"
     CDS             complement(61132..61848)
                     /locus_tag="L1U99_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBN1210847.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(61854..62423)
                     /gene="scpB"
                     /locus_tag="L1U99_000272"
     CDS             complement(61854..62423)
                     /gene="scpB"
                     /locus_tag="L1U99_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBN1210848.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(62407..63204)
                     /locus_tag="L1U99_000273"
     CDS             complement(62407..63204)
                     /locus_tag="L1U99_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBN1210849.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(63174..63545)
                     /locus_tag="L1U99_000274"
     CDS             complement(63174..63545)
                     /locus_tag="L1U99_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBN1210850.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(63564..64451)
                     /gene="xerD"
                     /locus_tag="L1U99_000275"
     CDS             complement(63564..64451)
                     /gene="xerD"
                     /locus_tag="L1U99_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HBN1210851.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(64547..65020)
                     /locus_tag="L1U99_000276"
     CDS             complement(64547..65020)
                     /locus_tag="L1U99_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBN1210852.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(65125..65988)
                     /locus_tag="L1U99_000277"
     CDS             complement(65125..65988)
                     /locus_tag="L1U99_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBN1210853.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(66184..68283)
                     /locus_tag="L1U99_000278"
     CDS             complement(66184..68283)
                     /locus_tag="L1U99_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBN1210854.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(68503..69612)
                     /gene="rpoD"
                     /locus_tag="L1U99_000279"
     CDS             complement(68503..69612)
                     /gene="rpoD"
                     /locus_tag="L1U99_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBN1210855.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(69636..71477)
                     /locus_tag="L1U99_000280"
     CDS             complement(69636..71477)
                     /locus_tag="L1U99_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBN1210856.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(71659..73974)
                     /locus_tag="L1U99_000281"
     CDS             complement(71659..73974)
                     /locus_tag="L1U99_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBN1210857.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(74159..75019)
                     /locus_tag="L1U99_000282"
     CDS             complement(74159..75019)
                     /locus_tag="L1U99_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HBN1210858.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(75078..75599)
                     /locus_tag="L1U99_000283"
     CDS             complement(75078..75599)
                     /locus_tag="L1U99_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBN1210859.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            75877..76638
                     /locus_tag="L1U99_000284"
     CDS             75877..76638
                     /locus_tag="L1U99_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1210860.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            76664..79255
                     /gene="mprF"
                     /locus_tag="L1U99_000285"
     CDS             76664..79255
                     /gene="mprF"
                     /locus_tag="L1U99_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBN1210861.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(79443..80630)
                     /gene="tuf"
                     /locus_tag="L1U99_000286"
     CDS             complement(79443..80630)
                     /gene="tuf"
                     /locus_tag="L1U99_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBN1210862.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            80998..81354
                     /locus_tag="L1U99_000287"
     CDS             80998..81354
                     /locus_tag="L1U99_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBN1210863.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
BASE COUNT        22339 a        17051 c        13943 g        28051 t
ORIGIN      
        1 gtatcatgac acttttttgc caaaaatgta aaaaatggtt gttttgacat cataaacgtc
       61 ttgttttctt atttttactt atatcaccac tttattttct atctctttca ctccataaag
      121 aggaatgagt tcttcttttg actgataata aacagctttc tcacggttct tcatcaaaaa
      181 aagaaagatg tctttcatag caagtggtgc tttgccgtgt tcaaataaaa agataaattg
      241 atttgcttta tttatctgga ccattgtcac aggcaccagt ttttgttctt gagccaaaaa
      301 aactccttga tactctgttt ttttgggtga ttttgtaaga attgtcaata agtctgctgc
      361 tcgcattttt ccactcctta tttgataaat aaaaagaaac agccaaaaat aatttttttt
      421 cattttcctc ttgaagtaag agtataagtc agtataataa agaagttgct gaaaattttc
      481 aaaagaaaag aggctagaaa tgaaaaaatt aaatttattt acagaattgt gcggaatcat
      541 tttaggcgca ggaatctacg gattagctgt gacaggaatc aatattccat ctaagctggc
      601 agatggtggg gttactggta ttgctttgct tttgcataat ctttttggat tcgctccttc
      661 tgtcacttca ctgcttttta atttaccttt attgcttatc tcattgtttc tttttggaaa
      721 acacgctttt ctccggacga tcgtcggaac atttgcgcta gttttctttt tacatttatg
      781 ggagagcctt catatacatt ttgctgtaga tagtctactg atcaatagtt tgatgacagg
      841 tattctttct ggcattggtt gcggtctcgt ctttcgattc ggcggaagca caggcggaac
      901 agatatcatt tatcaagcca ttgaaaaata ttttcatatt aagattggca aaagtctttt
      961 cttgattact tttggtattt tagttgtctc cttgctttat ttggatctca cacattttct
     1021 gtatacatta cttagctgtt ctattctatc ttatacattg aataaagtga agtatctgga
     1081 aattggatct gttttgcccc aattggaagc aaaacagact acagaaacat ttgaaccact
     1141 tgatcctctt gaacagttag agcactgatt cttatttttc actactttat ttaatttaca
     1201 gaaatatcat tatgtaaact aaaatgatat tattcagtaa aatcttcttt ataaaaaaat
     1261 aaactatttt tgcaaacgat ctgcgaaaat agtttgtttt tttattttgc cattattttc
     1321 ttacttattg ggagaaaaaa ttcgcttaaa ctcaaaaaaa tttgaggata cgatataaac
     1381 tttcggatag agtataaaat aaggaaacgc cgcagcgttt cctttccaac tgtagccgaa
     1441 tataaatttg tatatcactt atttaaaata gctattttct cccaaagagt ttccttgatc
     1501 atcgatcaat ccttgtaatg agcgttctaa gataccatgg ctttttttcg attttttttc
     1561 ttctgactgc tttgtttcct ctaacgtttt tgttcgattg aatgttcgta cagacggctc
     1621 accatttctt ttttcttgat acggcgtcgg ttctgtatcg aacaacagat aagagtcatc
     1681 cgtttttttc atcgattcga ttaaatgatc ctcagaaatt ttgctttctc tagggtctgg
     1741 gataatcgat gcgggtacat atttaggaac aaaataagaa cgctcccgca ccttcgtgtc
     1801 aacagatgcg tttcgtgtag tatgcttgga ctctgtcctt gtttcacttt gtctgacaga
     1861 acgagaggaa tcaccaaaaa gtttttttcg tcctgtcgat gtgatttctg attggtaatg
     1921 gccggtataa tccggtaatt ttcctttatg cttttccaaa ttttccttac gcggagctga
     1981 cttcaatcca tttgttgcac gacgcttgcg acggattttc tcggtgttcg tgttcgtgaa
     2041 atgaaattct ttcatctgtt caaacgggga ctgattctgt tcagtcaaaa gatcttcttg
     2101 tccgtcaaat aatactcgct tcttgtcgtt ggttaatttt acgcctaact catcatcgta
     2161 cgcaggaaaa cggaaatgtt ttcgtctgat ttctttcatt caaaccatcc ttctcaaaaa
     2221 tggaactttt ctcaataata gcacagattc attgttttca gtagcaatgc gctgattatt
     2281 ttaagaaaat agcgatgaat ttcataaata tatatatagt aataagactt aattcgttgt
     2341 ctctctgata actagttcag gaaaaaaacg acgataacct tgactcgccc ctttttcttc
     2401 tatttttttt aacaacattt ctccacatac ttcacccata cgtataatat cttgcttgat
     2461 cgttgtcaat ttaggtgaac tgatttggtc taaaaatacc ccatcaaatc caatcacacc
     2521 aaattcttcg ggcaagtgtc ctccagcatt tataatccct cttactgctc ctagtgctag
     2581 ccgatctgaa ctacatacaa aacaagtttt atctgtaaaa tctgcccagt tttctgtcat
     2641 atatctttct acttctgtcg aatgatttgg aaaccgcaag attttactag gaagatcaac
     2701 ttccttcatc acagataaat aaccagtttc ccttgaaatt tcaaaaggct cgtccacttc
     2761 gataccgata taaataatcg tttgataatc tctttctaag gcatattgcg ttgcttttgc
     2821 tgtaccatat tcattatcgc tgtctacata atcatatcct tcagaatttt ccccaaacaa
     2881 gacaactggt ttttccaaac ggtcgatcca atcgaagtct ttttttctga cacctgtgat
     2941 gatgtatcca tcacaagaac cgacgtcgaa ggcatcattt gtaactaatt ggagagaata
     3001 atgcgcttta ccgatccgtt tagcgattcc catcagcaaa ttcatgtaat agggctcagt
     3061 tgtgtcgatt tcttccagta taaataattt gatgatctgc gaccgattcg tgacaagtgc
     3121 ttttgcagca atatttggac ggtaatccag ttcagccatt gctgagaaaa ctaactcttt
     3181 caattcgtca gtcacctgtt ccggatgatt gatgactcga gagaccgtca tttttgaaac
     3241 attggcacgt tttgcaacat ctgctaaagt gggcatgctc tcttcctttc taacatgttg
     3301 tcattcttac tatcaattat accaaatttt cctaacagag tttattatag cccaaaataa
     3361 aaaacggaaa atcctctatc gtcatgagtg attttccgtt tcaattattt atactttttt
     3421 atcaaatttt ttgctaaaaa agtggaagct tcttccatta gttgtatttg taccatatgt
     3481 cgctgtgttt ttgaggaacg aaaaacaatt tcttttccgt aagacttatg ccgatttttt
     3541 tctacaaatc gttccgtttg tatataaggg attttttcgt cagcttgtcc atgccaaaag
     3601 aacagaggac gtccagctaa cttttccggc tgcaatgaca aatcatagct cttaacccat
     3661 gaaatcaaat caaaatagtc ttttggtacg acataattat attccgatgc gcgccttacg
     3721 atttcttttc catattccaa aggtgcaggg gaacccatca aacacacgcc cgctactata
     3781 tgaggatgtt tagccaacaa ggcgcatgtt gtcattcccc ccatcgaaac cccgccaact
     3841 gcaagctgat catgtagaag acctcttttt tctaaatgct tgataagtgt gtcaaattca
     3901 aacagatttc cgtagatact atcccaaaat gtataggatg gaatagaaga aaccggctgt
     3961 ttgcgctccc catgattcat cgcatctggc aggatcacac gaatgccctg ctgcgcaatt
     4021 tttcttcctt gcgtcaaaac taactcctta cttgtctgcc atccgtgata atagatgaca
     4081 acgggaatac gttcctctct taattctttc agaacaactt ctaacactgg aatatgatgg
     4141 acagaacgtt tcaatataat tggattcaat tgttactcac ctattttcat taaatttcct
     4201 gatcgccata gcaaccatgc tccaacagtt gtctggaaca ggttcagtgt accaaataat
     4261 ataaatgcag gactgaatgg ctcgggaaat aagcacagag aacaaagtcc caccactcct
     4321 aatgctagcg aaaggagtgg ataaatagaa aaattcaaaa aactggcaac gctaccgaaa
     4381 atattaccaa taaacagtat caaaaagaaa aaaacgctta aaattaaacc atctgtcagc
     4441 gacatctgaa aaacaatgtt ctctacctca attggctgtt gaatcgaata gacacctaag
     4501 tatatactga gaaggagact tagcacgtgg ctggcacaaa acacacgatt gaccgttttc
     4561 attttaatca cctaacctat ctttataatt ctattataat cattttatca tttttttgta
     4621 tgtataaagt ttcaattttt cttcacttac gatttttttt gatattgttg ttatataaat
     4681 gaaaggagtt ttacaaatga ttgatccaaa aatgttgggg atgatcttcc tcattaattt
     4741 tgcttatatc actctgaaca cgttacgttt catgttgaca atgaaaggct atcgactgat
     4801 tgctccactt gtcagtatgg tcgagatcac gatttatatc gtcggcttat cccttgtttt
     4861 agatcgttta gataatccac tgaatttatt tgtctatgcg ttaggttacg cagtaggtat
     4921 cagtgtcgga attttgattg aagacaaatt ggcattagga tacatcatgg tcacaacgat
     4981 tttgccagca aatagcgcag aagataaaag tttgccgggt atactgagag aacacggtta
     5041 tggtgtgaca cagacttctg caatggggct ggaaggtgag cggctagttc tcgaaatact
     5101 ttctcctaga aaaagcgaac gtgaactgta tcgcctgatc aaagaaatcg aagagcgtgc
     5161 ttttatcatt tcttatgagc caaaatatat ttcaggtggt ttctggacta aaaaagtgag
     5221 aaaacgacaa ggaaaataac tcacaaactt aaaaactgtc taatatctaa attaaatttt
     5281 aaatgttaga cagtttttat ttattatttt gattaaaaaa catcgacata tactcatcaa
     5341 tttgttatta tactttatat acttatcaat ttaatttgga gatattatgg aaattcaacg
     5401 tagaaccact aattttttac atttaggctc tttttttgca actttgacga tcttattttt
     5461 tctatgttat tcatacctta agacctcaca tgcgccttct agtgcattag gctggttgct
     5521 tttggatcat tctgatatca cagaagccga agaaaatccg ttttttttga ttttgtcttc
     5581 tctttgcggc ttactgtttt ctgtttattt cggtgcctat ttttttcatc gacatcctgg
     5641 tacgttaaac gaagcttcaa gcgtattgat tgcatttaaa acgttttctt ttttagcaat
     5701 tcttttttat tcgtttaatc acaatacgct tttcttcttt atcatgaatg gtttagtcgt
     5761 gattttatcc atttttactt attttatttt ttcactcatt tttagccaat tgaaatgtcc
     5821 gctcttcttt cgattagttc ctgtcacctg ttttatttac agcttgtttt ccttttttgt
     5881 ccttgcttta atgccactga ccaacccttc gacgatccaa gtcgcaggaa atctgttgga
     5941 tatgctcttc atcgtcagtc taggtgtatt tatgtggcaa agaaaaaaca aacaaaataa
     6001 aaagcatttt gaagcctgac tattacgact tcataaatgc ttttttagtt ttaaacactt
     6061 caatctaaaa gaataaccca agattggata aattattaat gactcgccat tcgtttctta
     6121 gtgattctgg attatcaaat ggacttccta atctaatcag ctagttcttc ccataaaatg
     6181 ccatacttga ctgaatcata atattgatta tttaaaaatc taacttttct tatcactact
     6241 tcctttgtca ttccacattt ctcaccattt ttttgcattc ctttgtttcc agaccatgta
     6301 gtgaatctaa taggtggtag ataggcaaaa tactcaaata attcttttaa ccataaagga
     6361 agagaaaggc tcctcctgca agagtcagta taatttttgc ttactgctct cttaggtttt
     6421 actcactaaa actgttccat attctttgat ataagaaaat gcatgcggta taaatttctt
     6481 gctcagctca gaaaagattt gtcgtttaag aaaggccatt tcctccattg tcaatgaagg
     6541 atccaatgtt ggtaattcaa tctcaaaatt gtttttttcg acaataggta attctaatgt
     6601 gaatgattct tcttccttta tagtattcgt cacaagtaga gactgatgga aaatactagg
     6661 ccggcgattt ttatatttat tcttacgtat cctgtcaacg ataacttcta tttgatcaaa
     6721 aaagtacgat tcatttacgt ctccaataag ttcggctaat tctttgaatg ccttcgttac
     6781 aggaagctga ttcttctgta caaaaaagta attagccaaa gtaagcggga agtgttctat
     6841 agaggaaagt gtgataaaac ggtacttctc atttcctgca gttgtcctca gcaattctgt
     6901 ctctcggctg tttcttactc cataaaaata cgcttctttc cgttcatctt cgaaacaata
     6961 cgcccaaata acttctccca tcgctaattt ttgttcatca acagagagtc tcttcaattg
     7021 ttcagctatg gtttcagcag ccgaagtggc ttgttgcaag taatctttag gatcaaatat
     7081 tggaaagttc aaatgatatc ttcgttcttc cctcttgatt aatcctgcat cgatcaataa
     7141 atcaagaaaa tgggaaaatt tattttgcga aaattctttt ttcaattctc ttagaatcgt
     7201 ttcttgttct cgatgttcat atagataatc ggtcaatgaa gaaaaaagcg gatcatcggt
     7261 cagtttttga taaaagtttt ccttattttt tgaataatag ttcatatatg ttctcttttc
     7321 tatccgtttt attttactta aaaggctttt acgtaaaaag gaggaagaac aagagtcata
     7381 attgactgtt attctcctcc atttcttcgg cctttagtat gttctatgtt tctttttata
     7441 tcaatcgctt atccattcat tttgaatgct tcatactacc atttgattag ctaaatacag
     7501 ccgtcaattg aggtacgact tgttttttac gtgaaacgac acctttaagc aaagcacggt
     7561 tgttggtcaa agttgtttgg aaagcttctt ctactttttc ttttccttta ccagcaacaa
     7621 gtaattctga atcactgtct aagatgtttg tgacaactaa tacgaacaga tcgtagccat
     7681 ttgctttcat ttcatcttcc attgctgctt ctagctctgc ttgtcgatcc atcacttcat
     7741 taaggtccac tgtattgact tgagcgatac gaacgttgga actgcccatt gggaaacttt
     7801 ttgcatccaa atcaagaaga accgcagctg atttatcact tagatttgtt cctgctttca
     7861 acatttcaag tccataagtg tttagatcga cttcagcgat tgctgcaagt tcttttgcag
     7921 ctgcttcatc ttcaggcgta catgttggtg atttgaacaa caatgtatct gaaatgatag
     7981 ctgagagcat gattcctgcg atttctttag gaattgttac ttggttttct ttatatagtt
     8041 ttaaaataat cgtacttgta catccaactg gttctgcacg atagtacaat ggattagctg
     8101 tttcaaagtt tgcaatacga tggtggtcta ctacagctaa aatatttact tcgctgatat
     8161 ctgaaatact ttgttggaat tcattatgat ccacaagcat gacatctgca ttttctgctt
     8221 tagctgactc tactactcgt ggtgcagata gctgaaagtg gtctaatgcg tattgtgttt
     8281 cttcattagg tgtacctaga gcaactgctt ctgtttcttt acctaattca ttttgcaagt
     8341 gtgaaaacgc aatggctgcc ccgattgcat ctgtatctgg attttggtga ccaaaaacta
     8401 aaatttttga catgtcattc gctcctttgt gatttctcct atttaataat agcaaaaaaa
     8461 cggaaagaag caatacttat cttctttccg atgcgaccta tcgcgttaaa tattttgtat
     8521 actcttctgt atgaagcaat cgtttagcat tttcgacacg ttcttttgta ggtggttcga
     8581 tcccttctaa tggatatttc aaaccaagtg tttcccactt gtattttccc atcgtatgat
     8641 aaggaagaat ctctactctg tctacatttg acaaggtttg aataaagttg tctagtcgga
     8701 tcaaatattc atcataatca cttcgctcag gaactagtac atggcgaatc caaaccggtt
     8761 tgttgatttt tgacaaatat tgagccattt ctaaaatatt ttcattgtcc caatgcgtta
     8821 gttttttatg ctcttcatta tcgatgtgtt tgatgtcaaa taacagtaaa tctgtatact
     8881 tcatcaattc ttgaaaacgt gaaaagaaag gttcttcata cgtaaaaggt tttccgcatg
     8941 tatccaatgt agtatgcatc ttccgctctt ttgctttttt aaatagttcg atcaaaaaat
     9001 cgatctgcaa tagaggttct ccaccactaa cagtaatacc acctttatct ccccagtaag
     9061 gtctgaagcg ttctgcttta tctaaaagtt catctgctgt gtattctttc cctccgccaa
     9121 tattccaagt atctggattg tgacaaaatt ggcaacgcat gcggcatcct tgcataaaca
     9181 cgacaaagcg cagtccaggt ccgtctactg aaccgaaagt ttcgatagaa tgaacatagc
     9241 cgattgtttt ttcttccatt taagttcaca tcttttcttt gatttcattt taagtacaag
     9301 ttagctgtcg aagcgaagct ttctgaacaa aatttttcgc aattgccgct tcgttatgtg
     9361 taaaatttac agggacggaa catacaagtc ctgcccctgt aaatcgtttc tttcaaataa
     9421 gcatactgat tattcgattt tgatgcgatg gctattcaac gtcctttcga cgctaagtcg
     9481 aaaaactttt ttcacgaact ttttacattc tgtcgtgtga agttctcatc aagacatcta
     9541 attgttgttc tcttgtcaag tcacggaatt taactgcata accagatacc cggatcgtca
     9601 agttcggata tttcattgga ttttccattg catcacgcaa taaatcatta ctgaatacat
     9661 tgacattcaa atgataagct ccttttgaga agtatccatc taagacatta cgcaagtttt
     9721 cgattcttgt atcttgttct tttccaagac ctgaaggatt gattgtttgg gtatttgaaa
     9781 ttccatccaa tgcacagccg taattcattt tagctgttga gttcaggcta gctaataacc
     9841 cactttgttc cgcattgtaa cttggatttg ctcctggcgc aagtggtttt ccagcttcac
     9901 ggccatcagg agtatttcct gtatttttac cgtaaacaac atttgaagta atcgtcaata
     9961 atgaagttgt tggttttgag ttgcggtaag ttttatgacg tttgatttgt cccatgaagt
    10021 attccaagat ccatgaaact aattcatctg cacggtcatc atcatttccg tatttaggga
    10081 agtcgccatc cacttcaaaa tcaactgcta ttcctttttc attacggatt gcttttactt
    10141 ttgcatattt gatcgctgac aagctgtctg ccgcatgaga gatcccagca atacctgtag
    10201 caaatgtgcg ttgcaagtca gaatccatca aagccagctg agctgcttca taagaatatt
    10261 tatcatgcat ataatgaatg atgttcaacg tattgacata tagttctgct aaccaatcca
    10321 tcatattcat gaagttatgt ttcacttctt caaagtctag tatttctgat gtgattggac
    10381 gatattctgg tccaacttgg gcgccagtca cttcatcgac tccgccattg atggcatata
    10441 atagtgtttt agccaagtta gcacgagcgc caaagaattg catgtctttt ccgacaactg
    10501 ttcctgatac acagcaagca atcgcacaat catcagaacc ccattgttca cgaagctgat
    10561 tatcattttc gaattgaatc gaagaacttt cgatagcgat tctgctagca tatgttctga
    10621 atccttctgg aaggtgttca gaatacaaaa cagtcaagtt tggttctggt gaaggtccca
    10681 tatttgttaa tgtatgaagc agacggaaat cattctttgt aactaatgaa cgaccatcta
    10741 atcccatacc tgcaatggat aaagtagccc agatagggaa tcctgagaat aattggttat
    10801 attcaggtgt acgcgcgaat ttgaccatac gtaatttcat tactaagtgg tcgatcaatt
    10861 cttgtgcttc tttttctgtg attactccat tatccaaatc acgttggata tagatatcaa
    10921 ggaatgctga gatacgtccg attgacatcg cagcaccatt ttgtgatttg attgctgcta
    10981 aatatccgaa gtatagccat tggacagctt cttttgcatt tgcagctggt ttagaaatat
    11041 catagccata tttcgcagcc atttctttca tttgcgctaa tgcacgatat tgttcagtga
    11101 tttcttcacg taaacgaatc acttcttcac tcattgtatg ataaccagtc atatcatgat
    11161 cttttttctt ttgttccatc aaatagtcga ttccatacaa tgccacacga cgatagtcac
    11221 cgatgatacg tccgcgaccg taagcgtctg gaagccctgt aatgattttg tttttacgag
    11281 cagcacgcat ttcagcagta taagcgtcaa atacaccttg attatgtgtt ttgcgccagt
    11341 cagtgaaaat atgtgtcaat tcatcgtttg gtgtatagcc attgcttttt agcgcattgt
    11401 tagccatatt gattccgccg aacggcatga atgcttgttt caaaggtttg tctgtctgta
    11461 gaccgacgat tttttccaaa tctttatcca aatagcctgc atcgtgtgaa gtaatagttg
    11521 atacgatttc tgtgtccata tcatagacac cgttacgctc gaattggata tcatttaact
    11581 tttgcaattc atcccataat ttttctgttg cttctgttgg gccttccaaa aagctgtcat
    11641 caccgcgata ttcagtgtag ttattttgaa taaagtctct agtgtctacg ccttctttcc
    11701 atttggtacc tttaaatcca ttccattgct ccattgtatg gacctcctaa atttctgttt
    11761 tatgtaacag tttttacgtg attagtataa cacagcaccc tatctttgca agggttttct
    11821 tgttttttat ttaacaattt ttatgtttta tttacatata tttaaatcaa cgttgacata
    11881 ccaacattta agcattgtga acactttcat ctttttttgc aaacgtataa ggatttatta
    11941 aaaatgaatg aaaaagagac gccacctgta ttaatacaga tggcgtctct tcattaaaat
    12001 actacaacag ttacgactcg atgaaaatct caggagcatc gataacttcg atgacttctc
    12061 cacctttttt ctcatccatc gcaaatgatc cattcgatgt tcgatcacct atagggaaat
    12121 cagttgggtc aatcgttaac tgctgccctt tttgattcat caaggttatt tcttttgatc
    12181 ttccttccga catatagata atacggtgcg gatttttttt cagctcacgc atgaccgtca
    12241 ctccccgctt cgcacgtgaa gtttggctga tttcttgagc aagcatgcgt ttaacagctc
    12301 ctcgctgagt aacgattacg atcggcgtat caccttctgc taacacaagc agcccgttga
    12361 taatcctatc tccatctttc aaattcatag acttcactcc agctgccttt gctccaacaa
    12421 cgggaacatc tgttaaagga tagcgcaaac ccattccttg atgcgttact aagaaaacat
    12481 ctaagcctgg ctgatcttct ttcagataca cagcaatcag ttcatcttct tccgccttta
    12541 gcttcataca gctgagcgga cggctcttat aggtgcgcca tggttcgaac tctgtcattc
    12601 gtgtttgctt gatcaatcca ttcttgctga tgaatacaaa tgttttctct gcttgaattt
    12661 tttgatatgg gaaaacagct aaaatcgatt cgtctacaga cagattggag attgtttgag
    12721 aaatgtgctc accagcatct ttccatttca aatcgggtag ttcatggaca gggcggtaga
    12781 tcacatttgc tttatttgtg atcagaagaa catggtccaa tgtactcaat tcacctgagt
    12841 atagcaagta gtcgccttct cgcatcccga tttcttctgg tttggaagca ctataagaac
    12901 gaaggcttgt tcgcttcaca tagccttctc gcgtcacact gacaattacg tcttcttgtg
    12961 ccactaagac ttgcgtatca attttgattt cttcgatttc gtcttcgatt gtcgttagac
    13021 gagcggaaga ataatttttt ttcacttctc gcaattcttt tttcataaca gagaaaagct
    13081 ctttgtcatt tgaaaggatt ttattcaact ctgtgatttg cgcaatcaag ctttcggatt
    13141 ccttttgaag ctctgtgata tccgtgttcg tcaaacggta taattgcaat gtgacaattg
    13201 cttctgcttg ttcttctgta aattgaaaga cgtcgactaa attctttttg gcgtcttttt
    13261 tgtctttact ttcacgaatc gttgcgatta cttcatccag aatcgataaa gctttcatca
    13321 atccttctac gatatgctgt cttttttgag ctttggctaa atcgaattga ctacgttttg
    13381 ttatgacttg ctttcgatgc tcgatataac ttcttaaaat gtctttcagt ccaacttgat
    13441 gcggagtcat atggtcgata gcgaccatat tgaaattgta attgatctgt agctcagtgt
    13501 ttttgaacaa ataattcaaa attccttgag cattggcgtc ttttttcaat tcgacgacaa
    13561 tttgcagacc tgttctatca ctttcatctc gtacttcagc tattccatcg attttcttat
    13621 tcaaacggat ctcatccatt tttttcacca aggtcgcttt atttacttca tatgggattt
    13681 ctgtgatcac gatttgctgt ttattaccct tcattgcctc tatctttgtt ttcgaacgaa
    13741 gaataacttt tcctcgtcct gtttcataag cttttttgat ttcatctttt ccttgcaaga
    13801 tccctcctgt tggaaagtca ggtccaggaa tatattccat caatttttca aggctcgctt
    13861 gtggatgatc gatcatatag attgtgccat cgatcacttc agctaagtta tgagtcggga
    13921 tttctgttgc atatccagca gatatacctg tcgatccatt gacgagaagg tttgggtatc
    13981 gagctggaag gactgttggt tctttttctg tatcatcaaa attccacacg agatcgactg
    14041 tttctttctc gatatctgct agcatctctc cacttaactt ggataatctg gcttcagtat
    14101 aacgcatcgc agcaggtgga tcaccgtcca tactcccgtt attcccgtgc atttcgatca
    14161 gtacttcccg caacttccag tcttggctca tgcggaccat cgcttcataa atactgatgt
    14221 caccatgagg atgataattc cccatgatat ttccgacaga ttttgctgat ttacggaatc
    14281 ctttgtcata cgtattgcca tctttgttca tggcaaataa tatccggcgt tgcactggct
    14341 tcaatccatc acggatatca ggcagtgcac gttcttggat aatatatttg gaataacgtc
    14401 cgaagcggtc acccatcact tcttctaaag ttaattcttg tacttcttgt cgattttcca
    14461 tcaggtgacc tcctattcta cttcaaataa ctgattgttt tcatttttat ctgctcgttc
    14521 ttcatctaat aaatcattag aaactgaagg agagatttca gtatcctctt ttttatctaa
    14581 gatactgcca tcttcttcga gcgtaaattg cacgtgattt tcgatccatt ttcttcgagg
    14641 ttctactttg tcacccatca gtgtggttac tcgacgttca gcttgcgcag catcatcgat
    14701 acggacgcgg atcaacgtac gggaagtcgg atccatcgtt gtttcccaca attgttccgc
    14761 attcatctct ccaagtcctt tatatcgctg cagcatatat cctttgccga cttttttaat
    14821 cattgctgcc aattcgtcat ctgtccacgc atattcaatg acttgcttct ttccttgtcc
    14881 tttggatact ttatataaag gcggtaacgc gatatatact ttcccagctt caatcagcgg
    14941 tttcatataa cgataaaaga aagtaagcag taatacttga atatgggcgc cgtctgtatc
    15001 cgcatcggtc atgatgatta ctttgtcgta attacagtct tcgatagaaa actcaggacc
    15061 gactcctgca ccaatcgtat agatcatcgt attgatttct tcatttttca agatatcttg
    15121 cattttagct ttttcggtat tgatgacttt tcctcgtaaa ggtagaattg cttggaactt
    15181 tctgtctctt ccttgtttag cagatccgcc agcagaatcc ccttcgacta aatacaattc
    15241 atttttctta gggtttcggg attgtgcggg tgtcaatttt cctgaaagaa gagattcgcc
    15301 ttttttacgc ttcttcccat ttcggctttc ttctctggct ttacgtgctg cttctctcgc
    15361 ttctctggct ttgattgctt tacggaccaa catctggctc atttcgctat tttcctgcaa
    15421 ataaaagccc atttgttcac tgatgacgtt atctactacg gtacgagcaa ctggcgtacc
    15481 aagtttttct tttgtttgcc cttcaaattg cagaagattt tcaggtacac ggatagaaag
    15541 tacagcagct aacccttctc tgaaatcact accttccaga ttcttgtccc gttctttcag
    15601 caaaccaact tttctcgcat attcattata agatttcgtc atcgccgctt tcataccagc
    15661 ttcatgggtt cccccatctt ttgtccgaac gttattgaca aaagataaaa cattttctga
    15721 ataaccgtca ttgtattgat aagcgacctc tacttcgata ccttcttttt ctcctgaaaa
    15781 ataaacaact ggtgtcaatg tatctttttc ttcattcaga taatcaacaa attctttgat
    15841 tccttcttcg taatgaaaaa tttccttgac tggttcttct ccacgaagat cagaaagaga
    15901 gattttaacg ccttttagaa gaaaggcaga ttctcttaac cgttcggcta aaatttcata
    15961 tgaaaatttc gttgtactga atattgtatc atctggtaaa aaatggacag tcgtcccgtt
    16021 tgcttttttt gtttttccta tctttttcaa agtaccgtca ggtttaccgc cgtttttaaa
    16081 tttctgctga tactctacgc catctctaac gatcgttaca attagccatt tcgataaggc
    16141 atttaccaca ctggctccta caccgtgcag tccaccagaa gttttgtacc ctccttgacc
    16201 aaactttccg ccagcatgca gcacagtaaa aatcacttca actgttggta ttccggaagc
    16261 atgcattcct acaggcatcc cacgtccgct atctgcaaca gttatactat tgtcttcatg
    16321 gatggtcaca tcaatctcac tgccataacc tgataatgct tcgtcaactg cattatcgac
    16381 gatttcatag actaaatgat gcaagcctcg gctgtcagtg gatccaatgt acatccctgg
    16441 tctttttcta actgcctcta atccttccaa tacttggatg gacgagtcat tgtattcgtt
    16501 gtttactttt tttgccaagg caaacgctcc ttcaataata ctttgcggca aaaccgcacc
    16561 acgattatca tactagaaaa ggtcgtgaaa aaaaagaggg tagacgagaa atcaatttta
    16621 attatctcct aaccgctttt tcgacattcc cctctatcga tcatctcttc tttgtggtca
    16681 tttttatttt tggttttctt tcaacttacc aagttcaatc ttaatacaac gatccattac
    16741 gatatctgta cgtcctgctt ttcttagcat ctcagctgct tctttgtttt caatccctaa
    16801 ttgtgcccag aacactttag catcagtttt caaaaaatca cctgctattt caggtaaaaa
    16861 ttcactccgt ctaaatacat ctacgatatc gattggatca tcgatttctg tcaaattcgc
    16921 atagactttc tcgcctagaa tttcttcacc agccaataat ggatttactg gtatgatttt
    16981 atatccattg tcttgcaata cctgtgcaac catgtaactt gttcgttctg gtttattgct
    17041 caagcctacg acggcaatat tttttgcttc ttccaaatag ttgaaaatcg tttcttgtgt
    17101 tggatttttt acagacattt ctgccacccc ttgcttttct ttttattcca tctattatac
    17161 ttgtatcttt cattttttca attgttcctg ttacctattc atgctaaaat aaaggatagt
    17221 tttcaacttg aaagagggta aaaaatgaaa ttgatcttat tacttatttt agcatatctt
    17281 ttaggttcta ttccttccgg tgtctggatt ggcaaattgt ttttcaaaaa agatatccga
    17341 caacacggga gcggtaatac tggaacgacc aatacatttc gtgtattagg caaaacagcc
    17401 gggattgttg tcctgcttat ggatatttta aaaggtacat tggctacttg tttgccgatg
    17461 atcttccacc tttctgggat taaccctctt tggtttgggg tatgcgccat tcttggccat
    17521 acatttccga tttttgctgg gttcaaagga ggaaaagctg ttgcgacaag tgcaggaatg
    17581 cttttaggat ttaatcctgt attttttgtt tattcttgta tcatctttat cgttagttta
    17641 ttttgtacaa gtatggtgag tttgagcagt atgatcagtg cagtattgat cactttatct
    17701 acgatcgtcc ttccttatgt agctcctgtg attttggcta agcccaattg gttactgacg
    17761 atcattgcct ttttagtttc ttcctttatc ttttatcggc ataaagacaa tatcaagcgt
    17821 atcagaaacc atactgaaag tcgaatcccg tttggtttga atagcagcaa gaaaaaatcc
    17881 tgatactttt tcattccaaa gagataaaac gggagtgtga caaatcgatg tcacactccc
    17941 ttattactta caggatagct tttttacaca ccttggtaaa cggtgttccc tgctaacttc
    18001 tcggtcacaa cctcttactt cactgtgatg gaatattttg tcttgaagat ttcatgggca
    18061 cctagttgat tgatccctac tttttccatc aagtttccac tactgttcac cgtgtcagcg
    18121 attccgcacc acggttcgat acaaacgaaa ggcgcttctt ttggataagg agaccagatc
    18181 cctacataag gcatatcttt atagcttaaa gttacgctat gggaagattt ttcacttcga
    18241 atggcgtacg catttagacc ccttgtttca aaaaccaagg catcttgctc aaaaagttca
    18301 cgattcaaag ccagattcgt atttgtctga cctaacgtct tttgatccat atcgatgaat
    18361 gggcctttca atggtaggcg taatcttgat ttcaatggag aaaatgccag atagaaatct
    18421 tcaaatgaca atccttcttc aagaggtaca ttgaaagcag gatgtccacc gatagaaaag
    18481 aacatttctt tttcaccggt atttgccact tgataatgaa ccgtgatgcc gtctcctcct
    18541 aattcatagc tgatcactaa ttcaaaatca aatggatact tttctaatgt ctccggcgta
    18601 ctccttaaga tgaaactagc catttcttgt ccatgttcaa tgacttcaaa atccatatcc
    18661 cgagcaaatc cgtgttgccc catttgatat gttttccctt gataaacata ctgatcatct
    18721 tttaaacgtc caacaaaagg gaataaaacc ggtgcatgtc tgccccaata cgctggatca
    18781 ccttgccaga tatactctaa accatgttct tttgatttca gactgatcaa ttccgcaccg
    18841 tgttcagcga tttcggcgat cagctggtca ttttgaataa taacagtcat tgccattcct
    18901 ccaacttcga cttacttttt aaaatgggaa ggctggaaca aacatttcta tctgccccag
    18961 tccccttact tctaataact gtgttttgct aactcgtctt taaaacggga attcaatact
    19021 tttaaataag ttcccttcat gcctaacgaa cgagattcaa tgattccagc tgattccaat
    19081 tttcgtaaag cattgacgat cacagaacga gtgatgccga tactatcggc aatattagaa
    19141 gcagtcagac gaccttcatc tccatccaat gcttcaaaga tagcttgtac agccttcaat
    19201 tcgctataag ataatgtgtt gattgccatt tggacagccg ttgcactccg tacatctgct
    19261 tcgatgcttc gagacttctg ataaaggatc tgcataccga caaccgtagc tccatattct
    19321 gctaagacta gatcgtcatc tgcaaacgat tgttccatac gagataagat aatcgtaccc
    19381 aaacgttcgc cagctccaaa gatcggaacg acagtcgtca gaccaaatgg atatttctct
    19441 cttgactcta ccggaaatgc agtaatatca ctagtaattg ggatattagc ttcagttttc
    19501 atcaactgtg ccactgtatc agtataagat tcaggaaatt gtttctcaac aaacattgtt
    19561 ttgattcgtt cattgttcac atcgtgacgt tcattataac ctagtaatac tccgtcactt
    19621 cctatgatat aggtgttgct gtcaagaata ccacctagtg tgacagccat tttatcgtaa
    19681 ggcaaatctg cttgcatgtc aaaagtattc ttttgctgca aaagtgtgtt tatcttgcgg
    19741 gttttcgtta gcaagtctgt cattgtcgtc ctccgatttt ttataaaata tagcgactta
    19801 aatcttcatt tgccgcaatt gagccaagtt tgtcatccac atatgcttct gtgatcgtta
    19861 tttctcccat ttgcatatct ggtgcttcaa ataatagatc ttctagtagt ttttccaaaa
    19921 tggtatgcag tctgcgtgcg ccgatattat ctgtgtcacg gttgacatcg aaagcgattt
    19981 gagcgatccg ttcaattgct tcttttgtaa acgtaactga cacattttct gtaccgatca
    20041 acgcgacgta ttgttttact aaagcattat ttggttcggt cagaatcttc acaaaatctt
    20101 cagctgtcaa atcatctaat tctacccgta tcgggaagcg tccttgaagt tctggaatta
    20161 gatcacttgg tttagacaaa tggaaagctc ctgaagcaat gaataggacg tgatctgttt
    20221 ggatgatccc gtattttgtg tttacttgtg aaccttcgac aattggcaat atgtctcttt
    20281 ggacgccttc tctggatact tctccagatt gctgtgattt agaagtgatc ttatcgattt
    20341 catcgataaa aataattcca ctttcttccg ctaatttgat tgcctcacta tggatatcag
    20401 catccttgac taattttgct gattcttcct tgatcaataa ctctaaagct tctttgactg
    20461 ttaccgtccg ttccactttt ttcttcggtg tcaaagcacc tagagtttca tttaggtcga
    20521 tccccatttg ctccaatcca ttgttcatca ttggtgcagg tttcttttgg tcttcaactt
    20581 caatggttac ttcacgacta tccagtaaac ccttttgtag ttgttccaag actgtacggc
    20641 gattgattcg aatatcttct gtcacttctt cttgcggttc agcggtattt tgctgactag
    20701 cattaaaaag attcatcatt tgttcaaatt gattagtgga ttgtttctgt tcttttttga
    20761 taccaggtac caagattttt accaaacgtt tttctgcatt ttttttagca cttgtgtata
    20821 cacggctgta ctgctctttt tctacgattt ggatcgcatt ttctactaaa tcccgaacca
    20881 ttgattctac atctcttccg acataaccga cttcagtaaa ttttgttgct tcgactttga
    20941 caaatggtgc attgacgatt tttgccaaac gtcgtgcgat ttctgtttta ccgacccctg
    21001 taggtccgat catcagcata ttttttggtg taatatcttg ttgcattttt tcatctaact
    21061 gcaaacggcg atagcggtta cgcaaagcaa cggcaacaga tttttttgct gcgtgctgtc
    21121 ctacgatata ttcatctaat tcacttacga tttgtcttgg tgtttgtttt aattcataca
    21181 tatctactca cctcttacag ttcttctacg ataatattat gattagtaaa gatacagata
    21241 tctgcggcaa tatttaacgc attttctgca atttctttcg cactcatgtc gttttgagca
    21301 tagtttttca ttgctcgggc tgcagccaac gcaaaattcc ctcctgatcc gatagctaag
    21361 ataccatcat ctggtgtgat aacttctcct gtacctgaaa caagaagcat ttctttatca
    21421 ttcattacga tcagcatcgc ttcaagtttt tgcatagatt gctgtgtccg ccattcttga
    21481 gctaattcga cagctgcgcg ttgtagattc ccgttatatt cgtttagttt gccttcaaat
    21541 ttttcttcta aagtaaacgc atctgcaaca cttccggcga aacctacaac aacttctcca
    21601 ttgtagatac gtcgtacttt ctttgcagtg cctttcatga caacagattc acccattgtt
    21661 acttggccat ctccagccat agcaaatttc ccgtcttttt cgacggcaca gatagtggtt
    21721 gaatgaaatg gtgattcgac catgtttgtt tcctcctaaa tttgttcttt tccttatttt
    21781 tacgctcttg gatggaaaga acgatagttt ttttgtaaac tttcttttgt tacatgggca
    21841 tagatctggg tagtcgataa attggcatgt cctagcaatt cttggactgt ccgcaaatct
    21901 gccccattat ttaataaatg agtagcaaat gtatggcgca gcatgtgagg atggatatca
    21961 ctatccaaac tgcttttttt gatcatttga ttcaagacat attcaattcc agtaggcgtg
    22021 attggttttc catgatgatt cacaaaaacg atatcatgct cttcgtgata ttttgtcatc
    22081 aatacctggc ggccttccct gaaatattct tgcagagcat cttgagcaaa agaacctaga
    22141 ggagcatatc tctctttgtt ccctttacca tggatcaaca tgacctctga atcaaaatca
    22201 atgtctgata ccgacaaact gctacactca cttaaacgga tgcctgaccc gtaaaggact
    22261 tccagtaaag cgcggttcct caaatccaaa ggactatctc ctgctacgct gtcaaaaagt
    22321 gcttgcattt cattttcata aaaaaaacgt ggcagtctca aatttttctt tttgagatga
    22381 acgtaagaaa atggattttc ttttatcact tcttctttga gaagatactg ataaaacgaa
    22441 cgtaggctgg ctatcttgcg actgatagaa tttctgctat agctaggacg atgatcagct
    22501 aatgcactca aatagacacg aaccgtaaaa tattccgcct tcagcagatc agcgtctcca
    22561 gattcctcca aaaaatgttt gaaatggaga atgtcttctt catatgcttc tttcgttttt
    22621 tctgaatatc ctctttcgac aatcaaataa cgcaaaaatt tttgttccca cgtggcttct
    22681 gtcattttct caccttcctt ttgtcccaga gaataattta gcacagcgtt tataaaaaga
    22741 caaataaatt gtcagaattt aaccaatatt tctaagtttg ttcacaattg gcgcaattcc
    22801 tcacattttg tttgagaaat tcttaagaaa aacgcaagaa aaagagcgag actatccgtc
    22861 tcaccctctt catggagttt ccttactcat ttgggattgc agttttttct aattctgttt
    22921 ttattgcctc attagctttt aaagctcgtt gtgcaattgc ttcatatctt gcttttttgt
    22981 ctcgaatgcg ctctggcagt tcaggaaaca gaccatagtt ggcattcatc ggttggaaat
    23041 gttttccttc cgcatgagta atgtagtaag ccatacttcc aatagctgtt tcttgtggaa
    23101 actcgactgg ttccatttct tttgctaagc gtgcggcgtt gattccagca agtagtccgc
    23161 tcgctgcact ttcaacatag ccttctacac cagtcatctg acctgcaaag aacagatctt
    23221 cgcgtttcgt tgattggtaa gtcggtttca gcaattctgg cgaattcata aagctgtttc
    23281 ggtgcatcac accatagcga acgaattcag cattttctaa cccaggaatc atccggaaaa
    23341 cacgtttttg ctcgccccat ttcaagtgag tctgaaagcc cacgatgttg tataaagaag
    23401 ctgcagcatt gtcttgacgc agctggataa cagcataagg acgtttgcca gttttaggat
    23461 cttccaatcc aactggtttc ataggtccga aaagcatcgt tttgaatcct cgctgtgcca
    23521 ttacttcaat tggcatacat ccttcaaaat atttttcttt ctcaaaagat ttaagttctg
    23581 ccacttcggc attgattagt gcctcatgga aagctttgaa ttcctcttct gtcatcggac
    23641 agttcaagta agctgcttct cctttgtcat agcgggactt caaatatact ttatccatat
    23701 cgatcgtagc tttgtctacg attggtgcag ctgcatcata gaaataaaaa ccatctgaac
    23761 cattgaatgc tttgatgctt tctgctaatg gatgagaagt caaaggtcct gttgctacta
    23821 cggtgattcc ttccggtatt tcagtaattt cttcgtttat cactgttact aatggatgct
    23881 ctttgacttt tcgggtaatt gtttcagaaa aagaatcgcg gtcaacagct aaggcaccac
    23941 cagctggcac tgctgtttca tctgccgaag tgattactac cgaattcaat cggcgcattt
    24001 cttctttcaa taaccctact gcattagcca aactgtttcc tcttaatgaa ttggaacata
    24061 ctagttcagc aaaattactt gtgtgatgcg cctcagtcga tttgactgga cgcatttcat
    24121 ataaacggac agggactcct gcttgtgcga tctgccaagc agcttcactt ccggcaagcc
    24181 ctgctccaac aacatttacc attttcaatg aaagaacctc ttttctatta tttttggatg
    24241 tcttcttcgt aatctccatt tacacagact acttgtttac cgcctttgac tttcttctcg
    24301 accagatatc cgtcacattt tggacaattt ctgcccactg gtttatccca agaagtgaat
    24361 tcacattctg ggaaacggga acaaccatag aatagtctgt ttttcttaga ttttcgttca
    24421 atgacttgtc cttcatgaca tactgggcaa gtcacaccga tttcttttac gattggtttc
    24481 gtattccgac aatcaggaaa attactgcaa gcataaaact tcccatattt ccctaatttt
    24541 atcaccatcg gatgtccaca gacatcacaa tcgaatcctg ctggttcatc tttgatttga
    24601 attttttcga ttttttcttc cgcattcgtc agttcttttt caaacggttt atagaaacga
    24661 tcaaccactt tgacccacgc ttccgtgcct tcttcaattt tatccaaatc tccttccatt
    24721 tctgctgtga aatggatatc gacgatttga gggaagaatt cacagattaa tgaattgaca
    24781 atttctccta gttcagtcgg ctcaaatctt ttttgtgtca attttacata gtagcgtctt
    24841 tggatcgtat caagtgttgg tgcataagtg gaaggtcgcc ctaccccgtt ttcttctagt
    24901 gcacgaatca acgtagcctc actaaaacgt gctggtggtt gagtaaaatg ttgttttggt
    24961 tcaatatcaa cagattggac tacatcgcct tcttcaagtt ctggaagaat attttctttc
    25021 tcttctttgc cgtcatctct accttccaca tacacttgca tgaatccttt gaatttgatt
    25081 tttgaaccgt tcgcaatgaa gatgacacca ttttgttcta atgtcacttt cattgtatct
    25141 aaaatagctg gtgtcatctg actagccaca aaacgtgacc agatcaatgt ataaagtttc
    25201 aattgatctt tatctaaata ttgtttgagt tcatctggtg tacgaagcac actcgttgga
    25261 cgcacagctt catgggcatc ttgtgcgcct tgagcatttt tgatctttcg gtgatcatgt
    25321 ctagaaaatt cttttccata cgtatcttca ataaatgctg cggcctctgc ttttgctgta
    25381 tcggcaatcc gggtagaatc agtacgcatg tatgtaatca agccgactgt tccttgttta
    25441 cccaaagtga ttccttcata taattgctgt gctaccatca tggtttttct tgttcgaaag
    25501 tttaacttac gggcagcttc ttgttgcagg ctacttgtag tgaaaggatt cgcagggttt
    25561 cttttgcgct ctttcttttc tactttttta acttcgaagt ctgttccatc aattctagca
    25621 gtgacttctt ttacactttg tgcatctggt aatttctttt tcttaccgtc gattccccag
    25681 aaatttgctt tgaatttctt gcgagctttt ttaaaattac cgtcgatgct ccaatattct
    25741 tctggaacaa attctcggat ctctttttca cggtcaataa taatttttaa agcgacagat
    25801 tggacacgtc ctgcacttaa ccctttcttg accttacgcc agagaatagg actgatcgaa
    25861 taaccaacga ttctgtctaa ggtacgacga gcttgctgtg catctactaa atctacatcg
    25921 atcgttcttg gttccttaaa agctgctttg actgcgtctt ttgtgatttc attgaagacc
    25981 acccgatttt tttctttcag atccaaccca agtaggtacg ctaaatgcca agcaatcgct
    26041 tctccttctc tatccgggtc acttgccaag taaacttttt gagctttttt tgctgcggct
    26101 ttcaggcttt tgatgacatc gccttttccg cgtatagaaa tataatgggg ttcataattg
    26161 ttttcaaaat cgatacccat tttacttttc ggtaaatctc ttatatggcc aacactggcc
    26221 attactttat agtttcgtcc aagatatttc tcaattgtct tggcttttgc aggtgattct
    26281 acaatcacta aatatttata cgccattact gaatggactc ctttccattg tcgtgttcct
    26341 actattaaaa gaggattcat acaaatcgta gctaatcata tccattcaga aaacgtttgt
    26401 caagaaaagc aaatgaaaag tatggtgtta ttctttaaat tctgccaaga tatcttcacc
    26461 cgaaaccgtg caaactgcac cgtcttggat caaatgatga catccggtag aatgttctgt
    26521 taaaatattt cctggaacag aaaaaactgt tcttccaaga tccaatgctt gctgtgctgt
    26581 tatcagagag ccgctttttt tcttggcttc aaagacacat gttcctttag acaaagctgc
    26641 gataatccga tttctcattg gaaaacaatg ctttttcggg ccggattgag gaggatattc
    26701 actcaaaaga agatgatcat ttgcaatcac ctcttgcaag tcacgatttt cagcaggata
    26761 gacttgctct atccctgttc caatgactgc gattgtccgt ccaccatgag agattgctgc
    26821 ttggtgaccg tatgtatcta tccctttcgc gcagccactg acgatcacat atccagcttc
    26881 tatcactggt tttagtaaat aataaactgt ttttttggct aaagcagaag tgtgtcttcc
    26941 accaacaacg cttaacatgt tacaagaaag taaagataga tcaccattat aaaacagtac
    27001 aattggcgga taggtcaagt gaagcagctg agggggatat ttgggatcaa agcaagtgat
    27061 aaacgactgt ttcgattgga ttttgcccca gttagcgtga atttcctgcc aacttttgcg
    27121 aaacagctcc cggtgtttgg ttattttacc tatcttaatg atgtcttcaa atccgatttc
    27181 tttataagga tactgcatca tccagttagc aagtgcccat tttccttgac tactgattcc
    27241 ttttgtataa gcaagtttca ataaattttc ttctatttga tacatcataa aaccgccttt
    27301 cgtctctctt tctaataaga tacgtaaaag cggctgtttt ttattgtaaa tattttttta
    27361 caggtgcaaa acttttacga tggattggcg taattccttg tcgttcaagt ccttctaagt
    27421 gttcctttgt tccataacct gcattatgcg agaaaccata tccaggataa agcacgtcat
    27481 attctttcat caattggtct cgatatactt tagcaatgat acttgcagca gcaatcgaca
    27541 cagatcgtgc atcccctttg attatttttt cctgctgaat aggcaaatcc aaggtcatcg
    27601 catcgatcaa caaatagctt ggtacaatgg acaatttttc tactgcttgg atcatcgcta
    27661 atttacttgc ttcataaata ttcacatcat cgattgtctg ctgatcaacg atcccgatcc
    27721 cgattgccag ggctttttct tgaacttgtt gataaagaag ttctcgcttt ttctctgata
    27781 attgtttgga gtcattcagc cctaatatga tctcattttt cggcaagata actgcagctg
    27841 ccacgacagg tccagctaat ggtcctcttc ctacttcatc aatgccggca atccattggt
    27901 gaccttgtgc gtacccttgc ttttcaaagc aaaacatttc ttcatatttt tccttaatta
    27961 atgcttcctt tttcaatcgt cgttcaaaag aagccagtgc ttgctgcacg cctttgcgtg
    28021 gatcatttct taatgattct agtgtaggat catctattct ctgtatgctt ttcaatcgtt
    28081 ctttgatact ttggatggat tcagtcatca cttttttgct ccatttcttc gcaacgatcc
    28141 agtgtgtatc gtccaagttt tccttgacga atatcatgca cgactaattc gctgccacga
    28201 tcatagtctt ctttataccc acgttttgct gtaatatcca tcagtaattc cggtgccaat
    28261 ttttcttctt gctcgattga taaaccataa cgatcgctga ttcttcctga ataatatcgg
    28321 gcaaaaaagt ctaatccgta aatcgctaaa tcatctaaat ggacaagctg gtctttgatc
    28381 gcgcctgtca gcgctagttt tttgccgatt tcttcatctt caaatttggg ccataaaatc
    28441 cctggtgtgt ctaacaattc caactcatta cctaaacgaa gccactgctg accttttgtt
    28501 acgccaggct tatttcctgt ctgtgcaatt ttcttgccta ctagtcgatt catcaacgta
    28561 gatttcccaa catttggaat acctaagacc attgcccgaa tagcgcgagg cttgatcccc
    28621 cgagcagcat ctcttgcccg tttttctttc aatgcttctt tagccgcagg tactagacct
    28681 ttaattcctt tactttcttg tgccgtgata gctaatgcaa gatggccttg tttacgaaaa
    28741 tattcttgcc acagctttgt ctgttgtgga tctgccagat ccgctttatt caataaaaca
    28801 aggcgaggtt tttgctgaat gatctgatct agcattggat tacgagaaga taaaggtaat
    28861 cgtgcgtcta ccaattcaaa tacgatgtcc acatatttca ttttttcaga aacttctcgt
    28921 cgggcttttg ccatatgtcc cggaaaccat tggatggtca ttgttctctc cattcctttc
    28981 ataccggaat attccccggc tttacttgtt tttttctttt tcaatataaa ttcacttttt
    29041 tattataaag aaattccatc tattagttaa gtgaaagtga accagtcctc attctatcac
    29101 atcttcactt ttttgatgat gcaaattttt attttggttt ctatatatga atctaaattt
    29161 ttgacagcgt ttcctaaata agagatgata gacgaacaaa acagaaagga gacgaaacaa
    29221 atgaatagta tggtttttgt taattttcct gttgctgatg tcaatcgttc cgttgctttt
    29281 tatgaaaagc tgggttttaa aaaaaatgaa gaattttcta ctgaagaagc tggttcaatg
    29341 gtatgggatg acactttttg gataatgctt ctctctcatg atttttataa aaaatttata
    29401 aaagataaag aaatagctga taataaaaaa acaagtggtg ctttgatttc gtttagtgtt
    29461 gaaaatgcgg atgaagtaaa aaaatttgct caaattgcaa aagaaaatgg tggtactttc
    29521 cacgaagtag atatgggaat gcctgaagaa gaaatgtttt cattagaagt ccaagatcta
    29581 gacggaaata cattagaacc cgtatggatg aagatgtaag cagataacta atctgacgtt
    29641 ttttataaca aaaaaacaaa ggcggatgat acgataagta ttctccgcct ctattttttt
    29701 tattcgtaca atctcttttt tacagtttat aaaagcagtc ttctcaccct ttttttaatt
    29761 gttagatgcc agtgtatgta aatcaccaat gtgtcatgac acattggtga ttttatggta
    29821 tccttttatt attaactgac aaaggagaga atattttgaa cactttgatt gcaaaagacg
    29881 tttttagatt gcccgaaatg aatgcaagat tgttgtcgac ctctgctctt ttattagccc
    29941 ttgatgtcat cttatacaag atagcgattg gtcctgctta ttttcaaatc acattcggat
    30001 ttttaagtat ggcgcttatg ggttatctat atggaccgat ctgggctggt ttgcttgaaa
    30061 tgttgtcgaa cactttaaat ttcacgatat ttggttcagg aacgtttcaa gctgcttttc
    30121 ttatcacggc tttccttggt ggatttatta atggcttatt tttatatcat aaaaagataa
    30181 acctgccttc cgtcatcgct gcccaattat tgattatgat cccagtcagc ctttttatca
    30241 attcttggct gatgtctgtt ttgtttggtg cagatttcaa agtaattttt ctaggtagat
    30301 tcatcaggaa tatgatccaa atccctattc aaataatggt tgtttattca tttatcaaaa
    30361 ctttagaggc tagaaaagtg tttaaacgag ctgtttgatt ttacgtacta aggtagtaaa
    30421 ctgattttgg attaaacaat aaagcgtgca gtctcaacag actgcacgct ttattgtttc
    30481 tcactggatc cattttattt catcaagtgg ataatagaca aatcttgctt tacctagaat
    30541 atcagtttta ttgatcgtgc caaacgaacg actatctttt gaaactcttc gattatctcc
    30601 aagtacaaaa taattatctt ccggaagctt ggattgtccc gttagctctt gtagtgtaaa
    30661 gtccgtcgta taggatgcat ttgcatgatc tgatttcagg tttttagtta gataaggttc
    30721 cttaactact ttcccattga tcttcaattg atcattttgg tagctgacat tttctcctgg
    30781 aagaccgatt actcgtttga tataaatcgt gccatctgct aattgaaaaa caacaatatc
    30841 aaatcgtctg atctccgaaa atttttccat cacaaccata tcaccttgct tcaacacgtt
    30901 ttccattgaa ttgccttcca ctggtaccgg gatgaataaa aatccccgca acatgaacgc
    30961 aaggaataca gaaacaagta agtatttgaa tacaagccag aagcgattaa tatagcgttg
    31021 tttttttgtc aatctctatc aatccatccc tctttttttc attctttctt tattataaga
    31081 aaaatatcaa aaaaatgcga ctagatagct gaaataaaaa taattctttc aattaggcta
    31141 ttggacaaaa aacttttttg atcataaagt acaaaactat ctcttatatg tcatgattat
    31201 tttctaaata tttttcccat gcttcgtcaa agatatccat ggacggcaaa tagtcgacat
    31261 tcagttccag ataattagaa atttcttcgt agctagagct gtgcttagga aattggatgt
    31321 ctttaccggc ttctgtagcg aaaacagata aagcatcatg tgtgccaccg cctcgcagtg
    31381 tcattaaata atgaaaaaag cttcgattca cccttcgttc ctccaatttt cttcgataaa
    31441 ggcagcccgg cgtgcatggt ttcttttaaa attttcagga tgctttttat aatactcttg
    31501 atggtcttct tctgctagat aaaatggttg ggctggttcg atttttgtaa cgattggctg
    31561 ttcgaaacgt ccactttcag ctaactgttt cttacttttt tcagcaatga tccgctgttc
    31621 ttctgtcaaa taaaagatca ccgggcgata attgtcaccg cgatcctcga attgtccgaa
    31681 agcgtcagtt ggatcagttt gctgccagta aagttctact aattgttcat atgaaatcaa
    31741 tgttggatca tagataatct ccactgcttc tgtatgtcca gtcgtttggc tttttacttg
    31801 ttcataagtc ggatctggta catgccctcc agtatatcct gacatcactg tatggatacc
    31861 aggaagcgtg tcgaaaggct ggatcataca ccagaagcag cctcctgcaa atattgctcg
    31921 ttccattatg attccccctc taatactact catccgatga ttttttattt tcttttgtct
    31981 tgctttcagt actgctggtg ctagttttgt tggtatttga gttgtttgaa gcatcagagg
    32041 tatcttttgg caaatataga ctaaaccgaa tgtcatcatt tactaagtcg attttatctg
    32101 ctttaatata catcccgttt tgcattcgga attgatccaa cctaagcatg atagtcagat
    32161 catctgtatt gacttcgatc caatctggta atttatagtt tctcttgatc atattcatca
    32221 catctttgat tggcaaactc aatgttccga tagaaagact tctagctttt agttggacat
    32281 ttccgttttc catcacatac ggatcaaaat ataaatagaa atcgatagga aaacctagta
    32341 cttcgaaagt accattgagt agtgcttcat tttccaaata aaatttatat tcaatatcac
    32401 tatctttttg atactcacta aggaaaaagc tgatgatttg attgactttt tctttatttg
    32461 aattgatcgt taagacagga tctccttgtc tttccgtaag agctggtatt tctgggagtt
    32521 ctggttcccg attagcaaaa atacggctgc ctaaaaatac ggtcgaacca agtactaccc
    32581 caagaaggat aaggaaggcg aatttccagt aatttgtttt ctttgttttg tttgaagata
    32641 cgtcagatct tgttttcatg tttattgatc atcctccttc tctaaccatt ggttttgtgt
    32701 ctcgatcagc tgatctctca ctgcatttgc catcaattga taacctaaat tatttggatg
    32761 gaaatgatct tcttcataga gcacattatt tttgatgcca tttagatttt ctgtcgtgct
    32821 agttgtttga tctgttcctt cttctgtgac acctacttcc tgattcaatc cttgataaag
    32881 caaatcattg attgggataa agtagcagtt cggcattttt tttgtcaccg tttctgttcc
    32941 tttgttccaa ttgttaacaa ttgtctgcat gtcagtgatc tcaggaaagt tcaaataaaa
    33001 tggattgtag atgcctaaaa tgtaaatagg tgcggtttta ttgagggatc gaaattcttc
    33061 caatagttct gtgacatttt cctgatagtt tttcagtggc tttttaaagg aattgaccgt
    33121 taacccgaat aaattatttt ggataacttt catcaaatca ttaccgccaa cagtcagtgt
    33181 gataaaatca gctgttttga tattgtttcg aatttcttct tttgttttta ctcgctttaa
    33241 gatctggtca cttcgttcac catttacacc atagttttct gtttcaaccg cggtcaaatt
    33301 ataacggtct tttagatcat ttgcgacaag gggaacgaat cctccttgct tggtttgatc
    33361 tcctactcct tcagtcagcg aatctccgat agctatgtag tgaagttttt cttttttatt
    33421 tggatcttct ctcacagtag ttactggttt cattagtggg ccagctttcg gtatagaagc
    33481 agctaaacct gcatagatga tgatcgcaat taataatggg aacaaaacga ggatcaaatg
    33541 tcgtttcgtt aatttcattt tttcacctct tgtattcgat tggttctaat gttatcaaaa
    33601 attttatcaa aaaggtagtc tttatgaaaa aagaaaacaa ttattttcct aattttataa
    33661 agaaaaagag aataagctgc aagcctttca ggctgagggc ttatcctctt ttcgactaat
    33721 ctacataata catgattgca aacgcgtctt taccagtatg cgtagcgata accggattcg
    33781 tatgcagtac agggatatgc atgtccggga ataattcttg caaaccctct ttgaattctt
    33841 gcgccaattc ttttgcatcc gcatgtgaaa taccgatttg tcgcacattt ggcaattctt
    33901 tcagttcatt tttcaaatta ttaaaccatt tatcgaacgt tttctttcct cgccccttag
    33961 ttacagggat taattcagaa tgggcgaaat tcatcaccac gcgtatgttc aaaacactag
    34021 acagcaaacc agttgttcgg ctgattcttc caccttttac caagttatct agtgtggata
    34081 ttccgatgta taattttgta ttgtcttgta cttttttgac ttcttcaagg attttctcta
    34141 ctgttttacc ttcttttgct aattcagctg ctcgaattac ctgaaaagat aatccttggt
    34201 cagtggtatc actgtcgata accgttactt tcgtttttgt tagattactg gcttgtcttg
    34261 ctgcttctac tgttccactc aagccttttg tcatatggat cgaaatcact tcactgccgt
    34321 cttctcctag ctcatcatac atcgagatga attctccaat tggtggttgg cttgttttgg
    34381 gcagattttt tgctttcgcc atcatttcca taaatctttc gccgtctagt tggtcatcat
    34441 cgggatatac tgttccgtcg atcatgatgg atagcggcat gacacgaatg cctaaagcat
    34501 cgcgtacatt tttttccatc gtacatgaag aatctgttac gatttttaca tttgtcatta
    34561 ttttctctct ctctttcttt aacaagatgc cttattcatg ttaaactaca tgtaagacaa
    34621 tttctatttt tagtataaca gacaaataat gatttttcat taattacacc tagtaaagga
    34681 gccgttttca tggaaaaaac gaaatttaat cgaacgtatg aaatattaaa tgaagtgttt
    34741 aatgcagtca cccatggaat tgggactgga ttgagtatcg cgggactagt ggttctttta
    34801 gtaaaaggtg cccacttgca ttcctccctc catattgtct cttatgctat ctatggatcg
    34861 atgatgattc ttttattttt aacgtctact ttgtttcatt cattgatttt tacaaaagca
    34921 aaaaaggtgt tccaagtatt cgatcatagt tcgatttttc ttttgattgc aggaagttat
    34981 actccttttt gtttgctgag tatccgagga tggctaggtt ggactttatt tgtattaatc
    35041 tggttgtttg cgattcttgg cattatatat aaagcgttga cgttgcataa acgggagaga
    35101 gtatcaaaag tatctacgat catctatatt tttatggggt ggctctgtgt cgtggctgct
    35161 gttcctcttt atcactctct tggaatgact ggtgttattt tgatggtagc aggcgggctt
    35221 tcttacacga taggcgcatt cttttatagc ttgaattcta tccgctatat gcatgttgtt
    35281 tggcatttgt ttgttatgtt aggtgcaggt tttatgtact tctctgtttt attctttact
    35341 taataaaaaa aataaagcta tggatgggac agctctaaat aacagctagt ctatccatag
    35401 cttttttata tcgtcaattc gcctgtcccg ctttttacag gattctcatt acgctgatac
    35461 gtttcaaatt gatgcggata acgatttttt tcatccattt ctccttgact agtattgatc
    35521 agtgaccaat cagaccagtc aacaggtgga aaataagcat ctccatcgaa tacatgatgg
    35581 atgactgtac ggtataatat cgtacaaaat ggcagaaatt cttgataaac agctgaccct
    35641 ccagcgatga aaaagatacc gtctgtttct ttttccagag caagcacgtc ttccacacta
    35701 tgcatgacat gcacgccttc tgctttatag gaagaatctc tcgtcaaaac aatcgtctga
    35761 cgattcggca acggacggct acccatccct tcgaatgttt ttcgtcccat cactagtgta
    35821 tttgcttctg tcatttgttt gaagaatttc agatcatttg gcaaacgcca aggaagacgg
    35881 tcttcttttc caatcaatcc gttttcatcc tgtgcccaaa ttgcagctaa cattttctca
    35941 tcctttctga ttctaaacag cgataggagc tttgatcgcc ggatgtgggt catatccttc
    36001 taattggata tcttccatct caaaatcaaa tactgactgc ttttcctgat tcaaaactaa
    36061 agtcggaaat gcgcgtattt ctcggctcaa ttgttctttc atttgttcga tatgattgat
    36121 ataaagatga gcatctccta atgtgtgaac aaattcgcca accgctaaac ctgtttcatg
    36181 tgcaattagg tgagtcagca acgcataact tgcaatgttg aacggaacgc ctagaaacac
    36241 atccccactg cgttgataca attggcagct tagccgtccc tcttgaacat aaaattgaaa
    36301 catcgtatga caaggaggca aagccatgct aggaacatct tccggattcc atgcagaaac
    36361 gatcaatctt ctagaatcag gagtcttttt gattgcttcg atcacttgtt tgatttgatc
    36421 gataaagcca ccgtcttttg tttcccagtg acgccattga tagccgtaga tgtgtccaag
    36481 atcgccgtat gtttcagcaa aggaatcatc ggttaggatc ttctcgcaaa aaagcttgct
    36541 ctgcttttta tattcttcat tgaattcagg atctgtcaaa catctatggc caaaatcagt
    36601 catatctggt ccattatagt ctggactttt gatgtagcgt tcaaatgccc attcatccca
    36661 aatatggttt ttattttgta atagatagcg gatattcgta tctcctttta aaaaccaaag
    36721 caattcgctt ttgatcaatc caaaaggtac tcgtttcgtt gttaacaaag gaaacccttt
    36781 ttgcagatca aaccgcattt ggtatccgaa taagcttaat gtgcctgtgc ctgttctgtc
    36841 ttctttacga tgcccttctt ccaacaattt tcttcctaag tcaagatacg cttgttccat
    36901 cctttttcct cctaatcttc tacccattca ctcaagtatt cccaccgtgc cattttttct
    36961 tcaagttgtg cttctgtttc agatacgtcg ttttgcaatt cttgtaatcg agtgaaatta
    37021 tctccttgat gattcatctc ttcttggagc aatgagattt tttcttcaag ttctgcaatc
    37081 tcatcttcaa tcgtttccca ttctttttgt tccatgtaag ataatttctt cttttcagca
    37141 ggttccttgc tctgtatttt tggtttcgct ttttcagcag gctgctgggt ctctttttgc
    37201 ttcagtaaat aactggacat gtttccgtaa taaagttctt gttttccgtt tccttggaat
    37261 actaataact tatctgctac cttgtccaag aaataacggt catgggaaac agtgatcaca
    37321 gcacctggaa aacttctaaa ataatcttcc aaaatcgtca atgttgctat gtccaaatca
    37381 ttggtcggtt catccaataa taaaacatta ggttgctgaa tcagcagttt caacaaaaat
    37441 aaccggcgtt tttctccgcc tgaaagtttg cctatcagtg tcccatgcat aaatcttgga
    37501 aataaaaatc gttcaagtaa ttctgctact ccgatttgac tgccatctgc tgtttttgct
    37561 tcttcagcag cttcttgtaa gtaagcaatc atccgtttat ctggtgccat ttcttcattt
    37621 tcttgtgtat aatacgcaag atgaaccgtt tcaccgatag acattgtacc gctatccagg
    37681 ggaattctgc cagctagaat attaagcaat gtcgattttc ccgcaccatt tttaccagta
    37741 atacctagtc tttcccgaga ttgaatcaat aaatctaaat gttctagcag tgtttggtca
    37801 tttatacggt aactgccatc tttgatttcc agtacttttt tccctaaacg ttgtgtcgct
    37861 aggttcagct ctaaatcatc ttcttggttt acttggtaca agttctcctt tagatcttcg
    37921 aaacggttga tccgtgcttg ctgcttggtg ccacgtgcct gtacgccagc cctcatccaa
    37981 gctaattcct gtttataaag ccgcttgcgc ttttcttctt gttctacttc tacacgatca
    38041 cgttctgctt tttctaagac gtaagcttca taatttcctt tatactcgta taattttcca
    38101 aatgaaagtt cgaagattcg gtttgctact ctatctagaa aataacgatc gtgggtaacc
    38161 atcaatagtg cgccacggta ttgtttcaaa tagttttcca accactcgat cgcttcataa
    38221 tctaaatggt ttgttggttc gtctagtaat agtaaatcgg gttcatcaat caacacttgc
    38281 gccagactaa ctcgtttttt ctgaccacct gataaagtac tgattttttt atctaattca
    38341 ctgattccta atttttgcaa aataatcttt gcgttggtat ctgtagtcca agcatcttct
    38401 ttattcattt gttcttctgc tttagcataa cgtttttgca catcagggtc ttctccgttt
    38461 tcccctagtt cgatcaatgc ttcctcatat gctcgaacag tttggatcaa ggggctgttt
    38521 ccttgaaaga ctgcttggag aacagttaat tcatcggaaa attcagctgc ttgagaaaga
    38581 taaccaatac ggtaatcagt tggataaaac actgtttgcc gatcaccgtc gctgctatcg
    38641 ataccggcaa taatatttaa gagacttgtt ttacccgtcc cgttcgtccc aatcaacccg
    38701 atacggtctt tttcgtggac caaaaaagaa atctggtcaa acaaatcttt ttcaccataa
    38761 gtttttttga ggtcagttac ttttaattct ttcaacatgt tccctcctta tcttggatat
    38821 tgtatcataa aaatagtgaa cttcaggaaa atttttttgg tatttgttct ttttgtgttc
    38881 tcaaaaaaag aacaggaccg attcgatcct gttctgatat gttttgtttt ttataaaact
    38941 tgaaaatttt taccttttta ttttattgga ctcgtttttt ttgactttgc tcgaaacgca
    39001 aatcggaaag aaaagttatc agatggtttg ttcatcgtat aagattctaa caaattgata
    39061 ttcctgcgat agctgttcgc agaaaacgtc gtgatttttt cagcaacttc gtattcatca
    39121 atgatttttc tttcaagata ataacctctt agcatttttt tcgtaaacag actatcttgc
    39181 tggatcatcc acgaagaaat caaattcccc gagttcattt ttattccttc aagtttgcgt
    39241 tgctggataa aaaattgaac catcgtttca tcataaatat cagtcaagtt atctaaactt
    39301 tcaataatca actgagtatt tttttgatat gtctctctga tttcttggat atcttcatca
    39361 ctaataaatg tctgacgatc agcatatctt ctttgccaaa acattttcgg atggagaacg
    39421 attcgcatta acctacggac aacaatgaac caaaagccga taaaagacaa aatctggctt
    39481 gtgatagaat gttcgaatcg agaaagaaaa cgggagtaaa aacgataacc attagaagaa
    39541 agcttgcccg aacgataact ttcatccaat ccatcccgtt cgatcgacaa aatcagtgct
    39601 tgtatttctt gtacttcttg cttttcatca tcggttaaat cttccaagta cagatcacgt
    39661 atccgttctt gataattttc tatcactgct tcagtggcta aaaattcttt tgtattacga
    39721 tcaatttcct ttatttcttt tcgcaaaact tcaacgacct cttctaaaat catcaaagca
    39781 ttcaaatccg tgcttttcgc ttcctctgtt tccgtcagca taggcaagac aatgatccct
    39841 atgaccaaag tcactaagat gacacccgcc gtcagaaaca aaagcaaaga ccgctggtaa
    39901 aacatcatat tattgattga aaatggcaaa ataaaaatcg tagccaaact gactgttccc
    39961 tttacaccgc caaatgttaa gatcaagatc tcgttcaact gttttttgaa ctttttactg
    40021 ccatctttga atacataaaa aagactgata gaaatgaatc tgatcacaaa aagcatgaca
    40081 gagattaata cgataatcgc taataaaaga ccgtttggat ataaaccgtc tccccatact
    40141 ggcgagaaca cttgcgtcaa ttcgattcct aaaaatataa atactaatgc attcagtgta
    40201 aaagcaatag ttgtccatgt actgtgggac aagctcgaca attctgcatc aaacacagag
    40261 attttcctaa aaccagaagc ttggagaata cctgctgcca ctgcagcaat gattccagat
    40321 acatcaaatg cctctgccaa tacataggct agaaaaggaa gcaaaagttc gatcagcaga
    40381 taccctgtga catcttgtgc tgatgctttt tcgatcaaat gaattatttt ttgtttgaac
    40441 cagacaagca aaaagccgat caaagctccc ccaatactag aaactactag actcatcccc
    40501 gcgtttactg ctgaaaaaga tccggtgatc agcgcaccaa gagcaaactg gaaggcagta
    40561 acaccagatg catcattcaa aagaccttct ccttccaaaa tatgcatcgc ctttttaggg
    40621 atattcactc gtccagaaag agaactgact gctaccgcat ctgtcggacc taacgctgct
    40681 ccaaaagcaa agcaggcagc aagtgggaca cttggcaaca ggaatgataa cgtcgcacct
    40741 accccgacaa gggtcaaaat gactcctcca aatgccaaga acaaaattgt cccgaaattt
    40801 ttgagaatcg aagaaatatc tgctttttct ccttctctaa ataacaatgg tgcaataatc
    40861 ataactaaga acaattcagg ttcaaaatcg attgattgtc cccactctgt cagacctaat
    40921 accactccaa ggaaaatttg gatcagtgga gctggaatca ttggcaaaat gcggctagct
    40981 atgttcgata aggtgatcgt tactgcaaat acaataacta actcagcaaa ttccatcgtc
    41041 catccccttt attttttatt ttgtgtaagc atttttaaaa attgttcttt tttctttaaa
    41101 attttggttt cgactacttc aacctgtgtt tggttcccct ctaattcaca ctgtacacgt
    41161 tttgactcca aacgaagcag atcatgtttc agacgttcca actgacgata catcaatata
    41221 tttcttttac gcaacttaca aagtatttga cggcggtcat ccatcgaaag ggcgccatag
    41281 cgatcatgca acagtttttt ttgttgttca aaactctctc tcattttcca gatctcctat
    41341 acacaaactt ccatcattat agcaaagttc tttttggatg aaaaatattt cattgtttca
    41401 tcgtttattg ctagttagaa atttccataa atttttcaac gcctcattct attccaaata
    41461 gtatcagata tcaagtaaaa cttaagaaag ataaaagttt ctgacaaaag gatgtttact
    41521 ttcccattcc tgcctttctt gttcttttat cacaacaaaa aaatggggct gcgacaaaaa
    41581 tcttgtcaca gtcccttatt ctgaataaac ggtgtggaag agacagccta tcagtagtaa
    41641 taagacacat ctctttcaca gcctcatttt tgcgtaaaaa tcgatttatt cgaaaaattc
    41701 cccgtataca tcttctacac gttgatctgg attgatcacg atatacaagt tacctgtttt
    41761 ttcgctgatt tttgttgatt gatattgatt gtctaatcct tctgttcctt tatctagata
    41821 tgggaagtac acaagatcag gtgtgccatt tcggtaaagg atttccattc gctcgatatc
    41881 ttcgtatttc aatgcgcgat taaacatgcc catttccagt ccgcctaggt tgatatcatg
    41941 tgtcgcaact gcgtcccctt catggaagat ttcgatttta aatccagcac acggatggat
    42001 ttcaacaaat tcactgccat tgattcgtcc aaaacttgtt gtgatttgtt tgatccaaag
    42061 atcgccgata tgacggcggt tgatcgtcca ggtttctcca tttctaaaat aaaattttag
    42121 cgctgtcatt tctttactca ttaaaaagac tcctttatga tgtaatttat tcttgtacta
    42181 cctcagttta gcacaaattt atgtaagtgg tcacatctta tgttttttct tctaatgacg
    42241 tatctgccca ctttaagtag ccaacaaagc tgagcagata cagtctagtg ttttttaaat
    42301 caatttttct ttcgataaaa aatccaaaac ctgtttttta tcatttttta ttctttgttc
    42361 tacgacggct ttttcagcta attgcaaagc ttcactaacc cacttaccag gtttttttcc
    42421 agtttcttct agcaagattt taccatctac tgctaattcg cttaatgact tgataggtaa
    42481 acgatcatag gattctccta cggcatccat ctgaggtgtt tcgtcaaaat agatcatcaa
    42541 ttcttctact tgcagtgcat gttttttgcc taagaagtac aattcgaatg gttccaaagc
    42601 tccagtttct cgttgtcgta gtccttggac aagtgcttga acgtctttaa tcatttggtt
    42661 agaacacttc cacgatttca aaaaggaacg aatctcattt tcttttagat ccagttggct
    42721 gatcaataat gcccatgctt ggctctcttc tttcaatggg acggatggta attcagcaaa
    42781 acgtaaaagt gcttcgcctt cttctttcaa accgggacag caaatgtagc actctgtttc
    42841 aataaatgca tggattcccg cggcccgttc atttcccaag agcatcttga tgaattccac
    42901 atttatacgt tctacagata ttttacctaa tagctcgtgg ttttctttga tggcgtagaa
    42961 ggtttcttcc tctaatttga accctagttg actgacaaaa cgcaacccgc gcatcattcg
    43021 taaggcatct tcatggaacc gctcatgagg attgcctaca gctcgcaaga tctgttcttc
    43081 tagatcttgc agaccatcga acaaatcgat gatttctcca tcttctttca aagcaaacgc
    43141 attgatcgta aaatctcttc ttttcaaatc ttctgccaac gaacgaacga attcgacatg
    43201 atctggtcta cggtagtcct gataagttga ttccgtccga aatgtggtga tctcatattg
    43261 ttcatcattt tctaatacca acacagttcc atgttcgatc ccaatatcta tcgtttttgg
    43321 aaaaagctgt ttgatttctt ctggaaatgc gcttgttgcg atatccacat catggattgg
    43381 ctggttcagc aagatatcac gaacacttcc acctacaaaa taagcttcat atcctgcatt
    43441 ctctaatttt ttcagaactg gaattgcctt ttggtattcc agaggtaatt gttttaattt
    43501 catttttcca acctttcctg cgtgtttctt gtcctgagat aaagactcag ttgcatggtg
    43561 actgtttgac aagtccgttt cagagtcttc aaggccagga ccacttcatc ttgtttactc
    43621 gtccttacgc tcaaagcgat tatggtctct ttgattgaat ttttccatgt ttttttcaaa
    43681 aacttcagtt aagtcgatat tcaatgaatt agccatgatc atcgtaacga ataaaacatc
    43741 accaagttct tctgctaccg agttaactgg ttcagaagcc tttttgcttt tttctccata
    43801 agtgtggttg acttctcttg ccaattcacc tacttcttca gttaatcgag ccatctgagc
    43861 taatggagag aaatacccca ccttgaattg ctggatatat tcatccactt cctgctgcat
    43921 actgtataaa gaacgctttt tatccatctt tttccctcca aaactatctt accaaaactt
    43981 taacgcaaat cctagataag agcaattgag aaaatcgaat ttccatgcta catttaggaa
    44041 ggaatttcta aatggaaatt ctgtgaaaat acataattga aagctggaat tcatatggtc
    44101 aaacgaaaaa cagtaaaaga agttcttttt atcattatag gaacaagtat ttatgcattt
    44161 ggtcttgttt acttgaacat cgctaatcat ttagcagaag ggggagtctc agggatcacc
    44221 ttgatcttaa gagctttatt tggtattgat ccagcttata cgactttatt aatcaacatc
    44281 ccattgattt tactaggagg aaagatcctc ggtaaacgtt ccttggccta tactgttcta
    44341 ggtacacttt ctttgtcatt ctttttatgg atctggcaaa gggttccact agaaatcaat
    44401 ttacagcatg atctactgat cgtttctcta cttgcgggtt tagttgcagg tgtaggaagc
    44461 gggatcgtct accgcatggg tggaacaaca ggcggcagtg atattatcgc tcggatttta
    44521 gaacaaaatt acggcatcac tatggggcgt tccctattgg catttgatat catcgtctta
    44581 cttgcttcat taacctatat cgacttgaaa cgtatgatgt atacgttgat tgtttcgtat
    44641 gttttcagtc gtgtgattga ttcgatctta gatggcggat attctgcaaa aggtctactt
    44701 gtcgtctcca acaaaagcga agagattgca ccactactga tgaccggtct gcaaagaggt
    44761 gtgactttcc tttctggaga aggcgcattc tctggtaatt caaaaaaaat catctatatg
    44821 gtcgttagct ctagtgaatt aactgaagct aagaggatcg tccacgagat tgacgaaaaa
    44881 gctttccttt caatcatcaa tgtgcatgaa gtggaagggc aaggctttac ttatttgaag
    44941 ccacagacaa gattactgaa aaaactataa gaaaaaagac aaagataggc tatgaggaaa
    45001 gattccacat ccagctgacc tttgtctttt ttagtactat actattttta actaattgtt
    45061 atgttcactt acccggttac ttttcttttg tgtctgcaaa aggatctttc ggttaacttc
    45121 atcagataat ttcaaaaaag catccctatc tccatcttct agtgcttgat cgatttgagc
    45181 ataaagcatt tttagttttg cctcttcttc tttttcttga aaatatcgtt caattaattc
    45241 agtatcttct tcactgactg aagaatccca agaagaaaat ggattgtctt ctaagataga
    45301 tagatattct cttgtctgcc aagcattttc gaatatacat tccacatata aaggcttttt
    45361 ccaattcaaa cggatttcat gaaaaatctg gtctgtgtcc gtaaattctt ttccctgcaa
    45421 aaacaatttc atgggttccc cttcaacaga tagatcactg atctgcagtc ctcgatccgc
    45481 aaaattcgcc ccttcaacaa agtggacatt gcttaaaatc gcttcatgat tggcaagata
    45541 attcaagatc caaaaaactt ctcttcggct aaaagataca tgattgacca tccacgttaa
    45601 aaaattcttc ttttcccgta catcaattag catttttctc acctctctgt taggtcatct
    45661 aataatgaca gtgcctccat atctcctggt tcaagtgtta aataataagt caataattct
    45721 tgcgctcttt tcagctgccc ttcttctctt aagaaaaagg catactcttt caagaaatct
    45781 ggttcatgtg atagttcatg ataagcctgt tcatagtgta cagctgcaac ggtaaagtct
    45841 tctaattcat tataagcatg ggctaggttc cattctgcat aaggattagc agtttcttcc
    45901 atctgattga tcacttgtat cacatcttca tatctttcat catccaagta aagattactt
    45961 aaagtaagta atgtttcatc ttgtttgtct cctacttcta aagctttcag taaaagttct
    46021 tctgctcgct gtctatcatg cagacggaaa gcattttccg aggccaggtg ataaagttcg
    46081 acttggtaag gattttcttt gattccttct tctaacactg tttgtgcttc ttcaatcatt
    46141 tcttcttctt gaagagcttg tcctagatat agatataacg attgataatg cggattaact
    46201 tctcgaagtt cttccagata gttgattgcc tgctgatttt ctttcaattg aagattcgta
    46261 aaagctagct ggaacagtcg atcatctgtc ctttcttctt tcagtgcttc ttctaaaggt
    46321 acgatagctg cttcgaattc tccttgcata cttaaggatt gtcctaaacg ttcctgcatc
    46381 gagattcctg aaatttcatt tatcccgctt gccaacaatg tttcataaac cactgctgcc
    46441 tctttgaaac gatcaactga aaaatacaat tcagctagcg caaactggat caatggttca
    46501 tcaggaagca acccagctgc ttctttcaat tttgcttcac tcacttcagg gattccgata
    46561 acttggtaca aatcagctat cgccaataag ctttgcggat agtaatcact ttgcttatcc
    46621 actttttcca ggtattcaaa agctaagtcg atctcattat cttcgattgc aatttctgct
    46681 aacgggatgt tcagtccgtc attttctggg tattggttga tcagttgttc aaaaatctgt
    46741 tttgcttcga tcaaaaagcc aatagccagc aattcttcgc ctagttcagc taatatatct
    46801 gctgggtctt cttttaatgc tttttctaaa aagatttgtg cttgtgacaa gtcttcatct
    46861 gataaagctt gcaacatttt ttcgctattt gtattcattt caattccctc ttatctcact
    46921 gacgatttgt tgaaataccg tcattgttct caataattct ttttcgtttg gatgttggta
    46981 tccgtctatt atacctattt tttctaaaac aagtattttt ttgctttttt ctgccaaaaa
    47041 aagaactttt tccaaatact ccatctttga aatctgttcc agccagtgga ttggatagcc
    47101 aagcaagtcc agccacacaa aaaagttttt tagttggaaa tcaaaaggat atgcttggag
    47161 attccacacg aaatgaaaca tcattcctaa aaattttttc atactagcag aaagtagatg
    47221 gccattttcg gtcagataaa aagcttgttc aaacagttta ccataatttg acaggttttc
    47281 tgcctctaat tgataaaaat agatcatttc ttcgatcatc ccggcaaacg gccgagtcgt
    47341 taattgcttt ttatttggat agtttttata cagattttgc aaaaaacgat gatcacaaat
    47401 cattccgcaa cagataaaag tcaaaaagtc aatctgcttt ccgtccacct gccgctcgct
    47461 gattgtttga tcataaacga tgcgttctgg cagattgatg gtttgcagca ctacacgatt
    47521 tggtagctgc aaaatcgtcc gctgcggtgt taatgctcgg cttagagaac ggatcgatac
    47581 agggatcatc catagtgatg aatcaagggt tgtatgtttt tgaaaaaaac ctgccagatc
    47641 catgatccct tcatttccaa atccgatgat aaacatggat tgattttcgg gatagcgttt
    47701 gacgaaatca agcaggttct ttaattctgt taaatgattg cattgagtgt tggcacaaat
    47761 ataccagtca ttgtttgctt gatttgcaaa taacgggttg atcttatctg caaacaaatc
    47821 ataatagcgc tgattcgtta aaaataagat tggctgatca atggaaagtt ctcttagctg
    47881 actgactagc gtttctccgt aaaacacttt cgtcaacgca tcttctactt gataatcaag
    47941 ttccatacgc atccctcctc ttcttatttt tattttacca ttagtaagca aattctagaa
    48001 aagataagag caaagctcac ctcataactt gcaaataaat aaaaattaaa taaaatacat
    48061 gtgttttcta tgtatgacat acggattcgg aatctctgtc tcttatttat tccttttctg
    48121 ctaggaaata aaaagaaaag cacttgtagc cctagagcca caagcgcttt ttcaactgtc
    48181 ttatttaaca gcgtctttta atgctttacc tggtttgaat gcaggtactt tgctagctgg
    48241 aatttcgatt tcttcaccag tttgtgggtt acgacctttg cgagctgcgc gttcgcgaac
    48301 ttcaaagtta ccaaaaccga ttaattgaac tttttcgccg ttagctaaag catcttgaat
    48361 agttgaaaat acagcatcta ctgctgcagt tgcatctttt ttagttaaat cagtagctga
    48421 agcaactttt tcgattaatt ctgctttgtt tgccatggat agattcacct cctccacaag
    48481 agatatgata gaaatatcat ttagttaaaa ctttctgagt ggtccagaag tttaaaaaga
    48541 aatattgatt aacttcaata ttctgttatc acgatatcat atgaaccgct taatagcaag
    48601 gtttttacca attttcacat gcttttttta gtcatagaaa cgtaacaaac gaaactgtct
    48661 ttttcttttg aaaaaaaaac gtcgatatgg taaaatgcct attttctcct acgagggata
    48721 attcggatgg acgtcccttc aaaagtaaat gcttttctga tttgattttc taagaaacgt
    48781 tcataagaaa aatgcatcaa ttcctcttca ttgacaaaaa cgacaaatgt aggtggtttg
    48841 acagcgactt gtgtagcata aaaaatcttc aggcgttttc ctttatctgt tggtgttgga
    48901 ttgattgcta cagcatccat aatgatatca ttcaacacag ccgaagagat acgaagattc
    48961 tggttcatac ttacttgttc gatcatttca ggcagacgtt ccaaccgttg tttagtcact
    49021 gcagaaacaa aaacgattgg agcgtaatca agataccgga attcatcacg aatctcttgt
    49081 tcgaaatcac gcattgtatt ggtttctttc tttacaagat cccatttatt cacgacgata
    49141 ataattccac gaccagcttc atgggcgtaa cccgctactc gcttgtcttg ttcccgaatc
    49201 ccttcttcag cattcagtac catcaaaacg atatcagaac ggtcaatggc acgcattgca
    49261 cgcatcacgc tgtatttttc agtattttcg tatacttttc cgcgtttacg cataccagct
    49321 gtatctatca ttaagaattt ctgaccactt tcagaaacga agtgggtgtc gattgcgtct
    49381 cgggtcgttc cttcaatatc cgaaacaatt acacgttctt ctcctaaaat cgcattgatc
    49441 aaagaggatt taccaacatt tgggcgacca atcaaactaa acttaatcgt gtcgtcgtcc
    49501 tcttcttcag tctcttcaga gaaatacttc actgcttcat ctaaaatatc accaatccct
    49561 agtccatggc ttcctgaaac aggataagga tcgcctagcc ctaaggaata aaattcatag
    49621 atatcgtttc tcatttctgg attatctact ttattgactg ctaaaatcac tggtttatta
    49681 cttctgtata aaattttcgc aaccatctca tctgcgtctg tcacgccttc gcgtccgctg
    49741 actacacaaa tgattacatc tgcttcttca atcgcgattt ctgcttgatg cttgatctga
    49801 tccataaaag gttcatcgcc aagatcaatt ccgcctgtgt cgatcacgct gaattctcga
    49861 cctaaccatt caccttttgc ataaatacga tcacgagtta ctccaggagt atcttcgaca
    49921 atcgagatac gctcaccagc gatgcggtta aaaatcgtag acttaccgac gttcgggcgg
    49981 ccaacgattg caattgttgg atttgccata ttatttcctc ctcacaagtt tccaatctca
    50041 cttagtttaa cgaatgcatt gccaactttc aagcatagat tgtcaattaa acgaagtatt
    50101 tttattcctt attgaaatac taatcgcttt tcaaaagaaa aactgagaca aaagcagctg
    50161 ctttcatctc agtcacagat acaaaatcaa ttatttttca gaatcatcgg ttgctttttc
    50221 ttctacttct tctttcaacg catcacctaa aatgtctccc atagtaaatc cagtattttc
    50281 ttctggtaat tcataagact caacattttt tggttcttct tctgaagctg gtttttcttc
    50341 taaagctttg atactcaatg caatacgatg ttcttctgga tggatctcta atactttcac
    50401 tttcacttcg tcaccttcat gaagcacttc atgtggtgtc gcaatatgtt tatgtgaaat
    50461 ttgagagata tggactagcc cttctactcc agggaacact tcaacaaagg caccgaagct
    50521 tgtcaaacgt ttaactgttc cgtctaatac tgtgccaact ggagcttttg tatcgatttc
    50581 tgaccaaggt ccaggctgtg tgtctttgat tgacaaggaa acacgttctt gttcaggatt
    50641 gatagacaac actttgacat ttacatcatc attgacagcc aatacatcac ttggttttgc
    50701 tacatgacta tgtgaaatct ctgagacatg gactagaccg tcaattccgc ctaggtcgac
    50761 aaatgcgcca aaatcagtaa gacgtgcaac acgtccactg agaacatctc cctcatggat
    50821 agttgaaaga atttcttttt tcttttcttc tctttcgttt tccactaccg ctttatgcga
    50881 taagatcaaa cgattttctg atggttcgat ttcgatgatt ttaaagctca atgttttgcc
    50941 tttatagtct gaaaagtctg caacaaaatg atcttccacc attgatgcag ggacaaaacc
    51001 acgtacaccg acgtcaacga ctaaaccgcc tttgacaaca tttgtaacag gtgcttcgat
    51061 gaccttgccc tcttggaaat ctctttcgat atcttcccaa acttttttag catctaaacg
    51121 gcgttttgaa agtagatagc tgccgttttc tttatctttg ccgatcgtac tgataacgac
    51181 taaatctaat acatcaccga cttttactac ttcgctgata tcttctaccg gcaaagttga
    51241 taattctttt gccggaacga ctccttcaac tccagcccct tcgattccga caatcacttg
    51301 tttgtcttca atgactaaaa cttcgccctt aacaacatcg ccaactttta cttcttgtac
    51361 gcttttcatt gcgtcttcca ttgactggtt gttctcttga ttttgatcaa attctgtcat
    51421 aacacttgtc ctcctaacca acattctgcc gtaagtacgg tactgttttt agtttaattg
    51481 attattcaaa aaaaataaag cgatttcgtt cgttttcctt gaaaaaacaa ttgtttttca
    51541 ttttttttct taatttaaaa aagaagataa ccttttttca aaacaacagc ttttattgct
    51601 gcaacgactt ctggaatcga tttgccagtc gtatcgatac gaacagcatc ctctgcttgc
    51661 ttcagcggag agacgtccct tgttgaatca taatggtctc tttcctgtat ctctttcgtc
    51721 agtgtttcaa gatcagtcgg aattcctttt tcttggttct ctttgaaacg tctttctgca
    51781 cgctcactta cgcttgctac taaaaagatt ttcacttctg cattcggtaa tacagctgtc
    51841 ccgatgtctc ttccgtccat gacaacgcca ccgcgttccc ctatttttcg ttggacagca
    51901 actaattctt ctctgacttt tccatgtgca gagacttcag aaacagcttt tgtgacatct
    51961 ggttgacgga tttctaaagt cacatctttt gatgctatga atacatgctg tccatcttct
    52021 tgttgcgaaa aagagatagg atactttttg atcagcgaaa ctagcccttc ttcatctgaa
    52081 aaagatacat tgttcgtaat agctaaataa gttactgcgc gatacatggc accggtatct
    52141 gtataaatat aattcaattc ttttgctaat atcttggcaa cggtactttt cccagatgaa
    52201 gcaggcccgt cgattgcaat actgatttgt gtcatgatat aactcctttt tctcagaaaa
    52261 aaagccgcaa agcgcggcta ttattattta attcttaatt cttgaccagg gtaaagcata
    52321 aagttgtttg gatctaagcc attcaattca aacaattgat cagtggtgat ccctgcacgc
    52381 tcagccactt gttttggacc ttcgcctgct tgaacagtcg ttgttgaacc ggctgcagct
    52441 gatgaagaag gtgttgtttc tgctgcattg ctgcttgaat cccctgcttg ataagttgcc
    52501 tcacttgagg aagtcggtgt tgtctctgct gcaatactgc tttctgacgt tacacctgta
    52561 tcttgagaca cagtagattc ttccgcgatt gtactagatt ctactgttga agtctcagtt
    52621 gactcctctt ttgttgtact tgtagaactt tctactactg atgtcgaagt ttcagaagaa
    52681 gttgctgctg ttgcattgtt gcttgatcca tttctgatcc agaaataagc acctgctgga
    52741 atagcgatac ataagaccag taaaatcaaa aatagcgaaa gaaataatgt atttcctttc
    52801 ttttgttgtc tctgagaact tcttgatgaa acttcatcat ctgtatcgta gattggttgt
    52861 tcccatggtt cttgtgtttc gttattttct gtagattgat gtctatcttt tctgctcact
    52921 gttttacctc ctaaactcta tcgtgtgtat tataccatag gaaaaagtgt cttgtcctaa
    52981 aaaatcaatg ttccatgttt tttttaaata aatttagtaa aatcgttccc caatgaagtt
    53041 gttcagtctt agaaaaaagc ttcctctttg gcagaagttc tgcttttgct ccatcaatat
    53101 cacaacaatt ctgcggcttt tcggagagtt tttcgccaaa ataagctaag atgaattttc
    53161 tgcggcagtt ttcttcatta atatagcgaa gcatctgctg caggcggaat tctttttctt
    53221 tttcctgacg tttgagccgt tccacccaat tttctggttt ttcagactgc tggatcagct
    53281 ccatccattt tttttgcagc tcatcaaagg gagcttgctc tgtggcatat tccaaataaa
    53341 gctcaaaact ttgtcgctgt tctctagaaa gttgattaaa gaaataatgg atacgttcat
    53401 ccccactttg ataaaaaaga attgctgcac tttcttcctg atctctgcct gctcgaccga
    53461 tttcttgtac atagttttct agactgtctg gcaaatcata atggaccaca taacggatat
    53521 cagatttatc gatccccata ccaaatgcat tcgtagcaat gagaaactgc agctgatttt
    53581 ttacaaactg ctgttgaagt tgtcttcttt gagctgcatc aagaccaccg tgatagtatc
    53641 caactgtaaa acgttccctg aataaatgat acaatcgttc gacttctttt tttgttgcac
    53701 aataaatgat tgccgctcct tgtgctcttt ccatgaagtg ttcaagttct tgttcttttt
    53761 gctgcgtttt ccgaacaaaa agcgagatat tttgccgatt gactgattgt ctgatctctt
    53821 ttggtggtcg atcaaatagt acatgacgta tatctcttgc tactaaatct gttgctgtcg
    53881 ccgttagtgc cagtgtgacc gggtttccta aaagctttcg gatttttcct aactgttgat
    53941 attctggacg gaaatcaact ccccattgag acacgcaatg agcctcatct actacatata
    54001 acgcaatatt ttgttttttc agatgctcta aaagagaagg attagtcaac atttcgggac
    54061 tcaaaaacaa aaatttatat tgcgatagat gacggaggac gtatcttctt tcagattgcg
    54121 aaagtaaact attgaaagca gctactcgtt tctcccctcg tttttgtaat tgcgtcactt
    54181 gatcttccat tagagaaagc agcggtgaca cgatgatgac cagaccttcc attaaatacc
    54241 ccgtcaattg atagcaaagg ctttttcccg ttcctgtagg caaaatagcg agagtatctt
    54301 ctccatcaag caacgcctga ataatttctt cttggccggg acgaaatgaa tcaaatccaa
    54361 aatatttttt taattcattt attaacattc tgtatcgctt cctttctcaa tagatagatt
    54421 tgatacaaac gaaattctcc ataatctaat tgtccatcta cattccattc gctaaagcgc
    54481 cactctcgca cggaatcctt atttggttcc aaacgttcga ttgtttctgc agagagaatc
    54541 cactcgtatg gaaaatcatc aaaaaacaag gcccactcaa taagatgatc tgttactgtt
    54601 cctcttttta aatgacggat tgccatgatc tggtcaattg tctgaccatt cataaacatc
    54661 tgcttggtga tcatcatgct ttgattgaaa ttttgctgta ataatgaatc gatcaaagcg
    54721 tgccaaagcg aatctggccg tttttcgatt tgtgctaaca aaaggtggat acatctgctt
    54781 tgttgcagat aaaccgctga ctcatcattg ttttttgcca gctgataagg aagcagccct
    54841 gttcgctcat ttccagataa ttggttagct aaaaaatctg ctgcttcttc tggtatctcc
    54901 gaaaacagct gcaccaaact ctcatacgca gtatcaatca aaatttcacg tggcaattgg
    54961 ctttcactaa gccatttttt tagttggaaa gtataaaaag gacttgtctc tgctggaaga
    55021 tagtcttgaa tacccgttgc cagattagaa attacttgaa cagcaaattt aatgagccgc
    55081 caactagttt cccctgttct gccatagcgg tcaaaacgca aaccagtatg ttctatttga
    55141 tgttcggaca acatatcagc ccctgcaggc gttagctttg cttcattttc atttatttcg
    55201 atccaacctt gctgcgcaat tttttgcaaa atttgataaa acttatcctg cttcaattct
    55261 ggaaaactgt tatggataaa caaaagttcg tgggtaaatc cataaataag tactgaagtc
    55321 gttcgttttc ccacaaggag ttggtaaaga gaactaatcc gcagcttgtg tcctgatgaa
    55381 aatagcgata aaataaaaac aatcatatta ttctccttaa gttaggatgg ttagaaatgt
    55441 cactactatg taaacttgta cctgaacgct gtattgcatg cggtctttgt caaatcgaag
    55501 cgccagatat tttcgattat gatgaagaag gaatcgtttt atttgcccaa gaaccagagg
    55561 ctcatcaaca gttcgtgatg ccggaagaag aaacatatgt aaaaaaagcg tatcaaaaat
    55621 gtccagttcg agcgatttta ttagaaaata aaatataaat ataaacgaaa ctttaaaaac
    55681 gtacactaag ttctctaaac ttgaaaataa gccgggatct gtttctcttg ttccgtgaaa
    55741 tcccgactta ttttgaaaga ttcatttgct atctatagtt aattgactag ttttttcacg
    55801 gaccctatag gacccattta tattatttca actttttcag ccagttttcc aatgtattga
    55861 cgatcacagt ttgctggtct gcgttagaaa tttctgcctc tccatctcct ttttgctcac
    55921 catagctgcc aaaacctcca tgatttccgc cattgattga tacatactct gttctttccg
    55981 gtaaatactg cttagcttct tgataagctt cctgattcaa tactttatct tttgtcgccg
    56041 tgatcgataa aacaggaaca gctgattctg tcaatgttcc ttttttgtcg ggataacttg
    56101 ccatgaagaa tacccctttt aaatgtttgt ctgaatgatt cttattgaca taacgacttg
    56161 ccattacgcc acctaatgaa tggccaccga tcacataatc ggaatttgga aaatcttctt
    56221 tgaccttatc cgctttgttt ccgcccatca ctgctagatc aagtggcatt ttgacaatag
    56281 cgactgaaaa gccgtttttt gctaaatctt gcgcccaaat actataactt tctggctcta
    56341 cgagagcacc aggataaaaa ataagtaatg gagactttcc atgattcttt ttctctcctt
    56401 caaaaaataa gtaatcttct ttgttttttc cttcttttac caacacttgc gcttctgacg
    56461 atggttcgta cgtattttgc tgtatatagt aataaccggc tccaccgagt aatcctaaaa
    56521 tgatgactaa gccaattagt attcgtctaa atattttcac tttctcccac cttttctatc
    56581 tgagtgaccc ctttttctta atcaagtatg attatacctt aaaaaaataa gagagaaatg
    56641 caaactttcc agcatcaaat aaaaaaagac ggaatatcca tttgaatatc cgcccttttt
    56701 gtatgtttat ttttatttag cacataaacg atacacagct tctgcataaa tttccattgc
    56761 tttatacata ctacttaatt cccatcgttc attcgcctgg tgcataaagt caggagtatc
    56821 agggaacatc gcaccgaatg ccacacactg gttcatcgta cgagcaaaag tagcgccgcc
    56881 tgatacaaac ggttcagtca tgtctccagt aatatcgcga tatgtcccca atagattttt
    56941 cactaactca ctgtctagtg gcacgtataa tgaatcaagg aagtcaaatt cttcataagt
    57001 caacccatat ttttctgctg ttttagttaa tttagctact aaatcatctt tcttgaatgt
    57061 aacagggatt ctcatatcta caccgatttt tgtttgttct ggtgtgattt ccaaacttgc
    57121 aaagttcatc gttagctcgc cggattgttc atcttctgtt ttgcccacga cagcttcacc
    57181 agttgcattt tcttgaacta attttcctaa gaaattgatt gggccaaaat caaatacttc
    57241 tgaaagagca attgccagac gagaaatagc attcactcct tgtgctgcat ctttcgcgtg
    57301 gatactttta ccaagaacga cgatgccttc accttgttct tcgaaatcga attcgtgttt
    57361 tttcaatgct tcttttactt cagaaagctt ttctccagag taaggagctg catcaggaac
    57421 aacattcaac gctcctccag cttttacaga aaactcgttc gttcctggtc ctgtcaagta
    57481 agcttgcaat aagccttttt ctgcataaat taaaggaaat tcagcatctg gcgcaaatcc
    57541 ttgcgtaatt ccttcttctt tttcgttata tttttctaaa caacgccata aattttcttc
    57601 atctgtacca aagataaaac gaatacgtgt cttgaattcc acgccagcat caatcaaagc
    57661 tttgacggca tacattgccg caatagaagg acctttgtca tcttgggatc cgcgaccaac
    57721 taaccagccg tcttttatag ttggatcgaa tggttttgtt tcccaattat tttcgtcccc
    57781 tgctggaaca acgtccatat gacacaagat accgaataat tcatctccag agccaatctc
    57841 tgaataaccg taatagcctt ctggatcttt aaatgttcta aatcctagct tttcactgat
    57901 ttccaatact ttatccaaag cttcaatcac ttttttaccg aagggatgtc cttgtcctga
    57961 atctgcttca tctagtacgg aaggaattcg gatcaattcg ctcaatgatt ctaatgcttg
    58021 ttcatgatgt tgttctgtca caaatttttt catgatatta tcctcctaat atgttaaaaa
    58081 gggtcatgtc aaattcctcc gacacaacct cttcttctca aataatgacg ttttaagcct
    58141 gctccatcag caagcagaat gttcttaaca aatgatgaaa gaaaaaacac tcactgaatg
    58201 gagctattga cttatccacg tgcttatcga tagccgttta tcggtttctt cattcttatg
    58261 atagaccttg tacctgtatt tgtctaggtt tagaacattg ctgctacacc taggatcaca
    58321 cagatggcta caaataatat cgcaattaat ttaccggtaa atttccacca cactgaaaca
    58381 tcgaaacgag caattgctac agcacccatt acgatagcag atgttggtgt aattaagttt
    58441 actaaaccag atgcagattg ataagcagtg attactaaat ccttaccgac gccggcaaat
    58501 tcacccatag gtcccatgat tcccattgtt gcagcagcta agccggaagt tgaaggaatc
    58561 aagaatgaca tagggatata gaaaataaat gtaataatga tgaatacact tgaagataat
    58621 gaacttaatc cttgttcgcc ccaatgtaag atggtgtctg tgattaatcc attgttcata
    58681 accacttgga taccacgagc aacagctact acgattgcta caccgatcaa atcagaagca
    58741 ccagctaaaa attcagagac aaattcagac tctttcatgc cataagtgat tgctactacg
    58801 atggacatta ctaagaataa catagtaatt tctgggaagt accagtcacc taatggaagc
    58861 atgcttttac ctagaaccgt acctagtacc ggaaggtttg ttaaccagtt tgtcaatgat
    58921 tcaaaaatcg tgaaattcgc attcaaggtt gtccaaggaa tcaaactgat gatcatgata
    58981 ccaaaagtaa taaagaacaa tacattaaca tgtttttgtt ttttcgtgat tacttcttga
    59041 cgaccgattg cttcaatatc gaaatgcttc atatcttctt tacgttggtt gtatactaat
    59101 gattttgttg gatctttttc gatctttgat gcataacgat acacatatac aatagaaata
    59161 gctaacaaaa taacgaacat caagaatcga agaccaatac cttcacccat cgaaatccca
    59221 acagcttgtg aagctacgcc tgttgcaaaa ggatttaccg ttgaagctag acagcctact
    59281 tgagacccta ctaatacgat tgctacagct actactgtat caaagcctac agccatcatg
    59341 actgggatca gtaaagcata gaatggaatc gtttcttctg ccattccgta agtagagccg
    59401 cctaatgcaa ataacagcat caatactgga ataagcattt tttcttttcc tttgaatttc
    59461 ttcacaactg aagcaatccc ggcatctagt gcccctgttt tgttgataat acctaaaaat
    59521 ccaccaacaa ccaaaatgaa gaaagagatt gggattgcag caggtgtttc tttagttagc
    59581 tcccccgctg gtacacctag catcccattg attggcgcca tgaaaatatc ccacagccct
    59641 tgaggatttt gttgtactcg ttcatatgat ccagcgacga tgttgcctgc atcgtctaca
    59701 ctatagtgcc cagctggtat aaaccaagta agtacagcga ttactgcaat aataataaat
    59761 aagaccgtat acgctgaagg catttgaaat tttttctttt ttgtttgttc catcttcttc
    59821 ttcctttctt ttccgttaga gacaacaatt ttggctctaa tgttatttta tcaaaaagag
    59881 tatcagaaca aaaataataa cacgcatttt gtaaaacttt tgttcaaaaa gttcgttttt
    59941 ccctattccc tcctcttttt tcaggttttt aaagctttct tctttttcat tgtagcgttt
    60001 cctttttttt ataaacaaac attttcgtct tttaaaagga gaagaatttc acatttgcaa
    60061 agaattgatt gatttttatg cataaatcaa aaaaatactc aaaacaaaca aataaaacgt
    60121 ttacattatt gcatgtcttg tatttttttc caaaaaaaaa gaccaagaaa tttcttgatc
    60181 tttttgatat ttatttgact gctgtatgac gttgttcgaa ctgatgttgt tttcgactta
    60241 accatggaag aagttgcgca tgcagcacta aaaagacagc actcacgatg aatcctttga
    60301 tcaagttgaa aggaacgatc ccaatcagta catagtttgc taaagacatg cccagcatct
    60361 gtgttgcgtt cagccctaaa aacattaagt aaagaggcgt aataacgaaa taatttgcga
    60421 tactcataaa aatagttaga gcgatggttc ctgtaatgac acctaaaaat ttgtttcttc
    60481 ctttatgctg tttctttaca ctaaagaaat aataaatcgg gaatgtaaag atcgttgttg
    60541 ataagaaact agcagtgtct cctaccaaat tatccggaga aaaacctgta gtcagcagat
    60601 gtaatactga acgcaagaac gctgttgcaa ctccggccgc tggaccgaat aagaacatgc
    60661 tgatcaatac cgagatatca ctaaaatcga tcttcaaaaa actaaaagcc ggcatgatcg
    60721 gaaaagcaaa atactgtaaa actaatgcga tcgcagcaaa catcgctact gcaaccattt
    60781 tctgtacacg ggtgttcttc atttgaaatc ctcctgttag gactcctctt cagcgaactt
    60841 tttgacgttt ctctccaaat gaaaaaactc tattttccag ggaaaataga gttagagtta
    60901 tttgatcaag cgtcgtcaaa taagctctat cttctttatc cagactatac tgtcggtatc
    60961 ggaatttcac cgattcagct atttttttgc aaaataggtc gtggactata accaccggtc
    61021 gggaatttca ccctgcccct gaagacgaac cttatataat ttttgtttac atattcatta
    61081 tacatatcta ttcaaaaaac gcaacatcta acacttataa aaagtaagtg ttcattttga
    61141 gtggttcagc aaactgctga cttctttttt gttcagttca cggtaatccc caggacgtag
    61201 gccttgtaaa gtcagatctc cgtatttttc acgttttagt ttttgcacag gaagaccaac
    61261 tgcttgaagc atatttttca cttgatgatt acgtccttcg tggatcgtca attccacgat
    61321 actgtggttt gtcttaggat ccactgataa aatttggaat ttagctggag atgtttttcg
    61381 tccttcgatc tttattcctt ttgtcaaagg tgcaagcatc gattttgtag cgatcccttt
    61441 tacctttgca acgtaaactt tatccacttc atgttttgga tgtgtcaggc gctgagcaaa
    61501 atctccatca tttgtcagta gcaagatccc cgaagtatcg taatccagtc gacctacagg
    61561 atagatacgt tcttttacca tcggcaaaag atccgtaaca acttttcttc ctttgtcatc
    61621 tgcaacagca gaaataactc ctttaggttt gtacaataaa tagtaaccgt attcttcttg
    61681 ataaattggg acttcatcca cttccacagt gtcatgtttc ccaactttta tccctaattc
    61741 ccttacaact tgtccgttta cttttacacg tcctgcaagg atgaattctt ctgcttttcg
    61801 acgagaagtg atgccagcgt gggcaattac tttctgcaat ctctccatta caattattct
    61861 cctttattca ttccatcaaa gaatagatct ggtgacacgt cttcttcaag tgaaatttcc
    61921 atttcttgtg tatcaggcag ttcttctaat gatttcaaac caaaataatc taagaagtag
    61981 ccagttgttc catataatat cggccgacct ggtccttcta ctctaccttt ttcttcaatc
    62041 agtttatggg cagctagacg ctgtaccgct cctgaaacct gaactcctcg aatctgctcg
    62101 atttcagctc ttgtgattgg ctgtttataa gcgatgattg ctaaggtttc gacggcggct
    62161 tgagataatg tgtttgatgt cccttgcgca tatcgcttaa gtaagggagc cagctctttt
    62221 ttagtcgtta atacataatg gctttccgtt tcaaaaatat gcaaagctga gtgcgagttt
    62281 tgagtgtaag attcttttaa ttctttcact aaacttgtga cttctgcttc gctgagattt
    62341 aacagtccgc ttaattcttc attactgatc ccttcctcgc caacaataaa aagaagggct
    62401 tcaagttcac ttaatttcgt catgttcggt atctcctact gctggataaa gcataattga
    62461 ttcatagttt tctttttgtt gcgcaatgat ctgccctttt ttcatcaatt ctagcaaagc
    62521 cataaaagta gtgacaactt cacttttaga aggtgactca aaaaaagaat cgaaagtaca
    62581 gccatgcgca tttcttttta tacgctcttc gataaatacc attcgttctt cgatcgttgt
    62641 gtcatcgggc gtgatcgttt tttccacttt ttgagaaaat ttcttacgtt ctaagatttt
    62701 ctgcatggca cggatcaaat cgattttttt gacttgtcct cgcttcaacg gcttttcagc
    62761 atccgctaac ccatcgatgt tcataggttc ttttgtgtaa taaagacttc gttcctctgc
    62821 tttttctgtc agtctttcag ctgcatattt atatttacgg tattctaaaa gctgagtgac
    62881 caattcttct cgaggatctt cttcccataa ttcttcatcg tctgtgacga attcttggac
    62941 aggaagcaat gtcttgcttt tgattgccat caatgtagca gccatcacta agtattctcc
    63001 tgcaacagct agctcgagtg ttttcattgt atggatataa ttcatatatt gctccgtgat
    63061 cgtagcgatc ggtatatcat atatatcgat ttccatttgc tgaatcagat gaagcagcag
    63121 atcgagagga ccctcgaata catctaattt aatattgatc tccgtcaact cattcactct
    63181 ttcttctttt tctttgctag ccattttcca atgtaaggct ctgtgatttc agttgcacgg
    63241 atggagacat ccgggtactt ttcctgtaat tcatctaaca tttgaaagcc catattctca
    63301 ccgcgataag acggattcaa agaaatgtca tggatgatca gctgatcgtt cgttgcccag
    63361 taaataccaa taatcccttg aatgttggtt gaaccttctg gcgtaaagaa aaaaagttca
    63421 taatcgtctt cagattcgta cgtatcaatc tccttcaaca aagaagtttt acctgtcagt
    63481 ttcttatgga aactcaatag tcccatagca attttacggt tttctttccg gtaatgtgtt
    63541 aacatcttct caccttccta tgactaagcc cttggaaaat gctgcttata aacatccgtc
    63601 attcttttct tcgtgatatg tgtataaatc tgagtcgtag agatatccgc gtgacctaac
    63661 aattcctgta ctgtccgcaa atcagctcca ttttctagca gatgtgtggc aaagctatgc
    63721 cgcagcgtat gtggtgttac ttctttgtaa atcccagcct ctcgtactaa ctgcttcaga
    63781 tttttccaga ttccttgccg agaaagacct ttcccatgat tattgacaaa tacatgcatt
    63841 tcagatgcgt cctttacaag taatggacgt gcttcgtcta agtagcgttc cagccattgg
    63901 atcgcataat cacctaaagg aatgatccgc tctttatctc cttttccaac tgtctgtacc
    63961 agtccaagag aaagatgaag atctcccaat ttcaatccaa tcaattcact gacgcgcatc
    64021 ccagtagcat acatgacttc caagattgca cgatctctta tccctaacgt ttttgtcgta
    64081 tcaggtgctt caatcagctt ttctacttct gtcagagtca atgtacttgg taatttctgt
    64141 gctttcttcg gcgtatcgat atgttgcatc ggatcatgat cagtgatacg ctcttgccgt
    64201 aaaaactgat ggaatcttct gagacttgag atcatccgag taacagttgc tgtcgctttt
    64261 ttttcttcat gcaacttctc cagaaaacgg atgactaaaa agcgatcgac atcctgccat
    64321 gaagcaattt tctgctcctg tagaaaatgc aagtactgtt ccaaatcacg ttcatagctt
    64381 tgtcgtgtat tggcggacaa tccccgttca atattcaagt agtggagata atcgttgatt
    64441 tgctctttca taataatccc cctcatgcct ctctatcata tcagataccg cttcattctg
    64501 atagtctttt tccataatct gagcaaagaa aaagccgtct agacactcag acggactggt
    64561 ttcttttttc tttttcatag cattcctgac agattccatg gaacgttagc cgatgatctt
    64621 ttactaaaaa atgataacgt tcttctacta cttgctccac ttcaagtaaa agatcctctt
    64681 ctacttcctc gatcgtgccg cagttcaagc atagtaaatg atgatggaaa tgtttggcgc
    64741 cttcttttct caaatcataa cgggctaatc catcattaaa acttacttta tcgacaattt
    64801 tcaattctgt caagatttca agggttcgat aaacagtagc aagtccaatt tccggactct
    64861 tttttttcac taaaaagaag atttcttctg cagataaatg ctctttctca ttttccaaaa
    64921 gcacaagcag agtagcttct ctttgcggtg tcagcttaaa ccccgcttca tgtagctgct
    64981 gttttgtttt tttcatcgcc gaaatagcat tcatgaccat ttactcaacc ccaacaattt
    65041 ataataatta caaataaaaa aagatataac actatgttaa ttaaaattat tataagctag
    65101 ttaagaaaaa catgcaaggg attctcaatt agattttttg actagttttg tcacaccgtt
    65161 ttcttgtgta atcaatcctt gtttcaaaag attacctaat gcgcgcttaa atgctccttt
    65221 gctgatacca aaagctttca tgatttcttc tggatccgat ttatctgtaa agttgatttg
    65281 ctgatctgca gaacgttcta aaatggttaa aatcatttgt gcatcatctg atatagcttc
    65341 atatgctctt ggcttcaatg aaagattcag tacaccgtct ggtcggacac caatcactcg
    65401 accttttatc tgctcgccta gacgaggttc attatatcgt tcagaaggat ggataaaccc
    65461 aagatagaaa tcttccgtta aaacgtacgt acctgttaat ttcaagcggt atgctgttcc
    65521 tatcacatct ttgtttttca tttcttctgt tccatatttg cttaaagatt tgaatatttt
    65581 ttcatctgct aaactgcccc aaatacggtc ttttgcatca actctaaggg aaatcatcaa
    65641 gcgatcccct tttttaggcc atagctctgt cattgtcggc aattcatcaa gagatacgac
    65701 aaagtcttta tctggaagac cgatatcgac aaacgcacct aaatcttttc gtgtagcagt
    65761 aacgattcca aaagcgtaat gaccgatacg gcttttagga atttgtgtag tgatccgatt
    65821 ttcatgtttt tgattttggt aaccgaatcc ttcaactgct tcaccgattt tgtgttcacc
    65881 ttctgatttg cttaagccaa aggtttgtcc gtttttttgg acaaagtagt ttttttcatt
    65941 ttcatcaata ataatacctg taaatatagt tgctaataaa tcgttcattt ttttctccct
    66001 ctatagtgaa aggttttctt aatacatttc tttgctatca taacataatg ttatctactt
    66061 gaatagctga gccttggttt ggaaaggtga aaaaaggagt atgacaacag ttgtgtcata
    66121 ctcccctttt tcgaataaac ggtgttaaac ggcaggctca cagcctcttt catttgccta
    66181 aaattaattg ctcccatttc ctccgaacca tccagtttta cagttgatgg ttacgatgta
    66241 aaatggcaaa gcactttctc caatgccttt catcaatgca gattttgttg aagtggcata
    66301 tagattataa tagccttccc cattttcgat tctggctttt tctaatctgt aacctccttc
    66361 aacgatatat ccacgttgga tacatgtagc aatcactttg ctttggacac ctggtgccca
    66421 cgtccatgct ggattagatg catcggcaat atcacttgct ctggcagatt tgattggctg
    66481 attcgctgag tttgaagagg aaggggtcga ggatgccgct tcttgctgtg ctgcttgtgc
    66541 gaccgcagct tgttgagcgg cttgagctgc agctgctgct tgagcggctt gttttgcttg
    66601 ttcttcagct gcttttttcg cttcttctgc ttttttcttt tcctcttctt cttttttctc
    66661 tttatcagtg agcatcttat ctacttgttt caattgttca ttcaactgag cagatagatc
    66721 tgtatttttc actttttcta ctgcttcttt tgccgtcttg tattggtcgc gtgttgctga
    66781 atccactact tttccgtctt taaagactat agctgttttt tctttagctg tttgcaattc
    66841 agcatattga tttttagctt ctgtttgtgc ttgttgaatc aattttccaa aatctgtgtt
    66901 atccgtttcg attgcttgga tctctttatc tgctttcaac ttgatgtcat ctgctagatg
    66961 atcatcgacg atggcaggtg ctatgaacca ctcattcact ttttggatat ctcggatctt
    67021 agattggata tcttggtaag ttgtttctaa ctctgaatat cctttttcat tcttaagact
    67081 ggataaatca ttttttagtt ttgataaatc ttgatgaatc atatctgcac gaataaattg
    67141 atggtgatca tctgtataaa aggcagcaag tttctcatga agttcttcca tttgttgctg
    67201 tctttttgct tctgctgcta cttcggcttc tactttttga tgatggtcat aataagccca
    67261 gcttcctcca ccgagtagaa gtactgctgc taaaacgaga taaggtactt tttttgattt
    67321 tttcttttgc gctttatctg gatctgtttt ttctaagttt gattcttgat gtgttttttc
    67381 agtatctggc acgattgtta ttgatttcgc ttctgcttca aacagcttag gctggttctc
    67441 ttctttttct atttttgctt caagatcagt accctctttg cttacagatt gattttcagc
    67501 atcggattca ctatttattt catcgggctc tgttgacttt ttgtctgtgt tttcgagtat
    67561 ttcttttttc tctgcttccg gcagtttatt cgttttttcc ttttctaatt gtttttcagt
    67621 aaatacttca gttttttctg tgatatccgt ttttacgtct tttattttta ctgtttcttt
    67681 acctgtggcg ttttctctat cagagtcttt ttcagtttct tgttcctttt ctggctctac
    67741 tttgttttcc tgtgcaattt tttcactgat cattttgagc agctctttcg cgtgctcttc
    67801 ttttgtatct tcacgatgtg ctttgatata agcggatagt atcgaatttt cttcctcatt
    67861 atcgacgatt tctttcagtt cagctactct tcttttttgt tttgattcaa gcgtttcttc
    67921 ttgattcttt cctgattctt ccgaagtctc atgaacagtt gctttcttct gttcattttt
    67981 ctctatatta gttacttgat cgtgagcagg tggttcttcg tcttctggtt ctgctttttc
    68041 gaataattcc attacagatt ctagaggtaa atctttcaat tccgaccatt cgattggatc
    68101 gtttaattct gtatcaggaa agactgcatc ttcagttgat ttatcctgca tagctgcatc
    68161 tgtatttgtt tcttcaattg attcttttat ttgctgatct tctgcagtta tttgatgacc
    68221 gcagtctgga cagatagtat tctgctccat ttttttcgat ccgcaatttg gacatttttt
    68281 catcacttag cgatcggctc ctttactagg tttacgctac catttaatct atcatattct
    68341 atacgtcacg ccaatagctt atttttagga tttacttaaa aataatgaat gaatttcctt
    68401 cctatagaaa aaaaagcttg agactgcgta gtctcaagct ttttttcttt taaaataaac
    68461 caaacagttt tactgatttc tcttctggtc aatagtccac gcttattcta agaaatcttt
    68521 taattgtttt gaacgagaag gatggcgcaa ttttcttaat gctttagcct cgatctgacg
    68581 aatacgttcc cgagtaacac caaatacttt ccctacttct tccaatgttc tcgtccggcc
    68641 atcatctaaa ccaaaacgta agcgaaggac attctcttcc cgatcagtca atgtatctag
    68701 tacatcttcc aattgttctt ttagtaactc ataagctgcg tgttctgctg gacttgttgc
    68761 ttcctggtct tctatgaaat cacctaagtg agagtcatct tcttcaccga ttggcgtttc
    68821 aagggaaaca ggttcttgcg cgattttcaa gatttctcgg actttttctg ttggaagatc
    68881 catttccgca ccgatttctt ctggcgtagg ttctcttcca aggtcttgca gcaattgacg
    68941 ttggatacgt atcaatttat taattgtttc aaccatatga actggaatac ggatcgtacg
    69001 tgcttggtca gcgattgctc gagtgatggc ttgacgaatc caccatgtag cataggttga
    69061 aaacttaaat cctttgcggt agtcaaattt ttcaactgcc ttcatcagtc ccatgtttcc
    69121 ttcttggatc aagtcaagga actgcatgcc tcgtcctaca taacgtttag cgatacttac
    69181 tactaaacga aggtttgctt ctgccagacg ctgtttcgct tcttggtcgc cttcttcgat
    69241 tttcaatgct aacgctactt cttcttccgc agttaaaagg gagacacggc caatttcttt
    69301 cagatacata cgaaccgggt cattgatttt tacaccggtt ggcgcagaaa gatcttctgt
    69361 ttttgcttgt tcagcttttt tctcagcact cttcaagctg tgaattgatg gatcaccatt
    69421 ttcatccacc acactgatac ctgcgtcttc aatcttttgg atcaatttgt ccatttcatc
    69481 tgcattcaaa gtgaatggtg tagcaagctg attggataaa tcatcatata caacttgtcg
    69541 tttgggtttg ttttctttga tgaaagctgc tactgctgct tcatacgttt ttttatctgt
    69601 tccatttgcc ataaaagaag gccccccttg agtagctatt tggcttgttt taactgtttc
    69661 gttaaattga tgatttcaat cgtcaattca agctcaagct gtttgtttcc agttcgtctg
    69721 gcttcttgct gcatttgttt ttttaatgtt atttcatcag ctaagccaga tttgctgatc
    69781 acatctagca agtcttggat ttctcgtggc gaactttctt ctgccaccgg taaatattcg
    69841 atttccacca ccaaccgcct taaattttca tcttgcaaaa agtctaaaaa ctctgcaagg
    69901 ttgaattcat aatgttgtga gacatatgca tcgaataaaa aataaacttc tgcatatgca
    69961 tcatgaataa actgaaattc tcgttctttt aaaatattac ggacagaaac ttctttaaat
    70021 gcacgatata atagaatctg ctctgccttt tctacttgcg tcaaaggtct ctttttccgt
    70081 gcagtttctt gtctcgtaac ctgagtgtgt tgactttcct gaggttcttg acgattttgc
    70141 tgatttgtcc ttcgaagatc gcgcagttgt ttttgtatcg tctctctgcc gatctgaaac
    70201 tctgttgaca gttgagatag atacatatct tgttcgattg gtgaaacaac tcggctaagt
    70261 tcaactagta attcttcgag gtattcgatc ttgtcttttt cattatctaa atttttccct
    70321 tgttttaaat aacgtgattt aaaagtaaag actgtttcgc gcccatgagc cactaattct
    70381 tggaaagatg cttctccata cttacggaga tattcatcag gatcaagctt ttctggaacg
    70441 actacgacag aaagtgctaa tcgactgttt tgccgaagca attcaatccc tcgattggtt
    70501 gcttcaaaac ctgcgttgtc tccgtcatag caaaagacca attctttcgt cagcttttcc
    70561 atttgttgga tctgttgagc tgttagactt gtccccatag aagctaatcc agttttgata
    70621 ccagcctgcc atgcagcaat cacatccata aacccttcga acaacaaaat ttctccgttt
    70681 ttccggatat cgcttcttgc tttatcaaga ttaaataaaa cttgtctttt attgaacagt
    70741 tctgtttctg gactattcaa gtatttgggc tgatcttttt cctgcccttt ttcaggtgca
    70801 agccagcgtc ctgaaaaacc gatcgtctgg ccttgagaat tacgaagtgg aaacatcact
    70861 ctttgataaa aacgatcaga catacggcca tcatcatgcg tgacaaacaa tccagagcgt
    70921 tctaacaatt catttgaaat tgattcattc ttgaatactt gctgaagaaa agaacgctca
    70981 ttaggtgcaa aacctatgtt gaattcttca attaattcta aagacaaccc acgactttgc
    71041 aaatattcta aagctggctg tccagctttt gtatgcaata gcatgtgatg atagatttcc
    71101 gctgcttttt catgagcagc aatcagtttc cccgtagcag attcaggatt ttggacagct
    71161 atagtacgct gacgccattg atcttctaac ggtatctgtt cgaagtctgc cacttttacc
    71221 actgcttctg gaaaacttag accttctagt tcttgaagaa aagtaaacac gtttccgcct
    71281 ttaccacaac caaagcaatg aaaaatctgc ttgtcttctg caacagaaaa agacggtgta
    71341 cgttcttcat gaaaaggaca cagccccaag taatttttac cagacttttt caactggaca
    71401 tattgtccaa tcacctcaac gatattcgtt tgactgcgta ctgtttcgat aacctcttga
    71461 ggaatccgtt gagccatttt ttcaccccct gctctattga tatcttttgg gtttaacaga
    71521 agatatttca ggagaataac cggtaaaaaa tcgcactaac tgaaatcagt gcgattttaa
    71581 aggacacaat tatacatgtt tgattgtatc atatttcatt gctttttcaa gtataacaca
    71641 tttctatctc attaagcatc aatttgctac tcttttcagt aactgatttt gaatatcagc
    71701 cttccagtac aatactcgaa gaacaatatt tacgagcatg aatacaaaga agtatcctac
    71761 gctctctccc aaccctaagt ttacttccaa aattccatgg aacagcattg cagctacata
    71821 tatccctacg atcgtcgtta ctgctaggaa gatgcgcaat gggttgaagg gataacaagc
    71881 ttttacaact gccatgcaac tgatcccaat cagcaagtaa tacatcaaag tagtagtttc
    71941 agcatttccc catgcgaatg tttttccaag tagatacacc gcaatgatat tcactactac
    72001 aagcaaggca tttggtaaag cattaataag tgctgtaggc aaataacggt aagtgatttt
    72061 tcttttatct tgttcaaaag ataaaaagaa ggaaggatac ccttcaatcg ctaaatcaat
    72121 cagcgtgatt tggataggga taaacggaaa tccaattgct gtaacggcac atataatcga
    72181 taaaataaat gaataaatcg ttttgataaa aaagatgcct gagactttcg tcacattgtt
    72241 gaccactcgg cgtccttcaa acaggacttc tggcaatgta gtaaaatcag agtccaacaa
    72301 taccagattc gcaatctgac gtgttgctcc atcaccttct gccatagcaa tgctgcaatc
    72361 tgcttctctt aacgccaaaa catcattcac accgtcgcct gtcattgcaa ccgttctgcc
    72421 gctttctttc aattcattta ccagcaattt cttttgctgc ggactcactc gtccaaaaac
    72481 cgtatagcga tgagcagctt ctcgcacttc catttcttca gtaatttgag aaagatcgac
    72541 atacgcatca taattcggta atcctgcacg tctagcgata ttggagacag taaaaggatt
    72601 gtctccagaa atcactttca gatccacacc ttcctcatga agataagcta gtgtttcttg
    72661 agcgtttttt cggattggat catcgatttc aaacagagca accggctcaa caaatgctgg
    72721 tttttcttcg ttcaattgct gatttggagc gatccccaac ataagtacgc gatagccatt
    72781 cgcttgggct gtttttagac tgtccggaag ccgatcttct tccaccaaac gttcaggcgc
    72841 tcctacgtac acgactccca gttctggaaa ttccatcgcg ccccatttgc gatcagaaga
    72901 aaatgcgact ttgtttgtca catcataccg attagaaagc tcaaaataat ctctcatagc
    72961 ccgcatagtg atgttgttat cactgctttc tgccagatac gtccccataa tttctgggat
    73021 ggctttctcg tacagcggat gtagtgcttc tacccgctgg atactcattt tcccttcagt
    73081 aatggtccct gttttatcca agcataatgt atcgacatgg gccagcgttt caattgaata
    73141 catgtcttga acaaggattc gtttttttgc cagtttggtt acccctgtcg ttaatgcaat
    73201 acttattagc aataccaaac cctttggaag catgcctaac aaagctgctg cagatgcaat
    73261 aacagaaatt ttgatagaag catcgcggat gaacagtgct tccaaaaata gtatgatccc
    73321 caaaggaata atcacgaaac tagtgaattt ggatactttg cgaatcgaat ctacaagttc
    73381 agaacgaata gctttgtgag tctttgcctc gctagtcaag cggacagcat aattatctgc
    73441 acctactcgg ataacttcag ccatgacaga accgcttgtc aaaaagcttc cagaaagcaa
    73501 ttcagctcca gtttctttga caatcaaatc agattcgcct gtcaaaagag cttcatttgc
    73561 ttctgcccgt ccagatataa cctgtaaatc ggctggtatc tgttctcctg ctccgatttt
    73621 taccaaatct cctaatacca gctctttagt agaaatcgat tgttctttac cgtcccggat
    73681 cactagtact tctgattggg aaacaatcga taatttccgt acaagatttc ttgcatgtat
    73741 ttcttgataa attccaataa cgatattgac gacaataatt gctaaatacg ccatgttgga
    73801 atacgcacct acaaataaca gacaaatccc aataccaaag ttcagaaaat tgaataacgt
    73861 caatatatta tcgctgaata tttgttttgt actttttgat gcatcttcct ggtagtcatt
    73921 ttgctggcca gaagccattt tctgaactac ctcttgctgt gtaagtccat tcattttctt
    73981 tttctccatt ttccgccaac tttcaaaaat aatcacgtgt ttaagtctag cgtgttccaa
    74041 gattaaaaac aacttgtttt tataaaattt atagaaaaac acacgaatga ttttacaaaa
    74101 aagatgccaa cctttttgtt tgaatcaccc gtgtgctgtt tttattatca atctatcttt
    74161 acttatattg ttcctccaaa cggctcatcc accaacctag tgctgtaccg gctataaaaa
    74221 gaacaggaca agctagtacc ccagcaactc ccaatcccgc gtaatcggta ggaatgatca
    74281 taatcgttga agcaaaaact acacctaaaa tgaaatggaa tagcttgcta tatgcctttg
    74341 agaaaatgta atccatgatt tttgacaatc caagaacaca aagaatccca ccaattccga
    74401 tcggcacaat cacttcaagt cgtacttctt taaatccgtc agccatcgct ttatacaatc
    74461 ccatatacac caaaaaatta gaagggctca atcctgggac gatcataccc aaaccaatca
    74521 atccgccggc aatcagccat gttccaaaat tctgatcgac ttgcccgtca aataattgag
    74581 cgccgtataa taaaaacaaa taagccagaa caaaagtaac aaccatgatg atcacatcag
    74641 aagtatctct tccttttttc cctgcttctt tccataacgc aggaacagtt ccagcgatac
    74701 atccgacaaa aaaccataat atcgttgttt catacgcacc taataaaaaa ctgactaaaa
    74761 aagaaagtag aaagatgcct gtcactccgc ctagaccaac aggcagaaaa aacaaaacat
    74821 tttctttgaa attttttgta aggtgggcta aaaaagaaat cagccgctca tacatgccaa
    74881 agacagctgc taatgcacca ccgctgactc ctggcaagat aaatcctgaa ccgataaaca
    74941 ttcccttcac aaaccgtaac atccagtctt tggttgtgta ccccacttct tgattttcca
    75001 ttttttgcct tttttccact atttgcgtac tccttctttc atttaatttt attcatgatt
    75061 gaacatttcc tgctatttta cttaaagact ttttcatagg tctctattat tttttcattc
    75121 attttgacaa tatcaggata aaacatgtta cctccattat gatagagata gccgccattg
    75181 taaagcaagg actggatccg ccaatatcgg tattgtttcc cttcctcatt tcctaaaagt
    75241 gggctcagca catctttaga atacgcttct gctaattcta ctgtgttttc tccgccatga
    75301 ttttttacat aggcaatata atctttccca aaattatatg cttggacagc tgtccataaa
    75361 tcgcatcctt gtttctttgc ttctactatc atttccgcca aatatttgac accttgatca
    75421 atactgtcag ctggattatc aatgatctca gcttctccat gcagactttc cgagctctgc
    75481 atgagatctg tcccttttcc ttttgattcg gtcaatatta tcgccttgat caaattctcg
    75541 tagttttcca tatgataatt ttttgcagct gttgttattt ctatttgata gctttccact
    75601 cgttttaccg aacgataagt tcttcctcat aaaaacaaca ccgcaccaat aaccgtcaga
    75661 atgatcatgt aaaaaagaat acggataata gataatcgtt ttcgcttcat ttcatcacct
    75721 agttattttg acatcttttt ttatcttact atttctttat cttcttggct atttcttcct
    75781 tgatttctgt gtacgcctta agaaaaaatg aattttcctg tattttttga catcttacga
    75841 aaatgatcgt tgtttttcag taaaaacaat tgcccaatga ctgatataat cgttatactt
    75901 tacacagtag gtgattatgt gaaaaaagaa aagaaatatg caaaaatgcc agatgggagc
    75961 gaaatttact atgaaaagag cggtcaaggc ttccctctct ttttactgca tggcaatgac
    76021 ggcagcggcc gctttttttc agaacaggtc cctgtactcg aacgctacta taccgtgtat
    76081 ctagtagata gccgaggaca tggtcgttcg acaaacgaag catctatgtt gaattttcag
    76141 ttaatggccg aggatctgaa tacgatcatg ttgctggaaa aaatcgatca ggcagatttt
    76201 cttggattta gtgatggagc aaatctagca ctggtatttg ccagcagctt ccctaaaaaa
    76261 gttcatcgat tgattttaaa ttctggaaac acgcttgtta aaggcgttcg tttttctgcc
    76321 agagtcatca gtaatattca ttatgcatgg gtatggttac tctctttatt tcgcccaagt
    76381 cttcgcaaaa atcttttagt tatcaaactt ttgctgcatg acatcgggct tacagaaaat
    76441 gatttaaaaa aaatcaactc ccccactttg atcatcgtgg gaaaaaaaga tgtaatcaag
    76501 ctaaaacatt ctttgtatat agctaaaact ataccaaaag cttcctttgt gcttgtgaaa
    76561 gaacaaggac atgaattagc tagaaaagat cctgaacgct tcaatcgaga agttcttcaa
    76621 tttctttctg aaacataact attaggaata gaaggtgatt tatttgttaa aaaataccat
    76681 acaatggctg aaaaaccacc taggactgtt caaaacaatc tttttgattt ctgtcattgt
    76741 cattattgtc ggtgaattga tgtccatcgg taaaactcta tctatccagc aattaggaga
    76801 aacgtttgcc actatacctg tatggaaaag cggactaatg ctattgattg gtcttatctc
    76861 tgtgttacct atggttggtt atgatattat tttgaatcgg atgcttgaac aaaagcagaa
    76921 tcctcgttac ctgtttgaga caagctggct gatcaatacg atcaacaata ttgccggttt
    76981 cggcgggttt gttagtgtgg ggcttcgctc tgaactatat ggacaaaaga aagagagcag
    77041 aaacgtgatc caagcattat cgaaagtttt cttgtttttg atggctggac tttctattta
    77101 cagtctgctt tcttttttac ttgtagtctt cacgccagtt gctccttttt tgaagcaata
    77161 ttggatatgg ttgatcggcg gcggtctata ttttcctgtc gtctttttat ttactacttt
    77221 caaaaagaaa ggattccttg gtggtacctc acttaaaact caaggacagc tattgctagt
    77281 ttcattgttg gaatggaccg gtgtcctgtt tagtttcctt tctgttggtt atttaatgga
    77341 aatccggatt gatctgtggc aaacaattcc attattcatt gctgcttcag tgataggaat
    77401 cgtgtctatg attccaggag aaattgggag tttcgatgta atgatgatta tcgggttgtc
    77461 cgctattggt gtgccaagag aaatagtcgt tgtgtggatc ttgctctatc gcctgttcta
    77521 ctacatcatt ccgtttttga ttggaatcgt ctttttcttc aaaaatatcg gttccacttt
    77581 tgatcagcgt tattctggta tccctaaaca attagcaaca gaaattgcgc ataaaatcgt
    77641 ggttgtctta ttatactttt ctggaatcat gctagtactt tctgccacta tcccgcaagc
    77701 ttttacagag tttcgctggc ttcatagttt gaacccattg aaatttcatt ttattatcca
    77761 atttcctagt atactattgg gatttctttt aatcattatg ggcagaggga tcgcagcacg
    77821 tgtgaaacga gcatatttgc ctacaatctt cttgattgtt ctagctttac tttatgtttt
    77881 attaagtgat tttagtttca caccggtggt tttcttgtct attctgcttc tgatcattct
    77941 tgcttctaaa aacgaattat ttcgggaaca attgatctat tcatgggagt ggcgtacgat
    78001 cgatggaatc attattggtg cactgtcctt gctttacatc gttattgggg tatacaatct
    78061 gccggatttc cctcatcggc gtcaccattt tatttccttt ttcttatttc cttctgaaaa
    78121 gatttggttt tcgggattgt tggccatcat cgctgttagt ttcatgatcg ttctatttgt
    78181 tcatttcctt caaggagaaa agaaacagat tggcgaagcc tttaatgaag aaaaggccct
    78241 gaagatcctt acaacttatg gaggaaactc cgatagtcaa ttgatcttct taaaagataa
    78301 gcggatgttt gcctatgaaa aagacggtga accaactgtt cttctccaat tcgcttgctt
    78361 caataataaa tgtattgtaa tgggtgatcc ttctggtaag aaagaagatt ttccagaagc
    78421 aatcgaagct tttatcgaag aaacagatcg actatgctat ttaccagttt tctacgaaac
    78481 aagcgaagag attgttatga ttttgcatga attcggctac gatttcatta agatggggga
    78541 agaagcttat gtagacctga atagttttac aacttcaggg aaaaaaatga agggcactcg
    78601 tgctgtcttg aatcggatcg aacgagaagg atttacattt gatgtcttac aaccaccatt
    78661 ttctactgag caaatgagta ctttcaaaaa tatctctgat aattggttgg gttcacgaaa
    78721 ggaaaaaggg ttttctttag gctttttctc tgaagattat ctacaaagag cgcctattgc
    78781 agttgtcaaa aatacccaag aagaaattgt cgcttttgca acgatcatgc ctacttacac
    78841 gaacaataaa gtaggaacga ttgatctgat gcgatatgat tctaaaaaag caccttctgg
    78901 cagtatggat ttcttgttct tgcatttgtt tgcctatatg aaagaagaac atatccaatg
    78961 gttcaattta gggatggccc ctctttcaaa tgtcggaact tccagaaaga gttttttaca
    79021 ggaaaggatt gcatacttgg tttacgagtt tggttctcat ttttattctt tccatggatt
    79081 aagagaatat aaaagcaagt acgctacaaa ctgggtctca cgttatactc tatattctag
    79141 agatagttgg attgcatatg ttatgattgc tttgctgatt attgataatg cgccagttga
    79201 gcagacacaa ggtagaataa gtggtttgaa aaaatggata cgaagaaagt attaaaaact
    79261 gcataccgat agatgaacac tctcatgatg aataaaagag actgaagtaa aacgaaagtt
    79321 catgcttcta caatctcttc ttatacaatt gaagaacaaa gagcggtcca aacagaaatc
    79381 ctgtttggac cgctctttta ttttaaacat ttttcattac caaaatattc gagtcgcgtt
    79441 tcttatgctt cgatctctgt aacgatacct gaacctactg tccgtccgcc ttcacgaatt
    79501 gagaatgtcg ttccgttttc aacagcgatt ggatggatca agtcaacatc aatcgtcacg
    79561 ttgtcaccag gcatgaccat ttctgtatct tctggcaatg tgattgttcc tgtaacatca
    79621 gttgtgcgga agtagaactg tggacgatag ttgttgaaga atggagtatg acgtccacct
    79681 tcttcttttg tcaacacgta cacttctgct ttgaattttg tatgtggagt aatggaacct
    79741 ggtttagcaa gtacttgtcc acgttcgata tcgtcacgtt ggatcccccg taacaacacg
    79801 cctacgttat ccccagcttc cccgtaatct aacgttttac ggaacatttc tacacctgtt
    79861 acaactgctt tttgtgtttc aggtttgatc cctacgatct ctacctcatc accgacacga
    79921 acagcaccac gatcaatacg acctgaggca acagttcctc gacctgtaat tgagaagacg
    79981 tcttccactg gcaatagtaa tggtttatct gtatcacgtt ctggtgttgg gatatattca
    80041 tctactgtat ccatcaattc cataatagca gcttcagcat ctggatcgcc ttgcaatgct
    80101 tttaatgcgg aacctttgat cacaggagtg tcatcgcctg ggaaaccata ttcgctcaat
    80161 aactcgcgaa cttccatttc taccaaatcg atcaattctt catcatcgac taaatcaact
    80221 ttgttcaaga aaacaatcag gtattttaca ccaacttggc gtgacaataa aatgtgttca
    80281 cgtgtttgag gcatcggacc gtcagttgca gaaacaacta agattgcacc atccatttgt
    80341 gctgcccctg taatcatgtt tttcacatag tccgcgtgtc ctggtgcatc aatatgcgcg
    80401 tagtggcgtt tttctgtttc atattctacg tgtgcggtat tgatcgtaat cccacgttca
    80461 cgttcttctg gagctgcatc aatactagca tagtcttgag gatttgctag gccttttttg
    80521 cctaatactg tagtgatcgc agcagttaaa gtagttttcc catggtcaac gtgtccaatc
    80581 gtaccaatgt taacgtgtgg tttacttctg tcataatgtt cttttgccat aatttacaaa
    80641 cctcctaaat aatatagatc actgaaaaat ttcagctctc acctttttat tatagtcttt
    80701 ttttgactaa atcaaaaaga atacgtccga cttacttttt gtaagattcg aactaagctt
    80761 attatacgtc aatattggtc aaagtcaact aagagcactc gtctgtctta tacgcgaaaa
    80821 aagtaccttt tataaataaa aaaatgtgtt ttttgagaaa aacttcaaga tagtccttaa
    80881 ctttcttttg aagcaataag aacaaaatga ggaaaagttt aaaattcagc tgttgccaac
    80941 aactttcaat agacgaaatc ttctatttcg ttaataataa ggaaagaggt gaagtacatg
    81001 aaaaaattaa ttggcgtact tgtcgtttta ggcatatttc tcggcggaag ttttgcagct
    81061 tatcattatt tttacggcgg cgaagcttat tatacaaaaa tcacgacgaa tggcgaaatg
    81121 tcagctaccc aagcagataa cggagagaaa ttcacgactt atacctacaa gcaagcggct
    81181 tataataaag atggtgaaaa aaaacaggtg acgcttcgcg aagaaagaga acatccatta
    81241 aagatgaatg cgtatcttaa actcaaagtc aatcctcgta aaggtgtatt aagctgggaa
    81301 gaaataaagg cttctgaagt gcctaaaaat gcggcagaaa aaatcgataa ttagtaaatg
    81361 gtcttaaaat tttattagat aaaa
//
LOCUS       DAFLVO010000004        64885 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.004, whole genome shotgun sequence.
ACCESSION   DAFLVO010000004 DAFLVO010000000
VERSION     DAFLVO010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 64885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64885
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.004"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..1420)
                     /locus_tag="L1U99_000288"
     CDS             complement(<1..1420)
                     /locus_tag="L1U99_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBN1210864.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAG"
     gene            1672..2853
                     /locus_tag="L1U99_000289"
     CDS             1672..2853
                     /locus_tag="L1U99_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBN1210865.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(2913..4541)
                     /gene="treC"
                     /locus_tag="L1U99_000290"
     CDS             complement(2913..4541)
                     /gene="treC"
                     /locus_tag="L1U99_000290"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBN1210866.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(4992..7703)
                     /locus_tag="L1U99_000291"
     CDS             complement(4992..7703)
                     /locus_tag="L1U99_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1210867.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(7713..8414)
                     /locus_tag="L1U99_000292"
     CDS             complement(7713..8414)
                     /locus_tag="L1U99_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1210868.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            8600..9199
                     /locus_tag="L1U99_000293"
     CDS             8600..9199
                     /locus_tag="L1U99_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBN1210869.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            9280..10293
                     /locus_tag="L1U99_000294"
     CDS             9280..10293
                     /locus_tag="L1U99_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBN1210870.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            10401..11318
                     /gene="rbsK"
                     /locus_tag="L1U99_000295"
     CDS             10401..11318
                     /gene="rbsK"
                     /locus_tag="L1U99_000295"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBN1210871.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            11346..11741
                     /gene="rbsD"
                     /locus_tag="L1U99_000296"
     CDS             11346..11741
                     /gene="rbsD"
                     /locus_tag="L1U99_000296"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HBN1210872.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            11741..13114
                     /locus_tag="L1U99_000297"
     CDS             11741..13114
                     /locus_tag="L1U99_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1210873.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            13471..15615
                     /locus_tag="L1U99_000298"
     CDS             13471..15615
                     /locus_tag="L1U99_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBN1210874.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLRLDKSFWLDLPLKK"
     gene            complement(15667..16707)
                     /locus_tag="L1U99_000299"
     CDS             complement(15667..16707)
                     /locus_tag="L1U99_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBN1210875.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(16984..18786)
                     /locus_tag="L1U99_000300"
     CDS             complement(16984..18786)
                     /locus_tag="L1U99_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1210876.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(18800..19552)
                     /locus_tag="L1U99_000301"
     CDS             complement(18800..19552)
                     /locus_tag="L1U99_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1210877.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(19561..19923)
                     /locus_tag="L1U99_000302"
     CDS             complement(19561..19923)
                     /locus_tag="L1U99_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBN1210878.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(20099..20971)
                     /locus_tag="L1U99_000303"
     CDS             complement(20099..20971)
                     /locus_tag="L1U99_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBN1210879.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(21022..21510)
                     /locus_tag="L1U99_000304"
     CDS             complement(21022..21510)
                     /locus_tag="L1U99_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBN1210880.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(21648..22439)
                     /locus_tag="L1U99_000305"
     CDS             complement(21648..22439)
                     /locus_tag="L1U99_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBN1210881.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(22494..23102)
                     /locus_tag="L1U99_000306"
     CDS             complement(22494..23102)
                     /locus_tag="L1U99_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBN1210882.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(23095..23412)
                     /locus_tag="L1U99_000307"
     CDS             complement(23095..23412)
                     /locus_tag="L1U99_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBN1210883.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(23568..24296)
                     /locus_tag="L1U99_000308"
     CDS             complement(23568..24296)
                     /locus_tag="L1U99_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBN1210884.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            24455..25336
                     /locus_tag="L1U99_000309"
     CDS             24455..25336
                     /locus_tag="L1U99_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1210885.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(25573..26616)
                     /locus_tag="L1U99_000310"
     CDS             complement(25573..26616)
                     /locus_tag="L1U99_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1210886.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(26619..27287)
                     /locus_tag="L1U99_000311"
     CDS             complement(26619..27287)
                     /locus_tag="L1U99_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1210887.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            27429..29765
                     /locus_tag="L1U99_000312"
     CDS             27429..29765
                     /locus_tag="L1U99_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1210888.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(29880..30191)
                     /locus_tag="L1U99_000313"
     CDS             complement(29880..30191)
                     /locus_tag="L1U99_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210889.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            30372..31847
                     /locus_tag="L1U99_000314"
     CDS             30372..31847
                     /locus_tag="L1U99_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBN1210890.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            31894..32478
                     /locus_tag="L1U99_000315"
     CDS             31894..32478
                     /locus_tag="L1U99_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HBN1210891.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            32480..32863
                     /locus_tag="L1U99_000316"
     CDS             32480..32863
                     /locus_tag="L1U99_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HBN1210892.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(33180..33464)
                     /locus_tag="L1U99_000317"
     CDS             complement(33180..33464)
                     /locus_tag="L1U99_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HBN1210893.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(33816..34526)
                     /locus_tag="L1U99_000318"
     CDS             complement(33816..34526)
                     /locus_tag="L1U99_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HBN1210894.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(34523..35995)
                     /locus_tag="L1U99_000319"
     CDS             complement(34523..35995)
                     /locus_tag="L1U99_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBN1210895.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            36133..36606
                     /locus_tag="L1U99_000320"
     CDS             36133..36606
                     /locus_tag="L1U99_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBN1210896.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(36759..37310)
                     /locus_tag="L1U99_000321"
     CDS             complement(36759..37310)
                     /locus_tag="L1U99_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBN1210897.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            37415..37945
                     /locus_tag="L1U99_000322"
     CDS             37415..37945
                     /locus_tag="L1U99_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HBN1210898.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(38428..38871)
                     /locus_tag="L1U99_000323"
     CDS             complement(38428..38871)
                     /locus_tag="L1U99_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1210899.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(38887..40047)
                     /locus_tag="L1U99_000324"
     CDS             complement(38887..40047)
                     /locus_tag="L1U99_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBN1210900.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            40554..42254
                     /locus_tag="L1U99_000325"
     CDS             40554..42254
                     /locus_tag="L1U99_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210901.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(42356..43189)
                     /locus_tag="L1U99_000326"
     CDS             complement(42356..43189)
                     /locus_tag="L1U99_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBN1210902.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(43493..45658)
                     /locus_tag="L1U99_000327"
     CDS             complement(43493..45658)
                     /locus_tag="L1U99_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1210903.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVAFILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            45918..48212
                     /locus_tag="L1U99_000328"
     CDS             45918..48212
                     /locus_tag="L1U99_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBN1210904.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            48205..48870
                     /gene="pgmB"
                     /locus_tag="L1U99_000329"
     CDS             48205..48870
                     /gene="pgmB"
                     /locus_tag="L1U99_000329"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBN1210905.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            48863..49870
                     /locus_tag="L1U99_000330"
     CDS             48863..49870
                     /locus_tag="L1U99_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBN1210906.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            49892..50911
                     /locus_tag="L1U99_000331"
     CDS             49892..50911
                     /locus_tag="L1U99_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1210907.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(51192..52559)
                     /gene="nhaC"
                     /locus_tag="L1U99_000332"
     CDS             complement(51192..52559)
                     /gene="nhaC"
                     /locus_tag="L1U99_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBN1210908.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(52668..54089)
                     /locus_tag="L1U99_000333"
     CDS             complement(52668..54089)
                     /locus_tag="L1U99_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1210909.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(54332..56209)
                     /gene="tdc"
                     /locus_tag="L1U99_000334"
     CDS             complement(54332..56209)
                     /gene="tdc"
                     /locus_tag="L1U99_000334"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBN1210910.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(56500..57756)
                     /locus_tag="L1U99_000335"
     CDS             complement(56500..57756)
                     /locus_tag="L1U99_000335"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBN1210911.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(57868..58073)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            58336..59637
                     /locus_tag="L1U99_000336"
     CDS             58336..59637
                     /locus_tag="L1U99_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBN1210912.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(59706..60305)
                     /locus_tag="L1U99_000337"
     CDS             complement(59706..60305)
                     /locus_tag="L1U99_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1210913.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            60559..61440
                     /locus_tag="L1U99_000338"
     CDS             60559..61440
                     /locus_tag="L1U99_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1210914.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            61453..63063
                     /locus_tag="L1U99_000339"
     CDS             61453..63063
                     /locus_tag="L1U99_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HBN1210915.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(63140..63799)
                     /locus_tag="L1U99_000340"
     CDS             complement(63140..63799)
                     /locus_tag="L1U99_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBN1210916.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVALYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(64082..64747)
                     /locus_tag="L1U99_000341"
     CDS             complement(64082..64747)
                     /locus_tag="L1U99_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HBN1210917.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
BASE COUNT        19458 a        13217 c        11704 g        20506 t
ORIGIN      
        1 ttcctgcata taaatgaaaa tgttcggagt cagccggtgc aatcgtgtga tcactgaatt
       61 gaatatatct aaaagcgcca ctttccttat cttctgcttc gaatagatac cttacgccac
      121 ggtttcctgc ctcgtaggtc aagatttctt tccctacata acgataattt gaacgtttcg
      181 ttgttccatt cttaaacgta aatgccatct ctttctcact gatcttgatt gaagcaatat
      241 ctgtttgata gcccttcgta taatattctt tatattcttg tgctgtctta tcctgattca
      301 atttttcttt atattcaaaa acaggatcaa aagtcccatc ttctacatac gtatctactg
      361 tttgccaagt tcctgcccaa tctgaaagag agcgatcttg tacatcctcg tcttcaaaat
      421 aaccgttgta gacgctcttt tcttttttgg gggtcaaagt atcttctagc gggttttctg
      481 tctctgtcgt ttttttcaac gcttcgaggt ttgcttccat gatagaaaga tagttttctc
      541 cattttctat ttgttcattc gtcaatcctt ccaaaggatt caatacttct aaagatacac
      601 ctgcttcgtt tgctaacgtt ctggcaatac tatctttggc gttttcttca aaataaatat
      661 agttgattcc atgttcttta acaaagtgtt tcagttcagc aattctcgcc gcagacggtt
      721 cttcactaga agaaagacca gcaatcgata cttgattcaa tccatattct aacgctagat
      781 agttgaatgc agcatgttgc gtgacaaaag atctttgttt tgcttgctta aaggtttctt
      841 gataaagctg atggagtgct tgaagtttct cggtataggc tgctgcattt tttgtccata
      901 cttcctgttt ttctgggtaa gcttcaatca gctgatcacg tatgtttgct acctgcttga
      961 ttgctaaact tggagctagc catacatgtg ggtctagctc atgtgtatgg ccttcttccc
     1021 cgtgttcatg gtcatgatca tgtccttctt cacttcccgg aagtaaaagc ataccttctg
     1081 tcgcttttat cgtatggaca ttgccttctt gtaatgtttt ttggattgcg gggacccatg
     1141 tttccatgtt ttcatcatta taaacaaaga tatctgtatc ttggatcttt gccatgtctt
     1201 tagcagaagg ttcataatcg tgggaatcag tccctgctgg aatcaataac tctacttctc
     1261 cttcatcccc gacgattgct tttgtaaaat catacatggg ataaaaggtc gtcatcacgc
     1321 tcaatttttc tttactgtcc tcggctttcc cacttgcccc gcaagcagtt aacatacctg
     1381 ctaaaaccag catggccaat atacctatca atcgtttcat ttatgacact cctcttctca
     1441 tcttctttca tttgaatgtt ccgattcgct tttcgcaaac cgtaatagtt acgttttagc
     1501 aacaggattt aatttatcat atggttaaaa gaactgtcaa gcgttttctt attttaattg
     1561 atgagaaagt ttatatgaat gattgacgat atttttgcaa tcaacctcta tcattttcct
     1621 tttatacccg cttttgtcta taatgaagtt atagataaag gaggaaaaag agtgaaaaaa
     1681 gaaacagata caacgaatcg tttgatccgc tttttaggag gaaaaacctc ttactatgtt
     1741 ttaggaatag ttatcttact tgcgctgatc atttattttt tccatcagat ctcgtttata
     1801 ttcaagcctg tcggaatcat tatcgctact atcttgcccc cattattgtt tgcactgatc
     1861 ttgtattatc ttttggaacc agtcatcaaa cgtttgagca agcacctttc gaggaacttg
     1921 tcagtcatta tcgtttatgt gattatttta tttttattgg ggcttggaag catatggctt
     1981 attccttttc ttgaagaaca ggcaaagaca ttgatcagta gtttgccaga tttgtttcaa
     2041 gattttcaag agagtctccg acaatttttg gagaaaacac cttttgccga ttcatttaat
     2101 caatttttcg cttctattga cgacgtgacg tctgatatag ctggatttat tggaaattat
     2161 tgggaaagtg gcgcacaacg gatcagcaac attttttcaa ctgttacagc tatttttatt
     2221 actttattta ctggtccaat tgtcgctttt ttccttttga gagatcctca aaaattttat
     2281 cagtcagttt tagcgattgt cccaccagca tttcgtacag attttaaaaa tttgacaaag
     2341 attgctaatc aacaattggg ttcatttcta aaggggcaaa tcattgcttc atttatcctt
     2401 ggagcagtct actgggtttg tttcttactg atcggattag aatttgctag tgttttagct
     2461 atttctgctg ggttgttatg tatcattcca tatattgggc cgtttatcgc cttctttcca
     2521 ggtttgatca ttgcattcca agactctact tttatggctg tcaaatttgt cattgtctgg
     2581 tttgccgtac aacttctcca cggtgacttg gtgattcctc gagtaatggg tgatcgttta
     2641 cagatccatc cgattacgat cttaatcgtt ttacttgtca tgggtgatct aatgggaatt
     2701 gtgggcgtta tttttggtat tcctatctat acgttagtca aattactcgt tacttttatt
     2761 ttccgtaaat tcaaacaacg ctacaataaa ttttatggcg ataaaggaga gtatgaaaac
     2821 tcttcatttt ctgaagaaga ttattttaaa taaaacacaa aacgtcgatc ttacgagaat
     2881 agctcgtagg aacgacgttt tgtgtttttg ttttaatttt tcagcaaagc aattgcctgg
     2941 tatggtttta gctccagact ttgatgaaga acagtatcgg aataattatc gataagaata
     3001 ttggcttctg tgaatccttc tgggatggcg atccttgtat ctttatcata gaaatttgtt
     3061 aatacaagca gctgctgtcc ttcaaattgg cgaagaaagc cataaacttc cggatgattt
     3121 gcttcataag catgataatc tccttgtgca acgattggat atgtttttct cagccgaatc
     3181 aatttcttgt aataggacaa aatagaatct tcagaagata gttctttttc tacattaatc
     3241 tcttctagct tgcctccaac ttttaaccaa ggtttccctg tagtaaatcc tgcttgttct
     3301 gtgtctgacc attgcatggg tgttcgagag ttatcgcgag attttgcttt gatccgacga
     3361 aacgcttctt tttctgtgaa tccttgttca aggagtaact tataagcatt caaactttct
     3421 acgtcaatat agtcggaaat cgatgaatag tctgggtcga tcatgccgat ttcttctccc
     3481 atataaatat agggcgtccc acggttcaaa tggatcatgg ttgctagcat ctctgctcct
     3541 tgttttcgat actgatcgat agctacaaat cgattgagcg cacgtggctg atcatgatta
     3601 ttaaaaaata gagcattcca gccgttaccc tcactcatct tttctcccca tgtatgaaat
     3661 agtcgcttta attctgcaaa atcaaatgga ggagtagacc atttattccc attttcataa
     3721 tcgactttca aatgatggaa attaaagacc attgataatt cttctctact aggttctgta
     3781 tacaagatac aattttcgat cgtcgtagag ctcatttcac cgactgtgat gatagtggaa
     3841 tccgtcccaa acgttgcttg gttcaattct tttagatacg tatgggtgat tggtttgtcc
     3901 gtatattcag gtttgccatc attttcttta ttatttttca attgttcgtc tttaccgata
     3961 acattgataa catcgaaacg gaatcctttt accccttttt ccatccaaaa acgaacaact
     4021 ttgaatagtt cctctcttac tgcttggttc cgccagttca agtcagcttg tgtccgatca
     4081 tataagtgca aataatattt ccccgtatct ccaaatggcg accaagcact tccaccaaat
     4141 tttgataccc aatccgttgg ctcttctctt aaaatgaaga agtcctgata atgctggtcc
     4201 cctgctagtg cttttttgaa ccattcatgt tctgtcgaaa cgtgattcag caccatatcg
     4261 agcatgattt ctatccggta tttctttgct tcggctatta gctgttcgaa ttcctccatc
     4321 gtaccaaaga taggatcgat ggctgtgtaa tcagagatat cataaccgtt gtctttttga
     4381 gggcttggat aaatagggtt tagccaaatc atgtcgatgc ctagatcatt cagatacggg
     4441 agtttttctt tgattccttt taaatctcca attccatcac cattactgtc tttgtaagat
     4501 ttgggataga tttggtaaat gactttgtct ttaaatgtca tggatattta cctccattca
     4561 actgatttat tacctaccac aacttatata tacaagttat catttattat tataactgaa
     4621 ccgaaagcgt ttgtaaaatt tatctttata cattctaaga ggtctgttgc ccaataaaaa
     4681 acaagagatc agacatgtat ttgtctatcc tcttgtttaa aatagcaaaa tattcttgtt
     4741 tcttctataa atggtgttca aaagctttta tctacggcaa tcagtcttct caaatgtaaa
     4801 acatgaggag ctaattttat ttgagtattc tttttgctcg atgcaggacg gcttttttac
     4861 aacctctgat tcatggtgtt caatcagctg tccttcggta ttagctcaaa aaacggcaaa
     4921 atatgaaaaa ctattttgcc gtttgtttct ctaatactca ggtcaaaccg ctgatttcac
     4981 aacctctgtt tttattcatt cgatttcaac gcatcaatca tatcgatatg ctttaatttg
     5041 aaatgggtaa caatcatcac aataaccgta aatacgatag ttaatcctgc tgataagaca
     5101 taagcccacc atgtgatcac taatggaaag atgacattct ccatagacgc ttgttgcaag
     5161 atgaagtcag tcaatatata tcctacacca aatcctccga tgattcctaa aagagtaaag
     5221 atgatatttt ctcgaacaat gtacatcgtg acttctttat caaaaaatcc aaggactttt
     5281 attgtagata attcgcgtac acgctcggaa atattgatat tagttagatt atacaagacg
     5341 ataaaagcca gcagtcctga taatacgaca aagattaaga caaccgagtc taagttcgcc
     5401 attgattctt cttgcgtttc gatttgtttg gacatgaaag acgtatttgt cacagcgtct
     5461 gtggcaagca gtttctcgga aagcatttct tcttcttttg ttgtcatctt atctgtacgc
     5521 agcaaaaatg cattatccat catcgattga tcagtaactg aagcataata ttcaggggac
     5581 atataaataa agctacctag atagtttttc acgatttctt ttacttcgac tttccattct
     5641 ttttgatctt catcataaag cgaaatatga tctcctgtag ataagtcaaa tagttctgct
     5701 actttttgcg taatagcgat tcctgtttta ggcaaggagc gtgggttctc ttcaagatca
     5761 gttaaatgga taaaacgatc caaatcagct gttttacttg gtacgatcac tgtcagactt
     5821 tgcgaagcat gtcctttttt tctcaattct acggtttgag tatgaatagc taggatctca
     5881 tttacttttt cttgcttctg cagcatatcc gctgcttttt gacgactatc ttccgtggat
     5941 gaatccaatg taacgattgc ttgatagtca atgatcggtc caaattgttt ggctgaaaca
     6001 gaacttagag aatctttcaa tcccacgcct gcaaccatca gcccggcaca tccagcaatt
     6061 ccgataatcg ccataagcat tcttgactta tatcggaaga gatttcggta actgattttt
     6121 tgattaaagc taaggcgtga ccacagcgga gtgatgtatt caagaaaaat gcgtttccct
     6181 ggcttcggtg ctttcggttg aagcaatgca gcaggccgtt ctcttaaatc tttgaataaa
     6241 acgatcattg cagcgccaaa tgcggcaatg aagaatgcgg cagctgcttg taaaatcggc
     6301 ggccagtcat aaaaaataag cgcactccca atatcatacc gctcgttaga cagctcaaaa
     6361 atgatccttg gcaaaagatt cgttcctaat atcgttccta aaacaatacc tatccctgag
     6421 gctagacttg catagattgc atattttttt gcgatttcaa ctttcgtata acctaacgcc
     6481 tttaatgtcc cgatttccct gcggttttct tctaccatac gtgtcattgt cgtaaaggtg
     6541 atcaatgcgg caataaagaa aaagaaaaca ggaaaaacat tggcaatcgc agcgatacga
     6601 tcagacagat caccaaattc ttgaaaaccg acattttctg aacgttcatt gtataggtat
     6661 gatggtttag ttaaattttc aattttttct gcatttcgat tcaattcttc ctctgcagag
     6721 gccagttcac gttctttctc aactaattgc ctttcttgtt cagcaagttg agcttcttgt
     6781 tgagataatg tttgaacagc gattgttcgt tgcgcttcag gaagctgctg gatagttgct
     6841 gactgttgcg ctaactgttt tttagcatct tctaaccgtg ttcttgcttg cgttgtttgt
     6901 gctttgccat ccgctatttt ttgctgtgcc ggttctaatt cttcgttggc cgattttttc
     6961 agctcttcta agcgttcttc gggtcgatct tgtaaatact tttctgcctt ttcttgattt
     7021 tgctccattt tatctttgta agctttgctg tacgtattca aattctttac gtttgtaaaa
     7081 tcaagatata agacagaata aatatctgtt ttaaaaacgg attcaggtaa atagacaaaa
     7141 taatcgacgc taccatttcc gacgttcgcg tatcctctct ccaaattgtt gatgaacaat
     7201 ggagaacgga caaagcccgt gatggtatac tctttttctt tcaattcatc tgaatcaatc
     7261 tgataaatat caccgatttt atacccttca tcttccgctt tttcatccaa tacaagctgg
     7321 tttggttttt ccgggagttt tccatcagtt aattgtagct tgttctgctt gttatttttg
     7381 ttataagaaa atatttgaat cacttcgttt ttgccagtat tggaataata gatctgtttt
     7441 cctgtttcta cttttgcatc tgggatcttt tctgcttgag caatatcttt ttgtgtcaag
     7501 ccaccagtag aaacgatttg caaatcagaa agtcctgctg taccaacata gtgatccatc
     7561 gttttttgca tgacaggtcc agcagttttg acacctacaa ataaaagtgt tcctagcatg
     7621 acaataagga tgattgcaat gaatcgtcct ttagattgcc gaatttcgcg aaaacctgct
     7681 ttaagatatg ttcttgtttt cataaaatcc ccctaccata caatctcatc aatggatgaa
     7741 ggatgatcat ttaattcaac agaccttact ttagcatcat taatgtgaat gactctatca
     7801 gcgatgggcg ctaaagcaga attatgtgta atgatcaaaa cggtattgcc gtgttgtctg
     7861 ctagcgtttt gcaataattt caatacttgc ttgcccgttt caaaatccag cgcgcctgtc
     7921 ggttcatcac ataaaagaag tttgggattt ttagctagtg cacgagcaat tgaaaccctc
     7981 tgctgttcgc ctcctgataa ttgggacgga aagttattca atcgatgagc taggcccact
     8041 tgcctcaata cctctacagg atcaagcgca tcaggagaaa cttccgttgc caattccaca
     8101 ttttcttttg ctgttagatt aggaacgaga ttgtagaatt ggaaaacgaa ccctacatct
     8161 gttcgtcggt aagcagtaag ctgtttatct gaaaattgcg caatatctgt gtcatcaata
     8221 atgatctgac cttcatcagg tgtatccatc ccacctaaaa tattaagaat cgttgacttt
     8281 cctgctccac ttggaccaag tataatcact aattcgcctt tttcaattga aaaagaaata
     8341 tcgtcatttg ctgtaatggt cgtttctccc attttgtatc gtttgtattc attttttact
     8401 tcgacatact tcactctgat tcctccattt tcacgatatt tctcgctata tctatgcatc
     8461 gaatgcgttt tctcacactt atttatttta ccactgaatt tctctagact aaagaaagga
     8521 atcctttaat ttagttgaca aataaacgat ttatgattta cttacataaa aaacattgtt
     8581 atttgaaaga aggaacatca tgaatgattt aaaggaaaat atgatttttg atttatcaaa
     8641 aactgctttt gtcgcgatcg acatgcaaaa agagatcgta aataacggta cactctctcc
     8701 acacactgca gcatctattc tgacaaacaa tgatttgtta gtaagaacat tgaaacgtac
     8761 cgctgccttg aaagttttag tgaacgtaga catctccact ttcccttatt tgagtcaaca
     8821 aactgatatg ggtggaatga ctgcttctgt acctccagaa ttcactgatt tacttttgaa
     8881 ggattctttg aaagatacag ataatatgtt gactatcaca aaatacaatc caagtgcttt
     8941 ttttggtact tctcttgatc ttcaacttcg ccggcgtgga atcgaaacta tcattttaag
     9001 cggtgtagcg acaacaaacg gtgtatatgc tactgcatta gatgcctttc aacacgggta
     9061 ccatatcgtg cttgctgaag atgcttgcag tgatcgtgac aaagaatccc atcaattgtt
     9121 cataaaaaag atatttccga aaactgcacg agtacgctca acgaaacaaa taatcgaagc
     9181 tatccaacaa agcaaataag tactggcaca cgtgattttc atttacttct ttttgatttc
     9241 atgggaaaat aaccacagga tttagatagg agtatgaaca tggtgaaaaa aaagatcaca
     9301 atcaaagaag tcgctaaact ttccggcgtt tcaatcacaa ctgtctcctt gatattaaat
     9361 ggaaatacgg agaaattcag tccgaaaact gttcagaaag ttttagctgc caaagaagaa
     9421 ttaggctatc agcctgacta ttttgctaga caaatgatta ccaaggaaac gaaaacaatt
     9481 ggtgtactcg ttcctgatat cacgaatcca ttcttcagta cactgatgcg aggaattgag
     9541 gatatcttgt ataagcagaa tttcgtcacg atattatgta atgctgattc tgatcatcaa
     9601 aaagaaatcg aatatctagc cgagctcaca cgtcgaggtg tggatggatt cattatcgcg
     9661 acttctgctg tctctacaga tgcaatcaac gaaaatttga aaaaacaagg ccggcccttc
     9721 attgttttgg atcagaaaaa atctgaagga tttagtgatg ccgtacgaac agacgatttt
     9781 cgcggtggtt acctagcggg catgcacttg cttagtctag gacatcaaac gatcgccctt
     9841 gtctatcctg aaaatccacc ggaaaatgtc cacgctcgga ttgaggggtt taaatctgct
     9901 cttgatgttt accaaatccc tcacgaccaa ctgatcctct tacctacaca gttctcaaaa
     9961 caaggtggct accagatcac agcagaactt cttgattctg ctgcaactgg tgtgtttgct
    10021 ttaaatgatg aattagcttt tggattatat cgcggattag aggaagctgg aaaaagcatc
    10081 cctgaagact acagcattat tggctatgat aatatagata tgtgcgagta tatcaagccg
    10141 aaactgacaa cgatcgcaca accaatcttc gaattgggac aaacatctgc caagttattg
    10201 ttagatcgga tccaattccc agaaaaagaa tgggaagaaa aaagattacc tgtacgatta
    10261 gaaaaaagat tttcaactgc acccttgaaa tagctttcaa ggtgtgctat atttttatcg
    10321 aactattaaa acgttttact aaaacgtttt aaaaaataat tttcccatca aaataaatga
    10381 gatagttgga ggtttgtaaa atgaacacgg ttacagtaat tggaagtatt aatatggaca
    10441 ctacccttcg tttaaccaac atgcccaagc caggcgaaac gatgcatgcg catgagattt
    10501 ttcacgctgg cggaggtaaa ggtgccaacc aagcagtggc agccaaacgt tcaggcgcac
    10561 ggacatcttt tattggaggc gttggggctg acagcgaagg acaacagtta ttagatctac
    10621 tgacaaaaga aaacatcgat acatctggga tagctgaaat ccaaggcgcc acaaccggac
    10681 aagcaatgat tatggtagac gcagcaggag aaaatagtat cttgatccat gcaggggcaa
    10741 ataatgcttt ccatgaacaa gaagtcctaa aaaacaagca actgattaca aacagtgact
    10801 ttattattgc tcagtttgaa agtagcttag atgcgacgat cctagctttt tctattgcaa
    10861 aagacgcagg aaaaacaacg atcctgaatc ctgcaccagc tcgtgaaacg attcctactg
    10921 aactacttga aaagacagat atcattatac caaatgaaac agaaacagaa atcattacag
    10981 gaatcagagt gacagatcat aacagtttgg tcgcagcagc cgaaaaactc catgaattag
    11041 gtattggaac agtaatcatt acactaggca gtgccggcgc tttctatcat acagaaaaag
    11101 aacacggtat cgtccctgct tttaaagtgg atgccgttga cacaacagcc gcaggtgata
    11161 catttattgg cgcattaagc agcacacttc agccagacct tagtaacttg aaagaagcga
    11221 tcctttatgg aaatctagcc tcttctgttg ctgtgcagtc ttatggtgcg caaccttcta
    11281 tcccttaccg cgaagcttta gaacaatcag cagtctaaaa ttaacaatga gaggaagaaa
    11341 caaacatgaa aaaaggaaaa gtaatcaatt cagatatttc acgagtaatc gcacaaatgg
    11401 ggcactttga taaattaagt atcggggatg caggcatgcc tgtccccttt ggtactgaaa
    11461 aaatagattt ggctgtctca aacggtcttc caagtttttt atctgtttta gaaaacgttt
    11521 tagaagaact tgaggtacaa tcgattgaat tggcggaaga aataaagaca atgaacccgg
    11581 aaatattgga aaaaatcaaa ttattgttac cagatacacc gattagcttt atcccacatg
    11641 aagaaatgaa aaaagagttg aataactgtc atgcatttat tcgtacaggc gaaatgacac
    11701 cttacgccaa tattatatta gtgagtggag tggtcttcta atggaaacga caatgaatcc
    11761 tgaacagatg gtactgtccg agcagattca tatgctgatt gaacagttgg gaggaaaaga
    11821 caatattgat tctgtccttc catgtgcgac tcggcttcgt atcaaattga aaaaacagcc
    11881 agtagccaat gcagaaaaat taaaacagca aatcccttcc attaagtatt tcattttact
    11941 cgatagatat gcagaaataa tcatggatca gggattggct cctgcttaca aggaattgac
    12001 gcgtcaaatc gatcattcag ctccgaaaga aaagctaaat ccgatcgaaa aactatttgg
    12061 tttgatatcg gaaatcttta cgccgatcat tccgctgttt gccggttctg gtatattaaa
    12121 aggtctggtt gttttagcga ctacgattgg ctggcttagt gaaacaagcg gaacttatca
    12181 tattttgtct gctgcgtcga atgccgtctt ttattttctg ccaatctttc ttgctttttc
    12241 tgctgccaaa acgtttaaag tgaatggata tattgcggct gtcattgctg cagcactgat
    12301 tgaaccgaat ctgacctctt tactttcaga cagtggcaaa gcagctactg attttctggg
    12361 gattcctgta gtactgatgc agtatacgtc tactgtcatg ccggcgattt taggtatttt
    12421 cttttattct tttgttgaaa aattcctcaa aaaatatatt cgcgaaaata tgcaattagt
    12481 atttgtacct ttactttcat tagttatcac ggttcctttg acgttaatgg tattcgggcc
    12541 tgcgggtgtt taccttggcg aaggtttagc tgccgcaatt acttggatga tggatattaa
    12601 cggaccgatc agtggcgcaa tcatcgctgg tggttggaat attttggtaa tatttggtat
    12661 ccaatgggct gtaaaccctg tcatgatcag taatatctct gcttatgggt tcgaccgaat
    12721 cgttccgttg acaggagcag ccaattttgg aatggctggt gcagctttag gtgtatttct
    12781 gcgaagtaaa cgttcaaaaa cccgttcgat ctccggttct gcttttgctt cgattttact
    12841 tgcgggagtg accgaaccaa ctgtttacgg aattgcgatc ccattgaaaa aaccatttgt
    12901 tgctgcttgc attggtgcag ctgctggtgg agctgtaatg ggatttgccc aagtgaaagc
    12961 gatcgctttt gtatttggta gtctgaccac attgcctgca ttcatttccg gtactttttt
    13021 ctggtactta gcaggactgg ctgttagtct agtcgtagca atgatcacta ctctcgttag
    13081 cgggtttgat gaagacctaa tgtcttatga atagttaatg aaaaagactg aagtatgaga
    13141 tgtttatcac atatttcagt ctttttcttt ttaggatcat tatttttata aatttttgtg
    13201 atactttcca aactttggta taatttacat atgcataacc atttttatcc ccacttgttt
    13261 atccccaaac aaaggtggtc tatgcaataa aatgaacgtc aaagaaaaac gaatgaatgc
    13321 tcgttgctta tttacaaatt gttttattta gaatacacag acagatttat gaaaagaaaa
    13381 agcttttcga cacgattatc tgttccaaaa aatgtctaat gaatgctgaa taagacagaa
    13441 aatcaatgaa aggaaaagga ctagtttatt atgaaaaata aaaaaacgat acgtttgcta
    13501 gctgctactt ggctgattgc tccgtctgtt ttgtcgacca ataccgtatt tgccgtagat
    13561 aatcaaatag ctgatcaaac agtcacaaca gatacgacta catccagctc agctactagt
    13621 gaaacaacgg attcttttac agaagaccca actggaacaa ctaactcaac aacaggatcg
    13681 accgagccaa ctgaaattga tccggctgat ccatcagaaa atgaaaagcc agccgagaca
    13741 tattccctta caattgctcc ttctttgatt ggtaagatcc aactgactgc ttcgacagcg
    13801 gattcccctg aacagcaacc tttggatatt acggaaagtg gaacggtaga aggtttatta
    13861 gcggaaacga aggtaactta cactattacg ccagctgaag gtgaacaaat tgcttcagtc
    13921 gctgttaatg gtgccaaaga agtaaattat gatgcaaaga cctttacagt aggtacgaac
    13981 aatttatcta ttactgcaga atttaaagct ggaccggata cttcaacaga gaaaccaact
    14041 gatcctagtg aagaagtccc tagtacacca gatccggaaa cgccaaacaa accagatgtg
    14101 ggtaataaca acaataataa tggttcaaat aattcaaaca ataataacaa taattcgaac
    14161 agcgggaatt cttcgaatca aacaaaccca tctggatcga ataacaatgg aaatactcag
    14221 agagaaccaa accatccaaa caatggttca tcgaatggcg gaacgaacaa tgcttcatct
    14281 cgtccaaata cagcaaatca aagcggtata gagaatccat cttctgcttc ttctgatttt
    14341 gttgtaaaat caccaattga tgctgtattg cctacaaata caacgaatgt ccaacaagca
    14401 atcgttcgag aagcattcaa gcatcttgga aaaccatatg tatggggagc aaaaggtcca
    14461 aatacttttg actgttctgg tttgacttat tacgtatata tgaaagcaac cggtcattat
    14521 atcggtggct ggacaggcga acagcaatat gcaggtacgc agattccagt aagtcaggcc
    14581 caacctggcg acctcgtctt ctggggacct tcttccggtg ttactcacca tgtaggtatc
    14641 tatattggga acggacaatt tatccatgcg cctcaaccag gagataaagt tcgagtaact
    14701 tctatttcag atttcacgcc tgattttgct gtccgagtaa acttagcagg tttacctgct
    14761 gcttcaggtt cgctgacagg cggctcatct attttagatg gattagatgg ctcgttccat
    14821 ttcagtcaaa accaaacaac tgatcagttc ttgaaaaaga ttgcagatga tgcacaggaa
    14881 atcgggcaaa aagaaggaat ctacgcatca gtcatgatgg ctcaagctat ccttgaaagt
    14941 ggatctggaa acagcttatt atcaagcgaa ccaaatcata acctttttgg tatcaaagga
    15001 tcatataaag gaagcagcgt gaccttcaat acacttgaac aagatagttc cggacaaagc
    15061 taccaaatcc gcgcacaatt ccgtaaatat ccttcttaca aggaaagttt ggaagactat
    15121 gccgacttga tcaaaaatgg actgactggc aatcctgatt tctacaaacc aacttggaag
    15181 tcggaaacaa aagactacaa agaagcaacc aaatatttgg aaggacgtta tgctacagat
    15241 cgccaatatt cacaaaaatt gaacgcgatc atcgaagcgt acgacctgac aaaatatgat
    15301 gaaccgaaaa aagaagcagc aacaactgaa gaagcaaacg ctgaaatcct caatatgtct
    15361 aagcgattcg atgtgccaat caaatggaca acagatggcg tgccaatcac aggattagaa
    15421 ttttcaacga taaaacgcgt caacaacgct tcttccatct tccgtgtcgc ttcaatctgg
    15481 gatttgtgga acaattttac ggcaagacag ataccagaaa caactactcg tacagttaaa
    15541 gctgcaactg ttcctgtact aaccttgtta aggttagaca aatcattctg gcttgatctg
    15601 cctttaaaga aatagaataa attaaaaagg ggatgtgaca ctgtcacact ccctttttaa
    15661 tttattctat ttctttatat ttattttgta ttccgttaca aactcgcgta cttggttagg
    15721 ttccagagtg acatctccaa aactttcaag tcgctccgct cctggcagtt cttgagtctc
    15781 aaatgtgata ccgccatgat ttactaattt attcccgcgc atttccggtc catcttctcc
    15841 aaaatttgct gtaaaaatca cgattcctga agcatctgtt tttacttgga tcgatacttt
    15901 ttcatctggg cttgtcaatt ccgcagcatt tagtaaacca gattgttttt tcaacaaaaa
    15961 tggatgatcg atgccgccca ctatcattga ttggcgaaaa tcactggcaa agacctcacc
    16021 taatttttta ggacgttgga agtcaaatgc tgtgccactt actgaaacta cttctcctgt
    16081 aggcgttgta tctttattga gcgtagcaaa taatcggcta ttcaaccaaa gtatatgttc
    16141 gtcgattgac tgtgctggat caccggttaa attgaaatag acatgatttg taggattgaa
    16201 tactgttttg cggtcactga tcccttggac cgtcactcgc catgtatcat cgttcgtcag
    16261 cgtataccgt acttctacat ctaaagttcc aggaaatccg ttttccatat ctgggctagt
    16321 ctgatagaaa atgaccgatg cttcgttttc accattgatg actgtataat gccactgctt
    16381 ggcttcaaag ctaggtgcac caccatgtaa acaatgacca gtgtccgggt ctgtttttac
    16441 ttcgaacgtt tcatcatcta atttgaatgt gccattcgta atccgtccag ccatacgtcc
    16501 gattgaagca ccgatataag ggtctttttc tagatattct tttgcttcat caaaacctaa
    16561 gatcaactct cgtttttcat tatcgattat tgtttgaaaa tgaacaaccc gtgccccaag
    16621 atcactgaca gacaaagatg tcccattttg attcgtgatc gtaatcaagt gatagttttc
    16681 gccaaaattt tgttcattga tttccatgtt ccttgcaccc tcttttcttt catttgcact
    16741 gattccagta tacatggaaa ccgttttctt aacagcttat tccgtgagta acgagaaaaa
    16801 atttactata ttctaataaa agaccgtgaa aaaaaggttg tgacaaaaat attgtcacaa
    16861 cctctttttc cgaacaaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaaccaa
    16921 acgaaaaata tgaggagcta tttttgcttg gctgttctta ttacttgatg caggacagct
    16981 ttttcacaat ctctttttca atacgattcc agtatataac catgtcgtca gtacatagta
    17041 gatgaaatac aatacgaaga atatcgtaaa cggaacccaa atatctttgt atggattttg
    17101 catgaataga ccaaacattt gtaatccgaa taagacatgg actacaccta agattcctgg
    17161 tgctaagaat aacacgccta cttctctacg gatcgattgt ttaagcaacc cgcgtcgtgt
    17221 tcctatcttt tcaagcattt cataacgagc aatgtcactc ttgcttcctg acaagatctt
    17281 gaacatcaaa cagctagcaa gcatggtcaa gaaagctaaa cctaggaaga atcccataaa
    17341 ttcaaaacca gagaatagac cattatacac ttcatacatt tcatatttct ggttgctgta
    17401 ctctactttt tgcaaagatg gattgttcat tttattttga gcaacaagtg tttcgattgg
    17461 tttcaggttt gcttggaagt cttttacctg aactagctgt aaagtggatt gtggcaagtt
    17521 cagttgatca aattctgatt gactgactac cttgatttct ttttcttgct gttccggcaa
    17581 ttcatagctt cgaagttcct cttgtacagt cagttcattc atttttttag caggaacttt
    17641 ttctttcgtg atcttcggcg gtgttccatc ttcatgtttt atcatgatca atggttgagc
    17701 cgcaaattca cttgcattat agtaaatcgt tcccgcatct tctttttgag tataagaagc
    17761 agaaagtgtt ggtgaaagtt ctttgatttt ttgctgatct tctgcccgag gattattcat
    17821 cactagatca tatccagaat tgttttctgt caagtctgca atttcatttt taaaacctaa
    17881 tcctaccgtc aaagcgccca gtgccaaggc aaacagcata gcgaccattg agagcatttg
    17941 tgtatattca cgaatacgaa agtttaactg tgacaatgtg aaattgttca attttttcaa
    18001 tgaaatctgt tctgatttct ttagtaatga taaaaagaaa atgatcacag aatggaaaat
    18061 gaaataagtt cctaatacga tcgtaactaa ggctacccct ataccaaaga cttgataggt
    18121 ccccacgtgt ttcatcatat agtaaccgca gcctagaaaa gcaattccca gtactacttc
    18181 aaggaaaaac aagaatttat gctgcttgat tcttgttggt gtctgatccg cacgaatcaa
    18241 tgctaaaatc ggttttttga caatcgaaaa agcattgaca acagcagcta ataaaaacaa
    18301 aacagcaaaa aacaaaacag tgatcaacaa cccgtgaata ctaaaaggtg taaaatgcga
    18361 aatattgaga tctaactgat ccactaataa tcggtggacg atacttgtca atcctacacc
    18421 gacagctgaa cccactaaag tagctgcgat ccctactaag aatgtttcag aaaaaatcat
    18481 ctgtgcgatt tttctgcctt ttgctcccag catcataaac attgcatagt ctttttgccg
    18541 catcgtcatc aaaaaggaat ttgcatataa aatataaacg aatgtgatga tccctagtaa
    18601 aacagaaccg aatcggaaaa tgataactgt agccgcaacg atcgtattac ttttcaaaaa
    18661 agcttcgttg cttgccattg attcaaacat gtaaaaaata gcagatgcca taactaatcc
    18721 tgagaataac accaagtagt ctcttaaacg gctcttgatc ccagtaagtg ataatttcca
    18781 aagcatagtc aatctccccc tactgttcca agtttccaag aatagatagt atttctcgat
    18841 agaaggaatc acggctttga tctccacgtt tcacttcttg atggataccg ccatccttga
    18901 tgaataaaat acgttggcaa taacttgcag aaaacggatc atgcgtcaca agaagaatcg
    18961 atacatgatc ttttgtattc aattcgtcca tcgtatctaa aagatcccgg gcacttttgg
    19021 aatccagcgc acctgtaggc tcatccccta atagaatcgt tggttgtgtg atcaatgcac
    19081 gtgcggcggc gacccgttgt ttttgtccac cggaaatctc agaaggatag ctttccaaaa
    19141 tatgagagat ggataaacgt tctgcaattt tttggacacg ttgcttgatt tcttttggtc
    19201 tgacgccttg taaagaaaga ggaacagcga tattttcttg tgctgtcaag ctttctaata
    19261 aattgaaatc ttggaaaata aagccaatct cattcgcacg aaaatctgct agttgatttc
    19321 cttttaatgt ggtcacatct ttttgattga ttcggatatg cccatctgtt ggtttatcta
    19381 atgtggataa aatattcaaa agtgtcgact taccagaacc agaagcgccc atgatcccaa
    19441 taaattcgcc tttttctaca tcgaagctga tgccgcttaa tgcttgcgtc tttttctcat
    19501 tgttttttcc gtatactttt gttacattct gtacttcgac tattttgttc atttctttcc
    19561 ctacccttta attagttttt ccagtgctgt tttcggcacg tctttttttt cgacttcttc
    19621 atacgaagtg acacctttat ttttgttcca ggtgattttt aaatatgctc ctttacgaag
    19681 cggtcgagtc aattgtccct tgaagtccag ttctttttcc ttaccctctt tcgtatagcc
    19741 aggcaggata tatctatagt tgactgtttc ttgtccagag tctgattttg aaactgtttt
    19801 tgtaccatct gtcgtaattt gtacatagta ttcttctcca cccataacta cgtaatctgc
    19861 gattttcacc cctgcaagta ccacaacgat gaaaacaagt agaccgatca gaagtttttt
    19921 cactttttcc ccttctctct tactttatat actgattata gaaaaaagcg aacaattctg
    19981 ccttcgaatc aactatcatt cttctttcaa ttttgtcatt ttctttaaaa caactaaaaa
    20041 aagagttcaa gacaataatc cgtcctaaac tccttcttcc tatcttacaa aaagtatgtc
    20101 acttacggtc tttcatgtcg cctgtattga taacaggttg cgttcctttg tctgtaatga
    20161 ttgagacaag taaattattg atcaattgga ctttccgatc atcggtgaaa ttgatttctt
    20221 gtccatcttc gatttgctct aaggccattt gagtgattgt gacagctcct tcaacaatgg
    20281 tttgtcgagc agacaaaatg gcttttgctt gttgacgttg gagcatggca ctagcgattt
    20341 ctgttgcata ggctaaatgg ttcaagcgtg tttcgattac ttcgacacct gctactgcta
    20401 aacgctcttg cagctctttt tgcaactcgt cagacactgc cgtcgtgttt cctcgaagcg
    20461 tcaaatcatt ctcattgaat gtatcatacg ggtattggct agcgatatgc cgaatggctg
    20521 tctcactttg gatttctaca aaatcttgat aatacgctac atcgaataat gcctttgctg
    20581 tatcaacgac tttaaagact actactgctg agatttcgat ggggtttcca tccaaatcat
    20641 tgacttttaa aacagaacta ttgaaattcc gaactttcaa cgaaacagtc attttttgtg
    20701 ccaaaggtat cgtaaggaaa aagccatttt ctcgaatcgt acctaaatat tgtccaaaaa
    20761 acaaaattac ttttgcttga ttaggactga ctacagttgc cgaacttaac aacaataacg
    20821 tgatcaacca aagaaaaata cttaaaaaaa gtgcccaaac tttcgcttgc cacataccta
    20881 aatagaagaa aaacaatcca actaaagcta atacgaccaa tccgacaatc cctgcataac
    20941 cattgatata aaatgctctt ttttctctca tgctacttcc tgcgctcctt tatccttcaa
    21001 taaatatcta atgttacttt tttaattttt ttttcgaata cgcgccatta caccttctag
    21061 ttctaactct ttgtcttcag tgatgtacca accgcttgcc tgtgtccctc cggctgcctg
    21121 cggtaaataa tccaattttg ttcgaaccca gtgcttttct tctgtaaaat agtcttctac
    21181 caagacctct agatccatcc ctgctgaaag aggcaaatct tcccgaacag atttaaagat
    21241 aaatcgttcc ttcttcccat catacttcaa tattcctgta tcgataatcg gtaaagaata
    21301 ataatccagc tctttcttca ccgtcaataa atgtttgaaa acttcatggt acacttgctc
    21361 taattggcga ccttctgaat tgttcgggta attaaccatc actttttctt tgtctggatc
    21421 atagaaggtt tggcttagtt gagtgatata agtatgtaat ctttccattt ctgtttttaa
    21481 cttttctctt tgaccttctt ctaccttcat atactctttc accctgtttt ctttttagat
    21541 attttctttc ttattttact atagttatgt gcgttaagcg atgaaaaaca gcaaagattg
    21601 gaaggatctt tgctgttttt tcttaaaata tccagttgag tacaggatca atctgtttca
    21661 ttgtcctctt gatccgtcgt aatattgatc gatgtgtctt tagcagtgat ctttagcttt
    21721 ttctgtcctt gttctaacaa agtatttgtt attggctggt agtctttttc aatataagat
    21781 tcaccagacg tttggatagt atagccactg ttttccatct catgcaaaga taaattgcca
    21841 ccgtttagga tgacttttcc ttctttgctg atcaaactgt cttctagatg gaagttgctg
    21901 ttttcacctg tgacgatcaa gttatccaca ttggcctcat ctaatcgaag tgagcctaat
    21961 tcatctttcg cagttattgt tcctcctgta aattcattga acgataccca gccatcatgt
    22021 gtcttagtat tcactttttt gattgatact tcgttgatat caattgcact attattccct
    22081 tcgattgtca attcagataa ttcatgatct gcagggacaa caatagtgat ttgtgcactt
    22141 gtgtcttcta aactaatgat tgcacctgtt gattttttga ctgcattcac agtcaacacg
    22201 ccatttttct cctttatttc tggcttttct gtcttatcat aagtcgtttt tatctcaaaa
    22261 tccaatccgc gtatgaccga aactgtttga ttttctgcat ggatgacgat tttgtttgca
    22321 tccttgattt tttttgtctc agtaaccata tcgatcaacc gaggaccatt atcccaagtc
    22381 agactctttt gagcgcctaa tgtataagtt gcacctgcta ggaggccacc agtaagcatc
    22441 agaccaatac cggtaatcaa aaaatgtttc aatctcaatt tatgtgtcct ccttcaaacg
    22501 cccgctgaat gcagatctct ttttgtaata aaacgtcgtc ccatccattt aacaaagttc
    22561 atcatgacat aaaaaagccc ttttgttcct ttcagcaaca gtggcgaaat aaatactgcg
    22621 cttcctgtgg cgaacagacc gacaccgata aagaataatc cactcagaat cgattgtcca
    22681 aacacactga ttcctgagat gatcatgaat aggccaacac ctaagatact gatacataaa
    22741 acatagatac taaaaatgag cgctagtaaa gcaaccaata gtcccccaat aaccaatata
    22801 aaccccagtg ctagtggaat gaggacagga gaagcaaata aaccgataat gattaaccaa
    22861 atcaggcgaa tttgtctttt tggatttttc actaactcgt tttctgcttg ttcttcttct
    22921 gaaaagtaac tgatttttaa ttttaaggca aactgctttg gtgtaccata ttcatcaatg
    22981 atctgatcta atgtttttcc agaatctaaa aaatattcct cataatactg gatcaaatca
    23041 aaacgatcgt cttcaggaat ttcttgaaga tgatccacaa cttcattcaa atattcattc
    23101 atttgtgctc tcctccaata accggtctaa agaatctcga aaaacaatcc attcatcaat
    23161 aatttcttct aaatgacgac ttcccattgg tgtcaacgag taatatcgac ggtttctgcc
    23221 ttcaaaaggt tcatcatagg tctcaagata tccttctttt ttcaatcttc tcaaaaccgg
    23281 atatagtgta gattcactga cagagagact ttcttgtacg atttttgtta aggcataccc
    23341 atacatatct tccttgctta atgctgctag cacagtacca tcaagaagaa cagttggaat
    23401 ctggatgtgc attacgtcac cttctattct caagtgtaat attttatttc aatctatatt
    23461 atacaacata taatatagtt tcaaaatcag tttgtcaaat acaaaaaaac tgactaaaag
    23521 atttgatcct ttttagtcag caaaaaatgg cttctctttg atttttatta taacagtggc
    23581 ataatccaat ttgtccacat ccagctcagt ggcatgataa cgatcattgc aggtatcatg
    23641 tcagctactg ggaacatttt cacgttgatc attctaaaac cggtagcgac catcaagaat
    23701 ccgccgcaag ctttaaaatc taagatcatg tctggtgtag tcaatggata aataaatttt
    23761 gccaataaga acaaaatata aaaaataatg aattggggaa ttgctatcac agaaacgaca
    23821 taccctaaat tacacgcaaa aatagctgct gtgaaaaaat caaggacaga tttagaaatc
    23881 aaaatcgtac tgtctcctgt catcccagaa tctaaacttc catagatccc cgtaccactt
    23941 gcacaaaata gaacaatgac cgtcactaat gtgctgataa attcatcgtg ggtcatacca
    24001 agcttttcac tagggaagat tttagaaata ggtacttgca tcagcgcagc ccccttattt
    24061 atcccattac ctaaatgaac aatcaaacca atcgctgttc ctatcactaa agcaaaaata
    24121 acagccggca tatttttcat cggcgcaatg gaatagattc ccatccccat cgaacacaca
    24181 ccaaaaacca tcgtcagctg tgctttaaaa tgttcactta atttatttcc tactaatccg
    24241 ccaattagtc cgccaaacaa aacggaacct acattgatca aaactccagt tggcatcaaa
    24301 aaactcctct ctttttctac gaagcgaaaa aaatcagaaa aatttctgta attattgctt
    24361 tcgctgcaag aaagattgta acagacagag aagattacac caattcattt tttgtgttaa
    24421 agtattcttt attggaataa gtaggaggaa tatgatggat atccataaat tcgaagtttt
    24481 tcttgattta gccgaaacaa tgaatttcac caaaactgct gatcgacaat tcaccaccca
    24541 aggaaatatt tctaaacaga ttctttcgtt agaaacagaa ttagacgtca aattattcga
    24601 acgcgcccat agaaaaatcg aattgaccga agctggaagc ttattgctcc catatgtaaa
    24661 aaatgtcgta gaacaatacc atgctatgca agaagtgctt gaaacctata cgaaagacaa
    24721 caatctttca ttaaatatct taacgatacc gacaatgatc aattataaag gtttttccaa
    24781 aatcaccgag tttttgaaac gccatcctga atttacagtc cagttgaaag aagtggaaag
    24841 tgtcgaatta acttacaatg acgccaatga acatagtgac acgatccact ttgctagaag
    24901 tttccaggcc ccaccaagtt cgattgagtg gttgcctact gaaacagacg attttgtagc
    24961 agttctacct aaaaatcatc ctttagctag taaaaagaaa ttggatctaa gcgaactgaa
    25021 aaaggagaac tttttgctcc ttggccccac tacgaacttg tatcaacctg tactagatct
    25081 gtgtcgcgaa gctggatttg aaccaaaaat ctcttataaa ggagcaagaa tcgacttgat
    25141 catcaatatg attgcaaatg acatggggat tgctattgtt atggaaaaaa cagtcaagaa
    25201 tctattaaaa gaaaatactg tgattctccc tatttctcca acaacagaga gttatcttgc
    25261 atttactcgt aaagtcggtg agcattcttt ggcttcagat acattttggg agtatttaaa
    25321 tcaagaagaa aactaagccc tacattttct gtccatctat ccacccaaaa aaagagagcg
    25381 acgcatgact ttcgctctct ttcttgcatc atgtccttgt ttcaatgaca cctctaacat
    25441 ttctcgtagt tcaataagaa agcagcgatt tttatgccaa aagaaccgta agaacatttc
    25501 cctaatcaca aaaaaacgac taaaaacccc taaaaacctt caatagaatt tttaggggtt
    25561 ttattctttt tcctattgtt tacttaaccg tatcattgct gtcgttccta ctccttcgat
    25621 actgctataa tcaatacgtc catcatgcag ttctagaatt tttttaacca gtgaaagtcc
    25681 tagcccattc ccagaaattt gacgacttgt atctccttga taaaattttt caaacattcg
    25741 atctctggtc tcttcattca ttcctacacc tgaatcggtc acttccagta caatctctgt
    25801 ggctgtctca aatagtttga tatgaatctg tccattgatt tgattgtact ttatggcgtt
    25861 atccatgata ttcagccaca cttggtacaa aaactcttca ttgcctgtgt aatttactgc
    25921 agcaagttcg atatccaatt ctagctgttc tttctcccat ttaggctgaa aaaaaacgat
    25981 tacttctctg atttgttcat ctaatcgata ctctttcttt tccagttgga tacgctggtt
    26041 ttccagtttg ttcaatttta agatgttctc tgttaattgt gaaagctgcg tgatactttc
    26101 gataatccga tataaaaata tttggcgttc ttcgtcagag agatttgggg cttgtaacaa
    26161 ttgaacatat ccttggattg ttgctagtgg tgttttgaat tcatgggata cactggacac
    26221 aaagtcattc ctcagtgtct cgatactatt gagttcttgg accataacgt tgaaatcttt
    26281 atacagttgc tgtacttctg ctactttctg ctgttcatcc attcgaatcg aaaaatctcc
    26341 cgttgctacc agactcatat ttgtccctag cgcactgatt ggatgcagga tacgccgccc
    26401 aacaaaaatc gatattcctg tacccacgac catactgaac cccgcaaaga cgaataacgg
    26461 gtataacgtt ggttttccag ccgattcagc aggcgagata gaatgtcgag acaataagaa
    26521 aataaaaccg agaaaacaca gcagtgtcac taagatcgaa atgaagacaa tactagcaaa
    26581 atagatccat aattgtgaaa atagcttttt tttcatcttt aaataaccgc cttatagcct
    26641 agtccccgta ctgtgatgat ttgaaaatct tccgtctttt caaaacgggt ccttaaacgt
    26701 ttgatatgta catcgatcgt tcgttcttct gtattcgtat ctaatcccca aatatcatcc
    26761 atcaactgtt ggcgagtgaa gatcttgttg ggataagaca gtaatttata cagaagcaga
    26821 aattcttttt gaggcagaat caacgaatgc tgatcttgta acactgtata agcatctagc
    26881 tctaattttg tttgtccgat tatcaagcta ctgctgtaat tgatctttga acgtcgaagc
    26941 aatgcttcca cacgtaggat catctcattg acatcgatgg gttttgtcat ataatcatct
    27001 gctcctaatt tgaacccgcg tttcttatcc tcaaaatcgg cctttgccgt aatcattaga
    27061 acaggtgtgt caaatctggt gctacgtaat gagtctagca agtcatagcc atccattttc
    27121 ggcatcatga tatctgtaat gattaattct atacgtgtcg cttctagttt tttcagcgca
    27181 tcctctccat tcaatgcggt gatgactgaa aagcccgctc gttccaacac agaacggtaa
    27241 agcaactgta attgcggatc atcttctact actaaaatac gattcattga tctccctctg
    27301 ttttttgaaa aatttctaga ttttttcttg tagttcatct tcagttaaca tttatttcgt
    27361 atactacgat cattgttctg atatacttat tagtataccg aatatttcaa tacgggagaa
    27421 gggtgattat gcttcaatta aaagatataa aaaaatatta taaagtcggc gaaaccacca
    27481 ccaaagcatt ggatggtgtg tctgtcgctt tcagacaaaa agaattcgta gcgattttag
    27541 gtcctagtgg ttctggtaaa acgactatgc tgaatgtgat tggtggacta gataattatg
    27601 attccggtga tatggtaatc aacggaaagt ctactaaaga ctttaaggac agtgactggg
    27661 atgcctaccg aaacaactct atcggtttca tttttcaaag ttacaacttg attggtcatc
    27721 taggcattat tgaaaacgtt gaacttggga tgacattaag tggtgtttct aaagacgaaa
    27781 aacgaaaacg ggcagaagat gcattgcacc gagtcggctt gacaaatcat atgcataaaa
    27841 agccaaatca gttatctggt ggacaaatgc agcgagtggc catcgctcga gcactagcca
    27901 atgacccaga tatccttttg tgcgatgaac caaccggagc gttagataca gaaacaagta
    27961 tccagatcat ggaattgatc caagagttat cgaaagaaaa attagtgatc atggtcacac
    28021 ataatcctga actggcccat caatacgcag atcgaatcat tgaattttct gatggtaaga
    28081 tcttaacaga ttcccatcct cacatcgaac gaccaaaaga tgatcaattt aacttacgca
    28141 gaacaaagat gagtttttgg acagcgttaa agctttcctt caacaatatc cgaacaaaaa
    28201 aaggacgtac tttcttgacc tcctttgctt ccagtattgg gatcatcgga atcgcgatcg
    28261 ttctgtccct ttcttctgga ttccaaaaac aaatcgataa cacgcaagct gaaacgatgg
    28321 cgaaatttcc gattactatt tctaaggtaa cgactaacca gactcgtgac gatgccggat
    28381 tgggtgcaag caaagcggat tatccagaca gcaaaacgat tactgcaaaa gtcagcgaag
    28441 aagataaagc acagcacacg aataagattg atcaaacata cgtcgattac gtaacagaca
    28501 tcgatcctaa cttaagtaat aatatcggat ttacccgtac tacaggaatc aatcttttac
    28561 gtgatgtaaa tggcaaagta cagcctgtca gcttctcgaa tcaaaatcct gatacggaat
    28621 ctctttcttt atctagtacg atgtcagcaa tgacaggtgt gggagtgtca agtttcccta
    28681 cacagcttga cactagcaaa gaaaactttt taaaagacaa ttattcttta cttgccggaa
    28741 gttatccagc ctcagcaaca gatgtcgtgc tgatcgtaga cggcaataat aatactaata
    28801 tcaacgcatt gaagaatctt ggatttgatg tgaaagaaga cgaaaaactt gattttgatg
    28861 atatcgttgg tacaacattc aaattagtaa acaacaatac ttactataca aaacttccaa
    28921 ctgggaattt tatccctaat acagattatg atgcgatgta tcagaatgct tctgatgaat
    28981 tgaagatctc ggggatccta cgcgtgaaat cttcttctac aatgaatctc ttatctccag
    29041 gaatcgctta tagcgatcaa ttaacgactc aaatcgtcaa cgaaaacaaa gaatcagaaa
    29101 tcgtcaaagc tcaaagagac agtggtgtaa atgtcttaac tactgaaaaa gttgacgaaa
    29161 atgccaaaca aacattgctt agttatttag gtggagacag cttgccttca agtatcatga
    29221 tttatccgaa caattttgaa gacaaagaaa agatcttgga ttatctagat gattacaata
    29281 aaggcaaatc agatgaagat aaaatcattt atactgattt agctggaacg atgactgaac
    29341 tgactggcgg attgatggat gctatcactt atgtccttat tgcttttgca gggatctctt
    29401 tagtaacaag tatgatcatg atcagtatca ttacttatac atctgtgatt gaacggacaa
    29461 aagaaatcgg tgtactaaaa gctttaggtg cacgtaaaaa agacatcact cgcgtatttg
    29521 acgcagaaac gtgtatttta ggtatttctt ctgggatatt aggtgtgttt attgcatggc
    29581 tagctacgtt ccctatcaat agcatcttat acaacatgac ggatctaaaa aatgttgctc
    29641 aactaaatcc tgtccatgcg attattctag tgatcgtctc tactatattg acgatgcttg
    29701 gcggtcatct tcctgcacga atggcagcga aaaaagacgc cgctatcgct ttgcgtgcag
    29761 aataaggttg tgacaaccac atttagattt gagtcataag agcgctgaaa tagtagaaaa
    29821 cagcaagaaa cgaggaagta atatgttcct tgtttcgcgc tgtttttttt aattattttt
    29881 tataattctg gtatactttt ctttcctttg taccacaact cttctggcgt atacctgtct
    29941 tttccattta tgaatactgt tccatctgct tcaatcgtta cttcagtccc aatccacata
    30001 ttacgagaaa gtgcgagaag attttttctt tttcctcttc ctttttttcc aaattgcaag
    30061 gcatcggtta tctcttctgt ccaatgagat ttcacgtatt ttacttctcc gttttcaaat
    30121 gtaactttca aaatattcgc tatattttcc acttttactg ctttaggaaa tgactcctcc
    30181 atttttttca ctttccttcc tccaacacta agtatgcgct ttcttttagt gataagtata
    30241 tcatagttta ttctattatc aaaaaaacgc atccattcca ttgtagaata ctttaccgaa
    30301 caagttgaat tgttttcctc tttttcacct tttactatag ataggtaaag acaactaagg
    30361 aggaatctct catgacagat caaccgtatg atttaagaaa agtcatcgaa gaactaaaaa
    30421 cacttccagg tcaatatcac gaaacagata ttgaaatcga tcctgaagca gaattatctg
    30481 gtgtttaccg ttatatcggt gctggcggta cagtaaaacg tccgactcaa gaaggaccag
    30541 ctatgacttt caacaatatc aaaggtttcc ccggcacacg tgtgaacatc ggaacaatgg
    30601 ctagtcgtaa acgtgtaggt gaaattttgc accatgatta tcgaacactt ggtcgtttct
    30661 tgaaagacgc tgtagaaaat ccaatcaaac ctgtgaaagt agacaaagca gacgctccag
    30721 cacaagaagt cgttcatcta gctaccgatg cagacttcga tattcgcaac attttgcctg
    30781 cacctacaaa tactcctgaa gatgctggtc catacatcac aatgggtgta gtcttaggat
    30841 cagatccaga aaaaacaatg agcgatgtaa cgatccatcg tatggttcta gaagataaag
    30901 atacgatcgg tatgtacatc atgcctggcg gacgccacat tggtcacttc caaaaacaat
    30961 tcgaagcctt gaataaacca atgcctatca ctatcaatat tggtttagat ccagcaattg
    31021 ccattggcac gactttcgaa ccacctacca ctccacttgg ctacaatgaa ctatggtgtg
    31081 caggagcttt gcgtaacgaa cctattcaaa tcgttgatgg tatagcagtc gatgaagtgg
    31141 gtattgctcg tgctgaattc atcattgaag cagaaatcat gccaaatgaa acaatgcaag
    31201 aagatatcaa cacgaactca ggaaaagcaa tgccagaatt tcctggctat actggggatg
    31261 ctaatccagc tgtacaagta gtgaaagtca aagcagttac tcaccgaaaa gacaatccaa
    31321 tcatgcaaac aacgattggt cccagtgaag aacacgtatc tatggccggt attcctacag
    31381 aagcaagtat tcttgccttg gtcgataaag ctattccagg aaaagtagta aatgtctaca
    31441 atcctcctgc aggtggtggt aaattgatga ccatcatgca aatccgtaaa gaaaacgaag
    31501 cggatgaagg tattcagcgt caagcagcta ttcttgcttt atcagccttc aaagaattga
    31561 agacagtcat tttagtcgat gaagatgttg atattttcga catgaacgat gtagtttgga
    31621 ctttcaacac tcgtttccaa ggagataaag atatcatcgt gatcccagga atgaggaacc
    31681 atccattgga cccatcagaa ttaccagaat ataatcctgg ctctattcgt ttccgtggga
    31741 taagtgcaaa aactatcttt gacggtacag ttcctttcga tatgaaagaa cattttgtac
    31801 gtgcaaaatt ccaagaagta gaagattggg aaaaatattt gaaataatga atgatctgca
    31861 actgttttga catcataaaa aggagtgcgg aaaatggaac aattggcaca acggaagaaa
    31921 aaaatcgtga ttggtgtaag tggcgcttca ggcaccattt atgccatcaa cctagtgaag
    31981 aaactaaaag aatatccgat gatagaaaca cacggaatca tcagtccatg ggcaaaacag
    32041 aacttaaagc tggaatccga cttatcacta actgaattcg aaagcctgtt tgattaccat
    32101 tattcaaaca aagatttagg tgctgctgtc gccagcggat catttttgac cgatggaatg
    32161 atcatcgtac cggcaagtat gaaaacagtc gcaggtatct ctgttggttt aggcgacaac
    32221 ctgattgcac gtgctgctga tgtaacaatg aaggagcaac gaaagttagt cattgttcct
    32281 cgtgaaacgc cattaaatgc cattcacttg gaaaacttga ctaaattagc acgactaggt
    32341 gtgcaaatca taccaccaat tcctgctttt tataatcagc ctcaaacgat ccaagatctt
    32401 gttaatcacc atacaatgaa acttttggat caatttgaaa ttgtaaatga gcattcaaaa
    32461 cgttggcagg gtgattaata tggaaaaaga aacgatagtt gaagtaacca aactaggttt
    32521 cacgatccaa gctgctgtta aagtaatcgg taaagactta ttgatcactt taacaggcgg
    32581 agatacacca catatcggaa cagtcactac attttctcgt gatacagaga tgcaaactgt
    32641 acgtttccct agccacgatg gtcggttcca taaagacgat gtcttagccg aaaaaatagc
    32701 tgtgatcatc aaaactgccg ttccgggaag ttgtacgatc acttccggta tccatgttga
    32761 ccatatctcc aatgcacaaa tcaacgcctc ttttccgatg tcagaagagt taggttacaa
    32821 gattttagat tggttggaaa aaatagattt ccatatcaaa taaccagttt attataaaga
    32881 tggtgaaaaa ccattatgaa agaagaggtt gtgaaatcag cgttatgacc tgagtatgag
    32941 agaaaaaaat ggaaaaatag cttctcatat tttgccgttt ttgagctaat accgagggac
    33001 agctgattga acgccgttta tcaagaggtt gtgataaagc cgcttcgttt cgagtagtaa
    33061 gaaaaatttt gtaaacatgg gtttccacat ttttgcataa atttgactta ctaccgagaa
    33121 actggctttt gaacaccgtt tatcaagagg ttgtgacacg tcttttgtca caacctcttt
    33181 tatttttgct tcactgtaac tgctacaata tcaccgattt cttttccgat gtttttacga
    33241 atatcttttc gtagtccaag gatgtagcag actgaaccat ctggattttt cacgcccata
    33301 ttcacgatac tgccttcata cggcacattg tcaaaagttg cttggacttt aactcttcca
    33361 gcaccgaatt cttttcttat atcatacgga aaaataatat atgccccgcc cttgccgact
    33421 tcggaagcat agatttttga ttcaaaagaa taaatttccc tcattttatt tctcctattt
    33481 tttacatcta gtatagcata gcaaaaaaaa gaaggaactg tgacaaaagt cttgtcgcag
    33541 ttcctttttt cgaataaacg gtgttctcct gccaactcct cggtcacaag tcacaatagt
    33601 caacaaacat gagaagctgt tttttgaaat tgctccttgt gactcagagt taaacggcag
    33661 gctcacaacc tcttccttaa acggtgttca aaagcttgca tctacggcac taagcccaat
    33721 cagatgaaaa atatggagtg ctatttttat ctgattgttc ttactgcttg atgcagagca
    33781 gctttttcac aacctcctac atggtgttca aaatattatt cgccttttgc ttctttcact
    33841 aattttgcga atgcttgttg ttggaattca gcagctaagg ctttcgtacg ttgttcttgc
    33901 tctgctttgc tcatttttgg attttcagtc attgctttta ccataccgtc ttgaacataa
    33961 gcttttgctt cactttccat cgtactttgc tgtttcttca ctaattcagc taacttggct
    34021 gcttggtccg tacttaattc tacccatgtc tctgggattt tgaatgtatt cactcggctg
    34081 tcatattcgt gattgttatc agcaatattg aaccagaatt tatacatgtc gtttttgtat
    34141 tcccaataag tagttttcgt cactttttca gcatcgccgt ctgtcttttc tactttattt
    34201 gtttcgttat ccgtaccagt tgcttttggt ttttcttgtt tttcatttgt tcggtaaaga
    34261 tacacttttt cttttccatt ccctaaagct ttatacaaaa gcatatctgc tccttgggaa
    34321 tcagcactgg aaacaatttt ttctgttttt gtttccgtta ctttttccat tccaaagtga
    34381 ttggacaaat tagcgacgat caaacttagt gaagcgacga agattagtcc gaaaatcaaa
    34441 gataaaaagg tttgccatgt ttttttagcg aacacgttcg ttaaagcaaa agcaagcaag
    34501 ctgacaatca aaactccaat aatcatgcat tatcccccgc tttcattaga acaggttctt
    34561 ttttcttcaa taaaaaggca ataataaagc caagaatccc aaagatgatc gctacgataa
    34621 acgcggcatg gtaacctgac agtgtggcat tgattgcctg atctttataa gctaatggcg
    34681 tattatccaa tacagatttg cttgggatat ttgcttttgt cacattcgtc aacacactga
    34741 tcaaaatagc tgtaccaatc gagcttgcga tttgacggaa tgtattattt accgctgtcc
    34801 catgactgat caagttattt ggcaatgcat tcataccaga agtcgttacc ggcatcatga
    34861 ccatggagat cccaaacata cggatcgcat aaaggatcac gatatataaa actggagtcg
    34921 tttttgtcaa gaaagcaaat ggtgcagttg ccgctgtcaa aatgaacatc cctgtgatgg
    34981 ctaaacgttt cgcgccgtat ttatcgaaaa tcgcacccgt cacaggcatc atagccccca
    35041 tgatcaatgc acccggcaac aacatcaagc cagaatggaa tgctgattct ccacgaatat
    35101 tttgaatata caatggtacg accatttctg cccctaccat cgccatattt gttacaccag
    35161 ctaaaacagc tgcaatcgtg aatgtagatg atttgaatac acgaagttcc aagaatggat
    35221 gttccaaatg taattgacgc catgagaaca aggcgatgaa aatcacacca acaactaaga
    35281 aaccaattac tttcaagctt ccccagccgt catctcctac actagaaaat ccgtaaagta
    35341 aactaccgaa tccaatcgtt gataaaatag cggataaaat atcaatgcta ggatttgaca
    35401 atggaataac acttttcatt aggaagaatg ctaaaaccaa gacaagaaca acgattggca
    35461 gtaccatacc aaacaagtca cgccaatggt agttatcaat gatataacca gataatgtag
    35521 ggcctaaagc aggagcaagt ccaataacga tccctgacat ccccattgct gatcctcttt
    35581 tttctggcgg gaaaatagat agcatgatat tttgcaataa tggcatcgat actcccacac
    35641 cgcaagcttg gatcaaacga ccgattagta atgtactaaa attaggtgct gtaaagcaag
    35701 taatcgttcc gatcaaaaag atcgtcatgg cagaaagata taaatttctt gaactgaatt
    35761 tattgatcag ccatgctgtt attgggatca tgatcccgtt gactagcaag aaaccagtcg
    35821 ttaaccattg cacatcagac gctgaaatat cgaaagcttt catcaatgta ggaaaagctg
    35881 tcgtcaataa ggtctgattc aaaacggtac aaaatgtacc aattaataag acaacaacta
    35941 aaagtgtccg attatatggt tttccgtaaa tatctacggg ttggttgtta ctcatatttc
    36001 tccttctttc tgaatttttt ctgaaactac tagaatactt tagtcctaaa ttcgctattt
    36061 gtcaacctac ttgacacata agttaatacg gatataatta agggaagcaa gaggacaaaa
    36121 ggagtgacaa aaatggttgg ggcttccctt aaacgtttgt tggaaaatga tcaattggtt
    36181 gttggcatca gtgaattaag tgatatcgta ggtgtgtctc cacgtcaatt aaggtattgg
    36241 gaacaaaagg gattcattcg ttcgatcgaa gctgatgcga attgtcctag aaaatatcgt
    36301 ttacctacag tcataaaagt agaactgatc aaaaaatatt tagatgacgg atttactttg
    36361 tcaaaagctg cagaaaaggc agaaatccgc caaaagaaaa tgcaccatgt ccgtaaagtt
    36421 ttttcaaaag caatcaaaga tatcgaattg atcgacgaac gctatacgat tttacaaatc
    36481 ggtaacttca aagaagagaa tgctaagatg tacatcattc atgacaacga gacagacgaa
    36541 ttaacttaca agctccttcc tgtcgatgaa aaagctgact acgaacagtt gttaaaagaa
    36601 ctctaaacgc cactaatctc ctaagtacca agctttttaa taagtagatg ctacataaat
    36661 acttgaaaaa aggcctgttt gaacataaga atatccgaac ggtgatctgc gtttctttca
    36721 tatagaaagg aattctccat cactgttcgg atattttttt atttttttcg gttactttct
    36781 tctaatacat ctgttagcca atttgcatat tctgtttccc gattgatcgc atgcgctaaa
    36841 atcaggtagt gtccgtaatt ttcatgtttt tctttttcag taggaaagat cgtttttttt
    36901 cgctctaata gatgaagtcg tttttcttca tgaaggtcac gctgctgctg aataatttct
    36961 actaatgccg gatcattcac gtctttgacg aaatacaatt tcagaacaaa ttcgtctcga
    37021 ttaaccggta gttcattggt gggtgtatga atccactctg ccaattgttc cttcccttct
    37081 tctgttaatt cataaacttt cttttccaat ttttcacctg tgatctctac ttgatgctga
    37141 atgattcctt gctcttccat ttttgcaagt tcaggataaa tctgactatg ttttgcttgc
    37201 caaaattctc ctatttcatt tttgaacgat tgattcaatt catatcctgt catcttcttc
    37261 ttacttaata accctaacaa aatatatcga agtgtatttt ttcttgccat cagttttccc
    37321 tccttgacaa atctttaaat ccattctatc ataaatgagt aatcgaaaac atgtagttta
    37381 ttacatgttt taatttataa ggagatgctt aaacatgaaa gaatttaaag aattggaaga
    37441 ttttattgga actcacttta tctatacgta tgacaatggt tgggaatatg aatggtatgc
    37501 caaaaatgac catactgttg attaccgtat ccatggcgga atggtcaaag gccgttgggt
    37561 aaaagaccaa gaagctgata tcgttaaatt gacggacggc gtattcaaaa tcacttggac
    37621 agagccaaca gggacagacg tggcattgga ctttatgcca aatgaaaaga aacttcacgg
    37681 aatgatcttt ttccctaaat gggttgaaga acatccagaa atcactgtta ctttccaaaa
    37741 cgaacatatc gcagaaatgg aagcagctcg tgaaaaatat gaaacttatc caaaattact
    37801 tgttcctgaa tttgctacga tcacttatat gggtgatgca ggtatagaca atgaagatgt
    37861 tattagcgaa gaaccatacg atggaatgcc agatgatatc cgtagcggaa aatacttcga
    37921 tgaaaattat aaacgagtaa aataaggttg tgaaagagag gttgtgaaat cagcgttctg
    37981 acctgagtat tagagaaaga aacggaaaaa tagttcctca tgttttgccg ttttttgagc
    38041 taataccgag ggtcagctga ttgaacaccg tttatcaaga ggttgtgaaa tcagcgttat
    38101 gctttgagta ataagaacgc tagttagaaa atagcttttc atattttcta ggctagtggg
    38161 cttattaccg agaagcagcc gtttgaacac cgtttatcaa gaggttgtga aatcagcgtt
    38221 ttgacctgag tattagagaa acaaatggaa aaatagttcc tcatattttg ccgttttttg
    38281 agctaatacc gagggtcagc tgattgaaca ccgtttatca aagattgtaa caactgcata
    38341 ttcacacagt taaattagtg acttcaaaat gaaataatgc tcccagcaaa aaattaggct
    38401 gggagcatta tttcgttatt ctgttcatca aaaatcagcg ttttgattcc atttcatcac
    38461 aagttcctcc tcatttactg cttcatcttt ttgctgtgtt tgaattgtaa aaccttgtga
    38521 aagatagaaa tgaatagctg attgattttt ttgatagact gtcaaagtca gtgttttatt
    38581 ggtttctttt atttttttca ttagttgcgt accgattctt tgttgccggt attccctttt
    38641 cacaaagatt cctgcgataa actgatcaat caccccagca aaaccaataa tttcttgatc
    38701 tatttctgct aagtaaatca ctgcatctgg taaagctttc ctaacagatt ctacttgatt
    38761 ctcccaataa gttgatggaa tgaattcatg agaatccaag ttagcatgca gccaaatcga
    38821 tagaacagat tccagttctt tggcagacaa ttttgttgtt gtgcggatca ttttttctct
    38881 ccttacttat tcattgattt taaaataaaa accatttttt tgaagctctt ttacaagttt
    38941 tcgcccctca aaaaagtata tcttctcttg ttttactttt ctaataccaa aagaaacagc
    39001 aactttagga tcatcagctg aaacgattcg ataagttcca ccaggcaatt gatccagctt
    39061 gactttccca tgatggtcgc tttgtactga aaacggcaca ccatttctag taagtgtttt
    39121 tttcttatgt ttcaaaatga atgaactacc atttaccggt ttccctgacg aatcactaat
    39181 aataaatgaa aaatcaagca cttttttact taatctatac tgatagatta gtcgtccgat
    39241 aaacactaac agtatgacta cagctattat cgttcctgca agaataaacc attgccgcat
    39301 ggttctttcc tgatttcctt ttccttcttc tttttttacc gattcgttat aaggaatccg
    39361 atgtcctgtc actagcaaac gatgcgtgtt gatcatatac ggcgtacatg taagcaaggt
    39421 aactaagtct tctccttctg aaatcgttag aacagacgtg tcatctggca gtaccacttg
    39481 tatattttta acttgataag ccaatttctc ccccaaaaca gtcaaaataa acgtgtctcc
    39541 gttttctaaa cgatctaatt cggtaaataa ccgtcgatta ggtaaaccgc tgtgagcaga
    39601 gatcactgaa tgcgtcgaat ttccaccaag cgggaaagag gttccttgca agacgcctgc
    39661 tccattttca aggatcctac cattgagccg atcataaagt gaaatattta attggatctt
    39721 aggtatattg atacttccga tcagccattc ctctaattgg ctggatgttg tactttcatt
    39781 tctgttcttt tcattgaaag gatcagtacc aggattgaat ccttggtcag ttaatcgttg
    39841 gtttttctcc tccattttct ttcgctgcac ttcaatttca gctgcggtcc gtttttgtac
    39901 ttgttcgata cgtttttgat caataaaact atttaaagaa tccacataaa atggatataa
    39961 agcgatcagt aaccctacga cgatacatat taataaaaac aaacgaaaca aaagtcgacg
    40021 agactgtttt tgcttactct gcttcacatg tgtcctccct tgcaagtttt tttgttcttt
    40081 cttttattat atgggttcag gaaaaaaata gaaaatgaaa gccgatgagg ttgtgaaaaa
    40141 gctgtcctgc atcaagtaat aagtacagcc caaaaaaata gctactcata ttttttgttg
    40201 ggttgggctt attaccgcag atgcaagctt ttgaacaccg tttaaggaag aggttgtgaa
    40261 aactgcgtta tgctttgagt aataagagcg ctagtcagaa aatagcttct catattttct
    40321 aggctagtga gcttattacc gagaagcagc tgattgaaca ccgtttaccg agaggtcatg
    40381 aaaaagctac tttgtttcga gtattaagaa aaattctgtt tcaaaacaag gagatgcaac
    40441 aaaacttatg tcgcatcctc tctccttaga actttcactt atgtttttct tgtaaaattc
    40501 ataaatattt tcatgaattt tctaatttct tgcctacctc tcgcatagga tatatgatga
    40561 atttatctaa agtttgcaaa ggagttcgac aattgaaaaa atatggccca tttttagcaa
    40621 tttttttcat tgctttggca tttctcatgc ctcatttatt cacacataaa ctaattttgg
    40681 gtgctgatgc cccattccat tacaatcggt tctatgatgc cgcgcaacaa attaaatatg
    40741 gggatttcca ttattttcct tccctttatg gattccagca aagtggcagg atcgtgaatg
    40801 ccgtttacgg cccatttttc gcttatttac aaggattgat cgtgttgctt gcaggtagct
    40861 ggtttcatta tcagattctt tcaaatttca ttctttatct tatttcagga ttttctatgc
    40921 tgattttact gagatatgtc aatgttcgaa attgggtaag tgtaccagta gccgttttat
    40981 tcatgagtac gtattctatt caatactggt ctatcaacca aggattcact agctggggga
    41041 cttgttttta tcctttatgt atgatcccta ttgctgattt cgtccttcat aaaaagttcc
    41101 ctgttatcaa agtcgctgtc tcagtgggac ttatgacaca gatccattta ctgtcttcga
    41161 tcatgttagc tttgatgtat atcccttttt atctttatta cttttttaac cagactgaaa
    41221 aaggaaaagc actgcttcaa ctgattaagt cggtcttgct ttattttgtt ctgacagcaa
    41281 atatttgggc aggattagct attgtttaca gtgggaataa gattcttcct ccctttgtta
    41341 acagagaaat gagtcaaaag gcgatagatc tggatggcag ttattggctc cattacccta
    41401 aggcctttcc tatattgata ttatcaggtt ttttgctttt tattttcttt caacaaaaga
    41461 acaccttatt ccaaaaaatc gtgttgtaca caagtcttgt tttctttttt ctttctacta
    41521 gcttgattcc atggacgaca ttgatcgaaa aaaatgtgcc ttttattagt ttgatccagt
    41581 ttccatttcg atttttcgtg ccatttacgc tattgcttct actttacctt gccctttcac
    41641 tgaaccagtg gtctgaacaa aagtggttcc gtcttttaag tatatttggc attcttattt
    41701 tttcagcaca gacgatccag aacttatacc agcatctgga aaagtgggaa aatgaaacat
    41761 ttgtcagtcg acatacttat ctattcgata cgccggaaga agcaaggaaa acattcttca
    41821 gcaaagatat gtctaccagc ttgttcgttt tccaaaaaac cacacctgac tatctgccaa
    41881 tctataagga gacaaaagac aataaatacg accggtataa cgaagaaata ctagaaaacg
    41941 aaacaacttt tataaaaaca catccaggcg gtcttttgac aatcaagtgg aaaaacactg
    42001 gggacaaaac tgttcatatc cctgttatcg tctacgatcg gactgtgcta cagcaaaatg
    42061 gaaaaacatt gactgattat gaagtaacag atatcgggac cccaatcgtg aagcagcaaa
    42121 aaggaatcaa cgagctcacg cttcattatc aaacgccaat ctatttctat ttcattcttt
    42181 ctcttacttt gattggctgg tttaccttgc tatgtttatt tatttatcat agatacaagc
    42241 ttttacgtgc ttaggcaaaa gggataaata catccgatca aaaaactctc caaacggtat
    42301 aatcgtttgg agagttttat tttaatcagt ttttttatgt tatatgttat attttttatt
    42361 cgttcacatc taattcgatt tccaccccgt agtgatcact gatgattgga ctatcgatcc
    42421 catcaaaaat ccgttgatat tttttaacct gcattccttc agggacgaaa ataaaatcta
    42481 tacgcaattt ttctgtattt tgttcccaac catctatttt cttttccaca gtagctgctt
    42541 ttcctttttc attcgcgaca acatacgaat cttgaagaag aaggcaactt tctcttacag
    42601 tataataacc ttgagagtct actggattat tgaaatcacc taggaaaaaa agtggtacgc
    42661 gagtttccaa aaagtagttt tccaagtttt tccactcaaa ataaaagcca ctttttttat
    42721 ctgtccacca agaaaagtgg cagctcgaga caaaaatgtc ctgatcatct atctttgttt
    42781 tcccaatcaa gatcttgcgt gtctgataat cttctttctt ttgaaattgg gagacggtaa
    42841 ggacctgact ttccaatgtt tttttcgtaa gcagtgcatt tccttcttca tatttatcat
    42901 aaccgatgtg gctcatttcc caactccaaa aatactcttt tccgtgttcc tttaaaagct
    42961 gaactaaacg gtaggcaaaa ttatctttac ggataggtac ttgattcttt accggacaga
    43021 acttcattag cttcgcaggt tctacttctt cagattccag taattggttg atttcttgta
    43081 aagcaatcac ttcataatct tctaacagga tcttatctgc taattcttgc aattttttct
    43141 ctggttctgg ctcaagccag ctatgcgtgt tgagtgtcat gaatttcatt ggttttctcc
    43201 ttgtcttcat ttcgaaacaa aagggttgtg acaaaatttt tgtcacaacc tctccagcaa
    43261 atagtgttct cctgctaact cctcagtaat aagctcaatg gaccaggagc tattttttgt
    43321 ttggctgttt ttatcacttg gtgcagggca gctttttcac gacctctcca ctaaacagta
    43381 ttcaaactgc tgcttctcgg taataagccc aaccaaacga aaaataggag gagctatttt
    43441 tgtttggctg ttcttatgac ttgatgcagg acagcttttt cacaacctct ccttacattt
    43501 taatggagcc gatcacttta ccagctgtca ctgtacctaa ttgcttgatc actacttctt
    43561 ctactttatc gtttgtaaat acgatcatga tcgttggatc tttttcttcg ttttggatca
    43621 catcaagatc catctcagct aatttcgttc ctgttcctac ttcttggcct tctttgacag
    43681 caatctcaaa agctggctga ttcatttgga ctgtatcgat tcccatatgg atcaaaactt
    43741 cgataccatc tttcgtttcc agcccaattg catgtttgct agggaaaata cttgtcactt
    43801 ttccagcgat cggcgcaaca acttctcttg atgttggaat aacagcaaag ccgtcaccca
    43861 tcattttttg tgagaatacc ggatctttta cttcagataa aggaatcact tctccagaag
    43921 ctgcggaaac tagttcttgt tctataccta agtattgctt actacctgct tgtccatttc
    43981 ctgtagaaac catttctggc tctggaatct ctgctcctga ttgcagcaga tcttcgatat
    44041 ctgatttcaa gacatctgct tttggtccat aaactgcttg gactccattg tctttgacga
    44101 tcaatcccat cgcccctgct cgtttccagg cttcttcagt ccctactttt tctcgatcat
    44161 ttacacttac gcgtaaccga gtcatacaag catcgacatc tttgatattt tcttttcctc
    44221 ccagcaaatg aatgatctgg accacttgct gatctgctgt tcctgttccg ctgttagata
    44281 caacggtttc ttcactgtca ttgtcgtaat ttccgttacg tcccggtgta gcaaagttga
    44341 attttttgat caagaaattt gctaagaaat acgtaacaac accaaaagcg atcacacaca
    44401 acacgaagtt gataagatct ccacctagac ccgctttgat agctaacggt gtccgagtca
    44461 gcaattcgat attcccaaat gaatggaccc gcaatggcaa gatatctgcc atcgcaaatg
    44521 cagccccttg gatcactgaa taaatgacat ataatggcac agcagcaaac ataaacatga
    44581 actccaatgg ttctgttaca cctgttagaa agacagccaa cgctgctgaa aaatacattg
    44641 atttatatct tgctttctta tcaggatcga cattacgata catcgcaaaa gccattccca
    44701 tcaagatacc tgaagaacca atcatttgtc ctactttgaa acgagccggc gtccagttat
    44761 gcaacacaaa ctcatattgc gacatatccc ctgcaccttt aagattcact aaatcagtgg
    44821 cccaagccaa ccataacgga tcttgcccaa atacttgtgt ccccgcctgt gcgcctgata
    44881 aaatctcata cgatccgcca agctgtgtat agttgatagg aatcgtcagc atatgatgca
    44941 atccaaatgg caatagtaaa cgttctaatg ttccaaataa aaacggtgct agaatcggtg
    45001 cgctttcttg tgattctgca atccataaac caaaattatt gattccagcc tgtacgtttg
    45061 gccacaccac agcaagaata aatgccacga ttgttgacca taagataaca acaaacggaa
    45121 caaagcgctt tccattgaaa aatgacaaag catccggcaa ttttctataa ttatagtact
    45181 tattataagc cattgccccg acaaatccag cgatgatccc tacgaatact cccatattca
    45241 aagctggtgc ttccaataca cttgtaaaaa atcctttaac catgatcttc gtaccgaaca
    45301 gagtgtgggt aaatgcatct tcattcgcaa gcatgtcact tgtgacacca aagatagccc
    45361 cagtgatccg attgattaaa ataaatgaga tcccagctgc aaatgctccg cctgctcttt
    45421 cttttgccca acttcctcct attgctaaag caaataaaat atgaagatta ccaataattg
    45481 cccaaccaat attttcaatt actccgcccg ttgtgacaag cggcgtccaa tcaggattga
    45541 tcaagggaat tgatttccct atactgatca tcaacccagc tgccggcata actgctacca
    45601 caaccattaa agcctttcca aatttttgcc aaaactcaaa actaaatatc tttttcattc
    45661 cgtttagctc ctttacgcaa tcggtttcgt taaacgtatt atagcgtgcg ttttcttttt
    45721 tgtaaatgct ttatttttta tttttctgtc tataccattc tataaaacct ataatacgtg
    45781 tgttcccttc tataattttc tcctaaaaat ttattttttt aagctttttt ctatgaaata
    45841 ttttcttttg tctattgact tgtgcaatcg gttgcgttta ttatgaacgt ataaaacagc
    45901 tcattaggag gagaaaaatg aaacagatca aacgactatt tgctattgat ccatggaaaa
    45961 tcagcacgac acaattagat aaaaaaaatc ttcgactgca agaatcttta acaagtattg
    46021 gaaacggtta tatggggatg cgcgggaact ttgaagaaac ttactcaggg gaccaccatc
    46081 aaggtactta tttggcgggt gtctggtatc ccgataagac acgtgtcggc tggtggaaaa
    46141 atggttatcc agaatacttt ggaaaagtga tcaacgcctt gaactttatc gcgatagata
    46201 tttcgatcaa cgatcagctg atcgacttgg cttctttgga accagaagac ttttactggg
    46261 aattagatat gaaaaatggt gtattatctc gtacattcac aatcactact tctactaata
    46321 aagtacgcat ttccttcgaa cgttttctga gcattgtcaa aaaagaatca gcttatatct
    46381 atttaactat agaaatgctt gaaggtagcg gaacagtcaa actcgtatca aaattggatg
    46441 gaaatgttca aaacgaagac agcaactatg atgaacattt ttggaatgag attgatcgtg
    46501 gaactataga agaaatcggc tatttgacga ctaaaactat tccaaacaac tttgggattg
    46561 aacaatttac tgttactgca gcaatgcgcc atttcgttaa tggaaaatca gtcatccctg
    46621 actatcacga agatacttta gcattacatg gttgcttgtc tgcagaatta tctcaaggtg
    46681 agacatggtc agtggaaaaa gaaattatcg ttcttactag tagagatatt ccagaagcgc
    46741 agcaagcaga aaaagctgtc tcagaattaa cgaaccagac aaacaattat atccaagcaa
    46801 aagaagagca aacagcggct tgggcagaac gatggaagct tgccgatgtg gtcatcgaag
    46861 gagacgaaga agcacaacaa ggtattcgat tcaatttgtt ccaactattc tctacttact
    46921 acggcgaaga tgaacgattg aatatcggcc ccaaaggatt cacaggagaa aaatacggcg
    46981 gagccactta ctgggataca gaagcgtatg ctgtccctct ttatcttgct ttagccaaac
    47041 ctgaagtaac taagaatctg ctgaaatatc ggcataatca actgccgcaa gcaatccaca
    47101 acgctcagca acaaggatta aaaggcgcgc tttatcctat ggtcaccttc actggtgtcg
    47161 aatgccataa cgagtgggaa atcacattcg aggagattca ccgaaatggc gcgattgcct
    47221 atgcaatcta caattatacg aattacaccg gcgatacgga atatttgaaa aatgaaggac
    47281 tggaagtttt agcagaaatc gcacgcttct gggcagaccg tgtccatttt tcaaaacgag
    47341 caaataaata catgatccac ggtgtgaccg gcccaaacga atatgagaac aatatcaata
    47401 acaattggta tacaaatacg atcgcagctt gggtcttgcg ttacacgcga gaaaattatt
    47461 taacttatca aaaagaagct gctatcacta tcagcgaaga agaactagcc aaatggaaag
    47521 atatcgcaga gaacatgtac ttcccagttg acgaagaatt aggaatcttt gtccagcatg
    47581 acacattctt agataaagat ctcatgcctg tatccgatat tcccacaagc gatcttcctc
    47641 tgaatcagca ttggtcttgg gacaaaatcc ttagatcttg cttcatcaag caggcagatg
    47701 tactacaggg gatttatttc ttcaatgata cttttacaaa agaagaaaag caaaaaaact
    47761 ttgatttcta tgaaccaatg actgtccatg agtcttccct ttcgccaagt atccattcga
    47821 ttttagcagc agaattagga atggaaagca aagctgtaga aatgtaccag cgaacagctc
    47881 gcttggattt ggataattac aataacgaca cagaagacgg cttgcacatc acttccatga
    47941 ctggtagctg gttgtcgatt gtccaaggat ttgctcaaat gaaaactgcc catgatcagt
    48001 tgagattcgc accatttctg ccaaaaactt ggaaagctta ttctttccat atcaattatc
    48061 gcggacgttt attgttcatc tcagtcacag atgaacaagt tactttcgag ttattagaag
    48121 gttctcctct agaaatttac gtctatgaac agtcttattc tttagcggat cgtctagaaa
    48181 taacgctaag aaaggaggaa gcaaatgttt aaaggggtat tgtttgattt agacggtgtc
    48241 attaccgata ctgctgaatt ccattatcgt gcttggcgaa agcttggtca ggaaatcggc
    48301 attacgatcg accacacatt caacgaacag ctaaaaggcg tcagccgaga agactcactc
    48361 tctttgcttt tagcttatgg cggaaaagaa cactcttttt caaaggaaga atttgcagaa
    48421 ttagcgaaaa gaaaaaacga ttattattta gagatgatcc agacgatcga accaaaagat
    48481 gtcttccccg gggtcgtgcc tttactggat tctttaaaag aagaaaaaat caagattgct
    48541 cttgcttctg caagtaaaaa cgggccattc ctacttgaaa aaatgggtct tacaccttac
    48601 tttgatgcta ttgccgaccc ggcagaagca acaaacggaa aacctgcgcc agatatcttc
    48661 ctccttgcag caaaagctgt cggactaaaa gcagaagaat gtatcgggat cgaagacgcg
    48721 caagccggta tccaagccat cctctcaagt ggcgctcaac caattggcgt gggacgtgct
    48781 gaagaccttg gagaggagat cccgcttgtc cctgatacga cttttcttac gatcgattac
    48841 ttgaaagaaa agtggcatga ccatggataa tccagagatc tccgtcgtac cagttccaga
    48901 gactgaaata aagaaaatca cattgaagaa cgactactta gaagtcgttc ttctcaatta
    48961 cggtgcccgc ctgcaccaaa tcttcgcacc agacaaagaa ggaaaatcag aaaatgtttt
    49021 attgtcttac gatcgtttcg aagatgttct aacagacaaa agcttttttg gagcaactgt
    49081 cggacctgta gccggaagga tccgggatgc ttcttggggt gagcatagat tggagaaaaa
    49141 ctgcggatca caccatatcc acggtggcac gaaaggctgg tctttccaat tttgggaagt
    49201 agaagttttc aaaactccat catcaatagg tgtggtcttt tacttaaaag atgaattttc
    49261 tacctatcca ggaccaatca ctgctacgat cacttaccgt ttaacaaaaa acgaattaga
    49321 gatgacaacc tctgctagta gccttgttga aaccatctgc aatccgacca accatgccta
    49381 cttcaacctt tcaggaaatg gaacaagaga catctatgaa catcagttaa cggtcttttt
    49441 agatggtgtg cttgaattag atcaagaaaa actgcctact ggaaattgga caaaaaaaga
    49501 aaaactgcca atcgacttta gaaaatcccc aacactgcaa gagatccttg catgttatcc
    49561 agatggacta gatgatgtat ttcttttgca tcatcctagg ctttccaaaa cttccttaca
    49621 attattcgag aagcattctg gtcgccaaat gactatagca acttctaata aaagtatggt
    49681 attattttct acgactggat tcgaagctga tttctctgtc aatggaaaac agatgcattc
    49741 aaactacgga ttagcaatcg aaccgcaaga aatccctgat atcgttcatt tccccaaatt
    49801 tggatcgatc aacctccatc ctggtcaaga acggatcagt cagacgattt atcggttctc
    49861 tgcacaataa caagagaaag gtgtttttat catggctatt accgtaaaag atgtggcgaa
    49921 aaaagccggt gttgccacct cgaccgtctc tcgtgtcatc aacgatcatc ctagtatttc
    49981 cgagacaaca aagaagaaag tccgaaaaat tatggatgaa ctaggttatg ttcctaacat
    50041 gactgcccgc aatctaggaa aacgcatttc cagtgccatc ggcgtaatct taccccctct
    50101 tgattcaaaa gagcggatcg gtaacccatt ttatcttgag atcatggaag caatcaacga
    50161 agaagcgcgg aattatgata tgactacagc aatcgctact gctaaaaatt ttgaattgct
    50221 gttagagaac gtccagcgta tgcatttaca aaaacaagta gatggtttta ttctagtgta
    50281 ttcagatagt caagatactg tcattgatta tttataccaa aaccacatcc ctttcacttt
    50341 gatcggacag ccttatcatc atgagaacga aatcgtttat gtagataatg ataaccagct
    50401 tctaggtaaa caagcaacag aatttttgat ccagaatgga cataagaata tcctgtttgt
    50461 gacaaacacg actcatgaaa gtttgtattt cgaacgatat ttcggttatc aaaaagcaat
    50521 gatgatggct ggtcttcctg cgttatccag tgtagtacta gagcatccgg aggattatct
    50581 gtcctttgag aaaacgttga aagaaaacga agccacagca ttggtggtca ttgacgatat
    50641 cttcgccctt cgcacgatgc agttggcgca aatgtatggc tatgtcattc cagagacact
    50701 ctccgtcatt agcttcaaca actcgatctt ctcaacatta acacaccctt accttacaag
    50761 tatcgatatc gatatctccg aattaggacg tgtcgctatg caaaagctgc gcgaattgat
    50821 ccatgaagaa ttgagcagtg gcgtacgttt ggtcatccct catcgcttga tcaaaagaga
    50881 gacagtcgtt cctttagaaa acccatacta aatagctgac tcactaaata cgctgaccat
    50941 ttatcctatg gtcagctttt tatgtaaaag aagatactac ttctaacaca ttgtttatct
    51001 gtaaaaaaga gcgtgggaca aaagtaaaga acacttttgt ctcacgctct aaacacgtat
    51061 aaacggcgga agcagaagca actccttcgg aaataagctg aaattcacaa aaatttaaaa
    51121 agcaattttc ttgagtttct tcttatttct tggagttaaa cgcttctgtc ccagcctctt
    51181 ttttccttcc ttcaattttt tacacgtcga cgattcaata aaaaaccgcc taatattgta
    51241 aagacaggtg caagaatcga gaaaaaggcg aatggcaagt aatgcaacgc gctaactttc
    51301 atcgttccca taatgaatgt gccgctgact ccccacggta cgagagaatt gacggtcgca
    51361 cctgaatccg ctagtgttcg tgtcaaatag gtttttgata agccaacgtc atcaaaagaa
    51421 cgcttgaatg tttctcctgg aagaatgatg gacagatact gttctccaac gatcagattg
    51481 attccgatac agctcaaggc agtaaacccg actaaacgag aaggtcggtc catcttttct
    51541 tttaattctt gaacgatggt atcaacgatc agatatttga tcagtaaccc acctaatgcc
    51601 aatgcaagta aaatcaaact agcagaacct aacatactca tgatcccgcc tcgagaaagc
    51661 agttcatcta gctttggatc aggtgtattt gcgacataac cattcatcaa gatgtctgct
    51721 gcttttccga ccgtcaaact tttctcatgg ataaaagaaa gaacgagagc agctgtcgat
    51781 cccgctagta atgtagggat agccggaatt tttttgattg cccccccaaa taaaataact
    51841 agtggaatca atgtccaagg agagatccaa aagctcgctt tcatgttttg gatcatttca
    51901 ttgatactag ctagatcggc tgaatgactg ttatgtccta atatcgtata aaaaatcaac
    51961 gaaaggacga atgctgggaa atccgtataa cgcataccag cgatatgttc gaatagatta
    52021 actcctccaa tacccgctgc caagttggtc gtatctgata aaggcgagca gttattccct
    52081 aaaaaggcac cggaaacgac tgcgcctgta gtcattgcat cattgaatcc aagtaaatga
    52141 ccgatcccca aaaaagcaat tccaatcgtc gaaatcgttg taaatgaact gccgacagtc
    52201 actccgacaa ttgcacaaac aagaaatgct gtcggtaaaa agaaacgcac agaaacaagt
    52261 ttaaatccat aaaccataat cgtagggatg gttccagata aaatccatga agcaactaag
    52321 acaccaatca aaagaaaaat caggattgga atgatccctg gagtgattcc tttgatgatc
    52381 ccgtcatgga tctcatccca tgtgaacttt ttaaatctgc cataaaacaa caaacacatg
    52441 aaagctgcaa ggatcgggat atgtggcgag agctggaatc cgatgatcag tactcctagg
    52501 agtgccaaca acacgatcaa tacagcgata ctttctttta aagaaatatt tttattcatc
    52561 gtcgatctcc tatttcaaat gaaaaggccc tgccatgaaa aaactattca cttggcagga
    52621 cctcctacta aatcagcgac aaaacgtcgg ctgaaagact tattttttta tttttcttct
    52681 aaactttttt ctacctcaat cccccaagaa tctttcttga agtgattgat gatcaatgga
    52741 ataacgaaca tgaccactgt gatagctgct actaataatg catcactcaa tgtcgctgta
    52801 cctaatgtag caaatacgac aacgatgata gagaagatca gcatgcagct gactacccaa
    52861 gctaatccgt ttccgttttt accaattcgg taaggacgtt cgaattctgg atgtttctta
    52921 cgcattttaa gcaatgaaac agcaatcaaa atgtacacga tacaataaat aacagttgta
    52981 gcatttgtaa gtgtcaagaa tacagcactt acgtcatcca ttacaccata aagcaaagca
    53041 aataatgaaa taacgattga ttgtgttaga acgacatttc tagatacgcc gtatttgttt
    53101 tctttatgga atccgaattt tggtggaagg aatccttcac gagctacttg gatgattgtt
    53161 tttgatggtc cagtaaccca agctgataat tgtaaaagca caccaataaa taccatgaag
    53221 ctgaagatat ttccgatcac ttctggtaag cctaggattt gacagtcaat caagataggc
    53281 tgcgtgatat ttgctaattc catttttcca tctggtacga catttgctac aagcatcgca
    53341 ttgatgacat tcaataaaac taatccgatc aaagcgataa atacgccttt tgtataattt
    53401 tttgttgcgt ctttcaaacg aggcatgtaa acagaactca tttcgatccc aacaaaaata
    53461 aatgtgatac cagctaagta tttcaatgaa tcaatatgtt ccaagtcagg gaaagctttt
    53521 gaccatgaaa agtcacctag atagccgttt gagactagtc cgactttgaa ggctgccaaa
    53581 acacctaaaa cgaacatgat gactactggg atatataccc ctagccatac accgatgttc
    53641 ccgccgactt ttgccatatc gaatttcaag ttcaagatcg tgatgatcca gtagataact
    53701 aaaatacaac ctaaaacgaa ccagtgatta ttgccaagtt ctacattacc aaatgtgttt
    53761 cctaacaatg gtcctaaagt agaagcgacc attaccatac ctgggaacat ttgcacccat
    53821 aatagccatg caacgacaaa tccccatttg ctgcccagtg ctgtttttac ccataactga
    53881 ggaccgcctt cttgaggaag catcgtggaa agctcaccgg aaaccattga tatcggaccg
    53941 gcaaaaaaca aaactgcaaa aattgaataa aaaatcaatg tccaaccgac tgcggctaac
    54001 gtaggaatac tccgaaccgt tgcacacagt gccattgtca gaccgataaa ggtcccaaga
    54061 cccattttac ttacttcaga tttactcacc gttgacactc tccttgattt tttggataaa
    54121 ataacggtgt ctttgaagta gtttcagcaa taaacgaaac aattcagcga atatttgagg
    54181 ggattctttg agtttattgc ttgaagggtt tcttcaaaga caacctcaaa acaaagggat
    54241 cgaagagctt aggtctcccc ttgctcttca gatccaaaca tgcgtcagaa acagttagta
    54301 ttcaagctgt tttctaacat gattaccttg cttattttgc ttcgcttgcc aataattggt
    54361 ctgcgtagat tttttccaat ttttcttgaa gagctgcttt gattttttca gcatattctt
    54421 caaagtgttc ttctttgttc atgtatggtg tcattacgct ggcacgcaat acagttactt
    54481 ttccggcacg gttccattct tcatctgaga atcctagttg gttcacaaat tgtaatgggc
    54541 tgttgccata gtctgggata gcaaagtcag tatgtgaagt taagaactca ttaccgtaaa
    54601 tgcttccttt cacgtatgaa gaataatcat atacgtcatg gttcaattta ttcattgcaa
    54661 ctaagtcatc gttgcctttt tctttgaata catagtctac catattgaaa tctggataag
    54721 ttaatggatg aacttcgatt tctttgtctc ctactttaaa tgacaagtca ttcaagaagt
    54781 tgtagaaacg atgtgcacct tcgattgatg cacccattaa tttaccatat cctgtgacat
    54841 tcaaaggtaa gacatggtgt gctgcccaaa cgctggctgc tgttgcccct gcttttgaac
    54901 cttccaagat ataagcccca agtaatgctg ggatatctgc gcctttttca aatacatatg
    54961 tcgcaaagta agagataacg tctctcatgc ggatatcttt gatgacgata ccaccggcag
    55021 aatatggaac atagcccatt ttatgtgggt caatcgttac agattctgct tcttcgattg
    55081 ctttatatgc actgtgtact tcttctaaga tataatcttt gttttctgta aagacattgt
    55141 atttgtaatg aacatctttt aaatcttcaa atggaatgaa gttgttgtct tcgtctaaga
    55201 aaatcgcacg gccgtatccg ccataagcag catctacgtg taagtagaag taaataccgt
    55261 ctttttctaa tacgcgacgc aatgcaacga ttttatcgat accgtcgatt gctccttctt
    55321 ctgttgatcc tacaacaccg actacaccta ggattggtgt tttttcagct gctagaccac
    55381 gaacgatttt ttcaagttcg ttgatgtcca tgcgatagtt gtggtcaact ggcactggaa
    55441 tcacttggtc taaaccgata ccgatgatgt cggcagcttt tagccatgaa tagtgtttag
    55501 tttgtggaac caaccatttt cctaattttt ctaaatgttt tccgctacgt gctgagtgag
    55561 ctttgatttc gtcgattttt tctgggacgc tgtctaacag attcatgatt tcttctgttg
    55621 acaagttcat taattcccaa tcgctttttc cagcaactag ttcaggtgtc acttctttca
    55681 ttgcaagcgg caatgatttg atgttgcggg cataccaaag tccttctaag tttgctaaag
    55741 aaccatcagc aacgatgtgg ccccagccat ctttatagct cattaatttt gcaaattcca
    55801 ttcctacttc ttcttccatt tggcttgttg caggagaaga ttcataggca acgttattac
    55861 cattccatag catagcaaaa ttgtacgcta gtaaagatgg catcaatgtt tcagagttca
    55921 tatgacccca gtaacgtccg gcattatgcc aaggaacgga atgggtacgc atccgcgctg
    55981 aaatttctga tagaacatcc tttgttttat tcacagtgtg ttcaaaacta gcactgcttt
    56041 tttcttctgg cgtaataata ggcatgtctt gaggcatgta gttttgacgc cagcctaaat
    56101 gttcatccac caattcattc aacaaagctt tatagatttg gccgttctca gctttgtccc
    56161 caatgaatag ggcatttagg tttagatctt tcgacaatga ttcactcata gtgaaaccct
    56221 cctaaaaaaa tatttaaatt ttgtcgagcc ctacattaca cctgttcttc tattctgtaa
    56281 actaagtttt ggcctgattt ttaatcatat tttaatatgt atcaattatc cgaattgttc
    56341 acacttttga aataattaaa aaaaacgagg gaatttacaa atgtaaactc cctcgcaaag
    56401 attgtattaa cgacaaccag cgttctattt taggatgggt ttcaaaattg gaatgttgta
    56461 atagtatttc cctttttcaa ggtaaaaact tactaaattc taatcaatta ctttggccaa
    56521 aaagtaattt ttcttacctt ttcgaataac cacaaactta ccatcgaatt catcggatgg
    56581 atttatgaca aaatttaaat cggtaacgcg gtcaccgtta atacttatag ctccgtttga
    56641 aacatcttca cgtgcttgac gtttagatgg ttcaattttt gtggaaacaa gcagttccac
    56701 gatattttca ggtgtgcttg aaatttcaac gttcggcatt ttaccgaatc cttgcgcgat
    56761 ttcttccgca tttagttctt taatatttcc agagaacaat gcttgcgtta ttttttgcgc
    56821 ttctttcaag tcttcttcac tatgcacaaa tcttgtaact tcttctgcca aacggcgttg
    56881 tgcttcacgt ttctcaggtt ctgtctctac ttttttcgct aagtcttcga tttcttcttg
    56941 agacaagaaa gtaaagaatt tcaagtattt cactacatcg cgatcatctt gattcaacca
    57001 gaattggtag aactcaaatg gtgaagtttt cttcggatca agccaaacgg caccgcctgc
    57061 agtttttccg aatttcgttc cgtcagcctt cagcatcaat gggatcgtta aaccgaacgc
    57121 ttctgcttct ggtccttcta attttcggat taggtctaat ccagctgtga tatttcccca
    57181 ttggtctgct ccaccgattt gcaattgcac atcgtatgtt ttatgcagat gcaaaaagtc
    57241 gatagattgc aggatttggt aagtaaactc tgtaaatgag attcctactt ccaaacggct
    57301 ggcaacgata tcttttgcta acatcgtgtt gatgttgaag tttttaccgt agtctctcaa
    57361 aaattcaagt aaagagattt ttgacaacca gtcgtagttg ttcacaaatg tgatatttgc
    57421 atctttacca aacaattttc tcatttgatt ggaaagtgcg tccacgttat gttgcacttg
    57481 ttccatcgtt tgcaacacac gttctgtttt gcggccgctt gggtcgccga tcgttcctgt
    57541 tccgccgcca atcagaatat atggatgatg gcctgccaat tggaatcttt tcatcatcat
    57601 aaatggaatc aaatgtccga tatgcatcga atcaccagtt ggatcaacgc cgcaataaag
    57661 tgaaatgctc ttttcttcaa cgagctcgcg aagtctttct tcgtttgttt gctgattaat
    57721 ggcgtcgcgc caagttaatt catcaataat attcatttta ctgacctccg tgtagttttt
    57781 ttatgaaagc aggaacctgc tagcatatgt aattaattat ttcttcagga taggatagga
    57841 aataaaaaaa gtcccttggc atataagcca agggacgaaa tctcgcggta ccacccaatt
    57901 tgtatgtcta gatatccaac atacctctcg aacatttaac gctgtcgcgt ggcaatcact
    57961 gccaaagact cctgaaatgt aattcgcttt aaagcatgta ctggtttgca gcgaccacca
    58021 gctttctgaa acattggctt taacaactac ttcgtttcga tcttcgtctt gttattatta
    58081 atatgtgtct atcatagagc gcaacttttt ctttgtcaac agaaaaagga tatttttttt
    58141 aaattcctca ttttttcttt tttgaatccg ctctaattcc gaacatttta ttttcaatta
    58201 ttgttaaaag aaataacttt ttctgtattt tttctgcaat ttatcgagaa gtcactttac
    58261 tttgcctctt attctttctt cgttacaata aggaatggga caagtaaaaa aatgaaaaag
    58321 caagggacga ggtatatgga aaaaaagcaa aaaattattt taggagccac ttctgcttta
    58381 actatcgtta ttttaattct aagtttgttt tttgtcatcc gatcatctac aaaaaaagaa
    58441 ccaatcattc ctgaaaaaaa aataacagaa aaagcaaaag aaccgacaga tgataagcaa
    58501 caactagtta ctcaagcaaa aaatctggct caaagctacg attatgacca agcgattgcg
    58561 ttattggaaa aagatagtaa gaacggatct actgaaacac aacagcttct tcaaacacta
    58621 aaaaaggaga aagaacaact gatcgactgg tctgatccta ctcagatctc tcatgtcttt
    58681 ttccacagct tgatcgtgga cccgcaaaaa gccttccact ctcaacaggc acaaggatac
    58741 aaagattata tggtgactgt tgaagaattc aaccgttcga tcgaacaact ttatcaaaat
    58801 gattttgttt tagttaattt gaatgatttg atccaaaaag acgaacaagg aaatctttcc
    58861 tttaacgggc ttgcgctacc tgaaggaaaa aaaccattgg ttctttcaca agatgatgtc
    58921 agctattatg aatatatgga taattccggt tttcctagcc gattggtcgt atcaaataac
    58981 aatgaaatca aaaatgtcta taaagagaaa gataaagaag aaatcggtga ctttgacatg
    59041 gttcctctga tcgatgcctt tgtcaagaaa catcctgatt tttcttatcg aggcgcaaaa
    59101 ggtaccttgg ccctgacagg ttacaacgga gttttaggtt atcgaacatc aaaatctcaa
    59161 tatggagaca atgaaaaaac aaaaaaagag attaaagaag ctaaaaaagt ggcggaacag
    59221 ttgaagaaag acggctggag ctttgcttcc catacatggg gtcacttgaa tatgactcaa
    59281 gcttcactag aagatgtaaa aaaagacaat gaattgtggc agcaagaagt tgcacctatc
    59341 ctaggaaaaa caaatattct gatttatcca tttggtgcag acatcagcga ctggcagcct
    59401 tattcagcag aaaatcaaaa atttgcttac ttgaagagtc aaggtttcga tattttctgt
    59461 aatgtcgatg cttctacacc agcttgggga caattaggta cggatttcta tcgaaatgct
    59521 cggatcaata tcgatggcat tcgttttcaa tctgatttag acggaaaaaa tcctattctt
    59581 gatccattca tcaatgtcca tgatgtctat gacaaagaag cacgcgaatc tgcttgattt
    59641 tacgtcattt atgaaccaaa aaagccgaac tgacatttta tcgtcagttt cggctttttt
    59701 atgctttatt tcttcttcgg tgcgattccc ttgatcagga cttctgtcca ttctgctgta
    59761 tatggaagca gttttgcgta tatctccggc ttagaaattc cttctaccat tgcttgaaaa
    59821 tagaggatca agaactcatc cgaatatttc aaatccactt ttccttcttt ccgccctcga
    59881 tggaaaagat caagcatgat actgaaactt tcttgcgtat acgcatccat cgcgtcagaa
    59941 aattcttttt tttctttttt tgtatagtat gtcatcaaat cgatataaaa ttgtttgttc
    60001 actcgattga gataacggat tttgttttca ctcatggcaa tcagtgtttc ttcaaatgga
    60061 agattttccg caatcaacgc tttcgcttct tgccctaaat cattcataaa tgcaaaaaat
    60121 acttcataaa tcagcccttc cttgctgcca aaatatttaa aaatcgtcgc tttacttacc
    60181 tgagcgttct cagctacctt atccattgtc actccagcgg ttcctatgtc tgtgttcatc
    60241 aagtcaaaag ctgcttgtaa aatctctttc tttttctctt gtgctctctt ttcaaaaccg
    60301 ttcatttgta gagcctcccg taattttaaa cttttataat atatatagtt caaatttatt
    60361 ctgaggttta ttataactat ctattgagaa agtatcaagc tagcaattcc ttgtttatga
    60421 attcattgac agaaatttat aaaaagaata ttatgtacta aaataataaa aaaagtttta
    60481 taaaaaggta taaaaccttt ttattaaact atttaatctt gtttagtata tatttttaga
    60541 aaaaggagtg gggtttttat ggcagaaatc gtcaaagtca cacatttgaa aaagagcttt
    60601 ggtcgtttcg aagctttaaa agatgtctct ttcaccgtac attcaggtga agtcgttgga
    60661 tttatcggac caaatggttc tggaaaatcc acgacgattc ggacactttt agggattata
    60721 aaaaaagacg gcggaacggc aacgattttt gggcaagatg tatgggaaga tagtttatct
    60781 atccatgaac gtctttctta tgttccaggc gatatctctt tgtggggaaa tttgactgga
    60841 ggagcgatca tcgatctctt catgaagctt catggaaaag ggagtgctca aaaaaaagat
    60901 gaactgattc aacgtttctc tcttgatcct aagaaaaaag caaaaaacta ttcaaaagga
    60961 aatcgccaaa aagtgggctt gattgctgct ttggctgttg attcggatct ctatttattt
    61021 gatgagccta cttctggttt agatcctttg atggaaacga ttttccaaga agaagttgaa
    61081 aaattgaaag aacagggcaa atccatccta ctttcttctc atattctcag tgaagtcgag
    61141 cgactagcgg ataaagtcgt gatcatacgc gaaggaacac tcgatgaaga aggaacactc
    61201 gatgaattgc gtcatttgac tcgttcgacc atcactatag aaacagaagc agagaatagt
    61261 cacttagcac aattgaacgg tgtccatgac tttgtgcaaa aaggtcacct cgctcaattt
    61321 gctgctgata acgaagcttt cgatgtgatt ttagctgaag cgtccaaatt aggtgtgaaa
    61381 aaatttgaat ctattccacc gactcttgag gatttattca tgagacatta tgaaggatga
    61441 ggaggaagcg aaatgactga taaattttca cgctggtcca cccttttttc tcaaaacctt
    61501 agccgtgact ggaaaaagat cctgatatgg ctagtcggtg tcactgcttt ttctggtggt
    61561 tttgtccctg cgtttgaaga attgacttcc ggacaaggat tagctggatt atacgaaacc
    61621 ttgcaaaacc cggcaatgat tgcaatggtc ggaccaactc cagcttcgaa tgctgctgag
    61681 tatactttag gagcgatgta tgcaaatgaa atgttgcttt tttgcagttt gtttgctgct
    61741 gtgatctctg ttttacacgt ggtgagccaa acgagaaaaa aagaagaact tggtctgatt
    61801 gaacttattc gttcctttcg agtcggacgt caagcaaact ctttagctgt catcgctgaa
    61861 agtattctga tcaatttgct tttagcaata tcgatcagct gtacgatgat ttttttccaa
    61921 gcggattcga tcactgcaga aggtgcttgg ctttttgggc tatctgtagg tagtatgggg
    61981 attttgggga gtgccgttgc actgtttgct gcacaactga tgccaagttc agccagttcg
    62041 aatggtctgt ctttagcgtt tttaggtgga ctttaccttc tacgagcaat aacagatgta
    62101 gctgattcct ccctttcgat gtggaatcct ttaggctggt cttatttgac ctatccattt
    62161 acaactaaca actggattcc tttgctttat ttgtttttgt tcagtctaat cttgataatc
    62221 agttcatttg ttttagagga acatcgagat ttgaacaccg gctatatccc cgaacgtgaa
    62281 ggaaaaccgt atgctaaacg ttctctttta tccttgcgtg gtttattatt ctatctaaat
    62341 aaagggatga caatcagttg gcttatcact tttggtttga tgggggcggc atacggctct
    62401 atctacggga atatgcaaca gtttttagaa agtaacgact taatgaaaca gatgtttatc
    62461 caatctggcg tctcaattga aaaaaacttt acaagcacga tcatggtagt cttgatttgt
    62521 ctagctgcta ttttaccaat tgctagcatc aatcgtttat ttacagaaga aacccacgga
    62581 cgtatgaatc agctgttcgc aacaaaaatt tctaggaacc aactttattg gaccaatatg
    62641 ttactagcta ttctatttgc tatattggca atcctgatta gttctggtgc actagggctt
    62701 tctgctttgg cttcgatgaa ggatgcgaaa gacatggatc tattgatgtt tcttaaagcc
    62761 gggttcaatt tcctgcctgc cgttttagtg tttatcggaa ttagtggctt tctattcgga
    62821 tggcttcctc gaatcggtaa acttgcttat atctacttag cttactcctt tgcactcaat
    62881 tactttggcg gaattttgga tttaccagaa tggttttcca aaacagctgt ccctagctgg
    62941 gttccacgga tgccaaacga ttcttttgat ctttccgtgt tccttacgtt atcatgtatc
    63001 agccttgcac tgttcgtcct tggttctatt ggttataggc gaagagactt actagaagga
    63061 taataaaaaa gcatgtacaa tttcatgcta gcctccaaat ctgggtcaaa aatccaacat
    63121 ttggaggtca tttttttatt tacaagtctt ctaactgctc tttatcaatg atccagactt
    63181 ctcgattctt tctttttaca taaccattct cctctaataa tttaaatttt ctagataaag
    63241 tttcgggggt cgtaccgata aatgcagcaa gttctttcat tttcattggc aggaaaaagt
    63301 gatccttccc tgtcgcttta gctaagtcaa gcagatagag agcgactcgt tcttctactt
    63361 tttccatcat caaaaaagtt gtctgctgct gtacttttgt taatttctca acgttgattg
    63421 ctaaaagttt cagactaagg gcgggataat gcagtaagag ttccgagaaa tctttttgtc
    63481 tcaatatgca aatttccgtt ttttctagtg cttcgccaaa taaagactca tttggaacgc
    63541 ctagcaactg gctctctccc tcatatccgc ccggctctat tactcgtaaa agctgttcct
    63601 ttccgctagc agataattga tacactttca tactgccgga ggccacgatc actaattgag
    63661 gttctccatt cggcgcaaga atctgttctc ctttttccac atagtgatgt ttgacaagtg
    63721 cgtgtacttt ttcttgatct tgctgtacta agtgattgaa caaaggaaca aatgaaacac
    63781 ataaatgatc atgactcata atctctcctc cttctaaaca gctatttcta ataaagaaac
    63841 ataacttccc ttattccaac tgataatttt cttttatcat agcataaacg tcaagcgaac
    63901 cagataccag caaatagagt ggatttcttt ttgtcccttg ctttattttc cttcttttga
    63961 gaccttaagt aattgattcc tatcaatttt ttaaatattt actttttgaa taatcaaaaa
    64021 caaaccttca ctcgcaagcc gagagtaagg tttgtttttc gcattgctta tttcgtgttg
    64081 tctattgaaa tttttccgca cctagctttt gatatagtgg tgctagttct tgtaaggttt
    64141 cagcggttat ttgctcaacg tgttcgattt cttgcggata gaagaatagt ttacccattt
    64201 gaaaggttcg gtctctcatc gcttttttca actcttcttg tttctttgta tcggacaaat
    64261 agtcagacaa agctaagtgg tcgtcaagtt catgttctgg ttgcggccat atgtaataat
    64321 ccttgatatc gactgttttg ctccactctt tcagtatcgc aagcaactgg ttatacgctg
    64381 caatgctacc atatcgttct tcgcttttat aatgttggta catcaaatag atttggtatt
    64441 gtttttgatt caacaaaact gctagacagg cattctcgtc ttgacgagat tcgcttcggt
    64501 acgcgctcca aaaatgactg cgtaaattcc agccattcgt ccagctttcg attttaggtt
    64561 tgctcatgcc gtacatatca ggcaaaagtg cagctgtctg gagctgaatc tctttccatt
    64621 tttgccagtg ttctttatat tctttcttga tttgttcaat cttatctgtt ggatggctct
    64681 ctttgagctg tttgaatgcg tagattggtc gatcaaacaa ctgataatct gattttccaa
    64741 gttccattgt ttcgcctctt tccgttatct tttgtattct acctgaattt tgcgatatgg
    64801 acaaatagag gttgtgaaaa agctgttctg catcaagtca taagaacagc caaacaaaaa
    64861 actgcgatga gcatcaccgc agttt
//
LOCUS       DAFLVO010000005        64420 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.005, whole genome shotgun sequence.
ACCESSION   DAFLVO010000005 DAFLVO010000000
VERSION     DAFLVO010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 64420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64420
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.005"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(10..588)
                     /locus_tag="L1U99_000342"
     CDS             complement(10..588)
                     /locus_tag="L1U99_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1210918.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(665..1195)
                     /locus_tag="L1U99_000343"
     CDS             complement(665..1195)
                     /locus_tag="L1U99_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBN1210919.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1199..2059)
                     /gene="rlmB"
                     /locus_tag="L1U99_000344"
     CDS             complement(1199..2059)
                     /gene="rlmB"
                     /locus_tag="L1U99_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBN1210920.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2052..2447)
                     /locus_tag="L1U99_000345"
     CDS             complement(2052..2447)
                     /locus_tag="L1U99_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBN1210921.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2444..3856)
                     /locus_tag="L1U99_000346"
     CDS             complement(2444..3856)
                     /locus_tag="L1U99_000346"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBN1210922.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(3853..4389)
                     /gene="cysE"
                     /locus_tag="L1U99_000347"
     CDS             complement(3853..4389)
                     /gene="cysE"
                     /locus_tag="L1U99_000347"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBN1210923.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(4475..4714)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(4711..6171)
                     /locus_tag="L1U99_000348"
     CDS             complement(4711..6171)
                     /locus_tag="L1U99_000348"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBN1210924.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(6341..7498)
                     /locus_tag="L1U99_000349"
     CDS             complement(6341..7498)
                     /locus_tag="L1U99_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBN1210925.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(7532..8902)
                     /gene="radA"
                     /locus_tag="L1U99_000350"
     CDS             complement(7532..8902)
                     /gene="radA"
                     /locus_tag="L1U99_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBN1210926.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(8965..9492)
                     /locus_tag="L1U99_000351"
     CDS             complement(8965..9492)
                     /locus_tag="L1U99_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBN1210927.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            9722..10528
                     /gene="proB"
                     /locus_tag="L1U99_000352"
     CDS             9722..10528
                     /gene="proB"
                     /locus_tag="L1U99_000352"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HBN1210928.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            10525..11772
                     /locus_tag="L1U99_000353"
     CDS             10525..11772
                     /locus_tag="L1U99_000353"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HBN1210929.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            11848..12192
                     /locus_tag="L1U99_000354"
     CDS             11848..12192
                     /locus_tag="L1U99_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210930.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(12309..12635)
                     /locus_tag="L1U99_000355"
     CDS             complement(12309..12635)
                     /locus_tag="L1U99_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210931.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(13250..14452)
                     /locus_tag="L1U99_000356"
     CDS             complement(13250..14452)
                     /locus_tag="L1U99_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1210932.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            14569..15084
                     /locus_tag="L1U99_000357"
     CDS             14569..15084
                     /locus_tag="L1U99_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBN1210933.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(15283..15729)
                     /locus_tag="L1U99_000358"
     CDS             complement(15283..15729)
                     /locus_tag="L1U99_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBN1210934.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(15776..17254)
                     /gene="msr(C)"
                     /locus_tag="L1U99_000359"
     CDS             complement(15776..17254)
                     /gene="msr(C)"
                     /locus_tag="L1U99_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBN1210935.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(17608..18237)
                     /locus_tag="L1U99_000360"
     CDS             complement(17608..18237)
                     /locus_tag="L1U99_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBN1210936.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(18221..18685)
                     /locus_tag="L1U99_000361"
     CDS             complement(18221..18685)
                     /locus_tag="L1U99_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1210937.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(19172..20440)
                     /locus_tag="L1U99_000362"
     CDS             complement(19172..20440)
                     /locus_tag="L1U99_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBN1210938.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(20671..21408)
                     /locus_tag="L1U99_000363"
     CDS             complement(20671..21408)
                     /locus_tag="L1U99_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1210939.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(21475..22044)
                     /locus_tag="L1U99_000364"
     CDS             complement(21475..22044)
                     /locus_tag="L1U99_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBN1210940.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            22172..23044
                     /locus_tag="L1U99_000365"
     CDS             22172..23044
                     /locus_tag="L1U99_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1210941.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            23386..24258
                     /locus_tag="L1U99_000366"
     CDS             23386..24258
                     /locus_tag="L1U99_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1210942.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            24255..26213
                     /locus_tag="L1U99_000367"
     CDS             24255..26213
                     /locus_tag="L1U99_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1210943.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(26545..27396)
                     /locus_tag="L1U99_000368"
     CDS             complement(26545..27396)
                     /locus_tag="L1U99_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1210944.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            27519..27986
                     /locus_tag="L1U99_000369"
     CDS             27519..27986
                     /locus_tag="L1U99_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBN1210945.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(28249..28731)
                     /locus_tag="L1U99_000370"
     CDS             complement(28249..28731)
                     /locus_tag="L1U99_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBN1210946.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(28831..29694)
                     /locus_tag="L1U99_000371"
     CDS             complement(28831..29694)
                     /locus_tag="L1U99_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBN1210947.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            30292..31167
                     /locus_tag="L1U99_000372"
     CDS             30292..31167
                     /locus_tag="L1U99_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210948.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(31312..31464)
                     /locus_tag="L1U99_000373"
                     /pseudo
     CDS             complement(31312..31464)
                     /locus_tag="L1U99_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(31732..33063)
                     /locus_tag="L1U99_000374"
     CDS             complement(31732..33063)
                     /locus_tag="L1U99_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1210949.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(33212..33925)
                     /locus_tag="L1U99_000375"
     CDS             complement(33212..33925)
                     /locus_tag="L1U99_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1210950.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            34100..35524
                     /locus_tag="L1U99_000376"
     CDS             34100..35524
                     /locus_tag="L1U99_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1210951.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            35823..36530
                     /locus_tag="L1U99_000377"
     CDS             35823..36530
                     /locus_tag="L1U99_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBN1210952.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            36517..36840
                     /locus_tag="L1U99_000378"
     CDS             36517..36840
                     /locus_tag="L1U99_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBN1210953.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(36929..37966)
                     /locus_tag="L1U99_000379"
     CDS             complement(36929..37966)
                     /locus_tag="L1U99_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBN1210954.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(38287..39270)
                     /locus_tag="L1U99_000380"
     CDS             complement(38287..39270)
                     /locus_tag="L1U99_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HBN1210955.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(39685..40455)
                     /locus_tag="L1U99_000381"
     CDS             complement(39685..40455)
                     /locus_tag="L1U99_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1210956.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(40448..41383)
                     /locus_tag="L1U99_000382"
     CDS             complement(40448..41383)
                     /locus_tag="L1U99_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1210957.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(41699..43348)
                     /locus_tag="L1U99_000383"
     CDS             complement(41699..43348)
                     /locus_tag="L1U99_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBN1210958.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(43465..46068)
                     /locus_tag="L1U99_000384"
     CDS             complement(43465..46068)
                     /locus_tag="L1U99_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBN1210959.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(46080..47129)
                     /locus_tag="L1U99_000385"
     CDS             complement(46080..47129)
                     /locus_tag="L1U99_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBN1210960.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(47155..47469)
                     /locus_tag="L1U99_000386"
     CDS             complement(47155..47469)
                     /locus_tag="L1U99_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBN1210961.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(47485..47931)
                     /locus_tag="L1U99_000387"
     CDS             complement(47485..47931)
                     /locus_tag="L1U99_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1210962.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(47932..49854)
                     /locus_tag="L1U99_000388"
     CDS             complement(47932..49854)
                     /locus_tag="L1U99_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBN1210963.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
     gene            complement(50066..50962)
                     /locus_tag="L1U99_000389"
     CDS             complement(50066..50962)
                     /locus_tag="L1U99_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1210964.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(50955..51635)
                     /locus_tag="L1U99_000390"
     CDS             complement(50955..51635)
                     /locus_tag="L1U99_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1210965.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(51636..52418)
                     /locus_tag="L1U99_000391"
     CDS             complement(51636..52418)
                     /locus_tag="L1U99_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1210966.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(52411..53328)
                     /locus_tag="L1U99_000392"
     CDS             complement(52411..53328)
                     /locus_tag="L1U99_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1210967.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(53492..53815)
                     /locus_tag="L1U99_000393"
     CDS             complement(53492..53815)
                     /locus_tag="L1U99_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210968.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
     gene            54603..57830
                     /gene="fss3"
                     /locus_tag="L1U99_000394"
     CDS             54603..57830
                     /gene="fss3"
                     /locus_tag="L1U99_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBN1210969.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            57943..58257
                     /locus_tag="L1U99_000395"
     CDS             57943..58257
                     /locus_tag="L1U99_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBN1210970.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            58270..58644
                     /locus_tag="L1U99_000396"
     CDS             58270..58644
                     /locus_tag="L1U99_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBN1210971.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            58654..58989
                     /locus_tag="L1U99_000397"
     CDS             58654..58989
                     /locus_tag="L1U99_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HBN1210972.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            59072..60412
                     /locus_tag="L1U99_000398"
     CDS             59072..60412
                     /locus_tag="L1U99_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBN1210973.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            60490..61164
                     /locus_tag="L1U99_000399"
     CDS             60490..61164
                     /locus_tag="L1U99_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBN1210974.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            61157..61321
                     /locus_tag="L1U99_000400"
     CDS             61157..61321
                     /locus_tag="L1U99_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210975.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            61397..62539
                     /gene="dcm"
                     /locus_tag="L1U99_000401"
                     /pseudo
     CDS             61397..62539
                     /gene="dcm"
                     /locus_tag="L1U99_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            62529..62819
                     /locus_tag="L1U99_000402"
     CDS             62529..62819
                     /locus_tag="L1U99_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210976.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            63078..64262
                     /locus_tag="L1U99_000403"
     CDS             63078..64262
                     /locus_tag="L1U99_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBN1210977.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            64259..64396
                     /locus_tag="L1U99_000404"
     CDS             64259..64396
                     /locus_tag="L1U99_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBN1210978.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
BASE COUNT        19279 a        12980 c        11706 g        20455 t
ORIGIN      
        1 ttttctaaat tattcctcat tataaaattt caagtgtttt tttattttga gttttactct
       61 cccgtaagcg ctcattactt gcttgtgatc cattgctaaa cattcagcca tgtctacaaa
      121 atcaacgcct tgcatataat aatgaaaaat tttagcttct atttttgaaa actggatttc
      181 gcaattttcg attgcttctt ttaataaaag atgctgaatt gctaaaggtt cttgcaatgt
      241 gatctctgct aaaaagtctg gtccttctgt ctctattttt tggtcgattg agacttcatc
      301 tttttgatca cgacgcttca gcgcgttctg cttcctcaac agagaataga tttgattgct
      361 tataacgctt ttataataac ttccaaagct aacacctttg cttttttcgt aagttctcaa
      421 tgcctgatat aaagcgatcc ttgcttcttg ttcccaatcc tcagaaacat aatttcttaa
      481 ataataggtg tttttcaaac gtagtaaaag tggaaaatat ttttgataca gggcagcaaa
      541 tgcttcttcg tcaccattac gtgcagcgcg caataactcc tcagacataa aataattcct
      601 ccataaattc gtttatggag gaatcttatc atcaatgatt catcgaactg attagaacga
      661 tatgttattt attttttctc attaaatcgt ccaatttttg ggacaatttt tttaactgct
      721 cttcattcca tggagaatta cgtcggaaat caataaaatg catatcttta ttttcttggg
      781 ctattgtttt ttccgttttt tttatcgtct tatataattc ataagcagaa gttcgtaatg
      841 ctccttggga aaagatcatc cactgttctg ctaaatcgct tgtcgccact gtcacttgtg
      901 tcaaacggtc attcagctga ccagcgattc tctcgatata actgtcagcc gtttcgtctt
      961 ctttcgtaaa aacaacatcc aactggtatt tcttataatt ttgttggatg cccggaacta
     1021 gttgggcatc gaagacaacg atgacttcca ttccttcata tttcgcataa tttgataaac
     1081 gatgtaaaag agcttctctt gcatccgcca ttttgtcctg ctttttaagc tggacaagtt
     1141 ccggccacga accaatcatg ttgtagccgt ctacaatcaa cagctgtttt ttcatggtct
     1201 actccccctg acgttgggaa aaagcctgat acataagcaa accagcagca acactggcat
     1261 ttaagctctg gacgtgcccg gtcatcggga tcgtcagcaa ttcatccatt tcttttttca
     1321 atcctggact cattcctttg ccttcattac caatgactaa agcaattgat cctttggcat
     1381 tccatttttg gaagtttgtg ccggtcatat ctgtgccaaa tacccaaaat cctgtttctt
     1441 tgagctgttg cacagcttgt accaaattcg tcacgcgtgc aacagggaca tgttcgactg
     1501 ccccagtgga agtctttgtt acgataggtg tgattccaac tgctcggtgt tttggtatga
     1561 tcacaccatc gacgccactt gcgtctgctg tccgtaaaat cgacccaaaa ttgtgtggat
     1621 cttcgatgct atccaaaatc aaaaagaagg ggtcttcttt tttctctttt gttcgttcaa
     1681 tcagttggtc aagggataaa tattcataag gtgtaatcgc aagaacgact ccttgatgca
     1741 cgccgtgatc gctcaaagtt tctaattttt gtttaggaac ccatttgact ggcacagctt
     1801 gttcacgtgc gatttctttc agttcttcta ctttttctcc tcgtgaatct tcttgaagaa
     1861 agagtttatt ccctcgccct tgttgtagcg cttctactgc ggcatggtgc ccaaagacga
     1921 aattatcttc taatgcttct tcattttgat cagaaactga ctgatttcgt ccagtttgct
     1981 ttttatttga atatctattt tgttttttgt cttcaaatcc acgtttcgat tgatgtttgt
     2041 ttgttctttc tttacccatt tttttcacca actttctgaa tacaccagcg gatcaattct
     2101 tccatccgct cggtttgttt tgtcaaatgc agatagccca tgagcgcttc gaaccctgtt
     2161 gcgacccgat acgtcgtaac atcagcattt tttgcgctcg tatggctttt agcatttctt
     2221 cctctgcgat aataaagttc ttcttcttct gtcaaaagat gttcttccag catttgctga
     2281 atcaaaaagg cttgtgcatt cgcagaaaca taattcgttg ccgcacgatg cagcttattg
     2341 ggttttgttt ctccttgatc aatcaggtgg tcacgaacat agatttcgta aatcgcatct
     2401 ccaacataag ccaaggctaa accgttcaat tgtgtgtaat ctctcatgct tctcttctcc
     2461 atcgggttcc ttgcggtgta tcttctaata agatcccttt ttctttcaac aaatcacgaa
     2521 tttcgtcgct tcggacaaaa tcacgattgc ttcttgcttg atttcgttct tcgatcaatt
     2581 gttcaatctc ttcatctaat aactcttctg ctgtaaataa aataccgaag atcgaaagcc
     2641 attgcgagaa taaagcttct ccttgtgcca agacagcggc agaaactttc ggctggtcta
     2701 gataagtgtt cagccactta gcaagctcat agaccactgt gatcccattt gctgcattaa
     2761 aatcatcgtc catttcttcg atgaatcgct gttctaaatt ttctaacaaa gcgattttat
     2821 ccgcatcatc tgccaaattc tctgaggcag tttcttggcg gaatttcaaa ttgtcaaacg
     2881 tattcttcag tcgttgtaaa ttggtggctg cttctttcat cgtcgtttca ctgtagcgga
     2941 tcggacgacg gtattgtgtg gtcgccatga agaaacgcaa gacttgtgga tcaacgtttt
     3001 tgatcatttc atgtacagtg atgaaattcc ctagagattt actcattttt tcatcgtctt
     3061 cgccaatcgt tacatagcca ttgtgcatcc agtaattagc gaattttttc cctgttttcg
     3121 cttcactttg tgcgatttca ttttcatgat gaggaaattc taaatcttgc ccgccaccat
     3181 ggatatcgat cgtttctcct aaatgttttg ttgccataac ggaacattca atatgccaac
     3241 cgggacgtcc tttgccccat ggtgaatccc aagaaatctc gccaggtttt gcttgtttcc
     3301 ataaagcgaa atctaatggg tcttcttttt gctgctgttc ttcccctgta cgctgacttg
     3361 ctccgacttc cagttcatcg atggattggt cacttaattt cccataattt tcaaatttac
     3421 gggtacggta atacacatca cctgaagatt cataagcata gcctttttca accaacactt
     3481 gaataaatgc taaaatatct ggcatatgat ccatgactct tggatgcagt gtagcaggtt
     3541 cgacattcaa cgctttcgta tcttcttcaa atgctcggat gaaacgatca gcaacttctg
     3601 gtgctgtaat acctaattcg tttgctgtac ggatgatttt atcgtctaca tccgtgaaat
     3661 tcgatacgaa atcgacttta tagcctcgat attcaaaata gcgtcgaatt gtatcgaaag
     3721 caatggtgct acgagcattt ccgatatgga tataattata cacagtcggt ccgcagacat
     3781 acataccgac atgtcccttt tgtataggga tgaattcttc tttttttctg gtcaatgtat
     3841 tgtagatttt tatcattctg atctcctcac tttttctcct ttgattcgaa cgacttttgc
     3901 tggtactcct accgctgtag cgtcgtctgg aacatctttc aacacaacgg cacctgcacc
     3961 gattttggcg ttttttccga tcgttaccgg tcctaatatc tgcgcattcg cagagagcat
     4021 ggctccttgt ttaacagttg ggtgtctttt acccgtttct tttcctgtgc cgcctaatgt
     4081 tacgccatgg aataaaatca catcgtcctc gatttctgcg gtttcgccaa tgacgattcc
     4141 cattccatgg tcgatgaaca cgccagttcc aatcgttgct cctggatgga tctcaacacc
     4201 agttaggaaa cgccagaatt gagcattgat cttcgccaat aaaaagagcc ggtgctgata
     4261 taaaaaatga gagaaacgat gccaaaacaa ggcatgaaaa ccagggtatg tcaaaacgat
     4321 ctcagctgtc gaacgtgcag ccggatcgtt tctctttgct gcatcaatcg ctcgggtaaa
     4381 ccaactcatg actttccact cctttcgtaa gaattttatg taggaaatca tcttcttata
     4441 aagaaaagaa gcgcctttta aataagtttc cttatcaaaa gacgctttcc gcgtggttcc
     4501 acttttcttc ataatcaatg attatctctg acagctaacg cctgttatac gttcttggct
     4561 actttgtttc ctataaaaca gtttttcctg ttttctgtgt ttcgccaaga ccactcccag
     4621 aggcatttcg gcaaccattc attgatacct tgcaccaccc ggtatctctc ttgtaatgat
     4681 cagctgctta cttttttctg ttcatcgtgt ttagttcagt acttgattta aatgtgctaa
     4741 tgatttttca cgaccaagca attcgatcgt ttcaggcaat tctggaccat gcatttgtcc
     4801 tgatacagct acacggattg gcatgaaaag attttttcct tttacgccag tttctttttg
     4861 aacagctttg atggcagctt tgacagttgg agcatctact acttccattt gttctagctg
     4921 tgctttgaat gcgtggagaa cagtaggaac tgtttcacca gcaagtactt cttttgctgc
     4981 ttcattcaat acaggatgtt cattgaaaaa tagcgtagac agatcaacga tttctgcagc
     5041 atagctcatt tgaggttgat acaggctaac gatcttcttc acccattcga ttgtcttttc
     5101 atctgggttt tctgctacac gtccatcagc gattagataa ggcagacaca tgtcagtaaa
     5161 tgcatctaga tccattgctt tgatgtaatg gttgtttacc cattgcagtt ttttcgcatc
     5221 gaaagctgcg ggtgatttac ttaggcgttt tggatcgaac attttgatca attcttggtg
     5281 ttcgaagatt tcgtcttcgc ccacaggtga ccagcccaat aatgcaataa agttgaacat
     5341 tgcatctggt agatagccta attcgcgata ttgttcgata aattgcaaga ttgattcgtc
     5401 acgtttgctt agttttttac ctgtttcact gttgatgatc aatgtcatat gtccgaaggt
     5461 tggtggtgtc cagccaaatg cttcatagat catcagttgt tttggtgtat tggcaatatg
     5521 gtcatctcca cgtaaaacgt gagtgatttt catcaaatga tcatcgaccg caacagcaaa
     5581 attataagtt ggcataccat cgcgtttttg gatgacaaag tcgccaccga tattatcgga
     5641 ttcgaacgaa atagcgcctt tcaccatatc tgtaaatgcg tattctgtat tgcgaggcac
     5701 acggaaacgt acaacagatt ctagaccttg tgcttctttt tctgcttgtt cttcaggtgt
     5761 caagttcgca catgttcctg cgtaatgagg catttctcct cttgcgcgtt gtgcttcccg
     5821 ttctgcttct aattcttctt ctgtgcaata gcatttgtat gctcgattgc tagcaagcag
     5881 ctgatcaatc agcggttgat agatttcttt acgttcagat tgacggtaag ggccgtattc
     5941 tccaggattt tcaggagatt catcccaatt cattcccaac caagcaaggt tttccaactg
     6001 gcttttttcg ccatcttcga tattacgttt ttggtcagta tcctcaatac gaataataaa
     6061 gtctccatca ttgtggcggg caaacaaata attgaataat gcagttcttg catttccaat
     6121 atgcaggtgc ccagttggac ttggtgcata gcgtacgcgt actttcgtca ttttcttcct
     6181 cttctttcaa actagacttt gactaacagc aaaaattccg tcagttacgg cttctcaaat
     6241 atcatttatt taaagccact cagcacaaat tttacctttt ctaaggtaaa tagtaaagcc
     6301 aactggttga atttccttac cagttggctg aatttctttt ttattttgat tgtttagtct
     6361 ttttctctgt ctctttttta ttgtcgattc ctcgtcctgc atgtgcaggt ttagcaaaga
     6421 tcatgcgtcc agcagctgtt tgaagggcac ttgttacaac gacttcgata cgttcattca
     6481 tgtaatgctg tccatcttct acgacaacca tcgtgccgtc atcaaggtag gctactcctt
     6541 gttggcgttc tgtcccggct tttactacta gaacattcat cgtttcacca gggatgacga
     6601 ctggttttac ggcatttgcc aacgcattga tattaagaac aggtacattt tggaattcag
     6661 agactttatt caagttatag tcattggtta caatgacacc atctaaaagc ttagccaatt
     6721 tgatcaattt gctgtctact tcactgatat cttcaaagtc tccatcgtac atttcgacag
     6781 atataccctc ttctttttgc aaggcattta ggatatctaa tccgcgacga ccacgcacac
     6841 gtttcaaact atcccctgag tccgcgatgt attgtagttc gtaaagaaca aaattaggga
     6901 tcatcaaggt tccttctaag aatccagtct ttgtaatatc ataaatccga ccgtcaatga
     6961 tcacgcttgt atccaagatt ttatatttat ggaaattttc tcctgatttt cgttctaaca
     7021 gttgactctc aacttgacta gctgtttctt gctcgatttt tttgcttcgt gaaccaaaaa
     7081 ctttcttcca ttcttcgatt cgtgtcgttc ccattctcaa tcccagatag cctaagatga
     7141 tcatcagtaa aatcggcaat acactattga cgaatggaat ttccatattg taaagagggg
     7201 tcgagatcac aacacctaaa gtcaatccga tgatcgcacc gatcgcaccg aagagaagat
     7261 aagtcaagct gacctcactt agtttttgtt ctacttgttt gataatagct gagatatgtt
     7321 tggccaacag caaagataat aaaaagaaaa taagtgcgcc taacaggctg ttggtaaatg
     7381 tattattcag ccatccgttt gactgttgac cgattgcctg ccaagctgag ggtaaaaatg
     7441 aaatacccaa gcttgcgccg acaatgatca tcagcaaagt aatgacacgt ttttgcatcg
     7501 tttttcctcc gtttcgacaa tcatttatta gttagcggaa cacacgcttc aacgtttcag
     7561 ccaaagttgc tactccaact atctcgattc cttttggcgc ttcccagtta cctaagttgt
     7621 ttttaggtag gtatactttt gtgaagccga gtttttggac ttctttgact cgttgttcaa
     7681 tatgactgac acgtctgatt tctccagtca gtccaatttc accgatgaaa cattccgttg
     7741 gctgtgttcc tttttcttta tagcttgaag caatactgac agcgatagct aaatcaatcg
     7801 ctggttcatt taattttacc ccacctgcag cttttaagta agcatcttga ttctgaagaa
     7861 gcaacccagc tcttttttcc agcactgcca tgatcagaga tacccgattg aaatcaagac
     7921 ctgttgttgt tcgtttggca tttccgaaca tagtaggtgt gactaatgct tggatctcta
     7981 ccaaaattgg acgtgtccct tccattgcca caacgatagc agagccagtt gcaccgtcta
     8041 ggcgttcttc taagaaaatc tgtgaaggat tagcgacttc ttccaatcca tgctcatgca
     8101 tttcaaaaat cccaatctca ttcgttgagc caaatcggtt ttttactgct cgcaaaatcc
     8161 gaaaactatg atgttgttca ccttcaaaat ataacaccgt atccaccata tgttctaaca
     8221 ttcttgggcc ggcgatcgag ccttctttgg taacatgacc gacgataaaa atggctatcc
     8281 catttgtttt agcggttttg agtagttctg cagtggtttc tcttacttgg ctgacacttc
     8341 ctgccacact tgtgatgtct ggctgcgtca tcgtttggat ggaatcaatg ataacataat
     8401 caggggagat atgttcgatg gcacgactga tttcgttcat atctgtttca gcgtatagat
     8461 aaaattctgt gttgatactt ccgaggcgtt ccgcgcgtaa ttttatctgc tctgcgcttt
     8521 cttcgccgga tacatataag acttttccgc ctatggctgc taattgctga gaaacttgta
     8581 acagcaaagt ggatttcccg atacctggat cgccaccaat caagaccata gaccctggca
     8641 ccacacctcc gcctaacaca cggttcagtt cttctaattt tgttttgatc cgaggttctt
     8701 ttttagggac gacgtctgcg atttttgttg gttttgcttt ttctcctgtc aaacttgtcc
     8761 gagttctgcg gtccgttgta tcttgttcga tttcttcgac catcgtattc cattttccgc
     8821 aatttgggca gcgtcccaag aacttaggcg acacataccc gcaattttgg caaacaaatt
     8881 gtacttttga tttttttgcc attgtaccgc ctccttttat cctaatcatg agacattaaa
     8941 tcaagcttaa gtatctttaa cgttttattt actggaagaa ccaaatccgc cttgacgttg
     9001 agcagtcgtt tgatcttgat ctgcttttaa aaacggcaaa aagatccctt ggccgatacg
     9061 ctcgcctttt ttgatcacta catccttgaa accaaagttg gtgaattgga acatgatatg
     9121 gccttcattt gcctcattat tgtaataatc actgtcaatc acacctactc cgtttgtcaa
     9181 cactaaaaac cgcttcaacg gattgcttga acggttagca agctgcaaaa attcatcttc
     9241 tcccatgtaa gctttgattc cagtaggcac gagggttggt ttcaattgtt tttcattttc
     9301 tgatacatct tttttcaatc catctgcgac tgtttccaac ccctttttcc agcctgcttt
     9361 ccagatactt ggaatcacga cctcttctgc tgcttcaaaa tcatagccag cagcatgatg
     9421 tgtagcgcgc tgcggtagat tgatattttg atctttatat ttagaaataa cttcaaatcc
     9481 tctttttctc accggttttc ctccctaaat aaactactcc tattctaaca tatccgaggc
     9541 tgtaaaagac tttctttaca aattcttcaa gaaattctgc tatcttaaag taaaccatta
     9601 attcgttctt tttccaaacg actgcaagtt gtacaaaaaa actatttttt acatgacttt
     9661 actcgtcaaa acaagtagaa tagaacgaaa ttaatgagtg gatatttgat tgaggtgtca
     9721 catgcgtaaa gaaattaaaa atgcaaaacg aattattgtc aaagtaggaa caagtacatt
     9781 gatttatccc aatggaaata tcaatcttgc ggcaatcgat cagttagctt ttgtcctttc
     9841 tgatcttaga aatcggggaa aggaagtgat cttagtctca tcaggagctg taggcgttgg
     9901 tatgcataaa ttacatttgt cagaacgtcc gactttgatt cctgaacagc aagctgcggc
     9961 ggctgttggt caagccgaac tgatgaatat ctataatcaa agattcagtg tatataatca
    10021 acagacggca cagatcctcg tgacaagaga cgtggtagat tatcctgaaa gtcgtaaaaa
    10081 tgtgaggaat acattggaac agcttttgat tatggacacg atccctatcg tgaacgaaaa
    10141 cgatactgta gcagtggatg aattagatca tctgacaaaa tttggcgata atgatcagct
    10201 gtcagccatc atggcaaaac ttgtcgcggc agaccttttg atcgtccttt ctgatatcga
    10261 cgggttttat tcagataatc cgactacaaa tcccgaggct cagatgtatc gctatatcga
    10321 taaaatcgat gaaaagattc tggcacaagc aggtggtgct ggtagcacat ttggaacagg
    10381 cggtatgcag agtaaattaa aagccgcttc taggatattt gaagcaaaca gcgcaatgat
    10441 tttagcaaat ggaaaaaatc cggcaattat ttttgatatt cttgcaggaa aagaagtagg
    10501 tactttattt aaggaggact tgaaatgact gacttgatgc aattaggaca acaggcaaaa
    10561 gatagcgcgc aacaactagc acttatgcct acaaaccgca aaaatgagct acttgttcaa
    10621 atggcacaaa ccatcaaaaa gaatcaacaa gcgatcattg aagcaaatca taaagactta
    10681 gaaaaagcag tcgaaaacaa tatcagtgaa acgatgcaag accgcttgca gctgacacct
    10741 gagcgaatca atgccatggc tacagagatc gaaaaaattg cttcgttaga cgatcctatt
    10801 ggaaaagtag atgagatgtg gacgaacacc gacggattga gaatcggcaa aaagcgcgtg
    10861 ccactaggcg tgatcggcat catttacgaa tctcgtccaa atgtcacgac agatgcagct
    10921 agtctagcat tcaaatcagg gaatgccgtt atccttcgcg gtggcaaaga agcattcttc
    10981 tcgaatcaat tattagtcca attattgcag caagtactgg tcagtgctgg cgaatctcct
    11041 tatgccatcc agtttgtcga tgatacttct catgaaactg caggacagtt gatgcgattg
    11101 acagaatact tagatgtgct gattcctcga ggcggagcaa aattaatcca acgagtcaaa
    11161 gaacaggcaa cggtacctat cattgaaaca ggtacaggaa ataatcacgt atatatcgat
    11221 aaagaagcac agttatctat ggcagtgaac atcatcgtca atgcaaaagc ttcccgtcca
    11281 tctgtctgta acgcggcaga aacattgctg atccattctg agatcgcacc ttttttcttg
    11341 ccagctattg aaaaagaact ggtagaacac ggggtctctt tacgtgcgga tgctcgtgcg
    11401 ttagaatatc tagagacggc tgctttagca gaagacacag attgggatac tgaatatcta
    11461 gattatatcc ttgctgtcaa agtggtcgat tctttggatg aagcaattgc acatatcaat
    11521 cggcataata ctaaacattc agaaacgatc gtgacagata gttatgcggc tagtcaacgt
    11581 ttcttaaatg aagtggacgc ggcggctgtc tatgtcaatg cctccactcg ttttacagac
    11641 ggatcggtat ttggttttgg tgcagagatt ggtatctcta ctcaaaagtt gcatgcccgt
    11701 ggtccaatgg ggttaaatga attaacttcc acaaaatata tcatttatgg cgatggacaa
    11761 atccgcgaat aatgtttcgt gtgaaacatt attcccgcct tttgcctttt ttctgtaaag
    11821 gttctatcca actagaaagg tgtcaatatg tttgaaattt taatgatttt ttttatttac
    11881 cttatttctc tgaatatcgc tgcttttctg ggagtcggta ttttatccct tttctttcaa
    11941 ttcaaaaaac gaagcatagg gagtcaacgg gaaaaatggt cgcagtattt tgacaaaatc
    12001 gggcaaaaag ggctggttac acgcttgcac attagttaca tggttgcatt atgcttatta
    12061 gcgacaatca attactattc ttttttcgat cattcaatcg cttatacgat tacgctactg
    12121 attgctggga tttttcactt atcttataaa tatcagctga ataaaaacca cttgaatcgg
    12181 actttccgct aaaaaatatc cgtacgataa gtagagtgcc ttgaagatcg gcaaaaaact
    12241 gccggacttt ttagaggctg tgacaaagat tttgtcacag cctctttttc catataaacg
    12301 gcgttcgcct accagctgcc tggtaaatct gtttcctctt cgttaagaag cgaaaatccg
    12361 tcaaatgttt cgccatcata ataacgaagc agctcatcca tggacaagtt catcgttttt
    12421 tctttttctt cttccgctga ttcagccagt agctgttccc gatacacctg atacatacca
    12481 gctatttttt gctgcatcgc ttttctagtt tcaccttccg cattgattat tggcaattct
    12541 ttgatatagc cacgataaat caaccgatca tctgaaaatt caatgggtaa ttcaacgagt
    12601 gtcaacccga cttcctgaaa atattcttcc agcatctatt atccccccat tctttttctt
    12661 aaatgaattt tagcttacct actgaaaatt ttccagtttc attattttga gaaaaaaagg
    12721 gaatgtgaca aaaatcgtgt cacatcccct ttttccgaat aaatggtgtt cttctgccaa
    12781 ctcctcaatc ataagtcaca atattcaaca aacatgagaa actgtttttt gaaattgttc
    12841 cttgtgattc agagttaaac gacagtctca caacctcttg gtaaacggcg ttcaatcagc
    12901 tgaccctcgg tattagctca aaaaacggta aaatatgaga agctattttt ccgttttgtt
    12961 tctctaatac ttaggataaa acgctgattt tacaacctct gttaaacggt gttcaatcag
    13021 ctgtccttcg gtattagctc aaaaaacggc aaaatatgag gaactatttt tccgtttgtt
    13081 tctctaatac tcaggacaaa acgctgattt tacaacctcc tgataaacgg tgttcaaaag
    13141 cttgcatctg cggtaataag cccaaccaaa cgaaaaatat gagaagctat ttttgtttgg
    13201 ctgttcttat gacttgatgc aggacagctt tttcacaacc tctgatttct tattcttctt
    13261 catttgtagc aaaataatta cggtgataaa tgatacaaca tacactgata agaacaatgg
    13321 cacctgcaaa ataaaacgca tagctttcac caatatgttc accaatcaca cctgcaataa
    13381 atggtgctaa agctccaccg aaaaagcgga caaaactata gctggacgaa gcaacgtttc
    13441 gttgcagacc tggtatttcc atagcaatcg tcgtcaacag tgtattgata attccttgga
    13501 aaaatcctgc taacacaatg ctgatcggta caaggactgg catagaagtt ccagctccta
    13561 ataacagcaa acaaataatg aataagacaa atgctgctaa aattgtccga taagtcgtaa
    13621 acttccgctc aagagccggt gcaacgaaaa tcgaagcaat agccagaagc acaccccagc
    13681 caaaaaatac aaaaccgact tctaattcag aatagccaat caataaaaat ggcgcatacg
    13741 caagtaaagt aaagaatccg aaattatata acaatgcgat tagtccaact gaacgaagtt
    13801 tatgattgct taacgctttg acaccttccc aaaggcctac ttttctcttt ggtttctcag
    13861 tttcaggtaa aagtaccgct agggctataa aaccgcaaaa catcaaaaat gctaccccaa
    13921 aaaatggata acgccatgaa ccactgccca agaccccacc gactagaggg ccaacagcca
    13981 ttccgcagcc aagtgctgct tcatacatca tgattgcttt ttctgtgtta ccaactaaaa
    14041 tactgacgat cgttgctaaa gcagtagaga caaataaagc attcccgaca ccccagccgg
    14101 cacgtaaccc aatcagcatt ccgatattcc cagataatcc gccaagacca gcgaatacaa
    14161 cgatgataaa caatcctgtc atcaatgttt ttttcaaacc gatccgacta gataagaaac
    14221 ctgtaaatag catcaccaca ccagtgacta acatgtaact agtaaataac agggtcgttt
    14281 cagctggcgt agcgtttaac tgtgcagcaa tcgtttttaa gattgggtct actagaccca
    14341 ctcccataaa agcgatcata caggtagctg ctacaactag cgctgaactt ttcccctttg
    14401 tttcttcatt tgtttgttct tgtatatcta tttgattctc caatatttcc atccctttct
    14461 ctctattagc atcatacatg atttatttta catgtcaata tgcacatgta aaacgtggaa
    14521 actttactgt gatataataa agaaaataag acgagaggta ggatttttat gaatacttta
    14581 gcctatatat tattatgcgt gcttttatcc aaaccacgtt ctgggtatga attgaagcag
    14641 ctgatcacaa ttttttggga agcccatcac agtcagatct atacaacgct tgccaagtta
    14701 gaccagcagg gttatgtgac cgttttggac aaagacgagc actctcaaaa aaagatctac
    14761 cacttgactg atgaaggacg tgctcttgta gaggaatgga tcaaagagga aactcccgct
    14821 cctacgcaaa aagatgaatt tctagcaaaa atctatgctt tttcgacgct cgataaaaca
    14881 acagctactg gactgctatt cactagagaa caacagctga acaaaatcat gcaaaaaaat
    14941 caaaaaaaat tgaatgacct ctcgctagac aagaaacaag aatttggacg ttatgttgtg
    15001 atccagcgca gaattatgct ttgtcagcag gaactccaat ggtgtcagca agtaagagaa
    15061 caaatgcagc agttttttga gtaagggata aacagaacct ttctagaaat atctattgaa
    15121 gagcaaatta tcttcaataa aagagcaata cagttggaaa agaaaaagcg atccgaacga
    15181 caggccaaaa cctatcgttc ggatcactat ttttctagaa ctgcattcaa gagactatga
    15241 caaaaagcat gccaaggcct tttttcaaat aacagtgttc catcattcat tactttgaat
    15301 tgcttttagc acacttcttg aaagcgggcc aacgatgatc aactgcaacg gtaaagcggc
    15361 aatcacattc attttccaag cattcatata agcagagaat aattgatcag gtattccttg
    15421 ttccatgatc acaccgaata aagacataca tgtcaccatt cctaaaacca tcaagcatga
    15481 aatagttaag atcatttgga ccttgctttc tggatttact ggtagtttaa aggcaatttt
    15541 tttcgccagc acaccgatga tgaagacatc caaaatgaaa gccaccacga atccaggcac
    15601 tagaccaatc aacaaacttg ataaatgaag atcttgatgc agccataaat tatacgcgct
    15661 catccccaag accatcaaaa aacacatcat tgttgtaaaa attattcctt cttttttatt
    15721 tgtaggcaat ctgtaccact cctttaaatt tgtcacgaaa atcatcgtag cacatttaaa
    15781 aatttctcgt aagtactttt tttattttct gcccttttat ttcataaact tcatcagccg
    15841 tacgctcgac aaagtaagaa tcatgagaag taaacaaaat cgttcccgga tatatttgca
    15901 ttagcttctc taaagcttcg atcgttgcca tatcaataaa attagtcggt tcatctaaca
    15961 gcaacacatt acttggctta gtaaaaagca aagcaatcgt cagacgggtc gcttctcccc
    16021 cacttaatgt acataacggt ttcgtcaaag tttcctgagc aaaccctaag tgattcagca
    16081 aactacggac aagcgattct gaaaactctg tttgtctcat gacaaaacga atgatggatt
    16141 cttcagatgt catttgataa cccttttgct gatatacttg aaagcttact ttcggagaga
    16201 gaaggattcc ttctccttgt ttgcggatat gttctaataa ggttgtctta cctgaaccat
    16261 tttcaccgac aatcgcgatt tttttaccta aagaaaactg aaaatcacca tttaccagta
    16321 atgttctccc acttctttcc aattggacat tttgtcccat gatgggatag cggctgtgga
    16381 gttcaagaga ttttggtact ggaaaacgga tttgtttcat ctgctgcggc ttggttgttt
    16441 ctcctatttt ttggagtctt ctctctaatg ttttcgcatt cttttggatg gctttttgta
    16501 cactgtcttt ttgtttagag gaagacaacc gatccagtct gatttgttgc tttttctttt
    16561 tactggacac tttttccaac ttttccgctt gttttttctt ttcttggatc gatttttcca
    16621 atcgtttttt ctctttcatg atcgactctg cttctcgtag ctgagtcttt ttctccaatt
    16681 ccttttgagt gagataggca ctataattcc ccgaaaactc tcggatttct ccgtctttta
    16741 cttcccagat tttcgatgct agctcatcta gaaaatagcg atcatgacta acaaaaacca
    16801 gcgtaccata ataataacga agctcttcaa tcagtcgatc aatacttttt ctatctagat
    16861 gggttgttgg ctcgtctaga agcatccctt gttcataaga agaaagaaga cgtatcaact
    16921 cgatctttcg ttcttcccct ccgctccatt tccgctctga agtttcttcc agtcttaact
    16981 ggaaatgact ggctaattcc aaatttaggt cctttgcttc agcgagatag gttaattgag
    17041 gcaggtagtt gaaggtgatc tctgtttgga ttttcccatg atcgggaaaa agttcaccgg
    17101 ctattagttt gagcaaagtc gatttaccga caccattttc tcctatgatc cctatacgat
    17161 cttgctgata gacacgaaga gaatcaatag atagttctag ctggttgcca aagctgactt
    17221 gtagatttgt tatatttact gctaaatttt ccatatgttt tacactccta tttcatgtaa
    17281 aacaacaatt atcgatacta aaaaagagca gaaaaatctg tttgcaaaaa aactgcatca
    17341 catcttttcc tactctgaac gaaataacta tgactaaatc accaaatctg tcatagcttt
    17401 cacctattct actgtcgttc gaaaaaatgg acatactcca tccatgaaat tgttgtttat
    17461 acatgtcttt tgaatttatt tagttgttat tcaaaagttc gaaacgtaat ttcatcgatg
    17521 cagtcatttt tccgacctcc ttttttatta ggttaccaca cacgattcaa aaaaagcaat
    17581 agctactgaa tagtaactga aaacctttta ttcgaacata gtgatctttt ctggtgctaa
    17641 acgaacagac tcgtaacctt cttctaccgc ttttcctatt gataaaataa taactggaac
    17701 ataacggtct ttatccaaac caaatgcctc tgccaactga tctgcttcga atccaccaat
    17761 tggatttgtt tcatagccat gatcacgcgc aactaacatg aattgcatag ccgctaagct
    17821 agaatcgact ttgactacat cgttcatttc ttctcttgaa aaactcttgt aataaggaat
    17881 gatcgcagct aattgttgat ctctgacttc ttttggcatc ttccctgatt cgtaagcttg
    17941 gttgtagatt tcttcgccat attcgtaaca ttgcatatcg ccaaaaatca tgaccattgc
    18001 agaagaagta tcattttgtc tcgtattgaa acggatcaaa ggacgcaaga tttcttttgc
    18061 ttcctcgctt tcagcgacca caaagcgcca tggtttcata ttgacagaag aaggtgcagt
    18121 cgtcgcttct ttgatcattt ccagcatttc ttcgtgtggg attttgtatg tttcatcata
    18181 tacgcgaacg gatcttctac cagtcataat tgttgaaaaa tcattttttt gttccattat
    18241 tattaacctc tttcgtttct gttgttatat tgcaaagttg ggtattcaat ttatctaaaa
    18301 gtgttagaaa ttgtttcatt tctacatcgc tgaaagccgg ggatagcacg gaacctgtat
    18361 ctttatggtc catttcacaa tgcttgattt tcttctgggc tttttctgtt agcgctacat
    18421 acacttcccg gttgttctga ggatttctct gacgcgaaac atagccattt gcttccaata
    18481 ccttcagatg acgagtaact gctccttgat caatctgcaa cttttcttgc aaactgcttt
    18541 gtagcaatgg attttcttct ttcagtctca tcatgatctc gtatctagta agacttatac
    18601 cgatattttc ttcaaagatc tggacgattt tttgatcggc taatttgatt tgatataaaa
    18661 ggtgactaat ctcttctaaa gacataattt cctcctttct aataattgac tcgtcaacga
    18721 ttgacttgtc aataatagaa taaaaaaaga aaaaagtcaa agaatcagct gtgtaataaa
    18781 aaaaacgctc tcaatagaaa agtatagaga aaagaaattt tttgtagaat gaacggaaaa
    18841 aatgataaag aaagcacaac gctaaaacca agattattga ttcttatcaa actatagaag
    18901 atagctcttc tgcagtagat aattttacac cgccaaaaat ttccgaaatc gccttttgca
    18961 agaatcccgt cgaatattag aaattggatc agtatgctta aacagtaata aaaaagttat
    19021 gacaagatgt tgtcacaacc ttttttgagt aaacggtgtt caaaaacttg catctgcggt
    19081 aataagttca accaaacaaa aaacatgaaa atctgttttt gtttggctgt tcttactact
    19141 tgatgcaggg cagctttttc actacctctt tttaataacc ataaaatcct attccttcat
    19201 atctccagcc catcggtgtt agccaatctc tttccttagc actcaaggta tagtgatggg
    19261 taccagtttt ttcatttgga ttaaatagtc gataaattgg cttggaacca ccagaataaa
    19321 aacttagacc ttcataacgc caaccgattt ttgttaaaga gttgatctca gattgtgcca
    19381 ttgtgtaatg atggtctcca ctgtaaggat tgtataaacg gtagacaggt tgtccgctgt
    19441 ttggtgcttg ccaagcaatc ccttcatatt cccagcctac agttggcaga taattttttt
    19501 ctccggcatt caatgtatat aaatgttctc ctgtatgacg gttatacaga cgatacatcg
    19561 gagaagttga agttggtgct gtatcatact gtgtcagatt ataggtttcg attacattgt
    19621 tcaatgtaga accataatta ggcgcagtgg cataacgacc tgttagccaa gccgtagcat
    19681 ctttgtaaga gttcgtattg cttttccatg caccggaata gtagtaaacg cctggctgaa
    19741 aagaagtcgt cttcaatacc gttacgttat cttgcaatga ttctttgtac gaaggatatt
    19801 ttctaaaagc ggcattcacc gtaatccatt gcccattcac atattccgaa gtaggcatcg
    19861 taacagattg gccattatag cttcctttaa tcccaaatag attgtaatta ggggcagaag
    19921 ccaaagtact gttcccccag ccactttcaa cgatggcttg agcaatcatg actgatgcat
    19981 ataagtcatt ggcacttgcc aaactttgtg cagttgaggc aatactatca atgaacgctt
    20041 gttgagaatt agcagatgag cgagcataaa aagcatagcc agtatagttt tcgaattcag
    20101 acaaatctgc ttgatgggta tgtgtcaatg tttgcccatc tgtcaattgg ttcgtgattt
    20161 cttctgcatt ctctggattg ttctgagctt ctgctgatgt actgtcttcg gtttgtgttt
    20221 gttctgttgt ttcagttgtt ggttcttcgg ttgaaattgt attttctgag acagtagctg
    20281 actgcaaagt actttctgta tcgttttcaa ttcctgtttc tgaagaactc gatgtctgag
    20341 ttgcgacagt ttctgtcgat tcttcagcta gcactgttgt gttggcaact gctagatttc
    20401 ctaaaagaat aacgctaaat aataaattct ttgctttcat cttttttctc ctttgaatta
    20461 tgaaactttt cctaaataac agtgtaacta aaaaagtaaa agcaagtcaa tgtccatatt
    20521 taaataacat ttgtttcttt ttaataaatt tgctttttct gcataaaaag acgtaaatga
    20581 agaatattct tctccattca cgccttaaat tgatggtcgt ttgaataact atttaacaag
    20641 taattctctc tggatattat ccgttatgga ttatacttcc tgtgtcgtcg gacggataat
    20701 catgttgctg acagacatcc ggtctggcgt ttctatcgca aatgctacag cagaagctat
    20761 atcttcagat gttaatcccc attctttttg cgcttcatga agttcaagag cagccttttt
    20821 gtcgctgatg gtttgatata attcagtttg aacagctcct ggagagatga tcgtagattt
    20881 gatgttattt tgccgttgct cttgacgtaa tccttccatg attgcacgga cagcaaattt
    20941 tgttccgcaa taaacggcgg aatcaggata aacaacatgt cccgccacag aatcagttga
    21001 aatgatatgc ccagattttt gtttttccat gattggaagt acggcggaaa ttccatttaa
    21061 cacacccatg atgttgatat caagcatatt ttgccattca tcacggtgac cttcaactaa
    21121 tggagcggtt ggcatgattc ctgcattatt gtacaataca tcgattcgac cgaacttttc
    21181 catcgctaaa tcgataactg cttggacttg tgcaaaatct cttacatctg ctgtttgaat
    21241 atatagctca gcttctggta aagattcttt tattgctttt aggcgatctt ctcggcgtgc
    21301 agctataact agtttagccc ctttttctgc taatagcttc gttgttgctt caccgattcc
    21361 gcttgaagcg cccatgatga caatcacttt ttctgataaa tcattcattc tattctcctc
    21421 ctgttttgaa aaatctcttg cttatactca ctatctctta tttcatctta ctgttcaaat
    21481 aatccgttcg acaggtttga cgattttggc agggattcct gcaacgatgg tattgtctgg
    21541 gacatctttc gtaacagttg cattcgctgc aacaatggca ttctcgccaa tcgttacgcc
    21601 tggcagaata gttgctcctg ctccgatcca agcatttttc ttgatgtgga ttggctttac
    21661 tgacaagcct cttcgttctt ttggatcggt tagatggttc accgtgatga ggttgacacg
    21721 aggaccaatc aatactgaat cttctaaaca gatgccacct aagtcaacga acatcacttg
    21781 acgattgata aagacatttt tccctatact aatatgtttg ccgaaatctg tataaaaagg
    21841 cagcagaaca gtcaccgtat catctacttt gtcactaatg atattttcta gccgtttgcg
    21901 gatatctgct ggttcatggt acccagtatt cagcgctgct aaaggctctt cgttttccgc
    21961 ttggatctga tggatcactt caaagagcgg atccgttact cgaatctctt tattgacgat
    22021 ttgtttttcg atgaggcttg tcattttgct ccctcctttt atccttactt tataacggac
    22081 ggcttatgat gtctaatact tataaaacat acttaactat tccttttaac tatacttagt
    22141 ggtatgcttt tttaaaaaca ggagggaaaa aatggatatt cgtatactga cgtatttttt
    22201 agcagtagct agagaaaaaa atatcagccg agcagcaaaa tctctgcata tcacgcaacc
    22261 tactctctca aaacaactga aagatttaga agaagaactt ggtgtgacac ttttcactcg
    22321 aggctcccga gagatacagt tgacggattc tggtcgatat ctttattcaa aaggaaaaga
    22381 aatcttgtcg ttggtagaaa aaacggcgaa caatttaaca aatgacgcaa tcatctctgg
    22441 agaaatctac attggcggag gcgaaactaa agcaatctct ttcatttctg atagccttca
    22501 ttcgttgatc aaggcgcatc ctgatatcca gtttcattta tatagcggga atgcagatga
    22561 tatcatagac aaactggata gcggattact tgattttgga ctcgtaatcg aaccgacaaa
    22621 caaacaaaaa taccagtcat ttcgactgcc agcccaagat cgttggggac ttttgataca
    22681 tcggaatcat cctttagcaa agcaaacagt catccatccg caggaactga aaactgttcc
    22741 tttgatcatt tcccggcaaa cgtcagtgga cagtcaacta gctgaatggc taggtttcag
    22801 catagatcag ttatcgatcg tcggaacata taacttattg tacaatgctt ctttgatggt
    22861 cgataacggg acttttggtg cattagctct agatgggatc atcaatactt atgggacgga
    22921 aaaagtattc atcccactcg atccgccatt acaagcttca ctgaatctca tttggaaaaa
    22981 agaccagcct ctttctcctg ctgctcgtaa atttttagat gtcctaacgg agaaatacag
    23041 ttaagtagag tttttttcct tcgctttcag ctttttaaca acgaataagt taagcaaaag
    23101 atccaatgat taaataacat aagtttctta atttgttcct tccttttatt tctgataatt
    23161 ccagtaaatt actataatta taaaaaaaga attgacaaaa cataactgtc tatataaaat
    23221 tgattacgtt aacaataatt cgtttcatgt gactagatca tactaggcat gaaaaatctc
    23281 tgaggaacat ggtttcccta ggaggttttt cgtgtctatt tttgtttggc cgcaatcaac
    23341 tggtctagca aacgtgaaaa ccaaatcttc aaaaagggtg cgcgcatgaa aatcaaaaag
    23401 atctttaatc aaaatgcagt attggtagat gacggtggac aggaaaaagt agctattgga
    23461 aaagggattg gatttgacag aaaaagaaat gatttgattt ttgatcgtga tgtcgaacgg
    23521 atatttgtca tggaaccaga aggtcaaatc aagttgcaaa atttacttaa tcagattgat
    23581 gaacgctttt tatttgcagc agaaacgatc attgatcatg cggaaactgt tttgatggaa
    23641 aagttgaatg aacatgtatt gatcgctttg accgaccaca ttgctttttc tgcggagaac
    23701 attaataacg gtatcgtcat ccgcaacaaa cttttaagag aaatcgaagt gctttacagt
    23761 gatgaattca gtattgctca atgggcagta gagtatctga caaaagagct tgggattcca
    23821 tatacttatg acgaagcagg atatatcgca atccatattc acagcggacg aagcggtcgg
    23881 aacaataacc atcgcagtat ccgtgaagtg acgattgtat ctgacatcat ccatttagtg
    23941 gaatcagaat tggaaacaga tatccattca gaaccatttt cactgaatta ttcaagactg
    24001 gtgaatcatt tacgactgct tctacaacga acccatgcgc aacaatatgc tgttttagac
    24061 acggaaatcg tagaaatggt caaacgaaaa tacccagaaa gctataagat ttctaaaaaa
    24121 atccgtgtgt tgctgaccaa agaataccag ctcgcgatca cgaaagaaga actgggttac
    24181 ttggccatcc atatcgagcg tttaagaagc gcaatcgtac aaacaaatgt taacaatcat
    24241 gaggaggaaa aaaattgaaa gcatatctac aacgaatggg acgttccctt caacttccag
    24301 ttgcggtctt acctgctgct gctttactag tagggatcgg aaactggtgg gcatcttata
    24361 gtaacgacat tgtcgctcat tttttacaag ctggcggtaa cgcagtttta ggtcaattac
    24421 ctttgctgtt tgccgttggg ttagcactag ggatgtcagt ggacaaatca ggtgctgctg
    24481 ccttggcagg tttggtcgca tttgaagttc cagtaaatgt tttaaaaact gattcagtag
    24541 ctactttatt gaatatcaaa ccagaatcag ttgatccatc ttttgctcag atcagtaacg
    24601 tatttattgg tattattgcc ggattgattg cggcagctct ttataatcgt ttccacgaag
    24661 caaaattacc gatggcttta tctttcttta gcggcaagcg tctagtgcca atcttggctg
    24721 cctttgtcat gttgctgatc agtgcagtgc tactgctcgt atggcctccg gtttactctg
    24781 ctttagtttc ttttgctaaa ttcattttga gtttaggctg gggtggtgca ggtctttatg
    24841 gcttcttcaa ccgtttactg atccctacag gattgcatca agcaatgaac tccgtgttct
    24901 ggtttgacgt agcaggaatc aatgatattg gtaaattttt ggcttctgaa ggaacaaaag
    24961 gcgtaacagg aatgtatcaa gctggatttt tcccaatcat gatgttcggg cttccagcag
    25021 gagcatatgc tatttacaga aatgcacgtc cagaaaacaa agcaaaaaca gcttccttga
    25081 tgttagcagc agcttttgct tcattcttta ctggtgtaac agaaccactt gaattctcat
    25141 ttatgttcgt tgcttggcca ttatatgtct tgcatgcaat tttcactggg atttctttag
    25201 cagtgagtgc attcttccat tggacagcag gatttgcctt tagtgccgga tttgtcgatt
    25261 acttcctatc tttgaaaaat ccgattgcga atcagccatt gatgttgatc gtccaaggat
    25321 tagtaacagc agtgatttac tactttggct ttaactttgc tatcaaaaaa ttccatctga
    25381 tgactcctgg ccgcgaggaa gcagatcttt cagatgacga tactgcaacg actaattcag
    25441 acaataaata tgcggcacaa gcaagcaaaa tctacgctgc attaggcgga gccgacaatg
    25501 taacttcgat cgataactgt actacacgcc ttcgtttgca agtcaaagat acaggcctga
    25561 tcgatcaaaa taaaatcaaa gccactggcg tacctggtat gaagatcatc gacggaaaaa
    25621 atgcgcaagt catcgtaggt acagaagtac aattcgttgc agatgagatg gcaaaactac
    25681 atggtggtgc tgcaacacga cctgcacaaa caaacaccgt ggttaaaaca gaaacatttg
    25741 ccggtggaac gatcgaacaa gatatttacg ctatcgcaaa tgggaaactg attccaatca
    25801 ctgaagtttc agatgatgta ttcgcggaaa aaatgatggg tgacggctat gctgtattac
    25861 cagaaaatgg agaaatcttc tctccaatcg ctggtacgat cacaaacatt ttcccaacga
    25921 aacatgctgt cggaatccaa acagatgctg gtatcgaagt cttgcttcat atgggcatca
    25981 acactgttga cttaaaaggc gaaccattca ctttatatgt aaaagaaggt caaaaagtcg
    26041 caagaggtca attgattgct ttagttgatc ttgccgctat tcaatctgca ggcaaaaaca
    26101 cggatatggt cgttgtattc acaaatggcg acaaagtcca aagcttagaa atcgaacccg
    26161 cacgtgatgt aaaagcaaat gataaaatcg gctctgtttc caacaaagcc tgagccatcg
    26221 tcttccccag acttttttat cgataaacaa acaggagctg agacaaaaat cttgtctcag
    26281 ctcctttttc cgaataaaaa cggcgttctc ctgccaactc cgcggtaata agtccagcca
    26341 aacgtaacat atgaagagct attttttatt tgactcttct tattacttga tgcagaacag
    26401 cttttttaca acctctgata aacggtgttc aaaaaccagt ttatcggtat gaagtcaaat
    26461 ttatgcaaaa atgtggaaag ccattttcac aaaatttttc ttcatactca aaactaatcg
    26521 gctttttcac aacctcttta tacattattc ctgatccaat atttctttta atgctgcttc
    26581 aagagaagtt aatggttttc ccaatacttt ttctaaatca tcagaggaaa tagctaactg
    26641 atccttttta atatcatgtt ggatcgctaa aaacatgtca gctgcttctt gagggaatcc
    26701 ggcttctttt agattttcga caaacgctgc atcacttgct tcaataattt ctaacttttt
    26761 acctgtcgca cgctctaatg ccttggctaa ttcttcatag tcagttagat tgccggataa
    26821 ttctaagatt tctggagagt cactttctac tagtactttt gctgcagctt ctgcatattc
    26881 acgtttcaat gcccaacctg tttttccatt tcctgcagca taaacgaatt gaccagtttt
    26941 taaagcctgc ccaatgatag gtaattcatt ctctacatac caattattcc gtaaaaatgt
    27001 atgggaaata cctgaatcct taatcatttt ttcagtgaat tggtgatctg gcgctaatac
    27061 actgatcgag tgatcggcat ctgcaaaact tgtataagcg atataagata ccccagctgc
    27121 ttgtgctgcc ttcactacat tcttatgttc ggcttgacga tttcctggaa cgccagagac
    27181 aaaaagcaat cgatctattc ctttcaacgc ttctttcatt gagtctaaat catcataatc
    27241 accaatacgt atattaaatc cagcttcttt cagtgcttct cctttttctt cactacgtac
    27301 tagtacatag atttcatttt gtggaaccat cttttttaag aattccagcg cataaccacc
    27361 aaaacctcca gttgctcctg ttactaaata atgcatattt gccactccct attcttttta
    27421 tttgttaaga tttacagctg tacatttata aattacacct ttatcataaa gagtgtggta
    27481 agataagtca agcaaaaaaa atgaaaggat gacaactgat gaagtattct ctgcaattta
    27541 gtgatgcaat ccatgtactt gcctatattg aaatgtttca agatacccga tcactttcta
    27601 gtgagatgat tgccagtagt atcgaaacaa atgcagcaaa tgtacgtaaa atcatgagtc
    27661 agctcaaaaa atccggtttg atctttacaa aaaccggaaa accgcagcct tcccttgcca
    27721 aaagtccaga tcagatttct ttactagatg tctatcgcag catcgaaggt aatacacagc
    27781 ttatccaagt cgatccaaaa acaaatccaa attgcgtcgt tggtgcgaat atccaagaag
    27841 ctttagaaga aagctacgct cggctgcaga aaaaggcaga agaagaaatg gctaagatca
    27901 cacttgatag tctgatacat aaaatagccg ttttggaaaa agaaaaaaga ccagaaaaca
    27961 caggcctcgt agagagattt ttataattct ctctactgtg cctgcatttt tctgatcgga
    28021 atcgtctaca taaattcttt tattctccgg gggacaaaag ccttgtcatg cccctttttc
    28081 ctctctaatg ctcaggtcaa agcgctgaag tcatgacgtc ttgataaacg gtgttcaagt
    28141 agctgaccct cggcattagt tctgaaaaat gcaaaatatg gaaagctatt tcccattttt
    28201 cctctctaat gctcaggtca aagcgctact ttcacgacct ctatattatc atggtttatt
    28261 gactaccggt atccagattt ctcccatata tttcccgttg gtaactccca tttcgactac
    28321 agcatttgga cccccaacat aggcgtaatc ttctacttct cttaaaacat gcccaaaggc
    28381 cgtattcgtc aaatcatttc ttaattcttc aggcgattct gctaaagcga ttacaacaag
    28441 atacgttcct tttgggaatg ggatgattcg ggtagtgttt ggaacatcct gactcgtttg
    28501 aacaccgaca tagtacatca ttttcccgtt atagggttcg ttgactgtaa agaaataatg
    28561 attttcagca gcttgtttca atgcatctat tgttccatta ccgataactt tttgctcaaa
    28621 tgcttgtttc tctgcagcca aaccgacaaa atccgtattg ctactcttca attccacacc
    28681 aatacccgtc accgtaaaat ctggtttttc ttcgatccta tactttgcca tttctcccac
    28741 cctttctatt atattaagtt catcttacat aaaattaaag ggaaatgaca cgattacgct
    28801 cttttttcta gggatatttt tattttttaa ctattttttt gctttcactg caatccaaat
    28861 ctcactgtaa acattactga aatcctctcc ccattttgta aaagagatct cgggagcttc
    28921 gactaactca taatctgaag aaggaagcca ttctgcatag attttccccc aagtatcttg
    28981 taaagtttgg ggaaatggcc ctttattagg aaaaatggcc caagtgtgtt cttctatagc
    29041 aagcatttct aaatcagcgt acggattttc ttttgtcgta gcaaagccaa tcatgtgcat
    29101 caaactgccc ttttcttcca agcgggctcc atcaaatcca taagaaacgt tgattacttg
    29161 atttggatat aaatctccta acttatgcat ctcttccctt tgagtctccg tgatcgtctg
    29221 cgctaacttt tgtatttctt gattgactcc ttcaaatttg acaggaactt ttttcgccac
    29281 acctgccaca taaaactgtt ctttcttttc gatacgaaat tccatcgatt ttcctcctct
    29341 gacatcaata aaaaatgtca agcgtggaaa agatttttgt atgccgtatc tgctgatttc
    29401 tgaaggcaga tatcctgacc aatcacgaaa agctcttgaa aaaccttcga ctgtttcata
    29461 tccatatcta aacgccgttt ctgtcactct tgatccatct aggagatcgc gattagccaa
    29521 agccaatcta cggtttttga tatagtccat tagcgacatc cctgcaataa acgtaaagat
    29581 gcgttttaat tgatattcag agattcctgt attttcggct attattttat aggaaagtcc
    29641 ttctgtcaaa tgttcttcga tgtaatcgat caattggttc agatctttaa gcatatttat
    29701 cttcctcctt gcttgccttt ttatcatatt atcaaagaaa gtcaattact tgatgaatca
    29761 ggaaccaatt tagtcagatg tagaaaatgt tgtatggatc taaagaaaat tctcaagcag
    29821 cgtttcgtaa cggataattg gtattatctg cctatctatg ttttaccttt agaaaaataa
    29881 attttgggga agacacattc taagtaaaca aagcggtaaa aatatctttt attcccttag
    29941 ttaatccgct tactacctac tgtacaaagc aaattgttgt tcaaactgct gatcagaacg
    30001 ctgcttggat ttttctttgc gatacatcat acctctttta tcaattggaa caattattta
    30061 tttctaacaa aatcacttca tttttgtcag ataaataaaa aacaaaaaaa gttccatctt
    30121 taaaacacgc tattctttta ctttttctca cattctctaa gaaaagaaaa ggagaatgaa
    30181 tttttgacaa ttcgagcaaa agtgattatc aaatatgtaa aatcagctac ttttttctta
    30241 aacgtttctt tatactaaat ataaataagt gtttcatgaa aggagaacta gatgaataat
    30301 tggcttgagt attttcctga aaacgttttg gaacgcggtt acagctatca tctgcacggt
    30361 tttgtccgtc atttgaacta tacaagcaag tacttgtccg caacagtttc tggcacggaa
    30421 gattataagg tagtgatcac ttgggatgaa aagaccaaca tgacttgtga ttgtctatat
    30481 gccatagaag gaaaaaaatg caaacacatg gctgctgtct tattcgctta cgaagaacgt
    30541 ccaataaaaa aatccaacta ctcactttcc gaactctcgt cccttgtttc ctccgctagt
    30601 tcctctcttg tacgggagct tttaacagag attcttatag aacatccgca atttatcgaa
    30661 cgcttcaaag ttaagatgcc atttcatgca ataaattatt cagataaatt aacaactatc
    30721 atccataaat acgatcatat tatcaagaaa aacaaaaaca ggaaaacagc gaagttcatc
    30781 atggagatgc gaaagttcat ccaagaagca gttgaatcgc tcattcagca aaatgcctat
    30841 cttcccgcat tcgaattgat caatgaagtg attgctactc tcgaaacatt ctattgggag
    30901 cctgaggatg aacgaaccct tcttctgata gaggactgtt attatttatg gaaagaatta
    30961 ttagcagaag cacctcatgc agaaaaaagg caaatgttct cttggttcgt ctgccaagtc
    31021 gatcatactg acgcctctta ttcaaaacgc tactccataa aaatcctgaa agaagacttt
    31081 cgggaaaaag aattttctaa ccaaaagaaa aaaatagata aaaaaactaa agaaacggta
    31141 aagaaagacg atttcaatga aaaatagcaa gtaaacgata acaaccatcc taaatccaca
    31201 agaaatacag cagaccttgc tttaaaaaca cgaatcatgc aaaggatgaa gtaaagaaga
    31261 cttaacgcgt acccaatatt agtcatttga ctattaggta cgcgttttgt tttataagtc
    31321 atgacaaatt tccttcgttg ctgggtagat tttccggcat tgttgataga ttttatgata
    31381 cttttctaca ttttgtaaga gaggttccac tgcatctgta tattggataa aattctgaca
    31441 acaactttca ggtgtgtcga accactctaa tctttaaaga taaatattaa aataacgatt
    31501 aataatatta acagtcttta tttttcacca ccaaaaacct atctttgcat atactaaata
    31561 gacgtatata cacagatagg tttgtcttgt gaaaaataat gattatcctt accaaaaaat
    31621 gtttgttttt ctacatgttc gtacttatca aaaaatatga tccttattga aattactggc
    31681 tatttatatt ccaacgactt cttgtgttaa tttttgttat ctcatagtaa attatgtttc
    31741 attttcactt aatttagttg tcacgtgttc gtcaattcgt aaaaacggta aatatataaa
    31801 cacacttgcg gctataatta atatttgtaa aacagctgct cgccagtctc cggctgttgc
    31861 taaaaatccc gatataactg gtggcgtagt ccaaggaatt tgcactacta catgattaat
    31921 taatcccaca gcagttgcaa aatatgctac tgtcaaagaa aaaatcggtg caagcacaaa
    31981 gggaataatc agactgatat taaatacaat aggcaatcca aaaataatag gttcgcttat
    32041 attgaatata gcgggagtta ccgataattt agcaaagtcc ttataatctt ttctacgact
    32101 gaagataaat attgcaatca ataaagcaat cgtatttccc gatccaccca ttaccgcaaa
    32161 ggtatcttta aaggccatat tgataatatg tggaatttgc tctttgtttg cataagctgc
    32221 catattttct tgcatattct gaatcaaaaa cggatctaac aatgaacctg atattactgc
    32281 ttgatggata ccaaatccaa aaaatagatt agcaatagat gtaattaaca aaaatcctgg
    32341 taaaccagtt gtaattttac ttaatggctc tgtaactatc gtggtaatta gcttatttat
    32401 atccatatta aacaattgaa tgattataaa tgacaataaa gcaaacgagg taatcgtaat
    32461 aatgattggg attaatacat taaaagactt taaaacagcg ggaggaatat ttccggatag
    32521 ctgaatctgt agtttcttat tattagaaag tttaataaat aattctgtag ccgctaatcc
    32581 aacaaatata cctacaaaca ttcctgaagc tcctgtatag gatataggta tcacacccgt
    32641 cacttcaaca gctttatccg cattttcagg agtaaacatc atctgcatag gtgttaatac
    32701 aacaaatgtc gaaatagcaa ctaataccgc tgcaatatga tttgtataat ttctgcttgc
    32761 acacatatga taagatactg ctgctacaac taataatgta gttatgctta atgtaccatt
    32821 ggcaattgaa gtaccaattt gttgtaacgt ggtcaatgta ctagtatcga caatttcccc
    32881 catgaatcct gttggttcta agatcactga attaataagt gtcacaaatc ctgctaacat
    32941 cataaatggc ataaatgtag caaacgcatc tcgcaaagtt cttaaatgga tctgattccc
    33001 caacttagtc gcaactatac caaatttttc aaatacaatg tccttcctgc tacttttgcc
    33061 catatttttt ctcctttatg cttattgtaa tcgattactt tttccaccca aataatacat
    33121 cacttatcaa aaaaagtaaa tacttttaat taaatatata tatctttttt agtataaaaa
    33181 aataagctct gaaaaaataa ttttcccgag cttatttttc aacaaaaaca gcttcaaaaa
    33241 caaagtcttg atataaatgt ctcgataccg aatactcgaa aggtttacca gacgatagag
    33301 caacaacttt gtctatctca atcataaatt cacctggatc tatttttaat atttttgcgt
    33361 caaattcatt cgcagtatct cctttgatac gtatgtgcga agtctttatt tccagaccca
    33421 gttcatttgt gatataagca tatacagatt tctttaaatg ttttggttcc aagcctggta
    33481 tgactgctaa tggcatgaat gtttgctcaa tcgagtatgg ttgacaatca ataaaacggc
    33541 ttcgtacaat attatataca tagtctttta cactgatact taatttatca gctacttttt
    33601 tcgatggaag ttcaattgag aaagtatgga tttctgaatc tacgtgttct tcaccaacca
    33661 cgctaaacaa accttcgttt ggaccaagaa ctcgtgagtt atcaattggt gttctgacga
    33721 cttcagtccc atacccactt ctacttcgca aaactccttc ggaaacaagt aagtctacgc
    33781 ctttctttac tgttaacttg cttgtatgat aaataactgc caattcatct cctgtaggaa
    33841 gtttctcacc aattttatac tctccattta caattttttt ctttatatct aagtaaattt
    33901 ccatatactt cgcaattttt ttcaatggtg accctccaat caaaaacata tcttcatcta
    33961 tactttaaca taaataaacc gataaaatcc acatcaaaat tatacacaca ataaaaaaga
    34021 tatatatatt taaacaaaac tatttacttt aagttgtaag cggtgttatc attaagtgga
    34081 aacaggaggt aaaaaaatta tgacaactat gaaaaagcta acttttccag atgatttttg
    34141 gtggggttcc gcttggtcag ctgagcaagc agaaggaaaa ggagaaacag gaaaagcaga
    34201 gactatctgg gatcgctggt ttaaagaaca accttaccgg ttttatcaac gaatcgattc
    34261 ctctattaca accgatcaca tccatcaata taaagaagat atagaactaa tgaaaaaaac
    34321 tgggcataac tcctttcgcg tttctatttc ttgggcacga atgtttccaa atggcggtac
    34381 cggaaaagta aatcccaaag ccatttcttt ctatcgaaaa ttattttccg aaatgaataa
    34441 taacggaatc aaagtatttg ccaacttata tcattttgac atgcctgcta ctcttcaaga
    34501 taaaggagga tgggaatcac gtgaagtagt tgatgcttat gttcattacg ctgaaacttg
    34561 ttttaaagaa tttggtgact tagtttgtca ttggtttacc ttcaatgaac cacttgggcc
    34621 tattttaggt acttatcttg aagattttca ttatccaaac ctcattgact ttaaacgcgg
    34681 agcgcaagca gcattcttca ctatacttgc acacgcaaaa gcaatacaag tatttaaaga
    34741 actagctctt cctagtaaaa taggcgttat tctaaatttg agtcctactt ttcctcgtag
    34801 tcaaaatcct gctgatgtga aagcagcaga aatcgctgat ttattttata cgcggagctt
    34861 tttagatcct atggttaaag ggaatttttc taaaaagctt atcctgttat tacaagaata
    34921 taatcagctt cctgaagatt atacgaaaga agatcttgta tgtatctacg aaaataccgc
    34981 tcaaattctt ggactaaact attacgagcc acgtcgcgtc aaatctcgtt cttctatggt
    35041 ggatacatct agtccatttt taccagagtg gtttttcgaa ccacatatca tgcctggacg
    35101 acgaatgaac gaataccggg gatgggaaat ttacgaaaaa ggaatttatg atttgtgcat
    35161 ggatatcaag aaccattatg gaaacatcga agcatttatc tcggagaacg gaatgggcgt
    35221 tgcggatgaa gaacgtttca tggatgatac agggcaaata attgatgatt atcggattga
    35281 gtatatcaaa gatcatcttg cttacttatg gaaggcaata aatgaaggat gtaacattaa
    35341 ggggtatcat ctttggacat ttattgattg ctggtcatgg atcaacgcct ataaaaaccg
    35401 atatgggctg gtttcactcg accttactac tcaaaaaaga acaattaaaa aaagtggcga
    35461 attttacaag caattaagtg atacaaatgg atttagatac gatgtagact tgttagttga
    35521 ataatattct aaaattccac ttgaagtgaa cacattagaa aacaagaata atgagaaata
    35581 ccaataacaa atactttttc ttcatacttc atttatactt gtcagtataa gagactgtga
    35641 caaatgtagt gatcctcaga agttaggtct ggaaatctaa cttgagaaga tttttttaaa
    35701 ctacgtccag tcttttttat ttgtttaaaa ttgaagttga caagtcttca ttaaaaattt
    35761 agaatattca caagtttgac gacaattatg aaaatttatg tcgtgctaaa ggagttttgt
    35821 tattggatga aaagttagat ataaaaactg cgatcaaaga cacgttacct accgtttttg
    35881 gttatatcgg tattggactt gcatttggta tcgttgggaa agctgccggg tttcatccgc
    35941 tggtcgtcac gttgatgtcc ctgctgatct atgctggttc tgcccaattt atcacggtca
    36001 gcatgcttgc tagccatagt ccactgctct ccatcgttct ctcgaccttt ctagtcaatt
    36061 cccgaatgat tctgatgagt atgacgattg ctccttattt caagaaaaat cggctgcttc
    36121 aaaatctgct gattggcaca ttgctgacag atgaaagttt cgcactggga atgaataaat
    36181 tgaactatac tggacaaaag ttaaactttc gttggatgaa tacagctaat tggatttctt
    36241 atttgacgtg ggtgggttct tctcttgttg gcgcactttt agggaatttt attactgatc
    36301 cgaaaaagtt tggtttggat ttcgccatcg tcgctatgtt tatcgggtta ctttatcttc
    36361 aagtcatttc tgatagaaac acctctaaac gattacagtt gatcctgatt ggtctcactt
    36421 tgattctggt atatgtcgga ctgattttta tcccaagtaa cttagtgatt ttagttgtaa
    36481 cactgattgg gtgcggattg ggggtgtgga tcaaacatgc cttcttttga gtttacattg
    36541 ctgactattt taggttgtac tttagcaact tggctttcta ggatcctacc atttgtctta
    36601 ctgaaaaaat tcgatttgcc gcaaccgttg cttgagtatt taagttttgt cccgatcgtc
    36661 attatgtctg ctttatggtt cagcagtcta tttacccaaa atatcggaca tctgccgcag
    36721 atcaatctcg aaaatgcttt ggcttcagtt cctacacttt tagctgctat tctttcaaaa
    36781 agcttattgg tgatcgtctt ggtaggaatt ctttcccttt cgttgattcg cttattataa
    36841 ataaaaaaac aagagcttat ggcaaattac tgtcatgcgc tcttgttttt atcaaagtca
    36901 aataagaaaa aaatcggcgt attcttgctt atccgttgaa cggaccacta acaacgactt
    36961 ttcctaatat atgtcctgtt tctacgtctt tggttgcttg tttcaagttc ttcgcattca
    37021 tcccatctga atagaccttg ctcaatgtac tgcggataat cccttcattt gctaaagcag
    37081 caatgtgcgc taaagcttct ccttgcgttt cgatttcata gttatagtct gttttagcga
    37141 acatatactc ccagtcgaag ctgatagatt ggtttttcca aacacctata tctaacggct
    37201 ctttgatccc tacgatcgtt cccacatgtc caaatggtcg gacaaggtgt ttgatttgat
    37261 caaagtagcg ggtaatatcg aataatacag cgacatactc tacttgatcg attcctaatt
    37321 cacgaaaact tttacttaag tcgtgatgat aatcgattgg atagtctaca cctgtttttt
    37381 tcagccattc aaaattcttc ggacttgcag tcgcgtagac ttctaggcca gcccaatgcg
    37441 ctagttgatt caaaatcgaa ccgacgcccc cagctccgtt gatcactaag atttttttcc
    37501 cgcggttggc attttcttct ggagtcagac caaatttttc aaataacaat tcataagcgg
    37561 tcaatgaggt caacggcaag gctgcggctt cttcatctga aagatttttt ggtgcaagag
    37621 cgacaatacg ttcgtcaacc agttggtatt cttgattgct tcctgctctt gtcgttgtac
    37681 ctgcgtaaaa aacgcgatcg ccgacagaaa atttttgcac ttcatcacct acagcaacaa
    37741 ctttcccgac tccatcaaac cctaagatac gtaaagcatt tcttatcccg ttatcttggc
    37801 gaagtttcgt atcgacagga ttaacagata ctgcgttgac ttttaccaga agatcccgtg
    37861 aactgggtac aggtatctgt tctttttcat caataaagct ttttggatca tcgatcgaca
    37921 acccttcata aaaaccgact accttcatta attccttttc tgacatacga attcctcctt
    37981 agcttcatca agttggagca tccatacagt tttcatttca atatatatag tatgctattt
    38041 gttccacttt tattcatcat aattattctc ttacttaaag taaactattt gcactttttt
    38101 ggttaaaaaa gaggttgcga caagactttt gtcacaacct cttttaaacg gtgttcaatc
    38161 aactgaccct cggtattcgc tcaaaaaacg acaaaatatg aggagctatt tttgtttggc
    38221 tgttcttatt acttgatgca ggacagcttt ttcacgacct ctaattcacg gtgttcaagc
    38281 aagaaatcat tgttcactga aaagcgttgg atgttctttt tcaaaggtgt ctaagatctc
    38341 tcgtacttca tcagtagatt tcgtattcat caactgaact cgcaagtcat ttgctcctgg
    38401 aaatcctttg atatagattt taaagaaacg atgtagtcct gtgatggaac gcgggatgat
    38461 ttctgaataa tgatcttgca gatctagttg cagacgaagt agtccgatca gttctttttc
    38521 tgtatgttcc ctcggttctt tttcaaatgc ataaggattc ttgaaaatcc cccggccaat
    38581 catgatgcca tctacgccat atttttcggc caattcttct cctgtctggc gatctgggat
    38641 atctccgttg atcgtgatca gtgtttgcgg agcgatttgg tcacgtaaag caatgatttt
    38701 agggatgact tcccaatgtg catctacttt actcatctct ttacgcgtac gcaaatggac
    38761 agaaagattg gctatatctt gatgaagtag gtgactgatc cattcttcca tctcagacat
    38821 ttccgtatag ccgatacgcg tcttgacgct gacaggcaaa ccgccagctt tagccgcttc
    38881 aatcaattgt gccgctactt ctgggcgaag gatcaagcca ctgccttttc cacgttctgc
    38941 tacattaggg actgggcagc ccatgttgat atcgattcct tggaagccca tttctgccat
    39001 agcaatgctc atttctctaa aaaattctgg cttgtctccc caaatatggg caaccatcgg
    39061 ctgttcatct tctgtaaagg tcaatcttcc tcgtacactg tcttttccat ctggatgaca
    39121 gaaactgtct gagtttgtaa actcagtaaa gaagacatcc ggtgctgctg catgctttac
    39181 gacatggcga aatacaacat ctgttacatc ttccattggt gctaaaacaa aaaaaggctt
    39241 tggcagctct ttccaaaaat tagtagtcat ttatttgtta ctctccattc tatcaagcag
    39301 tgaagtcgca atctttctca aaaacattgt cattatacta ggaaacaaaa aaagaagcaa
    39361 agtgaacagc ttaaaagatg tttctgattg agcaaaaaaa gactgtgaca aaaatcttat
    39421 cacaattcct tttccggaat aaatggtgtt caaaagcttg catctgcggt aataagtcca
    39481 accaaacgaa aaataggagg agctattttt gtttggctgt tcttattact tgatgcagaa
    39541 cagctttttc acaacctctc cactaaacgg tgttcaatca gctgaccctc ggtattagct
    39601 caacaaacga caaaatatga ggaactattt tcccgtttgt ttctctaata ctcaggtcaa
    39661 aacgctgatt tcacaacctc ttttctaact tctcaatcct cttcctttat tgatcaaata
    39721 ccaagtaacg gcgtacaaaa caacgatgaa tagcacaagt acgatcatcg atgttgctac
    39781 tggcacatcg attgttccaa ggaatccgta acggaaaccg gagatcatat aaacgatcgg
    39841 attgactttc gaaacagctt gccaaaatgg cggcaacata gagatggcat agaaaacgcc
    39901 acctagataa gttaacggct gcaagacaaa tgtaggcacg atcgatacat cgtcataaga
    39961 ctgagcaaaa atcccgttga gcagtcctgc taacgaaaac aagattgccg tcatcaataa
    40021 tgtaatgatg accatgaacc atgaatacac atgaagtggt acaaagaaca aggaaatgat
    40081 cgttacgaga gagccgacga gaatactgcg acccactccg ccaatcacaa agccccaaat
    40141 gatcacatgc gtaggaacag gcgctaccaa gatttcttcg atgtttttct ggaatttttg
    40201 agagaagaag gacgaagaaa cgttggcata cgaactagtg atagcagaca tcataatcaa
    40261 accaggcacg atgaattcca tatatgaaaa accacccatg tcaccgatcc gaccaccgat
    40321 catttttccg aaaataacaa agtacaagga tgtcgtgatc acaggcggaa ccagtgtttg
    40381 gacccagata cgcaaatagc ggttcgtttc cttgatagct aaacttttta atgcagtaaa
    40441 ataaagatta aacatttttc tcctccgtat gattattttc ttctgtgatt ttcaaaaaca
    40501 gttcttctaa acgattcgac ttattcctca tagaaagaac tttgattcct tgtcttgtca
    40561 gctgatcgaa gattccgttc accccttgat ttcgttcaac ttcgacagcg attgtctgtt
    40621 catcttcaaa tgtacaagcg tatccttcaa tcacaggttt ggtctcatat ggcgctaaat
    40681 caaagataaa tgtttcaaat tgcagtttgg atagaagctc tttcatacta gtattctcga
    40741 tcagttcacc tgattggatg atcccgatgt tgcgacaaag catttcagct tcttctaaat
    40801 aatgcgtcgt caaaatgatc gttgtaccat tttcgttcaa ttctcggaga aactcccaca
    40861 tctcgcgtct caattcaata tcgactcctg ctgttggttc atccaagatc agcaaacgtg
    40921 gttcatgcat caatgcccta gcaatcatca gtcttcgctt cattcccccg gaaagcatac
    40981 gtgcacggac atttctcttt tcccaaagat tggactgctt caaatatttt tcgctgcgtt
    41041 tcatcgcttc tttgcgagag acaccgtagt agcctgcttg attcacgacg atttgctgga
    41101 ccgtttcaaa gggattgaaa ttgaactctt gcgggactaa tccaatctgt tgctttgctc
    41161 ggactagatc cgtatccaga tcataaccga agacattcac ttttccagat gttttattga
    41221 ctaaagaagt aatgattccg atcgttgtag acttcccagc tccatttggt cctaatagcg
    41281 catagaaatc tccttctttc acggaaagat cgattcctcg caatgcttcg accccacttc
    41341 cataaacctt tttcaaatta tttatttcaa gcgcatttgc catttatttc ctatctcctt
    41401 atagacatga ttctttattg tatcatggaa tacagcagat gaaaaaacaa cttggttcca
    41461 gcgaaaaatc aggttgctgg gctcaggaaa atctcctaat gaaagacatc aatcggacga
    41521 agtcagacaa ccttttcaga aaaaacaaat cgaagataaa ggattactat tcatatgtgc
    41581 aacaaaagga gcgtgagaca aaagtaaaga acacttttgt ctcacgctct aaacacgtat
    41641 aaacggcgga agcaaaagcc aagatttttg atccaataaa tactttcgat cacttcgcct
    41701 atcccaatac atgccactgc cgcttttcat caaataacgc ggcttccgtt tttgcggttt
    41761 ctactaaagt ctctgggtaa tccaaaactt tcagcaaggc aatcgcattt cgggtccttg
    41821 aaggtccttc ttttaatttg aaatcaaaac tgattccttt tccttctgtt acttgttctt
    41881 caaagtggac attctcacaa taattcttta aaatctctgt caattcgata tcatgtgtgg
    41941 cgacaaatgc taaagatgga tactccgcaa gccaccgaac gactgaagcg gaagaagcaa
    42001 tccgttcgat cgtatttgtc ccttttaaaa tctcatctac gaagcagtag cagcgttctt
    42061 tggaagccac ttggtccaac aaacgtttga tcgatttgat ttctgaaaca aaataactgt
    42121 cgccttcaaa taaatcatct tcgattgcca tggaagtcaa cacatgtcca ggttgcaggg
    42181 taaactgttc tgcaatcgct gtttggatcg tctgtgctag aatacagctg atggctatac
    42241 ttttgacata cgtagatttt cctgatgcat tggaacccgt gactaatgta ttcttctgcc
    42301 agttgaccgg attcactacc gcttctttta acaatggatg atagatatct ttcgctgtca
    42361 caccgccctc agtaaactct ggtcggcaag tgatgggcat ataagtacgg taattcaata
    42421 ttgcagcggc tacttctaat tctcccagca attcccacag cttgatggct tcagttgaat
    42481 gcttttctaa tttagtgaga acgaaatgat aggagataaa tggcagcatg aacatgatgt
    42541 tgacatattc aaaaatcaac tctgcttcac tcccactctt catacgaaat gaaaaaccta
    42601 atttagggat gtctcttaat ggtttagttt gctgtttcag ctcttcttga agtggtgtcg
    42661 gcagttttgc tagctgattg gcggctgaaa tcgttgaaac caaataactc atgctattca
    42721 gctctgtttc tagtgtttgt ttcttcacta gataatagac cgtattgaat actaacccac
    42781 cgattgccaa atagattcct agtacttgtc ctaaaagaag caaacccaaa cccaccagcg
    42841 gaagcaagcc aagaaaaata aataaaccta cgcgtccaat ctttttactt tttccatccg
    42901 ctagatattg ttttgcaaaa ttatgatctt tttttcctaa acgagcgaat tgatattgga
    42961 ttttttctct cagttgagga ttttcctgat aaaaagcaat cagtttttct aactgctgat
    43021 cttcaccaaa atcaaagctg cgtaaacgtt gatacaacgc ttctgaacct acactagaat
    43081 aggtactgtt gattccttcg aatacttcga acatatccag gtcataccaa gtaagatcat
    43141 cgatttcgct atcccatgaa cggaacttct tctccgtgag ccatgcttcc ttcaagcttt
    43201 cttctttatc aaatctcggt tgataaggaa ttttttccca tttgctacga actgtttcct
    43261 ttaatttcaa acgtgaaaaa atgtctaaag caactaataa aataacagct gcaataataa
    43321 ttaaaacgat aaattctctt tgacccatat ccctctccgt tcctttattt gttagcttta
    43381 gtatagcact gttgcgctat ttgaaaagag ggtaaaaaaa cacctttcaa aataaaaggt
    43441 gtttttttct tgtatattac atatttatct ctcatttatc aaaattgaca aataatcata
    43501 gggaggaatt gttgttaatt cttgtttatt ctccagtgca ttgacaactg tcccaaggga
    43561 aaggatagcc tcaggtacta ttttttcttg ttctgttgga ttagctaagc gaagaacaaa
    43621 tccttgttca tgaaaataag aaggataaat cgatgataca attaagtctt caggtaattc
    43681 aatcaatgaa aatttacgag gaacatcaag ttcattttgt aatggccaaa tcttgttatc
    43741 taacctgtga ataaatacat tcagtttctg cttttgataa gaaatagatt gttctaaccg
    43801 tttttctgcc tgttttgcca ctttgaactc attaaatctt ccttcttcta cattaaatcc
    43861 aaaagtgact ttatactcac ctatctcttg agctagcggt gtttccatca tgacatgccc
    43921 ttcatttgtc gtatctcctg aagctcgccc aggtcgccaa gcaagattag gttttccaag
    43981 ttcccctgtt gttgaaaata aggttatgat taattgattt tctatacgtt catactcttt
    44041 taaaccatct gcataaaacg taaaataatg atcattttct gccacagaga cactcttatc
    44101 gaatatttct aaattaacag gtttctctac catagtttct gaccaattcg gaggaatgac
    44161 atcaggggta ttttcaataa atccgttttg aatttgtgca attgattttt cagatttatc
    44221 taaaacatta attgctaagc gcatacgatg cgagtaaaca gtattatgaa ttttgagtgt
    44281 gccttcaacg atttgacttt ctcccagact gaacgatatt tcataagata tttcttccat
    44341 ttcgggtttt tcagataaac gatcttttaa atctttagga agttgagctt ttccgtaaac
    44401 aactaatgtt tcttgtaaag aatctttata tactttagct gtttctaatt ttagagatag
    44461 ttctgtatct ccttctaatg gtgaataatc atacgtatcg ccatcatttg ctgaatcgat
    44521 caaatgaacg aaatcaagat attgtctatc tccaactatc aaattcaatt gcccatcttt
    44581 aaaagaaagt ttatatttat tgttacttat ctcagttttg tctatctcga ttgctgtttc
    44641 taatttttca ttatttttct caaattcaac aacagtgtat cctagtgctg gcacatttac
    44701 atttattttt atgtcaagtt cataataagc tggttcatca aaatattcga aacctgtagc
    44761 aatcatccga taagcatttt tccgttctgg aaaataaact tctttttcaa tgatattata
    44821 gggactacct ttgaagtgta ttttctttga atcagctact acatgcacga ttttcgatcc
    44881 actataattc tcagtcgttg tgttgaaaac aaggacttca ttcgatttta gctttaatgc
    44941 atcagccatc cgttttacaa taaggttttc gattccgtca gctatctcat tagcttcttt
    45001 gattcgatgg aaaatatctt ccgcaacatt atctgaaaca cagccaccaa tactatcatg
    45061 agcctggttt tgcaaaatct ttttccataa ccgacgaagt aggcctttac tgatatggat
    45121 accatttctt tctgcaatca gcatgagcgg ctcaactcgt tttagaattt tttgttccaa
    45181 tttaaaattt tctattttca tttttgttct tactgagcca atagaacgat gaacacgaga
    45241 gtaaaccggc tgacgaagtt cacctttata ttcaggtaat tcttttttgt ttctgataac
    45301 ttctacataa gaaggataat ctgaaataat attgtggaat ttactgtatt tattcaactt
    45361 ctctacgact tgatcaaaat ttaaaatcat tgacttttga tctacacccg aaggtactaa
    45421 aatatctttg ttttttcctt gcatatgaag catttcaact gcttcatcca acttttcttt
    45481 tgcaaattca ggaatatctt taattgcgtc taaggtcatc attccagtca tataaccaaa
    45541 tggaaaattc atggcataaa caaatttatc tcccaatcct ttccagataa aataaggaga
    45601 tggaaccatc gtttcaaagt ttaatcctcg ccaacacatg aaattatcga tttctacttg
    45661 atgcaaaagt gtaggcaaat tcgcattgaa cccaaacgtg tcaggcaaat accctaccat
    45721 cattggatct ccatatttaa ggatcgtatc actgattcca atcattaagt ttcttaaaat
    45781 tgattcagca tccactaata aggcatctgt ttgtgcatac cacggtccca cgaatagttg
    45841 tcctgttttc atcagtcgtt ggataacctt aagcttttgc ggattgatct ccaaatactc
    45901 atcgacgatt gaagtttgtc catctaaaca aaagtttact ttagggttcc tttccaattc
    45961 atctagaact tcagtaaaga cctgatcaga caatacgatg gcatcttcat ttgtaaaata
    46021 ccattctctg tcccagtgcg tgtgttgaat tatatgtgca tttaccatat cagattctcc
    46081 tactttcctt cttctactga atttacttgt tgttcttttt tatacttgat ggattttagt
    46141 gcattgacca ttaacgctgt aaccactccc ccaataacaa ttgatactaa atataaaggt
    46201 atattcgtaa caaaaggaat tgccataaag gttgaaagca ttgtttcttg agtaacacca
    46261 aaaaatccat ttagaccaca tgctactgca gtgcccacca cgatgcttgg tattactcgt
    46321 aaaggatctt tcacggcaaa cgggatcgtc ccttcagtaa tccccacaag gcccataatc
    46381 atagctgtct ttgcattatc tcgttccgat tcatcataaa gttttttgtt taaaattgtt
    46441 gctaaaaaca ttccaaatgg cggaatagca attcctaata acatggctgt actaggtcca
    46501 aagcttccgc ttgaaaaaga agcaacccca aaagcatatg cgattttatt gataggtcct
    46561 cccatatcaa acgccatcat tcctcctaaa atagccgaca tcaaagcagc atttgctcct
    46621 gacatgcctt ctagccaatt agtcagtcct gttgtcattg cttgaatagg cgtagctagt
    46681 acataccata atatgattcc aacaactaat gtagtaacaa aaggaatcag cataattgat
    46741 tttagactaa taacttgcat cggtactttt acttttttca atgcattagc taaatagcca
    46801 caagctaatc cagcaaccat tcctccaata aatcccatac caagattttg acacatcatc
    46861 ccagtgataa aagctggtgc tagaccggga cggtcagcaa ttgaatatgc gatataggct
    46921 gaaatcatcg gtacgataaa ctgtaatccc gtctgaccaa tcattcgcag gactccccag
    46981 aatgtatccg tctggtccca aacacctgtg ccaccaaaaa tgactgcaat agaagttagt
    47041 aaccctgctg ctacgacaag cgggatcata taggaaaccc cactttggaa atgatttaga
    47101 atttctcttc cttgtttctt gaattccatt agtaactccc ccacgatata ttttttattt
    47161 gttaattaat gcaattgctt catcaatcgt ctcttcacca tcttttacta cctctgaggt
    47221 ccctactgtt aaaatcggtt taccgtcaaa gcgacctcgt tctgaaacat ttgtatctac
    47281 tgcaaatatg acaacatctg cctcggaaac atccgaaatt gaaagtttgt tttctatccc
    47341 catagccccc tgtgtttcta ctttaatatc taaccctttc ttcttcgcaa acttttctaa
    47401 attagctttt gccatataag tatgggcaat ccctgcgata catgctgtta ctgctactat
    47461 ttttgtcata tgaaattcct ccttttaaaa tgatagagct tttaccaatt cttttttatt
    47521 tctcgaatct tttattcttt taacaaactc gtcatccatc aatcttccag ataattctgc
    47581 taaaatacgt aaatgattag tacctttatc agtgtctttt attgctaaca aaaagacgag
    47641 atcaactggt tgatcatcta atgcgcccca ttcaacagac cgctttaact tggctacagc
    47701 cactgttgat tcaattactg ctaggctttt gccatgagga atggcgatat ttttcccaat
    47761 tcctgtggtc atatggtttt ctctgtcaaa tacgtctttt tgaaattgtt tgtggtcaga
    47821 cacaaaccca ttagtctcta acaatttcga taatttttcg actacacttt ttttatcaga
    47881 tgcatttaaa tctatcacta tattatttat attgattttt tcactgatca tttataagcc
    47941 ttctttcaat atataaacta atttttcaaa cgacgaactc gtttttaaat ttgctaataa
    48001 ctcatgattc gaagcgattt cattgaatgt ttcataaatt ttattcaatt caggttttac
    48061 tttttcatta agtgcaaaaa agaaaacaga atgaacaagt gtcccatccc aatcaattcc
    48121 ttctggatta acgtagacac agattactgg cttttttata aaatctactt cgatatgcgg
    48181 catagcaaaa tcattcatcg ctgttgaaga tagtttttct cttttgattg ctccctctag
    48241 tatcccttct ttcgcgtaat tttcttttac caattttttg gtaattatat ttaaaacgtt
    48301 cacttgatta tcctttattt ggtgggtaaa aaagcaaaat cgtttatcta ataaatttag
    48361 aaaagcatct tctgtttgtt catttaactg tagatactgt tttacttttc tgacatctgc
    48421 ccctaacatc aaaggactaa caacaataac aggaaaattt gtattttcaa tcggaatcgt
    48481 gcttataaca agttcatcag tgacttttct atcttgtagt tcattgatgc ttagtacatc
    48541 ttctatctca accatatctg caaaaccgtt atttattctt tgctctaata attttgatgt
    48601 tccatatccg ctactacaaa ctaatatcac tttcgttttg tcaggtttgt aacgatccaa
    48661 aagtgattga atatggagtg ttacgtaagc gatttcatct tcattaaaat gtatacagaa
    48721 tctctcttcg atttcctcta ataaatctac acttatcata aatgaccttt taaaagaata
    48781 tttgattttg tccgtataag ggttatagat atttactccc aatttgagtc ttttaactgc
    48841 tgcattgaga tgtaatacta gattattgat caattcttca tcaggataaa attcatttaa
    48901 tttaattctt actaactctt gtagctcaac acccatatct aaataggaaa gcttcgtttg
    48961 atctaagtcg tgattcatag catttttttc aatcgaagta atgtgaatgt caacataagc
    49021 ttgttcatct attggcacaa taattgaaaa tgctttttca atcattttga ttaaaataag
    49081 tgtattcttt gagatttctt cttcagaatt attactacgt gataagaaat tgcttgtttc
    49141 aatcctttct atcgcaatag caaggtggat agctaaagtt tgaaattcat aatctgtaaa
    49201 tttcaattgt gtcttattca tgtatcgatt aagcaattcg gctacttttt tcaatatgtc
    49261 cttatttaag aaattattcg cttcaccaat gaaattgata ttcaagtcta agagatctgt
    49321 tttactgtta gatgctgtaa agccacccca ataatagttc acaacttctg acatcaacct
    49381 tcttttactt ttttcatcag ctttgatgcg cacgccattt cgatctgaaa ctaaggacat
    49441 cccatgcttg tttagtcttt ttctaacatc tttcattgtg ctttctaccg tcgacctgct
    49501 cacgtataat tcgtcagcaa gattttgaat ctttagagaa tcattagtat tcaataattt
    49561 agcaaacaca taagttagac ggtcctccgg agagtctgcg atattgattt tatgactgga
    49621 taataaattt cgaagtgttt ctttttttcc aataagcgaa acgccttttt taggttgaac
    49681 caacatttgt acatctggca ttttttggat tatttctttc aaaattaaaa tatctttgct
    49741 aattgttttc gtagatacat ataattgttc tgataattct ttgtaagttg tgtgctcatt
    49801 ttcaatcaaa aagtatagta ttttcatttg ccgttcgcta aattcgatgc ccattatctt
    49861 cacctcctga atacagctta agtgtacaat tattatctct attttcatac agaagaaagt
    49921 tcttgattaa tgtagaagtt tctaatattc ttgattattt caaatcaata aaaaagcctg
    49981 caatatttat atcacaggct tttttctcta ttaaatatat ataagataat acatttttct
    50041 actagttctc actaatcttg tataattaaa ccctccgcaa cttgacggag atggagaaga
    50101 tgcccccgtc taatctagcg gtcatctctc ctcccattcc ttccaccaat ttttttgaca
    50161 ggtaaagccc gattccgcta gattccgtat ttgtgcggct ggtattttcg gtataaaaac
    50221 gctggaagac tttttcaaca gaggtttgcg ttcctggttt gataggattg gccactgtta
    50281 atcgaatgaa tggatcctct tttgaaaatg tcacctttgc ttgtccatct gcataacgca
    50341 ataaattctg tatgatattt tgcagcactc gcagcaacat gagcggatct gctaatacag
    50401 ttgtatttat cgagtgttca gcgaacgcta cctcgatatt tttctcagaa aattgttcat
    50461 aaaaagagaa aaatacttct tccacctctt tagaaaaaga aagcgtatgg agatccattt
    50521 ctttttgctt cgtctctatt cgagcaagat cataaaactg atccgtcata ctgagtaatc
    50581 ttgcaacaga ttgtttgatg atcgttaaat acttctcccg tttctccgta tcctctacct
    50641 gttccagtaa ttgtacataa ccgttaatag cagtcaaagg agttctgaga tcatgagaaa
    50701 ggccgacgat cgatagtctg atgttttctt ccatttcttg aaatgcttgt cctttttgtt
    50761 cattttcatc caaccatgta ttcagtgcat ctactaggtc cattagattc ttttctcgaa
    50821 attcgactga aagacgacca ccatattctt gtcgttcaga aagagtggcg attttcttag
    50881 ttaatctctt gatttccctt tgcaggaaga aaataaaact tcccataaag ataacaacga
    50941 gaagcaacag ccatttaatc aaatctaaac cccactcccc acaccgtatg aatatacaca
    51001 gcatgtgcct ttgctagctt ccctcgaaga ttggaaatat gcatattcac tgttttctca
    51061 ctatcaaaat atggttcttg ccaaactgtt tcataaagat ttgctcgcga aaatactttt
    51121 ttcggatgtt ctaaaaaaag cttcagcaga tcgaattctc ttcctgtcaa atggacagcc
    51181 acaccattca catttacatc cctcgactct ttgtccagta agatttcctt gtaatagatg
    51241 cgttgcgaca gatcttttac ttggacagaa gtctgatgac gaagttggat gccgattcgt
    51301 aacaaaagtt cttcgatatc aaatggtttc gtcacatagt catccgctcc tgctgccaac
    51361 aaggaaactt tatctctttg atcgcttttt gctgaaagaa cgatgatcgg aacattcgat
    51421 gtctgtcgga tttctgctaa caatgcttca cctgaaagcc ctggaagcat gagatctaga
    51481 aggatcaaat cgacaggata tgtgcttaac aataattttc cttccgtacc tgaataagca
    51541 tcaagaagtt tgtatctctg ttcaagaacc tcctccagta aggaatgaac agcttcatcg
    51601 tcttcgataa tcaaaatagt ttccagcagg accacctact taatgtcaga tttttggaaa
    51661 ataaacattc ctagagctga tgataccacg attgttacta gactgaccag aatcattttc
    51721 ggtgcttgcg aataagttgc ttgttgcgca aagtccgtat acatgagcca cgtttccgta
    51781 aaccactccg ttagaaattc caagcctttg atttttgcga aaacaccggg aatgaaggcc
    51841 gttcccatga tataaagaaa agaaagaagc aaactgacac tggtacttct agtgatgaat
    51901 gtcaaagcca ctggaacaga taatgtccct aatgtcagca gaagcaatac aggaaatact
    51961 tttagaacat aatttccata gtttttgatt ccctcaactt caccaaatcc gaaagcaagt
    52021 gtgtaagcaa gcatggctag tcccgtgatc aaaaccacgc caagtgttgt gatcaaaagc
    52081 gtaacgagaa gtttcgacac ataataagtc attcgattcc gtcctaaaga taacgtattg
    52141 cgaatcgtac cgttttgaaa ttcttcccca atataaaagc acgcaaatgc tgcgaaagcc
    52201 agaagaatcc atgcagccat tttttctacc attaaaatcc ctgttgcacc gttgatgact
    52261 gtatccgttg cttggtttaa ttcattgccg tattttgtat gcatatacca ttcgttccaa
    52321 gaataaaaaa gcggaagtac gaccatcagt cctagtgaga cccacatttt acggctcttc
    52381 catactttta ttttttcagc agttaataga ttaaacatgt ggattgcctc cagttaattg
    52441 taagaaataa tcttccagtt tttgcccaac taggtgaata ccatccacag gaacttttgc
    52501 ttctaccaat gcttgattga tggctgctac ttggtcaatt ccttcaaaaa gctggataac
    52561 acggctagat tgtacaaaat aatccctata accaagagag tcgagaaccg ttactgcttg
    52621 ttccgtcgcc gaagtgtcaa tttttataaa ttgacgagat tcttgtgcca attcttcttt
    52681 cgataattct ttgatcaagt gtccttcatg caaaatacca tagtgagtgg cgatctgtga
    52741 caattcatct agcaagtggc tagaaagcaa gacggtgatg ccccgttctt ttaccaaacg
    52801 ttggatgatt tctcgcattt ctgccatccc tgctggatcc atcccattcg tcggttcatc
    52861 caaaatcaaa aattctggat tcgtgatcag tgcatttgca atagctaaac gctggcgcat
    52921 acctaaagag aaattctttg ctttcttttt ccctgtattt tccaatcgca tcattttcag
    52981 caggtcttcg atttctctat ccgacacacc gccgttcgct gcttggatac gtaggttatc
    53041 tcttgcagtt aattctggat aaagagcagg ggtttcaatc gattgaccca tacgtcgtct
    53101 tgctgcctgc aaatccgtcg ttccaaataa ttcgatcgaa ccttcatcaa tcgagatcaa
    53161 acccataata gttctcataa aggtagactt acccgctcca ttttccccaa tcaatccata
    53221 gatcattcca cgtttgattt cgattgatac tttatctaat gctttggcag caccgtattt
    53281 tttggttata ccagttgctt tcaagaccgt ttcatttcca aaatccatac ttatccttct
    53341 ttcttattga tgagtgaagt atagttgacg ggtataaaga aagcagccag aaatgtataa
    53401 agaaagtgta aattttccaa ttgaatgtca aaaaaaacaa tcggacaata cgtgtctttc
    53461 ctattatcag gcagtttgtt atacgcttgt atcagtttcc tgattctttc ttttcgacca
    53521 aagtcgtttc tctgtattcc tcttcactga aaatttttgc ttctttcaga tcaagcttga
    53581 gtaattttac cagaccggtt ataaggataa ctatagcaag actccctccc agaaaaatta
    53641 gactgtctcg cagacgtggt tgcgttgtct tccaatcaaa gagcgcacca aacagtgcta
    53701 atccaagtgg actggccacc atggtaatcg ttgttatcgt tgacataagt cgtccttgta
    53761 tatgcgttgg aacttctcgc tgaagccaga ccatataaaa agcaaaagaa aacattaatc
    53821 cttaaaaacg gacttatgaa aaataataca tgccgtttgg gatttacaat tagctaccaa
    53881 ataagaggtt atgacaaaag acttttcaca atcccttctt ccgaataaac ggtgttctcc
    53941 tgccaactcc tcggtcacaa gtcacaatat ttatcaaaca tgagaagcaa tttttgtaaa
    54001 ttccttctta tttcttgaag ctgaccactt ctgtcacaac ctcagaagcg gataaataat
    54061 attgtttgat gatactttat ctttttcccg tttgtttata gatcgaatga tattatagac
    54121 caagaatcct acctattaac atagctaaaa acacaaaaaa ggcactttcc aaattgtgga
    54181 aagtgccaga aaagttagga ttaaggtaac tgcgctcagc attgcttcgc ccagtacgat
    54241 tctcgtaact cgtgaactcg aacgataatc gcaattaacg ttttgagaac tgtgaagctt
    54301 tacgggcttt cttaagacct ggttttttct tcgtatcatt gaataagttt gaaaaacctt
    54361 gatttataaa ggttttcccg taaatatatt ttattatatt tgattaaatt tgaaatgttt
    54421 gtgttctaaa atgtgttcta atttaaaggc agtatatttc gtattttaga ttaaattttt
    54481 aggctcattc attctcaaat ccattctatt cagtcaataa aaattttaaa aagactttat
    54541 aaacaaagat gttcaagcga gcatcttatt tttttgtgct taatttgaaa ggagaacatt
    54601 tcatgtataa aaaacaaaaa aagaaattat gtgtattaac tattttgagt ttggctgttc
    54661 aagcaattgt tggagcaatt gctcctacga ttacttttgc tgatgaaatt acccatccac
    54721 aaacggtaac cgtagaacta gatttagcac atcaatatgc tgttgaagga acttttagtg
    54781 atggtcgtcc aatgtcagaa gtcactgttc cgcattatgc agtgtacaac ggctttaaac
    54841 aagatatttt ctgtattgaa ccaggagtcc cgatttacaa tgagttcact cctggctatg
    54901 agaaaaaccc gttaccagat atgtccgata aagccaaatt agtttccgtt ttatggaaaa
    54961 aagtaggtac agatgcagat actcatattg tggcacagaa gatgatctgg caagaagtta
    55021 atgggtatac ccttcactca ataaaacgat cagatggtag tgccgtaaat atcgcagcca
    55081 ttgaggcaaa aataaatcaa gccattgacg attatcagaa gaaaccaacc ttccataata
    55141 gtacggctaa aacagtatta gggcaatcga ctactgtgac ggatacgaat aatctgaatt
    55201 tgtcagagtt cgatgaggtt gtggaaaatg ccgcaaacat tgattatcgt gtgaatggta
    55261 atcagttgat aatcacccca aatgccaatt caaaagaaag tggtgtgctg acgcttaaga
    55321 aatctgctgg taccggaaca cctgtcgcct ataaaaaggc tggccaacag actttaatgg
    55381 ccggggcgat tgataaacct aatacctaca caatcaaaat tgatgtggaa acggagggtt
    55441 ctttaaagat caaaaaagtc gataaagaat cgggtgatgt tgtaccagga acggttttcc
    55501 atttagactt tggaaaaact ttacctgcaa aagacgtgac tactgacaaa gaaggcattg
    55561 ctacattgga tgagattcct catggtacaa aagtaaccat taccgaaaaa tcagtaccgg
    55621 cgccttatac gattgatacc acccccatga ctaccaccat taaagcaggc gaaaccattt
    55681 acgtgacttc aaaaaacgca cgggaaaaag ggcaaatcat tctggataaa agcggagttg
    55741 aaacagggag tgatctttgg aatgacaatt attccttagc tggtaatacg tttgccattc
    55801 gcaaagacag tccaaccggt gaaatcgttc aagaaatgac cacggatgaa aacggtcatg
    55861 cggaaacacc aaaagagatt gctaatgcgt tggaattggg aacctattat gtgaccgaaa
    55921 ctaaagctag tcatgggttc gtgaatacgt tcaaacctgt aaaagtcgaa ttgaagtatg
    55981 ccaatcaaac cgtagcccct gttaccagta acgtaaaagg gcaaaatcaa gaagtcactg
    56041 gcgaaaccac tttgacgaaa gaagacaaag atactgggga taaagcacaa ggtaaggcag
    56101 tctttgaggg tgctgaatac accttgttta ctgctaagga tggaaaagct gttaaatgga
    56161 gtgaggcttt taaaccagag ttagcgaagg gaacgaaagg ttctgatgaa acggtcactt
    56221 tgactttaga cgaaaagaac caagttgccg ttaaacattt agctatcaac gagtattatt
    56281 ggcaagaaac aaaagcgccc gaaggatata gccttgatga aacaaagtat cctgtatcca
    56341 tcaaaaaggt ggatgatagc gaaaaaaatg ccgtgattac ccgaaatgtt acggcaaaag
    56401 aacaagtgat tcgctttggc tttgatttct ttaaatttgc tggatcagct gcgggcacta
    56461 ccgaaactgg cttcaatgat ctgaccttta aagtgtcgcc attggaaggg accaatgaaa
    56521 tcacaggtgc cgaagatgaa gcgaccacag cttataacga gcaattaggg tttgatggtt
    56581 atggcaagtt tgaaaatctt ccttatgggg attatttact tgaagaagta gaagccccag
    56641 aaggttttca aaagattacg ccattagaaa tccgttctac ttttaaggaa aacaaagaag
    56701 actttgtgaa gagtgagtat gtctttacca ttaccgaaca agaccaaaaa caaccaatta
    56761 aaacggtgac cgttccttac gagaagctga cgaacaaagc attttctgtt agtttgaacc
    56821 gtttaatgct ctatgatttg cctgaggaag aagatagttt aacttctctt gcgacttgga
    56881 aagacggaaa caaagaatta acttctctgg attctaccga gctagttgat aaattgagtt
    56941 acaatctaca tgaaatcaaa gaagactggt atgtggtagc gcaagccatt gatgtggatg
    57001 cgacaaaagc tgcccaagaa aaagatgaaa aagccaaacc agtggtgatt gcagaaacaa
    57061 gcgcaacgtt ggcgaacaaa gagaaaacag gaacttggaa aattcagcat aaattaaccg
    57121 ccgaacaagt tttaaataaa actattgtct tattcaacta tgtgtatgaa aataaggaag
    57181 cttttgaagc aggcgataag ccagtagcga aggatgttag cttgaataac caagcccaaa
    57241 ctgtcagttg tacagtggaa caccatgttt ctatccaaac aaaggcccac ctagaaaacg
    57301 gttctcagac ctttactcat ggtgatgtgg tggatatgtt tgatgatgtg tcgattactc
    57361 atgatgtact ggatggctca aaagaagctt tcgaaacaat tctgtatgct ttattaccgg
    57421 atggtacaaa caaagaaatt tggaaatctg gcaagattga ttatgaagta aatgataaag
    57481 aattcaccaa aactgtgctt gcgaaaaaag tagataccgg aaaatatcca gaaggaacca
    57541 agtttacttt tgcggaaatc aattacgata aagatgggaa tatcaatgga aaacacaatg
    57601 aagatttgaa agaaaaatct caaaccttaa caccaaaaga agttccaacc atactaagta
    57661 cgccgaaaca accggaaaca ccaactgttc caagtggctc tcaagaatct agtcccacag
    57721 tgaagacctt ccctcaaacc ggggagaaaa attccaatgt tttactgttc attggtttta
    57781 ctttgatttt tgcgacggcg ggctattatt tctggaatcg ccggaactaa ggtgatgaga
    57841 tgatacaagt aaatcctaag aaccaacgtg cgcgaccgcc tcctaaaaaa gtagtcgcgc
    57901 tatttttgta tccaaaacta acaatgaaaa gaggaaaaga agatggaatt gaaatttgtc
    57961 gtgccagata tggctgaaac ctttggaaag ttaagttatg ccggtgaagg agaaattata
    58021 acagaaggat atggacggaa tactacggtg attggtcgca gttatcattt gtattccagt
    58081 aagcaacggg ccgatgatat tgaggtggta gtagctgcgg aagccggtga aaaggatttt
    58141 gatcaagacc aaccgctaaa agccgtgaat ccccatttgg ttgccaaagg ctatgagatt
    58201 gagaatcgtg ggtttactga ttacgtgttg tatgttgatg atttagtgaa agcataggag
    58261 gaaaagaaga tgagattaac agaaggtatt gtcgtagatt caggtttaac atttgggaag
    58321 ttgcgttttt ccgcattacg ccgagaagta cggaagcaaa atgaggatgg aacaattggt
    58381 aatgaggtaa aagaacgaac ctataattta aaatcctctg cacaagggcg aatgattcaa
    58441 gttagtatcc cagctaatgt acccttacgc gagtttgctt atgatgcaga ggtagagttg
    58501 gtcaatccaa tcgtggatac cgttgccaat tatgtttttc gagaaggaac taccgttaat
    58561 tggttcatta aggcggatga tttagtcttg aagcggcagc cgaatcaagg aaatcctacg
    58621 aaccaaaatg aaagaaagaa ataggtgaag attatggaaa ttaatgttga acatatttta
    58681 gattgtctcg atcaatatgg aaaaggcgag ctgactgagg aacaactcgt taaagcatta
    58741 acctctgatg aaaaaatgtt tctgattata catcaaggtt tacttggaga aaatagcgac
    58801 agtgaagaag actctgatgt actagactgg ttaggagaag aagagtcttt ctttatagtt
    58861 gtcgaagtaa atgaaaactt atgtcggcag gcagaatcca ttttggaaga aattggtgtg
    58921 gagatgccgg atgctattga aggcttttta aatcaattgg ttgaaacgaa acaactcccc
    58981 tcctcgtagc agtaaatgac tagcataact ttttgaaatt gcctaatgaa atcctattgg
    59041 gctttttcga ttggaggtgg aaaccatcaa aatgtacaaa ggacatcgca tacgcgcagg
    59101 agatcagcac ttggtttatc actttgttct tggctggcta ctcgctctgt tcatcggttg
    59161 gatgagcgtc ttttattttc aagagtttag acaatttgat atttctaagc tatcactttc
    59221 tactattgaa atcgtttggt ctataaaaga tttagtatgt ctgcttggaa gtctcgcttt
    59281 ttcaggagct atgatattgc tttatattca cttttttctt gatcattggc gaagcttgtg
    59341 gcatcgacaa aagctagctc ggatgattct agagaaccat tggtatgaag tgaaacaaac
    59401 tcaaagtgaa ggctttttca aagatttgaa tagtagccga accagagaga ctatcagtta
    59461 cttccccaaa atctgttatc gaatgaaaga tggattactg tctattcgcg ttcaaatttc
    59521 acttgggaaa taccaagatc agcttttaaa attggaaaag aagttagaaa gcggactgta
    59581 ttgtgagtta gtagaaaagg aactcaaaga ctcctatgtg gagtatactt tactgtatga
    59641 tatgatcgcc aatcgaattg ggatagacga agtagtggca gaaaatggga ctctgcgatt
    59701 gatgaaaaat caagtatggg cttatgattc tttaccccat atgttaatcg ctggtggcac
    59761 gggtggaggg aagacctatt tcctcctcac cattatcgaa gcactattga agtcagatgc
    59821 agaattgttt atcctcgatc ccaaaaatgc agatttagct gatttaggta cggtgatgcc
    59881 tcatgtttat tcacaaaagg aagaaatttc tgcttgtgtg gaagatttct atgaacgtat
    59941 gatggctcgt agcaaggcaa tgaaagaaat gtctaactac aaaacaggag agaattatgc
    60001 ctatcttgga cttccaccca actttttaat ctttgatgaa tacgtggctt atatggagat
    60061 gttaacgacg aaagaaagtg cggtgatttt gaataagctc aaacaaatcg tgatgttggg
    60121 tcgtcaatct ggtttctttc tgattttggc ttgccaaagg ccggatgcga aatatttagg
    60181 agacggaatc cgcgatcaat tcaactttcg cgtggctttg ggtcgtatga gtgaactcgg
    60241 atattccatg atgtttgggg aggtcgaaaa aaacttcttt atgaagcaca tcaaaggtcg
    60301 aggttatgtg gatacaggtg gcagtgtgat tagtgagttt tatacgccac ttgtaccaaa
    60361 agggtatgat ttcttagatt caattagtaa attagaaaag atgaatgatt gagtgatctt
    60421 caatactgac tttatacttc aagtaacgta taatactttt atatagtagg aagaaagggg
    60481 ataattaata tggaaagtaa tgattcttat ttagagtatg caaaagcaaa taaggataag
    60541 tttatttctt atattatcaa agggaaatcc cccgaagttg gacgagacgc agtttttatg
    60601 gcagggagtc ctggggctgg aaaatcagag gttgccattg gattagctga gaattatgat
    60661 aaccatgtga ttattgatgc ggattacttt cgcacccagt ttcctgatta taatggaaaa
    60721 aactctagtc tctttcaaaa agcatcttct tggttggtag agcaggcatt tagatatgtc
    60781 ttagatcatg gctattcttt tattctggat gcaacttttg caatattaag tgctgaaaaa
    60841 aatatctcgc gggcgttgaa aaaacatttt cgagtgacga ttttctatgt ttatcaagac
    60901 cctaaaatcg cttggaaatt tacacaagaa cgtgaaattg cagagggacg tcatgtgccg
    60961 aaaaaggcat ttattaacgc ttttttcaaa tcaagagaga acattgcaaa agtaaagagt
    61021 aaacatccag atgtattgct tcatatcata ataaaagatt atacgaataa tatttccgaa
    61081 gttcattatg ctacggataa tctagaatta tttttaccac tagggtatag taggaaagat
    61141 ttggaggttc aattacatga ctgagaaaga acaagtaacg aaaattgtaa agaaatacaa
    61201 taagagcatt gcggatttat cggaaaatgc tactgcaaaa gagttcaaaa cggtgattaa
    61261 atatgtagcc gatcaggcca atgaaaaaca acggaaatta gttggattaa ataaaaaata
    61321 gtaggacaaa ttaataatgt atgagccaag agcaaaatgt tcttggcttt tttctttgca
    61381 atgaatgagg taatgtatga gatttttaga tttattcgcc ggtattggtg gctttcgttt
    61441 aggtatggaa caggcgagcc atcattgtat cggtttttgt gaaattgata aatttgctag
    61501 acgtagttat aaagcaattc atgatacaag taaggaggtg gaaatgcatg acatcacaag
    61561 tgtatcagat gagtttattc aatccctcgg accagtggac atcctttgcg gcggatttcc
    61621 gtgccaagct ttttcaattg cgggaaagcg gcaaagattt tccgatactc gaggtacttt
    61681 attctttgaa atcgctcggt tcaccactct tctccgacct aagcttttat tccttgagaa
    61741 cgtccgagga ttgctcaatc acgaaggagg ggctacgttc gagacgatcc tccgaacgct
    61801 ggatggattg gggtatgacg tggagtggta ggtgcttaac tcaaaggcct acattcccca
    61861 aagccgggag cggatattcc ttatcggaca ttctcgagac gcatgtaccg aacaagtatt
    61921 tcctatcatt ggaccgtctt caacatctga tcaaaacatc agaaatttgg taaatatcaa
    61981 tccttccaat cgaggaatgg gtggacaagt ctatggttca gatggcgtag cgccaacctt
    62041 aacaggtgat gaaggaatca aaatcgcact gccagcaagg gatggaatct ctgtagcagg
    62101 actattaccg ggaaagtttg aacaaggtaa tcgagtttat gaagttactg gaaccgcccc
    62161 caccttgtca acgaaacaag gtggtacaaa aatcatgatt cgaaaaaatg aaacagaata
    62221 tcaagaggtg aagccagaag acagtgtgaa tctggctttt cctaattcca caagtcgccg
    62281 aggtcgtctg ggaaaacaga gtgttcatac cttactaaca ggagaccaac aagcgatcgt
    62341 cacggatcag tatcaaattc ggaagctaac acctagagag tgttggcgac ttcagggctt
    62401 tcccgattgg gcttttgatc gagattctca agtcaattca gatagtcagt tgtataagca
    62461 agccggaaac tctgtaacag ttccggtcat ttttgatatt gccagaagat taaaagagtt
    62521 ggatgtacat ggtttatgat gagttgattg gagaaattta ttgggtgatt ggaaagattc
    62581 agtcagaccc agaattagaa gaacaattgc gacggttaaa atttgatatt cgcaagaatg
    62641 gtgtcaaagt cgctggcgat ccatatttaa tgaatgagga gacggatgct cgaattgaaa
    62701 taaatcaagt aattgcagaa tttgagcgga ttgcggacca agcaaaagaa ccagatattc
    62761 gtcaatactt gttagaaatg aaagcagagt tggaagtaaa tggtattaca gatgagtaac
    62821 ctaaaccaac acaactgact gttaggcgct gaccgcggag gattcgcgaa gcagaaatcc
    62881 tccgtggtgc tgtgcctgtt catggacggc gttagccgac catgatgtct cacccccgta
    62941 tctaacaggg gggtacaaaa acacaaaaaa taagtaagca accattaaga atgcttgttg
    63001 tatcaaagat agtaagtaat ttgtataggt gttaactcat ttgaaaaagt taacaccttg
    63061 aatttggagg tgagaacttg gcacaacgga atttagatta tcggctatta aaagaccgac
    63121 gcaacgaata cggcgtttca caaaataaat tggctacggc ttgtggactt agtcggccgt
    63181 acttaaatca gatagaaaat ggtggcgtaa ccgcatctat aaaaaccatg aggaaaattt
    63241 ttgaccaact ggaaagcttt aatcccgatt tgcctttgac gttactgttt gactatgtaa
    63301 ggattcgctt tcccacaacg gatgcacgaa aaattattca agaaattctc catttgaaat
    63361 ttgagtatat gctccatgaa gattatgcct tttactccta tcaagaacag tatgtcatgg
    63421 gtgatattgt ggtgatgttg tctcatgaag aagataaagg tgtgctttta gaattaaagg
    63481 ggcgaggttg ccgacaattt gaaacttttt tactcgctca aaagcgtagc tggtacgact
    63541 ttttcgagga ttgtctaaag gccggtggcg tgatgaaacg cttggacttg gcaatcaatg
    63601 atcgagtggg gctattggat atacctgagc taacgaaaaa atgtcagaag gaagaatgta
    63661 tctccttgtt tcgtaccttt aaaagttatc gttccgggga acttttaaag gctgatgaaa
    63721 aggacggcat gggcaatacc ttatatatcg gcagtctcaa gagtgaggtt tatttctgtt
    63781 tgtatgaaaa agactatgaa caatatatca agttagggat tccattagac caaactgaga
    63841 cgaaaaatcg ttttgagatt cgactgaaaa atgaccgtgc ttttcatgcg attcaagatt
    63901 tgttaaaagg tcgtagcatt gagagcacca cgttttccat tatcaatcgt tacttgcgat
    63961 ttgcggataa agtagaaggt aaaaggcgaa ccaactggcc cttgaatgaa caatgggggc
    64021 gttttattgg acggaatcgg aaagagattc aattaacttc cgagccaaaa ccgtatacca
    64081 ttgaacgaac cttgaattgg ctaggccgac aagtcgcccc tacgtggaaa atggctaagg
    64141 agttggatcg attgaatcgg acaacctata tccaggatat ggtacagaat gcacgcttat
    64201 cagaccgaca taaaaagatt ttggagcaac aaagtatggc aattgaaaat ttgattatat
    64261 gaaaagagga atcgtcatgg gaattgtaaa agatattttt ttggtatttg gtggcagtat
    64321 gcttggtgtt actgtgatgt gcttgatgaa tgcaagtgca gcagcggatc gagcaatgga
    64381 aaagaaagga aagtgacaag atgaatttcg gacaaaattt
//
LOCUS       DAFLVO010000006        62467 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.006, whole genome shotgun sequence.
ACCESSION   DAFLVO010000006 DAFLVO010000000
VERSION     DAFLVO010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 62467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.006"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..434)
                     /locus_tag="L1U99_000405"
     CDS             complement(<1..434)
                     /locus_tag="L1U99_000405"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBN1210979.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQ"
     gene            680..1627
                     /locus_tag="L1U99_000406"
     CDS             680..1627
                     /locus_tag="L1U99_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBN1210980.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(1838..3910)
                     /locus_tag="L1U99_000407"
     CDS             complement(1838..3910)
                     /locus_tag="L1U99_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBN1210981.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(3843..4220)
                     /locus_tag="L1U99_000408"
     CDS             complement(3843..4220)
                     /locus_tag="L1U99_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HBN1210982.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(4349..4927)
                     /locus_tag="L1U99_000409"
     CDS             complement(4349..4927)
                     /locus_tag="L1U99_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1210983.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            5059..6351
                     /locus_tag="L1U99_000410"
     CDS             5059..6351
                     /locus_tag="L1U99_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBN1210984.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(6411..7529)
                     /locus_tag="L1U99_000411"
     CDS             complement(6411..7529)
                     /locus_tag="L1U99_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HBN1210985.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(7543..8964)
                     /gene="arcD"
                     /locus_tag="L1U99_000412"
     CDS             complement(7543..8964)
                     /gene="arcD"
                     /locus_tag="L1U99_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HBN1210986.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(9210..10331)
                     /gene="mnmA"
                     /locus_tag="L1U99_000413"
     CDS             complement(9210..10331)
                     /gene="mnmA"
                     /locus_tag="L1U99_000413"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBN1210987.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            10735..11334
                     /locus_tag="L1U99_000414"
     CDS             10735..11334
                     /locus_tag="L1U99_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HBN1210988.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(11472..12758)
                     /gene="efmA"
                     /locus_tag="L1U99_000415"
     CDS             complement(11472..12758)
                     /gene="efmA"
                     /locus_tag="L1U99_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HBN1210989.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(13029..13373)
                     /locus_tag="L1U99_000416"
     CDS             complement(13029..13373)
                     /locus_tag="L1U99_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HBN1210990.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(13510..14655)
                     /locus_tag="L1U99_000417"
     CDS             complement(13510..14655)
                     /locus_tag="L1U99_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBN1210991.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(14835..15809)
                     /locus_tag="L1U99_000418"
     CDS             complement(14835..15809)
                     /locus_tag="L1U99_000418"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBN1210992.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(15889..16764)
                     /locus_tag="L1U99_000419"
     CDS             complement(15889..16764)
                     /locus_tag="L1U99_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HBN1210993.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            16894..18801
                     /locus_tag="L1U99_000420"
     CDS             16894..18801
                     /locus_tag="L1U99_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HBN1210994.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(19342..22620)
                     /locus_tag="L1U99_000421"
     CDS             complement(19342..22620)
                     /locus_tag="L1U99_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HBN1210995.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(22891..23436)
                     /locus_tag="L1U99_000422"
     CDS             complement(22891..23436)
                     /locus_tag="L1U99_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBN1210996.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(23448..24140)
                     /locus_tag="L1U99_000423"
     CDS             complement(23448..24140)
                     /locus_tag="L1U99_000423"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBN1210997.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(24159..24443)
                     /locus_tag="L1U99_000424"
     CDS             complement(24159..24443)
                     /locus_tag="L1U99_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1210998.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(24456..25019)
                     /locus_tag="L1U99_000425"
     CDS             complement(24456..25019)
                     /locus_tag="L1U99_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBN1210999.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            25247..25909
                     /locus_tag="L1U99_000426"
     CDS             25247..25909
                     /locus_tag="L1U99_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBN1211000.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            26033..27229
                     /locus_tag="L1U99_000427"
     CDS             26033..27229
                     /locus_tag="L1U99_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBN1211001.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(27330..28706)
                     /locus_tag="L1U99_000428"
     CDS             complement(27330..28706)
                     /locus_tag="L1U99_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1211002.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(28743..29610)
                     /locus_tag="L1U99_000429"
                     /pseudo
     CDS             complement(28743..29610)
                     /locus_tag="L1U99_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
     gene            complement(29699..30724)
                     /locus_tag="L1U99_000430"
     CDS             complement(29699..30724)
                     /locus_tag="L1U99_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBN1211003.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(30742..31416)
                     /locus_tag="L1U99_000431"
     CDS             complement(30742..31416)
                     /locus_tag="L1U99_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1211004.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(31600..32493)
                     /locus_tag="L1U99_000432"
     CDS             complement(31600..32493)
                     /locus_tag="L1U99_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBN1211005.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(32567..34264)
                     /locus_tag="L1U99_000433"
     CDS             complement(32567..34264)
                     /locus_tag="L1U99_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBN1211006.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(34257..35570)
                     /locus_tag="L1U99_000434"
     CDS             complement(34257..35570)
                     /locus_tag="L1U99_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBN1211007.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(35570..39606)
                     /locus_tag="L1U99_000435"
                     /pseudo
     CDS             complement(35570..39606)
                     /locus_tag="L1U99_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
     gene            complement(39619..40077)
                     /locus_tag="L1U99_000436"
     CDS             complement(39619..40077)
                     /locus_tag="L1U99_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBN1211008.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(40375..40893)
                     /locus_tag="L1U99_000437"
     CDS             complement(40375..40893)
                     /locus_tag="L1U99_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBN1211009.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(40895..41512)
                     /locus_tag="L1U99_000438"
     CDS             complement(40895..41512)
                     /locus_tag="L1U99_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBN1211010.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(41509..42363)
                     /locus_tag="L1U99_000439"
     CDS             complement(41509..42363)
                     /locus_tag="L1U99_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1211011.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(42360..43271)
                     /locus_tag="L1U99_000440"
     CDS             complement(42360..43271)
                     /locus_tag="L1U99_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1211012.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(43312..44646)
                     /locus_tag="L1U99_000441"
     CDS             complement(43312..44646)
                     /locus_tag="L1U99_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1211013.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            44854..45684
                     /locus_tag="L1U99_000442"
     CDS             44854..45684
                     /locus_tag="L1U99_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBN1211014.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(45928..46210)
                     /locus_tag="L1U99_000443"
                     /pseudo
     CDS             complement(45928..46210)
                     /locus_tag="L1U99_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011066964.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(46368..46562)
                     /locus_tag="L1U99_000444"
     CDS             complement(46368..46562)
                     /locus_tag="L1U99_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211015.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(47067..47252)
                     /locus_tag="L1U99_000445"
     CDS             complement(47067..47252)
                     /locus_tag="L1U99_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211016.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(48102..48443)
                     /locus_tag="L1U99_000446"
     CDS             complement(48102..48443)
                     /locus_tag="L1U99_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBN1211017.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(48443..48673)
                     /locus_tag="L1U99_000447"
     CDS             complement(48443..48673)
                     /locus_tag="L1U99_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBN1211018.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            48960..49298
                     /locus_tag="L1U99_000448"
     CDS             48960..49298
                     /locus_tag="L1U99_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211019.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(49503..49742)
                     /locus_tag="L1U99_000449"
     CDS             complement(49503..49742)
                     /locus_tag="L1U99_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBN1211020.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(49718..50065)
                     /locus_tag="L1U99_000450"
     CDS             complement(49718..50065)
                     /locus_tag="L1U99_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBN1211021.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(50797..51378)
                     /locus_tag="L1U99_000451"
     CDS             complement(50797..51378)
                     /locus_tag="L1U99_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1211022.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(51561..52187)
                     /locus_tag="L1U99_000452"
     CDS             complement(51561..52187)
                     /locus_tag="L1U99_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBN1211023.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(52209..53540)
                     /locus_tag="L1U99_000453"
     CDS             complement(52209..53540)
                     /locus_tag="L1U99_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HBN1211024.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(53695..54096)
                     /locus_tag="L1U99_000454"
     CDS             complement(53695..54096)
                     /locus_tag="L1U99_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBN1211025.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(54182..54388)
                     /locus_tag="L1U99_000455"
     CDS             complement(54182..54388)
                     /locus_tag="L1U99_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211026.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(54483..55985)
                     /locus_tag="L1U99_000456"
     CDS             complement(54483..55985)
                     /locus_tag="L1U99_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBN1211027.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(56003..56458)
                     /gene="argR"
                     /locus_tag="L1U99_000457"
     CDS             complement(56003..56458)
                     /gene="argR"
                     /locus_tag="L1U99_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBN1211028.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(56556..57173)
                     /locus_tag="L1U99_000458"
     CDS             complement(56556..57173)
                     /locus_tag="L1U99_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBN1211029.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            57394..58767
                     /locus_tag="L1U99_000459"
     CDS             57394..58767
                     /locus_tag="L1U99_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1211030.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            58842..59954
                     /locus_tag="L1U99_000460"
     CDS             58842..59954
                     /locus_tag="L1U99_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBN1211031.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(60026..61663)
                     /locus_tag="L1U99_000461"
     CDS             complement(60026..61663)
                     /locus_tag="L1U99_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HBN1211032.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(61831..62439)
                     /locus_tag="L1U99_000462"
     CDS             complement(61831..62439)
                     /locus_tag="L1U99_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBN1211033.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
BASE COUNT        17830 a        13255 c        11046 g        20336 t
ORIGIN      
        1 aattggcgtt tgatttcaac cccatctatt gcgtttccca tatatcctgt cagttttcca
       61 ttttgcccga tcactcgatg acaaggaata acgattggca atggattggt tcgatttgcc
      121 tgcccaatcg ctcgcacagc tttcggacta tcaacagcaa cggctacttc tttatacgtt
      181 cggatttctc cataaggaat ggtcgacaaa gctttccaga cattttgctg aaaaggcgta
      241 cctctcttta tagataaagg aacatcaaat tcttttcttt ttcccgcaaa atattcttca
      301 aactgttctt gtgtgcgcgt taaaattcgc tgattcgctg attcgctttc tgaaattggc
      361 tgaaaagata cagcagtcaa tccggattca tctgcatcta accataaaaa gccgataggt
      421 gtgtgtattt tcattttgtt tgctcctagt caatagactg gaacttcctc ctttttctct
      481 atccaaaact acttgccaac taataaaaat tgttcttaaa agtttgataa accgaggaaa
      541 catggtaaac taaatacgtt agtttacaaa aagaatacct gttcttttac gtaaaatcaa
      601 attttaaagg tgttatttaa ggtttattaa attttgaatg taaaccatat ataaacatac
      661 gattgaaagg atagaaacga tgaaagtatc aattgttgtc ccatgtttta atgaagaaaa
      721 aactgttcct cttttttttg atgaggttga aaaattcaaa ggtgcccatg agttcgaata
      781 tttgtttatt gacgacggat caaaagacgg tacgttagca gcaatcaaga agctagcctc
      841 agcttatcct tatgtccgct ttgtctcatt ttccagaaat tttgggaaag aagcggctct
      901 gtacgctgga ttgcaagctt ctacaggaga tttagtgacc gtgatggatg ttgatctgca
      961 agatccgccc gaactgcttc ctgagatgat caaccggatc actacttctg atatcgattg
     1021 tgtcggcacc cggcgttcga ctcgtgaagg cgagcctgcg atacgcagtt tctttgcgaa
     1081 aaaattctac cagttgatca ataaaatcag cgatacagaa atggtcgatg gcgctcgtga
     1141 tttccgcttg atgactcgtc aaatggtgga tgccgtccta gaattaacag aatacaaccg
     1201 attttcaaaa ggattattta gctgggtcgg atttaaaaca gaatatattt cttatgaaaa
     1261 ccgcgaacgt gtggctggcg aaacatcttg gtccttctgg aaattattca actactcgat
     1321 tgatggtatc gtgaacttct cggatgcacc gttaacgatt gcttcattta tcggcgcttt
     1381 gtcttgtgtc ggttctggta ttgcaatttt gttcattatt ttgcgggcat tgttgtttgg
     1441 tgatcctaca tcaggatggc cttccatggt ctcgatcttc ctgttcattg gtggaatcca
     1501 attgttatgt cttggaatca tcgggaaata tattgggaaa atcttcttag aaacgaaaca
     1561 gcgtcctgtt tatatcataa gagaaacaga aaaagtgaag ccaaatgaat tgaagcctca
     1621 ccaataatat acgtcaaatg aagtaaacat ttttttaaat gaaaaaggac tgtgacaaaa
     1681 gtcttgtcac agtccttttt tccgaataaa tggtgttcca gaagtagctt cttcggaaat
     1741 aagccgaaat ttcacaaaaa tttgagaagc aattttcgta aattccttct tatttcttga
     1801 agctgaccac ttctatcaca acctctttca tatcttatta cttcttcatt gctgctttta
     1861 gtgctgctgc taatgggctt tcttctggtt cttctgcttg tgcatatttt ttcagcaagc
     1921 gtcgttcttc atgtttggtc attttcttct tctgctcttt tttatcaagc aatttttctg
     1981 tcgttccatc gtatttacaa cggaaataag caccgttttt accttcgatg atttccattt
     2041 tccggtgaca ttgcgggcat cgatgattag agacttttgg atcttttctt ctgcggtagt
     2101 tgcaatctga attggtgcag acatagattt tgccgtcacg tgtgtttttc tcgcgcagat
     2161 tggccccaca ttctgggcat ttcttttggg taatcgagaa atcttgatat tcttgtttgc
     2221 ttgatttgat ctcattcacc aagcgttttg tttctttttc gattccattc aagaaggttc
     2281 ctgcttgttt ctttcctgca gcaatagctt caaggtcttt ttcccagctt tctgtcaaat
     2341 ctggtgttac taaagaggga tttaccaata ctaataattg cttaccttta ggagatactt
     2401 gcagtccttg aggggtacgt tccatcagtt cagatttgat tagtttctcg ataatctctg
     2461 cacgcgtagc tggggttccc agactgtatt tttccatttg accaagcaag cttgcttctg
     2521 acaatggttt aggcggtgca gatagttctt ttttgatggc gaaatcggga ttgattctca
     2581 ttcctttttc ccatttgact gtttccgtct cagtttcagt ttcgcctttc catcctgctt
     2641 ggacgacacg attttgccga aaaatgaatc gttctttacc aaattcaacc gtaacttttg
     2701 tttggctgac tttatggggt tgagcaaaca gtcctaaaaa acgagagaca atcatttgat
     2761 agatttttcg ctcttcatta cttaattttt cataacgtgc tctgttttca gttggcaaaa
     2821 gtgcatggtg atcggtcact ttactgtctt ggaatacttt tgtctgttgg acgatggctc
     2881 cgtttttcaa atactgcttg acctcaggag caaagtcgct gactgcttgc aatcgttctt
     2941 tcatcgtact tttcatgtca tttgtcagat atttgctgtc tgtacgcgga taagtaacga
     3001 tcttatgggt ctcatacaaa ctttgtacaa gacttaatgt tttctttgca gaatagccat
     3061 agcgttgatt ggcttctctt tggatctctg ttaaatcata aggcaatggc gcagattccg
     3121 tttttaattt ttcttggact tctgtgacag ttcctttgct tgtactgatc aattgaacaa
     3181 gtttttgtgc ttcttcttgt gtttttaaag caaattgatt tttttgaagc attttggctt
     3241 gttcttttcc agcttgcaac gtgatcgtga aatacgtttg tggacggaac tgctcgattt
     3301 tcttttcttg gtctctcact aatgctagtg tcggtgtctg cacacggcct gctgataaat
     3361 tatccgcgta cttcacagtt aaggctctgg tcacattcaa tcctaccagc cagtccgctt
     3421 ttgcccgggc aagagcagat tcatacaatg catcatattc tttcgcaggt cttagttgct
     3481 tgaatccagt tttgattgct ttatctgttt gagaagagat ccataaccgc ttcactggtt
     3541 tattgaaatg cacatactct aagatccagc gagcaacaag ttccccttct cttccggcat
     3601 ctgtcgcaat gactgcttct gagacatctt ttcgctgagc cagctgcttg attgctttta
     3661 attgatgtcc tgttttagga agtggtttga ttcctagttt tttagggatc attggcaacg
     3721 tgtccatttg ccagctctgc cattccttat tcagatcttc cggcattttc aatcctaata
     3781 aatgaccaag ggcccaagta acgatcacct tgggtccttc ataataattt ttgtgctttt
     3841 gattagcacc aagcaccttg cttaggtctt tcgcaacgct tggtttttcc gctagaatta
     3901 gttgtttcat aaaattcctt tctgctttct actgtgatgg gctgatgatt tttcaacaac
     3961 gcaagtccct tgtattgctg taaatcatcg tcacactctt cacaccagcg ctcatctccg
     4021 tcattccaaa aggcgctgag aaagttactt tttgcattga tatattcata attttgatgg
     4081 atttcgttcc attgtttttc gtacgcttgt cgtgcttctt cgaaagactc gaatgtttct
     4141 tcttcttcaa tatcttcttc ccagtcttca aaaaaccacc aaggctcatt gtccccgaac
     4201 atggtaatta cttgatacat actcgtgctc cttctttcag cttttctaga ctcatcttag
     4261 tcacttttca agaaagttgc aagaattttc tcttataaaa gggtcattta atgaacatct
     4321 taaaattgtt acaaatgaat ctgattgttt aaggcaaagt agcgataaag ttattgatca
     4381 tccaaaaata gctgtcttct ggatcgattg ttggttcttt tgtaaagtat cctaaaaaac
     4441 gtaaggaaag ataaccgtgg atcatactac gaagttccct gcttcgatga actttttctt
     4501 ctttcgttaa ttgaaaagcc tcaaatatct gcaaaatgat ctgattcgtt tcatggattc
     4561 catctaataa aacagcttca ttggtatgcg gtacactgat cagtaactca tacactgctt
     4621 gatttgaaaa agcaaaggat cgataagttt ctgcatagat ctgcagtgct tcctgaccac
     4681 tttttcccac aagagcccgt cgcagctggt cattaagttc ctgcagaagt ttcgctgtta
     4741 gcgctgtttt gacatcacga atatttttga aatggttata cagcgaggga gccttgatat
     4801 ccaagcgttt ggctaaatgc tgaaaggtta tttgctgaac atccatctct tctgctagtt
     4861 ctcgaaagca gtcgatgatt ttctcttgag acagatttct ttttttcatt tccatgtttc
     4921 ctctcataaa ataaatcctt cactctttca gtttaccacg aaaaagaaag agaaaaaaga
     4981 gactttcatt gataaactac atattgtagt ttataataaa gagctgtaga tgaaaatttt
     5041 cagaaagaag gagtctaatt ggctgcaaga ataaaggaaa aattatttag gaaaagagaa
     5101 acttgggaac aaaacttgtt tgtcttatgg tttggaacat ttatggctgg tatcggattt
     5161 agtttagtca tgccttttat gtcactttac atagatacgt taggtaatta tagtacgtca
     5221 caattgaact tttggagcgg attgactttt tcatctactt tcttggtgac tacgcttatc
     5281 tctccttggt ggggaaaatt agccgaccaa aaaggaagaa aattgatgct gttgcgtgct
     5341 tcattaggaa tggcaatcgt catttctttg atgggttgcg tgactagtgt gtatcaatta
     5401 gtcgcattgc gtctgcttca agggattttt tctggttata tcagtaatgc cactgccctt
     5461 gtcgcaactg ggacgccaaa agaaaaaagt ggtcaagttc ttggaacctt agcaactggt
     5521 tctgttacag gaacattact tggaccgctt cttggcggga tctctgcttc agcgtttggc
     5581 tatcgcccta cctttttcat tacagggatc atcttatttt tcgtcttctt gttgagtctg
     5641 tttttcgtcc atgaaaaatt tgtcccagtg aaaaaagaaa acatggtttc tgccaaacag
     5701 attttcaaag acttgaaata tccacacgtc gtcatcggta tgttcgtcac aacgatgatc
     5761 atccaagcat ccaacaattc cattagtcca atcatcagtc tgtacattcg ccaattgctg
     5821 catggacatg ggaatgttac gttgatcagc ggaatcattg cttcgatacc tgggattgcc
     5881 actttgatag ccgctccaag atttggtcgc ttaggtgaca agattgggag tgaaagaata
     5941 cttgcgattg gtttgggttt tgcgattctg gtttatatcc caatggcatt cgtcacgaat
     6001 gtttggcaat tagctgcctt acgttttttg attggtatct ctgatgcttg tctgctccct
     6061 gctgtccaag cattgatcac aaaatattcg cctcatcaag ctgctggacg gatcttcagt
     6121 tataaccaat ctttccaagc aactggtaac gtagtagggc ctatgatcgg ctccagtgtt
     6181 tccagtgcat ttggttatcg cggcgtcttt ctttcgactt ctcttcttgt tttggtcaac
     6241 ttcttgcttg tacgacacaa tacacaagag atccatcagc aagaaactgc agaagaaaaa
     6301 gcttcaggag tctccatagc ttcagggcac tctccttctc atagacaata agcgtaaatg
     6361 aaaaacactg cttgaacagt tgtcacagac tgtccttgca gtgtttttgt ttaggcctgt
     6421 tttttcaaga actcagataa gaggaataat cccttttcca aggtttcttt tttacaacag
     6481 taacctagtc gggcatgctt cggtaaatca aaggcacttc ctggtactaa tagtactcct
     6541 gtttcttcta ataaattgat acaaaatgtc tggtcatctt cttcgatggc taatttaatg
     6601 aaagaagtag agacgtaatt gggagcgaca agttcaactt tcggttcatt ggctacccat
     6661 tgttttaaaa tcacaaggtt ctctgtaatg atctttttgt ttcgcgccaa tattttttct
     6721 ttattcttca atgcatgtac agcaagatca tctgacagga ctccgccgca aatcatcgtg
     6781 tagtctcgat actttcgaaa aacttctgcc aactcaggtc cagtagctgt ccagccaata
     6841 cgaatacctg gaatggagta ggttttggat agggaattgg ttgctatacc tttttcatag
     6901 acatctacga tcgacaagaa ttcaccttta tccgttaaag gcgcatatac ttcatctatc
     6961 aatacatatg catctactgt acgagcaatt tctgcgattt tttctaaagt tttccgatct
     7021 agcaatgtgc ctgtaggatt gtttgcacta ttcaaacaga tgatttttgt ttcaggtttg
     7081 actaaggctt ctagctgttc taaatcaaac tgccaatctt cttcttcctt caaatgaaca
     7141 aagtcaacag cggcacctaa agatttgggg atgtcatata attgctgata agtaggaagc
     7201 atcgaaacaa catggtctcc tgcttccact aacgcgtata gagctaaaag attagcacca
     7261 gtcgctccat tcgtttgtaa gatgttttcc ggatcgacgg tttgataaag agaagcgact
     7321 tcttgtttga aaacatctga tccttcgatc cagccatagt ccaatggttc gtttttgcgt
     7381 ttttcgaaaa atttacttac gctagtccca tctaagccaa cgagttcgtc taatgtcaat
     7441 gcttcgatcg agctttgtgc aatatcatat accgctttct tttcccattt atttagccat
     7501 tcttctacac cgaaatttgc gattttcatg tttctttccc ccttatatct tgatccagcc
     7561 tacagcaagc aacccgattg aaagcagtgc ggccacacaa atcagcccaa tcattacttt
     7621 ttcttttccc gtaatttgat gtttggtttc acgacaagcg atccagtaga agcaaaaacc
     7681 aggaagatag gcaatactac ataaaaggac ataagaaaat cctgctaaaa tgatgcccat
     7741 caattcaaaa actacagcaa tcccaccgat cactacttgt tttttgattc cttcttttaa
     7801 agaaaactgg acttgataga tcccgacaag tagataacaa atcaaaattg ccgctgtaca
     7861 taaagaatag gcaaattgat aggcataatc agtaactaag aaagtcaata agaatagatt
     7921 agtcaagatt gcagtaacaa ctaacgaata agttggggca ttttttttat tcgtttttcc
     7981 ccaacctttc ggcaacagac cgtctcgagc catcaacatc gttgtttctg ctgggagcat
     8041 cgtccaagac aaccaagaac caatgatcga aataatcaag ccgatattga tcagcgctgc
     8101 tccccaattt cccacgattc cttttaaaat atttgccata gcaggttgtg aaatagttgc
     8161 taactcttct tgagataaga cgccgtatgg caagatcgaa gcaaggatat agataaacaa
     8221 taaacaaagc agaccaatga tcgatgcttg ctgggcttct gaacgtttct tcgcgcggtt
     8281 ggctaaaaca cttgcgcctt cgatccctac aaagacccac atcataacca tcaaacaacc
     8341 tttaatctgc aaccagatcg ttccttgctg ccctgttcca ttcactagat tatcagatac
     8401 gttaccccaa aaatcagcag tgaatatatt cactttaaat gcgataaata caaatattaa
     8461 aaataggaat aatggcacta atttacagat cgtcacgatt gtattgatga cgctcgctcc
     8521 ttcaactcca ttgtttacta ataaagtcag accccaaata aaaatacttg caaataaaat
     8581 agaaggaaca ttttgtccac ctttgaatat cgggaaaaat tctcccatgg cgctcatcag
     8641 catcgttgca aaagcaacat ttcccagcca cgcagacaac cagtaacccc aaccactgat
     8701 gaagccacct aatttaccaa atgaagcttc cgcgtaaccg aaaataccac catctagatc
     8761 tggacgcttt tctcctaaat gattcagcga taataccaaa gctaaaatac caatcccaac
     8821 gattatccat gaaaggatcg ctggccctgg agctgcagaa ctagccagat cacttgtgat
     8881 cccaaacaca ccgcttccga ttgacgaact gacaaccaga gcaaccagtc cccatttgct
     8941 aatacccgtc gatttctttt ccatttccat caccctcact tataaaattg aacaaatcac
     9001 ttgcaaaaga ttcccttcta ttttgcaact gctcttgctt aacaaaaagc aactttattc
     9061 atattattgg atattatgaa ctttttacac aagtatttca agtataaaat gaataaaaat
     9121 taattttatt gcaaaaaaac agctatgcta tccaaaagaa aaggtgtttc ttttgttagc
     9181 catagctgtt ttgattcatt taatatcgct taaacgtatt gtaaaacttt tgtttcttga
     9241 tatgcgtggt cgatcaaacc accacccaga cattccattc catcataaaa tacaactgct
     9301 tgtccaggag tgattgcacg tacaggttcg tcgaatacga cttctgcacg attatcatcc
     9361 aataagcgaa ctgtcacagg aacgtcttgc tgacgataac ggaatttcgc tgtacacttg
     9421 aattcttttg gcattggttc attcgtcgta aagtggattt cacttgcatc caagcttgtg
     9481 gcatacaatg caggatgatg gaacccttgc cccacatata atgtgtttgt cgctagatct
     9541 tttcctacaa caaaccaggg ttcttgcgaa tctcctccgc caccgatccc tagtccttga
     9601 cgttgaccaa tcgtataata catcaagcca gcatgttgtc ctttgacttc accatcaaga
     9661 gtgaccatat ttcctttttt tgctggcaga tagttgctca aaaattgttt gaagttcttt
     9721 tcaccaataa agcagattcc cgttgaatct tttttcttag cagtcgcaag gcctgcgcgt
     9781 tcagcaattg cccgtacttc tgatttttcc atgccgccta gagggaacat cgtttttgaa
     9841 agctgttctt gtgataattg gctaaggaag taagtttgat ctttattatt gtctactcca
     9901 cgaagcatgt ggaccacgcc gttttcatcg cgagtgactt gcgcataatg tccagtagct
     9961 acataatcgg cgccaagatc cattgcataa tccaagaatg ctttgaattt gatttctttg
    10021 ttgcacatca cgtctgggtt aggtgtacgt cctgcgcggt attcggctag gaaatattca
    10081 aatacacgat cccaatattc tttttcaaaa ttcacagagt aataaggaat cccgatttga
    10141 gcagctactt tcgctacatc cttataatct tccgtggccg tgcatacacc gttttcgtcc
    10201 gtgtcatccc aatttttcat gaatattccg atcacgtcgt atccttgttc ctttaacaaa
    10261 agtgctgtta cagatgagtc gacaccgccg ctcatcccta cgacaacgcg tgttttgctg
    10321 ttgtctgtca tgatatcacc atcatttcaa ttagattctg aaacatctac gagttgaagg
    10381 tcgcaacttt tcagtatttt acattatacg tcatatttct gaaaatttca tcccttaatt
    10441 atcaagtcgt aaaaatactg ttctactgga cctattcagt acacaaacat gatagtcaac
    10501 caaaaaatca ctcatctttt gagcattcga tataaaaaat tggcatactc ataaaaaggg
    10561 ccagcctttc ggcaataagg aataatttta taaattgtga aaaactattt ttcaaaattg
    10621 cttcttatcg cttaaagctg cacgtctcat ttacaacctt ttctttttag atgttatgag
    10681 ttgctcagat aagtgatttt gtttactcta agaaaaaagg gaggcaaaag atacatgaat
    10741 tactttatca gtgatatgca ctttttccat gaacgcttat taggaaaaaa cgactttgct
    10801 ccgcggctct ttgcaaatgt ggatgaaatg aaccaacagt tgatcactag ctggaatgca
    10861 gtaataaaag aaaccgacca tgtttatcat ctaggcgacc ttgctatgca tccgcaatat
    10921 gaaaaagcaa atgcagaaat tttggaactg gtcactcaac tgcaaggaac aatccacttg
    10981 atcaaaggga accatgacag tcgcgctttt ttccgttatt tagaaaaaaa tgatcctagg
    11041 cttactgacg gaagtcccaa attttatttt tatgatgtag gtgccatcgt taaattcgac
    11101 catcaacaat attacttgac tcattatccg atgttgctcg ggcctaacga cactatccgc
    11161 aatcttcatg gacatatcca tcattacagc gtacctatcg agaacgatgt caatgtaggc
    11221 gtagacgcac cggaaagaga actcttaaag gaaaaactac catttggcac tccgttatct
    11281 gagcaacaaa tcaaagaaat ctatgaagca aagaggaagt acgataggtc gtgaaaaaac
    11341 tgccctatat caagtattaa acaaataaag ataattactc atatttttca tttgagtagg
    11401 cttattgcca caggaacatt aggatcagaa atggagttgt aacaagactt ctgtcacaac
    11461 tccattccat actattcgtc tttttgctca tggtgttctt ttaccagttt tttctgtaat
    11521 tctttatcat aatttcgggc agctgacgtt aaaaataaaa cgattccgca taataaaatc
    11581 ccgattccgg aaaacaagaa cattttttct acccctaaac gatcagctaa tggtcctgca
    11641 aataataatc caattggacc tgccaggttc atcaaagagt tgaagttccc taagacacga
    11701 cctaaaacat tcgattcata actctgctgg atcattgcca tcagcagtgt attgaaatat
    11761 ggcgttgcac aacctgctcc tgcattcaag ataagaaagt acaagaaccc ttgactatcg
    11821 tttggaacca atccgcttgc accgatcgtc aggcccataa tgatgtaggc tataataata
    11881 ggtttcattc ggtctttcca tgttcctata aaactgatca gtgcaccgcc taagagcatt
    11941 ccgactgcgt agactacttc cactgctccc gcctgtccaa cggaaccacc aaagtaatct
    12001 agcgtcatca atggatacag actgattgct ggcatgaaca acagcatcac aaatgcacca
    12061 ttgatcgtta tgtaccataa ccctttatta tccatcaatt gctgcagccc aaattttgca
    12121 tctttaaaaa tagtaagcgg aacttccaat atttcaggag aaacttttgg gatcttcaca
    12181 aaaatcaata agccgacacc aaaaactgcc cccaatacat ctaataaaat aaggtaattg
    12241 acaggaacga ctgaaaacaa agccgcacct agagctggcg caatgatgaa attcgctgat
    12301 tggaccattc ctaactgtcc attcgtcctt gttatgtgag aagatggaac gattgtcggc
    12361 ataatcgact ggatcgttgg catttggaat gtttgtgcga ccgaacgcat aaacaaagac
    12421 acaaaaacta gccaaatcgg gaaggattct gaaatcgttc cgactactgc taaaataagc
    12481 gcgaaaatcg ctacaataat atccgtgaca atcaaaagag cttttttatc ccagcgatcc
    12541 actagcggtc ctacaaatgg gcttagtaaa accatgggaa tcattcctag taaagtagca
    12601 aaactcaaaa ttgtcgccga accggtttct cttgtcaaat accagatgat cgcatattgg
    12661 acgaccatac tagtgattcc tgacaaaaac tgtcccgata aaaagaacaa ataatttctc
    12721 ttccaattcg ttaaaacgac cgactgttca ttttccataa acatccctct tttctttttc
    12781 attttgtata gcgtttgcac aacaatcatt atacgggatt cttttttcaa aaaatacctt
    12841 tttccctaaa taacaatcgt ttcaatttaa atttctttac ttagaaacaa taaatcagca
    12901 aaatattaaa aataacaaca tgtgttaaat ttaaaaataa aaaagacaac taatttgcgt
    12961 cgtccttaca aagttagtca tctaacaata ggccgtttca aaactagttg tctttttata
    13021 tccacagatc attcgacttt ttcgaataac ccacggctaa tcatcccatc catcagaaaa
    13081 taaaatttat cttggctcat tttctgtttt ggatctttga aaatattgac tgctttcaat
    13141 ccatttgctg tagtgatcga cattttcaat gtttgaatat cttttgatac agtgattttt
    13201 aatttgaatc cttctttgct ttgcggcgtg gcatctaatg gtcggatcaa ttgataattg
    13261 cctccgtttg tttctgtaaa tccattatcg cgcaatgtat atctttttgc atcaggatgc
    13321 aaacgatagc taattggtgc gcccagtacc gttgctgttg tttcaaatgc catgattttc
    13381 acctcgataa aattagtttc tctttattat aaaagtttat cctgattttt actaggtttt
    13441 tcagttaagt tccctaaaaa atgaaggcgt tctctcagac atctgttcat ataagaatga
    13501 cttcactagt tattttttga cagcacgaac taattgatca aggaaatact ggatgtcgtc
    13561 ttcggtattt cccaaaccaa agctgatacg gatggattct tttagtatcg gtgtatcttc
    13621 tccatacatt gcttctaata cgtgtgaagg ctcgatattt cctgctgtac aagctgaacc
    13681 agtagaaata gcgaccccat taagatcaag cttcatcagt agcaaatcat ttgcttcgcc
    13741 aattaagcga agattcaaca catgagggag tttattcgtt aaatcaccat ttacttgata
    13801 agggatttcg tttgcttcta atgtatcaag aatcaattgc tggaatcctt tatatttgtt
    13861 gttacgtgct tcacgttctt caggtgacag cagttcaact gcttttgcca taccccagat
    13921 ccctgctaaa ttttctgtac ctgcacgccg cttttcttcc tgctccccgc ctaaaagcaa
    13981 tgcagggata tttactccgt ctcgtttata taagaaaccg acgccttttg gcccattgat
    14041 tttatgagca gagatactta ataaatcgat tcctaattct tctggatgga tcgtttggtt
    14101 tccgtacgct tgtaccgcat ctgtatggaa ataagctgga tgatccgcta aaagttcacc
    14161 gatttctttg attggcatca aatttccgat ttcattgttc ccgtacatca cagagaccaa
    14221 gatcgtatct tctcgtaacg cttttttgac ctcttcgatc gacagattcc ctttttcatc
    14281 tacaggcaga tatgtaacgt caaacccctt tgtctctaaa tatttcatgg tattaagaac
    14341 agcaggatgt tcgatagctg tagtgattag atgtctgcct tctttttgac gcgagaacgc
    14401 tgtttctaag atagctgtat tatccccttc tgttccccca ctgttaaaga tgatctcgtg
    14461 aggttttgct tgcagactgt ctgcaatgat ttgtcttgct gtttccaatt tttcatgcgc
    14521 gtggcgacca aatccatgta tgcttgaagg atttccaaac gtgtcttgca tgattgccgt
    14581 catcgcttca attacttgtg gatgcatggg ggtagttgcc gcatgatcca gataaatagt
    14641 tttcacttca ttcatccctt ccaaattatt gctaggcaca ttctagcata aaatagcgaa
    14701 caaaccaaag aagagctcat ttttgtctag aggacgtttc atgggcatag aaaaaaggag
    14761 ctgtgacaaa agtcttgtcg cagctccttg aagctgctca cttctgtcac aacttctttc
    14821 cctctttttt ttgtttattc gaattctttt tcttccagac ggaataacgg actcatcggt
    14881 gtattttcat ggatgcgttt gaccgcttca cccattaatt ctgaacatgt aacgattgtt
    14941 aagttttctg gatgacgatt ttcttctgtg aaaacagaat cagtgataca aatatctttg
    15001 attggtgcat tgtctaaaat acttttcgca tgatcggaca ataatccatg tgacgcacag
    15061 gcatatactt cttttgcgcc gttttctttt aatacatttg ctgctcgtgc aagcgttgct
    15121 cctgtgttca agatatcatc taccatgata catgtctttc cttgaacatc accgatcaca
    15181 taaccaccct cagttgaagc atcatctgca tgatctacga tggctaatgt gctgttcaaa
    15241 tattctgaaa gactacgtgc acgctgaaca ccgctgtttt ttggcgaaac aactacgatg
    15301 tcatctcccg tcagacctaa ttgacggtaa taatgagcaa acaacggcat cgtaaataaa
    15361 ttatctacag gaatatcaaa gaatccttgt acttgaaccg tgtgcagatc taaagtcagt
    15421 actcgagttg cccctgcttc ttcgatcaag ttagcgatca atttcgcagt gatcggttca
    15481 tgaggtttcg ccgtgcggtc ttgcctagca tacccatagt aaggcaatac gacattgatc
    15541 gttttcgcac ttgctcgctt cattgcatcg atcatgatca gtagttccat atagtaatca
    15601 ttgacaggtg cattcgttga ttgaacgata tacacatgat cccctcgaat actttcttcg
    15661 atattgatgg aaatctcgcc atcactaaat tgcttcacga cgcttttacc taattctgtt
    15721 ccgaacactt tcgcgatttt ttcagctaat ggacggttgc cattcaaact aaaaatcttc
    15781 aacgtgtcat cctgatactt attactcatg tagtcctccc caaaacttct ctattcttcg
    15841 atagtttaac atatttttcc aagattttct gttaatttca gcaaattctt aaggaagtga
    15901 aactgttccg ttactccaac tggcaggaat gactttatga taatcgcccc agttgtcgtg
    15961 tactttgtaa taacgttctc ctgtttcagt ttcaaaataa gcgtacgctg tcacccaatg
    16021 attgccatat gtactgccaa gtactttcaa aataccaatc atcacaggtt tgccttcacg
    16081 tatacgtttt gtagctcgct gccatgaacc tagaagagtt gctcgtgcac gctcatgatt
    16141 gccattcttc tttaaaaaac tagaaatccc tgtactaacc tgaaaaggaa tcgtaggaag
    16201 tcctagtggt tggatctggc tacgcaatgc cttcgtcaaa accaacgaat cagccgtatt
    16261 tttcttgcga atctcatttg gaagcatcca ccccttacga tagtcttgat aataggcaag
    16321 gagaactgct gccgcgtaag taccacaaag atagcctgag ggggtagccc atttcttata
    16381 cctcaaaaaa cgttcttctg gcaatcccac ccagcaattt gcgagttcct ttcctgacct
    16441 tttttcttcg atcaaaacgg gaatatcttc ttttctgttg atccatctag ataactcgat
    16501 tggctcttca ttgatcagct tccatttttt acaagaaaga ccctcttgat aagtatattt
    16561 tgctggagaa tattctaccg gatgtcctga ttgatcgata atcacataac tttgatcttc
    16621 aaaaaccaga gctaaaaaaa gcaatttact ttttcttgac tgcagctgct gagtgctggc
    16681 taatttttta atttttttat ctactttgaa atataaaggt ttatccacta cttgattcag
    16741 ttgggatcgc ctcctttttt tcattataag tgaaggattg aaaaaaacaa atcagtttga
    16801 ttgttcgaat tttcaatttt ttatgttcta tttgttaatt ccttcatttt gtaagataat
    16861 gggcacacga aacaaaaaag gagcgatcga tgaatgaaca aagaacgatt gaaacaagat
    16921 ttctatgaag cagtcaatga agaatggcaa aaaacagcaa aaatccctgc agataaacca
    16981 gctacaggcg gtttccaaga tttagttgac gggatcgacc aacttttgat gggagaaaca
    17041 gacgatctgc ttgcccatcc agaaaaagtg tcttcagaaa aaatgaaaca tttccttgca
    17101 tattatcaac tggcaaacga ttatgaccga agaaatgagt tgcatgctca accgcttcaa
    17161 cctataatcg aaaaagttga atcattgcag tctttcgacg aattgaataa gcaatttcca
    17221 gaatggctgt tggatacatt accattgcca tttaatctgg atgtagatgc agatatgaag
    17281 aatgcgcaaa cgaacgcctt ctttgcttat ccgccttctt tattccttcc agataagacg
    17341 tattatgcat cagaccatcc caacggtgca caactaatag gcgttttctt tgatatggct
    17401 gttcagttat tagagcttgc cggcaaagaa aaaagtcagg cagaagcaat cacggaacaa
    17461 gcagtgcaat ttgataaatt gattgctcct catgtaaaaa gtgcagaaga aaacgcagat
    17521 tacagcaaaa tgtataatcc gcaatctttt gatacattta ttaaatacac agataaactg
    17581 gacttgaaaa aacttgtcac gggtttgatt gggacaactc cagataaagt gatcgtaact
    17641 gatccagtgt acttcgatca tttgaatgac atcctgacag aagctcattt tccgttattc
    17701 aaaagctgga tgatcattaa aacagtacgt tctcttagtg gttatctatc agaagaattc
    17761 cgccaagtca gcggaatcta ttctcgcgta ttgtctggaa cagacgaagc aatgcctcag
    17821 aaaaaagcag cgtattacct tgcctctgga caattcgatc aagtagttgg cgattactac
    17881 ggaaaaaaat attttggcga agctgctaaa aaagacgtag aacaaatggt gaaaaaaatg
    17941 atcgccgttt ataaaaaacg tctagaagaa aatgactggc ttggggatgc aacaaaagaa
    18001 aaagccgtca taaaattaaa taacttaggt atccaagtag gctaccccga taagatccca
    18061 gcattattcg accagttcaa aacagtacct gcagatcagg gtggtacttt gctttcaaat
    18121 actcttgttt tcagcaaact cacattaaaa gatcgtttca gcaaatggaa caaaccagtg
    18181 gatcgttcag aatgggaaat gagtgctgac acggtcaatg cttattatca tccatttcgg
    18241 aatgtgatcg tctttccggc agcgatcctt caagcaccat tttacagtct agaacaatca
    18301 agctctgcta attatggtgg aatcggagct gttatcgctc atgagatttc ccatgcattt
    18361 gataataacg gcgctttatt tgacgaatat ggcaacttga acaactggtg gacagaagaa
    18421 gatcttacac aatttcaaaa caaagcacaa gcaatgatcg aagaattcga tggtctgcct
    18481 tttgctgacg gaaaagtaaa cggaaaatta accgtttcgg aaaatattgc tgatgcaggc
    18541 ggtctaagct gtgcattgga agcagcaaaa acggaatcag atctttctat cgaggaattc
    18601 tttgtcaatt gggcaacgat ttggcgtaca aaagcaaaaa aagaatacca acaactttta
    18661 ctgcaaatcg atgtccatgc ccctgctaaa ctccgagcaa acgtgcaacc aaaaaacctt
    18721 gacgaattct atgaaacatt tggtatcacg gaacaagacg ctatgtatct agcgccagaa
    18781 aaaagagtgc gaatctggta agaggttgtg ccagaagtgg tcagcttcaa gaaataagaa
    18841 ggaatttggg aaaatcgctt ctcaaatttt tgtgacattt cggcttattt ttcgaagaag
    18901 ttacttctgg aataccatgt attagaggtt gtgaaaaagc tgcttagttt caagtagtaa
    18961 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttgactta ctaccgagaa
    19021 actggctttt gaacaccgtt tatcgagagg ttgtgaaatc agcgtcctga cctgagtatt
    19081 agagaaaaaa acggaaaaat agttcctcat attttgccgt ttgttgagct aataccgagg
    19141 gtcagctgat tgaacaccgt ttagtggaga gattgtgaaa aagctgtcct gcatcaagta
    19201 ataagaacag ccaatcaaaa gcagcaagga gaacctcatc tataaaaaga tagaaggaag
    19261 tgagacatct attggtctca tttccttcta tttttacttt cctcagtcaa ttgttttaca
    19321 tcataaaagg agaaattcca cttatttttt tcgctgtttc atgacataaa caactacacc
    19381 gattaacaaa attcctccag ctaatgctag caacgggtta ttaaattctc ccgtttttgg
    19441 gagtccttga gtgccatttt tttcactttc ttttgctgtc ctatccggat gagaaggttt
    19501 tccatttggt tttccatttg gtgattcatt tcctggattt tctctttctg gtttgtcatt
    19561 tcccgggggc acatcggcag tttctcgcac agtgatcgct ttttgctggg taacagattc
    19621 tgtatgagca gaccattttt ccccatcaaa tatttccgaa cgataagtga cttctagcgt
    19681 atattctcct tttgaaggtg ctgaaaaaat agcggtatga ttagaaaatt gagcacttga
    19741 ctgtgtttca acgatttgga tcttttctgg gaaataacgc atatcttcaa agacaggcgt
    19801 tccttgattt ggtgtgaaag ttgacacaaa aactgtaaaa ggcttcagtt caatgatatt
    19861 tccttctgca ttctccgcca caccatttgc ttcttgtata ataatcggat tattttgttc
    19921 atttggtttt gtctgatttg gttcttgtac gattgcatac tctggatatt ccgaagacgg
    19981 tgaggtttct ccgtcaaaaa tagcacctac agataatgga agaccatcca ctctttcctt
    20041 ttctgtttga cgattccccg gtttaatctg catcagtcca tgaacatgga tacttccatt
    20101 ttcatagcgc gtaacaggct gctgaccttc tttcgaacat gtatttagag actcgatcca
    20161 atcttttgat atggtatgtc caagagtatt ttctgattgt ttctctcgtt cattccaata
    20221 gtagttcaac gagtggtaga tttgatcttc gttttgattc aatgggcgga tctgctctct
    20281 catctcaaga ttctctgttc ggaaagataa gataccagaa gcatggtagt ctgtgtttcc
    20341 tgctgaagag gtataaagag ccacattata tgaaccgtta ttaaaacttg tactgctatt
    20401 gacgataata tctgttccgc tattggaatc gattcctttc gcaagatttt cgaaagacaa
    20461 actattgatc aattcatgag ggcccgttaa agaagaaccg cccattttga atccattacc
    20521 gttaccttct ccctcaattc ctggtaccca gccgtttcga taagcaactg agtttttgat
    20581 gattactttt ccgatcgaac ctgtttcatt tttagcaaaa aggtcccaac cgtcatctgc
    20641 attatgatac gcgatacaac cgtcaaatac atttccttct cctattgtca gtttggccgc
    20701 aaatccatcg gcatcttcaa atcctggatc ggcattttca aaagatgtac agttcttgac
    20761 taagttatgc gcgggccatg cttcgaaagg atcatttgag ctaccgctga tttggattcc
    20821 tgtatttcca ttccgataag catgaatctc ttcgatcaaa ttatgatttc cagaaatctg
    20881 taatcctttt tgcatagctg cactatttgt aatgtcaaac cctcgtaaac cccagtagtg
    20941 actgaacagt gtcatcccat ttccagttcc tttaaaatca agtacaggac gcttgttttc
    21001 tggatttttc tctgcaatca actgaatcgg gttttctctt gtcccgttaa cgccttttgg
    21061 aatcgtcaat cctctttcga aggaataagt tccaggcgcc atgacgattg tctgcccagc
    21121 atatgcgtat ctcaatgctt gtgtcagaga taatggattt tgtctgcttc cgtttcctgc
    21181 atctgaccct tctggtgtta cataaactgt cgaatattta ggtttacggt agtccactgt
    21241 atgaagaatc tcttttgttt cataactagt catctctacg tattcttctg gcggatagtt
    21301 tttatctggc gtaaaactga aagtaaattc gttcgttcct tccatcagtt ttgtctgata
    21361 atcaaattcc cgattcgcag tgatagccaa gttttttgcg ttcttaagca cctctcctgt
    21421 tgctttattt ttaattgtca ataatccgtc agcatttgct ctaaaggaca tagtatgatc
    21481 ttggtttcct gaatgattac tagaggtcac agtgtaaatc ggatcaatca agcgagtagg
    21541 tctttcttgc ccaggaggat ctgtcgcagg atctgagtaa gcaacttcga ttccttctac
    21601 cttgatcgtc atattccttg ctgcagcaaa tcctgcataa ataaccgatt catctgaagc
    21661 gtataatttt tcccagtcat acatgatgtc agaagccatt tcttctcctg tttcaggatc
    21721 gtaataatat gcctctaaac cagtattcgt ttttttcatc tctacgtcca gtttagtaat
    21781 cgagttcgtg gccggaaaca gattcccatg accgtttccg aatatattat aagaacctgt
    21841 ttctttttcc aagaaccctg ctgaagtctc taaaggtgtt gtttccactg agacactccc
    21901 aggagctggc gcagcttgcg gatcttcaga tgatattcct gtgattgccc gtgtccccaa
    21961 tccaagtcgc atcgtatatt tgctgccgct cgtgttgacc acttcttgtc tatccgagtc
    22021 ccagacatat tcgatccgac tgcctagtat ggcaaatgaa tttgaataaa atgcctgccc
    22081 aaacaaatga ttttttggta ctgcgtctct taccattaaa gcaaatcctt cttgggcatt
    22141 cgtataggtc caagattcta tttcgatcgt cgcccgcatc ctaaagttga tgtctttggg
    22201 gattgcttga taataatagg tcattccatc tgatccgctt gactggaatt ttccgccgtt
    22261 attcgtggaa gagagccgca cgccgtcttc taatggttca atggcatacc tactagcact
    22321 tgtgctttct ccgaaaacaa cccctttcca ctcttcattt gcttcttcag attgcttttt
    22381 tgtcttttca ttttctgatt ctttcatcat aggatcattt ccttcttccg tatccatatc
    22441 ttcactagtt cttggtattt cctccattgt tgacatccct tcaatgttca cgtgtgcatt
    22501 ttcttcgttc acagactgtt gttcgttagc agcaacttca acgacagaaa ttaaaaccgg
    22561 ggtactgagc ataaggagat tcatcattag cgcactgtat tttatacgtt tttttaacaa
    22621 gtgtattcct cccgtaacaa attagaaagc gtttacttaa agtattacct aatttatttt
    22681 tactgtcaat aaaaaacaaa attataataa gtgtatttta taaaaagaaa aaatataact
    22741 taagttgttg ataataaaga gatttattaa cgtaaaaaga ataagttttt ttaaaataac
    22801 gtataaaaaa gagcataaaa caaagtcgtt tgttttatgc tcttctttta ttattttgtg
    22861 ctttttattt tatcaaatca ctttgttttt ttataaaatt tctgcgccta gtgtggactc
    22921 aaaatgtctc aatgcccatt catgtccaac gggatcgaaa cttgccacgg aatctttgaa
    22981 aatatggagt ttgtatccta gattatacgc atcgactgct gtatgcaaca cacagatatc
    23041 tgtacatacg ccggtcaaat aaatatctgt gatctggcgt tctcgcaaac ggatgtctag
    23101 atctgttcca ctaaaagcgg aataatgccg tttgtctatc caataaacat tttcctcttg
    23161 ctcatagtct tggtataaac tttttaaaga gccgtacaat tcccgtccac ccgttcctat
    23221 cacattatgc ggaggaaata agcggttctc cggatgaaag gaatcttttg gatcatgcgc
    23281 atcaatggca aaaacgacaa aatccttttg atcaataaac ttctttgtat gagcagtcag
    23341 ctttttttca attacttgtc ctgctgtccc agtagtcagc tttccatcct ctgcaacaaa
    23401 atcatatgtg tagtcaatcg agatcaatgc gttcatctta gtcctcctta tacgagatgt
    23461 ttgacaaatt cgatcaccat ttctgctgat cgtttgcctg cgtcttcgat aaattcgtca
    23521 aagctttgtg tcgccgagtg atctgctgtg tcgctcattg cacgtacgat caaaaatggg
    23581 atattgaact gacgagctgt ttgtccaaca gcggctcctt ccatttcgca agctaatgct
    23641 tcagggaaat tcgttaagat ttctttgatt ttatctggcg agtcgacaaa tgtatcacct
    23701 gtaacgatca atccttcttt tgcgttcaaa ttcgttgctt ttgctgcttt aaccatttca
    23761 ctgcgcaaat atgtgcttgc ttcataatat agaggcattc ctggtaattg tcctgggttg
    23821 tagccaaatc ctgttgcatc tgcatcaaaa taagctactt tgtctgatat aacgatgtca
    23881 cctacttgta agccttcacc gattccgcca gctgaacctg tattgatcac catgttcacg
    23941 ccgtattgtt ggatcaacag acttgtggta atagatgcta agacttttcc tataccggaa
    24001 cgtacgacga tcacttcgtg gttacctaat gaacctgaaa taaataaagc gcctgcgcgt
    24061 tcccatgata atggttcgct taggttctct ctcaaaattt ttacttcttc ttccattgcg
    24121 ccgataatac cgattttcat ctttttaatt ccttctttct atataaatgc gattgctaaa
    24181 aaaaccacac ataacattag gataacaata ataagagatt tcatcaaaaa agagttccat
    24241 ttggtcgtct tttcccgttc gctgatcctt gttttcgtga ttggtttatt ctttttgctt
    24301 tctttacgat aaaagctggc aatctttttt tcttcttgct gataagctgt ttctgctttt
    24361 cgctgttttt ttaatgactc gcttgcttgt gcttgttgtc gcttgcgaag ttcgcttcgc
    24421 gtaataagcg gtcctttggc cataagccga tccctctact ttcctttggt caatagttcc
    24481 cagtattgaa tcgcataaat cgtctttgca tcacaaatca actgatcttt catcgcttgt
    24541 tgcgcctctt caagagttag atgatacaac tccagtactt cgtcttcatc ttgtgctaaa
    24601 ggattctcga ccttctctac cccttgtgca tgataaatat gaaggacttc atttgcaaaa
    24661 cctggtgaaa gatacatcga agtaagatgg ctcagcgact tcgcacgata gccagtttct
    24721 tcttctaatt ctctagctgc tgtcatttcg ggattttgtc cttctcctgg atcgattttt
    24781 ccagctggaa tctccaaaat cactttttct aaaggttttc gaaattgttt gacaagaagc
    24841 agacgatctt gttcgtcaaa agcaatgatc ccgacaccgc caggatgaaa taccagttct
    24901 ctcttcgaag ttcctccatc tggcaaacga acttcgtcta cagcaacatc aataattttt
    24961 ccgctataga tttctttgcg actgattgtt ttttcttcaa attgctcatt gttcagcata
    25021 tcttctcctg ctttctttgt aatcataact gctttttttt catttttcaa tttttctcaa
    25081 aaactcctta ttagtttacc atagataaac cttagatttt ctctaaatat agaaaatcct
    25141 tctttagtcc gatactcttt ctagtagtcc gtatgctaaa ataagtatgt aatcgaataa
    25201 cgaaaagaat tcaatactca acgataaatg acatggaggg tttattatga taaaacgaaa
    25261 ttggccgtgg cttctagcat tggtcttgct atttctcttt gtccgaaaca atagtttttc
    25321 ttttgttcta ggacttttat tgataggtgt agttttagtt ttgtggggac tctttggttc
    25381 gcgcaggaaa aagggaaaac aagaagaaat tcctgcactg actgacgaac ttgaaactca
    25441 ctatgaaaaa agcggtatga cagcgaatga aatttcattt tttcgacaaa caatgaatca
    25501 aacaaaaaat gagatcaatc aattgcaaat gaatatgcag cagacagcca aacttaaagc
    25561 aatcgatctc cgccatgatc cagtcaaagc agcgaaagct ttattcaaag aattggtgaa
    25621 agaaccaaac cgactgcatg aagcaagtca gtttctttat acgcatctgc cgaatctagt
    25681 tgatttgaca aataagtata atgagatcaa tgaccatgag atcaaaaaca aacagaccta
    25741 tgaaaaacta gaagaaagcg cgcagatcat cgaccagctg tcagctttaa tcgcacaaga
    25801 ttatcaaaaa ttcgttgctg aggatctaga tgatatcgac gtagagatat ctgttgcgaa
    25861 acagagctta aagcgtgata ataaatatga accagaacaa aaggattaac tcttttgttc
    25921 ataaaagaag actcggaaca ttcagatgat gtctggctgt ttcgagtact ttttctaaag
    25981 tagagacatt catgtaagaa tcgagaacag attcaacaag gaggaatttt ttatggatca
    26041 taaaccgact gaaacaaaag atgttacacc agttaacgat acacttgaag atttattgaa
    26101 caacccgttt tcaactccaa cagatacgct gaccacttca caacaagcgg agattgatca
    26161 gctccaagag caacagacag ctgctcgttt aattgacaaa ctaccggcgg aacgccaaga
    26221 acaagctaaa cagctagcag caaaaatcga tgctaatgat gcacagtctg tcatcagcta
    26281 cggatcggct gcccaagcaa aattaagtga attctcacaa tcgatgttga atcatgtgca
    26341 agcacaagat attggtcctg taggagattc cttaactgaa ctgatgtatc gtctccaaga
    26401 agccaatcct gacgaactgc gtgccggaga agggaacatc ttccagcgtg tcttcgggaa
    26461 ggtcaaacaa tcgatctatg aagtgacagc aaaatatcaa aagattggtg cacaaattga
    26521 caagatttca gtgaaattag ataaagaaaa agacggtctg ctaaaagata atctgatgtt
    26581 agaacagctt taccagaaaa acaaagacta ctttgatgca ctgaatattt atatcgctgc
    26641 tggagaattg aaaatggaag aacttcaaac aacgatcatt ccagaagcga tgaaaagagc
    26701 agaagaaact ggcgatcaga tggatgttca gattgccaat gattacacgc aattcctaga
    26761 tcgtctggat aaacgtacgc atgatcttcg cttagctaga cagatcacga tccagcaagc
    26821 accacaaatc cgtttgatcc aaaacacaaa tcaggccttg gctgaaaaga tccaagcatc
    26881 tatcgctaca gccattccgc tgtggaaaaa ccaagtcgtg atcgcattga ccttgcttcg
    26941 tcaaaaagat gcagtaactg ctcaacgcca agtctctgaa acaacaaacg acttattgaa
    27001 gaaaaattca gaaatgctga aaatctcagc catcgaaaca gcgaaagaaa atgaacgtgg
    27061 aatcgtggat atcgagaccc ttcaaaccac tcaaaatgat ttgatcgaaa caatccaaga
    27121 gacattgcgt atccaaaaag aaggaaaaga aaaacgtcgt catgcagaag tagagcttgg
    27181 acacatggaa gaagatctga aacaaaaact gttggattta acccaataga tcacctttcg
    27241 cttgttacta aaacaaacgc ccaacaacag tttattacaa ctgttgatgg gcgtttttct
    27301 tatctttctt ctaacttctc cattggagtc tatttctcat tcatcttgct gtgtccatag
    27361 ccatagccaa aataaatgat cagtccaata accattacga taccgaacac gatccatgtc
    27421 acagtttgca gacgaagcat caatacaata caagtcaaaa tggagacgat tggcaatagc
    27481 ggaacgaatg gcactttgaa ttctccagct tttggtttgc caaacatttt tctcaacttc
    27541 agtaagccta gactaacaag catcaaatag gcgagcgcca tgatattcgt tagttccgct
    27601 aatacattca atgggaaaaa tccggcaaag aatacagctg ccacaccagc ggcataagtc
    27661 gcttttttcg gtgtacgatg cttttgatcg atttctgtca taaacttagg aagtaagcca
    27721 tccttgctga cagcaaacag taaacgagca agtgaataca tcatcgagat cgttaccgtc
    27781 agtagcgtta aaattgcccc tacagcgatc accgcgccca ctgttccatg tcctacatac
    27841 ctcattgcaa aagccactgg gtcattgact cctagttcag tatacggaac gattcctgtc
    27901 aagatcagcg tcacgatgat gtaaaggaca gtagcaatca gtatcgaacc aatgattcct
    27961 cttggcacat ctttttgcgg gtttttgact tcctcggctg ccattgcaac ggcatcaaat
    28021 cccaagaaag caaaaaacac aagagctgca ccatctagca caccggaaaa accaaaaggc
    28081 atgaatggct gccagttatc aggtttaacg aaaaatattc ctacaatgat aaacaacgcg
    28141 atgataccaa atttgacata taccatggca ttattcaaac gtaatgcttt cttggcttca
    28201 agcgacacga tgtaagtgac gaatatcact acgagcaccg caatcaagtc aatgtatgta
    28261 ccattttccg gattgtaccc gccagttaat gcttgtggaa gttcggcccc taaacttttc
    28321 aaaaaacctt gcatatagcc agaccatccg gaagcaacag aggaaaccgc tagtaaaaat
    28381 tccccgatca acaaccaccc tgtcagccag gcagcaaatt caccaaatac aacatacaga
    28441 taggcatatg gcccaccaat cactggcact cgcgaagcaa attctgcgaa acttagtcca
    28501 gacaaaatga caacgattgc agctaagaca aatgaaagtg acagtgctgg accagcattt
    28561 tgattggccg caacccctgt caccacaaat attcccgtac cgatgatcgc accaattcca
    28621 agcatgatca aatcagacgt ttttagttct tttttcatct cactcgtatg attgagattg
    28681 atctctttct tacgaaacaa atccattgaa gttcctcccc attttaggtt ggaaaacagc
    28741 gattaaactg ttttcatata ccctaaaagg gataccacct aaaatgacta aaaggcaacc
    28801 aacaataaca taaatgagct cttttttcgt ttttctttcg ccaaggatga aaatcccacc
    28861 taaagtagag ataatgatcc ccatttgtga aagtgagaag ccaacagcta aaccaagtga
    28921 tttgactgtt agaagcatgc agatgtttcc taagccccat aataatccac agatcatgtt
    28981 tttccacaca aactgatcga ctttaacttt acggaaagca aagaagcttg cgcctaagat
    29041 cattccgata ctttgaggta agataattga catcgcatcc aaattcgccc agttgacgat
    29101 gatggtatat acaccataac caatcgtaga gaagatcaat gctctaaaac ccttaccaaa
    29161 atcaagcatt ttattatctg tatctatttt tccttcgtca tcttgtcggg cagtcaaata
    29221 cgcaccgctt acaagaagag ctaaagcaat aataccgtat acataatctt tcgtttgtgt
    29281 ccattcatgg aagaaaacgg ctcccgcaat cgtattcaaa attaattgaa aaccagtaga
    29341 caatggtagc cctacagaaa cacccatgta cttcattcca tggaactgtc cattttgtcc
    29401 aacactccaa gctaagccgg ataaaaatcc gatcaagaaa atccaagggg tgattacagg
    29461 actaacaacg aaaaagacaa ctaaagaaaa cagaaatgca ccgatcgtca ttcctagtgt
    29521 ttgttgattg gcatcgccac caattttacc acttactaaa ccaatactac cccatgccaa
    29581 catagggact aatgctatta aaatttccat aaccaatctc cttttatttc acatgataag
    29641 aaacttatca gcgaaaacgt taacaacaca agcacttttt ttcgtttcta acgattttct
    29701 aacgtttttc attataaaaa tttaagattg ggaaaaataa agtcattgtt gtcccttttc
    29761 cttcagttga ttcagccgtc aaatggatac ctaatttttc ggccagattt tttgctaaat
    29821 aaagtcctaa tcctgttgaa tgtgttttgc taagtcgacc atttctccca gtaaatccct
    29881 tatcaaagat ccgtttcaag tcttccgctg ggataccgat ccctgaatct ttaactgaaa
    29941 ggctgactcc ttgcgcttcc ttttctatgc tcacaatgat gtttccgtga tccggcgtat
    30001 atttgatggc attactaagc aattggttga agataaaagc gatccattta gcatcggtca
    30061 aaacagtatg atcctcacca acgatctcgt agcgaatatt tttttggata aaataatttg
    30121 cctgactgcg tatcacaggc tgaatgattc cttttagtcc atattcttgg atgaggtagt
    30181 cccgcgagaa actgtcgagt cttgcataat acaaaacttg ttctacgtat tcatcgattt
    30241 ttgataattc attttctagt aatgtatact tttgatcgtc aatatcgaac tcgatcgaac
    30301 gaactagcaa tttagaagcg gaaagtggca ctttgatttc atggacccat gagtcaatat
    30361 aatctttttg gtcttgttga ttactgattg ctgattgcat tacttcttgg tgttcacgga
    30421 tcagctgatt gatatattct tctaccagtt tttcttcttc tgtcctccca ccactcaaat
    30481 aattttgcaa aggggaagtt ttttgtatgt cggctaattt tccccaccat cttctcttgc
    30541 tcaagtaacc acccagcaga taaaaaatca gaaagacgcc ctcaatcaaa gctaaataag
    30601 caattgtgct caaatcaact ttgatgtttg gcgccagcca catcacaaag atcgtcaatg
    30661 caataaaaaa cagccatccc aagatcaatg tccactgatc tttcaaatat ttaaaaaaat
    30721 tcatcttaac cgctcatcct ttcagggaac gatatatccc tgtcctactt ttgtttcgat
    30781 atatccttgg atacctgcct gttcgatttt tcggcgtaac cgattgatgt tgactgtcaa
    30841 tgtattgtca tctacaaatc gttcgtcatc ccacagtgct cgcagcaatt tttcccgact
    30901 taagatcttt ccattgtgct tcatcaaaat aaataataga cgatattcat ttttgctcaa
    30961 atcaatgatc tctccgttga tttccatact tccgttgtca acattcaacg taatgccatt
    31021 gtggctcatc atttcactag ataattctgt gtagttgtaa gaacggcgaa gtaatgcatt
    31081 gatttttgca atcagtacat cgatttggaa atgttttgtc acaaaatcat ctgcccccat
    31141 gttcatagcc atgatcatat ccatattcgt attcctgctg gagataaaaa tgatcggtac
    31201 tttcgatact tcacgtattt tttgacacca ataatagcca tccaaaacgg gaagattaat
    31261 atctagtaat acaagctgtg gttcttctct ttcaaagtct gagaacactt gattgaaatc
    31321 ggtcgttcca aaggtttcaa attgccattt ctcaagttcc tccatgatca attgtcgaat
    31381 gatctcttcg tcttcgacta ccatgatttt tgccataaaa aatccctcca tctttcttct
    31441 tgctactaca atatcaaaga agcccttgtg aaacaagttg gcttacctgg aaaatgtcat
    31501 tttagcaaac gttaaaaaaa actggaaata tgcgatttaa tcgcgtttgt ctcttccaag
    31561 cagcttaaat ttattatgtt attcttaata attggtctat tatctgttat ttttctttcg
    31621 ttgtttttgt cttttaaatt ttcgataaca ccaataaccg aaaagcgtta gcactagcaa
    31681 tatacctaga aggagtataa gtaatcgata aagatggtat ttttttgtct gttctatctt
    31741 tgaagagact tcttctgtaa agggaactcg tcttcctgtc actagtaatc ggtgagtgtt
    31801 cacggtgtaa ggtgtacaag tgataagtgt gactagatcc tgcttttctc taattgctaa
    31861 tgtatttgtt tttgttggaa ggacaacaat tttctcaacg acttcataag cgagcatccg
    31921 accatacact tcaagataga atcggtcatc ttgctccatt tcttcaagat ccgtaaagag
    31981 ttttttctca gcaataccgc tatgggcggt aatcacggaa tgtgtactct ctcctccagt
    32041 tggaaaagag gtgccttgca ggactgtcgc tcctctatct aacaaaagat cattcgtttc
    32101 atcaaataaa ggcaagctaa cattgatttt cggaatatag atggctccga tcatatgttg
    32161 ttcgtaatat tcttttcctg gattttggac atttctaacc gcttgctcaa aaggatcttt
    32221 gacttgtccc attcctggga ttactgatgt atgagcaagc gtctgatttt tcttttcatg
    32281 cactgctaat tgttgctcat gtttttcttc tttatcgcgt tcaagctgct tttgataatt
    32341 ctcgatcctt ctttgatcca aataattgct gagagcatct gctaaaaatg gatatgtaaa
    32401 aactgcagct ccggcaagaa acatcactgc cataaataat tgtaataaaa gactgatttg
    32461 ggtttgaggt ctattaccta ttttcttttt cattttcttc accttcttat ttaaaaaaac
    32521 tgcagcaacc tttataaaac cgattgctgc agcttatttt tgttgcttat acttcagact
    32581 tcattttaga tttacggtac cagctgtacg ctccaatcat caaacttatt ccgattagta
    32641 agaatgccaa gagcccgttc ccaccagtag caggaagtga cccgcgtttc atattcggta
    32701 ctctttctgg ccctggattt tctactccta cgatctgaat ttcttcatta tagcttccat
    32761 aagagatgat aaattcagta aaggctgcct cacctgttgg aagtacataa ccttctggcg
    32821 ccatggtctc tttcatttga taggttccat aatctaaccc ttgaacctca aagtatccat
    32881 ttccatctgc gacaaattct gttgcttgtc cgcttgttgc ccactcaatt ctatctgctc
    32941 ctgattcata aacagctaaa ggcgactccc ctttataaaa tattgcgtat tcagaacggt
    33001 cttcattcca caattcgaat cttgcatctt taagcaattc actgcttgat gcatcatatt
    33061 tttcaaactt tcttccacct gttgtgactt tctctggcgg ctctactcct tcttcataat
    33121 caaattcatc atttcgtccg atttcaataa ccgctgtgtt gttatggaaa tcatccgctt
    33181 ctagttctgt ggaaaccttc aaattatacg tgatcgttaa atctcctcca cgtgcatctg
    33241 ctaatctacc taaagtatct actttggcta ctccattttc ttctgtcaaa atcgtcacga
    33301 caaacccgtt gcttactact tctactatat aatcttgtcc ttttgttaaa atcgtctcgc
    33361 cggctcgcac ttctatttcc tgatcataat aagttagacc aactgtaggc gtatctgtga
    33421 ttttgtaatt tttgataaca gcgcttccgt tttcaaggac agaatcgatg aaataaggaa
    33481 taggtgctgt gatcgtgtaa gaagccgttt ttcctctttc tagatcaata taagaaatcg
    33541 tttcttgttc tccagcttca ttaataatcg ttacttgtct aaggtcgctt tcctctacat
    33601 tcatctgttt atctgcttct ctgatttcgt ttttcggata caaatgcaca tctgtattgt
    33661 atgtgtcttt ccatgtagaa ccatcccaca cgccatccac catatcaggc atcatcactg
    33721 gcatcataac aaccattgga gacgcgattc tggaaatatg agctggcgaa taagtttcta
    33781 agaaaagata gactttatct ctagaagaag gtgcttcttc cgtcacttgg acggtagaga
    33841 ataccgcttc tccagcttca ttcgttgttt gtttgtcaat acttgtcagt cgatatttta
    33901 aaaaccaact ttctgtgtgc cgtttttgaa tccattcaat cgcttcggca gaattaagac
    33961 cgtcttctcg ttccggtgtt aaaggattat ctcgaatcaa atcgtaatat acttccgtta
    34021 cgtcaaacaa atcaaaatcg actcctggaa tattttcttc accaaaatcc gtagaaacca
    34081 atccgctatt cggtcgttct tccggaacag atgagaaacc ttttttgtgt aatgtaatcg
    34141 tcacttcact tggtttttgt gcgacttctt cggctttgac tagttttccg ttcccgaaaa
    34201 tccctattcc cgcagtaacg agtaacagta cactcattcc cgtgacaatc atttttttat
    34261 tcattttttt ctccccgttc tttttttatt aataaaacag cacctaacaa taaaagaatt
    34321 cctagtaaag aaatcaacgt tcttgcttca ttcgtttgcg ggaatacgga ccattttcct
    34381 gattgacctg gattgcttgg accactcggc tctttcggtt tgtccgttgt ttcttttacg
    34441 gtctcgttat aaacacgtgg tgttgcggat tcataggcag agactggaac tttcccggat
    34501 tctaattcag ccatctcctg tccgttaact actacatatt gtggttggcc ttttgcatcc
    34561 acccaaaatt cagggatgat gacctcgatt ctcttacttg cttcatccat ctcgtaacct
    34621 tccacacctt ttaattcttc aaaataatag gtgccagaag gcaagaaacg ttgtcctgtc
    34681 gtaacaaggc cctctttatc cgaaatgaat ttgcttacat ttttgtcatt caaaggatca
    34741 ttgtctgctg gtttgatcca ttgatttttc aagtcattag caggagccat atctaaataa
    34801 tatttccccc cttctatcat ctgatataga gcaaaaacag caccttctaa tggttttcct
    34861 ttttcagttg ttcctctttg acgtccatac ttgaagaagt atggatctct tagataaccg
    34921 acatttttag gatagatatg aatctcttgc agttcctcgg ttgattctgt cgggtgataa
    34981 attggcaaaa tagcagcaat tgggatagct gtctgatcga tatcaacatc caatccaact
    35041 tctggatcaa tcgattcttc gaaaatcaaa taaactgcat cccgatcttg gtttttctta
    35101 ggtgctttga tacgtgcaat cccgtctcct aatccgccaa ccgtatcttt cccagttgtt
    35161 accgaagtcc ctatttggac aagcctttct tctgtgatta gctgacggat attgtttctg
    35221 ttcgtttcag cgatttgctg gacgaattct ttaggagtca tgttttcagc agcttttttt
    35281 tcatgataat aatcggtcat gtcgtaaatg gcaaatgtcg ctccatttag tggcaccgtc
    35341 tgtgaaatga tatctgctgt ttcccctgct tcctcagaga tagccaagcc atcattttca
    35401 tggtattcaa attgatcgtt ataatcgata tctcgaatca tccgtttatg caacacgaat
    35461 tccacgacat cttcccctga ttcttctgcc gacatcgcat gtggaagaag gactgctgca
    35521 agcggtagta aaacaagtaa ttgaagcatc aaacacaaca gctttttcat taccttgctc
    35581 cctccttttt agattgtctg acaaacaaac cataggctgc tcctgcaagc gccatgaaga
    35641 atgcagcaag caggatatag aataatcgtc cggatcctcc tgtagcaggc aacggatttt
    35701 caggatcgtt cccgacacta agctgtaatc tgattcgatt tgtctccaaa agttcatatt
    35761 ctaactcttg ctgtagatca ggcgtctctg cttcttcgtt tggataatac gaaatctcaa
    35821 cttttagtgt acccgcttct tttcctggaa ctacccgatc attttctatg tcaggttctt
    35881 ctcgataact aatttctaaa ataaagtaac ctggaagttt tctatagctg tcaggtgact
    35941 tcacttcctt gatccgatag accccttcca acaagtctga agcattgaat agggaagaat
    36001 cgtttggatc tggtgccaag cctccctcga tgatttcata ctctcctgca ctattttgtt
    36061 tctcaattga aaattctgcg ccttcaagac gtcggctatt catactgtca attttcaaaa
    36121 gttccaaatc gattggcgct agttcatctt ctaaggttac ttgtagtaca ccatcgatga
    36181 tttcatagcc ttccggcaag ggagcagttt cgtcttcgat gaccgtatct tcaatgataa
    36241 acttaccttc ttcattcagt gcaaactgga acacttgatc agatagccga tacccatttg
    36301 gtgcgacaga ttccgagacc tcatattcac caatagacag atgcagaggt tggtcgtaat
    36361 ttaaatcgac atacttttct actcctacgg cacgagaata gaagtatccg atcccaggca
    36421 aacgtttcga ttcttctggt tctaacggat taccagtgta tgctcgatac agcgggaagg
    36481 aagaatcccc cactttcctg atatcgaaac ctgcaccatc taatgtatgg ccttcatggt
    36541 ctaattttct aactcggatc tcccgataat caaacgtatt gtaagcagtg aatgctaccc
    36601 ataaacgatc ctcttcatct gttgtatacg tgagatattg ccaattttct tcacctgttt
    36661 gcttgagttg gatagtccct atagcattat cgtaaagtcg caagatccat gtgtcatttt
    36721 catcaggttc tttgaaacct tctgggttct ggctctcaat gattttgtat tctgcatagt
    36781 tggtagtttc ttcactatcc ttataaacaa atgaatctgg ctctccgatt ggatgaataa
    36841 ctttctcacc atccacgatt acatatttcc cgtcttcatc tactgaatag aacgtgagtc
    36901 tccctttctc ttcctctact tcgttcacac cagaaagccc tttcgctact ggatatccga
    36961 tttccagtcc gttaccatct gtttcataaa gttcaaactc tgcgccattg attggcatat
    37021 tactgccttc aattagttta ttgatattca tgtggattgg cttgaattca tttcgcattt
    37081 ccagtttgac atacaactca tcatactctg tgccttctat gttaggctct tgtacaacag
    37141 aaagcttgtg atattctcct tcataatagg aattcggatc tttaccttcc ggtccgccga
    37201 ctctcgaacc agatgtatat tcatctacaa gctcgtagtg acctaacatc tcatcttcgt
    37261 tggctgcata ttttttgatt tggaattgat acgtctcatc tactaactga taacgtggtg
    37321 gtccagcgat ctctctgatc caaaatatgt cgctgactgc tccagtttca tctcctaaaa
    37381 tcggcatctt cgtttcaaag atcgctattc cgtccgtggt agttttactt gtttcgattg
    37441 gttcggcttc cccactctct ggattttggt catataatgc aaattcgact ccagccaacg
    37501 gctcgccatt ttgacccttc ttgctgactt ggaaattacg gcctttatgt tcgtaacgaa
    37561 tggaagaaga tgggaaatac atccgtccag tagtgatatc attctcataa tcctccaggt
    37621 tctgaatata ggccatattg ttcactgtgc aaaaatttcc gtcttgagct cccgcatcaa
    37681 gttttacttg gtacttgatc ctgaccattt ccccttcacc taaagaaatc ggagaaaatt
    37741 tataagcttg gttttcccgt ccgacatacg ttgtcggagt cgccactact tctggtgggg
    37801 cttgtccatg acgttcttca tcccatattt ctggctcttg gtacttcatg ccgttttctc
    37861 ctggatctag atggtaaaac tgaatatctg ccgatctgcc agctccaaat ggtgagacat
    37921 taaaaccagt ttcatcataa agtgtggctt gctggatcgt tctcttgaag gtagaagaga
    37981 tatcctccaa ggctgtaaca atgtcattct tgttgttcgc attgtaatat cgcggtgtta
    38041 cgccatcttc ttctaaatca gcaatatttt tcaatacatt tcgtccaata gcatctagtc
    38101 gttgtctccc gctaacgttt ccatcgattc ctaaaccaat ggagaagata cttggcgggt
    38161 tctcttgata cttgtttttc agccaatgat gataagcaac tgtgttgatc gcagatgact
    38221 tttcttgcga agtaggactg ccattcgtat tgttattaga agaaccatca ccaacccagt
    38281 gagtcgcttt attatctcct tcttttacct ctccataacg atagtgtaca tttacttcat
    38341 cttctggacg gttaaagtca gatgcatagg taactggatg agtaaaccct gcattagaag
    38401 tattcccaga aaactcctca aaatttctga acaaaacgtc attatcttca gcaatcttat
    38461 cttccatcac agtccagttg ctcaaactcc attagtgctc gtacgataac ttgactgaat
    38521 cggtgcataa ctgaaggtcg gtgtcccatc tcccacaacg attaggattt tttctggatt
    38581 tctattttct ccgccattgt ctttatacaa tgtttcatag ccatttttaa gccctagtgt
    38641 aagcggagtt cctccgattg gtgtacgatt taatgctgta ttctcacttc ccgtcaaacg
    38701 attgatatca tttgtcaatg gaaagatgtc cgaactgatt tgctcatggt tattgatagc
    38761 tgtactatta tggtaaaaat tcaccatacc gattcgaata tccagactcg ggtcagagag
    38821 cagatcttta ctcatttcgt ttactgcctc aatcaacgca gcatttttag tttgactatt
    38881 ggtcccagcg gttaattcac tcatactcgc tgacttatct agaacaaaaa cgatatcgat
    38941 tggactgatt tcctttttct cgcccccgat gacatctaga tagacattgt aaagggttgt
    39001 tgcatcttca ggatgtagat cagatgctgt gctgcttggc agaacaggtt ctacccattt
    39061 tttgatgtac gccccgttat aatccaagta actgttttca aaattccgtt catttcccca
    39121 aagctgaacg gtttgagctg gaacgtttct atcttcttcg cctgcagttg atccattatt
    39181 agtagcatag tcgtaatttc gccagttcgc tcccccgttt gtataatcac tatcatcgat
    39241 caagttctct ccgtcatatg gcgagccttt gtctccttga tagcgttcat tgctttgtgt
    39301 ccaatttcct aacacttttg tatagtcatt cgttgtaaac ttcgggtagc gatgctgttc
    39361 gttttcaact tctccgctag gatagatata ttcatagggg tcttgcgtag ctgttggccc
    39421 aagacgctcc aaaataccgt tgaataactg gcgttgaatg cgctggagtg cttgaccgct
    39481 gggtacgatt ggttcgtcca gcttttccat ctcattttct tcgctacgtt gaatttcagc
    39541 ggaatcttct gtatcagttt cattttcttg taattcttgg ttatctattc tttcatcaac
    39601 caccacttga agaggtagtt acccttcgtt cacatcgggg atcttttctg tttcaaaaat
    39661 caatgtgccg gtttctgctt cttttgaata aacttttccg acataccatt cttgaccatc
    39721 gatcgtctcg acttttaggt cttctccatc ttcatcatag gaggatagac ctgttccacg
    39781 aacgtttttt acggtaccaa tcccggcggc tgccgcatcg attgctaaac gtattctacc
    39841 ttcattggca ctttcctttt tttcaaaagc cagatgccat tcaagggttt cttctttttc
    39901 aatatacttc ccttcaattt ttgcatagtc ctcatctaag aatacctcat cctcctttgt
    39961 ttctgttgac tcagcagcta catccagggt cgtcatatga tagactgact ggaaatatgg
    40021 tccaaatagc aaactgacag ttactaactg caaaagcttc aattttaacc ctttcacatc
    40081 cttatactcc tttcaaaaat atttgtcttc tttcacaaca atcaacaaaa caatgcccat
    40141 ctaattataa tttaatttaa ttttaatttt aaatcaaatg atatcctttt tagttaaaaa
    40201 acaccaatta tacaacattt attattaaaa ttaaattata aaattttata acgttctcat
    40261 ttaacaaaac ttaagttatt aagacaaatg aataaacaac tacgctttcc tcgaaacaaa
    40321 aaaataaagc acaaatgcgc atttacgcac tcatgcttta ttcgtacaat taattcagat
    40381 aacggcagcg cataggatgc caataacact tcctaaaata gctcctccta aaatgtcagt
    40441 aggataatgt aaaagtaaaa aaatcctcga ataagcgatc aaacaagcaa ataaaaaggc
    40501 taatattcct gcaactggac ttaattcgaa caacgcagct actgataaaa aggctagcgc
    40561 tgtatgtcct gaaggaaaag aagaagtctt cggtttactt gtgtaaagga caagccgacg
    40621 atttttttca taaggtcttt tccgtcttgt cgtttttttg ataaaaagca aaccaacaaa
    40681 aaaatagatc aaactgccga taagaatggc tagaccatat tctctagtat caggtatcaa
    40741 gactaaaaca gcagcaagga gcaaccaaat aaaaccacca ttagagatat tactgataaa
    40801 tttcaaaaaa ttgatttttc gactatccgt tttccgttgc ttggcgaact tgttgataat
    40861 actatcatcg attttagcaa tcaaacgcaa catgttattc ctccttttta agaacctttt
    40921 cttgcgtacg atggataaaa agcaggactt gaaaataaaa caagaaactg aaacctaata
    40981 aagcaaaata gattggtcct gcaaaccaga atgcgacaag aaggatcaac gtgcctgcca
    41041 aatagaaaag cgcgcttttg aaatcattaa aaaacaagaa aaatgcagta atccaagaag
    41101 cttctttttg ttccagttga agcaagattt tgtaactaaa gagaagcgcg cttaatagaa
    41161 gcaaaaacaa cgtagtatac atcaatgtat agccaattcc cccaccccaa tagcggaaaa
    41221 tctgataatc gatcaataga agaagaaaat aaacacttgc taaactatct tgctttccat
    41281 aaagagagaa gttctcacga aactttttcc agaatagtga accgagcttt ttctcttcat
    41341 tttttttgta atgataaatc atatacagaa ctgttcgact tgcagttcct aatgtgaaaa
    41401 caggcaagac gcacaggaac catagtagct gtaaatggat aagacgtgga atccattcaa
    41461 tgatttctaa gaaataatca ttggcttttt taccaatcga tcgattcatc atccttttga
    41521 acctcctgtc aaatccatcc cttcaatgaa ataacgttgt gcaaaaaaga acagcaaaat
    41581 cgtcgggatc aagacaagtg ttgctcctgc catcagataa ttccattgtg tcgttgcttg
    41641 gttctgaaaa acttgcaagc caatctgtaa cgtgtatttt tcttgatctt ggatatataa
    41701 cagaggacct aagaaatcat tccaagctgc gttgaaggaa ttgatcgcaa tggtaatcaa
    41761 ggcaggtttc gtcaatggaa gcatcaaatg actccaaata tacaaatgat tcgctccgtc
    41821 gatttcagca gcttcgatca attcattatt gatcgataag taaaattgac gcatcagaaa
    41881 tatattgaac gcattgccga agaacgatgg aacgatcagg ggcaaataag tacctaccca
    41941 gccgatcttg gagaataata catattgagg gatcatcgtt acaaaccccg ggatcatcat
    42001 cgtagaaaga accaaagcaa acatcagctt tttcccagga aaatcaagct tcgcaaatcc
    42061 ataagcaata aaagaatttg aaaggacatt accgatcact actagcacag tgatgaataa
    42121 tgtatttctt gcatagcgcc aaaaaggaaa ggcggcaatc gtatccagat agttttccca
    42181 tacgattttt tctgggaaaa aggtcggagg ataacgaacg atttcttcca ttggtttcaa
    42241 tgaagtaaac accatccaaa gcaatggaat gatcaaaatg attcctatta ctgtcatgag
    42301 gacataactt agtatttttt ttgtttgccg attcacactg gtctttttga aataatccat
    42361 catttgccgt cacctccaga ataatagacc cacttaggtg caagcttcaa attgacaaac
    42421 gtcagaacca acacgatcag aaacaggatc attgacatag ccatcgcata acccatatca
    42481 aaagctacga acgccttgtt ccacatatgc agattataaa aaagcaaaga atttgcaggt
    42541 ccgcctgttc catttttcgt catgacataa gcttcttgaa aaatttggaa agaaccgatc
    42601 gtagaggtga tcacatcgta aaaaataata ggagtgatta atggcaaagt aatacttttg
    42661 aactttcccc aaacgcctgc tccatcgatt tctgctgatt catataaaga tctaggaaca
    42721 ttttgtaatg tagctaagta aagtagcatt gctcctccag aactccatat tttcatcaaa
    42781 atcaacgcag gtttcgtcca ttgtggatca aacagccaag ctggtccagg gatatggaac
    42841 cagcccagaa atgtgttgat caatcctgca gatggagaaa gcagctgcat ccataagatg
    42901 tagactgcta ctcctgataa gactgccggt aaatagaaag ctgtacggaa tacactgatt
    42961 cctttgattt tttgattgag tactgtggct aaaaacacac tgaaaatcgt cgtcagcggt
    43021 acattgaaga tgacgaaata aacggtgttg tataacgatt tccaaaataa atcatcgtga
    43081 acgaacattc ttttgaaatt tgctagacca atgaaattca tcttggatgt caaattataa
    43141 tcggtgaaac taccaataac tgaaaaaagc ataggcccta gcataaatac caagaacccg
    43201 ataataaaag gcgagataaa taaataggcc catcttgctt cttttttctt tcggatagat
    43261 aaacgcttca aattttcttg cctcctctgt acctagacag tcaaaaatgg attattgatt
    43321 ttgcttgact aagttttcta ctgctttttg tgcatctgcc aatccttctt ttggtgattt
    43381 tgttcctaaa agaatctggt caatctgttc attcactaat gtcgtgtaat ccggagcatc
    43441 taaaggaact ggtgtgatca ccgtattttt aaagttttcg tccgccattt gatagatcat
    43501 ttttccttta tccgttaggt tgtcattatt cactaaattc tcattggctg tcttgctcgc
    43561 catgatatca aaactttttt cgccgaattt ttcttgtact tctggagaag aaagatattt
    43621 gatgaattca taagaggcct caggatcttt tgctccgtat ggtacttcca agacgaatcc
    43681 gccaccccac gaccaatggc ctgaaccttc ttctttttct gggagctgca tcacgccaaa
    43741 atcaaaatca tccggtgcat tttccatcaa actagagtaa taattgatat tttgggcacg
    43801 catggctact aatccggaaa taaatggatc agatacacca gacccaaatt cggcttctaa
    43861 tttattgatc gtatttttcc cataataatc ttgccagtct tggatccact ccaaggcttc
    43921 cactttattt ttagtatcaa tcttgacttt ttcatctttg tcaaaccaac tagtcccgtt
    43981 atctgcgttt agcgcccata catcagcccc taaattccat aatggataaa aaccgatgcg
    44041 tgtaaattct tttccttctt ttttatctag tttacgtgct gtttcttcta attcatccca
    44101 agttgtcggt agatcttgtt cactgattcc agcttcttta aataactttt tattataaaa
    44161 aatgacttgt gtatctgtat tgaatgggat cgcataagga tcaccttcat attctactgt
    44221 atcccaaagc tgcggataaa aatccttaga agtgtctttt tctacatatt tggagagatt
    44281 agttgcttgc tgtgcttctg ctctttgggc aacggaattt atgtcctgta caataacatc
    44341 gggtgcattt ccagctgtta ttgcagataa agatttagtc cagatgtcac cccatggctg
    44401 atacttataa tttacatgga tctcgttttg tgattgattg aaatcctcaa tgatttcttc
    44461 gatagcttct tttcgtgcac cggatcccca aaaggaccag aaatcaatat tttttcttcc
    44521 atcacttgtt ttttcagaag aatttgctgc acttgaactg gcatcgcttg cattacttga
    44581 tccgcatcct cctaataaaa acaatgctga acttgccagc aaccctgtaa acaataattt
    44641 tttcatattt tacctccaaa ttttaatgta accgatgccg gttttaatat aacgatatca
    44701 ttttgttctg aaaataacaa tttataaggt atgattctaa aaaaattatt aatgatacca
    44761 atactttata taattcgcga gcgctttctt tgaatttttt aatctttcgt agcagaatga
    44821 gaatgtatta aaaatagatt aggaggaatt ttgatgttta gacaccagaa agaattgcag
    44881 tttgaagcaa aaccagatcg tccgaatcca ttaatcgcga aatatctgca ggagctgatc
    44941 ggcggccaat atggcgagat gagtgtagct atgcagtacc tgttccaagg ctggagctgc
    45001 cgaggagaag aaaaatataa agatatgctg atggacattg caacagaaga aatcggccac
    45061 gtggaaatgt tggcgacaat ggttgctcgt ttattagagg gtgcgcctgt tgaagatcaa
    45121 gaagcagcga tgcaaaaaga tccaacaatc ggtgccatta tctctggaat gaatccacag
    45181 cacgcgatcg tagctggctt aggacctcgt cctgctgaca gcgtgggcaa tccatggagc
    45241 ggtgcctata tcattgcgag tggcaacttg ttagcagact ttagagctaa tttaaatgcc
    45301 gaatcacaag gaagacttca agtagcacgt atttacgaaa tgatcgatga tcgtggcgta
    45361 aaagatatgc tgtctgttct ccttgcaaga gatagctatc atcaaaatct atgggaatgt
    45421 gcagtgaaag aattagaaga aaaagaaggt tcaatcttag tcccaagtac tttcccgcgt
    45481 gacaaagaac gaaaagacat tgcttatgac ttctataact tctcagaggg agaccaaagt
    45541 agtgaaggtt cttgggctag tggcaaagca ctggatggcg aaggcgaata tcaatggttg
    45601 aaagaaccta agatcgaagg cgctgcacca aaattagaac cagtaacacc aaaaatgtat
    45661 gggacacctc cattcaagaa ataaatatct acccgtagaa acacccgttt tttgttccac
    45721 acgctttgtg agcaaaactg actaaagtca ttaatcataa ccacccttca aaagggtggt
    45781 tttctctaga gctataagct caaatcaccg gccagcgcct aaagacgctg gctttcatat
    45841 tttatgttca agccatattg cctttgccag ttttgcccac ctcttaaaag gtttatgtac
    45901 tactccttag cccttaaaag gatcgtctta ctctcgtaca ctcagcttat ctaacgcact
    45961 atcatgtttt tcttgttctt gaatgtactt tttgatggtc gcttcatttt gtcctacttt
    46021 tgtcacatag tatccttcca cccaaaagtg tcgataccca aatttatatt ttagatttgc
    46081 acaatctctt gatgatctcc tgaatattgg ctcgatattg attataaatt atttttcttc
    46141 tatactttgg tgtgaataca atgtggtatt tacacatcta ctttgtacgg gctaaactat
    46201 ttccctttat tgctccaccc gcatagcaag tggttttgta tttcaatcgc tcggcgcgct
    46261 caattaggtc taaagacaat aaatctaaaa acccgctgct tcactgacag aaacaacggg
    46321 ttttcagaaa aaaatgaaat gaaaaagatc tcttacggca atctatttta tttttttgat
    46381 tttttataaa tggaaaatgc ttcaagaagt ccaagaaata aagccgtata aaaacaagaa
    46441 cctatgaaat ctttatttat tagatattca acagaaatcc cgataacact agccaacaat
    46501 atatttatca gaagtgtaaa ataaggatgc tttttataga atagaactag tgttgttttc
    46561 atagactctc ctttcttcat atttccaatt aatcacaaat tcacggcatt actagaaaaa
    46621 ttaaaggggc gcagaagtgg aaaaatactc ttcgactttc cctacaaacc aggccatctt
    46681 gtgtttaata actataccaa atctaaggta cctctaaatc taaattccat ttgtggcggt
    46741 gacctccaat ttttaactct tctatctccc atccagtata cataaccttg atacttcgac
    46801 cacttatata tcgaacacac aaatacctat ccattgcagg agtactacct aacttagttg
    46861 ctacttgcat ctaaataaca gctgaaaaga taggacttac tcttagtaaa gtatctgaac
    46921 tattaatttt taaactatca tttttatcct caactacatg cacatctgtt gcaacttcac
    46981 tttctgtctc atccagataa atgattaagg aatcgggaat tgcaatatct tcagctgacg
    47041 ctggaatagt tgagctaaat tagtcatcat atctttatta taaaataacc aacagcaaaa
    47101 aatacaatga aaaacaaact tggaactaat gtatcattaa taaatgttga aaaattcagc
    47161 aactcattac tgtatgattt tagcagccca accaacatat accctataaa agctaataag
    47221 atggttagga atcctttaga atttttactc attcatagac acttccttaa ataactttta
    47281 ttatagaagg tattgtaaat aataatattg acaaaaagtg actcaaaata aaaaaaacct
    47341 tacattatac tggaatgaac tgtattgata gtgtacctaa aagctctact gacataagat
    47401 cgtgtaatcg gtaaagtaat tttattaatt atacgggatg taatcaatta gagaataaac
    47461 taatcataaa aggtactttt acattcataa ttgtcgcttt gagattctac tttggttcac
    47521 tatctgaccc aattgcacat tttcgatcat tacaagtatt ggtgtcgtta gaacaactaa
    47581 ataaaaacta gcggtagatt tttcagaatc tatgctaatt tctgtatgga tgttccagtg
    47641 atggcaaatt tctcttttca ttgtttttct tgtcgcatga tatgcctttt tgtgttattc
    47701 agttaaacta tagaaattct ttcctagaca gatcttgatc ccaaatttta cgtttttgag
    47761 catcgatata gtttaaaatg acattactca tatctaaaga gtttagattt tttaggacta
    47821 aaactgtcag ttgttctttt tcttctttct gttaaagtat tgtcgcgact tttcgtatac
    47881 gttaagatat gtcgtgaaaa aacaagtttt gtgacacaaa aaaacgaatg acttgaggaa
    47941 atcacctcaa tcattcgttt aaaatgctat atattcttta gtttaagata cggaaattaa
    48001 tgccatcgac cacactagta gaatgaacga catttacttg gccttttttt aatttcgtta
    48061 tgtttagcat ataaaaatat tatagagttt acttacaatg cttaaaacat atactgtata
    48121 atctgatcaa ttttagccat gtcttgcaat ggtaagtttt ctattttttt gagttttcgt
    48181 tccttaaaat caagagattt taattgtgta ataattactt gtccttttat atctagctct
    48241 tcaggtaatg agtaacgtgt cggtaaattc tttatagtgg aagtaattgg acatatgacc
    48301 gaaaacattg ttttacggtt aaattcataa cgagagacga ctagtcctgg tcgtcttttt
    48361 tgaatttctt ttcctacgga gggatcaaaa tcaatccata caatatcacc ttttttagga
    48421 atataaattc tttcttctga cactataaaa tttctctccc ttcaggagtt aaatcttccc
    48481 attcgtcttt ctcataatac tcggcctctt ccccaccact aaatggatct tcaatttttg
    48541 gaactaacgt aattgttcca tcatcagaat acacaacgat atattcttgg ttttctgaag
    48601 gtttctttcc gttatcagaa ggtaaagtta ccactacaga acttccttgt aatctagatt
    48661 ttgtaacaag cattatcatc actcccttaa taaaagtata ctatataaca ctaagtaacg
    48721 caaaattccc ctttgtaaac tatctagaaa attgttttgt ttaaagtata tcttattgga
    48781 tataaataga aataaattgt agccagttca ttttttcttt aactaaaaaa ataatccaag
    48841 aaacattgaa cctatggatc caaaagctac ccaaatacta tagctaaccc cccgctacct
    48901 tcaattttgc agataaaacg ctttgggaga aaatttcaaa gacaacaggc catcctatca
    48961 tgcccgatta taaacaaaaa gctggctatt ccttttgctc tgacaaattt caattgggaa
    49021 agttcacgaa actagcaggt gaagaagttt caactgttcg gatcaaagaa tgcccgcttc
    49081 aaatagaaac attggttcaa cgaatttcaa ctagacaaga ctttgctatt gtagaacgtg
    49141 agatcgtagc tatttttgta gaagaaggga ttttacatga tccaactcat atcaatgtgg
    49201 ataaatggca acctcttatc tataaattca gagaatatac aactgccaac cagtcgttaa
    49261 ctttgaattt tagattccaa gaattcaaag agtcataatg ataaacatcg ttaggtataa
    49321 ataaaaaaga ctcgcagcac gagtaaaaaa caaatagaag ctatacatta gaaaggtcga
    49381 ctgtgaccct atagatgcag tatatgcagc ttatgagcat ttcttctgtt ctctttgttt
    49441 ttgggatctg tgctgaagtc tttttcgttt tttgccgctc tttctttgaa aaatcgatta
    49501 tgttatacct tctccattac taattcaggc atctgctgag taatgatttt tcgcgcaaaa
    49561 gaaatatctg ttacccaagg ttcgatttgt tcttcagtca agacaagcgg cattcggtca
    49621 tggattggtg cgactgtgcg gttaggttca gtagtcatta tgattgattc tgccattttt
    49681 tcatcctgat ggctacgata aaaaccgcca atatacacta ttttttcctt atttgaaaac
    49741 ataaatttgt ctttttcttc attccactca ttgggaaaac acaacgattt tgcaaaaatg
    49801 gttgatgaaa ggtctttttt tcttctactg tctctgcacg ggcattaatc atcaattgtc
    49861 cttttttaaa tccggtaaat ccccacttca tgatttccgg agtgaggatg ttttcttcct
    49921 cttttcttaa cgtcacaaca agatttgacg gaaaaacttc tccagctgct aattctgctg
    49981 cctgcttcgg ttgtttcgtc tgggcttctc gataataatt ctgaaggagc tctgactcta
    50041 gatcaaaaaa ataacgacca cacatcctaa tccctcccaa tctttttttc tatcatacac
    50101 tgcaacaaga agttcgcacc aacaaaacgc tttcaatttt tgtagaacta aaaaagttgt
    50161 gacaagtgac aaactctcca gtgaatggta ttctcctgcc aactcctcgg tcacaagtca
    50221 caatattcaa caaacatgag aagctgcttt ttgaaattgt tccttgtgac tcggagtgaa
    50281 acggcaggct tacgacctct gggtaaacgg tgttcaaaag ccagtttctc ggtattaagc
    50341 caaatttatg caaaaatgta gaaagctatt ttcacaaaat ttttcttaat actcgaaact
    50401 aagcgacttt ttcacaacct cttccttaaa cggtgttcaa aagcttgcat ctgcggtaat
    50461 aagcccaacc aaacgaaaaa tatgagcagc tatttttatt tggctgttct tattacttga
    50521 tgcagggcag ctttttcaca acctctccac taaacggtgt tcaatcagct aaccttcggt
    50581 attagctcaa aaaacggcaa aatatgagga actattttgc cgtttgtttc tctaatactc
    50641 aggtcaaagc gctgatttca caacctctaa tacacggtgt tccagaagta gcttcttcga
    50701 aaaataagcc gaaatttcac aaaaatttga gaagcaattt tcgtaaattc cttcttattt
    50761 cttgaagctg accacttctg tcacaacctc taattattaa agaacctttt gcgaagttaa
    50821 caatctttct ttgatcaatt gaaaattctg cctaagtagt gatagatcct gtgtgacttt
    50881 caacaataag atacttccct ggatttcagc aatcaacgct ttggcttgac ggtctgcttc
    50941 ttcatcggac agtttttctt cagaaagtgc caggatattt tgtttcgtat acttgaccca
    51001 ttgattgact aattctagta gcaacagacg gtattcttca tccactgtac tcaactcaat
    51061 aatcaaatta cctacaggac agccatgata agtgatctgt gtctcatgat cagcgaaaat
    51121 ccagtccaac atttcttcta atgcttcttc tggctgtttt ccagcattta agatgtcttc
    51181 gaacaattct gtctgccata cgtccatatg cgcatggatc accgctagac aaacttcttt
    51241 ttttgaagaa aagtaataat aaaattgacc ttttcctgta tcagaagctg ctagaatatc
    51301 tcggattgac gtttcatgat agcctttttt ataaataaga tctttggtcg cttccaagat
    51361 cttttccttt gttttcaatg atattctcct ttttcatttc tcatagtcct atattataca
    51421 gtaaattcat cattttttct tcttaatcgt ttaaaaaaga ctgtgccaaa ttatctgaca
    51481 cagccctcac tataaaactg ttctcatata gctagatgtt cattgattca agaactgcga
    51541 ggacaaaagc aattcctatc ttatgatagt tgctctaata cttcctctgt tgtcatcact
    51601 tgatctgcaa taaagccaaa gttcgtcaac gctgcatcca ttgcttcttg gccaggagca
    51661 ccaattgcat ctgtcgctac cacaacattg aatccactct ctaccaattc acgcatatgg
    51721 gaatcgctac acaagtttcc gttcattcca ccaagaatta ctgtgtcgat tccatttttt
    51781 ctcaattgga gcgccaaatc attgctttct ggtccaaaga ttttatgagg agagctgatg
    51841 atcgtatttt catccaaata aggtttcaat tcttcgataa aatcggctcc tgaaccttct
    51901 tccactgatt catattgact ttttctagca aacatctgct gctcaagcat catatgttct
    51961 cctgcaccgc caaattgcca tttatggtca tgtgggtaaa aataatgagg agaaataaag
    52021 agtttgtatc ctttttcttt tgcttgtttt accatttcaa tcatattttc gatcgtattg
    52081 tatttttcta agatatcttt tgtcaaacca aagccaccgc ctgctggttt caagaactcg
    52141 acttgcgggt cagtgagaac tactgctgta tttttattat tgaacatggt ggattctcca
    52201 ttcgttattt attttaatac atcatttaga gcttcactca ttgtcggatg agaatagatt
    52261 tgatctctca ataacgtata aggaagtttt ccattcatag ctagcgaaat caagttgatg
    52321 acttcatgag aatcttccgc atagatactt gcccctagaa tcaagtcagt ttcagggtcg
    52381 actaaaactt tgaatacacc tttaggatct tctaatactt gtgctttagg gacaccgctt
    52441 gtcatatact tgaataattt gtaattgacg ccttgtgctt tggcttgttt ttctgttaaa
    52501 cctacattgg ataaagtcgg agtgataaat acactgtaag gcacagcttt ccggttattc
    52561 gttgttcgtt tattctcgcc cttcaactga tccataatga ttcgataatc atctagagag
    52621 atataagtga actgcaatcc gcctttgacg tctccaatcg cccaaatgtt gtctgcatct
    52681 gtacgaaggt attcatccac agcgattgct ccgcgatctg ttagtttaac atctgtattt
    52741 tctaatccaa gtgatgctgt acttggtttt cttccagttg cagccaaaac ttttgacgct
    52801 tggattgtta cttcttggcc atcttctgta aaggtgacgg cagctgttga ttcttggtct
    52861 gctacttgat ctacagatac acctagatgg aattcgattc ccgcatttgt catgtcttct
    52921 aaaatcattt gcgcgatatc ttcatcttca cgtggaagaa attcagaatg ggcatcaaga
    52981 acgacaactt tagatccgta ttcattgaac attgatgcaa attccaagcc aatatatcca
    53041 gccccgatga tcactaattt ttccggtaat tgttcctgat ccatcgcttg cgtagaatca
    53101 atcaagtagc gacttgtatt caatcctttg attggtaaaa tgattggttc agaaccagta
    53161 ttgatgaaaa tccgttcgcc ttcaacaatc actttttcac cattattcgt cacttcgatt
    53221 tgatggttag aaagaaaacg tgctgtaccg tccatcactg tcccagttgc ctcatcgctg
    53281 atcatatgat aatttttggc gcgaagcatg cccgtcaatt tttctttccg agcaacagcc
    53341 tctgtaaagt cgattcctct ttctccattg aaaatcaatg atttagaagg aatacagccg
    53401 atgttgatac atgttccgcc atacatacgt gttgactttt caacgactaa aaccgattca
    53461 ccttttgaag ctaacgcctt cgctaaagtc ttaccgccct ttccaaaacc gatcacaata
    53521 ttttgatatt tttccatcat ttttccctcg cttctttttt acctaccgat tggtacaaaa
    53581 atatgataac cgataattgt ctattctcca aatcatctgc tttatttgtc aaaaaaaacc
    53641 agacaaaaag cggtcctttc acgtttttag tctggttcga tttcctttat tcttctaaac
    53701 aatcgttact tctacatcga tatttcctct agttgctttg gagtaagggc agaattcatg
    53761 cgcatcttct gcaatttttt gggcttcttc ttcgctgatg ccatcgatat gcacttctaa
    53821 tactacaccg atctgatagc cgccatcatc taaattataa agagagacac gtgcttttac
    53881 tgtggactct gctgtcattc ctgcttcttt gatcatatgt tgtaccgccc cattgaaaca
    53941 agaagcataa cctgctgcaa ataattgttc tggatttgtt ccttctgcat ggattcctgg
    54001 aggagtgatt ttcatatgca tcgagccatt tggtgcctcg acttctccat tgcgcccgcc
    54061 atggttgatc attgctgttt cgtatgcttt tttcattgta ctgctccttt cgattgacca
    54121 tttgctactt ggctataatt atagtgtatg acaagtaagg cgctttctac aaaaattctg
    54181 cttattcgaa taccagaatg ccgtcttcta ctatttttcc aaaaaacaaa aaaatactac
    54241 tcgtgaacaa cagcgtcata tttgttccaa aataaatagc aatcttttct acataatctt
    54301 ttatatgatt gattttaaga tacatatata ccagaaagtt gaccccataa accaatactg
    54361 ttaaaaaaat aaccatattc gttaccattt tttcctcctt ttgctggtct ccctaccagc
    54421 actcgattta accataccac tttttttgcc gtccaagcaa ctagcctttc aaaaagactg
    54481 gtttattctg ctgttaatga ttcaagatca gaaaaatgtc cgaataattt tgctaatttt
    54541 actaacgcca acttgttctt tccgaattca tcattttcta tctgtaatac tagtaacggc
    54601 tcatgtaagc ttaaacggat caaaaaccag ccgtttccgt atggctcttc tagatcatat
    54661 cgaatacctt cttcattttc cgggtcgaag ttcatccctt tttcttcttc caacagtcgc
    54721 ttcatttctt ctaatatctt gtttccttgt tcgcgtggtt catcgctgaa caattttaat
    54781 cggatttctt gtacttctac gggctgtttc aactctttga tttgttcatc taatgtgata
    54841 ccttttcttt ttaattctgg caaaagcatc aggatctttg cgatgacata tgcaccatca
    54901 tccagaaaat agttttcctt gaatgcagcg tgtccgcttg tttcgatggc tagctgtgta
    54961 tctttcccaa gacggttaag ttctaatgct ttattgatta catttcgata gccggaaata
    55021 taacgaactt ggatgcctcc tttttcttca atgaatcttt gtagatgaga agaagtaggg
    55081 gaattcgtca cgattcttgt tcctggatgc tcttttaata cgattgtact taatactgcg
    55141 atcaaattat ttcgattgat cactgttcca gaagcactga caactgcaga acgatccaca
    55201 tctgtatcga aaatgatccc aagatctgct tcatttgcta aaacagcctg cttgatactt
    55261 tccatcgctt ctttattatc aggatttggg atatgattag gaaatcggcc atctggttcc
    55321 aaaaattggg aacctgttga atccgcacct aagctattca atactttttc agcaaagaat
    55381 ccaccagcac catttccggc atcaacaatg attttccaac catttagtgg tttgctttct
    55441 agtgttccaa tccccttttt aatttttgtg actaaatctt gcgcataagg tgtcaaaagg
    55501 tctgcttttt ctacgcttcc agtttgttcg ctttttattt tttgctgctg tgataggata
    55561 aaagcaatat cttctttttc tgctcctcct tctgaggtaa agaattttat tccattataa
    55621 taatagggaa gatggctagc agtcagcata accgcagcat cgcacgagaa ctgttcaaat
    55681 tgagtggaca taaacatagc aggcgtagta gctaattcga aatcgatgac atgtatccct
    55741 tgttctttca gactttggat caacgcctct ttcagtgctg gtccgcttat cctactgtca
    55801 tgaccaatcc caatcgtcca ttttttattt ggatcggttg atttcttctt tttctttatc
    55861 cagtttgcta gtccccagcc gatctttttt accatgtctg tcgtcaagtt tacttcatat
    55921 ccttcaactg gtaatgcgat tcctcgaata tccgatccat tttgcagcgc tttcatatct
    55981 ttcatataaa agtcctcctc atttattccc tcattttttc cagcttttct gcaaatcgct
    56041 gtgcttcttc ttctgagcgg caaataataa tgaatgtatc tacaccggcc atcgttccga
    56101 caacttcagg gtaagccact tcatctagcc aattcgttac cacatcggca ccatttcgtt
    56161 cagtcaatac gataaccatg aactgaacag actggatacg caaaacctcg cgtctaattg
    56221 ctgtacgcaa acgttcttca tttaaagaaa cagatggctg gttaaataat gtatagcgta
    56281 ctattttgtt ttcattttga ctttttacta acttcatttc tcgaatgtct cgagaaatcg
    56341 ttgcttgagt cacatcggcg cctgcttcat gcagccgcgc aagcagctct tcctgtgtcc
    56401 caataggttg ttctgtaatg atctggcgga tcagtgcttg tcgctgtttc tttttcatat
    56461 tagacacctc tcaatgttga ttatagcaaa agataagtaa tatttcttca tattttggta
    56521 ttttttactt ttattttttg ttttcattca ggttgctaac ctttttctat tttaacacgc
    56581 aaaatcgtct tcattttttc aggtgctgat tttcttggat cgctgatgta aatctctttg
    56641 tgttctttag aagctctttc atagccttct tttgcgatga atgcttctaa tttctcaaac
    56701 gttgctggtt cttcggcata gggcccgacg tgtaagattt gggcacaaag accttcttcc
    56761 atctttttga atactacttg ttctttcaag tcttccggaa gtttgctaga acgctgaatg
    56821 gcttcttgtg ctatcgcttc tgtaacaaag tcaggctgtc ggatcatcaa ttgataagaa
    56881 aaatgttctt ttttcatcac tggttcatgc aaatactttt cttgcagtcc ccattgtcct
    56941 tccagtggat agacagtata catctgataa tcaggaatca gccaattttt tttaggcgac
    57001 atgcgtattg catagctgac tgcatataga caggctactc ttcgtttaaa gtcttcctga
    57061 ttcgggtcgc cgatccctct gatgctaaag aatgattttt taggaacctc tagtatttgc
    57121 gggctttttt tcatactata gctcttgtct ttacgccatt caattttttc catttttctt
    57181 cctccgcgaa attccattta gttatttatt atcatacctc tttttgagtg acttggctaa
    57241 tcgtgttgac actatttttc agtttgtgct agaataagtg aagtaaataa atcgtacaga
    57301 taacacgttt cggcgtgtcg agagagaggc ggtttctatt tttataatag aaatcactct
    57361 ctttttttac gaaatttttt agaggtgatg taaatgacaa aacaaaaaca gctgctttta
    57421 gtacctgcag taattgcaac agggatgatg tcttttgcgg gcgtattgat cgagacggcc
    57481 atgaatgtaa ctttcccaac tcttatcaga cagtttgatt taacgactgc acaagtccaa
    57541 tgggtaacaa cgatttatct tttgatgatt tcgatcattg ttccgctgtc tacttatttg
    57601 aatcgcaatt ttagtctcaa aaaactcttt ttagcttcaa atctgctttt cttggcaggt
    57661 ataatgatcg atttcttctc tcctaccttc atggtcctat tgtttggtcg attgctccaa
    57721 ggtgcagcga caggtatcgc tcttccgttg atgttccata ttatcttgac atttgccccc
    57781 ctcaatcgac gaggcgcgat gatgggtgtc ggtactttga caacggccat tgctccagca
    57841 attggcccca cttatggagg cattatgact tcacatttta catggaatca tatcttcctg
    57901 tttcttgtgc ccgttttgtt tctttctttg attatcggct ggtttgctat tcccgagatg
    57961 gcagtacaaa aaagtggtta tttggattgg ataagcgttt taggaatttg tcttttgttt
    58021 agtggaagtc taacattttt gagtacgttg ggaacagttt ccagctggat tgctttaatc
    58081 atcggcggta ttggctggtt ccttttttac tatcgaagta aaaaagtgga gcatccactg
    58141 atccgactgt ctattctttc aaataaaaca ttccgcttgt ttttgattgg cttcttagtt
    58201 tatcagtttt tattacttgg tgtatctttt gtcttgccga atttccttca gatcgttcaa
    58261 ggaagtagtc cttttgtcgc tggattagcg atgcttcccg gcgcagcggt tggtgctttg
    58321 ctttctcctt tttccgggaa aatgctggat caatatggtc cgaagaagcc aatttttgct
    58381 gggctgattc tttctttgat tggttggcta gcattattcc tactcatagg acacgcttca
    58441 gtgggtgtat tgattgcttg tcatgtgttt tatatgatcg gtatcggatt atcttacagc
    58501 aatatgatga ccaccggaat gaatgcactg aatgaagaac tacaaggaga cgggaacgca
    58561 atgttcaata ccttgcagca gttttctggc gctgtggcta cttcattagt agcggtcatt
    58621 atcaattacg tccagcatca tacttcccat aactatgaag tgtctactac attaggatca
    58681 aaagcagcat taggcgtctt gttgctgttg cttctcgtaa gctttgctcg attcgcctat
    58741 tatctgttct ttgctaaaaa agcgtagatt ccatatacgg caggtgttgc atctgccgtt
    58801 tttttgtgtg aaaatggttg tttgtaaaag gaggcttttt tatggaaaaa attgccatta
    58861 tcggtggcgg gatcattggt atgaccctag ccagttactt agatacatca aaattcaatg
    58921 ttgctttatt tgatgaaggg acaggacagg caactaaagc tagcgctggg attatctccc
    58981 cttggttgtc gaaacgcaga aacaaacaat ggtatcgtct ggctaaagac ggcgctgctt
    59041 ttttccctaa acttataaaa gatttccaac ttgatcaaac gatttacgca caatcaggga
    59101 cacttttgct tcgacctgaa aaagatttag ctgaattggc tgttcttgcc gagaaacgaa
    59161 aagaagaagc gccagaaatt ggaaacatcg aatggctttc acctgaacag acatctcaag
    59221 cacttccgtt attgaaacca gcagtttcac tgcgtatcag tggtggtggt cgtctggatg
    59281 gaaaagcata tttagaacat cttggtcagc gtttagcaca aaaacaaatg gagcagatcc
    59341 aggcaaaagt cactttgcat aagaagagcg attcttggct catcaaggga ccgtttggag
    59401 aatacacagc tgatcgtgta attttgacac ctggcccggc acttaagcct ttattacaag
    59461 aattaggcta tgctgcagat atacgtccgc aaaaagggca gctcttagca tttcagacat
    59521 cttataagat gagtcaagac tggcctgttg ctatgcttga cggagaagct gatttcattc
    59581 ctttcatgga tggaaagatc cttttaggtg ctacccatga aaacgatcaa ggctgggatt
    59641 tggctcctac tagcgaagct tataagggat tgactaagag tacagaacag ttcttgactg
    59701 atccagatca gataaaaaac tggccatacg agttccgtgt aggtacccgt gcttatacgt
    59761 cagatttttc cccatttttc ggcgtactgc cagatgatcc aagcttactg gctgctagcg
    59821 gtctaggctc ttctggcttg accacaggtc cttatatcgg ctatctatta gccaacttct
    59881 taaatactgg tcattggcct acggaagatt atcaaaagga catctccacc tatattacga
    59941 aaaatccatc atagaaaaac agctttttca agtaaggatc ccgagcgata ttgcgcatgg
    60001 attacttctt gaaaaagctg ttattttagt tcaatttctg aatcaaattc tccaaacttt
    60061 cttttgcttc atctggcaag agatcttttc ctatctgagc ttcaatgaat cgtaaacgaa
    60121 tatcaagtcg ttgtttcacc agatttttat aggacgtatc ctcaaaagaa acaggaaaat
    60181 ctggtatagg taaatagtgg atgtcttcaa atggaccaaa cgacttgaat tctgccgttt
    60241 gttgcacgat tctttcaacg attgacaatg tcgtttcagg tttgattttt ttatcatcga
    60301 aatatccagt attcaggaca tagcaggctg tttgctgttt caaaaacaac tctcgaaaag
    60361 cttgatagtc ttccctaaga ggatagacac ggaaaggatt agcaaatggt tcaatgacta
    60421 gctcatctag ctgtcttttt gtagtgatat tttccgcgtc tgatcgtttt gttgctaatg
    60481 ttgcaccaaa agacgctgct aaaactgggt cattgatctt gataattggc ggaagcgaat
    60541 catctttcat gatccaaaaa acagcatcga tcttttcgct aagatgatcg actcggtcgg
    60601 gtgtcgcata acgtgatttg actgtccgcc catttccgtt tcgtatatct cctgttacta
    60661 ggactttttc tcctttactt gtacatgtca cgcccacatt ctgacaagta aggaaagaag
    60721 aaatggccgg atcatcagac ggatagtctt gtgttttatc aaagtaagaa ggttccaagg
    60781 cagtagcaaa accatttttt cgagaaataa cgaaagcatc gtcatgcaag atcgaaacag
    60841 agtgaccttc cgtatgtttt gctaaggtaa tcgttgattt tccagaaccg gacaacccaa
    60901 atacagccat cgtataggtc tggtcattac tagcatattg tttcatccca ccgtggcagg
    60961 caataaagcc attgcgattt cccaatgccc aagcaagcgt caaagtcgct ttttttaatt
    61021 ctccaaagta acgtaatcct agcacagccg ctgtattatg gagagcatca aacaaaatga
    61081 gtccatttgg aaatgtttca tgtgtccatt cgggatcaca aaagatataa agatctccct
    61141 catcaaagga aacagacttt tgataagtct ctaagatctt cgaattcgct ggctgaaaat
    61201 tcagcaaata agaatacaaa ttgttctcaa atccttctgg aatcagcaaa tgactttgca
    61261 cagaaaattc ttcagatagg ccaacgatta cttttgtatg gtaaaactgg cgcttgcgac
    61321 tttgatacac agcttctctt aaaattttct cgtatttgct ttgttccttg tctaagtcct
    61381 caaagatccg ccgagcactt gctgttcttc ccacaatgct tccatcattg aatactagtg
    61441 tcctaacatc agctggtaaa tctagttctt cagcatgtga gattgttaaa tctgtgatga
    61501 tcgttcctgg actccctttt gctagttgat aagctgtctt cctatcaaaa acttcatgaa
    61561 cattattacc gtaaaatgtc gtttctacaa tcgatcgaat actggataac agtggatttc
    61621 cacttgtgat ttcgtttaat tcgagactct cttttgtact catggctcct cctcattccc
    61681 taaacaaaaa aacgttttct ttattataca ttattcgagt ttttatttgt actgctgcgc
    61741 tgtgggaagc aaacgagtta tttttcacac aaaaaaaccg agaacttgaa taaacaagtt
    61801 tctcggtttc atcattttcc ttttatcggc ttagtaccag ccgtttgcta accagaatgt
    61861 tttagcagca tcccatgaac cataacgaga tgttacatat tgttctgcta cacgttcttg
    61921 attggcagct gaatagtcgc cgtttaagta tgaagcatct aattgataac ggccgatgta
    61981 acgtccgtta gtagctgtgt atgaaccgcc tgattctttt tgtgcgatcc attcttttgc
    62041 agagcttgaa gttggcgctg ttgcagcagc tggggcagca ggagctactt caactgtttc
    62101 aacaggtgca acgtatgtat gttcttgcgt tgctgtttca gttgtagatg ctgtattttc
    62161 tgttgttttg ttttctgttg ttgctgaaga atcatttgaa gttgggattg ttaattgttc
    62221 accaacataa atgcggttga tgtttgcgat cgaatttttt tcagcaattg catcgatcat
    62281 tgagttgtct cctgcaaatt tttgtgagat cttagataat gaatcacctg attttactgt
    62341 ataaacttca tcagcgtgag catttgtagt tcctacaaac attgcagtag caccagcagc
    62401 aaaagttgta cctaaaacaa ttttcttaaa tgaattcata ttaaactcct ttttttctcc
    62461 gtttttt
//
LOCUS       DAFLVO010000007        62044 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.007, whole genome shotgun sequence.
ACCESSION   DAFLVO010000007 DAFLVO010000000
VERSION     DAFLVO010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 62044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62044
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.007"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            137..994
                     /locus_tag="L1U99_000463"
     CDS             137..994
                     /locus_tag="L1U99_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HBN1211034.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            1109..2029
                     /gene="pstC"
                     /locus_tag="L1U99_000464"
     CDS             1109..2029
                     /gene="pstC"
                     /locus_tag="L1U99_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBN1211035.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            2029..2913
                     /gene="pstA"
                     /locus_tag="L1U99_000465"
     CDS             2029..2913
                     /gene="pstA"
                     /locus_tag="L1U99_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBN1211036.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            2928..3734
                     /gene="pstB"
                     /locus_tag="L1U99_000466"
     CDS             2928..3734
                     /gene="pstB"
                     /locus_tag="L1U99_000466"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBN1211037.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3750..4508
                     /locus_tag="L1U99_000467"
     CDS             3750..4508
                     /locus_tag="L1U99_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBN1211038.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGINLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4521..5198
                     /gene="phoU"
                     /locus_tag="L1U99_000468"
     CDS             4521..5198
                     /gene="phoU"
                     /locus_tag="L1U99_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBN1211039.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5436..5735
                     /locus_tag="L1U99_000469"
     CDS             5436..5735
                     /locus_tag="L1U99_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211040.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKK"
     gene            5761..6468
                     /locus_tag="L1U99_000470"
     CDS             5761..6468
                     /locus_tag="L1U99_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBN1211041.1"
                     /translation="MSIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLL
                     NISILFVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYE
                     ELNYLTRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQV
                     GRDVIGSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVL
                     SIPISVLFFLTVRRLKR"
     gene            6465..7232
                     /locus_tag="L1U99_000471"
     CDS             6465..7232
                     /locus_tag="L1U99_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBN1211042.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7332..8900
                     /gene="liaX"
                     /locus_tag="L1U99_000472"
     CDS             7332..8900
                     /gene="liaX"
                     /locus_tag="L1U99_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HBN1211043.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEITQVQL
                     STTTGSIYLKDTDK"
     gene            9197..9517
                     /locus_tag="L1U99_000473"
     CDS             9197..9517
                     /locus_tag="L1U99_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HBN1211044.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            9517..9867
                     /locus_tag="L1U99_000474"
     CDS             9517..9867
                     /locus_tag="L1U99_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBN1211045.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            10034..10972
                     /locus_tag="L1U99_000475"
     CDS             10034..10972
                     /locus_tag="L1U99_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBN1211046.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            10987..11817
                     /locus_tag="L1U99_000476"
     CDS             10987..11817
                     /locus_tag="L1U99_000476"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBN1211047.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            11861..12886
                     /locus_tag="L1U99_000477"
     CDS             11861..12886
                     /locus_tag="L1U99_000477"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBN1211048.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            12901..13839
                     /gene="galU"
                     /locus_tag="L1U99_000478"
     CDS             12901..13839
                     /gene="galU"
                     /locus_tag="L1U99_000478"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBN1211049.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKKLEAEGSKIDHNPKGITEIKEEKKK"
     gene            13964..14404
                     /locus_tag="L1U99_000479"
     CDS             13964..14404
                     /locus_tag="L1U99_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBN1211050.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14407..15009
                     /locus_tag="L1U99_000480"
     CDS             14407..15009
                     /locus_tag="L1U99_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBN1211051.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDTKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(15077..16183)
                     /locus_tag="L1U99_000481"
     CDS             complement(15077..16183)
                     /locus_tag="L1U99_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBN1211052.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLASIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            16393..17394
                     /gene="ccpA"
                     /locus_tag="L1U99_000482"
     CDS             16393..17394
                     /gene="ccpA"
                     /locus_tag="L1U99_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HBN1211053.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(17697..20042)
                     /locus_tag="L1U99_000483"
     CDS             complement(17697..20042)
                     /locus_tag="L1U99_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBN1211054.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            20321..21223
                     /locus_tag="L1U99_000484"
     CDS             20321..21223
                     /locus_tag="L1U99_000484"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBN1211055.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            21436..23211
                     /locus_tag="L1U99_000485"
     CDS             21436..23211
                     /locus_tag="L1U99_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBN1211056.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYSSSKKMLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYSIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHAVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFAFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTAFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            23468..24685
                     /locus_tag="L1U99_000486"
     CDS             23468..24685
                     /locus_tag="L1U99_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBN1211057.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEENTLCSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFLNRLTPYALILIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKEALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
     gene            complement(25132..26718)
                     /locus_tag="L1U99_000487"
     CDS             complement(25132..26718)
                     /locus_tag="L1U99_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HBN1211058.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            26969..27193
                     /locus_tag="L1U99_000488"
     CDS             26969..27193
                     /locus_tag="L1U99_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HBN1211059.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            27335..29086
                     /locus_tag="L1U99_000489"
     CDS             27335..29086
                     /locus_tag="L1U99_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1211060.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLAPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAALLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGCSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQKLEAKIEGGEA"
     gene            29086..30870
                     /locus_tag="L1U99_000490"
     CDS             29086..30870
                     /locus_tag="L1U99_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1211061.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPTITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLTKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            31328..32179
                     /locus_tag="L1U99_000491"
     CDS             31328..32179
                     /locus_tag="L1U99_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1211062.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELYQVIQKKYKDTFGCVEKIADFLAEIFNYQMSTDEKMYLTIHIARL
                     VHENRCK"
     gene            32276..34162
                     /locus_tag="L1U99_000492"
     CDS             32276..34162
                     /locus_tag="L1U99_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1211063.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGVVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNPGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(34203..35105)
                     /locus_tag="L1U99_000493"
     CDS             complement(34203..35105)
                     /locus_tag="L1U99_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBN1211064.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            35335..36738
                     /locus_tag="L1U99_000494"
     CDS             35335..36738
                     /locus_tag="L1U99_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBN1211065.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMNELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            36735..38171
                     /locus_tag="L1U99_000495"
     CDS             36735..38171
                     /locus_tag="L1U99_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBN1211066.1"
                     /translation="MMGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFP
                     VITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGD
                     EKEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENL
                     CRVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASA
                     IATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPA
                     YALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFAS
                     VKNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDY
                     RIDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGN
                     GTLARSKKKSFNWYKKVIDSNGENLSND"
     gene            38316..39242
                     /gene="trxB"
                     /locus_tag="L1U99_000496"
     CDS             38316..39242
                     /gene="trxB"
                     /locus_tag="L1U99_000496"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBN1211067.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            39455..41182
                     /locus_tag="L1U99_000497"
     CDS             39455..41182
                     /locus_tag="L1U99_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBN1211068.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     TIIQKMTEE"
     gene            41198..41548
                     /locus_tag="L1U99_000498"
     CDS             41198..41548
                     /locus_tag="L1U99_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBN1211069.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAIIQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(41632..42492)
                     /locus_tag="L1U99_000499"
     CDS             complement(41632..42492)
                     /locus_tag="L1U99_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBN1211070.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPSVEFNLFRRT
                     FVTDEKTLMQALQDALEEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            42584..43012
                     /locus_tag="L1U99_000500"
     CDS             42584..43012
                     /locus_tag="L1U99_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBN1211071.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            43174..43350
                     /locus_tag="L1U99_000501"
     CDS             43174..43350
                     /locus_tag="L1U99_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBN1211072.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            43377..43823
                     /locus_tag="L1U99_000502"
     CDS             43377..43823
                     /locus_tag="L1U99_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBN1211073.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(43979..45358)
                     /gene="brnQ"
                     /locus_tag="L1U99_000503"
     CDS             complement(43979..45358)
                     /gene="brnQ"
                     /locus_tag="L1U99_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBN1211074.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            46064..47035
                     /locus_tag="L1U99_000504"
     CDS             46064..47035
                     /locus_tag="L1U99_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBN1211075.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            47059..49251
                     /locus_tag="L1U99_000505"
     CDS             47059..49251
                     /locus_tag="L1U99_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBN1211076.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            49268..49744
                     /gene="ybeY"
                     /locus_tag="L1U99_000506"
     CDS             49268..49744
                     /gene="ybeY"
                     /locus_tag="L1U99_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBN1211077.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            49728..50123
                     /locus_tag="L1U99_000507"
     CDS             49728..50123
                     /locus_tag="L1U99_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HBN1211078.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            50138..51037
                     /gene="era"
                     /locus_tag="L1U99_000508"
     CDS             50138..51037
                     /gene="era"
                     /locus_tag="L1U99_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBN1211079.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            51180..51992
                     /gene="recO"
                     /locus_tag="L1U99_000509"
     CDS             51180..51992
                     /gene="recO"
                     /locus_tag="L1U99_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBN1211080.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKSGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            52376..53293
                     /gene="glyQ"
                     /locus_tag="L1U99_000510"
     CDS             52376..53293
                     /gene="glyQ"
                     /locus_tag="L1U99_000510"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBN1211081.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            53295..55370
                     /locus_tag="L1U99_000511"
     CDS             53295..55370
                     /locus_tag="L1U99_000511"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBN1211082.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEIIPFEILDVKTDRASRGHRFLGEDVTFTHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            55760..56539
                     /locus_tag="L1U99_000512"
     CDS             55760..56539
                     /locus_tag="L1U99_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211083.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKNFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
     gene            56585..57529
                     /locus_tag="L1U99_000513"
     CDS             56585..57529
                     /locus_tag="L1U99_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBN1211084.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTLQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            57545..58324
                     /locus_tag="L1U99_000514"
     CDS             57545..58324
                     /locus_tag="L1U99_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HBN1211085.1"
                     /translation="MEETISLKEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDALGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            58336..59034
                     /locus_tag="L1U99_000515"
     CDS             58336..59034
                     /locus_tag="L1U99_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HBN1211086.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAR
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILDEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLNKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            59062..59826
                     /locus_tag="L1U99_000516"
     CDS             59062..59826
                     /locus_tag="L1U99_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBN1211087.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMTASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPDYEEVKKKKFGLF"
     gene            59840..61657
                     /locus_tag="L1U99_000517"
     CDS             59840..61657
                     /locus_tag="L1U99_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBN1211088.1"
                     /translation="MFILTRRRKIATLVFVDSLLLIAANIAAAKFMKPFVSIPMDLIL
                     ISIGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFSSLSASAASSILILLFINRRYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYVSADSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIHVVGFVDDDPNKRNTYLSGKKVLGALKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESARVKVNTMPSIEELASGKISVSKLKTIDVVDLLGRDEVKLDIESI
                     KDQITDKVILVTGAGGSIGSEICRQIIQFNPAKLLLLGHGENSIYLIDRELRTHHQNC
                     PTEIVPIIADIQDREKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAQGGPITVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSIQKVMDFVKSLPQDDEQLAKDIVTFANASNR"
     gene            61711..>62044
                     /locus_tag="L1U99_000518"
     CDS             61711..>62044
                     /locus_tag="L1U99_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylate--amine ligase"
                     /protein_id="HBN1211089.1"
                     /translation="MNAFKTALNNNEMEGKIIGADCSELAPALYMCDEKIVLPKVSES
                     NYIEELIKVIKFFEIKLIVPTIDTELSTLSRNKKYIENETDSVVLVSSEKVIDICENK
                     ILTSAFFEQ"
BASE COUNT        20288 a        11095 c        13131 g        17530 t
ORIGIN      
        1 agcatagaaa cttttaatga gatagttttt tttacaatta tgagaattta ttttgttatt
       61 taatgatttt gattcgtttt catcaagtaa tgaaaatgat aaaataaaca tactttagga
      121 ttaaaggaga tttctaatga aaaaacttaa attattctta ccaataatag gattagccat
      181 tcttttatca ggctgttcaa agtggattga tcgaggagaa tccattacgg ctgttggctc
      241 ttctgcttta cagcctttag tagaaacagt tgctgaaact taccagacag aaaatcctgg
      301 aaaattcatc aatgtacaag ggggcggaag cggaactggt ttgtctcaag tacagtcagg
      361 agcagtcgac atcggaaact ctgatttgtt tgcggaagaa aaatcgggga tcgatgcctc
      421 agcattagtc gatcatcgag tagcagttgt tgggatcact cctattgtga acaaggatat
      481 tggcgtaaaa gacatcagta tggaaaacct gaaaaaacta tttacaggcg agatcaaaaa
      541 ctggagtgaa gtcggtggaa aagatcagcc agtagttata ttgaaccgcg cttcaggaag
      601 cggaacccgt agcacgtttg aaaaatgggt attggacgga gaaacagctg ttcaggcaca
      661 agaacaagat tcaagcggaa tggtgcgcca gatcgttgcc gacacacccg gtgcaatcag
      721 ctatgttgct ttttcttatg tttccgatga tgtagatacg ttgaatgtta acggtgtaga
      781 accgacagat gaaaatgtga caacgaacaa atggacgatt tgggcatatg agcatatgta
      841 cacaagagat catccaaaaa aactgacaaa agaattttta gactatatct tatctgatga
      901 agtacaagat aacatcgttg gagaactagg ttatatccct gtttctcata tgaaagtcga
      961 acgtgattgg caaggaaata tcgttaaaga gtaatcttta cacaaaattt acaaacttag
     1021 ctaaactttt acatgttatt aaaaccaaat tgatgttcaa tttgtacact gagtgagtat
     1081 gttaaacctg attaaggggg agtcatctgt ggaagatgtg aaaaaagtat tattaacaaa
     1141 atcaaaacgt tcaaaaatgg aacagcgtgg aaaattcatc agttttttat gtatcgcgct
     1201 gatcgtgttg gttgtattat ctatttttta ttttgtagct agtaaaggat tggccacctt
     1261 ttttactgat aagatcaatg tatttgattt tctgtttggt acagattgga atccaagcca
     1321 aatcggagca aatgggaaac caatggtagg ggcattgcct atgatcacag gttcgtttat
     1381 tgtgaccttt ttatctgcta tcgttgccac gccatttgcc attggtgcag cagtattcat
     1441 gacggagatc tctcctaaaa acggaacgaa gatcttacag ccggtcatcg agctgcttgt
     1501 aggtattcct tctgtcgttt atggttttat cggtttatca gttatcgtgc cttttgtcag
     1561 aagtattttt ggcgggacag ggtttggtat cttagctggt acatttgtgt tgttcgttat
     1621 gatcttgccg actgtcacaa cgatgactgt tgatgcatta aaggcagtgc cacggcacta
     1681 tcgggaagct tcattagcgc ttggtgccac aagatggcaa acaatctaca aagtcgtgct
     1741 acgagcagcc gtgcccggga ttttaacagc agtcgttttt ggtatggctc gtgcgtttgg
     1801 tgaagcctta gctatccaaa tggtcatcgg taatgcagca ttgatgccaa caggacttac
     1861 tactcctgct tctacattga cgtccatctt aacaatggga atcggaaata caatcatggg
     1921 aacagttgaa aataatgtgt tatggtcatt agcgctgatc ttgctattga tgtcattatt
     1981 ctttaatatc gtgatccgta tgattgggaa gaaaggagag ctgaaataat gaacgcaaaa
     2041 cgctcagata aaattgctac aggtgtttta tatatagttt cggggatcat cgtattgatt
     2101 ttagcagctt tactacttta tatcttagtt cggggaatac cgcatatttc atggtccttc
     2161 ttgaccgaac cttccaaagc ctaccaagaa ggcggtggaa tcgggatcca gctatttaac
     2221 tcgatttatt tgcttttgat cacgatgatc atcagttttc ctatttcttt aggtgcgggt
     2281 atctatcttt cagaatatgc tggaaaaaac tggctaacag atgtgattcg cacgtcgatt
     2341 gaaatcttga gctcgttgcc ttctgtcgtt gtcggtttat tcggtttctt ggttttcgtt
     2401 attcaattcc agtatggttt ctcgattatt tctggtgcat tggctttgac tgtattcaac
     2461 ttgcctcttt tgactagaac agttgaggag tctttacaag cggtccatta cacacaacga
     2521 gaagcaggat tggccttagg tttgtcacgc tgggaaacag tgataaaagt ggtggttcca
     2581 gaagcgacac cagggatttt gactggtgtg atcctaagtt ctggaagaat ttttggtgaa
     2641 gcagctgcat tgatctatac ggctggacaa agtgcacctg cgttagattt tacgaactgg
     2701 aatccattaa gtgtttcaag cccgatcagc attttccgtc aagctgaaac attagctgtc
     2761 catatttgga agatcaatac agaaggcacg atgcctgatg gtgtttctgt ttcggctggc
     2821 gcttctgccg tgttgatcat tgctgtttta ctgttcaact tcggcgctcg tgcgattggc
     2881 aaacgattat accgaaaaat gacttcagcc taaggagaag aagcaaaatg aaaaaatata
     2941 actggaatga aacaaatgtc atcaccatgc caaaagagaa agaagtagca ctatatacgg
     3001 atgatctaca tgtctggtat ggcgacaatg aagcaatcaa aggagtggat ctggaatttg
     3061 aaaaaaataa gatcactgca ctgattggtc cttccggctg cggaaaatct acgtatcttc
     3121 gttcgttgaa tcgaatgaat gatgggatcg ctaatacgaa aatcactggg aaaatcatgt
     3181 atcaaggcgt agatattaat gcgcctcaag tggatgttta tgagatgcgc aaacggattg
     3241 gcatggtttt tcaacgtcct aatccgttca gcaagtcgat ttatgacaat attacatttg
     3301 ctttgaaaca gcacggcgaa aaaaacaaaa agaaattaga tgaaatcgtt gaaacaagct
     3361 tgaaacaagc tgccttgtgg gaccaagtaa aagacagctt ggacaaaagt gccttggctt
     3421 tatctggcgg gcaacagcaa cgtttatgta ttgctcgtgc gatcgcgatg aaacctgata
     3481 tcttgctgct agacgagccg gcaagtgctt tggaccctat ttcgacagga acggttgaag
     3541 aaacacttgt aaacttgaaa gaagactata cgatcatcat cgtgacgcat aacatgcaac
     3601 aagcagctcg tatcagcgac tatactgcct ttttctatct aggaaaagta atggaatatg
     3661 acaaaactaa caagatattt accagaccaa aaattcaggc aaccgaagat tatgtgtccg
     3721 gtcattttgg ttaagacgga ggcctcaaca tgacaaaaga aattatttca tctaaagatc
     3781 ttcatctgta ttatggaaag aaagaagcac taaaagggat caatctaagt ttcaatcaag
     3841 gggaaatcac tgcgatgatc ggtccttctg gttgcgggaa atccacttat ctgcgttctt
     3901 tgaaccggat gaatgacctg attccgaatg taacgatcac cggaagtgtt ttatataaag
     3961 acaaagacat ctatggtcca aaaacagatg ttgttgaact aagaaaagaa atcggcatgg
     4021 tattccagca gccaaaccca tttccttttt ctatctatga aaatgtcatc tatggattga
     4081 aattaaaagg ggaaaaagat aaaaaagtcc ttgatcaagt agttgaagaa agcctgaagg
     4141 cagcgtctgt ttgggatgat gtgaaagaca aattgcataa aagtgcttta tctttatccg
     4201 gtgggcagca gcagcgtgta tgtatcgcac gtgttttggc agttaatccg gaaatcatct
     4261 tattggatga accaacaagt gcgcttgatc ctgtttctac tgggaaaatc gaaagtatgc
     4321 tgttagaatt aagagagcgg tatacgatga tcatcgtgac ccataatatg tctcaagctt
     4381 cacgtatttc agataagacg gcattctttt tagatggtca cttgatcgaa tacaacgata
     4441 cgaagaagat attcatgaat ccagaaaaac aagagacaga agattatatt tcaggtcgat
     4501 ttggataagg aggaaacgga atgctacgta cacaatttga agaagaattg ctgaatctcc
     4561 ataatcagtt ctacgaaatg gggatgatgg tgagcagcgc cgtgcacaag tcagttcgtg
     4621 catacatcaa acacgataaa atcttagccc aagaagttat cgaaaacgat ataaatatca
     4681 ataacatgga aacacgcttg gagaagaaaa gttttgaaat gatcgcattg caacagccag
     4741 ttacaactga tttgcgtatg atcattacgg tcatgaaagc tagctcggat ttagaacgta
     4801 tggccgatca tgcggtgtct gttgctaaat ccacgattcg cgtaaaaggg cagacgagaa
     4861 taccggaaat cgaaaaagag atctccgata tgtccgatta tgtgaaaaaa atggtggaca
     4921 acgtcctagt tgcttatgtc aaaacagacg aaaaagacgc acgtacgatc gccaatatgg
     4981 atcaaagagt caatgactat ttcaatcgaa tctataatgc aacaatcaaa aatatgcagg
     5041 aaaatcctga gacagtcatc agtggaacag actacttgaa tgttgccagt tatctagaac
     5101 ggatcggaga ctatgtgaca aacatctgtg aatggatcgt ctacttggct acagggaaaa
     5161 tcactgagtt aaatacgaac cacaatgaga ttttctaaac tgaagctgtg attatgccgt
     5221 ttgtttagga aaagaggttg tgaaatcagc ggttgtgaaa aagctgttct gcatcaagta
     5281 ataagaacag tcaaacaaaa aatagctcct catatttttc gtttggctgg acttattacc
     5341 gcagatgcaa gcttttgaac accgtttatt cgggaaaggg tttgtgacaa aacatgtcac
     5401 aaaccctttt catcatttca tagaaaggat aaagaatgca aaaaaaaatt agcatcatca
     5461 ctatattttt tatttgtgtg cttacttcat gggttattca gcatcaagct gctttatatg
     5521 aagtacctgt catcgagatc gaaaaagtac gaataaaaga ggatcatcaa ttgattacag
     5581 gaagactgat gaacacggat caaaaaggag aatcgattta tttatcggtt ccttatcaaa
     5641 aaaatcaaat agaaacagca aatataaaag cgagacaaat gtatctagtc caaatgcatg
     5701 gagatgaatg gcagctagta gcaaaaaaaa aatgatggct ggcttttctt cttcacaagt
     5761 atctccattg gcgccatgtt gcttattggc ggaaaacagg gtctatttgc tttaggaagt
     5821 ctcatcatca atatcgtttt acttttactt ttgttgctca tctttactaa aacagaaggg
     5881 atttctctat taaatatatc tatcctgttc gtcgttatag ggatgattat tagcatattg
     5941 gctttagatg gatggaatag aagcagtata atcaaaattt cagctgcagt tacgagtgtt
     6001 tttttagcat tttttatttg tcttttgaca atgaatcatt ggaaagacca aggactgcgc
     6061 tatgaggaac tgaattatct gacacgaccg tatcgttctg tttttctttc tagcgtactg
     6121 attggaacag ctggaggaac actcgatacc gttatcacag tcattgcgac attagaagaa
     6181 ttgactaagc gacaaccaga aataacagcg aaacagttat ggctttcagg aaggcaagtg
     6241 ggtcgagatg tgattggctc gatgaccaat atccttttgt tcgtctatat cagtgggtca
     6301 gttccatcgc ttcttttata tttaggaaat caatggtcgt tcaaagaaac gatagaacag
     6361 catttatcat tggaattttt acgcgtcatt gctggcagct taggaatagt attatcgatc
     6421 cctatctcgg tcctcttttt tctgactgta aggaggctga aacgatgaat gtacttatta
     6481 tacttgttgg gattttagca atcagcgtgc tacttattgg cggtacgcaa ggtatgtata
     6541 ttcttttagg cttattcatc aatttaggga tctttttcct gttgttattc ggttatcatc
     6601 agaagtggcc gatactggca ttgtcggtca taggattttt attgattgct gtggttatct
     6661 tattttttat caacggttat aatctaaaaa tgcgtgcagc ttttgtgagt atactgatct
     6721 ttttattttg tttcctacta ttgcttccta tcactgattt tttagcgatc caaggtttta
     6781 catcggtaga actagaagaa ttatctggct tagataagac tttagcgatt gattttagat
     6841 tacttacgag atcgttgctt ctgattagtc ttagtggtgc tgttttagat gctagtgtag
     6901 caatttctag tgggacattc gaagtatatc aggcaaatcc gcaattatct ttttaccaat
     6961 tgcgccattc tagtttcgct attgctaaaa aaatattggc gtcaacagta atgacacttc
     7021 tttttgcatt catgggaagt tctttagcgt tgatcctctg gtttattgat ttagacattc
     7081 cttttcagca agtgatcaat gaaaaatcat ttgttctaga atatacgatg gctattctta
     7141 ccacattgtc tgcactactt gttcttcctt taacctgcgt gactacagca tatctcttta
     7201 caaaaaagaa agaacaactc aagatggagt aaaagttaca acttaagtcc tatgacattt
     7261 ttactgaatc agtgcataat atggatgtaa ggaaaagctt gcaaacaatt ttgcttaagg
     7321 aggcaatttc catgaaagaa agagaacgta ttttagattt agtgaaaaaa ggaatccttt
     7381 cgactgaaga aggcttagat ttattagaaa gcatggcaac tgaaaaagac gaaaagcaaa
     7441 taaaaaaaga agcagacaag gtaactgcta gtcataaaga aaaagatcag gcaagtcaat
     7501 tgatcgataa acttgaaaac ggcgaagaag aaatttctga gccagttgat ccaaaggaaa
     7561 gagaaaggca agatcaagaa aacttagaaa agatcttaga tgaactagca actgaagcga
     7621 ataaaacttc ggcgcgtcta gatgaagtaa atgctcaatt cgctgacaat aaggcagcac
     7681 gcaatgagaa acaggaagca ttgatgcagc tgaatacaaa agaagaatta ggcgagttga
     7741 cagaagaaga attagcacag cgtcagacgt tagaagcaga aatcaaagaa ttagaagcta
     7801 gtggcgatac actgttagaa gaacaattga aattagaagc agaattaaaa gatatccgta
     7861 agaatcaatg gtctgagaaa aaagaaacgt ttactgataa gtttgaattg ccagatgatt
     7921 ggaaagatca agcaacagat acactgaatc aagtaggcga aaaaatgtca gaagctggat
     7981 cacagttagg caaattcttg aagaaaacat tccaaactgt ttcagaaaca gtgaatgaca
     8041 acatggaatg gaaagatgtc agcttacgtg tccctgggat tgcgacaacg aaatttgagc
     8101 atgaatttta ctatgaagct cctgcagcaa gtatccttga tatcaaggca gcaaacggaa
     8161 acgtgacgtt aaaaacgtgg gacagcaacg atgtgaaagt tgaagctaag atcaaacttt
     8221 acggaaaaat gggtgctgaa ccatttgaag cattctctga acggagccag attgaggtta
     8281 atgaagatca tatctccttc caaattccaa ataaacgtgt gcgtgcagac cttgttttct
     8341 acttacctaa acgagtatac gaccacgcag ctattaaact tctaaatggc aacatcatga
     8401 ttgaaacatt ggaagctaaa gatatttata caaaatctac gaatggtaac atcatcgtgg
     8461 accaattaac tgcaacgatg ctggaagtag aaggtgtaaa cggcaatatc gatattcgaa
     8521 acgggaacat cttagattct attatcgaaa cagtaaatgg tacagtgaca tttggtgcga
     8581 cagcagaaaa cctttctgtg tctttggtaa atggtgatgt acgtcttacg attaaagaag
     8641 ataatttgaa aaaagtagaa gcaagttcag tgaacggaaa tgtcaaagtc gctttaccag
     8701 atggcatcgg tttggaagga catgctaaaa caagtcttgg aagtatcaac agccgtctgt
     8761 ccaattacga agtagttcgt gagaaaaaag aacggacaaa ccaaatgttg caattccgtc
     8821 gtgtttcaga tggtgaaatc acgcaagtgc aactttcaac gacaacagga agtatctatt
     8881 taaaagatac agataaataa agaggttgtg aaagagatgt tcagccttga gcaataagaa
     8941 gcgattttgt aaaatagctt cccctatttt acaaaattgt gccttattgc cgataggcta
     9001 tctcttgaac accgtttacc aagagattat gaacctgcca attatcgccg agtcacaagg
     9061 aataatttca gaaaaagctc gtcacgtttt atgaatatgg taatttgtga ccgagaattt
     9121 tgcagaaaga caccgattaa gaagaaggtt gtcacaacga ttttcttcat ttaaaatagt
     9181 agaacagagg tgagacatga tgaaaaaaaa gttgacaaaa tccaataaaa atgttgtttt
     9241 gacagggact ttagcaggaa taggagaata catcgggatt gatccgactg ttatccgtgt
     9301 gctttatgta ttcctgagct tagttgcttt tggaagtcca atcattttat acattttatt
     9361 agctttgatt atcccatctg cgcgttctgc acgaacaaac tatggacata acaatgcata
     9421 ttatgaaaaa aacaattatc gtgaacaaac tcgtgaacaa acaaaaaaac gcaaagaagc
     9481 ggaaaaaatc gatgatgacg aatggagtga cttttaatgt cgtactttca acgtatttta
     9541 gttaatacgt taacattcat atcattggct gttctttttc ctgcgatggt ccatgtgagc
     9601 agtatttgga cggccgttct tgccagcttc gtattgtctg tgttgaatat gtttgtcaaa
     9661 ccgattttga cgatactgtc cctgcccttt acattagtca cattgggatt gtttacgttt
     9721 gttatcaatg cagcgattct taaaatgacc tccttttttg tgggagcaga acattttagt
     9781 ttttcttcat tcggtgcagc gttgttagta gctatcttga tgtcgcttgt caatgtaatt
     9841 gtcagtgaac ataacagtag aaaataaaag aaagctgtgc cgaactatcg gcgcagtttt
     9901 tttatttaga atcaggaatg cgttttctat tacattggta attaaataaa aacgtttttt
     9961 ttaattggta gtacttttgg ctagacaatg ataaaatgat agagaacact ctaatagaaa
    10021 tgaggtagca tgaatgtcag aagttgtaaa agttagccaa ttagtgaaaa aattatcttt
    10081 ggaaatcgtg acaggcgacg agaaaagctt agaccgtgtc atcgtaactg gggacatctc
    10141 acgcccagga ctagagttga ctggttattt taattattat tcccataatc gtttacagct
    10201 atttggcagt aaagaaatca gttttgcgga acggatgatc ccagaagagc gtttgatcat
    10261 catgagaaga ttatgtagtg aagatatgcc cgcatttatt atttcaagag gattaccggc
    10321 tccagaagaa atgatccagg cagcaaatga aaatgggata gctgtactgc gttctcccat
    10381 ctcaacttct cgtttattag gagaattatc cagttattta gatggtcgcc ttgcccctcg
    10441 aacaagtgtc cacggtgttt tagtggatgt ttacggatta ggtgtactga ttcaaggtga
    10501 cagtgggata ggaaaaagtg aaacagcgtt ggagttgatc aaacgcggtc atcgattgat
    10561 cgcagacgat cgagtagatg tttatcagca agatgaatta acggtgatcg gagaaccgcc
    10621 taaaatcctg gaacatctaa ttgaaatccg aggaatcggg atcattgatg taatgaatct
    10681 ttttggtgcg agtgcggtac gtggctctat gcaagtccag ttggctgttt atctggaagc
    10741 atgggcaaaa gataagaaat acgaccgtct gggctctgaa gacacgaccg ttgaaatcgc
    10801 ggaagtgggc attccacaaa taaaaatccc tgtcaaaaca ggacgaaacg ttgcaatcat
    10861 cattgaagta gccgcgatga atttccgtgc acgtacaatg ggctttgacg caacgaaaac
    10921 atttgaagaa agattaagtc gcttgattga agaaaactca ggcaacgact agcaaggagt
    10981 gacaatatgt tagcacaaat caatcgagtt gcttttgagc ttgtagggat tcctatctac
    11041 tggtatgcat tgatcatcgt atcaggtatc attatcgcca tgtggcttag cagcagagag
    11101 gctgttcggg taggattaaa agcagatgat gtgacagatt ttatgttgtg gggattgcct
    11161 atctccatta ttggtgctcg cttatattat gttttatttg atcttcccca gtatatagct
    11221 gatccaatcc aaatattcaa tatccgttca ggaggcttag ctatttatgg cggactgatt
    11281 gcaggcgcga tcacgctgta tttttttact aaatatcatt ttatttcttt gtggactttt
    11341 ttagatatcg ctgcaccaag tgtattatta gcacaggcaa tcggtcgttg gggaaatttc
    11401 atgaaccacg aagcatatgg accagacacg acgcgaagct tcttagaaag tctgcattta
    11461 ccgcaattca tcattgataa tatgtatatc gaagggatct atcgtcaacc aacatttctt
    11521 tatgaatcac tttggagttt gattggattt attttgcttt tgtttttacg aaagaaacca
    11581 caccttttga aaaaaggcga agtcctttta tgttatctaa tgtggtatag tttcgggcgt
    11641 ttctttattg aaggattacg tacagacagt ctttactttt taggtgtgat ccgtatttct
    11701 caattattat ctgctgtgtt atttgtcggt acattgattc tatttatttg gcgcagaaaa
    11761 aaaggaaatt taccggatta tgaccgctca ttaggaaaaa atcaacaaat tatctgattt
    11821 ttagagcgtt aaaaatgaaa aaaatttcag gagtggtaaa atgaattata gagtagcggt
    11881 tttaggacca ggctcttggg gtactgcttt ggcacaagtc ctcgccgaaa acggacatga
    11941 cgttcggatt tggggacatc gtgcttcaca agtagaagaa atcaacaccc aacacacgaa
    12001 tcaacgttat ttaccagatc attatctacc cgattccatc caagcattca ccaatatgga
    12061 agatgcagta aaagacgcag atgcggtgct attcgtcatt ccaacgaaag caatacgttc
    12121 tgttgcaaaa gaactagtgc ctaaattgaa tacaaagcca gtgatcatcc atgcaagtaa
    12181 aggattagaa cagggaacac ataaaaggat ctctgacatc ttgttagagg aaatcccagc
    12241 agaaaaaaga aaagctgttg ttgttctttc tggaccaagc catgcagaag aagtagcgaa
    12301 acatgacatc actacgatca cagctgcaag tacagatgca aaagcagcaa aatatgtaca
    12361 agagctgttc atgaataatt attttcggat ctataccaat cctgatgtga tcggtgtaga
    12421 gatgggggca gctttgaaaa atattattgc tattggtgct ggcgctattc acggcttagg
    12481 gtttggcgat aatgcaaagg cagcaatcat gacgcgcgga ttagctgaga tcagccgttt
    12541 aggtgtagca atgggtgcca acccgctgac ctttatcgga ttaagcggag taggcgatct
    12601 agtcgttact tgcacaagtg ttcattctag gaactggcgc gcaggcaact tgttaggaca
    12661 agggcagccc ctagaagagg tgctagccaa tatgggaatg gtcgttgaag gtgtgaatac
    12721 tactcaagca gcgatggaac tagcccaaat aatggaaatc gaaatgccca tcactcaaac
    12781 aatctatgaa gtgctgtatg aacaaaaaga aatcaaaaca gccgcaaaag aaatcatgtt
    12841 acgtgatggg aaaaaagaaa atgaattctc attaacaatt ttttgaagga gcgaatgtat
    12901 atgaaagtca aaaaagcagt tattccagcg gcaggattag gaacaagatt tttaccagca
    12961 acaaaagcta tggcaaagga aatgttgcca attgttgata aaccaacaat ccagttcatc
    13021 gttgaagaag cgttgaaatc aggaatcgaa gacatcttga tcgttacagg aaaagctaaa
    13081 cgaccaatcg aagatcactt tgattcaaat attgaattag aaacaaacct aagtgaaaaa
    13141 ggaaagaccg aattattgaa attagtagaa gaaacgacag atgtcaactt gcatttcatc
    13201 cgtcaatctc atccaaaggg tttaggacat gccgttcttc aagcaagagc ctttattgga
    13261 aatgaaccgt ttgtcgttat gctaggcgat gatatcatgg aagatgaagt accattgaca
    13321 cagcaattaa tcgatgatta cgaacgtact catgcttcta cgatcgccgt tatgcaagtt
    13381 cctcatgatg aaacttcaaa atacggaatt atcaatccag gagaagtatt ggaagatggg
    13441 ttatacaatg tcaaaaactt tgttgaaaaa ccagatccaa gcaaagcacc aagtgattta
    13501 gctattattg gacgttactt attgactcca gaaatttttg atgtattgtc cgagcaacaa
    13561 ccaggagccg gaaatgaaat ccaactaact gacgcaatcg atacattgaa taaaacacaa
    13621 cgcgtatttg cccgtaaatt cacaggtaaa cgttacgatg tcggtgacaa atttggtttt
    13681 atgaaaacaa gtattgaata tggtctaaca catccagaag taggtgcacc tttacgtgag
    13741 tatatcctgt ctttaggtaa aaaattagaa gcagaaggaa gcaagatcga tcataatcca
    13801 aaaggaataa cagaaatcaa agaagaaaag aaaaaataac ccttttttct aacgagcttc
    13861 agctgctaat tgaataaaaa gtagttgaag ctcgttttta tttgtttaaa aaacacgaaa
    13921 atgctatcct tatagaaaag agagacaaga agggagtttg atcatgtcag gaggagaaat
    13981 tgcaggattg atcgcagcaa tcgcctttgc gatacttgtc gtttttatcg ttcgtgtgtt
    14041 gttgcaagtt tctaaaactt tagaaaaagt agatcagact gtagcagaag caaatacgac
    14101 gatcgaaatc gtcacaaaag acgtagatct tttgtctaga caagtagaag gcttgctggt
    14161 caaaagtaat gaactgctct tggatatcaa tggaaaagtc gcaacgatcg atccattgtt
    14221 cacagcagtt gctgatttaa gtgaaagtgt atcagaactt aatcattcta gtaaaaacat
    14281 cgcgacgaaa gtcggcggaa tcggtaaaac gacagctaaa gcgacggttg ccggaaaagt
    14341 cggtgggaca gcgatgaaat tttttaaaaa caaaaaacat actgaaacga caggaggaaa
    14401 ataaaaatgg ctaaaaaagg tggattttta ttaggtgcag tagtcggagg aacagccgca
    14461 gcaatcgccg cgttattgtt agcaccaaaa tctggtaaag aacttcggga tgaattagct
    14521 gcccaagcgg atgatttgat ggatatggct tcagattaca cagatatggc gaaagaaaaa
    14581 tcgactgagt taacaggtat tgcaaaagaa aaagcgcaag atctttctca acaagcaggt
    14641 gatctagcag gtagtgtcaa acaaaaagta agtgaatcag cagatgaagc aggaagtgaa
    14701 tctgacgata tcttgttaaa tcttaaagaa caatcagctg acttatctaa tcgtttcaaa
    14761 aaaacggcag aagatatgaa aaaacctgca gatgaattag gaagtattgc taaagatact
    14821 tcagaagata tcatgattga tgtaaaagac gctgctggta aagcaggaga tactgtcaat
    14881 gaaggaatgt cagaagcaaa accagttgca gatgacacaa aagaaatgat gaaaatggca
    14941 aaagaagatg cgaaagaagc taaaaaagaa ataaaagata caatgacaga ttcatctaca
    15001 aatcactaaa atcactaaaa tcacaaattt atagaataaa aaggtgggag cggactagct
    15061 ctcacctttt ttactcttat ttttctaaaa ctagtaattc ttttggtgta gtcgtgaatg
    15121 gcacacagcc atcgcttgtc acatatacac agtcttcgat acgtacccct actttttcag
    15181 gaatatagat tcctggttca agagagaagc acatcccttc ttcgattact aagtcatttc
    15241 cttctacaag ggaagggaat tcgtggacgg ttgttccgat cccgtgacct aaacggtgat
    15301 tgaaatattc gccgtagcca tagctgttga tcacgtttcg tgcgatttga tcaagttcac
    15361 ctgctgtcac acctggacgg acggcttctt gtgcggcaag ctgtgcttca agagtgatgt
    15421 tgtatatttt ttcttggaag tcggttggtt tttgataagc aattgtacga gtagcatcac
    15481 tgcaatagcc attccaaaca acgccaagat cgaataacac aagttcattc ggtgaaatct
    15541 tcgtgtttcc tggtgtacca tgagggcttg cagcatttgc tcctgcaagg actaatgtgt
    15601 cgaaagacat ttgtgaaaca ccttgttttt tcaattggta ttcgatttct gcaatgatcg
    15661 cttgttcagt cacgccttct ttcactgctt taaagccaat ctcaaatgca acatcggccc
    15721 atttaccagc ttcgatcagt ttgtcttttt cctctagagt tttgatcagt tgtagacgtt
    15781 ggatgatgga agctagatca gtgtaagaat ccgttcccgt caagatatca gagatagcat
    15841 cgaagcgctc gacagtcaag gcgttctttt caatccctac attgccaggc tgaccatagc
    15901 gagcacgaag ttcttttccg atgatctccc aagggttttc gctgtctaaa tagccacgga
    15961 catcatacgc ccaactactg ttttgagcat cttcaacttc caaagcagga gtgaaaagga
    16021 aaggatcttg ttcaagaggg ataaaaagag ctagtacacg ctcatgagga tcactttcgt
    16081 atccggaaaa gtaagcgatg tggccagggt cgctgatata agccaattcg acttggtgtt
    16141 gtgccatcca ttgacgtagt tcattgattt ttacgttatt catttggcaa cctactttct
    16201 aaattaattt tgtattcaat aattgtacca ctgatttatt aaaagaccaa cgttctaaaa
    16261 actgaaaaaa gtaaaaattt tcatgaaaac agagataaaa cggttgcaat tcttgagatt
    16321 atttgatatt ctattttaga aatgtaagac gtattttcag aaaacatata aaatatgaat
    16381 aggagaacac aaatggaaaa gcaaacaatc actatctatg atgtagcgag agaggcaaat
    16441 gtttcgatgg ctactgtttc acgtgtcgta aatggcaatc caaacgtcaa accagcaaca
    16501 agaaaaaaag tcttggaagt tatcgatcgc ttggattatc gtccaaacgc agttgcgcgt
    16561 ggcttggcaa gtaagaaaac aacaacagtt ggggtaatca tccctgatgt cagcaatatg
    16621 ttctttgctt ctttagcacg tggtatcgat gatgtggcaa caatgtacaa atacaatatt
    16681 atcttagcaa attcagatgg taacgaccaa aaagaagtca atgtattgaa taacttactg
    16741 gctaagcaag tggacggcgt gatcttcatg ggtcaccata tcacagacga aatccgtgga
    16801 gaattttcac gttcaaaaac tcctgttgta ttagctggct ctattgatcc agatgaacaa
    16861 gtaggtagcg taaacattga ttatgtatca gcaacaaaag atgcagtaaa caaattggca
    16921 aaaagcggca ataaaaaaat cgcttttgtc agtggtgcgt tgatcgatcc tatcaatgga
    16981 caaaatcgtc tgaaaggcta taaagaagca ttaagcgaaa ataacctacc atatagcgaa
    17041 ggattgatct ttgaagcaca atacaacttc aaagatggtc tatctctagt cgatcggatc
    17101 cataatagcg gtgcaacagc tgtctatgtt tcagatgatg aattagccat cggtattttg
    17161 gatggtttat tagaccgtgg cgtgaaagta ccggaagaat tcgaaatcat cacaagtaac
    17221 aattcactac tgacagaagt agctcgtcct cgtttaacaa gtatcacaca accattatac
    17281 gatttagggg cggtatctat gcgcctattg acgaaaatga tgaataaaga agaagtcgaa
    17341 gaaaaaacga ttatcttgcc ttatggaatc gaagaaaaag gatctacaaa ataataaaag
    17401 gacaaccatt cagaggttgt gagcctgccg tttaactctg cgttacaagg agcaatttca
    17461 aaaaacagca tttcatgttt gatgaatatt gtgactcgtg attcggagtt ggcaggagaa
    17521 caccgtttat tcgggaaaag gggttatgac aaaattttgt ttaatccttt ttttttgtct
    17581 taaaaaagag agaaagtggt tgaaattaca tttatcgtat ataaaacaat ccgtgtatag
    17641 atgctgcatt atgttcacca ccatcaaaaa aataagggac tgtgtattct attaaatcaa
    17701 tcatctttct catctgattc tttggttgct tgattcgctc ttgcataagc tgaagcggtg
    17761 ttccagtaat ctgtatagtt ttcatcggta ccgccaacgc caaatttaaa ggcgcttttc
    17821 ttcggtccat ttttcgccca tagcgattca actgtttttc ctggtgtttg gatggatttt
    17881 ttattgacag taacttttcc aggtgtttga ccagtaaatc cagatacttt tttcttcatc
    17941 acatcagatg ataattcgaa tttctcatca gtgccaaaaa tgtcaggttt tgcttggtaa
    18001 gcttgattga tcagattggc aagataatta gccgaacgta tccttgcttt gctgtccatt
    18061 ccagtattgt catcgtgccc tgcccagcta ctgatggtaa tagacggagt agagacaatt
    18121 agccatgaat ctcggtattc attggtagaa ccagtttttc cgacccaatc tgcttttcct
    18181 agatttccgt ttaagcttga gatggcatct ttgaatggtg tagtgatttt tgcattgatc
    18241 acactgcgca tcatgtcatt catgatcgat gccgttgctt ccgaatagat ccggacagag
    18301 ttgctttcgt gtttataaat tacatttcct gcgttatctg tgatggaatc gatgatatag
    18361 ccttcttcat agacgccgcc gtttgctaaa gcctgaaatc cattggtctg ttgaagcgtc
    18421 gtgacatcta ctgtacctaa aggagcagat tcaacgcccc aattgtcatt tgccgggtag
    18481 ttcatctttg ccaagtagtg ctcgtaagca tattgtttcg atccaccgga attcaacaca
    18541 tcttgatata agtgataagc cgggatattg ttggaccatt ctagtgactc acggacggtt
    18601 tggaaggtgt tcgatccttc gttagtagca ttgacgattt tctcgccagc attttctcct
    18661 tcttgccaag ttgttgcata atctgataca cgggattctg atccgataag ccccatgtcg
    18721 attgcaggtc cataaacaag aactggtttg attgatgagc cagcttgacg ttctgtatcg
    18781 aaggcatggt tattttgatt ctgactgtaa ttccgtccgc caacgaatcc gtagatgcgg
    18841 ccagttctgt tatccatcaa tacatttccg gtttctactt gactgccagc accatcatct
    18901 aacatgtatc cataattttc tacgccattt tgcaatgcag catagacatc tttatcgatt
    18961 gtcgaatgga ttgtatatcc tttattttgg atcgtttgct gtgccttttg ataataagcg
    19021 tcactgaccg atgaatcaga catatcagcg ttgtcttttt cagccaattg ttgtgcaatg
    19081 attcttgttg cttcattcat cacagtataa tacaagaatt ctctgtcagt ctgttctgcg
    19141 atttgttgtg gtagaaagtc ttttgtaagg tcataggctt ttgcttcttc gtattgttct
    19201 ttcgtaattt ggccttcacg atacatactg aataaaacaa aatcttttct ggcaaggccg
    19261 gcagaaagat cttcttttag cgcacctgtg ttcgtgtatg gactatacgt gatcgggctt
    19321 tggggtaatc cagcgatata agcagcttgc ggcagcgtca catcttttgc atctacacca
    19381 aagattcctc ttgcagcttc ctggactcca gcaatgtttt gtcccttatt attacgacca
    19441 aatggtgaga cattcaaata cgtagcaatg atctcatctt ttgaaaagta tttttctact
    19501 tgtgcagaaa gaatgatctc gtttgcttta cgtttgaatg ttgtttcatc tgtaaggatc
    19561 tgctgtttga ctaattgctg tgtcaaagtt gatccaccag aagagccaat accagtagct
    19621 tcagatacta atgctcgtaa aacagcttta ggaacgtaac cttggtgttt atcgaagtat
    19681 tcatcctctg tgctgataat tgcagttttc aataaaggtg aaattttatc agatgaaata
    19741 gtcgtgcgca tcagatctgt ctggattttt gatatctctg tattatctgc ataaacaatc
    19801 tttgacgttt ctgtaatgtt tcctagttct gtctgcagtg cttttttagt cggcaattgt
    19861 gtgtcttcga cgagataggc aaaatagcca gcgcctattc caatacctag agctgcgaac
    19921 atcaaaagaa gaacagtaat aaaaacagtc aatgattgaa aaactctaaa aataatctta
    19981 ggaacaaacc atttttcttt ttttcttcta ttctgttttt ttcgagtatt tttgcgtggc
    20041 aaaagggtca cctcaactaa tggttttatt tcgctaatta tagcaaataa tagaacaaaa
    20101 aaacagacaa ggctgttttt ggcaggaatt tcttttttaa aagagttaaa acgtgagaaa
    20161 atgatctttt ttataaaaga gttcttaagc ttttctttag agaaaatttc agttactatg
    20221 gagaacaggg caaagaaaaa tcaatcattt tctttgtata tcatcttacc aatatatagg
    20281 aattgttagt aacaattgcc tttcaaggag gaatccatcc atgttattag gctcacacgt
    20341 cagcatgagc ggaaagaaaa tgctgttagg agcagcagaa gaagcagcca gttatggatc
    20401 ttcgactttt atgatctata caggcgcccc tcaaaacact agaagaaaag ccatcgaaga
    20461 gatgaatatt gatgccggaa aagcgtacat ggcagaaaac ggtctaacaa atatcgtcgt
    20521 tcatgcccct tatatcatta atttggggaa tacgatcaaa ccagaaatgt ttccttttgc
    20581 cgtccaattt ctgagagaag agattgttcg tgcggaagct ttaggcgcta ctcaaattac
    20641 acttcaccca ggtgctcatg taggggcagg aacagaagcc ggaattgcta gaattattga
    20701 aggcttgaat gaagttttga caaaagaaca gacggcacaa atcgctttgg agacaatggc
    20761 aggtaaaggt acggaaatcg gtcgaacatt tgaggaatta gcgcaaatca tcgatggagt
    20821 aaaattgaat gaaaaattat ccgttacttt tgacacctgt catacgaatg atgccggtta
    20881 taatattaaa gaagactttt caggtgtaat ggaagagttt gataagatca tcgggttaga
    20941 tcggcttaaa gtactccata tcaatgattc taaaaatccg caaggttcgc ataaagaccg
    21001 gcacgccaat attggttttg gaacaatcgg attcgacacg ctgaataaga tcgtccatga
    21061 tccaatgttt gacaatattt cgaaaatctt ggaaactccc tatgtcggca aagataaaaa
    21121 gaaagcttac gcaccatatg gaaaagaaat cgccatgttc aaagcacaaa tattcgatcc
    21181 agaagtgttt cctgagttat tagcagaaga agtgatactc taagattttc tatctgacag
    21241 cagcaaaaaa ggaccaggca cattgccttg tccttttttg tttaagaaac aaaggagtgc
    21301 tttttgcagt ctttttcatc atgcatcttc tcccccctct ttttaaattt agacaaacag
    21361 ggtatactgg tagaaaagta aaaaaacgaa aagtttcaca agcaagtggc aaaacgtgat
    21421 tggaaggacg aaaagatgct gaacacttta aaacccttga tcaaccaact aaaaaagaaa
    21481 catacatact ttattcttgg catagcccta ttatttacaa ttattcgttt gtatttatat
    21541 agtaaagcaa tctatggaac agacatgtcg gcaacctatg atgaccagct gctgattcgc
    21601 tatgctcaaa atattttgga cggtaaatgg ctaggggagt atacgactac aacactttcc
    21661 aaaggaatct cctacagctt atttttagta cttgcacata aactgcatct ttcttatgca
    21721 gttttgttcg gcatgttcag tatttttgcc agtatattgg ttgcactcgc gtttaaaccg
    21781 atcgtgaaga acaagtatct tcttttaagt ttctattttt attttttgtt ttctccgatt
    21841 agttttacac atgaatattc cactcgaacg tatcgtaatg ccctcgtgat tccggctgtt
    21901 gagatcatta tcgcttgttt actagctatt tattaccgta aatatagttc cagcaaaaaa
    21961 atgctgccgt ggtttttagg gctagctgtt tcttttcctt tcttttggtt cattcgcgaa
    22021 gattccatct ggcttcttcc ttttactgta gtcgcgttag gcatcagttt cgtccagatc
    22081 ttgctaggac aagacttttc tttcaaagaa gcaaagaagt taaaagaacg accatttctc
    22141 ctttcgaaac aagaatggct gaaactttca ttgtttttac tccctctagt cggtttctcc
    22201 atcgtctatc agtggatcga atataaaaac gagacaacat atagtattgc cgccatcaat
    22261 gaccgttcga gtggcgaatt tggacgtttg atgaaacagc tgatccgaat agatgacgaa
    22321 acgaacttaa ataaagaaaa cagtgagata tgggtctcgc atgctgcatt aaataaagca
    22381 ttagacgcat ctcctacatt tcatgctgtt tctactcgta ttgacgaatt gtatacgact
    22441 catgcgtgga cccaaggtgg aaaagtaaaa gaattaccag gagatatcat tttttgggca
    22501 ttgcgagatg tggtaagcga atctggttat taccaaaaca atgcaaaaga aaccaatgat
    22561 ttttggaaaa aagtcaatca agaattagaa gaagcctatc aaaagggaac tatcaaaaag
    22621 aaaaaagaat tctatctgat gggatcaggg gatggaaaga cgatgaatga tctgccaatc
    22681 gtatttgctt ttctgaaatc aggatatgcc tatgcatggc gatacaaaga tttccatcaa
    22741 ggggggaatt atagtttcgg tacgcaagaa caagtcgaac aggcccaaga attattgaat
    22801 cttccactaa tggataattg gatcgatagc agtgatccga gaacacctga tttccagttg
    22861 acaaaaacag caaaagtcgc gaatgtcatg ataaaaattt accaagttct ggccattccc
    22921 gtgctgattg cttcaatagc agggatatta cttatgatac taggaaccgc atttgcaaaa
    22981 gctgatcgtg cctattatag ttcctctttg attgtagtca ccggattaat actgacacaa
    23041 ttggtttttc ttttcggcgt ctcgtggttt tgttcttatg cgccagaaaa aaaggattat
    23101 tttttaagtg tctacactgg cgcaggcgtg ccattaacgc aattcatcgt agtaacaagc
    23161 atgctagttt tcagtaaatt gaatctgaaa aaagctttat cttccaaata aaaacatact
    23221 aagattagag gagaacatca ttgacgaatg atgttctcct ctattttcta tttttagatt
    23281 atagtgaaga gtgaaagaaa gttcgaacaa agccttgagg actatgagtc cctatcaaaa
    23341 accgaacttc tttactgtca ttttagaatc aggtttacgt atgttggggc catgagcccg
    23401 tgtataggaa attggaatcg aaatgaagca gtaaagttct ttcaaaactt aaaaaggagg
    23461 aaaacaaatg ccttacattc ttgcattaga tgtttcaatg ggacacagct acagtgtcct
    23521 atacaaagac gacacctgct tatttgaaga cgagatcgaa cacactcaaa gaggatttca
    23581 tgcattactc gaagagatcc agcacttgcc tgaacgtcca ttgattgttt ttgaagcaac
    23641 ggggatttat tccagaccag tcgaaaagtt ctttcaagat catcactttt cttactgttt
    23701 gttaaacccg ttagaagcga aaaaacagat ggaagaaaac accttatgca gttggaaaac
    23761 agataaatcg gatgcccatc ggctcgcaca gactcatctt aaaaatcaac gtcagccaaa
    23821 agaagtacaa agcaattttt acttagagat gcgcgattta gcccgttttt atcaagaaat
    23881 tgagaagaaa atcactcgtc tgcgcatgga tttacacaac tgccttcagt tgacttttcc
    23941 agagcttgaa cagttctttt taaacaggct gaccccttac gcattgatat tgatccgtct
    24001 ttttccccat ccagattttg tattggcatc tactcggaca aaaataaaaa ataaactgat
    24061 caacgaaaca cggaaaaaaa tctccgcgaa tcgtgccgag caaaaggcag atcaaatcat
    24121 ccactatgca cagtgtgcct atccagctgt tgaaaaagac agtatccact gtcaaaaaac
    24181 gatctattac gctgaacttc tccaagattt actcgaacaa aaagaagcac tggcgacaca
    24241 aatgatcaaa aaagccgaag gctctccttg ctttttgttg taccaaacgt tccctgggat
    24301 tggcgcactc acagccgctt tattgctcgg tgaattagga gatatcacac gatttaaaac
    24361 ccataaacaa ttgaatgcct ttgtcggaat cgacatccga cggtatcatt caggtaagta
    24421 tactggccaa gaccgcatca ataagcgtgg taatcccaaa gcacggaaaa ttattttctt
    24481 caccattcga aatatgattc gccagcaacg cgcagctcct aatcatattg tcgattatta
    24541 ctacaaatta aaaaagcaac ctatccctaa gaaagataag gttgccacag ttgcttgtat
    24601 gaacaagctt ctgaaatgta tgcacgctat ggttagggca catacagagt acgactatgc
    24661 gtacgcggtc tcagtggacc attaactaaa ccacttacag tataccactt ctttgcccag
    24721 atcgaaaatt ttttacgaac ggggctttat ttggtgtgcc ttgattttgt cgctttcgtt
    24781 tatgagctat ttttcttaca ccttttactt gactaatcgt aggaaaggga actgtgacaa
    24841 aagtcttgtc gcagttcctt tttccgaata aacggtgctc aaaagcttgc atctgcggta
    24901 ataagtccaa ccaagttaaa aacataaaaa gctgttttta cttggctgtt cttattactt
    24961 gatgcaaggc agctttttca caacctctga tacacggtgt tccagaagta acttcttcgg
    25021 aaataagccg aaatttcaca aaaatttgaa aagcaatttt cttaaattcc ttcttatttc
    25081 ttgaagctgc ccacttctga cacaacctcc tttgtgtaaa agaatcagtt tctactcgat
    25141 ttcttctatc gtttcctgca aacgctgttc atattttttg tttcctttat ataaatcacc
    25201 aatcgtccat gccaacagga gaaggacaag aacaatgatt acataagcga tttgatcagc
    25261 caatgctagt tgagctgagg tggcttgctc gccgaagaaa ctttcgattt gacctggtaa
    25321 tcctcgtaaa ttcaagtaag tcagactaat cacagagaac cagccaagta gttttacaac
    25381 aaatgaattt ttgaatcggc tccccatctc cgcttggcta ttggtcatca tcagtaaagg
    25441 aatcatcgag aatggcaatg caaaagccag aaaaacttgg gattcattca tcaagttatt
    25501 caaagcggta tgttcttcga tcgttccttt tgtacttgta aacaaaacac aaatcaatac
    25561 aggaatcaca gaaagcaatc gtgtgactag tcttcttagc caaattggga tacgcatatg
    25621 gatgaagcct tccatgatga cttgaccggt caacgtacca gtaatagtag agttctggcc
    25681 agaagcaaga agtgctacag caaataaagt agacaagata ccagattttg ctacagcaat
    25741 caagatacca ttgctcatag ctgatggatc agataaagct tcatacagac caaaaaagga
    25801 aggatcttgg acagaaccgg ttttgaatac agccacaccc atgatcaata gcagtgcatt
    25861 gactagaaaa gccattgaca actggatatt agaatcccaa gtagaaaagc gtaccgcttg
    25921 tgctacatct tcttcgtctt ggtgatcgat cttccgagtt tgagaaactg ctgaatgaag
    25981 atataagtta tgcggcatga ctgttgcacc aataatccct aaagctccag tcagcggagt
    26041 ttcgccgccg atgaccggtg agtctgagaa tgtgtgactg ttagggataa atccggcaaa
    26101 caaactgtgc caatcagggt tagacaagcc aacttgatag acgaaaacga ataaaatgac
    26161 gaaaatcaag cagacaacca aagcttcgat tttacgaaac ccgacttttg tcagcaataa
    26221 aaggacgaaa acatctaaca cagtgataaa tacggcaatt accaatggaa tatcaaaaag
    26281 caggtagagg gcgattgctg caccaatgac ttctgcgatg tctgttgcca taatggctaa
    26341 ttcagtcaag atccataaaa tgacacccaa tgtcttactt gtccgtgctc ggattgcttg
    26401 ggccaaatcc atttgggtca cgattcctaa ttttgctgcc atatattgta aaagcatagc
    26461 aatcagacta gacatcaaaa taactgacat caataaatat tggaaatttt gtccaccagt
    26521 gatcgaagtg gaccagttac ctggatccat ataaccaact gctactaatg cacctggtcc
    26581 agagtaagca agaagtgttt taaaaaaact ttttcccttg ggtacatcca ctgttccatt
    26641 tacttcagct aaagataaac catttgtatg ttcaataagt cgatgcttat gaaattgttt
    26701 gttggattga ttattcaaga aaaaaccacc tttcctattt atctacgatt acattctaca
    26761 cctcagaaag aaaaaattaa agaaaaagat ttggtatgcc taattttttt tcgtggcgtg
    26821 tcttgctggt taatgaaaga aattttgttc ttctctaaaa aaaccactat tttttgcatg
    26881 aaactaaaga atacgccttt cttttttcaa taaactttag taaaataaat cattgagagc
    26941 aattcggaaa tagaaaggag agatttatat ggtatcaaca ggtattgtcg tacttattgc
    27001 tattattgct ttgctaatcg gcgcagtagg tggctttttc ctagcgcgta aatatatgaa
    27061 agactattta gaaaaaaatc ctcccgttaa tgaggacatg ttgcgatcaa tgatgatgtc
    27121 aatggggcaa aaaccatctg agaagaaaat tcgccagatg atgcagcaaa tgaagaacca
    27181 agggaaaaaa taggttctga cccaaagact ttttgcgggc tgattttttc agtccgtttt
    27241 ttatttcgta atttgttaga ctattcagac tattcagcaa aaaagacaag cacagacaat
    27301 cctatgctct tgataaagac aaaggaggag taaaatgtcg atttttagaa aattaggttg
    27361 gttttttcga caggaaaaga aacattattt aattgggatt ttctccctat tcgcagtggc
    27421 cttggtacag ttagctcctc caaaagtgat tgggatcatc attgatgaga tcgccgataa
    27481 aaatttatca ataaagatca tttcctggtg gatcttatta ttgatccttg cagctctctt
    27541 acaatatctt tttcgttata tctggcggac gaatatttgg ggaagtgcag ctcggttgga
    27601 gaaagaactt cggcagcagc tattcaaaca ttttacagaa atggacaatc tcttttacca
    27661 aaaatatcgg actggagatt tgatggctca tgcaacgaat gatttgaatg caatccaaaa
    27721 tgtagcagga gctggtatct tgacctttgc agattcagtg atcacgggcg gaacaacgat
    27781 cattgcgatg attttgttta ttgattggcg cttaacactg attgcgctga ttcctctgcc
    27841 tttactagcc gttacttcac gagtgctggg gtcaaaactc cacgatgctt ttcgtgattc
    27901 gcaagaagct ttttctagta tcaatgataa gacacaagaa agtattactg ggatcaaagt
    27961 cattaaaaca tttggacaag aaaaagaaga tctcgcggat tttgaagaaa agattgaaga
    28021 tgcaattatt aaaaacaaac gagtcaattt tttagactcc ttatttgatc cattcattac
    28081 cttgattatc ggtctgtctt atgttgcaac aattatttta ggtggaaagt atgtcttgga
    28141 aggcacgatc tcaatcgggc agatggtctc atttattagc tatatcggta tgcttgtttg
    28201 gccgatgttt gcgattggtc gattgttcaa cgtattggaa agaggaaatg cttcttatga
    28261 tcgcgtcaat gaacttttgc atgaaaagac gcatatcgtg gaacaactgg gtgcagtgca
    28321 gactccggca aaaggcgagc tgaatgtagc tatttcctct tttaactatc cgaaagaaga
    28381 atcaccagca ttagaacaaa tcaaatttgc gatccaagaa ggagaaacat taggtattgt
    28441 tgggaaaact ggtgcgggaa aaacgacaat catcaaatta ctgatgcgtg aatacgatga
    28501 ttatcaagga aaaattcaat ttggcggatg ttcgatcaaa gaatattcat tgaatgcttt
    28561 attaggatca atcggctatg tgcctcaaga tcacttcttg ttttcgatga ccattcgaga
    28621 taatatccgt ttttctaatc caaaactttc agaagaagaa gtagagcatg cggcttcttt
    28681 agcatttatc aacaatgaaa tcaaggaatt accaaaaggt tatgatacct tagttggaga
    28741 acgtggagtc tctttatctg gcggacagaa acaaaggatt tcgattgctc gagcattgat
    28801 caaaaatcct gaattgctga tcttagatga tgcactttct gcagtagatg ccaaaacaga
    28861 agaagctatc ttgcataatt taaaagaaat aagaaaagag aaaacaacca tcattgcagc
    28921 tcaccgttta agcagcgtga tgcatgcaaa agaaatcatt gttgtcgatc aagggaaaat
    28981 cattgaacga ggaacccatc atgagctgct tgcattaggc ggctggtatg aacgaatgtg
    29041 ggagaaacag aaattagaag cgaagataga aggaggcgag gcctgatgga tgaaaattat
    29101 caatcggaat ggacaaaatc gattccactt aaagaacaga agaagatcat caaacgactg
    29161 atgaagttcg ccaaaccttt tagaagaacg ttcatcgttg ctatcttatt tgcgtttgcc
    29221 ctgtctgtga tcaatgtcct attgccaagg atcatccaaa cttttatgga tgatcatctg
    29281 gctaaacagt cggctacgac acaagttatt ttgttttttg ctggtatgta cttgtttgga
    29341 gtcatagtca aaagtatcat ttggtttttc caatggtatt tgtattccat ggcttcattg
    29401 aagacctatc agtatgttcg ggtaagatta tttgaaaagc tgcatacact aggtatgcgt
    29461 tattttgatc agacaccggc aggatcgact gtttctcgag tgacaaatga cacagaaacg
    29521 ctatttgaat tttggtatgt ctttttgatg gtattgactg ggatctttgc agtcgtttct
    29581 tccttcattg ccatgtttca aatcaatgga gaaattgcct tgtggacttt ggtgttcttg
    29641 ccgattttag gaatcgtcat ctggtattac cagaaattca gttctcgtat ttaccggaat
    29701 atgcgggaaa aattaagtca gctgaacacg aaattgaatg aatcgatttc cggcatgcgt
    29761 attatccagc agtttcgcca agaagctcgt ttagctaaag aatttgaaca agtgaacaac
    29821 gagtatttag acacgcgcta tgcgatgatc aaaacaaatt cgattctgtt aagtccgatc
    29881 atcaattttc tatatgcatt ggcgattgcg ttggcgttga ctttgtttgg gatcgatgcg
    29941 ctgcattctc ccgtagaagt tggactgatc tatgcattta cgacctatgt ccagggattt
    30001 tttaatccaa tgtctcaaat gatggacttt ttgagcacct ttacagatgg aatggttgcc
    30061 ggtagtcgta ttttgaaaat catggataca gaagaatatg caccgcaaca aaatcctgga
    30121 gcagatcaag cgattacttc aggtaagatc gagtttcgca atgtaagctt ttcttatgat
    30181 ggagagcaca atgtattgaa caatatctct tttgtcgcta atccgggaga gaccgttgca
    30241 ttagtggggc acaccggaag cggaaaaagc tcgatcatca acgtattgat gcggttttac
    30301 gaattttatg aaggccagat cttgattgat gatcatgaca ttcgagaata tccaatggaa
    30361 gagttacgta agaaaatggg attggtcttg caagatgcct tcttgtttta tggagatatc
    30421 gcaggaaata tccggatgat gaatccaact atcacagacg aacagattcg ccatgcagct
    30481 gagtttgttc aagcaaacaa gttcatcgat gaattaccaa aaggatatca ctcaaaagtg
    30541 atcgaacacg gtgccagcta ttctagcgga caacgacagc tgatcacttt tgcgcgaaca
    30601 atcgtgacag atcctaaaat actagtattg gatgaagcga cagcaaatat cgatactgaa
    30661 acagaaggat tgatccaaga aggattgaca aaaatgcgac aaggacggac aacgattgcg
    30721 attgcccatc ggctgtccac gattcgggat gcagaattga ttttagtttt agacaaaggt
    30781 catatagtag aacgtgggaa tcatgaaaca cttctagcgc aaaatggttt gtatgcagat
    30841 atgtacaaac tgcaaagcag tggtgtgtaa aaagtggttg tgacagggct ccgttcagct
    30901 ttaggtgata agaaaaaaat tgtaaaaaag gctttccaga tttttgcata aatttggctt
    30961 atcaccgata agctggtact ggaacaccgt atattagaag ttgggacagt agcatagtag
    31021 cattttgacc taagcgctag agtgaaaata aaacagagct tcccagattc ttcatctgtg
    31081 agcgttagtg tcgtaattac cagatttaaa aaaaatcacg acagctagtc agaagtgccc
    31141 aatagccgct aagaaagcgt tgacaaaagt gcttgctttc gataatataa agaaaacgat
    31201 acaacttgga tagtgattgc ctgatgcaag ctaaacctga tgagtctccc atggttccat
    31261 ggacggcttt ttgggttttt ctttttgttt tggatacagc cctatatatc atggaaagga
    31321 gtaaaacatg ctgattgaga aagtactgaa taacaacgtc gtaataacca gggatgaaag
    31381 aaatcaggaa atgatcgtga tgggaaaagg tttggcattc aaaaagaaag tgggtgaccc
    31441 gatttttgac tcatgcatcg acaaaaaatt tcagttgaca aatgacggac tttcacaaca
    31501 gttccaagaa ttggcacaag cgattcctct tgagtactta gaaatttctt gtgaaatcat
    31561 tgaatataca aaagaggctc tacaagtcca gttgaatgat tcggtgtata ttgcattgac
    31621 ggatcatttg tatacggcta tcgaacgtca caaaatggga atatttgtac caaatgtatt
    31681 gctgtatgat atcaaacaac tatttcctaa agagtatgcc atcgggaaaa aaacagtgaa
    31741 gaaaatctcg gataaatacc acatcaagtt atcagaagat gaagccggat ttatcgcatt
    31801 gcatttagtc aatgcacaag gcattcaaag ccaacaagac aatacctacc tgtttactac
    31861 aacaatacag gatattctaa atatcgtccg ctattactat aagattacat ttgatgaaga
    31921 ttcagtccat ttttttcgat tcgtcacaca cctacgtttt tttctgacac gcgtcctaga
    31981 tggagaaaaa tcagaagtgg gagaagtttc tgaggaattg taccaggtta ttcaaaaaaa
    32041 atataaggat acgtttggtt gcgttgagaa aatagcagac tttttagccg agatattcaa
    32101 ctaccagatg tccacggacg aaaaaatgta tttaacgatc catattgcgc gtttagtgca
    32161 tgagaatcgt tgtaaataaa taaaaaaagg aggataaatt aacaagaacg catgaaataa
    32221 gggtagtgac attcagttgg ctaaaccttc cactaataaa ttggagggaa tagaaatggg
    32281 aaaatatcaa gaattagcga gcaaaattgt agaaaatgtc ggcgggaagg aaaatatcaa
    32341 tggtttgaca cattgtatca caaggcttcg tttcaaatta aaaaacgaag aaaaagcaaa
    32401 tgatgagatc ttgaaaaata tggacggtgt tgtgacggta atgcgagcgg gaggacagta
    32461 ccaagttgtc atcgggaatc atgtgccagt cgtgtttgaa gaggttataa aagcaggaaa
    32521 ccttactttt gatgaggctg tttcaacaga aaaaatgaga ccgtttgata tgcttattga
    32581 tggaatatcg ggctgtttcc agccattcct tgctattcta gctgctggtg ggatgattcg
    32641 tggactgaca gcattacttg tcttcttagg cgcatttgac cgcggttctg gcacatttgt
    32701 tatgtttgat aatatcggtg attctgtatt ccaatttatg cctgttatta tcggtttaac
    32761 agctgcccgt aaatttaaag taaatgaatt cgtagggatg ttgcttgggg cagcattaat
    32821 gaatcctagc ttgtcgctgg aagctttgag tggtgcagca gaagcaccac tgactaccat
    32881 attttctggc actatttttg aagcacctat ttatcaaaca gtattcggca ttccctggat
    32941 tgcgcgtaac tacgcttctt ctgtcattcc cattatcttt attgtgttgt tagctagcca
    33001 aattcagaaa ccaattaaaa agttagtacc tgagatgatc gcgaatttct tcgttccatt
    33061 cttcaccgtt cttattacaa tgcccttagg ttttttactc gttggaccag cattcacatt
    33121 cgcaactgat attttaatgg ctggatttga aacactttta gcactttcgc cagttattta
    33181 tggagcaatc gtaggcttct tctggcaaat tctagtgatg tttggtctcc attgggcaat
    33241 cgtaccaatg ggattgatgc aattttctgt gaatggttgg caaaatatca tgacacctgt
    33301 tgcagtagtg tcttttggac aaactgcagc acttactgca ctctacttta agcttagaaa
    33361 cccaaaagac aaagcaatcg caataccagc cattgtttct ggtattgtgg ggattacaga
    33421 gccagctatt tatgggttta cattgccacg taaaaaaata tttattttta cctgtgtcgg
    33481 tggtgcgtta gggggcgcgt atagtggatt aatgaattta acttcttgga atccaggtgg
    33541 attaggcatc tttacaattc ccaactatat tagaccagat ggtgatttaa cggatgtgat
    33601 taatgtattg attggaatcg ccattgcgat ggtggtatcc tttgcgctga cttttttctt
    33661 ttggaaggag gaagcaggtg aaacagatga tagacagaaa agatcaggta aagaaattgt
    33721 aaaaacaccg atacaaggac aaatcgctcc actgaatgca gcaaaggatg cagcttttgc
    33781 acaaggaaca ctaggtcgag gaatcttgat ctaccctgaa aaaggagaag tacgtgcccc
    33841 ttttgacgga acagtcatga ccctgttccc gacgaaacat gcaatcggaa tggtttctga
    33901 agcaggtctg gaattgctga ttcatgtcgg attggatact gttcagttgg aagggaaata
    33961 ttttgaaagc ttggtgcagc aaggagaaag agtgaaacaa ggcgatctgt tgctccgctt
    34021 cgacaaaaag aaaatcgaag aggaaggata cagtttagaa acacctgtga tcgtcaccaa
    34081 ttacacggat tatttggata ttttggaaaa tcaaggggag acggtcgggc cagacgatgc
    34141 acttatcacc gcactgacct gaacggttag gtgaaagaat ggactaggct taattattct
    34201 ttttagtcca cttctttatt ttcaaaattg aaaggctctt tcatgatggc tgagctgata
    34261 gggcgtttat caaatttttg tcctacagaa attagatgga ctaaattctg ttgataattt
    34321 tctgcaaaaa cacaactata taacacgtct agaagataac aaatcgatgt attgatcgta
    34381 aaattaccaa ttttcgaata cagtcgttcg cgtgtcgtaa gtcgcaaagc ggctgtactc
    34441 attgaagata gcgttgaatc accgatactg gtcaaagcta aaattggaac atgattttgt
    34501 ttcaatattt ctgcggtacg aaggatcaca ttgttttcac ccgtataaga aatcagaatc
    34561 ccgcacatat cactcgtgca attgtacgct tcatagaacg attcaccaaa agtggtgaca
    34621 atcgtgacat ccattttgat gcgcttcatt ttcagcatga aatcttgaga aatcaaagta
    34681 ttcgagttac tggcgaaaat cacgattttt tttgcttgaa gcattagttg tttggctttt
    34741 tgcagttggt catgatgaat gagagaaagt gtatcttgaa tcgtcatctg ttctaaagaa
    34801 gccattttat ttgcgatcgt cataataccg tctgtggtgg aaaaaggaag attcgcatct
    34861 acgtcttgaa aattcccttc aagataggct gtttcagcta aaaaagcatt acgaaaactg
    34921 acccagccat caaaacccat tttttttgct acacggatga gtgtggacgg gtggacataa
    34981 catcgctcag caatctcttg gatggtcatt tcgccaagtg ctggagaatc gcttaagaga
    35041 aactgaatca cttcattttc tgaaggagaa aaggagattt ctttgatttt ttcacgtaat
    35101 aacatgtaga taccttcttc ttgttttttt acgtaaatta taactttttt gaaaatgatt
    35161 tgtaaacgga tttatgttat atagcttaat aaagacattt tttgacaaga tatttacaaa
    35221 aatccagtag aaaacactaa cttttgtaaa tgttactgga aagaaacgaa tttctattgt
    35281 ttgttttgtt tacaaaaaag ataataaaag tgtaaaaagt aaaggagtga gaacatggca
    35341 aaaggaatca aaatcgctac gattggtgga ggcagcagtt acacccccga gttgatggaa
    35401 ggatttatca aaagatatga ggaattaccg atacgagaaa tctggctcgt agatgtagaa
    35461 gaaggaaaag aaaagcttga gatcgtcagt cagatgtctc agcgtatgtg ggatgcttct
    35521 ccgtatgaag tcaaaatcta tgcaactctg gatcgggaag aagcattgaa agatgcggat
    35581 tttgttacga ctcagtttcg tgtcggtcaa ttagatgcac gaatcaaaga cgagcggatc
    35641 cctagttatt atgggatgat tgggcaagaa acaaatggtg ctggcgggat attcaaagct
    35701 tttcgtaccg ttccagtggt tttggcaatc gttgaagaca tgaagcgttt atgtccaaat
    35761 gcttggctga tcaatttcgc gaacccaagc gggatggtga cagaagcagt tatcagatat
    35821 ggcaaatggg ataaagtgat aggattatgc aatgtgccag taatggcgat gatgacagaa
    35881 ccaacaatgc ttggcaagaa aaaagaagag ctgatctaca agtttgccgg tctaaatcac
    35941 ttccattggc acaaagtagc agataataaa ggaaatgacc gcacggcaga attgattgat
    36001 cgtttatacg atgaagacaa tggattgccg aaaaatatct ttgatatccc gtttttcaaa
    36061 gaacaattaa aacaaatgaa catgatccct tgtggctacc accgctatta ctaccgtgaa
    36121 gaagaaatgc tggaacatgc tttagaagaa tatcaaacga ttggtacaag agcgcagcaa
    36181 gtgaaagaaa cagaagcaga gctgtttgaa ttatacaaag atccagaatt ggatcataaa
    36241 cctgaacaat tgcaaaaacg aggtggtgct tattattcag atgctgcctg tgaaacgatt
    36301 gcttcgatct atggaaataa agaaacacag atcgtggtat ctacaaagaa tgatggagct
    36361 gttcctgatc tgccggcaga ttgtgtagta gaagtcactg cctatgttgg cgcacaaggc
    36421 gcacgaaatg tagcgtttgg ttcccttcct gctgctgaaa gaggctggtt gcaagtaatg
    36481 aagaatatgg aattgctgac gatcgaagca gctgtgactg gtgattatgg aacagcttta
    36541 caagcgttta cgatcaatcc gcttatacga tcaggaaaga cagcaaaacg gatcatgaat
    36601 gagttgttta ttgcacatca gcagtattta ccgcaattca aggaaacaat cagccggtta
    36661 aaagcagaag gaatcgaagt ccaagatgaa ctggcaagag aattatcaag caatacacat
    36721 gtaatggagg aagtatgatg ggattcagaa aagatttttt atggggcgga gctacagcag
    36781 ccaatcaatg cgagggcggt tatgatgaag gcggacgtgg gttagcgaac gtagatgttg
    36841 tgccaatcgg agaagaccgt tttcctgtca ttactggaaa aaagaaaatg tttgaatttg
    36901 atgaaaatca tttttatcca gcaaaaattg cgatcgatat gtatcatcat tataaggaag
    36961 atattgcttt atttgcagaa atggggttca agacttatcg gatgtccatt gcttggagtc
    37021 gtatttttcc aatgggcgat gaaaaagagc caaatgaatc tggtttgaaa ttttatgagg
    37081 atgtctttaa agaatgtcaa aagtacggga tcgagccgct tgtgacgatt acacattttg
    37141 attgtccgat gcatttgatc aaagaatatg gtgcgtggcg ttccagagaa ctcgttggtt
    37201 tttatgaaaa tctgtgccga gtcatcttca atcgctataa aggacttgtc aaatattggt
    37261 tgacattcaa tgagatcaat atgatccttc atgcaccatt catgggcgca gggctgtatt
    37321 ttgaagaagg agaaaatgaa gaacaaatca aatatcaagc ggcacatcat gagttggttg
    37381 caagtgccat cgcaacgaag attgctcatg aagtagatcc ggagaacaaa gtaggctgta
    37441 tgctggcagc aggagcatat tatccataca cttgcaatcc tgaagatgtt tgggcttcta
    37501 gaaaatcaga tcgagaaaat tatttcttca ttgatgtcca gtcacgagga gaatatcctg
    37561 cttatgcatt gaaagaaatg gaacgaaatg gcattcagat caaaatggaa cctggggatg
    37621 ccgcattgct gaaagaacat actgttgatt ttatctcctt ttcttattat tcttctcgag
    37681 tttcgactac tgacaacgaa ctcttggaac agactgcagg aaatatcttt gcttctgtca
    37741 aaaatccata tctggaagca agtgaatggg gttggcaaat tgatccatta ggcttgagaa
    37801 taacgatgaa tgatatttat gatcgttatc aaaaaccact atttattgta gaaaacggct
    37861 taggtgcagt cgatacgccc gatgagaatg gttatgtgga agatgactat cgaatcgact
    37921 atctggcagc acatatccag gcaatgaaag atgcagtaga attagatgga gtcgatctat
    37981 taggctatac gacttgggga tgtattgatt tagtatcagc tggtacaggt gagatgaaga
    38041 aaaggtacgg attcatttat gtcgatcgtg acaacgaagg aaatggcaca ttagcccgtt
    38101 cgaagaagaa atcattcaac tggtataaaa aagtaattga ttcaaatgga gaaaatcttt
    38161 cgaatgattg atcaatgatt tataaaagtc tattgttttt cagcggattt ttcgagtata
    38221 ataaagctat tcgagaaacg caagcagaac aatagacttt ttttcgcatt ggctgtaaag
    38281 tatgcttact tgattaagta aaggagaatc tacatatgta tgatgtaatc gttattggcg
    38341 caggtcctgc tgggatgact gctgctttat atgcttcacg ttcaaactta tccgtattga
    38401 tgatcgaaca aggcgcccct ggcggccaaa tgaacaatac ggcagaaatc gaaaactatc
    38461 ctggtttcga ttcaataatg ggtcctgatc tagcttataa gatgtatgaa ggtgtttcaa
    38521 gatttgggac agaaaatgct tatggaatcg tgcaagatat caaggatcac ggcagccaca
    38581 aagaagttat ttgtgaagat aaaacttacg aaggaaaaac agtcattatc gcaacaggct
    38641 gtatccaccg taaattaggc gtacctggcg aggaagaatt tgctggacgt ggcgtttctt
    38701 actgtgcagt ttgtgatggt gcgtttttcc gtaacaaacg tctagtagtg atcggaggag
    38761 gagactcagc agtagaagaa gccatctatt tgacacaatt tgcttctgaa gtagtcatcg
    38821 tccaccgtag agatgaatta cgtgcacaaa agatcatcca agaccgtgca tttgcgaatg
    38881 aaaaaatttc ctttatgtgg gatacagtcg ttgacgaaat cgttgggaat gaaatggtag
    38941 tgacaggtgt gaaagcacgt aatgtcaaaa ccggcaatga gtttgatttg gcagcagacg
    39001 gagtattcat ctatgttgga ctggatccat taactgcacc atttagagaa gcagggttga
    39061 cgaacgaagc tggctggatt ccaacagaca acgaaatgaa gacgaatata ccaggcgttt
    39121 ttgccatcgg agatgttcgt gaaaaagatt tgcgacaaat cactactgct gttggtgatg
    39181 gtgggatcgc tggacaacaa gtgtataaat acttggaatc tttagaagaa acaactgcat
    39241 aagtttaaaa agagtggaag aacggtttaa ttgttctttt actctttttt ttcgcgtgaa
    39301 atctactgaa tccgatttat gcgaatactt gcaaccgtgc ttgataaaag aatcctttct
    39361 tgatttaagc gttttttggt cctcatactt tcatatctaa taagtgaatg ctatacttat
    39421 taagaaccat atttcagaaa gaggtgttat tttcatgtct tgggaacaag tgtatgaaca
    39481 atgggtacat gaagaaaatt tagaagaaaa cttaaaaaaa caattaaatg atctgggtga
    39541 agatcctgaa aaacttgaag atgcttttta tgcaccgttg gaattcggta ctgcaggcat
    39601 gcggggaatc ttagggcctg ggatcaatcg aatgaacatc tatacggtaa gacaagcaac
    39661 agaaggactt gcacgtttca tggatacaca aggcgaagaa acaaaacgcc gaggtgtcgc
    39721 tatcgcttat gactcacgcc atcaatcacc agaatttgcc atggaagcag ccaaaacatt
    39781 agcacatcac aatatcccat cttatgtatt cgaaagtcta cgtccaacac cagagctttc
    39841 ttttgcagtc cgtcatttga agacgtttgc gggaatcatg gtaaccgcat cccacaatcc
    39901 agcagcttac aacggatata aagtctacgg agaagatggg ggacaaatgc ctcctgcaga
    39961 cgcagatgca ttgacgaaat atgtccgtga agtcagcaat ccgttaaaag ttgaagtatt
    40021 atctgacgaa gaagctgaac atagcggatt gatcacgatc atcggagaag aagtggatgc
    40081 cgcttatcta gaagaaatca aagcagtaac gattgatcat gaattggtgg aaacaatggg
    40141 gaaagatttg aaacttgtgt acacaccact tcacggaaca ggaaaaatgt tgggcgaacg
    40201 tgcgttgaaa caagctggat tcgaacaatt cgtactagtt ccagaacaag ctgtcgcaga
    40261 cccagatttc actacagtca aatcaccaaa tccagaagaa cactctgctt ttgagtatgc
    40321 gatacgactt ggcgagaaag aaggcgctga tttgctgatt gcaacagatc ctgatgcaga
    40381 ccgtttaggt gcagccgttc gtttgccaaa tggctcctat gaagtattga ccggaaacca
    40441 aatcggagca ctgtttgctc aatatatttt ggaagcacac caatcgcgag gcactttacc
    40501 tgaaaacgca gcggtattga aatcgatcgt ttctagcgaa ttacctacag caattgcgga
    40561 acactatggg gctaccatgt tcaatgtatt gacaggattc aaattcattg ctgaaaaaat
    40621 tcaacaattt gaagaagatc attcccatac ttttatgttc ggattcgaag aaagttacgg
    40681 ttatttagtt aaacctttcg ttcgcgacaa agacgcgatc caagcattgc tcttattagc
    40741 agaagtagca gcttactata aaaaacaagg caaaacgttg tatgatggct tgcaaacgat
    40801 ttttgaaacc tatggctact acgcagaaaa aacgatttct gtgacaatga gcggacaaga
    40861 aggttctgcg aaaatctctg ctttgatgga aaaattccgt gaagaagcac caacagaatt
    40921 tgccggagca aaagtcatcc aaacagaaga cttcaaagag ttgacgagaa cagaccgtga
    40981 aggaaacgta gaaaaactaa cgacaccgcc atctgacgta ttgaagtata cgctggaaga
    41041 aaatggctgg atcgctatcc gtccttcagg aactgagccg aaaatcaaat tttatatcgg
    41101 tgtaaaagga aactcttcag aagacgcagc tgaaaaagta gccgcttatg aaacgattat
    41161 ccaaaagatg acagaagaat aaaaaaactt gagactgatg gaaaaagtgg taaactttag
    41221 aagtcagtct tttttcaagt tggaggtgaa tggattgcca gacacgcaaa aaacaaaagt
    41281 agagaaagtc agccaactat tcaaaatgtt gagtgacccc actcgtctca aaattctgct
    41341 gtatctgaaa gacggggaac aaaatgtgac agcaatcatc caagcagtgg aaatggaaca
    41401 atctgctgta tcgcatcaac tgcgtttatt aagagaaaac catgtcgtca agtcccatcg
    41461 tgagggaaaa gcgattttgt atagtcttga tgattctcac gtactggata ttttgaacca
    41521 gacactcaaa catgtggaac atcaataacg ataggtgcaa atagagacaa actggactgt
    41581 gtcaacgaat cttcttcgct gacacagtcc agttttttta aagaaaaatt gttagtctgt
    41641 ttcttcggtg gtttcagttc cataataact atggtcttct aggtctaaag cattcaaaat
    41701 aagcgaagct gtttcttcaa tagataaaga agcgacattg attactacgc agcccaattt
    41761 ttcataaaga tcattcgcaa aatcgagttc agctcgtatt ttttcgatat cggaataagc
    41821 agtatcagga tttaatccgt aagagcgcat ccgttcttta cggatattgt ttaaaatatc
    41881 tgggttattc gtcagtccca cgattttttt aggatcgatc tcccaaagct gtttgggaat
    41941 atgtgcttgt gggatcaaag gtagattggc aacttttaaa tttttgttag ctaaaaacaa
    42001 gctcaaaggc gttttggaag ttcgggatac gcctagcaaa acgacatctg cttctagaaa
    42061 cccacgagga tctttcccgt catcgtattt tacagcaaat tccattgctt tgatccgttt
    42121 gaaatagttc tcattcaata aatgaagggc gccaggttgc cgaatgggct tgataccagt
    42181 taagcgctcg atttctgata tcggcggagt catcacatca aaactaaata attgatgttc
    42241 ttcacaaaaa gaacgcgtca tctcgatcaa ttcttgattg atcaatgtgt gcaggacaag
    42301 agctttttct tctagtgcat cttgcagtgc ctgcatcaat gttttctcat ctgtcacaaa
    42361 tgttctgcgg aataaattga actcaacgct aggatattgg gccatagtgg cttgcgctag
    42421 ttttgtcgca gtttctccag cagagtcgga gatgacaaaa aaagtaacga tttctgtaga
    42481 atcggaagac atggataaaa cctcacttgc atttttttta tgtttattat accatactct
    42541 agaatgtgta cttcgtaatc attttgattt ggaggaataa gtcatgaaaa aacagacgtt
    42601 gatcgaacaa tcactagaaa cattgaaaaa taacggtttt aaatatacta aaaaaagaga
    42661 agcattgtta acttatttag tgaagcgcaa tcgctacgta tccgctaaag aagtttttga
    42721 ctatatgaat caggaattca aaggagtaag ttacgatacg atttatcgaa atctccatga
    42781 ttttgcagaa atcgatttac tggaagaaac cgatttaaat ggagagatga agtttcgttt
    42841 tcattgctgt caaggggaaa tcggccatca ccatcacttt atctgtacgg tgtgcggaac
    42901 aacgaaagaa atccatatgt gtccaatgaa ttatttcgaa gaacagctcg gtggatgtac
    42961 gatcgaaggg catagattcg agattttcgg aagatgtgaa aattgtcaat aaggatttaa
    43021 ataaaataac atttgataat tttaaaaaaa agcaagattt ccttgacggt caaaacagca
    43081 ttagatataa tatttacagg acagtcttgt tttttgagat atatttcaat aacaattacg
    43141 gttacttttt aagctcggag ggagggaatt aacatgtcaa aaacagtcgt tcgcaaaaac
    43201 gaatcacttg acgatgctct tcgtcgcttc aaacgttccg tgtcaaaagc gggtacttta
    43261 caagaatctc gtaaacgtga attctacgaa aaaccaagtg taagacgcaa gaaaaaatct
    43321 gaagcagcta gaaaacgcaa aaaattctag ttctgtgatg aattggagtt ggtagtgtgt
    43381 cactactaag tagattaaac gatgacatga aaacagcgat gaaagcgaaa gataaggaat
    43441 ctttacaagt catccgaatg atcaagtcat ctatacaaaa cgagcagatt aaagaaggtc
    43501 acgacttgac agaagaagaa gaattaacgg tgttgtctcg cgaaatgaaa cagcgacgtg
    43561 attctttgca tgagtttgaa gaagcaggac gtgacgattt agctgaaaaa gtaaaaagtg
    43621 aaattgtgat agtcgaaaaa tacatgccgg aacaactttc cgacgaagaa attcgacaac
    43681 ttgttcaaga agcaatcacg caaactggtg cttcatcaat gaaagaattt ggcaaagtca
    43741 tgggtgcgat catgcctaaa gtcaaaggaa aagcagatgg aaaccaagta aatgccattg
    43801 tgaaagaact attacaatct taattttatc atttaaactg cggacaatca ttgtccgcag
    43861 tttttttgtg ctcgtaaaaa agagatctaa aaaatagcta gacgaaagaa taggattctt
    43921 tcatctagct gtttttttcc tgtttaatat ttcttatgtt aaattgtgtt tgatctggtt
    43981 attcttctgg tagttcattt gcttcttgtt tataccctga taggcgatag gcgtaataga
    44041 agagtaagct gccagcatac ccaagtaacg ttgggaccat ccagccaagt cccaatgcag
    44101 caaaaggaac gtgatgatga taaaattcga gcatgcttgc tacaactctt tgttgactca
    44161 ctaaagcagg cgaatttgcc agcatatcca atacggcggg aacagcagca aacaacatcg
    44221 ttacttgata gacaaatggt gtcttttgga aaaattttgc tgttaaggaa agcaaaatca
    44281 acgcaagcga caatggatac aaaagcatca atactggtaa agaccattgg atgatattgt
    44341 ccaaaccagc atttgcaacg acaaaagaga cgaaagtcgt taaccgcagc catgtcatat
    44401 aactgacttt agggaacagt ttatggaaat cttgtgcaaa agaaacaacg agtcccatag
    44461 cggtagtgaa gacacctaat gtgaccatca ctcctaagaa gctagcgccg aagttaccta
    44521 aataaaaatt agtgatctga gaaagtgcag ttccgccatt ttctgataaa gacatcttat
    44581 tcaaactcat cgcaccgaga agaacaagac caaaatagat catgacttct agcgcaacgc
    44641 tcaggctacc agcttttgct gttaattctg tgactttttt atctttgaaa ccaaggtcac
    44701 ggactgcatg gacaaaagtg acacttaagg caagcaaggc tactgcatca accgtgttat
    44761 aaccttctag gacaccattt gttaaagcgt ttgtttggta agtatctgca gcagattgat
    44821 ttagatttcc cattgggtgg aataaagaaa cgacaaaaat gattgctaat aatgcaagaa
    44881 acaaggagtt tagatacttt ccgacgtatt tgaccaaccg tgtgggatgg acagtaagga
    44941 aataagcaag taaaaagaaa agagcagaga ataaaaacat acctaatgaa ttatattttt
    45001 caggcaaaaa tggtttagca gccatttcaa aagcagtagc agctgtccgt ggtgtaccga
    45061 aaaatggtcc gatcgtcaaa tgaacaagga ttaagaacaa ggcagcatac cattttccga
    45121 caggtttagc taagtcatac agaccatcac tttttgtcac tactacagct aagatagcta
    45181 gtaatgggaa aagagcgcct gagatggcaa atcctacgcc agcactgacc cagtttgcgc
    45241 cagccatttg acctaagtgg acaggaaaga ttagattacc tgacccgaaa aacatcccga
    45301 agataagtga actgaccatc aatagttgtt tccatgaata agtttttgtt tcttccataa
    45361 atttttcctc caataattat cattttgatt gacgatataa acgttgcagc aattagtaat
    45421 gccactaata tcagattcca tgaaaaccac caccttaaaa tataaaaaaa agcccttttc
    45481 cacttgggaa aagggctcta gattctagaa cggtaccacc ttttttcgct taaaaaagct
    45541 tcttcattca cggacgcttt ttgataaagt tatccgctag cctgataatg gaggcagcca
    45601 caatgatcta cgttttcgac attgactcgg aaatgatgtt cgtctattcg atttattgtc
    45661 atttctcact tacatgactc actgggaata aatcgttgaa tagcctactg ttttcctcga
    45721 cgctttgctg tatgtttatt tgttgacgta ataatacacc tgtttttttt gaaatgcaag
    45781 aatattttaa ctattttgtt ttcttttttt gaaacaagaa aaatacctag agaatacctc
    45841 tgaatgaaac ggaatatttt gttctccact ttcatataac ttacattctc agattctttt
    45901 tatcaaaacg agacctttag cgaatggaaa cagctatttt ttaacgtttc ttggtacgta
    45961 tggttaaacg actcttttac aaccttttct tatttgctat atagtttctt ctgagtatgg
    46021 taaaatagga aagaatgaat cgaaaaaaag gggatgtcta tttttgacgg aagagtctag
    46081 ttctttagag attagattga cagctgctga tgatgtcagc atgcttttag gtgcacacga
    46141 caagcatata aaactgatcg aggaaacaac ggaaacaacc atccatacac gtggagaaat
    46201 cattcagatc attggtgaac aatcccagat ttccttggct gcctcagtca ttcggacatt
    46261 acaggaattg atcaaacgag gaatccacgt aagtacacca gatgtcgtga cggcattgaa
    46321 aatggggcaa aaaggtacat tagattattt tgttgagatg tatgaggaag agatcgtcaa
    46381 agaccgtaat ggaaaaccta tacgggtaaa aaacagcggt caaaagaaat acgttgaatc
    46441 ggtagccaaa catgacatcg tatttggtgt agggccagcc ggaacaggga aaacgtttct
    46501 tgccgtagta ttagcaattg ctgccctaaa aaaaggcgaa gtgcaaaaaa tcattttgac
    46561 gcggcccgct gtagaggcag gggaaaacct aggctttcta cccggggatc tgaaagaaaa
    46621 agtggatcct tatctgcggc ctgtttatga tgctttatac caaatttttg gattggatca
    46681 tacgaaccga ttgatggaac gaggcgtaat cgaaatcgca ccattagctt acatgcgggg
    46741 gcggacattg gatgatgcat tcgttatctt ggacgaagca caaaacacga cagtcgctca
    46801 gatgaaaatg ttcttgaccc gtctcggtta tcaatcaaaa atgattgtca atggggatac
    46861 aagtcagata gacttgcctc gagggacgac aagtggtctt gttcatgcag aacgaacact
    46921 aaagcaaatc aaaaaaatcg attttgttaa ttttgaagca agtgacgttg ttcggcaccc
    46981 tgtagttgcc gaaatcatca aagcttatga aaaggcggat cttcatcaag aataagcttt
    47041 gcttaggagg ataagcacat gttgaataaa acactgcaga aactacaaga aaaactcgga
    47101 aaggcagcat tgcctttcct tctgttcttg ttttttatca ttgtctgcgg cgttacattt
    47161 agtagtgtca aacaaaaggc caatgatttc agagaaggcc aagtagcaga agagagtatc
    47221 cgtgcgaata aaacgatcga gaacacggaa gaaaccgaac aaagaagaaa actggcagca
    47281 gaagcagtga ctccagaata tacttatcaa aaagatctgg cagatgacca gaacaatcgg
    47341 atcaagcaat tattcgaatt gatcgataag acgaatgata ccatcaacaa atcttataat
    47401 gacaaggtag ataaggcgaa ggaagatgaa aatatcccga aacctactac agaagagcgg
    47461 attgctacac tgaagaaaaa ttttgaaaac gtgaatgcag aaaacgttgc gttttaccaa
    47521 aaactgccga acaattttta ttcgacgata tttgaaatga ctgaaacgga aattcacacg
    47581 gttagggatg aaagtttgaa gctcattgac gaacagatga gtaaacaagt tcgtgaaagc
    47641 gaattggaag cttttaaaca agaagcagaa gatcagattc agtatttgaa tgtcacaaca
    47701 gagcagcaac aaatgattcg ctacttagtg gatcaaggca ttgtagtcaa tgatgtattg
    47761 aatgagaaaa agacagaaga attaaaacaa tctgcacgag aagctgtaca accagtgatg
    47821 atcttccaag gagaaatcat tgttcgcgaa ggaaatcaaa ttgatgcttc agcgatgaaa
    47881 aaattggaat tactaggatt gacgaatcaa acgacttcga ttttcccact cattgccatg
    47941 gttttagctg ttttgcttca aatcggcgta ctgatttata attcacttca attccaaaat
    48001 gcaggagaaa gaacaaaata cgtgcttttc tatgtgacag ctatgtcagt cagcatagtg
    48061 ctgatgaaat ttttccaatt attccaaacg gaacaagcta cttatatccc gctgttttat
    48121 cccgctgctt ttgcaccact tgttttaagc tttttcttga accgaagagc agggatcatg
    48181 gctggtattt tccaagcagt atctgcactt ttcatttttt atgattcgat tggcacgaac
    48241 tttctaacga ttatcttgat gtcttatgtt ttctctgggc tcatggcaac gattgtcaga
    48301 cgcaaacgga tctcagaaca aggattatct gctgccatgt gggtcattat ttttcctgtg
    48361 atgatggatg tcattttgat cgtctatcaa ggaatgagct ttggtgatgc aacgacttgg
    48421 ttaatgcttg tctgcgggtt cactggtgca ctcttctcat tcttgctgac gatcggtcta
    48481 cacccatata ttgaattgat ggtcaatgat gacagtgtaa ttgtattaaa tgaactcagc
    48541 aatccaaatc atcctttatt gaaacagttg ctggaagaag cgccaggtac ttatcatcat
    48601 agtatgatgg tagctaatct aagtgctaac gctgtagcag aaatcggcgg acgttctttg
    48661 ctaactcgag tagcttgcta ttatcatgat atcggcaaga tcaaacatgc tagctttttc
    48721 gttgagaact tgccttcagg agcggaaaac ccgcacaatt tcttattgcc agaagacagt
    48781 aaacatatta tctttggaca tgtgacagat ggagccaaaa tattggaaga ttataatatg
    48841 ccgcaaatgg tgatcgatat ttgcaaacag catcatggaa ccacgctaat gcgttatttc
    48901 tacatcaaag cgaaagaacg caatccggaa gtaacagaag agcaattccg ttatcctgga
    48961 ccaaaaccgc aaagtcgtga agcagggatc gtcaatattg ctgacagttg tgaggctgca
    49021 gtacgggcaa tggatcatcc gacgagcgaa aaaatcgaaa gttttgtcca taatcttatc
    49081 gaagagcgta tttccgatgg tcaattagac gatagtggac tgaccttgaa agaaatccga
    49141 aaagtggaaa aatcattgat cagcggttta agtagcacct tccattctcg gatcaaatat
    49201 cctaaaatga aaacagaagt tgagaagata aaggaagaac aagaagaata gaaagaagcg
    49261 atgtataatg gatattacct ttatggatga aacaaaccaa gtctcagaag agaaaatgaa
    49321 agaaatcgat gacttgctgc aatttgcagc atcttattta aagctgccag aggaaacaga
    49381 aatgtctgtt actttcatgg acaatgcggc aatccaagta atcaatcgtg attaccgtgg
    49441 aaaagatgca ccgacagacg tcatcagttt tgctctggaa gaagaaggcg aagacgaaat
    49501 cccagtgatt tttgaagatg gagagaatcc tttgcctcgt gtactaggag acatcatgat
    49561 ttctattgaa cgtgctgctg aacaagcaga agcttacggc cattcatatg atcgggaact
    49621 tggcttttta gcggtacatg gattcttgca tatcaacggg tatgaccata tgacaccaga
    49681 agatgagaaa gaaatgtttg gtttacagaa agagatcttg gatgcctatg gactcaaaag
    49741 ataaaaacgt agagaaaaac aaacatttcc tgatgtctgt ggaatttgct gtccaaggag
    49801 tcaaaaccgt ttttgaggaa gaacgcaata tgaggaaaca tgttgcgttc ggtatccttg
    49861 ctttatttat gggcgtgatt ttccagcttg atcggataga gtggttatgg ctgcttttag
    49921 ctgtttttct cgtttggata gtagagatca tcaatactgt ttttgaaaat gtagtggaca
    49981 tgtttacgga ttttcatttt catccgattg ggaaaaaaat caaagatatg gcagctggag
    50041 cagttttagt gaccgcttgt tttgctgtca tcattgggtt gattttattt gtccctaaaa
    50101 tatatcattt gttgtttaat taaaaaggag aacgtatatg ccagaacata aatcagggtt
    50161 tgtcgcaatc gtcggccgcc cgaatgtagg aaaatccaca ttattgaacc gaatcgtggg
    50221 tcaaaaaatt gccattatga gtgacaaggc acagacaact agaaataaaa tccaaggagt
    50281 atatactaca ccagaagctc agctgatttt tatcgataca ccaggaatcc ataaaccaaa
    50341 gcatcgtcta ggagatttta tggtagaagc agcttacagt gcgttgaaag aagtggatgc
    50401 agtcttattt atgatcagtg ctgatcaaaa acgcggccgg ggagacgatt ttattattga
    50461 acgtctaaaa aacgtgcatt ctccagttta tctgattatc aataaaatcg ataagatcca
    50521 tccagacgag ttgctgggaa tcatcgaaga ttattcgacg cagatgcctt ttgcacaagt
    50581 gattccgatc tctgctacag aaggaaacaa tgtcgaacgc ttaatggatg tattagtcag
    50641 tgaaatgcca gagggcccac aatattttcc agatgatcaa gtgactgatc atcctgaata
    50701 ctttatcgtt tctgaattga tccgtgagaa agtcttgttt ttaacacgag acgaagtgcc
    50761 tcattctgtc gcagtcgttg ttgattcgat gaagcgaaac gagaatgata aaatccatat
    50821 ccaggccacg atcatcgtcg aaagagatag ccaaaaagga atcattatcg gcaaaggcgg
    50881 aaaaatgctg aagcaagtag gaacgaaagc aagaaaggat atcgaaaatc ttttaggaga
    50941 caaagtattt ctagaacttt gggtcaaagt ccaaaaagac tggcgagaca aaaaagtcta
    51001 tctgcaagac tttggctacc gaaaagacga atactgatat tctgaacttc ttataggtta
    51061 agtatagaaa taaactggat aaaaatccgc acgttgagaa aaacggcgga agatcgaaac
    51121 ataaataatc tggatcggca gaatctgctt ttccagattt attttttagg agggagaata
    51181 tgagccagct tgcagaatcg aaaggcttga ttttatctag ccgtaattac aaagaaaaag
    51241 ataaattagt caaaatcttt acggaatctt ctggcaaaat gatgttttat atcaaaggaa
    51301 tccatcggca aaatcagcca ttagctccgg ctttgctccc ctttaccgaa gcagtctata
    51361 tcggtaattt tcgaagtgaa ggtttgtcgt ttttaagcag tgtcaaagac gtccatgcgt
    51421 ttcggaacat ccaagaagat atctttttga gcggttatgg tacctatttg ctaaatctag
    51481 tagatgcagc aatcgaagat catcaatatg acccgcattt attccaattt acgcaacaag
    51541 ctctgcagcg gatggatcaa ggagatgatg cagaaatcat cacgaatatc tttgaagttc
    51601 aaatactgca acgcttcgga atcgcgccaa tttggacgca ctgtgtcgta tgcggggaaa
    51661 caaaaggaaa atttgactat tcttccaaat ctggcggtgt gatatgcgag aaacactggc
    51721 caatggacga acaccgttat catgcagatc ctcgcgctgt ttatttcgtt cgaatgtttt
    51781 cggctatttc ttatgataag atcagtggaa tccacttgaa agaagaaacg aagcaggcaa
    51841 tccgtgacct cattgaccag ttgtatgatg aatatgtcgg tattcatcta aaaagcaaaa
    51901 agttcattga tcaaatgaag tcttgggcac acgtattaaa gacgccagag aaaaatatgc
    51961 ctgaaaaaga gatacctgaa aaagaagaat aaatgaaaga tacaacaaaa aaatcaaaac
    52021 tatttgacaa atacagggac ttccgtctat tattaaccgt agattaaata gatcgttcac
    52081 tgagaggatc tattatataa acaagaaaac tgcaaaatga atacgtacat tgaccaagat
    52141 cagtaaaaaa cacgtggttt agcgagttcg ggagagtgga agccggaccc aaacgatttt
    52201 tgaagaggca cttgcgagta cgataaatga agctgccgaa tctttattcg gaagtagggt
    52261 ggaaccgcga aattattcgt ccctatgtct gtaatcagac atagggactt tttgtcgttt
    52321 tctttcctgt attcttattg acagcaacgc ttaaaaattg aaaggggcaa aacagatgag
    52381 taaaaaattg accgtccaag atatgatttt aacattacaa aaattttggt catcaaacgg
    52441 ctgcatgctg atgcaagctt atgacacaga aaaaggagca ggtacgatga gcccatatac
    52501 attcttacgg gcaatcggac cggaaccatg gaatgctgct tatgtagagc catcccgccg
    52561 accagctgac gggcgttatg gagaaaaccc aaaccgtttg tatcagcatc atcaatttca
    52621 agtcgtaatg aaaccttcac ctgaaaatat ccaagagctt tatttagaaa gcttgcgtct
    52681 tttaggaatt gatccattag aacacgatat tcgttttgtt gaagacaact gggagaaccc
    52741 atcgatgggg tgtgccggtg tgggttggga agtatggctt gatgggatgg agatcacaca
    52801 attcacgtac ttccagcaag tcggaggact accttgtaaa ccagttactt ctgagatcac
    52861 ttatggacta gaacgtcttg cttcatatat tcaagaagtt gaaagtgtct atgatctgga
    52921 atgggctgat ggtgtgaaat atggcgagat cttcaaacaa ccagaatatg aacattccaa
    52981 atattctttt gaagtaagtg accaagactt gctactaagc aactttgacc gttttgaaaa
    53041 agaagctaaa cgctgtatcg atgaaaatct tgttcatcca gcgtatgatt atattttgaa
    53101 atgcagccat acattcaatt tattagatgc tcgcggtgca gtatccgtaa cagaacgagc
    53161 aggttatctt tcccgtatcc gcaacatggc tcgtgctgta gccaaaatct ttgtggcaga
    53221 acgcgaaaaa ttaggattcc ctttattgaa taaaaacaca gcaaatccag aaaacatgaa
    53281 ggaggctgaa taagatggca aaagacttat tacttgaaat cgggctggaa gaaatgcctg
    53341 ctcatgttgt cacaccaagc atgaaacaat tagaagaaaa aacagcaaaa tttttagatg
    53401 aaaaccaatt gacttatgat acgatcgaaa cgttttctac accgcgccgc ttagcaatca
    53461 aagtaacaaa cattccagaa cgtcaagcag acagcgaaga agaagtcaaa ggaccagcca
    53521 aaaaaattgc tttggacgca gatggaaact ggacgaaagc agctgaagga tttgtccgcg
    53581 gacaaggtct gacgacagat gctatcactt ttagagaatt aaaaggcgtg gaatatgtct
    53641 atgtaacgaa atacactcac ggcaaagaag caaaagaagt attgacaggt ttagcagatg
    53701 tcattaaaag cctcactttc ccagtaacga tgcactgggc agaatacgat tttgaatata
    53761 ttcgccctat tcactggatc gtggcattgt tagatgacga aataatcccg tttgagatct
    53821 tggatgtcaa aacagacaga gcttcaagag gtcatcgttt cttaggcgaa gatgtgacat
    53881 ttacgcatgc aaaagaatac gaagaaaaat tgaatgaaca atttgttatt gcttcaccgc
    53941 aaaaaagaaa agaaatgatc atcacacaag caaacgaatt agccgaaaaa aatcactgga
    54001 tcattgatct agatgaagat ttactagaag aagtcaacaa tttagtcgaa tatccaactg
    54061 tcttttctgg cgacttcgaa gaaaaatatc tatctgttcc tgaagaagta ctagtcactt
    54121 ctatgaaaga acatcaacgt tatttcgaag tacggaacga tcaaggtatg ttgcttcctc
    54181 attttatttc tgctcgtaat ggcgatcggg taaaattgga aaatgtggta cgaggcaatc
    54241 aaaaagtatt gacggctcgt ttagaagatg cggaattctt ttataatgaa gacaagaaag
    54301 cttcaatcga ccaatacgtt gaaaaattaa aaactgttac tttccatgaa aaaatcggta
    54361 gcatctatga gaaaatgcaa cgggtacaag tcatcgctcg catcataggc gaacaagtag
    54421 gactatctga ggaagaattg atggatctgc aacgcgctgc tgaaatctat aaatttgatc
    54481 tagtaaccaa catggtagga gaattccctg aactacaagg gatcatggga gaaaaatatg
    54541 ctctgctgaa aggcgagaaa ccagccgtag caacagcgat ccgtgaacat tacatgccta
    54601 tatccagtga aggagattta cctgagacta cagtaggttc tgttttagcg attgctgata
    54661 aattagatag tatcttttct ttctttgcag ttgggatgat cccaagtggc tcaaacgatc
    54721 catatgcttt gcgccgtcaa gcatatggtg tcgttcgaat catcgaatcg aaaaaatggg
    54781 cctttccttt gtctgttctg caagaaacga ttagtgaagt tatcagtaaa gatacggatc
    54841 gttttggcat tggcttgtca gcgggacaac aacaggtgat cgactttatc aaaggccgtc
    54901 tgcgccaatt attgacaacg aagaatatcc gtcatgatgt catcgaagct gttttgaatg
    54961 cagaacaaaa agatctgaca aaagtatttg cagcagcaca attgttcaag cagcatcttg
    55021 cagatgaaga cttcaaacca tcgatggaag ctttgacacg tgtcgtgaac ttagcgaaaa
    55081 aagcggagct tgaaaaacaa tcagaagtag accctgaact gttcgaaaac gaagcggaga
    55141 aagaactgca caaagcagta gaggcaatga aaacaagctt tgctgaccaa acgatcaacg
    55201 aaaattatga tcagcttgta agccttcgcc cactgatcga aaattatttt gatcagacga
    55261 tggtcatggc agaagaacca gcagtacgta agaaccgatt aacgcaatta agtcaaattg
    55321 ctgccatggc tttgtcacta gcaagtttag atcaaatcat cacaaaataa tttctaatat
    55381 gtaaataaac cagagaacag gcacaaaata ggctatttct ctggtttatt tgttataaat
    55441 ataaataact attattaatt caatgttaat ttttttgtta ttttattttt tgtgtaactt
    55501 ttaaaaacac ctatgaaaat taaggaaata aaaatgaaat cgattaattg ttatcttatt
    55561 aatgttttat ttacttttaa atcgtaaatt gccctagtca agaaaatagt ttgtggtatg
    55621 attatatagg gaaaacttgt ttacaaatat ttctgtgaat atattaattt aattatgttt
    55681 tttaaaataa aaagctgtca tttttatgta tgtgaattat atcttaattt atctatcatc
    55741 aatacttagg agtgaatcta tggaaaagcc attcgtcaag tcattgactg ctgtggcggt
    55801 aggtgcaggt gctattgcga tctgtttgtt tggttaccat atcaataatc agcggcaaca
    55861 tcagcaacgg atcaattatg cagaatctgc catcaccaat caaaaagaca ccttgacttc
    55921 tttatcaaaa gaagtagaca agctgtatag tacaaaagaa aaaaattttc taaaccctga
    55981 aataacagaa gaaacaatca caagtttgtc aaataagcta tcctctgtca aactttcagc
    56041 agatgattac gacatcaaag aatcagaatt gcctaaagaa gctgttgcaa tccaagatga
    56101 gaagaaagca atcgtgacac agttagatag tgcagaatca aaactgaaga tccagacagc
    56161 tgtcaacgat ttatttacta aaaatgtatc aaactggcag caagctgtag acgatgtcgt
    56221 catcaaagaa aaggtgacaa gtgcagatgt cgctcgtgta cgtgaaaata tgagcttttt
    56281 taaagatagt ccttggaaaa cggttgttat gcaatatcta ggattcgctg atactcagat
    56341 cgcgcaagtc acgcaactag atcagttatt cgatacgatg ttgaaggatg gtcaagtgac
    56401 tgccaccgct acttacgatc aatatttgac ggcgctcagt caaatagagc agatccggaa
    56461 tgaaaaaata agcgcagcat acgcaacaaa agcacaaact gttgctcagc aaatgggcta
    56521 tagcaatata agttattgac agttaaaacg ttgattcaag caaggttagc aaacggagga
    56581 aactatggca agacgaagaa gaaaatcaag agggaaaaaa atatttctga ttattttagc
    56641 agttcttatc gtattagtat tagcaattgt aggagtagga gcaaaattat atctggatct
    56701 ctcacattct attgagaaaa cttacgaatc agtggaacga acccaaggag aacgaacgaa
    56761 accagttgat ctggacaaac aagaatcttt ctctgttcta ttgatgggca ttgatactgg
    56821 agatttaggt cgggtcgatc aaggaagatc agatacgatg atggttgcca cagtcagtcc
    56881 tgaagacaaa cagacaacga tcgtcagcat tcctcgagat acgtatgtcg acatcgtagg
    56941 tcgtgacaca aaagacaaga tcaaccacgc ttacgcattc ggcggagctg ccatggcgat
    57001 ggatacccta caaaaatatg tagacatccc aatcgatcac tatgtctcta tcaatatgaa
    57061 agggctaaag gaactcgttg atgcagttgg tggtatcgaa gtcaataatg acctcacttt
    57121 ctcacaagat ggctatgact ttccaatcgg taaaattaca ttgaacgggg atcaggcatt
    57181 atcttattct cgtatgcgtt atgaagatcc aaatggtgac tatggtagac aagagcgtca
    57241 aagaaagatc gtagaaggtg tagcaaaaaa agtattgagt ttaaacggtg tcagcaacta
    57301 tcaatccgtt ttgaatgctc tagagtcgaa tatgaaaaca gacatgagct ttgatgaaat
    57361 gaaaaaaatc gctttagatt atcgggaggc atttggtacg atcaagcaag atcagctgca
    57421 aggagaaggc ttcatgcaag ataatatctc ctatcaaaaa gtcagcgatc aagaacttga
    57481 tcgtgtgaaa aaagaattaa aagatcaaat gaatctagag aataaatagg aaagtggaga
    57541 aaaaatggaa gagacaatca gcttgaaaga aatttttgaa acattacgca aacacttggt
    57601 aacaatcatc atctcaatgt ttgctggctt ggccatctca ggaatcgtaa catttttcat
    57661 cttgacacca aaatacagtt cacaagcaca attgatcgtg acactgccac aatcagacac
    57721 agcaaatgtc aatgatgtca atacgaacct gcaaatgatc aatacgtata aagatatgat
    57781 cgtcagtgat ttagtactaa atgaagtcaa agatcgttta gaaacagaag acaatgtgaa
    57841 aatgactgct ggacaaatca aagatgcgat ctccgtcaat cagtcacaaa attcacaaat
    57901 gttctcgatc caggcaataa gcacgaatgc agtgactgct caacagatcg ctaacacaac
    57961 ttcacaagtt ttccaagaga acgcaaaaga cgtgatgaat gtcgataaaa tctcgattat
    58021 ttcaggtgca gttgccaata cgacacctgt ttcgccaaat aataaattga atctagtgat
    58081 tggcttagta ttaggaatga tggtaggcgt aggtctggca ttcttattcg aattacttga
    58141 tcggacagtg aaagatgaaa aatatgtgac ggatgcatta ggattcccaa tcttaggaac
    58201 agttccagaa atgtcagcga aagaattgaa cgctggtatc cgtaaaaaag gaacagctcc
    58261 tgcacgacca aaagctacaa acgataaaac agccccatca cgcagaagcc gctcaagagt
    58321 ctaggaggaa gaaaaatggc acgaacacag aaacaaaaag cagcacaaac tcatgcagtc
    58381 agtttgatca cattaacaaa cccatcttca ccaatcgccg aacaatatcg tacgatccgg
    58441 acgaatatcc agtttgcctc cgcagctggt cagcaaatca aaacgattgt cgtgacttca
    58501 tcaggtcctg gagaaggaaa atccaccact gcagcaaaca ttgcagtcgt ttttgctaaa
    58561 tccggtcaac gagttctact agtcgatgca gatttacgta aacccgtcgt ctataagaca
    58621 ttccagctga acaatgccag gggattaagt acagcactta gttcatcagg aagtgtagca
    58681 gatgtaatcc aacgaacgcc agtcgagaac ttgtcgattt tgcctagtgg acctaagcca
    58741 cccaacccat cagaattgtt aagttcgcca agaatggatc agatcctaga cgaagcaaga
    58801 cagttatttg acgtggtgat attcgatatg ccaccagtag tagccgtaac agatgcacag
    58861 atcatgtctt caaaaacgga tggcacttta ttggtcgtac gtgaaaatac atcacgtaaa
    58921 gaatcattga ataaagcaaa agaactgcta gagatggtac aagcacgagt tttaggtgtt
    58981 gtatacaacg gagcagaaca tagcaaagat gctggttatt actacggaaa ttaaggaata
    59041 agaagagagg agacaagaga aatgatcgat ctacattgcc atatcctacc aggaatcgat
    59101 gacggggcag aaaacttaga agcaagtatt gcaatggctg aaaaagcgat tcagcaaggc
    59161 atcacgcata ttttatgcac accacaccac aataatggaa aatacagcaa tgaaaaatca
    59221 caagtcattt ctctagtcgc ttcgttacaa gccgaattag agaaaagaca gttgcctttg
    59281 acgttattgg aaggacaaga agtacgtatt accggaacgc tcatcgaaga catccaccga
    59341 gatgaaattt tatttacaga tttagatgat acatatcttc tgatcgaatt tccgacactg
    59401 gaagtgccgt tatatgcaga acggcttttt tttgagttgt tagaactagg aaagacacca
    59461 gtgatcgtcc atccagaacg caacgcgcat tttcgcgaag acccgaatca tttgcttccg
    59521 ttcctagata tggggtgttt ggcccaactt actgcgccaa gttatgttgg ggtatttggc
    59581 aaagatattc agaaaacagc taaaacaatg gtcaaacata atctcgtgca gatgactgct
    59641 tctgatgcac acggagtctc taagcgcacc ttttacttaa aagagtgcta tgagcagatt
    59701 gccaaggact ttggtaagga aaaagtagta cagatgaagc aagttgcaaa ggatctgatc
    59761 aacggggatg aaatcagtta tccagactat gaagaggtaa aaaagaagaa gtttggttta
    59821 ttttaggggg aattaaaaag tgtttatatt aacaagaaga agaaaaattg ccacattggt
    59881 ttttgtggac agcttgttat taattgctgc aaatattgca gcagctaaat tcatgaagcc
    59941 gtttgtatct ataccaatgg atcttatttt aatctctatc ggtttgtcga ttggttttta
    60001 tttattttat ggtagtttat tcaaagtttt cactcggatc aatcgctata caaatttaag
    60061 agagatcatt gcaattttta gttcactatc tgcaagtgct gcctcaagta tcctcatact
    60121 gctgttcatt aatcggcgat acagtttacg gttagttatc tttgcttatc tgctttcgct
    60181 cttattgatc atcggtagcc gattgatctg gcgtatctac atcgaaacaa aaaatatgag
    60241 atacgtatca gcagattctg ctaaaaatac attgattgtt ggtgctggcg aaggcgggcg
    60301 tattttatac aacagctttc ttggatccaa aacggctcaa gatatccacg ttgtcgggtt
    60361 tgtagatgat gatccaaata aaagaaatac gtatctttca ggaaaaaaag tattaggtgc
    60421 attaaaagat attccggaat tgattgaaaa atatgacatt caaatggtaa cgatcgctat
    60481 cccttcctta tcaagaaaaa aattacgacg aatcttcgag ttagtcgaat ccgctcgtgt
    60541 gaaagtcaac acgatgcctt ctatagaaga acttgcttca gggaaaatta gcgtatcaaa
    60601 attaaaaaca attgacgtag tggatttact gggaagagat gaggtaaagc tggatattga
    60661 atccatcaaa gatcagatca cagacaaagt cattcttgtc accggcgcag gaggatcgat
    60721 cggttcagaa atctgtcggc aaatcattca attcaatcct gcaaagctat tgcttttagg
    60781 acatggggag aactcgatct acttgattga ccgtgagtta cgcacgcatc atcaaaattg
    60841 tcctacagaa atcgtaccga tcatcgcaga tatccaagat cgcgagaaaa tcaatgagat
    60901 catggaacaa tatcatccag atatcgtcta ccatgcagct gctcataaac atgtaccact
    60961 gatggaatat aatccaaaag aagcagtcaa aaacaatatt ttcggtacaa aaaatgtagc
    61021 agaagcagct aaagcagcaa aagtgaaaaa cttcgtcatg gtatcgacag ataaagctaa
    61081 caatcctcca aatgtcatgg gttcaacaaa acgaatcgct gaaatgattg tgactggatt
    61141 gaatgaagaa ggctgtacga aattctcagc tgtcagattt gggaatgtcc ttggttctcg
    61201 cggtagtgtg attccagtat tcagagaaca aattgctcaa ggtggtccaa tcactgtaac
    61261 agactttcgt atgactcgat actttatgac gattcctgaa gctagtcgtt tagttattca
    61321 atctggcgca ttagcaaaag gtggcgaaat ttttattcta gatatgagtg aaccagtgaa
    61381 gattgtagac ctagcgaaaa acatgatccg attgagcggg tatagcgaag acgaaatcga
    61441 aatcattgaa acaggtatcc gtccagggga aaaactatat gaagaactat tgttggataa
    61501 ggaaagaaat gatgaagcag tttatgagaa aatctttgta ggaaacatca aaggttactc
    61561 aatacaaaaa gtgatggatt ttgtcaagag cctgccgcaa gacgatgaac aattggctaa
    61621 agacattgtc acttttgcaa atgcttcgaa tagataggag attaaaaatt gaatatttta
    61681 atattaagtt gtggacgtcg ttgtgaacta gtgaatgcat ttaaaacagc attaaacaat
    61741 aatgaaatgg aaggaaaaat cattggagca gattgctctg aactagcacc cgcactatat
    61801 atgtgtgacg aaaaaatagt attacctaaa gtttcagaaa gtaattatat tgaggaatta
    61861 ataaaagtaa taaagttttt tgaaattaaa ttaattgttc ctactattga tactgaatta
    61921 tcaacattat caagaaataa aaaatatatt gaaaatgaaa cagactcagt tgtattagtt
    61981 tcttcagaaa aagtcatcga catttgtgag aacaaaattt taacttctgc tttttttgaa
    62041 caaa
//
LOCUS       DAFLVO010000008        61399 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.008, whole genome shotgun sequence.
ACCESSION   DAFLVO010000008 DAFLVO010000000
VERSION     DAFLVO010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61399
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.008"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..844)
                     /locus_tag="L1U99_000519"
     CDS             complement(<1..844)
                     /locus_tag="L1U99_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBN1211090.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDS"
     gene            complement(1068..3008)
                     /gene="thrS"
                     /locus_tag="L1U99_000520"
     CDS             complement(1068..3008)
                     /gene="thrS"
                     /locus_tag="L1U99_000520"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBN1211091.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3345..3524)
                     /locus_tag="L1U99_000521"
     CDS             complement(3345..3524)
                     /locus_tag="L1U99_000521"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HBN1211092.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3571..5394)
                     /gene="cadA"
                     /locus_tag="L1U99_000522"
     CDS             complement(3571..5394)
                     /gene="cadA"
                     /locus_tag="L1U99_000522"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBN1211093.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5672..7951
                     /locus_tag="L1U99_000523"
     CDS             5672..7951
                     /locus_tag="L1U99_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1211094.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8044..8691)
                     /locus_tag="L1U99_000524"
     CDS             complement(8044..8691)
                     /locus_tag="L1U99_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211095.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(8870..9589)
                     /locus_tag="L1U99_000525"
     CDS             complement(8870..9589)
                     /locus_tag="L1U99_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1211096.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9720..10871)
                     /locus_tag="L1U99_000526"
     CDS             complement(9720..10871)
                     /locus_tag="L1U99_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBN1211097.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11088..11828)
                     /locus_tag="L1U99_000527"
     CDS             complement(11088..11828)
                     /locus_tag="L1U99_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1211098.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(11832..12155)
                     /gene="rsfS"
                     /locus_tag="L1U99_000528"
     CDS             complement(11832..12155)
                     /gene="rsfS"
                     /locus_tag="L1U99_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBN1211099.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12212..12805)
                     /gene="yqeK"
                     /locus_tag="L1U99_000529"
     CDS             complement(12212..12805)
                     /gene="yqeK"
                     /locus_tag="L1U99_000529"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBN1211100.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(12789..13439)
                     /locus_tag="L1U99_000530"
     CDS             complement(12789..13439)
                     /locus_tag="L1U99_000530"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBN1211101.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13449..13760)
                     /gene="yhbY"
                     /locus_tag="L1U99_000531"
     CDS             complement(13449..13760)
                     /gene="yhbY"
                     /locus_tag="L1U99_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HBN1211102.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(13776..14885)
                     /gene="yqeH"
                     /locus_tag="L1U99_000532"
     CDS             complement(13776..14885)
                     /gene="yqeH"
                     /locus_tag="L1U99_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HBN1211103.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(14882..15409)
                     /locus_tag="L1U99_000533"
     CDS             complement(14882..15409)
                     /locus_tag="L1U99_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HBN1211104.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15589..16374)
                     /locus_tag="L1U99_000534"
     CDS             complement(15589..16374)
                     /locus_tag="L1U99_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HBN1211105.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16367..17236)
                     /locus_tag="L1U99_000535"
     CDS             complement(16367..17236)
                     /locus_tag="L1U99_000535"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBN1211106.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17237..18616)
                     /locus_tag="L1U99_000536"
     CDS             complement(17237..18616)
                     /locus_tag="L1U99_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBN1211107.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18624..19043)
                     /gene="fabZ"
                     /locus_tag="L1U99_000537"
     CDS             complement(18624..19043)
                     /gene="fabZ"
                     /locus_tag="L1U99_000537"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBN1211108.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19068..19544)
                     /gene="accB"
                     /locus_tag="L1U99_000538"
     CDS             complement(19068..19544)
                     /gene="accB"
                     /locus_tag="L1U99_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBN1211109.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19547..20782)
                     /gene="fabF"
                     /locus_tag="L1U99_000539"
     CDS             complement(19547..20782)
                     /gene="fabF"
                     /locus_tag="L1U99_000539"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBN1211110.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(20801..21538)
                     /gene="fabG"
                     /locus_tag="L1U99_000540"
     CDS             complement(20801..21538)
                     /gene="fabG"
                     /locus_tag="L1U99_000540"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBN1211111.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21550..22467)
                     /gene="fabD"
                     /locus_tag="L1U99_000541"
     CDS             complement(21550..22467)
                     /gene="fabD"
                     /locus_tag="L1U99_000541"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBN1211112.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22574..22798)
                     /locus_tag="L1U99_000542"
     CDS             complement(22574..22798)
                     /locus_tag="L1U99_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBN1211113.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(22851..23813)
                     /locus_tag="L1U99_000543"
     CDS             complement(22851..23813)
                     /locus_tag="L1U99_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBN1211114.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(23823..24263)
                     /locus_tag="L1U99_000544"
     CDS             complement(23823..24263)
                     /locus_tag="L1U99_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1211115.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            24569..25534
                     /locus_tag="L1U99_000545"
     CDS             24569..25534
                     /locus_tag="L1U99_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBN1211116.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(25591..25821)
                     /locus_tag="L1U99_000546"
     CDS             complement(25591..25821)
                     /locus_tag="L1U99_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HBN1211117.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(25907..26794)
                     /locus_tag="L1U99_000547"
     CDS             complement(25907..26794)
                     /locus_tag="L1U99_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBN1211118.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(26883..28106)
                     /locus_tag="L1U99_000548"
     CDS             complement(26883..28106)
                     /locus_tag="L1U99_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBN1211119.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(28123..29169)
                     /locus_tag="L1U99_000549"
     CDS             complement(28123..29169)
                     /locus_tag="L1U99_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBN1211120.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(29333..31060)
                     /gene="ptsP"
                     /locus_tag="L1U99_000550"
     CDS             complement(29333..31060)
                     /gene="ptsP"
                     /locus_tag="L1U99_000550"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBN1211121.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(31060..31326)
                     /locus_tag="L1U99_000551"
     CDS             complement(31060..31326)
                     /locus_tag="L1U99_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HBN1211122.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            31805..34039
                     /locus_tag="L1U99_000552"
     CDS             31805..34039
                     /locus_tag="L1U99_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1211123.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            34187..34507
                     /locus_tag="L1U99_000553"
     CDS             34187..34507
                     /locus_tag="L1U99_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBN1211124.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(34712..34936)
                     /locus_tag="L1U99_000554"
     CDS             complement(34712..34936)
                     /locus_tag="L1U99_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HBN1211125.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(35134..36714)
                     /locus_tag="L1U99_000555"
     CDS             complement(35134..36714)
                     /locus_tag="L1U99_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HBN1211126.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(37115..38491)
                     /locus_tag="L1U99_000556"
     CDS             complement(37115..38491)
                     /locus_tag="L1U99_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBN1211127.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(38619..39737)
                     /locus_tag="L1U99_000557"
     CDS             complement(38619..39737)
                     /locus_tag="L1U99_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBN1211128.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            39879..40313
                     /locus_tag="L1U99_000558"
     CDS             39879..40313
                     /locus_tag="L1U99_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1211129.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(40391..40924)
                     /locus_tag="L1U99_000559"
     CDS             complement(40391..40924)
                     /locus_tag="L1U99_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HBN1211130.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(41018..42196)
                     /gene="mutY"
                     /locus_tag="L1U99_000560"
     CDS             complement(41018..42196)
                     /gene="mutY"
                     /locus_tag="L1U99_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HBN1211131.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(42189..42986)
                     /gene="recX"
                     /locus_tag="L1U99_000561"
     CDS             complement(42189..42986)
                     /gene="recX"
                     /locus_tag="L1U99_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBN1211132.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            43093..44475
                     /gene="rlmD"
                     /locus_tag="L1U99_000562"
     CDS             43093..44475
                     /gene="rlmD"
                     /locus_tag="L1U99_000562"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBN1211133.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(44649..45227)
                     /locus_tag="L1U99_000563"
     CDS             complement(44649..45227)
                     /locus_tag="L1U99_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HBN1211134.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            45549..46019
                     /locus_tag="L1U99_000564"
     CDS             45549..46019
                     /locus_tag="L1U99_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBN1211135.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(46127..47353)
                     /locus_tag="L1U99_000565"
     CDS             complement(46127..47353)
                     /locus_tag="L1U99_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBN1211136.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(48107..48307)
                     /locus_tag="L1U99_000566"
     CDS             complement(48107..48307)
                     /locus_tag="L1U99_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBN1211137.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(48441..49049)
                     /locus_tag="L1U99_000567"
     CDS             complement(48441..49049)
                     /locus_tag="L1U99_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBN1211138.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(49134..49604)
                     /locus_tag="L1U99_000568"
     CDS             complement(49134..49604)
                     /locus_tag="L1U99_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBN1211139.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(49652..50566)
                     /locus_tag="L1U99_000569"
     CDS             complement(49652..50566)
                     /locus_tag="L1U99_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBN1211140.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            50712..51515
                     /locus_tag="L1U99_000570"
     CDS             50712..51515
                     /locus_tag="L1U99_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HBN1211141.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            51693..52640
                     /locus_tag="L1U99_000571"
     CDS             51693..52640
                     /locus_tag="L1U99_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBN1211142.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(52708..53001)
                     /locus_tag="L1U99_000572"
     CDS             complement(52708..53001)
                     /locus_tag="L1U99_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HBN1211143.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYNPNLEEPTYHFKKQ"
     gene            complement(53029..53694)
                     /locus_tag="L1U99_000573"
     CDS             complement(53029..53694)
                     /locus_tag="L1U99_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBN1211144.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(53834..54466)
                     /locus_tag="L1U99_000574"
     CDS             complement(53834..54466)
                     /locus_tag="L1U99_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1211145.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(54473..55540)
                     /locus_tag="L1U99_000575"
     CDS             complement(54473..55540)
                     /locus_tag="L1U99_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBN1211146.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(55537..56268)
                     /locus_tag="L1U99_000576"
     CDS             complement(55537..56268)
                     /locus_tag="L1U99_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HBN1211147.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(56437..56916)
                     /gene="greA"
                     /locus_tag="L1U99_000577"
     CDS             complement(56437..56916)
                     /gene="greA"
                     /locus_tag="L1U99_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBN1211148.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(57052..58227)
                     /gene="mltG"
                     /locus_tag="L1U99_000578"
     CDS             complement(57052..58227)
                     /gene="mltG"
                     /locus_tag="L1U99_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBN1211149.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            58431..59600
                     /locus_tag="L1U99_000579"
     CDS             58431..59600
                     /locus_tag="L1U99_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBN1211150.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(59867..60781)
                     /locus_tag="L1U99_000580"
     CDS             complement(59867..60781)
                     /locus_tag="L1U99_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211151.1"
                     /translation="MIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDSELLSFGIG
                     LTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLNIIQAPWRF
                     MIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNMVKEMNFQG
                     TYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPNKDEITFTF
                     KSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTIRYSYTFFS
                     KISLFISIITLIVLLFYCIKLKIRTSHE"
     gene            complement(60839..61399)
                     /locus_tag="L1U99_000581"
                     /pseudo
     CDS             complement(60839..61399)
                     /locus_tag="L1U99_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177099.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT        17953 a        12790 c        10316 g        20340 t
ORIGIN      
        1 tcgaatccat aaaatattct tggattgctt ctcgtgtttt tttcactttt tcgctaagct
       61 tttcgttttt agccatatag aaataaaaaa tgatatcgat cgtagcaaat tgggccaaaa
      121 gtgaattagt tgccgcactt cgattcgtga tttcttttgg tctagatgtt tgtacgagta
      181 catcggctat cttgctaagc gggttatttc caaattgcgt caacgcaatg atttcgatat
      241 tcatgctttt cgccagctcg gctaatgcga ctacatctgc acttctacct gagtttgaaa
      301 caagccaaag cactttcttt ttctcattgc tgacaagttg cgggagcaag acgtggatat
      361 ctttttcaaa aatgattggc ttaccgacac gagaccattt ttgcagaata tcttctacta
      421 ctaaagaaga ggcgccaacc ccatataaaa aaacagtctc tgccgattcc aaacactcta
      481 cgactttttg gatcgtttct tcttctagaa tatctactgt ttcttttatc gctacttgtg
      541 cattgttacc aagtttgttt ttgatagagt aaaaggactc atttgcttct atatcactaa
      601 aaccttcatc gattccagtc tgtagttctg ttgaaatcgt gattttgaag tccgtcagac
      661 tttgaaaacc gatttttttg gaaaaacgta caactgtcgg cgcactcaac ccggaagctt
      721 ctgctaattc attagctgtc attgtaggga ccttctcaat attaccgata atgtagttgg
      781 ccaacttttt ttctgctgaa gaataatctt ccatcatact ttcaatacga ctaattacgc
      841 tcataagttc ctccaccctt ttaatgatag tctatgtaag tataccatat cagaccctta
      901 ttcacggtcg tatactggat aaaaaacaaa aaaacaatcc gcccaacaga atatcttatc
      961 ccatcaatcc cacagattct attgagcatc tgtgtctttg aggaatacct gttatctatt
     1021 gttcggattg ctttctatct actacttttt tacaggaaat ttacctatta gttttctctg
     1081 ctgtaatttt tgacttctgc ttccatagca tcaataaaga tattcaaatc ttctacagct
     1141 gtttctttac ttccataacg acgtacgttc actgttgcat cttccaattc cttgtctcca
     1201 acaactaatt ggtaagggat cttttgtgtt tgagaggcac gtatcttata gcccattttt
     1261 tcattacgat catcaacttc tacacgcaac cccttcattt gcaaacgttc tttgatttca
     1321 taagcataat cgccatgtgc atcaacagaa acagggatga ttgttgcttg tataggtgcc
     1381 aaccatgttg gaaaagcgcc tttgtatact tctgttaaat aagcgacaaa acgttccatt
     1441 gtagaaacaa ttccgcggtg gataactact ggacgatgcg tattttcccc gtcttctcca
     1501 acatatgtca aatcaaagcg ctctggcaat aagaagtcta attgtatagt tgataatgtt
     1561 tcttctgtac caagagctgt tttgacttga acatctagtt ttggtccgta aaaggctgcc
     1621 tcgccttctg cttcaaagta atctagttct aattcatcca tagcggcttt cagcattgct
     1681 tgggcttttt cccacattgc gtcatcatca aaatatttat ctgtattgtt tggatcgcga
     1741 tagctcaagc ggaaacgata atctgtaata ttgaagtcag catatactgc caccatcaat
     1801 tcaagcgtac gtttaaattc atctttgatt tgatcaggac gaacaaatgt atgaccatca
     1861 ttcaacgtca tttctcgtac acgttgtaaa cctgacaaag cacctgattt ttcatagcga
     1921 tgcatcattc ctaattcagc gatacgaatt ggtaattcac gataagaatg gatcgtgttt
     1981 ttgtagacca tcatgtgatg agggcagttc attgggcgaa gaacaagcat ttcgccatct
     2041 cccatatcca ttggcgggaa catgtcttct tgataatgat cccagtgtcc agatgttttg
     2101 tacaactcaa catctcccat tattggtgta tatacatgtt ggtaacctag actaacttct
     2161 ttgtctacga tataacgttc gatcgtgcgt cggattgttg ccccttttgg aagccagaat
     2221 ggcaaaccag aacctacttc tggggaaacc atgaacaagt caagttcttt tcctagttta
     2281 cgatggtctc tttcttttgc ttcttcacgg agacggatat attctttcaa agctttcttg
     2341 tcaaaaaagg ctgtcccgta tacacgttgc atcatttgat tgtttgagtt tccacgccaa
     2401 taagcacctg ccactgataa taatttaaat acttgtatac ggccagtgga tggaacatgt
     2461 ggtccacgac acaaatcgat gaattcgcct tgttgataag cagtaatcac ttcttcttct
     2521 ggcaattcac taatcagttc tactttgtac ggatcacttg caaaaatttc taatgcttcc
     2581 tgttttgaaa gaacacggcg ttcgatcggc agattttctt tgacgatttt catcatttct
     2641 gcttcgattg ccggcaaatc ttctgcagtt acttggtttt gtccattatc tgtatcgtag
     2701 taaaaccctg aatcgatagc tggtccaacg ccaaagtgga tatttggata gaggcgacgc
     2761 atggcttggg ccatcaaatg agctgctgaa tgacggacta agccaagtgc atcttcatgg
     2821 tctggtgtga tgatctcaat acttgcatct tcctcgattg gacgagtcaa atcaacgagt
     2881 tttccgttca ctttaccagc taaagctttt tttgctaagc tttttgaaat gctttcagca
     2941 attgccaatg ttgttgttcc agactcaaat tctttgactg caccatctgg aaaagtaatt
     3001 tttatcataa tagtttcctc cttgaaatgt tttgattgat cagatcatca agctgaaaaa
     3061 caaaaaaatc ctagcatctc ttgaaaagag atactaggac gaaaagttcg tggttccacc
     3121 taatgttcaa acgcaaatgc gttcctcaag cgttgtaacg gtccgaccgc ccttgcttca
     3181 acaagggttt cgaaagtggt catcctttgg ttttctcctg gaaaagtttc agcctagctt
     3241 ttcctctctt atcgaagact ctcaaattca gttggctttc tcatcaatca attatgtgtt
     3301 tatttaacca ctaataaata gaaaaatcaa gtgggaaact aaacttattt tttccattcc
     3361 ccatttacac cgtatgttcc ttttttcatc tcattgatga tgacatggat gtgttctttt
     3421 ggtgcctgcg tgtttttatg aacagcttcc gtgatatctt tcatcatatt ttctaattgt
     3481 tccggactgc gaccttctac taattcgaca tgtacgaatg gcataatgct ctctcctctt
     3541 tctgatcgtt cttttttcaa ctcgattcta tcatactatg tttgtcttgg gtactgaatc
     3601 aggaaaaatg gctggatctt tttttgctct caaggcactc aaaatagaga ccgtatccac
     3661 gacttcttgc aaaacagctc cgaataatgc ggggattagt cccgtacttg caattaacat
     3721 caaaaaaata caaataaaga tgccaatcag tacagactgt ttcgctattc tcatcgtatc
     3781 tcttgaaatc actactgctt ttgctacacg caagagatca tctttcaaga tgaccgcatc
     3841 tgcactttca ctagcagctg tagaaccatg agcccccatt gcaataccga tatctgcagc
     3901 agcaagtgct ggtgcgtcat tcacgccgtc tcctaccatc gcaacaggtc tttgatcttt
     3961 agggatactt tctaaaatgg tcagtttatc ttgaggcaag ctacgggcat gtacagaatc
     4021 taattggact ttttctgcaa tcgtttgagc aatggcagat ccatccccgg tgatcatcat
     4081 caaatttttc acatcaagtt ttcttagctc cttgattgtc tttgctgctt ctgggcgaat
     4141 ctgatccgaa aataggatcg ttcctgcaaa agatcgatca attgttacat agattgctgt
     4201 attggacgtt tctatttctt cagctgaaac aaaagaggca cgtccaatct ttacttcatg
     4261 attattgact actgcttgga ttccttgacc ggtcacttct ttcagttgac taacaggata
     4321 cagttggctg tttttcacgt tgttcactaa cgaacgagct aagatatggc tagattcctg
     4381 ttctgcacta gctgcataca gaagtagctc ttcttttttt attccattga ctggctgaat
     4441 cgcctctact tccaatatcc ctttggtaag cgttcctgtt ttatcaaaag caatcgtttt
     4501 tgtacgtgcg agcttttcaa tcgttgttcc agtttttaca acgatcccgt ttttacttga
     4561 acggctcatt cctgcaacta aagcaatggg cgcagctaga atcagtggac aaggtgatgc
     4621 cactaccagt acctcagcaa atcgtaaagg gtcttttgag aaccaccaag aaataccacc
     4681 gatcaaataa gcaatcaacg tgaaagggac tgcataacga tcagctaaac ggacaaatcg
     4741 ggcaggcttt tcttttgatt cttcgactag tttaataatc atttgatact ggctgtctgc
     4801 ggcacgtttt tcagcgatca tttggatcga tccgtctcca tttaaagacc ctgacataat
     4861 ctgatctcca ggtttcttgg tttccgggcg ggactcacct gtcaaagaag attcatcgac
     4921 cgaagattct cctttggtca ctcgaccatc tgcgggtaca agttcgccag gcttgactag
     4981 taactggtca tcaatattta tttcatcgat tactatatcc tgcaattttc cttctttgaa
     5041 tcgatgggca attcttgggg tgttatctaa caaagactgc agttctttac ccgctcgttt
     5101 attcgcgtaa tcctctagac tatctccgcc cgtaagcatg atcaatatca tcaaactagc
     5161 ccagtattct ttgacggcta atgttgcaag gattgcggta atcgctaata catctacgcc
     5221 atatcttcct gaacgtaacg tcttgatcat ttccaaaaac atcaagaagg cgagaatccc
     5281 tccagtaaat gcgacaatcg caaatgcaag ggccggctgg tgaaaaacaa attcacttaa
     5341 taaagctatc ccaccaataa gcaaagtaag taaaaatttt ttgaaatgtg tcattgtttt
     5401 ttctcctctt ttatgtgact tagagaggtt agtaataaat ttccagctgc ctctttcatc
     5461 ttaagcatag tccttgacta gcacttttta aaacaatagg ccttaattga aaacaactat
     5521 cactatcagc gtttccaaaa ttcatcagtt ctacaaacaa aaatattcag caaggattac
     5581 tttttcgatt catcagttaa aaagtacctt ttttcgaaaa actatgctat acttttaatt
     5641 cgttatttac ggcggaagga gcaaacatgc gatgaatgag aaacaactag aacaaacgca
     5701 cgtggatgaa acgatcgaac taatccagat cgaacaaaat atgctggata caaaacaaca
     5761 agaattgact caggaaatga atcattcgac aaaagacaca gctaatcaca agattcgagc
     5821 tggttccaat gaagcttttt atgaatctgc tgttgaatat cgccaacatg agcaggaatt
     5881 gcttttgaaa taccatactc ttgaagcaca gcaaaaacgc ctgcaaacgt tgtctgtcat
     5941 gaaagatagt ccttattttg cccgtatcga ctttaaagaa gaccgtgaaa cagaaacatt
     6001 atatctaggt atcgcttctt taagagatct ggcagaagaa acaatcgtta ttgactggcg
     6061 cgcaccaatt gccaatcttt attatgaagg tgagattggt cccgcatttt atgaaactga
     6121 aacagataga atagatgtcg atctgcagtt gaaacgacaa tttaaaatcc aagaaggacg
     6181 tattttatct atggtagata cgtcggaagt aatcaatgat gactttttgc tagagatatt
     6241 ggatgaatca tcaagcaacc atatgaaaaa catcgtctct acgatacaaa aagcacaaaa
     6301 tgcaatcatt cgggacacaa caagtaaagt aatgctgatt gaaggaatcg ccggaagtgg
     6361 aaagacatcc gctttgcttc aacgtattgc ttttctgttg tatcataatc gcaagtggct
     6421 cgaggctgaa aacgttcttc tattttcacc caaccatttg ttttctgatt acatctcgac
     6481 tgtattgcct tcattaggtg aaagcggcgt gcctacacag acattcaaaa attatttggt
     6541 gcagctgctg ccagagtttt ctttactaga tgaacagcaa caagaaagtg gttttttgct
     6601 aggggaaaaa gatccgatac aagtgatgaa aagcggattg accttagtcg atcagattga
     6661 tcgctatatc caaggcatca caaactacgg tcccttgttc cgtgatatga aaataaatgg
     6721 ccgtacgatc ctatcaaagg aatcgattcg ccaatggtat aaagaaacaa atgaacaatt
     6781 acctttacat catagacttt ctctattaca aacgaagctc ctgaaaaaat taggcggtct
     6841 gcaaaaagac gaaacacgtc agcaatgggt caaagatctg gcggaagaac agctccaaga
     6901 actatacgca acagatccaa atcttgaata tacagaacaa aaggagcgtt cattacgtaa
     6961 aaaactggcc aaccaaatcg tacgtaaaag attccgtcga atccatcgag ggatcatgaa
     7021 ttatcaattt gtcaatataa cgaaacaata tctccacttt ctacaaactg tgccactttc
     7081 tcttctaaca cgacataaaa tcagcgagac caggtggcag gaacatttga caactgttcg
     7141 tacacacttg cgtcaaagag aattgcgtca agaggatgct gtactattct ttttactgat
     7201 gcgccgaaca tatccagtga cggttacaca caaagctcgc tatatcttta ttgatgaaat
     7261 gcaggatttc gcaccatcac aagtggcatt gctgcaagcc ttgttcccaa aagcaaattt
     7321 gactttctgt ggagatctaa atcaaaatgt ctttggaaat gaaacgatcg ttggatcatt
     7381 ggaagacctt ttcgtggacc gtgaagtcac tcgtttccaa ttaacgacaa gctatcgctc
     7441 cacaaaagaa atcactgatt ttgctaatca ttttattgtg aaagaacatc aagtagaaac
     7501 aacagcaaga aaaggagacc ttcctttgct catccaagga acaacagatg atatcaaatt
     7561 gaattggtta gcagatacca ttcgaacgac tcagggaaaa gcccggtatt ggcgtacagc
     7621 aatcatagct aaaacacaag aagaatgcga agctctttat gctcaactgc cagacgagtt
     7681 gaaacaacaa gtccagctga ttttaaatga gagtgacttt atgaagcgtt ccattatttt
     7741 acttccagcc tttttagcaa aaggtctgga gtttgaccga gttttcttgt gggatgtaga
     7801 tgcagaacat ttttcttctc agcaagacaa attgatcctt tacaccatgt gtacacgtgc
     7861 gatgcatgaa ttgacccttt ttacctccaa taatgaaagt cctttgttaa acaatatgga
     7921 tatttcatct tatgagaaaa aagtactgta agtaaaaaga caactgctat cattaatgtt
     7981 agcagttgtc tttttattta caataataat tgcagaaaaa gtaattcaat catttaaggt
     8041 catttattct atatataaat ccaaatctgt ttcaggatat tttaatttga caagcgaaat
     8101 aatcattttc agttcttcca tgttttctgg atattctggg tcaaatacct tgctatgacg
     8161 gccaatcccg ccattgtcga tcaatcggta aattcgattc cattcaatga attggtcaat
     8221 tgattggaaa ttgctgattg gatagccgcc acaatccaaa atctctgata cacgaaatgc
     8281 taggtatgca ctatcgatca ctttattttt tttcgtgtct atcttctcat ttctttcgat
     8341 aagaattttt tcaggacgat gtttcaagct ccactctaat agtagaaaga aagcctccat
     8401 ccgatactct tcttcaaata accgaaaggc tgaatcagaa cgacgaaaaa gcagcggaat
     8461 cagataattt tgtctataaa tcagcattgg tgcgcggtcc accatacact ctaaataacg
     8521 gttcagatac cctgtaccga catagtttcc taatcgatag ccttcaacgc cgaatcttgc
     8581 gtatttttgc gctaattttg aacaatcagt tacgttcaca gctaactctt ctactttgcg
     8641 gtaaccgctt aagatacgtt caaaaggttc taaagtgatt tttgcttcca tattcttccc
     8701 cgtccatctt ccacatactt catatcattt cacatgatac ttatgctctc atcataccac
     8761 aggttgaatt agaaaagaaa ataaatcaca caaaaaagca agacaatctg ttagtgagat
     8821 tgtcttgctt ttcgaaaaag actgaatact tttcgttaaa actggttgct tagtcttcta
     8881 atgccacatt atggaacaca tgctgtacat cttctagatc ttccagtgca tcaatcattt
     8941 tttcaaatgt ttcttgatct tctggagata gtgttacctc gttttgaggg atcatttgga
     9001 tctcagcgat tgaaaaatca gtgattcctt tttcttttaa tgcttcttgt atactatgga
     9061 aatccgctac ttcaccgtaa acgatgattt gtccttcttc ttccattaca tcgcgaacat
     9121 cgatgtcttt ttccattagg tattcaagga tctcgtcagc gtcttctcct gcaaaagcaa
     9181 agattgctgt attgtcaaac atgtaagaaa ccgctccgga aacacccatg ttcccgccat
     9241 ttttcccaaa tgctgcccgt acgtctgctg ctgttcgatt cacattgttc gtcaatgtat
     9301 caacaatcac cattgagccg cttggtccaa atccttcata gcgcaattca gagtatgttt
     9361 catctcctgc accttttgct ttttcgattg ctcggtcaat aatatgtttt ggtacattat
     9421 aagttttagc gcgatcaatg acgaaacgta gtttttggtt tgcatgcgga tcaggatcac
     9481 ctgattttgc tgccgcgtag atttcaatcc caaattttgc ataaatccgg ctattattag
     9541 catctttagc agttttcttt gctacgatat ttgcccattt acgtcccata ttttcacttc
     9601 gctttctgat ttgatagttt cataacgcaa aaacgtcctg ttccattata cttgtgaatc
     9661 acgattctgt gaagcttttt ttctttcttc cttcattctt ctcattttta gtcaattatc
     9721 tatactcgga ttgggatttg cccgaaattc tgttccggaa tattgcctcc caattgatag
     9781 atttgatcac ttctaactaa cagttccgct tcttgtgcct ctttttttcc gattcgggaa
     9841 taaatagaaa tctctttttt ttcttttaag aatcttcttc cagcatcggt aaatccaagt
     9901 agtcgaagat aatttttatt ttgttggaca ggaatctctt gctttttgat attcagcaag
     9961 acataacaag ataatcgttg gatccgtgtc catgtatatc tttttgtttt tacctttgac
    10021 acaaaatcct caaaactatc agcagttgca gctgctgttt tcatgcgcga ttctattcct
    10081 tcggtcatct gatagatatc tgtcagttcc agcaaagtag aagataacaa ccgataacgc
    10141 aaatacggcc aataagattc ccaagtctgc agcgaacaag ttgaaagatc ttcttctgtc
    10201 tgaggcggca caagtccagc tattcttttt ccttcttcta acgcatggcg aatggctgtt
    10261 gcactggcta tcctctgatc tgtgatgatt ttttcatgat agcctgcact tttacgtcgg
    10321 atcggatgta attccatagg gtggacatac ttggcatttt cctttgcata acttaatccc
    10381 aagatatgat ttggcgaaga aaaatcaagc gtaatatcgg gatacagact gcgaaaaacc
    10441 tcagtcattt tttgcggata actatacgtt tgatcagaca gttcttgaaa tgcctcttct
    10501 atcctatctt gattctcttg gacaaagcgt ccgaaactgc tgtaatcaaa cgaagtctct
    10561 tcttctgttc caaaacacaa actgtcacag tccagtgttt gcaagatttt tactgcacct
    10621 ttagcaaaat agtcagctga ctgaaccgcc cattcgacgg gaagctccac tactaaatcc
    10681 acaccatttt gtaaagcttc attcgcgcga tgccatttat cgatgatagc cggttcgcct
    10741 ctttgcaaaa aattcccgct cattacagca atgacgacct ctgctcctgt tatttttcgt
    10801 gccatttcca catgatagcg atgtccattg tgaaaaggat tgtactctac gataatcccg
    10861 cagcttttca tgcgcatcct ccttcatagt tatcgataaa aaagaaatag agacaagtaa
    10921 aaaaaggcaa aaatcggaaa aaatacccga actatataaa ctattctcgc aaacacaata
    10981 cttctgcgac gaaaagctgc actgcaagag caatgcctat atcgttcgga tatataattt
    11041 atgttgaaga tttattcttt tcttgttaac tcgagcaggc aaaaccgcta gtctttgtat
    11101 gctacaaaga accagcgctt tgatttctct gatgctgctt cgtctgtaaa atcagaaaat
    11161 gcttcgactt tcgaaaagcc gctgttttcc agcattctta aataactttc caatggatag
    11221 gtacgctctt gatgtagttc atcttcacga ataaatcgac cagacccttc ttgttcttca
    11281 acgaaaaagg taagaaaatg ttcgatgctg tgtttctcgc ttcctggata actatcccac
    11341 aaaaaagcaa aattatcccc ttgataatga tagctatatt ctggaaaaac ctcatctact
    11401 tgataggtgg agtgtacgtc aaataaaaat cggccatttt cttctaacgc ttgatagact
    11461 tcatcaaaca cttgctgtac ctcttgtcta tttttcatat agcacagcga atcagaaaaa
    11521 caggtaattg cctgatattg tccgatttct gataaatcga gcatattgcc ttccacaaat
    11581 tggatcgatg cgtcttcttc atatgctcgc tggctggcaa tcatcaacat ctcttctgaa
    11641 aggtctaacc ctgtcacttt atatccatct tttgcaaagg caaccgctaa tgctccagta
    11701 ccgcatgcca gttccaaaat attttttgtg tcttcttgta aatgacgttt cgaaaaagct
    11761 aaccattgct gataaagtgt ttcgtccatc acttcatcgt aaatgaaagc aaatgtttca
    11821 taagccatat gttaatccaa ccattcacta agatcgacta gcggagcatc tgaccatagt
    11881 ttttccagat tatagaaatt tcgttctggc gcatggaaaa catgtacgat cacatctcca
    11941 agatcgatca atacccattt tccgccttct tttccttcaa tacgttttac ttcatatttg
    12001 ttttcttctt ctttatcaat gatttcttct gtaattgcgt tgatttgacg ttcgctattt
    12061 gctgaacaga tcatgaaata atctgccaac aaggaaacat ttcgaacgtc taaagcgata
    12121 atgtcttctg cccgttttga atctgctgct tcaatcgcaa tttttaattg ttctttacta
    12181 tctatgatga tttcctccta atatgagcag cttatttttt tgctacccag taattatatg
    12241 tttcgattgt ttttggataa atctgttgtt cttgcgcaag caaatgggcc aatgtatgtt
    12301 ttgtttcaaa tgctacagct tcgtctagat cagcccatgc aatggctcgt gcatcttgta
    12361 ccccaggaaa atctcgacct ggttcaatat agtctgctac ataaatgatt ttgtcaagga
    12421 gactcatctt agcagcccca gtcgtatgca cccggattgc atgaagaatc tctgcatcgg
    12481 tgattcctaa ttcccgctct acaaacgaag cgccaacaag accatgccag attgcattat
    12541 tataattcaa taactccgga tcaaaaccgt ctcttacgat taccattttg aactcctcat
    12601 ctggtcgttc ttttgcataa tcatgtgtca atgcagcaat actagctttt tcaggagaag
    12661 caccgtattt tttggcaaga gccacggctg tttcttctac tccaagcaca tgcttgaagc
    12721 gttgttcgct cattctcatc tgtatttttt gcatcaggtt ttctctagaa taagcagtat
    12781 attcattact atagtccata ttcatacaac ccttcatttt gaatataatc aattacttta
    12841 tctggaacaa ggtagcggat agaacagcct tctttgatct tttgacgtat tttcgtggaa
    12901 ctgatgtcga tctcaggtac atctacccaa attacaggat atggagtatc cgttgtgtat
    12961 cctggtcgac gtatacccac aaagttgacc atagaagtca gctcatcgat tttataccat
    13021 tttggcaaat attctaccat atccccaccg ataataaagt aataatctgt atccggattg
    13081 ttttgcgtca attccttcat agtatcatag gtgtaacttt tcccaccacg agctaattca
    13141 atcgtttcaa tctgcaaaaa aggattgtct tccaccgcta attccaacat gttgagtcga
    13201 tgttttgcat caatcgtctg tttctcatca acatgaggtg gctgataaga aggcatcaaa
    13261 aatacgcggt caagacctaa attccggcca gcttgttcag ccatcactaa atgtgcaagg
    13321 tgaacgggat tgaatgttcc gcccaagatc cctacttgct ttttcttctc taagaattga
    13381 ggcatttctt caggaaataa ttgtgaacga acaaatgtct tagcttgcgt attcatcatg
    13441 gtcactcctt atattgcttt tacttctttt gatagccttt gatacttttc ttttgtggaa
    13501 ggtttgtata atacaataac acgtccaatg atttggacga tttcgcaatc tatttctttt
    13561 tctaatactt gagctgcttc ttctgcaatc tcatctgtat tttgaagtaa cgatactttg
    13621 atcagttctc ttttttctaa agcttcttca atttgaacga tcattgctga attgatccca
    13681 ccttttccga tttgaaaaat cggctgaaga tgatgcgctt tgctacgtaa aaaacgcttt
    13741 tgttttcctc ttaaactcat aattttcctt cttccttaaa tcaatgcttt gcgtttcaat
    13801 acatctacac cctttggcgc ccagcccgca attactactg gcgctgttac agtgatccag
    13861 cctagaccgg caaaaacgat gtctgttttt tctttcacag aaaactcaaa acgaacaagc
    13921 tccggaaatg cctcgacttc atcaggacga ggaggctgta ataatccacc tacatgtttt
    13981 tgataaaatt cgtctgcttt ttccagtttc gttcgatgaa tatttacatc atttgacaca
    14041 taagcaataa atgaagcacg attgccgctg ataaaatcaa atcttgcaag tccgcccaag
    14101 aaaagtgttt gcccttcatt cagctgataa actttaggtt tgatttcttt taacggtgca
    14161 atgatccgca aatctttttt acctaagtag tgcgccattt gatggcgatg gataattccc
    14221 ggtgtatcaa tcaaaaaatg cccgtcatct aaaggaatct cgattttatc caaggtcgtt
    14281 cctggaaact gcgaagttgt gattacatct tgtactcccg ctgtattttt gatgatttga
    14341 ttgataagcg tcgattttcc gacatttgtt actccgacga tatagacatc ccgtccatcg
    14401 cggtattctt cgattttttc taatagttcc gtcatctcat gagatttctt agcactagtt
    14461 aataatacat ctactggacg aattcctgct tcgtaagcac gttccttcat ccattgtgtt
    14521 aatttagttt ttttcaatga tttaggtaat atatccactt tgttcccaac taaaagtact
    14581 ggattgtcac cgacaaaacg gtgtagtcct gggattagtg aaccattgaa gtcaaaaata
    14641 tccaccacat tgacgatcaa tgcatctttt tgccctaatt cattcagtaa gcgcaaaaag
    14701 tcgtcatccg tcaatgagac atcttgggtc tcattataat ggcgtaatct gaaacaacgc
    14761 tgacaataga cttccccgga agctaaacct ttttccaaag ccgtttgcgg cgtgtatcct
    14821 aattcaccgg gtttgtttgt ttgtataacg gcaccacagc cgatacattg taattcttct
    14881 gtcattcgat tccacctcgc cagcccatat cagggtgttt tgctaataga taggccataa
    14941 ttcttttttc ccaaaaacga ttaaattgtg tcttccaact atctgttgcg ataatgggtt
    15001 ttacaaggat gctacgtatc cctgcacgat tggctccacg tatatcagtc ataatctgat
    15061 cgcctaccat tactatctca tcatctgcta aatccaattg tttctttgct atgttgatcc
    15121 ctcttgctaa aggtttcatt gctcgtgcaa catacaaaag atcaaatttt tcaatcgctc
    15181 gcgcgacacg ttttgaatta ttgtttgaaa caacaacaac agggattcct gcatttttca
    15241 tttctaaaat ccaagtaagc aactcttctg ttccatctgg attattccat gcaatcaacg
    15301 tattgtctaa atcggtcaat actgctttga tgcctagatt ctttaattgg gcaggtgtaa
    15361 tctgatagat ggcttctacc atccatgttg gtttgtaatt tgaaaacatg ctgtctcctc
    15421 atctgcaaaa aatgaaggag cacataaagt actcctcaac cccgtattat actgcatatc
    15481 agcaaaaaaa actacctcta tactcgttcg tctttcagaa aaagcatttc tttacaaaat
    15541 gaccaaaaat aaagattgat cacagaaaaa tttagaaaca aaaaacaact aatattggcg
    15601 gaacctcttg tatcgttttt ccagtaattt atgctgatct aatcgaacaa gttccgtcaa
    15661 tctttcaatc aacgcttttt tcataatgtg tgcgacttta tatcgtggca actgctcgcc
    15721 gttgaacgtt tcaggaataa ctcgatcaac gattcctaac tcgcgtagtt ctggcgcagt
    15781 aattttcatc aactcagctg cttctgcggc gcgactaccg tctttccaca aaatcgacgc
    15841 aaatccttct ggagaaagca cagcataaat cgtttcttcc agcatccaga cttcatccgc
    15901 taaacctaga gcaagggcac cgccacttcc accttcacca atgatgatgg cgatgatcgg
    15961 tacctttaaa tcagacattt cgagcagatt tctggcaata gcctctcctt cgccgcgctc
    16021 ttctgctcct acaccgcaat atgcacctgc tgtattgatc aaggtaatca ccggtctatt
    16081 gaacttttcc gcttgtttca tcagtcgtaa agcttttcga tagccttcag gatggggaga
    16141 accaaaattt ctgcggatat tttcctgcag atcccgtcct ttttgaatac cgatcactgt
    16201 taccggtttg ccatctaatc gagcgattcc accaacaatc gcttcgtcat ctgcaaataa
    16261 acgatcacca tggcattcct cgaaagaatc gaagatctct tcaaaaaaat ccaagcttgt
    16321 ccatcgttct ttagctcttg ctaactgaac gacatcatgt gctgtcttat ccacgatcta
    16381 tccatccttt ctgtgtatgc aattcaagaa gcgtatggat tttctgtttc aattccatgc
    16441 ggggaacaat ctgatcgaca aaaccatgag ataataagaa ttcagccttt tggaaatctt
    16501 ctggaagttc ctgcttgatc gtctgttcga tgacgcgtct tccagcaaaa ccgatcaagc
    16561 tttggggttc tgctagaata atatcgcctt ccattgcaaa actggcagtt actcctccgg
    16621 tcgtcgggtc cgttaaaaca gttagataaa aaagaccttc attgctatgc cgtttgacag
    16681 cagcagagat ttttgccatc tgcattagag aaaagattcc ttcttgcatc cgtgcgccac
    16741 ctgaagctgt gaacaagacg actggaagac tttcctttgt tgctcgttcg aataatctgg
    16801 tgatcttttc tccgacaatc gttcccatac ttcccatgat aaaattagga tccatcactc
    16861 caataatgaa gggaatcccc tgaatggttg ctttaccagt gaggactgct tcatgaagtc
    16921 ctgttttatc ttgcattttt ttaatttttt ccgtatattc gggaaatgct agcggatctt
    16981 tggttacaag atccgtatcc cattcttcaa aacttttttc atcaataatc aaagctagac
    17041 gctgccatgc accgattcga aaagcgtatc cgcaatgagg gcatactttt tcttcaccga
    17101 tgtctttcgt ataaaggata tgtttgcaat ttggacactt tgcccacatg ttatcaggaa
    17161 cagatggcga gttagcaggt ttgctctctc tattaggatt gatccgaata tatttctttt
    17221 tcttaaacag agccatctat gcgcctccta tctccgtttc tggtgtccaa ttcggtaaaa
    17281 attcttcttg taaaaatgct gtgctgtaat cacctgctat gactgcagga tgactaatca
    17341 aatccatctg aaattctgcg ttcgtgatga ttccttctgt gataaattca cttaaggctc
    17401 gctgcatctt cattaatgct tcaaaacgcg tatttccatg gacgattatt tttgcaatca
    17461 ttgaatcata atatggcggg atcgtatatc ccgggtaaac tgcactgtct actcgcagtc
    17521 ccatcccacc tgctggaagc agtaagtttt ggatcttccc tggagaagga gcaaaatgga
    17581 aagcaggatt ttctgcatta atccggcatt cgattgcgtg tccttggaat actacttctt
    17641 cttgacacac attcaaaggc tcaccggctg ctatctccac ctgttttttt actaaatcga
    17701 ttcctgtgac catttctgtt actggatgtt ccacttggat tcgagtattc atttccatga
    17761 aataaaaatc gccttcttca tccatcagaa actcgatcgt tccggcattt tcataattga
    17821 ctgctttagc tgctcgaaca gcagcgtctc ctagtgcttc tctttttgtt tgtgagatca
    17881 ctacagaagg agattcttcc agtacttttt gattgttgcg ttgtaaagaa caatctcgct
    17941 cgcctaaatg aatgacatga ccaaatcgat cacctaagat ctgaacttct atatggcgag
    18001 caggataaat gattttttcc aaatacatat catcatttcc aaatgccgct gctgcttctt
    18061 gctgagctga agaaaaatgc tgtgggagct cttcttttga ttgaactttc cgaatgcctt
    18121 tcccgccacc acctgcagct gctttcagca tcactggata accaattctg tctgctattt
    18181 ccaatgcttc ttctactgta gataatacac cagtacttcc tggaatgact gggacatttg
    18241 cttcttgcat caattgacgc gcattgatct tatttcccat tgcatcgatc gttgcacttt
    18301 taggaccaat aaatgtgata ttgcactctt cacacatgga ggcaaatcgg ctattttcag
    18361 ataaaaaacc aaatcctgga tgaattgctt cggcttttgt cacgattgca gcgctcagta
    18421 cttcctgaac attcagatat gaatcaacgg cttttgccgg gccaatgcag attgcttcat
    18481 ctgctaactg tgtatgaagt gcttcggcat ctgcttctga atatatcgct acggtttgga
    18541 tccctagttc gcggcatgca cgaatgatac gtacagcgat ttcaccgcgg ttagctatca
    18601 atactttaga aaacatattt cacctatcca atcataaagg ttaattccgc ttcggctact
    18661 tttttaccgt ctactttagc gattcctttg cctattccgg ctgaagcttt cactttcaat
    18721 atctcaactt caaggtataa ggtatctccc ggtgtaactt tcttacggaa ttttgctttg
    18781 tccaatccgc cgaaataagc cgtctttccc ttgaattgtt caagagaaag taatgcaact
    18841 gctcctgctt gagccattgc ttcaacaatc aatacccctg gcataacagg ttcttctgga
    18901 aaatgtcctt gaaaaaaggg ctcattgatc gttacatttt tcttagcaac gatccgttct
    18961 ccttcaacca tttcttccac tcgatcaatc aaaagcattg gataacgatg tggaatgatt
    19021 tcttttattt cttgtatgtt cattgttttc cctctttcct gctttgctta tttttgctga
    19081 atcctaaaga gtggctgtcc atattcgaca actgactcgt tttctacaag gatttctgtg
    19141 atcactccgt cggcctcact agttatctca ttcatcagtt tcatcgcttc aataatgcag
    19201 ataacttctc ctttggcaac ttgatcacct acttttttga aagctggttt gtcgggcgct
    19261 ggttgcagat aaacgattcc cacgattggc gaaacaacct cgattccatc aaatactgcc
    19321 gattcttttt ctttcattat ttctggagca gttgttgctt gttcaggtat gacattgact
    19381 ggctccgaaa ctggcaacgt ttcgtttgtt tgaaccatat tcatgcctcg acttgtttta
    19441 tttttattca tatacaattc aaattgacct tcacgcaaat cgaattccgt tagcgaggat
    19501 tgatcaaatt gactgactaa ttctctgatt tcattgatat ccaaaattat tcctcccagc
    19561 gtttcatgca cagaaccgca ttatgtccgc caaaccctaa tgaattactc attgcataag
    19621 taaaacttgc aggtttgctt tcgtttttga caactgtcaa gtcaatctca ggatcttgtt
    19681 tttctacatt gatcgtaggt gggataaatt gatgttctaa tgccagcaaa gttgccaagg
    19741 cttcgatccc gccggctgct cccaataaat gtccagtcat cgatttcgtg ctgctgacgt
    19801 aagtatctct gaaattttca cctaatgcga tttggattgc ttttgcttct gcctggtcat
    19861 tggctggtgt acttgttccg tgagcattga tatatccgac ttgttccggc tgtacaccag
    19921 cttcttccat cgcaagcttc attgctttag atgcaccaga accatctgga gtaggagctg
    19981 tcatatggta agcgtcacag tttgcaccgt atccaacgat ttctccatag attttggcac
    20041 cgcgagcttg tgcatgttct aaagattcaa gaactagaac gcctgctcct tcacccatca
    20101 caaaaccatt ccgattttcg tcaaacggaa tcgaaccacg attaggatca gttgattctg
    20161 agagtgctgt taaagctgca aatccagcaa tccccatctc acaaatcgtt gcttctgttc
    20221 ctccagcaag aatgacatca gaatagccat gtttgatgtt acggaatgct tccccaattg
    20281 aattcgttcc gctagcacaa gctgttacga tagctgtaca aatacctttt gcacctacac
    20341 gcaaagcaat atttccagct gccatgttgg caatcgccat tggtacgaac attggagaaa
    20401 ctcgttttgc acctttttca tgtagacgaa taacttggtt ttcgattgtt ggaagaccac
    20461 cgatcccaga tccgatgatg acgccaaacc ggtcttgatt cattttttct ttatctaaac
    20521 cgctcatctc cattgcttct aaagcagcgt agattccata gatcgaaaac atatccattc
    20581 gtttgctatc ttttttaata aaatatttat cgtaagggaa atctttgact tcacccgcta
    20641 aggtaatccc tgtttctgaa gcatcaaatt tagtgatcgg tgcgatgcca ttcgtcccct
    20701 cttttaagct attcaaaaag ctgtctgcgt catttccaat aggtgaagtg actccatagc
    20761 cagtaattac cactcgattc atttgtttgc tctccttttc ttatccgtgc atgaccaatc
    20821 cgccatcgac attgatgact tgtccggtga tatatggatt ttgtgctaag aaaactgctg
    20881 tttgtgcaat atcttctact tgtccgaaac gctgcatcgg aatttgcttt tccgcttgtt
    20941 ccttgacttt gtctgctaaa acttccgtca tatcagttgt gatgaatcct ggcgcaatgg
    21001 cattacatgt aatgcctcta gttgcagctt ctcgtgccac agattttgtt aatcctacta
    21061 cgccagcttt actagctgca taatttgctt gaccaatatt tccaatcaac ccagatacac
    21121 tagagagatt aatgatggcc ccttctcgct gcttcatcat ttttttcaat acgtgctgcg
    21181 tcatattgaa ggttccaatc aaattgatat ccagacattt tttgaaatct tctgcatcca
    21241 ttcgcatcac aagtttgtca tttgtgattc cggcattgtt tactaacaca tggatcgatc
    21301 caagcttttc ttctgcttct ttgatcattt gtcccgcttt ctcataatca gagatgtcac
    21361 cggaaactcc tacgcatttt acaccgaatg cttcgatttc ttctatcttt tcttttggaa
    21421 tctctccgcg accattcaaa atgatatttg ctccagcttt tgcaaaagct aaggccatcg
    21481 ctttgccgat tcctcttgta ctacctgtga taaatacatt ttttcctttt acatccataa
    21541 cgttcctcct tatagtattg ctattgtttc atcaaatgtc tgcttattct caacacgcag
    21601 aactggtatt gttttatcga tttttttcat aaatccgctt aatacttttc cggggccgac
    21661 ttcgatgact tgttcgatgc cgattgtttt taacttatgg atactctcat agaaacgaac
    21721 aggttgcatg acttgctgtt caagtagtcc cgcgattgtt tctttcttca ttatttccgt
    21781 tgttgtgttg cttatgatag gaaaagaagg ttcagagaat tgaatctgac ttaggtcctt
    21841 cgccagtttt tttgctgccg gttctaaaat agctgtatga aaaggcccgc tgacatttag
    21901 agggatcatt cttttgaacc ctttttcttt taatagtaaa acagcttcgt ctactgcttt
    21961 ttcttcgcca ccaatcacga tctgctgagg tgtattataa tttgcaggag atacgatgcc
    22021 gtacttgcta gcttcatgac agctttcctc gatcgtttca atcggcgcat tcatcactgc
    22081 aaccattttc ccgcttccag ctggggcagc ttctgtcata taagcgcctc tttttgctac
    22141 taacgcaact gcttcagtga aggatagcgc attactagct actaatgccg aatattctcc
    22201 taaactcagt cctaaagctg catctgggat gattccatgc tccttcaata agcgataata
    22261 cgcgatgctg actgttagaa tagctggctg tgtatattgc gtctgatcca aacgttcatt
    22321 ttctgtaaag caaagttcag ccatatcgta gccgagaatc tcacttgctt catcaaatgt
    22381 ctgctttaca acggcttctt catataaatc ttttcccata ccttgatatt gtgcaccttg
    22441 gccactaaat aagaatgctg ttttcatgtt tttctccaat atatccagaa tatatgtttg
    22501 attcttccta ttcaaaaagg ccgagacatt cctatttcag gaaatgtccc agcccccaac
    22561 ctaattttaa tgattatgca gtttgttttt ctacgtaagt cactaaatct tgaaccgttt
    22621 tgattccgtc ttctgtttcg attttcacgt caaattcatc ttcaatttca ttgatgattt
    22681 ggaataaatc caagctgtca gcttctaagt cttcttggat gtcagtagtc aatttgattt
    22741 cttcagtttc ttttcctaat tcttctgcga tgatttcttg aattttttcg aataccataa
    22801 taatatattc ctccgatatt gtttgctttt tatttttata atttaacagt ctacaactcc
    22861 atgagaatac ttccccatgt taaacctccg ccatagcctg taaatattac tttctgctgt
    22921 tttcctaagg tgatctttcc actagaaact gcttcatcca ataagatagg gatgcttgca
    22981 gcagatgtat tcccatattt atccatattg gtcaggaact tttcttgcgg catctttact
    23041 tttcgggcaa ttttctcaat aattctgagg tttgcctgat gcaaaagcag ataatcaact
    23101 ggtttgtctt tcatgacttc ttggatattg tttgcaacgt ctcgtacggc aaaatcaaaa
    23161 atatctctgc cagtcatttg caaataatac gaaccttctg aatcttctga atagaacgga
    23221 tttttatttt gctggtagcc agcggtcaat gagctacttc tggtaccgtc agctgctaat
    23281 ttttctttca gcaatttttt ctgtggattc gcttctaaga gaatcccacc tgctccatcg
    23341 ccaaacaaca cagcagtcgt acgatcagac caatcgatta gcttagatag tgtttcacca
    23401 ccaatcacca gtcccttagt tgagccgcag cggatcattt tttcagccat gcttaacgca
    23461 taaacaaatc ctgagcacgc agcactgata tcaaaagcga tagcatgagt tgctcccaat
    23521 ttcccttgta cttgtgctgc tacagatggt gtcgtgtaat cgggcgacat tgttgctact
    23581 aaaataaaat ccaaatcttt agggtttaga tttttctgtt ttatcaattt ttccgccact
    23641 aaaatgcata aatcagaagt ctcctgattt gttacacatc ttcgttcacg aatacccgtc
    23701 cttgacgaaa tccattcatc agaggtatcc atcatcttgg aaagatcatt attagtaata
    23761 atcttttcag gaaggacgct ggctgttgca gtaatcattc caaattgttc cattaaatat
    23821 cctcacttat agtcttgcaa gaagtcgtgc aagtttttca gtgcatccag caaggcatgc
    23881 tgttcctccg tagccattcc gtctaagatg ttcttgacca tttcacgatg aaaatgctga
    23941 tggacccgaa atagtaactt tccttttttc gttagtccca actttacaac gcggcggtca
    24001 tcttcactgc ggatacgttc gacatagcct ttttttacta acttgttaat agcagtggtc
    24061 aaggtcccaa cagtaattga tagttctttg gctacttctg aagttgtttt tttcttgtac
    24121 atcccgattg cctcgatcgt gtgcatctct gtgattgaca gatctttgaa ttgagatttt
    24181 ttcagctcag actcttcgat tgtcaaaata tcattgaaga cactaacaag ataatcattt
    24241 actgttttta aatctggttc catgttccac cgtccactaa ttagtttgat tatcaaatct
    24301 tttgatgttc aaactatatc ttaacttttt tcaaaatgca accttaaaag atcatttttt
    24361 tactatatga gcttttttta agattttact catttaaaac aactgataaa tcagcattta
    24421 taatttcttt tattagaaaa atcatctatc tcacatattt tgattatcaa agtattttct
    24481 gtgaacagaa ctatagaatt ccctaaaact tgtccattat ttcaaaattt gttatagtct
    24541 ttttattcaa agcgtaaaag gagatcctat gttaaaagaa aaaatgaaaa ctctccccat
    24601 gctgccgggt gtctatctta tgaaagaccg agatggtaag gtcatctatg ttggtaaagc
    24661 aaaacggctc aaaaatagag taagcagcta ttttcatcag aataaacagc attcaaaaaa
    24721 agtattacgt atgattcatc atataacaga ttttgatttc gtcgtagtag acacggaatt
    24781 agatgcttta ttgctcgagt gtcaattgat ccaacattac cgtccttttt ataaccgaca
    24841 aatgaattat ttcagtaatt ataattatgt acatattacc aataagggat ttgtattaac
    24901 agatactcct acggctcgaa catacgggcc ttttcgtctc tataaaaaaa tgccgtctat
    24961 tttgcgtata atggaagaaa cttatcaaat gccttggttg tctgaaatta gtttgttagc
    25021 tttgcgagtc cagcttcctg acctacagga aatgactttt gaacagaaaa aaaaggaact
    25081 ccaagggctg tttcaaggcc gaaataaaaa gctactgact tacttgaaaa aaagacaaca
    25141 acatttcatc tatcagttga atttcgaaaa agccggtatg cttcaaaaag atatcgaatt
    25201 agttacttat tttattagac ggatccagga acaaaagcag tttttaagaa caccatcgct
    25261 caccttcagc atgccattag cagcagatga gagtcagaaa aagcactacc tcgtttgtta
    25321 tggtcaactt gcagaaacaa tgattacctc tggtgacgtt tctcctgact tctattatga
    25381 aaagaaagaa gctcatttat ctttgaaacg tcaattgtca aaagaagaaa tcgatcctgt
    25441 acaaatcttg atcagttacc gcaaaaaatt agaaaaagaa cagtttgaaa ttgaactgtt
    25501 aaacaaaaaa gaagctgaaa agcaactaaa ttagttgctt ctcggcttct tttaggcatc
    25561 ttcaacttca aatgtcaatt atcctaaaat ttattggatt aagtcataga tttccatcgc
    25621 tacgatatcg atattatcaa attcgtattg ctgatgagta tctgtttcag ttaattcaaa
    25681 tgtatcggtc gctttatcat aagttactgt acacttctct acgccttctt tttcaaaacg
    25741 gcgaacttgc agttcattat ctgctgactc gaccatagcc tccagtcgtt ttatgattgc
    25801 gactaattgt gaatgtgtca tcggaggtcc tccttttctt atttctgtta tattgtatca
    25861 aaagcatagc ctacttgcat tgattttctc taaaaaaact cgttttttat gatttttttt
    25921 ctggtatttt tccttcaggc caccaaagtt tgatcaaagc ttgggttccg tcattctcaa
    25981 aacctttatc tgccaactct tcatatagtt tcaatgcttg ggtagttgct ggcaatacaa
    26041 gatccatttt ttctgcttct tctaatgcaa tctttaaatc tttgataaaa tgtttgacaa
    26101 aaaaaccagg tgtgtaatct tcttttaaaa tacgaggaga ataattgctt aaagaccagt
    26161 tagctgcact tccacctgaa agcgtctcaa tcactttctt taaatcaagt ccgttttttt
    26221 gtgcatagac aagcatttcc gtcattcctg tcatcgtacc tgcaatcatg atctgattag
    26281 ccatttttgt atgctgacct ttcccagcag aaccatgcaa tgtaaatgtc gtaccaaatt
    26341 ctttgaataa aggcagtact tgatcataaa cggcttcttc tccaccgacc atgatcgtca
    26401 gtgtaccatt ctttgctcct aagtcaccac cggataccgg tgcatctaac gcatctgcgc
    26461 ctttttcttt tgctgttttt gcaatttttt ctgccaggct tggtgtactt gtagtcaaat
    26521 caactaaaat atgtcctgag atatctgcag aaaaaatccc cgactgtcca tagtagattt
    26581 cttctacatc tttggggtaa cctaccattg taaagagaat attactttgt tctgctaccg
    26641 cttttggtgt atctgcccag atagctcctt ctgttactaa aggatcagct tttgcttttg
    26701 tccgattata gacagctact tcgtgtcctg cttctagtag atggcgtgcg acagcacttc
    26761 ccatgacgcc tgttccgata aaaccaagtt tcattttttc gacctcctaa aaatcaaaaa
    26821 tccttgcttc tatgctagta tacgctagaa acaaggattt tttcataaaa aatgtttgaa
    26881 ttttatcttt taaatgaatt taattttatt ttgattcgtt caatcgagtc ttcttcttct
    26941 tttcttcgca tctcttcttc atgataaaca accatgtctt gataaaattc gatcatagct
    27001 tcgccgaaat gtgtagatga aatatcataa agtttagctt ctaaaacttt tggatcttta
    27061 ggaacttcac tggaaatata atcaataagt gctggtgcaa agtcttcgtc ggtttcaaaa
    27121 gttttcccta atgaaggatg atcgaacaat cggttcaaat aagcatttcc ttccacgaca
    27181 caaggtgttc cggctgccat cgcttctgta taagtaagcc cttgtgtttc tgaagtagaa
    27241 gcactgacaa aataatctgc cgctttataa taaagtgcta catcattgtt gtccacttct
    27301 cctgtgaact gcacaaattc ttctaactgc agttctgaga tcaattcctc taactcttct
    27361 acataaggtc cttttcctac gataactaat ctggcgttag gataagcgga gatgacctga
    27421 ggaaacccat taatcaaggc ttggatattt ttctcataag aaatcctgct taaagaaaga
    27481 atcatcaaat ggttttcctg aagacctagt gactccctta atttgctgat atcctgctga
    27541 gtgatatcag aacgtttgaa tttttcaatg tcgataccag taggaatcac gcgaagcggt
    27601 gctattacac catagctgcg taatgtatca ataacacgtt cacttggaca aactacacct
    27661 gtcgtatgat ttgcaaataa tctagacaag tattttacat gggattgcct gatcactttt
    27721 cctttaccga tataatgaag gtagtcttca tacatcgtat ggtaagtatg gatcagaggt
    27781 attttcaact tcttagctac catcttccca agtatccctg ctccgaattc tgtatgggta
    27841 tgaataagat ctagttctag ttctttggca accaaataag cataccacat gcctctaaca
    27901 acaactcttc gatccttgaa agaaataaat ggtacacttg gcattcgaat cacatctttt
    27961 tccaacttat ccgcattagg atcggtcgtt gtaaaaatat agacttcatg cccatgtctt
    28021 tctaattctt gttttaatgt tttgatcgat gtagcaactc cgctgacttg cggaaagtag
    28081 gtatcggtaa aaaagccgat tttcatgttt ttcgcctcca aactagtcct tgacctgatt
    28141 tacttttttt aatttgctag agactttttc attcagtaca ctttcgtata catttttaag
    28201 ttcttcaccg attttattga tacttcgctc ttttgctgtt tgataaccgg cttgtgtcgt
    28261 actcggtagt tcttgattgg taatctgttg gatcagtcgg ataaattctt cgtttgtctt
    28321 ccccatatag cagttcttgc tatcttctaa ccagccatta tacactggaa tatctcgaac
    28381 aagtacgttt tgtttgcttg ctaaagcttc taaaacaacg atcccttctg tctcttcata
    28441 agaagggaaa aagaatagat ctgcacctga atacgcacct tctatgatct ctccacgaat
    28501 gtaaccagga aacaggacat tttcaggatg atcttctttt acaattttcc ggatgttccg
    28561 aggaatcgag tacatgggaa catgaccaaa ccaaataaat gtgtattcgg gcatcttctt
    28621 agcaatttct acgaaatcaa tgattccttt acgttcgaaa aacaaaccga cacaaatgat
    28681 tactttttga tccggagaca gtttgaaata ttctctgaac ttttgttctt tcattggatc
    28741 agggtgatat ttctctaagt cgatcccatt ggaaatagct tgaatcggca cacggatacc
    28801 atagctttcc aacaactgtt ttgaataagg tgttggcgtg atcagatagt ccgctttttg
    28861 gtacaatcct accagatatt tttttacgat aggagaaagc tggttcgatc tgataaagga
    28921 atttcggaaa tcttcctctg tagaatgcgc atgatagaca actttttttc cttctcttct
    28981 ggctttattg accatattat gactattgat tccgtatgta ttgatgtgca ggatgtcata
    29041 atcttctttt tcatctagtg tataagagat accgacttcc gtcagagcac gtttttgatg
    29101 atcaagcgca cgcccgattc cagattttgc aagcatcttt tcactttcaa aatataataa
    29161 taccttcacc ttacgtcccc cttcacttat atagtataac atagcctaca aactgtcact
    29221 caaacttaag ccctattttt gtctattctt actgacaaaa acgttttctt aaaaaagaac
    29281 aaaaaaactg gcgtagctct tttacaagcc acaccagctt ttgatacgtt gtttatttta
    29341 catattcatg aacaagttca acgacttctt ccatcatatc gcattctttc aatgcacgat
    29401 cagcaagttc agccattttc gctgtgtcca agcgtttcat taaactacgc gttttaagaa
    29461 tagatgtcgc actcattgag aactcatcta gacccatacc tactagcaat ggaacagctg
    29521 tttgatctcc agccatttct ccacacatac ctgcccattt tccttcagcg tgtgctgcat
    29581 caattacatt tttgatcaaa cgtaaaattg atgggttata tggttggtac aagtaagaaa
    29641 cgcgttcgtt catacggtct gctgccattg tgtattgaat caaatcgttc gtacctacag
    29701 agaagaaatc tacttctttt gcaaacttgt ctgctaagac tgctgctgct ggaatctcga
    29761 tcatgatgcc gacttggatc gtatcagata cttccttgcc ttcacttatc aatttttgtt
    29821 tttcttcttc aaagatcgct tttgctgcgc ggaattcttt gagtgtagct accataggga
    29881 acatgatacg taaattacca tgaacagatg cacgaagcaa tgcacgcatt tgtgtacgga
    29941 acatttcgtc gccttgttca gataaactga tacgcaatgc acgatatcct aagaatggat
    30001 tcatttcatg aggtaattgc agatatggta gttctttatc tccaccgatg tccattgtac
    30061 gaacaactac aggttttcct tccatacctt ctaatacagc tttgtaagct tcatattggt
    30121 catcttctgt tgggaagtct ggagaatcca tatacaggaa ttcagtacgg tacagaccaa
    30181 ctgcttctcc accattatta tggacaccaa ctagatcttt tggtgttccg atgtttgcag
    30241 ctaattcaaa atgcttgccg tcagctgtga cagtttctgc attttttaat ttttcccatt
    30301 ctgctttttg tgctgcgtaa tctgcacctg ctttttcaaa ttcagctttt tgttcatctg
    30361 taggatcgat gattacatcg ccttcgatcc cgttgacagc caaaatatcg ccttctttga
    30421 ctttagcagt aatttctttt gtcccaacga ttgctggaat ttctaaagaa cgtgccatga
    30481 tagcagaatg tgaagtacgt ccaccaatgt ctgttacaaa cgcttttaca aaattgcgat
    30541 ctaattgtgc tgtatcactt ggagtcaagt catgtgcaac aacgaccact tcttcgttga
    30601 tcattgatgg atttggtaaa gtaacgccta ataagtgcgc taaaatacgt ttagcaacgt
    30661 cacgaatatc tgcagcacgc tcttgcatat aagcattatc ttccattgct tcgaacatac
    30721 cgatatacat atccgttact tcttttagcg ctgattcagc atttacgctg ttgtctttaa
    30781 tattttgctt gatttgacct accatttctg gatctgaaag aaccatcaaa tgggcatcaa
    30841 atacttgcgc ttctgcttca cctaagcttt gcgctgcttt ttcacgaatt tgctgcaatt
    30901 cttcagtaga tttagctaat gcagcatcca aacgagcttc ttcagccgca gtatcttcta
    30961 ctgttgcctt actgaatgtt aaatccggtt gaactagcag gtaagctttt gcaacggcta
    31021 caccgtcact agcggcaatc ccttttagca tttcaaccat tattcagata agccttcttt
    31081 cttcattgtt tcaacgattg ctgccattgc atcagcttcg tcagcacctt ctgcagtaat
    31141 agtaacatca gaaccttgac ctacacctaa agacataacg cccatgattg atttcaagtt
    31201 tactgattta cctttatact ctaagtttac atcagagtta aatttgcttg ctgtttgtac
    31261 taatagtgta gctggacgag cgtggatccc agtttctgct actacgtgaa attctttctt
    31321 ttccatatta atcggtctcc tttaagtgag tgttgttttt atgtgagggt tttctttttt
    31381 agtaattcag agaatcctaa caaatgccac cctttcatct gtaaagatta acattttttt
    31441 tcgttagata caacagtttt cattcaattt cagataaaag tattcaaatt attccggatt
    31501 ctttttcatc cttttcttca cattttataa caaacgtgtt tatttccttt ttcttgtcgc
    31561 tttctcttct cctgacgttt atcattcttt cctttgaccc tctttgtttt catatgaaac
    31621 gaattacttg cttccctttt tatttttagt ataataagag tcaaaggtca ggaatggtca
    31681 atagagattt caccttttct acctcataaa tctcttaaaa aactaggggt tattctttta
    31741 cctcatgaaa aacgagatgt aaaatatgga tgtacccatt tttgtgaaag gacgtgaatg
    31801 attcatgctt tgtcaaaact gcggcaagaa tgaggcaacg attcacttgt atgccactgt
    31861 caatggtcag cggacacaac tcgattactg tcagagctgt tatcaaaaaa tcaaaaatca
    31921 acaaaatgga ggtctgacta atatggccca aaatgatcca tttggatttg gcagtttgga
    31981 cgatcttttc cgttccatgt ctcgccaaat gcaacagcaa ggaaattatg agcaaacacc
    32041 accaacacaa tttggcggaa acaacaactt caatggtggt cagccacctc aaggcaatac
    32101 agaaggttta ttgggagaat acggaatcaa tatcacagaa caagcacgac aaggtgatat
    32161 cgatcctgtg atcggacgcg atgacgaaat caaacgagtc attgaaattt taaatcgccg
    32221 aaccaagaac aatcctgtct tgattggaga accaggtgtt ggtaaaacag cagttgttga
    32281 aggtttagca caaaaaatcg tagatggtga tgtaccgcaa aaattaatgg acaaagaagt
    32341 cattcgttta gatgtcgtat ctttagtcca aggtactggt atacgaggac aatttgaaga
    32401 acgtatgcaa aaattgattg aagagatccg tcaagcagaa aatgtgatcc tattcataga
    32461 tgaagttcac gaaatcgtcg gtgctggttc tgctggtgat ggaaatatgg atgctggtaa
    32521 tattttaaaa ccagctttag ctcgaggaga attgcaaatg gttggtgcta ctaccttaaa
    32581 tgagtaccgc atcatcgaaa aagacgctgc tttagaacgt cgtatgcaac ctgtacgggt
    32641 agatgaacca actgtcgaag aaacgatcag tattttgaaa ggtttgcaaa aacgttatga
    32701 agactatcat catgtaaaat atactgatga ggccatcgaa gcagccgcaa ctttatccaa
    32761 tcgttacgtc caagatcgct tcttgccgga taaagccatc gatttgctag atgaaacagg
    32821 ttctaagaaa aacttgacga tccaaatcgt tgatcctaaa acaatcgaga aaaaactgca
    32881 agaagcagaa gaacaaaaag ttttagcttc tcgagaagaa gatttcgaaa aagcagctta
    32941 ttatcgcgat cagatcaata aacttcaaaa aatgaaagaa cgtcagctca ctgaagagga
    33001 aacacctgtg attaccgaaa aagatatgga aaaaatcgtt gaacaacgga caggtattcc
    33061 agtgggtgaa ttaaaagaaa aagaacagac acaactgaaa aacttagcag atgacttgaa
    33121 agctcatgtc atcggacaag ataacgctgt agatcgagta gcgaaagcga ttcgccgaaa
    33181 ccgtgttgga ttaaacaaac agaatcgtcc aatcggctcc ttcttatttg ttggaccaac
    33241 tggtgtaggt aaaacagagc ttgcgaaaca acttgcctac gaactattcg gttcacaaga
    33301 ttcaatgatt cgtttcgata tgtctgaata tatggaaaaa catagtgtct ctaaattgat
    33361 tggttctcct ccaggttatg tcggatacga agaagctggt caattaacag aaaaagtacg
    33421 gagaaatcct tacagtcttg tcttgttaga tgaagtagaa aaagctcatc cagatgtttt
    33481 gcatatgttc ttgcaaatct tagatgatgg tcgattgaca gatgcacaag gaagaacggt
    33541 cagctttaaa gatacgatca tcattatgac aagtaatgcc ggaactggta aagtagaagc
    33601 aaacgttggt tttggtgcgg cacgcgaagg tgttactcgt tctgtattga accaattaaa
    33661 caactacttt acaccagaat ttctgaaccg ttttgacggg atcatcgaat tcagtgcatt
    33721 atcaaaagaa aacttgatga caatcgtcac actaatgcta gacgatgtca accaaatgct
    33781 ggcagcacag caacttcaca tcgaagttcc tacgaatgtc aaagaaaaat tagttgactt
    33841 aggctatgat ccatctatgg gtgctcgtcc tcttcgacgc acgatccaag aacaaatcga
    33901 agatggtatc gctgaatttt atcttgatca cccttctatc catgagttga aagcaaaact
    33961 ggataaagat ggaaaaatca tcgttacttc taaaccagaa cgtttggcta aagaatcagc
    34021 cgaagaaacg gctgaataaa tccagtttta tagcgtgaga cggtatttct ttgagaaatg
    34081 ccgtctcatt cttttttcag aaaagtcaaa atactgttca ttttataaaa aagaaattat
    34141 aataagagaa acaagcaatt aaaaatacat aaaagaggtg agcgccatga aattggtaaa
    34201 tgtaacaaac agccattccc gtcttgtatt aaaccagctt gaaaacactg atgcccatct
    34261 agtcaaggtc tacacagccg gaaataccac tattgtctac actgaagccc ctgaacataa
    34321 tgaaattctg ctgatcaatg acaaacgtaa aatccagccg aaagaaatcg aagatgctaa
    34381 aaattatttc ttagataaaa tcaaagacgc cgtttaccac gaggatgaaa tcaaagtaat
    34441 cgaattggca ggccttgttg aaatctcgat tccaaaacat gaattaggcg ctacattagc
    34501 cgtgtaaaca aattttgaac ataataatta aagagcgtgg gacaaaagta aagaacactt
    34561 ttgtctcacg ctctaaacac gtataaacgg cgaaagcaga agcaactcct tcggaaataa
    34621 gctgaaattc acgaaaattg cttttcaaat ttttgtgaat tccagcttat ttcttggagt
    34681 taaacgcttc tgtctcagcc tctttttctt tctagctttt tgatttttct cttttctttt
    34741 gtacttttct cttttcattt tcagttctac gcgtgtcttt atttttaact ttttcctctt
    34801 tatggatgat tgatcgtact ttttgtgcaa tttgctcgtt tttgtcccag tcttttacat
    34861 ctaataatcg acataatcgt aacatctctt cttttttctg tttttttctt tcacgtcttt
    34921 gccattctgt ttccatgtgt cacactctcc tttctttaat catatgtacg caaaataatt
    34981 tttatatttt tttgattaga catttctatg attttaatat agtaaaaaga gccgtcacgg
    35041 aaaatccgtc acggctctaa acaaaatatg agaggctgtt tttgtttggc tattcttatt
    35101 acttgatgca gggcagcttg tgtcaagact tctttacatc aaacttttta attttacatt
    35161 gggatattta tccgcaaacc agcgttctgc aaattggttc tcgaataaga acaacggttg
    35221 gtcgaaacgg tcacgagcca agatattgcg acttgaactc atcttctcat ccaaatcttc
    35281 tggatcgatc cagcgagcga ttttgtgtcc cattggagac atgattactt cggcgttata
    35341 ctcatttaac atacgatatt ggaatacttc gaattgtagc tgaccaacag ctccaatgat
    35401 atattcttcc gttagatatg ttttataaag ctgaatcgct ccttcttgaa ctaattgata
    35461 gattcctttg tggaaggatt tttgtttcat gacatttttt gcagtcactt tcataaacag
    35521 ctctggagta aatgaaggga gttcttcata agcaactttt agttttcctt cgaacaatgt
    35581 atccccaatc tgataattgc ctgtatcata tacaccgatg atatcgcctg ctactgcttt
    35641 ttcgacgttt tctctcgaat ctgccataaa ttgtgtgaca ttgcttaatt tcagtttttt
    35701 atttgtacgt tccaaccaga catccattcc tcgttcgaat gttccagaac agattcggac
    35761 aaaagcgatt cggtcacgat gggctggatt catatttgct tggatcttga atacgaaacc
    35821 tgaaaattct tcctcataag gacttaccat ctgatcatct tgtgttttgt gtccataagg
    35881 agctggtgcc aattcaacga aagtctctaa aaaagtctgt acaccgaagt tagtcaatgc
    35941 agaaccaaaa aatactggtg tctgatcgcc acgagcaatt ttttcttgat taaatgcatc
    36001 tccagcctct ttgattagtt ctacttcttc taagacttgt tcatataagg aattttcagt
    36061 tagaggatga ttttcgggaa gcagtccatc ttcatccaat tctactaatc gttcatcctg
    36121 ataattttcc ggacgataaa actctacacg attatggtag atatcataaa gaccttctag
    36181 ccctttaccc ataccgattg gccaattcat cggataagat tcgatatcta atagctcttc
    36241 taattcttct aacaattcca atggttcacg accatcacga tctagtttgt tgataaaagt
    36301 aaatatcggg atgccacgtt tttttacaac ttggaataat ttctttgtct gtgcttcgat
    36361 cccttttgca ctatcgatta ccatgaccgc actatccacg gccatcaaag tacgataagt
    36421 atcttcagaa aaatcttcat gtcctggtgt atccaagata tttactcgtt tcccttgata
    36481 atcaaactgc ataacagaac tagtaacaga aatcccacgt tgtttctcga tttccatcca
    36541 gtctgatttg gcaaaattac ctgttttttt gccttttacg gtcccggctt gacggatagc
    36601 cccaccaaac aatagtaatt gttctgtaat cgttgttttc ccagcatccg gatgggaaat
    36661 gatcgcaaaa gttctgcgat tgtccacttg ttgctttaat tttggattat tcataaccta
    36721 actccatttc ttccattcaa ttatttatat tttctctagg cacagattgt ccgatctctt
    36781 aaagaaagac aatttcatat agggctgtga caaaagccgt gtagcagtct ctttttccga
    36841 gtaaacggcg ttctagagac agcctatcag caataagccc acccaagcca aaaatacgaa
    36901 aagctgtttt tgcttggctg ctcttattac ttaatgcagg atagcttttt cacaaccttt
    36961 gtcaactact acaactgaat cagtatagca tggattcagc gaatgaaaaa gccaccaaac
    37021 cataagagtc aaatattttt ttgtcagctg actaaaagaa aagacgtgtt gcttgtttat
    37081 tcaagcaaca cgtctttcat aaccaagttt ccaattatct tcttggctcg tcatcttcga
    37141 attcttttct gaagtatctt cgttcttctt caggttccgc ttctgtttct tccggatcat
    37201 gaaaaatgac acggatttta aggattcgag aaccttccat ttcttcagaa accagcgtaa
    37261 tattatcgac atcaaacgat aacttttcgc cttcatccgg aatcatgcct aatgctgtaa
    37321 tcaaataacc agccatcgta tctacatcac tcatatgcag atcactgtca aaagcttcat
    37381 tgaactcatc aatcagcata cgtccttgga tgatatattc gtgttcatcg attttttcat
    37441 aaagattctc aacttcatct gattcatcat cgatttctcc gacgatttct tctaaaaggt
    37501 cttctagtgt tgctaaccca acgacgccgc catattcatc taataaaata gccatctgat
    37561 tctgcgtctt tttcatttca tataacagat catcaataaa gaccgtttca ggaacgaata
    37621 aaggctcctg catgattttc ttgatatcta aattatcaaa gccgaattta tgggcagctt
    37681 ttagtaaatt ctttgtatga aggattccga ctactttatc tttgtcttcg ttataaacag
    37741 ggattcttga atagttttcg gataaaactt cattcacatt ttcttccaca gtgtcgttga
    37801 tatcaatcat aaatgcatcc gttcgtggga ccatgacttc tcgggcaact ttcgtatcaa
    37861 gagaaaaaac cccttggagc atttctaatt cttcattatt caatacgcct tcgttttcaa
    37921 gcatataacg catttcatct ctggtcattt ttgaatcttc atcatcaaaa gtcatcggcg
    37981 tgatacgcgc caataaactt gtggaagcag aaagcagcca gacgaagggc ttagctacta
    38041 caccaatcaa gcgtatcagc cctgaagtga actttgcgac ttcttctgat ttatttaaag
    38101 caatacgttt agggtacaat tctccaaaaa caatcgatac ataggtcaaa atagccagca
    38161 caatgatatt tgcaatattt tttgccgctg tgccgccacc taataccgga gctaaccgtt
    38221 ccgataaagt attagctagt gaagcaccag acaaaatgtt gaccaaagtg attcctactt
    38281 ggattgtcga taggaaatta tttggattct gcaatatttt taaaagcttt tgagatttca
    38341 catctccttc atcagctttt tgctcgattc gattcttatt gatcgaaaca acagcaattt
    38401 cggaagctgc taaaaaagca ttgatcaatg tcaaaacgat caataataaa atctgcgcta
    38461 acagcgactg actctcaggg tcagcattca taatcgcatt ctctccttat aaaattaatt
    38521 tttagtttac gatagaaaaa aacgtggcac tatagccacg ttaaaatggt atcacaaagc
    38581 aattttcttt gcaataaaaa caagtgtact aaaactacct acgaggtcgt agcaattttc
    38641 ttcttgtttt cattttgctt gtcttctttg acgattttga ttatatagga aatgatcgtc
    38701 ttgcagattg cgtaaaaagg aacacctaag aagataccaa gcaatccggc aatatttcca
    38761 gctactagaa gaacgataat gatcgttaat ggatggattt tcagtgattt cccaattaca
    38821 ttaggataaa tgatattccc atccaactgt tggacgatta gcacaaccac acaacaaagt
    38881 aatgctttta ccggatcatt gaagactgtt actagaaatg caggtgctag tcctagataa
    38941 ggtcctaaat atggaattag gtttgtcaat cccgcaatga ccccaaataa gaaagcataa
    39001 tccacaccaa ttaccatata tcctaaaaat gtgaaggtac caacgaataa acattcgatt
    39061 gcttgtccgc taatgtaatt agccaatgtt ttattcagtt gccccaataa ctccacaatt
    39121 tggtttcttc ttttttctgg gaaaaactgt tggatgtttg gcactagttt ttctccgtct
    39181 ttcaacatat agaacaagat gaatggtgct gtaatgatta ctacggttgc cgaagcgatc
    39241 gttccaacga tcgaacctaa actattggat actccactaa ggaattgctg aatgattgtc
    39301 ccgtaagaaa tgtctaattg ctcaaaatat ttattgatat ctacttcctt gaacaaaggc
    39361 aattcggcta cctcttttaa ccagctttct acctgtttga tgaaatcagg catattagat
    39421 gccaatgagg aaatttgctg tactagactt gggatgacac taagtaaaat ccaaataatt
    39481 gctgcaacta aaaggagcag cacaattgcg acagcccata ttcttttgat ttttgctttc
    39541 atcaacagct tgacaatagg attcaataaa tagtaaagaa agcctgcaat cagtacaggt
    39601 gcaaataacg tggaaaaaaa tgtcccgatc ggttcgaaaa taaagtttat ttctgatgaa
    39661 atcatgatca atgcagctat gatcaataat tcaagcgacc aaaacattag tttagactgt
    39721 ctaagttttt caaacaatag atttcctcct ttctttctta ctagtatata ttatattcgt
    39781 taaaaattct tttattcttt ttttattttt gaaaacttgc catacttttt atttgtttta
    39841 ttttccagta tactatacga aaggaaggtg gctagaccat gaaagttgta caaacaaaag
    39901 atacaatgag caatatttac ttagatgctg tacggatcag gcatcaagtt tttgtagtcg
    39961 aacagggtgt gcctttgtct cgagaaatag acaaagatga agcccattgt atccacttcg
    40021 tcctgtactc agataaaaaa gaaccgcaag gaactgtacg tcttttgcct ttagaaaacg
    40081 gaaaaatgaa attacagcgg atggcgattc tttctgaata cagacaccaa gggttaggaa
    40141 aaatattgat tgaagaagca gaaaactttg ctaagaatca aggctataat acgattttat
    40201 taggggcaca gtccacagct gaaacttttt acgaaaaact aggatataca gcttacggcg
    40261 atccttttga agatgctggc atgcctcata tttatatgaa aaagacttta taaaaattta
    40321 tttcgaaaaa agcaaaaaac agcaagcttt tgagaaaaat ctctcactgg cttactgttc
    40381 ttttttgtgt ttacttacgc gacaattgct tgtaacggtt ataccaaata tcaatatagc
    40441 cttccgagaa cgggccatct ccattattga tccagtcaac cagaatcttc acattttctt
    40501 ttaggatgaa gtcaatatcg ttcgggtaat tcatcatttt gctgtgcatc tcatattcat
    40561 cgacatccaa tagtcgtttc tcgccgtcag gaaatacctt gatatccaag tcatagtcga
    40621 tatatttcaa ggcctcatcg tccagcaaaa aaggtgaagc tagattacaa taataggaaa
    40681 cccccttttc tctgatcatt gctattacat tgaaccagta ttttttatga aaataaacaa
    40741 tcgctggttc gcgcgttacc catcggcgtc catcagattc agtgactaat gtgtgatcat
    40801 tcacgccgat catagagtgt tcgcttgttt ttaataccat ggtatctcgc cacgttcgat
    40861 gcaatttgcc gtcgtgcttg taactttgga tcgtcacaaa ctctccttct tttggaactc
    40921 ccatagcaac ccttccttaa gcagcatttt gtgctttgtg tttgggtgtt cattacaccg
    40981 acatcataat tattatatca ataaaaatga gctttgccta gaaaggattc ctattgtttc
    41041 gatttttctc taactgatct accagtttca tttggacctt aggaaaaacg accgaatcaa
    41101 atgcatcagg cttcaaccac ttcgaagttt tgttctcggt aaattcttgt tctgctccct
    41161 cggttgcccg tccgtaaaaa aggagaacat gccatttcag atgactaaaa atatgagtaa
    41221 cttctcctaa atgtcgtgtc tgccaaacaa agagttcctg cttttcaaat gggagatttt
    41281 gctcttcttc tgctactagg tcatcaaaca gatcgatttc tggctttgtt tcccattctt
    41341 ttttcaatcg ctcatactcc tcttgtgtca cttccatcat tggaaatgtc cacatattcg
    41401 ccagcaattt ttggctatct ctttcttcaa aataatacgc tccagaatga ttttgaagag
    41461 ctgcactgat ataataaacg tcttttggct ttgctttttt tgtttttaca ggaaaactcg
    41521 tttggattcc tcgtttgtta gctaaacaaa aggcttggat cggacaagtc tcacactttg
    41581 gagaagttgg tgtacagata gctgaaccta gatccatcat tgcttggttg aattcacctg
    41641 gatgcttttc atcaatgatt ttccgcatcg cttcatcaaa gattttcctg ctagaagctt
    41701 ttgcgatgtc tgcttcaatg caaaacaatc tgctgactac tcgcatcacg ttgccgtcaa
    41761 ctgcaggttc tggaagtcca aatgcgatac ttgcaatcgc gcctgtcgta tatggtccta
    41821 ttcccttcaa tgagctaatt tcttcaggcg tttgcggcat ttccccatca aattctgaca
    41881 tgatctgttt agcagcagct tggatgttcc gggctcttga gtaataacca aggccctccc
    41941 atgcttttaa aagcttttct tctggagcat ttgctagctc ttcaattgta ggaaaccatt
    42001 ccatgaaacg ataaaaataa tcgatcactg tgtctactct ggtttgctga agcatgatct
    42061 cagagatcca gatacgataa ggatcacgat tatagcgcca aggcaggttt cttttttctt
    42121 gttcatacca ttgaatgaac tgatcttgaa attcttttgt ttctttatct gtccattttt
    42181 cccattcttt attcactttc ctcttccttt tccgtaatga atcgctggat catatccaaa
    42241 tcaaatcctt tttgatataa gctttgcttt acttttagat ttcttttttt aggttcaaac
    42301 cttaaatttc ttcgccatag tttatctcct tgtttgacta aataatcata ttctatttct
    42361 tgatctgctt cttgcggaag atcagctatc gcttgttgga tcacttcttg agaaaagcct
    42421 ttcgtcatca atgtttgttg gatttttctc aataattctt tttggctttt tccgtgattt
    42481 tttccaaacg ctttttcggc tgtctgatgt gcattttgaa cttggtcttc aaatgtatat
    42541 tggctgagcg cttgttcaat gatttcaggt ttcaaacctt tttgctgcat ctgctgcgct
    42601 aatttctttg gtcctttgtc acttaagcgc atattcgtgc gcacataact ttccccatag
    42661 accaaatcat cgacaaggtc caattctttt aagcgggcta cgattttatt tcgatcttct
    42721 tgaaggattt ccttttcttt taagtatgtt cggatttctt tttccgatcg caactgataa
    42781 cttaagtaat tcattgctag gtgaaaaccg aaatcagctc cgctactctt cttgatctct
    42841 tggatagttt cttcgtctaa ttcccgtcct tttaataatc gatagcgtac taatacatct
    42901 tcagatactt gtaaagcttc tccttcagat aaatctacgc gatagaaagg gcctttgcct
    42961 ttactgattc tcgtaacggt taacataaac atcctcctcg aacatatatt ctctatcata
    43021 ccacagaaaa tccccgtaat caggtattat atgttagaat aaaccacaga aaaaagaaaa
    43081 agggagatac ttatggcaga aacaattgtc aaaactggac aaacggttcc tttgaaaatc
    43141 aagcgtttag gcataaatgg tgaaggaatc ggttatttca aacggttgat catatttgtt
    43201 ccatatgcac taccaaaaga agaagtacta gtgaaaatca cgaaagcaac tcctcgctat
    43261 gcagaaggag aattaataaa agtcaaaaaa acaagcaaag atcgcgtagt ggcaccatgt
    43321 cctgtttact atgaatgcgg tggctgtcaa ttacaacact tagcttatca agctcaattg
    43381 gattttaaaa aggatctgct tttgcaagca ttggaaaaat tcaaaccagc aggctttcga
    43441 tcttatcaac ttttgccgac gatcgggatg gatgagcctt ggcattatag aaacaaagca
    43501 caatttcagt tacgaaaaaa taagcagact caaaaaattg aagctggttt atacgaagca
    43561 aactctcatc agttagtccc tataacagac tgcttggttc aagaacctcg aacacaaaaa
    43621 gtaatgaata ctgttgttca actattgaat aaatttgatg cacccatcta tgatgaacgg
    43681 acaaacagtg gaatcttccg cacaatcatg gttagaatcg gtgttaaaac tggggagtta
    43741 caagttgttt ttattactcg cagtaaaaaa ttcccgcaaa aaaacgcaat gatccgtgag
    43801 atcaatgaac gactgcccga agttgtttca atcatgcaaa atgtccaggc acaaaaaacg
    43861 tctctcgtga tgggggatga aacgatccac ttatggggaa aagaagccat tgaagaacaa
    43921 atcaatgaag tgactttcga tctttctcct cgtgccttct ttcaactcaa tcctcagcag
    43981 accgaattgc tttatggcga aggaatcaaa gcattagatg tccagcctaa tgaaacgatc
    44041 gtggatgctt attgcggagt tgggacgatc ggcttaagtg tagcaaaaca agccaaagaa
    44101 gtacggggaa tggataccgt tcctcaagca atcgctgatg caaaaaaaaa tgcggaaaga
    44161 ttaggatatc acaacactcg atatgaagtc gggacagcag agcaagttct gcctaaatgg
    44221 ttgaatgaag gttttcagcc tgatggtatc atcgtagatc caccacgtac gggtttggat
    44281 aacgcattga tccaatcatt attgaaatac cctccaaaaa aacttgttta tatctcctgt
    44341 aatgtttcta cacttgccag agatctggtt aatttaagta aaaagttcaa gattgaatat
    44401 ttacagtccg tcgacatgtt tcctcagact gcacgttgtg aagttgtcgt gaagatgacg
    44461 agactcgctg actaaatgaa agaggttgtg aaaaagtctg ccctgtatca agtaataaga
    44521 acagccaaac aaaaatagct cttcatgttt tatgaatact gtacttgtga ccgaagagtt
    44581 aacaggagga cactatttat ttaaaaaaag ggttgtgaca tagtttttgt cacagccctt
    44641 tttgattatt attggatatt cacgtctatc acttgataaa atgcatttgt cgtatcgctg
    44701 atattccata ctgctaaaat cacattatat ccttttcgat cctgcggaag tgtgatcgtt
    44761 tggttgactg tttttggtgg aacagttgct ttgtcgtcta tttttgtgat caattcaaaa
    44821 tcactaaatt tcaaaggttg attaggattc caagttggtt tggtaatgta gtaatcccaa
    44881 gtacttgtcc gatgttgtgc tgttaaattc caagtaatat ttaatgttcc tggattaacc
    44941 atgtttttat gccatctgtt agatgtctgt tcatctaaag gctcaaagcc gctgactcct
    45001 gcactagcaa tttttccatc aatgaatgta tttttggtag cttcgatact ttgcggttcc
    45061 cattgtgctc ttccgacatt ttgatttaag tttcctgctg ctgatgttcc taggtatgca
    45121 cggcttcctg gagaagtaat ataaccatgc gcaaaacctg gaatgctaaa accgaacaac
    45181 cctaaactaa ctaacccaat aaacaataac gtactaatct ttttcatgta gaaacctcct
    45241 tcatttgata accacattgt aaacgcttta ttgtattaac acaaacatta tgcttttata
    45301 attttatgtt gaagtaaaaa aggtgaaaaa agtaagatgc agattataac agaagtagac
    45361 gagaaaagta caaatagaaa acatgagaat caaatcatat gatctttttc aaaaacatca
    45421 ttcatataaa caaatgttca actttttaat aacaacaatt atcaattttt ttcttacttc
    45481 acaaactaaa tacaggtctt gctgtgagcc ttcatggtaa actaatatta tagaaaggag
    45541 ttagtaaaat gaagatgata aaagatattc gtttttgggt ttgtgttata ggaattgtca
    45601 tattaggctt tttatcaggg ttgcttagcg gaaatcccgg aaaatattac tattctttgc
    45661 aacttccacc atttgcacca cctagctgga tatttgggcc gatgtggacc ttactgtata
    45721 tattgatggg tatttctctt tatttgttac ttaatcacaa caacaaaaaa cagcgaaaca
    45781 atcttgtcgg tctttttgtg attcagttca tttttaattt tatatggtct gctctatttt
    45841 ttaatttaag aaatattttc attgcagcaa tcgatattac acttttagtt attttcttgt
    45901 cagtgcttat gtatcagttg tggctgcatc atcgcctggc aatgtggctc atgattcctt
    45961 attatttatg ggtactattc gcaactctat tgaattattc aatttatttt ttaaactaag
    46021 cgctaaaaag agacgtcctg taatttaaca catagaaaaa gtgccaccta agttagattt
    46081 tttgtctaat ttaggtggca ctctttatta accaaactat ttttttctag tacccacttg
    46141 ttgttccata ctcattattc tggtcataac cataaccatt ttgttcctgt ccagcgtaag
    46201 gatcataact ttgagtatct tgacttggtg tatagtactg acttgtatct tctgtttgct
    46261 gataataggt attcggatct tggtactgat catatgtgtt ttctgaatag gaagaataat
    46321 cggtgtaccc ttcactattc gatccatcac cgtttgtcga atcgccatct tccgaatcat
    46381 caaagaacat cattgaagca ttctcatttt tcaaattagg taatgtatcg cttgttttta
    46441 tatttaattg tttcttcagt tcattttgga tcgaaagaag atcatttttt cctaaaattt
    46501 gatagtagat atcattgatc atttgtcctt cgccttgcaa ctggtcttgt ttgattgttt
    46561 caaacgccgg ggtgtagttc gtcgctacat caagcatgtc atcccaatct aagtccgtcg
    46621 tcacattgtt ctcaactgct tttaaaattt ttctataatt gcttacgcca tctaaactta
    46681 aaactttatt gacgattttc gtcactactt cccgctgacg acgttgtcga ccgatatcgc
    46741 cttctggatc ttcgtgtcgc attcgagaat aggctaaacc tttttctcca ttcaatgttt
    46801 gttcacctac tggtacatgg acaccatcca aagtaaagtc aattttatta ttcactttga
    46861 tgccaccgac cgcattgatc aaatcttcca tgccatccaa attgatcgtt acataatgat
    46921 caataggaat atcgagcagt tgctcaattg aatccatggc catttcgaca ccaccaaatg
    46981 cgtaggcatg atttaattta tctaccgttc cataacctac gatattcgta taaatatctc
    47041 ggtccaaact gatgatcgtt gatttttttt gtttcggatt aactgttact accatcatcg
    47101 tatcagaacg tccttgttcc gttcttccta atccaccggt atctaaacct aatagcaaaa
    47161 ccgaaaaagg ttctttgtca tcaatgctta ctctctcaga acgtttggag gatattcgat
    47221 tagagttttt agaaattttg tttactgttt ggctcgcttc tcccataaat ctgattccgt
    47281 atgctgataa tccggcaatc agcaaaacga atacccctaa caaggttaat agaacttttt
    47341 gccatcgctt cataatacac ctctgtttca cattttctaa aatattgtct catataactg
    47401 ttcaatcagc aaattcactt tttaatcata agaaaacttt aaaaaacatt tttgtgtaac
    47461 gattattatt ttttaaaatt tctcaaaatt cttaactatc ataccatacc gtgaaaaaga
    47521 tcgaaagacc gaatacacgc agttcgcaat cgttttatct ttttttatgt attttttcca
    47581 gaaaaagcga acaacaaggt attttccaaa taatcgtgca gtaaaatgat cgcacatacc
    47641 tttcccatct ttttaacagt ctttgcctac cgttcagatt atcattcgat ttcacgacaa
    47701 tttcttccta tgactggtcc ttttgttaaa cccatcttct attcgtttta tttccagctc
    47761 actgcatggc tcttaaaatg actcgaacta gtgattgcat taccatcatc ttttaatgga
    47821 tagatatgct cctcttcaaa gtaaaacgat tttcttttaa agtaatagaa ttgacatggt
    47881 aatgagtatg tatactagtg gtttcacaaa tggtctttta ttcaacatcc aaaaactgaa
    47941 atttctttaa aatccattac taacgaagaa aatgttcctt gcttgataat tagttaggac
    48001 atgtcaagtg aacaaatgca tttacttagc caaaaaatct aaaaacttca taaatagaca
    48061 aaaagacacg actctctaag aagtcgtgtc tttattcaac aaattattat aatttagtca
    48121 cttcagcagc ttgaggtccg cgtgcacctt caacaatcgt gaattctact tcttgacctt
    48181 cttctaggct cttgaagccg tctccttgaa ttgctgagaa atgaacaaat acgtcatctc
    48241 cgccgtctac tgtaataaac ccaaatcctt tttcattgtt gaaccattta accgttccgt
    48301 gttccataaa tgtatatcct ccaaaaaagt tcttgcaagt aaccttgcaa gaacattata
    48361 cccaatttag aaaacgctag caagctttcg ctcttttatt ttccaaatta tttttaagac
    48421 tgatatgacg gaggaaatgg ttattttgct gcttcgaaac gtttgtttac ttcatcccaa
    48481 ttaataacat tccagaatgc tgcaatataa tctggtcgga catttttata tttcaaataa
    48541 taagcatgtt cccaaacgtc caaacctaga attggtgtct ttccttccat caatggagaa
    48601 tcttgatttg cagtagaggt aatagctaat tttccatttt ccattacaag ccaagcccat
    48661 ccagaaccaa atcgtccagc ggctgctttt ttgaattctt ctttaaaaga agaaaaatca
    48721 ccaaaagctt cattaatcgc ttcttttatt tctcctgtag gttcgccacc agcatttggt
    48781 gccatgattt cccagaaaaa tgaatggtta gcatgtccgc caccattgtt acgtacagct
    48841 gtcttgatat ctgttggaat agcgtccata tcagataata attcttctat tgttttttcg
    48901 cctaattctg ggtatttctc aattgctgaa tttaaattcg tcacataagt attgtgatgc
    48961 ttatcatgat gcagatgcat cgtttcttcg tcaatataag gttccaatgc gtcatatgca
    49021 taaggtagat ctggtaatgt gtaagtcata aaaaaattcc tcctcaatgt tttcttaata
    49081 atgtctacat tacaaagagt aacaaagaga aggaaattct tcaattgtta tgcctagtcg
    49141 tctttttcac tttgacctac ttcttcttca aaaacctcag tttctttaaa aataaacaac
    49201 ttgctgaaaa tatagttcgc aaggataaca ataatttgag tgatgatttt cgccacatac
    49261 tcattgctgt tcataacatt gatcaacaat accattgccc ccatgtccaa tccgtaagaa
    49321 aggatacggt agaagaagaa cttaccgcat tcaataagtg catgtgtaaa attcggtgat
    49381 tttgaatgga atacccaaag tttgttcgtt acaaaagcaa acaatacaga acaaaaccac
    49441 gaaatagaat tggataaggc catacttaaa tcaaaatatt ggcgtgcgag agcaaaacta
    49501 acaaaattta caatcgtagc caaaccacca aaaaagagat agactagtat ctcccaatat
    49561 ccttttgctt ctaaatatcc ttttaactgt cgatactgct tcatgagcca acctacctta
    49621 ttaaaaattc ttatttatca tactctatat ttcaataact ttcatcttta tttaaaaaaa
    49681 ttaatttttt ttgatccttt gcctttgtct ctgcttggat cgtcacatgt gtaataccat
    49741 attttaattt taataaagaa attatacgag gatatatctt ttcaatctcg cttagtagct
    49801 gatcttcaaa atcaatatgt ccgtcgaaaa taattatctt ttcgctatac tgccaaatat
    49861 ggacatgatg aacatccttt accccatcga ttgcttcaat ttcttgttcc attttttcat
    49921 agtcgatagc aggtgcactt tgtatcaaaa tagcggcagc ttttttgatc accattatcg
    49981 cttctatcaa tatatatatc gaaatgatca gtgtaataac tggatcgatc cagtagatat
    50041 cgaaaaaacg gatcaaaatt gctccgataa tcacacttac cgaagacagt gtatcactta
    50101 acaaatgcaa ataactagat tttatattca aactttcatc tgcttcttgt cgtaataata
    50161 atactgagaa caaattcgcg agcaatccaa taactgctac tgttagcatc aaatgactat
    50221 ttatcttttc tggtgaagtg aaccgcttga atgcttcaac ggttaaaaac aaggataata
    50281 tgatcaatat gaatgagttg atgaaagcac tcaatatttc taaacgctgg tagccatacg
    50341 tacgtttttt atttgcttct tttcgggcca ttttttgtgc cccgtaagaa aaaataattg
    50401 ccaatgtatc actaaggtta tggaaagcat ctgaaacaag agacaaactc cctgacataa
    50461 tccctccaat aaattctgat aaagtgatca ccgcattcaa aaccactact ccaaatagtt
    50521 tttttgatga tctctgtggc tgtgtaggca ctattccttc ctccatttta tttatattgg
    50581 atagtcttta gacaagaata acattttttt gatatttcac caatcattca gctgtttcct
    50641 taaagcactt gtatttcact tgatacttcg ctagaattgc aagtgatgac agtactagat
    50701 gaggagtact tatgacaaca aaacaattaa ttatcagttc ctttatacga ttcaaagacc
    50761 taaaggaggc gagaaatgtc ccattttgga aagccattgt ctatctttta gttttgagta
    50821 taattatggc tttgccaatc tcttttcaag tttttcaagt cttaaacaac attcaattgg
    50881 atgggcaaaa gattgctact cgcattcctg attttacaat ccaaaacggg cagcttcaaa
    50941 ccgaagaaaa agaaggattc atttaccaaa caaactccat tatcttcaca tttgatccag
    51001 agggaaaacg aacagaacag gacatctcta ctgatttgat ggggaatttt gttagtgtcg
    51061 ggatgttaaa aaacaaactt atcatagctc ttcctaatac aggcacgact tctgctttgt
    51121 tgaacaataa ccaattagaa cttccctaca ccaatgaatc tttaaaaaac ttaacaggta
    51181 agcagctccg ttctttttta agtgaagcat ctataccact ttggataaaa gtcctgacat
    51241 ttatattttc tatttatcct agttttctga atctgctgat cactttgcta tttaccaaca
    51301 ttgctgcttt tctctatgca cgctttcgac taacaaaagc tacttttctt gattgtttaa
    51361 aaacattgat ctattcaatt tcattgccta ctataattgc aacaatcttg atggtctttc
    51421 ttccttcttt tgacactagc gccttcattg cttttgcagg aatctttatt tttgctcaag
    51481 ctgtcaaagg atgggcaaaa atatcgatca attaagaaat aaagacaact cgttatttct
    51541 acttcaatag acccttttag aggttgtgac atttttttgt cacagcccct tttttatttg
    51601 aaaaatattt ctttctcaaa aaacaagcaa ggcgcttcaa agttcttctt gtatgcgcta
    51661 cacttagagt aaagaaaggc gggaaattaa ctatgtcaga aagaatcatt tatgcagatc
    51721 gtccatttcg tgatgaattt atcgaagaaa tccatactat agcgcctggt tatatcttta
    51781 aaacagaatt acaaccagag gatctacaaa atgtagagat cagtttgggc tggaactcag
    51841 actaccaaga aaaactatta gcctcttcta ccttgaaatg ggtccaatct atctcagctg
    51901 gtgttgatca gctacccctt gagacttttt caaagaaaca tattttactt tcaaatggta
    51961 gtggcatcca cagtgaatcg attacggagc atgtcttagg aatcatcctt gggtattctc
    52021 gtggtctttt tcaagcacaa aaggcacaga gtgacatgaa atggttaggt tcatcggtcc
    52081 attaccaatc tatccaaggg aaaaaaatac taatcattgg aactggccat attggaaaaa
    52141 tgattgcaaa aaaatgcaaa gcattagaca tgaactgcta tggaatcaat acatccggtc
    52201 atccagcaga aggaatggaa aagacttttt ctttaaatca actaaaggaa gttcttcctg
    52261 aagtagattt cgtagtcaat atcttacctc taacggagga aacaactggg ctctttgatc
    52321 agcatatgtt tgaacacttt gatccaaaat ctgtattcat caatgttggc cgtggtgctt
    52381 ctgttaagac acaagatctg gtgcaggctt taaataacca gcaactttcc tttgcagcat
    52441 tagacgtttt tgaggaagag cctcttccac aagatcatcc tctttggaaa atggacaatg
    52501 tactgattac ttcccacatt gcaggtttga cacctgattt tcaaaagaaa ttaatggcta
    52561 tttttttaac caatctgaaa agctactttg ccacccatga gcttcaaacc aatcaagtaa
    52621 aattgtctgc aggatattaa tagctgaaaa caatattttc aaaagaaaaa agagaaggtg
    52681 acaaaaattg tgtcaccctc tcttttttta ttgtttttta aagtgatagg ttggctcctc
    52741 caggttggga ttataatcaa caagtaaatc atatccttta aagaaccatt catctgcttc
    52801 ctcgataaaa aaaagtgtcc catcaatttc cactttcttt acaggatgtt ctggctgttc
    52861 aactgacatt ccaatcgaaa aaccatcatg aacctctgtt ttgccgtaga cttttccaaa
    52921 aaaacgtatt ccgtaagttt ctggcagatc aatttctgag tcaaaccact tttgtgcttt
    52981 tggcgttacc gttaatttca tcccaacaac ctactttctc ttttctttct attgattcat
    53041 cttatcgtct agaatatcca catcgcctgt ctctccaata accagtagat tatcattttc
    53101 acgaacatat tcatctgctg caggagaagc gataaccgtt tgatctactc ttcgtatggc
    53161 gactactgtt aagtcaaaac gttgcctgaa atttaattca gctaatgttt tgttgaaaaa
    53221 tttaggattg gagactcgga tttctgctaa agaatattta tctgacaact ctaggtaatc
    53281 taaaatattc tttgacacta aattatgcgc aatccttatt cccatgtctc gctcgggatg
    53341 gacgacgcga tcagctccga tcttttcaag tactctggca tgatactcat tttgggcttt
    53401 tgctaaaata tttggtacgc ccatttcctt taccatcaga gtaactaaga tactggcttg
    53461 aatatcttct ccaatagcga caattacatg atcgaaattt cttatgccta atgatcgaag
    53521 tgtcatttca tcctgtgcat ttgccacaac agcatgagtg gctatattca tatattcatt
    53581 gacccgatct tcattactat caatagccag tacttcttga ccagcttcga tcagtgttcg
    53641 gcagatactt ccgccaaatc gtccaagacc tacaattgca aaattttgtt tcaccgtttt
    53701 cctcctttag tatcttcttt tctcagtata acaaagcctt tacaaaaaca aaagcaagca
    53761 tcattattgt aaaaaagcca agaaaaataa tagttatttt ctcagctttt gattatcctc
    53821 tttatcatcg tttttatttc accaaaccat gtttgaatgc atagatagcg gcttgtgtac
    53881 ggtcttccac ttctagctta gccaatatat tggaaacatg tgtttttact gttttcagtg
    53941 taataaacaa ttcgtccgct atttcctgat tactttttcc ttcagaaatc agcattaaaa
    54001 tttcattttc ccgattcgtt agttcttcat gtaatacagg ctcatttcgc cgactcattt
    54061 tttccatcat ttttgttgtc acttctggtt ctaatactcg ctcgccacgt tgcgttgccc
    54121 ttatagcatc agcaatttca tgtgcggtag aggtcttcaa caaataccct gctgcacctg
    54181 cttcaatggc aggataaact ttttcgtcat caataaaact ggttacgata atgattttag
    54241 cttctggcca atcttttaag attgcttttg ttgattcgat accatccatt tcttccatga
    54301 ctaagtccat taaaatgacg tccggtcgaa gtgtcatcgc cttctcatag ccttgtcgtc
    54361 cattttcagc ttctccaatt acttcaatgt cttcttgaat agataaataa aaagagacgc
    54421 ctaagcgcac catttcatgg tcatctacta ataaaacttt tatcatcctt atctatgcct
    54481 ccttcatcaa agggaccttg atttctacac ttgtaccttg acctttaaaa ctaatgattt
    54541 ttactgttcc accaatacca gctactcgtt ctttgatatt gttcaatcca taacttcccg
    54601 ttttcgtttc attcatatta aaccctgttc cgtcgtcaat aatacgtaac aaaagattat
    54661 tgtctatttt gtgcaaatat acctctaatt cattggcttt agcatgtctt aatgtatttg
    54721 ataacaattc ttgaacgatt cggaacaagt gatcctcaat ggaactagat agttttacat
    54781 cttctacatc ccatttcagc gaaatctgga ttttattttg caattccttc aataactgct
    54841 cgataccttg ctttaaactt ttctcttcta aattgactgg acgtagatga agaagcagcg
    54901 cacgcatctc agactgggaa gcgttgatga tctctgctac cattttcaac tgcttgcgaa
    54961 acatttctgg tgtctcgctt ttttctgctt gctccgtcaa tgccgacatc atcatcattg
    55021 ctgcaaacaa ttgttgcgaa actgaatcat gcagctcacg ggctaatcga tgtctttcta
    55081 attctaaaat ttcttctttg gtttgtccat ctacatattg gggacggctc gttacaattt
    55141 gtaattcact agatacttca atcatttttt cttttatctt agtgatttcc ttatcaatat
    55201 ctttgatgta taaatcgtcc gatgcacttg ggatcggaag aagcaacaat ttggattcat
    55261 aattgccaga agaaagtgca cgcagctttt cttcgatttt cccgtatttt gtcttttgaa
    55321 taagtgataa taatagaaag acaattaatc ctacacctaa ggaaatggct aacaaatgga
    55381 agataagcgg aacatataat aaacgtgcac gcagtaattc tccccaccaa tgactttgat
    55441 tgctggcata aaaataagtg aaaagtgaaa atagaataat aaggaaagcc gcaatccccg
    55501 aataaacagc tagcatcgct ctggatattt ttcccatcat attcgtatca cctcgacatc
    55561 tccaatcaag gtattagtaa taatcttcaa tctacgaggg ttttcatcat aatcactgct
    55621 gtagattttg atttgttcat ttttcaaaga aaattgctct tcttcaaaca agacatttcc
    55681 tactaatgtc gcatgctcta atcggatggc tacgcccaaa ggtactaaga tccgtgttct
    55741 gcctatccct tttcttacaa tcacaatatt atcatctttt ggcaaaagcg tattgcccaa
    55801 atctatgata gtatcaccag aaatgacggc gatgttgata tcgtcccatt catagacgtc
    55861 gtttccaata cgttggttac cgaataattg ctgtcttttc cgctcattat tatgtgtttt
    55921 taattgctct gtttggatca tcatgatctg tttctttcgc caaaaagcat ttttggttaa
    55981 atctatccct gaaatctcta cacctttcag accaataaat aaaacggcaa atacagccat
    56041 catccataaa gcaggactgt tgactaagct aaaaaaaatg accaaacttc ctaatatcaa
    56101 ttgaaaattt tgaaatttag tacgaggatg tttgcgcata gctagatata tattgaaaat
    56161 accgaatatc actaaaagca aaagtccagt attgtttacg atttgccaaa cagcaaataa
    56221 cagcagtagt gcttcaacta ccacaaaaaa acgccaagaa ctattcatcg ctctttctcc
    56281 ctcctgacac attctcattt catcatacct atttttttaa ctgttggcta taggacttta
    56341 gatgtaagat cgtttgttga aatctaaaat acacaaagag aaaaagatct agagtgtatc
    56401 atcagtaaga tgaactctct agatctttca gtcagactac gcttgttcta ctttgacgat
    56461 tttaactaac atatcgccac ctggagtagc aatagttact tcatcatttt tacgtttgcc
    56521 aatcaatgct tgcgcaatag gagaatcatt ggaaattttg ccagaaaacg gatctgcttc
    56581 agcgcttccg acaatcgtgt actcttcttc ttctccatct ggtagttcga tgaatgtaac
    56641 tgttttacca attgatacct catctgcatc tacaccgtcg ttatcgatga tttgagcaaa
    56701 acgaatcata ttttcaattg ttgtgattct tccttcaaca aatgcttgtt catctttcgc
    56761 tgattcatat tcagagtttt cggaaagatc tccgaaaccg cgggcaattt tgattcgttc
    56821 aatgatttct ccgcgtttga ctgtttttag ttcttctaat tctttttcta atttttcttt
    56881 accttctaga gtcattggat aaactttctc taccatgtgt aacgtctcct tttttcgata
    56941 aaataccgca aaaggtaatc ttttgaggaa tatagtccaa aaaagattac cacgcttttc
    57001 ttcaaatgta aatgtttttc taaaaatgat caatgtctag agcctgtttt tctaagaatt
    57061 atttacatat ttttccacta attccatatg ttcttcataa gttttagcga aataaacatt
    57121 tccagtgctc gtatctgcta cgaaataata atagtcattt tctgctggtt ctaatactgc
    57181 cttgattgcc tcttcgcttg gattgtcaaa aggtccaggt ccatagccgg tattggtata
    57241 caaattatat ggtgaatcta cagctgtatc ttcatacgtc actaattctt tgtgttcacc
    57301 taatgcgtat aaaacagaga tatctgactg aagtggcata tttgctttga ttcggttaaa
    57361 gaagacttgt gcaatgtttt tacgatcatt ttcttttacg ccttcttttt caactagaga
    57421 agctagagtt aaaacttctt gtacagtcaa atttttctgc ttgatagctg aataatagtt
    57481 ttgcatgacc gtattcgtct tgttcaccat ttcaatcact agatccttaa gcgaagtact
    57541 cgtgtaataa tcatatgtgg ctgggaataa gtaaccttcc aaacggtatt ttgtgttctc
    57601 agctttagat gcactttcca acagttctgg gaatttttgg tgcaactcgt taaagaaagt
    57661 ctcatcattc actaaatcta aaaattcttt cttgtcttta ccagttacct tcgctacccg
    57721 ttcagcaatc tgatcgatat cgtacccttc tggaatggca attttcccat ctgcaacttt
    57781 tgttggctca gaagtaccgc cttcttgcaa ctgtttgcca atctcgtcaa gagtcatatt
    57841 aggcgctaac tgataatagc cagcttgaaa gccagttaaa tttttaaatt ttgtataata
    57901 attgaaaaca atcccgcttt taataatatt gtccttctcc aaaatctcac caatctgctt
    57961 gttagaagag ccactcggga tctcgacttg gactaattgg tcatctgatt tatctaaagg
    58021 cttcaacccg ctatctacat aacgatacac ggtaaatcca agaaatccgc caataatcaa
    58081 taatgtaaga gcaatcacta aaatgatctt cctcacaatc ttatcttctt ttttacgcag
    58141 atttctccgc ttgtcgatta tatctgctgt agctgcctta ctggcttctt ttttatcttt
    58201 acttgggtgt tgtttgtttc ctgacaaaac aactcctcct tactatcaag ttcgtaactt
    58261 tattcattat acatgatatt tgaattggcg tgaatgattt tatttaaata ttctatcaaa
    58321 aatgtaagta gtaaatccat tactataaga ttaaaataaa tgttatcaag atacaagcta
    58381 ttttagcttt attctttctg taaaaaagaa aggagactaa ataaactatt atgaaaaaag
    58441 gaaaacatgc taaaaaaaga aaatattcat ttttaatgat cgttgtcgtg ttgtttagcc
    58501 ttagtgcgtt ctctacagga actattcttg gatggcaatt ttacaataat gaacactctc
    58561 agatagttgc ccatgctcaa tcagctcaaa aaaagttgat actgactacc aatgaacaac
    58621 agctcgttga aaaaatcgat caactattaa gaaaaaatga ttatattggc tcaatttacg
    58681 taaagaaaaa taatcgcatc atcatggaaa aaggctatgg ctatgcgaat aaactcacgc
    58741 aacaaccaaa tgatccttct ctttattatc agattggttc ggttcaaaaa gcattgacta
    58801 ctcttttgat tttaaaacaa gtcgagcgtg ggcacctttc tttagatact aagctggctc
    58861 aattctatcc acaaattgct ggcagccagc aaattactat ccgtgacttg ctgtatatgc
    58921 gctcaggctt gcaccgaact gcttctccaa ccataccgat gactgatgaa gaagtcgttc
    58981 aatttgcgat tcagcactta aaatttacag attatcagac ctctcattat gattcattga
    59041 actttaccat attgactgga attttgatca aattaacaaa tcaaccgtat gaaaaattat
    59101 tgaccgatga tatcatcgaa cctttaggat tacagcatac aaaattttat gaccaagtca
    59161 aaaattcatc caatcatgca ctatcctatc aaatgtctaa agaggatgat tactttaaac
    59221 cactgacaga atctgaaaca gagatccata acgaattagg gactggtaat atcagtatgt
    59281 ccgtctatga tttaaatacg ctgtttacac aagttttatc tggaaaacta gtttccaaag
    59341 acttactctt ctcattatgg cgtgaaaatg cgaatggaca tccatatagt ggtggggtat
    59401 atagcggaga taattatatc ctgtcgcaag gaaatatcga ctcttttgat acatctgcta
    59461 tatttagcaa agattcacag gatgctatca tcatggaaag caatataaaa gctgacaaaa
    59521 ctatcaaact gcctactgct gatctaagaa accaaatcta tgacctgatg gaaggaacta
    59581 ctaagttggc aaatagctga tatgatgaaa agatagcaaa tactacttct ttgaatagca
    59641 tttgcttaaa aaaagtactc gactaaacgt aggaaagagt gtgggacaaa tctaaaaatc
    59701 aatttttgct acagacttta attccaaata aacagaacag aaagaggtgt tcttctttct
    59761 gttctgtcca aattattcta agatttctct ttaccaacat tatttgacaa agggcctatt
    59821 aaatctaaaa tagtatcttt agattgctaa aatatgtgct agcaaatcat tcatggcttg
    59881 ttcttatttt taattttatg caataaaaaa gaagaacaat tagcgtgatt atagaaataa
    59941 ataatgagat tttagaaaaa aatgtgtatg aatacctgat tgttacttta tttattccac
    60001 tttcactttt tactgtaaca aaaggacctc cttgttttag tactgtagca ttttttgaat
    60061 taacagtaac cgttaatcct ttataccgga atacaggtaa aactattgtt ttgccttttg
    60121 aagatttaaa cgtaaatgta atttcatctt tatttggaga aaagctacta taaataactt
    60181 gaccatcttc tgtaacttga tggtttttca aaagcaattg atctttttta tagcctatag
    60241 gtacataatc aaaattctca aattcttcaa gtttattttc catttgttca ttagaataag
    60301 ttccttgaaa attcatttct ttcaccatgt taactactga tgaataattt aaaattgaaa
    60361 tagctaatat taataatagt ataaaatttc ttctccttgt ataagaaaat ttttccaact
    60421 gtggagaaat aaatagagat actgaaaaag atatgaacaa tgttgaaaat atcataaaac
    60481 gccaaggagc ttgaataata tttaaaggag tattttgtaa ggcaaaccat ggaaatattt
    60541 ttgtacaaag tagaatagat attataccca ttatataagt gattttagat aagattccta
    60601 attttttaaa gttaaatgtt agtataatta aacaaataag caaagttaag ccaataccaa
    60661 atgatagtaa ttctgaatct atacttccaa tcaaaaactc tttacccaga taaattgctc
    60721 ttttttgtaa tatatccaca taaggtctat tcagatcttg atacaatgtc tgctcaatca
    60781 taggacctat aaacgctagt gaaagaagta aagtaactat agcagctttt attaatttaa
    60841 taattaagaa gatttctatt ttctttttcc gataaaattg aataattaaa gcaattataa
    60901 tcattaccat agtcatagct acagaaagaa catgagtgta aattaataaa gtcatgctaa
    60961 tcgccaacat aacccaagat tctttttttg agtcgtaaag ctttataaac ccgagtaaaa
    61021 taagaggaag tattgacatt gcgagtaatt cccccattgc ccctcgaaga aatatttcta
    61081 cactcctaaa agaagatgtt gtatatataa tagcgaaaaa ggagctagta acatgttttt
    61141 tggtaatttc atacattaca taatgacata taaatagagt aatgagcgta acaatataaa
    61201 gaaaaaggtt atagcctatt gctaaattag taaacttgat caataaaaat aaaggatata
    61261 gagttaacca tgggtaaaaa ttatttactt gcatgccata tgatctaaac gtttcaaaat
    61321 taatagggga gctaaaaata gattctaaac ttaacgcacg attaatgtga aatgccgtat
    61381 cataaaagcc aaatatttc
//
LOCUS       DAFLVO010000009        56980 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.009, whole genome shotgun sequence.
ACCESSION   DAFLVO010000009 DAFLVO010000000
VERSION     DAFLVO010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56980
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.009"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(259..762)
                     /locus_tag="L1U99_000582"
     CDS             complement(259..762)
                     /locus_tag="L1U99_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBN1211152.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            1121..2146
                     /locus_tag="L1U99_000583"
     CDS             1121..2146
                     /locus_tag="L1U99_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBN1211153.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            2469..3347
                     /locus_tag="L1U99_000584"
                     /pseudo
     CDS             2469..3347
                     /locus_tag="L1U99_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
     gene            3823..3939
                     /locus_tag="L1U99_000585"
     CDS             3823..3939
                     /locus_tag="L1U99_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBN1211154.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            4867..5205
                     /locus_tag="L1U99_000586"
     CDS             4867..5205
                     /locus_tag="L1U99_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211155.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            5299..5529
                     /locus_tag="L1U99_000587"
     CDS             5299..5529
                     /locus_tag="L1U99_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211156.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            5929..6300
                     /locus_tag="L1U99_000588"
     CDS             5929..6300
                     /locus_tag="L1U99_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBN1211157.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(6574..7266)
                     /locus_tag="L1U99_000589"
     CDS             complement(6574..7266)
                     /locus_tag="L1U99_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBN1211158.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(7269..8054)
                     /locus_tag="L1U99_000590"
     CDS             complement(7269..8054)
                     /locus_tag="L1U99_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBN1211159.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            8291..9691
                     /gene="lacG"
                     /locus_tag="L1U99_000591"
     CDS             8291..9691
                     /gene="lacG"
                     /locus_tag="L1U99_000591"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBN1211160.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            9716..10033
                     /locus_tag="L1U99_000592"
     CDS             9716..10033
                     /locus_tag="L1U99_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBN1211161.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            10046..11719
                     /locus_tag="L1U99_000593"
     CDS             10046..11719
                     /locus_tag="L1U99_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HBN1211162.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSGMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            11733..13364
                     /locus_tag="L1U99_000594"
     CDS             11733..13364
                     /locus_tag="L1U99_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HBN1211163.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(13855..15420)
                     /gene="guaA"
                     /locus_tag="L1U99_000595"
     CDS             complement(13855..15420)
                     /gene="guaA"
                     /locus_tag="L1U99_000595"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBN1211164.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(15479..16402)
                     /locus_tag="L1U99_000596"
     CDS             complement(15479..16402)
                     /locus_tag="L1U99_000596"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBN1211165.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            16598..17203
                     /locus_tag="L1U99_000597"
     CDS             16598..17203
                     /locus_tag="L1U99_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1211166.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            17511..18527
                     /locus_tag="L1U99_000598"
     CDS             17511..18527
                     /locus_tag="L1U99_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBN1211167.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            18668..19969
                     /locus_tag="L1U99_000599"
     CDS             18668..19969
                     /locus_tag="L1U99_000599"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBN1211168.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            20015..20677
                     /gene="deoC"
                     /locus_tag="L1U99_000600"
     CDS             20015..20677
                     /gene="deoC"
                     /locus_tag="L1U99_000600"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBN1211169.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            20698..21096
                     /locus_tag="L1U99_000601"
     CDS             20698..21096
                     /locus_tag="L1U99_000601"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBN1211170.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            21162..22244
                     /locus_tag="L1U99_000602"
     CDS             21162..22244
                     /locus_tag="L1U99_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1211171.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            22456..24018
                     /locus_tag="L1U99_000603"
     CDS             22456..24018
                     /locus_tag="L1U99_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1211172.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            24011..25144
                     /locus_tag="L1U99_000604"
     CDS             24011..25144
                     /locus_tag="L1U99_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1211173.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            25144..26100
                     /locus_tag="L1U99_000605"
     CDS             25144..26100
                     /locus_tag="L1U99_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1211174.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            26199..27365
                     /gene="deoB"
                     /locus_tag="L1U99_000606"
     CDS             26199..27365
                     /gene="deoB"
                     /locus_tag="L1U99_000606"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBN1211175.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            27389..28207
                     /locus_tag="L1U99_000607"
     CDS             27389..28207
                     /locus_tag="L1U99_000607"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBN1211176.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            28224..28931
                     /gene="deoD"
                     /locus_tag="L1U99_000608"
     CDS             28224..28931
                     /gene="deoD"
                     /locus_tag="L1U99_000608"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBN1211177.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(29229..29915)
                     /gene="gpmA"
                     /locus_tag="L1U99_000609"
     CDS             complement(29229..29915)
                     /gene="gpmA"
                     /locus_tag="L1U99_000609"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBN1211178.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(30087..30668)
                     /locus_tag="L1U99_000610"
     CDS             complement(30087..30668)
                     /locus_tag="L1U99_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1211179.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(30801..31484)
                     /gene="rpiA"
                     /locus_tag="L1U99_000611"
     CDS             complement(30801..31484)
                     /gene="rpiA"
                     /locus_tag="L1U99_000611"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HBN1211180.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            31803..32216
                     /gene="rpsL"
                     /locus_tag="L1U99_000612"
     CDS             31803..32216
                     /gene="rpsL"
                     /locus_tag="L1U99_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBN1211181.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            32300..32770
                     /gene="rpsG"
                     /locus_tag="L1U99_000613"
     CDS             32300..32770
                     /gene="rpsG"
                     /locus_tag="L1U99_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBN1211182.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            32864..34951
                     /gene="fusA"
                     /locus_tag="L1U99_000614"
     CDS             32864..34951
                     /gene="fusA"
                     /locus_tag="L1U99_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBN1211183.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            35123..36310
                     /gene="tuf"
                     /locus_tag="L1U99_000615"
     CDS             35123..36310
                     /gene="tuf"
                     /locus_tag="L1U99_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBN1211184.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            36717..37025
                     /gene="rpsJ"
                     /locus_tag="L1U99_000616"
     CDS             36717..37025
                     /gene="rpsJ"
                     /locus_tag="L1U99_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBN1211185.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            37056..37685
                     /gene="rplC"
                     /locus_tag="L1U99_000617"
     CDS             37056..37685
                     /gene="rplC"
                     /locus_tag="L1U99_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBN1211186.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            37713..38336
                     /gene="rplD"
                     /locus_tag="L1U99_000618"
     CDS             37713..38336
                     /gene="rplD"
                     /locus_tag="L1U99_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBN1211187.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            38336..38626
                     /gene="rplW"
                     /locus_tag="L1U99_000619"
     CDS             38336..38626
                     /gene="rplW"
                     /locus_tag="L1U99_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBN1211188.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            38665..39498
                     /gene="rplB"
                     /locus_tag="L1U99_000620"
     CDS             38665..39498
                     /gene="rplB"
                     /locus_tag="L1U99_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBN1211189.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            39541..39819
                     /gene="rpsS"
                     /locus_tag="L1U99_000621"
     CDS             39541..39819
                     /gene="rpsS"
                     /locus_tag="L1U99_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBN1211190.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            39842..40189
                     /gene="rplV"
                     /locus_tag="L1U99_000622"
     CDS             39842..40189
                     /gene="rplV"
                     /locus_tag="L1U99_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBN1211191.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            40203..40859
                     /gene="rpsC"
                     /locus_tag="L1U99_000623"
     CDS             40203..40859
                     /gene="rpsC"
                     /locus_tag="L1U99_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBN1211192.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            40862..41296
                     /gene="rplP"
                     /locus_tag="L1U99_000624"
     CDS             40862..41296
                     /gene="rplP"
                     /locus_tag="L1U99_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBN1211193.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            41286..41474
                     /gene="rpmC"
                     /locus_tag="L1U99_000625"
     CDS             41286..41474
                     /gene="rpmC"
                     /locus_tag="L1U99_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBN1211194.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            41499..41765
                     /gene="rpsQ"
                     /locus_tag="L1U99_000626"
     CDS             41499..41765
                     /gene="rpsQ"
                     /locus_tag="L1U99_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBN1211195.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            41823..42191
                     /gene="rplN"
                     /locus_tag="L1U99_000627"
     CDS             41823..42191
                     /gene="rplN"
                     /locus_tag="L1U99_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBN1211196.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            42228..42536
                     /gene="rplX"
                     /locus_tag="L1U99_000628"
     CDS             42228..42536
                     /gene="rplX"
                     /locus_tag="L1U99_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBN1211197.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            42564..43103
                     /gene="rplE"
                     /locus_tag="L1U99_000629"
     CDS             42564..43103
                     /gene="rplE"
                     /locus_tag="L1U99_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBN1211198.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            43122..43307
                     /locus_tag="L1U99_000630"
     CDS             43122..43307
                     /locus_tag="L1U99_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBN1211199.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            43343..43741
                     /gene="rpsH"
                     /locus_tag="L1U99_000631"
     CDS             43343..43741
                     /gene="rpsH"
                     /locus_tag="L1U99_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBN1211200.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            43773..44309
                     /gene="rplF"
                     /locus_tag="L1U99_000632"
     CDS             43773..44309
                     /gene="rplF"
                     /locus_tag="L1U99_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBN1211201.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            44470..44826
                     /gene="rplR"
                     /locus_tag="L1U99_000633"
     CDS             44470..44826
                     /gene="rplR"
                     /locus_tag="L1U99_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBN1211202.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            44847..45347
                     /gene="rpsE"
                     /locus_tag="L1U99_000634"
     CDS             44847..45347
                     /gene="rpsE"
                     /locus_tag="L1U99_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBN1211203.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            45362..45541
                     /gene="rpmD"
                     /locus_tag="L1U99_000635"
     CDS             45362..45541
                     /gene="rpmD"
                     /locus_tag="L1U99_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBN1211204.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            45585..46025
                     /gene="rplO"
                     /locus_tag="L1U99_000636"
     CDS             45585..46025
                     /gene="rplO"
                     /locus_tag="L1U99_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBN1211205.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            46025..47320
                     /gene="secY"
                     /locus_tag="L1U99_000637"
     CDS             46025..47320
                     /gene="secY"
                     /locus_tag="L1U99_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBN1211206.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            47382..48029
                     /locus_tag="L1U99_000638"
     CDS             47382..48029
                     /locus_tag="L1U99_000638"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBN1211207.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            48220..48438
                     /gene="infA"
                     /locus_tag="L1U99_000639"
     CDS             48220..48438
                     /gene="infA"
                     /locus_tag="L1U99_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBN1211208.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            48471..48587
                     /gene="rpmJ"
                     /locus_tag="L1U99_000640"
     CDS             48471..48587
                     /gene="rpmJ"
                     /locus_tag="L1U99_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBN1211209.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            48605..48970
                     /gene="rpsM"
                     /locus_tag="L1U99_000641"
     CDS             48605..48970
                     /gene="rpsM"
                     /locus_tag="L1U99_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBN1211210.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            48998..49387
                     /gene="rpsK"
                     /locus_tag="L1U99_000642"
     CDS             48998..49387
                     /gene="rpsK"
                     /locus_tag="L1U99_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBN1211211.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            49467..50405
                     /locus_tag="L1U99_000643"
     CDS             49467..50405
                     /locus_tag="L1U99_000643"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBN1211212.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            50433..50813
                     /gene="rplQ"
                     /locus_tag="L1U99_000644"
     CDS             50433..50813
                     /gene="rplQ"
                     /locus_tag="L1U99_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBN1211213.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            51085..51924
                     /locus_tag="L1U99_000645"
     CDS             51085..51924
                     /locus_tag="L1U99_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBN1211214.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            51900..52769
                     /locus_tag="L1U99_000646"
     CDS             51900..52769
                     /locus_tag="L1U99_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBN1211215.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            52759..53556
                     /locus_tag="L1U99_000647"
     CDS             52759..53556
                     /locus_tag="L1U99_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBN1211216.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            53759..54505
                     /gene="truA"
                     /locus_tag="L1U99_000648"
     CDS             53759..54505
                     /gene="truA"
                     /locus_tag="L1U99_000648"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBN1211217.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            55170..55407
                     /locus_tag="L1U99_000649"
                     /pseudo
     CDS             55170..55407
                     /locus_tag="L1U99_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(55551..56327)
                     /locus_tag="L1U99_000650"
     CDS             complement(55551..56327)
                     /locus_tag="L1U99_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBN1211218.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            56450..56857
                     /locus_tag="L1U99_000651"
     CDS             56450..56857
                     /locus_tag="L1U99_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBN1211219.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSIHAFLIIITQNLNHKPYLSFIKNHEKFLIRNYKISGGGC
                     YLLECRFTSKKSMNSFLEQLNEYANYKLSIVID"
BASE COUNT        18215 a        10164 c        12152 g        16449 t
ORIGIN      
        1 attaagacgg aattcctttc tagattgaga tattgactag gaagaatgtt aagattttaa
       61 gcctttaagc taaaaaaaaa ccctttttgt taaataaggg gaatatagcc tgtcagtttc
      121 aaactgcaag tcgtcctgct gcaataatat agtagattag agatgaaaat agattttttt
      181 aaaccaatga ctgaataaaa agaccgtcat agatacacat tggaatgtgt ctattacggt
      241 ctttttttac gaacgatttt attgaagacg gacagttcgg gtcaaaaata aaaaagctac
      301 gatcagaaat aagaataaaa tgtatcccaa aataatggct agacggtcta acttatttgt
      361 cgatagatgt ttgtttagaa gttgataggc ccataaacct atcagtcctc ctgttgtatt
      421 agttatcaaa tcagtgatgt ccgctacgcc aataccgaat aggaattgaa tcaattctgc
      481 caagaagctt acaaggaaaa taatccctaa ttttttagaa aaagaaagtc tcttgaaatt
      541 gacattcaaa agcaccccaa aaggaaaaaa gacaatcaag ttataagtgg tctcacgtaa
      601 taccgtcgta ttttcaaaag aaaaagtaga aaaagggacg agattgacat tgctgtaaga
      661 ataagtgaga aattgtggaa gattaaatga tagcttgaat aaaatcaacc ataatagaaa
      721 gaataaataa atccctaata aaaattttga tacataccgc atagacatct cctccattta
      781 aaaagtatac catcgaaaac cgctgaaaaa tcataaaaaa gtatgaagtt taaggaccaa
      841 cgtagttatc gtacgaaaat tagaagcttt tttttgttgg gaatccggtt tctttaacaa
      901 agctaagata gcgagttgct tggaaaagtt gctatctttt ttctgtcaaa acgactcgga
      961 atgttcgttt tttgttctaa tttctccaag ttgtttactt tttgatacta agtttatgaa
     1021 aaatcaagaa atagttgtta tactaggtaa tgctgacaaa cgggattggc atttcatctt
     1081 ggttcagctt tttttccaat tactaggaag gagggataga ttgttcaaga cttattttcg
     1141 tttcaataaa atacaagata atccttttcg tatcatgaat ctgatgctac ttatctttat
     1201 tgtattatgg ttaggttaca taaatcatga ttttttgatt tcaagttttt catcattagg
     1261 gatctttact tttttctatt atcaaaacat accgatgaaa tatttgctga aacgtatgtt
     1321 tctgatcggt tgcggactgt tggttgcttt cgttttgggg atcttatcga cttatgtttt
     1381 atggcttgaa ccatttgccg tagctttggt tgctttttcc agcagattcg tgttgcgatt
     1441 attccatatt tctaaaccag gtggcttgtt ttttgcgatg ctttctgcca tgggaacgag
     1501 catgcagctg ccaatcgctc aattaccgat cgtctcactt tattttttta tgggtgtcgt
     1561 ttttgccctg attgcggcag tgattacaaa attactggat tcacggcctg agcagacaat
     1621 tgaaaaagca actttaaaag aaagatttca cgaagagcct ttagtgatca ttgattctgt
     1681 tttctacagc gctgccttat ttctttccgt ttatgtcagt cacggcttga atctgcataa
     1741 tccttattgg ttgaccttgt catgtgcatc gattttgcta gcagaaaact tggatgcgat
     1801 gaagcatcga caagtccaat atctgattgg atcgatgggt gggttatgtg tgtcggcatt
     1861 cttgtcattt gtgccgttta cgcagttgca gaccattttt ctgatcactt ttctatatgg
     1921 aatcgcacaa tttctagttg ctagaaatta tgcagttgct aatatttttc ttaatccgat
     1981 ggcgttgatg ctatctacac ttattcgtgg agcatacttg atttctttga tcgaatatcg
     2041 ttttttaggg atcgtcatag gaagtttcat cggtttaggt gttgcgtggg taatgacggt
     2101 tggtttgcaa cattatttaa cggttgttcg tcaaaaatta gaatagaagg acaaatatat
     2161 gtgccaaaag aggttatgac aagatttttg tcacaacctc taattcaagg tgttcaaaag
     2221 ccagattctc agcattaagt caaattcaca caaaaatgtg gaaaggaact ttcaaaaaaa
     2281 ttttatattt attctatcaa aaaattttgt ttatgatggt aactgaataa actttcctga
     2341 gatggtcaat gctttccttg aaagtcttac agatattctt tcttcataga aagtttaagt
     2401 tttatagtta gtgtacaata aaagtatgtt tataccatat ggtgtccgga taatcagtca
     2461 tttaaacaat gaggttcaaa gatatgaaaa ggggaaattt gatgaagaaa ataagcaatg
     2521 aaatccaaat tctggcagaa actttaactc ttcccaaagt cgttatagag caaatgattg
     2581 tacaagcaaa aaacatcctt gatgaggtgt ttgagcaata tagtcatgaa ctaatggatc
     2641 ctaataaagc aaaggcgact gcaaagaaaa tagacaaagt ctatgaagag gaaccttttg
     2701 cagcattagc tatttatcta tatgcagctt ctcaaagttg gaaaaaaatt tatcaaccat
     2761 tgaagattcc aagaactatc tatttggcaa caatgaatgc ttttactaga tttattcatg
     2821 aacatttcca agtaacagga agctatcgct ttgaccgtgg tttttggatt tggcattaca
     2881 ctagtggctt gatctttcgg attggtgaat tggagtacga aatgacatat tttccgaaag
     2941 ggtacacgga tctaagatta gaaggaaagc agtgcctttc tcttcatatt ccttccgatg
     3001 cagatttatc tcagaataag ataagagata gttacgaaag tgccattcgt ttttttgaac
     3061 tttattttcc tgattaccat taccaagtga tgtacacaga tacttggtta ctatcaccca
     3121 atcttactaa atagttgaaa aaagagtcaa aaatctgtct ttttgcagcc gattatcgat
     3181 tattatcagt tgatgaacag gacgatagtg gagtcccttg gatctttgga cgagtagatg
     3241 cccaaataca tgattatcca gaaagtacga gtttacagcg acaagcaaaa gagcaattgc
     3301 ttgcaggcga gcacattggc tctggcttag gtattcttac ttcataagtt tagtacttcg
     3361 aaatagttta aaagagcgtg agacaaaagt aaagaacact tttgtctcac gctctaaaca
     3421 cgtataaacg gcggaagcag aagcaactcc ttcggaaata agctgaaatt cacaaaaatt
     3481 tgaaaagcaa ttttcgtgaa tttcttctta tttcttggag ttaaacgctt ctgtcccagc
     3541 ctctttttta gtgttctatc gaacacacag tacgttcaat aggtaaacta gctataacaa
     3601 tagatattaa agttaacgga caagagggcc ttttttaggt agctaaaacg taataatgaa
     3661 aatttatttc cagagatagg agtcaatcag ctagtctgat cgactgtttt aacaagttga
     3721 ctttcatttt aacttttgat accatttaaa acacaaatcg taattgtttc gatttgtgtt
     3781 ttttagcatg actacaatca aagaagaaag tgggtcgtcc atatggaaaa aacagatatc
     3841 tcaagtgcat accgccgctt gaaaagccca aatatcaaaa cacgaaaacg tgcgctgaag
     3901 atcatcaaag atgtgaaacg gaatagtggg aaaaggtaag aagaaggaaa cttaattaaa
     3961 aaaatagccg aaaaacgttt ttcggctatt ttcaataatc ggtttttgtg taaggtttcc
     4021 gaaagaactg ctgttgattt tccattttta acatatgata aattggtaga atctttcttt
     4081 tcaaattgat accattccct aattccagtt atatagttaa ctacagaacc acaaagcacg
     4141 tacgtttata aaagtattat ctgtagttat ttttcaattc cctttcaacc tcttattttg
     4201 accagtagta ttgatcactt taccttttaa cacctttgtt cgtttttgaa acatttttag
     4261 tcaagaatgg aaacgtaact acataatcaa aggttttgcg aaatatttca tgaaatattt
     4321 catgtagaag cgagcaatac ggttgcaaat aaccattatc gtttaataag cagttacgaa
     4381 agctcccaat atctctaacg ttcagctcac tccatttctt ttcttcaaaa aaatcagtga
     4441 ttcgtatctc tttctatttg tcgaaaaagt taactttaaa aagtaacgcc gaaaaaatat
     4501 gcaaaaaaat aaaaaagcag ttactattgc tagaataaca tcaaggaata ataagttttg
     4561 gttttcagat aatagtcgat aagttgtgta ttggaatttt agatacagta ataaagtatt
     4621 tttcatgaaa ttttgtgaga atcactatta caagtatctt taataaaatt aatggttaag
     4681 gaggaactta aagtagaatg taaatgaata gttgtagtca gtcgattgtg atactagact
     4741 caaagttgca ggaataagtt tttcaatttg tgattggaag ataaaaaatg aaaaagaagg
     4801 gctttttttt atactttgtt gattgtagtg tttattttcc ctctgtttag ccaagtaaca
     4861 ttttctatga ctcaaccagt ttcaagtgag gaacatgata acctttttcg tgctacagaa
     4921 gagtttaaga aatatcagga aaatattgtt ccggagactc cattagctag tgagccaatt
     4981 actgatattg atggaaacca aataggatgg tatatacagt acgaagttat ggtggtaaat
     5041 aatgactcaa tagtaaaaaa tacagtaggc ttagagctaa caccgattga aaaggtgagt
     5101 tcattgttaa cgtatattta tactgatgaa agtgacgaga ctgagatcat tttaacggat
     5161 tactcaaaaa ttgctactga taaaaagtat atattgtgga tgtagacact agtgaaatac
     5221 tttatgatat agaaattgat gaaaatttac tagatgtagc acaagaaatc gatcatcaaa
     5281 agcaggaagc tattcgatat gctggtagaa aagggaaaag aaaatattta ttacgtgaat
     5341 gtagcaaaag ttagagaaga tgaaaatgag tggaaagaat tcaagagtcg ctactcaatt
     5401 aactcgactc cgacatttac agtttacaga gaaggatcga tagaaaaaac tgttttttgg
     5461 actaaagaaa gtggaatgtc tttagctgaa gtagaagagt ttttggatta tgttagtatg
     5521 caacagtaag ggagttctta ttatgaaaaa ttttgacaca tattatgtta ttgttttttc
     5581 gatatctttg ctgttaatat tactaacttt aatgcagtat aaagagtatc cagagtattt
     5641 tattttaact tttgtatatt tagtaagtag ctacacactt ctatataaat tcagaagttc
     5701 ttctagagtt tctaaagttt gtttcttaat tagcttattg attctataat atttttgatt
     5761 tatataggaa attaaaaata ttatagaatc aacactcaga gaacgggttg gtttttaata
     5821 gatttaataa gtactgataa tgaaatttct cctggttggg aaaacgaagt tggttaccct
     5881 gtagaagaat tttttcaaga ttactttgcg gagtatgccg ataggataat gagagattac
     5941 gtaacagata aaactcaaga agtcatcaat caatcccagt cattaaatga attatctgat
     6001 aaggcgaaag aagaagcagt tgccattatt tcttcaggga ttagtgacta tattgatatg
     6061 agtggtgaaa tcaattatgg cgataaagac aaaattgtac gcatgataaa agcttttatc
     6121 aaaacttttg atgtgaaggc agatcttaag tttaatgata cttacctagt aggaaaatta
     6181 attaatatcc ttgggacaga gaaagatacg gaaacgttta tttcctcttt gtctatgttg
     6241 tttacagata agcatttttc aactcagctt ggtggagagg aactagtgga aatcttttaa
     6301 ccattacgcc cagcattaat aaaagtatat caaaaaagta ctcctgatga tttttaagat
     6361 tggtttgaga aataatgtga aaacactatt tttaatgtta attatagata gagatgaacg
     6421 cgtcatatgg ttaaaagaat gaaaaagtca aagatacact gctatatttc actaaggata
     6481 tagcagtgta tctttcatgt cgtttcactg gcagtttttt ataaaaggag gtgtgcattt
     6541 cagttgcttt tctttggtag ttagttgaat cgtttaagaa ttaacggatg tggcagacag
     6601 gtgctctgtc caaaaaccag taaaatcttt gatggttcca tctttattta gctgtgcctg
     6661 ttcaaatact gttttgtttt taccgaatgg atcaattgca ataattgttc cgatccccgc
     6721 acgtttggca gcaagtaatc ctgagtaagc atcttcgata acaagacaat cagccggagc
     6781 taagctcagt ttgtctgccg ctttaagaaa aatatccggt tgcggtttcc cagggaaaga
     6841 gccgtcgtca tagacaatct tgtcccagtc aaaccagcgg gctaaatcga aaatatcaaa
     6901 ataaaaagca acattctctt tgacagtagc cgtggcaatc gttaatggaa tctgttggtc
     6961 agtcagctgg tcaagagtcg cttcaagccc ttttgtcaac tgaagctcgt tttcattttg
     7021 caagcaaagc atacgataat agctttcttt ttcttctgac aatacggcga tctcagaggc
     7081 ggtcaaatgc tctgaaatga aatgtttcaa aatctccgta ttcgtccgac catgaatatt
     7141 ttttaaaata tcctcgtctg ataaaccatc ttttgtatga tcatgtatca tatgcagcca
     7201 agcagcttca tgcagatgag agtccaaaaa cattgttccg ttgaaatcaa atataatccc
     7261 tttcatagtt acgctcctat agtggtattt tcggttgaat cagcaatttg cagatcgaca
     7321 tattgtgcat agtgctcttg aacctcccgc gagatctggc gatccgtaat gagcagatcg
     7381 aaatcatgca aattataaaa cacataaaaa tcatctcgat tgaatttttt attatcaacg
     7441 agtagatatt tcttacggga attatttaga gcgatctgct gtgcttctcc ttcttcggta
     7501 ctgtaagtag agatcgcttc gttgtgaacg ccatttgaac tgataaatgc ttttgtaaac
     7561 tttagtcttc ttaaattgtc gttggtgatc ggtccgacaa atgcgccggt atttttccgg
     7621 aaatcaccgc caatcagtag aatttctggt ccatctgctt gagcaagaat atcaaaaact
     7681 ggataattat ttgtaatgat ccgaattttc ttgttcagta aatgcgtcgc caatagttcg
     7741 attgttgtac ctggtcctaa gaaaatcgtt tctccctcgt gaatcaagga ggctgctgtg
     7801 gcagcaattt cttttttttc ttgaatctgc agagtggctt tttcagtgtg agaaagttct
     7861 tgatctaaag tgtaggaaag actttgagcc cctccatgga cacgcagcag cttgcccgat
     7921 ttttctaatt catctaaatc tctgcgaacg gtcatatcag aaacatctaa ttgattgatg
     7981 atttcattaa cggtaaggat tcctttttta ttgaccattt ctacgatagt aagcaatctt
     8041 tcttttttca acattgtctt cacctctaat ttaaggataa tctatcatat aaacggacaa
     8101 cagtcaatct aattcgaaca aaagtaaaca tttagggtgg tttttatgtt tgttacaata
     8161 gattttattg ctgttttctg gtttttatga ttatttgtgt ttgtttttgt tgacaaatgt
     8221 tttggatgcg tttacaatgc aatcagttag aaagagcgaa aactgattat agatttgagg
     8281 agagatgtac atgcttaaat taccagaaga ttttattttt ggcggagcca cagcagccta
     8341 tcaggttgaa ggagccacta aggaaggtgg caaaggcgct gttgcttggg atgacttttt
     8401 agaggaacaa gggcgattca gtcccgatcc ggcaagtgat ttttatcatc aatatgcaaa
     8461 ggacattgaa ttgtgtgaac gttttggtgt aaatggtcta agattatcca ttgcttggag
     8521 ccgcattttt cctgatggag ctgggaaacc aaatccagaa ggaatcgctt tttatcatcg
     8581 tgtgttcgaa gaatgtaaga aaagaaacgt aacgccgttt gtgacgttgc atcattttga
     8641 tacccctaaa cgtttgtttg accatggaga ttttttgaat cgagaaacaa tagaagcatt
     8701 tgtttcctat gccatttttt gttttcatga attcaaagaa gtcaaggtgt ggagtacctt
     8761 taatgaaatc tatccagttg caaccaatca atatttgtta ggtgttttcc caccaggaat
     8821 caaatatgat tttacaaaga tcgtcgcctg tcttcataat atgatggttg ctcatgcccg
     8881 tgtagtgaac tatttcaaag aaaacgaact tccgggtgaa attggtgtag ttcactcatt
     8941 agagacgaaa tatgcggcaa cagacgcgcc ggaagataag catgctgcct ttttagacga
     9001 tgcattgtcg atccgtttct tattagatgc tacctattta ggctattatt caactgaaac
     9061 cttgactgct cttgatgaga tatgtgaagc aaatcaggcc agctatcatt ttcctgaaga
     9121 agatttcgtt gaattgaaaa aagcatccac gcgtaatgac tacttaggga tcaatcacta
     9181 ccaatgccat tttgtcaaag cttacgatgg agaaaatgca atccatcata acggtacggg
     9241 tgaaaaaggg acctctgttt ataaagtgaa gggaatcgga gaacgtattt ataaagaagg
     9301 aattcctcga actgattggg actggctgat ttatccagaa ggtctatatg acttgttgct
     9361 gcgaattaaa agcgattacc cacattacaa caaaatctat atcactgaga acgggatggg
     9421 gtataaagat cagtttgaag atggcattat tatggatcag ccgagaatcg actatttgag
     9481 agtctatttg gaatccttaa gcaaggcgat aacagccggg gtaaatgtga aggggtattt
     9541 tttgtggtcg cttatggatc ttttctcatg gacaaatggg tataacaaaa ggtatggctt
     9601 gttttatgtt gattttgaaa cccagaagcg ttacccaaaa gaatcagctt actggtacaa
     9661 gttggtcagt gaaaccaaaa cgattattta ataagtgata atggaggaag aaaagatgaa
     9721 taaagaggaa ttacaaatgc ttggttttga gatcgttgca tattcaggcg acgctcgcag
     9781 tacattattg aaattattga aagaagtaag acaaggaaac tttgaacatg ttgattcggc
     9841 gttgaaagaa gccgacgaaa atttaaccct tgcacataat tcgcaaacaa aaattttagc
     9901 ggaagaagca tctgggaaag agatggagat gggattcatt tttatccatg ggcaggatca
     9961 tttaatgacc actttattgc tgagagatct gattcaagac tttattgtac tgtacagaca
    10021 gaatcaagga taggagaaga acgctatgga tggaatcatt aaacaaatcg aaaaagggaa
    10081 accatttttt gaaaaaatct cacgtaatag ttatttagga gccgttcgtg acggattttt
    10141 aacagcgatg ccagctattt tattttcaag cattttcatt ttgattgctg cggttcctga
    10201 gatttttggt taccaatggc ctgaatctgt ctccacatgg ctatggaaag tctataatta
    10261 ttcgatgggt gttgtagggt tactcgtttc agcaaccact gctcgctgct tggctgattc
    10321 gatgaatcgt cgcttaccga aaaacaaagt aatcaacacc acctctgtga tgctggcctc
    10381 tgtggtaagt ttcctgttgt taagcgtctc tccgattgaa ggtggatttt caacggaata
    10441 tatggggaca aagggactac tggcttcctt tgtcgctgca tttttaacag ttaatttata
    10501 taagttttgt gtgctgaaag atattaccat taaaatgcct aaagaagttc ctggaacgat
    10561 ttcgcaaacc ttccgagata tttttccttt ctctttttca gtatttgcgg ccgttttaat
    10621 tgatttaggc attcgacaaa tcttccaaat ctcatttgca gaagcaatca ttacggtgct
    10681 gcagccgcta tttacagcag ctgacgggta cttaggaatc gctattatct ggggagcgat
    10741 ggcgctgttt tggtttgtcg gtgttcatgg accgtcgatc gtggagccgg caattgcggc
    10801 aattatctat gccaatgtgg aaaccaatct gcaattgttc aattccggtg aacaagcttc
    10861 taaagtactg acggtgggtt tagggaattt tgtaggaact atgggaggaa ctggggcaac
    10921 attggttgtt ccttttatct tcctactctt tgctaagtct aagcagttga aggcagttgg
    10981 gaaagcttcc tttattccag taagtttcgc tgtcaacgaa ccattgctat ttgcggcacc
    11041 catgattttg aacccttatt tttttattcc atttttgtta acacctgttg taaacgtttg
    11101 cctgttcaag ttttttgtcg atgtattggg catgaacagc tttatgtacg ttttgccttg
    11161 ggcaactcca gcaccgatcg gtttggttct aggaacgggc atgggtatct tagcttttgt
    11221 tctagcagcg gttctaatcg tcgttgactt cctgatctat ctaccatttt gcaaagcata
    11281 cgatgctgtc ttagtagaga aagaagcaca aaaagcagag gtgatcgcaa ccgaggaagg
    11341 tgcttctgcc gatgtacgtg aggaagtacc tgtggcagcg agtcaagtta tcagcgatgc
    11401 aaataaagaa atcaatgtgt tggtactttg tgctggcgca gggacaagtg ggatgttagc
    11461 taatgcttta aaaaaaggtg catctgaatc gaaagcaccg atcagtgcaa tggcgggtgc
    11521 ttatggttct cattacgaaa tgctgcagga ttttgatatg gtggtcttag caccgcaagt
    11581 caattcttac tatgatgata tcaaagaaga caccgatcgc ttaggaatca agctggttgc
    11641 gacaaaagga gcagaatata tcggattaac gagagatcct gaaaaagctg ttcagtttat
    11701 tctgaaccaa tttcaataaa ggaggagcca taatgaaaat gggaatttgg ttgcgtaaag
    11761 ctgttttatt tgcagctgtg ttaggggctt tgggggctgt ttcaaaaact gttgaagcat
    11821 ctgccagcga atttattcgc ggagcagata tttcgatcct gtcagatatg gaaaaatctg
    11881 gtgcaaaata ttatgaagac gatatttcaa aagatgcctt agagatttta aaaaataatg
    11941 gtgtcaacta tgttcgactg cgtttgtggc aggatcctta taatagtaat ggagaaagtt
    12001 atggagcagg gacaaatgat ctggaaacga cgattgacct tgcaaaacga gcaaaaaatc
    12061 tgggacttaa ggtgctgctg gattttcact acagtgattt ttgggttgat cctgggaaac
    12121 agaatcttcc taaagcatgg caaggtctga cctttgaaga aatgaatacg gcattgtacg
    12181 actatacaaa gaacgttctg tcggaaatga agcagctgga cgtttatcct gatatggttc
    12241 agatcggcaa tgaactgaat agcggaatgc tctggcctta tggcaagtct tggggagaag
    12301 gcgggggaga atttgatcga ttggctgctt ttttgaagtc tggtatccaa gctgttcgag
    12361 acactcaacc taaaacaact ccagtaatgc tccacttagc tgatggtggc gatacaggag
    12421 catttacttg gtggtttgat gaaatcacga gtcgaggtgt gtcatttgat ttaattggag
    12481 tgtcgtatta tccgtattgg cacggttcaa tgaatgaact tcaaaccaat atgaatgcga
    12541 tcagccaacg gtatggtaaa gaagtgatcg tagttgaaac agcttatggg catacaacag
    12601 cgaatgccga tactatgcca aatgcttttg gtgaagccga agcagctgcg gggggatatg
    12661 aaccaacacc gacaggacaa gcagagtatt tgctggatct tgccgatcgg attcaggcag
    12721 taccgaataa tcgcggggcg ggcttcttct attgggaacc tctttggtac aacggaaatg
    12781 tgagttgggc aacacaagca ggtatgaatt atctcagtgt tcaatccact atgggaaacg
    12841 aatgggacaa ccaagcgatg tttgattttg ctggaaacgc cttgccaagc ttgcgtgcgt
    12901 ttaaacaagc aggggcgcaa ataaatctag ttaaaaatgc aagtttcgaa agcgatggac
    12961 caacgaccag tccttccaat tggcaaacct ggtttcaaca aggaaccgct aagggtacga
    13021 tcaaaacgga agcgggcact ttttttgggg actacaaact aactttttgg caggatcaag
    13081 catacgaggc atcagcttat caaaatgtta gtggcataag caaaggaact tacacattga
    13141 gtgcctatgt aatgtctggg ggagagtttg atactaatca gttatatatc aaaaattatg
    13201 gtggagcgga actaaatact gcggttgtta aaacaagtga atggacaaaa attacaatca
    13261 aagacattcc aattacaaca ggtgtttgtg aaattggggt ttatagcaag gcttcaggaa
    13321 atgcttggac gaacgttgat tttgtttcat tggtgaaaca atagactgcg gatcgtttcg
    13381 attcaagatc ggaggttccc ttcagccaca tcgttagcgt agaaggcagg aatcgaacct
    13441 gcacctcgcc tttgccaaaa ataaccagaa acgatttcca gtcattttta ccaaaacgag
    13501 taaagcacca gacttcatct acactttgta ttatgctaaa gagagttcaa cgatttcgta
    13561 agaagcaatg aaaaaattgc aaaaagttgt gcagataaca taaagtttgt ttaagaaagg
    13621 gtaaccttag aattccgtcg tgaatatgat ttgagcactt agatggatag aaaaaagttc
    13681 tcggaaaaca gttcgttttt cgagaacttc tttttatgat aagaatgaaa caaattaact
    13741 tatattatag tctcttttgg tagggaacca tcttattttt aatgaaaatc aagcatttta
    13801 gctattgaag aatgttgatt tatagggatt ccccctccat attatgttgg ctctttattc
    13861 ccactccact gttgctggtg gtttagaagt gatgtcatac acgatacggt tgacgtgggc
    13921 tacttcgttt acgatacgta cagagatttt ttgcaagact tcccatggga tacgggcaaa
    13981 gtcagcggtc attccgtcga ttgaagttac agcacggata ccgactgtgt agtcgtaagt
    14041 acgtccgtca cccataacac cgacagagcg gatccctgga agaacagtga aatattgcca
    14101 gatatcacgg tcaagtccag cagctgcgat ttcttcacgc aagatagcat cagattcgcg
    14161 tacgatttct agcttgtctt cagtgatttc gccaagaaca cgaataccaa gaccaggacc
    14221 agggaatggc tgacgccaaa cgattgaatc aggcatgcct aactgagtcc ctaattcacg
    14281 gacttcgtct ttgaataatg tgtttaatgg ttcgatcaat tcaaattgca tatcttctgg
    14341 cagtccacct acattatggt gagatttgat cgtctgtgct gtttctgtac cagattcgat
    14401 aacgtcagta tacaacgttc cttgtgctag gaaagagacg ccttcttcac cagcaagttt
    14461 tgttgcttcg tcatcaaaaa catatacgaa ttcattccca atgattttac gtttttgttc
    14521 tgggtcagat acacctttca acttgtctaa gaagcgatct cttgcattga ctttgatgat
    14581 gttcaagccg aattttccgc ctagactttc cattacttgt tccgcttcgc ctttgcgtag
    14641 cagaccgtgg tcaacaaaga tagatgtcaa ttggtcaccg atcgcttttt gtaaaagaac
    14701 cccaacgaca ctagaatcaa cgccacctga aagaccaagc aagacttttt tgtcaccaac
    14761 ttgttcacgg attttttcta cttgcatatc gataaagtta tccattgtcc agttaccttc
    14821 acagtgacaa acatcaaagg caaagtggcg cagcaattcg attccgtatt cggaatgacg
    14881 tacttctgca tggaattgga taccataaaa attacgtgtt gtgtcttgga tagaagcaat
    14941 cggacaatct ttgcttgttc cgactgtttc aaagccttca ggaactttag ttaccaagtc
    15001 accatggctc atccatactg tttgttgttt tggtgtttct ttaaacaaga cagcttgatc
    15061 gcttgttact tctaacaagg ctttcccata ttcgcggttt ttagcaggct ctacggaacc
    15121 gccaagtttg tacgtgatca attgcatacc atagcaaatc cctaatacag gaatacctaa
    15181 attgaagatc tcaggatcga tcccaaatgc attctcatca tatacactgt ttggtccgcc
    15241 agaaagaatg attccctttg gattcatcgc ttttacttct tctgcagtaa tgcggtggct
    15301 caataattcg gaaaagactc caagatcacg aatacgtctt gtgatcaatt ggttatactg
    15361 actaccgtag tctaatacga taatcttttc aacgttcgtc atatcggcaa cgtttgtcaa
    15421 atttattacc cctatccctt taaattttat ctcaaaatag tcaaactatt ttaaaatgct
    15481 aatattttcg catgaaaatc gaatcgatga tatgattttc agttttatgg agaattatat
    15541 cggctcttcc tcgtgtaggc aagatatatt cctgtaaatt tttcaaattc acatttttcc
    15601 atacatcttt tgccatttta aaggcttctt cacgatctcc gatagcaaaa cgataataat
    15661 aattctctgg attttggaaa gccgtatcca gtaacgcacc aaaacgatcc aaataccatt
    15721 tttcgatcag cacgggatcg gcatcgacat agacagaaaa atcaaaaaag tcgctgacgt
    15781 agatttgctg attcgcaggt aattgaagcg tattgatccc ctcaacgatc aagatatcag
    15841 gctgctggat caattcgtac ttgtctggaa tgatatcata cacatcatgt gagtaaacag
    15901 gtacttttat ctcttcctga ccagatttta cacggttcaa gaaatcgatc agcatctcca
    15961 tatcataact ttcaggaaat cctttacggt ccatgattcc acgctctttt aatatacgat
    16021 ttggataaag aaatccgtca gtcgtgatca gctgaacgtt tcttcgtttg aaggtacgag
    16081 acaaaatcgt ctgcagcagt ctggctgttg tactttttcc aacggctaca cttccggcga
    16141 tcccgataat aaaaggcggt acttctacgt atttatgaag aaataaacct ttactcaaga
    16201 acaaagattc aaattctttc atataaagat aaatcagatg agcaagaggt acatagatat
    16261 ctcgaacatc ctgcatggaa atgcggtcat tcaaactttt gatattatct agttcatctt
    16321 gtgtcaaagg tgcttgccca ttacgataaa attctcgcca ttcttctctt gccacacggt
    16381 agtagttcat tggatcattc atattagcct cctgcgttct cccatcaatg gaactatttt
    16441 aacacaaaat aaacgcaaac cccaccactt aagagagatt gccgatcttt ttgtataatc
    16501 tttataatag aaagaaacgg agtcttattc ttgacttgcg cacggataca taaaaggata
    16561 gactgttgtc atgaaagaaa tgagaaggat ggaagacatg acaaatcatt actattctga
    16621 acgcccagat acggcgcacg attttgaaca atgggctttt gagttaaaag gcagaacctt
    16681 tcaatttgta acagattctg gtgtattttc acgtgaaaca gtggattatg gttcacgtgt
    16741 cctgattgat gctttcgatt gggaagagtt acctgatgaa ggaaagatct tagatgtggg
    16801 atgcgggtat ggaccgattg ggttagcttt ggcatttgcg acacagcggt ttgttgaaat
    16861 ggtcgacatt aatgaacgag cggtaagtct agcgcaagga aacgcaaagc gtaaccaaat
    16921 cgaacatgtt gatatccatc aatcgaatat ctatgaagca gttcatgaag aaacctatgc
    16981 agctatcgta agcaatccgc cgatccgtgc tggaaaaaaa gttgtacatg aaattttgac
    17041 aggcgcatat cctcggttga agaagggcgg tacactgaca attgtgatcc agaagaaaca
    17101 aggagcgccg agtgcgcaaa agaaaatgga agaaacattt ggtaatgcag aaatcgtcac
    17161 aaaagataaa ggatattata tcatcaaaag tgtgaaagaa taactagctg aaaaatagtg
    17221 gagcgacgaa agagtggaac tgggcgtgca tgtacgggta cgtatcagtt ctttttttgt
    17281 tgagaagttt ttaaaaacaa agaactattt tttcttcaaa aagaaatagt aggaacagag
    17341 tcgttgtttt ttacgataaa ataaataaga tacagaactt gtatagaagg ctgccaagtc
    17401 ggtagataaa ggaggttttt atcaaaaaac atactttcct tttttctcta ttcttttctt
    17461 gggggttttg gtacactgat agggaattta gatagaaggg agccaatagg atgaagctga
    17521 ccatcagaga tatcgcagaa atggcaggcg tatcagtaac aactgtctca cagattttga
    17581 ataacaaagg aagcagattt agtgataaga caagaaaaaa agtgttgtcg atcgtgaatg
    17641 aacatcatta taagcccgat tatttcgctt caaatgtgat caatcgacat tcaaagacca
    17701 tcggaatgat cgtccctgat gtcactgatt tcttcttctc caaactgatc gaaggtgtag
    17761 agagctattt gaatcctttg ggctatgtga tcatgttatg caattctcgt catagccaag
    17821 aaaatgagat caagtattta caagagcttt cccaccgctc agtggacgga atcttgctgg
    17881 ccacaccaaa tattttacct gagaaatatg cattagacag cggtttttat caaaaaatgc
    17941 caatcatttt aatcgatcgc ggattgaatc gtcgggataa cggacggctt atcgtaaagg
    18001 aatatgaggg cgcctatcaa gctgtttcgc tgtttattga aaatggccat acgaagatcg
    18061 gcatgctgaa ggaaaccact ggatactatc aattagaaga acgtttcaac ggatatcgtc
    18121 atgcgctgaa agatcatggc ctgcctttta atgggaaatt tgttgaacat ggagagttga
    18181 ctgtccaagg tggatatact gcatcaaaaa aattactcaa acataaagat atcacggcta
    18241 ttttttgcgg gaatgatgcc atggcgatcg gatgctatca ggcgatcgat gaattgggca
    18301 aaaaaatccc agaagatatc tcagtcatag gattcgatgg attaaagctg tcagaataca
    18361 tgattccgca attgacgaca gtgcagcagc caagttttga tattggattt tatgctgcac
    18421 gtttcctgat cgatacgatc gaatttcctc aaagaaaagt tccgaacaaa gtgttcgaaa
    18481 caaaattaat tattcgtgag agcgtaaaag tattgacaaa gggctaactc ggcggtatat
    18541 tgcttatgta agcatttaca aaggctagtt agtgcttttt ttatttttag taaaccagtt
    18601 tactaaagtg gtttaccttt cctaaaaata atgtataata ccgaatgaag acaaggagga
    18661 tcaggcaatg cgaatggtgg atctgattga aaaaaagagg gatggaaacg agctgtcgaa
    18721 agaggaaatc gagtacatcg tcacgaacta tacgaatgga aagattccag attatcaagt
    18781 cagtgcatta ttgatggcaa ttttttatca agacatgaca aatgaagaaa tcacgaactt
    18841 aacattggcg attgctaatt ctggtgatgt catcgatttg agttctcttg aaggaataaa
    18901 ggtagataag cattcgacag gtggcgttgg tgacacgacc acattgattt tagcccccct
    18961 agtagctagt gtcggagtga cagtggctaa aatgtctgga cgcggtctag gttacacagg
    19021 tggtacacta gacaagctag aagcaattcc cggatttcag atcgagcttt cggatgaaga
    19081 atttgtacgc attgttaatg aaagtaaagt agcggtaatt ggtcaatcag gaaacttggc
    19141 accggcggac aaaaaattgt atgccttgcg tgacgtcaca gcgaccgttg attctcttcc
    19201 gctgattgcc agttcgatta tgagtaaaaa aatcgcggca ggagcagatg caatcgtttt
    19261 ggatgtgacc actggagacg gtgctttcat gaagaacatc gaagatgcaa gacgtctggc
    19321 aaagaccatg acgagcattg ggaaactggc taaccgagaa acagtggcgg ttatctcaga
    19381 tatgtcagaa cctcttggcg aagctatcgg aaatagtcta gaagttgtcg aggcaatcga
    19441 aacattacaa ggaaatggtc cagaagatct agtagaaatg tgctacgcct taggaagcca
    19501 aatggttgtt cttgctggca aagctaagac aaccgatgaa gcaagaacgt tgcttcaaga
    19561 agctctggaa tcaggtaaag cgttagcaaa attcaaagaa atgatccaaa atcaaggggg
    19621 agacccagcg atcgtggaac atccagaacg aattttgact gcacgctaca caatggagct
    19681 tcctgctaaa caaagcggag ttgtgtcaaa aatcgtggca aatgaattag gaattgctgc
    19741 aatgatgcta ggtgctgggc gtaaaaccaa agaagaagat attgatcacg ctgttggatt
    19801 gaaactgcat aaaaaaattg gtgacactgt gacaaaaggt gagtcactat tgacgatcta
    19861 tagtaacgac gaagaaatca cttctgtcat tgaattatta tataaaaata ttgaaattgg
    19921 tgaatcggca atgaagccaa cgttgattca tgacatcatc acagaataaa ggaaaaaagc
    19981 ggactttacc gttttaaaga aaaggggaaa agaaatggaa ctaaaccgaa tgatcgacca
    20041 tactattttg aaagcagacg catctaaaga agctgtgatg caaattatcg aagaagcaaa
    20101 aaaataccat ttttattctg tctgcatcaa tccagcatgg gttgcgctag cgaaagaaca
    20161 attacaaggt gagccagtag ccgtatgtac agtaatcggg tttcctctag gagcaaacac
    20221 acccgagaca aaagcatttg aaacaacaga tgccatcaat aacggtgcag atgaagtcga
    20281 tatggtcatc aatatcggtg ctttgaaatc aaaggatgat caacaagtcc aaaaagatat
    20341 cgaagcagtt gttgaagcag caaaagatcg tgcgcttgtc aaagttatta ttgaaacatc
    20401 gttattagat agagaagaaa tcatccgagc ttgcgaaata gcaaaagctg caggcgctga
    20461 ttttgtcaaa acatcaactg gtttctcaac aggcggagca aaggtagagg atgtccgttt
    20521 gatgcgtgaa actgtaggac cagaaatggg tgtcaaagct tccggcggta tccataacga
    20581 agaagaagca atggcaatga tcgaagctgg tgctacaaga atcggaacaa gcgcaggagt
    20641 agcaatcgta tctggttcaa ctggtgaagg ctattaattt tttcaaagga gaagctcatg
    20701 gcagaactca aacaagaatg gatcaacaca gctattgaag cgttagataa agcctatgtt
    20761 ccttattccc attttccggt aggcgcttgt ctcgtaacgg aatcaggcaa gatttatcaa
    20821 ggcatcaaca ttgagaatgc atcatttgga ttaacgaatt gtgccgagcg cacagctttt
    20881 ttcaaagcag tatctgaagg agaaaaaaca tttacgcatc tagtcgtagc ggggcacacc
    20941 cccgatccta tctctccttg tggtgcatgt cgacaagtaa tggcagaatt ctgttcccct
    21001 gatatgccgg ttacgctagt aggagacaat ggtgtgacga aggcaacgac cgttcgtgca
    21061 ctgctgcctt atgcatttac tgaaaaagat ctataactca tgttcattca gtcagctgac
    21121 tgttgaaaaa taaaacaatt attttaggag gctttacaga aatgaaaaaa gcaaaattat
    21181 ttggtttagg tgctgtcgca ctagcagcag ggttattttt aggtgcatgc ggcaacaacg
    21241 gctctactga ttcatccggt ggcaaaagct catcagacac aacaactgca gcattgatca
    21301 cagacacagg tggtgtagac gaccgttcat tcaaccagtc agcttgggaa ggactagaaa
    21361 aatgggggaa agatcaagga ctttcacgag gaaatgatgg cttccaatat ttccaatctt
    21421 caaatgaatc agattacatc ccaaatattg accaagcatt gaatgctgga ttcaaaacga
    21481 tttttggtat tggttataaa ctaaaaccag cgatccaaga acaagcaaca aacaatacag
    21541 gtacgaactt tgttattatc gatgatgtca tcgatggatt agataacgtt gtatctgcaa
    21601 ctttcaaaga caacgaagct tcttatcttg caggtgttgc agcagcttat acgactgaaa
    21661 caaacgtagt cggctttatc ggcggtgtaa aaggtgaagt aatcgatcgt tttgatgctg
    21721 gattcaaagc cggtgttgat gcaggtgcga aagaattagg aaaagaaatc aaagtattga
    21781 atcaatatgc tggtgacttc tctgctccag ataaaggacg ttcaattgct caaggtatgt
    21841 atgcacaaaa cgcagatatc atcttccatg cttcaggcgg tacaggtaac ggtgtattcc
    21901 aagaagcaaa atcattgaac gaatcaggcg acaaaaaagt ttgggttatc ggtgttgacc
    21961 gcgaccaatc agacgaaggc gaatacacat taaacggcga aaagaaaaac ttcacattga
    22021 catctacact gaaagcagtt ggaacagtag tagaagattt ggcacaaaaa tcagcggacg
    22081 gtaaattccc tggcggcgaa cacactgttt atggattgaa agaagacggt gttggtctaa
    22141 cagaaggaca actttctgac gaagcgaaaa aagcagttga tgaagcaaaa gaaaaaatca
    22201 tttcaggtga cgtaaaagtt ccagaaactc ctgaagaaaa ctaaaaccat ttctatagcc
    22261 ttgttagaca catgtttgac aaggctatgg tttgattaga acaagaattg ttcatttatc
    22321 caagctgcct tgtgacagtt tggataaggg aacaactccc tgaagtaatg tttgtttcaa
    22381 aagaagaacg ctcactaagc gtgaatctta gtcaatcgtt gccctagata gaaatcgtta
    22441 ggatgtgaaa aaaaggtggt tcaagaaaat attgtcatag aaatgcagaa tattaccaaa
    22501 gaatttggaa cattcaaggc aaatgacaac atcaatttac aagtaaaggc aggagaaatt
    22561 catgcgttgc ttggagaaaa cggtgctggc aaatctacat tgatgaacgt gctttccgga
    22621 ttattagagc cgacatcagg gaaaattttg atgcgtggga aagaagtaaa gatcacaagt
    22681 ccgaccaaag ccaaccaatt agggattggg atggtccatc agcactttat gcttgttgat
    22741 gcctttactg taacagaaaa catcgtgttg ggaagcgagc ctagtcgcgc agggatgctt
    22801 gaccataaaa aagcacgaaa agagatccaa aaagtttctg aacagtatgg attgtcagtc
    22861 aacccagatg cttacgttcg tgatatttca gttggaatgg aacaacgggt agaaatttta
    22921 aaaacacttt accgaggagc agatgtactg atttttgatg agccgacagc tgtattgacc
    22981 cctcaagaaa ttgatgaatt aatcgtgatc atgaaggaat tagtcaaaga aggcaagtcg
    23041 atcattttga ttacgcataa gttagatgaa atcaaagcag tagctgaccg ctgtacagtt
    23101 atccgccgtg gaaaaggaat cggtacagtc aacgttaaag acgtaacctc acaacaatta
    23161 gccgatatga tggttggaag aacggtttca ttcaaaacga tgaaaaaaga agcgaagcct
    23221 caagaagtcg ttttgtctat tgaaaatcta gtggtgaaag aaaatcgtgg attagaagcc
    23281 gtgaaaaact tgaacttaga ggttcgtgct ggcgaagtac ttggtatcgc tggaatcgat
    23341 ggaaacgggc agtcggagtt gatccaagct ttgactggtt tgcgaaaggc agaaagcgga
    23401 catatcaagc taaaagggga agacatcact aataaaaaac cccgaaaaat cactgaacat
    23461 ggtgtaggac acgtgccaga agaccgtcat aaatacgggt tagtcctaga tatgacatta
    23521 tctgaaaata tcgcactaca aacctatcat caaaaacctt acagtaaaaa cggcatgctg
    23581 aattattcag taatgaatga acatgccaga gaattgatcg aagaatatga tgttcgaaca
    23641 acgaatgaac ttgttcccgc aaaagcttta tcaggcggaa atcagcaaaa agcaattatc
    23701 gctcgtgaag tcgaccgaga tcctgatctg ttgattgttg caaatccaac tcgtggactg
    23761 gatgtaggtg cgatcgaatt tattcataaa cgtctgatcg aacaaaggga caaatacaaa
    23821 gcagtgttac tgatcagttt cgaattagaa gaaattttaa atgtttcgga tcgtattgct
    23881 gttatccatg aaggagaaat tgtcggtatc gttgatccga aagaaacatc tgaaaatgaa
    23941 ttaggtctat tgatggcggg ctatacctta gaagaagcac gaaaagagtt agaaaagggg
    24001 gctggcgcac atgaatgatc gcagcgaaaa attccgtaat ttattagtgc ctgtactttc
    24061 agttgtttta ggattgatct taggcgcgat attgatggct gcttttggtt ttcagcccat
    24121 ccaaggttat tcttctatgc tagatgcagc ccttggttcg caaagaggga taggtgaaac
    24181 gttaaggcaa gcaacgccgt tgatttttac agcattaggt ttttctgtag ctaactcagc
    24241 tgggtttttc aatattgggc tttctggaca agcactttgc gggtggatcg tcagtgtctg
    24301 ggtggcactt gcgtttccag atctgccaaa agttgttttg cttccgttat gcgtgatctt
    24361 aggtgcctta gctggtgcga tggcagcggc tgttccaggt ttacttcgag cattttttgg
    24421 aacaagtgaa gtgatcgtaa caatcatgat gaactatatc ttattatacg taagcacatt
    24481 tgctttacat gaagtgatgc ctgaaagcta tcgctcaagt ttggactctt ccaatatgat
    24541 cagtcaaaat gcctcactgc ggttaccatg gttaacacaa gcttttggcg gctctcgcgt
    24601 aaactcagga ttatttttag caatcatcgc gcttattttc gtttggctgc tgatgaagaa
    24661 aacgacttta ggatttgaaa tccgttctgt tggattgaat ccttttgctt ctgagtatgc
    24721 aggaatgagt agtaaacgta cgatcgtttt gtcgatggtc atttctggcg ctttggcagg
    24781 gcttggcggt gtggttgaag gattaggaac gtatcaaaac ttctttgttc aaacgacttc
    24841 gctatctatt ggatttgacg gaatggctgt ttccttgctt ggttctggat cagcaatcgg
    24901 tattctttta tcagcgatct tgttcagtat tttgaagatc ggtggacttg gcatgcagac
    24961 aggagcaggt gttccgtttg agatcgtcaa tgtatcgatt gctttgatta tcttctttgt
    25021 cgggatcaac ttcctgattc gtttcgtcat ggctaaagtc ttccaaggga aaaaacaaga
    25081 agagatcgtt gcgacaatag aatcgaaacc aacgaatcaa aaccatgaag ggggcgaact
    25141 ataatgtcga ctatcgaatt aattgccttg atccttactt ctacactggt ttattcaaca
    25201 ccgctaattc taacgtcact aggcggaact ttttctgaac gaagcgggat cgtaaacgta
    25261 gggctagagg gaatcatggt catgggtgct tttagttcca tcgttttcaa cttgacgatg
    25321 agtccatcac ttggttctat gacaccatgg atcgctattt tagtgggtgg cgtcgtaggt
    25381 atcctatttt ctctgattca cgcagtagca acagtcagtt tgcgtgctga ccatattatc
    25441 agcgggacag taattaatct gatggcacct gctttaggtg ttttcttgat caaagcatgg
    25501 tatggtaaag gtcaaactga taacatcacg cagaatctgg ggtatttttc tttcccagga
    25561 ttagcagata ttccggtcat tggaccaatt ttctttaaaa atacattctt acctgcttat
    25621 tgtgctattt tgattgctgt cctagcttgg gtgatcatct tcaagacgaa attcggcttg
    25681 cgcctccgtt cagttggtga aaatcctcaa gctgccgaca cattaggtat caatgtatat
    25741 gctatgcgtt attcaggcgt actgatttct ggcttgttag gcggtatggg cggtgctgtt
    25801 tttgctcagt cgatttccgg taacttttca gctggtacga tcgttggaca agggttcatc
    25861 tccatggctg ctatgatctt tggtaagtgg aatcctttag gggcaatggg tgcctcattg
    25921 ttctttggtt ttgctcaaag cttgagtatc attggcgcac aattaccagt tatttcttcg
    25981 attccgccag tattgctgca aattgctcca tatttgctga caatcattgt gctggttgtt
    26041 ttcttaggga aagcttctgg tccaaaagca aacgggaaga actatatcaa atcaaaataa
    26101 tcttttagcg aataaaaagg gtgggttacg ggaagtgttt ttcgtctcgc cctttttgtt
    26161 ttaaaggcaa taaaaataaa aagaaagaag gaataatcat gtttaaacgc gtacatctga
    26221 tcgtcatgga ttcagtagga attggagaag caccagatgc cgataagttc ggtgatgttg
    26281 gttctgatac attaggacac attgcgaaag aagcaggatt gaacgttcca catttagagc
    26341 agcttggttt aggaacgatc cgtcctcttg aaggtgtgga atcagtgaaa gatcatcaag
    26401 gctatgcgac gaaattagaa gaagtttctg tagggaaaga tacgatgaca ggccactggg
    26461 aaatcatggg attgaatatc aaaactccat ttcgtgtgtt tcctaatgga ttccctgatg
    26521 atctgatcaa acaaatcgaa gaattttctg gccgtaaagt cgtatgtaac aaaccttata
    26581 gcggaacagc tgttattgac gattacggtg aacaccaaat gaaaacaggc gatttaattg
    26641 tatatacttc tgccgatcct gtccttcaga tcgcggcaca tgaagaaatc attcctttag
    26701 aagaattata tcggatttgc caattcgttc gtgatataac aaaagatgat ccgtatatga
    26761 ttggccgaat cattgcacgt ccgtacgtgg gtgaaccagg agacttcaca cgaacaagca
    26821 atcgccatga ttatgcgttg aatccattcg gacacacagt ccttgattct ttgaaagaag
    26881 caggaaagga cgtgattgct gttggaaaga tcaacgatat tttcaacgga caaggaatca
    26941 ctgaatctgt ccgcacgaaa agcaatatgg atggcgttga ccagctgctg aaagttatga
    27001 aaaacgattt ttcaggaatc agctttacca atttagtaga ttttgatgca ttatacggtc
    27061 atcgtcggga tgtagtcggc tatgcgcatg cgattgaaga atttgactta cgaattccag
    27121 aattgcttga agcgatggaa gaagacgact tgctaatgat tacagccgat cacggaaacg
    27181 atccgacgtt tactggtacc gatcatacgc gagaatatgt accgttattg gtttacagta
    27241 aaaaaatgaa agaacaaggg gcattgcctc aaggatatta ttcagatatt tcagcaacga
    27301 ttgctgagaa ctttagtgtt tcttcgactg aaaatggcga aagcttcttg aaattattaa
    27361 aataatcttt ttaaatagga gaaagcaaat gaccaagtta agcgagatgt tacaagaaac
    27421 gacccagttt atccttgata aaggagtaaa agaaattgat tttggtttga ttctaggttc
    27481 aggattaggt gaattagcag atgaaatcga agatgctgta atgatttctt atgatgagat
    27541 cccgttcttt cctgtttcga cagtagttgg gcatgcagga aagctagttt atgggtctct
    27601 ggcaggcaag aaagtgttag ccatgcaagg gagattccac tactatgaag gtcattccat
    27661 gcaaacagtg acctatccag tacgtgtgat ggccggacta ggggcccatt cagtcattgt
    27721 gactaatgca tgtggtggtg tcaacgaatc atttgtacca ggagatttga tgctgattac
    27781 cgatcatatc aattttactg gtgaaaatcc tttgatcggt ccgaatgaag atgcaatggg
    27841 ccctagattt ccagatatga gtcaagctta tacgcctgac tatcaagcaa cagcaaaagc
    27901 agcagcagaa aaactaggtt tggatcttaa agaaggcgta tatatgggct attctggacc
    27961 aacttatgaa acgcctgcgg agatccgaat gtctcggaca ataggagccg atgcagtagg
    28021 gatgtcgact gttccagaag tcatcgtagc agctcacagc ggattaaaag tgttaggaat
    28081 ctcttgtatt accaacttag cagcaggtat gcaagcgaat ctgagccatg aagaagttgt
    28141 agaaacaact cagagagtca aacaatcttt taaagcattg gttaaagaaa cattgacatt
    28201 attgtaatag gaggaacaat aaaatgagtg tgcatattga agcgaaagaa ggcgagatcg
    28261 ccgataagat tttacttccg ggagatcctt tgcgagctaa atatattgcg gagacttttt
    28321 tggaagatcc agtttgttac aatcaggtac gcggtatgtt aggctttacc ggcaaatata
    28381 aaggagaacg tatttctgtt caaggaacag gaatgggaat gccatcagcc accatctatg
    28441 cccatgaatt gatccagtcg tatggtgtaa agaaattgat tcgagtaggt acatgcggtg
    28501 cattgtcaaa agacgtccat gttcgtgatt tagtactagc acaaggtgca gcgaccagtt
    28561 cttcgatgat cgaaaaaaat ttccaagcct ttcattttcc tccaatcagt gatttcaatc
    28621 tattactgaa agcatatgag atagctaaag aaaagggcta tacggttcat gtaggaaatg
    28681 ttctttcgga agattctttc tacaaagatg atttgacaga gacgttccaa ttagctgaac
    28741 ttggcgtttt aggagtggaa atggaagcag cggctcttta ttacttaggc gcgaaatacc
    28801 atgtgcagac attaagtttg atgaccgtta gcgaccattt gatcaccggt gaagaaacaa
    28861 cagctgcaga acgtcaatct acgttcaatg aaatgatcga agtaggattg gaaacagcga
    28921 tagcagaata agaaggaaat gaaaaagctg ccctgcatta agtaataaga acatccaagc
    28981 aaaaatagct cctcatgttt ttgacttggc tggacttatt attgcaaatg taagcttttg
    29041 aacaccgttt accaagaggt tgtgaatctg ccgtttaact ctgagtcaca aggaacaatt
    29101 tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgaga agttggcagg
    29161 agaaaaccgt ttatacgaaa aaagggactg tgacaaatcg tgtcacagtc ccttttttat
    29221 agtgtttttt ataggtagta ttttttagca actgttaagt catcatttaa ttcataaaca
    29281 agtggttgac ctgttggaat ttcaagatcc atgatgtctt cgtcagagat accttcgata
    29341 tgtttagcta gggcgcgtaa tgagttacca tgtgcagcta ctaaaacagt tttgttgtct
    29401 agtaatgctg gagcaatttc atcttgccag aatggcaaag cgcgttctaa tgtcactttc
    29461 aagttttctc caccaggaat atcgcgtttg tctaacattg cgtaacgacg gtcatttgct
    29521 gcagaacctt cgtcagtttc ttccattaat ggaggaagag tatcgtaaga acgacgccag
    29581 atgtgcactt gttcgtcgcc gtatttttca gctgtttctt ttttgttcaa accttgtaat
    29641 ttaccatagt gacgttcgtt taagcgccat gatttgattt gtggtaccca aagttgatct
    29701 gaatattcta agatcaagtt acatgttttg attgcacgag ttaaaacaga agtgtaagca
    29761 acatcaaatt cgattccagc ttctttgatt ttgcgtccgc cttcttttgc ttcttcgatt
    29821 ccttctggtg ctagatttac atcagcccaa ccagtaaatt ggttcaatgc attccattca
    29881 ctaagaccgt gacgagaaaa aactaatttt ggcatgttta gctctccttt taagataggt
    29941 ttatatttct gaaattttca gttctgtttt attgtacaat tttttggaag agatttccat
    30001 cgaaaaatta gataagattc tatgagaaaa caagtagaga atataaaaaa acgaacagtg
    30061 cccacgcaac tgttcgtttt taggtattag atgcataatt gctcgatttc tttttcaggt
    30121 aaattgatat atttataaca tgttccaact gaaacaccgc attttgaaga aataaattgg
    30181 atcgtttctt ttttttcata atagagacgt cggatttttt tgatcgtttt tgcatcgatt
    30241 tttggtcttc cgccgatttt tcctttttta cgagcttcat ctaatccaac taatgtacgt
    30301 tctttgatca atgcgcactc catgtttgct aggttttcca ttaattggaa atagattttt
    30361 cccatttcgc gcgtatcgat tccttcatca agactaatca agtgcagccc gcgatctttg
    30421 aataattgcg tgagttctgt taattgccgc gtagatttgc ctaatcgatg aagttggcaa
    30481 atgactagtg catcgccttg ttgcatgtca gcgatcactg actccaaatg aacagcagta
    30541 gaatcatttt gttccacttc atatgtctca tggaaaattt cttgacaacc aaagtcagat
    30601 aattgatcaa cctgagttgt taaatcaacg tcatttatgg ttgtgcgtgc ataaccaata
    30661 attttcatgg tgattccttt ctagcagtga ttttctaact ggatataaca gtaaaaatgt
    30721 agcataaagt acgtcaaaaa gatagttttt tcgcaaattt tccgctgtct ttttttattg
    30781 gatgatcaag cagtttttct ttatttacga cggattgcgt caagaatctc aacgcctttt
    30841 tctgagccga caactacttt agaaaccatg tttaggaaaa gcccatgttc tactacccca
    30901 acaagttcat ctaaataggt agctaagctt tctggctgtt cgatgacttc tagatgcaga
    30961 tcaatgatgt aatgaccacc atctgtggtt aagacttctc cgttttcgtc tgtacgcaag
    31021 acgggttgga atcttttttc ttcaaaaata tgaagtagct gttgggagcc ataagggatc
    31081 acttcaactg ggagtgggaa cttcccaagt ttatcgacta atttagaaga atcaacgatc
    31141 caaatcgttt cttttgagta cgtagcgact attttctcga aaagcaaagc agcgccgccg
    31201 cctttgatcc cttgaaaatc agcactgatt tcatcagcac cgtctattgt caaatcgact
    31261 acggggactt catcaatact ctttaacggt attcctaatt tttccgcttg ttcttttgtc
    31321 gcatttgaag tagtaactcc tgtgatacgt aaaccttctt cacgcatacg gcgaccaatc
    31381 tcttctacca tataataggc ggttgaaccg gtcccgagac ctacgatcat cccgtccttt
    31441 acgaatttcg cggcttcaat gccagctaat tgttttaaat tcatctttgc gtccaccttt
    31501 ttttagtttg agcatcgtgc tttcctcact attttagcgt gatttacggt aaaaagatac
    31561 cattcttttt tattccaata aagctttttc aaaaaaaatt gcatctcttg ttgacatgtt
    31621 ttttcattcg tgatattcta acaaaggtgc tttatctaca ggtttctgtg aagaaacgtg
    31681 ctgactgttt atcaaagcat atttgataag gatgcagaca ttgcatttat tttttatcac
    31741 aaaaaaagaa ccacctggat gtgtggaact agacgcaaat cgtgggaagg aggaaacaag
    31801 gaatgcctac aattaaccaa ttagtacgta aacctcgtaa atcaaaggtg gaaaaatcta
    31861 attcacctgc tttgaacaaa ggatataaca gctttaagaa aactcaaact aacgtaaact
    31921 cacctcaaaa acgtggggta gcaactcgtg tgggtacaat gacacctaaa aaaccgaact
    31981 cagctttacg taaatatgca cgtgttcgtt tgtcaaactt aattgaagtt actgcttata
    32041 tcccagggat tggtcataac ttacaagaac acagtgttgt attattacgc ggtggtcgtg
    32101 taaaagactt accaggggta cgttaccata tcgttcgcgg tgctttagat actgctggtg
    32161 ttaacgaccg taaacaaagc cgttctaaat acggaactaa aaaacctaaa gcttaatttt
    32221 aattattaaa caaatgaaac ttgcttctac tatatagaag taattactat gaacaatatt
    32281 tcggaaggag gagttacgga tgccacgtaa aggtcctgtt gcaaaacgtg atgttttacc
    32341 agatcctatt tataactcaa aattagtaac tcgcttgatc aaccgtgtaa tggttgacgg
    32401 aaaacgcggg attgcagcta acattatcta taatgccttt gacttgatca aagaatctac
    32461 aggtaacgat ccattagaag tgtttgaaca agcaatgaaa aacgttcaac ctgttcttga
    32521 agttaaagca cgtcgtgttg ggggttcaaa ctaccaagta ccagttgaag ttcgccctga
    32581 acgccgcgtt actctaggtc ttcgttgggt agtaaactac gctcgcttgc gcggtgaaca
    32641 cacaatggaa gaacgcttag caaaagaaat catggatgct gcaaacaaca caggtgcttc
    32701 tgttaaaaaa cgtgaagaca ctcataaaat ggctgatgcc aaccgtgcgt ttgctcacta
    32761 tcgctggtaa gattctctct gtttggtcgg cttttataag tcgacctcag atagtgtcct
    32821 tatttttagc aactagatag taaagagagg agaaacaagg agaatgacca gagaattttc
    32881 tttacaaaac actcgtaata tcggtatcat ggcccacatc gatgctggta aaacgactgc
    32941 tactgaacgt atcttgtact atactggtaa aatccataaa attggtgaaa ctcatgaagg
    33001 agcttcacaa atggactgga tggaacaaga acaagaacgt ggtattacga tcacttctgc
    33061 tgctactaca gcacaatgga agggtcaccg aatcaacatc atcgacacac caggacacgt
    33121 agacttcaca gttgaagttg aacgttcatt gcgtgtactt gatggtgctg taactgttct
    33181 tgatgcacaa tcaggtgttg aacctcaaac tgaaacagtt tggcgtcaag caacaactta
    33241 tggtgtacct cgtatcgtat ttgcaaacaa aatggacaag atcggtgctg acttcttata
    33301 ttcagtatca actttacatg accgtttgca agcaaacgct cacccaatcc aattaccaat
    33361 tggtgcggaa gacgacttca caggaattat cgaccttgta acaatgaagg ctgaaatgta
    33421 tacaaacgat cttggaacag agatcgaaga aacagaaatt cctgaagaat accgcgaatt
    33481 agctgaagaa tggcgcgaaa aattggttga agctgtagct gaaactgatg aagaacttac
    33541 tttgaaatac ttagaaggtg aagaaatcac tgaagctgag ttaaaagaag gtatccgccg
    33601 cgcaacagtt aacgtagaat tctacccagt actatgtggt tcagcattta agaacaaagg
    33661 ggttcaatta ctattggacg ctgttcttga ttacttgcca tcaccgttag atatcccagc
    33721 tatcaaaggg attgacccta aaactgatga agaagtagaa cgtcctgcag acgacagcgc
    33781 tcctttctca gctttagcat ttaaagttat gactgaccca ttcgtaggtc gtttaacttt
    33841 cttccgtgtg tactctggtg ttttacaatc aggttcatac gtacaaaacg caacaaaagg
    33901 caaacgtgaa cgtgttggtc gtatcctaca gatgcatgcc aactctcgtt cagaaatctc
    33961 tgaagtttac gctggagata tcgctgctgc tgttggtttg aaagacacaa ctactgggga
    34021 cacactatgt gatgaaaaga gtctagttat tcttgaatcc atggaattcc cagaaccagt
    34081 tatccaagtc gctattgaac ctaaatcaaa agctgaccaa gataaaatgg gtgtggcttt
    34141 acaaaaacta tctgaagaag atcctacttt ccgtgctgaa acaaacgtgg aaacaggcga
    34201 aacaatcatc gctggtatgg gtgaacttca cttagatatc atcgttgacc gtatgcgtcg
    34261 tgaattcaaa gttgaagcta acgtaggtgc gcctcaagta tcttaccgtg aaactttccg
    34321 tgctggcact caagccgaag gtaagtttgt acgtcagtct ggtggtaaag gtcaatacgg
    34381 tcacgtatgg attgaattta caccaaatga agaaggtgct ggtttcgaat ttgaaaatgc
    34441 gatcgtcggt ggggttgttc ctcgtgaata cattccagct gttgaaactg gtttgaaaga
    34501 tgctatggaa aatggtgtct tagctggcta tccattagta gatatcaaag ctaaacttta
    34561 cgatggttca taccatgatg tcgattcaaa tgaaactgcc ttccgtgttg ctgcttctat
    34621 ggcattacgt gcagcagcta agaaagctaa tccagtaatc cttgaaccaa tcatggctgt
    34681 agaagttgtt atccctgaag attatttagg tgatgttatg ggtcacgtaa ctgctcgtcg
    34741 tggacgtgtt gaaggtatgg aagctcgcgc tggcggccaa caagttgttc gtgcgatggt
    34801 tccacttgct gaaatgtttg gttatgctac aactcttcgt tctgctactc aaggtcgtgg
    34861 tacatttaca atgacatttg accactacga agatgtacca aaatcagtac aagaagaaat
    34921 cattaagaaa aacggcggaa aagctgaata atttcttgaa accggatagt cctgcaaaga
    34981 gattatccaa agagactata tttttaatat agtttcgtgt aaaataatta tcgatgatat
    35041 gggcatgtgg tgtaccttgt gtacatcata tacctatcag acaaataaaa aatatattgt
    35101 atttttagga ggacatttta aaatggcaaa agaaaaattt gaccgttcta aaccacacgt
    35161 taacattggt actatcggac acgttgacca tggtaaaact acattaacag ctgcaatcac
    35221 aactgtacta tctaagaaaa acggcggcca agctatggct tacgatcaaa tcgatggtgc
    35281 tccagaagaa cgcgaacgcg gaatcacaat ctcaacagct cacgttgagt atgaaacaga
    35341 tacacgccac tacgctcacg ttgactgccc aggacacgcg gattacgtta aaaacatgat
    35401 cactggtgct gctcaaatgg acggagctat cttggtagtt tctgctgctg acggcccaat
    35461 gcctcaaact cgtgaacaca tcctattgtc tcgtcaagtt ggtgttcctt acatcgttgt
    35521 attcttgaac aaagtagaca tggttgatga cgaagaatta ctagaattag ttgaaatgga
    35581 agttcgtgac ctattaacag aatacgaatt ccctggtgac gatgttcctg tagttgctgg
    35641 atcagctttg aaagctctag aaggcgacgc ttcatacgaa gaaaaaattc ttgaattaat
    35701 ggctgcagtt gacgaataca tcccaactcc agaacgtgac aacgacaaac cattcatgat
    35761 gccagttgaa gacgtgttct caattactgg acgtggtact gttgctacag gtcgtgttga
    35821 acgtggacaa gttcgcgttg gtgacgaagt tgaagttgtt ggtattgctg aagaaacttc
    35881 aaaaacaaca gttactggtg ttgaaatgtt ccgtaaattg ttagactacg ctgaagctgg
    35941 agacaacatt ggtgctttac tacgtggtgt tgcacgtgaa gacatccaac gtggacaagt
    36001 tttagctaaa ccaggtacaa tcacacctca tacaaaattc tctgcagaag tatacgtgtt
    36061 gacaaaagaa gaaggtggac gtcatactcc attcttcact aactaccgtc cacaattcta
    36121 cttccgtaca actgacgtaa caggtgttgt tgaattacca gaaggaactg aaatggttat
    36181 gcctggcgac aacgtaacaa tggaagttga attaatccac ccaatcgcta tcgaaaacgg
    36241 tactaaattc tcaatccgtg aaggcggacg tacagttggt gccggtgtcg ttacagaaat
    36301 caaagcttaa ttcacttaag ttttaaagta aagcaacatt tattcggacg taatcgctcg
    36361 gaacgaaggt cttaggatct ttgttccgag cttttttatt tattgcagga tcaggaaaaa
    36421 agacaggagt attataaata gaagaaacac gaaataaaag agtcagtatt ttctaaatga
    36481 aactttatga aaacaaaatg ttttttacaa gaaaaagcct tgctttgtga gtttatatat
    36541 attataatga caaaggtgcg tttactttag tgaattgcac agacgtaatc agaatgattt
    36601 cgtcggctaa gaaacgagag gttgcgacac gcccggacgc tttgccacga acgagcgtga
    36661 cggaaatttt cgtggagcta tgtctacttt tcaaaatagg cgaaggaggg aacaagatgg
    36721 caaaacaaaa aattcgtatc cgtttaaaag cgtatgaaca ccgtatttta gatcaatcag
    36781 cggataaaat cgtggaaact gcaaaaagaa ctggagctag cgtgtctggt ccaattccat
    36841 taccaactga acgcagtctt tacacaatca tccgtgcgac tcataaatac aaagattcac
    36901 gcgaacaatt cgaaatgcgt acacacaaac gtcttatcga cattgtgaac ccaacaccaa
    36961 aaactgttga tgctttgatg aagctagact taccatctgg tgtaaacatc gaaatcaaat
    37021 tataaaacta aaacaaaaat aatggaggtg tactcatgac caaaggaatc ttagggaaaa
    37081 aagtgggaat gacacaaatc ttcactgaat ctggtgaatt aattccagta actgttgtag
    37141 aagctactcc aaacgtagta ctacaagtga aaacaatgga aacggatggc tacgaagcta
    37201 ttcaagttgg ttaccaagat atgcgtgaag ttttatcaaa caaacctgcg aaaggtcatg
    37261 ttgcaaaagc aaacacggct cctaagcgct tcattcgtga attcaaaaat gttgagctag
    37321 gagaatatga agtaggaaaa gaaattacag tagatgtttt ccaagcagga gacattattg
    37381 atgtaacagg tactacgaaa ggtaaaggat tccaaggggt tatcaaacgc cacggacaaa
    37441 gccgcggacc aatggctcac ggttctcgtt accatcgtcg tcctgggtca atgggtccag
    37501 ttgcacctaa ccgtgtattt aaaaacaaac gtcttgctgg ccgtatgggt ggcaaccgcg
    37561 taactatcca aaacttggaa gttgtacgtg tcgatgcaga aagaaatgtt atcttgatca
    37621 aaggtaatgt tcctggagct aaaaaatctt taattactat caaatcagct gtgaaagcta
    37681 aataattgta ggaagaaagg aggaactaag gaatgccgaa tgtagcatta ttcaaacaag
    37741 atggaagcca aaacggtgaa atcacactta acgaagaaat cttcggaatt gaacctaatg
    37801 aaagtgttgt ttacgatgca atcgtaatgc aacgtgcgtc attaagacaa ggaacacacg
    37861 cggttaaaaa ccgtagcgct gttcgcggcg gcggacgtaa accatggcgt caaaaaggaa
    37921 caggtcgtgc acgtcaagga tctatccgct caccacaatg gcgtggaggt ggcgtagtct
    37981 ttggaccaac accacgttct tacagctaca aacttcctaa aaaagttcgt cgtttagcaa
    38041 tgaaatctgt attgtcagaa aaagttgctg aaaacaactt ggtagcaatc gaaggcttga
    38101 acttcgacgc accaaaaaca aaagaattca aacaagttct tgctaactta tctatcgact
    38161 ctaaagtatt ggttgttcta gaaaaaggta acgactttgc tgctttatca gcacgtaact
    38221 taccaaacgt ttctgtagta acttctgata atgtgagtgt gctagacgtt gtatcaaata
    38281 caaaagtgtt agcaacacaa actgctctta ctcaaattga ggaggtgctt gcataatgaa
    38341 cttactagac gtaatcaaac gcccagtgat cactgaaaaa tcaatgcttg ccatggatga
    38401 caagaaatac acttttgaag tggacactcg cgcaaacaaa actttagtaa aacaagcggt
    38461 agaagctgct tttgacgtta aagtcaaaaa cgtgaacatc gtgaacgtac gtgcgaaatt
    38521 caaacgtatg ggcaaatatg caggatatac aaaaaaacgt cgcaaagcga tcgttacatt
    38581 gactgaagat tcaaaagaaa tccaattatt cgaagctgct gaataagcac taatagataa
    38641 ctcattaaat taggagggaa aaacgtggcg attaaaaagt acaaacctac ctcaaatggt
    38701 cgtcgtaaca tgacaggttc tgattttgct gaaatcacaa catcaacacc tgaaaaatca
    38761 ttgttacaac cattgaaaaa ccatgctgga cgtaacaaca acggccgcat cactgtacgt
    38821 catcaaggtg gcggacacaa acgccaatat cgcgtgatcg acttcaaacg taacaaagat
    38881 aacgttgttg caactgttca aacgatcgaa tatgatccaa accgttcagc taacatcgcg
    38941 ttagtacact atgaagatgg agtgaaagct tacatcttag cacctaaagg actagaagtg
    39001 ggtatgaaac ttgtttcagg tccagaagca gatatcaaag tcggaaatgc tcttccatta
    39061 gaaaacattc cagttggtac tgttatccac aacattgaaa tgaaacctgg taaaggtgga
    39121 caattgatcc gttctgctgg tacaagtgct caagtacttg gtaaagaagg caaatacgta
    39181 ttgatccgct tgaactctgg tgaagttcgt atgatcttag ctgcatgccg tgctacaatc
    39241 ggttctgtag gtaacgaaca acacgaatta atcaacatcg gtaaagctgg acgctctcgt
    39301 tggatgcgta aacgcccaac tgtacgtggt agcgtaatga accctaatga tcacccacac
    39361 ggtggtggtg aaggtaaagc tcctatcgga cgtaaagcac cagtttctcc ttggggtcaa
    39421 ccagctcttg gttacaaaac tcgtaacaaa aaagctaaat cagacaaact tattgttcgt
    39481 cgtcgcaaaa ataaataatt actttgacca tgtgtcgcac attttgagag gaggttcacc
    39541 atgggtcgta gtttaaagaa aggacctttt gtcgatgagc atttaatgaa aaaagttgaa
    39601 gctcaagcag gggttgaaaa gaaaaaagtt atcaaaactt ggtcacgccg ttcaacagtt
    39661 ttcccaagtt ttgttggata taccatcgca gtttatgatg gacgtaaaca tgtaccagtt
    39721 tacatccaag aagacatggt aggacacaaa ttaggtgaat ttgcacctac aagaacttat
    39781 cgtggacatg ctgctgacga taagaaaacg aaacgctaat ttgaggggag gataaatcca
    39841 aatggcagaa caaatcacat cagctaaagc aactgcaaaa acagttcgca cttcacctcg
    39901 aaaagcccgt ttagtaattg accttatcag aggtaaaagt gtcgcagatg caatttcaat
    39961 cttgaaattc acaccaaaca aatctgctgg aatcattgaa aaagtattga tgtcagcagt
    40021 tgcgaatgca gaaaataact ttgacttaga tgttgaaaac ttggtagtaa gcgaagcttt
    40081 tgttaacgaa ggacctacaa tgaaacgttt ccgtcctcgt gcaaaaggat cagcttctcc
    40141 aatcaacaaa cgtacaagtc atatcacggt agtcgtatca gaaaaataag gagggataat
    40201 cagtgggtca aaaagtacat ccaattggaa tgcgtgtagg catcatccgc gactgggatg
    40261 ctaaatggta tgctgaaaaa gagtatgctg agttcttaca cgaagattta agaatccgta
    40321 aatttatttc aactaaactt gctgatgctg ctgtatcaac agttgaaatc gaacgcgcaa
    40381 caggtcgcgt aaacatttca attcacacag ctaaaccagg tatggttatt ggtaaaggcg
    40441 gttctgaagt cgaaagccta agaaaagaat taaacaaatt aactggtaaa agaatccata
    40501 tcaatatcgt ggaaatcaaa aaaccagatc tagatgcaaa attagtaggt gaaggaatcg
    40561 cacgtcaatt agaaaaccgt gttgctttcc gtcgcgctca aaaacaagcc atccaacgct
    40621 caatgcgtgc tggcgctcaa gggatcaaaa ctcaagtatc tggtcgtcta aacggagcag
    40681 atatcgctcg ttcagaagga tactcagaag gaactgttcc tcttcatact ttacgtgcgg
    40741 acattgatta cgcatgggaa gaagcagata caacatacgg aaaactagga gttaaagtgt
    40801 ggatctatcg tggagaaatt cttccaacta aaaaaaacac tgagaaagga gggaaataat
    40861 catgttagta cctaaacgtg taaaacaccg tcgtgaattc cgcggaaaaa tgcgcgggga
    40921 agctaaaggc ggaaaagaag tagcattcgg tgaatacggt ttgcaagctg ttgattcaca
    40981 ttggatcaca aaccgccaaa tcgaagctgc tcgtatcgca atgactcgtt acatgaaacg
    41041 tggtgggaaa gtatggatta aaattttccc tcacaaatct tatactgcca aagcaattgg
    41101 ggtacgtatg ggttctggta aaggggcacc tgaaggatgg gttgcaccag taaaacgtgg
    41161 taaaatcatg tttgaaatcg caggcgttcc tgaagaagta gctcgtgaag cgttacgtct
    41221 agcttctcac aaattaccaa tgaaaactaa gatcgtaaaa cgtgaggaaa tgggtggtga
    41281 atcgaatgaa ggttaaagaa atcagagaat taaccactgc cgaaatgctt gatcaagaaa
    41341 aacaattaaa agaagaattg tttaatctta gattccaatt agcaacaggt caattagaaa
    41401 acactgcacg tattaaagaa gtacgtaaat cgattgcacg catcaaaact gtgttgcgtg
    41461 aacaagctaa gtaattatgg aaggaggcca ttaagcgtat gactgaagga agaaatcaac
    41521 gcaaagttta tcaaggtcgc gtggtttcag acaaaatgga taaaacaatt accgttgctg
    41581 tcgaaacaaa gaaaaaccac cctatctatg gcaaacgcat gaactattct aagaaataca
    41641 aagtgcatga tgaaaacaac acagcaaaag ttggcgacat cgtgagaatt atggaaactc
    41701 gtccattatc agctacaaaa cgtttccgtt tgttggaagt agtcgaagaa gcagttatta
    41761 tctaataaca cgagattttc ctatatagat tgaatgcaaa atctgaaagg aggatacaca
    41821 acgtgatcca agcagaaagt cgtttaaaag tcgctgataa ctcaggcgca cgtgaaattt
    41881 tgacgatcaa agtccttggt ggatctggtc gtaaaactgc taacatcggt gatgtgatcg
    41941 ttgctacggt taaacaagca acgccaggtg gggttgtcaa aaaaggtgac gtcgttaaag
    42001 ccgttatcgt tcgaacaaaa tcaggagctc gtcgtacaga cggttcatat attaaatttg
    42061 atgaaaatgc tgcagtgatt attcgtgatg ataaaagccc tcgtggaaca cgtatctttg
    42121 ggccagttgc acgtgaacta cgtgaaaaca acttcatgaa gatcgtttca ctagcaccag
    42181 aagttttata atcttgagac acttatcaaa ggaggtgcga aacagttatg tttgttaaaa
    42241 aaggcgataa agttaaagtt atcactggaa aagacaaaaa caaagaaggc gttgtactag
    42301 cagcgttccc gaaaaaagat aaagttattg tcgaaggtgt aaatgtcgtt aaaaaacacc
    42361 aaaaaccttc tcaagctgct cctcaaggtg gaattgttga gatggaagcg ccaattcatg
    42421 tttctaacgt gatggtggtt gactctactg gtgtagctgg ccgagttggc tacaaagaag
    42481 tagacggcaa aaaagtccgt gtttctaaaa aaaccggtga agttttagat aaataaaagt
    42541 ttaaggaagg agggtcttac tgaatgaacc gcctaaaaga aaaatatctt aaagaagtaa
    42601 ctccatcatt gatggaaaaa tttaactata gctctgttat gcaaacacct aaagttgaaa
    42661 aaatcgtcat caacatgggt gttggtgatg cggtatcaaa cgctaaaaac ttagataaag
    42721 cagttgaaga attaactttg atcactggtc aaaaaccaat gattacaaaa gctaaaaaat
    42781 caatcgctgg attccgttta cgtgaaggaa tgccaattgg tgcaaaagtt acattgcgcg
    42841 gagaaagaat gtacgaattc ttagacaaat tggtttctgt ttcactacca cgtgtacgtg
    42901 acttccatgg tgtaagtaaa aaagcctttg acggtcgtgg aaactatact ttaggtatta
    42961 aagaacaatt gatcttccca gaagtagatt atgatttagt agataaagta cgtggtatgg
    43021 acatcgttat tgtaacaaca gcaaactctg atgaagaatc tcgtgagttg ttgacacaat
    43081 taggcatgcc attccaaaaa taattaaagg aggcgaacta cgtggctaaa aaatcaatga
    43141 ttgctaaaaa caaacgtcct gcaaaatttt caacacaagc ttatactcgt tgcgaacgtt
    43201 gcggacgtcc acattcagtt tatcgtaagt tccatctttg ccgtatttgc ttccgcgaac
    43261 ttgcctataa aggtcaaatt cccggcgtga agaaagctag ctggtaaaaa gtaaattcgc
    43321 ataagaagga ggtaaaagat caatggtcat gacagatcca attgcagatt ttctaactcg
    43381 tatccgtaac gcaaacatgg ttaaacatga gtctttagaa gtacctgcat caaaaattaa
    43441 acgtgacatc gctgaaatct tgaaacgtga aggtttcgtt cgtgatgttg aatacatcga
    43501 agatgacaaa caaggcgtga tccgtgtttt cctaaaattt ggtaaaaacg gcgaacgtgt
    43561 tatcacaaac ttaaaacgta tctctaaacc aggtttgcgt gcttatgtca aagctgacga
    43621 agtaccaaaa gtattgaacg gtttaggtat cgcaatcatt tcgacttctg aaggtgttgt
    43681 cactgataaa gaagctcgtg aaaaaaatat cggcggcgaa gttatcgctt acgtatggta
    43741 atcaagtaga atctacaagg aggtgtcttt aagtgagccg tatcggaaat aaagtcgttg
    43801 ttatccctga aggagtaaca gttactcaag acggaaacaa cgttacagtt aaaggaccaa
    43861 aaggtgaatt gactcgtact ttttcagcag atatcaaaat gaatatcgaa ggaaacgaag
    43921 taactttcac tcgtccaaac gacagtaaag aaatgaaaac aattcatgga acaactcgtg
    43981 cgaacttcaa caacatggtt gtaggtgtca gcgaaggttt ccaaaaagcg ttagaactaa
    44041 tcggggttgg gtaccgtgca caattacaag gatcaaaact tgtattgaac gttggttact
    44101 cacatccagt agaaatcaca ccaccagctg gagtaactgt tgaagtacca gctaacacac
    44161 aagtaattgt taaaggtgcg aacaaagaag aagttggcga attagctgca aacattcgtg
    44221 gaactcgtcc tccagaacct tataaaggta aaggtattcg ttatgttggc gaatatgtac
    44281 gccgtaaaga aggtaaaact ggtaaataat cgtttagaaa aattgcatag aagccagcag
    44341 caggaaaaag gcatttggct gaagtttacc ttcaaaaaaa tacattttta cttgtgccgc
    44401 agcttctatt tttcgaaacg tatttactgc ttgaaatagt agtacaataa aaataaagag
    44461 gtgacaattg tgattacaaa accagataag aacaaaacac gtcaaaagag acatcgtcgt
    44521 gtacgtaaca atatctctgg tactgctgag cgcccacgct tgaacgtttt tcgttctaac
    44581 aaaaacatct acgctcaaat tattgatgac gtagcgggtg taacgctagc aagtgcctct
    44641 accttggata aagaaatttc aggtggaaca aaaacagaag cagcacaagc tgtcggtaaa
    44701 ctagttgctg aacgtgcagc tgaaaaaggc attaaagtag tagtctttga ccgtggtgga
    44761 tacctttacc atggccgtgt gcaagcttta gctgaagctg ctcgcgaaaa tggactagaa
    44821 ttttagaaga aggaggaata ccattcatgg tttatatcga tccaaaacat ttggaattag
    44881 aagaccgcgt tgttgcaatt aaccgtgtaa caaaagttgt taaaggtgga cgtcgtctac
    44941 gttttgctgc tttagttgtt gtcggtgaca aaaacggaca cgtagggttt ggtacaggta
    45001 aagctcaaga agttcctgaa gcaatccgta aagcaattga agatgcgaag aaaaacttag
    45061 ttgaagtacc tatggttggt tcaacaatcc cacacgaagt aatcggtgct tttagtggtg
    45121 gtagaatcct aatgaaacct gctgtagaag gttctggggt tgctgctggt ggaccagttc
    45181 gtgccgtatt agaattagct ggggtagcag atatcacttc taaatcttta ggctcaaata
    45241 caccaatcaa cgttgttcgc gcaacagttg aaggtttgaa acaattgaaa cgtgcagaag
    45301 aagttgcaga acttcgcggc aaatcagttg aagaattaat cggataagga ggacaacaat
    45361 aatggctgaa ttaaaagtta ctttaaaacg cagtattatc ggacgtcctc aaaaccaacg
    45421 cgatacagtt aaagcgttag gtcttacaaa gattaacagt tcagtggtta agccttctaa
    45481 tgaagcaatt aaaggcatga tcaatactgt ttctcaccta gtggacgttg aagaaattta
    45541 atttagaaaa atcataacta gaacattaag gaggtgccaa acctatgaaa cttcatgaat
    45601 taaaacctgc tgaaggttca cgccaagtac gtaaccgtgt tggtcgtggt acttcatctg
    45661 gtaacggaaa aactgccgga cgcggacaaa aaggacaaaa agctcgttca ggcggcggtg
    45721 tgcgtttagg atttgaaggg ggacaaacac cattgttccg tcgtttacca aaacgaggat
    45781 tcacaaacgt gaaccgtaaa gactatgcag tcattaatct tgatgtattg aaccgctttg
    45841 aagacggagc tgaagtaact cctgttgctt tagttgaagc tggaatcgtg aaaaacgaaa
    45901 aagctggaat caaagtatta gctaatgggg aactaaacaa gaaattaact gtgaaagcag
    45961 caaaattctc taaagcagct caagaagcaa ttgaagcggc tggtggatca atcgaggtga
    46021 tctaatgttt agactattaa aagatgcttt taaagtaaaa gacattagat cgaaaatcct
    46081 atttactgta tttgtgttgt ttgtatttcg cctaggtgca catattactg taccaggcgt
    46141 aaatgctgct tcattgcaaa acctttcttc tttgccattt ttcaacatgt tgaacttggt
    46201 aagtggtagt gcgatgcaaa acttttccat tttctcaatg ggggtttcac catacattac
    46261 tgcttctatc gtcattcagc ttcttcaaat ggacatcgtg cctcgatttg ttgaatggtc
    46321 gaaacaaggg gaagttggtc gtaaaaaact gaatcaagcg actcgatatc tgacattagt
    46381 attggcattt atccaatctg tcggtatcac tgctggattc aatcaatacg ctcaattagg
    46441 tttcgtgaat aatcctaacg tagcaactta cgtaacgatc ggtttgattc taacagccgg
    46501 tacgatgttt gttacttggc taggagaaca gatcacagaa aaaggtatcg gaaatggcgt
    46561 atcaatgatc atttttgcag gtatcatttc tagattgcct gaaagtatca gagaaattta
    46621 tgaagattac tttataaata ttgatccttc agacatatgg aaatctgcta tttttgtggc
    46681 cattttacta gtagcggtct tgttgatcgt gacattcgta acatttttcc aacaagctga
    46741 acgcaagatc ccgatccaat atacgaaacg cgtagctggc gcgcctacaa gcagctatct
    46801 gccgttgaaa gtaaatgcag ctggagttat tccagttatc tttgctagtt cgtttattgc
    46861 tacgccaaat gctgttttac aagcattgag cggtagattc ggttctgaaa actggtacaa
    46921 agtgatgatg gagatcttta actataatac agcacctggt gctacgattt atacgattct
    46981 gatcgttgcc ttcactttct tctacgcctt tgttcaagta aaccctgaga aattagcgga
    47041 aaacttgcaa aagcaaggaa gttatatacc aagcgtacgc cctggtaagg ggactgaaga
    47101 gtatgtctca agattactga tgcgtttaag tacagttggt gcagtcttcc ttggtttagt
    47161 ggcattgctt ccaatcattg ctcaaatggt ttgggatctt ccacaatcaa tcggattagg
    47221 cggtacaagc ttactgatcg ttatcggtgt agctttagaa actgcgaaac agttagaagg
    47281 cttaatgctg aaacgtaaat atgttggatt cattgagtaa gaaagcgtgt tgaggtttcc
    47341 cctcaacaca cgttctcaca catttattag gagggaaaac aatgaacctc attttaatgg
    47401 ggctgccagg cgcaggtaaa ggaacacaag ctgaaaaaat cattgatgct tatggtattc
    47461 cgcacatctc aacaggagat atgttccgcg cagcgatgca aaacgaaaca gctcttggcc
    47521 tggaagcaaa gtcttatatg gataaaggtg cattagttcc tgatgaagta acaaatggaa
    47581 tcgtgaaaga gcgactagct gaaccagata cagagaaagg cttcttatta gatggctttc
    47641 cacgtacgct agatcaagca aaagctctgg acgcaatgct aaaagatttg aataaaaaaa
    47701 ttgatgctgt catcgatatc catgttggtg aagaaatctt ggtcgaacgt ctagccggcc
    47761 gatttatctg cagcaattgt ggagcaactt accataaaat tttcaaccct acaaaagttg
    47821 aagacacatg tgatcgttgc ggtgggcatg aattctatca aagagaagat gataaacctg
    47881 agacggttaa aaatcgtctg gctatcaaca tcaaaaatag tgaaccaatc ttggcttatt
    47941 ataaagaaca aggtttgcta aacactattg atggtgctcg tgaaatcgat gctgtatttg
    48001 cagatgtaca aaaaatcatt gaaaaatagc acgattgccc gtagccgact tgcattatgc
    48061 agttactctt gtcaagttca ataaattatg atagaatatg tcagtccgac ttctagagaa
    48121 tcctctagat gatccatttt gagaattttg aggtgggaac tgcagtttcc gccattttat
    48181 cgtgtgaaaa tgcgaaacaa gtacaaggag gtactgtgcg tggcaaaaga agatatgatt
    48241 gaagtcgaag gtacagtcgt cgaaactttg ccgaatgcaa tgtttaaagt tgaactagaa
    48301 aacggacacc aagttcttgc tactgtttca ggtaaaattc gtatgcatta catccgtatc
    48361 ttacctggtg acaaagtaac ggttgaattg tctccatacg atcttaaccg tggccgtatt
    48421 acttatcgct ttaaataatt gtactccgta aaactacagg aggtattatc atgaaagtaa
    48481 gaccatcagt aaaaccaatg tgcgaacatt gtaaagtaat tcgtcgtaaa ggacgcgtta
    48541 tggtgatttg cccagcaaat ccaaaacata aacaacgtca aggataattg gaggtgctat
    48601 aaatatggct cgtattgcag gagtagatat tcctcgtgat aaacgtgtag tagtttcact
    48661 tacttatatc tatggtattg gtaacactac tgctaaaaag atcttagctg atgctggtgt
    48721 atctgaagat gttcgcgttc gtgaattaac gaatgaacaa acagatgcta tccgtgcaga
    48781 agtagataaa ttaaaagttg aaggggatct tcgtcgtgaa gtgaacttga acatcaaacg
    48841 tttgatggaa atcggttctt accgtggaat ccgtcatcgc cgtggattgc ctgttcgtgg
    48901 acaaaacacg aaaaacaatg cacgtactcg taaaggccca gctcgcgcta tcgctggcaa
    48961 gaaaaaataa ttcttaagtg aaggaggtta aaacttcatg gcagcaaaaa aagtgaatcg
    49021 taaacgccgt gtgaagaaga atatagaagc aggtattgca catatccatt ctacattcaa
    49081 taacactatc atcatgatca ctgatactca cggaaatgca ttagcgtggt catcagctgg
    49141 ttcattaggt ttcaaaggaa gcaaaaaatc aactcctttt gccgctcaaa tggcagcaga
    49201 aactgctaca aaagcagcaa tggaacacgg attaaagact gttgaagtaa cagttaaagg
    49261 acctggttct ggacgtgaag cagcaattcg ttcattacaa gctacaggtt tagaagtgac
    49321 tgcaattcgt gacgtgactc cagttcctca taatggtgcc cgccctccaa aacgccgtcg
    49381 tgtttaatga gtgccgctca ttttgagttt tatcagtaac gtcattgaac aagacacttt
    49441 tcgttttgaa aggggtaaag ataagaatga ttgagttcga aaaaccaaga atcgcaaaaa
    49501 ttgatgaaga aaaagattat ggcaagttca tcgttgaacc tcttgaaaga gggtatggga
    49561 ctactttagg gaattcccta cgtcgtattt tattatcttc tttgccaggt gctgccatca
    49621 ctaatattca aatcgatggt gtactgcatg aattctctac catcaaaggt gttagagaag
    49681 acgtcactca aatcatcttg aacattaaag gcttagcgct gaaaatgtat ggccaagaag
    49741 aaaaaaccct tgaaatcgat attaccggac ctgctacagt aactgctggc gatattatcg
    49801 ttgatagtga tgtagaaatt cttaacaaag atatgtacat ctgtagtgtc tctgaaggag
    49861 ctacgttcca tgctcgctta acagtgaaac ctggacgtgg ttatgttcaa gcagatgaaa
    49921 ataaaaaaga agatatgcca attggcgttc ttccagtcga ttcaatctac acacctgttc
    49981 gtcgtgtgaa ctatcaagtt gagaacacac gtgttggaca ccgtgaagat tttgataaat
    50041 tgacgatgga gatttggaca gatggttcaa ttgaaccgtt ggaagcaatg agtttgtctg
    50101 cgaaaatcat gactgaacat ttggatattt ttgtgaactt aactgatgaa gcaaaaaatg
    50161 ctgaaatcat ggtcgaaaaa gaagaaacac aaaaagaaaa aatgttggaa atgacgatcg
    50221 aagagttaga cttgtctgtt cgctcttaca attgtttgaa acgtgcagga atcaatactg
    50281 tacaagaact tacaaataaa tctgagcctg aaatgatcaa agtccgtaac ttaggacgta
    50341 aatcattaga agaagttaaa gcaaaattgc acgacttagg tttaggttta cgtaaagaag
    50401 attaaaacct tttacgaagg agggaaacca acgtgagtta tcgtaaacta ggacgcacat
    50461 ctagccaacg taaagcgatg ttgcgtgatt taacaactga tttattaatc aacgaacgta
    50521 ttgtgactac tgaagctcgt gcgaaagaag ttcgctcaac tgcagaaaaa atgatcactt
    50581 taggtaaacg cggagatttg catgcacgtc gtcaagctgc ggctttcgta cgtaatgaag
    50641 ttgccagcgt gcgtgaagaa aatgaggaca tcgtcattga atcagcttta caaaaactgt
    50701 tcaacgatat tgcacctcgt tacgcagaac gtcaaggcgg atacacacgc attttgaaga
    50761 cagaaccaag acgcggtgat ggtgcaccaa tggttgtctt agaacttgtc taaaatcaca
    50821 ctaataacat cactttatag atgattcttt tagagtgtta tgatgttgga agatattttt
    50881 ccgagtctag ctcagcgctg ctcctcaagc gaatatcgct tggggagtaa gcactcatca
    50941 taaagtgttt ttttatacct tcaattacct gtcatgacag atatgtttga aggcataaaa
    51001 aaacatttta agcgagaaat aattgaaaat tttgtctttt tttgatagtg ttagtaggaa
    51061 ctttaggatg aagaaggagt aatcatggag ccaattattg aattagaaaa gataaattat
    51121 aaataccagc cagatgatct tcgccccgca ttgaaagatg tctcctttac aattgataaa
    51181 ggtgagtgga tcgctattat tggacacaat ggttcaggaa aatcgacact tgccaaaacg
    51241 atcaatggat tgcttctgcc agaatcaggg atcgtgaaag tgggaaatca aatattggat
    51301 gaagaaaata tttggacgat ccgacagatg gttggaatgg tttttcaaaa tccagacaat
    51361 cagtttgttg gttcgacagt agaagatgac gttgcttttg gtcttgaaaa tcaagggatt
    51421 cccagagaag aaatgctagt gcgtgtgaaa gatgcacttg agaaagttag aatggctgag
    51481 tttgcttcac gcgagcctgc tcgtttatca ggagggcaaa aacaacgtgt tgccattgcc
    51541 ggcgtggttg ccttacgacc tgatatcatt attttagatg aagcaaccag tatgctagat
    51601 ccagaaggtc gtgaagaagt gatctctacg atcaagaaga tcaaagaaga aagtcaattg
    51661 accgttatat ctatcactca tgatattgat gaagcagcta atgccaatcg gatactagtg
    51721 atgagacaag gcgaacttgt ccgtgaaggt acaccaaaag aaattttttc tgctggtcct
    51781 gaactgatcg acttaggtct agatctacca tttcctgaaa aactgaagag cgcactgaaa
    51841 gaacgtgggg ttgatgtgcc cagtgaatat atgacagaag aaaggatggt ggattggtta
    51901 tggacatccg ttttgaacaa gtagacttca cttatcagcc gaatacacca tttgaacaaa
    51961 gagccttatt tgacatcaat atgacgatca aagaaaacag ttatactgca ttagtagggc
    52021 ataccggaag cgggaaatca accttacttc agcatttgaa tgcgcttgtt aagccaacaa
    52081 gcggtacagt ccatattgga gaacgagata ttcagccgga tacggataat aagaatttaa
    52141 agcccatccg aaaaaaagtt ggcatcgtct ttcagtttcc agaagcacag ctattcgaag
    52201 aaacggtagc aaaagacatt gctttcggtc ctaaaaactt tggtgtcagc gaagaagaag
    52261 cactagtcct agcaaaagaa acattagaac aagttgggct ggatgaaagc tatttggaac
    52321 gttcgccatt tgaactttca ggagggcaaa tgcgtagagt agcaatcgct ggtgtgcttg
    52381 ccatgaggcc ggaagtactt gtattggatg aaccaacggc aggacttgat ccccagggta
    52441 gaaaagaaat gatggagatg ttttggcgtc ttcataagga acagcagatc actattgtat
    52501 tagttacgca tttaatggat gatgtagcca attttgcaga ttatgtctat gtgttggaaa
    52561 agggacgaat cgttaatagc ggggagccgc aagaggtctt tcaaaacatt gaatggctaa
    52621 aagaaaaaca actaggcgta cctactgcca ccgagtttgc agaagaatta atggctaaag
    52681 ggatgaactt tgctaccttg cctttgacag ctgaagaatt agcagacgct atcgtccatt
    52741 atgctggagg aaatgcccat gatgaataaa ttgatatttg gtcgttatat gcctggagat
    52801 tccttgatcc atcgattgga tccccgagct aaattattag ccagttttta ttttatcgga
    52861 atcatttttt tagcaaataa ttgggaaacg taccttttgt tggcattttt cacattactt
    52921 tctgtcttct tgtcaaaagt agatttgaaa ttttttatcc gaggcattcg cccattgatc
    52981 tggctaatcc tcttcactgt agctttgcag gtcttgttta caagtggcgg agaaacttat
    53041 tggagttggg gtgttttcca tatcactgaa tttggtgtga tgaacggcct ctttattttc
    53101 tgtcgattcg tgttgatcat ttttatgtcg actctactca cgcttactac accgcctttg
    53161 gaattatcgg atgcgattga gtacttgctt cgtccattga aagccgtacg gttcccagtc
    53221 cacgaaattt cattgatgct gtcgattgct cttcgttttg tgcctacatt gatggacgaa
    53281 acagaaaaga tcatgaacgc tcagcgcgct cgcggtgttg attttggtga aggaaaccta
    53341 gttcagaaaa tgaaagcagt cattcctttg ctgattcctt tatttgtcag cagcttcaac
    53401 cgtgcggaag atcttgcgac tgctatggaa gcaagaggct acaaaggtgg ggaaggaaga
    53461 acgaaatatc gtgtattgca ttggcataat agagacacga tggttatcat tgcttttgta
    53521 ttattaactg tgctactgat ctttttgaga ggataaacgt tcagtgggcc gctatctatt
    53581 cttttcttgc tgatctgttt gcaagaaagg atgcgagcag tgtatgacaa gaaatattag
    53641 ggtctgtggc agactaaggt cacaggcctc tttcttttat ctgaaaagaa agaacgaaaa
    53701 aattttataa aaaaatcatt attccagata accttttagg aacaaaggag agaaaaacat
    53761 ggtacgttac aaagcaatca ttgcatacga cggaacaaat tttaatggat tccaaaaaca
    53821 gccaaatggg cgtactgttc aagaagaagt agaaaaaaca ttacaaaaaa tggcaaatgg
    53881 aaaagaaatc acggtctttg gttcgggaag gacagatgcc ggagtacatg cgattgggca
    53941 agtaatccat tttgattatc cagaggagcg tccgttagaa cgaatgcgtt tcgcgctaga
    54001 tacccagtca ccagaggata ttgctgtaag acaagtagaa attgtttcag aagacttcca
    54061 cgcaagatat ttggtcaaag aaaagacgta tcaatttcga gtggatatag ggaaaccacg
    54121 cagtcctttt cgacgccatt atgcaagtta ttttccttac cctcttgatt tggaaaaaat
    54181 tcagcgggcg cttcctgatt tattagggac tcacgatttc acctcttttt gtgcatcagg
    54241 aagctcgata gaggataaag tacgtacgat ctacgaggct aagatggagg taaatgaaac
    54301 aaaagacgaa ttgttgttta catttagggg aaatggcttc ttgtataaga tgatacggat
    54361 cttagtagga acgcttttga aaattggcaa tggccgattg cctgaagata gtatcccaga
    54421 tattattgcg aaaaaagatc gtaatgcagc aggacctaca gcacatcctg aaggacttta
    54481 tttgtatgaa gtgaaatatg aataagaggt tgtgacagaa gtggtcagct tcaagaaata
    54541 agaaggaatt tacgaaaatt acttctcaaa attttgcaaa atttcggctt attttcgaag
    54601 gagctacttc tggaacaccg tgaatcagag gttgtgaaaa agctgccctg catcaagtaa
    54661 taagaacaac caaacaaaaa tagctcgtca tatttttcgt ttggttgggc ttattaccgc
    54721 agatgcaagc ttttgaacac cgtttaagga agaggttgtg aaatcagcgt tttgacctga
    54781 gtattagaga aacaaacgga aaaatagttc ctcatatttt gccgtttgtt gagctaatac
    54841 cgaaggtcag ctgattgaac accgtttaag aaagaggtcg tgagcctgtc atttaactct
    54901 gagtcacaag taacaatttc aaaaaacagc ttctcatctt tgatgaatat cgtgacttgt
    54961 ggacgaggcg ttgataagtg aatcatcttt ttgttaccta ttttttctgt aaccaaaaaa
    55021 cgatggaacg ttgttttgat tgcccttaat gaggacagtc ggaacaggtt tgtcattttt
    55081 atatttaaat ggcacaaatt tttctaatta tttgtcattt agcgctgaaa atttttgcta
    55141 tttatctaaa aaagtgataa ctacttaaga tgaagcagaa tatttacgcc atacggcata
    55201 caaccgcgaa aaatataaaa aaaagaaaac gattgaacgc gtttttgcag tcgcaaagga
    55261 aaagcatgga atgcgctaca tcaagtatcg agacttggaa aacaatcagg tgtatacgct
    55321 gattgttttt gctgcaatga atctgaaaaa gttgtccact tggcagttgg aacatatgtc
    55381 ttcatatctt ttattataca aaaatagcaa aagcaccagt ctacactctt agtaaagagg
    55441 aaactgatcc ttttgtctac attcttaaag tacttaaact aagtacttta ttttactctt
    55501 taggattgat acagtagcat ctatcccttt attaataatc ttttattttt ttaaataaag
    55561 atgttgtctc catcttcagg cactaaaact ttttcggaaa ttcctttttc tttattgaaa
    55621 gactttaatt cttctcttga cagtccccaa tggtttacag cttccatatg aacggcaata
    55681 attgtggaat ctggtattgc tttatgcaat tcatataaat cgtctttccc cataataaga
    55741 gattctccaa ctaaaaaatg attatctcca gcatttgcta ctatgatttc tggattatac
    55801 tgatcaatag tttgtttaac agcttcatac caaactgtat ctcctgtaaa gtatagtgtc
    55861 ttctcagtcg aatgtttgaa aacaataccg caaacattac ctacataatt caagatttct
    55921 cctctgccat gtttgccttt tgttttaacc aattgtatag attcaaaaac tgtgtcttct
    55981 cgtagtacct ccacattttt aaaaccatat agtcgaattt cattcgcatc attttcatct
    56041 tgcacaaata attttatttc tttaggtagg acctctttcg ctatatcgtc ccaatgatct
    56101 agatgtaaat gtgttacaat aacagcatca ataccgttga taatatcttc gactggcatt
    56161 ggcaaatcaa ctagaggatt catttgatct tttcttggtg atggaaaagg acctttcgaa
    56221 ataaatggtg gaagtgttcc tttttccgct aacattggat caattaaaaa ttttttacct
    56281 ccatagtcta agatagctgt tgcattacga atgtgatgta tattcataaa cgttgtctcc
    56341 tttttgttga tatgaaatat ttttagtata attcaattcc atacaataaa taaaccgaac
    56401 aaaaaaagtc ttttactatt tttacttaat ttatgaaagg ttgtttacca tgttagacca
    56461 aacagatata aatatcattg aggaactatc aaaaaatagt cgaatcacaa tgaaagaact
    56521 tggagaaaaa gtacatttga ctggacccgc tgtctcggcg agagtgacaa aactagagga
    56581 aagtggagtt attgaaaatt atacagtaaa attaaatatg gaaaagctag ggttttcgat
    56641 tcacgctttt ttaattataa ttacgcaaaa tttaaatcat aaaccctatt tatcatttat
    56701 taaaaatcat gaaaaattct tgattagaaa ttataagatt agtggagggg gctgttatct
    56761 tttggaatgt agatttactt caaaaaaatc aatgaacagc tttttggaac agcttaatga
    56821 atatgcgaat tataaattat ctattgttat agattaataa taaaactagc agatggtaaa
    56881 aatactaata tgcgagacac acattcaacc ataactatat aacttatcaa tttaaaacta
    56941 aactgatgga aacaagtaag gcaaaaacat ttatattttg
//
LOCUS       DAFLVO010000010        51257 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.010, whole genome shotgun sequence.
ACCESSION   DAFLVO010000010 DAFLVO010000000
VERSION     DAFLVO010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51257
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.010"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(56..1561)
                     /locus_tag="L1U99_000652"
     CDS             complement(56..1561)
                     /locus_tag="L1U99_000652"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HBN1211220.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLEFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(1653..2243)
                     /locus_tag="L1U99_000653"
     CDS             complement(1653..2243)
                     /locus_tag="L1U99_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1211221.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            2422..4068
                     /locus_tag="L1U99_000654"
     CDS             2422..4068
                     /locus_tag="L1U99_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBN1211222.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            4117..4836
                     /locus_tag="L1U99_000655"
     CDS             4117..4836
                     /locus_tag="L1U99_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBN1211223.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            5315..6262
                     /locus_tag="L1U99_000656"
     CDS             5315..6262
                     /locus_tag="L1U99_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1211224.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            6274..7194
                     /locus_tag="L1U99_000657"
     CDS             6274..7194
                     /locus_tag="L1U99_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1211225.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            7235..8692
                     /locus_tag="L1U99_000658"
     CDS             7235..8692
                     /locus_tag="L1U99_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1211226.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            9037..9651
                     /locus_tag="L1U99_000659"
     CDS             9037..9651
                     /locus_tag="L1U99_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBN1211227.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            9644..11368
                     /locus_tag="L1U99_000660"
     CDS             9644..11368
                     /locus_tag="L1U99_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBN1211228.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            11365..12816
                     /locus_tag="L1U99_000661"
     CDS             11365..12816
                     /locus_tag="L1U99_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1211229.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(13289..15442)
                     /locus_tag="L1U99_000662"
     CDS             complement(13289..15442)
                     /locus_tag="L1U99_000662"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HBN1211230.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(15444..16490)
                     /locus_tag="L1U99_000663"
     CDS             complement(15444..16490)
                     /locus_tag="L1U99_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1211231.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            16640..17929
                     /locus_tag="L1U99_000664"
     CDS             16640..17929
                     /locus_tag="L1U99_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HBN1211232.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            17942..20644
                     /locus_tag="L1U99_000665"
     CDS             17942..20644
                     /locus_tag="L1U99_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBN1211233.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            20629..21486
                     /locus_tag="L1U99_000666"
     CDS             20629..21486
                     /locus_tag="L1U99_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1211234.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(21557..22456)
                     /locus_tag="L1U99_000667"
     CDS             complement(21557..22456)
                     /locus_tag="L1U99_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBN1211235.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            22625..24796
                     /locus_tag="L1U99_000668"
     CDS             22625..24796
                     /locus_tag="L1U99_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBN1211236.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            24864..25205
                     /locus_tag="L1U99_000669"
     CDS             24864..25205
                     /locus_tag="L1U99_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBN1211237.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(25481..27235)
                     /locus_tag="L1U99_000670"
     CDS             complement(25481..27235)
                     /locus_tag="L1U99_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1211238.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(27246..28082)
                     /locus_tag="L1U99_000671"
     CDS             complement(27246..28082)
                     /locus_tag="L1U99_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBN1211239.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(28084..28767)
                     /locus_tag="L1U99_000672"
     CDS             complement(28084..28767)
                     /locus_tag="L1U99_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HBN1211240.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            complement(28926..30320)
                     /gene="uxaC"
                     /locus_tag="L1U99_000673"
     CDS             complement(28926..30320)
                     /gene="uxaC"
                     /locus_tag="L1U99_000673"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBN1211241.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            complement(30359..31858)
                     /locus_tag="L1U99_000674"
     CDS             complement(30359..31858)
                     /locus_tag="L1U99_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBN1211242.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            complement(31851..33272)
                     /locus_tag="L1U99_000675"
     CDS             complement(31851..33272)
                     /locus_tag="L1U99_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HBN1211243.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            complement(33332..34324)
                     /locus_tag="L1U99_000676"
     CDS             complement(33332..34324)
                     /locus_tag="L1U99_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1211244.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            34556..36754
                     /locus_tag="L1U99_000677"
     CDS             34556..36754
                     /locus_tag="L1U99_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1211245.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            complement(37212..38084)
                     /locus_tag="L1U99_000678"
     CDS             complement(37212..38084)
                     /locus_tag="L1U99_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1211246.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            38384..39358
                     /locus_tag="L1U99_000679"
     CDS             38384..39358
                     /locus_tag="L1U99_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1211247.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            39380..40072
                     /locus_tag="L1U99_000680"
     CDS             39380..40072
                     /locus_tag="L1U99_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBN1211248.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            40038..41546
                     /locus_tag="L1U99_000681"
     CDS             40038..41546
                     /locus_tag="L1U99_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBN1211249.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            41620..42723
                     /locus_tag="L1U99_000682"
     CDS             41620..42723
                     /locus_tag="L1U99_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBN1211250.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            42726..44063
                     /locus_tag="L1U99_000683"
     CDS             42726..44063
                     /locus_tag="L1U99_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBN1211251.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            44050..44928
                     /locus_tag="L1U99_000684"
     CDS             44050..44928
                     /locus_tag="L1U99_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HBN1211252.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            44925..45848
                     /locus_tag="L1U99_000685"
     CDS             44925..45848
                     /locus_tag="L1U99_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HBN1211253.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            45845..46255
                     /locus_tag="L1U99_000686"
     CDS             45845..46255
                     /locus_tag="L1U99_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HBN1211254.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            46259..47827
                     /locus_tag="L1U99_000687"
     CDS             46259..47827
                     /locus_tag="L1U99_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBN1211255.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            48067..49485
                     /locus_tag="L1U99_000688"
     CDS             48067..49485
                     /locus_tag="L1U99_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1211256.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            49497..50807
                     /locus_tag="L1U99_000689"
     CDS             49497..50807
                     /locus_tag="L1U99_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBN1211257.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
BASE COUNT        16518 a         9054 c        10466 g        15219 t
ORIGIN      
        1 aaatcacagt cccttttttt cttagaaatg ggaaaccact agtatataaa taccattatt
       61 cttcaatcaa ccgcttcacg attgcataat ccccttcata aggttcatct acaccattga
      121 ttttttgata gggatccacg ccttttcccg caataacgac tgaatcttgc ggagcgcttt
      181 ctgctaaagc gcgtcgaatc gcttcaggac gatccatttc ataatgaacg atcaaatctg
      241 gattagtaat tgcttcattg atttcttccg cgattttttt cggatcttca aatgctgggt
      301 catctgccgt caaaaaggcg atgtcagctg tttctgatag cacttttcca aaatcatgtc
      361 gacgggagat tgctttgttt cctgggctgc ctaatacaac aattacacgg ccatctggat
      421 gttcattttt ggcaaattcc agcaatgttt tcaagcttag ataattatgt gcatagtcca
      481 catagacatg cgctccattg gattggatca attgatccat tcggcctggt acacgagctt
      541 cttttaatcc gtcttgtgca tcttgactgg aggcacctgt tagtgctgcg gcaatgatcg
      601 cactggctgc attttcttgg ttgaatcctc cagccagcaa aatatcataa gcagtatcgc
      661 agatagctaa gcgatcttca tgagaagata aagtaaaacc gtgagtacct ttatctgaac
      721 ggatcacttg ataattgctt tcttccgaac gaccataagt gatcgttgga atctggaata
      781 gatcggctgt ttccctaagt aaatcaaaat agtcactttc atgatttaaa acaactgttt
      841 ttgaattcaa gatcaattgt cgcttgcaat agaaatagtc atcaaatgtc ggatgttcga
      901 tcggactgat atggtcaggc gagatattca agaagattcc gacatctaaa gtcaagccgt
      961 atacgcgttg tgttttgtaa gcttgtgaag aaacttccat cactagatga gtcataccat
     1021 tttcaactgc ttctgacatc atacgatata aatctaatga ctcaggcgtt gtcaaatggg
     1081 atttgaaata tgttttgcca tctaacgttg tattcatagt agaaagcaat gctgtttttt
     1141 tatttgttgt gtgatccaag attgcttttg taaagtacgc agcagttgtt ttaccttttg
     1201 ttccagtgaa tccgatcact ttcaatttat tttgcggata gtcgtaaaaa gccatagcaa
     1261 gaagcgccat tgctttacgg atatccgtta cgatgattcc tactgctgaa ttttcgtatg
     1321 gttgttctga tacataatat tgaataccct gttcgattgc tgaatccaaa tattcttctt
     1381 tgaaattcat tcctttacag aaaaacaaag tagaagcatc agcttttctt gaatcataac
     1441 ttaactgaag aaattcagct ttttctggta catcaagatg ccagcctctt gttgaaacaa
     1501 attcttttaa tagattttct tttaatagta aatgacggat gtcttctaaa gagaagctca
     1561 ttgattgatc cctcgcttta ttcaatttct tggtttatta tagcacactc tttttaatat
     1621 atcgtttgtt tccgctatga caaaatccag ctttattcaa attttcttga cacaggggac
     1681 aagcggatga gtattttcat aaacaatgaa ctgactgtaa tagataggag aacgaatagt
     1741 gtctccaaca atccaaaaac ataataattc aaaaagacga taagactatt ggtaagtaaa
     1801 agtccttgcg gcattggaag ccgaaaaaat ttgtggaaaa taatcggcgg tatcgttata
     1861 ccgccatttg aggccccgac tgtgtacaat gtgtaaaccc caagactgaa caaaagactt
     1921 cctgaaatca gtgaaaagaa atgtgaggag atcatttcca cttttggaac aatctctaaa
     1981 acaacaggaa aaagcagact tcccgctaca gtcttaaaaa atactgattt tcctaatagg
     2041 acagcggcta gaagcagcat cataagattg atgctccaaa cagtaactga gcgttggata
     2101 gaaaaggccg tttcaactaa atgtccgatg gcgcccactc cggcggaagc tatatcgtga
     2161 gggagcaaga accaattcaa tccaactgtg ataaagaaaa gacctaaaaa tataacgggt
     2221 agttttttta tttcttgtgt cattgatatc tcctataaat gttagccata aaaggctgta
     2281 tatttcttta ctttaccaaa aaaacgaaac cgaattcaaa aaaacaattg ttcttataaa
     2341 agttatataa aatcgattgc cagtttctgt tttaccaatt aaaatgatag taatgttttg
     2401 tagaaagttg gaatctgacc gatggataat caaagaaaac cagcattaga tcaattaaca
     2461 ccgcaagaaa aaatggcacg aggctctgct tggatgaccg ccagtaatat catttcaaga
     2521 ttgctaggcg ctgtctatat cattccctgg tatgcttgga tgggcgaaaa tgctaaggct
     2581 gccaatggat tattcaatat gggatacaat atatatgcat tgtttctact gatctctaca
     2641 gcaggaatac ctgctgcgat tgcaaaacaa actgcacgct ataattcatt gaatgaatat
     2701 ggcacttcac gacgattatt tatccgtgca ttacagatga tgggcgggct aggcctgttg
     2761 tttgctttgt tcatgtacat cgcctctcct tggctagctc atgcttctgg tggcggagaa
     2821 gaactgattc caacgatgcg ttctttgagt atcgctgtat tggtttttcc ttgtatgagt
     2881 gtgatacgag ggtattttca aggcaatcaa gaaatgatgc cttatgcgct gtcgcagatt
     2941 gtagaacagg tggcacgtat tttttatatg ctattggcta cattcatcat catgaaagtc
     3001 atggatggtg actatgtgac ggcggtcacg caatcaactt tcgcggcatt tatcggtatg
     3061 ctagcaagta ttcttgtcct tttgtatttt ttgaagaaac atcaagcgta tacatcggcg
     3121 tttattcact acagcgaaaa caaaataaat attgcaacga aggaattgtt gttagatacc
     3181 gttaaagaag cgattccgtt tattattgtg ggttcagggg taacgatctt caaattagtc
     3241 gatcagttca cttttatgaa gatcatgtct gcatccaccg agtattccaa tgcacagtta
     3301 ctggatcttt tttcgatttt tagtgccaat ccagataagt tgacgatggt agttattgca
     3361 ttggcaacat cgatcgcgtc tactgggtta ccgttgatta cagaagctgt tacgttgaaa
     3421 gatcgagtag gtctggcaaa attgacaagc ggaaatttac agttgttttc attttttatg
     3481 tttccggcga catttggtgt tatgttactt gcctatccgc taaatacatt attttataca
     3541 ccggattctc taggaagtaa tgtactgatc caagcaagtt ttgtaggact cttcctagga
     3601 ctatatatgc tagtttccaa catgctgcaa ggaatgtttg aaaacaaggc ggcaattaat
     3661 tatttggtta ttgggtttct agtgaaactc cttcttcaat acccagccat tcgtttattt
     3721 gaagtatacg gccctttatt ggcgacaatg atcggatttg ctgtgtcttg taccttgatc
     3781 ttaaagagaa tccatgaagt agcccgcttt aaaccaagtt ttgtctggcg caggacattg
     3841 ctgatcttta ttcttacctt gattatgctt ttggcttcgt ggatcacaaa gatgattttt
     3901 ggtgcttttt taaacgaaga tagcaaattc cagtctctat tgttgattct tgtagtagca
     3961 ggtatagggg ctttagtgta tggttattta gctttgaaaa tccgcttggc agaaagacta
     4021 ctaggaccag gaatagcgcg tttacgacat aaattaaaaa taaaataagt gaatcagaag
     4081 agctagattg atgctctttt gaaatggggg aaacgcatgc gtttagataa gtttttagca
     4141 gatatgggac ttggcagccg caaagaagtc aaaggattga tcaaaaaagg aacgatcgaa
     4201 gtcaatggac aagtggtgaa aagcgataaa gcgcaagtaa atgaattcga agatgcggtt
     4261 acttatttag gagaaatcat tacgtatcaa aaagattttt actacatttt gcataaacct
     4321 gcaggagtca tttctgctac tcaggataat catgatcaaa ccgtaatcga tttattggaa
     4381 gaccaggatt atcgggaaga tctttttcca gtcggccgat tagataaaga cacagagggc
     4441 ctcttgattt taacgaatga cggggtgttt gcccatcagt tactatcacc taaaaaacat
     4501 gtggagaaag aatatctagc tgaggttagc ggtataatga cagaagaaga tatccgttta
     4561 tttgcagaag gactgattat tgatggcgat gagcagacat tgccggcaaa actccaaatt
     4621 gatcaagtag atcaagagac agaaacttca attatccgtc tgattttgca tgaaggaaag
     4681 tttcaccaag ttaagcgaat ggtcaaagca gtaggaaaag aagtcttata tttaaaaaga
     4741 atccgtatgg gaaaattttg gctgcctaaa gatttgaata aagggcaata tcgacccatg
     4801 accaaagaag agctagaaca agtgagagaa aaataattga atggatagct aaaagaataa
     4861 gcagagtagt tgtagcgcca tctgaaaagc agacttgtcc gtctgacttt cggatggctt
     4921 ttttgtgaaa tttcggctta tttccgtaga agctacttct ggaacaccgt ttgttcggaa
     4981 taagggactg tgacaagact tttgttacag tccccattgt tccttgtgac tcagagttag
     5041 atagtaagga cacgatctcc ctaatactca ggccaaaacg ctgaattcac aacctctgat
     5101 aaacggtgtt caatcagctg accctcggta ttagctcaaa aaacggcaaa atatgaggaa
     5161 ctattttccc gtttttttct ctaatactca ggccaaaacg ctgatttcac aacctctcct
     5221 atactttgtt tcattttccc tatactttgt ttatttattc tcattattga aagcgctata
     5281 attacgttgc gaatgaatcg aaaggggttt ttagatgaaa aaacgaaagg ggttcaatca
     5341 tttttttatg aatctatggc gttataaagc acttgtcctg atggctgtac cgggtatgct
     5401 ttggatgatt tttttctttt acatacctgt aatggcgaat gtcgtagcat tcaaaaattt
     5461 tcatatttca gcagatgggt tcttggctag cttgagggaa agtccttggg tgggttggga
     5521 aaatttcaaa tttttatttt cttcggatca agcatttctc atcactaaaa atacaatttt
     5581 atataatgta gcatttatcc ttttgaatct gctgatctca gtcgtatttg caatcattat
     5641 gagcgagttg agaaataaac gactcgttaa agtttatcaa acgatgtcct tactacctta
     5701 ttttctatct tgggtcatta tcagttactt tgtttacgct tttttaagtc ctgacaaagg
     5761 aatattcaat cagtggatca ctggacatgg aggagaagct gtcaattggt ataatgaacc
     5821 gaaatattgg ccgtttatct tggtgttcat tggtacatgg aaagggattg gttataacag
     5881 cattatttac tttgcatctg ttatgggaat cgatccgact tattatgaag ctgctatggt
     5941 tgatggagct agcaaatggc agcagatcaa acatgtgacg ataccacaac ttattccact
     6001 aatgacgatt ttaacgattt tagccgtagg aaacattttc cgagctgatt ttggcctgtt
     6061 ttataacatt cctaggaatt ccggtgcatt atatgatgtg actcaagttt tggatacgta
     6121 tatctacaat ggcctgacat ccacaggaga ttttggtatg acggctgctg caggacttta
     6181 ccaatcagtt gtcggctttg tcttgttgat gatcacaaat acgatcgccc gacgttttga
     6241 tagcgattct gcattattct aaggaggaaa aaaatgaaaa aaaagaaagt ggagagagtc
     6301 caagtccgct ctttcaataa gacggctaat tttttctcta atataatgat tgcactcttt
     6361 gctatttcct gtattttgcc atttatattt gttatcgcca tctcttttac cgatgagtcc
     6421 atattgtcga ctcacgggta cagtttttgg ccagaaaagt tcagtatatt tggttatacg
     6481 tacttgttcg accagatgca ggataaaatt ttccaagcgc ttttcgtcac tgtacttgtt
     6541 actgttttag gtacactgat caatagcacg gctacttctt tatatgctta tgcgatttca
     6601 cggtcaaact ttccattccg tcgttttttt accgtttttt gtttgattac gatgttgttc
     6661 tcaccaggga tggtggccaa ttatcttgtt atgacaaatc ttcttcagtt aaaagatacg
     6721 atttgggcat tgatcttgcc aatggctgtc agtcccttca atattattgt gatgcgcaca
     6781 ttctttaaac gttcggtctc tgattcgatt attgaatcgg cacggatcga tggagctagc
     6841 gaactgcgaa tatttgttca gatcgtttta ccgttagctg ttccaggtat tgcgacaatc
     6901 agtttatttg ccgcattggg ttactggaat gactggttca atgctttact atacatccaa
     6961 gatgataagc tagttccact acagtatctt ttgatgaaaa tccaaagtaa tattcaatat
     7021 ctgacacaaa attcaggagc aggaagccaa ttgacaggcg gattagcctc agttccagga
     7081 gaatctgcca gaatggcgat cgtagtcatc tcgacgttgc ctattgcgat cagctatcca
     7141 tttttccaga agcattttgt caaaggtcta acaatcggcg gagtaaaaga ataaagaaac
     7201 aaaaatataa atcataaaat taggaggaag aaaaatgaag ttatggaaga aactagcctt
     7261 tacaggtgtt tcagcgttgt tgttgggaac attagcagca tgcggaggtt ctggttctaa
     7321 agaccaggca gaagctagca attcggacac tttgcagatg tatcaaatcg gagataaacc
     7381 agataatttc gatcaattga tggaagtagc aaacaaacga atcgaaaaag agatcggtgt
     7441 aaaagtcaat atcaattaca ttggctgggg cgattacgaa aagaaaatga acgtcatcat
     7501 ttcttccggg gaaaattatg atatcgcctt tgcgaacaac tatgtttcca atgcccaaaa
     7561 aggagccttt gctgatttga ctgaattagc gcctaagtac gctgaaaaag cttataatga
     7621 tttagatgaa gcatatatta aaggaaatct ggtcaatgga aaattatatg ctttcccagt
     7681 caatggaaat gtctttgctc aacaagtact tacttttaac aaagctttac tagataaata
     7741 cgatctttca attgatggaa tccaatctta cgctgatgca gaaaaagtct tgaaggaatt
     7801 ccatgaaaaa gaaccaaaca cggcagcttt tgccattgga caaggcttca aagtccaagg
     7861 gaactttgat tatcctttag ggaatacgtt accatttgct attgatctgg atggagatga
     7921 ttcgaaaatc atcaaccaat acgataatga aacgtatatc ggactgttac gtacaatgca
     7981 tagctggtac aaacaaggac tcattccaag tgacgctgca acgagcaata aggattatcc
     8041 actagaagga aatacttggc taatgcgtgg agaaacacaa ggaccgtatg attatggcga
     8101 tacaattttg acaaatgcag caaaacaaga acttgtctca aaagcaatta ctgttccact
     8161 aaaatctaca gctcaagcac aaatggcaaa ttttgtcgta tcaaatactt caaaaaataa
     8221 agaaaaatca gtagaacttc tagggctgct taacagtgat ccagaattat tgaatgggct
     8281 tgtttggggg atcgagggag aagcatggga aaaagtcgat ggttcagatg ataaaatcaa
     8341 attgctagat ggttatcagc caaatacaca tatgtctgct tggaatacag gaaacaacaa
     8401 gattctatat acacaagagt ctattacgga tgacatgatt gccaaacgtg atcaatcgat
     8461 tgctgatgca gaaacttcac cgattttagg attcagcttc aacactgaca gtgtcaaaac
     8521 agaattaagt aatatttcta atgtcatgaa tcaatattta gatggattga atacagggac
     8581 tgttgatcca gatgaaacat taccgaaatt gaaagacgct ttggacaagg ctggctatga
     8641 taaggtattg aaagaaatgc aaaaacaata tgatgagttc cgacaagaat aataatgaat
     8701 aaagacaaag gggttgtgac aaaagacgtg tcacaacctc ttgttccgaa taaacggtgt
     8761 tcaaaagcca gtttctcggt attaagctaa atatatgtaa aaatgtggaa agccatattc
     8821 acaaaatttt tcttactact cgaaactaag cggctatttc acaaactctt ggtaaacggt
     8881 gttcaatcag ctaaccctcg gtattcgctc acaaaacgac aaaatatgag gaactatttt
     8941 tccgtttgtt tctctaataa tcaggtcaag gtgctgattg cccaaccttt ttttgtataa
     9001 tgagaaagta taaacttaat gtttggagga gaagatatgt tagggaaggt tttggaagag
     9061 ttatttatcc ggatctgggt cattataaaa ctaaccttgt atttctggat atatacattt
     9121 gccggcggga tcatctttgg attaggtgcg gcatggaaaa cagtcaatga actattttat
     9181 ttgtacggat tcgagtataa agaaatcaca ataaaaagag gctggaatat atataaaaga
     9241 aattttttaa gaggcaatct gctatttagt ttatttttat ctggtactgc tttattgagt
     9301 tacaatttat atttatctgt tcaaatcaaa gggctcattt ttttagctat tgattttatt
     9361 ttactttttg ccttgctctg cctatttgct acttatcaat acagtatgat tttagatagt
     9421 gaatatacga tctctgttcc taatctgcta aagctaagtt ttatttcggt tttttccagc
     9481 ttttcgtctt ttctaaaaat aattattggt agcggtataa ttttaggcgt gacttggcaa
     9541 ttcaaaggat tgatcctgtt tggtgtcatt ggtcttttga cggtttggaa tggtacgatg
     9601 acaacacatt ggcgtgaaga attagataaa cagttggaaa gttatgaata agtttcggat
     9661 tctattttca aaaggaacct tactaaatcg tctgttgcgg aaatacgcgg ttatcatgat
     9721 cggtgtaacg atgactgcta ccgttatttt tagtatccat acttgggaac aaaatcaaaa
     9781 acaggcagaa aacatgacaa gtgatgccgt tcaaagcaca agcagaatgc tgaatgataa
     9841 aacaaccttg agtaggatca tcaaaaacca gcttgtaggg aattccgaaa agatcgaaaa
     9901 tgtgacgacc tacttaacaa aacccataga tcagtatctg atgtatgtat acgaacagca
     9961 aaacagtacc gatgaattag tttctttccc aaatcaaatc aaagatctct acgcaaatta
    10021 tgaagaacta agtgcgatat atatcgtgtt gaatcaacta ccggagtatt atgaatcttc
    10081 tagagaaaac aaaggtgggg aaataaaaaa ggggacacca aaattactag acgcctttta
    10141 tatcaagttg cctatcacac aaggaggagc tgagtcagga agtattttta ttggttttca
    10201 aaagaaagaa ctagatatga ttttagaaaa tctaacgtca ttcaatggac tctctttata
    10261 catgatttct ggaacgacaa atcgactata cacattccat gataataaaa tagctaaaga
    10321 aacgtttgaa agacaagaaa tgatcatcac agagagtctg aagaaaaatt cacaattgcc
    10381 gattgacgat ctggaaaaaa acaattttgt tcaacaccaa gaactgtctg atgattatcg
    10441 tatattagct gtactagata aaaaaagtgt aaaaatcgaa acgggaaaaa atcttgcccc
    10501 gctgatcatt ggtatcatta ttttagacaa tatactgctt atctttcttt ataaaacatt
    10561 caaacgatat tcacagcaag tatctatcgt catgcaggcc atggatcaaa cagcagcagg
    10621 gaatttagag acgcggatcg acataacaaa cacggaatat gaactgaagg aactttcaat
    10681 cggtatcaac gaaatgttgg atagcatcaa tcagtttgta gaagacatct acaaattaga
    10741 aatcaaacag caagacgcac atatgcgggc gcttcaagca cagatcaatc cacacttttt
    10801 atataataca ttagaatata tccgaatgta tgcaatcagc gaaggaagtg aagaattagc
    10861 agatgttgtg tatgcgtttt ccgctttgct tcgaaacaat acgaatcaag agaaaacgat
    10921 cactttaaaa gaagaactgg acttttgcga aaaatatgtc tatttgtatc aaatgcgtta
    10981 tcctaatcga gtagcctatc attttatgat cgatcctgat ttggaaaaga tcgaagtacc
    11041 taaatttgtg atccagccat tagttgaaaa ttattttaaa cacggtattg attttactcg
    11101 attcgataat gcgctaagtg tcaaagtctt gcaggaaggc aaacgggtaa ggatcatcat
    11161 caaagataat ggaaaaggga tgactgaaaa acggctaaaa cagattgaag aaaaactgtc
    11221 tcatcctaaa gtggaacttc acggttctat cggtctgcaa aacgtgaatg aacgtttacg
    11281 tgccagcttc ggcagcagtt attatatgtc gcttgagaat aatgagacag gtggactgac
    11341 cgtttctatt acattcaagg agggatgagc gtgtatcaag tgttattggt agatgatgaa
    11401 tacatgattt tgaatgggtt aaaaaagata attgattggc aaagtttagg ctttcaaata
    11461 gtagcaacag cagagaatgc caaagaagga ctagctgtac ttgaacagcg acagattgat
    11521 ttagtagtaa cggatgtgac aatgccagaa ataaatggac tggaatttat tgaagcggct
    11581 caaaaagaac gtcataattt tgaatttatg attttatcag gataccaaga attcgattat
    11641 ttgaaaggag gtatgcaatt aggcgccgtg aattatttga tgaaacccgt gaataagttc
    11701 gaattggttg aaagcctcaa gaaaatcaaa acacggttag atcagcaaaa tgaacaaaaa
    11761 aatcaacaag aaatctatca agaactgtta ttcagtcaat ggttgaatga agaattggat
    11821 gaaataagtg aagaagaaat aataggacaa ataagtgaga agcagcatag gatagtattg
    11881 attcaactgg caagaactca tgatactctt atcaatagat ggttgcaaga acggcaacaa
    11941 atcttttact atcaacgaaa ttacggagac cgtgtattga tcacgttgtt gttggaggca
    12001 gatgaagttg atggcttctg ttgttttgtt caagaaaact ttcctgatca ggaatggctg
    12061 atcagtatcg gggaagagac agattctttg gacaaaatcc ctgaaacatt ccaacaagcg
    12121 aaagacaatc tacagttgca tcaattttat ggagataaag acgagcatgt tttttacgca
    12181 gtacaagcag aaacaaaaga tcaaaccatc gatttttcaa gtttcagacg cgtgctgcaa
    12241 aataaacaat tggaagtcgc tcaaaaaatg atcactgatt tttttgaaca gtttcagtta
    12301 gcagccatga tgccggaaga tatacgatat tccagttttt tactgtttat ggagattcaa
    12361 cgggaattga ttgatctgga agatgaggaa tatttacaag gaatcgaaaa aatccatcag
    12421 gcaaaaacgg tgcaagaact tcagcagcta cttctgtcat tcatcaaaaa gcatcagaga
    12481 cagaaaaagt acagtgacaa tgtggaaaaa gtaatcgtaa tcctgcacca gcattatcaa
    12541 gaaccactta cactcaaaga agtgtcagaa aacctgcatt taaatgtcat gtatctagga
    12601 cagctgttca aaaaagaaac gaaaaaaagt ttttcagctt atttgaacca tttacgtatg
    12661 gaaaaagcga aacaactgct tttgcacagt aatcaaaaca tcaatgagat agcaagtgag
    12721 attggctaca acaacaccac gtatttctct aaattattca agaaaatcgt cggcagatcc
    12781 cctaaagagt accgagaaaa cagtggagaa tcataaaaaa aaaagccaat gtaatgaaat
    12841 aacttataaa aaattgtcta gaaatctaat tttgggctgt tcttattact tgaggcaagg
    12901 cagctttttc atgacctctc gataaacgga gttcaaaagc cagtttctcg gtattaagcc
    12961 aaatttatgc aaaaatgtgg aaagccattt tcacaaaatt tttcttaata ctcgaaacta
    13021 aacagctttt tcacgacctc tccactaaat ggtgttcaat cagctgaccc tcggtattag
    13081 ctcaaaaaat ggcaaaatat gaggaactat tttgccattt gtctctctaa tactcaggtc
    13141 agaacgctga tttcacaacc tctcaataaa cggtgttcaa aagcttgcat ctgcggtaat
    13201 aagaccaacc aaacgaaaaa tatgaggatc tatttttgct tggctgttct tattacttga
    13261 tgcaggacag ctttttcaca acctcttgtt aattatagtt tgataaggaa aaaggcaaat
    13321 cttttgcttg atatttctta gggtgaggga tgatccctaa ttggtaagag atcgtgccgc
    13381 ctttcagcaa atcttgatgg gtaaaatata atttcgtata ttctctgtcc atccgtttga
    13441 ttttatggat aaattgttgc tgcggccgat taggcgttgc ttcaatcgtc aattcctttc
    13501 catttgacaa aagcaaaaca gccttgtcaa ttaatggcat accgataaca tattcaccgg
    13561 ttccaggcgt gacaggataa aatcccagac tattgaagat ataccaagcg gccatacttc
    13621 cattgtcctc atctccaggg taacccattg gagaatcgtc gaaggtctga gtcatcaact
    13681 gtttaagcag tggctgtgcc atttcaggtt gtcctatata actgaacaag taaggatagt
    13741 gaaaacttgg ctggtttgaa atagctaatt gtccaaattc tatcgcggcc atctcactca
    13801 tttcgtggat ctcaaaacca tatcctcctg ggtcaaacgt tgggggctga ttgcacagct
    13861 caatgagttt ttctttatat ctctcactgc caccatattt tccgatcagt cctgaaaaat
    13921 cgtgataaac agcaaagctg ctttgccaag cacttccttc tgcataatct tgtccccaac
    13981 gattagctga aaatggttct ctgaacttgc catctttatc ttttgaacgc ataaatcctg
    14041 actcatagtc aaagatattt tgatagttca atgattgctg ctgatatttc ttcgtcattt
    14101 cctcttcttc tagtaccttg gcaacttggc taatacaaaa atcgctataa gcatagtcta
    14161 atgtgtgatt gactgattcg tggtagtgat taggaacata gccatatgtc aagtaatctt
    14221 ctgttccttg gcgtccataa tttggatgtt tgctttgaac cgtagcacct ttttccattg
    14281 ccgttagaaa ttcaggcatc aagtctcgtc ggatatcttt tacagcagca tctgcaatga
    14341 ccgcatcgat caatgtccca ggcataagtc cacgttcatc aggagacagc cattttggca
    14401 aatagccact ttctctatag ctgttcaaaa aaccttccag catttcttcg tatttttcta
    14461 cagcaatcaa agaataaaga ggataaaccg ttttatacgt atcccaaaac ccattatttg
    14521 tatagagaac accaggtttt atagatcgac tagtcgtatc atagtggatt ttttgcccac
    14581 taggatcaat ttcataaaat gtttgtggaa ataaaaacac ccgatataaa ttatgataaa
    14641 acgtccgcaa ttgttgttga tcatggtgtg tgagctgtat acgatcaaaa taggactgcc
    14701 attgttcttg actgtgagca aggtaagtct ctttgctttg gttttgttct agttccaggt
    14761 tataagctgc ttgttccgag ctgataaaag atgtcccaaa tcggatagtt tgtttttttg
    14821 tctgttcaaa atacaacggg atcgagtcgc tatttttgtt ggaaacagct aactcatcaa
    14881 ttgttaaagg atattcaaat ctcaatataa aataaaaaga aaaatcagga tcttctgaac
    14941 cagcaaaatg tgtgattttt ccttccactg tgtaaggatc tataacaaag agctgatggc
    15001 gtcccggaaa ggataaaagt aaaccgctgt catttttgct gtaatcaata gataagattc
    15061 cgccatacat gctaggtatc aatgtagaac agatgccata acgtaattga cagatcgaca
    15121 gatgagtcgg gcaaaatata ctttcttctg ggcggtaaga actttgagca tggaaaaggg
    15181 tgttctcctg tagttttcca ttgatcggcg taaacagcat atgactgaaa tcacccatcc
    15241 aaggacttgg ttgatgggta agacggtagc cttgaaaaac gcggtcatca ggatgaaacc
    15301 accagctgcc gttttgatcc gtagtttgcg gtgcaaaata attcatccca aaaggaacgc
    15361 cagtataagg ctggcagttc ccattagaga aatttggctg attcgctgtt gcatgtctag
    15421 tatctatttg accgatattc attttatttc tcctttgttg attgtctttt gatgaatgaa
    15481 actggaaatt tactatcgga tggtcgatct tttgtctcta accaagtgac caaagcatct
    15541 cccgcaagct tacctaactg ttcaaaatct tgtgcgatgg ttgtcagtgg cgggtcaaca
    15601 agagctgctg cttggatatc atcaaatccg ataattgaaa aatcttcagg gatatgataa
    15661 ccatgctgtc tcaagagatt catggtctgg atagcgacaa catcgttttc acaaacaaaa
    15721 gcagttactt catacttagt gatataagaa agcaattcat ctaatgtcgc gcttttgtca
    15781 tccagtgaag tgtggaaagt caaaccagct ttgtccaatg cttcaaggta accaaggtaa
    15841 cgctgtcgaa cggattgtgg atgagtctgc gtaccaaaca aataagcgat ttttgaatgt
    15901 ccctgttcga tcaaataaga ggcagcaagc gcaccgcctt ggaaattatc ggaaagaacg
    15961 gtaggaaaag gtaactcata gattttttta tctaatatga cgacagggaa ttctttcaat
    16021 gaaagctcaa aaagtaagtc aagatgttgt tctgtatcaa gagcataata aatcaatccg
    16081 tcaaattcat tgattagctc ttttgctgtt ttattttgta gaaagtcaag cgtcgtcatc
    16141 atgacatcaa tctgtttatc ttgcatcaca gggttcaatc ccttgctaaa atcaccaaca
    16201 gacaaatcag cgacatatgg aagaagaaac agaatccgtc gtgtttttgt aggagaagca
    16261 agaatctgtt ccggagaagc ggatttaacg aaactgcctt tcccgcgaac gcgataaata
    16321 agtcctaatt gctctaattc agtcaatgca cgtttggaag tgattctgct tactttatag
    16381 gtacgtgaaa gttctttttc agttggtagt tggctgtcta caggtaattc accagttaaa
    16441 atagccgttt gcaaatcatt aaatattgtc tggtacaatg gttgagtcat ataaacacct
    16501 cttaatgata tatcatattc aaataatacc ataatggatg aaaaagtaaa taaaaagata
    16561 ttttttgaaa gcgtagacat aattggctgt atgaagtata atctttaaag atatatcaaa
    16621 tagaaagaag gttttattag tggtttataa agatatacca aaatcggtgc agaaatttat
    16681 ggaagatatc acacaaaaat gtggggatat ccatgcggac tgggcaaaga attttacagc
    16741 agcatttgcc aatactctgt tgacaacagt caaaaagcaa aatgacggaa ccaccttttt
    16801 attgacggga gacattccag cgatgtggtt aagagactct actgcacaag ttcgtcctta
    16861 tttagtgatt gcaaaagaag atgaggaatt agctgacatg atcagcgggt tagtcaaaaa
    16921 gcaatttttt tatatcaata tcgatccata tgcgaatgcc ttcaacgaag aagctaacgg
    16981 tgctggccac caaacagatc atacaaaaat gaacgattgg atctgggaaa gaaaatatga
    17041 aattgattct ttatgctacc caatacagtt ggcctatctt ctttacaaaa atacaggaaa
    17101 aactgatcaa ttcaatcaat cttttattga aggtatcaaa aaaatcttgg acgtgttcaa
    17161 aacagagcaa gatcatgaac actctcctta tacatttgta cgagacacga caagaaaaga
    17221 agatacgctg atcaatgacg ggcgaggtgc aaaaacagct tttacaggaa tgacatggtc
    17281 tggtttccgt cctagcgatg atgcttgccg ttatggatat ctggtaccat ccaatatgtt
    17341 tgcggtggtc gtgttaggtt atgtggaaga aatttttcaa acgatactcg atgataaaga
    17401 aattgtacag caaacacaga aattgaagaa agagatccaa gaggggattc agaatcacgg
    17461 acgaacggtt aatcaaaaag ggcaaacgat ttatgcatat gaagtagatg gaatgggaaa
    17521 cgccacagtc atggatgaca gtaatgtgcc caatctgatc gccgcacctt acttgggata
    17581 ttgttctgaa caagaggaag attatctgca aacaagaaga acattgttga gtaaagaaaa
    17641 tccatatttc tatgaaggaa agtacgcaaa aggaattgga tcctcccata cgccagaaaa
    17701 atacgtttgg ccgattgcat tagctatgga aggaatgaca acgtcagaca aatctgaaaa
    17761 agagcggata ttgaatttac ttgtagcaac tgacgcagga acacacctta tgcacgaagg
    17821 attcgatgtg aacaatcctg aaaattatac gagagaatgg ttttcttggg caaatatgat
    17881 gttttgcgaa ttagtcatgg attactttga tattagagta gaaaagtagg aggtatcgta
    17941 aatgaaaaag aaagtatata tcatttctca tagccactgg gatcgtgaat ggtacatggc
    18001 ttacgaacag catcacatgc gactgattga attgatagac gatctactag agctatttga
    18061 agttgatccg tccttcaaca gttttcattt ggatgggcaa acgattattt tagatgacta
    18121 tcttcaagta aggccagaaa aaagacaggc aatccaacaa gcaatcaatg aaggaaaatt
    18181 gagaattgga ccattttata tcttgcaaga tgattttctt atcagctcgg aatcgaacgt
    18241 gagaaatatg ctgattggca tggaagaaag ccgtaaatgg ggaacccctg tcatgttagg
    18301 ctattttccc gatacatttg gaaatatggg acagacgcct caattaatga aacaagctgg
    18361 tatttcagca gcagcgtttg gccgtggtgt aaaaccaatt ggctttgata atcaagtttt
    18421 ggaagcagaa aactattctt cccaatactc agagatgtgg tggaaaggcc ctgatcaaac
    18481 agcaatcttt ggtctgctat ttgccaattg gtatagcaac gggaatgaga ttccagtaga
    18541 aaaagaagca gctcttgcct tttggaagca aaaattagcg gatgcagaac aatatgcctc
    18601 tacgaaccac ttattgatga tgaatggtgt tgatcatcaa ccggtacaaa aagatatatc
    18661 aaaagcaatc catctcgcaa atgaactgtt tccagattac gagtttattc attctaattt
    18721 tactgactat ctggaagcag ttcaaaaaga tgtgccagaa gacttaggct cagtagaagg
    18781 agaattgaca agtcaagaaa cggatggctg gtatacttta gccaatacag catctgctcg
    18841 ggtttactta aaacaatgga ataccaaggt ccagcgacag ctagaaaata ttacagaacc
    18901 acttgcgacg atggcttatg aagttagtgg aaactatccc catgatcaat tagattatgc
    18961 ttggaagaca ttaatgcaaa atcatcctca cgacagtatt tgcggttgtt cagtcgattc
    19021 tgtccatcgg gaaatgatac ctcgttttga aaaagcagat gaagttggaa agtatcttgc
    19081 acaagattcc ttagaacagc tgaccgcagc aatcgatacg accggattcc caaaagacag
    19141 ctttccattt gtcattgtaa atactgcagg aatggataaa actggtgaag cagaaataac
    19201 catcgaatta gaaagaaaaa gattcgctga aggaatacct gaacaactat atcaagagtt
    19261 agaaaatttg cctaaacgta agtatcatgt agaaacaaaa agtggggcca ctataccagc
    19321 tattttatct gaagaaactg tccaatttgg ttatgatttg ccgaaagacc gtttccgtgt
    19381 gccatatatg gcaagaatga tcaaagtgac tttaccatta gaaaacatgc cagcattttc
    19441 ttgggaaaca ttcgcgcttg tagaagggga agcgaaagca gaagaaaagg aaacaatgat
    19501 tcatcagagt ggacgaatca tcgaaaacgg ccctctacat ttgacgattg aaaaaaatgg
    19561 taccattaca atggaagatc gcaaaaacaa acgaaagttg aataatctgc atatttttga
    19621 agatatcggc gatataggaa atgagtatat ctttaaacaa cctttctgtg atcagccaat
    19681 cctatccagt aacaaagaaa actctgaagt aaaagtatta gtagatacac cggaaatagc
    19741 aaaaataagt attctacagg aaatggaaat ccctgtttct gcagacgagc gtttagaaaa
    19801 agaacagcag atggttgtgg aatttcgtta tcgaaaagca gaacgatcca aagaaaaacg
    19861 aatccttcaa ataaaaacaa tcatgacaat cagaaaagat agtaaaaaaa tcgactttga
    19921 aacgactctc gacaatcaga tgaaagatca tcgcttacgt gtcttgtttc ctacaaagtt
    19981 acatgtggaa catcacgaag cagatagtat ttttgaagtg gtgaagcgcc caaaccatgt
    20041 gtctaaaagt tgggaaaacc ccacgaatcc gcaacatcag caagcatttg tcaatattca
    20101 tgatgaagag tacggtgtaa cagtcggaaa ctttggtttg aatgaatatg aagtaacaga
    20161 agacggacaa atcgcagtga cgctacttcg cagtgtggga gaactaggcg attggggata
    20221 ttttccaaca ccagaagcac agtgtctagg tgagcatcgg ttcaattaca gcattgaact
    20281 acatggacca gaagaaaaat tctctactta tttgcatgca tacgcagcac agattccttt
    20341 ttccactcaa caaatcaaac atcatgaagg aacattgatt tcaaaacaac aatatttaac
    20401 gataaaaagt gaaacgtttg caattacagc tttgaaacgc agcaagttta gtgataaagt
    20461 agtagtaaga ggtttcaata tgtctagtca tttagaaaaa ttggaaataa ctaaagacaa
    20521 tggaaaaact gtcatattga atctgcttga agaaccaacg aagcaagcgg ttgtcccaat
    20581 aatccaacct tatgagattc ggacaatcgg attcgaggag gaaaacgaat gtatggcgga
    20641 atagaagcag gcggaacaaa atttgtgtgt gcggtttcag atggtggaga aattttagaa
    20701 aaattaagta tccctaccac aacaccagaa gaaacattgg atcaggtatt tgaatttttt
    20761 gatcgttatg aattgaaggg aatcgggatt ggctcattcg gcccgattgg tatcgacaaa
    20821 acaaaagata attacggata cgttttggca actcccaaaa aagggtgggc acaattcgat
    20881 tttcttggca caatcaagga acgctacaat attcctgctg cttggacaac ggatgtcaat
    20941 gctgctgcat atggggaatt gaagcaagga gcagcacaag gaaaaaatag ttgtatttac
    21001 cttaccgtgg gaacaggaat cggtgcaggt gtcgtgatca atgaagaaat tttttcaggg
    21061 atcgcacatc ctgaaatggg acatatttgg gtgaaacgcc atccagatga ccattatgaa
    21121 ggtacttgtc cttatcataa agattgttta gaaggattag cagcaggacc gtctattgag
    21181 gcacgcacag ggatcaaagg gcaagatctg ccgcaagatc atcctgtttg ggctattcag
    21241 gcttattata ttgctcaagc actgatcaac tatacgttga cgttagcacc tgaaaagatt
    21301 attttaggcg gtggggtaat gaatcaggat catctccttc aaaaaatccg tcagcaattt
    21361 gttgaattga tgggtggtta tatggaaaca cctcaagtaa gtgaatatat cgttcgttgg
    21421 ggactgccga atgaaagtgg gattatcggt agtttgctgt tagcagaaca cgaacatcaa
    21481 aagtaagcag acaaattaca caaaaagaac agagtcttat cattatctgc tgataagact
    21541 ctgttctttt ttatttctat tcccataatc caggtaaagc tttaccgact attttttctt
    21601 gagtaaatgg atggatcatg tgcagttcta atgcatggag catcagtcgt tcagctgttc
    21661 tattttggta gagagggtct ccaacgatcg gatgtccctt atgagctaaa tgaactctga
    21721 tctggtgtgt acgtccggtt tccaaaacac aatagacttg tgtttgttca gaaagtactt
    21781 tgttgacagt gacatgtgtc aaggcgctct gaccattttt atcatctacg accctttttc
    21841 tccgatcatg gcgatctcgt ccaattttat tggtgatggt catatctttg gcaatttctc
    21901 cccatacgat ggcttgatat ctccgataga tcattttttg ttccaacatt cttccaagta
    21961 tcggcaagac aaatggattt tttgcaaata aaacggcacc gcttgtttct ttgtccaagc
    22021 ggtggacaac gtaaggtcgt tgctgtttag tgtcgagata agcagctaaa tgattgagta
    22081 aggtactgtt ttctgtcggt tcatttggat gagtcttcat tcctgcaggc ttatccacta
    22141 taatcaaatg ctcatcttca tataaaacac ggatgtgctt cgcatctcct aattgaactt
    22201 cttgataatt ataatctgtt tcttcgaata acaatgtgat ctggtcattg ccctttactt
    22261 catgatggaa caaagcaggt tgttgattga tccaaacgtt tttacgtata cgcaaaaagt
    22321 gtcgaacctt tctaggaact aaccattcct tttcaagcaa gtcgcgaatt gttgtttcag
    22381 gatggttcat aggtaaagtg atcgtgattt tcacaagtgt actcctttca gtgcaatcgc
    22441 agactaattg taccattttt aaaacatatt taagaaaaaa cttacatttt tctgttcatt
    22501 cttatgttac tctacttgca ctaacgtaaa aaaacatatt gaactacaac ttaagcagga
    22561 agaaaacact ctttcactat ggtaaaataa gacgattgaa tcaaatagac aggagaagaa
    22621 gcaaatggat tttcaaagca ttttagaaaa gataaaagct gctttgatca gtttttggcg
    22681 ttggatcaga ccatatctcg gacaattcca tcgatggcga aagcgcatct ggaaaaaata
    22741 tcatgtgaac aaattgattt tgctgattgg tttgatctgt gtcttagtga caagtatcta
    22801 cctctttatt ttagcaaaac aagcaaatgt cgaaacgtta aaatcaggat taagccaatc
    22861 gacagtcatt tatgataaga aaaacgaaga agctggcaca ctgtacgccc aaaaaggaac
    22921 atatgtagaa ttaaacgcga tttctcccta tatccaagat gcagtaatct cgacagaaga
    22981 taggaatttt tacgagcatc acgggtttga tatcaaaggg attgcccgtg cagcagtccg
    23041 aatggtcttg tctggcggaa catcaggggg cggaggaagt acgatcactc agcagcttgc
    23101 caaaaatgcg tatctgacat tagaccaaac gtttgatcga aaagcgaagg aattattttt
    23161 ggcaatcgag atcgaaaaga agtacagcaa agaagaaatc ttgaccatgt atcttaacaa
    23221 tgcctatttt ggcaacgggg tatggggtgt ccaagacgct tccagaaagt attttggagt
    23281 agatgcaacg aatgttacgc tgtctgaggc tgctactttg gcaggaatgc tgaaaggtcc
    23341 tggtatttat aatccgatcg atcacccaaa aaatgcgaat gatcggaaaa acacagtact
    23401 aagtgtaatg gaagaaaacg gaaaaatcac aaaagaacaa gaacaagcag aaagccagac
    23461 agatatcagc gcgtatctta atgacacata cgataattca gattctggtt atcgttatcc
    23521 ttattatttt gatgcagtga tcgatgaagc agttaacgag tatggtcttg atgaagaaga
    23581 tgtcatgaat aaaggctata aaatctatac agctttagat caggattatc aaaagcaatt
    23641 agaagctact tatcaaaaca gtgcattatt cccagcaaat gcttcagatg gtgccatggt
    23701 ccaatctgct tcagtagctt tagatccgaa tacaggtggt gtacaagcac tagtaggacg
    23761 aagaggagat catgtcttta gaggattcag ctttgctaca cagatgcgtc gttcaccagg
    23821 atcaacgatc aaaccattaa gcgtatatac accagcactg gaagctggat acaagccttc
    23881 cagtatcttg aaagacgaac cgcaaagtta ttacgatgcg cataattttg acgggacata
    23941 ccaaggagaa gtaccgatgt atcaagctgt tgcacaaagt ttgaatttgc ctactgtatg
    24001 gcttttgcat gagatcggtt tacaaaaagg atatgataaa gcagaagaat tcggcctgcc
    24061 tttagcaaaa tctgataagt attatggctt agcccttggt ggactggaaa aaggagtatc
    24121 tccattgatc atggcgggtg cttacagtgc atttgccaat gatggtcaga tgtatacgcc
    24181 gcatcttatc acgaaaatcg ttgattcgac tggagcggtg atcgtcgata acacaaacaa
    24241 aaaaccaaaa caggtcatat caaaggaaac agccgatgaa atgaccagca tgcttcttgg
    24301 tacattttca aatggaacag cggctgctgc gaatcctgca ggttatacga tagcagggaa
    24361 aacaggaacc acagaaacta atttcgatgc cacaaaagca aatgaccaat ggatgatcgg
    24421 ttacacgcca gacgtagtga tttcgacatg gatgggttac gaagaatcca gcaagctgca
    24481 ctatttggaa gggacaagtg gaaatgttgt cgggaaagtc ttcaaatcag cggcagaagg
    24541 catccttccg tatacttcaa aaacaggatt tagtgtagca gatgcctatg ccacaggagg
    24601 acaagtggta gctgcagatc aagttggaaa cacaggaaat tctaatggag agtctggaaa
    24661 ttggcaagat aacttgaatc aatatggtga acaagcaaaa gaagggctga aaaacttcgg
    24721 cgatatggtg aaagaaggcg ttcagggaat tggtgaagcg gctaaagacc tctggcggaa
    24781 atatcaagga gagtagcccc tttgaaaacg aataacccca tgttacaata gagagtaact
    24841 actaaaagaa aagagggcat aacatgtcaa acatctacga tagcgcgaat caaatcgaac
    24901 gtgagatccg tgaattacca gaattcaaag cgttgaaaga agcgtacgag aaagtacaag
    24961 caaacgaaga agcacacaaa ctgttcaaag acttccaagc gatgcaaatc gaattacaag
    25021 aaaaacaaat gagtggacaa gagttcagcg acgaagatgc aatgaaagca caagaaatgg
    25081 ctgtgaaaat ccaatcagaa gaagtaatca atgacttgat gcaaaaagag caaggcttca
    25141 gtacaatcat caatgacttg aaccgtatca tcatgacacc agttcgcgac ctttacagcg
    25201 aataaaacta ttttatgaaa caacagaggg tgtgaaagag acgttcggcc ttgagcgatg
    25261 acaaaattgc ttcttattgc cgataggctg tctcttgaac accatttacc aagaggtcgt
    25321 gagcctaccg tttaactctg agttacaagg aacaatttca aaaaacagct tctcatgttt
    25381 gatgactatt gtgacttgtg accgaggagt tggcaggaga acaccgttta ttcagaaata
    25441 ggagctacga caaaagtctt gtcatagctc ctattttttg tcattcattt ttcaagcggt
    25501 agaaatagcc tttttgagct aacagttttt cgtaagtacc tatttcaacg atttttcctt
    25561 catcgatcac aacgatttta tctgcctctt tgatcgttga aagccgatga gccacaataa
    25621 aagtagtggg tgtttctgtc aggtaattca gggcttgctg gatttttttc tctgactggt
    25681 tatctaaagc tgaggttgct tcatctagca aaatgatttt tggctgacgt atcaacgctc
    25741 gtgcaatgga gatacgttgc ttttggccac cagacagctt gttgccatgt tcgcctacta
    25801 aggtatccag accatcagga agctggtcaa tcagtgaaga aagttgcgca gcttcgatga
    25861 cttcatctaa acgttctttt gatacgtttt tcaagccata agtgatgttc tctttgatcg
    25921 aagcggagaa caacaaagtg gtttgaggaa caacggctaa ataatttcgc acacttcgca
    25981 tatccagttc atccaaaggc tgatcatcta gaaaaatttt tcctgaagtc ggctggataa
    26041 atccaatcaa taagttaagg agtgtagatt ttccagagcc agatggccca acaaaagcaa
    26101 ttgtttctcc agctttcacc tctagagaaa aatgatcgat aatcggtttg agtgagtccg
    26161 gataaagaaa agaaacatcc tcaaaacgaa aatttccatc caaatgttgg atttttttct
    26221 taccgtgata agtttctaca tcgccagcaa tcaacagttc gccaatagaa gtgatagatt
    26281 ccatgccttt tgaaatcgta ggaatcagcg tgatcattcc agaaacggaa ttgacgatcg
    26341 tcgtgaaata cgtctgatac atcacgacat cgccgggttg gatgcgccct tgtaaagcta
    26401 atatcccagt gaaaatcaaa caaatcagct gaaatatctg aaaactagcc cagctgactg
    26461 atccgaaaac agattgcagg atatctaagt ggaatccttt ttcatagatt tgagtaaaat
    26521 gcttatttaa gcgagttgtt tcgtgttttt ctaacccatg agctcgagca atcggtgcta
    26581 attcgatcac ttcgatcact tttgcagaag tctcttccat ttcttgcctg aagtctgagt
    26641 tggactgtct gatcctttta cggaaaaaga gagtaacgaa tgcggcgaga ggaacagtca
    26701 ataagaaaaa catgaaaaca acaggacttt tataaagcgt gatacctaaa gctacgaata
    26761 aattgacagc gatatttaat ccgctgacaa atacttgaga ggacaacgtt tggatagctt
    26821 ctacatcacg gatgatcttt gactggattc gtccagattg caattctttt tgataaggaa
    26881 tagatagttc ttggattttc ttgataaggg tcgctcttag tccagcttct acttgacgga
    26941 tcgaagtgct atggtatttt acatgaaaat aattcgtcaa tatattttga ccaatcagac
    27001 aagccatcaa aaaagcgttg aaataaatgg cctgcaactg agaagaatct ttcgatgaag
    27061 ctgcattgat tacattggca atagcgatcg gcattaacca agatggaaga tgtttgataa
    27121 taaaaaagag tcctgacatg gcaaaacgcc aataatttcc ctgataaaga tgcagcaatg
    27181 tctgaaaagc atttgcatga tatttttgat aacttttctg tattcgttcc tccataatct
    27241 tctccttaac aatcttggta aataaactgc aagtgttcta ttgcttcagg aacataaatc
    27301 tcaggagtag cttcaagagt ggcgtacatt agaggacgct catatttgat ataatgcagt
    27361 accgggcgga aatctaaaca gcccttgcca acaggtacca tgcggatctt tccattttcc
    27421 atgatatagt ctttgagatg aagcgctgta atataaccat gtaaattgtc caaggcacct
    27481 cggatcactt tttcctgatc agcatgattt tctttatgca tcaaattcgc acaatctaaa
    27541 atgattttta aatttggtga agctacttca tcgattaaac gtttagctaa ctgatagtta
    27601 tagattggat gattgatccc tgcttcaaca gcaacagtta cgccaaaatt ttctgcatga
    27661 gcgactaatt caatgataga atttctggcg atctgataag cttcttcagt aaaattttct
    27721 tttgtgtaac cgacagagac actaccggtt tccgtagcaa tcatcttggc ttgataggca
    27781 gagcacagag caatttgctg tttgaaagtt gccaatgctt gtgcacgaac ttcttgattt
    27841 ttgctggata ggttgatata gcatcctaaa atggaaagtt cgatattgtt tttttggaag
    27901 tattcaccaa aataggcagc actcccaagt gtcatgtcag ttaatttaag ttgttcagga
    27961 aatgcttttt gtggtgcaaa ttggatatgg gacaagtgaa gctgtgatac tttttgaacg
    28021 atttcttcac gatttcgaac atctaaatcg tgggcacgga tgcctaaatt taatggaaac
    28081 atctcaaact cctttttgta aataattagc aagaggcaga cgggattctt ttatcaattc
    28141 aacaattatt cgggcaactt tatcagcgcc ttctggacta aagtgggtat tgtcttttag
    28201 tccttctggg taatttttac aagtatcagg tataagatgc aggtagaatt tttttgtctc
    28261 ttcttttgag aaggtctgga acaattcttg tgatcttgag aacacatcta aaagaggaat
    28321 atggtgtttc tcagcaaatg cacgcatcgc ttttggatag tctccaagta tatctggatt
    28381 caatgttccg ttttctaagt aatctcgtcg cgtcacagat gtcagtaaga ccatttggac
    28441 gttcgctttt tttgcgcatt caaaaaatat ctgcagattt tttaaatagc taccgaaggg
    28501 aagcgtacct ctttcttctt ggattttctg gtcgttatgt ccaaattgta caaataagaa
    28561 atcattcggc tgaaactgtg aagctagacg ggctaacctt ccttcctgga taaatgattt
    28621 ggtgctgcgt ccattctttg cttggttatt gatctggatc tcgggtgaaa aataagcaga
    28681 gattttttct ccccaacctg tctcgggacg cttgttttca tctttttctg ccgcagtaga
    28741 atcaccggca atatggatag taggcatgtt atctcttctt tcataaaggt ttataggcaa
    28801 tgaagcagaa cagcaagaga agaagacgga gcaaatttgg tccgtcttct tctctaaaac
    28861 gtggataaac ggattccgtt atttcactat cctgtttttg attcgttact gttactatta
    28921 atcaattagg caaaaaagcc aaagtaattt ttagcatttg tataactaat cgcttgaact
    28981 agacttccta aaagttgttc atcttcaggt gcttctcctc gcatgaccat ttcgcctaaa
    29041 aattcacaaa gaacacgacg gaaatattca tgtctagtgt aggacaggaa acttcttgaa
    29101 tctgtcagca tgccgacaaa attccccaaa gcactaccat cagcaaattg tgtcaattga
    29161 tcgcgcatac cagctcgagt atcgttgtac caccatccag aacctaactg cagttttcca
    29221 ttctgttctt tttggaaaca gcccatcaaa gctaaaatcg caggatagtc attcggattc
    29281 aatgaataaa ggatcgtctt tggcaactga tccgtttctt ctgcacggtt caataatttt
    29341 tgcagaggaa tagtcaaaga aagatcattc attccatcat agccggtatc gggccctaat
    29401 ttttccaaca tttgtgtatt acagttacga taagcatgga tgtgcagctg catcgtccaa
    29461 ttatgagaat gatagaagtg ggtcaaatgt atcagtgttt ctgtacgata agcatcgatt
    29521 tcatctgaag ataatagttt gttagctcgt gctttttgaa aaatctcttc taatactgtt
    29581 tcatccgctt ctttatagcg taagatgtct aaagcgtggt cggaaacacg acatccatgt
    29641 tgatggaagt attctatccg ctgccctaag acttctatca gttcttgata ggtggtgatc
    29701 gtttggtcag ctgcttcttc cagtagtgtg acccatgcat taaatccttc tttttcaata
    29761 ttgagtgctt tatctggacg gaatgaaggt agaaccttca aatctggttc ttcatgagca
    29821 agcaactgat gatagtgcaa gtcgtctgcg ggatcatctg ttgtacaaat cacttctaca
    29881 ttcgattttt ttgcgatttc ccgacggcga aaatcaggag ctgccaaaat ttcatttgct
    29941 tgtgtccaaa ttttctctgc attttcttca tttatcaaca agtcaatacc gaagaaacgc
    30001 ttcaattcaa gatgtgacca actgtaaagc ggatttccga taatttttgg tacggtttga
    30061 caccaagcta aaaatttttc aaaatcagaa gcatttcctg tgattttttc ttcaggcacg
    30121 ccgcaagctc gcatcaagcg ccatttgtaa tgatcgcctc ctaaccaagc ttctgtcaga
    30181 ttgctgaaat tgttgttttc gtaaatttct tttggatcta agtgacagtg ataatcaata
    30241 atgggcatgt tttttgcgta ggaatggtaa agctttttcg cccaatcgtc ttttaataaa
    30301 aaatcatcag ataaaaacat aaatcttcct tctttctttt tatactgttt tatgaaaatc
    30361 aaagtgttac tccgttttta aaaatggcaa tttctcgaac gtcattttgt tcatttttcg
    30421 tttcttctcc actagctaca gcgatgattt tttgaacaaa cgattctaag attacttcca
    30481 ttggttgttc taataagacg cctgcattaa aatccatcca atgacctttg cgttcaaaaa
    30541 gagttgtatt cgtagatacc ttgaccgttg ggacatatga gccaaacgga gtccctcttc
    30601 ctgtggtaaa caagaccaac tggcaatcgg atgaagcaag agcagaggca gctacaagat
    30661 cattcccggg agcttgcaat aaactaagcc ctggttttct gattttttcg ccatattgta
    30721 gcacatcaac gacaggagag cttcctgatt tttgcgtgca gcctaaagac ttatcttcta
    30781 atgtagtgat cccacctgct ttattaccag gagatgggtt ttcgtaaact ggttccccgt
    30841 aagacaagaa atactgtttg aagtcattga tcaagtcaac gattgagtca aaaacttctt
    30901 cattttccgc tcgtgccatc aatacttgtt ctgcgccaaa catttctggc acttctgtta
    30961 agatcgtgct gcctccttga gcaatcaagt agtcagaaaa tgcaccaagt aaaggattag
    31021 cagttattcc cgatagacca tcagaaccgc cgcatttcaa accgacattc aacttagaga
    31081 gcgggactga tatgcgctgg tcattttccg ccgctgttaa aagctcttct aatagagcca
    31141 caccttgttc gatctcatcg taaacatctt gagccactag aaatttcact cgttcttcat
    31201 catattcacc taaaattttt ttgaattcag gaactgtatt gttctcacaa cctaatccaa
    31261 atactaaaac tcctccggca ttgggatgat ttactgcgtc cgctaaaatt tctcgagtat
    31321 tttgatgatc ttttccaagc tgcgaacagc cataaggatg ctttaaaatc gtaatatggt
    31381 caaactgtcc cagatctgga tgtttttcct tgaactgttt gacgatcagt tcagcaatgc
    31441 cattcacaca cccaacggta ggtactaaaa acaaatcatt acgaatccct acttttccat
    31501 tttttcgcaa gtaaccttga aatgttcggt tctcaaaaag gtaatgactt ggatggacat
    31561 ctttttcata tcgataatcc aattcaccag aaagattggt ttttacatta tgagtgtgca
    31621 gccattgacc ggcagttacg tctgtcgtca catgaccgat tggatagcca tatttgatca
    31681 cgttgtctcc agctttcaaa tcacccaatg caatcttatg accttgcggg atatcttcaa
    31741 gagtggtgat cgtttgctga tcaatcgtca gttgtgtttg ttttggaata ggggttaatg
    31801 cgacgaccac actgtctcgt cgatttaatt tcattgttgg ttgcagggtt tcaagcatgg
    31861 accatcgttc ctttcatttc ttgtaatact gaccggacac ctttttgatc gatctttgca
    31921 gctatttctt gaactgtatc tgtcacattc ggtatttgag acaaatcttc tccccaaagc
    31981 gcagcgtttt gcaataatcg aggaatagct gttccattat cagaccaagc atcagtaaat
    32041 tcgcttatcg tcttttcatc atcatgtggc tttacttgat cgcctcgata cataagaagt
    32101 agcgcagcta gtgaaacagt gattaacggt ggtacctgat tttgttcttc gatatacttc
    32161 ttgaacactg gaagcagacg ggtgctgaac tttgaaacac tatttaatga aatcgcttct
    32221 aatttgtgat gggcaaaagg attcaagaaa cgttctttga tttggtcagc ataaatggct
    32281 aattcatctt taggtaaaga aagcatagga atcaattcta gattgaataa ctgatcaaca
    32341 tatgcggaga ataaaggatc tttcattact tcttctacag tttccaattc cgccaacaaa
    32401 gcaagaggga ccatcgctgt atgcggtcca ttaagcaaat gcaccttacg ttcacgataa
    32461 ggagtcatat catctgtgat gatgacattc aagccagcct gtttgaatgg tagttgattc
    32521 tccaattctt taggcccttc gatcacccaa agcatgaatg gttctgcttt gaccatcaat
    32581 tgatcttcat agttatgccg ttgattgaaa acacctgcat cttcgcgagg ataacctggg
    32641 acgatgcgat caactaaact acaacagaaa acattttctt tttctaacca ctcaacaaaa
    32701 gcaggttcta aatcccattt ttctgcgtag cgtaaaatga tttcttttag acgttcgccg
    32761 tttctgtcaa tcagttcgca aggaatgatg gtaaagccag ctttgtttaa tttgaaacgt
    32821 cggtataaaa aggctgtcag tttgcccggg aagctctgtg ggggagtatc tgttaaatta
    32881 tcagtctcca cgaattggat tcctgcctct gttgtattgg agacgatata ggccaagtcg
    32941 tcattttctg ctagagatag ataagcatcc cattcatcat aaggattgat catttgttct
    33001 actacggtga taatctcgga agtatcaacg atttcgccat tgctgagtcc ttgtaaaatg
    33061 accgtatata aattatcttg ctggttcatc atatttccaa gaccttgttc taaaggttga
    33121 atgattgcaa cattaccttt aaacaattgt tggttattca gctgctgaat ctgccaatca
    33181 ataaatccac gcataaaatt gccttcacca aactgaagaa cttttacagg tgcttcgttt
    33241 tttttcacta attcttttgt cagttttttc atataaactt cctttctgtg ttatgcacac
    33301 gttaacattt ttatataaaa ttacttgtag tttacaagta attgatcgac tcacgaagga
    33361 tcaacaaggt ggagagctca attttagatt gttcgatcgt cctgccttcg atcaaatcta
    33421 gtaaaagctt tgttccttct tgacacattt ctttcaaagg cttacgtacg gtggtaagcg
    33481 gcggattgag ataggagacg actggagaat catcgaaccc gatcagagaa atgttctggg
    33541 gaacacggag gccagctaaa tgtacagctc tcaatgcacc aatcgctatg tcgtcgttgc
    33601 cgcaaaaaac cagagtaggc aggtcagaaa gtgataatag gtattccatg ttttggaggc
    33661 cgctttctaa gctgtaatct cctgttaaaa aataggctgg attgacaggg atgctcgctt
    33721 tttttagact tttcaatacc cctttttccc gttcttttgt cgaacgaaaa tttttctttc
    33781 cgccaatata agcgatcttc gtatgtccgc atccaatacc gtaatctact gcctgcataa
    33841 caccggccgc atcatcggca gtgacgttga taaccgctgg atcattgatg tgacgattga
    33901 caacaacgaa aggaaattct ttttctttga gatagtcgat gaaaggctga tcatcatcac
    33961 tttgactcat aacgatcagt ccatcgtagc gttgcaggtt gatttctgtt aaatcaacaa
    34021 catcgatact ttcaacagat aaactgtaat ttgtgtctaa tactgaatgg atgcctgcaa
    34081 tggaatctgc taggaaattt gatgaagttc ctttatgcaa acttgagaaa aatagtccga
    34141 ttagatattt tttttgattc actaaacctt ttgcactata gtttggcgaa taattcattt
    34201 ccttagctag ttgtcgtatt ttttgttttg tttcattttt tattaaactg ctgttattca
    34261 aagcacgaga aactgtcgta tgagaaacgc cagctgcttt agcgatatct ttgatcgtta
    34321 ccattccatc attttcctta ctttttcact ttttgttaac gcattcatca tattacgata
    34381 actacgataa gtcaatagat ctttgatatg aaaagattgc acacgttaaa aattacttgg
    34441 atttttattt ttaattatgc tattcttgaa agcggggaat gctcatttaa ttagatgagt
    34501 atcaatttta cagaaaaatg aaagcctttt attttaaaag gaggagagga agaaaatgaa
    34561 gaaaagtaca gtattttata aaatattttt accgatgttt ttattaggag ccgtacttgt
    34621 cataggattt agtttattca tttaccagaa tacctatgaa tcgatcgaat cgagttattt
    34681 aacagacaaa aagaatttgc tcaggcaagt taaaactaac gttgaatgga aaattagaac
    34741 gattgaatat tcgttttcta cgtatggttc gaccaaaaat ttctcggaca tattcaagca
    34801 tccgctgaca tatacagatt actccactta ttctgaaatc aggaaagaac taaattttat
    34861 agaaacgatt gttatggatg ataataatta tgatttagtc agtttggctg gtaaatgggg
    34921 agtaatcaat ggatcgttga gtcaactgac cgaagaggaa gttgaaaagt atcaacagaa
    34981 gtacataaat aacaaaaata atttattttg gcaaaagaaa aacaaaggaa tcgaaatggt
    35041 gatttctttg ccaatgtttg aaaaagaaaa atatgcattg ggaattgcta cgatagagaa
    35101 acatacaata gaacaagttg ttggtgaaag tggagaagac atactttcta ttgaaaacga
    35161 agttggcaac ctttttacta ctcagacagt aaaaaataaa gagcaaccaa ctgtattaac
    35221 ggacgtggat ctagattaca atcagctgaa agtgataaga gaaaaagata aaacgtatat
    35281 agtactgaaa tcagattata ataattggat ttacagatta gaagttgact ctagtgcaat
    35341 tggcgcaatg atccgcaatc tgagaatcgg gctagttgca gtgtctttaa cactggtagg
    35401 actcattggt cttctttcct acttattttc ggacagattt gcccgtccga tttctcaaat
    35461 acaggaacgt ctgaatctta aatcaaaagg attcagtggg aaagaactag atttggtcgc
    35521 tcaatcagtc agtcggatca taggagaaaa agaagcgtta agtgcacact tagttaccca
    35581 aaagccacag ctggaaacgc tatttgtact tagtttattt agaaatcgag tagaaaggcg
    35641 agaactagat cagcggttgc agcaatttgg ttatagttct caaaatgact gctattatac
    35701 agctttggtt caaatcgatc tgttagaaga tagtcacggt ggggagcgtg atttgctact
    35761 tttagcgatc aacaacatga tcacggaaat tgtgccaaag gaaaatcgaa tgctgccgat
    35821 cgttttgaat gaagaaatgc aagccactat ttatcgaatg gataaagatg atgcagaagc
    35881 aagcaaaaaa gtcatggagt attgccgact cattcaaaaa cgtgtaaaag aatacttgaa
    35941 tttaactatc agtataggca tcagtaaccg gttcgaaacg ctgaatgaaa gcaagcaatc
    36001 ggttgatcgg gcaaaagaag ccctgtatta tcgtgtaaat actggtccaa gttcaattat
    36061 tttttatcag gaaatcgttc ctgctgctca tgaaaaaaca cttattagat atccgataga
    36121 agaacaaaat cgattgtttg aagccattcg ttctggaaat caggaagtga agaatttagt
    36181 acatgaattg attgatgcat tgtttgcaca aaataaaaat cctttgagtc gggaagtagt
    36241 ttcggtccgc ttgatcaatg aactcgttca attaggacag ttattgggag tagattcaaa
    36301 aaactttgat aacatgaaac aaatttatgt aaaagcactg aacaattatc atcccaaaga
    36361 actagaaaaa cttgttttag aacaattagt tctgccaatc acagaatgct ctcaagcaat
    36421 cactgatcat gaatttaaaa atttgtcgga gaatattatg catatcgtct acacagaata
    36481 tgatcgtgat ctgtctttag atgtgatcgc tgataggttg cattataacc ctaactattt
    36541 aagtaatgta tttaaaaagg aaacaggaga aaaatttggt gattttgttc aaaatcatcg
    36601 tttagaggta gcaaaaaaat ggttgaaaga gactaacctc tccgtaaaag agattgcaga
    36661 aagattgcaa tatcgaaatc cgcaaaattt tattcgtttc tttaaaaaga aggaatcgat
    36721 tacgccggga gaatatcgaa aaaaatattt gtgaatcaag aggctgtttt tcttgtggac
    36781 tgattcaagc aataaaagaa gttagaataa ccctagtatt tgtatttatg gatagttaaa
    36841 tttcaaggct aagcacgcaa aaagaactgt gacaaaagtc ttgtcacagt tcttttttac
    36901 gaataaatgg cgttcaagag acaggctatc gacaataagg cataattttg tgaaatatgg
    36961 gaagctattt ttcaaaatcg cttcttattg ctcctgtggg ttactcgtcg caatgtttgt
    37021 gagagttttt atcatcgctc aaggctgaac gtctctttca caacctctga tacacggtgt
    37081 tccaggagta gattcttcga aaaataagcc gaaatttcac aaaaatttaa gaagcaattt
    37141 tcgtaaatgc cttcttattt cttgaagctg accacttctg acacaactac cattttgcgt
    37201 tcagtacata atcacccttt gacagaacct acgagtgctc ctttgacaaa atatttctga
    37261 acaaaaggat aaacaatcag cataggcact gttgcaataa cgataacagc cattttaact
    37321 gtttgtgctg gtggaatcac atcaacggca ctactttctg cttgcatccc acttgataca
    37381 atgacgattt ggcgtaaaag aatctgtatc ggccatttag atgaatcgtt gatatacaaa
    37441 atagcagtca tataagtgtt ccagtaagta acagcataaa aaagcgagat agtagcaata
    37501 gacggtaacg ctaatggcag cataattttg aaaaatacac caaaatctgt gcaaccatcc
    37561 atttttgctg attcttccaa actatccggc aaggcttgga aaaagtttct cataatgatc
    37621 atattcattg cattaacagc cacaggcagg atcatggccc agtaagaatt gaccagccct
    37681 agagaacgaa caactaagaa cgttggaatc atccccccgc tgaacaacat agaaaataca
    37741 acaagaaagt tgacgaaacc tcgaccaaac aaatactttc tggaaagacc gtaggccatc
    37801 agtgaagttg cacacatact gacgatcgtt ccgacacctg taacaccaat cgaaacagca
    37861 agtgctctaa aaatggtcgg cgtagaaaga atgtagcgat acgcgtctaa agaaaaggta
    37921 gtaggaaaaa ggataaactt tttcgcgacg acttcttgtg tagaagcaaa agatgtagcg
    37981 atgatattta aaaaaggaac gatacagatc aaagctagca aaattagaaa cgtattgttg
    38041 aaaagtgtaa aacttctttc tcctatagag actttctttt tcatatagat aggctcctcc
    38101 tcaaaataaa ttaaatgttt ctgtttctat atgttcaatt tatcatcggt gaaagattac
    38161 gtatataatc atttcctatg ctaagtgtca gatagaaaaa aatagaaggt ttgctatgcg
    38221 tagtttattt gtgaaaaaat acactttatc gttttgtata gcacaaaaat cattgctatg
    38281 taagcgtttt tacttacggt aaaaatgatt atatacgtaa ttcagatagt tatctatcat
    38341 gaagtcataa gcagcaaaca ttcacaaaac taaggagggg cttatggaaa gtgtaaagaa
    38401 acaagaacca tttcaactga cgctatcgaa aaaagaagaa aagctcagaa gacgaaaaaa
    38461 aataattgca ggaatcaaaa cgaataaatt tttatatgtg atgattctgc cgggagtcct
    38521 ttatttcttg atttttaggt atcttcctat ggggggactc gttattgctt ttcaagatta
    38581 tcaaccattt ttaggaataa tgggaagtcc ttgggtcggt ttcaaacatt tcattcgttt
    38641 gtttacagaa ccgacattct ttacattatt aagaaatacg ttgatcttgt tcggattaaa
    38701 tatcttcgtg ttttttccga tgccaatcat tttgtcttta ctattaaatg aagtaacgaa
    38761 caaacgattg aaaaacggga ttcaaacgat catttacatc cctcacttca tgtcttgggt
    38821 aatcattgtt tcgattactt atgtattttt gaatgttgac ggaggggtat tgaatgaatt
    38881 ccttgcaaca atgggatttg aaaaaatcag ttttctaaca tcccctgaat ggacacgcac
    38941 agtatatatc ggacaagtga tctggaaaga gttgggctgg tctacgatca tctacctttc
    39001 agcgataact gcagtcgata cacagttgta tgaagctgca gaaatggatg gagcaggacg
    39061 cttacgcaaa acatggcatg ttacattgcc ggcaattcgt ccagtaatca ttaccttgct
    39121 gattctaaaa atcggtcaga cattagactt agggttcgag catatgtact tgttattgaa
    39181 ttcattgaat cgaagcgttg cagaaatttt cgacacctat atttatacag ctggattgaa
    39241 gaatggacag ttaagtttca gtacagcaat gggattgttt aaaggggtcg taggattgtt
    39301 tatggtaatt ttagctaata agattgccaa aaagctagga gaagacggcg tttactaaga
    39361 tagaaagaga gggaaagata tgctgcagtc attagataaa ataaacggaa ggctaaatcg
    39421 tattttacag ttggtttatt tgaattttct gtggggcggt ttagtcatcg caggtttggg
    39481 agtttttact ttcggtcctg catcgtatgc gatggttgca gtgattagaa aatggctgcg
    39541 ctcaaaagaa acgtttcctt tgacgaaaac gtacttcaca tattttaaag aaaactatcg
    39601 tgaaaccttg ctgatgagct ggatatatgg cgccatcggg attgttttac ttgtggatct
    39661 ttctttcata cacaattggt atcttaggat cgctttgtat attgctgcgt tcatatatgt
    39721 gctctcagca ctctatattt tcccaatcat ggctcattat gattggaaag gatatttttt
    39781 caaaatgaaa atggcatttt tattcggatt ctcacatctt cattactcat tagtgttgat
    39841 attaagtatg gtagggattt atctgatgat catccaaaca atgccaggtg ttttaacctt
    39901 tatcggtggc agtctcttct tttccgcagt cacgtggaca gcaaattcta tattttgcca
    39961 tttggaatgg aagaactcat atacagaaaa aacagaagaa aacaaaaata ttattaaaac
    40021 agtgaaggag aaaatttatg aaaaaagcaa cgctcgtaaa attaggtctt agttttgcag
    40081 gaattctagc acttgccgca tgcggcagca gttcaagtaa cagttcttca gagacagaag
    40141 atggaaaagc taaaatcact tggttaaata ttttgcatca tgcttcaccg cctacagaca
    40201 cgattgtgaa cttgatcgaa gaaaaaaccg atacggaact gacattcaac tggattcctg
    40261 atgcttcaaa agaagaaaga ttaacaactg cattggcttc tgatgaacta ggagatatcg
    40321 ttacacttca aattgcgatg ttgaaaaact cttctgtccg caatgcgtta aaatcaggcg
    40381 tattctggga tgtatcagaa tatttaaaag actataaaaa tttaagtcaa atttctgaag
    40441 atagaatcga agctgcgagt atcgacggtg ccttgtacgg cgtaccgata caaaaagact
    40501 acgctcgtgc tggcttagtc attcgaaaag actggttgga taatctagga ctagatgttc
    40561 caactaccat ggatgagctt tatgaagtag ctaaacaatt tacagaaaac gatcctgatg
    40621 gaaatggtgt ggacgacaca gttggttttg gcgatcgtgc gcctagtgat attcgttata
    40681 ccagctttaa acttttcact tcttattttg gagcaccaaa tggctgggct gtagacgata
    40741 atggcaaatt cactccagaa tttgatacag aagagtatat gaaagctttg aatttttcaa
    40801 gagatctatt tgagaatggc tatttggcac aagactttgc agttacccaa aagactgatc
    40861 agcaagaaca atttgcacaa ggaagaactg gaatctacac tggaatggtg gatatcaaga
    40921 atctgaagac gatgggtcaa ggtattcaag atgatatgga attagtgcct gtaaacaaga
    40981 tctcagatgg tgaaggcggc ggttatcatg tttggtcaga aggaaatggt attggcggct
    41041 tgctagcatt tcccaaatct caagtaaaag acgaagcaca attgaagaaa ttacttcaat
    41101 ttgttgatga tcttttagaa gaagatgtgt ataaattgat gactggcggt atcgaaggaa
    41161 cgcattatga attgaatgat gatggttcta tcgaatttat cgatatggat ctttggcaac
    41221 aagaggtgca accgttatca agctctcgtc ctagtgaagt gacgttctct ttcaaagata
    41281 cagaccctga aaaagaattc tctaatcaat tgatcaaaga aaatgaagaa tttgctgtaa
    41341 tggatccttc tgtgccattg gattcaccga cgaacaatga agtaggatca gaaattgaaa
    41401 aaatcgtcat tgatgctacg gtgcaataca tcatgggaca gcttgacgaa gatggattca
    41461 aaaaagctgt agaagactgg aaagcacaag gaggcgatcg aatcacacaa gagtacgagg
    41521 aagcatacaa agcagcggca cagtaatata gacgattggg acaaatactt cttggtattt
    41581 gtcccaaatc ctattttaat ttttaaagga gagcaaataa tggaaaactg gtcaaagaaa
    41641 ttagcaaaaa gtatcatgga aagaacacct cgcttatatg aagaaaagtg gtataaagga
    41701 aaatggtctt atgactatgg cgtcgtactt aaagggttcc aattactttg ggaacgaacc
    41761 caagaaaaaa tttattttga tttcataaaa gacaatatcg actatttcgt gcaagaagat
    41821 ggaacgatcc gtggctacag cgttgaagaa tacaatatcg accatgtaaa tacaggaaag
    41881 cttttctttt tattgtacaa agaaacaggc gaagaaaaat ataaaaaagc agcagaactc
    41941 ctttcccagc agttggcaaa ccatccacgc acatccgaag gagctttttg gcataaagaa
    42001 atttatcctt atcaaatttg gttggatggc ttatatatgg gttctccttt ttatgctgaa
    42061 tttatccaga attttagtga agaaaaagat taccaagatg ttttgagaca gtttgaaatc
    42121 agttataaac atctattcga tccaaaaaca aatttgctga ttcatgcatg ggatgaaaag
    42181 aaggtccaac catgggctga tccaaaaaca ggtctatccc atcatttttg gagccgatcg
    42241 attggctggt atttgatggc tgcagcagat acctatgaat tacttcatga agaaacagat
    42301 tgttctttgc tgaaagaaat tctagaaaag acactggctg cattacttcc atatcaagaa
    42361 gaaaacagcg ggacatggta tcaagtaaca acagaaacaa aacggaaagg aaattatctg
    42421 gaagcttccg gcagtagtat gtttgtttac gcaatggcta aaggaatacg tttgggactg
    42481 ctgaacaaag aagaatggct tccacaagtg aagaaatcac atcaaggatt acttgatgaa
    42541 tttgttctgg aaacaaaaga aggctggctg aacttgaata aaaactgtca agtagcaggg
    42601 ttaggcggag cagatcagcg agatggttca tatgcttact acatcagtga accaattatt
    42661 tgtaatgatc aaaaaggcgt tggtgcattc ttgcaagcat tgattgaagt ggaggcatta
    42721 taaatatgta tgatattttg acatttggcg catcaattga tgaattgaat actgaagcaa
    42781 tacaacaagc cattgatgct gcagcaagtg acggaggcgg gaccgtagtt gttccagcag
    42841 gtgaatttct aacaggagct ttatttttaa aaagcaatgt cgaacttcat ttaagcgcag
    42901 gagcggttct gaaattctct gacgatccaa aagattatcc tgttgttcat tcacgttggg
    42961 aaggagtcca tcgaaaagtt tatgcttcct gtatctatgc tcaaaatgta gagaacatct
    43021 ctgtcactgg tttcggtaca ttagatggaa atggaaaaaa atggtggcat acttttagaa
    43081 atgaaccaga taatctcgct tatcctcgtc ctaaattgat gagtttccat aactgtcatc
    43141 gaattactgt gaaagatatt aaattgatcc agtcaccaag ttggacgatc aacccgattc
    43201 tttgcagtaa tgcaacgttt gataacttga cgatcttgaa cccagcggat tcaccaaata
    43261 cagacggaat tgatccagaa tcatgcaaaa atgtgcgtat tagtaattgc catattgacg
    43321 tgggagatga ctgtattgca atcaaggcag ggactgaaga tacgtacgaa aggatcgctt
    43381 gcgaaaatat cacgatcaca aattgcacga tggtccatgg acatggcggt gtcgtattag
    43441 gaagtgaaat gagtggtagt attcgtaata ttaccatttc aaattgtatc ttccaagaaa
    43501 ctgatcgagg aatacgattg aaatctagac gaggtcgagg cgggatcgtt gaagatattc
    43561 gagtatccaa tatagtcatg gataatgtga tgtgtccatt tatactgaat ctttattatt
    43621 tctgtggtcc gcgagggaaa gaaccgtatg tatgggaaaa aaaggcttat ccgatagatg
    43681 aacggacacc agcattcaga aggatccatt tttcgaatat cacggcaagg aatgtccatg
    43741 cttctgcagg ttttatttat ggattagcgg aacaattcat acaagaaatc acatttgaca
    43801 atatcgatgt ctcgatggcc caagatgcag ttcccggtgt tcctgctatg atgacaggaa
    43861 tagaggaaat gagcagacaa ggattttata ttggctttgc gggtaaggtt tcctttaacc
    43921 agatgtcgat tgaaaatcac gagggaccag catttctatt agaaaatact aaagaaatca
    43981 gtattgagaa attccaatca aatcaatcag aaaatatgga tgaactggtt gttcgtaaaa
    44041 actttgctta tgcagttgaa tgatttttta ggtgctccat ctagcagaca tacccctagt
    44101 ggaaaacgat tataccgaga aaaacaaaac ggttttatgc ttgaatacta tcaattgtac
    44161 ttaaatgaat tggaaacagt accagccctc tatgcttatc cagaaaaaga aggaccgttt
    44221 ccgccggtcc tttacctgca ttctcacggc ggagattttt cagtcgggaa aagtgaattg
    44281 atccatggtg ctccttactt agcttctcca tcttttgcag aagtactgac aggaatggga
    44341 tatgctgttt ggtcgattga tgcttgggga tttgaagaac gcggaggtat ttctgaaagc
    44401 gagttgttca aacaattttt attaacagga aaaacgttat ggggaatgcg tatttatgat
    44461 gtgatcagct tgatcgatta tttggagaca agggaagaca cagatactca acggctcgca
    44521 acgattggtc tttctatggg aggcttatta agctggtggg tgacagcatt ggattctcgt
    44581 gtcaaagttt gtattgatct agcggcacag gtggacatcg aaatactttt gctacatcgc
    44641 cgcctagatc atcatgggtt ttattactat gtgccaaatc tattgacagc ttatacaacg
    44701 ttagcaatcc aagaaaaaat cgctccgcgc cctcgtctta gcttagttgg aaaaaacgat
    44761 acgatgtgct tggacgaagg cgtactgaag ctgagaaaag ggctggacaa aaagtatcaa
    44821 tcaatgggta gtccagaaaa cttttcttct ttttctttaa caggcggtca tatggaaaca
    44881 caagaaatga gaaatatttg gaaacaattc ataagggagc atttatgagg atgaaagaca
    44941 aactgataat tggaaagaat gctatagata ccccgacgga ttttgaaact atccaagaag
    45001 gaatcgatta tttggcaggc ctgccggata gccatccaaa ggtcttgata gtaaaagaag
    45061 gaagatatga tgaatatata gaaagcagat tatccaattt taaacttgtg ggagcaggaa
    45121 cagtagttat ctccggtaat cgttttgcaa aacaggagta tcttgacggt agccagttag
    45181 ggactttccg aagtgctact tttttcttag aaggatcgaa tgtcgtatta gaaaatcttc
    45241 acatcgaaaa tacagcaggt ccaggagaaa aggtaggaca ggctgttgct ttattcaatt
    45301 caggagatcg cgtatcttta aaaaactgtc gactatctgg ttatcaggat accttatgca
    45361 cgggtccgtt gcctgatttg caaaaagatg gtactccttt ttgtacaccg gcttctgcca
    45421 atcctgagta ttgtcgtcag acctatgaat attgctggat tgaaggaacg gtggatttca
    45481 tatttggtgg ggcagatgcc gtttttcatc agtgtcatat ccatagctta gccagtaaaa
    45541 atcctggata catcacagca gcatctacgc cgaaaaatca aaaaacaggg tatcgttttg
    45601 aaagctgtac cttgactgca gaacctgata ctagaaacgt ctatttagga agaccgtggc
    45661 gtccgtatgc aaatgtctta tttgaagcgt gtaagatagg tgggcatgtt cacccaactg
    45721 gttgggataa ttgggatgac aagaaaaatg aacagactgt caaattctct gaacgtaata
    45781 acaattatga aacatcgatc aaaagacctg aatggataca tttagaaaag cagggggttc
    45841 agaaatgaaa agaaaatggg aactattgct aggaatggtc ggtggcagtc tatctttgat
    45901 tttctttggc gggttagcag ttactttaag taatatgtct gcgtcagagt ttaaaaaaag
    45961 ttatcagtcg cttgctgtag atcattcaac tttgtcttta gaaaatacat ttggattatt
    46021 acaggacatg actggtctgt ttgccgttgt gttgtttatt tcacttgctt ttttagcagt
    46081 agcattgttt ttgactgcta aaggaaaata cttaacaact gccactggtt tgtattttat
    46141 aacaggattc atattgttga ttggcactca gtttattgcg tttccttttg cattttttta
    46201 tttcgcagct ggggcattca gtttatatcg agtaagaatg agaaaaggag cctgaatcat
    46261 gcagactatc aaagtgaaaa atcctatttt aagaggattc aatccagatc ctaatatatt
    46321 aagagtgaaa gagcggtatt acattattgt ctcctctttt gaatggcttc caggaatccg
    46381 agtatatgag tcgaaaaatt tagtcaactg gtcacataca acggatattt tgaccactca
    46441 agtatctttg caaggaaatc ctacaaatgg aagtatatgg gcgccacaaa tcagttatgc
    46501 tgatggattg ttttatcttg tttacacaga tgtcaaaagt gcaggccgtc cgtttaaaga
    46561 tgtccacaat tatttgatca ctgcatctga gatcacaggt ccttggtccg aaccaattta
    46621 tttaaatagt aacggctttg atccttcttt gttccatgat cttgaaacgg gaaaaaaatg
    46681 gcttgtcaat gaactatggg attatcgtct ggacacaccg aataaatcca gcggtatcgt
    46741 attacaagaa tatgatgcag agaagaagaa gcttgatggt cccatctata aaatatttgc
    46801 aggtacagaa ttagcgaaaa cggaggcacc acatttgtat tttcgtaacg ggtattatta
    46861 tttgatgacg gcagaaggcg gtacaggaag aggacattca gttacagttt gccgagcaaa
    46921 gaatattact ggtccttacg agcttgatcc tggttttcct atgctgacag ctagtgacaa
    46981 acctgcttct acattgcaat gtacaggaca tgggagctta gtacaaaccc cgtcaggaag
    47041 atggtacatg acatatcttt gtaccagacc attaaacggt gcggctattt tgggaagaga
    47101 aaccgctatt caagaagtgt attggacgtc cgacgattgg ttaagactta aagatagcca
    47161 gacaactccg atggaagaaa taatgattga gacaaatgaa gaggtacaac aagaaaaaga
    47221 tcatcagttt atggatacat ttgaaggaga gctaaagaag aactggaatg ccagacgcat
    47281 tttgccaaat gctgattggt gtgatacaaa atgtagacca ggttttttac gtctgatttc
    47341 cggtgaatct cttcaatcta ccttcgaaca tcatttgtta gctattcggc aaacggattt
    47401 tacttttgat gcggagacag catttgaata catgcctaat aattttaatc agatggctgg
    47461 actggtactg tacttaaatg aatccaatta tatttattgt tatgttactt ggaatgagga
    47521 caagggaaaa tgcctacgta tgatagaatc agaaaacgga gtagcacaaa tagaagattg
    47581 gacgattcca ctcacagaaa agaagacttt tttgaaagtc actgtaaaga aagagacagc
    47641 acagtttcat ttgaaagacg tatcaactga agaatggaag aaagtaggtc cgcaaaaaaa
    47701 catgtgtata ctctcaggag ggtttactgg aaattttatc gggatagcag tgcatgatct
    47761 aaataaaaaa agaggaagtt atgctgattt tgagtttttc aagtatgatg gaaaagatca
    47821 tctgtaattt aattctttaa taaatgaggt tcactaactt attttcacta gttagtgaat
    47881 ttttttgttt gtatatattg ttatgtaaaa aaagttatca atcttatgca tcaatgtttt
    47941 tagattattt tttgtttttt atctgtcaag ataatgcaat aaaaagccaa cattgtgaat
    48001 ataaaaacaa gaaaaaaaga gttataattt tgaaaacgtt tactagaaga ggtaggagga
    48061 attcaaatgc tttcacaaaa tgctgttaca gcaaatacaa taaaaaaaga aaaaaaggaa
    48121 tttgggattt ccgataagat aggctacatg ttcggtgatc taggtaactg ttttatttta
    48181 ggtttagtca atagtttctt gatgatttat tatacgaatg ttcttggcgt ttcaggggca
    48241 atcgtaggta cgttattctt gatttcgaga attttggatg cgtttgctga tgtgatggtt
    48301 ggaagattat gtgatgtctc agagttaaca gaaactggcc gatttattcc ttggatcaga
    48361 aaaatgaagt atccattttg cttagtgact gtcattttgt ttttgccatt cgtccaacat
    48421 cttccaatga cggtgaagat tgcttatatt tttgtttcat acattgttta tgggattttt
    48481 ctctcaacaa tcaatatccc gtatggagca atggcagcag caattagctc aaatcctaat
    48541 gaccgcacct cgttgtccac gttccgaagc attggttctg cgattggcgg atcaactaca
    48601 ggattcttca ttccgatttt aatgtatacc cataacaaga gtggacaaca agtcgtttca
    48661 gggaatcatt tcttttggat ttcaatcgga tgtgctgcaa tagcatttgt cgcatatatg
    48721 ttaacttgta aattgactac tgaaagagta agagttgtca aaaacgaaaa agtatctgct
    48781 tctcagttgg taaaaggttt gttagctaat cgagcactga ttattttagt cattgttgac
    48841 attttcattg tgatcaatca gattttagct gggacgaata tgacttattt attcaatgat
    48901 tacttccata ataaacaagc aatgtctgtt gctcttttat ttacttacgg aacagtagta
    48961 gttttagcac catttgctac aaagctgaca aaattatttg gtaaaaagga agcaagcgta
    49021 tttgcgttac ttgcttcttc atgtatgtac ttgctgatgt atttccttca tataacaaat
    49081 gcatgggtat atctgattct tttatttatc gctactttag gatctggttt attcaatttg
    49141 atggtctggg cattcattac tgacgtgatt gattatcatc aatataagac aggcttaaga
    49201 gaagatggaa cagtatatgg agtaaattct tttgcgagaa aagtaggaca agcatgtgca
    49261 ggagcggtag gcggatttat gctggcactc attggttacc aatcgtctac aacaggtgga
    49321 gccatccaat cagttttagt acaagaaagg atttatacga tggcaaactt gttaccagca
    49381 ttctgcttat ttgtatccgc aatcattttg ctagtaggtt acccactgaa tcgttcaaaa
    49441 actgtattta ttggtgaaga attgaaaaaa atcaatgaaa gatagggaga aacgtattgc
    49501 ggacaaaaaa agggattatc aatgctttga actttaaaac aaacgacact caacaagatg
    49561 atacaataat actgcaaaaa gcaatcgatc aaggtgcgaa agaacactta cctgtattta
    49621 ttccaaaagg catttattta gtcggagccc tttttttaaa agataagagt catcttatct
    49681 ttgaagaagg tgcagtcctc aaggggagaa cagatatcga agcatttcca gaaatcgata
    49741 cacgagtagc cggcgtagaa atgaaatggc cagcagcgat tttgaatgtt ctctcggcga
    49801 aagatattct tatagaagga aaaggaataa tcgacggtca aggagaccat tggtgggagc
    49861 tgtattgggg aaaagatcaa aaaagcggga caagagctga atacgatcaa aagggacttc
    49921 gttggattgc ggattatgct attaaacgtc cacgcgcttg tttactgtat catgcagaac
    49981 atgttgttgt tcgtgatttg atttttcaga aatcaggttt ttggaacttg caaatcactt
    50041 attctaacga tgtattagta gaaaaagtaa tcatccgcaa caatgatgga ccaagtacag
    50101 atgggattga tattgattct tcaacaaatg tgcgtgtcta tgaatgtgat ttggcctgtg
    50161 gtgatgattg tattgctatt aagtctggca gagatggcaa tggtgcaaga gtcaatcgaa
    50221 aatcatcaag aatcgaggtt gctagatgta aaatccgttc aggatacggt gtaactattg
    50281 gtagcgaagt tagtgctgga gttagtgacg tatatattca cgatatcgat ttttttcagt
    50341 cagactgtgg tattcgaatg aaatcttcaa aagaaagagg gggagtgatc gaaaatatca
    50401 gggtagaaaa tctgaatatg attgatgtac aatttccttt ttcttggata atggactggc
    50461 ataatgaata caatagaaaa aatagcaatg accttgctca aatgccagaa agttggcaag
    50521 cagtggctga agaaatacct gaatcaaagc aaatgacgaa agtcaaagac atacacatca
    50581 aaaacgtaca ggcatgcctt tctccaggtt actcacttcc ttcccgagct tttgatttag
    50641 tagcatttcc tgaaaagcct atagaagatg tctgcttttc tcattgccaa ataactgcaa
    50701 aagaattcgg gcgaatcgaa gcagtacaaa acttatgttt caaaagctgt gatttatcta
    50761 tagaaactgg caacacagct gcaaacaata cttttgacaa tcgttgaaat tataataagg
    50821 tcaagcttaa ataatatttt agcttgacct ttattttttt taatgatata ttaaacaacg
    50881 ttgtcgcgct tcattgaaac attttatgaa aattccaaaa aagagttgac acatgttttt
    50941 agacgtgata agataactaa gtcgttaaaa agaaccactt gcgaagcttg attctatcga
    51001 aaaaaacttc aaaaaagttc ttgacaaata acaaacgata agttatgata aatgagttgc
    51061 tgaaagattt cgaaaaacga aatcgaaaaa aacttttaaa aaagagttga caatcgtttg
    51121 tctctctgat atgatataaa agttgctacg gcagccaaaa atgaatcggg aaacactctc
    51181 gatgaagtag acctttgaaa actgaacaaa gtaagacaaa ccaaatgtgt agggcgtctt
    51241 gattcaattc aagacaa
//
LOCUS       DAFLVO010000011        49372 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.011, whole genome shotgun sequence.
ACCESSION   DAFLVO010000011 DAFLVO010000000
VERSION     DAFLVO010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49372
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.011"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..1087
                     /locus_tag="L1U99_000690"
     CDS             <1..1087
                     /locus_tag="L1U99_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1211258.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1305..2447)
                     /locus_tag="L1U99_000691"
     CDS             complement(1305..2447)
                     /locus_tag="L1U99_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1211259.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2452..2637)
                     /locus_tag="L1U99_000692"
     CDS             complement(2452..2637)
                     /locus_tag="L1U99_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBN1211260.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(2991..3236)
                     /locus_tag="L1U99_000693"
     CDS             complement(2991..3236)
                     /locus_tag="L1U99_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1211261.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3230..3631)
                     /locus_tag="L1U99_000694"
     CDS             complement(3230..3631)
                     /locus_tag="L1U99_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1211262.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(3818..5626)
                     /gene="uidA"
                     /locus_tag="L1U99_000695"
     CDS             complement(3818..5626)
                     /gene="uidA"
                     /locus_tag="L1U99_000695"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HBN1211263.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(5649..7415)
                     /locus_tag="L1U99_000696"
     CDS             complement(5649..7415)
                     /locus_tag="L1U99_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HBN1211264.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(7428..8222)
                     /locus_tag="L1U99_000697"
     CDS             complement(7428..8222)
                     /locus_tag="L1U99_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBN1211265.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(8232..9608)
                     /locus_tag="L1U99_000698"
                     /pseudo
     CDS             complement(8232..9608)
                     /locus_tag="L1U99_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(9728..10375)
                     /locus_tag="L1U99_000699"
     CDS             complement(9728..10375)
                     /locus_tag="L1U99_000699"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HBN1211266.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(10459..11886)
                     /gene="uxaC"
                     /locus_tag="L1U99_000700"
     CDS             complement(10459..11886)
                     /gene="uxaC"
                     /locus_tag="L1U99_000700"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBN1211267.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(11960..13039)
                     /gene="uxuA"
                     /locus_tag="L1U99_000701"
     CDS             complement(11960..13039)
                     /gene="uxuA"
                     /locus_tag="L1U99_000701"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBN1211268.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(13042..14673)
                     /locus_tag="L1U99_000702"
     CDS             complement(13042..14673)
                     /locus_tag="L1U99_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBN1211269.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            14977..15648
                     /locus_tag="L1U99_000703"
     CDS             14977..15648
                     /locus_tag="L1U99_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1211270.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
     gene            complement(16373..16708)
                     /locus_tag="L1U99_000704"
                     /pseudo
     CDS             complement(16373..16708)
                     /locus_tag="L1U99_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(16805..17257)
                     /locus_tag="L1U99_000705"
     CDS             complement(16805..17257)
                     /locus_tag="L1U99_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211271.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(17264..17812)
                     /locus_tag="L1U99_000706"
     CDS             complement(17264..17812)
                     /locus_tag="L1U99_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBN1211272.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            complement(17857..18189)
                     /locus_tag="L1U99_000707"
     CDS             complement(17857..18189)
                     /locus_tag="L1U99_000707"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211273.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(18203..18460)
                     /locus_tag="L1U99_000708"
     CDS             complement(18203..18460)
                     /locus_tag="L1U99_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211274.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(18655..19197)
                     /locus_tag="L1U99_000709"
     CDS             complement(18655..19197)
                     /locus_tag="L1U99_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211275.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VGQEAQKIDAIKIYYVRSAY"
     gene            complement(19218..20309)
                     /locus_tag="L1U99_000710"
     CDS             complement(19218..20309)
                     /locus_tag="L1U99_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBN1211276.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(20317..22527)
                     /locus_tag="L1U99_000711"
     CDS             complement(20317..22527)
                     /locus_tag="L1U99_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211277.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(22543..25071)
                     /locus_tag="L1U99_000712"
     CDS             complement(22543..25071)
                     /locus_tag="L1U99_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1211278.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            complement(25123..25533)
                     /locus_tag="L1U99_000713"
     CDS             complement(25123..25533)
                     /locus_tag="L1U99_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211279.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            complement(25546..25764)
                     /locus_tag="L1U99_000714"
     CDS             complement(25546..25764)
                     /locus_tag="L1U99_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211280.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(25761..26753)
                     /locus_tag="L1U99_000715"
     CDS             complement(25761..26753)
                     /locus_tag="L1U99_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBN1211281.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            complement(26832..27743)
                     /locus_tag="L1U99_000716"
     CDS             complement(26832..27743)
                     /locus_tag="L1U99_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBN1211282.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(27762..28106)
                     /locus_tag="L1U99_000717"
     CDS             complement(27762..28106)
                     /locus_tag="L1U99_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211283.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(28126..28682)
                     /locus_tag="L1U99_000718"
                     /pseudo
     CDS             complement(28126..28682)
                     /locus_tag="L1U99_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(28763..29263)
                     /locus_tag="L1U99_000719"
     CDS             complement(28763..29263)
                     /locus_tag="L1U99_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211284.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            complement(29264..29809)
                     /locus_tag="L1U99_000720"
     CDS             complement(29264..29809)
                     /locus_tag="L1U99_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211285.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(29806..31062)
                     /locus_tag="L1U99_000721"
     CDS             complement(29806..31062)
                     /locus_tag="L1U99_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBN1211286.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            complement(31422..31733)
                     /locus_tag="L1U99_000722"
     CDS             complement(31422..31733)
                     /locus_tag="L1U99_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211287.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            complement(31756..33066)
                     /locus_tag="L1U99_000723"
     CDS             complement(31756..33066)
                     /locus_tag="L1U99_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HBN1211288.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            complement(33680..34132)
                     /locus_tag="L1U99_000724"
     CDS             complement(33680..34132)
                     /locus_tag="L1U99_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211289.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            complement(34134..34499)
                     /locus_tag="L1U99_000725"
     CDS             complement(34134..34499)
                     /locus_tag="L1U99_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211290.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            complement(34598..38881)
                     /locus_tag="L1U99_000726"
     CDS             complement(34598..38881)
                     /locus_tag="L1U99_000726"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HBN1211291.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            complement(39028..39267)
                     /locus_tag="L1U99_000727"
     CDS             complement(39028..39267)
                     /locus_tag="L1U99_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211292.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(39357..39629)
                     /locus_tag="L1U99_000728"
     CDS             complement(39357..39629)
                     /locus_tag="L1U99_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211293.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            complement(39712..39963)
                     /locus_tag="L1U99_000729"
     CDS             complement(39712..39963)
                     /locus_tag="L1U99_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211294.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            complement(40959..41870)
                     /locus_tag="L1U99_000730"
     CDS             complement(40959..41870)
                     /locus_tag="L1U99_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1211295.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            complement(42066..43901)
                     /gene="lepA"
                     /locus_tag="L1U99_000731"
     CDS             complement(42066..43901)
                     /gene="lepA"
                     /locus_tag="L1U99_000731"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBN1211296.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            44048..45268
                     /locus_tag="L1U99_000732"
     CDS             44048..45268
                     /locus_tag="L1U99_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1211297.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            45288..45782
                     /locus_tag="L1U99_000733"
     CDS             45288..45782
                     /locus_tag="L1U99_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBN1211298.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            45760..46446
                     /locus_tag="L1U99_000734"
     CDS             45760..46446
                     /locus_tag="L1U99_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211299.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(46597..49206)
                     /gene="clpB"
                     /locus_tag="L1U99_000735"
     CDS             complement(46597..49206)
                     /gene="clpB"
                     /locus_tag="L1U99_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBN1211300.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
BASE COUNT        14975 a        10149 c         7262 g        16986 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaaccac cggtggcaaa ccggtggcaa atccatgtaa
     1141 acatggttta ttttttacac tgttttcaaa caaacccttg ctatttcttc ggttcgtcct
     1201 cgtccatttt cgataccgac agctagctta taacccaagg tatatcaaca taaaaaaata
     1261 aaaataggct atgacagcag cgtgacagca aaaaagatgg aaagttaaat atcaaacctc
     1321 gtaatttcat ttgcgagtgc ttgatttgtt tctggatata agtgtccata tttgtccaaa
     1381 gtagttttaa tagaggcatg acctagacgc ttagatattg catagatatt tttattatgt
     1441 tcaattaaaa aggcaacatg cgagtgtctt aatccatgca tatgaattgg ttttactcct
     1501 gcaatttcag ctagtttttt tattctgctt aaaatagttc ttggagatgg cggtaatcca
     1561 tcaaaagaaa aaaccaattc tatatttttc ccaattgatt gttgagtttt tttccatgtt
     1621 tttaaatctt caacggtttg tctgtctaac gaaattatcc gaatacttga tgtatttttt
     1681 gtttcagcaa attcataatc ttgtcttgta cggatgtaaa ttgacttatt tacgctacat
     1741 ctgccattta ttaagtcaaa gtctttccat tgtaacgcta agagctcctc actccttaca
     1801 cctgtaacaa aaataaaacg catcaaacgt ttataaaatt cttcataaaa atccccgtga
     1861 taaacactat tatatacttt cttaaattca tcaactgtcc aaaattctac ttgaggacgc
     1921 tgagttttta ttttacctat agtatctaca ggattttctt caataatttc aagtacaatt
     1981 gcccttttaa aaactactct caacttattg aatatctgtt taatataatt tggtgataat
     2041 ggttgctcaa tgcccttttt tacaacatgg attttcgata aaaactgttg aaattcctgt
     2101 atatgaattg gtcgaatctt tacaacctgc atttctccaa aaaaatccaa tgcacgttgt
     2161 aaaatatgat ctgttttcat atatgttttt tctacagttc ccaacttata ccaaggaaaa
     2221 aaatactctc gataaaaatc atgaaacgtt attccttgca gataaattcc ttgtgaatca
     2281 gaaaaacttt gttttaactc ttcgagtccc cttctagctt ctccttgagt tttgaagcct
     2341 cttctggtca cttgaattct ttttccaaag cgatcttgtc ctaaagttgc agaaaaaaac
     2401 caagtgcctc tttttctgtc tttataaaca ttcgcaattt tcctcatttt actattcctc
     2461 ccaagaaata tggagaactt cttctaaaat tgaaatagga attcttttta tttttgaatt
     2521 acgataaaaa aagtatcctt tctcaactaa aagttcttta cattccttga agattttatt
     2581 agcatagtac tgagaaaaac ctagattaat caaatctttt cgagtagctg ttttcattat
     2641 agcaccttcc ttactttttt tcatttattt ctatcagctg cttttgtcaa aagcacatag
     2701 gaatttcacc tctccccaag tttacggcga gccttacgga agtatcatta tcccaacttt
     2761 aaatcatcgc tttttattga ctataaaaat tattttagaa tatttatcgc tccttcttta
     2821 cagcaagaaa tcatggcgca actaaaatat gctccttaaa gtgttaacgt actgatagaa
     2881 tctatttaat tttcaatgaa caataggttt tctacctaaa agaatctact aattccttaa
     2941 ctattagaag attcttttaa acagaaaaag tggaaagggg atttttttaa ttagttaatt
     3001 ttaaatttta agatcgcttc tattaattta atttctagct gacttatcat atattcatct
     3061 acataggtaa cgaattgacc tacctcgtta aatccatttg tcaaacataa cttagccata
     3121 taagaatgat aatgtttgag tatcatcttg atcgaaattg gatctccttc tagagcagat
     3181 aagataatgg atagtggaac taataggtac tgccgctttt tagatttatc taccataggt
     3241 cataccccat tttcaattgt tcaactgcct tctttcgttg ataccagata ccacttgtgc
     3301 tcatattgag aattttaccg atttcagcat cattaaaacc tgcaaaataa taaagtagga
     3361 taatctttct tcttatctcc gataactgat caattgctgc tgataacttt tgatctgaaa
     3421 ttaatatttc cattccaaat aagaaataga catcttgttc atcaaaatga gtttgggaat
     3481 acctgccttc atttgaatct gccaatggtt cctcattatc ctttatgtta gcgtttcgtt
     3541 ttcgaataga cttagcttcg tttcgtaata cttttttaca gtaggcatca aattggtgtt
     3601 gtatagatat gtcattgtaa tgttgttgca tgataatatg ctcctttttc cccctttcca
     3661 ctaatacaac aatcagaaag cccctttttt tcgaaaaaac tagaaaaaaa acataaaaat
     3721 atttatcatt ctttaaacag aaaatctttc tataaaaaac aaaaaaaaac gattaggcta
     3781 ggctaatcgt tttttgaaca ttcttaaaaa atccaaatta ttttttataa ctgaaattgg
     3841 gtattgatga ccatcgtttc tgtagatagt aagcaatcat tttaggtttt ctatctctag
     3901 taaagattcc tttcttattt ccttgcactc ttaaaatccc ttgacttgtt gcaaaatctg
     3961 caaaattcca cacttgttca ccaacaaaat tttcacatgt atctattact tcgtgatttg
     4021 cttcgtaata agccacttga tactcttctg taaacattgt tggtactgta tcatgaaatc
     4081 cagctactgt atctgctcca tattctgtaa acattattgg cgtatcagga catctttcca
     4141 tccatccatc tagctctttt ttcaacagat attttgcatg tgccagatcc cctcccgaaa
     4201 cataccaacc ataataacga tttaaacata aaacatcgac aatatctcct accttacaaa
     4261 catctggcgt tgattttaga taagtaacga ttgttacagg tcttttctgc ggatcaagtt
     4321 ctttagttaa ttcaactaaa ggttcaaaat attctttagc accttcggaa tccgaatctg
     4381 gttcatttgc aatagaccac attacaacac ttgggtggtt cttgtcgcgt tctatcaatt
     4441 ccttgatcac cgttttatga gaattttctg ttcgtatctc tttccacgta ttatgttttt
     4501 ccacattatc atctaataaa gtggccatga aatttaaatg taaccctact gcaggtactt
     4561 catcaataac tacaatacct tctcgatctg ctaatcgcat aatttcttct gagtaaggat
     4621 aatgtgatgt tctaaaagaa ttagcaccta tccatttcat taaattaaaa tctttaatat
     4681 ttacagcctc attcaaacca cgtccattaa catacgaatc ctcatgctta ccaaatcctt
     4741 taaaataaaa aggtttatta ttaatcaaaa atttgccatt ggtaacctga acactgcgaa
     4801 taccaaattc ttctgtatag gtatcgatca ctttattatc atcaattaaa ctaattttca
     4861 tactatataa ataagcgtct agaggttccc aaaaaattgg attcttaagc tgaatcattc
     4921 ctttctttcc ttcagcttca gctacaagtt gagcctcttc gtcatatatc gctattaaga
     4981 tttttccggt ccattctgta tcgatattga attctacact tgcatccaaa tcagttattc
     5041 ttgtattaat agtaatatca cttatatagt ctttcggagt tgtatataac ttaacaggtc
     5101 tatgaatacc tgcataattg aagaaatcaa aattaactaa gttttccttt tttatatccc
     5161 cattttcctg tactgtttcc ttcataatcc ccacaggtaa agtactatcg tcaataatat
     5221 tgtttacagc aactgtaatt cgattattcc cgtcttttac aaaccgatta atttcagact
     5281 caaatggtgt aaacccacct ttgtgttgag taataaactt tccattcaaa aaaacttttg
     5341 cttcatgtgt tgcagatcca aaacgaagaa ctaatctttc ttctaataat cttttaggaa
     5401 gagtcacttc tttttcatac cacacccatc caacatgatt tctaatgttc tctgtttcaa
     5461 ataaatcatt ataagaagag ggaactgaaa tcggataact ctctttttca tttattggtt
     5521 ctaaagcaag ttcttcctgt aagtcatcat ttgtatctaa tttaaatctc cagagaccgc
     5581 ttaagtcaat tacttgcctc gtctctgtca taatgggata caacatataa accactccta
     5641 tctaaatatt aaataaatgt atcctttaaa ccacaataag catctattgg acttactccc
     5701 ttaaattcag aaagacccat tagtttgtcc accaatattt ctaaagtttc ttgttttcca
     5761 tcataagtat taatataagt ctttacttga ggtacatcag ccaaatgaaa cggacactgt
     5821 acagatacaa aaattgttgg aatttcatga atgtaaaacg gtatatccgg agttccttta
     5881 cttgctggcc agacaattcg ttgaactgtg cctggattaa cattagctat attaatgatc
     5941 aagtcatatt ttttagttaa atttttaatt ggtctcttag cagcatatat tccagctata
     6001 tttttaattt tttcttcttg cgataatcct ttcaattctt cttcaggtga aatgtatttt
     6061 tcaacttcaa atccttttgc tgacaaaatc tgtttcaata aatcaatggc ttgaggtcta
     6121 tttccagcaa ctacttcacc aaacccacct tttaccccat gtacatctac tagtaaaatc
     6181 cttttatatt tttctggtac aataggccaa atatcttgtt tatctttaac taatgtaatt
     6241 gcttggtcag ccacctcttt aaaaattgat ttattttcaa ttaaaccaat tttttccaga
     6301 gcttcttgct taggtaataa aatttgttct tttgcttttt tgtgtaatcc caatttagct
     6361 tttaacccta aaattctttt taaggcatct aataaccgat catcagtgat aattccttta
     6421 cgatagcctt ccatcatata attaaagtct tcatctggat cattaaaaaa tagaaataga
     6481 tcacatccag ctgcaataga agtgggcaat aattctgatc gtttcattgc cccagtcatt
     6541 cctaacatat gactagcatc agtaactact aatccattaa atccgagttt tcctctaagt
     6601 aagtcagtga ttaattcttt tgataaagtt gcaggaagta aatcttcatc tttcagatca
     6661 ggattaaaat gttttgaata agctggcata tggatatgac ctgccataat tgaaggtaat
     6721 ccagcttcta ttaagcctga gtatactttt ccaaaagaat tatcccattc ttccgtacct
     6781 aaactattaa tactaaaaga tagatgctga tctcgttcgt caataccgtc accagggaaa
     6841 tgtttagctg caggcaaaat tccactctcc tgaatacctt tcatataagc taaactaagt
     6901 tctaaaactt tatcagggtt ttgtccaaaa gatcgactag aaatgatagg atttctccaa
     6961 tttctattaa tatctacaat aggagcaaaa ctccagttac atccaatagc cgatgcttca
     7021 atcccagaaa ctctccctaa ttcataagca tatttcgcat catttgttgc accaattttt
     7081 acttctacac caacttcagt accatctgta caagctccgt taccacctgc ttccgtatta
     7141 gcagcaatta atagaggaat tttactttct gtttgtaaga tatagttttg atcatatacc
     7201 tcatcagcag ttcctggatt atatcgtaca gctccaatat ggtactgatt gaccatatta
     7261 ctcaagtaat ttttatcacg actagatccc atattaacaa acaattgacc tattttttct
     7321 tccaaagtca tagaatcaat cgtctcttca atccaagaaa tagcatcttc atctaaatta
     7381 tatggttttt ttcgtaaatc tacttttata gtcattttct ttctcctcta cttattagta
     7441 agatttttcc aaaaagtatc tatatatttt tgttcaatat ctacataatc tcccgataaa
     7501 catttaaata aaacatcagt tcttaagttt tcccatgatt ctttttcttt attgaccaaa
     7561 ataggataaa agaaaacttt atttttattt gcagcttcta gatcaccagg agaatcacca
     7621 atcattaata tcttatccaa atcacaacca ttttcaatta cacttcgaat aatatcttct
     7681 ttttttcctt tatcttgaca acacagttca tcaactaatg ataataattc atgtctttcc
     7741 cattcttctt gaacagcttc cttattagct gagcttacaa taattatctt cccatatttt
     7801 ttcagagctt ttatagtatc tctagcactt aaaaagggtt tatctaatcc ttttgcttga
     7861 ctaatctgtt gattgacttc ttccgaccat tttaaagctt ttaataaatc ctctgactga
     7921 gaatattcta tttccctctt caaagatgga ttagacaatt cttttgttag agatacccag
     7981 tgctttaatc gattaatcga tgttacatca tttttttcta atgttttaac taaacctaaa
     8041 aatctgttta ttccacgagt ctctgaatat aaattaatat tattccaatc ctgtaggaat
     8101 ttttctctat gatgaacatc aaaaatctct gcagcaattg gtccgaaaaa gagattgtgt
     8161 ttataagtca tcgtatccat aacacagcca tctgaatcaa tacaaaatat ccaattattc
     8221 atatttctct cctatttatg tttttgtttt aaaagctcgc aattttctaa gactttatct
     8281 ttagataatg gataaaggaa aaataaaatt aatcctacaa tcagaaaaca aattgatgga
     8341 attaatgttg aagcgttata taacttttct aaaacatctc ccgtttgtac atttgctaaa
     8401 gagtcatagc ctataataga aagagtccaa cctccgacgc ctccagctag agcttgacct
     8461 atttttctag caaaagaata taccgcatat acggtcccat cttctctttg atcagacttt
     8521 acttcttgat catcaataac atcagtaata tttgcccaaa taacagtatt aaacacaccc
     8581 aaacccatat agccaaccga actaagaatt aagaatacat acatattact agcttttatc
     8641 aaaaataaga tcaaatatac tattgctgaa aagaacattc ctactgatgc cagttctttt
     8701 tttccatatt ttttacttaa aaacaaagtt aaaggcgaaa caactattaa aaccaaaata
     8761 ggattgataa aattcattaa aactattccc tgtgcatcat tatagtaatc aggaaataca
     8821 taattattca tactcataat taataattga gcaaggagta agaaaatagc cgcaccaatt
     8881 atagaaagta atgccctatt tttaactaac ccttttaaag attttaacaa tgaaactttg
     8941 tattgagatt ggtcaattct tactcgttca gtagttagtt tataacatat taaataacaa
     9001 ataagtgcac atatcgaaaa tattcccgca acaattgtaa aagttgatcc accacgaact
     9061 atttaagcgc ctgaatcatc tcttgtataa ataaataatg gtgttaatac accaatgacc
     9121 aaacttgcta aagtagctcc aacatttcgg aatgtcgata gcattgttct ttcttctgta
     9181 atagaagtaa tagctgatgc cattgatcca taaggaatat ttatagatgt gtaaaaaata
     9241 ctcccccata atatatacgt aacatacatg tatactacct taacgctcat agaagctgaa
     9301 atcatagaag tttgatacat taaaaaactt gctaaagcga ctggaccact cattcttaaa
     9361 atccacggtt taaacttacc ctgcttagtt gctttcgatc tatcaacaat acgccccata
     9421 gttacatcag taactgcatc gataaatctt gctactaaaa ataatgttcc aacggcagct
     9481 ccgcttatcc ccaatacttt tgtataaaag atcattaaaa aagaactagc aaaaatgaaa
     9541 gtaaaatcgt ttccaaaatc tccaaacata tatcctattt tgtctcttat accaaatttt
     9601 ctttccatac aattctctcc cttctgttgt taagcgtttt cattctgatg aaagtacgta
     9661 ctatactctg aagcgtaaag agtcagtatt tattttttac atttcagagt attatttgtt
     9721 ttttctccta ataattcttt atctcataaa acttatctat atatttacta gctactcgac
     9781 ttacttcttc aaaatcacct ttttcaacag aagccaataa attcccacct acaccaactg
     9841 caacaactcc tacttcaaac caatcttcta agttctctat acttactccg ccagtaggca
     9901 ttatatttac gtgtggtaat ggagcttgat aggcttttac aatggatgga ccaaaagcag
     9961 aacctgggaa tagtttaatg atatctacgc cagcagtaag tgcctccttt atctcagtaa
    10021 ttgtcataca acctggtaaa taaggaattt gatataaatt acaaatctca gctgtttgtc
    10081 gatcaaaaga tggactaacg atatattctg ccccagccat aattgcgata cgagcagtaa
    10141 acgcatctaa aaccgtaccg gctccgatta ttacatcttt ttgatcagca tattttttag
    10201 caatttcttt gattatttct tcagcattag gaactgtaaa agttagttca atccctttaa
    10261 ttccacccgc aataattgaa tttattgctt taatggcctc atccttattt ttcccacgta
    10321 caaccgcaat gactccagcc gcttctaact tacttaaaat ttctactttt ttcatatcta
    10381 tctccttcct ttatggatac atactttgtc tagctgtact aacttacaaa gaataaattt
    10441 aagcttttat ttcaagtatt attttctact tccgatttca aaaaaattaa aataattata
    10501 cgcattacga taacaaatat tctccactat ctgactaaga tacatttcat catctggaat
    10561 tcggcctgct ttaacccact cgcttagtaa ttgacataat actcgacgaa aatactcatg
    10621 gcgaggatag cttagaaaac ttcgagaatc agtcaacata cctgtaaaat tcgacaacaa
    10681 actttgttgt gccatcgtag tcaactgttg acgcattcct tcagctgtat cattgaacca
    10741 ccaagcacat cccaattgga ttttttgaat cataccccct tggaagcttt gcattgctgt
    10801 tgctagtgga agccaatcag ttggatttaa tgaatataaa attgtttttg gtaagcaccc
    10861 actcttttca gcggtatcga acaatgctac aacattttgt gtcaaactag cttgatcccc
    10921 catcgaatca ccaccgacat ctactccaat ttgttccttt aatatacttg aattatttct
    10981 taaagcattt aaatgcattt gcatcgtcca accatatctt gtatactcag acatcaaatg
    11041 taattgaata cctgtaacaa attgtgcaat ttctgataaa tggaaatccg tttttcctgc
    11101 taaagctttt attaacagat tgtcgagtat tttttcatct gctatttcat aaaaataagt
    11161 attcaaaccg tgatctgcta atcgacagcc aatttgatga aaatgatcca ctcgttggct
    11221 caatgcttgc ttcaacccat taaagtcttt gattggtata gccgctgttt gactaagttt
    11281 taaaatatag ttcgaaaagc ctgatgattt gatactccag accttatctg gacggaaagt
    11341 aggtaatacc ttgaaagaat tatcctgttt agaaagctca gtatgatacc acaagtcatc
    11401 tgtaggatca tccgttgtac agatggcttt cacatccatc atctccaaca attctttcgg
    11461 gcgataggaa tccgtttgaa ttttttcgtt agcacgtcgc caaatttctg gtgcattctt
    11521 ctcagaaatt gtcaaatcaa tatcaaagta acgttgtaat tccaaatgag accattcaaa
    11581 aataggatta cctggcgcct tctccactgt ttttacaaaa gctaaaaatt tttcataatc
    11641 atcacctgga ccactgatca actcttcttc tataccatta gctcgcatca atcgccattt
    11701 ataatgatct ccagctcctt tatcatttaa ccatacctga gtcaaattct tgtattgctt
    11761 attttctagc aaatatgctg ggtctaaatg acaatgatag tcgataattg gttggtgttt
    11821 tgcaaattta tgaaaaagtc ttttagctat ttcattctct aataaaaagt tcttatctaa
    11881 aaacatattt aaacactcct ttccttccgt tagtttttag aagagaaaat ttttcctcta
    11941 aataaactcc cttatataat tatttactcg cccccttttc aagcgcttcc caaataccat
    12001 ttaaataaac tgcacctaga gctcggtcat ataatccata accaggtcta ccggtttctc
    12061 cccaaatcat ccgaccatga tctggacgaa tatagccatt aaatccatta tcgtacattg
    12121 tttttaatat cttatacata tctagagaac catattctga tttatgcggc gcttcgtaaa
    12181 aatcgagtcc attgtcactt aaatatttga tattacgaac atgtgcaaaa ggaatccgat
    12241 cccgttgaca aaattcagat agaatttcat agacatcatt atctggtcgt tctgcaatac
    12301 ttccagtaca taatgtaata ccattagaag gagaatccac tacattacac aaccaatcta
    12361 aatcgtcacg atttttaaca atacgaggta atccgaaaat ggaatatggt ggatcatctg
    12421 ggtgaactgc cattttaatc ccaacttctt cacatgtcgg gataattgct ttgagaaaat
    12481 atgcaaagtt ctctcgtaat ttctcttcat caacttcttt ataggcttct aataattgct
    12541 taatttgtga taaccgatga ggttcccaac ccggcaattc aaaattatta gtagaatttt
    12601 ctacttctct aataatttcc tccggatcag tagggatatt ttttgaaata taggctaacg
    12661 tagaagaccc atcatctaaa cgataatcca aatccgattt tacccaatca aatactggca
    12721 taaaattata acagataacc tcaatcccaa attctgccaa attgcgaatc gtctgtttat
    12781 aattctcaat gtattgatct cgtgttggta aaccaatttt gatatcatca tgaacattaa
    12841 cactctcaat aactttcaag gtaagtccat tggcttcgac ttcatctttt aaagatttaa
    12901 ttcgttctct cggccaaacc tctccggctg gtatatccat taatgttcca acaattcctt
    12961 tcattgctgg gatctgacga atttcttgta gtgagatttt ttcttcattt gccccatacc
    13021 atctaaaagt catttccata gttactttcc tccaacttct gttatatatt tattgattgt
    13081 tttacgaact gcttgaggac ctactagcat ttcgcaaaag attttttcag ttttctttcc
    13141 taccccaact tgatataaat ctaaaccaaa gatttcttta ttttctaaaa tttcctgtac
    13201 cgcacaatga atctttgaag gatcttgttc acctaatttc aatactgata atttatcctg
    13261 caactctacc aataacggat caggacttgg cacaaaattt tccccttgat catcgactgc
    13321 cagtaaataa cgtaaccaag cagcaatagc gataggaata aatgttagat tttctgcatt
    13381 tccgtctttt tcgacatact ttttaattgt ttcaccatag cgaatcgcta ctttttgaga
    13441 agtatctgtt gcaattcgtt gtggtgtatc tggaatatag ggattaggca aacgtttatt
    13501 aattacttca tcaataaatt gttttggatc aataatgcct ggattttcaa ctactggtaa
    13561 accttctaaa taacctattc ctttgattaa accaaccaaa tcatcatcct gcatctctgc
    13621 tgaaattgat tgatatccta gcagacaacc tgttactgcc aaagcagtat gaagtggatt
    13681 caagcttgtc gtaaccttca tgatgtctgc tttatcaacc gtctctctat ctgtcataat
    13741 cacaccagcc ttttccaatt taggccggcc atttggaaaa ctatcttcaa taactaaata
    13801 atgaactacc tcagtattag tgaaagcagc aatattggta tgtttttttg tgtgaatgat
    13861 atctaaatcc tcgagcccca tcatcaatag atcttccttt acattctctg aaggatttgg
    13921 cgtaattcga tcaatcatac tccaaggaaa agtcactttt tctttatcct ttaaataagc
    13981 aataaatttt tcagaaacat atccttcttt ttgccaagct tctgcaatcg taaaaatact
    14041 atcttgaaaa cgttgaccat tctgtgagaa attatcagta gaaaccatcg caatcggcaa
    14101 ctctccagca ttaaatctgc tatataacaa ggatgttaca atactcatcg tatgttgagg
    14161 attgctaggt ccagatttga tatcagcttt gactaccgaa aagaattgcc ctttagaatc
    14221 ttttaaactg taaccttttt cagtaatagt aaacgttgta aactgtaatt taggatcttc
    14281 aaaatattta accactcttt gatagtccgc tatattcttc ggattgcaat ataaactatc
    14341 agccgttact gccaaaagtc tttttttgag ttcaccatct ccactcataa caatttccaa
    14401 aatgtcattg ttatagtcat gataagcttt ttccactact tcttcatcaa atgtttcaca
    14461 cacaactact cctgtttcta attcattttg atctgctaag cattgagcaa tttctgcatg
    14521 aaatcctcga taaagatttc ctccaccaaa atgaagccat actggatgtt gctggccttc
    14581 ttgcttaact tctttgacat caaaacacgg cagtagaatc tgcatttcat tgaattcttc
    14641 gatagaattt tgccaatttt taatcgaaac cataattaac ctcctcaaac tgatatgtta
    14701 gttttgatac attttatatt ttaaaaccca ttgtaaccgt tgtcaatata aaaagggaat
    14761 aaacttgctt ttttctacca tatcagaatg attgtatttt ttattcagaa aaataaaata
    14821 ctccttcttt ttggactgat tttatcgaaa cttatttttt ctttttttca tgtattcttt
    14881 tatttttata actagtgtat tacttcaaaa tttgatatta tatggcatga acagaattaa
    14941 aatatcagtt aaaataaaag ttaaggagca ttgtgtatga caattaaaac tagtctccaa
    15001 aatcaagctt accaatctat tcgccgacaa attatctatg ctgacttaga acctggaaaa
    15061 aaagtatcag aaaaaaaatt agaagaaaca ctttctattg gtcgtacacc aatacgtgaa
    15121 gcactgattc aactccgaca acaaggtctt gttgatacaa ttcctcaaag cggaaattat
    15181 atctcattaa ttgatttaga ttcggccaaa aatgctcgat ttgtcagaga acatttggaa
    15241 cgacaaatta tgttagagtg ttgtgccaaa atgaataacc aaaaaaaacg gattttagaa
    15301 actataattt cagaacaaga aaaagctgtt agtcaaaaaa atgctcgtag tttttttcat
    15361 aatgataatt tattccataa agcttgtttt gaaattgcag agcgagaaga agtatggcaa
    15421 tggttagaaa ataacaatac acacttagaa cgatttcgat ggctacgagt aaaaacggaa
    15481 ggattaaagt gggaaaaaat tatggaacaa cattatcaac tatttgaggc attaacaaaa
    15541 caagatccag aagaagctaa ctttctaaca tcgttgcatc ttcatttaat gcttaatgag
    15601 caaaatattg ttttagctac tcatccaaaa tatttcaaaa atatataact tttaactctt
    15661 tttaaattaa atggttgttc tgatcagaaa aatatcgctt gttttcttat tatgtaatat
    15721 atttcataaa ctattctgca taacaactat tgtttgtact ttttacattg gataactaat
    15781 tatgactgct gataactttt gatattaaac tagtatctcc aatacaaata aaaaatagat
    15841 atcttgttca tcaaaattag ttcgtggata cttaccttca tttacatcat tcagcggttt
    15901 cccattttct tttattctat tatttcattt tctaatagac ttggcttcat ttcgcaatac
    15961 tttttttcaa taggcatcaa attggtgttg tttagatatt tagttgtagt tttgtgacat
    16021 gataagtatg ctcctttttc tcttttccac taatacaacg atcaaagggt gcttttttca
    16081 aaaaactaga aaaatcaaaa taagattcgt attttgattc tatatatcct gtttcaacta
    16141 catcttatat ttcacaatag aataaatagc cttttgcata gctgcttaac ttataagaaa
    16201 ttgcaattta cttcttcaaa gtgaaaacga atatgagtaa aataaaatta ttcttcttac
    16261 agataattaa aaatagcgcg taacaaaaat cggcattcaa tcacataatt aggattgatg
    16321 ccgattactt atattctacg tatagtttta gtattcttat tttttatcac cagtaaccaa
    16381 ttgagaacag ccctaaagca gaatagtctt ttatctcaaa acgcttaatt tcaggcttag
    16441 gaatatgaat aatcttttga gtatattctt tctcttttaa tcttactgaa gaaataccac
    16501 tgcctatctt ttttacaaat atttcatttg gtgtacagac taataaaaca atatttgtaa
    16561 tcaatccttg cactaaagaa ttaaaaggaa gactatttaa aacagggtgt gcataactat
    16621 aacatgtgaa gtagttattt tgaactttaa cttttaaaaa ctttaaaaat aatcttattt
    16681 gttcttctaa acaatcatct atactcatat aatcactcca ctaattaatc tccccaaaaa
    16741 gacacagcat taagagatat accaacacaa cagtgcaaat aactctacat cttccttcgc
    16801 aaccttattt caataaacca taaaaattat tttttaatag aaactgaaaa ttaaaactag
    16861 aaaaagtagt tttaccgaat gtaagagcat catcaccatc aatatagaaa tacattcttt
    16921 tccagttaca tttaattttt aaacaaaatt ctccccaaaa aggaactttt tctagtgaaa
    16981 acttggtaat ctctttgtaa ttaattcttg ttaaagaata attaaacact tcatttttac
    17041 ttgttatttt ttcattgact ataactagtt catctggtaa aaaaattaac caacaaacat
    17101 cgacaaacag taaatgatat aatccatttc cacctccaag catattcaat actggtgaac
    17161 atgccttaga aacacgaata tagttatggt ttaaatagat attttcttta aacattgctt
    17221 gtttaaaagc catatgctct tgttctaaac ttttcataaa cttttactct aatgcacagc
    17281 tagcagcagc tgctgcaatt cctgctacaa tatttacctt agctaactct ttagctgcag
    17341 cttttcctaa ttgtttttct gcaattttta ataataaatc cgcagctttt tcaaaattaa
    17401 aagcttttaa tgcttcaata aaatctccct gcgtacctat agcccaagcc actcctcctc
    17461 caggaagaga attaatggct acacatccag catatcgttt ccaatcaact ttctccattc
    17521 taggaacaat aatatgttca taaaagactc ttgctgctct tccttgttcg ttatcttgac
    17581 tgattcgttc acgaatagca ccaaaatcct ttatatggta tacaccatgt tcgtctaaaa
    17641 aaccaactgt atcaaaataa aaagttaatt catctactaa tttattcttt atttctaaat
    17701 caactgtatt cactttttct gtggcataca cacttgttcc agtactaaca aaagtactta
    17761 aacctaataa gaaaacacct aaaacaccaa atattttaat tattcttttc ataatttctc
    17821 ctccataaaa aataagttac tttttaaata tcttgtttat gaattcattc cccaaaggcc
    17881 ttttaagatt gatacagcag tccgttcact tcttttagac ttgtcataca agtcttttaa
    17941 atgatcccat atcagactag tttgtctatc tagcttcaat ccattaaacg ctaatgaacg
    18001 gttcattttt tctattactt tagataaagc tacagaaatt tttatacctt cacaacgcgc
    18061 atcttggatt tcaataatag tatcatcaat tagtttttga atttcttgcc tatcaacata
    18121 ttcaatctta gaaagagaat cttttaaagc tactaatgat tcaacgattt cttttttctc
    18181 ttcagacatt ttcttcctcc ttctagtgac ccgtaaagcc atgtagagca gagtccattg
    18241 aaccagtaat tacactatct acaacgccat tccaatttac tctacatttt ccatttttca
    18301 gatttgtcgg tccatacgga tagccttttt gacattcaat gttcggatta taccagatag
    18361 gattatacca ttcagccgca gaagcagatt cagtcgatac aaacaatccc acaccaacaa
    18421 atccaataca catcacacta tagccaatta gttttttcat ctcgtatcca tctcctaaaa
    18481 aatagaatag ttcttatagt tattcataag acatattttt tccgtttttg ttttatcctt
    18541 tctgtcctat aacaactttt ttcaagtaaa gaatgacata gtttttctta aaaaaacagt
    18601 ctgttttttt ctatttcttc ggtgtataat aaatatgagt gttcattttt tattttaata
    18661 cgcactccgt acataataaa tcttgatcgc atcaatcttt tgagcttctt gacctacttt
    18721 caattgaagt aatacaaatt gagtaacctt attcattgtt tcttctccaa ataacaaata
    18781 ttgatccgga ttctctatat cttgtgtcac ctggtaaagt ttcccagttg ttttcatttg
    18841 tacatgcggg tctacatcaa tactattgtc tttaatacaa cgatctgtca tatagtccct
    18901 cacagcttga ttgcgtttat aaacatctgt gaaattactc cattttctag caaaatcttt
    18961 taagaaattt tttgtcattt catctatttg catttgttgc gctgtctcgt cttctaatga
    19021 accaatttga ctgttacttt cagtactttg aagagttcca cttgtttctt ttactgcttc
    19081 gattgtttct tctgtcgttc tcaattgtgt tttttgtttt tcagaagaaa accaatgaca
    19141 accagtaaga cctatcaaac ataaccaact aaatactaaa attatccctt ttttcacgtt
    19201 tctagtcact gcctttctta tttcacctta cgaaccagac tacgaatttt tgtttgattg
    19261 tacgtgcgtt gataccgagc cataatccgt ccttgctcgg cattctgttc cacactagag
    19321 aaatgttgtc cgccatatga aacatctgtt ataattccgg tgtgaccata gattccagga
    19381 gacaatgcac cacctgcttg ccaattcacc acatctcctg cttgtaaatc acttggtttt
    19441 gggttcatga ttacttgcca accataggtt gtccagttat aatcttcccc tattaacatc
    19501 gcaaacatgt gtccagaacc cattaactgt gggccaccta attgagatac ataccatgcc
    19561 gtaccaccat aacattcccc attatttacg gatcgtccaa tgatccgatc caaaaccttc
    19621 gcattgcctt tactttttcc tgcaataagc gaagtttttt ttgttggtag gctattccaa
    19681 tgcttgatcg caaaagtatc atattccgtt aagttatagg acgttatgat actcattgct
    19741 cctcgataat acggactccc ttcggtaata cctgctgccg catagcctcc acgacctaga
    19801 atcaataaac aacttccagg atctttattg cccacacatt gattaaagtt gctttggctc
    19861 gccaccataa agccataata gtcataacaa gcttttaagt tcggaaactt catatagaaa
    19921 ccaccttcag aaccaccaat tccacgtgca gaaccttgtg ggtagggaca accaggaaac
    19981 caggtaatcc caaaaaagtt cgtatcgttt cttccagatt gtgactgtcc ataagctgat
    20041 tcatagccta attgagaaag aatcacactc ggtaataact gatactttac agctgcacca
    20101 actgctgctt gcgcatgttc atctgtgatt ggaccacgtc ctttaatctc tgaaaaaatc
    20161 ggtaatcctt cggtatattc cccattaaaa gcgacagcta gacctgtagc ttctcctcca
    20221 tgctcagaaa gttctcctga aaaaaagaat ggcaatagaa aaaagggaag aataaagaaa
    20281 agaagacaac ctagacaccc tttcttcatt tcttcctcat cctttcttcg ataatggttt
    20341 ttggactgtt cgtccttttg gtaaagtaaa atcagttcct ggttttgcgt ccaaaatcgg
    20401 cagtgtttta ggatcctttt ctattttttc cgattgctct gttggcttat ctaaagaaga
    20461 aaatgcaggt tgtaacgatt ttggtgcgga aatcgacggt ttactttcag acgaacgttg
    20521 ccccggttgt tgcacagaac gatttcctga tagagtggct accgacgaat taggaacaga
    20581 gtattggttc aataactgct gcattgctgg ataactccca tttttcgcct gatttttcac
    20641 ttggcgaatc tgttgtgaaa gagaaccagc agctgttaat tgtggcacgg gtacttttcc
    20701 agaaggcaac ggaatcgatt gaccaacaaa agcgatacct ttatttaaca atggttttct
    20761 ttgattattc ccttgttgct tactcaattg tgccaatgat tgtacctgtt gttttggtct
    20821 tactgaattc atggacgaat ttggaatcaa accatttgaa agaccagaat tccactctgt
    20881 tttcgatttg gtagaagaca tttcaggctc taccccatga taacgaacat gacgaccact
    20941 ataaggcaag gcttgatttg aacgcccacc tagttcaaag ggattaacca cttgcctccc
    21001 ttttaccgat tcttgtggtg tacgtttttg ttgaaacttt tgaaatccat gtatcgctgc
    21061 agaagcgagt ggattcgttg ctcgatacac attccctgct aatcctgcac ctttgattgc
    21121 caaattttgt ccagcagttg atagttgacc aggcagttgt ttcatttgag acaaagaatg
    21181 acttgctatg tttttcgtgt tgtttatagt ttgatctgca gctcctaacc ctagtttctt
    21241 taataaatct ttccgtttta caatgagtaa aattgatagg agtgctttga caaacatatt
    21301 tcctaaaaaa ccaaaaacag tattcattgg aattaaatcg tctactatgt tatagatcaa
    21361 aaatgccacc aaaataatca cactgtaaaa agatttttga aacatcaagc ccaaaaagga
    21421 ctttaaggta ttcatgagca tataatcaaa tactggaaca aaagaagcga gtaatgaaaa
    21481 aggaatcaca agtaataaac acaacaccaa catttgaaag ataaaacgaa tcatgccaat
    21541 cactacaagt ggtaatccaa tacttagatt aagcaatggc accatagaac caacgactgc
    21601 tttataaaca gctttagttg gttgaatata gacacgataa gccttctttt tccctctatc
    21661 ttctcctgca gcagtggtca cttttgtctc aatatcagat aattcttcac ttgacgcttc
    21721 cttggctaga aattcttgtg gttcaatctc tgcttgatac aattcttcta aatttgttgt
    21781 cccataattt aacaatatat acggatcaac aacagccgct ttataataaa gttggcgcac
    21841 tttttgaatg gcttcctttt gtgtcgttgg cactaaaaca ccattgacat cttttgtcgc
    21901 caattcatct agactatttg tagcagaaaa aataaagcct tctacctcca cggacaaatc
    21961 atttaaccct ttggtaaaag cttctccttt actaggtacg ttactaccat agccaaacca
    22021 aaccattgaa aaaatgacaa cgaagagaaa tcgaataaac accatttttg cgtaatgttt
    22081 ccctctaaat atacgaagag taaatagata taacacatac aagacgacaa tccccgcacc
    22141 aataggatcg tatatttttg aataaatagt atccgaaaaa gtgaaaaact ggtgaattaa
    22201 ctcgttcatt gcagctcctt catagagctt ctcaatgaca aaatcaaggc cttgccaaat
    22261 caatttactt aaactaaaga acatattcgt catcattttt agaaaatctg tgccatttgc
    22321 cccaaataac attttgccta atgaaaattc actatcagat aaataagaag aaaaggtatc
    22381 aatatgaaat ttcccaatct catagatcga ttgatccacc tgcttttctg ccgcatacac
    22441 caatccacca acaaaaagca gtccgaatcc aatcgttaaa aaaaacaaaa cgcaccattt
    22501 cttttcctta tgctttatat aagccattgt ttcacctcat ttctattgca tgattaacgt
    22561 atcctgttct tctacttgag agtgacttgt tttttccgtt gtttgtaatg cagcggtcat
    22621 ttcttcaaac aaactgtgta cattgagttt tcctacacgt ccatagggat ctaacatcca
    22681 acactgtcct ttaatcatgt ggctcatttc agctaagttc gcttcattta cttccaaacg
    22741 taaatgattc aaaatctttt ctcgctcact gtcttcatca aaagcaaaga cgacaccaaa
    22801 attccctttt tctttatctg aacctaagtc accaataaat tgtgtatcta acactaattg
    22861 attcatctgg gaacgcccca cacgtgccat tgctgcaata atactacgtc ctgcgttcga
    22921 attattaaat acccatgctt ctgtaaaata aatcgctgtt ttcttactac tatctcgttt
    22981 tccaaacatt tcacaaaaac gacctaaact aatcatcaaa cacaaagact ttcgatccgc
    23041 atctgtatat agttctggtc ggacattgtc atttggtaat ttcaaatctt ggatctctaa
    23101 aatcgttgtt ttggcattaa agtctaatcc cgggttttct ccataagaaa atcctaaacg
    23161 taaaatcgaa tcttctaccg tcaagcgtaa aaactcacca tattctcgaa cctctttttg
    23221 ttccatttgt tctaaatagt cgaccacatg catcaagcca acttgttgtc cggcttcttt
    23281 ttgaactaaa acttcttgga ttccctttaa taccgcccct tttaaaaggt gattggtacc
    23341 taacggactt aactcatcaa tcatatcctg ggctacttgt ttcgcatcta ctcgggataa
    23401 acaaacaatt ggatctaata caccataatt acggggattt gtagcatcta acgtgacata
    23461 actcattttt tgcaaatgtt ctacaaacaa agggtaatgt ttctgataat acgggtcttg
    23521 aatgagtttc gtaaaccatt tgcgcttttc tcctttggga tccacaaata aactttgtac
    23581 attcataaac gaactataca aaaagagcaa gccaactaaa aaggtcttcc ctttaccggt
    23641 ttttccagtt actgctacat gaggcgcatc aaacaacgca cctttgattc cttccgcaat
    23701 ggctagaaga ttcaaaaaga caaaacgatt tgacgcataa attaattctt ctaatggtgt
    23761 tttttctcct cgagaaccac catcccctaa tgtatcttgc cgaccaatat accagccgga
    23821 ttccatacct aattctgata ctgctgaaaa caaccattcg ccaactgctt ctacagttgt
    23881 tcggtgcttc caatgtaact gccgtcccaa tggttgccct aataaacatt tatagaacaa
    23941 ttctcgttga tcattttttg cacggtggat atggataatc gtatgaagtt gttgaataac
    24001 cgttgcacta ttttgacgaa cttcttcaac cgtttgaccg tatacaataa aacatgcgat
    24061 ccaatcgacg acaggttgcc cattatctac tcgttgcttt aaatgtttta ctaatcctcg
    24121 aacagttaat aagcgttcac taggttcttc atcattttga accaattcct tatgctctgt
    24181 tttgaaccgt tccgatagcc aattcagttt taaaccaata cctccctgtc ctttcaagcg
    24241 tggatagtga attttcattc gcaattctgc tgggaaagaa agatcctgag caaattgaaa
    24301 tagatcacaa tttctcatat tttcaggtgt ttccccaata ggcaacaatg ctaaataact
    24361 actccctaac tcatcttcta attgaagaag gcctttatgt tccttcggta tacgtacata
    24421 cgttccttga ttgtctttca gtacttccca attattttgt tcttctactt tgtgagccat
    24481 tcctcgaata tattgcagac gattgagata caacagctct ttttttacta agggacgaat
    24541 agaaaagcta taaagtaatt gtgtcacttc ttttacataa ggatcacttt cagaaaacaa
    24601 agtttccaaa tcatctactt ctaatccaaa taagcgtgct aaacttcctg ctaaatctaa
    24661 ccagattaga tttattacat catgaaaact ctccaccgtt gctttttctt tgactttgat
    24721 tcctaaaata aatgaaggac gatagacttg accttctcgt tccaacaatg tcactgtttc
    24781 ttttgcataa tacgcaccaa ttgcttgact atcgggagaa aatccctttc ctaatgtgtc
    24841 aaacttcgtc cgtaaattca ttgttcgtgg atacatcacc aactccacat cttcataatc
    24901 tgctaaaagc aacagtaaac gagccatcat ttcttttatt tcctgtgtct tttttggtgt
    24961 gttttttgaa attgttcgtg gaaaaacatg atagtaggcc cagatacaat cctctccatt
    25021 taacaaacaa tttttcttga atgcttttac tggttctttt acaagcacca atgaatttca
    25081 cctcccaata aaaaaggaac aaccagttga ttgtcccttt ttctaatcct ctaaataaac
    25141 atacttattc acaaaaagta attcttccaa tgcattgttt gataccttgt cccagttata
    25201 atacacacaa tcaccattca tcatacgaat catataacaa aaccaatccc ataaataaaa
    25261 atgcactttt tttccatcag gttttagttt tgccagtgct aacacacata aataggggag
    25321 tcctatataa aaaacaactc ctgctggtgg aaaaaaagaa atgacccaac caataaatga
    25381 acgtaaaaat aaatattcaa agattacgac caacaaaaaa gttgctgcat tgactaatgc
    25441 aactggaaat ggaagacgcc aattgcttgt aatctgttgt acgcgataag gttccgcata
    25501 aacaatcgaa taatcataag gttcccaatc cacttcacta tcctcctaat ccataaataa
    25561 tttttcaatg attttaccaa acgcatcaaa tacacgtgtt ggatcattta agaagaaata
    25621 aactgcggca cctgctgcga tagatattaa tgcatttcct acttttgatt tcataaaatt
    25681 tcgcaatccc agataaacaa ccaccattat taaaaaatag ccaccttgcg ttaatataaa
    25741 atctacaatt cccttcagtg tcatttccgt tcttctcctt tcctatccaa ccaattatgt
    25801 gttaattttt caacataata ctgatttgtt tttttcgtaa tgacaatcgt catttgttct
    25861 ttttgtaaaa gtgacgtatc accatctcga aagacgaccg ttgcttttac aataaaaggt
    25921 tttttcgttt ctttataacg caatactttc atctctactt gatcaacttt agctgtttga
    25981 ttgagtcctt caggttcttt catcatgtat gacatatctt ttgcattgtt tttcgcatac
    26041 ttatctaaga aatcttccac aaatccttca acatctttcg cttccgacgc atcaaccgtt
    26101 tcgtataatg tgtcatcata agtaatcatt cgttgttttt ctgtattctt tggtagtgcc
    26161 gtaaaataag gataagcaat aatacgacag cccttgtttg aaatagaaaa gggaagattg
    26221 agtacttgtg tgattgtcac acttgtttct ttcttactct ctggattcat cgagcgaata
    26281 tcataagtta ctttataact agcagttgga atggtttcaa tttcttttaa tccaataaac
    26341 gaagcagcag ttaattttcg aacacctgaa acacttcctg gttcttgaat aaagttttgt
    26401 gcataaaact ctttttttaa tgtttcttga cgttgttgtt cttgttcatg attatcgaat
    26461 gtattcatat acaaagcaac aaaacgattc ataaaggatt caatttcagg tgtgtacgtt
    26521 aattctgacc gactttgtac ttctttcttt tgtaattgtt ggatttcatc tttcaaaaac
    26581 gacacttgaa ccttcgtttt catggattga aaaaatgcca agccccctga aaaacaaaga
    26641 aataaaacca aacaccaaat ccatttcact gctttttttg aatggatttt cttttgcttc
    26701 ggtactttct ctgtataaac tttttctttc cgccgtagtt gtcgtttttt cataagctac
    26761 tccttctagt atgtttttac tagtacgtac gattgacaac gataagcttg tttttctgaa
    26821 aaatagtcca ttcaattacc ctcattttct attccttttc tctttctttt atatccaaca
    26881 aatccagcaa tacttgtcaa cactcctcct agaacagaaa gtgcaacatg tatttcttca
    26941 ccagtctttg gtaagacttt tgtttttcca tctgctgttt tgatttcaat attgccactt
    27001 ggaagtttct ttacaggaat cgacaaatcc tttaccaaat tcccttcact atcttggatt
    27061 aatggaatac catcttttac accaacaatt gtttgatcac ctgctacttt taatggggtg
    27121 gttggtgttg gaatatgggt caattcctct acattactag tgacaatcgg tacactcatt
    27181 ccttgagaag tattcgtcgt aatttcaccg cttggggtta ccgatactgt gacttctttt
    27241 gctggaacaa taggtttatt ttcttttgga attgcttctg atttttcaac aggttgtttc
    27301 ggttcttctt tttgttcttc actggtagac gacatcgttg gctgttccgt acttgacgaa
    27361 tcagtattct tttcagaaga actggttgtt cctgattgtt ccggagttgt gactatactt
    27421 gaatccgttg ttgttgaact atgcacacct tcttcttcga tcgaatcagt cggtaaagtt
    27481 gattcaggaa actctggttc tggtgtcact ggctcttttt caggtttctc tgactgcaat
    27541 tgttcaggtt ctgctggttt ttccgttgtt cctccattta gctctgtctc aacatctggt
    27601 aatccttccc ctggcaatgt ttctacaatt tctgacttag gtgtttctac agtttcatct
    27661 gcataaacca atgaactccc taattgaaac gaaaataatg aaattcctag tgttgttacg
    27721 actgctaatg ttgttttttt catgattatt cctccaattt tttatgcaat tcgtgttttg
    27781 ttcatagacg ccgcactaat attatctgaa cgataaaaga actcccgtcc gttttcttct
    27841 aacccaacat atggattatt tttgaataat tgaatcaata gttcactggt gttgtatttt
    27901 ggatagtttg caaaaaaata atactgtgct tgtcgcccat ccgaaaattc aacaagtaat
    27961 tcataacgat accgcttcaa tccttttcgt tgttttaaag gatctctata ccaacttgtc
    28021 catcgttcca ttcgtggata gagatagaca cgatacacat agaacaatgc cataccacat
    28081 accaccaaaa ataataatcg ccacataaaa attccccctt ttcttctacc tttcttgaat
    28141 catcgaacat tcataccctc tatagagatt tgaaaaatcc atcatcaatt gttcatataa
    28201 acgttgttgc aaatagcgat tgtttcgaat acataattct tcatagccat caatcacttg
    28261 atcttctttt tcatagcatc ttgtagctct atgacgctca gcttgcaaga cataaccaaa
    28321 ctctgcacca tatcgttcta ctgttaataa ctgttgacta cgcaataatg caatataaca
    28381 atcacaaaaa tgttcaaccg acatttgatt tttctcacgt ttgtgaaata ggtattcttt
    28441 agaaagcaca ttattcgtta aacaatctga taaatagcga taatctggcg gtcggttatt
    28501 ttcatctgtg aatttttccc ataataaact gatttttatt cgttcagcgg ctagatagtc
    28561 ttgttcgcgt ggataaaatt catcaatcgc acaaagtttt ttatcacctg aataaacaaa
    28621 tccatataat gcgaaacgaa ctcttccttt tcaattggct ctcctaaaaa ttccagtgac
    28681 ataccatctt ctccttccta aaaaaaataa aaaagcagaa accgatttgg cttctacttt
    28741 tctttccttt tatagctctt ttttacggaa gaatccgcaa atgacatttt ttcaaaaaat
    28801 caatcggcac aagttcacga aaacttggag caattttgga tagaatcact tccccatctt
    28861 gtaaaataca atcataaaaa tcatcagtta cttgatactt acgcttctta caataattga
    28921 taaaatagta gcgatcattt tctatttcca ttcgttgttc tactaagcgc atacgaacat
    28981 catcatagaa ataagccaca aatcgccctt caagttcatg tttttcaatg ggatactctt
    29041 ctggtaacaa tctatttttt cgtcgtttat acattgctgg ataccttaga agaagttcat
    29101 ctaaacgtct gtcagtatat ggtaactgac gaatcaacga ttctaatcgt tctttataca
    29161 gatagaataa ttggcgcaag caatagtgta ccgcctctgg attttctaat actgttggat
    29221 cacgtgacca atacgcacca acataaatca taattttttt catttagaca atcacaccag
    29281 caatactaat gaccgatcca caataggtag aacaagtggc atagcgacca atttcctcta
    29341 attctatctc aatctcttct aaagaaagat atgtctgttc ttctgttggc tggcgactca
    29401 tttcccaagt gacagtcacc aatgaaattt cttccataag aggtttttcg ctgctaagtg
    29461 ctgccacaca gttttcatat atcttcattt tatcgcagcc ttttttaacc gctaaaatcg
    29521 caggtattgg caatgaaaat cgataaaagc gaatgaattc tagccttcct ttccttcggc
    29581 taaattccaa ctcttcgagt tcttgttcgt atcccttacg aacttctaat aagcgtgcaa
    29641 tttcttgcca gttctctttt tcctgataac gtccagcttt taccgcttgt tcaatataag
    29701 gaactcgaaa acgaaaataa gacaaatcaa ccatcttttc atttaatgct tcgattgcag
    29761 cctttaaatc caacaggcgc agccattctg ttgtcgtata tgcattcatg caattttccc
    29821 tcctgacgtt cccatccatt ctagatagtt ttgttgctcg tcatttagtt cggcattatc
    29881 aatcccttct tgtacaaagt ctcttcctaa aatacgatct gcttcttgta acaactttaa
    29941 tgtcggagct acttgtttca aaaaccagcg ttctgaacga tctaatgaga atttttctgg
    30001 ctttactgta aaatccaatt cttccatcga acgaaataat tttgcccatc gtttatcaac
    30061 aatccgtgca tcactttcca gtctatccca aacaataagt tttgcattaa ttaaaccaac
    30121 gccaatctct cctaaacgtt tcggtgaatc acctaaaata aatgcttcta ctgcttgtgt
    30181 tgctttctca ttggctaacc gtaactcata tcgattataa ataccatatt tcgttaatgc
    30241 ttctaattct gaaatttttt ctcggttcgc aatttcaaaa cgtttctcat aaaaattaaa
    30301 aaagagagga ctctttcgcg atccaaaata caaagataat ccttcacttc gaaaatagcc
    30361 atcatctaaa aaacaaccgc caatattctg gaatctctta aagtccattt ctaataaacc
    30421 tgctttttgt ttttctagta attcaaagag atcgaaatgt tcttccgttt ccaatcccca
    30481 aagttcatct aacgcaatat cgaatcggct acattgcaca cgtgtataac cagcttccaa
    30541 ctttccttga tttttccaaa tggaatatag ccatgttcgc caatctgttt gttgttcacg
    30601 catgacttcc tcatattccc ggcaaccttg tcctgaaaat tgcacaagta cattttctgt
    30661 tacagttcgt tttgaatgcc agaacaccca gatattccca cgaacagaaa gacagtcaaa
    30721 aagatacaag cccgttggac gtgtttcaaa ttctgtcaga tccattcgta atacacgttg
    30781 aatcactgtt ttgtagtctg tcccaaaaaa ggaaagacgc aaataatcaa tcattgctcg
    30841 aagatctatt ccgcttttca tatacaatcg aaagcgttcc ttgattcgtt gttcaaaatc
    30901 ctctgggatt tttcttttcc cttgttccat ctttctaatg taatcttttg agcagcccat
    30961 caattgcgca aatcttgctt gtgatagcgg ctttttatct ccacttatat tatgaattgc
    31021 acttaacttc tttctgtagc tttttagctc aatcggtgtc attttctcgc tccttttata
    31081 aaataacaaa atcgattttt ttaacccttt agaaacaccg atatatcaac tagtccccct
    31141 cgttttttgg gaaaagtagt acaactgctg accttagata atcacttgat acaaaagggt
    31201 ttataaaact tttttctatg tgttatgtta tttctgcccc ccatattata tatcgggggg
    31261 ctttacacaa agaggccgtg cgcaagcgca cgacctcttt gtgagctgca cacgctgcta
    31321 gcgagtgcgc attataggcc catgcttcgc agccttaatg cgcaccgcca ggcagagtgc
    31381 ggctaccaga ctacgtctag agccctcccg atagataata actacaaaat taaatgatct
    31441 aattttgtta tttcactata tttttcagga gaaaaaacgc gataaattga caaagttaaa
    31501 tcctcttcta aatctactcg ataatgatac aatcgagtca atcgttctat atcttttttc
    31561 gttagcaata cttgattaat aacttttcct gtaaaaacac gttctttgcg caaaaagcgg
    31621 taatcagtta cttgttcaat acgattcaac caatcataaa acgttctgga agaaagagaa
    31681 ggattaatca ttcgtattgc tgtagctact ctataataac aactctctgc catttaactt
    31741 cacctcctta gttgattaca aaatatgcgc atcagaaaaa cttgttcctt ttggatcttt
    31801 tgctaaatac atttggcgct ctagttgttc ttgtaacaac tgattatcat ctcccatcgt
    31861 ttgatcttga ctatcctctt ttactgtaaa atcatagaca atcatttcag taaatttctc
    31921 aaattctttg ataaagtgat aatctttgta aacaaatggc gcaaaaaact ctacaggtac
    31981 atcaaatcct ggaaaagcat atccacgacc aggttgatct ttgttgtaaa atggcttatt
    32041 tttaaaatct tctccaaaag tcattaaata accaatggga gacaatcgac caacagaaat
    32101 acggaatgtt aaattatccc gaacaccact tggaaaatat tctgcatctg gtcgttgcat
    32161 tgctaaaata atgtacatcc ctgcttgacg accctttaat actaatggct gaatcaattt
    32221 atcgactcta tttctcgctt ccatatccaa cgaaccataa aaagctgccc attcatcaaa
    32281 aaagataaaa tgcggtggta acccataata agcataattt ttccctggtt catatttagg
    32341 atctttcatg gttttcatat aggcataccg ttgattcatt tcttttaatg catttcgtaa
    32401 acaaataatc atttcttcat ttattttgta aaacacatgt cctttgaata catcgacgtc
    32461 acctaatgct gctaaatctg ccgcttttcc atcgcaaata tctactgtcc caacacttaa
    32521 acaagcttga attaaagaat acaataaata ggttttccca ccaccgattg caccagcaat
    32581 caacatattt ggtgattgat catataccca atccaaagtt ttcattaaat gaatacgtcc
    32641 attttctgct atacattgat caataggaat ccgaccagaa tctgaaagga atacataatt
    32701 gattcgggct ttttctcgtt cttcacgaat taaatcacgc aaaaatactt cagataacaa
    32761 atgacccatt tttaaaaatc gttcgtgaaa acgcccacca tctaaaggaa aagaaaccac
    32821 taattcttgt ttcttttgat aaaaataaac ttttggtaat ctcatttttt cccttgtttg
    32881 tttctcacta acttgtttct ttgtataaac aaaccgattg tcaattaaca ttcgaacaag
    32941 taactgacgc caataaacag aggcaaaata tccttctttt agtcgcgacc aatgcatcaa
    33001 ccctaaaatt aacccactaa ccagcaacaa atacaacaca atacttattc caggaataag
    33061 atacatttgc caattcgaaa acgtacttaa acgtggataa aatactttcc aactaaacca
    33121 acctaacaga atcaaaaatg gaaacaaaaa gaaaccataa tagcaaaacc ataaataacg
    33181 attgaaatag cgaattcgcc gaccacgata cttgaaaaaa tgagctttca attgtcacat
    33241 tcctcctttc tgtttttact tttcctgtgc taaaaacttt tgacaaaaag caactaatac
    33301 aggaatatca catttagtaa aaaaacataa tcgaaaaaga tttaatcgat ttttataagg
    33361 gtgtgcacac atattacata ttcgtactat acgaatccaa atcacttcct gatgatcttg
    33421 tttccactgg tacggtaatg aaaaacgaac aagatcacgt aaaaacatac actgcccaat
    33481 aaccgcacaa atatatgcat ttgtttgtac aaaaatcgtt ggattgtctc caaaatactc
    33541 aatcaattgt tggatatttt gataacaagc acaatctctc aaagtatttg attggtttta
    33601 tctgaattca aaatctcccc ttccttctat cttagataaa aagaatagga agactccttc
    33661 ctattctttc aaaaaaacct tattttttct ctttttcctt agaatcaaca cttggttgtt
    33721 tttgatctaa acctttttct tgtgattgtt tcatattagg attatttgtt ggagcttcta
    33781 ctttctctaa tcctttcgca taaatcacta aatctgaata ttcacgattg ccatcttgtg
    33841 ctggaatata taccacatga tattctggat caattaattt cacaggatca cgtcgtttaa
    33901 aaccagtcaa atctacatct gctggaaatt taactcgtcg tgcaatcttt ggttcatctg
    33961 gatttccaaa aactaattgt gctcgctgtg atcgaatttc tcccgtataa tcgcctgttt
    34021 cattatcaaa tacacgatca gactcttcta atgcgccaaa gcgtacggct cctaaacaag
    34081 tttcatctaa tgcttctgta atgtcataat tatttggaaa ttttaatccc atcttacaaa
    34141 acctccccaa tttttacacc agttaaaaag acaccaacat cttgatagcc agttgttcga
    34201 cgctctgttt gtcccatatc atttgtttca cgactattca ctcgttcttt acgaaaaaca
    34261 aaataagctt cttcaaatga aatacgcacc tctttttctg gtaatcgtaa tcttttatcc
    34321 tcttcagctg tgagataaac aaaaaaagca ggctgttctt ctcgcgaaca ctctgcttgt
    34381 aattgaacat atcgcccaga cacaccatta atttcctttg gtggattagg ttcccgtgaa
    34441 cccaataaaa atacttgacc taaaaactct ttcttcatac gcaatgcttt ttctgccata
    34501 aagtttttcc tcctcttaaa aaccaaaata aattctaaat atttctacat tacaatcaaa
    34561 caagcggtta aaaatcctaa ccgcttgttc ctcatgacta atctttggct ttacgtactt
    34621 tataaagtgt tatacctaaa gcaatgacta atactactaa tccaagaacc ataagtatac
    34681 tacttgtttg ttcacctgtt tttggcaaca ttggtacaac agtagctggt ttaacccgtt
    34741 gttctggttt cactggttgc ggtggttttg gcgcttccac aatttgaacc gtttgatctt
    34801 tgtttgttag atctacattg tgtttcgcca cttcttcaaa cgtttctttc tcatcttccg
    34861 ttttcgcttg gagccattcc gcaaaactca agccttttcc tgcaagattg cgaccgtcca
    34921 ctaagaattc aaataagaat tccatcattt ctttatcggc cgcaaagact ttttccgcat
    34981 gagtgccttc aaatggtgtg ccgtctggtg ttaagtagcc ttgaacaatt aagcgataga
    35041 tttgaccaat cgcaagaccg tctactttga cccattcaag cacagtttga tttggcaagg
    35101 ccaagatctc ttttccgcca tttttattcg tcgctttcgt cgtaatggtt ggattactga
    35161 ttttgatggt ttggtcattg tcggtaatat ctgcgtgaga agccaataat acgccttctc
    35221 taaacagatc ttcaaagacc acgacttctt tgcctcgcaa cgcacgtgcg tctagaataa
    35281 agtctagatt gactgtacca tccgttgttt ctgccacaaa cgttaaggta cttgtgactt
    35341 cttttccatc tactagcact ggtttttccg ttactttgtc cattagaaca ccgttgactg
    35401 tgtatgtttt tccaacgacc aaatcgtggt atttcacagc gtctgtaatg gtgactttcg
    35461 ttaatggatt aacctctttc aagccagtgg gtttatgtgt agccgttgta cgtacacttg
    35521 ggttagttac tcgtaccgtt tgccctttgt cgttgatgtc tttatggttt gctagttctt
    35581 catcatttct aaaaagactt tcaaacacga cgatttcacg accatttata cctgtcaaat
    35641 caaaggtaaa tggtacgatc accgtttcat tttctgcttt ggcaataaag ccaacactcg
    35701 tttctaccgt atttccatgc acaagcaagg gttcaccggt tgctttatcc attaagatcc
    35761 ctttgaccaa gtatgctttt cctggaagaa tctcggtaat ttcaacggta tcgtttaagg
    35821 taaacaatcc tgttgggtct gcgactgtca atccgtcttc aaagacagcc gtggtatgaa
    35881 cggttggatt attcactttc acactttggg cttcatcgtt gatatccgca tgtgctgcaa
    35941 cttcaatgcc atcacggaaa agtttttcaa aaacaacgat cgtttgacct ttcagaacac
    36001 tagcattaac cacaaattca aggtcttttg tgccattgac tttgtctgca ataaaggcca
    36061 aggtacttgt gatttctttg ccatcttgta aaattggcgc attcgttgcc ttgttcatca
    36121 atactcctga aatggtgtat tcttttccga caaacaagtt ggtataagaa acactgtctt
    36181 taatgacgat cgtttctaat ggatcaacca ctttttcacc atcggcttta tttgacgctt
    36241 gtgtttctag ttttggtgga atcaagtaat tacgtacaga aaccactaac gtttccccat
    36301 catctggcgc attttgtttg aatgcaaccg tgaatgcttg tttatctgta tttggttgga
    36361 aactttctaa tggggcattt tccaagaagt aatagtcatc ggcaactaga cctttcacta
    36421 aaatttcccc gttttgatca gtggtatatt caccaattgc ttgattttta ccgttataca
    36481 aggtaaagtt cacacctgcg agcggcgttt tcttcttgtt ccattcttca tacttgaata
    36541 attttacact tttccgtgct tgacggttcg caaaatggat cactttgatc ggttctgtat
    36601 cattggtaat cgagaacact aatgggtttt gattcaaaac gtaatttacg ggggctttga
    36661 tttcttccaa acgatagcga tcttttccat aagtaagtgt accgttagtt aggaaaaagc
    36721 ctttttcatt ggttttaaag atatccgttg tttctgtatc atttggaatc tccattgtga
    36781 cataacgatt ggctaaagta tcaaaaatct tgaattctgt attagcaagt ggaatcactt
    36841 ttcctgtttc ttgatccact ttcaccactt taagacgttg ttcaattact ttatcttcta
    36901 aaacataatg gaaagtttgc ccattttcag aaattgtgac ttcaagtggt tcaaatagtt
    36961 tatacccttc ttttcctttg gtttcagaaa gaatgtacgt atcaaagaca acggtatttt
    37021 taccaaaagt agcataacca tcattgtctg tcacaacggt tttcaccact ttgccagttg
    37081 tttttgacgt caaagtgatt tcaatgccag ctaattttgg tttgttatct ggattcgttg
    37141 aatcgactaa atctttatta gcaactttca ctaaatcaat ggttcctttg atcacttgat
    37201 cttttgcggt cgcattgaca gtttttccag gttcaacaac aatttcaatt gcttcatcag
    37261 aaagcacata accttttggc gctttgattt cttttaaaac atatttgcca ggatcaagat
    37321 ctttaatttc tgcctgtact ttgccgttaa tttttttcaa ggtaatttct ttaatctttt
    37381 tcccatctgc ttgatacaaa ccatagaccg cattttctaa agaagctgca ccttgtgctt
    37441 tcacaccagt ttccgcatct tctttaaaca cacgaatgtt tccttgtttt agaatttgta
    37501 aattaataac agacgcatta ggttctgttg gatgtaacac accaattgtt tgagctcctg
    37561 gacgacgata ggctaatggc gcaccttgaa ctttaatttt attcaattga atttttgctt
    37621 tatccggtgc ctcttttgtg actgtaatcc atacttcatt gccgtgaata gatacattga
    37681 caccttttgg tttttgaatg tctttcacat atttcaaaaa atcattttta ttctttactt
    37741 tcaacgtttc gccaattttt accgtatgtg tttgattatt aaaagttgct ttttcaccaa
    37801 agttattaat caaacgttga atttctgctt ttcgacgatc ataatcaaca cggatatttt
    37861 tgattgggat ttttgtgccc aaagcttccc aaatcataaa ttgtgccgca atgtattgtt
    37921 catcggattt gtctttattt gtgacatatc ctaaataaga gatcaagctt gtttttttcc
    37981 gtacatttga atttttcaaa tagtttttca aagcagtagc tgtataaact tgaccttctg
    38041 cggctgagac accaggctca atacaaaacg ccacttgtcc attaatctca aaacgaacca
    38101 tataatttaa agtgaagttt agattgttcg gactagaagt aacaccaata ttttcgcccc
    38161 aatcaatttt ccgaccacct aaaacagctg cattggttgc acggcgaaca cgaaccgaac
    38221 gattggttgg tactgttact aacagtgtag gtgtacctgt ttttggaatg ttctgctctt
    38281 ttttcttttg attttcaata ctagccgtag attctttgtt tggtttcgtt ggttgatttt
    38341 gactagctgc ggttgaagag attgtttttt caacgttttc ctcatttttt ccttctttgt
    38401 cagcagtagc cgctggttgt tccactgttt cttctattcg tttcttttct tccgcttgtt
    38461 tctcagaaga ctctggctgc acagaaggcg ttgcttcggc agctttttct ccttctagag
    38521 tggacgtttc tgaagcaggg gttgtaattg aggcagtttc ttcaactggt tgtgaagtac
    38581 caggactatt ccctgggtgt tgtgtttccc caatcgtctg atcgagagtc gttttggaat
    38641 tgaccgttgg cgcttctgtc acaggggcct gttcaacagt ggcttcacca gctgggaccc
    38701 cggcttctgc tggttggact tctgtcactt cagaagcgac ttgggcaatg gcttccatcg
    38761 taggttgtat agccgtcgtt tcttctgcat gtgcttgagc agttcccacc aagaaacaga
    38821 attgagaaaa agccaccaat gcgagtgctt tcaaccaatt cattttcgtt tttgcataca
    38881 caagaattcc tccttttcct gagaatttta tataataaaa caaaacgccg ttaccaaaag
    38941 tgataacgac gtgaactgtc tcttctattt ttatctggcg ctcttatctg aacacatttc
    39001 atcaatgatt ttaccctccc actataatta cagaacaaaa aaagaacctg cttcgtggaa
    39061 atcaactgtc catttcccaa ttggaatacc agcttttttg gcaacttcac catcaccaaa
    39121 tctcatgcca taccaattac taccttcatc cttaatttct ttccaaccat atgacatagc
    39181 ttcatctaat gaatcaaaaa tcatgacact attgccaatt gttacaggat ctggcttaag
    39241 atcttctgga agagaaatat caatcatacc ataatgatcc gattcctcag tattattgtc
    39301 attactagct actggtttgg ttgttctact ggcttatttt gatacaacaa gtactcttat
    39361 tcttctttta cttctccgtt ttcaatttcc cattcaaacc actccgcaaa gtcttgctta
    39421 aaaccatcta ctcgatacct attttgtaaa taggcatctt ctgacgtcgt aggatctaaa
    39481 taggtaggtt tattctctgg acgagcatag acacctaccc atgtttcgta atctccttca
    39541 aaataactat ctaccaaata gccttttttt ctaagaatct cccgaacttg atttttaatt
    39601 attgatactt gttcaaaacc atcactcatt ctatcacctc aaataactct agattctcat
    39661 aaatattccc gacaatttca atcctatcaa tgatctctaa caaatcgcta cttatgcttc
    39721 cccattcgta taagaatttc ccttccgcaa aataaatttt ccataaactt cttcatgatc
    39781 gtcccaacca atatcactct cgaaaaattc cacgttgttc ttatctttta gctcagtaaa
    39841 tgccataagt tcaacatgtt ttccaacctc gaaacaatca caccacccat caaccgttac
    39901 acgtgtgcct tcaataccta agaaactttg tcctcgtgta ttaaacacta aaactttccg
    39961 cattttttgc tcattaatta atcacgcgcg aaatctagga atcacaactt attcgcttct
    40021 tctttataaa taaaaaaact ccaataatcg gaaattacta tcttttcctc attccttttt
    40081 taaatcttca tacttcttct tatctttgtc ctaacctaat aacacaaatt ttgaagaaaa
    40141 actcagtaaa acctgattct ttttttatct tcacaacaac caactttttc ttcagatcct
    40201 tttactagaa cttgtataca aaaattgttg aatgctgata taatttgcgg ctacttgaaa
    40261 aaacgataga tgtaaaaaga taaatagaat cattttttat tctatatcag tctatgattc
    40321 attgcttatc aatcacccaa cccattcgat gccgtttttt ttagagaaat ttaaaaaaga
    40381 ccgtacgaat ctcgcattat ccgattactt ttccagaaaa gatccccaat tctgtataaa
    40441 taaccctatc ttcttgttgg tttcattttc tcatataaga attcagtcaa tctacccact
    40501 atgaccatta ctacgtccaa cacaactgac atattaacca cgtaagtatt ccctcacaga
    40561 tctccgaatc tccatggtat ggattcccat cctgacgctg cagaggacaa catatttcat
    40621 gtggctctgt acccttttga tttggaaaca ctacaaatca atactcatct ataacttatc
    40681 aagcgaactt tcgctaggct tctagtgatt actaaattgt tggataacat acatagccca
    40741 ttttatctag ctgttattca taacagttag ttcttgtatt acttcttccg cttgtgttgc
    40801 cattgagctt gtcaaaaagt tacttagaaa aaagctgcca gtaaagcaac tttcaacaaa
    40861 ccctttttgt ttcttatcat atcaagaaac ctccttttat aaattttttc tataataaaa
    40921 aacgtcgata acttaataag tatcgacgta aactattttt atatcccgta aatcaaaaat
    40981 tctaaagaaa gatttcctat ataagcatat tggataattc gattagtatt gggtatatct
    41041 ctaccattct catacctatc tatggaccat tttgaaattg aaggagaaaa aagctttcca
    41101 aactcctccc tttctagata ataatctttc ctaattttcc tcatccttaa tcccatacta
    41161 aaagaattta tctttttaaa atcgctaact ctttcatctt ttggaagtat attcttataa
    41221 tcttctccgt acataaggta aggaacagtg accttaccaa gataggcaat attcattagt
    41281 ttttcaatat ctggaatatt aatacctttt tcccatctac ttataacatt tttgcctgta
    41341 tagatggtaa agtttttacc aaatttttca agcgtctctt cccggttctt tcggacttct
    41401 cgtattcttt ttcccataac aattttatcg tcttttgata aactaaatat ctcactatca
    41461 cgattaatct ccttcaaaat ttctttttca ttacttaata gaaaaatatc gatttttttt
    41521 tgcatttctt ttgacggatt tctctttcta tttaacacat aactgagtaa tacttcacta
    41581 attcctatat tatcagctaa ctctttgtta agtaacttat tcatatctct gtatgcaatt
    41641 agtttaccga tgagaatctc aatcttatct tcctcatctt ttattagagt ttctatattc
    41701 agaatcttgc ttagagtatt atctacgtct ttagggattt ttcttgaccc tttttcatat
    41761 ttaactaaag tactttgtga aatacctgct aaatcagcta actttttttg agatagtttt
    41821 ttctcttttc ttagagattt aagaaccctt ccacttgaat tatcaaccat gaaaaaagca
    41881 cctcctatga gatgctttca tcatatactg acagctaaaa atcttcaaga aaaatattcc
    41941 aattttgtta attttagtat cgccgtgata accaaatgac agtttaaaat cttttataca
    42001 gataatcctc agtgttgcat ctactcaaaa aggtttattt aataggtttt tcgattgatt
    42061 ataagttatt tcacactatc ttgctcatcc attttcagaa cggccatgaa ggcttcttgc
    42121 ggaacttcga cggagccgat ttgtttcatc cgcttcttcc cttctttttg tttctctaag
    42181 agtttacgtt tacgagaaac atctccacca taacatttag ccaagacgtt tttacgcaag
    42241 gctttgatgt ctgaacgggc aacgattttt tgtccaatag ctgcttggat tggcacctca
    42301 aattgttggc gtgggattag ttttttcagt ttttcaacga ttgcttttcc acgttcatag
    42361 gcaaagtctc ggtgaacgat aaagcttaat gcatcgactt tttctccatt cagcaagatg
    42421 tccatcttca ctaacttgct tttttgataa ccagacattt cataatccaa tgaggcatag
    42481 cctttcgtgc ttgatttcaa tttgtcgaaa aagtcaaaga caatttcaga aagcggaata
    42541 ttatagacga catttactcg gtaatcatct aaataatcca tcgtaatgaa ttctccccgt
    42601 tttcgttgag aaagttccat tactgcaccg acaaaatcat ttgggaccat gatctgtgct
    42661 ttgacgaatg gttcttctac atcctgaatc gttacaggtt caggaaaatc tgccgggtta
    42721 tctactgtag cagtcgtacc atccgtttta ttaacatggt aaataacgga tggtgcagtc
    42781 gtgatcaatt ctagattgaa ttcccgttcc aagcgttctt ggacgacatc catatgaaga
    42841 agtccgagga atccacagcg gaacccaaaa cctaatgctt gagaggtttc tggttcgaat
    42901 tgtaaagcag catcattcaa ttgcagtttt tctaaagctt cccgcaaatc gttgtaacga
    42961 gaagtatcaa ttggataaag accacaataa accatcggat tcatttttcg gtaacctggt
    43021 aaagcttcag cggcaggatt gtctgctaac gttactgtat cccctactcg tgtatcttgg
    43081 acagttttga tacttgctgt gatataaccg acatcaccga ccatcaaaaa gtctctagca
    43141 actgcttttg gcgagaagac cccgacctct gtaacatcaa atgttttgcc attactcatc
    43201 agtttgattt tgtctccggg tttgaccata ccgtccgtga tccggacatt tagaacaaca
    43261 ccgcggtaac tatcataaat agagtcaaag atcaaagctt ttagcggtgc atctaagtct
    43321 ccacttggtg caggaacata ttccacgatc tgctcgagaa tatcttcaat cccaatccct
    43381 gatttggcac tggctaatac agcttcacta gcatcgattc cgattacgtc ttcgatttct
    43441 tgacggacac gttcgggatc tgctgcgggt aggtcgattt tattgatgac tggcaggatc
    43501 tccaaatcat tgtctaacgc taaataaaca ttggccaatg tttgtgcttc gattccttgt
    43561 gctgcatcga ccactaaaac ggcaccctca caggcagcaa ggcttcgaga gacttcatag
    43621 gtgaagtcga cgtgccctgg ggtgtcaatc aagtgaaaga tatatgtttc tccatttttc
    43681 gctgtgtaat tgagttctac agcatttaat ttaatcgtga ttccacgttc acgttccaaa
    43741 tccatcgagt ctaacagctg atcttgcatt tcgcgagacg tcacagtgtg cgtcatttct
    43801 aaaatacgat cggccaatgt agatttccca tggtcgatat gagcgatgat cgaaaaatta
    43861 cgaatctgct cttggcgttc tttcattttc tttatatcca tagcgtctcc tcttttcata
    43921 taatcagcac tttccattat accaacgaaa agcagtaatt taaagagttt ttaattagtc
    43981 agctatagaa gttttttttg tagaattttg ctatactgtt atcaagctaa taaatggaga
    44041 tgaaaaaatg gatcaaaaag attttagaga aaatcttgaa ttaaaaccgg tcactcaaga
    44101 acatatcgat caattcaatg aattgctttc ctatgtgttc caagtgactg aagcagacat
    44161 cgaggaaagc gggtttgaga ataaacgagc ttttatccgt tccaaaaaac cgattttgga
    44221 agtatcgaaa gtgttcggat ggttccacga aaataaactg atctctcaaa tcgctatcta
    44281 tccttgtgaa gtcaatattc acggtgcacg ttataaaatg ggtggtgtga ctggagttgg
    44341 aacttatcca gaatatgcta accatggatt gatgcaagat ctaattatcg ttgcattgga
    44401 taatatgcgc aagaataagc aatggatctc ttatttgtat ccttacagta tcccctacta
    44461 tcggcgtaaa ggatgggaaa tcatgtctga taaactttcc tttaaaatca gagatacaca
    44521 gctacctaaa caaatcccag taagtggtat ggttgagcga ttaccagttg atcatccaga
    44581 cgtattttcc gtttatgaca aatttgccca acaaaaccat ggtgctttat tccgcagtga
    44641 ttttcattgg gaagagtatt ggcgtttcga aaatgaagat gagcgcacag ccgctgtcta
    44701 ctacgatagc aaccatgaac caagaggtgt tctgttctac tgggtagctg aagaaatatt
    44761 tcacgtaaaa gaaatgttct atcttgatca agaagctcga aatggcttat ggaactttat
    44821 ttccgcacat ttttccatga tctactgggt acatggagat atttataaaa atgagccttt
    44881 agcatttttg attgaagata gtcagatcaa agagcagatc gaaccatatt ttatggctcg
    44941 gatcgttgat gtaaaagaat tccttcaacg gtttccgttt gttggaacag ctgatgcttt
    45001 tcatttcatc attgaagatc ctgtcgctcc ttggaataat ggtgtcttcg ctttaacatg
    45061 ggatgaacag ggacaagtcc gtgtcttaaa tgaacctata ggaaaatccg ttcgactgga
    45121 tatccaaaca ttgacttgct tgatgatgaa ttatcgccgt gcttcttatt tggcaagaat
    45181 cgaacggtta gaaacagatg aagaaacact gaagtcacta gagcgtatca ttccaaacat
    45241 ggaagcttac tttagcgatt atttttgata aaaaggatga tgtttagatg aaaatttatt
    45301 ttgccgcacc aatgtttgct aaaagtgatt tgttatataa ccaacagtta gttaaagaaa
    45361 tcagagagct ctcttctgag ctttcgatct atcttcctca agaaaatgaa gcaatcaatg
    45421 acaaaactgc ttatgcagac agtcgaatga ttgctcttgc tgacacagaa aaagtgttgg
    45481 ctagtgattt aatgattgct ttactagatg ggctgacgat cgatgccggg gtagcatcgg
    45541 aaatcggtgt ggcttatgcg aaaggcatcc cagtgatcgg cttatatact gatactcgac
    45601 agcaaggcgg aacccacccg aaaaaaatcg ctgcactaca agaaacagct gaaaatcaat
    45661 ttcactacct gaacttatat acaataggtt tgatcaaatt gaacggaaaa gtggtttctt
    45721 cagaaattga gttgctttca gaagtaaaaa gatttttaga tggagggact ttcagtgatt
    45781 aaagaaatca aaaaggtgca aatagcttta cttgcttttg gtgtattcgt tgtctgctat
    45841 aatttttatg aatttatcac acaaaaatat tcgacttctc aaggaatcac atttatcgtg
    45901 gaatctttat tagggattgc attgattttc atgccacaag tcattttgaa agttttcaaa
    45961 cttaaaatac cagcagcaat cgttttgttt tactggtttt tcttgttcat ctctgtcttt
    46021 ttaggcacag ggatgcattt gatcagtatc atctcttttt gggacaaaat cttacatgcg
    46081 gtgagtccaa tggtcctgac agctcttggc tatggattga ttggttactt gatgaaagat
    46141 gctgagatat caaaaaccag tccttggttg ttcctcttat tcggctttgc gtttgctgga
    46201 ctttgcggcg tgttttggga gttctgggaa ttcttatgcg accagttctt aggcatgaat
    46261 cttcaacgtt ttgctgcttc tgatggcaca ctgtttgtcg gacgagcagc attgatggat
    46321 acgatgggcg acttgctgac aaatacgata ggtgctgcct taatgggatt gtttgcatgg
    46381 tctcaaagta aaaaagatga gcgttacttt gaaagttata aattagaaaa agtgaaaaat
    46441 acctaataaa agaggttgtg acagaagcgg gcagcttcaa gaaatttcgg cttatttttc
    46501 gaagaaacta cttctggaac actgtttatt tgaaaaaagg aggtctgaca ctagttgtgt
    46561 cagacccctt ttttctttta tagtctcaat ggaagattag acgatttctt ctagctcttc
    46621 tgttttgaaa tgaagttgtc catcaagtaa agtaatcgtt acttttgatt taggcataac
    46681 atgtcctgca acgatttctt tagctagtgg tgtttctact tccttagtga taaatcgttt
    46741 caatggtctt gcaccatatg ctggttcata agcattttca gcaatccacg ttttggcttc
    46801 atcactgatt gtcagcagga tttcttgatg ttccagacgt tgtgccaatt gcgccaccat
    46861 tttgtcaacg attcctttca cgttgtctag gctcaatggt gtaaataaaa tcgtgtcgtc
    46921 gattcggttc aagaattctg gtttgaagtt tccacgtaat agcgtgttga cttgttcagc
    46981 cactgcttct ggaatcgttc catcagcagt cacgccttcc agcagtaact gtgaaccgat
    47041 attgctggtc atgatcagaa ccgtattttt gaaatctact actcgccctt ttgaatcagt
    47101 caagcgtccg tcatctagga cttgtaacaa gatattgaag acatcgggat gcgctttttc
    47161 gatttcatcc aacaagacga ttgtataagg atttcgtctg acagcttccg ttaattgacc
    47221 accttcttcg taacctacat agcctggagg agctccgact agacgagaca cagcatgttt
    47281 ttccatatat tcactcatat cgatccgtac catatgatct tctgagtcaa acaagttctc
    47341 agctaacgct ttcgctaatt cggtttttcc gacaccagtt ggtcctagga aaaggaaaga
    47401 acctagagga cgatttgggt cttgcaatcc agcccgtgaa cgaattaccg cgtcactgac
    47461 cgcatcaact gcttcatctt gaccaatcac tcgtttatga agtgtttcat tcaatttaat
    47521 tagtttttct cgttcacctt ctacaagttt cgttacgggg atacccgtta atctgccaac
    47581 gacttgagca atctcatttt cggtaacgga ctcttgaacc atcttaatct cgctgtcttt
    47641 tgctttagct tctaattcct tcaattcttt ttctaattga ggtatcgtac catgacgcaa
    47701 tacagcagcg cgttctaaat catagttatt ttctgcatct tctaattcgt gttttgcttt
    47761 atcgatttca gcacgttttg ctgaaacaga attgacttct tctttttctg tttcccactg
    47821 catcttcatc gcatttgctt cttcacgaag ttcagctaat tcttcttgca aatttttcaa
    47881 gcgtttttta cttgcatcat ctgattcttt tttcagtgca gcttcttcga tttccaactg
    47941 catcaaacgt ctagtaactt gatctaattc cgttggcata gagttcattt ctacccgaat
    48001 cgttgcactg gcttcatcga tcaaatcgat tgctttgtcc ggtaagaacc gatcagtaat
    48061 ataacggtca gataaagtag ctgctgctac taatgcgttg tcatggatgt taacaccatg
    48121 gtggatctca aaacgttctt ttaatccacg cagaatactg atcgtatctt ccactgttgg
    48181 ttctttgact aatacctttt gaaagcgacg ttccaacgct ttgtcttttt ccatatattg
    48241 acggtactca tctaaagttg tggcaccgat caaatgtaat tcaccgcgag caagcattgg
    48301 tttcaacaga tttccggcat ccatacttcc ttctgttttt cctgccccta cgatattgtg
    48361 gatttcatcg atgaacaaga ggatacgtcc atcacttttt ttgacttctt tcaagactgc
    48421 ttttagtctt tcttcaaatt caccacggaa ttttgctcca gcgatcaatg cacccatatc
    48481 taatgaaaaa atcgttttat cttttaaatt ttcaggcaca tctttgcgta cgatacgttg
    48541 agcaagccct tcaacgattg ccgttttccc tacaccgggt tctcctatca gaacaggatt
    48601 attttttgtt tttcgtgaaa gaatacggat gacatcacgg atttcttcat cacgaccgat
    48661 gattggatcc atttttccgc ttttgacttg ctgtactaaa tcaacgccgt atttttctaa
    48721 tgctttgtat tgttcttctt ggttttgtga ggtcactctt tctcctcctc tcatctcttc
    48781 gatgttttta cgcaattctt tttcagataa tccgttttta ttcaaataaa cagttaacgg
    48841 ataatttttt aatttcatca acgctaaaat aacgacttcc gttgaaagaa actcgtcgcc
    48901 gaagctttca cgtatttggt ctgcttcatt caataatcga aagaaattct ggctgaggtt
    48961 ttgtccatat tggacgtttc caccagaaac aactggatac tcatccagta gacgatcaat
    49021 ttcatgttca aaagattcga catccaatcc ggcatccgta tagaaatttc gaccaaaatg
    49081 attagattgt aaaaagattt tccatacatg ggcaatgtcg atatcttgat gttttcgagt
    49141 gaccgcaatc tgttgagctt cagcaatcgc ttcttgaagc gtcgtagtca ttttctcaat
    49201 attcatacag gtataccctc ctaattaaag gtaagatcac ttatttcttt gatctttaca
    49261 aaaactatta tatcgctttg gtcaattttg gtcaaaatat acacatagtt ttttgacttt
    49321 ttttctcgac ttatataaat cttaaaaaaa caaaattgat tgtatgtata ta
//
LOCUS       DAFLVO010000012        48297 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.012, whole genome shotgun sequence.
ACCESSION   DAFLVO010000012 DAFLVO010000000
VERSION     DAFLVO010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48297
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.012"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(52..1581)
                     /gene="ahpF"
                     /locus_tag="L1U99_000736"
     CDS             complement(52..1581)
                     /gene="ahpF"
                     /locus_tag="L1U99_000736"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HBN1211301.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(1591..2154)
                     /gene="ahpC"
                     /locus_tag="L1U99_000737"
     CDS             complement(1591..2154)
                     /gene="ahpC"
                     /locus_tag="L1U99_000737"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBN1211302.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(2298..2960)
                     /locus_tag="L1U99_000738"
     CDS             complement(2298..2960)
                     /locus_tag="L1U99_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1211303.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            3144..4790
                     /locus_tag="L1U99_000739"
     CDS             3144..4790
                     /locus_tag="L1U99_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBN1211304.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            4781..5863
                     /gene="uxuA"
                     /locus_tag="L1U99_000740"
     CDS             4781..5863
                     /gene="uxuA"
                     /locus_tag="L1U99_000740"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBN1211305.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(5971..7524)
                     /locus_tag="L1U99_000741"
                     /pseudo
     CDS             complement(5971..7524)
                     /locus_tag="L1U99_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            7672..8813
                     /locus_tag="L1U99_000742"
                     /pseudo
     CDS             7672..8813
                     /locus_tag="L1U99_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(8939..10018)
                     /locus_tag="L1U99_000743"
     CDS             complement(8939..10018)
                     /locus_tag="L1U99_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBN1211306.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(10121..10561)
                     /locus_tag="L1U99_000744"
     CDS             complement(10121..10561)
                     /locus_tag="L1U99_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1211307.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(10618..11028)
                     /locus_tag="L1U99_000745"
     CDS             complement(10618..11028)
                     /locus_tag="L1U99_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBN1211308.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(11208..11642)
                     /locus_tag="L1U99_000746"
     CDS             complement(11208..11642)
                     /locus_tag="L1U99_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1211309.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(11742..12590)
                     /locus_tag="L1U99_000747"
     CDS             complement(11742..12590)
                     /locus_tag="L1U99_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1211310.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            12979..14745
                     /locus_tag="L1U99_000748"
     CDS             12979..14745
                     /locus_tag="L1U99_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBN1211311.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            14847..16106
                     /locus_tag="L1U99_000749"
     CDS             14847..16106
                     /locus_tag="L1U99_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBN1211312.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            16253..17554
                     /locus_tag="L1U99_000750"
     CDS             16253..17554
                     /locus_tag="L1U99_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1211313.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            17557..18408
                     /locus_tag="L1U99_000751"
     CDS             17557..18408
                     /locus_tag="L1U99_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1211314.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            18421..19236
                     /locus_tag="L1U99_000752"
     CDS             18421..19236
                     /locus_tag="L1U99_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HBN1211315.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            19387..20553
                     /locus_tag="L1U99_000753"
     CDS             19387..20553
                     /locus_tag="L1U99_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1211316.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            20783..21430
                     /locus_tag="L1U99_000754"
     CDS             20783..21430
                     /locus_tag="L1U99_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBN1211317.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            21514..22458
                     /locus_tag="L1U99_000755"
     CDS             21514..22458
                     /locus_tag="L1U99_000755"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HBN1211318.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            22593..24044
                     /locus_tag="L1U99_000756"
     CDS             22593..24044
                     /locus_tag="L1U99_000756"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HBN1211319.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            24065..24901
                     /locus_tag="L1U99_000757"
     CDS             24065..24901
                     /locus_tag="L1U99_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBN1211320.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            24901..25560
                     /locus_tag="L1U99_000758"
     CDS             24901..25560
                     /locus_tag="L1U99_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBN1211321.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            25686..26375
                     /locus_tag="L1U99_000759"
     CDS             25686..26375
                     /locus_tag="L1U99_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211322.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            26381..27337
                     /locus_tag="L1U99_000760"
     CDS             26381..27337
                     /locus_tag="L1U99_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HBN1211323.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            27381..27893
                     /locus_tag="L1U99_000761"
     CDS             27381..27893
                     /locus_tag="L1U99_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1211324.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(28149..28697)
                     /locus_tag="L1U99_000762"
     CDS             complement(28149..28697)
                     /locus_tag="L1U99_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1211325.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(28786..29967)
                     /locus_tag="L1U99_000763"
     CDS             complement(28786..29967)
                     /locus_tag="L1U99_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBN1211326.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(30203..31711)
                     /locus_tag="L1U99_000764"
     CDS             complement(30203..31711)
                     /locus_tag="L1U99_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBN1211327.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            31870..32061
                     /locus_tag="L1U99_000765"
     CDS             31870..32061
                     /locus_tag="L1U99_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211328.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            32264..33181
                     /locus_tag="L1U99_000766"
     CDS             32264..33181
                     /locus_tag="L1U99_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HBN1211329.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            33174..34247
                     /locus_tag="L1U99_000767"
     CDS             33174..34247
                     /locus_tag="L1U99_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211330.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            34395..34913
                     /locus_tag="L1U99_000768"
     CDS             34395..34913
                     /locus_tag="L1U99_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211331.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            34894..35286
                     /locus_tag="L1U99_000769"
     CDS             34894..35286
                     /locus_tag="L1U99_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HBN1211332.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            35362..36297
                     /locus_tag="L1U99_000770"
     CDS             35362..36297
                     /locus_tag="L1U99_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HBN1211333.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            36430..37209
                     /locus_tag="L1U99_000771"
     CDS             36430..37209
                     /locus_tag="L1U99_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBN1211334.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            37202..37519
                     /locus_tag="L1U99_000772"
     CDS             37202..37519
                     /locus_tag="L1U99_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBN1211335.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            37763..39373
                     /locus_tag="L1U99_000773"
     CDS             37763..39373
                     /locus_tag="L1U99_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBN1211336.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            39530..40378
                     /locus_tag="L1U99_000774"
     CDS             39530..40378
                     /locus_tag="L1U99_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBN1211337.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            40609..41088
                     /locus_tag="L1U99_000775"
     CDS             40609..41088
                     /locus_tag="L1U99_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211338.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            41121..43349
                     /locus_tag="L1U99_000776"
     CDS             41121..43349
                     /locus_tag="L1U99_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1211339.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            43478..45121
                     /locus_tag="L1U99_000777"
     CDS             43478..45121
                     /locus_tag="L1U99_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBN1211340.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(45194..45739)
                     /locus_tag="L1U99_000778"
     CDS             complement(45194..45739)
                     /locus_tag="L1U99_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HBN1211341.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(45762..46247)
                     /locus_tag="L1U99_000779"
     CDS             complement(45762..46247)
                     /locus_tag="L1U99_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBN1211342.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(46237..47049)
                     /locus_tag="L1U99_000780"
     CDS             complement(46237..47049)
                     /locus_tag="L1U99_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HBN1211343.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(47188..>48297)
                     /locus_tag="L1U99_000781"
     CDS             complement(47188..>48297)
                     /locus_tag="L1U99_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBN1211344.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        15895 a         8765 c         9362 g        14275 t
ORIGIN      
        1 tcttgtcacc atcctttttt ccgctctctg actttttaca atcttcatag ctcaagtgcg
       61 catcagataa tcgaatgctc ctaaagctgc agtagctcct gaacccattg aaacaatgat
      121 ttgtttgtat ggactatctg tacaatcacc agctgcgaaa acgccgggga tattcgttgc
      181 gccatttttc tcggtcacta tttcatttct tggattcatt tcgatcgttc catctagcca
      241 atccgtatta gggagtaagc cgactagaat gaatactcct gaaacagcta gtgtatgcat
      301 ctccatcgta cggcgatcga tataggagag agattctacc tgattcgtac cgctgatttc
      361 tttcgtcgct gcatgtttga taacagtgac attcgcaaga gagactagtt tatcctgtaa
      421 gatttgatct gcttttaatt ctggtaagaa ttctagaaca tatacatgtt ttgctaaccc
      481 agccaaatcg attgctgctt caacaccaga attaccacca ccgataacag caatctcttt
      541 tcctttaaat aaagggccgt cacagtgtgg gcaataagca attcctttat ttttaaactc
      601 tttttcgcct ggtacattga tagaacgcca gtgcgcacct gtcgcgatga tggcggtttt
      661 tgctttaagt gatataccgt tagctaagcc aatattaata aaatgttgct ctttatttaa
      721 ggaaacggcc tgttgattca tcataatgtc gatagggtaa ctacgcacat gactttctac
      781 ttgctgcatc aattttggac cttctgtgta agaggtacca atcatatttt caatccctag
      841 tgtttcaacg acttgtccgc cgaaagaatc agcgacaagt cctgtacgga ttcctttacg
      901 tgctgcatag atagctgcac tactagctgc tggtccaccg ccaatcacta atacatcata
      961 aggttctttt tcaaacaact cttcttcaat caaagggcca gtgatttttt caacaatttg
     1021 ttcgatcgtc atgcgtccgc tactaaattc ttctccattt aaaaacacag ttggcactgc
     1081 catgattttt ttatcatcga tttctttttg gaacatccca ccttcaatca tcgtatgagt
     1141 aatatttgga tttaatacag ctaatatatt caatgcctgt acaacgtcgg ggcaattatg
     1201 acaagtcaag ctaacataac tgtcaaaatg caatgtttgt gttatttttt tgattttaag
     1261 actcaaagat tcactgattt tcggtgcccg tccactaatt tgtaacatag ccagtaaaaa
     1321 agaggaaaat tcatgaccga gggggatacc agcaaaaacg attccacttt ctttgccaac
     1381 tggattgata gaaaaactag gtgtgcgcat cgaatctctt ttttcccaag agattttagg
     1441 agacatttct gctatttcct tcgtaaattc agctagtttt tgactatttt cactattatc
     1501 caaactaaca gaaaaaacaa taggagattc aatcagtgct aaatattgtt cgagattttg
     1561 tttagtttct ttgtctaaca tatccaccac ctaaatcttt ccaacaagat caaaacttgg
     1621 tttcaatgtt tcgccacttt ctttccattt tgccggacaa acttcacctg ggtgggtacg
     1681 tacatattga gcagcgcgaa tcttatcaat cagtgcacta gcgtcacgac cgattccatc
     1741 tgcattgatt tccatagctt gaacgattcc gtctggatca ataataaatg ttcctcgctg
     1801 agctaatcct tgctcttcat ccaaaacatc aaaaatacga gaaatctgat gagacggatc
     1861 accgatcatc acgtattcga ttttaccgat agcatctgat gtatcatgcc atgctttgtg
     1921 agtaaagtgg gtatcggtag agcaagaaaa gacttcaaca cctaaagatt tcaatgtact
     1981 gtattgttct tgtaagtctt ctaattcagt aggacaaaca aaagtaaaat cagctggata
     2041 gaagcaaaga atactccagt tccccataag atctttttca ctgacttcta aaaattctcc
     2101 ttgatgataa gcatgtgcat taaattcttc gatttttttc ccaatcaatg acatagtaaa
     2161 acctccaata ataattattt atttataatt attgtaattt agttggagtt gcaaagtcaa
     2221 tggatatttt gttatttaat aaagattact caaaaacgaa ggttaattat aaaaatagaa
     2281 gaggtcgcaa gaaaatgcta ctgctggaaa tactcgggat aacgttgagt aacagtttcc
     2341 tgttctttca gcatcatgtg taagtgcaat cccgtttgaa atcgagcttc ttctggtttt
     2401 ttatcaacta aagccttgag taaatcataa tgttgttcca tgatcgtttc ccatggaagc
     2461 ccctgaatgg tcactcgtaa ccagcggaaa cgttctaaat gggtattatg gtcatctaac
     2521 cagttccaaa cttcttttct tcctgcaatt tcgaaacaag cttcatgaaa taaattatct
     2581 gcacggaaaa aagcgcgttc gtcatttatt ttgactgctt tttcttgttc ttctaaaatc
     2641 gtttctagca ctattcgtgt ttgtgtgtcc aatttggaac aacattcaat catgatttgc
     2701 tcttccaact gttctcggac aaagcgagca ttttctgcag aaacaagatt aattttggaa
     2761 acatacgtac cactttgagg tatcgtatac acgagttctt gctgacgtag ttgaatcaat
     2821 gcttcgcgaa tgggagtccg gccgatagca agatgttcct ccagtgcctt ttcagatatt
     2881 ttccttccag gttctaagtc agcatagata atttgtttac gaatcgcttg ataagcttgt
     2941 gattgcaagc tgcttttcat ctttattcct ccaaaatcat ttctatgaac gtagtataac
     3001 agaagaggtc tgaaaaacaa tctggtatgt cacattaact agtaaatttg tataaatagt
     3061 aaaattttgg ttgacatagc gatttttatt gcataaaatt cacttgaata caaaaactaa
     3121 tatgttagtt taggagggga aaaatgattg atttaaacaa ctggaggaac tttatccctg
     3181 aattatctca aaaagaagta gaaatacctc attttgaccg tgcatcatta agagaaaatg
     3241 gacaaaaaaa tcctgtctgg atccatttcg gtggcggaaa tctttatcga ggatttcatg
     3301 cagaaatcgc tcaacgttta gcggatctag gcgaattgtc cactggtgtc attgtttgtg
     3361 aaacattcga tgaagaaata attgaaaggg cttaccaaga ttttgatgat ttgattcttg
     3421 aagtggtcat gccaagcagt ggagagttcg tcaaacgtat attagctgcg acagctgaca
     3481 gtctgtattg tcatccagat tgttctgaac actttgataa gatgattcga cactttgaaa
     3541 atcctagttt acaattagtt acttttgcta ttactgaaaa aggttatcga ttgaaagata
     3601 caaataataa atatatagga ccgattgcag tcgatataaa aaatggtcca aagaagccat
     3661 cacatacaat gagtattctt gctgtgctac tttataaacg ttttttatct ggagcttggc
     3721 cgattgcact tgtctctaca gataattttt cacaaaacgg tagtcaatta cgtacttctt
     3781 tgctaacgat cgcaaaagaa tggcaaaagg aaggttatgt acaaaataca tttatccaat
     3841 acttatcgaa tgaagaaatt gttgcgtttc catggacgat gattgatcgt atcaccccga
     3901 atccttcctt gtcagttagc aaaatgttgg caaaagaggg cttttcaaat atgtcgattt
     3961 tccaaaccgc aaaaggaaat aatattgctc catttgtcaa tacagaggac atccattatt
     4021 taatcatgga agatcatttt cccaatggac gtccgaaatt cgaaaaagct ggggtattct
     4081 tgactgatcg tgcaacggta gataaagcag atacgatgaa ggtgacgact tgccttaatc
     4141 ctttgcatac gtctttagct attatgggtt gtttactggg gtataggagc atagctgagg
     4201 agatgaaaga tccagattta tcgctgctag tttctgaaat cgggtacaat gaaggcctcc
     4261 cagttgtgga gtctccaggt atcattgatc caaagatctt tctggaagaa gtaattactg
     4321 tgcgcttttc taatccaaat attcctaata tgcctcagcg aatcgccacg gatacctctc
     4381 aaaaggtggc gattcgttat ggtgagacga ttaaaaaata tatggaaata gaagttaaag
     4441 acccgcagac acttgtattc ataccattga ctctcgctgc ttggcttcga taccttattg
     4501 gcattgatga tcaaggaaaa ccattcatcc cgagtccaga cccactattg acagaccttc
     4561 agcataagct ttccgatatt caactgggta cgcaagatac atcacatatt catgagaaaa
     4621 tggctcctat tttgtcaaat aaagaaattt ttggtgtaga tctttaccaa gcagagcttg
     4681 gcagaaaaat agaagaaatg ttcatcaaga tggtagcagg accaaatgcc gtacgaaaaa
     4741 cattacagga ttacttacaa gaacatggag gaaatttatc atggaaatga cttttagatg
     4801 gtacggatca caggaagaaa agattacctt agatgaaatc agacagattc ctgcggtcaa
     4861 agggattgta ggcacattga tggatatacc agtaggagag gtatggccta gggagaggat
     4921 caaagaacta aaagaagaaa ttgagtctcg tgggttaaca ctaaaagtaa ttgaaagcgt
     4981 caatgtgcat gatgccatta aaattggatt accttcccgt gagcagtata tcgaaaacta
     5041 taagcagaca atccgaaact tggcagaata tggaatagaa gtcatctgct ataattttat
     5101 gcctgtattt gactgggtga aatctgacct tgactaccgc ttagaagacg gctcatccac
     5161 gttagctttt atatctgatg atattccaga tgatccaaga gaaatcgtcg cgcgcatcga
     5221 acattccagc aatgaatttg gattgccggg atgggaacct gagcgcttag ctcctatcaa
     5281 atccttgctt gaagcctatg catcagtaga cgaagaaaaa cttcgagaaa attttgccta
     5341 ttttctccaa tcaatcatcc caacatgtga agaggtaggg gtcaaaatgg ctgtacatcc
     5401 agatgatccg ccatactcga tttttggatt agctcgaatc gtaaagaatc gagaagattt
     5461 agattggttg tgtcgcatag tagacagccc ttataacgga atcactcttt gtacagggag
     5521 tattgcagaa gatccagaaa atgatgtata tgggatttta gcagaatttt gccaaagaga
     5581 tcgaatccca tttgcacatg ttcgaaatat taaattttta gctaatcgag atttctatga
     5641 ggcaccacat aaatccgaat acggttcatt agacatgtac cgcatactaa aaacaatgta
     5701 tgacaacgga tttaacggat acatccgtcc tgatcatgga agaatgatct ggaatgagac
     5761 aggaagacca ggatacggct tatatgatcg agcattaggt gctgtttatc taaatggatt
     5821 atgggaagca atcgaaaaag gaaacaaaag taaagataat tagtgaaaaa aactgtaatt
     5881 ttattatgta aataagaagg atgttcaaat tcttgataca taaatccgga ggttgttaat
     5941 aagcattcgg atttatgtat cttatttggt ctaggaagta acttgatttt cttttttcga
     6001 ttgatccatg agtgcttctt cttttaattc aaagatatat tctgagatcc tcataatcac
     6061 ttttttccag tcttctggtg tgatgattcc ttttaaaata tagatttttt tgatatgaga
     6121 aggcaattgt ttcaaagggc agtcgctgat aacgatgttg cagttctcca taaaatcatt
     6181 ttgtattttg atcgattcat ttgaaaaaat ttgttctatc ttaacgatca gatctttact
     6241 gatataaaaa tcacgcgtat agttcacacc aatcacaatt cgcggctgtt ttttgtagcg
     6301 atcatacaaa tgtactaggt cttcaaccat ccattgcaca ttttcctttt ctaaaataac
     6361 tggtaacaag tgttgatttt gttctctgaa atccatataa aattgttcaa tggcggtttg
     6421 gacttctttc aatacgctat gttcttgata aagcatgaaa gtaggaaggg gcgtatttgg
     6481 ttgattgaag ttaagaaatc cattataaag tttatttcgt gcgaatgcca atgagtaaag
     6541 aatcttttct ttttcaggta taaacaaatc aaatacagta caaagggact ccaccatttc
     6601 tcttgaataa agaacatgag gaacgtttgc tttttttaaa agtttgtatt gctccaagct
     6661 tgtttcttcc gattcgattt tcgtgataga aagtcgagct aaaatattca ctaagatgcg
     6721 ttgttcgcga caaattggca gattaggtcg caaaatatct acagagagat caataaaaaa
     6781 gtcaatatat tcatactctg tgaattcttt ttgtacgtct ttcacagaag ttgcaggaaa
     6841 attctcttta catattttta atagaaaata taatttatct atcataccgc tatttagtcg
     6901 gtcaagtact tcttttttaa aaaaagtatt catcataaaa gccactactt gcggatcttc
     6961 atcataaaat tctgtagcag tacttgaaaa gatgttccaa taaatatcta atgctgcata
     7021 ttgaatttgt acctcttttc cagaaaaaga ctttctgcca ttattagaaa aggagataga
     7081 caaaccgtac tatgctaaaa atgcattaat ctttttcatt ttcgtataca aataagaggc
     7141 actatagttt gtttgctgac tgaaactgat aatcgaattt gtctgacagc tgaacaaaga
     7201 agtcaagatc tgataactga ctgattcgtt gcagtatctt ccaaatagac gataatagca
     7261 gtaagccgga tcaattcctt caaaattcaa ctttaaaaaa ggtttttgct tatcaatatg
     7321 cagttctgtt agattgagac gctcaaagtc ttgttctaat tctttgatgt atagtaaaaa
     7381 atttgattca gacatatgga aatgatctgc taaatattgt gtagtaataa agaaacgatg
     7441 ttcagatagg aaaagaaaaa tatctaattt tgtattgctt tttttcttca agataaacgt
     7501 tttaatcgct tcttgagttt gcatgaaaga ggctcctttt tacttaaatt gttaaaactt
     7561 gaaaatatta ctgttttttt cataaattta gacaaaaaaa cagtaaacat ataggtagaa
     7621 tctctactat cttatttctt gcatacaaaa aaatcaagga gtgagagagt tatgagatat
     7681 tcaaccatct taatatcaac atttgcagcc ttaagcttat cgcttactat aaatcagaca
     7741 gtccacacag aggagacaga aacagccaaa tggacagaaa ccaagtgggc caacgtcaat
     7801 cgaattacct ttcaggatga attttcatcc ttcaattcag gagtcgcaaa attaagaaaa
     7861 ggacaaacag cgaccatcaa agcaaaaatt gactattcgg gagacttagc acctatacta
     7921 caatcagctg ttacatttga gaatgttgat cccactttgt cgattggcta tgacgagaac
     7981 actttgacta tccaacacaa gcaagcgata tttaccttca ccgttacatt aaatcaggac
     8041 ttgttaaaac cagcgctttt tactgtcaag gtatcagatg gactaccgaa cgatcatcat
     8101 ttaacgccgt atagtcagcg gcagacaatt gagcaagatt cagccatcga ctcaggagga
     8161 gatcttgttg aagaaccaac agataaacca gaaaatgaaa ataagccaga agtaccgcct
     8221 acagaaaatc cagacggaga acagaaaccg gaaatagaac ctggagaaga acccgataca
     8281 gaaactcaac cagagccaga caataaatca aaacctgaaa taacccctgg agaaaaacca
     8341 gatgtaactc cagaaccaga tacggattct ggaaaccaaa cagtaccgga aacaaatcca
     8401 gacacagata atgaaactga aaatccagaa aaaccagagg tagatccaga agaaaaacca
     8461 gatgtgactc cagaaccaga tacggacgca agagaccaag gaataccaga aaaaataaac
     8521 aaaaaaacaa ttcaagagga tggaaaaaaa gagagtaaaa aatcaaatct agcaattcta
     8581 aaaataaatg aagagcagct gaataaaaaa tcacgaatat ttgatagcgc ccaatcagct
     8641 gaaaccttaa aaagtagcaa ggatacaacc tttgctgtcc tgaaacgaaa aataaacagc
     8701 taccaaaatc cggagagtca caaaacaaag ttatactgtg gagcggaatc attctattaa
     8761 gtatagcaac aatgctttct gcaaaaagat ttaaacaaaa cagatctctc taacatttga
     8821 ataatgtctg tgaacgcatt tttcaaataa aaagaaatat ccagaaaatg accccaaaat
     8881 accagattga aatctgatat ttggggtcgt tcatacttta tctttcttca tatttatttt
     8941 aagggatatc tgtttctttt ggaagatggt tcgggatctt tttcactttc aatacatcta
     9001 aaaagaaggt aaagatcgga atgccgacaa tcaagcccca aacgccaaag aaccgttcgc
     9061 taacaagtaa gaccacaaat gtataaaaaa tcggcagttc tgttttgctg gacatcaact
     9121 tcggattcag cacataagac tcaattagat ggacaatcaa aatcgtaatc aggatataaa
     9181 caacatctcg gatgcctcct tgggaataag ctatgaaaga tagaggaata caagaaatga
     9241 taacacctgc tactgggatc agacttaaaa tgaaaatcat gatcgctaaa ctcagcagct
     9301 gatgaaagcc aaatacagcc aaggcgattg tagtgagcaa cgtatttaaa agagcgacaa
     9361 caaattgagc ttctaatacc aaaccaaatg tattgacaaa cttatcggca aaatagtaaa
     9421 tatcttgaaa gaaccaagaa aattcacttt ttaaaaacaa tcttgagaat acaattgttt
     9481 ttttcttttc aatcataaaa aagaaactta agatgaatga catagcaaac gccactgcca
     9541 tttttcctat atcctgtaaa tagccaagcg caatcgaagc gccattttga agctgttcaa
     9601 aaaaatcgtt tcgctcaata taagtatgga tatattgtaa aacaggatct gcatcttttg
     9661 gctgatgctc gtaaaaatta ataacggact ggatcatgtc aaatgtttga tgaataagca
     9721 tcgggatata ctttgtgaat gccagataga taaggtaaac gatcagtgta taaatcatga
     9781 tagctaaaac acctgtaggg attcggacaa atcgctgaat gatttgaaca agatgaatca
     9841 tcaaataagt aaagataaat gtgagcaaaa tggttgtaat catacttcta actaagaaaa
     9901 gaacaaaaac gacaaataat aaaacagtga gacggcgtat tttttcattc gccaaaaaac
     9961 gctgataaac ggtcaaatcg acaacctcca aataacaaaa aataaacacg ttattcatta
    10021 tatgatggaa tatgaaaata agaaagagca aaaagaaaaa ccgctaaatg acgttatctt
    10081 atgagttggt tttcctcata aaatcgttca tctagcagtt tcagcccttt ttctggtctt
    10141 gatgaaaatt atctagcatt tttcgggtca gatgttgcag tgtatccaat tcttcctgtt
    10201 caagtggaag ataagacttg atcttttgtg gaataccttc tgcttgtttt tgcaacgcag
    10261 caccttgagc agtcagcgta acatttacga ttctttcatc acccgtttca cgctgacgat
    10321 taatataatt tttttctgct aactttttta gtaagggagt cagcgtacca gaatccagac
    10381 acaaatcatt tcctagctct ttcactgaag tctttttctt ttcccataaa actaacatca
    10441 caagatactg ggtataggta agattcagcg gcttgaggag gggagtgtag tgtctaatga
    10501 tttctttaga ggcggcatat aaaggaaaac atacttgatt aactaaatat agatcttcca
    10561 tttttccacc tccgctgttt tactatagtg tatcatagcg gatttacaca aaaaagtcta
    10621 ttcactaact gctttcagag taacttctat atttccagct gtagcttttg aatacggaca
    10681 cactttatgc gctgcctcta ataattcttg cgtttcttcc agagaaagac cttcgataga
    10741 tccttcaatc tctacaccta agacaaagct cgtttcactt tctgaataaa gggaaacttg
    10801 tgcactgaca gtagaagccc cagagatatt tttttgctgt ttgatcaatt ctaatgcact
    10861 gttaaaacat gcactgaaac cagctgcaaa caattgttca gggttggttg cattttcgac
    10921 gcgtttacca ggagctgcaa tattcaattc gaatgtacga tcgggattat gcacttctcc
    10981 agagcgtccg cctgtgttga tcattttcgt agaatacatt tttttcataa agttaccacc
    11041 tttaattata ttttatacaa ttgaatttta cacaatataa ttgtggaaag caaagaaatg
    11101 gattggcata agataaataa gagaaagcac atgaaacaga cgcgctttct cgaatagcaa
    11161 acatatacaa aaaatatcag agacaaaaaa taatctcatc ataaacatta catatatttc
    11221 tcaaaaagtt gttttctttc ttcaaaaatt acttcacgat ggacctgatg aagcatccat
    11281 aaataaccaa aaggatctct gaacattgag ttagtcacac caaagtccat catttctgtc
    11341 atttcttgaa tctctacaca gccatttcgt aatgctttat tatgtgtgtc ctcgatatca
    11401 gagacgatga tattgaacca gatcgtattt ggatgttcag cagtaggagc agtcaaacca
    11461 agagacgtgt tttcatccag catatggaat ctcgtaccat acaaggtaaa aatgacttca
    11521 ttattgcctc tagggtaatc tgttgcctca atcagttgta tttcatcaaa gattgtttga
    11581 tacagttcta gtgctttcaa actatcattt aatacaaaat cgatttccgt tcctttatgc
    11641 ataaagatct cctctccttt tcagtcgaac agttactaga ttcttttatt ataccagcta
    11701 aagaaaacgc attcaaaaaa atagcggatt tacttaccaa ctcattcgat tggatgataa
    11761 gtaaatccgc gtcccattac ttctgctacg ctgctgacaa tgacaaaggc acttggatcg
    11821 atttcttcta tcaatggttt cattcgggaa aattcatgat cagtcacaac gatcaataaa
    11881 acctcttttg actttcgatt atacccgcct tttgcctcta gcagggtaag gccacgtcca
    11941 atctcagcac ttaagcgaag gcggatgtct tccaaataat gttcactcat gaccataaca
    12001 gatttctttc gattgatacc tgtttcgata taagtcatga caattgaagt gattgcaata
    12061 gataaaatag cataaagaaa ctcttctatt ccaaaaataa acagattaag agaaacaacg
    12121 aatgcgtctg taaaaaataa gccaatcgaa gtattcaagt ggaaatattt tttaaaaatg
    12181 aggggaggga tcgtcgtacc gccgctagaa gagttgtttt tatataaaat cgcaactcct
    12241 aaagcaaaaa tcgcacttcc aaaaatgaca gacaacaacc gatctgaagt aatcattgtt
    12301 tctggaacta ttgcaatgat taaaggaaaa accaagcttc cgaaaagtac tttaaaaaag
    12361 ggttttttac ctaaaaatag aagagctagt accaacataa cgatattcaa cactaaaata
    12421 actatagctc ggtcaaagcc taaagcagct tccagtaata ttcctagacc gctgacacct
    12481 ccagcagcaa tatgatgagg ccctaaaaac atattgatag cgactcctaa tatgaagagg
    12541 gcaaaaataa tcttaatgta tgtccatata aattgtctcg tttctttcat ttattcactt
    12601 ccttaattca ttaataatac tcttatctta ttataactta cttttcacct taagttaact
    12661 ttaattaata aaaaaattag gctagtctaa attattatgt ttcattcttc tagaatatac
    12721 ttctacgcca aaaactgtta aaaaactttt actttagaaa attggagaaa ttgatcgctt
    12781 aagataaatt caggacacta aatagtacag gaagtagact aaaactttta aaagttttaa
    12841 gtctatctat ttggcaagtt taaaaaataa aaattcggta tcaaaaaact gttaccgata
    12901 acatttttga aagcgttgtc ttttgcttct ctatcactta tagtgatgac gtcatattaa
    12961 aacacaagga ggaaatcaat ggatacagct gcaatttatc atcgaccgga aagtgaatat
    13021 gcatttctat atacgaatac aagatttcgt attcggcttc gtactaggaa aaatgatatc
    13081 aaaaaagtat atgtgctatg tggagatcca tataccataa caactgaaaa atggtatcaa
    13141 aaacaacgac caatgaaaaa atgtctaagt accaatgttc atgattattg ggaaattgaa
    13201 gtgacgagcg aaacaagtcg cttacagtat gcgttccatg ttgttgggga agataacacg
    13261 gactgttttt acggtgatca aggaattttt ccttatcgag aaaatgtgat tactgaacca
    13321 aatttttatt ttcgaatacc ttattttcat caaatcgatc gattcactat tccagaatgg
    13381 gtaaaagaaa cagtatggta tcaaattttt cccgaaagat ttgcaaacgg ggacaaagca
    13441 aatgaccccg aacacacttt accttgggga agtaaagatc cagaccgaga agactttttc
    13501 gggggagatt tgcaaggtgt gatggatcat ttggattact tgacggacct tggcatcaat
    13561 ggcatctatt tttgtcccat atttaaagcc acatccaatc ataaatacga tacgattgat
    13621 tattatgagg tggatcccgc ttttggcgat aaaaaacttt taaaaaactt gattgatgaa
    13681 gcacataaaa gagggatacg tatcatgttc gatgctgtat tcaatcatat gggtgtccat
    13741 tcaccacagt ggcaagacgt tctcaaaaac ggagaaaaat cgatctataa agactggttc
    13801 cacatccgtt ttttcccagt agattcttat cagatgactg acttaccaga aactgctgaa
    13861 aatatcccat atgatacttt tgcttttact ccattcatgc cgaaactaaa tacagcaaat
    13921 ccagaagtgc aaaaatattt gctggatatc gcaacttatt ggataaaaga attcgatatt
    13981 gatggatggc gtcttgatgt tgctaatgaa gtcgatcatc atttttggaa aaaattcaga
    14041 gaagcagtta cagaaatcaa accagacatc tatatccttg gagagatttg gcattcctct
    14101 caagcttggc tgcaagggga tgaattccat gcagtgatga attatgcatt tacagattcg
    14161 attaaagatt attttgcaaa aaagaaaatc acagcttcac aaatggtcag tggaatgaat
    14221 catcagcaaa tgctttacag agatcaggtg aacgaaggaa cattcaactt attagattct
    14281 catgatactg ccaggatctt gaccctttgc caaggtaaca aagaattgat gaagtctgtg
    14341 atggccttta tgtttcttca aaaagggtct ccttgtatct attacgggac agaaataggg
    14401 atgactggtg aagatgaccc ggattgccgc aaatgtatga tatgggagaa ggaggaacaa
    14461 gatctagagc tattcggttt tataaaagaa cttgtttctc taaggaaaca gttgtctaag
    14521 attatttctg aaggttctac tcagtggcta atagtaaatg atcgtgaaga taagctctat
    14581 ttcacacgga aactagaggg acagatcatc tatgtttact ttaatcagtc aaaagaacct
    14641 tgggtagtag aacaggaaaa tgaggtgatt cttagtcaaa attgtcagtt gttagaagac
    14701 gggaaagcag agatacgaca atacggattt ttgatcatgt gttgaaaact gttaccggta
    14761 acaacaagaa agcgtttgca aatgaagatt tgtgcccatt ataataaggg tgtaacagca
    14821 cgttgaatac aaaggaggaa atgaagatga aaaaaagaag tgtgaaacag ttgggtttag
    14881 ggttaatctc tttaggaatc ttaggcggat tagcggcttg tggcaatggt aactcttcag
    14941 cagaagggga agccgatgaa ggaaaaacgt taacagtttc cgttgattct ggatataaag
    15001 attatataaa cgaaataaaa aacactttcg aaaaagaaaa cgatgtgaaa atcaagctag
    15061 tagaaaagga catgttcgat cagttggaat cattagcgtt agatgggcct gctggaaagg
    15121 gacctgacgt tatgatggca gcatatgacc ggatcggtgc gttaggacag caaggacatc
    15181 tggcggaagt aaaactggga aatgaagcag cttacgatga aacagacaaa gcccaagtga
    15241 cttatgatgg aaaaatctac ggagaacctg cagtaatcga gacccttgtt ttgtactata
    15301 acaaagattt agtcgataca gcaccatcaa cgtttaaaga tttggagaat ctatccaaag
    15361 acagtcgttt tgcttttgag tcagaagcag gaaaaaatac aggattttta gctaaatgga
    15421 ctgactttta ttattcctat ggtttaattg caggttacgg tggctatgta tttggtgatg
    15481 atggcacaaa tccttcagat atcggtttga ataatgcagg tgctgtagaa ggaatctctt
    15541 atgcaacaga ttggttcaaa aatgtttggc caaagggaat gcaagacata aaaagtgcag
    15601 gagacttcgc cagccagcaa ttcatgtcca ataaaactgc agcaatcatt gacggtccat
    15661 ggcaagcgca aacatacaaa gaaaacaata tcaattatgg tgtagccaaa attcctactc
    15721 taaataatgg acagccttat caaccgtttg gcggaggaaa aggatgggta gtcagcaatt
    15781 atgctaaaaa caaagacctc tctcaaaaat ggcttgatta tgtaacgaat caggaaaatc
    15841 aagaaaaatt ctttgaaatg gtaaatgaaa tccctgcaaa ccaacaagct agggaaacag
    15901 caaaggctaa aaacgatgaa ttaacaacag ctgtgattga acaatatgaa acagctcaag
    15961 cgatgccaaa catcccagaa atgggcgaag tttggacagg tgcagaaaac ttgatgttcg
    16021 atgcagcatc aggttcaaaa acaccaaaag aatccgcaga tgaagcagta aaaacaatca
    16081 gtgaagccat agaacaaaaa tactgattaa aatgataacc gtccattttt ataaaaaatg
    16141 gaacaggtgc ttcagataaa agtggcaaga gcgagatgga aaattatctt gctcttgttg
    16201 ccattatctt aaaagcagtt tgcggtttag caagtttaga gggggcattc agatgcagca
    16261 agataaaaca agcaatatca acgaaaaaaa aatcacgctt tgttcactta ttccagggat
    16321 ggggcagttt gtaaatggcc aagcttttaa aggtatcgtt tttttcgcca tattcgtcct
    16381 attcattggt cagatgcttc tgggcggatt tcatgcattg gtaggattgg ttactttggg
    16441 aagtatacca atggaagatc attcattatt tattttgatt gaaggcactt tgcaattcat
    16501 cattacaatc attttcttga ttttttacgg tttgaatctt ttagacgctt atcgagtagc
    16561 gaagatgcgt caagagggca aaaaaatcaa tcggacgatg aaggaagtca tacataatat
    16621 aggtgatgaa ggttttcctt atctattgac acttcccgct tatcttctca tgatttttac
    16681 gatcattttc ccagtcctag ttacattgtt cactgcattt actaattatg acttcaatca
    16741 tattccacca gccagtttaa ttgattgggt aggggctaaa aactttttta gtatcttctt
    16801 tttaagctca tatcgtaata ctttttttgc agtcttttcg tggaccgtga tttggacttt
    16861 atgtgcaaca actttgcaaa tcacccttgg tattctcaca gcggttgttg ctcaccagaa
    16921 atttattaaa ttcaaacgta ttttcggtat cattttctta ttaccatggg cggtcccagc
    16981 ttttattact atcatgagtt tttcgaatat attcaacgat agcgtaggtg ccatcaatac
    17041 tcaagtgatt cctttcataa accagcttcc ttttgtagat atcagtgcaa tctcttggaa
    17101 aacggacccg aactggacga aagtagcaat tatcttagtg cagggctggt taggatttcc
    17161 ctatatctat gtgatggtta caggaatctt acaatcgatt tcagaagact tatatgaagc
    17221 agcaaaaatc gacggagcaa atgcatggca gcgcttttca aacatcacgc ttcctgctgt
    17281 cttcctagtg gcagcgccaa catttattac acagtatacg gggaatttca ataatttctc
    17341 catgatctat ctgtttaaca atggcggtcc cggaagcgta ggcggaggag ctggttctac
    17401 tgatattctt atttcctgga tctataaact tacgactgga acttctccgc agtattctat
    17461 ggcttcagca atcacgttga ttatctccgt catcgttatc tgtgtgtcat tgctggtatt
    17521 taaaaagaca aatgcgttca atatggggga ttaacaatga aaaaatttca ttcgagtgct
    17581 cgattccaaa aacgactttc tcactttttt acttactttt ttcttttaat actgtcagtc
    17641 attatcatct atccgctttt gatcacagca agtactgcct tcaagtcagg aaatattgca
    17701 gcttttagtt tagatctttc aagtgactgg actttaggaa actttactcg gctattcagt
    17761 gaaacacttt acgggacttg gtataaaaat acattgatca tttctgtcct aacaatgatc
    17821 gtacaagtga ctgtagtaac tttggcgggc tatacttata gtcgctatcg ttttatcggc
    17881 cgcaaatcaa gtctgatgtt ctttttagtg attcagatgg taccgactat ggcagcattg
    17941 actgcctttt atgtcatggc tttcttatta gaagcgctcg ataagtactg gttcttgaca
    18001 atgatctata taggcggtgg aattccaatg aatacttggc tgatgaaagg atactttgac
    18061 actgtaccaa tagatttaga tgaatctgct aaacttgatg gggcagggca tttcaggatt
    18121 tttttccaga ttgtattacc gcttgtcaaa ccgatgctcg ccgttcaagc attatgggct
    18181 tttatgggac cttttgggga tttcatgtta gctaagttcc tgcttcgaac acctgaaaat
    18241 cagactgttg ctgtcggctt acaaacattt atttctgatg tgacaaacca aagagtctct
    18301 ctttttgctg ctggggcaat tttgattgca ctaccgattt gtctattatt cttcttttta
    18361 caaaagaact ttgttaccgg cctgacatct ggcggaacaa aaggatagga gcagagtatc
    18421 atgcaaacat ttccgttaaa ctatttttcc gcattacgta cgccaactca agtgtttgcg
    18481 ggacgcaaac tattatcatg gcctaaattt ttcttgatat ttgtattttt agtttccttg
    18541 atggtcatgc ctgtgactct tttttatgcc aatcagatcc aagcgattcc attagaacaa
    18601 tttctatccg ttcattcgct gatcgatgaa caaggaaccc aaaaattttc tgaacttgaa
    18661 ttatctgaaa ctgggttaca agcatcgcaa caaacgatag ctgtgacccc tgaaattttg
    18721 gtaggtgtgt ctttatctga gaaacaacaa tccgatcatg gaacttttat tgattttgag
    18781 aaggaacaat gggtgatcca acaaaaggat aaatctggta tacgccgcta tacgatgaat
    18841 tatagcccat ctttccaacc agattctgta cgtacgcccg aagatttcca acgattttta
    18901 gaaagagaat tttatgccag taatcgtcca acaatcattt tatcttatag tttaagtctt
    18961 ggtcttgtcc tatttgtcat gacgagtctc attttattcg gggcttcctt tttcttgtgg
    19021 atgacaagaa aaagccaact ttcatccatt catacattca aagagagtgc aaatttgatg
    19081 ctgaatgtta tgggaatagg ttccatggca gcagcagttg tagggtttat ccactttgac
    19141 tttatcttga tgctaagtgt ccaaacaacg ataactgtct tgctgctttt atgggttttt
    19201 gtcaaaacaa gattcaaaga taagcgtgtc gaatgacaag tttaagcgat ttatgcgaca
    19261 atgaatgtga aaaaaatgaa aaataaagta gtttttgaaa aatttctgaa aaaattaaac
    19321 ttcttagttg attcttttct tttttagtat taacgtaata gggtagtttt tttaaggagg
    19381 aaaatcatgt tagagaaaac tttatacaat caattatttt cacgttcttt ctcgctccct
    19441 gtcgaagtaa attattggga cggtacaacg aaacaatacg gagatacgga cactcctccc
    19501 caaatcaaaa tcaatatcca tgaagaaatc ccaatgaaag agattacaag taacgcatct
    19561 ttggcactag gagaagccta tatggatcat cgaatcgaga tcgagggaag tatccaagca
    19621 ttgatcaacg atgcttatca gcaagcaaac agctttttac gaggaaaaga ttatctaaaa
    19681 tggctgccaa agaaagaaaa acatacgaaa caaaaaaaca aagaagatat ccatgcgcat
    19741 tatgacttag gtaacgactt ttataaactt tggctagatc caactttgac ttattcttgt
    19801 gcttatttca atacacctga agatacgttg gaacaagcac aaatcaataa agtccatcat
    19861 atcttagaca aactctttat caaagaaggc gaaacgttgc ttgatatcgg ttgtggctgg
    19921 ggaacattga tgttcactgc taccaaagag tataatgtca aggcaactgg gatcacacta
    19981 agtgaagaac aatacgattt gattaccaaa agaataaaag aagaacattt agaagataaa
    20041 tgccgtgtat tattaatgga ttaccgcgaa ctaaaaggcg aaacgtttga tcatatcaca
    20101 agtgtaggta tgttcgaaca tgtaggttct gaaaatcttg aaggttattt caaagtggta
    20161 aaagatttat tgaaaccaaa aggaacagct ttgatccatg gaatcagccg acaacaaggc
    20221 ggtgcgacaa atgcttggat caataaatat attttccctg gcggttatgt ccctggtgtt
    20281 actgaattag ttgataatat tacaaaaaac gatttgcaac tgattgattt ggaaagctta
    20341 cgtcgtgact accaattgac attagaacat tggacaaaga attttcatca agtccaagat
    20401 caagtcacga aagaaatggg tgattccttc tatcgaatgt gggatctata tttacaagct
    20461 tgtgcagctt catttgaatc aagtaatatc gatgtgattc aatatttgct tgttcaacct
    20521 ggaaacaatg acatcccaat gcatcgtgca taattgaggc aaaagtactg tttaaagact
    20581 atttaaaaag aagctaagtt ttatgatgct ccagaagtga acttttttgt ctaacttcta
    20641 ggattgtctc taaagcttag tttctttttc tttatatttt cataataaaa gtttggttct
    20701 ttaattttta aacatgacag aaaatttttt cttcgttata cttgtaatag aatactattt
    20761 tataacaaag gggatcgaat caatgaaaaa aactgttatt tatactagtt tatttgcagc
    20821 tttgttttta gctgcttgtc aatcaaatac caatcaaggc acatctggga atacgtcttc
    20881 cagtagcgaa cagcgctctt cacaggtatc ggactcctca acaaaagcaa gcacatcttc
    20941 gtctagccag acaaaaagtt ctagtgaagc aagtactcag tcagatatca aagtgtctgc
    21001 agctcgtgcg atcgaattgt tccaagataa atacccagat actgcaatta ctagtttgga
    21061 attagatagt gattggggat cttacttcta caagatagaa ggtgtcgatg atcaaaaaga
    21121 atacgaagca agaattgatg ctcaaaatga aaaaatggag acagagaatc cagaaactct
    21181 agatcgagat gaacaaaatg gtcaaaagaa aaaagaagat ggtctggatg ttgataaatt
    21241 gatcacgatt gaggaagcag caaaaatcgc cgtcgacaaa gtaggaagcg gtacggcaac
    21301 agattgggat ttggataaag atttaggtac tacttattgg gaagtcaaag taaaagacgg
    21361 caatcaaagt acatcagtca agatcaatag ccaaacaggc gaagtactgt caactgaaca
    21421 agatgattaa gaatttcttc ggaaaacaag agttgatttt tcttttagtc atgatacact
    21481 agacaaaata acttgtttga aggagcgatt tacttgagtt tagaaacgac ctttgccaat
    21541 catatctttg ccaatccttt gatgaatgca tctggtgtcc actgcatgac tacccaggaa
    21601 ttagatgaac tggctcattc agaagcagga gcatttatca ctaagagctg tacgatcaat
    21661 gaacgaaaag gaaatcccga accacgctat tttgatgttc ctttagggag tatcaattct
    21721 atgggacttc caaacttagg tttttcttat tatctagagt atgctcttgc gtatgaaaaa
    21781 gtgcaggaaa accaaaatca accgttattt ttttccattg ccgggatgag tgtccaggaa
    21841 aacttggaaa tgcttgagaa aatagaaaaa agtgggttta atgggatcac tgaattaaat
    21901 ttatcttgtc ccaatgtgcc tggaaaacca caactagctt acgattttga ggccacttat
    21961 gaaacactga aagaagtatt cagcatcttt tctaagccgc taggaatcaa attgcctcct
    22021 tattttgatt ttgctcattt tgatcagatg gctgatatct tgaatcagtt tccattgacc
    22081 tatgtcaatg ctatcaacag tgtgggcaat ggtttgtata tcgatacaga acaagaagca
    22141 gtagtcatca aaccaaaaga agggttcggc ggcattggcg gagagtatat caagccgact
    22201 gctttggcga atgttcgcgc tttttataca cgtttgaaac cagaaatcca aatcattggt
    22261 acaggtggga ttcggacagg acaagatgca tttgaacatc tgctatgtgg cgcaagcatg
    22321 ttacagattg gtaccgagct tcataaagaa gggccggaaa ttttttctag aatcataaaa
    22381 gaattaacgc agattatgtc agaaaaagga tatacgtcaa ttgacgaatt taaaggcaaa
    22441 ttacgcacca tttcatagca aagagacgaa ggtcatgatt gatcttcgtc tttttttata
    22501 aaaaacactc gtctgttcat tcctgtgcaa gcgtactcat tgtatgttag acgaacttgt
    22561 gggaaaataa cagaggcaaa aaggaggata atatgaatga tgcaacagaa ttagcaaaag
    22621 agcttaaaga aaaagaattt agttttcaag aactagttac ggatatacag aaaaaaataa
    22681 agaagcaaaa tcatgaattg aatgcgtttg tcgcgcttga accattcgag agtaattccc
    22741 acgagctatt gattccccag tcagaaaaag ggccattggc tggtatccca tttcctttaa
    22801 aaatgctcgg tcaagaaaaa aagggatggc tagctacttc aggatctcgt ttatttgaaa
    22861 cacaccgagc ttctcataca tctaattatg tgcggcaagc agaagcgata ggtctagttc
    22921 cttttggaca aaccaatgcg ccagagtttg gtttcaaaaa tattacagac ccagtcatct
    22981 atggcccagc aagaaaccct tggaaccttg aatgtacacc gggcggatca agtggaggag
    23041 ctgctgctgc agtttcatca ggaatcgttc ctttagctgg tgctagtgat ggcggtggtt
    23101 ctattagaat acccgcttcg ttttgcggat tgattgggct gaaaccttcg cgagggacga
    23161 tgccagttgg tccatatgct tggagaggat ggcaaggagc tgctattgat ttcggcttga
    23221 cagtttctat gagagacacg gaggctttat tttatgggat gagaagtatc cattccggtg
    23281 cgccatatca agtatcgcca gttgagtggc aaacacatcc aagaaaaaaa cggttgaaga
    23341 tagctttttg tgttgattca ccgatccact cacagattag tgaagaggca gtacttgctg
    23401 taaaaaaagc tgtagatttc cttggaaaag aagggcatga tttgacagag attccttacc
    23461 cactagatgg tcgtaaactg atcacgtctt attatcagat gaatggcgca gaaacagcag
    23521 caatgatccg ctcgattgaa acaggcatcc agcgagctgt cagaaaagaa gaacttgaac
    23581 ccatttcttg gactttgttc caatatggtc agaagctctc tgccgctact tacatcgatt
    23641 ctctgcatgt atgggatgaa gcagcaattg tcatggaaaa cctacatcaa gaatacgatc
    23701 tattcctttc accaacgact gcatttaccg cccctaaaat cagcgaagat ttgcaaagtg
    23761 atgcgataag agcacagatg gaacacatca gtgattgttc tgaagtagaa ggtttagacg
    23821 ttgtttcttc catgtttgag gagagcttga agatcacacc ttatacacag ttggctaatc
    23881 tgactggaca accagcaatc agcttgccta ctcatttgac aaaagaaaac atgcctctag
    23941 gaatccaatt tatggctgcc agaggaagag aagatttgct atttcaaatc ggctatctat
    24001 ttgaagcaaa tcatcagttc catttaccaa atccatggaa atagcagaaa caaggagaag
    24061 aagaatgaag aaaaaaagat tgtttgctct aataactagt gcctttttta ttttaagcgc
    24121 ttgcggtaca gctgccgcta atcaggaaga taacagctgg agtaatgtag aaaaaaagaa
    24181 agaattagta gtagcgactt ctggcacact gtttcccgca tcttattata atgatcaaaa
    24241 tgaattagtt ggttatgatg tagatttggc aaaagaggtg gctaaacggt taaatgtcaa
    24301 aatctccttt aaagaataca acgtggatgg acaaatcact tctgtttcaa aaagagaatc
    24361 agattttgct gcgaacgatt ttggtatcac aaaagaaaga gaaaaaaaat tctccctttc
    24421 agagactttc aaatattcat ttgacagtat gatcgtacga aaaaaagatg attcaggaat
    24481 ccactcactt gaagatctta aagggaaaaa agcagctggc gaacccaata ctagctatat
    24541 gcgtttagcg gaaaaacacg gagctaaatt agtcacatat gacaatgcca cgaatgatca
    24601 gtatttaagc gatgtagcaa atggtcgaac agatgttatt ctaaatgatt attatctgca
    24661 gaaaatggcc gtatctgctt taccagatat ccctgtaaaa atactggaga acgtttattt
    24721 caatgaaaac gaaagtggtt ttttattgaa agaaggaaat gatgctctga aaaagaaaat
    24781 cgatggcgta ttaaaagaga tgaaagaaga tgggacgaca aagaaaatat ctgaaaaata
    24841 ttttcaaact gatgtttcag tcaaaccgaa agaaacgatg gctgagtcgg tgagtgagtg
    24901 atgtactttc ctctaattga tttttccctc atgtggactt cacttccttt cgtactgcaa
    24961 ggcttggtat acacattagg gattggcttc gtgtcgtttc ttttaggaaa tctggtaggg
    25021 ttgcttttga cagttttagg tcttttggat tggctgcctc tgaatgtatt tattcgtttt
    25081 tatttatcgt tctttagagg cattcccgca ctagtcctgc tgtttctgtt atattttggg
    25141 ttaccttatc aattaagtgc cttaacggct tcagtcatct gctttacgat taccagcagt
    25201 gcatttattg gtgaaatcta tcgaggatca ctagcaggcg tttcttcagg tcagtgggac
    25261 gctggtttag cttctggttt ttctttcttt ggggtattga aatatatcgt tttgccgcaa
    25321 gcttttcgaa tctcagtacc ggcactcagt aacgtagcta tggatctagt gaaaggtact
    25381 tcgttagcag caacaatcac agtgccagaa atatttcaaa aagcaaagat cataggcggt
    25441 cggacattcg attatttttc tctctatatt ttagttgcac tgatttattg ggtcatttgt
    25501 atcgggatcg aaaaagtgca acagtattta gaaaaacgtt ctatgcatca gtcaatctga
    25561 aaaatagaaa tggtgctagc gtggctggca ccatttctat tttttgtttc ttgtatattc
    25621 tgcctagtat tttaaaacca tttcatgtaa aatgtaaatc gaaaatatgt tcggaggtag
    25681 aaaacatgaa gaccccgcta accatcgaaa tagaatcctc gttataccaa tattgcatcg
    25741 agcaaggcgg cttggttgta gaagaagtca cgatgcctga tgaccaagga attgtagata
    25801 cgcttagctg cttgacaaaa tttgatggaa gccgagaatg gcgatgctat gagctgaaag
    25861 tgacaaaagc agattttcgc tctacagcca aactgtcatt tgttggacat tataattatt
    25921 ttgttttacc aagtaaacta tatgaagaag taaaaactga aatccctaca ggaataggtg
    25981 ttttagtgta tcgtccgtac acggttgaag aggagatgcc tgcctctggt acatttctga
    26041 ttgcgaaaaa agcagcaaag aaagagcttg ctgtaccgga agaagctttg acaaaccgct
    26101 tcatggcttc tttattcagg gaagtaagaa aagcaaagca aatggagcga ggcgtaaaat
    26161 attttccaac agatcaattg tacaaagaat tgaaaagacg ttcagaaaat caagatccat
    26221 tttctaacga acgatattat gaacggtttt tagaggaaat agctagtcag gcaatcaatg
    26281 agttgcaaga agaagttatc gcgcttcagc atgattatga atatttgagg caacaacagc
    26341 agatccgtcg gttgcctaca gagccattgg agtgaaaaat atgtactatc cttatttaag
    26401 aggaaaacaa tttgacctat tagcattaaa agaagcactg tcgcgaggat tgctctccaa
    26461 taaaatccaa ccagtgatcg aaccagtacg tgattccgct acgcttaaaa atgtgatcga
    26521 attatttcaa aaaaagcacc atcgaatcgc tgtgatccaa aatccccaag taggacaatt
    26581 caaattattc gatcagcatg tgcacagttg gacagtcaaa gaaaatagct ctgtcgtccc
    26641 tgcacagatc ttaacgccag aaaatctcag tgaagtactg gattcacctc cagcgtttct
    26701 tgttttcgat ggacagcact acccaaaaga tacagaggtg tggaaacagt tggcaggagt
    26761 tgattcgaaa tttttgatac cagatactag tcgctttcgc atctggctgc ccgaaaacaa
    26821 aattgtgatc cgtgactctt ttcaaacgag aaagcatgtt gaaagttatg cagataaaac
    26881 agatgacttt tttagtgatg actatctttt tttccacgca gacggatata ttggattttc
    26941 tgatttcacg atcgaaggta gccgttattt cgataaaggg ttccctagcc gagcgcttgc
    27001 tatccatcta acgtatattg atgcttacgg caatatacgc gtgaaacatt ttgtctctga
    27061 cagtaacgac tctgctaaag accaagcatt gaagtttctt gaagcaggag ataaaatgaa
    27121 aaaatggatc atgcgtcacc atcatcaact cttgattact tcaggaatga ttgaattatt
    27181 ggctctttac cagcaacaaa aattccctgg actgggagtg ttgaaaaagt ggtcacttat
    27241 gcatcatttg gaacttatta gtcacctgct agatcatcca aaagattggc ttaaatatta
    27301 ttcaaaagtt caggaactat atgaagtgat ccaatgatta gataatgtaa atgaaaaagg
    27361 aatagaaaag aggaaactgg atgtatattc ggcaaacaag gaaagaagaa gtagaagaag
    27421 tggtagaaat cattaatgcc gcagcggatt tcattgcttc gcaaggctct cctcaatggc
    27481 aaaacgggca gaaaccaaca aaagaaacga ttttgaacga tattgaaaga aaagaaagct
    27541 atgtattaat agtggaagat caaattgctg gaacagctgc attagtctca agcgtggatc
    27601 ccgtttacac aaaaatagat ggtagttgga aagaatcaac tggtccttat ttatcgattc
    27661 atcgtgtcgc tttagcagaa agtactcgag gaaaaaaact agcaaaaccg ttcttagaac
    27721 atttgttgac gattgcagcc agcaaaaata tccaagatat ccgtatcgat acttatccag
    27781 ctaatgaacc gatggaaaag accatctatt ctgctggatt cacttatcaa gggatgattg
    27841 aatttccttt tgaacacggc gaaagaaaag catatcaaat aatcatcaat tgactataaa
    27901 atcatctgag caaagataaa gacattaaca ctactgaaaa aaacaatcat atgatagcca
    27961 agaggttgta acagaagtgg ccagcttcaa aaaacaagaa agaatttccg aaaatgcttc
    28021 tcaaattttt gtggaatttt agcgtatttt acgaaatagc tgctttctga aactcccttc
    28081 atcgagaggt cgtgacatag cttttgtcac gacctctcgg cttatcctac gagtattatt
    28141 cgatacattt atatcaataa tccttttttt attttatctg cagcttcttg gaacgctcca
    28201 tcgtttgaca cgactaaaag tgaggggata gctttcaaac gtttcaactg tgctaaatct
    28261 tctacataaa ccgccagtct ggctgaaatc tgttcagatg aatctccacg ttttttcagg
    28321 cgcgattgca atgtttcttt agagatcgta ataaagatag gacggactac cgtcccgaaa
    28381 tactcatata aatgccaaaa accatttgct gtcaaaacgg cgtaacaatt tcctactgtc
    28441 agtttctttt taatttctgc tttactggaa ccatatttat gttgagcata ttggtcccac
    28501 tctgcaaact catttccctt gatcatctga ttgaatgtat tgtcagaaac aaaataataa
    28561 tcctcttgat ctttttcccc aggtcttggt gatcgattcg tgtaagtaat gatcttttgt
    28621 tccggctgaa aaatagcttc tgcgagtgaa gtttttccag aaccagaagg accgataaat
    28681 acatagcaat aattcattgt catttctcct ttgatgattg aacaagtgaa aaagctttgg
    28741 aaaatatttc caaagctttt aaaagtaact ttgctttttt gtatattata ccagcaagcc
    28801 agtcacaata gcacttaaaa agctgactaa agtcgctgtt agcaaaattt tcaatccgtg
    28861 ttttgcgaca agatttcctt tttcttcatt taatcccttc atcgcaccag aaatgatccc
    28921 gatagaagag aagttggcaa atgaaacgag gaagacagat ataattgctg ttgtacgctc
    28981 agtaaaatgg aaattaccat ttgctaattc tgtcatagca acaaattcat ttgtaaccag
    29041 tttagtcgcc atgatactac cggcatccac tgcttctttc catgggattc cgctgatgaa
    29101 ggcaagaggg gcaaagatgt aacctaggat ctcttggaaa gtgatgccga atatcccgtg
    29161 gaagatagca ttgatcatgg caatcaaagc aacaaaaccg ataagcatag cagcaaccgt
    29221 gatcgccaca tggaaaccat caagaatgta ttctcccaac atttggaaaa atgtctgttc
    29281 tttgttttct tcaatgatca gctcatcttc tttttcttct aatacatagg gatttacaat
    29341 tgaagccaga atataaccgc caaataagtt caaaacaagg gcagtgatca catatttaga
    29401 atcgatcagt gccatataag atccgacgat cgacatagaa actgtagaca tagccgatac
    29461 actcatggtg aacaaacgtt tctcagatag gaagggtaat tcctttttta tggaaataaa
    29521 aacttccgat tgtcctaaaa tagcagaagc tactccatta taagattcca atttgcccat
    29581 cccgttgatt ttacttaatc ctagaccaac agctttcata aataatggaa gaatcttgat
    29641 atagcgtaga ataccgataa tagcagaaat aaatacaatt ggcatcaata cggaaagaaa
    29701 gaaaggtgca cttcctttat ttgctacacc ggcaaaaaca aagtcaacac cttgcccagc
    29761 aaaagcaaga agatgatcaa acatttttgc caatacagaa acaaccgctg taccaaaagt
    29821 tgtacgtaat aatacgaaac caagaacaag ctgtaaaacg aacatcacaa ttagtggttt
    29881 caatttgatt gcttttttgt tactgctgat caaaaaagca agccctaatg tgacaaataa
    29941 accaataata cctaataaat aactcaaata atcactccta ttccaaattc cgttttattt
    30001 tacctgtttt gcaaataaaa tactaatctt tagtgaaatt ttcattactt ttttagagtg
    30061 aaacgcattc attttccatt agaaaataaa gcgaacaaaa taaaaggttt aaaaagtgta
    30121 acgtcttagt aaagtctata aaaaaacgaa actatcgatt aagctaatag tttcgttttc
    30181 aacatttata agtaaacttt ttctattggt aatatagatt ttcggaaggg tagacaggtg
    30241 cgcaggtaat atcgattcct agttttttca atgtttgttc atcattttta ttgaccatca
    30301 cagtagagtg ggcttgtgct ccctcaagtt cagctagttt atcataagca acttgagcga
    30361 ttggattcgt tactgcactg attgataaag cgatcaagac ttcattgatg cttagtgcat
    30421 ccaaagagga atgaagtgtc tttgatttca atccttgtat tgtttcaaga actaatggtg
    30481 acaataaagg aatgtcatct gcgatatggg ctaaatgttt tactgcattt aagataactg
    30541 ccgctgacgc atccatcaat gaacttgtac gcccggtaat gatgacttca tctggtaatt
    30601 cgattgcaat cacagcagaa ggatcttttg taggactttg cgcttgaatc ttatctgcat
    30661 agtcatgggc agggactacc acgtttcggt cttcaggacg taaaccgact tcttccataa
    30721 tcagtttgat tcgattaact gcttcttcgt cgatcaatcc ttttttgaag tcgcattctg
    30781 tttggaaata acgacggatg atttcttgtt tagaggcttc ttggacaacg gtatcatcca
    30841 cgatcccaaa tcctacacga ttcacaccca tgtcagtagg agattgataa acagattctt
    30901 taccagtaat tttttcaata atacgtttga ttacaggaaa tgtctcaaca tcccgattat
    30961 agttcacagc tactttattg taggcatcaa agtggaagga atcgatcata ttgacatctt
    31021 ttagatcgac tgtggctgct tcataagcaa tgttcagcgg atgtttcaac ggaacattcc
    31081 atactgggaa agtttcgaac ttggagtaac cagctgcatg tcctttttgg ctttcatgat
    31141 acagttggtt caaggaagta gcgagctttc cacttcctgg gccaggagct gtcactacaa
    31201 cgattggttt agttgtttca atatactcat tttttccaaa accatcttct gagacgattt
    31261 tttctacgtt gactggatag tcttcgattt ctgagtgttt atagaccttg atgtttcgtc
    31321 tttctagttt attgataaag actttcgtgg caggctgtcc actatagcga gtgataacga
    31381 cactgttgat taataagcca taaccacgta attcatcgat taaccgcaag atatccatat
    31441 cataagtaat cccataatca ccacggatct tattacgttc aatatctcca gcatagacgc
    31501 aaatcagtat ttcagcttga tctttcaatt tttgcagcaa tttgattttc gcatcttctt
    31561 caaatcctgg aagtacacgt ttcgcatgct tgtcgtcaac tagcttccca ccaaattcta
    31621 aatataattt gtcatagtgg ttcactcgtt ccaaaatata cgctgactgc tcttcaatat
    31681 atttttctga atcaaaacca atttttttca ctaggttccc tccttaagta ctaaagcatt
    31741 ttttcatttt tttgaggatt cgtcaactgg aagagcgaaa ttcctcaaaa aaacaaagaa
    31801 aatggtttaa accaacttgt ctagatagtt attcattggt atgatagttt ttgataagga
    31861 aggtgctaca tgaaaaaaag acagaaaaag aaaaacgcat ataaacacta tatccgttcg
    31921 atttttaccg gttatgaaag aatgcttgaa gatcccgaat tggaacaatt gacgtttact
    31981 tatctaaacg aagaaacgca gctaactcgt gatgagcatc agcgcattca tttcacaaca
    32041 agagatctgc ctagtaaata aaaaataaga taaaggtcat cggattcgat tctgtcctat
    32101 cagatggaaa gactagttga tcgaaaaaaa ggctgtacca aattttggtg cagcctgttt
    32161 tatggagcat tgcccgctct tttttataac aattttttac agaaaatggt actattgaag
    32221 tattaataag tgaaaaacag atgagtaaga ggaggcaagt agtatgaaag agccagatac
    32281 aaatgcaaat tatgagccag acgaactaga ggagacgaat gcggatcagg atacaggaca
    32341 agaatcgtct tctttttacg atatcaaaga aaaagcaagc atgaatcttt cccaattatt
    32401 agaagactta caggcttttg aaaaagctgt ccgcgaagaa gatatccctg agatctaccg
    32461 tttatacaat ggccgattga atgaagaatt aaaaagaagc tcaaatgaaa atcacgagat
    32521 cgatcaattg ctgatgcgta agatccatga tcgtttttta caggaatttc cttttatgga
    32581 acaagtagaa aacatctcgc caacgatgag ctattacaaa atcggcactt attaccatga
    32641 tcggcccacg gtcggtattg atgcaagtct gccagaaatt tttgttttgc ctaagatcga
    32701 tgaagagtgg gagaaatatt cccaaccgga gtcaacggac tatgacaaaa aaatcaatga
    32761 gctagacgca aaggtgatca ctgctcagac agaaattgaa cgtttagatg aacaaataaa
    32821 agaaatcaat cgacaaatga ctgatttgaa cgacaataaa ggattcttga atcgtaaaaa
    32881 aatcgaggaa gaaattcaag aattagagaa gaagaagcaa gtactatcta atgaaaaatt
    32941 aggctggctt ccttatattg agacgcctga aacaatccag cagcaaaaag aagcattgaa
    33001 gcaagaagca agagcagacc agcttcgtgc agccatcgta gaaaaagaac aaaggcaaat
    33061 cagacgctat ttcggtagca aagagggatt cggtcaagca atccatgaat tcttgatgaa
    33121 ttatcttggc aatgagaatc ctaataatca atctaatgaa ggaggttccg agtatgaatg
    33181 aacacgatga agcagaatgg acaaaaaatg aagaacaaac agaagatcat gaagaaacga
    33241 acacttcatt ggaagaacaa acaagtaatc ctctggatga cacagaagaa atccctatgc
    33301 tagaggaaac aaaaatacac gaaaaagaaa aagtaactcc gacgaatacg aatactgcag
    33361 aaaacaccca tgcttacgaa ataactgaaa atcccgggta tttagaagga aaagagcaag
    33421 atcatcaaga tatcgtcagt ttgattgaaa cagcggaagc agaattagcg gatttacgta
    33481 tgagaaaaga tttgatcgaa tcagattttc cacaattatt agaatcatat gatcgtttta
    33541 tattgaatga agaaccaatc tccacgatcg gaaagacaag cctgatcgaa tacttcacgt
    33601 atgaattact gaaaccgttg aatgatattg gtctggaacg gtcaaattca gcttatgaca
    33661 catggaaaac aagacatttt tcgatcaatt atacgttgaa tggacaaaac gaattagtct
    33721 tttcctttgt attaccgacc atcgatcaac gataccaagt ggaatcgatg agtctcctaa
    33781 acgtatcacc agagacaatg gaaatcaatg tccaagatga ccgggtgctt tctttgatcc
    33841 gacactggtc agtggatcga gtattctctg cagggcagat cacgatattc aatcacaaat
    33901 tgaatcaatt attagcccat gcaagaacac ttggttttac cgttaatcag acattactag
    33961 acaatacgaa gccacttcgt ttgaatcttc agagcgaatt tgaattgacg aatgaagtat
    34021 tggatgatat ttttatcgtg gcaatgaaaa atccatccta cgatatggaa aagatcaacg
    34081 aaactactta tcaagtacga ttagataaag gacagtcttt aacgataaca acaaacgaaa
    34141 aagatcaaac agtcttgtcg atctcatctg gagactaccc acgatctgtc attgatttct
    34201 ttatcaatta cgaattcttg gtcccattaa tggtgagaaa gtcctgattg gataagttgg
    34261 attaccagat gtcattcaga taattctgtt ccaaaggact tgcggcagtt atccagaata
    34321 attgtcacaa gtcttttctg tatgtactaa atggacgtga ataacttgct gatgaaggag
    34381 ggatttcatt aggaatgtcc acaaataaaa tagcacagct tagcttattg tctgctgctt
    34441 gtgtagcagg taggatcgct tttcaattta ttccgaattt ccagccaatg actgctattt
    34501 ttttatttat agtactttac ttaagcttaa aagatgcgtt aattgtcatg agtctttcta
    34561 ttgcgatcag cagtttttat tttggtgttg gaccatgggt catcggccaa tggatcagct
    34621 atactgttgt tctgagtttg ttttcaatcg tctgcttgag aaaaacagtg caaaggaatc
    34681 tatggttaaa gggagtctgt ttttttctgg cgggcatggt ttacggaata ggtatgaccg
    34741 tttttgatac gctgttatat cgtttgcctc aaccttggat ctattacctt caaggggtgt
    34801 cgtttgattt gatgcacagt ataggcaatg ttgtgttctt tcttgttttt ctgccagtcg
    34861 tcaaacgttt ttacaatcat tcaggaggaa aaaatgaaaa aaataattta tagtttgctt
    34921 gcaatgagtg tcagtatact cattttgaca agttgcagta caacctatac acaatcggct
    34981 tccaaccaaa aggaggaagt aaaaacatcg caaaaagcaa caatcacgtt acaagaaaat
    35041 ggtcaaaact tttcggaaaa agaagtgttc ttcaaaaaag gcgatgattt actgagtatt
    35101 ttgaaacgaa attttgaagt caaagaagat aacggcttca tcacttcgct tgaagggcac
    35161 tcacaggatg agaaaaatca actctattgg atgtttactg tggacgggaa aagtgctact
    35221 actggtgcca aagagatcaa attgaatgat ggacaatcgg tcattttcaa tttgtctaaa
    35281 ctataagttt cataaaaaac tgttaaaggg cgaatattgc cataattcag tgagttcagt
    35341 tgatgaaaga aggaaaataa catggaaaat tttaaaaaaa gcggaatgtt ttccgtaatt
    35401 gctgctctag gggctaatat tctagttgct atcagcaaat ttgtcggcta tgcaatcagt
    35461 ggcagtgccg ccatgctaaa cgaaagcatc cacagtatcg ttgattgcag caatcagatt
    35521 ttgctgttat tcggtgataa acaagccaat aaaggacaga gcgagttgca tcaatttggt
    35581 gaaggacgag caaaatactt tttcagtaca atcgtcgcaa tgatgctttt cttcggcggt
    35641 ggggcacttg gggtgatgga agcttttgaa aagttgacgc atccatccca tgaagtgggt
    35701 aatccgatca ttgttatagc aatactgtta tttggtttgg taatcgaagg aagttcgtta
    35761 cgcgtggcaa tgaaagaaat caaagaattg aatactgaaa aactttccac gatgcgcttt
    35821 ttgcgcgaaa gtcgacacag tgaaatactg attattttta cggaagactt gtgtgctgta
    35881 atcggtttgg tcttggcttt agcaggaaca atattgactt atgcaaccgg gattgctgca
    35941 tttgatgcga tcagcggatt gctgatcggt ttcttgctga tgggagccgc cattttccta
    36001 gcaaaagaat tttatagtct gatcatcggt gaaagcgtga cagcaagcga tttatcaaaa
    36061 atcaagttag cttttgaacg tcctgagatc agtcggctga tcgatataaa aacagttcat
    36121 ttaagtccaa cggagatttt agttgcagca aaagcagata tcgttggtaa caaagagaat
    36181 gaagcttact cggtcatcaa tgatattgaa aaaaatatgc gtcagtctct tcctgacaag
    36241 aagatgtata tatacattga aacagataaa tatgacccaa attattctcg taaataaaac
    36301 gtttattcat gaattgaagc aaaaatgaga aaaatataat cttgttttta aataaaacgg
    36361 ctacaattta gcgaatttat gttacaatga gtccgctgtt tatttgttgt aattaaagga
    36421 gatattttaa tgaacaaaaa gaaaagtgcg ccatggcttc aagctttgca tgcagtgatg
    36481 ccactttgta taagctatat accagtagga ttagcttgcg gagtattgtt gcaaaaagtt
    36541 ggatttgatc ctctcttatc aggactgtta tcgattctgg tcttttccgg tggcgcgcag
    36601 tttttagttg catctatgct tacgacgcaa gcatcatttg caacgacatt attgatggtt
    36661 ttctttttag aattacgcta tacattatta ggagcaagtc ttgccggttt tatgaaaaaa
    36721 gaaaagcgga cgtttttggc tgtcttttct caatcactga atgatgaaaa ctatgcggtg
    36781 aactacttaa agttttcaac tgacccttcc tggaataaaa gaaaggcttt atatgtcaat
    36841 tggttctcaa tgactgcatg ggccggtagc aatatgatcg gtaatttttt cggctcggtg
    36901 attcgagtag atgctgacct tgtccatttt gctttgacgg ccatgttcat tttcatgttt
    36961 atcatgcaga tgaaaagcgc actactgatc tttacaggtt tattctcagg cgtattaggg
    37021 gtcgtattca tggtattatt ccaaaatact ttcggattga ttgcagcaac agtcattgct
    37081 tcatttgccg gatttatgct ggagaaggca ttcaaaaaag aaaaagctaa gaaactaaga
    37141 gaccgcggta aagatgtcaa tgagccgctc ttcaacttcc cggaacagga ggccaatcac
    37201 catgactaaa ctatatttgc tacttttagt tgcttgtctg ttcatcgtgg catatatccc
    37261 gcgcttgttc ccgatgcttt attttactca tcgaaaagtg ccatcctggt tcagtgactg
    37321 gatgaaatat gtaccggtgg cattatttgc ggcgttagct tttaaagatg ttttcattac
    37381 tcatgaacat ctggatattg cttggaatat caaaatagct gcaatgattc tagtagcagg
    37441 cgtggcttac aaaacacgtt cgatggcgtt gtcagttttg acaggacttg cgtctgtctt
    37501 tttgctgtct atgctttaaa ctgttttatt ttattaaaaa cagagattgc gacataagtt
    37561 gttcaaactg atctatccga actgcatttg caacagtcaa ttctggatgc aagtttattc
    37621 gtagggataa aaaagattag tgttggctta tgatgcaagc tcttttttat tttaggaatt
    37681 agagagggat ttgtccttct atgatttttt gctataatag ggaagatgtt tattttatga
    37741 aagaatagtt gagggaattt aaatgaataa aaaattgatg caaggaacat tttggctaac
    37801 ctttgctaat cttctatgta aagttttagg ggtagtctat ttgattccct ggctaagtat
    37861 gatggggaac aatcaagatg gtatgcttgc tacgacattg tataatgttg gctatcttcc
    37921 ttatggattg ttcctgatgc ttggtacagt cggatttcca aatgcgattg caaaaaaagt
    37981 agctgtagcc acaaaagaag gagataacgc tgcttgtcgg ctgattttta gaagtacgat
    38041 caatatcatg tttgtcatcg gtatcgcctc tgctgcactg atgtatttat ttgctccttt
    38101 actagccgga atcagtccga ttgctaacgt taataatggg atactagcta tcagaagttt
    38161 atgcccatct ttgattgcta tcccaattct tagtgcaatg agaggatatt tccaaggaaa
    38221 aaatgatctg cggccttatg gaacttcttt gattatcgaa caggctgtgc gagtgatcgt
    38281 tatcttggct ggtacttatt acttgcgcgt attgactgac ggaaccatat tagaagctgt
    38341 attgatcagt acagtcgctt ctttcttcgg tgggttagct gcgattatcc atatgtatat
    38401 cgtcggacgc agaaaagact tcttcgaact taaagatttt ttgatttcca gccgttattt
    38461 cgaaagagaa aaccgatctg cctctgtctc tatcattcgg gaaacactac cgtttatttt
    38521 tgtcggctca gtcattacta tcgttcaaat gatcgaccaa gtaacgatga aaccactgct
    38581 tcactttttc cgtccagaga tcgcagatca gcaactggaa ttcttattca gccgtgcttc
    38641 tgtcaatcca aataaattga cattgatcct gatctccatg gtaggaacag tagctataag
    38701 cagcttgcca atattaagca cgatgaagaa aaaagatcgg atacaaatcg aaaaaacagt
    38761 aggagatagt ttttcgattg cgttattgat tcttcttcct tcattgactg gaatgtcttt
    38821 attagctgga ccactataca cattgttttt tggctatgat cctgaaagtg tcggatattt
    38881 ccaaatggct ttgctagctt ctttgttttt ctctttattc acgatcctat ctacgatgct
    38941 tcaatctttg aatcaccatc gttttgcgat ccgattaact gtagaagcaa ttatcctgaa
    39001 agtcatcttc caagtaatcg gattaggatt agttggcgga tacgggatga gcttatcaaa
    39061 tggcttagca ttcggtattg tctttgttcg cggctatcac tttatgtgca aagaataccg
    39121 aatagcacct ttagcaaaga tcagcaattt tttcttaaaa actttccgct ccaccctgat
    39181 tatgcttgca gtatgttttg ccgttttctt tttgctgaat cagcgattgt caatggaatc
    39241 aaaaagctat gcaatgattt attgtgtggc tgtaggaagt attggcggct tagtattttt
    39301 attttctcaa ttcggaaaaa atgggtttcg aatgttgaaa aatgttaaac atcatagcag
    39361 aagcaaagaa taggttaact aatcgttttt tgctgtcact tgaaaaacgg caactcgtat
    39421 gattacgctt gtcgtttttc tattttccaa ttttagtttc atatctaatc ttacttatga
    39481 tatagttata aggtctggaa aaattctttg aaacgaggaa attaaacaca tgaaacttgc
    39541 agtagttaca gatagttcgg catatctgcc ggaacgtatc aagaaccatc ccgacttatt
    39601 cgttattcca atccctttga ttatggatgg gaaaatttat aacgaaggaa tcgatatcga
    39661 agcggatgaa tattatggac ttttaaaaaa cagtaaagat tttcctacta cttcacaacc
    39721 tgtcgtaggg gaagttttgg gtttatatga ggaattgaaa gagaaagggt atgacacgat
    39781 tttaagtatc catctttctt cagggatttc tggctttgtc aacacattat ttgcgatgaa
    39841 agatgacatc agcggagtaa cggtcattcc ttatgactct aagatcacta gtatgccgat
    39901 gggacacatg gtagaagctg ccttagactt aaatgatgaa ggtcagtccc ttgatgaaat
    39961 acttgcacat atcgatcgaa tccgagataa tacctacgct tatctgattg tagatgattt
    40021 gaacaattta gtacgaggag gacgtttgac aaatggtgca gcgctgattg gcagcttatt
    40081 aaaaatcaaa ccgatcctga cattttctga agggaaaatt gttttattcg aaaaaatccg
    40141 ttcaagtaaa aaagcatttg ctcgagctga agaaattatt ggtagaagaa ataacgaaat
    40201 acaaccgcca gtcaaacttt acgtgataca tgcaaataat ttagaagtag cgattgcgga
    40261 gaaagagaaa ttgcagaaaa aatatccaaa tgcagaaatc gaaattggtc atttcggacc
    40321 agtcattggt acacatttag gtgaaaaagc catcggcatt gccatttcag cgcaataatt
    40381 ccttttattc aaaaaacata ccaaaaatat tccaacatca tcttggactt tctacatgtt
    40441 actaatgagc gtgtaaaaga acgagatggt gtttttattt ctatcaatga agctcttttt
    40501 ctttgcaatc ctcacttcaa tcctctataa tgtcgcatat agtttagtaa atgagtaaac
    40561 tactaattta cttatttact aaaaataaaa ggatgaggag ttaaaataat ggaaatacca
    40621 acaaatttaa aacataaacc agtaatcgtt gtagaagact atgataaagt tgatggaaga
    40681 aatgcattaa atacggatgc aaaagggctt tcactgggcc ttgctcagtg gaatgatcgt
    40741 ggaaaagtcg atatctcagg caaggtatgg cgacatactg gagaaaaatg gtcacgacag
    40801 tcggaagaat taccaatcac acgtatttta gatttagcga tcttagctgc acaaggaagt
    40861 ttatacttcc aagatgctta tcgttatgaa aaattttatg atccagaaaa tccagtcgta
    40921 gacatcattg gattacaagg gaaccgaatg acggtagaag tagataccaa aaatccaaag
    40981 atcgatgaag acatcatttt gtattacgat acactacaaa aagacggaga actgattggg
    41041 gaacgattcc gtattttaaa acgtctttta gatgagctag gatattaata gacagagatg
    41101 atcaaaaggg gaagagaagc atggagaatt tctcactaac agaaaaccga accttttcac
    41161 ggctagaaaa gcaaatgatc tggaagaaac cgaaaagcca tcggacaagt gcagaagaat
    41221 ggcggatcgc ctccgaaatc aaagggaatt ggcaagatcc tgaaatgaaa atcagtaacg
    41281 tacttttgga aggagatgcc gggtcgggga agacacaatt agccaaagca ctatctgctg
    41341 atctgcaact tccctataca aaagtgacct gttttgcaga tatggacaaa tcagatgttt
    41401 tcggagcctt attacctgta gtagattcta ataaggaaca agaccaagaa ttactagaag
    41461 ctatttacca aacagataca cttgaagctg tactgacact gatccagaac cattacggca
    41521 ttgatccttt ttctgctaaa gaaaaattag cagagctagt tcaaaggatc gaagctgatt
    41581 atccagatgc aatccattac agctattacc cttctgaaat cgttcgagcg attgaaaaag
    41641 gatatttatt agagattcaa gagccgactg tcatccgaga tgcctctgtt cttgtggcac
    41701 ttaactcagc gctcgaacca aatgggatgt tgaatttacc gacaggaatc attcgtcgcc
    41761 atccagattg cgtcattgtg atcactacaa atcgaaatta ccaaggaaat cgcccattaa
    41821 atgaatcttt aagagatcgg atgcaacatg cggaaaaaat ggatcttcct gccttagaag
    41881 tcatggcaga acgtgcgatg gcgaaaacta tgatccaaaa acaagaactt ctcttaaaga
    41941 tggcagagat tatccgtttg ttggatgaaa ctgcaaaagc taacgccatc aaaggtgtag
    42001 caggaatgcg ttcttatttt tattgggcaa atacctataa gcaaggacaa gatttactcc
    42061 agtcgattta tccaaaagtt ttgtataaat tatccactga ttcagatgaa ttggcaattc
    42121 ttgaacaagc tttgtctgac agtggattgc tactggaact tcaggacata ttgagaaaag
    42181 aaaaatgggg tcatcctcaa tctgagcata caaaaggaag aaccattagc gccgaagaag
    42241 caaatgaacg aaacatcact gaaaatgctg aagaaattct gcgcttagat gaaaagaaat
    42301 cgttgtctgc tgaagaacca aatgagggag aagagaaaca agaagaaaca atagaaaaaa
    42361 acgagattcc tcctcaaatg caaaaagaac gcagtagcga tatcgaagga aaaaatcaaa
    42421 aagaacaaca aacaggagat gattctcaag aaatgtctgc ttctgacatg gaagcacatg
    42481 ataaggaaat caagaagcaa ctgaataaag aagcgcgaca aatcatgaag gaaacgattc
    42541 atgaaaaaga aggtctcatc gttcaccgac cagctttcca aggaaaaacg ccggaagcac
    42601 gtgagctaca catgcaagta atgccaatag tagaatcact tagccggcaa attttagagt
    42661 tactggataa tgaacaaaca gagacgtacc aaaaaggaaa atacgaaggt cagcggttca
    42721 atgcaagcaa agtagcatat ggtgatttga gaaattttga caaaaagaac ccgccacatg
    42781 agcaaccttc tttagcggta gctgtacgga tcgatgaatc tgggtcaatg atacgggatg
    42841 atcggatcga agcggcaaaa aaagcagcga ttgccattgc cgaattttct aagaaagtcg
    42901 atatcccatt gttgatttac ggagatacag cagaccgttc gtcaagagaa aagacttctt
    42961 tgttttctta taaagaattt gaagacggat ttcaatggtt aaatgaaaaa ttagtcacta
    43021 tgaaaccaag gcaaaacaat cgtgatggtg ctgcacttcg tttagcagca gaaaaattaa
    43081 acagacaatc cgcaacaacc aaactgttgc ttaatattag tgacggtcag ccaaaagcgt
    43141 tgccggatta tacaggcaaa aaagcaaaag aagatatcca gtctgttttg aaagaatatg
    43201 aacgtcaagg aatcctattt gtctccgcag ctattggcca agacaaagaa gaaatcaagt
    43261 cgatctacgg tgaaagtcgt tttgtagata ttactgactt gaatgaattt cccaagcaaa
    43321 tgattcaact gattgcccgc tatctatgat aaaataaagc tcaacgaacg cacttagcag
    43381 attcgttgag cttttcgttt ctagttaccg gtaacaagga tacttctaaa atagaatcgg
    43441 ttataatcaa gagggaccgt taaaggagtg aaacgatatg atacaagaac aaaaatggtg
    43501 gaaagaagca gtaggctatc aaatctatcc tgctagtttc aaagatagca atggcgatgg
    43561 tcaaggagac atcaatggga tccgtgaaaa acttaattat ttgaaagatc ttggtatcgg
    43621 ctttatctgg atcaatccga tctatcaatc tccatttgtc gataatggtt atgacgtaag
    43681 tgactatcaa gatatagaag agagattcgg aacgatggaa gattttgatt tattgctaaa
    43741 agaagcacat gaattaggga tcaaagtgat tatggatctt gtcatcaacc atagttcgga
    43801 tcagcatcaa tggtttgaag aatcgaaaaa atctaaagaa agcccgtatc gcgattatta
    43861 catttgggtc gacggggtag atggcaaaga accgaataat tggacatcga ttttcggcgg
    43921 ttctgcttgg gagtattctc atgaaactgg acagtattat ctgcatgttt ttgcaaaaga
    43981 acaaccagac ttaaattggg aaagcgagaa attgaaagaa gaactattca atatgatccg
    44041 atggtggttg gataaaggga tagatggatt tcgtttagat gcgatttctc atgtaaaaaa
    44101 agatgaatat tcagtaaaag ccacagagaa ccctttctca ccctttcaaa atgtctcagg
    44161 aatcgaagaa catttgaccg atttgaaaca tgtttttgaa gagtacgata tcatgactgt
    44221 cggagaagca agtggtgtca ctgcagaaga aggaccacaa tgggtaggga aagacggtta
    44281 tttcgatatg atattcgaat ttgatcatat ccatatctgg cagcaagaaa aagaagggca
    44341 attagatgtc cttaaattga aacttgcatt aagcgcttgg caaacttcat tggatggtat
    44401 cggatggaac gctttatata tggaaaacca tgatgttcct cgtgccgttt cagtgtttgg
    44461 agatactcgt cccgattttt gggctatgtc tgcaaaagca atcgctatga tgtatttctt
    44521 tttgcaaggt acgccattta tttatcaagg acaggaaatc ggaatgacga atatgccctt
    44581 tgaatcgatc gatcaagttg atgcagtaga ttcgaaaaga ctttataaaa ggctgcttgc
    44641 ggaaggtaag acaagagaag aagcattgga tatcattcgt gaaacaacga gagacaacag
    44701 caggacaccc atgcaatgga cttcggaaca atatgctggt ttttctacac atgaaccttg
    44761 gctgatcact aatccaaata ccaaaacgat caatgtagaa caacaagaat atgaaccaga
    44821 gtcggtcctg caattctata agaacatgat ccgcattaga caaaccaata aaggtctgat
    44881 atacggttct tataaagaat atcttcatga acatccacaa ctttatgtct atgaaagata
    44941 tttagaagat gaacaatatc ttattatggt aaacttaaca gaatcacttg ctgactatga
    45001 acttccaaaa gaagcagatc agtcctggac attactcttg tcaaattcct ctagcggaga
    45061 atttgaagct aaaggcatac tagcacctta tgaagctcgg ttatataaaa caaacaagta
    45121 aaacttcctc gttaaagttc attagttgga ctttgcgagg aagtttttca gattgctctg
    45181 tcaattactc atttcaataa ttcgctctag gaccaccgat atatttagga cgagagcgaa
    45241 gggctgtcac gtgagcttgt ccaagggttt tcaaacgagg tctgacaggt acttggacat
    45301 gtttgatatg cataccgatt gatgtgtcac cgatatcgat accggcttgt ccaactacgt
    45361 gttccacttc gacaggatca ttgaactggt caaaagcagc aacagaacaa gcacctccag
    45421 catgtagtgc aggaacaaca gagacaattt cgaaattttt tgcttctgcc actgttcgtt
    45481 ctactactaa tgctcggttc aaatgttcac aaccttggac agctagcgca atttctttag
    45541 gatccaacaa ctcttttaac gtacggatga tccattgacc aacttccgca ctggaatttt
    45601 ttccaatatg tcctccaacg acttcgcttg tgctgcatcc taaaacaaaa agatcacctt
    45661 ttttcaagtg tgcctcagcc aatatgtcat taactatttc agtcaattgg tcttttaatt
    45721 ctttttctga caacttcatt ttctaaaacc ttctttttca attaatattg cttccgtgct
    45781 tgaatacgtt gaagacttgc agttatagga aaggcaagtc ccattccaat cagattttgg
    45841 aagatgtttc ctggtataga agccactcca gccggccaat catataaaat ccaaccggcg
    45901 ataccatagc cgatgatcat aactaagctt cctaataaaa gccctaatcc ccacatacga
    45961 gtagaagatt tgctgaaaga accagcaaca tatccttgta acccgtggat cactaatgaa
    46021 aaaactgccc actgcggata tcctgaaatc aaatcgatca atagaccact ggaagcacca
    46081 acaactaatc cacccgttgg accataaaga aaagcagcgg tatagatccc ggcctcgcat
    46141 aatgtcacaa atccattcgt agccggtaca gggatcaaaa ttgttaatga aagggcaact
    46201 gtcaacgcaa tcagcatagc atagatcgtt aattgcttag ttttcatttc tcattcctcc
    46261 tttttgaata ccgccagacc agacacttcc ggtatgatcg ttcatcagca cgccattaga
    46321 aatacaatgg gcaacaaatt ttttactttc tgctactgct ttggtaaaat ctgcccctaa
    46381 cacaagattc gctgttattg cagaagaaaa ggcacaaccg gccccgttta ctgttgtagt
    46441 gtcgattttt ttatgagaaa atacctcata atgatcaatt gaatagagaa gatccacagc
    46501 ttcatctcca gccatccttg tgccgccttt gatcacaatg ttttttgttc ctgaagcagt
    46561 gagttcttta gcgagatgga tcatttctgt taacgaagag ggaagagctt gaccagaaag
    46621 taaagcagct tctgccaaat taggcgtaat catcgtaaca agtggaaaaa gttcttcgat
    46681 gagctgcgaa atatacaatt gattgatcac agcttcagtt tctttgaatg ccaaaacagg
    46741 gtctaaaatg attgggatat tttgttttgt ttttatgaag tctcgaacaa ccatgattgc
    46801 ttcacttgaa ttcaataacc caattttgat accatctaat gaagtcattt tatcaatcga
    46861 aactaactgt cgtttaagca attccaaaga tatagattcc agcataaatc gctcattaat
    46921 atctagtgcc cctatagaag tcaaggcgct tagtccgaat agaccaaaat tctcaaaagt
    46981 ttttaaatct gtttggattc ctccaccagc aaatggatca gaaccgccaa ttgtcaagat
    47041 tcttttcata acattttcct ccatgaataa gagtataacg aaattttcaa aaaagaaaaa
    47101 cagccaattg gcatattttt atctcatcca atttaaaaaa acaaaaagaa aagaaagacc
    47161 aaaatggatc tttctttcct taaatagtta ggacttttgt gattttaatt ctttctcgat
    47221 ttgaagccgt tgcactttca ttgtagctgt tcgcgggatt gcatcaaaat cacggatgat
    47281 agggacgttc aagcgaggaa gttcatggac ttgctcccac catcgattcc aatccatttc
    47341 tttatcagga gctaaagcaa taatcggttg tggagaatga tttttatccc ttacaatcac
    47401 tacttctgcc aaaaaatcta acgaatctaa taaaaagtct tcaatagcta atgtactatt
    47461 gatcgtttcg atcaaatcca cttgccgatc tttcaaaaat aggtggccat gcttatccat
    47521 aaaaccgtaa tctccgctat cccaccaatc gccataaaca ttttcctgga accgtgcatc
    47581 ttccttgtaa taagtcaaag cccgtccttt agacagtaat tgtatatgac catctgtgtt
    47641 ttcaggtagg acattcccaa ctgaatctgt aatccgagcg cttgtcatgt cttccagtcc
    47701 aacgcccata tctcttgcat cacttgtttt caaactctct agtgtatgag ccttaagaat
    47761 cattggtccg cattcacttt ggccatatac ttgaagaaat accgcatcct gtgccatcga
    47821 cgttcgcaaa aatgtcttca ttgtctggtt gtttatagca tcaaaagtgg agtgatagta
    47881 tcggataccc gaaaaagctt ctggatgctc cttagcagta aaacgccact gaacaaagtt
    47941 attcggatgg gtctctagtg caattggccg gtgagcttcc aacatatgaa caacttttga
    48001 actttgtgcg tttgctaaag gcatcatagg aaatcccatg gacatcaaag aagagatacc
    48061 aatattgaat ctggaatgca ctggagagat gtgaaaagcg attaatttct tttccgaaat
    48121 ttttgtgaaa actgtttttt gccatttcgt ccgccatccc atagaatgag cagaatgaca
    48181 aataagttta gggataccag ttgtaccaga agtatgggtc atataagaaa tttcattttt
    48241 gtctaaaaat gattgagaaa cagacaaagc aggttgttcc attaaataaa gaatagg
//
LOCUS       DAFLVO010000013        47396 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.013, whole genome shotgun sequence.
ACCESSION   DAFLVO010000013 DAFLVO010000000
VERSION     DAFLVO010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47396
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.013"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..2327)
                     /gene="esp"
                     /locus_tag="L1U99_000782"
     CDS             complement(<1..2327)
                     /gene="esp"
                     /locus_tag="L1U99_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HBN1211345.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
     gene            complement(2944..3378)
                     /locus_tag="L1U99_000783"
     CDS             complement(2944..3378)
                     /locus_tag="L1U99_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211346.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3395..4600)
                     /locus_tag="L1U99_000784"
     CDS             complement(3395..4600)
                     /locus_tag="L1U99_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HBN1211347.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            5294..5680
                     /locus_tag="L1U99_000785"
     CDS             5294..5680
                     /locus_tag="L1U99_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1211348.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            5774..5965
                     /locus_tag="L1U99_000786"
     CDS             5774..5965
                     /locus_tag="L1U99_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1211349.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            6479..6811
                     /locus_tag="L1U99_000787"
     CDS             6479..6811
                     /locus_tag="L1U99_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1211350.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            7107..7262
                     /locus_tag="L1U99_000788"
     CDS             7107..7262
                     /locus_tag="L1U99_000788"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBN1211351.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            7538..8878
                     /locus_tag="L1U99_000789"
                     /pseudo
     CDS             7538..8878
                     /locus_tag="L1U99_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9119..10735)
                     /locus_tag="L1U99_000790"
     CDS             complement(9119..10735)
                     /locus_tag="L1U99_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBN1211352.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKKIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            10853..11071
                     /locus_tag="L1U99_000791"
     CDS             10853..11071
                     /locus_tag="L1U99_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1211353.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            11266..11727
                     /locus_tag="L1U99_000792"
     CDS             11266..11727
                     /locus_tag="L1U99_000792"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1211354.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(11920..12159)
                     /locus_tag="L1U99_000793"
     CDS             complement(11920..12159)
                     /locus_tag="L1U99_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1211355.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(12183..13706)
                     /locus_tag="L1U99_000794"
     CDS             complement(12183..13706)
                     /locus_tag="L1U99_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBN1211356.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(13724..13846)
                     /locus_tag="L1U99_000795"
     CDS             complement(13724..13846)
                     /locus_tag="L1U99_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBN1211357.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(13876..14859)
                     /locus_tag="L1U99_000796"
     CDS             complement(13876..14859)
                     /locus_tag="L1U99_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBN1211358.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(14883..15032)
                     /gene="rpmG"
                     /locus_tag="L1U99_000797"
     CDS             complement(14883..15032)
                     /gene="rpmG"
                     /locus_tag="L1U99_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBN1211359.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(15053..15430)
                     /locus_tag="L1U99_000798"
     CDS             complement(15053..15430)
                     /locus_tag="L1U99_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211360.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(15462..15641)
                     /gene="rpmF"
                     /locus_tag="L1U99_000799"
     CDS             complement(15462..15641)
                     /gene="rpmF"
                     /locus_tag="L1U99_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBN1211361.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(15656..15925)
                     /gene="rpsN"
                     /locus_tag="L1U99_000800"
     CDS             complement(15656..15925)
                     /gene="rpsN"
                     /locus_tag="L1U99_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBN1211362.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(16448..18214)
                     /locus_tag="L1U99_000801"
     CDS             complement(16448..18214)
                     /locus_tag="L1U99_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1211363.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(18174..19928)
                     /locus_tag="L1U99_000802"
     CDS             complement(18174..19928)
                     /locus_tag="L1U99_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1211364.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(20038..20607)
                     /locus_tag="L1U99_000803"
     CDS             complement(20038..20607)
                     /locus_tag="L1U99_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HBN1211365.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(20625..22040)
                     /locus_tag="L1U99_000804"
     CDS             complement(20625..22040)
                     /locus_tag="L1U99_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBN1211366.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(22051..22719)
                     /locus_tag="L1U99_000805"
     CDS             complement(22051..22719)
                     /locus_tag="L1U99_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBN1211367.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(22849..23433)
                     /locus_tag="L1U99_000806"
     CDS             complement(22849..23433)
                     /locus_tag="L1U99_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1211368.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(23764..23997)
                     /locus_tag="L1U99_000807"
     CDS             complement(23764..23997)
                     /locus_tag="L1U99_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HBN1211369.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(24012..24962)
                     /locus_tag="L1U99_000808"
     CDS             complement(24012..24962)
                     /locus_tag="L1U99_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBN1211370.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(24959..25801)
                     /locus_tag="L1U99_000809"
     CDS             complement(24959..25801)
                     /locus_tag="L1U99_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBN1211371.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(25803..26522)
                     /locus_tag="L1U99_000810"
     CDS             complement(25803..26522)
                     /locus_tag="L1U99_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBN1211372.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            27214..27372
                     /locus_tag="L1U99_000811"
     CDS             27214..27372
                     /locus_tag="L1U99_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1211373.1"
                     /translation="MNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKD
                     FMNTFKIT"
     gene            27444..28670
                     /locus_tag="L1U99_000812"
     CDS             27444..28670
                     /locus_tag="L1U99_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1211374.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(28758..29150)
                     /gene="rpsI"
                     /locus_tag="L1U99_000813"
     CDS             complement(28758..29150)
                     /gene="rpsI"
                     /locus_tag="L1U99_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBN1211375.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(29166..29609)
                     /gene="rplM"
                     /locus_tag="L1U99_000814"
     CDS             complement(29166..29609)
                     /gene="rplM"
                     /locus_tag="L1U99_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBN1211376.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(30128..30595)
                     /locus_tag="L1U99_000815"
     CDS             complement(30128..30595)
                     /locus_tag="L1U99_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HBN1211377.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(30715..32253)
                     /locus_tag="L1U99_000816"
     CDS             complement(30715..32253)
                     /locus_tag="L1U99_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HBN1211378.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            32333..33019
                     /locus_tag="L1U99_000817"
     CDS             32333..33019
                     /locus_tag="L1U99_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBN1211379.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(33220..33747)
                     /gene="msrA"
                     /locus_tag="L1U99_000818"
     CDS             complement(33220..33747)
                     /gene="msrA"
                     /locus_tag="L1U99_000818"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBN1211380.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(33831..34508)
                     /gene="pgmB"
                     /locus_tag="L1U99_000819"
     CDS             complement(33831..34508)
                     /gene="pgmB"
                     /locus_tag="L1U99_000819"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBN1211381.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(34505..35635)
                     /locus_tag="L1U99_000820"
     CDS             complement(34505..35635)
                     /locus_tag="L1U99_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBN1211382.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(35635..37818)
                     /locus_tag="L1U99_000821"
     CDS             complement(35635..37818)
                     /locus_tag="L1U99_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBN1211383.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(37815..38840)
                     /locus_tag="L1U99_000822"
     CDS             complement(37815..38840)
                     /locus_tag="L1U99_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1211384.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(38885..39712)
                     /locus_tag="L1U99_000823"
     CDS             complement(38885..39712)
                     /locus_tag="L1U99_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBN1211385.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(39709..40776)
                     /locus_tag="L1U99_000824"
     CDS             complement(39709..40776)
                     /locus_tag="L1U99_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HBN1211386.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(40802..41638)
                     /locus_tag="L1U99_000825"
     CDS             complement(40802..41638)
                     /locus_tag="L1U99_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1211387.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(41635..42504)
                     /locus_tag="L1U99_000826"
     CDS             complement(41635..42504)
                     /locus_tag="L1U99_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1211388.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(42574..43857)
                     /locus_tag="L1U99_000827"
     CDS             complement(42574..43857)
                     /locus_tag="L1U99_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBN1211389.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(43871..45556)
                     /locus_tag="L1U99_000828"
     CDS             complement(43871..45556)
                     /locus_tag="L1U99_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HBN1211390.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGTRVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            45831..46856
                     /locus_tag="L1U99_000829"
     CDS             45831..46856
                     /locus_tag="L1U99_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1211391.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
BASE COUNT        14662 a         9300 c         7514 g        15920 t
ORIGIN      
        1 cctgcggtga aggttacttt gtggtagcct gcaggaatgt tttctcctgg attttcataa
       61 atatctttac ttacagttac tgctaaatcg gtcgtgccta cagaaccatc ttggtaaaca
      121 attttaatag gaattgttcc agtaatcggc tccgattctc ctacaccttt agctggagtg
      181 aatgtaacaa taccagtgtt tgcatcaaca cttgcattac cgaagtactt attatagaca
      241 tctgaaattg aaaaggcatc tttagctaaa ggaacatctg gtttatcaaa tgtaggtttt
      301 ccactttgaa ctgtcgtttc tggagttgtt gttataggta cgtatgttgc atcattttcc
      361 atagcttgag aagcttttac agcaaactct acatccacgt cgaaagttcg atttccgatc
      421 ttaacagtta caataccttt cgtactatca gtaacgttag aagtatcagg ctctgttttc
      481 catgaatact ctgcatcttc aggtaagttt ttattattcc gaattgattc tttagcatct
      541 ggtttaaatc caactaccac ggtttgttta tcaaccgctt ttggtgattc cttaataacg
      601 gttgaacctt cttctggttt atcaaaacct ggagaaacga tttggatttt taattcatct
      661 ttcgcgatta atttacttga atctacaccc gtaaattcaa attctacagt atctgaaatt
      721 ggagccccat ctttttcatt tggagcgata gttttttctg ctaatacagt accttcttta
      781 tcaacaagtt gggctttgtg acctgttccc gctaactcgt ggatgaatac tttcccctta
      841 actgttgtgt caacatcata tacttcttct aattcaggtt tcccgatata tggattcgtg
      901 tctccgctct cttctttatc gtcagggttt ccatcaccat caatatcttg caaataataa
      961 taacctgttc cataagtgtt ctggattaat tttttattcg tatccgacaa ccaagaatca
     1021 aagatgaaat cttcaccaaa tggtttattt tcttcaactt gtgctgttgc tttcatatct
     1081 tctaagattt catctaatgg cttagtcaat tgtaaaacat atcgaataac gactggacgt
     1141 ggacttgcat tagcaaaatc gataagttta gttaaatcat tattagttat tgaacctatg
     1201 ccataatttt catgaccttc ccgtcgctcg attgctaaat cagctacttt tgttccggat
     1261 tcaaacgaaa catcatatgt tactttgtca gcctgaacca tgtgcatctg tatacccgct
     1321 acatatggaa ctaatcgttc atcaattttg taattagcat accaaggcgt gccctttgcg
     1381 gaagatgaat atgagaaatt ataatttttc gttaacttat gatctaagat tatagctcca
     1441 ttagcacctg tggatcctga accatctttt gtttgagtat taggtttctc atattttgca
     1501 cttactgatc catgtttaaa ctggtcagga ttattttcag atacatctaa gctattatag
     1561 aaatcatctg aatctgttaa aaagtagccc gtactatcaa tacccggtac aattttatca
     1621 tcgtcttgat gacttaccaa gtagattcga tacattaaac gatcggtctt gagattgtct
     1681 atgcctatct ctttaaaaat ttcatctagg ctcttttcaa acgtaattac cccattagga
     1741 gcggtttgcg tatcggttgt ttctgcccca gcaaataatc catcacttgc acgaatataa
     1801 ttgaccttcc aaatatttgt aggtctaccc agcgaatcat taattcttac aaaggtccgt
     1861 ctagaagatc caattccttt ctttggatcg acctgaattt tttctacata tttagctaat
     1921 cgttcatcta attgaagacg gatttcccag tttttagttg atgctgcaat attatgtttt
     1981 ccgtaaactt caaatccaat tgtattgcct tttagtgtgt ctccagttag ttcttgagga
     2041 ctaaattgta aatccgaaaa gttataattt ttcgtataac caggattctc ctgaaaagta
     2101 ttccccgaag ctactttgtc acctacttgt acggagctta tcgctgtttc aagtgggctg
     2161 cttggagaaa tttcatcttg tgctttaact agttcagttg ttcccaagac aagaccaaca
     2221 ccaatcaaaa cagatgcaac cccaacactt aattttttga tactgtactt caatactcgt
     2281 ttctttgttt tttctagaaa tactctctta ttattcttgc taaccattat tcaaatcaac
     2341 tcccttaata attactttcc tagtaagaat aaaagataaa tctgatacgt attattcaca
     2401 gaataggaat cttactaacc ttatgttaac taatttactt agagaatttc atgaacatta
     2461 caacaaaaaa agtacatttc ttcatgtttt tttcggatat ttgtgctttt taaccattca
     2521 gcagctgaaa acatataaaa agatatgtat gtattctttc tgaaattaag ttcatttcta
     2581 tgcgatgaag catgttttca aaatattacc ctttcttaga ttaaacttca gagtattcaa
     2641 ataacggaat aaggagcctt atcccgcatt actgaatgag actgtgacat aagtaaaaag
     2701 gtgacttcaa attccttctt cggaatttga aatcaccttc tttataatta taaagtatcg
     2761 gtttcacagc atttctgaat gattcctaga atcttaaacg aatgattgga gttatcaaca
     2821 ttttttcact cgtttttagc gaaacaaaaa atgacatttg tcacagcctc attaaattat
     2881 tgattctttt tctttataat tgaattgtcc atatttaaag tgtctagtac tctacatgaa
     2941 taattaattg ctttcactca aatacttata atctattaac ttgtagttgt ttaacttttc
     3001 tgaaaaagtt agacccacgt aataatcttc ccagctttct ctttcaatta actgatccaa
     3061 tttttgataa tccataaatt catcatgtat caaaaagaat aaataacttg atattttagc
     3121 atctagctta atcagattaa ataatgtttg tttaaaattg ctaccattaa tatgactgat
     3181 agattctcta gcttcttcac ataaactttt tactttatta attactactt tgtcatattc
     3241 atttaacaca ctattattac cattacttag acgctcagat tctacgaaac aactcaaatc
     3301 agaaatttcc caaaaaaatt ttttgttaaa atccaatttc ctcaactcct ccaaactacg
     3361 taaatgatat agtctcataa taaaataaaa cctctcagct aatgttgttg aaattgtcca
     3421 ctaaacctaa ttgatattgc ttaggagata cacctgcgta ctttttgaat actctcgaaa
     3481 agtgtgaaga atctgaaaat cctaaaccta aagaaacttc actgatagta tggtttgatt
     3541 tcaacattat tttagccgta gaaatttttc gcttagagat ataattataa atcgtaatat
     3601 gcatttcatt cttaaagctt tctcttaatt tagtttcact tacagaaaaa taattagcta
     3661 tttcctttac agtaattctt ttatagatat ttaagccgat gaattgaacg acagaagaaa
     3721 ttaagggaga aagatgctct atcttagttt ttccgatttc cttagtataa taaacaatcc
     3781 cagaatccct cacttttaag acctcaggta acgatacagc taattcgttt tcttgtatca
     3841 aagcatctct actttgatac gcttctatta tatccattcc taatgttata gacgtttgtg
     3901 ctaacttttc aaaaacaatg atagaataat ttttttcaga ccgaatcgta tctccactaa
     3961 cacttggaat tattccatta ctcagattaa aaaccatgtt ttctaaattt cgaatatctc
     4021 catttttaac atattccagt attttatttt cataaagaaa cagatatatt tctggatcgt
     4081 aattttgtga taacagatta tctattttga tttgctcgat agttttactt agattttctg
     4141 tatattcaat taacggttca tggaatagat cttctatttt tccagtaaaa aaataatgaa
     4201 ctaaaatcag aatatctcga atgtctccta aagaatacaa agtcaaattt tgcaatgaat
     4261 tatagagtcg ttctctatca gccattgcaa cattcaaatt gttcattttt agtttaaaaa
     4321 aaactttatc aatattattt gctctaaatg gaccaaataa gtaatatctg gttttaaaca
     4381 tgtatagaag aaacatctca ttaaaatcac cagtaaagaa atggaaatct ttagtttttt
     4441 taatattatc agttagtaac tttttataat cataaaaaaa ataagtagtt ctatctgagc
     4501 gatactcttt tataatactg aattcggaat taaaaaccac gataggtaac tttaaacaaa
     4561 catgaagaga ctttaataag acttctttat ctgaaaacac ttttgtttct ctctttcctt
     4621 tctacatcat taaatagtat tttatacgtt atctaaaata ctattcctct gtcaaaataa
     4681 gctaacttac ttcattataa aatatccact tatcgctttc atgtatattc caccgtaaaa
     4741 agtacatttt atcaccgaga actcatcatt tttcatcatg atgaatacta tttacatata
     4801 tctagttcaa agacaataat tattatgatc cgttattatc taagcactat acagataata
     4861 ggaatttttc gtttctaaat attccaattt gggaatccaa taaaaatttt cgttcaaata
     4921 cgtgtctatt cgaactcttt tctagttgtt aattatgaag ggggaagaaa taaaaaatac
     4981 aatctataca cgaataagaa tattatccaa aaggaggttt tagaaaagat ttattatacg
     5041 taaaaagctc aagacatttt cttagccata aggacatgtt tgatatttaa gaagatatat
     5101 gaattttctt ttctaagtat aaagataact atccattatc aactaaaaaa acatttttga
     5161 aaataaacat cagcagtcct atcaatgcat gtgagcttat agaagttatt cgcagcgcag
     5221 cataattgca ttagcttctt ttcgtgtttt ttgcctcttt tccctttaaa tcttaatgga
     5281 ggaggtgtgc aatatgtcag ataacgacga acgcgtaaat gcccagttga ttcgattctt
     5341 tgaaaaggtc attttgaaca ccgctaatac ttattataaa aaacaagaag aaattcaaaa
     5401 acatgaacaa cttgatcaac tcccaccata tttgtttact aaagatacta taaaatttaa
     5461 acaaccgatt aatgttttaa atgtgactct ccttgttgaa gatataaaat tagcaaaaat
     5521 ccttcctttg ttgaaagaac ctgaacaaat ttttcttatc gaaaaattta tctttgataa
     5581 aactgataaa gaaattggaa aggttctggg gattacaaga cagggtgcga caaatttaaa
     5641 acatcgactt tacaaaaaaa ttcaaaaaat gctggtttaa tatctgcata ataactaatt
     5701 ttgtatgctt ctttgctcgt tctcctcctt cccaaagaaa tagattataa gtccatggga
     5761 agaaggtaga tttatgaatt ctttaaaaga agatttcatt ttagcaaagg ctggaaatga
     5821 agaagctgtt gaggcaattc tcaaaagatt tagctctttg attcataagc aatcctggag
     5881 aactggaaaa tatgatcaag attgttatca agaatgtatg cttgcaatat atctagctat
     5941 ctcgaaattc gaaattaaag aataactcaa ctaagggagt ctgtgacata agtaaaaaga
     6001 tagtttcaaa tttcgaacaa taaatttgaa actatcttct ttataattat aaagtatcga
     6061 ttttacagcg ttctataatg attcatagaa tctaaaacga atgattttaa ttatcaacgt
     6121 tttttaattc gtttttagct taaaaataac ttttgtcaca gtctcactcc taaaattact
     6181 ttatttacgt atgaagtggg caggaggtcg aatccagaac tgggctatgg tacttcaacg
     6241 aggacttctc ctctagaatt gaaaagcatg cgatttacct tccgtaacga cggtagattt
     6301 attcaactat gtgtccaatc aaaatttgtc tgatttcaaa aatagtcaag agaattttgg
     6361 ttgttaaaaa ctcttatcta tcaacttcca cagtttagtt gacaaaccct gatactaagt
     6421 tgggctatga tacacttttc ttgactatca gttacgttac cggaaggaat gaactctatt
     6481 gagaaaaaca tatgatcgta aatttaaact aaagatttca caggatatcc ttgagaaaaa
     6541 agtaactacc aagaaaattg ctgaagaata caatatctct cgtccaacaa tttcccgatg
     6601 ggtttcagaa tatcgtcgat acgggaaaaa tgcttttgct ggacaaggaa aaagattacc
     6661 tgataaagca gatttctaca ttcttgaaca ggaaaataaa cgactaaaag aggaagacga
     6721 gtgttctacg aacacaaaga tcgatacgga tctccaggga tcactcaaaa actttacgat
     6781 gaaggaatcg aaatcaataa acgtgttgta gctgttctta tgcgtgaaat gaatttatgc
     6841 acaagaggat ttcatcgacg caaatcttct catggtagag aaaaaacaat caaagaaatg
     6901 gtaaaaaaat gttgaatcga taatttgaac agaaccaaat tgatgctgtt tgggtgatgg
     6961 atattactta cattccatgt aatgacggtc gcctctattt gtccacctat attgacttag
     7021 caactcgtat tctacgttac tatatggtag attcacacat gaaaaaagag attgtcgtcc
     7081 gtccattaca aatttattaa ggagaattgc ctacggtaat tcattccgat agaggtagcc
     7141 agcatcggtc ttttatttat caagagctgt tgaacgacca ccacatcaca cattcagtga
     7201 gccaaactgg gactcctgtt gacaatgcag taattgaagc gtttcatcga tcaatcaaat
     7261 gagaattaat cgactccaac aaatataaaa gtaaaataga gatgaaggtg ttaatccaag
     7321 attatttaga agactactac ccaaacaaaa gaatccatac aaaatttatg atgactcctt
     7381 gacaatttga agcgaagaaa ataagggatc tataatatct agtgttggtg acgccttctg
     7441 ttgccaatac tttttctttt ttctaataaa cgcaaacaga caccttaaaa tcctttagaa
     7501 taaagtcgac gaaaaccatt caaaggagtg tttcaagatg tcctattcag agtttaccaa
     7561 agagttacta gatattctag acctaaatct tatctttcat gaagatgcct ttcgcaaaga
     7621 gcgaatcaat gacgaaacat gttttgtttt tgatggcaca ttgacctatc aaccggagga
     7681 atgctttcat cgccactatc aaaatgaaca aacgatcatt aaatagggct ggaaaaaagt
     7741 atccatctta ttgaatgatg tcagtaacta caagaccatt ctgcggatta acaaacagcg
     7801 cttcaaatgt aaacactgtg gaaagacttt tttagcagaa gattcagtta gtgatcgtcg
     7861 ctgctccatt gctcgcagag tcaaacaagc cattcttgag ctattaagcg aacctctttc
     7921 tatgtctttg atcgcacgta tgaagcacat ttctccgacc actgtcattc gaatacttcg
     7981 cagccttcgg cctaaaacca tttctttgag ccagctgtta ccagaagtgg tgtgtttcga
     8041 tgaattcaaa tcagtgaaaa atgtctcggg agccatgagc tttgtcatga tggacggcaa
     8101 gacccatcaa ctgattgata ttgtggaaaa tcggcaactc aatcctttac gcgactattt
     8161 cttgcgctac cctataaaag tccgtgaaca agtgcgtcta gtggtttcag atttctatac
     8221 accctatcgc acattggtga aagagtgttt tccgaatgcc cgaatcgtcg ccgatcgctt
     8281 tcatattagc caacacattg gtcgggcttt taccaaccac cgaattcaag taatgaagac
     8341 ctttaaaaaa ggggatcgtc ggtcgaagca cttaaagaaa tactggaaac tacttcaaaa
     8401 gaatgcgtgg gaattgaaag gtcagcatcg ctactggcgt ccgtcatttc gagatcatct
     8461 gacagaagca gagatagtcg atcggctatt atcttatgat gattccttaa agcgaggcta
     8521 cgaagtctac caggattttc tttccgttat cagaagacaa gatgttcctg aattcgtcgc
     8581 gctcctaaaa gaagactaca aggagttgcc agagcactac caaccagtgt tcacgacctt
     8641 caagaaatac caaacagaaa tcaaacgagc gttgcgcgtt ccctattcca acggccctat
     8701 agaatgtttg aataaccata tcaaagtact aaaacgaatt gcctatggct atagaaactt
     8761 tcaaaactac cgagaacgaa tctttttata tcgaggaaaa tattttaaga aaactaagaa
     8821 tactacccaa ctgactaaag ccagaacaac aacacggcta gacaagatag ctgtctagcc
     8881 gtgtgagtat ctcgattatt ctattgaatt tcttcaccaa cactcattga cgaagagcca
     8941 aaataagtaa tctaaccgac tgttaactaa accattgcag gtcccgttaa agatacttgt
     9001 gcctgttgtc accgcttctt tttcttgtcc acaagcgctt aacacactta ataaagcccc
     9061 tgctattatt aataataata tctttttctt attaaaaacc tcctcatcta tttccagatt
     9121 agtaaatgta gtaatctgtg ctttcttttt tctcaatact aataactaac ttatggggta
     9181 aacaaatact cgtttgaccg ggttttgaga tccatccagt tctaaccgcg atttgatcag
     9241 gactattatc ttctttaact cgaattcttc catctttaat ctcaacaata ttatattgtc
     9301 ccttcgcagg atgataattc acgagtttat gattgatctt atccaaatcg aagcgatcca
     9361 tttccttgcc atcaattcga acgatggcat atttgatagc atcttcagtt gtttcattct
     9421 ccttttctat agagaataca aataagggaa taaaagaggt aataatcaaa atgccaataa
     9481 ttatgacatc gcctatcttg acaccagctt ttcttaaaaa tttcattaac gatatctggc
     9541 taaacatatt agactttttc catggaaatg gtgaaatttt tcggaaatta tctgcattaa
     9601 gagaatcagt taaacaaccc tcaagttgtt ccttaataca ttgttgatcc atcttcatac
     9661 caataaaaac tagtttatta atgcgttcac caaacaacgg atgccaggct tccttcaatt
     9721 cgggattttt ttgtataatc atttgacact caattttagg taaactagct acccaataat
     9781 ttaatgattc aatactttta tagctacccg atgtttcaaa gatcgtcgaa aaatcactat
     9841 gttgggcaaa ccaaagaaac ccttttgctc ttgtaatatt gccaggaaaa tttttatccg
     9901 taagatgggc aaatttttgt gcgtcaagga gtaaccgatt tcgatagata aaacttgaga
     9961 taccatattc ttctgtttca ggaatatgat tttgatagcc aagctctaac tctttgaacc
    10021 agcccactga ataggaagtc tcatctatat taaaaagatt tgtatttaga attttcgata
    10081 agtctacttc acctttaatt gtcctaatta ttttggcatt ggactgtaac ttagcaatta
    10141 gaccgttaat tttgtaaatc gtcttggttg acactaagtc actattattt aaaagtaata
    10201 tgttacaaca ctcgaattga tcaattaaca agccacgaat atcctgttct tcttcaacta
    10261 cattaccttc agcttttctt tcctgaatct tttcacccgt ttcgaaatta tcccaaaaac
    10321 gttttacatc cactactata ataatggcac caatctctaa tcgttgggtc aaatcaatgt
    10381 ctaaagggtt tttagctaat ataattgctt gaataattgg aattggtttg ctgattcctg
    10441 aagcttcaat aacaatttga ttcaagtcag aaaattgcac taattgatct agttcaacaa
    10501 tcaaatcttc gcgtaatgta caacaaatgc atccattcgg catcgaaaca agtttttctc
    10561 cagttctttt aaaacctttc ttgtcgacta ataccccatc aacatttact tcccctatgt
    10621 catttacaat gacagcaatt ttctttccgt gatcaccgta cagaatatga tttagaagta
    10681 tcgtttttcc tgaaccaaga tagccagtta agattgtaat aggtattttt ttcataggga
    10741 acctctttct ataccttgaa tttacacttt aagtgcaaca cataaaaatg agtcataatc
    10801 gatatccaac tagtataagt ttgtcgagaa cactcctaga aggaaaataa ttatgagcca
    10861 gtatcgtcat cttactatac tcgaacgaga aagaatcttt ctgcttcacg aagaaggatt
    10921 ttctattagt ataattggca acgacattca gcatagcccg tttactattt tacatgaact
    10981 gagaagaaac aagaaaaaaa ctattcacct tccaaagcgg aaaaaaatta tgcttatcga
    11041 agaaaaaaat gcggacgtta tcacattcta aatgatccgt gagtttggtc aattgttcgt
    11101 catttatttg tcgattttca gtggtcgcca gaggaaatct cgaatcgttt gaagcatgaa
    11161 catatggact tttcaattag ttttatcacg atctaacgtg caatttgcaa tgatcttttc
    11221 gatacagaac ccctctcaca cggcaataaa ggcctgatcc gttcattgca ccatcgagga
    11281 aaaacaagac atacaaaaaa tcatgtcgag tctcgtggaa agatttgcct tactcattcg
    11341 atccatggcc gtccaaaatc cgcagatgat agaagtgatt ttggtcattg gaaagccgat
    11401 attgtagctg gcaaaactgg tggtacttgt ttagtgactt tgacagacag aaaatcatgc
    11461 ttccttttag caggaaagaa ggtccccaga aagaaagccg cttatgtgag cgagaaaatg
    11521 attgaacttt taagcagtat tccaaatgag gcggtcaaaa cgatcactcc agatagagga
    11581 aaagaattct ccaatcattt cgcagttaca gaagcattga ataatatgcc cttttatttt
    11641 ccagatcctc atgcccttgg caacaatgaa caaattaaaa tacgaataga ctcattcgag
    11701 aatacttgcc aaaatcgaaa gagatagcta cggtagataa ctcaacgata aatcagatga
    11761 ttgaaaaact gaataacaga cctagaaagt gtttagattg gagaacacct tatgaagtct
    11821 tctttgataa agtgttgcgc ttgatttgac aattcaagac ataataaaaa gcagatcaaa
    11881 tccaaataag ggaaaaatga tctactctgg tattatcaat taattggcca agctattatg
    11941 ccgttttgct aaacgtctac ttcttccagt attgaccttg ataaaacaac aatcaggatc
    12001 ccgttttaat actctatgaa ctgtgtcaat actaacatgt aaagttgcag caatatcagc
    12061 taatgtactc ccatttaatc tcatttgctt tgcaaatcga taacgccgat aagcatcaat
    12121 attcttggaa tccatagaca ataatacttt tcttaccatg tatttcctcc aaaaattgaa
    12181 ttttaatgag ccatcatttc ttgagcaatt tcatgtttag acaatgaagc tggatagaaa
    12241 gtaggccaat tatgcaattc attatagagt ttttcttgac tttctccacc aaagaaaata
    12301 tggaaatgct ctgccttact tggtgcaatt ccatgatcac taaattgaat atatttaaaa
    12361 cgaccagcac ctgcatcatc agtttcaaaa ttaaaacgaa caccacggtt tcctttttca
    12421 taattcaaaa ttttgtatcc aacatatttg tatgtgtatt gatgatgttc accgttgact
    12481 acaaaatcaa tggtgttgtc tttaatgttg atagtatcaa tatctgtctt atagccagta
    12541 gtataataat ctttgtactc ggcagctgtc atgtctttat tgatttttgc tttgtaatcg
    12601 aaaacttcat ccaaaattcc atcttttaac aacggataaa cagattgcca ttcgcctgta
    12661 taatcactca attcgcgatc cttcacatcg gcatctttaa agtacccatt agcaactgtc
    12721 ttttcatcct tcgcttcttt ttctggaact acctcttcac cagcaaccat agttgttttt
    12781 tctaacgctt ttagattgtc ttccattact gaaacataat cttcaccatt atccatttgt
    12841 tcttttgtaa gactttcaag aggattcagt acttccaatt ttatcccagc ttcgttggcc
    12901 aaagtttttg caattttatc attagcattc ttttcaaagt aaatataatt gatcttattt
    12961 tttttaacat actcttttaa ttcagctaat cgaccagaag atggctcttc ttcaggactt
    13021 agtccagcaa taggaacttg tttcaatcca taatccaaag ctaaatatcc aaaggctgcg
    13081 tgttgcgtca caaaactttt ttgtttcgct tctttaagac tagtggtata gtcagcatcc
    13141 aaccgtttca gtttagtcaa atacttttca gcatttgtct caaatacttt tgcttttttc
    13201 ggatacaatt taactaactg atccttgata tttgaaactt ccttaattgc cattttgggt
    13261 gaaacccacg tatgaggatc tagttcatga tggtgatctt cttctccgtg atcatgatct
    13321 tcttcttcac tacctggcaa taaaatcatg tcttttgttc cttctactac attaggccca
    13381 gctttcttcc aactttcttt agcttttggt acccatgatt ccatgttttc gttatgatat
    13441 acaaaaacat cagcatcatg agcttttgcc atatccttag ctgagggctc atagtcatga
    13501 ggttctgatc ccgctggaac cattaaatcc acgttcgctt catcgccgac gatgtttttg
    13561 gtgaaatcat acattggata gaatgttgtt acaatttcta attttccatc tttatcattc
    13621 gatacttttg catcattagt gctggagcaa gctcccaata atcctagagc tgctatccca
    13681 ataagtccta cactgatttt cttcattctt tttccttcct taattatgct aatttcttca
    13741 ttttatttcg tttatgttct ttgataattt ttaatgccct ttttctagtt ttaatattcg
    13801 ggcttttaag tcgtcgatat gcactagata tatccgtttt ctccattaga aattaccccc
    13861 aatcactact tatcattatt tgctttccgc cagtaattta tcaaaactct gtttgatcct
    13921 ttcttcatcc aacatttttc cgattagaat aatagtggtt tggtcttttt gtcgagtggt
    13981 gtattgaaaa ttaacctgtt cgtttacctc ttgcatggca actataaaat cctgctcttg
    14041 taaagcaatc aatcctttaa aacgatacag gctcccttgg ttggttaaaa tcagccagtc
    14101 aatccattgg agtaaaaaat ctttttttat gtcttgatct gaagttaaga gaattgattt
    14161 aaactcatgt acttgatggt gttgatgata gtatttgcca ttatagtgat tttctgatga
    14221 atcactttca aaaactaagg gatgattaaa ttttttcaaa ttataaaaat cctttttttg
    14281 aatcgtttca ctatgtgtga acattcgaat atcggataaa gggttaatac ttttgatttc
    14341 tctctgtaat ttttttagtg cagataaatt caagttttgt tttctagaca caaaaatgcg
    14401 atctgccatg acaagttgct taagggcttg tggttctctt tcaataagtt caaaactgtc
    14461 actatcaata acagtcaata aactatcgat atatactctt cctcttagtt gaggcgctgt
    14521 taaaagtgtt tgaatgattg gttggggatc tgctatacct gtagtttcaa tgatgatttg
    14581 tgaaattggt tgttgatgtt cttctattgt ttccagtaaa gaaatcaata ttgctaataa
    14641 atcactgcga agactgcaac acatacatcc attatttagt tgtaacaccc gttcctcgct
    14701 atgaactaat aatttgtgat caatcccaac ttcaccaaac tcattttcaa ttataataat
    14761 ttcttccctg gggtagggtg agacttgcaa ggcttgattg attagcgttg tttttccagc
    14821 ccctaaaaac ccagaaacga ttgtaactgg tatgcccatt ttgtcacctt tttaccactt
    14881 agctatttca cttctttaaa aattgcccgt ctgcgcaatt ttggcgaata cttttttaat
    14941 tctaaccgtt cagggttatt ccgtttattt ttgctggtga gatacagacg ttctccagtt
    15001 tcgacacatt ccaaaataat attttgacgc ataaatcttc ctccttcaat acttatcgat
    15061 cttcaagata tgcttgaatt tgttgtgcat cttcaaaagt taactcgcca gattccaatt
    15121 gtgaaactaa attttctttc atatcaacag gtatctccca ataaccatcg atacattgaa
    15181 ataactcctc gtcatactct tcaaaaattg gatagattct taaaaaatca tcaaatgata
    15241 agccttggtc ctcatagtaa tctttgacta atccattttc aattgcctgt tgggtcggta
    15301 aacccgtttc agtaataatt cctctctcta ccatcgaacg ataaaaagtg catttatcta
    15361 gcgattgctg ggtcgtttca agataatact ttaatccttc ttcaactaaa ggtgggtaaa
    15421 taatttccat tttgattccc tcctaaaagt tatatattaa actattttga agctccttta
    15481 attactttct ttccattata gtaccctttt aaagatacat gatggctacg tctataatca
    15541 ccattcgctt cgtcaaatga aatttctggt tttactacag tttgatgagt tcttcttaac
    15601 cgtttcttcg ccttagatgt ttttcttgct ggtactgcca tgatatttcc tccttttacc
    15661 aacttgcttt ttttactcca ggaatcaacc cttgatgggc aagttctcta aacttaatac
    15721 gggacatacc gaactttcgc atataccctc ttggacgacc atccgtctga tcacgaagcc
    15781 tcagacgatt cggatttgaa tctcttggca atttagcgag agcggtgcga tctcctgcgg
    15841 cttttaattc ctgacgttta tctgcatact tttcaatcat cgccatttgt ttctttgctt
    15901 tagcaatttt cgactttttt gccatatacc tttatactcc ttttattttg atttagacac
    15961 ctcaaatcgt aatcgttacg ttttgacact gatactttac caacaagagt tgctcttgtc
    16021 aacaataaat aacatgaaat aaaactcata tgaatagata actatttgaa aacgaattta
    16081 tcggtacata gagataatca aatcatttaa aagaatatgc agtttaggct ctgaaaaata
    16141 agaattcact tttattagtc caatcaaaca caaataccgt tttaagtagc ttttcctcta
    16201 cttaaaacgg caatatgaaa gaaactataa ctttttattc aatcttttat gtttaactgg
    16261 tttatcgcca attttttaaa actttgatta ttccttatat tataagaata gacattaagt
    16321 gaactaattc aatcatactg attctttcgt gtattcaaaa ttagatgctg tttaataaaa
    16381 ttattctttt tgaaaaagaa ttataactat atcccaaaaa ttgtaggtta atttaaagcc
    16441 tatttcatca tcgtgattga gcttcttttt catagacgaa tttctcagat agtttagttt
    16501 tctttatgag atttttgtat atttctgacc ttcgatacaa ctcattatga gtaccttgat
    16561 caactagttt tccttgatcc atcactacaa ttttatttac cttttcaata gacttcaagc
    16621 gatgcgatat aattagtact gtcttatctt gtattaaacg atttaaactt tcctgaatac
    16681 gtttttcatt ttccgcatct aaactggcag taatttcatc taaaattaaa attggcgcat
    16741 ttttcaaaaa agcccgtgct atggataggc gttgtcgctc tcctccagaa agtgaacttc
    16801 cgttttctcc gaccaatgta tgataaccgt caggtagttt ttcaataaag tcttcgcagt
    16861 tagctaaacg agctgctttt ttcacttcct catctgacgc ttgactattt ccaatacgta
    16921 tattttccaa aatacttgta ttaaacaaag ttacctcttg aaaaacaata gcgattttgc
    16981 taaacaaaga agctggagat acacgtttaa tatcataccc atcaattaaa atacagcctt
    17041 catcataatc atacagtcta gacactaatt tcaagatact agttttcccg gaaccactag
    17101 cacctactaa cgcagtcact tctccttgtt tagccgtaaa agagatatga tctaaaattg
    17161 gggtattgtt atcatatgag aaagagacat ctcgcaactc aatgtcaaaa gatttcagag
    17221 gactatctga tccctcttgg atactggttt ccttcatagc tctaattcgc tgtattttag
    17281 gagctaaata aaatatttca agcactgctt ctttcataga atcgaaggaa tcctttattt
    17341 ttattgcggc tagtaagtaa ccaacgacgt agagtatagt cacttcaccc gttaacagta
    17401 agtgaacacc tactagaatg actactgcta aactaacata tgagaaaata gaggataagg
    17461 ccatgactga aaaagtactt aattctacct ttaaatgaat cctttcactc tcttccattt
    17521 ttttgaaaag tctgtcttga acttttttag atagattaaa gctattaatc tcttgctgca
    17581 attctatagt ttcttgaaat tcttccgagt tctctctcaa agtatcgtaa tatttagtat
    17641 tggctttcgt ttgggatttc tttgataaca agattaagac aaaactaaat aacgttggca
    17701 aaataacagc taatcccatt ttgacattac caaccaaaag catcactgaa ataaaaggga
    17761 aaaacagagc cataccgccg gctttaggta ttgcatgact catcgcatgc tcaatacctt
    17821 caacgtcaga catgatagtt tgagataaat ctgataaatt atgttttgaa aaataggata
    17881 atggtaaatt tgacaaatcg tctgcaattt gcactcttaa atgcgcactt tctttataag
    17941 tactattata taagttttca tactccctat ctaacaacca atacatgaaa agcaaagtaa
    18001 caaacgatac ggcaaaataa agccaacggg gctttgtatt ttctaaaact aattcgtcta
    18061 tcagcatcat tataatgaat gctggtacca tattaatgca gtatacaaaa aaactagaaa
    18121 tagaagcttt agttaaagct tctgcgccct gatcacttaa agcaaatttg tttttataaa
    18181 aacttttcat tgtcaagcct ccaatcattt gcattctcat aattagtgac caattgttta
    18241 tacacttgat gtttagccat taattcatta tgatttccac gttctactat tttcccttct
    18301 gacaagacaa gaatttcatc tacagattta atgctggata atcgatgagc tatcataata
    18361 actgtttttt ctttcatcag atgttgaaaa gccttttgta gttcatactc attatctgga
    18421 tcaatagatg cactggcttc atccataata acaatctttg catcttttaa aattgctctg
    18481 gcaatagcta tacgttgttt ttctcctcct gacagataaa ctcctttact accaattaag
    18541 gtatgctctc tttcgggaaa tttttctaaa atcgattcgc aaccggctaa tcttagcgcg
    18601 tcaaatactt tacttgctgg cgcttgagga tttgctatag aaacgttatc gtaaatactc
    18661 tgattgaata gtttcgtatc ttgaaagaca aaagcaattg tgttaataat tgtgtctttt
    18721 gaatagtgat ttaaaggctt accaccaatt ttaatctgtc ccttatccac attgtagaaa
    18781 cctgaaatta gtttagctat cgtactcttt ccgcttcctg attttcctac taatgcataa
    18841 attctttttt gttctaaaac taagttgaaa ttttctaaaa cacactcttc tttgtatgaa
    18901 aagctgacat tttcaaatgc aatgtcacaa tttttaatct gtgtctcgtt cccatatttt
    18961 agttggtctt gcttcatttc taaataaagg gagtctagtg tttcgactgc atatcttgct
    19021 tcaaacaagt gcatacttac atacattatt ctcatgaaag aaacaaaaat aattccactt
    19081 aaaaaaaaca acatcaacaa gtcaacagct aatatcttgg gagtggtaag agaagttata
    19141 aaaaaggtta taggaactat caaaatgcaa actatgccaa aaaatagcca ttgaaaaaga
    19201 acaaaaggtg ttttcccact caaagaatac ttatatgcaa acttagcata atcgttaatt
    19261 gctttattca aggctttaaa tgatgttact ttagcaccaa atatctttat aacttgaatt
    19321 ccgcggatat attctaccgt ttcagagctt aacacatcta acgattcttg atatttttga
    19381 ataaaatttg tattctctgt cattttcttt aacaagaata caccaattac taacatggcg
    19441 attagaacca atccaatttt aaagttaatg aaaaagccta aggcaactga taaaacaggt
    19501 gttactatgg cttgagcact atctggaatc aagtgagcaa ttgccatatg tgttttagcc
    19561 gcgttgtcat caattgtctt tcgaatatat cccgaagaat ttaaatcaaa aaaacgaaaa
    19621 cttgcttctg ttaaaccgct aattcccttt tttctcaaat tagtctctaa gcgaaaccca
    19681 aggatatgag aaaataagcc agaaaaaata taaaataaag ctcctaaagt taaccaagca
    19741 acagtttgaa ccgcataact cttagctaaa tattcatctc ctacaataat tagagactga
    19801 agaaatttgt aaatactgta atatccatag actgttaata cgacagaaaa atcagaaaat
    19861 aaagtggcta accatccgta gtatttcatt ttagggacat aactaaataa ttttttgtat
    19921 actttcattt tttcctcccc cgcattcaat ttcttctctt attcgtttac aactgttaat
    19981 gctttccgta atagcgtaaa ttagagatgt acaaacagat aaaaggtaaa ctacgttcta
    20041 ttttttgtat ttttttaaga cttttcttcc aatcaataca ccaatcatag ataaacttgc
    20101 tacaactaac actgaaatga ttccccatat acctaccgca tagtggatca ttgcatccat
    20161 tgttgcagca gattgtcctt tatctatcca atcttgacga aaacgatctg taaagaacca
    20221 tataggaatc cactgtccgg cagcactgcc taattgcatt agagcccaag acgcaacttg
    20281 aggaattgct cgatcatatc caaatacaga tagaataata tcagctaaga tcgccatact
    20341 aatcgaactg ataaaccaag gtaagtacgc cccgcccatt aacgtaaaaa ataacaataa
    20401 aacaattgtg taaatagtaa aaattccttt tctagggtag ttatagctaa tataaacaaa
    20461 tatgattcca gataataatc caaaaatccc gggggatatg ctgtgaccaa acgccccacc
    20521 aatactacta accattattg aaaaaaagta aattactagg gaaataactg tagctaaacc
    20581 aataaaaata taatcttttg ttttcatata tattctcctc aattctattt cgttatgtca
    20641 ttaaaaatct gttctatcaa agttgaatct tctactctaa gttttatatc tttttttatt
    20701 ccaccatttt ttaaataaat aattctattg catgttttat aaagaaattc cggatcatga
    20761 gtagctataa ctactgcacc cttttctttt aagtctttaa taaggtcagc aatcctttcc
    20821 atattaatat aatccaaccc acttgtaggt tcatcaaata gaaataaatt agtttttgac
    20881 aatgaagcta tagaaaccaa taatctttgt ttttctccac cggataaatc aaacggtaat
    20941 tgatctttca ttttataaag ttccattttt tttaaaattt tttcttgctg atctttacta
    21001 actatttcat tccccagggc taactcgctc ctcactgatt ctgtgaaaaa ttggtaatcc
    21061 atttcttgca ttactaaaaa cggcgatgac aaattttttt tattttcgat tatctttcct
    21121 ttggtagggc gaataatctt catgagtatt cttagtaagg ttgttttccc cacaccgttt
    21181 ttccctacca aaccaataac atctccaact ttgacatcaa aatttatgtc ttttagaata
    21241 ttttcataag taatttcttc aacttttaat acatctgcac ttaccttttc gatataggga
    21301 acttcaatcg aactattaaa aatgtcaaat ttccttaatg cgttattgtt ttcagttttt
    21361 aacaactgaa tagttgtagt ttttacagtt ctatttttaa caaatagaac ttgatcaatt
    21421 aattctttca aatagtaaaa acgatgttca gctataacaa tagtaaatcc tttatttttt
    21481 aaatcacaaa gtaagtcagc aagtttctta gtcgctttga agtccaaatt tgaagacggt
    21541 tcatccaata taattaattt agagtttagc gataaactac atccaataga aattttctgc
    21601 cgttcaccac ttgatagcga aaaaatgttt ttatctaata tatttgaaag atctaataat
    21661 tcagctaatt cattgattct tttatccata tgctcttttg taaatccaaa gttttccatc
    21721 gaaaatacta actcactcgt tgtatttgtt gtaaagaatt gtcctctagg atcttgactt
    21781 acgtagccaa tattttttga tatactttct tgtgttaagg attgtagcga gttattttca
    21841 aataaaattt ccccaaccaa ttttccgtca taaagtcttg gaataagtcc attcattaac
    21901 tttaatagtg tggatttccc actcccagaa gaaccagtaa tcaatgtaag actgcctttt
    21961 tttattgaaa aattaaggtc aacaagcgct tgttccttaa catccttata tgaaaaagaa
    22021 acattgttaa attcaaacaa ttctttcacc tcaaatcaaa atacttaaga aaaaaatagt
    22081 aacggaaaac aggatgatat agtctaataa gctcatgttt gttttatagt aagaacttct
    22141 tttcacagga gattctatcc cctttgttat tgcattagcg gtcatttctt cagcaatcat
    22201 agttgcacgt ataagaacgg gaactaacag aaattccaaa tattgcagag gctgaaaaaa
    22261 agacaagcga atgtttctca tttttaaaga ttctttaatc attcttattt cagaacgata
    22321 agtcggaaag aatctgatca ctactgtaat acttaacatt atttttttcg gtaaatgtat
    22381 tttttctaaa gaggataata attcattgct agtatagaca ctaaccaaca accatgagat
    22441 cattacgacc ggcaacattc gaaatacaat atataaggat gtcgcaaaaa atatagtaaa
    22501 aaactctatc ttgatagcat caataatttt cattactaaa aacagaactg aataaatcaa
    22561 gatgaaataa atacatgtct ttattttacg aaacatcaat actaaaactg tagcaataat
    22621 gaaacacccc acttgaaata tatttccctt tcctaaaaaa ataatgaccg gaaaaaaaat
    22681 atttaaagta atcaaggtta acggattgat ttttgacact ctttcacctc caaaaaataa
    22741 gatcgcactg ttatcttaag ctgataaaaa tgcaccgtta ttcagataac agtgcgatct
    22801 tatcaaaaag cataactgag aacaattctc aatgcaagct ttttttaatt aactcagtaa
    22861 ttcaatccac ccaggaacag aaaattgata caatcttctg gttaatagca tagtcttttc
    22921 ttttgaatag ctatgcttca atatatcata gaatgtagcg tagaatgagt aaatgtagaa
    22981 gtggatttct tcttcattaa agactaaatt ttgattgatc attccgatag tctttaactt
    23041 atctagacaa cagactgtct ttttcgtcac aaatgatgta attttttcaa caatatcttg
    23101 atatttggtt ccagctgatt ggaataaaat caaatcgaat atacgtttat tctcaaaaat
    23161 ataattaata aatggatcta attcattgaa gttctctctc caacttttct ctatatctat
    23221 attttctaag tttaagaggt atttggtaaa ctcttcatta tacatattaa taagcgcatt
    23281 aatatgcggc tgaataattt cttcaaataa cgcttcctta gaagtaaaat gtttataaaa
    23341 agcacccgta gttacgcctg cggtcaggca cagttgcctt atcttagttt gctgaaatcc
    23401 ttctttttca aaatggctta gtccactttc tattaacttt tggtgagtta taatataatc
    23461 tctggtttct atgggtactt cctcctaata agatgaatta actttattat cttacacagg
    23521 acttgaagtt tcaatcgtta acgtttatta ctgaactcat tccttagagc taaactaatg
    23581 agaaagagca gaataactga tacaaaaagc aatcctacaa gaattaatag actcatctaa
    23641 atcattcacc ttttctaaaa taatccgaga aagatttaaa aaaattatat ccagctatta
    23701 ggataagtcc tatcataatc actccaatag ccattttctt atcctcccta aaaataaagt
    23761 cttttactta aaaccttttt tgtaatcgtc aataaatttt ttccctttat cagttaattg
    23821 aaatcctata tctaaatagt cctcatatct aagtttagcc agcatctcac ttacagatgc
    23881 tggactaaca cttagaactt ttgctaaatc attatttttt aatttctttt ttctttttga
    23941 taattcctga attgctagta aataaattag tatagtagtc gttttaattt gtaccatacc
    24001 taccctccaa attatttcga aaggccttca gcaattttat ccaggttcca tttcatcatc
    24061 gcatagtaac tatcaccatc ttgtcctttt tctgcaattg aatcagtaaa aatcgttgaa
    24121 tagataggaa tattggtatc ttttgatact gttttcattg gtctatcatc cacactgctt
    24181 tctacgaata aggagggaac ttttgttgtg cgtaattttt caactaagtg ttttatttga
    24241 tctggtgttc cttcttcttc agtgttgatt tcccaaatgt aagcagaagg cacattatac
    24301 gctttcgaga aatatttaaa gcatccttca cttgtaacaa tcattttttt atcattcgga
    24361 attgaagcaa atttagattt agcttctttg tctagagaat ccaatttttc aatatactta
    24421 tctagatttt ctttatagaa ttttttatta tcaggatctt tttccgctaa ctgtttttca
    24481 atatttttag cgtaaataat accgttttct aaatttaacc aagcatgagg atcttccttc
    24541 cctttctcac tctgaccctc taagtaaata acatctatgc catcacttgc tgcaaaatag
    24601 tctttgtttt cctctttgtt cgcattttta actaattttg taaaccaagc atttcctcca
    24661 gtttccaagt taacaccgtt ataaaaaatc aaatctgctt ttgaagtttt ttgaacatct
    24721 tcaggcaaag gttcatattc gtggggatct ttcccaatag gtacgatact gtgtaaatca
    24781 attttatctt ttgctatatt ttcggtaata tctgctaaaa tcgaattagt aactactact
    24841 tttaattttt cgttcgaagc cactttatct ttgtctttac tatttattga acatgccccg
    24901 aatataaaaa gagcaatcaa aatccccaga cttcccagta ctgctttcca ttttctcatc
    24961 ataacgatct ctccttcttt cttaaaaatt tttgttttgg tgagattaga aaactaatta
    25021 caaataagaa tgccgctgtt aaaacaatac ttgatcctgc tgctatgtta aaactataac
    25081 caataaacaa tccaagcaat gatgaacttg ctccgactgt tgcagaaata aatatcatag
    25141 ttttcaagct atttgcatat aaatatgctg tagctgctgg tgtaattaac attgcaacaa
    25201 ttaatatagt tcccacactt tgcatagctg ttactgctac taaagttaat agaaccatca
    25261 atagataatg ataaaaactg acattcatcc ctattgcttt tgccattaat ggatcaaaag
    25321 aagtgattaa taattcttta aaaaatagaa ctactataac caacactaaa accgaaacgc
    25381 caattgtaat ccacttatca atatcttgta cagctaaaat atttccaaat aaaatatgaa
    25441 ataaatccgt tgagctattt gcaactccta taaggataac tcctagtgct aaaaaagaac
    25501 tgaaagtaat accaattgct gtatctcctt ttattacact attgcttttt ataaaagtaa
    25561 taatgataga agctaataga ccaaatacaa tcgcaccaat aaaaaaatta atacctaaaa
    25621 tataagaaat tgctactcct ggcaaaacag catgagaaat agcatcaccc ataagagaca
    25681 ttcctcttaa aataataaaa caacctactg ttccagaaac aatccctata actacagatg
    25741 taattagagc attctgtaaa aagtgaaagt catacagacc attaataaaa ttttgaagca
    25801 tattattccc cctctccaat aaatatagta tctccatagg ctttttttaa attttcttca
    25861 ttaaatacag attctacact tccgtgagca attagatttc gattcaaaag aataatatta
    25921 tcaaaatact tctttacctt gcttaaatca tgatgcacaa ttagcactgt ttttccctga
    25981 tgtttcaatt tttttaacgt atccataatt attcgttcac taactaagtc tatccctaca
    26041 aatggttcat ctaaaaatat gaaatccgca ttttgagcaa gacatcttgc taaaagtaca
    26101 cgttgaaatt gtcctccaga taattctcct atttgatgat tagaatattt tcccatatcg
    26161 accttttcca aagcctttga aactctttgc cattctgcat ttttaattct ttgaaaaact
    26221 ttcattccgg catatgttcc catagataca cattctttta cttttattgg aaaagtaaaa
    26281 tcaatatcag ctttttgctc tacatatgca atcttcacca gttttttatt gatatcttca
    26341 ttattaatgg agacctctcc ctgatgaggg ataatattta acattgcttt aagcaatgtg
    26401 gattttccag caccatttgg accaataata cctgttaaag caccttcttg tatttttaaa
    26461 gaaatctcgt tcaatgctaa aaaatcgtta taacaaacat taagcttttt cacttctaac
    26521 ataactttct ccttctaaat gataatgatt atcacgatca tatggtatac aaaaattata
    26581 ttttagtcaa ccctaaattt tatagtttag atttttttct gttgctgaag attagaatga
    26641 caaaactatt tgaaactacg cgtatagtaa gtagctttca aaatatataa aaaaggagcg
    26701 ttctcaaatg agaacatgct cctaaaacta ctttattggc gtatggaaaa attatacttg
    26761 aagtggatag cgggttgaat aagttgataa gcatcaaaac atttataaaa attattcaag
    26821 actatgtctg ttccatatac aaatatgaaa atcagtaaac tccatttaac ttttttcgta
    26881 gtgtgtcttt ttatacatgt ttatcgttat taatagtgaa taggaaaaaa actatttttg
    26941 atcattgaca attaaataca atttttgaat aacgatccct gctattcgag ctagaaactc
    27001 aagtacgcca tgacctgatt agcgacaaat acttagagat ttctttttgt tctgggaaaa
    27061 caaaatgcca tgacaatagc agcaaataat gatacttccg taaggctcgc cgtaaactgg
    27121 ggagaggtga aattcctatg tgcttaccca aagcaattca aaaatttcat aactactatt
    27181 ttaggagatg attttataga atccagagtc tacctgaata aaaaacaaac ctgtgcattt
    27241 ctaggaatcg ataataatac tctagataag tggattcgta tatataattt cccagtaata
    27301 agagttggtg gtgtagttcg ctttgacgta gaagatatta aagactttat gaatacattt
    27361 aaaataactt gaaattttct tctcgccgca tatactaaaa ttagtgaaat atactgcctt
    27421 acttttttta aggagtgagg attttgccta caaagctttc aaatgggaaa tataaaacta
    27481 atctgagata tccaaaaagg tttaaagaaa taacaggaat tgcatcagaa aagtatcaaa
    27541 aaacatttcc aaataggcaa ttggcgatta aagccgaaaa tgatatgaag aagaaaatag
    27601 aaaaagtttt gagagaggag aatgcaaact cattagaatt aaaaggaaaa ataacgttta
    27661 aaaaatttta cgaatctaaa tggcttccta gatatgaatt aggtcaaaca attagatcaa
    27721 acaggcctcc tagtgatata accattagta atacaaaaga tatatttcgg ttgcatattt
    27781 tacctatgtt tggtgaatac gcaatgaatt atctaaatat caatactgag ataatatcag
    27841 atgaattaac caaaaaatcg aaagaatatg caaatataaa aatcataaaa ggatatgttc
    27901 gttccatgtt cgatattgca gaaatactaa attatatcga atttaatcga actactaaaa
    27961 ttattcaaag tatcactgca cctaaaaaaa atgctttaga agaaaaaaga atacaagaag
    28021 gtaagcaagc actatcatca aaagaactta ctaattggat agaagcagta aatgatgatt
    28081 ttaataatca tttacttact tttcatgatt acacactttt tatgattacc ctgtatcttg
    28141 gtgatagaaa aagtgagact tacgctttgc aatggaaata tattgatttt gaaaaacaaa
    28201 cggtccgtct taaacatact ttagataaat atcaaagaaa aaagtttaca aaaggtcgaa
    28261 aagataccgt cattcaagta ccagaagttg taatgacatt gctaagtgaa tggaaatcgg
    28321 tacaagctga tcaattgttg aaattaaaaa ttaagcaaac gttagatcag tatctcttta
    28381 cttatactaa accatctgga gaagtaaatt gtcctgttca tgccgattac ctaaactatc
    28441 gaatcaattc aattaaaaga aggcatcctg acttagttca tttatctcca cacaaactcc
    28501 gtcatactta tgcaactata gctagacaag gtggagcaga tatgaatcaa atttcaaatg
    28561 ctttaacaca ctcagatatt tctacaacaa agatatatgt gaacacacca gatatagttg
    28621 ataaggctgt ttttgaagct tttcagagag gattgaataa gtgtgattga tatgtgttct
    28681 taaatgtgtt cttaaaaaca aaagaagcac tttccaaata attgaaaagt gccagaaacg
    28741 ttgatatata aaggatatta acgttttgag aattgtgaag ctttacgtgc tttcttaaga
    28801 cctggttttt tacgttcgac catacgtgcg tcacgagtaa gtaagccagc acgtttaaga
    28861 gctaaacgga agtcaggatc aacttctagc aatgcacgag cgataccatg acggatagct
    28921 cctgattgtc cagcgtatcc tccgccgttt acgttaacaa atacgtcata tgcgcctttt
    28981 gtttcagtaa cagcgaaagg ttgattgatt acttcacgca agtcagcatg tggaatgtat
    29041 tcttcaacat cttttttatt tacagtaatt ttgccagttc ctggtactag acgtacgcga
    29101 gcaactgcgt ttttacgacg gcctgtgccg atatattgaa cttgtgccaa tgaaattccc
    29161 tcctattaga ttaagtttgt gatgtctaaa acttctggtt gttgtgctgc atgtggatgt
    29221 tctgctccac cgtatacgtt caattttgta aattgtttgc ggcctaaagt gtttttagga
    29281 agcatacctt ttacagaagt ttcgatcaaa cgacgagaat ttttagcacg caattcgcca
    29341 gcagtgattg atttcaatcc tcctgggtag ttgctgtgac ggtaataaat tttgtcagtc
    29401 gcttttttac ctgttaattt cactttgtct gcattgatga cgatgacgaa atcgccagta
    29461 tccaaatgag gtgtgaaagt tggtttattt ttaccacgta gtacagatgc aacaactgtt
    29521 gaaagacgtc ccaatggaac atcagttgcg tctactacat accatttacg ttctacttcg
    29581 cctggtttgg ccatatatgt tgtacgcacg ttattttcct ccaatttaag ttctgatgtt
    29641 tgacatacac ttcgagtttc cggggctctt tgtggggcaa acaataccat ttaacatatt
    29701 acccgctaat ctagtcaatg tcaacgtttt tctgcttgat tgaaaaattt atatgaaact
    29761 ttacttcttt tctttctttt atataaaagg gtcgtttcct gtcaaaatga aaaacaaaaa
    29821 gaggctgtga caaaagtctt gtcacaaccc cttattttga ataaacggtg ttctcctgcc
    29881 aactcctcgg tcacaagtca caatatccat aaaacataag aagctgtttt ttaaaattgt
    29941 ttcttgtgac tcggagctga acggcaggct tacaacctct tggtaaacgg tgttcaatca
    30001 gctgaccctc ggtattagct caaaaaacgg caaaatatga ggaactattt tgacgtttgt
    30061 ttctctaata ctcaggtcaa aacgctgatt tcacaacctc tttttcggtc aagttcaaca
    30121 acagttttta cgcgtcgatc tctggcgctt tgcccaaatg agcttggatc atccagatac
    30181 gtttttctgt ggctgttttg aattcgataa agatatcttg tgttggatcg tcgccttctt
    30241 ctccagaaac ttcgattcct ttttggtaaa gatctgctag ataacgatag cctgcaacaa
    30301 gtgtttccaa acgttctgga atagtacgat cccagcggcc aatttcatca gggatttttg
    30361 tgttatctgc aaattcacgc aatgtagaat aaggtgaacc gtctaatgtg atcaagcgtt
    30421 cggatacttc atctaactga gcgttcaaat catccatgaa ctcatccatc attgggtgca
    30481 atgtaaggaa acctggtcct ctcatgtacc aatgtgtttg gtgaacaaca acagacattt
    30541 ggcttagatc tgcaactaat tgatttaata cttctttggt ttgttggaat ttcatctttc
    30601 ttgcctccta acattttctt acacttaaaa taatagtaga ctttcaatga aaagtacaac
    30661 aaaatcattt acctgagaac gattttcagt tcgctttttt atccgtaaag ccaatcattt
    30721 ttcagaatca gctaattctt ctcgcagttg agcaaattgc tgataagtct gtgctaaatg
    30781 cttttgtgtc gaaacaaata atggatagat tttctgatat tttttatgat cagtttcttg
    30841 tactccaact tgctctttca attctatcaa ttcctgtgct tcactgatac tttggatctt
    30901 tccgatgctt ctccagccta aaatcacagc tcctaatgcg gatgcttctg tgacagtagg
    30961 gaaaacaagc gggtaaccca gtacatcagc catcatctga cgaaaaatcg gagattgagc
    31021 aaacccgcct gtagcacgga tctctgtgag ctgattttcc tggcaaactc cttttaaaat
    31081 ccgataaagg ttgagacaga tcccttctag aatcgccttc atcatttctt tttctgtatg
    31141 ttgccgctgt aaaccgataa aactgccaaa cgcatctgcg tcccaaagcg gtgctcgctc
    31201 accaagtaaa tagggatgaa aaatcagacc attggcaccc gctggcacaa aagcgatagc
    31261 cgaaagcagt gcatcatatg gattttctcc tttttcttta gcagattgaa cgacttcctg
    31321 taaaaatgta tgccctgccc aatcaaagat gccagcacca ttgctagtcg ctcctcccac
    31381 tacccaatgt ttctgatcca gaacataaca aaacgtctcc atttctggat ggaactgagg
    31441 ctgagtagta ataaaacgaa gtgctccgct cgttcctacg gtcaaagcgg cgatcgtatc
    31501 accaaaagca cctaacccta gattagaaag cggcccgtct gcccctccca aaacaaatga
    31561 tatatcattt ggcaaaccta gttctgctgc tgtttttgat ggtagacctg ttacttgata
    31621 ggtggaagga aagacttgcg gcaattgctc tattcgaatg ttcaagtagt caagcacttc
    31681 ttctgcccat tggaattcat ggatatcaaa atatccagtt cctgaagctg ttccgtagtc
    31741 gctgatcagt tcgccaaaca atctataaaa gatatagtct ttgataccga caaaataagc
    31801 agtttttttg aataattcag gttggctgtt ttgcagccac ttgattttgt tcaatggtgt
    31861 cattggatga atcggcgtcc cagtctgccg ataaaattct ttgccaagca cggtatattt
    31921 cagtttttct gcttcgtccg ctgctcggtt atctgcccaa gtgatcattc gagataacgg
    31981 tgttttctct tcatccaaca atatcaggcc atgcatcgca gaggagaagg agacaaattg
    32041 aatgattgtg tctgaaggca actgtttaat tacttctttt ataacggtgc agacaccttg
    32101 aaagatcaat tcctgatctt gttctgccat cccttgtgtt tcttggatca aagggtagcg
    32161 aaaataagcg gatgctgctt cttgggcttc atctgtgaaa gcaactgctt tggtttgtgt
    32221 ggttccgata tctaatccga ttgaaacgtt cattttttca cctcaaattt tatgtatgta
    32281 caaaaattta gtttaagctt gcgtatcttg gttttgaaaa gggggagatg gcgtgttact
    32341 ttattttatc attggttgct gtatcggatc atttttatgt ttaaccgccc agcggattcc
    32401 gttaggtcac tctattattt atcctagatc tcattgtgtc aaatgctgtc gttcgctttc
    32461 ttggtatgaa ttgattccga ttctctcgat catcgtccaa cgatttcgct gccgctattg
    32521 caggtgtcgg ttgcccttct actatttgtt ggcagaagcc ttatgtggtg gtctttttgc
    32581 ctggttcttt actttttctt ccgcaagaaa tttttcgacg ttcatatgga tgctttcggc
    32641 tttgctattt tcgttgatgg atttatttta cttcatggtc cattctcaca cgctattctg
    32701 ttcttgggca attttatgga ttttttggtt gcaggccggc gtcttccaat ggcaaagtgt
    32761 gctgttaacg tttatcgtag gcggtgtgtg ccttcgctat ggtcaatcct atctcggagc
    32821 tggcgatact ctgttgatgc tttcttggag tggtggcttg tctctagaag agttgcttca
    32881 gatcttgttt cttgctagtc tgtttggaat atccgttttt tctgtttact ttatctgtca
    32941 taaaaaaaag ttggaaaagc tgcctttcat tccttttttg agcagtgcgt tgctgattgt
    33001 ccttcatctt aggtattgaa aaaaggttgt gacaaacgac ttgtcacaac ctctgatata
    33061 tagtgttctc ttaccaaatc cttgtgactt ggagctaggc gacaggttca caacctctcc
    33121 actaaatggt gttcaatcag ctgaccctca gtattagctc aaaatgctgg ttttacaacc
    33181 tctgatatac ggtgttccat aagtagcttt ttcggcttct tatttcttga cgccccaatg
    33241 tcgacgaagg aaacctgcac gtccagaacc ttctcgataa agattgtaat ggagcttgtt
    33301 tttcttgtaa taatcctgat ggtaatcttc tgcaggataa aattcgcttc ttggttcgat
    33361 ttttgtcacg attggcttat cgaatcgccc gctgtcttgc aatgcttgtt ttgaacgctc
    33421 tgcaatattt cgttcttctt catcattata gtagatcact ggacgataag aatcaccgcg
    33481 atcagcgaac tgtcctaatg cgtcagtcgg atcggtttgc tgccaataga tttccaccaa
    33541 ctgatcataa gaaataactt ctggatcata ttcgatctct actgcttctg tatgccctgt
    33601 tgtgcctgtt gttacttgtt cataagttgg atttggtaca tgcccgccag tataaccgga
    33661 tgtcacagaa atgatccctg gctgctcttc aaatggtttg accatacacc aaaagcatcc
    33721 gcctgcgaaa actgcttttt ttgtcatata aaatccccct tttttctcat cataccttga
    33781 tttccaaaag gaggataacg ttttgcttgt gacagaaaaa acggaaacta ttatatacgt
    33841 gatacggctt ctgataaatg ccaaaacgaa cgtacttgat caaaaacggt taaatcagga
    33901 atcacatatt cagcagaagg aagatttatg ttttcaccta ttcccaatac atgcatgtta
    33961 ccagccaaag ctgcttgaca accagcttct gaatcttcaa tgaccaagca tgcatttggc
    34021 ggtacattca attgctgtgc tcctttgaga aaaacttctg gatcaggttt tgcttttgat
    34081 acttgcgtgc cgtcaataag gacatcaaaa taacttgtca aattcgtttt ttctaaaatg
    34141 aggcgtgcat ttttgcttgc tgatcccaat ccgatcttga tgtttgtttt tttcaagtac
    34201 tcaagaacag ctattgcacc aggcaaaacg gatgtttcat ccattttttg aatcgcttga
    34261 agatatagat tgtttttttg ctcagcaaag gctgatttct ctttttctga gaatttctgt
    34321 tccatttttc caaatgacag caatcgctct agtgactcgg ttctggatat tcctttcagt
    34381 tgctcgtttt ctttctcagt gaatggaatg gacagctggt tagctaaaac cagccacgct
    34441 tcgtaatgat aacgagctgt gtctacaaga acgccatcta aatcgaatag tgctgctttg
    34501 attttcatcg attacctcct tgaaaatgaa cgacttgaag taaagatgcg atgtttttag
    34561 ctgtgcgatg aagattatca gtggcttgct gtaaagcttc ttgtaaaggc acagctgcag
    34621 gaaggatcgg aaaaacggcc gaaatgccaa catctgctgc tttttcgctt cctttaccaa
    34681 cacttccgca aatagctatc acaggaacgc cctctggtac tcttctagca atcccaactg
    34741 gcgcttttcc ttttagactt tgtccatcta gacgtccttc gcctacgatt acgaggtctg
    34801 cttgctgtac ccgtttatcg aactccagta aatccaatac gtagtcgatg ccagagacta
    34861 ttttccctga agcaaatgct aacagtcctg cacccattcc accaccagca ctactgcccg
    34921 atgcctcgat tacttgaggg gcaaatctca tataaaaatc atgcatggct tggtcagcca
    34981 ctgctaattc attttctttc aagccttttt gtggtccgaa aacaaaagaa gcgccttctt
    35041 ttccgcataa aagattagta acatcagtaa tgacagtgat tttggcttta atcagctcaa
    35101 taggcacgtt cgttttatca actgtagcaa ttttacctag attttctccc agtgcttcta
    35161 ctttttgatt atcttgatcg taaaaagcat aacctagacc ttctgccatg ccgatgccgc
    35221 catcgttggt actacttccg ccaacgccga tgatgatgtg tcgaacacct tgttgcaaca
    35281 attgtcgtat cagttctcct actcctcgcg tggataacct aagtggctgt tgttggttta
    35341 gtgggacatc tttcaatccg acgatttctg ccatttcaaa aatcgcagtt tgaccgtctg
    35401 aagcgtactg gatttctttg tttttgccaa atgcattagt aacgactgct gtttgccgct
    35461 tcaaccttaa actgtctgct aatgatgaaa ccgttccttc tcctccatcg cctataggta
    35521 gcagatcata ttcagcctga acaaaaactt cttgaaaacc tgattgaatg gcttgtgctg
    35581 cctctaaggc tgtcagactt tctttgaaag aatctggcgc aatcagaata cgcattattt
    35641 tcccctccgt tccaagatca gttctttttc cagctggtat tggtctccat tgacaaaaat
    35701 aggtaatgtt tctttcgtct ctttttttat tactatttgt ttttttgtca aaacaaatag
    35761 caacctgtga tttttccaaa taaaaggaaa agaaattttt tcccatgctg aaggaagtct
    35821 tggagaaata gaaagagttc cattcgttac tgtaatacct gaaaaaccaa atataactgc
    35881 tagccatagt gctcctaatg aagcagcatg aattccgtca tctgatgaat gcggatctgg
    35941 tcctaaatca atcaggcacg cttcttggaa taaatgatac gcccattcca tttcttggat
    36001 acggcaagcc tctatggcgt gaatcgcttt actcaacgat gagtcgtgga ttgttttgtt
    36061 ttcatagtaa tgcaaattct tagaaacgat tggttgagaa aaatactcag gtaataagta
    36121 taacagcatg acaagatctg cttgcttgct gacttggagt tcatttactt cgctacgggc
    36181 ataatcaagt aaaatagact ggctgccagg acgttctttg taagtggtca aatcaataac
    36241 tggcttactg agatacgtgt catcttgcgg aatcagctgt tctttgttag gcactggcaa
    36301 atataactta tctaaaaaat tttgacattc tttcaaaaaa agcggatcgc cagcttgata
    36361 tttaacagct aaggccacat tataatgcgc cagatagttc gtatatgcat tattgtcgat
    36421 atattctgtg tattcatctg gaccaatgac tctgtgtatc tctaaatgat catcgacttt
    36481 tacagctctg ctcagccaaa aagctgctgt ttcatgaatg agcgtttttc cctttgtttc
    36541 taaaaacgat tgatcctctg ttgcttggac atactcttga acggcataag caaggtctgc
    36601 actgatatga tgttctgcgg cagctgaagc aacttcttgt cttgttccgg ttttgatatt
    36661 caatgcagca aatttgggtg tctcttcctg accagtgtgt gcgctttccc atgggaaaag
    36721 tgcaccttga tagtgataat ctcttgcttt ttgccgtgcg ccttctaatc gatcataacg
    36781 gtacagcagc aaattctttg ctacttcagg aaactgatat aaaaagaaag gcaggataaa
    36841 aatttccgta tcccagaaaa catgcccttt ataaccttcg ccagttagtc ccttcgcccc
    36901 tacactaaca cttggatcat tgcggggagt cataatctgt aaatggtaag cagcgaagtc
    36961 catcgctaac tgatcgaaag aagaatcgcc ttggatcgtt atccgatgct gatgccaaaa
    37021 atctgtccaa taagacatcg actgctctaa aatttctgta taactaacgc ttttctgggc
    37081 ttgggcaata cttttcttaa acgggtctgt ttgctgaaga gaggtagaga gcacgatgat
    37141 cttctccagc gtaaaggacg tattttttct gatcttttct gaaaaggaag cggtgatccg
    37201 gcgatttttt gcttggaata cacctgcttt attgaattta gctgcaatcc caatatcaat
    37261 tttactttct gttgtctggt aggatgcact gatcaaatcg tcaccaaata ctcgcagttc
    37321 tttttcaacc aactgctgtg taccaaaatt ggtttgctgt ccatcgatac ccgttttcac
    37381 atctacttgg cagtcttcgg tcaacggctt gatgaccact ttcagggctg cctgatggag
    37441 attattttga tcagcaacac gacaagtaat gacttccact ttttttcctt gagcagtttc
    37501 aatgagcgca tagcgtttaa gctctcccat ttctaaatct agtgcccgct cgtatgcaag
    37561 aactttcatc gtctcaagag aaaaatgttc accgtcgatt tttatttccc atctgatgac
    37621 atctgggaga ttcactaact cggctgattc tgctcctaaa ggtcggttat atacaccagc
    37681 tgcaaacatt ccccttactt gattccgata gtcttcctcc tggcttcctc tgataccaaa
    37741 aaatccattt ccaatggtca tctgactcgc atacttattg atatactcta aatcaaactg
    37801 tttttcttct actttcataa ggtaataact tctcctgttt ctgccgaacg atataaattt
    37861 tccaccagat tctggatgac atatccttgc cagccatctg caatcatctg agtctggtca
    37921 ccgagcgccc gattcacaaa atgagccata cttagttcat gtgggtcatt aactggcgtg
    37981 gtcttttgta aggaaaccag ctttccatct acatcttcga atagttcgcc tggatacaga
    38041 ttagcacctg cctgatcgcc acaaaaagcc acattcagtt tgtcttctct gatattcaaa
    38101 gcaaacgaag tattcagttg gatgatcttg ccgttttcta attccagtgt gccaaaaatt
    38161 gcatcttcta ctgtgaattt gcttggatcc catttcccga atttccctga attttttttc
    38221 gtaccaattt tttggaagct gtacgcccga acgcttttta ctttaggaaa tccagtaata
    38281 tacatcgctg tatcaagcat gtgaatgcca taatcgatca aaggcccgcc tccttgaagt
    38341 tctttgtcga taaacgttcc ccagcctgga acaccagacc gacgaagcgc attcgcttct
    38401 acgtaataaa tatccccgag aacatcaaga tgattcttga tcattgttgc ttcgtcagaa
    38461 aaacgatgct ggaatccata agccaaaatc tgcccgtttt tatcggctgt ctctgccatc
    38521 tttcttgctt gatcagctgt catagctggt ggtttctcgc acatcactga agcattagct
    38581 tcgagggcag ccaatacatg ttcgaagtga aagcgattgg gtgtacagac actcacgata
    38641 tcgggagaaa tctcattcag catttgtgta actgatgtat acgcatgaga aaatcctgta
    38701 cgtcggcaaa agtcttctgc tcgctggctg actggatcaa ccacagcggc caattctaag
    38761 acatctgatc ttttttgata ataagcagca tgtacttttt ctgctacttg tccagcgcct
    38821 atgattgcta ctttcttcat ttatttctcc ctcctttgct tatttactta ttgttattct
    38881 ttctctattc tttctctaaa tcatttaaat gacgcgctgt ttccagacag tttttcaagt
    38941 attgcaatga ttcctgataa attttcactt cattttctcc tcgcaaacga cattcatata
    39001 ccatataacc ttcatactca ttttgaagta gcgtttgaaa atggcgagta aaatcaattg
    39061 cgccagatcc tggttggtag cgatgattat ctgctaaatg gatatgaccc acatactctt
    39121 tttgcgtagt caatgctttt gaaatatcat cttcttcaat attcatatga taaaaatcag
    39181 cgatgatctg cacatgtttc aattgattag agtcaatgta atgacgcgca tccgctaaca
    39241 aattgatcat atggtcttgg tatcggttca aaggctccaa ataaataacc gtacctgttt
    39301 cttcggctac tttatctaaa taacgaagtg attcgctgac tgctttatag tctccttctt
    39361 tgcttcgggg tgaaaccatc ggcggtaatc gataagtgaa cattccccaa gctgctggga
    39421 taacgattcc tttgcctcca acctcgctta gtgcacgcaa aatctcagca atttgacgta
    39481 caccattaag acgccgttct tcgataaagt caccgatcca cccatcgtag ccgttacaag
    39541 ctgtcactac tgggatccct gtttctttga ttgcctgttt gactgtgtcg atattttcta
    39601 ttaacaactt accgtcgatt tcgtattctt caaatccaca gtctttgata aatctaaatt
    39661 tttctaaaat gtctcttggg aaaaatgctt gatcttgcgt accgaatttc attgttctcc
    39721 tcctcggact tgaacgccca ttttgatact ttcttctggg tgctggtcta cataacgcat
    39781 gtaagcttct gcgctttctg caaatggcac aactggatca atgatttctt cacaatccaa
    39841 gtaaccgttc atcaataatt cccaacatgt gtcctcgatt cgtttacggt tccatcttgg
    39901 gtaatctggg tttggttcac tagatgctcg agcaaagacg atttttgcat tattgaaatg
    39961 tgcttcgcga ccaagattaa acccagctgg aaaaggttta gcaaaggcaa cataagaaat
    40021 gatcccgcca tagccgatcc ctcttaaaga agcttgtaat gcggcagcac tgccactcgt
    40081 ttcaataact gaatctactc cacgtttatc tgtcaattcc tttagacgaa aaccgacatc
    40141 tgctttcata ggatctagcg tgtaatcggc accgtatttt tctgctaatt ctctacgctg
    40201 cgctatggga tcgatcccaa cgatggtagt agcacctgct tttttagcta attgaatcgc
    40261 aatttgcccg atagcgccta aaccgaagat tgctacagca tcacctgctc gaacatgtgc
    40321 ttcccggata ccacctaaag cgaattgagc aggatcgtaa catactgcat ttttccattg
    40381 atccaaccga tcaagtttac gtagtttata attatcaaca ccgtttgtaa tcagcgtttc
    40441 acgaatgggt ccataagtgc agactaactc tcctttttga tactctgtca ccaaactgcc
    40501 cgtttcttcg atcgtaccga caatcatatt tcctaattga aattcgccaa ataccacacc
    40561 gcgttggctt ccttcttctc ttggcaagaa taggcgccat tcttctgaaa attcttcatc
    40621 gataaatgga cttaatcctc taaagtcgac aatttctgtt cctggttttg gagtagcgaa
    40681 aattactcgg atacgtactt cgttcttttc gatctcacgg tcttcgtaat ctttgaatcc
    40741 ggctattctt ggttctaatg caactaattt tttcatcttt tctttcctct ttcttttctt
    40801 tttatccttt tacgccgcct tcgactaaat cacctttaat aaatcgttca gataacgcat
    40861 acataatgat gactggtaaa gcggtcacca atgaagcggc catcattcgt ccccaaatgt
    40921 agtctggtgt actgaataat gtgttcaaac cgattggtaa agtaaatttt tcggaggtcg
    40981 acaggaaaat cgaagcaaat aaataatcat tccacgaaac cataaagcaa taaacgaaga
    41041 cagaaatgat tccagaaata gccaatggta taatgatccg aataatgatc tggatccggc
    41101 taagaccatc gatcattgct gcttcttcaa tatcagtcgg aatcgtgtca aaataacttt
    41161 ttagcatgaa tatcgcagta ggaagtgttt gaacgaccat cgtgataatc agtgctgtat
    41221 tggtatcata caaacctaga ccggaaatga ttttaaataa tggaacaacg atcaaaatac
    41281 cggaaaacat ataaacggtg taaaagctag cattgatttt cgagcgagct ttgaagcgta
    41341 gttttgacaa agcgtatgcc ccgctgatcc caatcactac tgcagttacg gaggctatca
    41401 aggagatcac taaactattt ttgaaataca tgatgaatgg aaaaatctca gcattgaaaa
    41461 tatcctgata atgttcaaaa gtccattctt tcggaaaaat agtttgtgtc gttgcaattg
    41521 cttcttgtga atccttgaat gatgtcatca gcatgatcaa aaatggaaac aaattgacag
    41581 ctaatagcaa caaaatcgtc gcgtaaaata agattttcct gctcttttta tttttcattt
    41641 caagtccacc ttctttcgtg agagcaagac gaccgctgca ataatgatga acaatagaat
    41701 cgatatagct gctgcttttc caagatcatt gaacgcaaag gctgtctgat acaaataaac
    41761 gcctaagata ttgactttat tcgtcagtag atagacatct gtaaacatat agaacatcca
    41821 gatagatcgt aaaacaatca cagttgctag tactggtttg attgccggca gtgtcacgat
    41881 cttgaacttc tgccaagcat ttgcaccgtc catttcagct gcttcataaa gcgttttgtc
    41941 gactgtttgc aaaatagcca aaaatgaaat aaacgcatac ggatagtatc tccagatagc
    42001 aaacaaaacg accataaaga agctagcaac tggctggtcg aaccacagcg gtgcttcgtt
    42061 gaaaagctgc aacctatcta ctaacagatc attgacgatt ccataactat tattgaacat
    42121 atatttccaa gcaaaaatca aagaaataga tggcgtaaca taacttaata aaatcagtga
    42181 acgcaccgtt ttcctaaatc tgaacttgcg gttaagcaaa atagctacgg ctaatcctaa
    42241 agctgtactg cctgctacaa ctaagaatgt gtaagcaact gttaaaccta aagaacgata
    42301 aaattcacta tcacttaaaa tttcaagata attgcttaat ccgataaaaa cggcgtctga
    42361 gttaggattc agcggcatat cgaaaaaact gatctgaata ttggaaagca ttggaatcag
    42421 cactaaaaca gctaataaaa gcatgcttgg tgctaaaagt cccatggcta attttaagtc
    42481 agaatgtttc cttggacgat tcattgaaac ctccccctga taatctgcca atagctatct
    42541 acttttttcg aacaccattg gcagaacttc ttgttatttc gtattttttt gtgcgtcagc
    42601 taaagcttga tcgacatctt cgtttccgac agttacttgg ttcactgctt ttccgatcac
    42661 acctgagctt gtgatatctc ccattttcgt gaaattcttt tccccgacta gtccaaagac
    42721 ttgtacttca tcaaaagcac tagcaatctc agatggcagc tcgccaaaag acttgatgac
    42781 ttcattttct ttgtaaccat ccagttcgac tacttgttta ttcactggtt gagcaccacc
    42841 aggagacatc aagacccact tttccatgtt tttcggttga gataagaaag ctgtgaatgc
    42901 ttcagcagcc tctttttgtt tctcgtctag accagaagaa atcgtcaatc cagatactgt
    42961 gccatagaca gcttgatctt tttgtgttgg gatagcaaaa ccgatatttt ctgagttccc
    43021 cgcttcataa acagaaggca aaatgtaagt tgaatagatt gccattggtg ctgttccatt
    43081 catgaaagca tctttgattt ctgtcacatc attagagcct ggcatcgtgt attgggataa
    43141 gttttgataa aacgacaatg cttctctcat cttttccgta tcgatcgtta cctcgccttc
    43201 atcatccaaa acatttgctc catttgacaa agcaaattga gagaacgctt gctcactcat
    43261 tgttccttca gcagtaggca tagcaattcc atattgttta ttctctttat ctgtgaaatg
    43321 ttgagcaatt tttaaaatat catcccaatt ttctggttct gaaaaaccag cttctgataa
    43381 tttttctttg tcataccaaa taccttgaac ccagccgcta attggtgcag caatatagct
    43441 ttttccatct tctgaacgaa caaggttttt ggctccgtca taataattat cttctccagc
    43501 ttcctcgata acgttttgga ctgccgtctg atcaatcagt tcatctttat ccatcacttt
    43561 agcaaaatcc tgactgactt ccattacttc tggtaattta ccggaacgag ctaacgtaac
    43621 gatttttgta ttgaacgctg attcttctac cggcacttgc ttgattttga tgtctggatt
    43681 ttctttttca aaatcagcaa ccagttcatt gatcacactt aatcgttcct gttcgacaga
    43741 agagtgcatg aattgaatcg ttgtctgttg tgattcgtta gagctttgac tttcaccaca
    43801 agcagtaaga agaaatccag tagctagcag acaggtagta acaataattt ttttcatttt
    43861 tttccacctc ttattttatt attttcagcc acatatattc atacggctgg aatatcaact
    43921 ttcgttcttg actgcaatgg ataatttgtc cagaaaacag gtctaggtaa tctccttttg
    43981 gtaaaagata acctgctgat tgattggaaa aattatggat aactaagact ttctcttcct
    44041 tcgcttcgcg aataaaactg ataaaagaat ctgctgagtc cagtaagtaa atcaaactat
    44101 tcggatggaa ggctttttct ttttttcgaa tagatagcat ctgggtcaat tcaccatata
    44161 ctgctgttct taatggatct gtctgcaact ctttctcaat atctgctaac aaaaattttt
    44221 gccgattgat ttttcgattc tctcctgttt tttctacgcc tttgtaatca tttcgacttc
    44281 ccagcacact ttgaatataa attgccggca cgcctggtaa cgttaccaaa aatgaatgag
    44341 cagctaaaaa gcgtttgctt ctccattccg tcgtatctgt tggagaactt aacgcatcta
    44401 gatacgtagc gtttatctca tatggactgg tcgttccatc tgggtttttc ttgtagttta
    44461 ctcgggtacc ctctttcttc agctgttcca ctaattcaag gatcgttttt tccggcagaa
    44521 tacctcgtac cggattcaat ccgataccgt catgggaggc taaaaaatta aaaaaagttg
    44581 tttttttcga tgcgaaatcg atggttttta accattcttt caacttactt gtattacccg
    44641 aacgaatcgc ttgaagggtc aaaggtggta gcgaaaactg atagaccatc tgtgcttcat
    44701 tctcgccatt cccaaaataa ctgatattat ctttgtgtgg cacatttgtc tcagtgatca
    44761 ataccgttcc tggagctgct tcatcagcga ttgcacggaa taattggatg attttatgcg
    44821 tttctggcag gtgtatacaa gaagttccta gttctttcca taaaaatccc acagcgtcca
    44881 agcgaataaa tgaagcgcct ttttctaagt aaaacaaaag aatatcgatc attttcaata
    44941 aaacttctgg atttttaaaa ttcaagtcta cttgatcttc gctaaaagtc gtccatacgt
    45001 gtttttcttt cccgtttttg tcaatgaacg ttgtaagtaa cgggctggtc cttggtctag
    45061 tcacgctgct tgtatctgta tccagtggca aatcaataaa aaaatctttg tacgtatcat
    45121 tcaagtttaa atattcctga aaccaagtac tttcggcaga catatgattg cagacaaagt
    45181 cgaacattaa ccgtgtttcg cttctcattt cttctatatc ttcccatgtg cccaaacggt
    45241 cgttgattgc ctgataattt acaacggaga aaccatcatc agatgtatat gggaaaaatg
    45301 gcaagaaatg tacaactcta aatgtatctg ccaaatactt ttgataaaat ttcttaaatg
    45361 tacgcaaagt tggttgctgc tcttcaaaaa attgatcccc ataagtaatc aagaaaatat
    45421 cttcttcgtc ccaatgcagt ttgcctgcct ggcctttctt ctgctgataa acactgactt
    45481 tttgttcaat catagaggcg gttttctcag acaaatctga gtcgcgataa atcgcttgta
    45541 aaagttttgt atacatcgga ttcccctttc ttttttggga gcgttcccaa cgatttgatc
    45601 atattatgga aaacgcttac tgtcaatagc atttttttaa ataattttga tatacacaaa
    45661 aatacaaata agaaagctta tgtatcaata attaatagct tcttaaaaaa atatggtctc
    45721 tcatgatcat gcaagctatt cctaaatttt caaaatcata gacaaaaaag aatgtctatt
    45781 gtactatgga attattctaa aacgctccca aaaaggaggt gcatataaaa ttgaaaccta
    45841 ctatttatga cattgcgaaa aaagctaatg tctcaaaatc aactgtctcc agagtattaa
    45901 ataaccagcc aaatatctct gataaagcaa aagcaagtgt acttcaagca atcaaagaat
    45961 tgaattatga accgagcaaa attgcaagag gactgtcagg aaatggtttt gacgcgattc
    46021 tagcattatc tcatcgtact tctcatacga cctatggcaa tccttttttt tcagatgtta
    46081 ttcaatccat ttctgccgtt tctgaacaaa ataacttcga cttgattcta caaacggcaa
    46141 aaacaccaga agaagagcta gaaaaatgcg cgaaaaagat ccaagaaaaa atgatccgag
    46201 gaattattat tttaagctct acgatggatg aaacacttct ttttgaattg gatcaataca
    46261 atattcctat tgtggtaatc ggaaaagtcg gaaacgacta cacgaacatc tactcagtgg
    46321 acacggataa tttccaggat agttacgatt tggtggaaac actgatcaag aatggacacc
    46381 gtcatatcgg ctgtctccat gctccgacag aagtttatgt atccaatgat cgtctcaatg
    46441 gttaccgtca atgcttattt gatcaccacc tagatatccg taatgaatgg attatagacg
    46501 gcggctttcg cttagaagat agcatggcag caatgaatga tttaatgaag ctacgagaaa
    46561 gaccaactgc gattttttct accgatgcat taaaatcatt gagtatttac aaagtggcag
    46621 aacaatctgg aaagcagata cctgatgatc tttcgatcgc aggattcagt gatcccttat
    46681 tgtcctccct attttcgcca cagttgactc ggatagacat tccgacaaat cagttaggaa
    46741 tcaaagccac agaactttta ttccaactaa tccaccacca ataccctgaa gaaaaaagaa
    46801 tcattctttc aaccgagatt actctcacag attcgatcca acaacaagaa atgtagaaca
    46861 gaattataaa agaacagaaa cactgaggat aagtcagtta ctctgttctt ttttcaatca
    46921 ctcatccctc gttaccccct cccggtattt tagcgaattt ttcttatttt ccatctgttt
    46981 tagatagctg tggataacta taatgtttgt gttaaactat tttttccaca gggaagaaaa
    47041 aactattttt aaccacgttg tgtataagtt tttatagttc gtttttttaa acacatttac
    47101 ccttatttca atccatgtta tttggggata cttatctcta aaacataaat agaataacag
    47161 acatgtctac tggttttgtt ttattcgagg aattattcaa taatagctag caaaatatta
    47221 aaaataaccg ctctatcttc ccatcaattt attttgcatt caaaaaatga tctatcttta
    47281 cttttgttga ttgacttctc ttggaagatg atcgttccga taccttaatt ggatacgaac
    47341 cgatgttgtt aagatccttt cccacttttc ttctagttag acaaattatt ttagac
//
LOCUS       DAFLVO010000014        45355 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.014, whole genome shotgun sequence.
ACCESSION   DAFLVO010000014 DAFLVO010000000
VERSION     DAFLVO010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.014"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            36..2633
                     /gene="adhE"
                     /locus_tag="L1U99_000830"
                     /gene_synonym="adhC"
     CDS             36..2633
                     /gene="adhE"
                     /locus_tag="L1U99_000830"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBN1211392.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            2862..3968
                     /locus_tag="L1U99_000831"
     CDS             2862..3968
                     /locus_tag="L1U99_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBN1211393.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            3985..5013
                     /locus_tag="L1U99_000832"
     CDS             3985..5013
                     /locus_tag="L1U99_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HBN1211394.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            5019..5498
                     /locus_tag="L1U99_000833"
     CDS             5019..5498
                     /locus_tag="L1U99_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HBN1211395.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            5514..6809
                     /locus_tag="L1U99_000834"
     CDS             5514..6809
                     /locus_tag="L1U99_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HBN1211396.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            6820..7644
                     /locus_tag="L1U99_000835"
     CDS             6820..7644
                     /locus_tag="L1U99_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBN1211397.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            7809..8708
                     /locus_tag="L1U99_000836"
     CDS             7809..8708
                     /locus_tag="L1U99_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1211398.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(8834..9703)
                     /locus_tag="L1U99_000837"
     CDS             complement(8834..9703)
                     /locus_tag="L1U99_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HBN1211399.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            9856..11316
                     /gene="rhaB"
                     /locus_tag="L1U99_000838"
     CDS             9856..11316
                     /gene="rhaB"
                     /locus_tag="L1U99_000838"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HBN1211400.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            11313..12569
                     /gene="rhaA"
                     /locus_tag="L1U99_000839"
     CDS             11313..12569
                     /gene="rhaA"
                     /locus_tag="L1U99_000839"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HBN1211401.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            12583..13428
                     /gene="rhaD"
                     /locus_tag="L1U99_000840"
     CDS             12583..13428
                     /gene="rhaD"
                     /locus_tag="L1U99_000840"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HBN1211402.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            13430..13741
                     /gene="rhaM"
                     /locus_tag="L1U99_000841"
     CDS             13430..13741
                     /gene="rhaM"
                     /locus_tag="L1U99_000841"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HBN1211403.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            13823..14974
                     /gene="fucO"
                     /locus_tag="L1U99_000842"
     CDS             13823..14974
                     /gene="fucO"
                     /locus_tag="L1U99_000842"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HBN1211404.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            15101..15859
                     /locus_tag="L1U99_000843"
     CDS             15101..15859
                     /locus_tag="L1U99_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBN1211405.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            15959..16603
                     /locus_tag="L1U99_000844"
     CDS             15959..16603
                     /locus_tag="L1U99_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HBN1211406.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            16610..17617
                     /locus_tag="L1U99_000845"
     CDS             16610..17617
                     /locus_tag="L1U99_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBN1211407.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            17633..18475
                     /gene="kduI"
                     /locus_tag="L1U99_000846"
     CDS             17633..18475
                     /gene="kduI"
                     /locus_tag="L1U99_000846"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HBN1211408.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            18495..19298
                     /locus_tag="L1U99_000847"
     CDS             18495..19298
                     /locus_tag="L1U99_000847"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HBN1211409.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(19547..20611)
                     /locus_tag="L1U99_000848"
     CDS             complement(19547..20611)
                     /locus_tag="L1U99_000848"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HBN1211410.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(20608..21693)
                     /locus_tag="L1U99_000849"
     CDS             complement(20608..21693)
                     /locus_tag="L1U99_000849"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HBN1211411.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(21706..22683)
                     /gene="mvaD"
                     /locus_tag="L1U99_000850"
     CDS             complement(21706..22683)
                     /gene="mvaD"
                     /locus_tag="L1U99_000850"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HBN1211412.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(22676..23620)
                     /gene="mvk"
                     /locus_tag="L1U99_000851"
     CDS             complement(22676..23620)
                     /gene="mvk"
                     /locus_tag="L1U99_000851"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HBN1211413.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            23936..24595
                     /locus_tag="L1U99_000852"
     CDS             23936..24595
                     /locus_tag="L1U99_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBN1211414.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            24680..25585
                     /locus_tag="L1U99_000853"
     CDS             24680..25585
                     /locus_tag="L1U99_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBN1211415.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(25587..26219)
                     /locus_tag="L1U99_000854"
     CDS             complement(25587..26219)
                     /locus_tag="L1U99_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBN1211416.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     misc_feature    26370..26495
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            26539..27063
                     /gene="infC"
                     /locus_tag="L1U99_000855"
     CDS             26539..27063
                     /gene="infC"
                     /locus_tag="L1U99_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBN1211417.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            27135..27335
                     /gene="rpmI"
                     /locus_tag="L1U99_000856"
     CDS             27135..27335
                     /gene="rpmI"
                     /locus_tag="L1U99_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBN1211418.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            27388..27747
                     /gene="rplT"
                     /locus_tag="L1U99_000857"
     CDS             27388..27747
                     /gene="rplT"
                     /locus_tag="L1U99_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBN1211419.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            27999..29336
                     /locus_tag="L1U99_000858"
     CDS             27999..29336
                     /locus_tag="L1U99_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HBN1211420.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            29384..31513
                     /locus_tag="L1U99_000859"
     CDS             29384..31513
                     /locus_tag="L1U99_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBN1211421.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            31488..32177
                     /locus_tag="L1U99_000860"
     CDS             31488..32177
                     /locus_tag="L1U99_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211422.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(32585..33262)
                     /locus_tag="L1U99_000861"
     CDS             complement(32585..33262)
                     /locus_tag="L1U99_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1211423.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTRFRWLR
                     LTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDYFED
                     IQDRPIK"
     gene            complement(33398..33592)
                     /locus_tag="L1U99_000862"
     CDS             complement(33398..33592)
                     /locus_tag="L1U99_000862"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211424.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(33642..34082)
                     /locus_tag="L1U99_000863"
     CDS             complement(33642..34082)
                     /locus_tag="L1U99_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HBN1211425.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(34086..34931)
                     /locus_tag="L1U99_000864"
     CDS             complement(34086..34931)
                     /locus_tag="L1U99_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HBN1211426.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            35080..36498
                     /gene="pepV"
                     /locus_tag="L1U99_000865"
     CDS             35080..36498
                     /gene="pepV"
                     /locus_tag="L1U99_000865"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBN1211427.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(36555..37502)
                     /locus_tag="L1U99_000866"
     CDS             complement(36555..37502)
                     /locus_tag="L1U99_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1211428.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(37725..38075)
                     /locus_tag="L1U99_000867"
     CDS             complement(37725..38075)
                     /locus_tag="L1U99_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBN1211429.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            38275..39354
                     /gene="pepA"
                     /locus_tag="L1U99_000868"
     CDS             38275..39354
                     /gene="pepA"
                     /locus_tag="L1U99_000868"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HBN1211430.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            39498..39818
                     /locus_tag="L1U99_000869"
     CDS             39498..39818
                     /locus_tag="L1U99_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBN1211431.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            39840..40304
                     /locus_tag="L1U99_000870"
     CDS             39840..40304
                     /locus_tag="L1U99_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBN1211432.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            40509..41114
                     /locus_tag="L1U99_000871"
     CDS             40509..41114
                     /locus_tag="L1U99_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HBN1211433.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(41153..42442)
                     /locus_tag="L1U99_000872"
     CDS             complement(41153..42442)
                     /locus_tag="L1U99_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBN1211434.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            42870..43349
                     /gene="rlmH"
                     /locus_tag="L1U99_000873"
     CDS             42870..43349
                     /gene="rlmH"
                     /locus_tag="L1U99_000873"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBN1211435.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            43552..44102
                     /locus_tag="L1U99_000874"
                     /pseudo
     CDS             43552..44102
                     /locus_tag="L1U99_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299296.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
     gene            44173..45342
                     /locus_tag="L1U99_000875"
     CDS             44173..45342
                     /locus_tag="L1U99_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfa13 family transposase"
                     /protein_id="HBN1211436.1"
                     /translation="MNDFTTEIMEILINKGDLDDLFRRHLELAINALLQAELTVFLDY
                     EKYDRAGFNSGNSRNGNYSRSFKTEYGELNLVIPRDRNGDFSQQTLPAYKRTNDSLET
                     TIIQLVQKGITMSEISDLIEKMYGHYYKPQTISNMSKIVSEDVSAFKERTLEAKYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFTIAPTESAYVWKEILQDLKDRG
                     LEEVLLVVTDGLSGIDDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
BASE COUNT        14454 a         8192 c         9636 g        13073 t
ORIGIN      
        1 ttaacaaata accatgaccc attaggagga taatgatggc taaagtaata gaaaaagaaa
       61 aaacgaagac aattgacgta caagcaatga ttgatgattt ggcagaaaaa gcaaatgcag
      121 cattgaaaga aatggaaagc tttgatcaag aaaaagtaga ccatatcgtg catgaaatgg
      181 caatggcagc tttggatcaa catatgccat tagcgaagat ggctgtagag gaaacaggcc
      241 gcggtgttta cgaagataaa gcaatcaaaa atatgtatgc gtccgaatat atttggcata
      301 atatcaaaca tgataaaaca gttggtgtga tcaatgaaga tgtccaaaaa gggttgattg
      361 aaattgctga accagtcggt gtggtttgcg gagtaactcc aacaacgaat ccgacttcca
      421 caacgatttt caaatcaatg atcgcgttga aaacaagaaa tccaatcgtt tttgctttcc
      481 atccaagtgc ccaaaaatct tctgcagaag cagcacgagt ggtacgtgat gctgctatcg
      541 ctgccggagc tcctgaaaat tgtatccaat ggatcgaaca tccttcgatc gaagcgactt
      601 ctatgctaat gaaccatcca ggtatcgcga tcgtcttagc gacaggtgga gctggaatgg
      661 tcaagtctgc ttactctaca ggaaaaccag ctttaggtgt aggtccaggt aacgtaccag
      721 cttatattga aaaaacagca aaaattaaac gtgcagtgaa cgatttgatc gtttcgaaaa
      781 catttgataa tggaatgatt tgtgcttctg aacaagctgt gatcgtggat aaagaaatct
      841 atgcagcagt aaaagcagaa ttccaagcac accaagttta tatcgtaaaa ccagatgaat
      901 tgcaaaaatt agaagatgca gtgatgaacg aaggaaaata tgcggtcaat ccatcaatcg
      961 ttggacattc tgcgatggaa atcgcaaaat tggcaggaat cagtgtacca aaaggaacga
     1021 aaatgctgat tgctgaattg gaaggcgtag gcccagatta tccgctatca agagaaaaac
     1081 tttctccagt tcttgccatg atcaaagcta acaacacgga ccatgcgttt gatttgtgtg
     1141 aaggtatgtt gaatcttgga ggattaggac atacagcagt tatccattca gaaaacgaag
     1201 agttgcatgt caaattcggt cttcgaatga aagcttgtcg tattttagtg aatacaccat
     1261 ctgcagaagg cggcatcggt gatatctata acgaaatgat tccgtcattg actttgggat
     1321 gcggttctta tggtaagaac tctgtttctc gtaacgtctc tgctgtaaac ttaatcaatg
     1381 tcaaaactgt agcgaaacgg agaaataaca tgcaatggtt caaattaccg ccaaaaatct
     1441 tctttgaaaa gaactctcta ttgtacttag agaaaatgga aaacgttgaa cgtgtcatga
     1501 tcgtttgtga ccctggtatg gtccaattcg gttactgcga tacagttcgt gaagtattgg
     1561 cacgacgtaa aaatgatgtg aagatcgaag tcttctcaga tgttgaaccg aacccatcga
     1621 caaataccgt atacgcagga acgaaactga tggcagactt caagccagat acagtaatcg
     1681 ctcttggagg cggttctgca atggacgcag ctaagggaat gtggatgttc tatgaacacc
     1741 cagacacatc tttctttggt gcaaaacaaa aattcttgga tatccgtaaa cggacatata
     1801 agatcgacaa accagaaaaa acacaattcg tatgtatccc gacaacatca gggactggtt
     1861 ctgaagtaac gccatttgcg gtcatcactg acagtgaaac acatgtgaaa tatccgttag
     1921 cagattatgc attgacgcca gatgtcgcaa tcgtcgatcc tcaattcgtc atgtcagttc
     1981 cagcatctgt cacagcagat accgggatgg atgtgttaac acatgcaatc gaatcctatg
     2041 tttcagtcat ggcttcagat tatacacgtg gattgagcct acaagcaatc aagttagtct
     2101 ttgactattt agaaaaatca gtaaaaacac ctgatatgga atcacgtgaa aaaatgcaca
     2161 acgcttctac aatggctggt atggcgtttg ctaacgcatt cctaggtatt tgtcactcag
     2221 tcgcacataa aatcggcggg gaatacggga tccctcatgg acggacaaat gcgattcttt
     2281 taccgcatat tatccgctat aatgcaaaag atccacaaaa acatgcgatg ttccctaaat
     2341 atgactattt ccgtgcagat acagattacg cagatatcgc aaaattctta ggtctgaaag
     2401 gcgaaacaac agaggaatta gtcgaagctt tagcaacggc tgtttatgaa ttaggaaaat
     2461 ctgtcggcat caacatgagt ctaaaagctc aaggagtcac acaagaaaca ctagatacaa
     2521 ccgtagaccg tatggctgaa ttagcttacg aagaccaatg tacgacagct aatccgaaag
     2581 aaccattgat ctctgaattg aaacagatca tcattgatgc ttacaacgga taagcaaaag
     2641 aaagcgtaga aaaaagataa gaaaatagat gaaaaagaac ttggaaaacg ttgtttctcc
     2701 aagttctttt tttaatttcc aagtaactga aagttacttt tgttatttaa catttaggtc
     2761 aattttagac agtttttgtt caaaaagcga tatttatagt ggacggtatt actgctatat
     2821 taaggatata aaatgaaagc gtttaaaaag gtggcgtaaa gatgattatt aaagaagaga
     2881 tttttgtacc taaagaatta gtgaaagaaa aaattgacct gctcgttgaa aacctgacaa
     2941 cgatcaaaga cgataatggt gaatttttgt tggactttga tggactgaaa gtagatgaca
     3001 aaagctggac agtgtggaat tggccacaag gtgtcggtct atatggtatt tataaaaatt
     3061 accagatgac aaaaaatcct cgcgcttatc aagtggtcaa tgaatggttt gaggatcgta
     3121 tggaagaagg cgctccgccc aaaaacgtca atacaatggc accgctattg actatggctt
     3181 acttgtatga agacacgaaa gattcacgct atttgcctta tttagaacaa tgggcagaat
     3241 gggtcatgaa tgacatgcct cggacaaatg aagacgggtt acagcatgcc acatatggac
     3301 cggaaaataa gaatcagttg tgggacgata cattgatgat gacagtgctt cctttggcaa
     3361 aaatcgggaa actgttgaat cgcccagaat atttagaaga agctcgttac cagtttatga
     3421 tccatatcaa atacttgatg gataaacgaa caggattgtg gtatcacggc tggacgtttg
     3481 aaggaaatca taactatgcc gaagcatttt gggctcgtgg aaactgctgg ttgacgattg
     3541 ctattccaga gatcattgaa atcttagaat tatcgaaaga agatgcattg cgcaaattat
     3601 tgatcgaaac acttgaagca caagtgcgtg cattaaaaac ttatcagtct gaaagcggtt
     3661 tatggcatac gttgttggat gatccttctt cttacgtaga atcttctgca actgcaggat
     3721 ttgcttacgg tattttgaaa gcggtccata aacgttattt accacaagaa tataaagaag
     3781 tcgcttatcg tgctatccaa ggattgcttg aacaaatcga tgaaaaagga gaagttcaaa
     3841 acgtttcaat cgggacagga atgggggaca gtttagattt ttatcggaat atcggaatca
     3901 cagcaatgcc ttatggacag tcgttaacgg tgctttgttt gacagaattg ctcgtctctt
     3961 attgttaaaa gaaaggaaac ccatatgaaa aaaacatcac tgctgtttgc agcaagttcg
     4021 cttagcctag gtctgctagg tctaagcggc tgcggaaata attctagtgt ggcaactgtc
     4081 gcagatgcag atgtaaatga gatagttacc ttgcgctttg cttatgcaag caacagccag
     4141 ccagtaattg atgcaatgaa tgaatttggg cgtttagtaa aagaaaaaac agatggttcc
     4201 gtacagatcc agtatttccc agatggacaa ctgggtggag aacgtgaact gatcgaattg
     4261 acacagtcag gagcagtaga tttcacaaaa gtaagtgcct cagcgttgga aagtttctct
     4321 aaagattatt cgattttttc agttccttat ctattcaatg atgaagaaca tttctttaag
     4381 gtgatggata atgaagaaat aatggagcca atctaccaat cgaccaaaaa tttaggattt
     4441 accggattga cctattatga ttctggtcag cgcagctttt atatggtaga cggtccgatc
     4501 catacgccgg aagatttgaa gggaaagaag atccgtgtga tgcaaagcga aaccgctatc
     4561 aaaatggtag agcttttagg cggttcgccc gtacctatgg gaagtgatga agtgtacacg
     4621 tctcttcaat ccaatttgat caacggatca gaaaacaatg aatttgtctt gtatacagct
     4681 ggacatggtg gtgtggctaa atactattcc tatgatgagc atacacgtgt gccagatatc
     4741 atcatcatga atgatgccat caaagaacag ctaactgatg agcaggaaaa agccattgaa
     4801 gaagcagcga aagaatcaac ggtttttgaa attgaagctt ttgcaaaagc aattgaagaa
     4861 gaaaaagctt tagcacaaga agaacatgga gtccaattca atgatgtaga taatacaccg
     4921 tttcgagagg cagttgcccc acttcatgat atattcaaaa acgatcctac ctacaaagac
     4981 ctttatcaaa agatccaaga gcaaggagcg tagctgtgat gaaaatgatt ttaaacaagg
     5041 tattagagat cctgggagct gttttgcttg ttgggatggt cgctgttgtt ttatggcaag
     5101 tattttccag aacggtttta ggaaatccaa atacggtcac ggaagagctt gttcgattcg
     5161 gtcttgtctg gtttgccatg ttgtcttccg cgtatgttgt gggacaaaaa gcacatttag
     5221 ccgtaacggt tttaagtgaa aaattaactg gcaaaaaaag taaaatttta gaagttgttg
     5281 ttcaaagttt atttctggta tttgctgcga tgatcatggt gtatggcgga tggaatgctg
     5341 tcacattgac aatggggcag atctcgcctt ctttaagtat tcctatggga tatgtttatc
     5401 tgtcagtacc tgtatcgggg gtactcatca ttatctatag cctgatcaat ctaatcgata
     5461 cattaagcaa caagccagca attcaagaaa aaatataaaa atggaggaat aaaatggcaa
     5521 tagaagccgg attagtgtta ttttttgtat ttgttgtgtt gcttgtatta gggatgccga
     5581 ttgctataag tattgcattc tcatcgatga tgactttatt gttagttata ccgtttgatg
     5641 tttctgcttt tagttcagct caaaaaatgg tgggaagtat caatagtttt tcgctgatcg
     5701 ctattccgtt tttcgttctc tcgggcatta tcatgaataa tggagggata gctaagaaac
     5761 tagtggattt tgcgatgttg ttcgtcgggc gcgtgccggg ggctttggct catacgaatg
     5821 tgttagggaa tgctttattt ggttccatct ctagctcggc cattgccgct tctaccgcga
     5881 ttggcggagt gttgatccct cagcaagtgg aagaaggata tgaccggaag tttgcgacag
     5941 cggtcaatat cgcgtcagct ccgacaggta tggtcattcc tccaagtact gcttttatca
     6001 tgtattcact tgttgctggt ggtgcttcga tctctgcttt gtttatggga ggttatctcg
     6061 taggcgcttt gtgggcgcta ggaatcatgc tagtagcatt catcgttgct aaaaagaata
     6121 aataccctgt tgtcgaaaaa ggacagatgg ctcatgctgg aaaaataata aaagaggcga
     6181 ttcctagcct tctattgatt gtcatcatta tcggtggtat cttgacgggg atatttacag
     6241 cagtagaagc ttcagcgata gctgtcattt actccctgtt gattgctatg ttttactata
     6301 aaacggtaaa actaaaagat atacctaata tgttgtttca atcagtagca atgtcaggga
     6361 cgatcatgtt cttattggct acttcttcca tgatgtcttt cgccatggcg tttaccggta
     6421 ttcctcaggc aattagttcg ttgattatgg gcgtaacgga taataaattt attattctgt
     6481 tattagtcaa tcttgtgtta ttactggtgg gtatgtttat ggatgtggcg cctgctatct
     6541 tgatttttac accaatattt ttaccaatcg tcacaagtgt aggggttgat cctgtacatt
     6601 acgggttgtt ttcaatcatg aatctgtgtg taggctccat cacgccgcca gtaggtacag
     6661 gactatatgt cggtgcaagt gtaggaggcg taaaagcaga ggcaatgctg aaaccgcttc
     6721 ttccttttta tggggttatc ttagtcgtct tgtttttgat tacttacttc ccgcaaatcg
     6781 tcatgtggct acccaatatg ctgagttagg agaatagtta tgttgaacat tacaattaga
     6841 ggacatgatc tttccgaagt ccaaacgata gaagatcttg cagaaaaaac aaaagaacaa
     6901 gggattcata cactgcagct cgccttaggt ctttcgtttc ctgaaatacc ttctggcgca
     6961 aatgagatca attctgggat gggaaattat gtcaaacgag ttttagaaaa gcaagaagtg
     7021 accgtaggaa ttttaagttg ctatatcaat atgattcatc cagatttaac gatacgacaa
     7081 gagttgctga caaagttcga gcagtatctt cgctatgctt cttcctttgg tgcgtcgatg
     7141 gttgcttcgg aaactggatg tgttttgccg gaaatccaat atacggaaga aaatttcaca
     7201 gatgaagcat ttgctgaagc tgtgtccgtt atccgtcgct tggtaaaagc tggagaaaaa
     7261 taccaaatga tggtggggat agaaccaggt ttgaatcatc cggtgtattc tttagcaagg
     7321 gtagagcagc tgatccaagc agtagattcg gactatctag gaatcatttt agatccgacc
     7381 aatttgatca caagtagtga ttatcaagaa caagtccaat tggtagaaga agcttttgaa
     7441 cgttttggtg aaaagatatg tgcggttcat ttgaaagatt ttcgtgtcga acaggaaaaa
     7501 atcgtgccgg taaatttggg agacggtgtg atcgagtaca caaaaatcaa agaaatcatc
     7561 atgaagaatc gtccgtacct gtatgtggtt cttgaagaaa caaaagatga tgggattcgt
     7621 tatggaagaa gtcttcttga ataatgtaaa gaagacgttg gttaactaat atttagaatg
     7681 gagggggcgg ggctagaaga tgccacgtct cttctttttt ataagagtat ataaaagcag
     7741 ctctttttga ttacaaaaaa cgtggtataa taaaattgtg cataagtgaa caaaaggagg
     7801 tgcggcacat gctccaaaag aaaatcagcg gtgaacaagt caatacgatg gtttctgatc
     7861 agtatgaaat ctatcatgtc aaagatgtcg tcagccaaaa taaaacgatc tatcatcatc
     7921 atgatttcta tgagatccat gctacattaa agggagaagc gactttttat ttgaacggac
     7981 gacaatttac gatcaaagca ggaagtgtgc tgctcatcca ttccaatgat ttgcatcgta
     8041 tcgtccgcca atcttcagat gtattcgagc gtgtctatat ctttgtcacc ccttcttttc
     8101 tagaaagtcg ttccacgcca tggtctaatc tatcggcttg ttttcaacca atgggagaga
     8161 agaggagtcg tgtattgcaa atagaacagg aagtattgaa gcaaaaatta tcatttatcg
     8221 accatcctcc tgataaaaaa atttacggtg aagacataaa atatgaacaa gctctggtag
     8281 aatacttgat ttttctcaat caagttgtac aaaaagaaga gagtgcgcaa gaacagaatg
     8341 ctgtagttcc taatgagcgt gtggaacaaa tgttacaata tatctcaaaa aatttatctc
     8401 atccgctttc tttagaggaa atggaaaagc agttttttgt cagcaaatac catatcacac
     8461 gagaatttaa aaagtacact ggatttacgt ttcatcagta tgtaatgaag aaaaagctga
     8521 tctatgccaa gcacttgttg cgagaatacc gcagctctag tgctgtatat agtaaaagtg
     8581 gtttttcttc ttatccgcat tttctgaaag cattcaagag agagttcggc ataacgccta
     8641 aagaattttt gaaacgtgat acacagaaac agttggttca ttatgaacat tttgaagatg
     8701 aacaatgaga atgatcacta aaaaataacc gcagtagctg ctgttgttta catagaagca
     8761 gaaactgcgg ttattttatt tttatctata tatttcaaaa tattttgaaa aaatgacgta
     8821 catattatat gaatcagctg aatttacgaa agtctctcgg cgatagtcct gtttttgctt
     8881 tgaacaggcg gctaaagtaa gcaaaattct caatccctat ttcttcggaa atcattcgaa
     8941 ccgtaaattc tgtataccga agaaggtctt tagcgtaaga aagttttttg ctgatcaaat
     9001 aatcgattgg tggagaaccg ataaatttgg aaaaatcttt gctcagctga tatttattca
     9061 ataagaattg ttgttctaat tgatcaagtg taatcgtttc tttgaaatgt tcgtctaagt
     9121 attgcttcag tttgtaaacg taggcgggaa tatcctcttc ttcgaaatct agctgatact
     9181 tttgcaaaat cagttcattc agcaactcgt ggatagctac agaggactgg aaatcggtac
     9241 gggcattcgt gccttgttgc atgtggatca attctgtgat caaatggtgg atcttgtttt
     9301 ctgatggatc tcctgttgaa tggaaggtgt tatggccgtc ttttgtgaac tcctgataaa
     9361 atgattggac gttctgacca ttcaaatgga tccaatccat ttcccatggt tcttcgctga
     9421 tcgtttgata acgctgatat tcttggcagt caataaaaaa taagtctcca gcttttagct
     9481 gttgctgatt atcattatat gtaagcgaac ctttgccaga caaagtaaac tttatcaagt
     9541 aagaaggtaa atgtgctcgt tcagtatagt aagggattgg tgctttgaag taaccgattt
     9601 cttggatata aaaaaataaa ttcctgcttc tttgtgtagg cgtcaagatc actctttttg
     9661 agtcttccga ccatgagtgg ttggcttttt cccagtaatc catgtaaaca ctcccaactt
     9721 gtcaagataa tgcaattata taccaaaata gtgtgaagca aaatataaga ttctgtatta
     9781 tgatagcatt gtcaataaat gataacgctt tattaataaa gtgctaatca acaataaagt
     9841 aaaagaggtg gagaaatgaa tccaacattt gttgccatcg atatcggtgc atcaagcgga
     9901 cgactaatga aaagtacgag ggatgcaaaa ggttctttga tcttggaaga agtacaccgg
     9961 ttcaaaaacg gctttcggaa caaagacggt cacgatcgct ggaagatcga ttatcttatc
    10021 aaagagattt tgattggatt tgaaaaatta aagcagacag ggattgatcg cctttttgcg
    10081 gggatcgata catgggcagt cgattactgt ctgattgatg aacaagggga tcggataaat
    10141 gatccgattg cttatcggga caagcgtacc aatggagcag tagaacagtt ttctgaaatc
    10201 tattctctag ataagttgta tgagcagaca gggattcaga tccagccttt caataccttg
    10261 ttccaattgt ttgctgaaga aaaagaaaat ttggcaaaag cacataaatt gttactgata
    10321 cctgattatt tagggtatgt ctttactggt aacatggtga cggagaaaac taatgcatct
    10381 actatgcagc tgctgaatgc agggacaaaa gaatgggaaa tagaacttct tgaaaaaatc
    10441 ggtgtctcga aggaattatt tccaccattg acagagccgg gaacgatact aggagatctg
    10501 caaaaagaac aattttcaaa atatgatttg ccagatgtga cctttatcac agtagcaagt
    10561 catgatacgg cgtcagctgt attaggaacg ccaggtcaag gagaacgttg gggttatatc
    10621 agcagtggga catggtcgct tttagggatt gaaacaaaga tcgccaatgt ttctcgcaat
    10681 gctttttctg aaaattatac gaatgaatgg ggtgcccata acacggtgcg ttttttgaaa
    10741 aacatcatgg ggatgtggtt gatccaggaa gttgcccgaa tgcaagagta cgagtacagt
    10801 tatgcggaat tggcagagct tgctgcaaaa gaaaaaccgc tgcagcaagt gatggaaatc
    10861 aatgaccctc gatttttgaa tcccccaaat atgatagaag agattcagca atactgtttt
    10921 gaaacagagc agccagtccc tgtctcatcg ggagctatcg ctcgttgtgt gtatgataat
    10981 cttgctcttt gttacgcaca agagctgatc aaagtagaac acttaactgg aacgaaattg
    11041 gaaaagctgc acatcgtagg gggcggatcg aataatcgtc tactgaatca attgacagca
    11101 gattatgccg gaatcattgt agaagcagga cctagtgaag ccacagcaat cgggaatgtt
    11161 gccatgcaaa tgctcagtac aggtcagttt tcgaatatag aacaagcaag aaatgtaatc
    11221 aaacagtcgt ttccatgtga aactttttac ccagatgaaa ataagcaaaa cacgatggaa
    11281 tggtacgtga ataaaatcaa aggagtaatc gtatgaacac gattgaaaga aattacgaac
    11341 aagcaaaaga aaaatatgca actatcggtg tagatacaga tgctgtacta gaaaagatac
    11401 aggacatcaa aatttctatg cattgctggc aaggagatga tgtcaaaggt ttcttgacac
    11461 cggatggcga attgaccggt ggaatcatgg cgacagggaa ttttccagga gccgcacgaa
    11521 cacctgaaga gcttagacaa gatctggaga aggcttattc gttgataccg ggcaaacaca
    11581 aattgaacct tcatgctatc tatttggata cagaagaatc tgtcgatcta aatgaaattg
    11641 agccgaaaca ttttgaaaaa tgggtagagt gggcaaaaaa agaagaaatc ggtcttgact
    11701 tcaatccgac tttcttttcg catccaatga tgaaagacgg ctttacattg gctcatccag
    11761 ataaagaagt tcgtgaatac tggatcgaac acgggaaaag aagccgcaaa atcgcggagt
    11821 actttgggaa agaaactggg caaacaagta tcaataactt ttgggtacct gatgggatga
    11881 aagataatcc gattgatcgt tttaccccac gggaacgttt aatggaatca ctcgatgaaa
    11941 tttttacaga agagttagat gaacggtatg tacaagatgc agtagaaagc aaactatttg
    12001 gtttaggcgc tgaagcttat acagtcggtt cccatgaatt ttatatgggt tacgggttga
    12061 ctcgtgacaa acttgtttgt ctagatgctg gacattttca tccaacagaa gtgatttcca
    12121 ataaattatc ttcattagct ttattcagca aaggaatcat gttgcatgtt tcccgtccag
    12181 tgcgttggga ttcagaccat gtggttttga tggatgatga attgcaggaa atcgctaaag
    12241 aattagtccg taacgaattg ttggaaaaaa caaatatcgg tctggatttc tttgatgcaa
    12301 cgatcaaccg tatcgctgct tgggtcatcg gtacgagaaa tacacaaaaa gcactgctga
    12361 aagctatgct ggaaccagtt gagcgattga aagaaatgga gctggctttt gactttactt
    12421 caagaatggc ttatacggaa gaattgaaag atttcccgta tgccgatgta tggaattatt
    12481 tctgttacaa aaatcaagtt ccagttggtt tggattggct ggaagaagtc caggaatatc
    12541 aaaaagacgt gttggaatta agaaaatagg agtgtggcta tattgaaaaa aatagatatt
    12601 ttacaagcgc cttatgtgaa agaaatgatc gaaacgacgt cgaatcttta tcgcttggga
    12661 tgggatgaaa gaaatggcgg gaatatttct tatttactaa aagaagaaga gatcacaccg
    12721 ttcttggatc ctgaaaaagt gatccgccgc atctcgatga tttttgatgc cagccgttta
    12781 gcaggatgct attttattgt aactggttca ggaagatatt ttaaaaatgt agcgagcgaa
    12841 cctgccgaga atcttggaat cgttcgagtt gctgaagatg gcaaaacact ggaacttttg
    12901 tgggggctgg aaaacgaatg ccttcctaca agcgagttgc caagtcattt catgagtcat
    12961 atcgcccgtt tagaagtaga cccagataat cggatcgtta tgcattgcca tgctagtcat
    13021 ctattagcga tgagttttac gcatgaatta gacgaacgtt cctttagtcg tacgctatgg
    13081 caaatgtgta cggaatgctt agttgttttt ccagaaggaa tttccatcat tccgtggatg
    13141 gttccgggaa caaatgagat tggggaagca acagctgaaa aaatgaaaga aactcgattg
    13201 gttttatggc cacaacatgg aatctacggg tcaggaaaag acatggatga agtctttggt
    13261 ttgatcgaga cagcagaaaa ggcagcagaa gtctatacgt acgtcaaagc gcaaggacca
    13321 atcttgcaaa caatcacgga cgaaaacctg tggcatttag cagatgcgtt tggtgtcact
    13381 ccaaaagcag gttatttgga ggaagttcat acgaaagcag gtgtctgaca tggtgaaaaa
    13441 agctttttgc atgaaagttt acccagaaaa acaagaagaa tacaaaaaaa gacatgatga
    13501 actttggcca gaaatgcgta cagcacttcg tgaacacggg gtcatcgact attcgatcta
    13561 tcttgatccg agtacaagtt tgttatttgg ttacttagtg atcgaagatg aaaagttatg
    13621 ggaaaaaatg gcaaatacat ctatcaatca aaaatggtgg aagtacatgg aagatatcat
    13681 ggagacaaat ccagatgcct ctccagtcag ttgggaattg atgccagtct ttgaactgta
    13741 gcaacaagca actgggcaac cggttgcttg gggttctttc gtttttattg tgaaaaataa
    13801 tacaaattag gaggaataga aaatgagtaa tcgaatgatt ttaaatgaaa catcgtattt
    13861 tggaaaagga gcgattgagt cgatcgtccc tgaatttcag cagcgaggat tcggcaaagc
    13921 agctgtcatt actgacaaag gattgatcga gcacggtata gcaacaaaag taacagaact
    13981 tctagataaa gcagcaatcg cttatgcttt atacgacggg atcgtaccta atccaacgat
    14041 ccaaaatgta aaagatggag tggcttttgt taaagaggca gaggcagact gtttgatcgc
    14101 aatcggtgga ggttcgccaa tcgatacggc aaaagccatt gggattattt tgacgaatcc
    14161 agagttttca gacgtcatta gtttagaagg tgttgctgat acgaaaaatc catgtttacc
    14221 tatattagct ataccaacga cttctggaac agcagcagaa gtaacgatca actacgtcat
    14281 cacagatgaa gtaaatcacc gaaaatttgt ttgtgttgat cctcatgata tcccaatcgt
    14341 cgcgttcatc gacagcgata tgatgatggg aatgccgaaa aaattggctg catcaacagg
    14401 tatggatgct atgacgcatg ctattgaagg gtttatcaca aaaggcgctt gggaaatgac
    14461 tgatatgctg catttaaaag caatcgaaat catcggccat tctttggaag cttctgtaga
    14521 tggcgatcaa aatgggcgag aaaaaatggc attaggacag tatattgcgg gaatgggctt
    14581 ctcaaatgtc ggtttaggac tggtacacgg gatggctcac ccgttaagtg catggtacaa
    14641 cattcctcat ggcgtagcgt gtgcagcact tttgccaact gtcatgaaat ataacaaaga
    14701 atatactgga gaaaagtacc gtgagatcgc tcttgttcta gggattaaag gagcagctga
    14761 aatgtcttta gaagatgtaa gagaagcggc ttgtggtgag atcgatcggt tgagcaaagc
    14821 ggttggaatc ccagaaacca tttctgaatt aggtgtaaaa gaagcagata ttccagcaat
    14881 tgcagaagat gctttgcgag atgtatgcac accaggaaat ccaagagaaa cgacagtaga
    14941 agaaatcatt gctttatatc aaagtttgat gtaaaaacga agcggatctt caacattaaa
    15001 ttgcctgtaa agagaaatgg tagtttatat ctggatatct cttttaaatt gatggtattt
    15061 ccgctataat ttttcttata aagaaatagg agaatattat atggaaaata aaaagcctta
    15121 tggaactgta ttgatcaaag cctctaaaat actagactat ttagcggaaa accaagatgt
    15181 ctctttgcag acgatcgcaa agggtgtggg aatgacctct tctacagtct tgaaaatact
    15241 agatactttg ttgatgatcg gctacgtaaa taaaaattca gagaaaaact atcgtttagg
    15301 tgcaaagctt attcgctacg cgaataaaaa cattgaacaa atcgatttgg tagagttgac
    15361 tttaccgttt ttagaacagc tgcagcaaaa gatcgatgag actatccact taggggtatt
    15421 ggacaacaat gagatcttgt acgtgaacaa actagatcca aaacatcaaa cgatccgcat
    15481 gtcttcaaaa atcggaatca cccgaccatt atacaattct gcgatgggca aagccgtatt
    15541 agcagaattc agtgaagagc agtacactga ttatcttgaa aagcatccgt tgatccctta
    15601 cacagaatat acgatcacca atgcattacg gttgaaaaag gaaatcaaaa cggtaaaaga
    15661 aacccacatc gcatttgacg atgaagaaat cgaacgtgat attttttgta taggagcctc
    15721 aatcgtgaaa aacgaacaaa tcattggtgc atttagtgta agtatgccga aatatcgttt
    15781 aacagatgag acaaaagaac aaataatcag tgccctcaag caaacaaaaa gcgaaatcga
    15841 gcaaagaatt caaaaataat gaaaaaagcg tttgcaattt ttcttttctg ccgtataata
    15901 tgggtataga tttccaagtt ataaaataaa atttctaaat aggaaatagg tggagaagat
    15961 gaaaaaaatt gatattttat ctcgattgaa aaacgccgga gtgattgcgg tggtacgcgg
    16021 aaaaagcaaa gaagaagctt tgaatgcttg ccacgcaatc atcaaaggtg gtctaactgg
    16081 tattgagttg acttttacag tccctcaagc agatcaagta atcaaagaac ttttgtcatt
    16141 ctacaaagac caaccagaaa tagtgattgg cgcaggcaca gtattagacg ctgtcacagc
    16201 tcgcttggct atcttagctg gcgcagagta tattgttagc ccttcctttg atcaagaaac
    16261 ggcagagatg tgcaatctgt atcaaattcc ttacttacca ggatgtatga ctattaccga
    16321 gatcaaaaca gcgctgaaaa gcggggtaga tatcgtcaaa ctatttcctg gaagcgctta
    16381 tggaccaagt atcatttctg ccttcaaggc gccgatgcct caagtcaata tcatgccaac
    16441 tggcggtgtg agtctggaca atatgaaaga gtggttcgat gctggtgtcg taacagtcgg
    16501 agtaggtggg aaccttttag cacccgcagc tacaggagat tttgacaaag taacggaagt
    16561 cgcgcaacag tatgcagcaa aaatgaaaga aatcaagagg tagctgctta tgggaaaagt
    16621 agtgacactc ggagaaatca tgttgcgatt gtccacagag cagggaaccc gtatcgattc
    16681 aagtgaacga ttcgctgccc attatggcgg aggggaagca aacgtagcaa tttctttagc
    16741 taattacgga catgaagcga tttttgctac aaaagtacct gataacgcat tgggaaaagc
    16801 agtcaaaaag cacttgcaat gttatggagt agatacgaaa caggtattat ctggtggatc
    16861 aagactaggt acttattata tggaaactgg tagtggcgaa cgcgccgcct cagtgatcta
    16921 tgatcgtgcc ggatcaagtt ttgctgaaat ggatcatttg gaatggtcgc tagaggagtt
    16981 attccaagga atagatatat ttcatgtttc aggaatcacc ccagctttgt ctaaaaaatg
    17041 gcaaaaaatg acgaaacagg tgatagaagc tgcaaaaaaa gctggctgcc tgatcagctt
    17101 cgatatcaac tatcgtggaa aattatggac acagcaagaa gccagcgaag taatccatca
    17161 gcttttacct ttagtagata tctgctcagc tggaaaaatg gatgctcttt atttgttagg
    17221 tatcgagaaa gcgccagaag cagaagaaca acctctaatt tattattatc aaaaaatgca
    17281 ggaaaagttc ccgaatattc aggtgtttta ttcgaccaag cgtaccgttc attcagcaag
    17341 tgaaaatgaa ttgaagggga cattgtggat gaaccatgaa tatgtggaat cccaagtcca
    17401 tagaatcacc ccaatcgtgg atcgagtagg tggcggagat gcttttgcag gtggcgtgct
    17461 ccatgggatt ttatccaata tgtctccgca agaaatcatt gattttgcta cggcagcttc
    17521 tgccttgaag catacgatcc atggggactg caaccaattt agtcaagaag aagtcgcaca
    17581 atttttagca tgcggctctg gaaaaatcat tcgatagaag gagtagaaga aaatgcaaga
    17641 aatggaaaca cgttatacac acagtccaga agatatccgt cattattcaa cggaacaatt
    17701 gagaaaagaa tttttagtag aaaaggtatt tgaaccaggg aaaatcagtt tgacttatac
    17761 gcacaacgat cgaatgatct ttggtggagt gacacctact gaaaaagaat tagaaatcac
    17821 attagacaaa gaactaggtg ttgattactt cttagagcgt cgtgaactag gtgtgatcaa
    17881 tatcggtgga ccaggattca tcgagatcga tgggcaaaaa gaagaaatga aaaaacaaga
    17941 cggatactat atcggaaaag aaacacgaca tgttgtattt tcttctcaag atgctgaaaa
    18001 cccagctaaa ttctatatta gttctgttcc agctcatcat aaatatccaa atgtaaaaat
    18061 cagtatcgac caagtaaaac caatggagac tggtgaaggc ctgacactga atgaacgtaa
    18121 aatctaccaa tacatccatc caaatgtatg cgaaagctgt caattacaaa tgggttatac
    18181 gattttagaa ccaggaagcg cttggaatac gatgccttgt catacacatg aacgtcgtat
    18241 ggaagcttat gtctactttg attatgccaa tgaagataca cgtgtgttcc acatgatggg
    18301 caaaccagat gaaacaaaac atttagttgt agacaatgaa caagccatta tttcgccaag
    18361 ctggtcgatc cattcaggtg taggtacaag caattactca ttcatctggg caatgtgcgg
    18421 agaaaatatc acctatacag acatggatat ggtgcaaatg gatcaattaa aataagcata
    18481 agggagagaa aatgatggaa tttagtatgg atatgtttcg tttagatgga aaagtagcat
    18541 tagtcaccgg tgctgtctat ggtattggat ttgagattgc acgctcttta gctacagcag
    18601 gagcaaaaat cgtatttaat aacttgaatc aagaatcagt tgatgaaggt atagcgcatt
    18661 ataaagaagc aggcatcgat gcaaaaggtt atgtctgcga tgtgaccgat gaagaagcgg
    18721 ttcaagcgat ggttcaacag atcaaagaag atgtaggttc agttgatatt ctagtcaaca
    18781 atgcagggat catcaaacgg acaccgatga tcgaaatgga tgcggcagac ttccgccaag
    18841 taatcgacgt ggatttaaat gccccattca tcgtttcaaa agcagttatt ccggatatga
    18901 tcgaaaaagg cggcggtaaa atcatcaata tctgctccat gatgagtgaa ttaggacgcg
    18961 aaacggtcag tgcttatgct gcggcaaaag gcggattaaa aatgctgacg aaaaacatcg
    19021 cttctgaata cggtcaatac aatatccaat gtaatggaat tggaccaggt tatattgcta
    19081 caccgcaaac tgctccatta cgcgaaacac aagaaaacgg tgaacgtcat ccattcgatc
    19141 aatttatcgt tggacgtacg ccagcagcac gctggggcga gccaatcgat ttggctggac
    19201 catctgtctt cttggcttct agcgcatctg atttcgttaa cggccatgtc ttgtatgtgg
    19261 acggaggcat acttgcctat atcggaaaac aaccttaaaa gagctttagt acactgttta
    19321 gtggagaggt tgtgaaatca gcggattgaa cgaataccga aggacagctg attaaacatc
    19381 atttattcga aaaaagaggc tgggacagaa gcatttaact ccaagaaata agaaggaatt
    19441 cacgaaaatt gcttttcaaa tttttgtgaa tttcagctta tttccgaagg agttgctttt
    19501 acttccgccg tttgtacgtg tttagagcgt gagacaaaag tgttctttac ttttgtccca
    19561 cgctcttttc tgtgcgtctt ccatacttca ctaagtcgat ccctcttgct tcgcaccaat
    19621 ccttcactgg tccggaaaag atcagagatt gttggtgtag ggccgcggta ttcgttgcgc
    19681 cgaccatagt ataaagcaga cgaagctctt cttgccattg cttcatcagt ataatagttt
    19741 cttctacgcc gtgattcatc agatgcgtca gtacggttcc tgaagtaccc acggcatttg
    19801 cgccgagaca aagggcttta aatatgtcat aggcattgcg gatacctccg gaggctagga
    19861 tttccataga agtgtctgct tcatttgctt caagcaatga agagactgtc gattgccccc
    19921 agtcagctaa ataactcagt tcccgcttgg agcgacgggc gttttcgatc tgggtgaagc
    19981 ttgttccgct tcgaccgctg atatcaactg tatgaactcc taaagcagct agatcattga
    20041 gcgtttctct tgtcatgcca aaaccgactt cttttacgat gagggggacg tcaatggctg
    20101 tttgagtttc ttgaataagt actttccaat tggtaaaatc acggtctccc tcaggcataa
    20161 ccaactcttg aggtgcattc aaatgaatct gtaaggcatc tgcgtgaaac aatcggatag
    20221 cttctttggc tctttcgaca gaagtccctg caccgatgtt ggcaatgatt ttcccgtgag
    20281 gatattcttg tcgcataatc gtataagtat cggctaaaga agggactttc aaggcagcgc
    20341 tgactgaacc agtggcaatc atcaaatctg cttctcttgc gacgattgca agatcttggt
    20401 tgattttttt tgttttttcg cttccgccag tcatcgcatt gatataaaat gggctgctta
    20461 gtgtaaaccc aactgcctgt gtacttagat cgacatcaga aactgctatt tgcggcaaag
    20521 ggttatggat gatccgtacg aagtcaaatt cgtttttttg tttatcatga aaggctttag
    20581 ctagtgaaac atgttcgtct tttcgattca tcggttttcc tttctttgat cgctatagac
    20641 atgtaacggc agtggagtga tttctgcttt ttcccatgca ctcattaaag gaagaatgcc
    20701 agatttctgg tcaacaatta cgattccgca atcgccccca cctgcaccag aagattttgc
    20761 ggctccttca tactgttcag ctaaattaca caatttgttc aaagcaggcg tttcgatgac
    20821 gaccccagtg attgcagata aatcatgcag taattgtcgg ttttttcgaa tcatctgttg
    20881 gatcaacgtt acattatttt ctttaaaccc tttgatcatt tcgttgacac attctgtact
    20941 attttttaag aaaagctgat aagccaccat tttatcttct ctcgaacggt gaacttgatc
    21001 gaccaaatca gaagtagagg cagggctacc cgtccaacca atcaataaac gtaaatcttc
    21061 aggagcaatc aatggctcaa tggatagacc tggccaatcc agggcaagta actcactgat
    21121 agaatgctga gtttcttgtt cttggagcca aggatggtcg aaggttgaga aagcgatcca
    21181 gccaccataa cagctagcag cgatgtcgcc gcaggaacca ttatcttgaa ctgctaaatt
    21241 ggctagtgct gcaatcttga aaatctccaa ctgagataaa ttcaacgcgt aaaaaacatt
    21301 caaggctttg accgttgcaa cggtcacggc accgctagaa cccaatccat atttccggcc
    21361 atttgaactg tctaactcac ttgttacttt cagatcataa aaggataaaa gaatgttttt
    21421 ttcttgtgca tacttttcag tcaagcgaat agcagcaagg atataatgaa aaggattttc
    21481 ccgaatatct aaaactaatt ctccgttgcg tcttgtccaa cgtacaggca tcccactata
    21541 ttgtgcagat tggatacttc cgacttttcg tgcagattct acagtgactg tcacgaattg
    21601 atcgactgca gcgataactg ctggatggcc tgtttcaaca actgcatatt ctccggcaat
    21661 atagagtttg cctggtgcag atacttcaat cataaaaatc tccctttatt caataatcgc
    21721 aattcctgga ccagcatgtg cagtaattac ttgttctttg ctaaataatt tggtaaatgt
    21781 ttcttgtacc tcagataaat ggctgttttc cactaaaact ttgacattag ggccagcatc
    21841 catcgtaaag tagcatggaa tgccttgctt tctcaattgt cgcaccgcat ccatcgcttt
    21901 taagctgtca ggagaccagt aagtgaatgg aggctgggca gctaaagtcg ttccatgcat
    21961 ttttagtccg tttctttcca tcgtttctcc gagaagttgg aaatcttttg ttttgattgc
    22021 ttgtttcaat tgatatagat ccccttcaac ggaatctaac cagccttgat aaaaactgga
    22081 tgtttcgact gtccgacgca tcccatttct gctggacact tcttttttct ggtcgttgat
    22141 caaaacgaaa accattgcta aatcgtcttc gaaagaatcg gaagggactg gcttagcgta
    22201 agaacttaag tcgtcatggc ctttttccca ttcgacgaaa ccaccgaaaa tacttcggca
    22261 agctgaacca gacccgcgtc gagcaaatct tgaaagagag agatcatcta atccaagctt
    22321 aagagcagta ttgcaagcgc ctgctaaagc agctagcccg ctggcagagg aggctaatcc
    22381 agctgcggta ggaacgaaat tctgactgat tactgaagct tttagtgaga ggccggcttc
    22441 tttacgaaaa aggtcaagaa actgactgac tttttttgtt gctttttcgt cttgcaaggt
    22501 gccatctaga taaaattcat ctaccatata gctatcagaa aagatgactt ctgtctctgt
    22561 ataaaatgca tccaatgtta acgaaaggct gttgttcatt ggaaggatga gttcttcatt
    22621 tttcttaccc caatatttga ttagagcaat gttggtatat gcgcgtgctt tgcctttaaa
    22681 cataggtatg tactcctaat ccttgtatcc aagtttcagc agcacccgca tcttcaagtg
    22741 cttgactgat ttcttgggct tttgtttttg tttgtgctaa tgcaatcata cagccaccgc
    22801 gtccaccgcc agttaatttg gcacccaatg ccccggtatc ttttgctgtt tggatcaata
    22861 gattaagaaa atcattgctg attgtcagct tttccagaag tgattgtgat tcatccattg
    22921 tctgtgccaa cgtttctggt gaattttcaa tgattgcttg ttttgcttgc ttcgtcaagt
    22981 atcctaattt ttggatcatt tgtccagttt catgaggctg ggtttcaaag aggtgagcga
    23041 catctttgac ggcttctctt gtttgtcctt tgattcctgt atcagcgaca atcaaaaaag
    23101 catcgatgtt caaagaaaag tagtcgaaag gatgcccttt tgtaaaataa atcggctgca
    23161 agctgctagt agcggctgca tcgattccac taggattacc atgggcgatt ttttccgaaa
    23221 gctggacatt ttctaatagt atttcacgag acaaaggaaa tgctaagtaa tcataaaaag
    23281 cacgagtgac tgctgtggcg actgcagcgc ttgatcccat tccacgttca gcaggaatcg
    23341 tgctttcaat ggtcagttgc aagttttttt ggatgtcatg ctgttttttt aagtgaatga
    23401 ataatttttt gatatttttt aatgcatgag gagcttcggc taaatttcct gaatagtagg
    23461 aagaaaccag ttgatcgtcc attgcatcca gctcttcaag gaatgcggtg acttttgttg
    23521 catagaaagg aaaggcaatc gctggttctc cataaacaac cgcgtgctcg cccatcaata
    23581 tgatctttcc gcttgattct ccttggccat agtttgccat aatctaactc cttctcacgt
    23641 aaaagtgatt tttaagcaaa aaataaagcg cccaaaacga gttgcgctgc ttcacgaatt
    23701 tttttgtcca ctaagggtct caaaaaacat tcctccttta ttttactaaa accatctcag
    23761 aagtaaaact aagaatacgt tttctaaaga aaaaacactt ttttcttaag aattttttga
    23821 ctttttttct tctttgacta gaaaaaaata caattgacac tactagatat tgggggtata
    23881 tttaaaaagg ttggagttaa acacaatatt tagtgatgaa gtgagctgga ggtaaatgag
    23941 cgtgatcgtt ttagcaggta caattggtgc cggaaaatca agtttaacag aaatgatggc
    24001 tgaacacttt gatagtcagg cattttatga atcgattgat gataatgaag tcttgccctt
    24061 attttatgca aaccctgaac agtatgcttt tttgctgcaa atttattttt tgaataaacg
    24121 ttttgcaagc atcaaacaag caatgaaaga tgacaataat gtattggacc gttcgattta
    24181 tgaagattca ctgcttttcc atctaaatgc agatctagga agagcaacag aaacagaagt
    24241 tcgtgtgtat gatgaactgc tggaaaacat gatggaagaa cttccctatg ctgcccataa
    24301 aaaacatccg gatttattag ttcatattcg tgtatctttt gatacgatgt tggagcgtat
    24361 cgaaaaacgt ggtcgttcgt atgaacaatt gtcctttgat ccaagtctat acgattatta
    24421 caaagaattg aacagacgtt acgatcaatg gtatgaagaa tacaaagaaa gtccaaaaat
    24481 ccaaatcgat ggagaccgct ataattttgt ggaagatcct caagcaaaag aagaagtctt
    24541 gaaaatgatc gaagaaaaat tagcagagat tcgccaaacc aaagtagcca tttgatttac
    24601 agttgctcaa ataaagggta aacctttatt tgagcgactt ttttctttat actggaaaca
    24661 aatgtcagga ggatagagta tgcgggaaaa acactatttt aatcaagacc gtaatttttg
    24721 gatcaatgta cagcaaaacg atgtgctagc tgttaaaaac ttaaaagaag aatatggcat
    24781 tagtgacgag atgctgactt attctctaga taaaaatgaa cgggcgcgcg tagagtacga
    24841 ttcttttgat gaagcgttac tgcttgtatc aaatgttccg caccagcaaa aagtcgataa
    24901 tcattatgaa actagtccta tcgcttttat tttaaaagaa gacggtttgt ttacatttac
    24961 cacgccgaat accgagtacg tgattcgact aattcgatcg cttttggaac gaatgccaga
    25021 catgagtgta tacagtttat tgtttcgtac attgtttttg atttctgatt ccttttttcc
    25081 tttaatcgag gaagtgaata gtgaacgtca gcggcttaat ctgaaattaa gagaaaaaac
    25141 aacgaacaag aatctgctgc aactttcaga tttagagatc ggtttggttt acttagttac
    25201 aggaacaaaa caaaatgtag tacttttaga acaaatcaag gcattggcta tttatcgcaa
    25261 gttgtcagaa aaggaaaaag aagagttgga cgatgcgctg atcgaagcac gacaagcagt
    25321 tgaaatgacg aacttagctt cgcagatttt agaccagctc tctggcactt ataataattt
    25381 gctgaataac aacttgaatg acacgatgaa atttttgacg gtctggtcgc tgatcttgac
    25441 cgttccaact attgtgacag gattcttcgg aatgaatctc cagttaccct ttacccattc
    25501 cgttttcgga tggggaatcg ccttgatcat cagtttggtc ttatctattt ggatgcttat
    25561 tgcactgtgg cggcggattc gttgatctag tctttgatct gcaaaccaag ggcttgggcg
    25621 atcacaagtg cttgctcttg gttgacgatt agtcccgcca aagaatcttg agataaagcg
    25681 attgctgtga agaaattagt cgtaaagtct aatcccttca gagaagttcg aaaccagttc
    25741 gaaccggtca actgattgtc agacaaaaaa aggtttttcc aagtgacctc ataaaattcg
    25801 ctgtcttcta attgacaatg atcgaaggag acagctttca agtttgtact actaaaggaa
    25861 gccatcgaag caatacaatc agtgaaagta cagtctcgaa gataactttc ggcaaaattc
    25921 gtacctgtta atttacattg atgaaacacg acttggtgga aactgccacc aatccactcc
    25981 agattggaaa aatcacattt ttcaaaaatg acattactgc attcaaaatg acgtaaaact
    26041 gttttttgca tcgtaagttt ttggatatga ctctctctta ataccatatt tttggcatcg
    26101 agatagcttt ggtcaccccc gttgatcaga agaccagaga agatctcctc atcttctaaa
    26161 taaaactctc cctttgtaag aagaggaaga gaaggtggaa taggttcgat ttttttcatg
    26221 tgggttcacc tcgtttttct ttagtatagc aaagaagcgg gaatcactgc tagaaagtct
    26281 gctaatctaa tcattttcag aaaaggaaga caaactgtat gaaaaacatt gacaaaaaga
    26341 ttagtttttg ctatactatg atggttgaga aataaaagca gaagcacccg cttctcgcct
    26401 tagttgataa tgtcactggg ctagatagtt ttcactggtt ctattaggtg aagtacgcgc
    26461 gggttctgta agagaactcg tttttttatt gccgtttatt cggtaagctt ttctttctct
    26521 cataatattt ggaggtgaat gaccatagca aaggatatga tggttaacga cggcattcgt
    26581 gcacgagagt tacgattgat cggttcagat ggtgagcaat taggagttaa gacaaaagca
    26641 gaagcattga atattgcaga acaagcaaac ttggatcttg tgttagttgc ccctggtgcg
    26701 aaaccaccag ttgcgcgaat catggactac ggtaaatacc gtttcgaaca acaaaagaaa
    26761 gaccgcgaag cgcgtaaaaa acaaaaagtg atcaatgtaa aagaagttcg cttaagtcct
    26821 acgatcgact tgaatgactt caatacaaaa cttcgtaatg cacgtaagtt cttggaaaag
    26881 ggcgataaag tgaaagcttc tatccgtttc aaaggccgtg ccattaccca taaagaaatt
    26941 ggtcaaaaag tcttgaatcg cttagctgaa gaaactgcgg atattgcaac agtggaacaa
    27001 aaagcgaaaa tggacggacg cagcatgttc ttgacgctgg caccgaaaaa cgacagtaag
    27061 taatttgaat gactaactgg ctgttggaca gccgatagtc ggataacgaa agattttgag
    27121 gaggaaatat agtcatgcca aaacaaaaaa cacaccgcgg atcagcaaaa cgtttcaaac
    27181 gtactggtaa aggcggattg aaacgcttcc gcgcgtttac aagtcaccgt ttccacggca
    27241 aaacaaaaaa acaacgccgt caattgcgta aagcaagcat ggtttctagt ggcgacttca
    27301 aacgtattcg ccaacaacta gcaaaaatga aataagaagt acaaataaca gaatctgaag
    27361 atttattttt attaggagga attatacatg gcacgtgtta aaggtggaac agtaactcgt
    27421 aaacgtcgta aaagagtgct aaaattagca aaaggttact acggttcaaa acacacttta
    27481 tttaaaacag caaaagaaca agtaatgaat tcatacaact acgcatatcg cgatcgtcgt
    27541 caaaagaaac gcgacttccg taaattgtgg attgctcgta tcaacgcagc agctcgtatg
    27601 aatggcttga gctactcaaa attaatgcac ggtttgaaag ttgctgaaat cgacatcaac
    27661 cgtaaaatgt tagctgactt ggctgttaac gatgcagcag catttactgc attggctgac
    27721 caagcaaaag aagctttggc taaataagct aaacaattat aaagaggaaa gaagataacg
    27781 aaaagttatg ttctttcctc tttttttatt tacaatcctc catcaaatga aacaggacaa
    27841 taacgtataa gtctaaaata gcataattaa ggttttttaa ttgaaaactg aacatttatg
    27901 gtcacccttt aatgaaagcg ctaactacat aagttagaat gagtttgact gatatattag
    27961 tttgcttatc agaaaaacaa aatggacgga ggaataacat gagtgatatt attattggta
    28021 ttttgttagt tatctcattc tttttcatgg tctggtactg tgtaaaaggc tacaacttga
    28081 tggtcggctt tgccatcatg gctactgtat ggatgggatt agcgctagtc ggaaacacgt
    28141 tttcaccaaa cccggcgatg gaagggcaag gagtaattga tgtgttgacg catatctata
    28201 cgacggggcc agctgagtac gccaaatcga tcttggtaaa tgtcttcttt ggtgcctttt
    28261 tcgggcgtgt tctagtagat agcggaatcg cagctaccct gattcgaaag gtagttgaac
    28321 ttggagggga caagccaaga atcacgatga gcttactatg tattgtaacc gctgttatat
    28381 tcatgtcgat gacaggaatc ggaccagtga tttctattgc agttattgtg ttgccaatct
    28441 tgatgtcatt aggtatttca gtaccggttg cactgttctc atttatgggc tcgattatgg
    28501 ctggaatctt tgctaatatc gtcaatttca aacaatatca aacgatttat gctggtttca
    28561 atccagcggc tgaaagctat acttataatg actatttcca aattggtatg attgggatga
    28621 ttgtaagctt agttgtggta ctaacggtcg ctaatatatc aatgaacaaa aagaaacgct
    28681 atgcaatggc agcaaacgta ccagctgaag gtggcgacgc accaatgatc tcatggttag
    28741 ccgtattatt accagtttta ggggtcgttc ttttagatct tccaatcatc ttaggtttta
    28801 ttctagcagg tatctgggca ttgctgttta ctggaaaatt gcgcggaggt tataaagaaa
    28861 tctgtcgtca gtttgcgaaa ttatttacag atggcgcagt agatgttgcg ccaatggttg
    28921 gtttcttgat gaccttagcg atgttcaata attcagctgc gtatgcttct ccttattttt
    28981 cagctatttt tggagattgg ataccgcaat caccattagt cttggcaatc gtatttgcta
    29041 tattgacacc actaggattt ttccgcggtc caatgaatct agtcggttca ggctcagcta
    29101 ttttagctgt cgtattagct gttaatccaa cgatgtcgcc agcctttttg ttcccgttat
    29161 ttgcaatcac aacgattgct cctcagcatt tagatattac acaatcttgg gttgcttggg
    29221 gattaggtta tacaaaagta acttctcgag aatatatgaa gaaatccatc ccaactggtt
    29281 ggatcatcgg agcgatctta tgcctgatca cgttcttatt gtacgggaac gcctagtaaa
    29341 caaaacgtcg ataaaaacga ttagatgaat ggaggaaaag aaaatgaaac gttttgtgcg
    29401 aatgggaatt gatgttggcg gtacacatac gaaagcagtc gcaatcgata atgcgacgca
    29461 cgaaatcatc ggaaaatctt cagtgaaaac aacccacgat gatgtccgtg gagtagccgc
    29521 aggtgtcgtt cagtcttttc aaaattgttt gctggaaaat aatatcagtc cagaagatgt
    29581 tgtgtttgtt gcacattcta ccacacaagc gactaatgca ctgattgaag gagacgtagc
    29641 aaaagtcggc gtaatcggga tggcaaaagg tggattagaa ggttttttag caaaacgaca
    29701 aactagattg aacgatatcg atttagggaa taagaaaaaa atagagattg tcaatgcatt
    29761 cttacctgtc aaacacttaa atgtagaccg tgtttcagaa acgatttctt ctttagaaag
    29821 agaaagagcg gaggtcttgg tttcttctat ggcatttgga gtagataatg gggaaccaga
    29881 acgagttgtt tatgaagcag catcggtaaa atcgatccct acaacgatgg cttctgacat
    29941 cacaaaatta tatggattga caagaagaac tcggacagca gcaatcaatg catctatttt
    30001 accaaaaatg ctagatacgg caacctctac agaagattcc gtacgagaag caggggtcaa
    30061 tgtttctttg atgattatgc gcggagacgg cggagtaatg gaaatcaatg aaatgaaaaa
    30121 acgacctgtt ttaaccatgc tttccggtcc agcagcatca gtcatgggct ctttgatgta
    30181 cttgagagcg tctaatggtg tttattttga agtaggcgga acaacaacca atatcggggt
    30241 cattaaaaat ggacgtccag caatcgatta ttcaattgta ggtggccacc caacatatat
    30301 ctcttcatta gatgttcggg ttctaggtgt ggcaggcggt tcgatggtac gggctaatca
    30361 gtcaggaatc atcgatgtcg gtccacgttc tgcacatatt gccggtctag attatgcagt
    30421 atttacggag acagaaaaaa tcaaaggtcc taaggttgaa tttttctctc ctaaagaagg
    30481 agaccctgct gattacgtca aggtagtgat ggaagacgga gaagaagtga ctattacaaa
    30541 tacatgtgca gccaatgtcc ttggattagt gcaagaagaa catttttctt atggaaatgt
    30601 cccatctgca cgaaaagcca tccaagcatt agctgattat tgtcatacga cggttgaaga
    30661 catcgcagaa cagatcatgg aaaaatccta tgctaagatt gaaccggtga ttttagaatt
    30721 ggcagacaag tatcacttgg agaaagatca gatttctctt gtaggtgtag ggggcggcgc
    30781 tgcctcattg attacttact ttagtaataa aatgggtgtg aaatattcga ttcctgaaaa
    30841 cgccgaagtg atttcttcta ttggtgtagc acttgcaatg gtccgagatg ttgtagaacg
    30901 tatcatccct tcgccaagta aagaagatat acgatcgttg aaaaatgaag cgatgaataa
    30961 agcgattgaa tcaggcgcta caccagaatc gatcgaagtc cacgtagaaa tcgatccaca
    31021 gacttcaaaa gtaacggcta tcgctactgg ttctacggaa gtgaaagcaa ccgatctaac
    31081 caaggagatc acaacagaag aagcactaga gcttgctgca gaggatatgc gattaaataa
    31141 aaatgaagtt tgcttattgg aaaatacacc tttcttttat gtatgcggcg aacagaatcg
    31201 ttcaaaaaat gctggaagtc ttcggatcat cgatcaaaaa ggatttatca aggtccaacg
    31261 tggacatgct tcatgtatga aaacaactgc agccaattat atgacagctg tcgaacaact
    31321 ttgggaagat atggcagttt atcaaactga attgattgcc cgaccagaat tttatctctg
    31381 cttaggagca agagtctctg attttacagc gacggatctg gaacaactac agcttttgat
    31441 ggatctggaa gtatctacta tggaaccgga ggaagaagtg atcgtcgttg ccggaaatat
    31501 caaacaaaca taagttagaa gagttactaa acgaattaca acagatcccc gaagaaattt
    31561 ggggattcta ccagtttcgg cgagatttat tttggaaaaa gattcctttg tccaagcaga
    31621 aaattcttat acaacaatca atcgattgtg gtatcgaaac ggcatgtagc atcaaaaaaa
    31681 agtacccttt tgccgatgta ggagaaattt gtgaacaaat ggctgttcca atcgtttcct
    31741 gtgaatcaga gcaaataaac gaacgaatca cttttgcaac ttatgcagaa gatgaaggga
    31801 ttcgattgat gacggagccg ttagaaaaat taaaatgttc aggactagct tcgatctcta
    31861 aagaaacagc gcaagctttg attattggac atgaactatt tcaccacatc gaagcttctg
    31921 ttaagggaat ttatacgcaa agcgaaaaaa ttgtgctgtg gcggttgcct ttttatacac
    31981 atcaatcaaa cattcgtgca ttgagcgaga tagcagcgat gagtttttca aaagagatga
    32041 atcaaagcga tttttcgcct tatgtattag aggcagtctt actttggcca tataatgaaa
    32101 ttcgtagcca agggatctta gaagaaataa aaaaaataga aaaaagatgt acggagtatg
    32161 atttagatta caaataaaga gactgtgaca aaagtcgtgt cacagtcctt tttttccgaa
    32221 taaacgatgt tctcctgtca actcctcggt cacaagtcaa aatattcaac aaacatgaga
    32281 agctgttttt tgaaattgtt ccttgtgact cggagatgaa cggcaggctc acgacctctt
    32341 ggaaaacggt gttcaaaagc ttgcatctgc ggtaataagt ccagccaagt taaaaacata
    32401 agaagctatt tttacttggc tgttcttatt acttgatgca gggcagcttt ttcacaacct
    32461 ctcaataaac ggtgtgcaat cagctgaccc tcggtattag ctcaaaaaaa acggcaaaat
    32521 atgaggaact attttgccgt ttctttctct aatactcagg tcaaaacgct gattccaaaa
    32581 cctcttattt gatgggtctg tcctgaatat cttcaaaata atcggggtaa ttatgaatca
    32641 cgtattcttg ctcctcgata atcatatgta aatgcatcgt gcaaagaaat ccgacttcat
    32701 caaagttatg atcaatcatt gattgaagca ttgtctgatg ttcatctaat actcgacccc
    32761 agtctaattc tgaaatcgtc aaacgtaacc atctgaaacg cgtactataa ctttctagcc
    32821 aatcccaaat ttctcgtttt ccagcaattt cataacaagt tcggtgaaaa tcagtatcca
    32881 aatcaaaaaa agctttttta ttttgagcga ttactgcctg atcggtttgt tctagtattt
    32941 tttctagttt agcttgatct tgcttggtca ttttcgcact gcattcttgc aggatcggtt
    33001 tttccaactt ttcccgcgta taacgggcta atgaagcaga tcggatatcg atttttgaaa
    33061 cataagtgcc ggactgtgga atggttttta caagctcttg attgcgcagt tggatcagtg
    33121 cttctcgaat cggtgtacgc ccgatagcta gttgttcttc taacacttta tcggagattt
    33181 tacttccagg tgctaactcg gaataaatga tttgtttacg tatagattca taagcttgct
    33241 gttgcaaatt attgataacc atttaacctt cctttctatg cagatataat ctattataac
    33301 ataaatcgct tacaaatcgt gtgggcataa aaacacagtc tgcaaaaaaa gccctgatag
    33361 gcatgcctat tagagcctcg aaaagaaaaa tattgaatca atctggtcgt acctcttgga
    33421 tcggtttgac acgaccgccg attcttttag caaaagcttc ggattctttt ttgtctttga
    33481 aaatgagcag attgtctaag tttttttccc gagtgcgaca gccagtttta tcgatgtaac
    33541 cgtgcattac tttaacgaca tacatgggga tcacctgctt ttttcttttc attatacgaa
    33601 ctactcgaca caatacaaga aaaatgctta gacggtcttt attaagaatt tacatcatcc
    33661 aaagaagcgt acgcttggaa taactgatct aactccggat tgactttgct cagcttcact
    33721 aatcgttgcg aatcagaaag taaaaaacag tgtttactac tgccagtagt ttttaatttt
    33781 ttgtcttcag ttcccacaat ttcgtagcta aaatccaacc gtgtccccgt atacttttgg
    33841 atagttggat ggatgctcac tttttctccg taatggatca tttctttata gctgcaattt
    33901 acttccagaa cggggatgat gatcccagat tcttcgattt ttttataggg aaaccctaga
    33961 tgtaccaata aggctacccg agcctcttca aaccagcgga tataattgct gtgatgaata
    34021 atccccattt gatctgtttc ataataaaaa ggttctcgca cataacctgt aaatttctcc
    34081 atgactcatg cctcgttttc cattgatttt ttacaaaaat aattcatcca tttcggaagt
    34141 gcttcgctga tttgtgtcgg caaaacaata tattgttctt ttgccagctg gtctccaatg
    34201 aaactatgaa gataaatagc tgctgcaatc gtttggtcat tttgaggaaa ctgggctaaa
    34261 aatcctgtga tcatcccagc taaagtgtca cccatgccgc ccgttgccat agcagcagaa
    34321 cctaaaggat tggtgtagaa gtgctggtga ccataaattt ttgtctcatg acttttcaaa
    34381 acgagcacag caccgatttc ctgttgcttc tttttgtttt ctttatcccg ttgttcttgt
    34441 atcggtagag aactcaaccg ttgccactcc atttgatgag gtgtaagtac agtttgttcg
    34501 ggatagggta gcaaaagatg attagcagca agtaaactta aagcagagcc atcaatcacc
    34561 agccattgtt cttttgattg gttttctagt acttgtttga aacgttccaa actcttagaa
    34621 gaagtaccca atccgggacc aatcaagagt acatctgctt gctttattac ggaaagaaac
    34681 tggtcagtat ccgtccaaac tacaatcatt gcttctggca gatgactgtg aagagcactc
    34741 cgattttttt catcagttac tacagtcgtg agacccgctc cgctgtgtac ggcagctaaa
    34801 gcactcataa tgattgctcc gccatattgt tcattgccgc caatcaaaac gatacgtcca
    34861 aatgttcctt tatgtgaaat ttttggacga ggtgtgatga ctcttttcac tagttgttcg
    34921 tttatcagca tctaaaaacc tccttttact cattatagcg tatatttttt ttagagaaaa
    34981 acagataaga aaaggaattg tcagattttt tgaactattt ttttctgtaa tttgtggtat
    35041 catgaacacg aagacttaaa taagtggagg attaacttta tgacaattga ttggcaaaaa
    35101 gaagtagaag cacgtaaaga agacttgctt gaagacttga aaaatctttt acgtgtcaac
    35161 agcgagcgcg atgactcaaa agtaacacca gatgcaccat ttggacctgg acctcgcgac
    35221 gcattgaaac atatgttagc ttatggcgaa cgtgatggat ttaaagtaaa aaatgtcgat
    35281 aactatgcag ggcatattga tcttggcgaa ggagacgaaa cgctagggat atttggacac
    35341 atggatgtcg ttcctgcagg agatggctgg gacacagatc cttatgaacc agtaatcaag
    35401 gatggaaaga tctttgcacg cggatcaagc gatgacaaag gtccaagtat ggcagcttac
    35461 tatgcgatga agatcattaa agaacttgac ttgaaactat caaaaaaagt tcgcttcgta
    35521 gtcggcagcg atgaagaaag cggctggggc gatatggctt attatttcga acatgaagaa
    35581 gaaccagatt ttggtttctc accagatgct gaattcccaa tcatcaatgg tgaaaaagga
    35641 aatgtttctt tagctttacg cttcaaaggc gacaatgcag gagattatgt cttgaaatct
    35701 tttgtttccg gacttcgcga aaatatggtg ccaggaacag caactgcagc acttcaagta
    35761 ccaagtgcag atgcagctat cgcgatggaa gaagcatttt accaattcat cgaagcaaat
    35821 ccagtaagcg gaacgattga agcggacaat acgtatgtaa aaatcgaatt agttggtaaa
    35881 ggcgcacatg gtgcaagccc acaatctggt atcaatgcag gttctttctt ggcattgttc
    35941 ttagataact atgaattcct aggatctgct aaacaattta tccatgtagc agctgcttat
    36001 gtccatgaag atttttatgg agaaaaacta ggagtcgctt atgaagatga aaaaatgggc
    36061 aaattgacaa tgaatgctgg actatttgct tttgaagaaa atggtacaga ggaagcgaac
    36121 ttcatcaata tgaatttccg ttttccaaaa ggtgtaacag tagacggatt gcaaagtgac
    36181 atcgaacaaa cagtggggca agaaggcgca acagttactc gaggtgctcg cgtaatggaa
    36241 ccacattacg taccaatgga tgatccattg gtggctacat tattgcaagt ctatgaagac
    36301 cacactggag aaaaaggcta cgaacaaatc atcggtggcg gaacttacgg acgtttgttg
    36361 aaacgtggcg ttgcttatgg agcgatgttc ccaggatata ctgatacaat gcatcaagca
    36421 aacgaattta tgagtcttga tgacttgttc agagcaacag caatctatgc agatgccatc
    36481 tatcgtttgg cgaaataatt aattaaaaag aggatcaaga attgcaaatt atttttgcag
    36541 tcttgatcct ttttttactt tctactgtgg tattcatgat aaacatgata tagattcaat
    36601 tcatattctt tcttagcgtt cgtgacgact gtatccaaaa tcaaccctgt tactaatgaa
    36661 agaagtgcta aagtcatcaa tccagtactt aaaatcgcag aagggatgcg tgtaataaag
    36721 cttgtcagca tatattcgcg aatcacagga atccccgtga ccaatccaaa taaaaagaag
    36781 aagatggtcc aaatcccaaa gaaaagcaaa ggcttataat ctttaaacat tttaataatc
    36841 atcatgatca ctttgaatcc gtcagagaat gtattcaatt ttgattcgct gccttcagga
    36901 cgatcacgat aatcgattgg gatttcaacg aacttgaatt ttttatctaa agcatggatc
    36961 gtcaattccg tttcgatttg aaaaccagaa ctcataatag gaaaactttt gacaaagata
    37021 cgattgaatc ctcgatagcc ggtcatgaca tcaagaattt ttgttttata cattctagta
    37081 attgtatttc taacaaggtt atttccaaaa tcgtggaaag gtctcttatt ctcatcaaag
    37141 taggttccat ttgataggcg atcaccaatg accatatctg cttcaccaga acgtaatttc
    37201 tcgagcaaac catgtacagc ttctgcagga taagtatcat cgccatctac cattaaataa
    37261 tagtcggcat cgatatcaaa gaacatttgg cggatcacat ttccttttcc ttgacgaggt
    37321 tcttttttta cgattgctcc accttgaacg gccaattcgt atgttcgatc ggtcgaatta
    37381 ttatcataga cataaatatc tgcttctggt aattctcgtt taaagtctgc aatgactgtt
    37441 gaaattgttg cttcctcatt gtaacaagga atcagaacag caattttttc ttgttgttcc
    37501 atttttcact ctccttaact atagaaaaca aaagctaaat taaaaatacc tcataatcaa
    37561 aggaaatgct agtttttccc gctaaatatc atttatttaa aaagaaaata ctggaatata
    37621 tgtttggaaa gctctatcta aaaaaccacc cactacaaaa gaaggacatg atacctctct
    37681 tttgaatagt gggtgcgtat tcgttctctc acttttttga cgtattaatc tgttgcacct
    37741 ttttttcttg aaatttctaa tacggttcct gtatgagcat ctgctaaaaa ttcataataa
    37801 acagtttcgc catcttctat tcgagaaaga cctccccgat aagcactcga ccgaacggcg
    37861 aatttcctaa taggttcctt ttcaaaagag atccaagaac cttcgattgc accttctttt
    37921 agaaaagatg acttgatatt ttcaagtact tggtctgctg acaatacttt tttgcgatga
    37981 taccaaatcg ttgaagctac cccgctcaat aatcctagac cgattccaac tgctaacccg
    38041 cctttaaaat agcttagttc gctttcttca tacatgtgga catacctcct tcttctcact
    38101 tgttactcct tgtgcttatt ttaccacact ctcatatttt ctttgaaata aataaccgct
    38161 accagaaaaa ataagctata ataaatacga tcggtctgca gaaaaaatca tattttatcc
    38221 gcagatcaat ataagtctga gaggagttta gtctgaaatt tagacgaata gcatatggaa
    38281 gaaaaaacat ttcaacgaat caaagagtta acagaattac aaggaacaag cggttttgaa
    38341 caagatgttc gcgcttatat ggaaagtcat atggaaccgc tggtagatga gttacagtta
    38401 gatggtttgg gcggcatttt tggtctgcgc catcatgaag aagcggatgc accccgtgta
    38461 atggtcgcag cacatatgga tgaagtcgga ttcatgctga cacaaatcca agaaaacggg
    38521 ctttttaaag tcgtacctct aggcggctgg aatccttacg ttgtttctgc tcagcgtttt
    38581 acacttaaaa cctctactgg taagaattat ccatgtattt cttcttccgt tcccccacat
    38641 ttattgcgag gaacaagcgg acaaaaatca gtagaagtaa ccgatatttt gttcgatgct
    38701 gggtttgaat caagagaaga ggcaatgagt tacggtgtcc ttccaggaga cacaatcgtt
    38761 ccttacgctg aaacgatcaa aacagccaac ggaaagaata ttatcagtaa atcatgggac
    38821 aaccgctatg gctgtacaat ggtattagaa gctttagaag cgttgcaaaa tgaaacatta
    38881 ggtcatacat tgattgcagg cgcgaatgtc caggaagaag taggcttgcg tggttctaaa
    38941 gcttctgtca ataaattcaa gccagatctg ttctttgcag tagactgctc tgcagcagat
    39001 gatacagtga cgaaaaatgg cacattcgga catttaggag aaggtacatt gatgcgtatc
    39061 caagatccag gtttgatcat gcttcctcgt ttgcgcgagt acttgctgga tatcgctgaa
    39121 acaaacaata tcccttatca atactttgtt tcaaaaggcg gtacagatgc aggtgctgct
    39181 catacacaaa acgaaggaat cccaagtaca gtgattggcg tagtgggacg ttatatccat
    39241 acgcatcaaa cgatgttcag tattcgcgat tttgaagctg cacgagaaat gttgattcaa
    39301 acactgaaag gtttggataa atcaacagta aatacgatcg tatacggaaa ataatgcgat
    39361 agtgaaacta taaaatctgg caaaagattg ctttttgcca gatttttttt ataaaaagag
    39421 gatcaatgtt tgttagttcg aaagaaaggt gtataattta attgaaaaat acataaacag
    39481 aaagtagagg acaaagaatg attatcccaa atagtttaga agaattagca ggctacgtag
    39541 aaactggaaa gagtgtattt ttctttactg ccggctggtg cggagactgc cgttttatca
    39601 aaccgcaaat gcctgaaatt gaaaatgact tttctgattg gcaatttatt gaagtagacc
    39661 gtgacaagta catagatgta gccgctgaat ggaacatttt tggtatccca agttttgtcg
    39721 tgatccaaga cggaaaagaa ttaggtcgtc tagtgaataa agatcgtaaa acaaaacagg
    39781 aaatcgaatc gttcctagaa agtgtaacaa aaggctgaca tctgttagga ggggtcaaga
    39841 tgaatcaaga atataagaat attttagtag gtatcgacgg tagtgaacaa gcacttgctg
    39901 ctttcaaaaa agcggtagaa gtggctcgcc gtaataatgg gaaagtatat gtagcaaacg
    39961 taatcgatca gcaattttat aactttatgg gctatgcacc tattgatcaa aatctagtcg
    40021 atcagcaaac tgaaacagcc aaggaaatga tcgaagaatg taaagaatat gggaaatctg
    40081 ttgattacac aaatatagaa ggaattattg catatggttc tgttcgtgaa tccatggcag
    40141 tcaaattgcc aaaaaaatat gagatcgatc taatcatggt tgggcagtca ggtctaaatg
    40201 cagtcgaacg ctttatgaca ggaagtgtag ccagctacgt gatacgtcat tcaccttgtg
    40261 atgtcttgat cgtttctgac gaagaagaac agccaagtaa ttaagcaagt ggaacttgta
    40321 cgaccttttt aatcaattaa ctaaaacagt aaagggactg tgacaaaagt cttgtcacag
    40381 tcccttgtta cgaataaatg gtgttccaga agaggcttct tcggaaataa agcatgaaaa
    40441 aaatttcatg cagtgaatgc aattttttgt taagataaat ctcagcaaag gataatggag
    40501 gaaagaacat gatttttgct tataacaaag cacacgtcgg agacaccttg atggttatta
    40561 tagccgacga taaaggaaca gaaaacactg ttgaacgcaa atggaatgtt gctcggatca
    40621 aagatgaaca aggtcaagtt gttgcttgga actttttcca tatctccgat catctaacaa
    40681 tcgaagggaa cggccaagta agcttaacag atgaggaatt agcgaaattg aatcgattga
    40741 tcaaagaagc aggattcgaa gaacagcttg aagctgatca tgaaccgaag atcgttgtcg
    40801 ggtacgtaaa aacatgcgtc ccacatcctg attctgacca tttatcgatt actgagacag
    40861 aagtagacaa tggtacagta ttgcaaatcg tttgcggtgc acccaatatc gaagctggac
    40921 aaaaagttgt cgttgcaaaa ccaggagcta tgatgccaga tggaatgatg atctggccag
    40981 gaactttgcg aggggtagat agctatggaa tgatctgttc cgctcgtgaa ttgcatttgc
    41041 caaatgctcc agcaaaaaaa ggaatcttag tattgcctga ggatgccgta gtcggagaag
    41101 catttccaaa ataaagaggt tgtgacaagt ctttgtcaca acctcttttt tattaatttt
    41161 cactattttg attttgtttt aatgccgatt gatcgatcgt caattcaaca gtagttgttt
    41221 tttctttcga gccttcatag taagtgattt tgacagaatc tcccactttt ttcttataca
    41281 aagcagattg aagttctaca ccagaagaaa cttctttgtc atcgatctta gtaatgacgt
    41341 cgtattgttt caatccagct ttttcagccg gtgtagctgt ttggacattt gtcacgatga
    41401 caccgttagt tacagatgaa ggaatcttca agatttgttc ttgttgctga gtagaaacgg
    41461 cagataagtc gaccattgtg atacctagag ctggacgtgt cacttttccg tctttttcca
    41521 gttgattgat gatattcact acatcgttac ttggaatagc aaatcccatt ccttctacgc
    41581 ttacattaga agtagattca gaagtacttg cgatcttact tgagttgata ccgataactt
    41641 gtccttcgat attaactaaa ggaccaccag aatttccagg gttgattgct gcatctgttt
    41701 ggatcgcatt gatattgact gtttcgttcg attcattcgt acttgtcact tgtcggttca
    41761 aggaagaaat gattcctgaa gtgacagaat ttgcatattc agatcctagt ggggaaccaa
    41821 tcgcaatcgc aggctcacca accttcagag cacttgagtc accaaaagag gcaactgttt
    41881 cgactttgtc tgaattgatc ttcaacaccg ctaaatctga ataagcatct gttccaacta
    41941 attcagcttt taccttcgta ccgtctttca tcaagacttc aagaccttgc tggccatcta
    42001 ctacgtgatt attcgtgact acataagcag tattcccgtc ttttttgtag atcacgccgc
    42061 ttccttcact ataagcttcc aaattactat catctgagct gctactttct tcttgctgcc
    42121 cgaatagtcc gccaaaaccg cttgattggt tttgactttg taagttgata acagaaacga
    42181 cagcgtcttg aactttatct accgctttgg tgatatcaga atctacattg actttgacat
    42241 tttccacaac tgtttcaccg gcagaattct gattgccgct tgtagcagta gaactattgt
    42301 tgccagtgcc catcgctgca taaaaaatgc cagctgtcag tagtcctcca acgatccctc
    42361 caacaagccc cagacctaac ttacgccaga ggctattatt tttacttttt ttcatctttg
    42421 gtgtcacatt ttttctatcc atgtgttcct cctccaatta cattcattta tctactgtta
    42481 gtatagtctt atttgttgac tttagtctac tttgagactg tgaacttttt atgaaaaact
    42541 ttaggaaaaa tcattgtttt cagatgaaaa tatttgattt tctttttcca cagatactgt
    42601 gtaaaactac gcggatagga ttggaaaaat aagggataaa acatatccac agcctgtgta
    42661 taaagtggat aaattcttat aaaacgtatg tttgcctaat gaatgtgatg aaataaggta
    42721 aaataacact gttttctgtg gataaacctg tggatgttgt gcataactgt tggggaaatc
    42781 tttttaacaa aaatagccaa aataaacata tagacgaaaa aattgattat aataaacaaa
    42841 gtgagcatga agaccaaagg agagaaaaca tgaatatcaa aattatctca gtaggaaaat
    42901 taaaagaaaa atacctgatc caaggtatca atgagtatgt caaacggctg aatgcctatg
    42961 caaaaatcga attgatcgaa gttcctgacg aaaaagcccc ggagaattta agcgaagcgc
    43021 aaatgagaca agtaaaagaa aaagaagggg aacggatctt agcgaaaatc aaagaacaag
    43081 aatacgtcta tgccttagca attgaaggga aaaatcctac aagtgaatct tttgctaaac
    43141 aaatcgacca attaggtatc caaggaaaaa gccaccttgt ttttgttatc ggcggctctt
    43201 taggactcag cgaagccgtc atgaaaagaa gcaatgctca gatctctttt ggaaaaatga
    43261 cgtatccaca tcaattgatg cgtctgatcc ttgtcgagca aatctaccgt gccttccgga
    43321 tcaatgcggg ggctccatac cacaaataat gatatttttt aagagaaaaa attatcccta
    43381 ttttaaataa tagcaatagg tagtggtagg gagaaattta taaataactt ttttatttgc
    43441 tttggtagcc aagtaagttg caaaagaaaa atagatactg ttaaaaagat aatgtagaca
    43501 tagaaacaaa tacgtaaaat tttagttaga ataatggcaa ggagaaaaaa catgatagat
    43561 gaaaaaaagt gtttaaaaaa tctattagag gatatggatg atattgaaga aaactatcta
    43621 aatggactgg gaaaacaaat atatttcaga tacttaagct atctaaaaat gaaataagac
    43681 atagtaattt tttagctttt ttgtttgctc caaatgaaac ccacaattta tctgatgagt
    43741 tttttaaaat gtttttgaaa aggtatatag attctaatga tgataccaaa gctgctatca
    43801 attattttga tgctttactt aatagctatg aagatttaat tgtttacaga gaaaataaga
    43861 atattgatat tttattggta tcggaaaaaa ataaaatagt ggtgtgcatc gaaaataaaa
    43921 ttctgtcttc ggagtctgga gggcaactta ataaatacca aatatatata gaacgcaatt
    43981 attctaacta taaaaaaatt tttgtttttt taactccaga tggaaatgaa cccacaaatc
    44041 ctagttgggg cataattact tacaagaata tcgttgaaga gagtgtaaaa tattttgtgt
    44101 aaatagaaaa aaggaagtcc cttctgtaga atagagttac cacaacacat tcacagaaaa
    44161 gaggacttcc atatgaacga ttttactaca gaaattatgg aaatactaat caataaaggt
    44221 gatttggatg atttgtttcg tcgtcaccta gaattggcta ttaacgcttt attacaagct
    44281 gaattaacgg tatttcttga ctatgaaaag tatgatagag ctggatttaa ttcaggtaat
    44341 tcccgtaatg ggaattattc gcgctctttt aaaacagagt acggtgaatt gaatttagta
    44401 atacctagag ataggaatgg agacttttct caacaaactt tacctgctta taaaagaacc
    44461 aatgactctt tagaaaccac tattattcag ctagttcaaa aaggaattac tatgtccgaa
    44521 atctctgatc taatcgaaaa aatgtatggt cattattaca aaccacaaac tatttcaaat
    44581 atgagtaaaa ttgtgtctga agatgtttcg gcatttaaag aaagaacttt agaagctaaa
    44641 tactcagtca tttttatgga tgctactcat attcccttaa aaagacaaac cgtatcaaaa
    44701 gaagctgtct atatagtaat tggtatcagg ttggatggaa ctaaagaggt tctaggattt
    44761 actatagctc caactgaatc tgcttatgtt tggaaagaga ttcttcaaga tctaaaagac
    44821 cgtggtttag aagaggtttt gttagtcgta acagatggtt taagtggtat tgacgatagt
    44881 attcatagtg tttatccaaa tgctcaattt caacaatgtt gtgtccatat atctagaaat
    44941 atcgctcata aggttcgtgt tagtgatcga caagaaatct gtagcgattt caaattagtt
    45001 taccaagcaa gttcaaaaga agaagcaaat aatcaaataa ggtttatgat agataaatgg
    45061 aaaaagcagt atccacgagt ggttaaattg ctcatgaatc ctgctatatt aaccttttat
    45121 aatttccctc cgtcaatcag aagaactatt tattcaacta atttgattga aggttttaac
    45181 aaacaattaa agaaatatac caaaagaaaa gagcaatttc ctaatgaaga atctctggag
    45241 agatttctag tatctcaatt caacaactat aatcaaaagt ttctatgccg agttcataaa
    45301 ggttttaaag aaatacatga tacattagaa tcaatgtttt aacttgatca acaga
//
LOCUS       DAFLVO010000015        44799 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.015, whole genome shotgun sequence.
ACCESSION   DAFLVO010000015 DAFLVO010000000
VERSION     DAFLVO010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44799
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.015"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(2..1012)
                     /locus_tag="L1U99_000876"
     CDS             complement(2..1012)
                     /locus_tag="L1U99_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBN1211437.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(1192..1536)
                     /locus_tag="L1U99_000877"
     CDS             complement(1192..1536)
                     /locus_tag="L1U99_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBN1211438.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(1529..1963)
                     /locus_tag="L1U99_000878"
     CDS             complement(1529..1963)
                     /locus_tag="L1U99_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HBN1211439.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            2101..2838
                     /locus_tag="L1U99_000879"
     CDS             2101..2838
                     /locus_tag="L1U99_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1211440.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            2831..4042
                     /locus_tag="L1U99_000880"
     CDS             2831..4042
                     /locus_tag="L1U99_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1211441.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            4246..5028
                     /locus_tag="L1U99_000881"
     CDS             4246..5028
                     /locus_tag="L1U99_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HBN1211442.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            5098..5760
                     /gene="trmB"
                     /locus_tag="L1U99_000882"
     CDS             5098..5760
                     /gene="trmB"
                     /locus_tag="L1U99_000882"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBN1211443.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(5858..7612)
                     /gene="ade"
                     /locus_tag="L1U99_000883"
     CDS             complement(5858..7612)
                     /gene="ade"
                     /locus_tag="L1U99_000883"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBN1211444.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            7744..8673
                     /gene="tadA"
                     /locus_tag="L1U99_000884"
     CDS             7744..8673
                     /gene="tadA"
                     /locus_tag="L1U99_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HBN1211445.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            8630..9679
                     /locus_tag="L1U99_000885"
     CDS             8630..9679
                     /locus_tag="L1U99_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HBN1211446.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            9676..9954
                     /locus_tag="L1U99_000886"
     CDS             9676..9954
                     /locus_tag="L1U99_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBN1211447.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            9929..10399
                     /locus_tag="L1U99_000887"
     CDS             9929..10399
                     /locus_tag="L1U99_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBN1211448.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            10416..10718
                     /locus_tag="L1U99_000888"
     CDS             10416..10718
                     /locus_tag="L1U99_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211449.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            10735..11106
                     /locus_tag="L1U99_000889"
     CDS             10735..11106
                     /locus_tag="L1U99_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HBN1211450.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            11078..11437
                     /locus_tag="L1U99_000890"
     CDS             11078..11437
                     /locus_tag="L1U99_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211451.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            11609..12616
                     /locus_tag="L1U99_000891"
     CDS             11609..12616
                     /locus_tag="L1U99_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1211452.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            12641..13825
                     /locus_tag="L1U99_000892"
     CDS             12641..13825
                     /locus_tag="L1U99_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBN1211453.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(14262..15845)
                     /locus_tag="L1U99_000893"
     CDS             complement(14262..15845)
                     /locus_tag="L1U99_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBN1211454.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIVLVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(16423..16566)
                     /locus_tag="L1U99_000894"
     CDS             complement(16423..16566)
                     /locus_tag="L1U99_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HBN1211455.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(16789..17268)
                     /locus_tag="L1U99_000895"
     CDS             complement(16789..17268)
                     /locus_tag="L1U99_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBN1211456.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(17341..17625)
                     /locus_tag="L1U99_000896"
     CDS             complement(17341..17625)
                     /locus_tag="L1U99_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211457.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(17703..17897)
                     /gene="ssrS"
                     /locus_tag="L1U99_000897"
     ncRNA           complement(17703..17897)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="L1U99_000897"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(17969..19255)
                     /locus_tag="L1U99_000898"
     CDS             complement(17969..19255)
                     /locus_tag="L1U99_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBN1211458.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            19393..20064
                     /locus_tag="L1U99_000899"
     CDS             19393..20064
                     /locus_tag="L1U99_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBN1211459.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            20030..20518
                     /locus_tag="L1U99_000900"
     CDS             20030..20518
                     /locus_tag="L1U99_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HBN1211460.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            20531..21478
                     /gene="prmA"
                     /locus_tag="L1U99_000901"
     CDS             20531..21478
                     /gene="prmA"
                     /locus_tag="L1U99_000901"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBN1211461.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            21479..22243
                     /locus_tag="L1U99_000902"
     CDS             21479..22243
                     /locus_tag="L1U99_000902"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBN1211462.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            22476..24689
                     /locus_tag="L1U99_000903"
     CDS             22476..24689
                     /locus_tag="L1U99_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBN1211463.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            24700..25146
                     /locus_tag="L1U99_000904"
     CDS             24700..25146
                     /locus_tag="L1U99_000904"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBN1211464.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            25317..26576
                     /locus_tag="L1U99_000905"
     CDS             25317..26576
                     /locus_tag="L1U99_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HBN1211465.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(26665..27612)
                     /locus_tag="L1U99_000906"
     CDS             complement(26665..27612)
                     /locus_tag="L1U99_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBN1211466.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            28006..29298
                     /locus_tag="L1U99_000907"
     CDS             28006..29298
                     /locus_tag="L1U99_000907"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBN1211467.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            29313..31082
                     /gene="aspS"
                     /locus_tag="L1U99_000908"
     CDS             29313..31082
                     /gene="aspS"
                     /locus_tag="L1U99_000908"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBN1211468.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            31191..32066
                     /locus_tag="L1U99_000909"
     CDS             31191..32066
                     /locus_tag="L1U99_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1211469.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            32332..34215
                     /locus_tag="L1U99_000910"
     CDS             32332..34215
                     /locus_tag="L1U99_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBN1211470.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(34290..34574)
                     /locus_tag="L1U99_000911"
     CDS             complement(34290..34574)
                     /locus_tag="L1U99_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBN1211471.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(34564..35298)
                     /locus_tag="L1U99_000912"
     CDS             complement(34564..35298)
                     /locus_tag="L1U99_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBN1211472.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            35427..36050
                     /locus_tag="L1U99_000913"
     CDS             35427..36050
                     /locus_tag="L1U99_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBN1211473.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            36242..37363
                     /locus_tag="L1U99_000914"
     CDS             36242..37363
                     /locus_tag="L1U99_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBN1211474.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            37370..40498
                     /locus_tag="L1U99_000915"
     CDS             37370..40498
                     /locus_tag="L1U99_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HBN1211475.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            40517..43711
                     /locus_tag="L1U99_000916"
     CDS             40517..43711
                     /locus_tag="L1U99_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HBN1211476.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(43857..44564)
                     /locus_tag="L1U99_000917"
     CDS             complement(43857..44564)
                     /locus_tag="L1U99_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBN1211477.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNNVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        14374 a         7958 c         9401 g        13066 t
ORIGIN      
        1 tttattttga tgaatcagtt gtttcttcag ttgaagattc ttttgttgaa tcagttgatt
       61 ttgtgtcaga actctttgtt gaagctgtag tttcacttga gtctttcgta cttgatgaag
      121 ttgttgtgaa tgcactcaac acattttcaa aggcatcatc tttgattttt acatttgcat
      181 cttttaattc ttcaccgatt actttagttg tgaatgcatt gtcacttagt ttagtttcag
      241 tagcgatatc ttttagttga tctttgtatt tatccatgtc attgccttta ttttggtttt
      301 tcaccatttt gacaacgtag tattctgtcg cataagaagt aggatttgtt gtagtaataa
      361 catcggagat ctcaccgtct ttcaatttga aagctgcttc ttttacttct gcaggaatag
      421 ttgttgtcgt tgagtcgaat ttaactttac cgccatcttc ttttgtctct gtatcagttg
      481 atttgtcttt ggctaattta gagaaatcat ctccatcatc cgctgatttt ttcacatctt
      541 ttgcttcatc ttcacttgat aatttgatga tttgtgcttc tacttctgga tggaaagatt
      601 tccaagcagt tttcaaatcg tcatctgtaa tatctacgtg agctttcaag ccagcttcaa
      661 aagctaaatt gttacgaata tattctttat aagtatcttt cgtatatcca gcagcttcta
      721 attgtgattc aaaagtatca cctaatgatt tcgcttgttt gtcgtattct gcatccactt
      781 gcttatcggt tactttatcg ccatatttgt tattgaatac tttataaatg atcatccgtt
      841 gtactaagga ttggttcgat gattcaagtt ttgcttcatc atagaaatca gatacagtga
      901 tcgttccgcc tttcatcgtt gcgatatctt tattagtatc gcctgaacaa gctgctagag
      961 ttaaaacagc caacgcacta gtagctgcca aaataattga tttttttttc attaaaattt
     1021 gcactcctgt aattagttat tatttttata tattaactat accatatccc atttccttta
     1081 aaaacgttgt cgtggtagtt tcaaacaaaa ttcaaaattt catcacattc ctaggaaata
     1141 cgcaaacttt tctcacttat atagttaaat ctgttgagaa aataatcatt attatatttg
     1201 ttcaggatac tctggcagat cagcttttag tttttctact tgttcattga tttgtgtgat
     1261 acgtggttcg gcttggaatt taaaatcttc gatatctttt ttgattgctt cttggaaagc
     1321 aggaatcaca gattcagctg tttcttttgt ttcgatcaat gcgcttttaa aatgattcag
     1381 gctgttattt aaatcatttg tcagagttgt tgcttcttcc aattcttcga tcagtttctt
     1441 tcttgtttca ttcccgctcc tgggcgccaa taacagacct ccgacagtgc cagcagcagc
     1501 tccaaataac agtcctttga aaaagttttt aatcatcgca ggacacctgc tttacgattg
     1561 tttcttgaat agcttttagt tcttccgatc cataactatc ttgatgattg acaaagtgaa
     1621 tagaaaaatc atcctctttg ctgtagcgag ggactaaatg gatatgtgaa tgaaaaacag
     1681 attgataggc tagttcacgg ttgttattca agatattaag acctttcatt tctggaaaag
     1741 ctttttccaa tgcttgagca atcttaggca cacgcgaaaa aacctctcct gcaagttcgg
     1801 gatcatattc aaaaatatct gctacatgac gtttaggcac aactaatgtg tgtcctttcg
     1861 ttgcttgaga gatgtctaaa aaagcataga ccttgtcgtc ttcatatatt ttatagcttg
     1921 ggatttcttg attgatgatt ttgcaaaaaa tacagttttc catataaaac atcctttcta
     1981 taaagaataa atacttcagc ttaactttac cataagttaa agctattgta aggaaaaaaa
     2041 caaaataccg tcattttctt cgtggtataa taaataaaaa taaatggcgg aggaaaaaga
     2101 atgagtttaa ttatcgatca tgtcacaggg gggtacggac atctccctgt gttaaaagat
     2161 atcagtttcg atgtacagcc tggagagata gtagggttga ttggactgaa cggagcaggg
     2221 aaaagtacga ccatcaagca cattatcggt ctgctggaag cttcaaaagg aacgatagaa
     2281 atcaatcatc tatccttaaa gaaaaatacg gaagaatatc gcaaacaaat tgggtatatt
     2341 ccagagactc cttctttata tgaagaattg acattgagag aacatatcga agtcactgcg
     2401 atggcctacg atatacctat ggatatagca atgaaaagag cagaaaagtt gttggagact
     2461 tttcggttat ctaatcgtct tgactggttc ccagctaatt tttcaaaggg aatgaaacag
     2521 aaagtgatga tcttatgcgc ctttttgatc gagccttctt tatatatcat cgacgaacca
     2581 tttttaggct tggatccact agctatcaat gcattgcttg aattgatggt agaaatgaaa
     2641 aaagaaggag ccggtatttt gatgtctacg catattttag ctactgcaga aaaatattgt
     2701 gatcgttttg tggtcttaca taacggagag atacgagcag acggttctct tgagatgttg
     2761 agaaaagaat ttcagctgcc ggattcttct ttggacgaaa tctatattgc tttaacaaag
     2821 gagcaggcac atgagtagtt tttttcaaaa acgtttagca agacatcaaa agaaaatgat
     2881 gaaatatatg cgttatgtat tgaacgatca ttttgtttta gtttgtcttt tcttgattgg
     2941 cggtgtggga ttatattatt ctaattggtt gaaaaccctg cagccaccgt ttgcaattgg
     3001 agggctcata atctctgtat tttggatgct ctgtttattc gtgggtaaga tggctacttt
     3061 tgcagaggca gcagatattg tttttttact tcctaaagaa aaagaaatgc aaacctattt
     3121 ggaacgagct tttcgctatt cttgcatttt tccgttgatc tttttgatat tggcatgcgg
     3181 attggccatg ccattagtgg tggttagtac ggagcaatcc ttttcgatgt ttttcgtcta
     3241 tctgatcata ttatggagtt tgaaattcag tcatctgcaa atcaagagag cagaattgtt
     3301 tcgactagat caacaagtta ttcgttattg gaaattaggc tggttttttt cttctctgat
     3361 ctttttgttt ctatcatttt attggctaat atgggcagga atagcaggtg cattagtaca
     3421 ggcaagtcta tattactggt ttttgtggaa gcaacaagaa aaaggattgg attgggagaa
     3481 aatggtgcat gtagaagaac ataggttgca tcagatctat caatttatca atttattcac
     3541 agatgttcct gaaattacgg caaagatcaa aagaagacgc tatttggatc ctatattgac
     3601 tcatattaaa agagaatcaa aaaacactta tctttacttg tttgcaagaa gattggcaag
     3661 aggttctgat tttagtggtc tttatttccg attagtaatt ataggtgggt tattgattgc
     3721 cggagtagtc gacttttatt ttagtctgat tatcggtttc ttatttttat atttgatcgg
     3781 tttccaactg ttacctttag cgaaccagtt ccgctatatg gttctcgttc agctttatcc
     3841 aatccataag aatcagaaga agcaggcgat tcagtatcta ctcacatggg tattaattat
     3901 cgcgtcggtt atttttggtt tgattgctgc agtcgtatta gatgggcagc agcgatgggt
     3961 tccgctagcg gcttatttga ttgttactat gctctttgtt aaactatatg taccaactcg
     4021 tttgaagaag atgtcagact gaaaacaaag ctgtgtaggg taaaaatgag aatgaaaaat
     4081 agagcgttga cagtaagaat gctgttcgtt ctattttttt tgagaaaagc tggttttttg
     4141 aatggcaatt aaatgaaaaa gaacgtatat gtgcttgacg tgtagtgttc aggcgactag
     4201 aataataagt actgcaaaac aaagagtaag aggacgggag aatgcatgat ggagtttcag
     4261 ttagaccaag agtggcggtt acgtcccatc aaaggcgaca caggaaaaac atacataggc
     4321 atgcgtgatg aggacaaagt ctttattaaa cgaaacacga ctccgatgtt ggctgctctt
     4381 tcaagggaag gaattacacc aaaacttgtt tggacaaaac gaacggggaa tggcgatact
     4441 ttgacagcac aagagtggct ggaaggtcgc ttgctgactc ctaatgagat tggtcaaaga
     4501 aacgacgtga ttgatgtttt gtaccattta catcattcaa attctcttaa aaccatgctg
     4561 acccgtatcg gtggtcgtgt catgacgccg gagaagatgc tgcaaaaata tgaaaaagaa
     4621 ttaccggaag aactccagaa aaatcaattt ctgcaaattg tccatcgttt tcttcgtgag
     4681 cagatcccgt caatagataa ggaaaactta tcagtagtac acggagatgt aaaccatcgt
     4741 aattggttag tatgtaaaaa ttatttatat ctagtcgatt gggattcaat catgtttgca
     4801 gaccctgcgg tggatattgc aacgatttta ggaaattatg tgccactgtc tagctggaat
     4861 cagtggctga tcagttatgg catacgcccg actgacgaaa tgcttgaaaa atttcattgg
     4921 tatgcggcca tgaatttgct ccaagaaatc accagatatt gcaaacgtga agatcatcga
     4981 cggatgaacg aagaaatttt acaattaaaa cgaattttca gtggctgagg tttggcccaa
     5041 actctgcgga gatttggcca gaccttttta attagaggaa aggaatggag ataaataatg
     5101 cgtgtccgaa atcgtccggg agcagcggaa atgttagcgg ctcacccgaa ttttgtaatt
     5161 agtgatccaa cattgtggaa gggaaaatgg aatgaattgt ttgaaaacga tcatccaatc
     5221 cacattgaga ttggtatggg gaaaggccag ttcatcactg gaatggcaaa agcccatcct
     5281 gaaatcaatt atattggagt agaaatgcag gtcagtgttg tttcgattgc actagacaag
     5341 ttgatcgaac aaccgcttcc taacctgaaa cttctacatg tggatggatc agcgttgaca
     5401 gagtatttcg ctgacagcga agtagatcaa atctatctga atttttccga tccatggcca
     5461 aaaaaacgtc atgaaaaacg gcgattgaca tataagactt ttcttgctgt agatgaacag
     5521 attcttcgtc caaatggaga aatccatttc aaaacagata atcaaggatt gtttgagtat
     5581 tctctggcaa gtttttctca atatggcatg atcctcaaac aggtatggtt agatttacat
     5641 caaagtcaat ttgaaggcaa tattatgacg gagtatgaag aaaaattttc ttcaaaaggt
     5701 caacgtattt atcgagtaga agctcaattt caagataaga ccaaaaagaa aagtctgtga
     5761 aactaacttt ctgctttcat aaaaacatta atatccataa ataaatccca gaaaatgaac
     5821 attacagatg taatgtattt tctgggattt atttgattta aaatgtattt atttcatcgg
     5881 tttttccaca aggtggaatc aattggaagc gagaaaatga aaataatcct ttgtcggtga
     5941 tcttcaattc gggtatgaca gataatgtta agaaagaaag tgtcaaaaaa ggatcaaagg
     6001 ttttagctgc tcctagttga tgtgctttag ttattaattc attcaactgt tcatagacga
     6061 tcgaaaaagg ttcctgtgtc atgattccgc ctataggaag agaaacacaa gctatttcct
     6121 gctgattgtt gacaacggtc atcccgccac ctttttgaat caaaagatta gcagcataca
     6181 gcatatcctc gtcgtttgtc ccaacgacaa ctagattatg cgagtcatgg gcaatcgttg
     6241 tcgctatcgc tccttgtttc agctgaaatc ctttcactat gcctaatcca atgtttcccg
     6301 tttgatggtg acgctcgatc accgcaatct ttaattggtc tttttcgatt gaaggaatga
     6361 atcgttcgcc ttgtcggtcc actttttcta ccaaatcttt agtcactaga ctattcggga
     6421 taatttcgat cacatgggct tgtgaagaag aaagaagcag ctctaacgaa tgtggattta
     6481 atggttgagc gtttagtttt ggcagacaac acgtatatga atttgaatga tcagcaaata
     6541 aatggtcttg gagttgccca gattgaacaa ctaatgttcc cttatagaaa acttcatgaa
     6601 ttggcagctt ggtaagatcg tctgttaaga agaaatcagc ttgataccca ggggcaatcg
     6661 cacctagtgt tttcaaatca aaacattctg ctgcattcaa tgttgccatc tgaatggctt
     6721 gtaatggatc gattccaagt gcaatagctt gacggacgat atgatcgatt gatccttctt
     6781 ttactaaatc attgatcagt ttatcatcgg tgacaaagaa gcatcttctt gaattttcag
     6841 gtgtgatcgc cggtagtagc gatgccagat cttttgcaac ggtcccttct cgaaccatta
     6901 aatacatacc aagatccaaa cgttctttag cttcttttgc agttgtagct tcatgatccg
     6961 tccgaatacc tgctgcagga taaacattta actcttccat gccgatacca gctgcatgcc
     7021 cgtcaatttt tttcttatgc tggtgcatca attggatctt ttctaggatg tctgtttcat
     7081 tatttgctac tgcttgatag ttcatgactt cagctaagcc taaaacttcg ggtttttgta
     7141 aaaaaggggc taattttttt gcatttaaat ttgcaccatt ggtctcaaaa ggggttacag
     7201 gtacacaaga aggtagcata aaaaagatat tcatgagtgt ttgtcttgca tcttctatca
     7261 taaactcaag acctgtactc ccagcaatgt ttcctatttc atggggatct gtcactacag
     7321 tagtaactcc atgaagcaag gatacttttg aaaattcgct tggtgataaa agtgagcttt
     7381 cgatatgcac atggccatcg atgaatcctg gcactagata ttgcccatta gcattatgta
     7441 cgctttttcc ttcgtattca ccgattccta cgatcattcc ttcgcagatt gctacatctt
     7501 tttccatgat ttctttcgta aagacgttga cgatcttagc atgcttgatc actaggtcag
     7561 caggcttttt tttacttgct acttcgatat atttccttaa tgttgtttcc aatggagtgc
     7621 ctcccaagat aaatttttat aagtataaca taaattcggt ttttgccaat atttttttgt
     7681 aaattcattt tatttgaaac aaaaagatca aaaagacgta tgttttttgt ggaggggaga
     7741 ataatggaaa taaaacgatt atcggatcaa atgataagtg aaagttttgc caaacatgcc
     7801 caagacgtat atatattgcc agcttcagaa gtattttaca tctattttcg ctatggaaaa
     7861 aaacgaacat tctggaagaa agtctcttcg gcagatggac agcaactgat ctcaagattt
     7921 aagtatttgg gacagatgga tatcggagaa aaaagaaaag ctcagttagg tgcatttact
     7981 tattctttag aaaaacagga agttcgtctg cggttgtctt ctgtaggaga ttaccttcaa
     8041 cgagagagtt tagtgattcg gctattatac ggtacttttg aaacacccca tcgttgcttt
     8101 agttctcgag attttgcaac tattttacag aaaaccgtca gacgtggatt ataccttttc
     8161 agcggaccag tcggatcagg caagacttct ctaatgtatc ggttggcttt ggaagaaaaa
     8221 ttgcaagtga ttactatcga agatcctgta gagatagaag aaccgttttt tctgcagcta
     8281 cagatcaatc cgaaaatagc acagacttat gatacacttt tgagactcgc attacggcat
     8341 cgtccagact tgctaatcat tggcgagata agagatgaat caactgcaca tgctgcggta
     8401 agagcagcac taacagggca ccgggttttt gcaaccgtac atgcacgcaa tcttgaaggt
     8461 acattggtca gaatccatga actgacaaag aaaaaagaag agctatctga atgtttagct
     8521 ggtgtcattt atcaagaact tttggaagat gccaatcacc atccttctgt tttatggagt
     8581 tatcaattta tggaggaaga atcagtaaaa aaatcatggg aggaaagtta tgaagaagct
     8641 caggaaaata tttggcagtc agaactattc taaaggatta acaagaagcc agcaaaacca
     8701 gtttgcacaa accatgggag aactgctttt atctggtttt agtctgcaag aatcccttta
     8761 tttattactc acgatccgtt cgtttccacc tgttattttg gcaaatatcc aacatcagct
     8821 aaaggaaggg caagcgttta gtgaggtact ttcgcaaata ggatatggag cagagcaact
     8881 ggtacagatc gagttagctg aacgtcatgg gaatctgccg acaactttgt tggaaattgc
     8941 caaacagttt cggcttgttg aaggatttcg caatgatttg aaaaagctgc ttgcatatcc
     9001 gatgctattg ctcacctttt tgctaggtat cttgtttagt atgcggttgt tcgttttgcc
     9061 tcagcttatt ggttcaggaa tggtcatgca agagcattgg ggtattcagc tgatacaagt
     9121 ctttcattgg tatgttctac tattcatcct agcggttact ctattggctt tactagtaag
     9181 gtatcgtctg atgaagttgt ctcctgttga tcagagtgaa tggataagca gacaattatt
     9241 gattggaccg atatattcct tgtatcaatc ggcttatttg tcactagaga ttggaaagct
     9301 ttttcatgaa ggtttcgaat taaggcaaat catagtctgc ttaaaggaaa cgaaacaaga
     9361 aagtctgatt cagcatcttg cctctaagtt gattcaagga ttggaggcag gtatgtcatt
     9421 ggctgagcag ttccagaatt atcgttttct atcagaagaa ttcagtaaaa ttgttttaca
     9481 gggagaggca aagggaagtt taggtaaaga actgattttt tacagcgaat ggacaagaaa
     9541 acagcttttc aaacgtcttc atcactggat gcattttatt cagccaatca tttttttggg
     9601 cgtagcggct ttgattttat tagtttatgc cgctgtttta ttacctgttt acggaagcat
     9661 agaggaggtt ttgccatgaa aaagagaaaa atatcttatt atagcggttt tacattgatc
     9721 gaaatgctaa tcgtcttact gatcatcagt gtattagtgt tgttgttcgt ccctaatttg
     9781 tcgcgttata ggaatcatgt agaccaagaa agtcgtgaag cgatcatcca gttggtagac
     9841 acacaaaaag agctctatgc gcttcaaaat aatggaagag ttcctactgt ggaggaattg
     9901 ttgaatgaag gctatatcaa acgagaacat gcagaaatct atcagcggcc ttgaaggtaa
     9961 ggttttagca tcaggatata cgttgtttga atcactctta ctgattttat tacttacaac
    10021 gatcctttct tttccagttc tcgcattttc tgcatggaag aatgaattgg cagtctatca
    10081 atttttcggc caatttgaaa aacgaatcta ttctacgcaa aaaatcgcta ttgtgaatca
    10141 gatccaaaca ggcttttatt ggaatagtga agagaatcaa atcatttttc atgttccgaa
    10201 tccagataaa ataaattggg aagtattaga tattcctgat gagattacct tgaaacgcca
    10261 tgcttctatt acttttgctg ctagaaccgg gaatgaaagt tcactaaaag cttatcaatt
    10321 ttattgggaa gaaaaagagc ggacgattac gtatcaattc cagataggga gtggtcgcta
    10381 tacaaaaaga attgaataaa acaggatttg ttttgttgga gtcccttaca gcgcttatga
    10441 tcgcttctgt ctgtgtctac ttagtgagct ttggccagct gtttttgctt caggcagaaa
    10501 agaaaagtgg ggaggaactg ctatttattc gaatgattta tgaagatatc aagacgcagc
    10561 ggatgtatca caaaagacca gagcgaaggg aagaaatgat cccatacgat atccaaattg
    10621 tcgataataa tggagtaatc gaaaaagtgt ttgtcaatat ggagaaagaa gcgatcagta
    10681 ttgaaaaaac aagtaattcc agcatttacg ctgattgaat gtctaattgg actgatgata
    10741 ttgagcagtc tattgctcac attcaatctt ttgattcagc aaaccatcca agtaagtgaa
    10801 tttttgcagc gtaaagatca aaaagagtgg ctaatatttt tagcacaatt agaagaagaa
    10861 ctcaagagca gtcacaatgt ctctgtgaaa aatcagcaac tgcactacac gatcgaggat
    10921 aaacagtata tcatcgaaag atatcaggca atgatacgta aaagaagaac ttccggcgga
    10981 catcaaccta tgttaacaag tatcactgag cttcaattat tggaaaaaga acacacaatt
    11041 tctttttatg tacactttga aaatggagaa gatggatatg ccatatggac aaaaaacgat
    11101 cagtagaaaa tgttataagg gctctatttt attttctgtc ttgcttttat ttcttttatg
    11161 tacgttttta ttgatggcag cattagaaag ctaccgtttg tcaatggatc ttaatatacg
    11221 aatcaaaaat tattatatag caaaaataat gaagcagatg gctttatcgg aacagtctac
    11281 gcttgccgaa agttcggaag gagtttttta ctacacaact ggatctgtaa catatcagtg
    11341 ggtacaacag tccctattct tagaggtgga agtctcaccg tttatctttc ggttcacaga
    11401 agaagtaaaa aatgatacag atactagtac agaatgatgg aatgttcgtg aaaacgccct
    11461 cttttctgtt ataacactgt ttttaataaa aaaatgtttg ccgtttcaca aataaaaaac
    11521 agtgaaaacg attgaaattt tgtcaattgt tcgatagaat taaacaggtg aaaaaattgt
    11581 tataatatat ctagaaatga ggtgcaccat gttaccagaa aaaatggaac aagggtttaa
    11641 tcaaaacctg gaagctattc agcttttaca gaatgcattg ggaacttcct ttttagaagc
    11701 ctatgtcgaa aatgcagaaa atttaataga tgattatcaa gtacgtgtgg tggatggagt
    11761 gccgacaaaa gagacaacgc aacggatcac agctctttat gaagagttga agaaactttc
    11821 tttcgagcca gaagaatggc gcagactgtc tcaattactt ttattgaagg gcagccagac
    11881 agaacatttg caggcgaacc atcaactcac tcctgatagt atcggttttt tatttgtttt
    11941 tcttattgaa caactataca caaataaaaa agcaccggtt aagattctgg atattgcggc
    12001 aggaatgggc aacttgttat taacagttct tttaaaccta tcgaatgcgg ggtaccaaac
    12061 agaaggaatt ggtgtggata ttgatgatac attgttggct gtcgcagctt ctacaagtga
    12121 tttgacacaa gcaaatgttc aatactttca tcaagacggg ttgcaggaat tattaataga
    12181 tcctgtcgat tttgcaatca gcgatttgcc aatcggttat tatccgaatg acgaaaaagc
    12241 aaaagagttt ttaacaagta ccgaagaagg ccatagttat gcacatcatt tattgctaga
    12301 gcaatcaatg aaatatgtga agccggatgg ttttggtttg tttttgatgc cgagtggatt
    12361 tttagaaacg gatcaaagtg aagaaatcaa aaaatggttt aaagaagaag gttatcttca
    12421 aggaatgatt caattgccag atgaattgtt ccgtaataaa caatcgcaaa aaagtatttt
    12481 gatcttacag aaaaaaggac cacaagcaca acaagtaaaa gaagtcttgc ttgtgaaact
    12541 tgcttcatta aaagaaccag agaaggtgac ggaatttttc aacgagttta aaaactggaa
    12601 atcatctgct ctgtaatcat tcaacgagaa ggagagtcat atgtctaaaa caattgcaat
    12661 caatgctggg agttcaagtt tgaaatggca attatatcaa atgccagaag aaaccgtagt
    12721 tgcgaaaggg atcgtcgaac gtatcggttt acaagattct atttttacca tcaagtacgg
    12781 cgataatcaa aaattcgaac aaatcatgga tatcgaaaac cacgaagtag cagtaaaaat
    12841 gctgttagat cagttgattg aactgcaaat tttaagctct tatgatgaaa tcaccggagt
    12901 agggcaccgt gttgttcacg gaggagaaac ttatggggat tcagtagtga tcgatgagaa
    12961 agtaatggac cgcattgctg aattagcaga atttgctcct ttgcataatc ctgcaaactt
    13021 aatggggatc aaagcgttta aaaagatttt acctgacatt ttgagtgtgg ctgtattcga
    13081 tacatctttc cactcaacaa tgccaaagca aaattattta tatagcttac cggtgtctta
    13141 ttatgaagat ttcaaagtaa gaaaatatgg cttccatggc acaagtcatc gttatgtgtc
    13201 ggaacgtgcg gcaaaattat tgaacaaacc gatcgaagaa ctaaaaatca tcacttgcca
    13261 cttaggaaat ggtgtatcga tcacagcagt cgatggaggt aaatccatgg atacttctat
    13321 gggattcaca ccattagctg gggtgacaat gggtacacgt tcaggtgata tcgatccagc
    13381 tgttctccca tatttaatgg aaaaattaga gattgatatt gatgaaatga tcaatgtttt
    13441 gaacaagaaa tctggtctgc taggcctaac aggattgtct agtgatatgc gtgatcttga
    13501 aaagaactat gaaaaagaac atattcgttt agcttatgac attttcgtgg accgcatccg
    13561 aaaatacatc ggcggttatg tgacaacgat gaatggtgtt gatgcaattg tctttactgc
    13621 tggtatcggc gagaatgacg gacatgtacg tagtgaaatc atcaaaggta tgtcttggtt
    13681 tggttgtgaa atcgatccag cgttgaatga attgcgtggt gaagaagtag atatctctac
    13741 aaaagaatca aaagtaagag tattagtgat cccaacagat gaggaactaa tgattgcccg
    13801 tgatgtggag cgtctgcgcg gctaagccaa agcattcgtt aggataaaag atgaaacgca
    13861 tgcaagaggg aattcttgca tgtgtttttt ttgcggagaa gaccgcaaaa tggtaattta
    13921 acttcaattt cccttctttt ttacaggatc ttcttaggga attttgcttg gaaaagtggt
    13981 caaaagggaa aagactggca ttttatttat tgattttcag gaaaatccca atattttatt
    14041 ttcattcatc tttataaggg acattacata tgtaaaaaga aaaaacattt ttagatcagc
    14101 ctcgtgggct gtcgacttta ttcttcgctt tatgtttagc tagaaaaccg atccgaaaca
    14161 ttcattgatc gaataataaa aacttgattt tccacctgta ctttgcctga atcgtgaaag
    14221 cacaggtatg aaaatcaagt tttttgttgc gaaaaaacgt cctagtcaat cagttggccg
    14281 agcggctggc ggctgatctg ctcctgatca ataacgagtg cttcttggaa gtgttgctgc
    14341 aaaaagtagc ggtcatggct gactgctagg agcgttcctt gatagtcttg cagcatttct
    14401 tcaatttctt ctcgagcata gctgtcgagg tgattggttg gttcatccaa aatcaggacg
    14461 ttgatttttt ctaaaaagag tttcagcaac gccaaacgga ttttttcacc accggataaa
    14521 tctttgatcc gtttacccac atcgctttga taaaagccac ttttggctaa ttgccgtcga
    14581 gcgacttctt cgtttccagt caatgtgatg gcgtaagcca gcaaacggct atcgggatcg
    14641 gcaaactgca gctgctgcgg caaataaccg atttgcaagc tactacctaa tttgatggtg
    14701 ccaccgtaag gcttttcctc accgagtaat aatttgagta aggttgattt tcctgcacca
    14761 ttgtcgccga tgatggctaa atgatctcca cgatagactg caaaactgct gtctttgaat
    14821 agtacttgat cagcgtactg ctggtgcaag ttttgaatga tgaaaacttc tttgccagat
    14881 tttccaccat tagacaagct ttgcagccga tttttcgggg gaggtggcgg tttgacgagt
    14941 gtcagtttcg ccaggcggcg ttccagttct ttggcttttt tgaagaagga ctcattgtct
    15001 ccttcatgtg cccactgacg aaaacgacga atcatgactt tcaaccgctg gacttctttt
    15061 tgctgcagtt cgtaattttt tgtcagctca gccaagcgag cttctttcaa gactcgaaaa
    15121 cggctgtagt ttccgggata ctcaatcaat gcaccttctt ccagttccca tgtttttgtg
    15181 gtgacttgat cgagaaattg ccgatcatga gaaacgacca gaaccgattt ttttgtattc
    15241 tgtaaatagt tttccaacca gcgaatactg ttaagatcta aatgattggt cggttcatcg
    15301 agtaaaagta aatcggcatc ggctgctaaa attttggcta aagcgacttt aactcgttcg
    15361 cctccgctaa gttctgttaa ccgtgcttcc tgacggtgtg gaatccctaa gccttgcaag
    15421 atcgctgcaa tccggtcttc taatacgtaa ccgcctagtt cttcaaagcg atgctgcagc
    15481 tcaccgtaac gggccagaca cttctctaag tttgtatctg gttctgtcat caatgcttcg
    15541 tagcgactca tttgctgttt gaggtcctgt atctcagcgg cagaatggag caagtagtgg
    15601 ttgacggtcg cttcggaaac tgtaagttct tgttcgaccg tcccgatctt taagcctttt
    15661 ttgcgactga taacaccgct gtcgacacct tctctgccgg tcaagatttg taaaaaggtt
    15721 gatttgccag ttccgttgat accgactaag acaatttttt caccagcttc aatttgacag
    15781 gataaatcct caaataatgg attcccgccg attgtttttt taatagaaat tgcttgtatg
    15841 atcatgatct ctctccttga gaccactcaa aaaggccatg gttatccatg gcctgtgtta
    15901 tttaaactca gattatcatg agaaaaatac cttgagatgg ccattgattt tacgtgaatt
    15961 caactgtttt ggacaaactt gtcccgtcaa cagcaactgt aaaaccaatt gcatggctaa
    16021 atgcgatatg gtatcgttgg taattttcat tacttgttat tttagtcatg cgcatcatag
    16081 tattttccct ccttcgtgta gttgtctttt ccagtgtacc tgaaagtgtc agaaagttca
    16141 actagcgctg acatttactt aatatttatc gatgtgtaat tctgtcagag agcttttttt
    16201 atctgactga gggtaatgtc tcgtggacca catcattgta ttctgagcta aaccagcgtt
    16261 caggcgaaat catatggtgt ttgataaaaa actttgtcta catgacttcc ttttgccatt
    16321 tgcttaatac cgttgcatta aacagctctt ctctttggaa atctcaccaa catcgcgttc
    16381 aggagtatcg ttgtggttgc aatggcaagc ggtagccttt catcaattct tgaatgattt
    16441 accgaatgta gcacttgcct tctcgcggta cccgaacccg aaataaaatt ttagtttggc
    16501 gataaaatcg gtatccgcca tcgatacttc atattttttc gtatcagatt catcggaaac
    16561 ttccacattg acgaaccaat aagctttggc atgcttaggt cgttttaaac cacaccaggg
    16621 cgactaatcg ccctggtgtt cacttttttt tattttactt gaactcattg actgttttcc
    16681 ctttatttta aacattataa agaccgatga gtgcttgccg cgtcttttgt ttttatcacg
    16741 gttttttgtg caaaaaaacc tgccgatagt tggcaggtcg tctacgtgtt aagctttggt
    16801 gtggtcttta gctggcaatt ggttttctaa atcagttcgg acaacaagca catcgcaagc
    16861 tgcgtttcta ataacatatt cagaaacaga accaataaat aaacgttcta cagcattcaa
    16921 tcctgtggct cctaacataa tcaaatctac ttgattatct tctgggattt ctctggcaat
    16981 aatttgtttt ggtgagccat attctacgac agaggttaca ttattcaagc cagctttctt
    17041 cgcattgctt tcataatctg ccaatgtttg ctttgccatt tcagtagctt gttctgcaag
    17101 cattccatca aaggatgaaa cggtttggaa agaacgtgtg tcaatgacat gtgctaatag
    17161 aagttctccg ttatttcgga tagctacatt gaccgccttt ttaaaagcta attcagcttc
    17221 atcagaacca tctacggcaa ccatgatttt tttgtattgt tgtaacataa gcattcactc
    17281 ctcaagtcaa tcgtattgta ctcttttatt gtagaacact ttagggaaaa agagaattat
    17341 ttactgcttt ggttcagcaa ttttttttgc aaatcggata ctgaaggtgg cagaaacaat
    17401 aattacgatc agtaaaaaga ccaaggcaat aaagcgttga ttgaaaaaag ctgttaaaat
    17461 acccattacg cctaaaacag catatgcagc tccgtaaaat tgtaggaatc cttgattttt
    17521 atcatttttg ttgatcaata caaaaaagat atcctgttta ttaaataaat aatagctaac
    17581 gaataataat actaaagtgg cgataatcat taaaatccta atcatgaaca aatcctccaa
    17641 aataagcaac aaatagaaaa agcaatttgc caagagcaaa ttgctttatt ctttaaaaga
    17701 tggtaatctc cgttaatgcc gttgtttgtc ctgtagtatt gatcccgcga attcaagcag
    17761 gtgggtccca tggtcgtagc ttcgaactac caaatgataa ggcatgttac cagcagtgac
    17821 acaagacggg tcccaagata tcaataaaaa tgttcggtca acacacaaag aggacaattc
    17881 gaacatcaca gatttcccac ctctatagta gcatatgaat ttaaaaagag caatgagaga
    17941 gctcgcagaa acagaaccgt tttcttgtct agttttttgg aggatgcttt ttccactctt
    18001 ttatacggta atactgttga cccagagcct gttcatattt ccccgtatct tttggctgat
    18061 aatactgagc attcttcagt ttatctggta aatattgctg attgacccaa gcctgatcaa
    18121 aatgatgagg atactgataa cccacgccac ggttgagtga tttcgcacct ttgtaatggc
    18181 tatctctcaa atgatcagga acatctccag ctttgccctc tcgaatatca gcaagtgctg
    18241 catctaatgc catgtaggca gaattggatt ttggcgacaa gcaaagatcg acgacgacgt
    18301 ctgctagtgg gatacgtgcc tcaggcaatc ccaatttttc agcagctaat acagcgttca
    18361 ctgtacgagc cgcagcagca ggattaccta aacctatatc ttcataaccg ataaccatca
    18421 gacgccggca aatacttgcc agatcacctg cctcaactaa acgggcgaga taatgaagtg
    18481 cagcatccac atcacttcca cgaatcgatt tttgaaaagc cgaaataacg tcataatgag
    18541 catctccatt tttgtcatgg gtaagagctt ttctttggac acattcttca atgatcgaca
    18601 gtgtaagatg aatccttcct tctttatctg aaggagtcga tagtgtagcc agttccagcc
    18661 cattcaatgc actccgcaaa tcgccgttcg ttgcacgcga aaggtgaaga agagcatctt
    18721 cgtctaactg gattgcttgt tgtccaaggc cgcgttcttt atcccttaaa gcatgttcga
    18781 ctgccaactg gatgtcttgt tctgttaatg gtttgacttc aaagatctgt gtacggctgc
    18841 ggatcgctgg attgatggta atataaggat tctcagtagt cgctccgatc aagatgattc
    18901 ggccactttc taaatgagga agcagaaaat cctgttttgt tttatctaat cggtgtactt
    18961 catccaataa gaggatcact gtaccactca tttttgcttc ttccgctaca acttgtagat
    19021 ccttttttga atctgtagcg gcgtttagca tgcgaaatgc ataattagta gagccggcga
    19081 tcgcacttgc gatactcgtt tttccagtac caggaggtcc atatagaatc atggaagaga
    19141 gcatgcgagc atcgaccatg cggcgtatga tttttccttc cccgactaga tgctgctgac
    19201 caacgacttc atcgatcgtt cgaggtctca tgcgataagc caatggctgt tgcataggat
    19261 tttcctcctt cttgttttta cgtcccttaa ttatatcata tttagcaaga tgcctagaaa
    19321 gaacagcctt ctgttgtttt gttttcatag cttatccaac taatattgtg tatgataaag
    19381 taggtgagaa aaatgacgga taaacaaaag atagatgaat ttttttggaa taaaacgacg
    19441 ccagaagtgg cacgggattt attggggatg tatttggagc atgacacacc agaaggaaga
    19501 ttagctggat atattgtaga cgcggaagca tacctaggtc cagaagacga ggccgcccat
    19561 agctatggtt taagaagaac accgcgtgtg cgggcaatgt atgaaaaacc aggtacgatc
    19621 tacctttaca cgatgcatac tcatcggatt ttgaacatca ttactcagcc agaagggatt
    19681 cctcaaggag taatgatacg tgcaatcgaa cccgccgcaa tgattgatca aatgagtaaa
    19741 aatcgtggcg gaaaaactgg tccagatatc agcaacggtc cgggaaaatt agtggaagca
    19801 ttagcaattc ctcaagaact ttatggtcag tctatagcag atagttcgtt acgcttagtt
    19861 tttgagaaaa aaaagacacc aaaaaagatc aatgctttgc ctagaatcgg tatcccaaac
    19921 aaaggtgtat ggacagaaaa gccgttgcgt tttgttgtgt cgggaaatcc ttatatctct
    19981 ttacaaagaa aaaaccaaat cgagaaagat tggggttgga ggaaagaaaa tgaaaaagaa
    20041 ggatctatta acatatttag atgaaataat tgaaaaacaa gtgacagact atgatgtagc
    20101 tttagattgg gatacaaaaa atcatacgat cgagatcgtt gttcgcttgt ttgcagaaaa
    20161 taaagcacaa tttgagattg atgatgcaga agggatcgtt tcgcaagaac caattatcga
    20221 atttgaagac ggcgtacttc tttttaatcc tcagaaatct gtttttgatg aacgcaatta
    20281 tctagcagta atcccttatg aaggaaaaaa agggttggca aaatcagtag ctgattcttt
    20341 agtggaatat ctaaatgaag tattagctca agggcaaagc gatttgcttg attttttgga
    20401 tgaagacgat gacgaagctg tattcgagct tcactgggat aatcagcaac tagcagaatt
    20461 agtagaagta aaacagcaaa atgaagcaga tacttattta ccgtacccaa gttattaagg
    20521 agtgacagat atgaaatgga atgaagtaaa agtagaaact gaaagtgaag cagtcgaagc
    20581 agttgctaat attttgatgg aggcaggggc gagtggtgtc gcgattgaag attctttaga
    20641 tgttgaacat tttcagtcgg atcaatatgg tgagatttta gataaaaatg attttacatc
    20701 gctgaaagaa ggcgcactag tcatggctta ttttccggaa acgactttct taccggaaat
    20761 cttgcctttt atcaaagatc gtatcacaca attacctgag tttggtctag ctattggaaa
    20821 aaataaagta acagttagtg aagtagagga aagcaactgg gcaacagcct ggaagaaata
    20881 ctatcatccg gtgcgtatta cgcgaatgct gacggttgcg ccaagctggg aaaactacca
    20941 gacagaagat cctctagaaa aaattatcac actagatcct ggtatggcat ttggcacagg
    21001 cactcatccc acgacttcct tgacattgac agcactagaa acagtcttgc gtggtggtga
    21061 aacattgcta gatgtgggaa ctgggtcggg cgtgctaagt attgcagcaa aatatcttgg
    21121 tgcaaaagat gtctatgcct ttgatttaga cgaagtagcc gttcgttcgg cgaaagaaaa
    21181 tatggatatg aatgaaatag ccaaagatgt ccatgtatca gctaacgatc ttttgacagg
    21241 aatcgagatt gaaagtgatg taatcgttgc gaacatttta gcagatatca tcttattgat
    21301 gatcccagat gcttggcgtt tactgaagca aacaggcacg ctgatcgttt caggaatcat
    21361 tgaagagaag aagcaaatgg ttctggatgc catgttagaa caagggttta tcgtggatca
    21421 aattttccag caaaaagact ggtatgcaat tattttgaaa aaaccagagg tggaatagat
    21481 gcagcggtat tttttaaaag aatcatatga atcaaaagac tattttgttt tagaagggga
    21541 aaactatcac cacattgtac gggttatgag gatggaaccc gaggatgaag tttttttggc
    21601 attcaatgat caaatagcca ttgttgcaga aatcacggag attactgaag aggctgttta
    21661 tctgaaagaa attaaaaaag aagaaaatca aaaggaactg ccaagttcga ttaccatagc
    21721 gagtggctat cctaaagggg aaaagctgga ttggatcgtt cagaaatcca ctgaattagg
    21781 agcgcaagct tttcttggtt tcccggcatc agcctctgtc gttaaatggg atgcaaaaaa
    21841 acgtatgaaa cgacaacaac ggcttgaaaa gattgctcaa gaggcagcgg aacaatccca
    21901 tcggcagatc gtgccatcag tagagttatt ggaaacgaaa caagatttat ttgagcggct
    21961 agatgattat gacgtggtct tggttgctta tgaggaatca gcaaagcaag gcgaaaaatc
    22021 aaatgcagcc aaaattctta gtgaaacaaa accagatagt cgaatcttag ctgtctttgg
    22081 accagaaggt ggattatccc gcgatgaagt cgattatttt gtagaacaca aagggatact
    22141 ttgtggatta ggaccaagaa tccttcgtac agaaacagca cctctttatt tattaagtgc
    22201 tgctagctat caatgggaat taatgaatcc ttctttcagc taacgttctt cattaataaa
    22261 agagtatcga cagaaagaat tgaaaaaata gtcaacaatt tgtataatag aaacaattat
    22321 ttatacaatg gatacgaaaa atcgtttgaa aaagctttta aaaagcgaac atttccgtaa
    22381 aaaaacgtat aactgcacgg attttgggac aattatcaaa cagatatttg tcccgattcc
    22441 cgttttaccg aaaaaagaaa gggggatcga ttcctgtgac aaaagaagaa attttaacgg
    22501 gacccggtgt cataaagctc gttagtcaat acatgggtcc cgaacatgta gcatttgttg
    22561 agaaagcatg cgaatacgcg actgctgcac atgacggaca gtttagaaaa tcaggcgaac
    22621 cctacattat tcatcctatc caagtcgcag gtatattagc agatttaaaa atggatcccc
    22681 atacagtggc tacaggcttc ttacatgatg ttgttgaaga tacagaaatc actttagaag
    22741 atctgagaga agaatttggc gatgacgttg ctatgttagt ggacggcgta accaaattag
    22801 ggaaaataaa atataaatcc cacgaagagc agctagcaga aaaccaccga aagatgctgc
    22861 tagcaatggc tcaagattta cgagttatca tggtcaaatt agctgataga ctacataaca
    22921 tgcgtacgtt gaagcacctg cgagaagata agcaaagaag gatcgctcag gaaactttag
    22981 aaatctatgc gcctcttgca catcgtctag ggatcagccg gatcaaatgg gaattagaag
    23041 atacagcact tcgttatcta aatccaaaac agtattaccg tatcgtccac ttgatgcaga
    23101 cgaagagaga agaacgtgaa aaatacgtaa gtggtactgt tgaagatatt cgaatagcga
    23161 cagaagagct ggggattttt gcagaaatct atggacggcc aaaacacatt tattcaatct
    23221 atcgtaaaat gaaagatcag aaaaagcagt tcaacgaaat ttatgacttg ctagctattc
    23281 gagtgatcgt agattcaatc aaggattgtt atgctgtatt aggagcaatc cacacaaaat
    23341 ggaaaccaat gcccggcaga tttaaggatt atattgccat gccaaaagct aatatgtacc
    23401 aatctttgca tactaccgtg atcggtccgg caggaaatcc ggtagaaatt caaatccgaa
    23461 cacaggaaat gcatgaaatc gctgaattcg gggttgctgc acactgggcc tataaagaag
    23521 gaaaaaatga aaaagtagaa ccagatggta tgacgaaaca attaagctgg ttccatgaga
    23581 tactcgaact tcaagacgaa agctatgatg cttctgaatt tatggaaggc gtaaaaggag
    23641 atatctttag tgataaagtc tacgtcttca caccaaaagg agacgttact gagttaccaa
    23701 aaggatccgg accattggac tttgcataca gtatccatac agatatcggt aacaaaacca
    23761 ctggtgcaaa agtaaatggc aaaatggtgc agcttgatta caaattgaaa aacggagata
    23821 tcattgagat catgacttct ccaaattcat ttggcccaag tcgcgactgg ttgaaattag
    23881 ttgctactag caaagcaaga aataagatca aacgtttctt caaagcccaa gatcgagaag
    23941 aaaatgtgat caaaggccac gaatccgtgg tcaaatgtat tacagatcta ggatttacgc
    24001 ctaaagatat tttgacgaag aacaaactgc aagaagcact cgatcgtttt aattatcaaa
    24061 cagaagatga tctctatgca gctgtagggt atggagaagt tagccccttg acgatggcca
    24121 atcgtctgac tgaaaaagaa cgtaaagaac aaaaaatcga gcagcaaaag caagaagcag
    24181 aagaaatcat gaatcagccg aaaaaagaac ctgacaaaat gaaagtacgt catgaaggtg
    24241 gcgttgtcat tcaaggggta gaaaacttac taattcgtat cagtcgctgc tgtaatccga
    24301 ttcctggtga tgatatcgtt ggttatatca ctaaaggcag agggatatcc attcatcgtc
    24361 gagattgtcc gaatgttcag cctgacaaac caaatgtagc agaacgtttg attgaagtcg
    24421 aatgggaaga tacatcgaat acacgaaaag agtatgatgc agatttggaa atttacggct
    24481 ataatcgttc aggcttattg aatgatgtac ttcaaacagt caatgcgcta acgaaaaatc
    24541 tcaacagcgt tgaagcacgg acgaataaag ataaaatggc gacgatccat ttgacggttg
    24601 gtatccagaa tttatcccac ctaaagagta tcgtggataa aatcaaagca gtacctgatg
    24661 tctacagtgt acgccggacg aatggatagg aggacagata tgagagcagt tgttcaacgg
    24721 gtaagtaaag ctgctgtgtc agtcgatcag caagaaattg gaaaaattgg ctacggccta
    24781 cttgttttat taggcattca tgaaaccgat acgcaaaaag atgtggacta tctggtaaaa
    24841 aaaattgcac aaatgcgtat ttttgaagat gaacaaggaa aaatgaatat tagtgtagaa
    24901 gatgtgggag gacaaatttt aagtatctct caattcacac tgtttgcgga tacgaaaaaa
    24961 ggaaatcgac caagctttgt ggaagccgca cgaccagaaa cagctattcc tttatacgaa
    25021 tcattcaatg aaggaatcag aagtcgcggc atcacagtcg ctaccggaca attcggagca
    25081 gatatgtcgg tttctctcgt caatgatgga cctgtaacga tcattattga ttctaaaaac
    25141 aaataaagta atctggtttt cactagtaaa aactatgaaa cacgtcgctt aagttagact
    25201 gataaactct aacttaagtg gcttttttgt ctgcaaaaag cgcttctttt gtcagcagtc
    25261 ggaaaaaaag ttaagcttaa attatacaag ttatttttta taggaggttg ctgaagatga
    25321 aagaagtacc agtagtagat atcaaaatca cagatttaaa aaaattgtat caaaaaggat
    25381 acaacatgtt ggaggagtta cgccatgaag cggacgctcc cgtcgtcaaa gcaaagattt
    25441 tcaataaaga agctatcacg atctacggat catcagcagc aaaagtattt tatgatccaa
    25501 ggaatttcaa acgaaaaggt gctatgccaa aattagtatt gaagacactt tttggtcaag
    25561 gtggagtaca gactttggat ggagctgctc atcaccatcg gaaaaatatt tttatggatc
    25621 taatgacacc ggaaagaatg gaagattatc atcgtatctt agataagaat ctgacacaag
    25681 cacttgaagc acagcatggt caatttgaac tatttgattt aagtaagatg gttttcttta
    25741 catctatttg cgagtgggca ggtatcaatt tatcagcgat ttctaaagat gaggtcgaaa
    25801 aattagcaga atatcaaatc tctatgatca gcggaacgtt tacttctccg attgatcaca
    25861 taaaaggtgt cgaaaatcgc aaaaaatcag aaaaatgggc gcaaggcttg attgaagaag
    25921 ctcgacaaaa tcctgtggct ggaaaagaaa atgtggcatt atatgctttt gccaatgcca
    25981 cagatttaga tggtcagctt ttacctctgg aagtggcagc tgttgaatta ttgaacatca
    26041 tccgtccaac ggttgctcta actgtgtggg cggcattgat gggacatgca cttttcagta
    26101 gaccagattt gtatcagcaa ttaaaaaatg acttttcgac gttacaagat ccgtttattc
    26161 aagaaatgag acgctattat cctttcttcc caatgctacc tgcgatttcg ctgaaagaag
    26221 tagaagtaga tggttatcgt ataccagaag gcagttgggt tattttagat ttatatggaa
    26281 cagaccatga tgaacgaaca gttgaagcgc cagattcctt tatgatcaaa cggtatgtag
    26341 ggaaagcaaa agatatttcc tataaagaag aatatgagat gattgcacaa ggcgggggaa
    26401 attttcgaca aatgcatcgc tgtgcaggag aatggatcac tcttcatagt ctacgtgtgt
    26461 tttccgatca gctagtaaat aagtttgagt tctctgtacc tgaacaagat tggacgattc
    26521 cattcaatca gtttccgact tatccgaata gccgagcgct actttacaag aattagatta
    26581 gcataaactt atcgaaaaaa aggaagatca aacagtgctg atcttccttt tttcatatta
    26641 ctataaattg ataaggtcaa ttgatcaaaa tccacgaaat gcttcatcaa tggtttgata
    26701 atcttcattg gataaatgca aatctaaagc ttggacattg tcagatactt gctctggacg
    26761 cttagctcca ggtataacta cagacactcg tggattcttc atgtaccaag ctaaaacaag
    26821 ttgcgcagga gtggcttggt atcttttagc aatggggcga agtacatcga cagcggttaa
    26881 aatttctctg aaacgttctc cttggaaatc tggatttctt tttcgaggat ctccttcacc
    26941 aaattgtttt tcctcaccaa gttcatattt tcctgtcagc aaaccggaag caagaggaaa
    27001 atagggaaca aaactgattt tgtttttttc aagataaggg aataattctt tttcagcctg
    27061 ccgatggatc aaactgtatt tatcttctac tacatcgaca tatccatctg cattcgcttc
    27121 tttcaattgt tctaacgtga agtttgacac accgactgct cggatttttc ctgcttcttt
    27181 taattcgtgc aatgtagcaa ctgattcatt ttttggtgtg ctttcatccg gaaagtggat
    27241 ataaaaaatg tcgatgtaat cagtttgcag acgttttagt gcatcttcca ccgattgttt
    27301 gagaaactca ggagaattat caaatgttcg ccctttattt ggtacatgag cagcttttgt
    27361 agcgatgacg acacgtgagc gatcatattc tttttccttc agtacctcgc caatcagttc
    27421 ttcggaacgg ccgtttccgt aagcataagc ggtatcgatc aaattgatcc cgctattcaa
    27481 agctgtacga actacttgtt ttcctgtctc atcttccaaa ccgtcaaaaa gattatgtcc
    27541 tccaacggca tttgctccta atccaagctg ttctgcgtag acttgtgaat gtccgattct
    27601 tatttctgcc atagctgatt cctccttttt gtctagtcta aaacaaaata ccaaaaagct
    27661 gaactaaaac gtttttgtga ggggaaatag tcagatatct cttgactttg agactggttt
    27721 ttagtaggtt ataagtaata tcgaatgtca atgaaagagc gagtaagttt ttgaaacttt
    27781 acaagagagg atcatcgagg ctgaaaatga tctaaagttt cattagccta aagacactct
    27841 ggagatggac gagtgaaaag ccgtcccgcg tacgagcgtt attcgtaaga ggaaagagaa
    27901 atctttcaaa attaggtggt accgtgtatg aatttcattc acccttgttc atgatgaaca
    27961 agggtgattt ttttatttac atagctaaga aagggagaga aaactatgag tttccaaaga
    28021 ccaaaaggaa caaatgatat tttgccaggc gaatcagaaa aatggcagtt tgtcgaagaa
    28081 acagcacgtt tattattcag agattatcag tataatgaaa tgcgtacacc gatttttgaa
    28141 cactatgaag tgatatcccg aagtgtaggg gatacaacgg atatcgtttc aaaagagatg
    28201 tatgattttt atgacaaagg ggaacgccat gtgacgcttc gaccagaagg tacagcacca
    28261 atcgttcgtt cttttgttga gcataaattg ttcggcccag agtatgcgaa accgttcaaa
    28321 actttttata tgggaccaat gtttcgctac gaacgccctc aaaaaggacg gttacgtcaa
    28381 ttccatcaaa tcggagtaga agcatttgga tcagaaaacc ctgcaactga tgtggagagc
    28441 atggtgatgg cacttgattt cttcaaacag ttggggatca cgcaaatccg gctagtcatc
    28501 aattcattag gtgataaaga aacgcgtcaa gcctatcgtc aagcattgat cgactatctt
    28561 ttaccttttg aatcagagct gagtgaagac tctaaacgcc gccttcatga aaatccatta
    28621 cgcgtattgg acagtaaaga caaacgagat caaaaatttg tggcagaagc tccatctatc
    28681 ttagattatc taagcgagcc tgctcaaaaa cattttgata ccgttgtttc catgctggat
    28741 gcattggctg ttccttatga aatcgacagt aatatggttc gcggactaga ttattacaca
    28801 catacgattt ttgaaatcat gagtgacgca ccaaaaatgg gggcacaagc aacgatttgc
    28861 gcaggcggac gttatgacaa tctagtggaa gaactaggtg gtccttcaac acctggcttc
    28921 ggatttgcaa tgggtatcga gcgattactc ttgactatgg aggcagagga agtagttatc
    28981 cctgcattta atgagttgga tgcttacgtg gtcgcactcg gagacgaaac aaatatcgaa
    29041 gcattgaaag tggtccaagc gattcgaaac tttggttttt cagctgaccg cgacttcatg
    29101 aaccgtaaag caaaagcgca atttaagaca gcagataaag cgaatgccaa attagtattg
    29161 gtgatcggtg aagatgagct tgctagtcaa acgattaatg tcaaagcaat ggcaagccga
    29221 aaagaaaaaa gttttccatt agaagagata tatgaacatt ttgatgaagt ctatgatgaa
    29281 atgactttat tcgagtagga ggaaaaaaat aaatggcaca aagaacgatc tattgcggat
    29341 tagtttccga acaacaatta gaacaaacag ttacattaaa aggatgggta caaaaaagac
    29401 gagaccttgg gggagtaatc tttatcgacc tacgtgatcg tgaaggaatc gttcaaatcg
    29461 tctttaatcc tgaaatcaac aaagaagcat gggaaatcgc ggataaatgt cgcagtgaat
    29521 acgtgatcga agtgactggg gaagttagaa gacgcggaga aaatgcagta aatcctaaaa
    29581 tggccactgg tgaattcgaa gtgattgcaa gtgaaatcgt gattttgaat caagcaaaaa
    29641 ccccgccatt tcaaattgaa gatgatcaag caatcagtga cgaaatacgt ttgaaatatc
    29701 gttatttgga tctgcgtcgt ccaaaaatga ctaaaaacat caaattaaga aatgcgacaa
    29761 caaaagcgat tcgtcattat ttagatgata atgactttct cgatatcgaa acaccttacc
    29821 tagggaaatc tacaccagaa ggcgcaagag actacctagt tccttcacgt gtccatgctg
    29881 gacatttcta tgcgttgccg caatctcctc aattgtttaa acaattgctg atgaatgctg
    29941 gattcgaccg ttattatcaa atcgttcgtt gtttccgcga tgaagattta cgtggagacc
    30001 gtcagcctga atttacgcaa gtagatattg aaacaacgtt cttaacagca gaagaaatcc
    30061 aaacttacac agagggattg attgcgaagg taatgaaaga agttcgcggt atcgaagtca
    30121 cattgccatt tcctcgtatg acctatgatg aagcaatggc tcgctacggc agcgacaaac
    30181 cggatacacg ttttgatatg gaattgatcg atctaagcga tacagtcaaa gaagtagaat
    30241 tcaaagtctt ccaaatggct cttgaaaacg gcggtgtcgt gaaagcattg aatgctaaag
    30301 gcgctgcaga tcgctactca cgaaaagaca tggatcagtt aggtcaatat gtaggacaat
    30361 tcggagctaa ggggcttgca tggctgaaag tagaagaaga cggattgaaa ggtccaattg
    30421 ctaaattcat gggagaagca acagaagcaa tcattaaagc aacagatgca aaaccaggtg
    30481 acttgctgat gtttggcgca gataaaagtg aaatcgtcgc tgctgcatta ggtgctatcc
    30541 ggacacgttt aggaaaagaa ttaggactaa ttgatgaatc gaaattcaat ttcttatggg
    30601 taactgattg gccacaattt gaattttcag aagaagaagg tcgatatgtc tctgctcacc
    30661 atccattcac gatgccaaaa gaagaagata tcccgttatt ggctgaagac cctgcaaaag
    30721 tctatgcaga agcttatgat atcgtcttga acggttatga actaggcgga ggttctatcc
    30781 gtattcatac tcgtgagctt caagaaaaag tactagaaac tctaggcttt acaaaagaac
    30841 aaatggaaga acaatttggt ttcttgttaa cagctttaga ttacggattc cctccacatg
    30901 gcggtattgc attaggattg gaccgttttg caatgttatt agccggagaa gataatattc
    30961 gtgaagtcat tgcctttcct aaaaacggaa aagcagcaga tgtgatgagt gatgcaccaa
    31021 gtatggtttc gcctttacaa ttgttcgaat tgaatattga tgtaacgaat atagaagaat
    31081 agccgataaa aaggtaaaaa ggatttgtcg aatacgcttc ttttgacaac cttgatttaa
    31141 ttgaaaaaca ctttataatg aagccataac atataaagcg gggcttttcc atgaaaaaaa
    31201 cattcgaaaa ttgggcttat catgattaca cgaccaagct ttcggtatct atcgtttatg
    31261 cgttgatcgc atcagtcgca ttgaatttct tttatcagcc aggacatatt tattcaagtg
    31321 gtattactgg tctagctcag attttgacga ctttgtcaaa atcactgata ggattcgaag
    31381 taccggtatc aacaactttg tatttactga atataccttt gtttgtattg gcgtggttaa
    31441 aaatcgggaa gaagtttaca attttcactt ttatcacagt cactttgacc tccctttgta
    31501 tccatatttt accggaaaca gtcctatcta ccgatccaat catctgtgcg ttgtttgggg
    31561 gggctgtgat gggactaggt attgggctag cgttgagaaa cggcctatca tcgggcggtc
    31621 tagatatcgt gagtatcacg attcgtaaaa aaacaggaaa gtcgattggt tctatttcga
    31681 tctacttcaa tgcattgatc gtttttgttg ccggaattct atttggctgg caatatatgt
    31741 tttacagtac gttgtctatt ttcgtcagtg gaaaagtaac tgatgtcgtt tatactaaac
    31801 aaaagaagat gcaggtaatg atcgtaacga aacatccaga aaaagtagta aatgaaatcc
    31861 aaaactgtat gcgtagaggg atcacgatca tcaatgaagc agaaggtgct tataagcatg
    31921 ataagcagac agtattgatg acgatcgtta cacgatacga actgcctcta cttagagaag
    31981 caatgaaagc ttctgatcca caagcttttg taagtattgc agaaaacgtc cagatacttg
    32041 gtcgtttcta tgaggatggc atttagatcg agtttgacaa aaattcatga aatactgctg
    32101 tagacagacg ttcgtttgtc tgcagttttt ttctaccata gtagaatcag caaagaaaaa
    32161 ctgctttttt atttgaaatt ttcttaaagt tgaaaaaaag catgtttatt tttttaaatt
    32221 tatgggatga tagaaaaaaa tagtagagaa aggacacgat tctacttgct attttcactt
    32281 aatacccgta tattacgaat gaaaaaagtt tatgaaaagt tggaatattg aatggaaaaa
    32341 caaaaaaggt taaaaaacag ccgctacatc actgggtttg atgggctccg ttcattagct
    32401 gtggtgggtg ttatcttcta tcaccttctg ccaactagta tgaaaggcgg ctatttgggc
    32461 gttccgattt ttttcgtcgt atctggttat ttgatcacgg atctgctgcg gcaggaatgg
    32521 gaacaaaatg gaaaaatcaa tatttggcaa ttttatgtca gaagaatgaa gagactctat
    32581 ccggcacttg tttttatgct tgtgacagct tcggcttata tcactttgtt tcagcgaggg
    32641 ctgttaaaca atcttcgagg agttgtggtc agcagcttac tgtatgtcaa caactggtgg
    32701 caaatcaata acggtttatc ttatttcgat cgatttgcta atgagtcacc gtttacgcat
    32761 atctggtctt tagcagtaga aggtcaaaac tatttggttt ggccgatctt gtttgtattg
    32821 ttgatggtat ttgttcgtaa aagaaaatgg atcttttata ctgtgttagg tacatccttc
    32881 ctctccgcca tcttgatgat gatcttgtat acaccaggag gcgatccaac ccgtgtttat
    32941 tacggtaccg acactcgtct gttttctata tggttgggaa gtgcgcttgc gtttgtttgg
    33001 ccaagtacgc gtttaaagaa aaacatcccg aaacaagcga aaaatattct gaatatcgct
    33061 ggaggaatct cgcttttggc actgattctt tgcttcttct ttttagatga tcattacaat
    33121 ttcatctatt acggaggaat gctcctagtg agtctgttat gcgtagtgct agttgcagtg
    33181 acagcacacc ccggagcaag tttgaatcga tggctgacaa atccagtatt tacttggatt
    33241 ggcaaacgaa gctatggcat ttatctgtat cagtttccag ttatgatttt ttatgaagca
    33301 aaggtgactg atattgccga tcatgttttg ttgcatactt tagtggaaat cacattgatt
    33361 ctaatcatca gtgaactttc ttatcgatat gtggagcgtc cgctagcacg ttttgattat
    33421 ggtcgtacat tccaagtgat gaaaggatgg ttcagcaaac cgatcatcag taagagcaaa
    33481 ccatgggttg ttccaggcac attacttgta gcaattgcac tcgttggttt cgttacggca
    33541 ccgaaaaacg ctgtaacagc cgatcaaaaa caactgcagg caaaaatcgc tgaaagtaaa
    33601 aaattagcag aagaaaccag aaacaattca gaaaacacca ctagttcggt tgaccaagcg
    33661 atccttgata agtacgagtt gtccaaggca caagggaata aggcacaaaa attagaacta
    33721 acggcatttg gtgattcagt tatgttggat gctgcaacgg atctacaaga actttatcca
    33781 aaagtagtgg tagatggaga tgtcggacga caattatatg ccagtgtacc gtacattgaa
    33841 aaattaaagg aacaagattt gttgaaagac actgttctga tcggactagg aacgaatggc
    33901 tcattctcgg aagctcagtt tgatagtgtg atggatgcaa tcggtgatcg aaaagtatac
    33961 tgggtcaatg tccgagtacc gacgaagcgc tggcaaaatg acgtgaatgc gatgcttgaa
    34021 cagatgacga aaaaatacga caatatgacg ctgattgatt ggtacagcta cagtaatgac
    34081 catagtgact ggttttatga tgatcaagtc catccaaatc ctgaagggat gacacattac
    34141 attcacttag tcagcgaagc cttgctagga ggaagttcaa gtacgaacag cagtgagaca
    34201 aacgtgacag aatgatagct acaaaaaact tcaggcaaaa acatttgttt ttgcctgaag
    34261 tttttttata tttaccgtgt ttttaacatt catatagatt caggaagcaa aacggttgag
    34321 tgtgtctgta aataacgttc tttttgtttt cgggtgagtt ttttgaatgc agcttctgct
    34381 tttgttgctt cgcttcttga agaaaatact tctgcatgga tcatcttaac aggtcttctt
    34441 ttttgaagac gagtatattt agcaccagta ccattgttat gttcctctaa tcgtctagaa
    34501 agatcggttg tatatccacc ataaaatgtc tgatctttac agaataatac gtaaaaataa
    34561 tgttcatttg ccatagagca tctcacgaat ctctgcagtg tattctccat ccatattgta
    34621 agtgatcaat ggtggagcga ctttgaatcc gtctaatttg ccttctttga ttccttcaac
    34681 taacaaaata tttgcctctt ttccaggttt tgggtaaaca aattggatcc ttttaggtgc
    34741 aattcgatag tcttccatga cctgaatgat ttctaagaac cgatcaggac gatggaccat
    34801 agtaaagcgt ccatttgttt ttagtagctt acttgaaata tcgatcactt cttctaacgt
    34861 cgtatgaatc tcatgacggg cgattgccag gtgtttatta gggttcgttt tatttgttgg
    34921 cagccctttg aaataaggtg gattacagac gactaagtca caagaattat gtcgaacgac
    34981 agataagctg tctttcagat cgatggtgtg gacagtcatt tgttcattta aatggttaag
    35041 cgcgatacta cgtcttgcca tgtctgctag acgaggttga agttcgatag cgtcgatagc
    35101 cgcctgggtt cgtttactta aaaaaagtcc aactgcgcca tttcctgcac aaaggtcaac
    35161 aatcttccct tttttaggta cacgggaaaa gtgagcaagc agcacagcat ctaaagaaaa
    35221 agaaaacact ttggaacttt ggataatctt gatatcttct gcgtataatt ggtcgattcg
    35281 ttcgtcttcg tgaagcatgg attccctcca aaatgaaaaa aatagtcgtc tgtattatac
    35341 tatttttatt aaaaagaacc aaggtggctt gtcaaacctc tattttttat gcatactatg
    35401 accataagaa gggaaaggaa gagactatgt tttatcgatt tatgcgcggg gtagttcgag
    35461 tactattagc cttagttaat ggaaatgccc gctatgagaa taaagaagtt ttaccgcaag
    35521 atgagaatta catactagtt gctccccatc gtacttggtg ggacccatta tatctggcgg
    35581 tagctgcagc acccaaggaa ttcagcttta tggcaaaaga agaactgttc aaaaatccag
    35641 ttctgcgatt tatattaact cgatccaatg cttttccagt taaaagagaa aatccaggac
    35701 caagcgtcat taaaacacct gtaaagattt tgaaatcgac aaatttgagt ttgatcatgt
    35761 ttcccagtgg gacaagacat gctacagaac ttaaaggcgg aatggcattg atttccagaa
    35821 tgtctaaagc gaaaatcgtg ccagctgtat atcaaggtcc gttgacactt ggggatctgt
    35881 tcaagcgtca gagagtgaca gtgcgtttcg gcgaaccaat cgacttatca gatatcaaga
    35941 aaacggataa agaaggtatg gcggagatcg aacgacgaac acaagcagct tttgacaaat
    36001 tggacaaaga agtgaaccct gatttcaaat atgaagtcaa aaaaaaataa aatgataagt
    36061 ttatgcgtgg gcggtctttt gaatctactg tcctgttcag ttcagacttt ttcaatgaaa
    36121 acgagggaga gacgtcaagt ctgccctctt tttgcgttcc aatatgtaaa atagaagaca
    36181 ggtgtcatgt aatggatcaa agtgttataa taattagaag gacatttttt gaggtgattg
    36241 aatgcgtttt ttacatacag ccgattggca tatcggaaaa aaactacaag gttatgactt
    36301 gattgaagac cagcgtcatg tactatcttc tatactagat atcgcgaaag aagaaaaagt
    36361 agaggcaatc gtgattgccg gagacttata tgataggagt gtcccagctg ttgatgccgt
    36421 agaattatac aatgaattga tggtcgattg gaatttaaag gaaaagatcc cgatttttgc
    36481 tatatcagga aatcacgata gcagtacgag actttcagcg ggtacgccat ggttcagtta
    36541 ttcgaactat tttttgcgaa cacagctagc agaagcattt gaaccagtcg agtttaaaaa
    36601 cgtacaattt ttctttcttc cttactttga accaattgca gcgagattat attttgaaga
    36661 tgacaatatc cgaacgatca agcaagcggt agccaaggtg atagataaaa tgcaggagct
    36721 atttgattca gaaaaaaaac aagtattgat tagccatttt tttgtaatgg gaagtgtaaa
    36781 atctgattcg gaaacgaaaa tcgaagtagg cgggttggat tcgatccctg gtgaactact
    36841 tacaccgttt gattatgtag cactaggaca tttgcataat caagctgctt tgagacagga
    36901 taatgctcgc tatagcggtt ccccattgaa attctcttta tctgagatca accaaaaaaa
    36961 aggcgtatgg atcgttgacc tgacaacagg cctggagttg aattttaggg agatcgaacc
    37021 cctgcatgat attgaagaaa taacagcgag tttcaaagaa ttgctggatc ctgcctttta
    37081 tcagtccgtc aatcgggaga attacatcta tatctatctc actgatagaa cgatcatccc
    37141 gaatatgatg aaccagcttc ggcaaatata tcctcgtatt ttggggattg aacgggcaaa
    37201 cggtcgagca gaacaaacaa agcgcaaacg aaaagtacta gaaatgaaag atcctcaaaa
    37261 attagcagaa gcatttttta gtgaaatgac ggaagagcag ctaactgcaa accaagaaaa
    37321 atggctcgga gaaacgttgc aagaaatcat ggaaatggaa tgatcaagaa tgaaaccgaa
    37381 aaaattacaa cttaaaaatt ttggtccttt tatcaatgag accgtagatt tttcacgttt
    37441 gacagaagca ccgctttttt tgatcagcgg gaagacagga gctggcaaaa cgacgatttt
    37501 tgatgggatc accttcgcac tttttggtga aacttccgga agacttcgct ctggaaaaga
    37561 gatgcgttct ttgtttgcta caccagacga agaaacaagc gtgacttttt cttttgaaca
    37621 tcagcagatg agctatgaaa tcgaacgaaa accagaacaa gttttagcaa aacgaaaagg
    37681 aaacggaaca aaaaaacagg cagccaaagt aacgttgacc atttttgatg ggaaaggaaa
    37741 agaaataaaa caaatcacaa aacgtacaga agcagatcag ttgatcagag aactgatgaa
    37801 tctcgatgcg aaacagtttt ctcaaatcgt tttactaccc caaggagaat tccgtaattt
    37861 tttggtttca tcaagcagtg ataaagagac tgttttacgt catttattcg gtactcaatt
    37921 tttccaacag ttcaatgagc gattaaaaga aaaagcaaaa caacagcaac aaaaattgga
    37981 tcatttagag caagagctgc atcttctgca aaaaaggttt gttttagtca aagaagagga
    38041 accagcagca gggtttgaag ccgttttagc ccaatggaca aaccatcagg caatactcga
    38101 aaaacaaatc acggaagaaa aagaagctct aacggaactt caggaaaaac aaaagcaact
    38161 agaaaattcc tactatcgtt ttgaaagctt gaaaaaaagt tatgaagaaa aaacgatatt
    38221 aataaacaag caaaaggaat tagctgctca aaaagacgaa atagaggaaa agaaacgatg
    38281 gattgggtat tatgaattta cgcaacgatt agtcgaacca atccagcgcc tacaagaaat
    38341 aaaagttgaa aaaatagaac tgtcacaaaa aagtagtgag caaacaaaga aactagcgat
    38401 gactacgcag aattatgaag agtggcaaaa aaatgaagca aaccgcgtac gccgacaaac
    38461 aaaaatcaaa gaagctgctc aaaaactgca aaacaaacag atgatggtgc caattgtcga
    38521 atccttacgt agtaaaaaac aagacgcaga acaattaaca atttcattgg ataaagaaga
    38581 attgaatgcc gagaagctgt atcaaaatct cgctatctat caggaaagaa ctcgaattct
    38641 tcaagaaaat ttactggatc aggaaaaact gcaagaagat cgtcttgctt ttggacagtt
    38701 aaaatatcta gatgaaaagc agcaagaaat agaaaaacaa aaagcaaaag acactgggtc
    38761 gctcgcacag ataagagaag aactcaaaaa agcaactgaa gaaataacaa aaaatagtca
    38821 gctattgaaa gaacagacag aacaagcaga acagctgaaa agccaatggg caaagcagca
    38881 aattgctcgt cttcagcttt ttttgcgtcc aggggagcca tgtcttgttt gtggatcaac
    38941 ggaacacccc atacaacaat taaaacacga acagccaaat aaggaagata tcttaaaagt
    39001 agaacaacaa ctggcagaag ctgagtctgc tgtagaaaga actcagcaaa tcattgccaa
    39061 aagtgaagca catgaaaata atcttcaaca acaattatca gatttagaac aaaaaatcat
    39121 ggcaacgaat atacaattgg ctgaacaaga agaacacttg caacaggctt tgaaaaaggc
    39181 atttcctgag ataacagaac aaaaaacaaa aacaactctt gtagtaatcg aacaatcttt
    39241 agatagacga aaaagcaaga tggccaatgc aagaatagag ctggaagaaa taagacaaca
    39301 agcagaaaag ctcgaacaac aattagctgt ctacaaacag cagcagacag aaaaaaataa
    39361 tcagctccag caactgcaag gagaaatcaa aagtttagaa caacaattgc aagatacgga
    39421 tagtaactgt ttagaagagg agatacgacg acttgaaaaa cagttagaag aagactcgaa
    39481 tcaactagct gttgagcaga aagcaggagt gcaattgttg caagatcttc atacgcttcg
    39541 gacacagctt gatcttcaac atgaacaaat agaaaaaata gatgaaaaaa tagaaaagga
    39601 acaagaaaga atagctaaaa agttagaaag ccagtcgtat ttttcaacaa ttgaagaaat
    39661 ctgtgcattt gcacaacagc aagcacaata taaagaaaac caacgtacag ttacttctta
    39721 tcatgaagag caattagtga cagctgaccg gctgcgtcaa ttagaaaata tccagctaac
    39781 tgagacattc ccagatacag aagagatcag ccaacagtta gaagaaataa gacgtatgat
    39841 cgaaataaag caagaaaaga tatacggttt acaagaacaa aaaattagta atcaaaaaat
    39901 ctacgatgaa tgtctttcga tttatcacac aagccagacg aaattagatg agcttacgca
    39961 attacagcag ctttcgcaaa cattcaacgg agaaaatcct aagaagacta gtttggaacg
    40021 gtatgtgctt caggtttatc ttcaagaagt gttacaagta gcaaatgatc atctccaacg
    40081 tttaacgaaa aatcgttatc aatttgagct agcggatacc attggcagtt atcgagggaa
    40141 aaccggatta gaaatcaata tctatgatga tcaggcaggt atgtctcgaa gtgcgcatac
    40201 cctgtctggc ggtgagagtt ttattgcagc actttcttta gcattagctc ttgccgatgt
    40261 gatccagaca caagctggtg gtgtagcaat cgatgcattg tttattgatg aaggatttgg
    40321 gtcattagat gaagaagctt tggaaatggc aatggaagct ttagaaacga tcgaaagtga
    40381 aggaagaatg atcggcatca ttagtcatgt aagagaattg aaagaacgag tattacaaca
    40441 aataagaatt gatacagaag gtagcggaca aagcaaaata cgctatcaac ttggataaaa
    40501 agggagattg gtaactatga aatggagtat tccagaaaaa gtcattgcac gtggacgtca
    40561 atacttgcaa gaaggccgag tgttatcggt tgtccctgac caagaagaaa acgtgtggca
    40621 tgcagaagtc ttgggcagtg aattgtatat ggttgatttg gatggtacag caaaagagat
    40681 agattactgc caatgtccct attgggagga acataaatat tgtaagcata cagttgctgt
    40741 ggaactttat ttacggtcga aaaatctatc tcgtatcatg aaaaaagacc agccaatgct
    40801 agaaccggta aaagcaacaa gtgagggaga aatcattgca aaaggttttt ctcgtctaaa
    40861 aacacaaaac aatcctcaag cggtgcaacc tttgattatt gaataccaag tagaaacgat
    40921 tgagactaat cagtatcacc cagagctttc tattttggca ctttacttgc gtatcggttc
    40981 attggcatca ccgaaaaaaa catatatcgt aaaaaacatc tatgattttt tacaagctta
    41041 cacagaaaaa gaaacttaca ctgttaataa acagtaccag tttcgtctag ataaacgggc
    41101 gtttcaaaaa gaagatcaaa aaatactcac gcatcttgca ggaagtgctc agacgcatca
    41161 attattaggt acgaacggct tacaagtcaa aggaaaacta gataaaagat atctgcttct
    41221 cccagtagaa caagcccgct tcctgttaga gcagatgaat cagactacac gtttgcatct
    41281 gcagataaat gaacaaaacg atcaaggaat acaattttcc gatcaaaaca aacctttatc
    41341 attcaaagtg gaaaaatttg gagaagatta tttgctgcaa gcattgaatg attttgattt
    41401 tttctttatg cattatcagt ggggagttat ccaagggaca ttttattctc tgacgaaata
    41461 tcaacaaacg gtttatcaaa cttggaaaca attgattcgc cgattggaga aaccagaagt
    41521 agtgttcaag aaaaaagaat taccgtcttt gtttaaagag attatccctc tgctgtcaga
    41581 gatcggcgac gtagctattg cccctgcagt agaagaggaa gtagcagata tccccgtcga
    41641 atttattttc tttttccgaa aagcaaaagg aaaaatccaa gctcgagtcg atttcgtcta
    41701 tggcgaagtc atctattcga ctgacccgaa gcatgaggtc tcgacagaac aggcttttca
    41761 ggtgttacgt gacacagtag aagagaaacg agtacttgat ctattcagaa tgtatcgcta
    41821 ccagaaaaat gaaactggtt atgaacgtcc attgccaagc ggggaagaac tatatgcctt
    41881 tttccgcaca gaactatctg tcttccgtca gtttggtgaa gtcagacttg gaagaaaatt
    41941 gcgagagttg tatttagatg cgcataaaca tcaaccgaaa atcgaagtaa ccgagaccgg
    42001 ttcatggctc gatattcgat tcgatgtgac agggatagag gagcaagaaa tcgatcatgt
    42061 cctgcaaagc ttgctgagaa atgatgcttt ttatacatta gaaaatggtc aggttctttc
    42121 ttttgattca gaagaatttc aacaaacaag ccaagtgttg caacaattac gggaatcgat
    42181 acgtacagaa gaaggaacga tccatgtacc taaaaatcaa ggattgatca ttcaaaatca
    42241 attggaaaaa agcaatgcta cttttagtga atcgttccaa acgatggtac aagatctcat
    42301 tcatccagaa agataccagg cacagcttcc caaaggattg aatgcaacga tgagagatta
    42361 tcaaaagcaa ggttttcgat ggttgaagat gttaggtcat tatcagtttg gcggtatttt
    42421 agccgatgaa atgggacttg ggaaaacact acagacaatt gcctttttac tttcggaaaa
    42481 agaagaacgg aaaagcttct ctgctttgat cgtagcgcct gcgagcttaa tttacaactg
    42541 gcaggcagag gtgagaaaat tcgccccttc tttaagtatc caagtaatca atgggaataa
    42601 aaaagaacgt gaagaattac tggctaaaga cacagatatc cgagtgactt cttatgccag
    42661 cttaagacag gatctagcta attatcagtc gcaaaaaatt gattatttga ttcttgatga
    42721 ggcacaaatg gtcaaaaata gcagtacgaa aactgcacaa gcattgagag aattagctgt
    42781 acctcagcgg tttgcactga gtgggacacc aatcgagaat aatttagaag aattgtggtc
    42841 attgtttgca acgattatgc caggattttt cccgactaaa acaaaattca gggaacttgc
    42901 cgcagaagaa attgcgcaaa tgattcgacc gtttatttta cggcgagata aacaaactgt
    42961 gttgaaagac ttgccggaaa aaacagagat gaatctatat tctgcactta cagaagaaca
    43021 aaaaactgtt tatttagctt acttgcgtca aatgcgtgaa gaaatcacat caatggattc
    43081 tgaagcattc aagaaaaacc ggatcgggat acttgctggt ctgacaagac tgcgacaaat
    43141 ttgctgcgat cctcgtctgt ttattgaaga ttaccaaggc ggttccggca agctcgaaca
    43201 agtaaaagat ctactggtag ctgccaaaga gaacaaacga agagttttgc tgttttctca
    43261 atttacaggg atgctgacta tcttgcaaga agagttagcc gagctaggga tctcgacatt
    43321 ttatttaaga ggcagtacga aaccacaaga tcggttaagt atggtagacg catttaatgc
    43381 tggcgaaaaa gatgtttttc tgatttcctt aaaggctggg ggaactggat tgaatctcac
    43441 gggagcagat acggtcatct tgtatgacct ttggtggaat cctgccattg aagaacaagc
    43501 tgctggacgt gcacatcgga tcggacaaaa aaatgtggta gaagtgtggc gtatgatctc
    43561 tgaaggaacg attgaggaac gcatggattc actccagcaa gaaaaacgcg aactgttcca
    43621 aaaagtgatc caaggtaatg aagaacagtt gacgaaactg actgaagaag acatccgcat
    43681 gattttaagt gtaggagaaa tcgaggagta agagactcga aaaagcgttc agtaatgggt
    43741 aagaaagcct ttctaaagaa gcgattgttt atttgattta aaaaatagca aggaggctgg
    43801 gattccattt tatcccagct tccttgctat cattttttta tttctatttt taaaggttat
    43861 acaaagattg tcttcattgt ctctaacagc tgatcaaaag aagaaatctc gatatcgcaa
    43921 attggagtct gttcaatttt gcgttctcga tggttgaacc aaagcgcttg ccagttagca
    43981 ctttttgcac ctagaacatt attgtcgtaa ttatcgccaa cgtataaggt ctcttctgga
    44041 agcatatgaa attctttctc agctagctga aaaatctctt tttctggttt ttggaaacct
    44101 gttgcttgag aaatgagcat attgcgggaa ggaatccaat tgttcaattg aagttgcttc
    44161 agtttttttg tctgatggtc agtcggccca tttgtgataa ttcctaatgg gacattcttt
    44221 tccttcaaga aatcgagggt ttttttgacc tcctcatgca agcagatatt atcaagttct
    44281 tcctcgtaaa ttttttgaaa taagaggcca tcttcttccg taatatgagg gtagtctaaa
    44341 tcttttagtg attggctgat ccgatgtgct cgcatatatt ctagtgtcca atctcctgcc
    44401 attacttttg ggaagttttc atcactatga tggcggaacc ggatatatag tggatgcata
    44461 tctgcatctg aaacaagcgg aacgactctt ttgaccgcgt ttcgaaatgg ctgctgctga
    44521 tcatacatcg tatcatcaac atcaaacaca actgatttaa tcaaaatttt acacgccttt
    44581 cggttttcat tgattttttc acaaatcctt gactattgta acagaaaaaa ttgtctaaaa
    44641 aagctgataa ataaaggttt ttcttactat atttctattt ccttgacaga ataaggtttt
    44701 tatatttcag tttttttcac taaaaatcgt gaaacacgtc aataagtttg atgaacaaat
    44761 taatcattat ggtagaagtc gattgattta ttttaatgc
//
LOCUS       DAFLVO010000016        44514 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.016, whole genome shotgun sequence.
ACCESSION   DAFLVO010000016 DAFLVO010000000
VERSION     DAFLVO010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.016"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            19..1446
                     /locus_tag="L1U99_000918"
     CDS             19..1446
                     /locus_tag="L1U99_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1211478.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1538..1903)
                     /locus_tag="L1U99_000919"
     CDS             complement(1538..1903)
                     /locus_tag="L1U99_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBN1211479.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(1900..2265)
                     /locus_tag="L1U99_000920"
     CDS             complement(1900..2265)
                     /locus_tag="L1U99_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBN1211480.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2457..2705)
                     /locus_tag="L1U99_000921"
     CDS             complement(2457..2705)
                     /locus_tag="L1U99_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211481.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2704..2832
                     /locus_tag="L1U99_000922"
     CDS             2704..2832
                     /locus_tag="L1U99_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HBN1211482.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2889..4583
                     /locus_tag="L1U99_000923"
     CDS             2889..4583
                     /locus_tag="L1U99_000923"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HBN1211483.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4587..4706
                     /locus_tag="L1U99_000924"
                     /pseudo
     CDS             4587..4706
                     /locus_tag="L1U99_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            4683..4856
                     /locus_tag="L1U99_000925"
     CDS             4683..4856
                     /locus_tag="L1U99_000925"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211484.1"
                     /translation="MQAFEHRLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKGV"
     gene            5234..6367
                     /locus_tag="L1U99_000926"
     CDS             5234..6367
                     /locus_tag="L1U99_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HBN1211485.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6398..6718
                     /locus_tag="L1U99_000927"
     CDS             6398..6718
                     /locus_tag="L1U99_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HBN1211486.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(6747..7211)
                     /locus_tag="L1U99_000928"
     CDS             complement(6747..7211)
                     /locus_tag="L1U99_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1211487.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7343..8596)
                     /locus_tag="L1U99_000929"
     CDS             complement(7343..8596)
                     /locus_tag="L1U99_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1211488.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(8625..8942)
                     /locus_tag="L1U99_000930"
     CDS             complement(8625..8942)
                     /locus_tag="L1U99_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBN1211489.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(8968..9288)
                     /locus_tag="L1U99_000931"
     CDS             complement(8968..9288)
                     /locus_tag="L1U99_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1211490.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(9752..11167)
                     /locus_tag="L1U99_000932"
     CDS             complement(9752..11167)
                     /locus_tag="L1U99_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1211491.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(11184..12500)
                     /locus_tag="L1U99_000933"
     CDS             complement(11184..12500)
                     /locus_tag="L1U99_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1211492.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(12650..13348)
                     /locus_tag="L1U99_000934"
     CDS             complement(12650..13348)
                     /locus_tag="L1U99_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBN1211493.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(13637..14593)
                     /locus_tag="L1U99_000935"
     CDS             complement(13637..14593)
                     /locus_tag="L1U99_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBN1211494.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(14706..15539)
                     /gene="msrA"
                     /locus_tag="L1U99_000936"
     CDS             complement(14706..15539)
                     /gene="msrA"
                     /locus_tag="L1U99_000936"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBN1211495.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(15714..17348)
                     /locus_tag="L1U99_000937"
     CDS             complement(15714..17348)
                     /locus_tag="L1U99_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211496.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(17335..19203)
                     /locus_tag="L1U99_000938"
     CDS             complement(17335..19203)
                     /locus_tag="L1U99_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211497.1"
                     /translation="MISIIWFLFFFIFFSYLKVIKIDSFLVYHTSAMKNLTQNLLKKD
                     NSSILKIELKKENNKSMKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLS
                     RIKGLSSIFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLL
                     NICTILISFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVL
                     YYAYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIK
                     FVVVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNN
                     DITTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPIS
                     LLQFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAK
                     VIQSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKY
                     KAADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENK
                     IEITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            19169..20806
                     /locus_tag="L1U99_000939"
     CDS             19169..20806
                     /locus_tag="L1U99_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211498.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSKGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(20951..21691)
                     /gene="truA"
                     /locus_tag="L1U99_000940"
     CDS             complement(20951..21691)
                     /gene="truA"
                     /locus_tag="L1U99_000940"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBN1211499.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(21882..22517)
                     /locus_tag="L1U99_000941"
     CDS             complement(21882..22517)
                     /locus_tag="L1U99_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBN1211500.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(22664..23905)
                     /gene="sstT"
                     /locus_tag="L1U99_000942"
     CDS             complement(22664..23905)
                     /gene="sstT"
                     /locus_tag="L1U99_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HBN1211501.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            24103..25101
                     /locus_tag="L1U99_000943"
     CDS             24103..25101
                     /locus_tag="L1U99_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211502.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            25114..27132
                     /locus_tag="L1U99_000944"
     CDS             25114..27132
                     /locus_tag="L1U99_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HBN1211503.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(27192..27908)
                     /locus_tag="L1U99_000945"
     CDS             complement(27192..27908)
                     /locus_tag="L1U99_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBN1211504.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            complement(28135..28677)
                     /locus_tag="L1U99_000946"
     CDS             complement(28135..28677)
                     /locus_tag="L1U99_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBN1211505.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(28682..28909)
                     /locus_tag="L1U99_000947"
     CDS             complement(28682..28909)
                     /locus_tag="L1U99_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBN1211506.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            complement(28988..30868)
                     /locus_tag="L1U99_000948"
     CDS             complement(28988..30868)
                     /locus_tag="L1U99_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBN1211507.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(31057..31671)
                     /locus_tag="L1U99_000949"
     CDS             complement(31057..31671)
                     /locus_tag="L1U99_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1211508.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            31813..32373
                     /locus_tag="L1U99_000950"
     CDS             31813..32373
                     /locus_tag="L1U99_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1211509.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
     gene            complement(32678..32992)
                     /locus_tag="L1U99_000951"
                     /pseudo
     CDS             complement(32678..32992)
                     /locus_tag="L1U99_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
     gene            complement(33246..34881)
                     /locus_tag="L1U99_000952"
                     /pseudo
     CDS             complement(33246..34881)
                     /locus_tag="L1U99_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(35320..36189)
                     /locus_tag="L1U99_000953"
     CDS             complement(35320..36189)
                     /locus_tag="L1U99_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1211510.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            complement(36209..37330)
                     /locus_tag="L1U99_000954"
     CDS             complement(36209..37330)
                     /locus_tag="L1U99_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBN1211511.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            complement(37332..37727)
                     /locus_tag="L1U99_000955"
     CDS             complement(37332..37727)
                     /locus_tag="L1U99_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBN1211512.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            complement(37746..38552)
                     /locus_tag="L1U99_000956"
     CDS             complement(37746..38552)
                     /locus_tag="L1U99_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1211513.1"
                     /translation="MNKMSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALS
                     PILRKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKV
                     GTMGPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEF
                     GYKQGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQP
                     MLDKILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            complement(38545..39333)
                     /locus_tag="L1U99_000957"
     CDS             complement(38545..39333)
                     /locus_tag="L1U99_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1211514.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            complement(39347..39823)
                     /locus_tag="L1U99_000958"
     CDS             complement(39347..39823)
                     /locus_tag="L1U99_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1211515.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            complement(39895..42552)
                     /locus_tag="L1U99_000959"
     CDS             complement(39895..42552)
                     /locus_tag="L1U99_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1211516.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKR
                     ILEDSFPRDTDLVIETCDYYSLVNENYLSELRKENNILFIVGTLNPHLEDVEFFSIED
                     MILGMNISKFSNQLNRHFNDNELKVLNNNILKNFSLTNLMEQLTILNPTKLLERVSDA
                     IYILQNDLGISFDNNTCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEFQKFQTHFK
                     QSFSVVEHYYSVDIPIHEVKYVYDYVKRA"
     gene            complement(42571..42975)
                     /locus_tag="L1U99_000960"
     CDS             complement(42571..42975)
                     /locus_tag="L1U99_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
                     /protein_id="HBN1211517.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFLASHIYGKILSAKFE"
     gene            complement(43207..43464)
                     /locus_tag="L1U99_000961"
     CDS             complement(43207..43464)
                     /locus_tag="L1U99_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBN1211518.1"
                     /translation="MEDSPELFPMLKDRLNELTEKRRQLQIRENEILGIFQQQGEPIQ
                     VKDVQQILTSLDCFLIQSEKKQVKALYHTFIEKITFDPNQK"
     gene            complement(43589..43921)
                     /locus_tag="L1U99_000962"
     CDS             complement(43589..43921)
                     /locus_tag="L1U99_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211519.1"
                     /translation="MPLDLSTGRKIRFSEIQYEGIGFTLIDLKNSTFEIKEGLDLKNL
                     LCADDKIKKIQLYKVPILTPTVLTMLEMENNINYIDSGSDLLIRWQVITNFLMELKKY
                     SNTQTKFS"
BASE COUNT        14076 a         8704 c         7024 g        14710 t
ORIGIN      
        1 caaggcggag gctctactat gattgaagaa tatattgaga aaaatatttt aagacagctg
       61 tttttatgtg ggcaattcta tgtaaataaa gaagtcaatc tagaaaagct ctccaatctc
      121 ctgcatgttt gcaaaaccac tttactcaat gatatcaata acataaaaaa agaatttgaa
      181 gaacagatcg cttatacaca tcgggaaaag gaccgttaca ctttatattt ttcagaacat
      241 atacctcgat gcaagatcat gcagcaattg tctcaaaatt cgttgttttt aaaaacttgt
      301 ctgctttatt tggaagaaga tgaacctgat tatcttcaat taactgaatg tgaattcatc
      361 tctgtcagca aagcttattc attaaaaaaa caagtattag cttattttaa tgactgcggg
      421 atcgaaatcg accgctactc ccctcgattc actgaaatgg aaagacgtct gctgcttctt
      481 aatgtgtcgt atcgtttagg cggttttaat tcttgggagc tacctgaatc gttttttgaa
      541 cgtgccgatc gtttcattga atccgtaacg gaaaatagtg gcagatttta tgataaagaa
      601 aataaagaaa tcttatcgat tggttttgct atcagtttcc tacgccagca agtgtgtgct
      661 gtgacaatag attcaaaatt tatcgaagaa atcaaaaaac gtcctattta caattatgtc
      721 gaatcagcat gggaaaacac tgatttccaa acctattata aaaaagaaga attcgccttt
      781 attttgacac tattcaatct ttgtaattat ggtttccatt cttatcagtt gattgcggaa
      841 gactttcaac agctacacca agtgtttatt gacaatactc ccgaaataaa agaactagtt
      901 gctacctttg aatctcactt caatcaagaa ttattcggaa accaaccgtt cgaacgtgcg
      961 ctgattcatc tgatgcgttc ggcttgggat aactatcaat tattcatgcc agaaaaattt
     1021 tatcttttaa atgaggaaca gacaaattta tataaagaag tccagacaat tttttccagc
     1081 tggtccagcc agttacctta tgatctacgg ttgaatccta attgcatgcg ggcttttgtg
     1141 atcgaattga gcggaattct ccgtctgaca aaagaacatc tgactatcta tatcgtcaca
     1201 aattcggatg ttcattatct gatttatcgg gaagccttgg aagctgtaac tactttcgat
     1261 tttcaagttg caccaacaat ttattcaagt atatctgata taaagaagta tgcgcagcag
     1321 tcctcaaacc gggtattatg tgaacgtaca ttatatacac cagatgcggt ccaatatgaa
     1381 aatattattc ctatttcgat caatacgatc gatcgagcta tcatttcagc tgtgcaaaac
     1441 aaataagggg ctgtgacaaa aatcatgtca cagcctctta tttgttgaag atgcccattt
     1501 ctgtaacaat ctcttgatac acgtcaggct cacaacctca cttattttgg acatctacgg
     1561 gtccgatctc tttatttaaa aaataagaaa tgatggttcg gataactacc aacgccgcta
     1621 gttggaaaat atcctgcaag gtaggtttga taatcgattc gatgatccca gctgaaacaa
     1681 gaatttccaa acttagaagt atatagcctc ccaacatctt tttaatagca ttgttctcgc
     1741 tgactcggtc gctttgcact tttgtatgga caaataaata tttcaaaaaa tccttgattg
     1801 atagacaaac accccaaacc aataaacaga tagcaaagat atcaagtccc agtacaagtt
     1861 tttcgaaata tggaagaaga aactgcatca actctgtcgt catcctacct ctcctcttct
     1921 ttgtttttct ttgtcttcta tttcctgatt caagaaataa gaaatgactg ttcgaatgat
     1981 aataataagt gcaagcttca aaatatctgt ccaagtcggc ttgataactg actcgatgat
     2041 atcagcaacg actagtactt ccaagcttaa caaaatataa cttgctagca gttttcttgt
     2101 atctgcatta cgagtattac gttctgcata gtttttcttg acatgagacc aatcaaaaag
     2161 tttgaataga acaagaacga tcccgacaat taagataccg atagaacaaa tatttaaaat
     2221 agcaatgatc cattctagaa attcaattaa atttgagcga aacatatacg ctacctactt
     2281 tcttttaatt tgttcctatt cttttattgt aaaagaaagt taccttgttc gtctatttaa
     2341 aagttgttct aatgataacg gttcgcttaa atttttcttt ttcactctcc catttttctc
     2401 cctccatcca taaatcgtgg aagtatccaa aacaacgtag caagttaaaa taaggcttag
     2461 tccgtcatca gcttttcaaa gaagcactgt ctcggtgctt tttttgtacc caaatttcta
     2521 aaaatagaac catacacctc ctcaaatctt ttcttcttac ctaccctatt tttatttaca
     2581 ggaaaatcag acacttcttc ttttttgtca aaatttcctt tttcttctcg tcctatcatt
     2641 tggcattcta ataaaaacga actatccttg gatatagaaa gagaaaacaa ggaggcgttt
     2701 ttcatgagta aaaaattaat caaagtcggc atcggtttag gtttgcttgc ccttggcgct
     2761 gcatatctag gaaaaaagac aggactattc gaagatgaca gtcatttata tgatgaattc
     2821 gaatcaatct agcatcctat ttagttgaat cactacggac atacttggaa gacattggag
     2881 gaatcacaat gagaaaaagt aaagcaataa tgattggtgc cggtattgcc aatatggcag
     2941 cggctgttta tttgattcaa gaaggcaaat ggaaagggga tcagatcacc ttttattcat
     3001 tggatgatca cggttcaaat gatggtgcac cgaccgacac tgtagtggat gaatattgga
     3061 ataaaaacca tccattagaa aaccaaaaag gctatattgc tcgaggcggt cgcatgctta
     3121 attaccgtac ctatgtagat ttgatggatc tgttaagtcg aataccttct gttactgagc
     3181 cagggatgac tgctgaagaa gatacgagag attttgatgc aaaacaccga acctttgaca
     3241 aagcacgttt gatggaaggt ggcaaaggaa tcattgatgg cggaaaactg ggattcaata
     3301 ataaagaccg tattcttctg actaaactga ttgctatgcc tgattcagaa gaagaaaaac
     3361 tagacaatat cactatcgaa gaatatttca aagatgatcc acactttttt gaaacaaact
     3421 tctggtttat gtgggaaaca acatttgctt tcagaacacg tagttctgct caagaattgc
     3481 gtcgctatat gcatcaaatg atttatgaat tcactcaaat cgaacatcta gtgggcgtca
     3541 atcgaacacg ttacaatcaa tacgaaagta ttatgcttcc tttgatcgag tacttgaaag
     3601 aacaaggatg caaaatcatt ttgaaccgcc gtgtcactga ctgggaattc aaagaaacac
     3661 cgatgcaaga tgaaatcact gtgactggtt tgaaaattac caatacactg actcaagaag
     3721 aagaatacgt tgtggtcgat gaagatacag cagttatttt cactaatggg tccattacag
     3781 attcagctac tttaggagat tacgaaacac cagctgtaga aaatatggat tatggtgcag
     3841 cttctagtct ctggaaaaaa gccagtgaac gtttctacaa cttgggaaat cctgacaaat
     3901 tctttgctga tcgagatgca agcgaatggg tcagctttac cctgacgacg aaaaaccatt
     3961 tgttgttgaa tgaaatcacc cgtatcacga ctcaagaacc aggaaatgcc ttgaattcat
     4021 ttatttcaac cacaccgatc acgccgttag gccaaaaaga tgtcaatatg tctattgtcg
     4081 tgcatcatca accgcatttt acgtctcaga aaccaaatga aacagttatt tggggttatt
     4141 tcctttatcc aagacgacgt ggcgaatttg tggataaaca gtatattaaa atgaatggaa
     4201 aagaaatgct agaagaactg attggacaac tttcaaaagt agatcctgga ccagtgaata
     4261 ttcgtgaaaa agaaacagaa attttcgaca gcgtaataaa taatatccct gtctatatgc
     4321 cttatgcttc cgcgttgttc aataatcgtg ccaaaagcga tcgaccaaaa gtcattccta
     4381 aacattcgac caatctggcc tttacaggag aatttgtcga gcagccttat cagatgatct
     4441 ttactgaaca aagtgctgta cgttctggag aaatcgctgc tttccatttt gcgggtattc
     4501 ctatgtcccg tcttgtcaaa acaccgcgtt acgacaaaga tattcctact ctagctcgtg
     4561 ccgcaaaaaa aatgtttgaa taatcaagag gttgtgaaaa agctgccctg catcaagtaa
     4621 taagaacaac caggctaaaa cagcttctta tgtttttgat ttggttggac ttattaccgc
     4681 agatgcaagc ttttgaacac cgtttaccaa gaggttatga aaaagctgcc ctgcatcaag
     4741 taataagagc agccaagcta aaacagcttc ttatgttttt gacttggtta gacttattac
     4801 cgcagatgca agcttttgaa caccgtttac caagaggtta tgaaaaaggc gtttagtttc
     4861 gagtatgaag aaaaattttg tgaaaatggt tcctcacgtt tttgcataaa tttgacttaa
     4921 taccgagaaa ctgatccctt ctgtcataac ctctttttat ttatgtctgt ttctttttga
     4981 aaacaactat tttttcaacg tttactctct tgccaatcca acatcatcta acggatacaa
     5041 ctatttcaat gattaccatt acactaaaaa atcggaaaca cacctctccg aacacaaata
     5101 cataagacta tagaatgttt catttaagaa aaaaagcgtt tcattatcaa aaaggtaaga
     5161 tctcctttaa aatgaaatta tctgtagtac taataatgca gacaatttta tgaatctgaa
     5221 aggagcatct ccaatgaaag cagtcacttg gcaaggaaaa cagaaaatgg aaatcagaaa
     5281 cgtagatgat ccaaaaatat tagaaccaac agatgcaatc atccgtatca cagcaacagc
     5341 catttgcggc tccgatctgc atctttacca tcatggtgaa gcagttttgg aaaaagggta
     5401 tgttgtagga cacgaaccaa tgggaatcgt tgaagaagtg ggatctcaag ttcaaacatt
     5461 gaaaaaaggg caacgtgtgg ttatcccttt taatattagt tgtggtcatt gtcatttctg
     5521 cctgaatcac atggaaagcc aatgtgatga atcaaatcca gatcagttat atggcgggct
     5581 tttcggattt ggcaagttga acggtaatca ttggggtggt caagcggaat atctaagagt
     5641 tccttatgca gactctactt catttgttgt accagataat gatcttcctg atgaaaaagt
     5701 tttatttcta tcagatattt tgcccacagc ttattggagc gttgaaaacg caggagtaaa
     5761 aaaaggcgat acagttgtga ttctaggttc tggtccagtc ggtctattcg ctcaaaaatt
     5821 cgctgttatg gctggagcag agcgcgtaat cgcagtagat ccagtacagc accgtctaga
     5881 taaagcggct aattacaatg gggttgaaac ttatttctta gaagacacgg cacaagctgg
     5941 aacagaattg tatgaactgg ctaaaggtgg cgcagatgtc attatcgatt gtgtaggaat
     6001 ggacggatta gagcctgtca aagaaaaagc gaaaaattta gtaagcttac aaagcggcac
     6061 aatctctcca ttacagatgg catcgcaagc tgtcaaaaaa tttggaacag tccaagtaac
     6121 tggtgtttat atgactccag cttcttctta cccgctgcaa gaatttttta tgcgggatat
     6181 cgctgtcaag catggacagg caccaattat ccatctaatg ccaaaaattt acgcaatgat
     6241 tgcagaagga ctattcgatc ctacacaaat cattactcat tcgctgccac tatcagaagc
     6301 agcacaagca tatgagatct ttgacaaaaa agaagataaa aatataaaag ttgttttgaa
     6361 accttgaatt cagtaaaaaa tacaggtgat tttctttatg cccaaaatca aacgaaatac
     6421 ccatgagatc gaaataggaa aagaagaaga tatcgaaata cgaggacgtc gcttccgctt
     6481 ctatttccaa aatcgttaca cattgatctc actggctgtc gatttattaa ccgggatttt
     6541 ctatattttt ggaagccttg cttccttaac taaaatcccc gatcgatatg gcacctattt
     6601 ttatttggct ggtgctattt tcttgacgat tcgtcctatt ctcagaatcg taaggaacat
     6661 ttttatttac gacgaaaaaa aagcaatgaa gagaacaagc aaaaaaaaag aggcatgaga
     6721 atttttcaaa tctcatgcct cttttttcac cctatcgtat cactttgata cagacgagcg
     6781 gtcgtcccac tttcttcctt gaccattgtc aaaaatgtcc actcgtatcg ttcataaaac
     6841 gtggtatgat ctgtaattaa gtaaagtttt tcgtacccaa gttgatgcat ttcttttctg
     6901 atttccgcta atatccgctt ggctatcccc tgcttacgct tttccggttc aacaaacagg
     6961 gcacaaagat ttggtgtcag atcagggcgg ttatggaagt cgttttcaat gacgcccgct
     7021 cctccgacga tggtttcttt ttcatctaag accacatacc attgaggaat actttcctta
     7081 ttagcgattc cagtacgaat actttcctca tacacaacag caggaactcc ccattttgat
     7141 gaaaaccaat tcgcgctttg ttttactaat tctgggtgtt ctcttaattt gatccagtta
     7201 tatgtaacca atgtttaaac ctccgactaa aataaaacgt ttacaaaaat tatacaagtc
     7261 tttatgaaaa ttagcaatga caacaatagt gatgtaaaaa aaaaaacgga aaacaatcac
     7321 ttgttctccg ttttttgatt aatcaagcat ctaaagcttc ttttcttctt tcttggatcg
     7381 tagctacctt gacgaacggt agatagatca aaatagaaag aaccaaattg acagcggcta
     7441 gtacaccacc tgcaatactt tttgttgcca atacaccgcc aataattggt ggagttaccc
     7501 atggaggcat aacggtagct gctggcacta aacctgtaga agtcgcaaag taagcaacac
     7561 taactaagac cattggtgtc aaaataaatg gaatgaacat gatcgggttc aacacgatag
     7621 gtaacccaaa catcgttggt tcattaatat tgaagacacc tggcgcaatc gacaagtttg
     7681 ttacaaccat atatggtttg tttttacgtc ctactaaata aatagctaac agtaaaccta
     7741 aagttgcacc tgttcctcct aagttgacaa agctgtcaaa gaaaggtttg ttcacgataa
     7801 acggtgcgct atgtccagct gcgattgcat taacgtttgc ttcaatggct ggcgcattga
     7861 ttgtttgcat caaaggatcg accatattcg ctccgtgtaa accaaagaac cataagaatg
     7921 gtgtgataaa tgcaagcagt aaggcagatg gataagagtt tgcaagtccc ataaatggtt
     7981 cttggaccac tgtatagaaa gaacctacga tatcatcaac accgaatgca gcaaaaattg
     8041 cagcaactaa agcaaacgca gagatagtga tcattgctgg tagtaatgaa gcaaatgctt
     8101 ttgcaactgc cggtggcaca ccatcaggca ttttgatgat caatttttca tttccgctta
     8161 aacgtacaaa gatttctgtt gaaataatcc caacaataat agcaataaac aaaccgtttg
     8221 agctcatacc taatgctccg cctaaagcga agaaagagcc taaagaaatc acacctgcgg
     8281 aaacaccgtc ttttcggtag ccgttagcta aatgataagc aagcaagaaa gcaatcaaga
     8341 cagaaagaat ggcaaatgta ccgttccaag cagcagcccc gaatcctttc catgattcac
     8401 caccaaaaat tgagttcatc aattcttgga acccgggaat cggtaagtta ttgatcatta
     8461 ctgctaatgc tcctaagatc attaacggca tactcaccat aaatgagtcc cgaatcgcaa
     8521 ctaaatgccg ttgtgcacca atttttgatg ctacaggtat aaaatgtttc tccataaatg
     8581 caacaaattt atccataaat cttccctctt ttctttactg tagattacgc gttcaatcga
     8641 cgatacagat caatgatctc ttttgctaaa tctgtaaaag ctatagatgt catcagatga
     8701 tcttgactgt ggaccgtcaa aagcgtgact tcaacgtgat ttccttgtgc ttcttgtgtc
     8761 agcatctctg tttgagagtg atgtgcttgg actaaagatt cctctgcatc tttgattttt
     8821 tcatctgcta aagtgaaatc accttttttc gcagcagcaa tcgcttccat tgcatcgctt
     8881 tttgcatttc cgccaaacat gatcagaccc atgatggctt ctagattttt ttgatcttcc
     8941 atttattgta tcctccgata atttttatta tttgtttatt agtttttctg cttggtcgag
     9001 tactttttca ccattcatca tgccatagtc agccatattg attacatcta aaggaatgcc
     9061 tttaggtgct agcttttcag caaattgatt ttgcataaag cgtacttgcg gtcctaaaag
     9121 taaaacgtct acatttttag attctagttg attatccgca tctgaagcag atacagcaaa
     9181 gatgtctgct tccattcctt ttgcttctgc tgccttttgc atttttgtga ctaggagact
     9241 tgtactcatt ccagctgaac atacaagcat gattgttttc ttttccattt taaacacgtt
     9301 cctttctata cttacacttg tatataagca agtagcgtgc caactttaaa agcgctttaa
     9361 aaagttgata tcatcacatt taaggtctat accaagttgc atacacacta aaaaagaaag
     9421 cgcacactaa acacacaaat taatttttat tacctttttt cttttaacgt gcacaaaaaa
     9481 agttgtgaca caaaacttgt cacaactttt ttcaaataaa cggtattcaa aagcttgcat
     9541 ctgcggtaat aagtccaacc aagttaaaaa cataagatgt tgtttttact ttgctattct
     9601 tattacttga tgcaggacag ctttttcaca acctctcaat aaacggtgtt caatcagctg
     9661 accctgggta ttagctcaaa acgctggatt cacaacctct tttatttcaa ataaccagta
     9721 aatacaatga acatctacaa aaaacttcta tttatttata gatttcgtca ggcaaatcca
     9781 attctctctt atcaatcaaa gtctgatacc acgaagcaga ttttttcaat gttctgcttc
     9841 gttcatcgtt caattcgatt cgaactaatc catatcgatt cttaaatgca ttcattggtg
     9901 acacacagtc agtgaatgcc cataacatat agccttcgca atttgcgcct tcttctgttg
     9961 ctttgatcaa gtaatgcaaa tgctgtccga taaattcgat acggtaatca tcttgcacga
    10021 ttcctttctc atccatatac tgttcttcat attctcttcc cataccgttt tctgttatca
    10081 gccaagggat attatgataa ttttctttta gatacatggc tatatcatac atgattttcg
    10141 gatagatttc ccatcccctg gaattattca ttttcttccc aggtaaatca aagacttcat
    10201 aatatcgttc aggatggaaa ggtgtctctt cattccattg ataacgaggg gcgcgaacgc
    10261 gtttaggata atattgattg attccaagga aatctactgt atgatgctga atcgtttcta
    10321 aatcctctgt tgcaggatcg aaataaatcg attgtttttg acacaactcc aggaactctt
    10381 ctgtgtagta tccttttacc atcggatcaa aaaatactcg attataaaac aaatcataca
    10441 tataagcagc tttttggtct tctggagaat tggatcgagc atagaccatt tcaggattta
    10501 aaatacagcc aatccttcca ccataatttc cgctgcggta aatctctact gctttagccg
    10561 ttgctaaaac tttatgataa ttccacatca tccacttttt tgtgttttgt tcatgcggcc
    10621 agcgaacagc atccaaatag caacgcgttt ggggaacgat tggttcgttg aatgtaaacc
    10681 agttttttac cctatcaccg taacgatcaa aggcaatttg agcatactta gcataaaaat
    10741 caactacttt tcttgaagac cagccatcat atttttccaa aagaaaagct gggacttcat
    10801 aatgttccaa acaaatcatc ggttctacgt ctgcttcgat caaagagtcg atcatttcac
    10861 ttatatgctg agcatattct tcatctacta tacagttctc ataatcagta aaaaaacgag
    10921 cccaattgat agaagtccga taatgtgtca gatggatgga tttcatcaga tccacatcct
    10981 gctggtattg ttccataaaa ttagttgcta cggctgggcc atacccatta tgccaaacaa
    11041 aatgttcatt tttataccag ctatctataa acgaatcctg tccttctttt tttcctttcc
    11101 aaccttccgt ttgccaagca gaagatgcag caccaagaat aaaatttttt ggaatagtaa
    11161 ttttcatgat ttcctcctgt tttttagatc ccatcatttt ccacacgatt tgctactttt
    11221 acaaatggca gatagatcaa aatagaaaca ataatacaaa caagttgcgt aataactgca
    11281 ccgatatttc ctgctgttgc cagataagca ttgacgatcg gcggcattgg ccaagggacc
    11341 attacaactg ctttcgccgc aaatcctaaa gcggttgcaa aataaccaat cgttccagtg
    11401 ataagaggcg ttaagataaa cggaatagct aaaattggat tcagcatgat cggcatacca
    11461 aaaataactg gttcattgat gttgaagatc ccaggagcaa gggataactt ggtgatttgt
    11521 ttcatatctt cccgttttcc aactaacaat actgcaatca gtaaaccgat cgtgactcca
    11581 gacccgccca tactcatata catatcccaa aatggcatag taataatgtt cggtacttct
    11641 tttccagctt caaaagcttc cgtatttaca gcaattgccg ctaaaagcaa cggttcccgt
    11701 atcggcttca ccatttgatt tccatggata ccaatcaccc aaaagacttg cgcaataaac
    11761 atcaatagca aaatacccgg taacccttgt acgacacctt ctaatgggcg ttgtacgaca
    11821 ttgtaaatga tatcataaag gtacattcct gtaagttctt tgatgataaa tcccgcagcc
    11881 gcgatacccg atacagtcag aatcgtcggg aataaagcag aaaaactagc agaaacattc
    11941 gttggcacgg tatcaggcat tctcagctgt agtttcttct gtttcctcaa ccagcaataa
    12001 agttcaatag aaaggatgga gaccaacatt cccaaaaata accctttcgt atctgtatat
    12061 tgtttagcca atacgttttc tactataaca gtctgatttt cattcactaa ttcataaaca
    12121 gttggattaa cagataaata agacatcact gcgatgatac cagggaatac accatccact
    12181 ttattcagct tggctaattc gatccctatc agaaaaacag catagatggt caagaaactt
    12241 agtgtgacat agctgatggc agatgcgata ggctttaatt cttctaaaaa acgcaagaaa
    12301 cttatctgtg ctaagccatt ttccgagtca aagaccattg ctgaaaacaa tgtgccaaaa
    12361 gcacccgtaa taattaccgg aatcaatgca gcaaatgcgt tttttatcac catgatatac
    12421 cttaaattat tgattctcgt tgccacgttc cctaaaacat tggctaattt atccataaaa
    12481 ctcattccag atcccctcat tcctgcttct tctccttgac gtcatctctt tttgtctatt
    12541 agtcagcgct tacatttcga tgaacagaaa ctatttactc ctctttttta ccaaatataa
    12601 aacaaaaatt catctgatgt atttatcata aaatacatca gatgaactgt caattagttt
    12661 ctttttctcc tattattttc tgtaattctc tccgatttat tgccatatgg acagtcattg
    12721 catcaaacgc agcaagtgca ttccgccttt cgatggcctg aacgatctct gtatgaatat
    12781 cgatcgtctc gattttcaga tgctggatat cataattttt attaaacaaa gcaattgatt
    12841 cattaatgat tgggataata tgcagcaagg ctacgtttcc gctagcttct gcaatcatcg
    12901 tatgaaaatc gatgtctaat tgaacatgtt cttgtgtgcc ttctcgaaaa gaagtttcaa
    12961 tcttttgcgt taattttttc atttggacga tttgattctt cgttgcatat tccgctgcca
    13021 aacctgccat cttaggctcc aataaatatc tcagttcaaa taagtctcgt atcatccgat
    13081 cctgatcttc aatcaaagaa aaaccgagtg ggtcattggc aatccctcgc ttatcactga
    13141 caaatgtccc cgctccttgc cgaacttcaa ggatattcct ggaagctaga gcccgcacag
    13201 cttctcgcac cgtgcttcgc cccacctcta aataatcgga caattcatat tcattcggca
    13261 gtttatctcc tacttgcaac tgcatttcct ttaaatatct aaggatcttg tcagtagtta
    13321 cttctactag ggttttattt tcttccaaac cacatacctc cttttcatct gatgtatttt
    13381 ttcgtaatta ttataacacg tttgaatcat ctgatgattt tttgtataca aaattgatta
    13441 atccgttcat agacatacaa acgaagaaga tatttaccat aaaaaagact aggataaaat
    13501 tcactcctag ccttcgatca tttttatttt gaacgacaaa aaatatgatg ttcaataaca
    13561 gacgatcttc attcgattct tgatgtcatc ttttgttttt tttaatatat ggataaaaag
    13621 tttgattaca tcgtttctat tctagaattt ggtcgattct caattcttct tctggtgaga
    13681 aatctaaatt atccatcatt cgaacacttt cttgtaactg acttaaccga cttgctccga
    13741 ccagtacact tgtaacagat ttttgtcgca aattccatgc aagggccatt tgcgctaatg
    13801 attgtcctcg tgatacggcg attgtttgca gtgctttgat tttttccaga gttgatccaa
    13861 cttgttcttc tgaaaggaat ggtatttcct tacgatgtgc tctagaatct tcaggaatac
    13921 catgtagata acgatttgtc agcaaccctt gagcaagcgg actgaacgtg attgccccta
    13981 gcccttcttc ttctaatact ggagatagat cgtcttctag tagtgcacga gaaaacatat
    14041 tgtagcgcat ctgatgaata atgaacggtg cttcctttct ttttaaaatt tcagtcattt
    14101 tttttgtatc ttctccatta tagttggata taccaatata taatgctttt ccttgtctta
    14161 caagttgcat caaagcttct gctgtttctt ccaaaggtgt atcagggtct gggcgatgat
    14221 gatagaagat gtcaacataa tctagcccca ttctttggag actttggtca caacttgaaa
    14281 tgatggattt acgagagccc cattccccat atggcccttc ccacatatga taacctgctt
    14341 tgctagaaat aatcagttca tcacggtagg cttgaaaatc ttctctaaaa atacgcccaa
    14401 agtttttctc tgcagctcca gcagggcctc cataattatt cgcaaggtcg aaatgggtaa
    14461 ttcccatgtc gaatgcgcct cttaaaatct ctctttgatt atggatagga tcataatcac
    14521 caaaattttg ccataatccg agagataaaa tcggtaattt caaacctgaa tgaccggatt
    14581 tacgatattc cattttttca taacgtgcac tatctgcaat atacaatttt tctcctcctc
    14641 atcaaatctt tttaaaacgc tttctttttt ctatttttag tttactacat tttaaagaaa
    14701 aggagttaat caaaatgatt ttttcgtata tttttttgcc atttgttttt tactcgttga
    14761 tagatcagaa attgattacg tgcttgctgg atttttttat aacgtttcgg ttgttttttg
    14821 taaaattgct gatgatagtt ttctgctggc caaaacgtac cggctggttc gatttttgtg
    14881 acgattggtt ggtggaaagt tcctgaactg tctagtttct gttttgattg ttccgctaat
    14941 tctttttgtc gttcgacttg ataaaaaatc actggacgat attgcttccc tctatcttga
    15001 aattgtccaa atgtatctgt gggatcagta atttgccaat agattgtcag caactcgcta
    15061 taacttattt ctcttgtgtc ataaatgatc tccacagctt ccacatgacc tgtgtaacca
    15121 ccacttactt gatcataatt tggtttttca acatgtccgc ccgtgtatcc tgacaaaaca
    15181 gataggatcc cttttttcga ttcaaacggc tcgaccatac accagaaaca tccccctgca
    15241 aatactgcac gttcttgata gtcagcatct tgcatggcat gcttggaaaa gtcatatttt
    15301 tgctccttat caaatccttc cgtaatcaat aaataaaagt ccattacatc aggcgtcaga
    15361 ttcattcgga tagctaatgg acgtagtgtt gcttctagtt ttgataactg ttctttaacg
    15421 gatatatttt ctcttatgtc attctttgtc tgaatcaata cttttcgttc ccaatctcgt
    15481 gtattcggat tcaaaatcag attataaagt gtttgaatga atatttgttc ctcatccata
    15541 gattctcctc ctttccgaag aagacaagct agtgacttta gctgtaattt atcataaagt
    15601 gaggaaataa gcgattactt catcccccta cagatttttc gtataaaaaa gagagaatcc
    15661 ttatcgacag attctccttt ttaatcaatt tattttataa atgaaaagtt aatttacctt
    15721 ttatggaaaa ctattttaaa aaataaacat aaatatgcag ttaatgtaac aagataagaa
    15781 ataatagtcg ttactgtata acttgtgctt actttaatat cagcaactcc tttgactccg
    15841 cttatttgta ccaatccatt agcattcacc tgctccttta caggttgatg atttatttct
    15901 acattcgttc ctaaataagc atatacagga agtgtgatta cttggctctt ctcattagtt
    15961 actctatata tgatagaact accagttgtt ttataaggaa ggtttaccca ttgactgcca
    16021 atctttgctt cgtgttttat tatatgctcc ttattctcca atgaagcgat aggagaataa
    16081 tcatataaaa aataatccat tcctttagtg gtatacgcct ctactgtttc tttgtttaca
    16141 acaatatgtc ccggctgaga aattattttt tgattgaaat tttttttact agaaacagtt
    16201 aaagtgatta ataacaaaac agtcataaat aaataaaata gttctcttgt cttattgtat
    16261 cttctatttt tgaaaaatat catcgttaat atcagagaag agaatattat ttgcaagctt
    16321 aagatccgcc aaggaaattg taacaatttg gctggcgtat tttgcagaag ataccatggc
    16381 accaaactag ttgtagctag ccaagtcaaa cacgtaccat aataaatctt tttttctatg
    16441 tttgttaatt ttttaaataa aatcagggga atacataaag ataacagacc aactagtccc
    16501 attgagtaag tagttaagtc gttgttcata gcttcagtca gactatcgaa cacattagat
    16561 gcatgagcat ataaatttgt cacgctaggt ttgttgattt tttggtagag catttgttca
    16621 aacatcggat accaaaaagc actcgtcaga accaatgtca ttcctgccgc actaaataat
    16681 tttttaaata tagcaataaa atctgcattc ttgaaacctt tagaaaccaa acgaataaaa
    16741 ataaaaatga taattaatgc tgtactcatt aatgttgata gtacatggct gtacactagc
    16801 aaactcatac tcaatgctag ctttacagac ggatactttt cttcttttcc agagatgatt
    16861 tgataagcat aaaataatac agggataaca agtgttattg cgatagcttc ggcaattgcg
    16921 gaacgatagt agatgtctac tgtccgataa gcagagaaaa tatagagaca actaaataaa
    16981 aatgccgctt ttttttgttt taaaaaccgc tcgccataat gataagctac gagtgttgta
    17041 cacaagttca ataaccaaac gtaaataata tagcttacaa tcaaattttt tgtcatccaa
    17101 tataacatta cagctggaaa aaaagtcaga aagggataaa aataatttac accatatcca
    17161 gtataattga atgtctcata attaatcgga ctggtaaaaa tagtcgataa ccccttgatt
    17221 cgagataagt gaaaagaaag atctccagtg gtataaatac tctgtgtatt tttgaaaaag
    17281 atgaaagaat atatactact aactataatt aatccactca atattactac ttttttattt
    17341 attttcattc ttcttgttta tctccttttt agtcacatat cgagaatctt tcaacttatt
    17401 aggtgcaaat cgtttaaaac ttgaatacac cactaaacaa taagtcagaa tactgatcca
    17461 taaagccatg agagcagttg gagtatattt tgttgtaatt tctatcttat tttctccagc
    17521 atttacatcc acattcacta agccatgttt tttataagag tcatttacga ctttaccgtt
    17581 tacttttacc tgtgtaccta aataagcata tactggtact gtcacttttt gctttttgtt
    17641 gcttgccact gtgtaagtaa tgttattatc tgcagcttta tacttccctt tttcccacga
    17701 ttctcctact tttacttcat gtttttctaa gtgaggcctt tcttttatcg cttctgttgg
    17761 ggcgtaatcg tataatcctc ccatatctga tgttgtataa cgtgggagtg tttcttcatt
    17821 gataacaata tgaccgtgtt ttgattggat aacttttgcg taattttctt ttgctgctat
    17881 agacgtgacg agtagaaaca ccacagtagc gccaatgatt aaccatgaat attttttatt
    17941 catagtcttt ttcataaaaa caagcgttat gatcattgaa gaaaaaaaga tttggatacc
    18001 taagatacgc caaggaaact ggagtaagct tatcggtgtt ttttgaaaca aaaaccatgg
    18061 aaataaatta gttacgcata cccatgtaga aactacgcca acatagatga ttttttcttt
    18121 tttctccatt tctttcagta tgaataaagg aaaaatcaac gcaaccaatc ctaataaccc
    18181 catagtgtat gttgtaatat cgttatttaa cgcttgaatg atactatctg aaatagaaag
    18241 tgcttctagc tgcaaatctg ttttgaaggg actgtgtatt tcttgataat tcatctgctg
    18301 caacatagga taccaaaaat agctagttaa tgcacaagtc aaaaaaacag cctttactaa
    18361 attcacgacc acaaatttta tatcgttttt tatttgcttg cttaaaaaca aacgaactat
    18421 aatcatacaa gcaatcaatg cactacacaa tagtgtagtt aagacatgag tatacacaag
    18481 tagacttata ctgacagata aagcgatgac ttttttttct ctattgaata tcaatccata
    18541 agcataatat aaaacagctg ggataatcgt aagagcgatt gcttctgcaa ttgcggatcg
    18601 ataatagata tcaactgttc gataagttgc aaaagtatat aaacaactaa ataaaaaagc
    18661 agcatctatc tttttaaaaa acttttctcc ataataaaaa ctaatcagaa tcgtacaaat
    18721 atttaataac caaatatata gaacataact taatattaag ttatttgaaa ttccataaaa
    18781 aacgactgca ggaattattg taagaaaagg ataaaaatag ttcagtccat ctccataatt
    18841 gttaaatgtt gtatagttga ttggcccttc aaaaatagaa gataaccctt tgattcgtga
    18901 aagatgaaaa gataaatcac ctgttgtata aatttcttga gcatttctca taaaatttac
    18961 tgaatataaa gtactaagta agataagaac tactaaaaga aatgcttttt tacttatttt
    19021 catagatttg ttgttctcct tttttaattc tattttcagt atactagaat tgtctttttt
    19081 taataagttt tgcgttaaat ttttcatagc actagtatga tatactagaa aagaatcaat
    19141 ttttattact tttaaatagg agaaaaaaat gaaaaaaaac aaaaaccaaa taatagatat
    19201 catttttatg ttatttctaa gttttgctta cgtcatccct ctattcatgt ctaagggaat
    19261 ctatcatagt gtcaatcagg atacttactt tcatttatct cgaatcatag gactagataa
    19321 tgtatggagt tctccagtaa acttcaataa cttcgatcat catggaacaa tgatgaatat
    19381 tttttatcca tggcttactc tttatccagc ttttttattt tataaaatga tgggaaatct
    19441 tgttttaagt tataatatct actatttttt tatcactttt ttaacaatgg tcgtttctta
    19501 tttttctatg aaacaaataa aaaacaatcg ttatatttcg ctgttatttt cgattattta
    19561 tacattttcc gcctatcgtg ccattgacat attccatcgt gcttcattgg gagaagctgt
    19621 cgctttaaca tttttgcctt tgatactaat ggggtgttac gaaatttata ttagagatta
    19681 ccaaaaatgg tactggttgt ctattggcat gacgctagta gtgtatactc atttactttc
    19741 tgtcgctatg gtttctgtat ttattggagg aacgttgttt ctttcttttt atttttggga
    19801 ccaaaaaatc gctagactct taagtctttt aaaagctacc gtcctcacct tttttttaag
    19861 tgcgggattc ttaattcctt ttattcaaca atctagagca caagaattga aagtcccact
    19921 gggaaaagaa ttaagtggta tggctcctag tgatatgctg acacatattt taaataataa
    19981 ctataacaac tatactattg gattattctt atttctcgga ttgattggtg cttttatttt
    20041 tataaaaaaa ttaactgctg atgatttatt tattttcttt cttggtgtat ttgttctttt
    20101 ttgttcaacc aatttatttc cttggcaact ttttaaccat acaccagtta agagtctaca
    20161 atttgtctgg cggttaaatg gtttttcttc tttatttata gcctatacga tgagtatagt
    20221 gatctattat attttttcta ctaaaaataa ttcatggaaa ataatggtct ttacgtttct
    20281 tgcactaata ttgcatctct caggagtaag caattctatc catgctaaca aagattcatt
    20341 aacacttata gcacctgaag acgctgttgc tatagctgaa aattacaatc atactgatta
    20401 tgcaaacaaa gagtcaatct atcatcctga tatgattaat aatgatcaat atttactagg
    20461 taaccaggaa ataaatccaa caactcattt tatgagtaac aaacttacaa ttgaattaga
    20521 taattcgaat aataaaaata ctgtcttgac gacacctatt tatcgttata aagggcaagt
    20581 ggcttctatt aatggcaaac tagtacaaac aaaattatct aagtttggca caactgaatt
    20641 aactattcct ccaggtataa ataaagtcgt tattacttat cagtacacaa aactagcaat
    20701 tgcttcaaga tatttatcta tcgttacttt gattttattt ttactttatc gatttacttt
    20761 ttctaaacaa aaacaaccga gaagagaagt acaacattct cactagattt ttatttaaga
    20821 aagacttttt agctgtacac ataaacaggc taaaaagtct ttttttatat ttctttaatt
    20881 tgcttcatac attatttaac atcgatattt atactgtgaa acatgcgttt catccattat
    20941 caaagtattt ttatcgataa taaacttcat ccaaaaacag accttgtgca gggacggttt
    21001 ctcctgcatg ttgccgcact ttgctttcaa atatttcatc gattgtttct atcggcatgg
    21061 cacctgtgcc gatttctagt aatgtcccca tgataatccg caccatttta tataagaatc
    21121 cgtctccgac aaaagtaaaa tgaagcattt ctccctttcg ttcgatagat aattcatcaa
    21181 tcgtacgcac tgtggatttt tttgattttt tcaatgcaga aaaaccaatg aaatcatgtg
    21241 tacccactaa tttttcgcaa gctgcattca gcttgtccat atccaactct tgagggaaat
    21301 aaaagctgtg gtttcgctca aatgctgaag gaatcacgtt gttccaaaca taatagctgt
    21361 attttttgcc caccgcatta tatcttgaat ggaagcgctc aggcatttct tcgattcttt
    21421 tgatgacaat atcccgcgga aggtaacgat tcataaagtc gatcatttct gccagtccaa
    21481 tttctgtgtt tgttttaaaa tttgctactt gtcctcgcgc atgggtgcca gcatctgttc
    21541 ttcctgatcc aataatttct atctcttcat ttgtcatctg atgcaatact ttttcgattt
    21601 ttccttgaat ggttttatcg tcatctccaa gtctttgcca tcctgaatat ctttttccgt
    21661 catattcgat tgtcaacttg atgtttctca tattttagtg gctcctctgt cttccatttg
    21721 gtcttctctc taccttttta agattgtagc acaaaatata gctccttgct tctctaagac
    21781 agaagctata caagaaaact gtggaaatat atatttcaga aaaacaaaaa acagccaccg
    21841 gatgaagtat ccgctgactg ttcaatttga cggctcaagt tttactgttt gagatgcaag
    21901 atactcaacc aggcaatggg cacataatta aagaaaaaac tgattctttg gcaaaaacct
    21961 attttattca gtaatggcca agaatttata gaaggaattc ttgccagtcc ataaatcgcc
    22021 gcaaaaagca aactgatcac agacagtcca aggtataagt ggcttacgtc catttgccca
    22081 ttttttcgat agatcaagaa aagaagaact ggaaacaata aaaaaccact gtaacctaaa
    22141 cctgatccga tattatggac ccatgtcgag acattccacg aagattcatg ggtattgata
    22201 ctgaacaaac ctgtaaagat acaatcacct ataccataga acgcgatggc tgctgtaact
    22261 agggtagcta acacacgaga tgtactaaca aatgcagcat acaatgcagg caatgacagg
    22321 atgaaaaaga tccctgaaac cacagaccaa ataagaaacg cttttcttac aggactggaa
    22381 acctctccaa atacactgat cacgctcttc atttgatcta attcaggata atacaatcct
    22441 aatacgtacg gagtcaaaaa atcactcagc acgcctaata ataaaaagaa aaaaccaaat
    22501 ttacgtaaaa aatccatgat acgcctccaa taacaattac ctatgctttt aattgttatt
    22561 ataaacgact ttatcttgat ttaacagaaa cctctattta cacgaacatc tatataactc
    22621 attaaaaact cgaatcattt taaaaatact aaatatctaa cgttcaacgt tcacttaatc
    22681 catctaaaca atctttcaat ttgatttttt ccccacttct tttacgcgcg cctagctctc
    22741 ctattgcagt aaacaacaga tcacttgacg aatttaaggc agtttccatt gaatcctgga
    22801 taacaccgat aataaatcca ataccgacga tttgcatcgc gacatcatta gagataccaa
    22861 acaaactaca tgctaatgga atcaataaca gtgaaccgcc cgcaacacct gaagctccac
    22921 aagcagctaa agcagacaaa atacataaaa ggactttcaa aacaaaaggt gcttcaatcc
    22981 ctaaagaatg tacagcagtc aacgtcatca aggaaatggt aatcgcggca ccgcccatat
    23041 tgatcgtagc acctaacggg atcgatatgg aataagactc ttttgtcaat ttcaatcttt
    23101 cagccaacat catgtttatc gggatatttg cggcagaact tcgggtaaag aaagcgggaa
    23161 gtgcgctttc tttcaaacaa aagaaaatca atggataggg attttcttta ataaacaaaa
    23221 acgtgaggaa tgggtacaca actaatgcga caaacagcat cgtaccgatc aaaacaagta
    23281 aaagctgcag atactctgcc aatccagcga ttccagtcgt agcaattgat tgataaacca
    23341 atcctaaaat ccctatcgga gcaaatgcaa taatcacttg tacgacttgt gacaacgcta
    23401 tagatatctg atccaccaac tcttttgtcg attctgaacg tgctcgaaaa gctagtccca
    23461 acaatacagc ccagaataag acgccaaggt aattcgcatc aataagagat tgaacaggat
    23521 tttgtgtgac attcgtcaac atagtagata aaacactttc caaactttgc ggtgcttttt
    23581 cagatactgt ttcttgtaaa gtaataggaa cagtaaaaat tgaacttaca ataactgcta
    23641 caagtgcaga aagcaatgtt cccactaaat ataagatcaa aataggcttc acgaatgtct
    23701 tattcccaat tttatgcttg gcaattgacg ccatcgtcaa gaaaaaaacc agaataggtg
    23761 cgattgcctt caagcaactg acaaacaacg ttcccaatat tgaaataaat gtccatgtgg
    23821 ggaaaaagat accaaacaat attccgacta aaataccaac aacaatacgt tgaactaacg
    23881 acatatccaa aaacttctct aacaaatgac caccctttca caattttaac aatcattgta
    23941 tcattttatg caaagaaact aaaggtataa ttttctaaaa attctaacaa tacaaacaac
    24001 catttcttgc taattttgta ctttttctgt ctacacgttg ttttttgaga tattctaagt
    24061 taggatgtta ttaatgggca acttatcagg aaacgttttc ttatgttttt gtccaatttt
    24121 tttgtgaggt gtttattctt gaaaaaaata aagaaggaga gttatggctt cctgacaatc
    24181 tttgtcgctt gtataatgat ggttttacag cgtatattga tttcagcagt cactattcct
    24241 acatatgcaa caaaccctgg tcgattctac atctatacat ttttacaaac ttccgttgtt
    24301 attggtgcaa atttgatccc actttacatg ggttaccaat atcaaaaaat cgcccgttta
    24361 aaagttttac attatttaag tcgttttgcc tttatattcc taatagccac actagtttgc
    24421 aatatctttt tttacgtaca agctggcagc ttgaatattc gtgattattg gcttatccta
    24481 acacctatca gtcagaatta ctttacttat gctgtttctt gtactttgct tttttgtagt
    24541 attccttata cagttggatt tttaaataaa ttatcgaaaa caacaattaa atatctacta
    24601 ttatttttaa caattggatt agttggctgc tctactctat ttaataaaga cccgtttgca
    24661 ttacagaatg gacagagtat tttatggatt ttttatttat ttttaatggg ttatggtttg
    24721 aaagaatgga actggaaaga aaaggtccgc tataagcttc ctcaagtatt tatcagcttg
    24781 attgttttat tcggtttgat tattttgatg acacaaattt cactcatcat cagaggaaat
    24841 acagatacag cgctgaggtt ttctaaacca tattctctct tcgcaatgta ttatactttc
    24901 tcttcgtttt tatttttaga aatgctatct gataaattag gtataaaagg aagaggaaat
    24961 tttcttgctg tatttttgat tgtcactcaa gttatatgta atttcccttt agtttcttat
    25021 cgcgtatcta catttatgaa acgtgaattt ccaaactcag ggaaggcatg gctgataaat
    25081 atcgggcagt tttttatttg atatttatta gcagtgtccc tcctagttat ctttttattt
    25141 tatatacaaa aaatccgttt cattcatcgt ttcatcgaat acttcgcttt tgattcgatt
    25201 gaacaattaa ctcagcgttg gaaaaaaaga attcattggc tttttgttca taaaagttat
    25261 tttttagttg cagcattttt ttactgcttt accttcgtgc agattttcgt tttagaacca
    25321 aaagaaggtt ggaaagaaac tatccaggtt gccttaaaaa tatttactca gcgacaagca
    25381 cccatgatcc tgacaatcat cattattatg ggatttttct tcttactatt gttgatttcc
    25441 aatcgttttt ggtacgcctt gactgctacc ttgatcatta acttactgct cactatttcg
    25501 acagtaatca aaatggaaat gcgggaagag cctgtctttc cttcagattt aaaaatgctg
    25561 accggattgt cagaactatt atcgatggtt agcccagtct tattaatcgt gggcggattg
    25621 atccttctcc tattattgat tactagtatt attgtacaac gtagactaca aaaacagtat
    25681 tccttgaaga ttcattggaa acgtcgattt atcagtatcg ctgtattatt aggatgtttt
    25741 tcgggtgtct ttttcattaa tcacaaaaat tcgccttctt tcttgctgtt taatttattt
    25801 aaagtaaaca agactttctt taaccagcaa ggcgccgtaa aagataacgg accagtcatt
    25861 caattcctaa acaatatcga cattaaaatc atggaagaac ctgctggcta ttcgaaagaa
    25921 aaaattaatg gaataatgaa aaagtacaac acaaaggcag atgaaatcaa ccaaacaaga
    25981 agtgactggt taaacaatca gacgatcgtt ctcaatttaa gtgaaagctt cagtgatcct
    26041 gcacgtgtcc ctaatctgac agtacctaca gaccctattc cttacatcaa aagcattata
    26101 acagaaggaa caggaggatt gatgttatcc gtcggttatg gtggcggaac agctaacatg
    26161 gaatgggaag gactgacagg cttgagtatc agtaacctgt ctgcttcgtt agttacacct
    26221 tatacccagc tagtggagcg tcagaaaata agtccaaata ttaccgatct attcgatgaa
    26281 aaaatagcca tccatccttt tacagctgct ctttatcgca gaaaacaagt gtttgataaa
    26341 tttggttttg acaggttcta ttatttagac agtccggata aattaactta tacggataaa
    26401 atagaacaaa gcccacgcat atcggatgat tcagcataca aagaaacctt gaaagcttta
    26461 caaagcaata cggaaacgtc acaattcatc caattatcca ctatgcaaaa ccatatgcct
    26521 tatgatgatt actatagtga attgaactac actgctgaag gaactgctgt cattcctaat
    26581 agaagaaaag aattacaaac ttatatgcaa ggccttcact ataccgatac agcagtaaaa
    26641 aaattcatcc aagaaatcga caaaatcgat aaaccgatta cctttgtttt ttatggtgac
    26701 catttacccg caatctatag tgggaatgat tcgaaaaaat atggattaga acagcaccag
    26761 acagattatt tcatttataa caacaagtat agtcgtgaac aagcagctac gttaaataaa
    26821 gaagttgttg ctcctaataa ctttggtgct atggctcttg agcatgcgaa tatcaaagta
    26881 actccttact atgcgttgtt gacagaagta tctaatcatc tacctgcatt aacaattgat
    26941 cctacagaaa gcttgtctaa tcgttttaat ggaaaacagg tctttgttac agaggatagt
    27001 caaattatcc aagaaaaaaa tttaactgag aaacaaaaag aaattctaga agattatcgt
    27061 ctgatacaat atgatcttgt tgcaggtaac cagtacagtg caacatgggc gacacaaaaa
    27121 ataaaagact aacaaataaa ctgagcaagg ggttgtgata aaagacatgt cacaacccct
    27181 tgtttatctc attaatttgc ttgtccataa acgatttgat taaagccatt tttcaattca
    27241 ttattcgctg tctcgttgaa gtaaagataa ttatcgggat tcccctgatt ttgttgtgtc
    27301 accaatactt ttggctgatt ttgctgaaac ccgaatagat agacgtgctt tttcagatat
    27361 ggttctgtct ctgcatcgga atagacggct gtgatttgat agtctgcttg acctgtccca
    27421 ctttctgacc attctgcaga aacaggcact ccaccaatag ccatcttcca ctccccgttc
    27481 aaaatagctt gagggacttt aagaccatat aagtccacac tcatttgatt cgtataactt
    27541 ttgtattgtt gtcccattgt ttggccccat ttggtcataa atgcctctaa ttgtgcggat
    27601 ttgtctgcat tccacagtgt ttgttcaact tgttcgctgc tttctgaaga ggaagatgaa
    27661 gcctctacag aagaacttga agtagatgtt tgagttgttt cagtcgtttt ggaagactct
    27721 gacgaagtag aggtatctgc tgtttctgta cttgctgcag ttgacttgct ctctgtgcta
    27781 gttgttgtag tagttgcaac tgttgctttc gctgtttctt ttgttgattc ttttttcgat
    27841 tcattcccgt tggtacaacc agctaacaaa aaagctagac caattgttac taaaatcctt
    27901 tttttcaatt aaaaaactcc tttcgattac tcccacttct ttattctatc aaataagcaa
    27961 tgtgatttta ttgatttttc gtattttctc atcaatcttt caaatcttct aaaaactgag
    28021 aagcacccgc tgatgttgtc tgtaatacat cagcgggtgc ttcttttatt ttaatcttcg
    28081 tgattttcca atttacctca cgctttatat ttgtatttga agaaacatag acttttagtc
    28141 atcatcgtct tcctcatcca aatcttgtcg gacagttttt ccttggagtc tttgtacttg
    28201 gtagatgatt tctttattga aacttaaaag ttcaacaagc aattgttgca agccatattt
    28261 ttcttctttt tcagctaatt tgattgcccg tgtgataaag acattttgga aatcaaaatc
    28321 ttttgcaaag ttttccaaca ttgttgaggc tggtaaatat ttgttttgac catgttcgta
    28381 aatttttcca taacgcatga cttcttctaa agtagacgga acgatttcat tttcaatcac
    28441 taactcatga gagattttat tgaaccatct cgcttcttga tcagcatatt ctgaaaaaag
    28501 ggtacttaat tcttgcgaag atgtacccaa aacatacaat tgtgcttgga tcaatttcat
    28561 ttcttctaat ttaaaatttg ctaatacatg ccccaccatg gcgccagcag ttggtttatg
    28621 atggtcgata tctgcttgtt ttgtttcttg aacaaatttt tcttccacta tattcattga
    28681 tttacgcctc ttttactttt gctgattgga cttcataacc taatttttcc acaactgcag
    28741 ctaattgttc agggtggact tcatctggat caaagtttgc tttgattttg ctcgcattaa
    28801 acaaaacttt cgtattgctt accccaggct gttgagaaac cgcatgttcg attttttgca
    28861 tacagcttgg acaagctagt gtatctaatt gcataataat ttttttcatc gtagttcttc
    28921 cttccttttt cttgatagtc ttattctaga ttacagcttc cataaaaaaa ttgattctta
    28981 tcaagtttta cgatttttct tctttgcttt cgtgtccaaa atacaataaa cgcatcgcgt
    29041 taaagataac gatcaagata ctagcttcgt gaacgaacat cccactagcc atgtaaataa
    29101 acccggcaaa taagccgttg agtaaaaata agacgacacc aatggcaatc actacatttt
    29161 cacgggtatt taaaacagtt ttcttagcca agcggtaggc atgaaccaac gattcaaaat
    29221 tagattgcat caagacaacg tcactcgttt cgatagcaac atccgttcct gatcccatag
    29281 caatcccgat atcagccgca gccaaagagg gagaatcatt gattccatct ccaataaaag
    29341 caacgcgcaa tccttgttct tggtattttt tcacaaattg aaccttttcg tctggtaata
    29401 attcagcatg gacttcatca atgcctaaca tatcagctac ataatcagca gtcatctgat
    29461 tatcacctgt cagcatcact aactgttttg ctcctgcttg tttcaactta gctaattgtt
    29521 cagcgacttc tggtcgaatc acatctgaca cacctatgat ttgagtgatt tttttgtcga
    29581 ttgctacaat aatgaccgag ctgcctgttt gttgtaattg atgtaaatct tgtacttgct
    29641 ttggtgtgag agaaagtttg tgagcggcaa tcaatttggt gttgcccgca caaactgtat
    29701 gaccatcaat ctcagctgtg attccttgtc ccttgattgt ctgattatct ttgactgcta
    29761 attgttgaaa atcaatgtct ttctcctgag cataatggat cacggcgcgc cccagaggat
    29821 gatcggataa cgtttctaat cgagccacta aagctaagct gtccccttca tcctctgtat
    29881 agttcttgat agtggataca gcagtagttc ctttggtcaa tgtaccagtt ttatcaaaga
    29941 caaaagtatc gattttggaa aaagtatcca ttgcttcacc gcctttgact aagatgcccc
    30001 gtttcgctcc attaccgatt cctgctacat tcgaaacagg cgcaccaatg actaaagcgc
    30061 caggacaacc aagaaccaaa acagtgattg ctaaacgaaa atcacgacta atcagaccaa
    30121 caaccaacgc aataagtaaa acggttggag tataatactg agaaaatcga tcaatgaatt
    30181 tttccgcatg ggatttggta tcttgtgctt cttctactaa ttcgataatt ttggcaaagg
    30241 tcgtatcatc tccgacctta gttgcttcaa tcgtcacgta gccatctgct aaaatcgttc
    30301 cagagaagac ttcatctcca ctgattttga cgacttgtcg tgattcacca gtcactgcgg
    30361 cttcatccgc ataccctttc ccgtcaatga ctcgtccgtc cacaggaata gctccaccag
    30421 tttttactaa gacgatatcg ccttcttcca cgtcatcgat ttccacttct tcagtcgttc
    30481 catcttcttg gacaacacta gcagtagatg gggccatctc ggtcaaagcc ttgattgact
    30541 cccgcgtttt ggtcaatgtt ttttgttcca gatagctacc aaacaaaaac aagaatgtaa
    30601 cgatagctga ctccttgtat tctccgatca taaaggcacc aagcacagca atagtaacga
    30661 gtaaatcaat tgagataact ttgactttca ctgcctgata cgcatggatc ataataggta
    30721 tgaccgcaat aatagaagct atggctagag caatgttata gaacaagaca aaaccagtaa
    30781 attttccgat aaaaccaaaa ataatcaaca cagctgataa ggcggtgata tgatttcgat
    30841 gctcttggat ccacttttgt aatttcatct ttctccctct tttcctttca ttcttacgag
    30901 actaagtata gatacttatc catcataaaa aattgaccac tatcaagttt agtcaaaaag
    30961 gcggttttct tttggtagaa tacactacaa aaaatagtta gcaagaagac tcactaaaag
    31021 tgatcttgcc aactattgtc gtttctatcg aaattttcat tgaatgattt tcctgtacag
    31081 catacatcgg agatctattt ctttatctaa gatttttatc ttgctaattt tttcctttag
    31141 tctttcaaat ccacgtcgtt catagaattg atacgtacag ccactatctg taaaaaggaa
    31201 tatttctttt cctttctctc ttttttcaaa ttctgttagc aacttggtac cgatgccttt
    31261 tgttttcaaa tcaggatttg cagctaaaaa aatgatctct ccatctggcg aatgcttctt
    31321 taaatatgct gcaagcattt gttcatttgc tgtctcgtaa gctcctttac tttctttagc
    31381 aaatatattt tgtaaaaaat cgaatatctt aacatatatt tgctgtccaa aagaacgatg
    31441 tttctttttt tctcctttta tctccgccag caaaacacct gccaactcgt cctctgcata
    31501 caaagcaaga atttgagttg ctcgattcaa ctccatatac aaaaaatatc ttccgtaaag
    31561 attcagcaga agttcatttt ccatatatct ctcaaagttc attccttcaa cagcaaaata
    31621 gatagctttt ttgtaatctt tcttttctaa gggtttaaaa gttagtttca tcatttcgcc
    31681 tcctcaactt caatgattgt gttatactta cattataata gacacagtgt ctactatcta
    31741 taatcaatca tctataagtt tgtcgattaa gcgacagctt tgctttgata tgtcggataa
    31801 ggagataggt aaatgaaaaa gacagataga cgcgtcaaaa aaacagaaaa agctttggct
    31861 gaaacactat ccacattatt agtaaataaa aagattcaag caatcactat acgcgaacta
    31921 acagaaacgg cagatgtaca tcgttcgact ttttatacac attataagga tatctatgat
    31981 ctatatgatc aattagaaag caactttttt cgggatctaa atgaaattct ctcttatgat
    32041 ccagcccata gctatgagga actatacact cgcttgattg actatgttta cgcaaatact
    32101 tttttatatc gcttatttat cctcaaccat ggtgatattt cgtttcagaa gaaagttaaa
    32161 caagttattg aagaaaacta tctgaacata tggctatatg aagacaagaa aacgattatc
    32221 acagaagaaa tgagattctt tactacgtac cacgtccaag gttgtctatc cgttctcaat
    32281 cggtgggtag aaagcaatta caagtactcc aaaaaagaat tattagaact cttacagaaa
    32341 ctgaatgatc acatagagaa aatcatgcct tgaataaaaa catactaagc ttagttaaga
    32401 agaaccgtaa ccttctcgta taacaactga atcttattta gccaaattgt ttactgaaga
    32461 ttttttgagt aaaatttcta taattcctac ttattgaaaa gtagtttgta gtgctgcttc
    32521 tccctctcta agtgatatat cttgttgtac caatcaaatt cacctcatca ttaataaatt
    32581 acttttaggc taatttatta caacttatag gttgaagctg taaccaattt atagtcatat
    32641 tatattttta tcatccagtt tattgaattc ttctcgttta cctcaattca ttttcaaggg
    32701 gaatcagctc atcatctaac attttacgcc atgctcgctt catttcttgt gggtatttaa
    32761 atggtttcgc ttctggatgt ttggctttat atccttcgta atccttactg ttgataattg
    32821 ctttcatatt aggaattgga tcttcacctg gcatatattg cagattagaa gcatgtaatt
    32881 ttttctcaga aacaaaccac tcattggaaa agacatgaat caaatcatca cttacttgtg
    32941 taaaatagcg acgtttaatg acaaagatat cttcattgct atctagtgta ccttcatttc
    33001 tttgtgctta aattcaaaga taattttctc aataaagatt tttgattcca gtaagattcc
    33061 tttactcctt ttacaacata gcgttgtcct ttgttttgaa acatcttctt cccctctttg
    33121 ccattaaaaa tagcccaatt ctctataaag aagattaagc ttcattatta taatataaag
    33181 tttaaatttg gtttattact tactttttct tattctctag taagctaata ttgaaaaaaa
    33241 tgtaatcaga tcattatttt tatatgttgt aacttcctga taagaaaact aattaaaaga
    33301 aagaggtaac tacataaact aattaaaaaa gctaacttca tagttggagg ataaatggaa
    33361 gaaacttcaa tgattgtttc tccttgtgtt ccttcaatcg acactagtcc tattatcaat
    33421 ctctcttttt tgtccattta cttttgcgac tgttccccaa taatcaaata caggaagcgt
    33481 tattttttgt cctttagatt catgtactgt atagactatt ttcgaatcca tcacttgata
    33541 aggcatagta tgccattcct tgccaattct tacttcatga ttctgcaaat gttctttgta
    33601 ttgtaatgct tccgtgggtg catagtcata aagtcctccg ggaaggagtg tcgtgtaacg
    33661 aataagattt tcttgattca ttaccaagtg atctctctga gtgacaactt tatgttcata
    33721 gtttgctttt gttgcagcag atacagccaa cagtaataaa acaattgccg ttatattaac
    33781 tacttttctt tgcttagctg atgtgctctt catgaaaacg aacgataaaa tcaacgagcc
    33841 aaacagtact tgaaagccta agattcgcca aggaaattga atcatttgaa tgggtgtatt
    33901 ttgtaataaa gaccatggaa aaaatttggt ggataagagc caagagacta ccgcactaag
    33961 gtaaatcact ttttctttgc gattaaatcc tttaaaaaag aagagtggac agatcaaaga
    34021 aataatacca atgattccta ccgtaaaggt tgtcaggtca ttattcatcg caccaatcaa
    34081 actatccgag acatttaatg cttggtgttg taaggtcgtt ttatctggct cattaatcga
    34141 ttgaaccatg atttgtcgga acatcggata ccaaaagtat gctgttaaaa gaatcgtcat
    34201 tcctactgcc tttgacaact ccacaatcaa ccggatgctt tctttttttc ttgtttcact
    34261 tactacaaag ccgcctaaga ctagtaagcc aacggctatt acactcataa aagtggaaag
    34321 aacatgtgta taaatgagta agctcatact gactgctaat ggaattgcac atggcttttt
    34381 ctcataaatc agtgcgtaag cataatacat aactatcggt ataaccgtaa gtgcaatcgc
    34441 ttcagcaata gcagaacgat gataaatatc aatcgtacgg tacccataaa atgtatataa
    34501 acagctaaat ataaaagccg catcgattct ttttaaaaat tttagtccat aatgaaacat
    34561 cagcatgata gtacaaacat tcaatagcca aacatataag atataactaa cgattaaatt
    34621 attacttatc caataaaaaa tgactgccgg aaaaaaggtc aagtagggat aaaaataatt
    34681 cactccgctc ccataatgat taaacgtcgt aaaattgatt ggaccagaaa aaattgaaga
    34741 taaccctttg actctagcaa aatggaaggc aatatccccc gatgtagaaa tagtatgaac
    34801 atttctaaaa taattgattg aataaagtcc agcaataatt gctaggagaa tggacaatat
    34861 tatttttttc tttacttgca ttacttaatt atatactcct ttcatggatt gctttatcta
    34921 gtataactta aattttaaat aaatcgttat ttatttttac tctcacttaa aaaagcacta
    34981 aaattataag agagggaggt aatggtctga acaccaagaa ttgttccaac atcgaattgc
    35041 ttaactaatg agttcaaagc ttaattatgt ggctcttata tttaccgagc gtggattgcg
    35101 atctctttag cgaaacaaac atctttcata aaaaaaacag ccatatccgc tttcttggat
    35161 atgactattt actactactt tactatcttt cattcttctt gtctcactta tgataaggcg
    35221 ctgggtatca tgagtgaatg atattgctga atacaaatag tccgaccaca ttaagttgat
    35281 cggacttcat aagcatttta ttgactaata cttttttgct taagaattga ttctaacatc
    35341 ttttgctaaa gttaagcatc ctatagttcc tgcattatct gctaacttag gtgtgacaat
    35401 gtattcttcg atatttggcg tatcgacata gccgttaatt agttctaaaa aacgtctttg
    35461 tactttcttt ttcagatgtt cttgttgcat gacaccacca ccaaaaatta taatatctgg
    35521 tgaaagcatc agggtcgtat tacaggcaca ttgtgcaata taatccgcct cgatttccca
    35581 gaacggatct tctatagaaa gatcttgtcc cttggttccc gtacgcatct cgatagcggg
    35641 tccagatgcc aacccttcga gacaatcatg atgaaaagga caagtaccag agaaagtatc
    35701 tcctgaatgt ctcttaacta acgtatgccc catttctgga tggctaaacc cttcaacaaa
    35761 aatcccatct tgtatagctc ctccaccaat tccagttcca acagtgtaat aaacaacact
    35821 ggataaacct tttccatgac ctgaaacata ctccccgtaa caagcagcat tcacatcggt
    35881 tgtccaggca attggaattt cgaaatgctt attcaacgtt ccaacaaaat caaaattttt
    35941 ccaggcagtt tttggagtag aggtgatatg tccataggtc tttgattcac gatggatatc
    36001 aatcggtcca aatgacccta ctccaatgct ttctaattgt tctttatagt gattaaagaa
    36061 atcaattacc aaactcattg tttcattcgg tgtagttgta ggaaaactca ctctttctaa
    36121 aacctttaaa tcatcattgc caatggcaca aacaaattta gtcccacctg cttctattga
    36181 gccatacatt tcttactcca ccgtcctttt atctaggaat tcgttcttcc ctgtctaata
    36241 gtttttcgaa aaactcatgt ggttcctttt ggtaccaata ggcaacagaa gaaatatcgt
    36301 cttgacgctc ataaagcttg atgtcatcat ttcctagggt ttggaaagta acacgtaaat
    36361 tttctttgaa actaatgggg tcgggtaaat gccagcggta caacccatgc atcggtaaag
    36421 catcatcgcc aaaaccatga actggatttg gattaggttt tccagcacta aaataatccc
    36481 gggtgtgatc tcttttagat tgaaaaggat agcccataaa tagcgtatta aaattttgag
    36541 catatgccct ttctccaaag ttctttttat ggaaagccca agcgccgcca aaataatctt
    36601 ctgctcctgt agatgttatt gtagggaaat cttcatctcc atctatataa aacttaaatt
    36661 ctccttcccc ccaccagtat ctttccaatg cgcacaaagc aaagtaggtt cctacataat
    36721 acccagtgcc tttgattcca tcaataaggg tgtaatcttt tccttttgtc gtgatgggtt
    36781 cacggttcca tttagcatga aaatacatcg catcatccgg tacttcagtc aatgcataat
    36841 taaatgtata aaaaatgtgc ttaataaact caggatgttc attcgttaaa gtaatcttag
    36901 ctttttttcg aaatggcatc tcaaaatagc aattcatccc tgatgttgga ttcactacga
    36961 ttggtaagga attcacttcg catcttgtcc caaacccatt acaaaaaaaa tctcctaatg
    37021 gactttctac agaaggagtg gattcatcat cccaataaat acgcaaaatt aaatcacgta
    37081 agacgaaact cccagcgatt gttttgtctg tcactgtcat ccaaaaatga cgtaaaattc
    37141 cagggccttc catttctgct aaagtaattg tctctccagc atttatcgga acagaaggtg
    37201 acccttttct cccaattcct agatgactcg ctgtcattgc cgctttccct ttttcaccat
    37261 ttttattttc tggtgaaata gttctacttt cctctccctt gtggagccat atattattta
    37321 aacaattcat tttattcgtc ctctatcctt tcttcacttt tttgattatt catatagatg
    37381 atttgttgtt gtgcctccgc aataattgct ccaatatcta aattatcatt tcctaactgc
    37441 aaagcgattg acattgccaa gggaagattc attcctgcaa ttacgtgcac tctgtcagaa
    37501 atataggtaa aaaacttttg atttacactt cctccagcca tgtcagttaa aacaattatt
    37561 tcgtctgtag tatccactaa ctctttaatt tgttcatcta tatcatcaat ttcttcgaca
    37621 tatgcacata agctactaat ttgattatgc atacctgtta aaaactctag tgtctcttta
    37681 aaaccctcag ctagtattga atggctagca atgatcaatc ttctcataat tcaaatcctt
    37741 ttcctttacg ctaatattcc aaatgcagcc ataaccatcg caaaaacaat aacgagtaga
    37801 atcaaaatgg tcatactgat ttttttctta ctgagtagat aatatgctgc agcagtaata
    37861 attactggaa ttaatgttgg taaaattttg tccaacattg gttggatttt catactaact
    37921 tcaccaaaag tgaatttaag tggcgttgaa acactgataa ctgaagcaat taatgatcca
    37981 actactgtta gccccaatac tgaagcagct tcagttaaat aattaatctt ttcaccgtat
    38041 tcagtaacaa tcttcattcc ctgcttataa ccaaattcaa agcctctcat tcggaaaaag
    38101 aagattacca tgattaaaat gaaccataaa aagattccta caggattatt ttctaaagcc
    38161 atataagccg caattgatcc catgatggtt gggatcatcg tcatcaaaag agagtcccca
    38221 ataccagcaa ttggacccat cgtaccaact ttaaagtcat taatcgcatc ttttgcttct
    38281 aatccttgct tttcctccat tgcaacacaa gcacctaaaa taatggctgc cagccaaggc
    38341 tgtgtattgt aatactgaaa gtgattattt aaagcttcga tgtattcatc atcatctttg
    38401 tataattttc ttaaaatagg tgacaatgcg taagtcacag atgcaccttg ctgtgtttga
    38461 taattaaagg tacaaactga catcaaccaa cgatagttcg ctttcctaag atcctttttc
    38521 gttacttgat atttttcgct cattttattc atcctcccca ataaacccaa catcagaagc
    38581 tcccgcagaa gcagtgattt gtgcatcttt ttcagctcta tgatacacat taaatgctaa
    38641 agcgaatcct atgatcgccg ctccaataat aggtaccttc aaaaaagcgg ctaagaaaaa
    38701 tccaacaagt aaataactaa tgtatcgacc tgtaggcata aagcgtaaca acatcgcaat
    38761 accaacagca ggcaacattt ttccggctaa tgttagccca tccataaacc aattaggtaa
    38821 aacatccaaa acgtaattaa cagcagactg tcctaaagta acggcaataa atactggaat
    38881 tgctgcagat aaaccaaaga aaattggccc caaccacaaa acactattca ttttcttaaa
    38941 ttctcgttta ttcgcatatt cctgtgattt gcgaacaaca aaaccattta agattttgac
    39001 aattacatct agttgcaccc ctaacatacc tacaggtagt cctattgcta atccggcttc
    39061 tactccaagc tggctaccaa atgccgttgc aataattgcg cacgttccat agtccggtac
    39121 agatgagcca ccaaaaccgg caactcctaa tgacatcaat tgaactgtac cgccaactat
    39181 caaacctgtt tttatatcac ccatcaaaat tcctgtgaat aatccccaaa aaactgcgta
    39241 atttacaaag atcatcggaa tcccataata atcaacatgt ttaataaatg ctaatatagt
    39301 cagcataata atttgaaaaa tagtaaaatg cattatcctt actcctttat cctaattttg
    39361 attgaatttc ctgtgcctta tccgccggaa caaattgtgt aacaatttct acaccagaat
    39421 ccaacaattt tttatacgtg ctgatatttt catctgatgc ataggctcta gaagatagct
    39481 gtaatgcatt atctttaaca acagtaccgc caacaattag tcggtcaatt ctaataccgt
    39541 tatctactaa atgaaggatt gtttccggct ctttcacgat gacaaatact ttttcctgat
    39601 cgtatttccc ctttttaaaa ttcgcaatcg ctgtttcttc agtgataatt gatacagcca
    39661 ttccagcagg tctagctaaa cgcatacttg atttttggat gtcgttattt gcgacagaat
    39721 catcgatcac catcactctg tttgctttag acattggtgc ccattgcgtg acaataatcc
    39781 catgcaataa acggttatca actctcgaca taacaatact cataaatact tcctccttta
    39841 tctttcattt tcttacaagc aattaccatg ccaaaacaaa aagaacttga taaatcaagc
    39901 tctttttaca taatcataaa cgtatttaac ctcatgaatc gggatgtcga cactataata
    39961 atgttcaacg acactgaaag attgcttaaa atgtgtctga aatttttgaa attcctcact
    40021 cgtttcattg aaataaattt catcttccaa agtattttgt tttactaatc gttcaattaa
    40081 gcaactaatg tgaacatata atccgaaaca cgtattatta tcaaatgaaa ttcctagatc
    40141 attttgtaag atgtatatag catctgaaac ccgttctaat aatttagtcg gatttaatat
    40201 ggtcaattgc tccattaaat tcgttagact aaaattcttc agaatattat tgttcaaaac
    40261 tttcagttca ttatcattaa agtgtctatt caattgattg gagaatttac ttatattcat
    40321 tcctaaaatc atatcttcaa ttgaaaagaa ttctacatct tctagatgtg gatttagtgt
    40381 tccaacaata aaaagaatat tgttctcttt acgaagctcc gataaatagt tttcattcac
    40441 taaagagtaa tagtcacacg tttctatgac aagatcagta tcccttggaa agctatcttc
    40501 aagtatcctt tttaatttaa acgaagttcc taatccgctt gcacaagaac agacaatcat
    40561 atccttctta atatttgatg attcataaat ataatccaca ttttgatttt cttttacttg
    40621 ttcaagaatc tgtttaagcg gtaaatctaa taatatctga tttgcaacat caatagccat
    40681 tcttgttgaa acattgttta gtagtccgaa ttttttttga gcgtctagtt ccaaatttag
    40741 ataaattttc tccagtgaac ccatatcaac aagtaaaata atttcttcat atccggtaca
    40801 ctcttgtaag tatctattaa ttttgtctgc aatctcacta cttgaagtca ttagtggcat
    40861 atcaatggcg tcgtatatat atctctcaac gatcctatta gcagtacttg ctatacaggt
    40921 tgccgttaga tctccatgag ccaaaatcag tgctaaacgt ttttgctgaa attctttact
    40981 acacattaac ttaaataaaa taaccaaaac atttttttga atttttgtta aataaatatc
    41041 ccctatttga ataaaacgat tgactaattg aacttctcga ctacaccaac tattaatatc
    41101 attgatgaag gaatataatt tatcgtccga tgttaattgg atttgataaa tccaagaatt
    41161 caaaaagata gacgttattt gaagataata atagtcaaat tctatttgaa aatctctctc
    41221 tatttcctta acatactgtc taaatcgaat ctcttgatag gtgggatatg ttaaagctga
    41281 attattttgg atatcaacat tcttttgtct aaaatatcta tcatatttct caaaaagctg
    41341 ctgcttatca gtgtctttct tccacgtttg ataaagatac tctataagtt cgttgatatt
    41401 aaaaacttcg tctacttttt ccaaatcatc catttgaata tattttaatt cattctgtct
    41461 tttcataacc ttcatgccgt tgaaattcac ccattgtggt aaatgataca tctgaatata
    41521 aagttcttcc aaatcatcta agaaataaaa ggcattggca caggtcaatt gaatgatatt
    41581 tttcaaattg ccaacatttt cactaaagcg atagtttaat aaaaaatcta ataattgttg
    41641 agatatcagt attttctttg ctagtctttc ttcttctgat ttaaaaaata tcttgattaa
    41701 ctgttttctt tcataaagag aacgactgtc taatgttgga agtgttagct ttacaggtat
    41761 tcttctcaac aaagttgata atagtttatc ctcaggtggt tctgatgttg caaatataat
    41821 ccagcaactt gatgtgtacc agttttcatt atcacccatc cgatgaaatt tcctcgtatc
    41881 cataaactga aaaagtttct cctgacattc attgctcaat gcatgaattt catctaaaaa
    41941 taagactcca ttattagcta attctgctaa accctttctt ccatcttcgg ctcctgtata
    42001 tgcacctttt acatgcccaa aaaaattgga caagaaaagt tctggattat tggcatattc
    42061 actacaatta actgaaatga aagatgcctt ctcttctata taattattgg ccaacaaatc
    42121 cttatacaca taatttgcta aatagctttt tccagttcca gtctcgccat gaagtaaaat
    42181 gggtaagcca tttggcggat agtagattgc tgctttaatt tgagcaatta catttcgcag
    42241 acttccttga cttccgataa ccctttctat tccaacccta aaagagctat cataccattt
    42301 ttccgcttcc tctgaagagc taaaaatttg ttgatttgga actttctccg gtaaagaaaa
    42361 gaagattact ggacgagtat tgatttttcc aaattctcca tcttttacga attcattcaa
    42421 atattgagag acaatattac gactaacatt taatttttca gatattttct gtgctgtatt
    42481 gttcccccat ttatttttaa tctcagagtt ctctatgaca taattgacaa tgcgttcttt
    42541 taattcttcc atcacagcac ctcctcgaca ctattcgaat tttgccgaca gtatttttcc
    42601 ataaatatga cttgctaaaa aggctttgtt tagatcattc aattggaacg ttgcttgttt
    42661 tgcttgatcc gctaagacgt tgaaaagata ctctggcgaa atcgcatacc ccaaaatatc
    42721 aacgattgtt gcaatcagat cttcttttga ttcttcatct gaaagtaatt cacgatacaa
    42781 catcgtttgt ttgcttactg tgtcatattc ctctaaggat tcatctgcta aaagaaccac
    42841 ttgttccaac aaacggtcgg ataaatattt atagaaaatc agccccaata aataattttt
    42901 atattctgac gcatccattt tactacggag attatctgcc gcactaaata acttctgatt
    42961 taattctgca cccaaaaaga tacactccta tctcttattt aaagttgcta tataccctct
    43021 tattttagca tactcagttt tagaaaaagc aaaaaaataa agaaacttat tcttgataac
    43081 aagctacgtg acgtatatcc ctaacacaaa aatagccata tcctttggtt tggatacggc
    43141 tatttgatat tactcattca attatcaaat cacagtaggt gtgaatctca tcgggatcgg
    43201 caatatctac ttctgattag gatcaaaggt gattttctca ataaaggtgt gatacaaagc
    43261 tttaacttgc ttcttctcac tctggataag aaagcaatcc aaactagtca atatctgttg
    43321 gacatctttg acttgaatcg gttccccttg ttgttgaaag atccctaaga tttcattctc
    43381 tcgaatttgt aactgtcttc gtttttcagt caattcattt aaacgatctt ttaacatcgg
    43441 aaacaattcg ggactatctt ccaaagcagc ttcctgtttt tgctctaata gttagatttt
    43501 gcgtaccatt ttcttctttt attttccttc gattgctgat tttaatatag tctaaaggaa
    43561 atttatattt attgtattct ttataacttc aagagaactt cgtttgagta ttactgtatt
    43621 tttttaattc cataagaaaa ttagttatta cctgccacct aatcagcaaa tctgaacctg
    43681 agtcaatata attaatatta ttttccatct ccaacattgt aagtactgtt ggtgttaata
    43741 tagggacttt gtacaattgt atttttttga ttttatcatc tgcacaaagg agatttttta
    43801 aatctaatcc ttcttttatt tcaaaagttg aattttttaa atctataaga gtaaaaccaa
    43861 ttccttcata ctgaatttct gaaaatcgaa tttttctccc agttgataga tcaaggggca
    43921 gaaaaccttt tattacattg tgagtgtcac catcatttac aatgtcatta ggaattttga
    43981 ttttagaatt ctgtggagca cctattggaa gataataatt cattataatt ttgtagtctt
    44041 catgaggaaa taaagtactt ttaggattgc taagatattc tcgtaccgaa tctaagaatg
    44101 gcttatccat tgaatcttca tccccattta aactaaaaaa cattcctaca attgcttttg
    44161 caactctaag tgaattcatt ttctttattg aatgtgttaa atcagactta ccattcttta
    44221 aacttgtatt gttataaagg aaatttttat tgtcttctgc aaatctaata tattcctcaa
    44281 catactcact accaaaaaaa ctattacatt tactacataa cgtattggaa tggcaacagt
    44341 ttttttgaca aattttataa ggtgcagaac ttctttccgt atgctattcc gattgtcctt
    44401 gacaatgagc ctcctcggat gtgacgatct tcggcaggag ctaacagtta aagttagact
    44461 gcctcgctag cgttagcaca tccgagctca ttatcaagga ttcgctgcgc caat
//
LOCUS       DAFLVO010000017        42754 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.017, whole genome shotgun sequence.
ACCESSION   DAFLVO010000017 DAFLVO010000000
VERSION     DAFLVO010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42754
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.017"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            10..255
                     /locus_tag="L1U99_000963"
     CDS             10..255
                     /locus_tag="L1U99_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBN1211520.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            348..794
                     /locus_tag="L1U99_000964"
     CDS             348..794
                     /locus_tag="L1U99_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1211521.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(853..1314)
                     /gene="mscL"
                     /locus_tag="L1U99_000965"
     CDS             complement(853..1314)
                     /gene="mscL"
                     /locus_tag="L1U99_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HBN1211522.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            1566..2834
                     /locus_tag="L1U99_000966"
     CDS             1566..2834
                     /locus_tag="L1U99_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBN1211523.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            2827..4113
                     /locus_tag="L1U99_000967"
     CDS             2827..4113
                     /locus_tag="L1U99_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBN1211524.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            4852..5775
                     /locus_tag="L1U99_000968"
     CDS             4852..5775
                     /locus_tag="L1U99_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1211525.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            5984..6562
                     /gene="pgsA"
                     /locus_tag="L1U99_000969"
     CDS             5984..6562
                     /gene="pgsA"
                     /locus_tag="L1U99_000969"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBN1211526.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            6802..8043
                     /locus_tag="L1U99_000970"
     CDS             6802..8043
                     /locus_tag="L1U99_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBN1211527.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            8152..9201
                     /gene="recA"
                     /locus_tag="L1U99_000971"
     CDS             8152..9201
                     /gene="recA"
                     /locus_tag="L1U99_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBN1211528.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            9612..11168
                     /gene="rny"
                     /locus_tag="L1U99_000972"
     CDS             9612..11168
                     /gene="rny"
                     /locus_tag="L1U99_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBN1211529.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(11247..12053)
                     /gene="proC"
                     /locus_tag="L1U99_000973"
     CDS             complement(11247..12053)
                     /gene="proC"
                     /locus_tag="L1U99_000973"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBN1211530.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            12194..14767
                     /gene="mprF"
                     /locus_tag="L1U99_000974"
     CDS             12194..14767
                     /gene="mprF"
                     /locus_tag="L1U99_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBN1211531.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            14909..15772
                     /locus_tag="L1U99_000975"
     CDS             14909..15772
                     /locus_tag="L1U99_000975"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBN1211532.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            16017..16955
                     /locus_tag="L1U99_000976"
     CDS             16017..16955
                     /locus_tag="L1U99_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBN1211533.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            16978..17658
                     /locus_tag="L1U99_000977"
     CDS             16978..17658
                     /locus_tag="L1U99_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBN1211534.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            17631..18455
                     /locus_tag="L1U99_000978"
     CDS             17631..18455
                     /locus_tag="L1U99_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBN1211535.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            18622..19440
                     /gene="purR"
                     /locus_tag="L1U99_000979"
     CDS             18622..19440
                     /gene="purR"
                     /locus_tag="L1U99_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBN1211536.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            19943..21316
                     /gene="glmU"
                     /locus_tag="L1U99_000980"
     CDS             19943..21316
                     /gene="glmU"
                     /locus_tag="L1U99_000980"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBN1211537.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            21410..22381
                     /locus_tag="L1U99_000981"
     CDS             21410..22381
                     /locus_tag="L1U99_000981"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBN1211538.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     regulatory      22387..22489
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            22555..23124
                     /gene="thiT"
                     /locus_tag="L1U99_000982"
     CDS             22555..23124
                     /gene="thiT"
                     /locus_tag="L1U99_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HBN1211539.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     gene            complement(23205..23978)
                     /locus_tag="L1U99_000983"
     CDS             complement(23205..23978)
                     /locus_tag="L1U99_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211540.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            24245..25945
                     /locus_tag="L1U99_000984"
     CDS             24245..25945
                     /locus_tag="L1U99_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBN1211541.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            25915..26133
                     /locus_tag="L1U99_000985"
     CDS             25915..26133
                     /locus_tag="L1U99_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HBN1211542.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            26153..27043
                     /locus_tag="L1U99_000986"
     CDS             26153..27043
                     /locus_tag="L1U99_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBN1211543.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            27061..27345
                     /locus_tag="L1U99_000987"
     CDS             27061..27345
                     /locus_tag="L1U99_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211544.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            27832..28446
                     /gene="gmk"
                     /locus_tag="L1U99_000988"
     CDS             27832..28446
                     /gene="gmk"
                     /locus_tag="L1U99_000988"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBN1211545.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            28451..28756
                     /locus_tag="L1U99_000989"
     CDS             28451..28756
                     /locus_tag="L1U99_000989"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBN1211546.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            29009..31417
                     /gene="priA"
                     /locus_tag="L1U99_000990"
     CDS             29009..31417
                     /gene="priA"
                     /locus_tag="L1U99_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBN1211547.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            31432..31923
                     /gene="def"
                     /locus_tag="L1U99_000991"
     CDS             31432..31923
                     /gene="def"
                     /locus_tag="L1U99_000991"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBN1211548.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            31916..32854
                     /locus_tag="L1U99_000992"
     CDS             31916..32854
                     /locus_tag="L1U99_000992"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBN1211549.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            32854..34212
                     /gene="rsmB"
                     /locus_tag="L1U99_000993"
     CDS             32854..34212
                     /gene="rsmB"
                     /locus_tag="L1U99_000993"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBN1211550.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            34225..34965
                     /locus_tag="L1U99_000994"
     CDS             34225..34965
                     /locus_tag="L1U99_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBN1211551.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            34962..37031
                     /gene="pknB"
                     /locus_tag="L1U99_000995"
     CDS             34962..37031
                     /gene="pknB"
                     /locus_tag="L1U99_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBN1211552.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            37196..38095
                     /gene="rsgA"
                     /locus_tag="L1U99_000996"
     CDS             37196..38095
                     /gene="rsgA"
                     /locus_tag="L1U99_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBN1211553.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            38108..38758
                     /locus_tag="L1U99_000997"
     CDS             38108..38758
                     /locus_tag="L1U99_000997"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBN1211554.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            38759..39397
                     /locus_tag="L1U99_000998"
     CDS             38759..39397
                     /locus_tag="L1U99_000998"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBN1211555.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            39552..40406
                     /gene="mreC"
                     /locus_tag="L1U99_000999"
     CDS             39552..40406
                     /gene="mreC"
                     /locus_tag="L1U99_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBN1211556.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            40410..40919
                     /gene="mreD"
                     /locus_tag="L1U99_001000"
     CDS             40410..40919
                     /gene="mreD"
                     /locus_tag="L1U99_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBN1211557.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            41174..42748
                     /locus_tag="L1U99_001001"
     CDS             41174..42748
                     /locus_tag="L1U99_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBN1211558.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
BASE COUNT        14097 a         7635 c         9248 g        11774 t
ORIGIN      
        1 gtgaactgta tgccaacaac tttagcttca atcaagaaag atttagaagg tcgtatcggc
       61 agcccaatca tgttggttgc tcagacagga agaaagcgtc aaacagaacg ccgcggcgtt
      121 ttaacagaaa cctatccttc agtattcgtt gttgatttgg atcctgaaga aaattctttt
      181 gaacgagtat cttacagcta ttcagatgta cttactcgga cagttgagat cgaattttta
      241 actgaagcag tttaaaaagc aaacgagcct gagattcgta aggttcgttt gcttttttgt
      301 gtgcgaatcg gtatgctaag aataaaaaag cagggggcgt ttgcttagtg gaatatcagg
      361 taaagaaatt tgaagaattg tcaacagcag agttttacgc gatcgtcaaa gaacgaatcg
      421 cagtttttgt tgtggaacaa cagtgtcctt atcaagaagt tgatgacatt gatggagaag
      481 cttggcatac gttttttcaa gatactgatg ggaagatcct tgcctacacg cgagtatatg
      541 aagaagcgga gagtatccat tttggacgtg tccttgttca tcaggacaac cgtaaagatg
      601 gtttaggaag aaagattgtt caagaaacga ttaacatgat ccagaaaaat tttccagaaa
      661 aaccaatcgt gatcggcgca caagaatacc tacaagcttt ttatgagtcg tttggattca
      721 aggcaatctc agatgtgtat ttggaagatg atattccaca tatcgacatg aaaaaggaac
      781 aagtagcaag ttaagaatct aaaaaaagaa agccgacact gaaaatcggc tttctttttt
      841 ttagattctt tattatttag aagtatcgga aagatttgtt tgctctactg gatgtgtatt
      901 gtcttctgcc acttgtttgg caagaagatc gcgtatgtca ctaagataat cttctgcagt
      961 aggagtttct tccacttcca cttgctcttc tttggagcgt aaattcttcg cacggtttgc
     1021 cgctttgaca actaagaata agacaaaacc agtgatcaga aatgtaatga tagcactaat
     1081 aacgttacca aacgcaaatg tgacgccttt tgtcggcgac cagtcaagaa ttgaaagtgc
     1141 tccttctaaa tcagaagtac ctgtgatcat tgcgacaaac caacctatta gtggtgtgat
     1201 caagccttgc accacttggt ttacgatgct tgtaaacgca ctaccaataa caacgccgac
     1261 agcaagatcc aagacatctc cacgcatgat gaactctttg aattctttga tcatgaatga
     1321 ccctcccttc ttttatttgt ctttagtata tcgaaaaata aaaaataaaa aaacaatata
     1381 cgcttttagc cgtctgtttc ttttgataaa aaacatctat gctatactat aaagtgtaac
     1441 atcatttaga aaaaacggcg aattgcctga acttataaat ttcaagcaga ggaataagta
     1501 aaaaaggcag gttgacccat taaaagagta agcgggcaat caactgtgaa aaggagcata
     1561 taaatatggt gtatcaattg gcagaaggcg tgaatcttca tgtcttacca acaaaacaat
     1621 acaaaacgat ccggattttt atccgtttta ctgcgcgtct gcaacaagaa gtcatcacga
     1681 aacgttcact tctcagcagc atgttggaaa caaatagttt gaattattcg gatcagacaa
     1741 agttaagtgc gcaacttgca gagctttatg gcgcaagctt tggattatca gttagaaaaa
     1801 aaggaaattt acattggcta aacgcaggga tcagttttgt gaatggtgaa tatgtcaatg
     1861 atccaaacct tttttctcaa gcggtagatt ttttaaaaga ggttttattt tatccaaata
     1921 ttaaaaatca tcagtttgat cagttgacgt ttgacttgga aaagaacaat ctgcgtctat
     1981 atttggaaag tttgaaggaa gataaacaaa cttttgcttc ctatgccttg caagaacttt
     2041 attttgaaaa cagcccggaa caaaagatcc cagggttggg cgtagtcgaa gatttggaca
     2101 agatcactgc tagttcgcta gcgtcctact atcaagaaat gatggcaaat gatcaaatcg
     2161 acatttttgt tgtcggcgat gttgatccgg acaaagcagc tgaagcagtt gggcaattac
     2221 catttgagtc gcgggaaaca gtttatccag atctgtttta tacccaacct caagtgaata
     2281 tcgtgaagga acgacaagta cgtgagccaa tcgttcaagc aaagctgaac ctagcttatc
     2341 agacaaatgt gtattacgat gaaccagaac gttttgcgct aatggtcttt aacggtttat
     2401 ttggcggttt tcctcactct aaacttttca tgaatgtcag agagaaagaa agtctagctt
     2461 attatgcctc tagtagcgtg gatacgttcc gaggattcat gagtgtccaa accggtatcg
     2521 atgaaaagaa ccgaaatcaa gtacttcatc tgattcacga gcaattagaa agtttgcgaa
     2581 atggtgaaat aacagagttg gaactgtctc agacaaaagc aatgctgaga aaccaatatc
     2641 tgctttctct agactctccg caagcggcaa tcgaagcttc ttttttggac agctggctgc
     2701 cggaaacaaa attatctgat gaagaatggt tgaaacgtat ggagagcgta acgatcaaag
     2761 agatacaaca agtagctgag caaatcgaat tgcaggcaat cttcttttta gcaggaggaa
     2821 atgcaaatga ataaaacaga atatgagcaa atcaatgaaa cactttatca tgaagtactg
     2881 ccaaacggtt tgaccgtgta tttgttgcct aaaaatgact atcacaagac atatggtttg
     2941 ttcagtacga attatggttc gatcgataac gaatttattc cctatggtga aaaagaaaag
     3001 gtgaaagttc cagatggaat tgcccatttt ttagaacata agttgtttga aaaagaagat
     3061 ggtgatgtct ttcaattatt tgggaaacaa ggagcttccg ccaatgcttt cacaagtttt
     3121 acgaaaacca gctatctgtt ttctacgacg gatcaggtag aaaagaatct gacgactctg
     3181 atcgattttg tacaagcacc ttacttcaca gaagaaactg taaacaagga aaaaggaatc
     3241 atcggtcagg aaatccaaat gtatgaagac gaccctaact ggcggatgtt ttttggcata
     3301 ctaaataact tgtatcctac acacccattg catatcgata ttgcgggcac ggttgaaagt
     3361 atcgacaaaa tcacagctca agacttgtat acgtgctatc ggacgtttta tcagccaagc
     3421 aatatggttt tatttgtagt tggtaagatg gagcctgaga aattgatgaa acttattcgg
     3481 gaaaaccaag aagcaaaaaa tttccctcca aagcaagaaa ttgtacgtta tttccctgaa
     3541 aacacaaaag aaatcatcaa acaaagtgca ttggaagcag ccattacacg agataaattt
     3601 gtacttggta ttaaaggatt agacacattg ccgcaagaag gaacagaact gttacgctat
     3661 aaaacagcaa tcaatctgtt gttccaaatg attttaggca atacttctcg aaactatcta
     3721 gcgatgtaca atcaaggaat tatcgatgac agctttggtt ttgaattcag cttggatcgt
     3781 gaatttcact ttgcggactt cagcggagat acggacgaac cagagaaagc agcagaaaaa
     3841 gtcaaagaaa tcattcttgg attcgctgat gatccggaag tgtcagaaac aaatctcgat
     3901 ttgctgaaga agaaaatgct tggacaatat ttccaatcat taaattcgat cgaatatatt
     3961 gccaatcaat ttacgcaaag tttatttggc gatcgaactt tatttgatct tcctgaaatc
     4021 atcgattcga tccaaatgaa agacgtactg gcagctgggg aagcatttat aagtgaagag
     4081 gccttcagcg agttttacat gagaccaaaa taaaccagta ttttatgagg aaaagtctta
     4141 aatttcgttt tagacttgta gtaggaacct cctccaaaat cagcttttat ggtattctta
     4201 gttgtgttgg aaaaattagt gagaaaataa aacaaatcat gctctctttt aatcaactta
     4261 tattaaaata aaatcaaacg aagtaatcaa agaggttgtg acagaagtgg tcagcttcaa
     4321 gaaataagaa ggaatttacg aaaattgctt ctcaaatttt tgtgatattt cggcttattg
     4381 ccgaagaagc tacttctgga acaccgtgta ccaagaggtt gtgaaaaagc tgccctgcat
     4441 caagtaataa gaacagccaa gtaaaaacag cttcttaatg tttttaactt ggttggactt
     4501 attaccgcag atgcaagctt ttgaacaccg tttaaggaag aggttgtgaa atcagcgttt
     4561 tgacctgagt attagagaaa catacggaaa aatatctcct tatattttgc cggtttttga
     4621 gctaataccg aggaacagct gattgaacac cgtttaagaa agaggtcgtg agcctgccgt
     4681 ttaactccga gtcacaagga acaagttcaa aaaacagctt cttatattta ttggatattg
     4741 tgacttgtga ccgaggagtt ggcaggagaa caatgtttat tcggaaaaaa ggagctgtga
     4801 catgactttt gtcacagcac ccaaacataa cgtctttcgt tgcaacagca gatgcttcgg
     4861 agaatcaaac agactggaga agatgaacga gtggcttttg aaaccatcgg agaaaaatta
     4921 cggcaagcac gcctgaataa aaaaatatct ttagatgaat tacagcagat tacaaaaatt
     4981 caaaaacgtt atttggaagc aatcgacaat gatgattttg accaattgcc tggtaaattt
     5041 tacgtgcggg catttattcg gcaatacgct gaagctgtag gagaagatgg agaccattta
     5101 gtcgatgttt ttgatgggaa aagcaaattg acaggatcgg tccctgaacg tccgcagcct
     5161 gaaacagtaa gtacttctag aaaagcaatg catcaggaag aatcgcatcc aagtcgcttt
     5221 tggacaagtc ttcctgtcat tttattagga ttggttgctt tggcgattgt cgttgtcgtg
     5281 ggctatatga cttggcaaga tcgtcaagct gatccaataa tcggagacac agcttcttcg
     5341 cttaaagtag aaggatcagt cgaggagtcc tcttcctcag agcaaagcac gcagaccaaa
     5401 gagtcttcta cagtagaatc aacaacaaaa tcaagtgaag aaaagaaaat ggcaatagct
     5461 acaggagaag attctggcag tgccatcgca gtaaatatca cagacgctac caagcctgta
     5521 acccttgaat ttactgctgt caatcgtgta tggttaggtg tgctagtaga caatgcctat
     5581 gtttatcaag ggacactggc agcaaatgaa acacagagta ccgtgttacc ggaaacagca
     5641 acaaatgcga ccatcacgat tggtgcagca agcaatgcaa cgatcaaagc gaatggagaa
     5701 tccgtaccag ttaatccagg ggaaaacaat cagagtccaa aaaatgtgaa ccttactctt
     5761 caatacgcag aatgatcgta taaattagtt tacgcatctg tttacttgta ggtataaaaa
     5821 agaaggatcg tgacaaatct gtgtcgcggt ccttcttcgt taattcaaaa agatcaattt
     5881 caataaaaat actcctttga ataaattcat ttggaaaagt aaataatatc ggtggaaact
     5941 tcgctgatag tcacgtagaa tagggaagaa aggagtcgat agtgtgaatt taccaaataa
     6001 attaactgta cttagaattt gtatgatccc gattttcatt ttggttgtag gtttaccttt
     6061 agattgggga caatttaacg taggagacac cacactggct gtcacacagc tagtaggtgc
     6121 agttattttt gctttagcta gtatcacaga ctggttagat ggaaaaattg cccgtgcgcg
     6181 aggccttgtc actaattttg gcaagtttgc ggacccgttg gcagataaaa tgctagttat
     6241 gactgctttt atcatgttgg ttgaccaagg aaaggcccct ggttgggtag tagcgatcat
     6301 tgtctgtcgt gaattagccg tcacaggctt gcgtttacta cttgtcgaac atggagaagt
     6361 catggctgca gcttggccgg gaaaagtcaa gacggctaca caaatggttg ctattatctt
     6421 gctgtttatc aataatatcc cattcagcct gatcggtatt ccagtagatc aaatcatgct
     6481 ttatgcttgt ctgatcttta ctatctattc aggtgtggat tacttcatca aaaacagcgg
     6541 tgtgttcaaa ggatcaatgt aagtatcgtt tagtggagag gttgtgagcc tgccgtctaa
     6601 ctctgagtca caagggataa tttcaaaaaa cagcttttca tgttttatgt atattgtgac
     6661 ttatgaccga ggttttggca ggagaacact gtttatttgg aacaaggagc tgtgacaaga
     6721 tttttgtcac agctccttgc cctcttttta aataaaaaaa tataaaaata cagcgtatac
     6781 tatataaggg agcgggaagt aatgaaagca gaaataatag ctgtcggaac agaactttta
     6841 ctaggacaag tcgtgaatac gaatgccact ttcttgtcag aacagctagc tgatctaggt
     6901 atcgaagttt attatcaaac agttgtagga gataatcagc agcgtttaga agagttgatt
     6961 gctctagctg aaacaagaag tgaactcata ctcttatgtg gcggattagg accgacagaa
     7021 gatgacctga caaaagaagc aactgcggct cacctcggta agtctctcat acaaaatacg
     7081 gaaggataca aaaaattatt ggcatatttt gaaacaaccc atcgaaaaat gaccaaaaac
     7141 aatctgcaac agtcccagat tatcgaaggc ggggttcctc taccaaatcg tacagggctt
     7201 gctttaggga ctttttatca aacagataca catgcgtata tccttcttcc cggtccgcct
     7261 aatgagttga aaccaatgtt tgtggaacaa gtacgtcctt tactagagga acgttttcct
     7321 tctgaagaaa aactaatttc taaagttttg cgcttttatg ggattggtga atcgcgactg
     7381 gtcactgagc taaaagatct gattgagaca cagatcaatc caacgatcgc accatatgcc
     7441 aaaccaaatg aagtgacatt acgactgaca gtgaaaacaa atgatgttca ggcagggaat
     7501 caagctcttt tagcattaga agaaaaaatc caagaacgag taggggaata tttttatgga
     7561 tacggcgatg ataattcgct agcaaaagtc gtagtggaac tactgaaaga aaacaagcag
     7621 actgtaacag cagcggaaag tttgacagcc ggcgccttcc aagccgcatt aggcgacatt
     7681 gctggtgtat ctgaagtatt tccaggcgga ttcgttacct actcgctcca aacaaaagct
     7741 ggttttctgg agattgatcc ggagctatta gcagaatatg gaacagtcag caaagaatgt
     7801 gtggagcaga tggccattca agcacgtgag atagcaagaa cagattacag tgtagctttc
     7861 accggagtgg ctggaccgga cacgttagaa ggtcaatctg caggaacagt atggatcgct
     7921 atttcatcta aagacggcgt ggtttcggaa aaatatcact ttgccagaga tcgtgctgct
     7981 atcagatata atgcggttat gcaaggattt gatcttttga gaaaacagct tttaagaaaa
     8041 tgataaatgc gaatatttgt tcggtttttt cttgcttttt ttcactaaaa aagatatgat
     8101 aaggataatg aaatgttgct ctgatttgta aatataagga ggattatcgt attggcagat
     8161 gatcgtaaag cagccttaga tgctgcactg aaaaaaattg aaaagagcta tggtaaaggc
     8221 tctattatga aattgggcga aaaaatcgac caacaaatct ctacaattcc aagtggctct
     8281 cttgcgttag atgtcgcttt aggtgtcggc ggttaccccc gtggacgtat catcgaagta
     8341 tatggacctg aaagttcagg taaaacaaca gttgcactac acgctattgc agaagtacaa
     8401 aaaaatggcg gaacggccgc tttcattgat gctgagcatg cgttagatcc gcaatatgca
     8461 caaaaattag gtgtgaatat cgatgaacta cttctttcac agcctgacac aggagaacaa
     8521 ggtctagaga tcgctgatgc tttagtatca agtggggctg tagatatcgt agtagtcgat
     8581 tcagttgctg ctttagttcc acgagcagaa atcgacggcg aaatgggtga ctcacatgtc
     8641 gggttacaag cacgtttgat gtctcaagca ttgcgtaaac tctctggttc gatcaacaaa
     8701 acaaaaacaa tcgctatttt catcaaccaa atccgtgaaa aagtaggcgt gatgtttggg
     8761 aatccagaaa tcactcctgg aggacgcgca ttgaaattct acgcaacgat ccgtttggaa
     8821 gtacgtcgtg cagaacaatt gaaacaaggt acagatattg ttggtaaccg tacaaagatc
     8881 aaagtcgtaa aaaacaaagt agcacctcct ttcaaaatcg ctgaagtaga tgtcatgtat
     8941 ggtttaggga tctcacaaga aggagaactt ctagacatgg cagtagaaaa agacattgtt
     9001 gataaaagcg gtgcttggta ttcttataaa gaagatcgga ttggtcaagg acgggaaaac
     9061 gctaaaatct atatggctaa tcatcctgaa atgatggcag aagtttctgc tctagttaga
     9121 gcagcttatg gtattggtga agaagtcgct gtcccagaag atgaaaaagg acaagaagaa
     9181 ttgcctttag tagaagaata aaaattatga taaacaaaaa cggctggtct gaagagtagg
     9241 tactctcctt gacctgccgt ttttttattg aataaagaaa tcgtgagtta tttaattata
     9301 cgagtgggta cataaaataa aaatatctgt tcatctacaa agaataattt aatagaaaag
     9361 tttctcaatt taaaggttta cctatatgaa actagtgtca tttattttaa aaaccatcgt
     9421 ttaatgaata agtagaaagc cgtttctttg tttatttaaa gttgacacta cggggtacaa
     9481 acattagaat aaagttgtgc atgttttttg tacacatata tgcgaagatg catattgacg
     9541 agtttagaat aatttatcat agaagctgta tagatgataa aaatgaaaaa gatagtatgg
     9601 aggtggattt tatggtattc aacattctcc tcgctatcat cggtttaatt gtcggtcttg
     9661 gtttagggtt tatggtcgca aagtcacgtc acgagaaaga aatagctggt gcacaatcat
     9721 cagctgctgg aatcatcgat agtgcaaaaa aagaagcaga aactctaaaa aaagaagcat
     9781 tgttagaagc taaggaagaa aatcagaaat accgttctga agttgaaagt gagctgagag
     9841 aaagtaagtt agaattaaaa tctcaagaga atcgtttgat tcaacgcgaa caaacgctga
     9901 atcgtaaaga tgactcgtta gaaaaacgcg agaactcact tgaaagtaaa gaagaagcac
     9961 ttagttcaaa acagcaatta attgaagagc gagaaaaaga cgttgaaaaa atgattgaag
    10021 atcaacaaaa agaactagaa aaaattgctg gtttatcaaa agaggacgca cgagatgtca
    10081 tcatgaaatc gactgaagaa gagctgaatc atgagttaac tctaatggta aaagaatctg
    10141 aacagcgtgc caaagaagaa gcagatcgca aagcgaaaaa cttattatca ttagcgattc
    10201 aacgctgcgc agcagatcaa gtttcagaaa cgactgtttc agtcgttacc cttccgaatg
    10261 atgaaatgaa aggtcgtatc attggacgag aaggtcgtaa tattcgaacg cttgagacgc
    10321 tgactggtat cgatttaatc atcgatgata caccggaagc agttgttctt tccggattcg
    10381 atccaatccg aagagaaatc gcacggatga ccttggaaaa actgatacaa gatggacgaa
    10441 tccatccagc gcgtatcgaa gaaatggtcg agaaatctcg taaagaaatg gatgaacgta
    10501 ttcgcgaata cggggaagag gcagcgtttg aagtcggtgc tcatacactt catccagatc
    10561 taatcaagat catcggacgt ctgcgattca gaactagtta tggacaaaac gtcttgaagc
    10621 attcggtcga ggttgcaaaa ttagctggta tcttagcagc agagcttggc gaagatatcc
    10681 aattagcaaa acgtgccggg ttgctccatg atattgggaa agcacttgac catgagattg
    10741 aaggatctca cgttgagatc ggtgcggaat tagctgccaa gtacaaagaa aacccagtag
    10801 taatcaacgc gatcgcttct catcatggag atgtggaagc tacttctgtt atctctgtcc
    10861 ttgtagctgc agcagatgcg ctctcagcag caagacctgg tgcgcgaagt gaatcattag
    10921 aaaactacat ccgtcgttta agaagtctgg aaaatatttc gaacagcttc gccggtgtag
    10981 aatcaagtta cgcagttcaa gctggacgcg aagttcgggt aatggtcaag ccagaagaaa
    11041 tctcggattt agacgctgtt cgtttagtac gtgatattcg taaacgaatc gaagaagaac
    11101 tggattatcc tggacacatc aaagtaatcg ttattcggga aactcgtgca actgattatg
    11161 ctaaataata aaaaatacaa aagaagagcc gcggcaaaag ccacagctct tctttttttg
    11221 taaggcacga aaaaacattg ctatcattat tttttattca acatctcaag atctttctcg
    11281 atcgtcgtat tgattccttt gatgattgct gggatgaatc ctgcttcttc taaggcaact
    11341 acacctgcaa cagttgtacc gccaggagaa gaaacttggt ctacaagttc ccatggattt
    11401 ttatcacttg aaaggaattt ttgacaagaa cccataattg cttttgcagc aatctcagtg
    11461 gctgtctgtt tggacaaacc attcagtaca ccagtccgtc ccatcgcatc gatcagcatg
    11521 taaacgaatg cgggtgagct gccagcaagg ccaatgaatg tactgaaatc tgattctgct
    11581 aaaggataga cgctgccgat tgcttcaaaa atcatcgtag cttgctgaag ctgttcctcc
    11641 gtggcagctt catttttgca aatcgcagaa acgcctgctc ctacgctgac attgacattc
    11701 ggcatcacac gtacgatgga ggcctgagga tcttcaagcg ctgtttctaa atctattaat
    11761 gattttcctg aagcaataga aatgaataag actttctggc tatattctct tagttcttcc
    11821 aatacttttt caatgatttt tggtttcacg gctaaaagaa cgatatctga ttgtgatgca
    11881 acttcctgat tacttttgca tgcatggacg ccagtttcag cagcaaattt ttgtgcattt
    11941 tcaaaatgtc cactggaaac gaacacctct tctttcgaga ctgttccttt ttttaataaa
    12001 ccatcaataa tagcttgtgc catattccct gtgccgataa atcctacttt catgttatcc
    12061 tctcctttag cattaggata tctttctttt tctatcatcg caagcaaaga acaggtctaa
    12121 agtggaaaaa ttaaaataaa taagataaca ttggggtatg acacaaaagt atacaagtta
    12181 ggaatgggaa aatgtgaaaa ataaacgata cttgatgctg caatggataa aggaacatag
    12241 tctgatttta aaactgattt ttttcggctc cgtgttagtc tttgtggcaa atcaagtcgc
    12301 aaatattgct aatggcatga gttggcaaga tatttggcaa aggatgggac aacaaagccg
    12361 catgacgatc ctgctcatga ttctggctgg actgctgggt gtcactccga tgttgttgta
    12421 tgattgggtg acgatcagag tcttagaaaa acaaggaaaa ccaaaaatgg aaagaaaaga
    12481 gtttcttctt gctgcgtggg taacaaacac gatcaacaat ctcgccggtt ttggtggtgt
    12541 ggtaggagca agtctgcggg ctagttttta tggaaagcag acaaatagaa aaatggtttt
    12601 agccactgta tcaaaagtcg cactatttat gctgactggt ttgtctgtat ggtcgtttct
    12661 tacatttatt gatgtctttt ttattcagtc agaaagtatt tttcgaagct attggatctg
    12721 gcttttcggc ggtagttttt tagcaccagt cattttcttt tttgcttatc taaagagaaa
    12781 gacattgttc ttcgagtttt atccaaaagg cttgcttggt ctgctactgg catcctttgg
    12841 acaatggacg ggagcccttg cggtattttt gatcatcggc aagttgatga gaatagatat
    12901 ttcgatgctt tcgatctatc ctatgttcat gattgctaca ttgataggaa tgctgacgat
    12961 ggtcccaggt ggaatgggga cttttgacgt tttgatgatc ttaggaatga gtcaattgtc
    13021 tgttcggcaa gatgtagcag tagtttggct attatattat cggttgtttt attatgttct
    13081 accttttatg acgggacttc tattgttcat cacacataca ggagtcaaaa tcaatcgatt
    13141 tttagataac attccgcgac tgtttttcca aaaggttgcg catatcgtgc tcgtaagtgc
    13201 tgtctatttt gcggggatca tgatggtact tctatcaaca atcactaatc tgtctgcaat
    13261 cagtcggcta tttcaagtat tattgccgtt ctcattcaat tttttagatc agacagtgaa
    13321 tctattggtt ggctttttat tactcggcct tgctagagca ctttcagtaa aagtcaaaaa
    13381 ggcatttctg cctacgattg ctttactatc ttttggtatt ttaaatacaa tcacacgtac
    13441 gttatcttgg cagttgatat tggtatatgt cttgattctg ttagctgtgt ggttatccag
    13501 aaaagaattt tatcgaacaa aattcgttta ttcttgggga gctataatct ttgatgctag
    13561 cttgttcggc tttttgttta tcgtttacgc aattgcaggc tatcacagcg gacgcttttt
    13621 agtcggtcga ataacaggaa atcattttat tttgtttcct tcagatgatg tgtggttctc
    13681 agggcttatt ggtttgggca tctcattgct agctttagtg gcgctttatc aatatttagc
    13741 tgaagatact acgaagcttg gcagtgagta cgaaaaagac cgttttgacc gtttattgga
    13801 aacatacgga ggcacagcta caagccatca gcttcgcttg tcaggttaca gttattttta
    13861 ttaccaagaa gacgaccaag atcaagtcgt ttttggttat cagatcaaag gaaacaaatg
    13921 ctttgtttta ggagatccag ttggcaatcc taaaatgatg cgggcagcaa cgaatcagtt
    13981 tatgaaacaa gcagattgtt taggctatca gcttgcgttt tataagatat cagaaagcta
    14041 cgtagtgatg cttcatgaat tgggttttca cttcacgaaa gtaggtgaag cagggattgt
    14101 tgatctagca acagaagact tgtctcggct gagtcagcaa cttgaatatc aacgtttgat
    14161 gaaagaagga taccatttta cttggtacga tcaactgccg gaagaattac atcaagctgt
    14221 aaatgaagtt tcacaaaaat ggcttcaagg tgcacgagaa aaatacttct ctgtgggacg
    14281 atttgataaa tcatatgtat tatctagcgg tgtcggtatt gtccgtaaag atcaaaaagt
    14341 cgttggcttc atcaccgctc agccgatgac gaagaagcag gcgggatatg atttgttgcg
    14401 ggtcttacct aaagaatctg aggaattagc tgactatctg ttagccaatc tgtttattgt
    14461 atacgagaaa atgggctact cggaagccaa tctaggctta gctccattag ctaatgttgg
    14521 agaaacagat ttttctttct ttcaagaaaa agtcatgcat atcgtatata attatggtaa
    14581 ttttttctat tccttccagt ctgcttatga aaagaaatta aaatatgtcg atcattggga
    14641 aggacgttat tttgcttata ggaaaggaag taatttcgga tttgctacca tgcagctact
    14701 cagtctgata ggaaaagaaa aaggaaatgt tccgagtttg gcagaagaag tgctcacaga
    14761 attataagaa tcactagaac ttgtttggat tatgaagaga aaattctgtg aaagctgttg
    14821 aaacgatgac aaaatcaacc actaggcaga cataagctat acttttattt ttccctatga
    14881 tagaatactt gcgacttaga cttttcgaat gggtgagagg atggaattga ttgaaaaagc
    14941 gccagccaag ataaatttag gactggatgt attatataga cggcaagatg ggtatcatga
    15001 gttggaaatg gtgatgtcga gcgtagactt ggcagatcat ctattttttg aagaaataac
    15061 agaagacaaa atcattgtag aaacaaataa agcattttta ccggtagatg aacggaacaa
    15121 tgtttatcaa gctgctttat tgctaaaaaa taaatacaat atcaaaaccg gtgtcaagat
    15181 ctttgttaag aagaatattc cagtagcagc tggattaggc ggaggaagta cagactgtgc
    15241 agctgctcta agagggatca accaattatg gaatctgggc tgttcgttag aagaactggc
    15301 agaaatcggt ttggaagtcg gtacagatgt tccttactgt gtctacggaa gtacggcatt
    15361 tgtcggtggc aaaggggaag aaatccaagt attaccttct atgccacagt gctgggttgt
    15421 gttggtcaaa ccaagaatga gtgtctctac acgtacagtg tttagagaag tagatacgca
    15481 agccatccaa catcaagaca tccacggact tgctgaagcc atccgagagc aagattatca
    15541 gcagatgatc aaaaaaatgg gaaacagttt agaagatata acgggaaagc ggcatccagt
    15601 catccatcaa atcaaagagc gtatgatcaa gtacggagca gatgctgcat tgatgagtgg
    15661 aagcggacca accgtttttg ccttgtgtca acattattca agagcgcaga gagtatataa
    15721 tgggttaaaa ggtttttgtg aggaagttta tttagtacga accctgcaat aaaatataag
    15781 aagtaaaata ggtgatgaaa aactgaggaa tcctaaaatg gtattcttca gttttttatt
    15841 gtagtgaaat ggctagatat gagcagcaac tcatccattt tacgatttaa tcaagaatat
    15901 acatgcttaa atcagaaatt gatggatttc tattgactgt gtttttttat tttgatacat
    15961 tagttcacgt taataaatcg taaaattccg atttgttcat tgaaaggagc atataaatga
    16021 aaaaatatct tttgacagct acggtaatga taggtgcttt actgtttgca gcatgtggaa
    16081 atacgaacaa ggaagcagac aaaaaagagg atttgacgat cgttacgact ttttatccga
    16141 tgtatgattt tacaaaagag atcgtagggg atgaaggaaa cgtgaaactt ttgatccctg
    16201 ctggaacgga gccgcatgat ttcgaaccaa gtgcaaaaga aagagcagaa atttccgatg
    16261 cagatgtttt cgtgtataat agttcagaca tggaattttt tgtggattcg ttaaaggatt
    16321 cagtggatag caaacagacc ttgatgatcg aagcagctaa aggaatcgac cgtttagaat
    16381 cgcaagaagc agacgaacat gaagaatcag aagaagggca tggtcattca catgaatacg
    16441 atccacatgt ttggctcgat ccggtattag ctataaaaga agtcagaacg attgctgaag
    16501 aattaggcga aaaatatcca gataaaaagg aaacttttac gaagaatgcc gatgcttata
    16561 tcaaaaagct tgaagcactg gatcaaaaat actccgatga gctaaaagat gcaacaaacc
    16621 gcacatttgt cactcagcat gctgcttttg cttatttagc gaatcaatac gacttaaaac
    16681 aagtagcgat ttcgggcgtt tcaccagatc aggaacccac accaagtcgc ttagctgagc
    16741 taaaagaatt tgtgaagaaa aacaacatca aagtgattta ttttgaagaa aatgcctctt
    16801 cgaaggtagc tgagacattg tcgaatgaaa caggagtgaa gctagaagtg ttgaatcctt
    16861 tagaaagctt gactaatgaa caaatcaaag caggcgaaaa ttatatttct gtcatggaaa
    16921 aaaatctgaa agctttaaaa gaaagtatca attaagtttt agaatggagg ttgtaaggtg
    16981 cgttatatcg aaatatctga tttgaccttt tactatgatg atgaacctgt actagaagat
    17041 gtctcttatc atgtagatgc gggtgaattt gtcattttaa ctggagaaaa tggagcagcc
    17101 aagtcaacct tggtgaaagc atcgttagga ttactgaaac cttcaaaagg aatgataaag
    17161 attgctgaga aaaatcaaga aggaaaaaaa ttaagtatcg gttatattcc tcaacaagtt
    17221 gcatctttca atgcaggttt tcctagtacg gtgatcgaat tagtccgttc aggaagatat
    17281 ccaagaggcc gctggttcaa gcgtctctct gaaaaagatc atcaacatgt acagcgtgct
    17341 ttagaagctg tagggatgtg ggatatgcga aatcggcgaa taggtgaatt gtctggcgga
    17401 caaaagcagc gaatcagttt agcgcgtatt tttgctactg accctgactt atttgttctt
    17461 gatgaaccaa caacaggtat ggatgaagaa tccagaaatg aattttatcg tcttctccga
    17521 catagtgcgc atgtccatgg gaaatcagtt ctaatgatca cccatgatca tgaagatatc
    17581 aaacagtatg cggacagaca gatccgactg gtgagaaagg aggattctca atggcgttgc
    17641 tttcatatga attcatgaga agagcgtttc ttgccgctat cttcattgcc ggaatcgccc
    17701 cgatgctagg tgtgttttta gtgatcagaa gacaatcgct gatggctgat acgctttctc
    17761 atgtctcttt agcaggggta gcgttaggat tctttttgaa ccttaatcct acacttacga
    17821 ccatgctagt cgttgtatta gcagctgtga tattggagta tctgcgaacg atctaccgaa
    17881 cctattcaga aatctccatt gccattttaa tggctggtgg tttggcgcta gcgttagtat
    17941 tgatgaattt gagcggaggg aattcagcaa caagtatcca atcctatctg tttggttcga
    18001 tcgtgaccat tacatgggag caagtcatct ttttaggaat cttattcgtt gccatcggta
    18061 tattgttctt tttattcaaa cggccgatgt atgttctgac ttttgatgaa gataccgccc
    18121 acgtggatgg gctacccgtt catttgatgt cgatgatgtt caatgtgatt actggtgtgg
    18181 ctattgctgt gatgatcccg attgccggtg cacttttgat atccgcaatc atggttcttc
    18241 ccgcagcaat cggtatgcga ttaggcaaaa gcttcaatgt cgtgattgct atcagtgttt
    18301 gtgtaggatt tctagggatg ctgtcaggac taactagctc gttttatcta gatacacctc
    18361 caggagcaac aatcacatta gtctttattg ctttgttcct gattgtaaat atcatcaaac
    18421 gaatattggt tgccttcaga agaaaaaata actaaattat aaagaaaaga agccttataa
    18481 aaacgaaaaa ttttttatag gcttcttttt attttaataa ataccgaact attttcttat
    18541 tttttcataa aatgctcgaa tttttgaaga aaaacttata taatgtaaaa cgataaaatt
    18601 tcttaaaagg agttggaata ggtgaaagta cgtcgcagtg aacgtctagt tgacatgaca
    18661 cagtatttat tgaatcaccc gcatgaattg atttccttaa caagctttgc cgaacgttat
    18721 gaatctgcta aatcttctat cagtgaagat ttgggaatca tcaagaaaac atttaaagaa
    18781 cgagggtatg gaaccttgga aacaatcccg ggtgctgcag gtggtgtatt gttcatccct
    18841 gaaatttcat atgaagaggc gaaaaaatat attgaatctc tagcagaacg tctatcagaa
    18901 caagaccgtc tgcttccagg aggatatgtt tatctctctg atttgttagg agaacctgaa
    18961 ctgctgcgtc aagttggaag aatcattgct tctaaatacc ttggtgaaaa aatcgatgct
    19021 gtaatgactg tagccacaaa aggcgtacct attgcccaag ctgtgtccta ttatctgaat
    19081 gcgccattcg ttattgtacg ccgggactca aaaataacag aaggatcaac agtaagtgtc
    19141 aactatgtgt ctggatcttc tgaaagaatt gaaaagatgg aactgtctaa gagaagtttg
    19201 aaacgtggtt cacgtgtcct tgtagtggat gatttcatga aaggcggcgg aacagtcaac
    19261 ggaatgaaga gcttgattga agaattcgaa tcagaacttg ttggcatcac tgtatttgcc
    19321 gaatcaaaat tcaacggtca tcgcgccatc gatgattata cgtcactgct ttatgtcaaa
    19381 gatgtagata ctcaaacgaa aaatattacg gttgtgccag gaaattattt ttcagaataa
    19441 gaggttgtga aaaagccgct tagtttcgag tagtaagaaa aattttgtga aaatggcttt
    19501 ccacattttt tcataaattt ggcttaatac cgagaaactg gcttttgaac accgtttatc
    19561 tagaggttgt gaaatcagcg tcctgtcctg agtattagct caataaacgg aaaaattgct
    19621 cctcatattt tgccgtttat tgagctaata ccgaaggtca gctgattgaa aaacgtttaa
    19681 tgaagaggtt gtaagcctac cgtttaactc taagtcacaa gaaacgattt caaaaaacag
    19741 cttttcatgt tttatgagta gtgtgacttg tgaccgagga gttggcagga gagcaccggt
    19801 taccaaatag ataggcccgt tatggtctat ctattttttt atccagaaaa cgctgggata
    19861 aaagaaaatc acttgttttg ttgaaaaaat gggtatactg ggataaactg aaatcagcaa
    19921 actatattta ggagtgacgc agttggacgc acgttatgca attattttgg cggcagggaa
    19981 aggtacccgc atgaagtcaa aattatataa agttttacat cccgtttctg gtaaacctat
    20041 ggtagaacat atcattaatc gggtcagtga aacgaaacca gatgaagtga ttacgatcgt
    20101 tggacacgga gcagaacaag ttaaagcaca actaggagaa cgcagtaaat atgcgttaca
    20161 agcagaacaa ttgggaacag gacatgctgt tttgcaagct gcttctttct tggaaggaaa
    20221 aaaaggaaca acgttagtta tcagtggcga tacaccatta ttgactactg aaacgctgaa
    20281 caatcttttt gaatatcacc aaggaaaaaa tgcaagtgca acgatcttga cggcacaagc
    20341 agaaaaccca acaggatatg gacgaatcat ccgtgaccat attgggatcg tagaaaaaat
    20401 cgtggaacaa aaagatgcaa caccagaaga agctcttgta caagaaatca atacaggaac
    20461 ttactgtttt gacaacgaag ctttgttcga tgcgttaagc aaagttggaa caaacaatgc
    20521 tcaaggtgaa tactatctaa cagatatcat cgaaatctta aaagaagaag gccatacagt
    20581 tgctgcttat caaacggatg attttgaaga atcaatggga gtcaatgatc ggatcgcgtt
    20641 agctaaagca aatgagatca tgagaaagcg aattaaccag atgcatatgg tcaatggcgt
    20701 aagctttgtc gattcagcaa cgacatacat cgatgcaggc gtagaaatcg gtccagacac
    20761 attgatcgaa gcaggtgtac aaatccaagg aaatacagtc attggttctg attgtgtcat
    20821 cgggtcacat tcaaaaatcg tagacagtag gattgaggat cacgtcgtca ttgaaaactc
    20881 agtcattgaa agcagccatg tcaagaaaca tgcagatgtg ggaccttatg cacatttacg
    20941 accaaaagct gaaattggcg aaaacgtcca tatcggaaac tttgtggaag tgaaaaatgc
    21001 tcaaatcggc aaaggaacta aagtcggtca cttgacttat gttggtgatg ctacgctggg
    21061 agaagaaatc aatgtcggat gtggtgttgt cttcgtcaac tatgatggaa agaacaaaca
    21121 tcatacgact gtcggcgacc acagctttat tggttctagc acgaatatca tcggacctgt
    21181 cgaggtagct aaaaacagtt cgattgctgc cgggtcaaca attacagaca atattccaga
    21241 atatgcgctg gcaattgcga gagcaagaca agtcaataaa gaaggatatg caaaaaaact
    21301 cccttatcta aactaagact tttgcaaaat cacttgattt atttaaaaaa tatgactact
    21361 atttattagg tagaattcta gagttgtgaa aaagaaagtg gaggtcccca tgtcaaaaca
    21421 ttactttgac ccaagattaa aaatttttgc gttaaattcc aatcgcccat tagcagagaa
    21481 aattgcagca gcagtcggcg tcgagttagg aaaatcatct gttactcaat ttagtgatgg
    21541 agaaattcaa gtaaacattg aagaaagtat tcgtggatcg catgtctatg ttattcaatc
    21601 aacgagcagc ccagtcaatg ataacttgat ggagttgctg atcatgattg acgcactgaa
    21661 acgagcaagt gcaaaaacaa tcaacgtagt catgccttat tatggctatg cgcgtcaaga
    21721 ccgtaaagca cgtgcacggg aaccaatcac agcgaaatta gtagcaaaca tgattcaaaa
    21781 agctggtgca acaagaatgc tgactttgga ccttcatgca gtccaaatcc aaggtttctt
    21841 tgatattcca gtcgatcatt tgatgggtgc gccacttatt gccaattatt tcttagaaaa
    21901 aggaatcaaa ggcgatgatg ttgtcgttgt ttcaccagac catggtggtg tcacacgggc
    21961 acgtaaatta gcggaatttt tgaaatctcc gattgcgatc atagacaaac gccgtccaaa
    22021 agcaaatgtt gcagaagtaa tgaatatcat tggacaagtc aaaggcaaaa cttgtgtact
    22081 gatcgatgat atgatcgata cagcaggtac gatcacattg gctgccaatg ctttgaaaga
    22141 agctggtgca actagtgtgt atgcttcatg tacacatcca gtattatccg gccctgcttt
    22201 acaaagaata gaagattcag ctatcgagcg tctagttgtt acagactcga tctatcttcc
    22261 agaagatcgt aaaatcgaca aaatcgatga agtaagtgtt ggcggactaa tgggagatgc
    22321 aatcaaacgt atccatgaaa acaaaccagt tagtccattg tttgaaacaa aaaataaata
    22381 ataaataaac tcacaaaggg gagtccaatt gggctgagat tgaatctatt tctaaaccct
    22441 tcgtacctgt atcggttatg cgagcgtagg aattgtgaat aaacagctgt ttgactattt
    22501 tcgaaagctg cttcctcctt tgtgactttt ttattcaaag gaggaagttt ttttatggga
    22561 aaaaatagag tttgggtaga aggaacgatt gttgcagcgt tagcgatggt gttgtcgttg
    22621 attccgatcc agatcggcag cagtttttct atttcattag ggcagattcc attgactctt
    22681 tttgcgttaa gaagagggac aaaggcaggg atgctggcag gtttcatttg gggcatccta
    22741 cattttccgt tgggacaagt ttattattta agtgtcgttc aagtgttgat tgagtacccg
    22801 attgcctata cttttgcagg cgcagcaggg ctcatggctt caaatgtcca aaaaggctat
    22861 gtagacgata atacgaaaca aattagaaaa agcatcgtgt ttggtgcatt gattggcgca
    22921 ctttccagat atttttggca ttttattgca ggagtggttt tctggggagc gtatgcacta
    22981 tgggggatga atccttggct cttttctttc gtaatgaatg gtgccagcgg gttgagtaca
    23041 gctattgtaa cgatcatcgt tttattaggg atccaacaaa cgactccttc gatttttgtg
    23101 ccagataaac gacaggagct gtaaataaaa aagaagcaag aaacttgaga cagaatcatg
    23161 tcctagtttc ttgtttcctt tttatttttt gataagaaat agatctactt caatggcaga
    23221 taagaaagat cggcatcttc taccaattgc cagtgtcgat cggtgacaga gtagattaaa
    23281 gtagcgatga tttcctcttc tcgataccgg gtgcctttta atttccaaat ataatcttca
    23341 atcacataga ttgggatacg atatttacca tcgatcaaac caacttgatc aaaagaaaaa
    23401 atgatccctt cctgcatcaa attacgcatt tctttcaata attccacact gattttttca
    23461 acaggtgttt cttttttgaa aaaagatttt tttacattga tcttatctga caagatcgaa
    23521 cttaatttac tagcaaaaat cctataaaat tcatctaaat agcgataata aatccgattc
    23581 agctgatcat taagatcgaa gtatacaaaa ttattctgta gtttataaaa aaacggcgaa
    23641 tgaagatgtg ttttcatatg accaaaatat aataattctg aaatttctaa aggtgtcaat
    23701 tctttcagca tcgttaaatc agtaaagtcg atccacttca attcatcgaa tccacgcctg
    23761 ttacgagaag aggaaaagaa acgctgaata ttttctgtac cacggattac tttcagccct
    23821 gtatgggatt catattctcc agcagaagca gatggatcaa gcaagagcaa gttttgagga
    23881 aaatgcacga tactgtttgc aaagtcagta gcagtcagcc cttttgttaa aacagcatta
    23941 cttgtggtat caatatgtac ataaactgac tcagtcatca tgttcctcct cttatttcct
    24001 cttaatctct tttattttac aacatttgca ttaaaaaagc ttgtttcttt tattttaaaa
    24061 ttccattaca aaatcacgtt ttcattgaaa acactctcat tttcaattaa tttttgtgat
    24121 ttttgtattt ttttatttaa aggaggtttt atgaattgtt ttcttatgga atctacaaag
    24181 tcgaatacga gactcatgac ctttttatga cgtactggta tacttgaaga aaaaggagag
    24241 cgcgatggag ataaaaaaag tttacttttc acagaaaatg tcgctgtatt cgcctatcca
    24301 gcaagcaaaa caaccccttc cattttttca aagtcatcaa gaaagtagag acgctttttg
    24361 gcgttctgca aaaaagcaat gtgcttttaa agcagtatcg aaaaaatata ccgtctattt
    24421 tactattgct aaaagtagag gagatgttat ttttaataat ctgttgattg aaggtgaaac
    24481 ttttgaatgg aaaaaatttt ttcggtatat ggaagcttgc gctcgttttt ttattaaaga
    24541 aaactgttgt tttttatttc aatctcctct atcagaagaa tggttgcgta tttttcataa
    24601 aaacggctat caaggaacca cacaattaaa taaaaagctg gtctatcata cagcacttgt
    24661 tttaggtgga ggaggagcgc acggtgctta tcagattggt gtgtggcagg cgctgaagga
    24721 acatgatatc aactttgaga ttatcacagg tacctcggta ggtgcgttga acggcgcatt
    24781 gattttacaa ggagatatga aaaaagctgt gaatttatgg aaaaagctgt cgacaagaca
    24841 agtgcttgcg ttaccagaaa tggctgcagt tgaagacctt cgtgaacgct tctatcgaga
    24901 aagacgccaa atgacgaaaa cagcactaat tgaaggcggg gtttcttctg ctccattgga
    24961 aaagatggtc aaagacaatt tggatttgtc cttactcaaa cataatccca aaatacgttt
    25021 atatacggtg tctactaaac tgccagaact agcggaagta gtgactgata tccaacagac
    25081 aaaaacagaa gaaataccag attggatact cgcctctgct tcattttatc ccgctatggc
    25141 ttatcgaaag atcggaaaaa ataaatatgc agacggtggg tatcgcaaca aaatacctat
    25201 tgatattgcg attaacaaag gagcaacaga ggcatttgtc gtagatgtgc aagggccagg
    25261 cccagcgaaa aaaattcgta tgccagacat ttttatccat tggaaatgtc aaacattgtg
    25321 gacactaggc agctttctgc tttttgatag ccaaaggaac caattaaatt tacaattagg
    25381 ctatctggaa atgaaaaaac gattaggcta ttactatggg aactggtata catttcattc
    25441 tgttaaacct gcaagaacat actggcgagg atttttgtct tacttaacaa aagaaattca
    25501 gttagaatta tcttttttca aaagcataaa attttggcaa aaactgcgta atttatataa
    25561 gaacagggtc gtaccagaga catgcggatt ggcgatgcta gaacttttag caaaaaaaca
    25621 ttttttactg cccaatgaaa tctatcaagt agacatgatg attcaaatga tctgccaaca
    25681 agatataaaa agtatgccgg atgatttatt ggcacaaatt ggtcaattaa gtactgaaga
    25741 atggcgaagg tatcgaaaat accagcaaaa aatacaaaat gagcgcacga aaactgttta
    25801 ttttgattat ctgctacaag gaaaacgcaa ggatcgtttg cagcatgaat tgcttaagca
    25861 accagttgac acattactga tcctatattt atattatctc aaggaggaac aaccatggca
    25921 caagaatttt catatgaaat cgtagaagaa atcgctatat tgtcagaaaa caacaagggg
    25981 tggcgtaaag aactgaacct agtcagctgg aatggtcgcc cgccaaaatt cgatcttcga
    26041 gattgggcgc cagaccatga aaaaatgggg aaaggcctga cattgacgaa cgaagagttt
    26101 gaacaactgc aaaaagcaat agaaaatatg taatgaggaa ggaccctgtc gaatgaaaag
    26161 tatgactggt tttggcaaag ccatccgcga aacaaaagcg tatcagttag atattgaaat
    26221 aaaaagtgtc aaccagcgtt ttctagatgt tcaaatacga agtcctaaaa tcctgaactt
    26281 tgttgaaaac gattttcgtc agcttattaa acagcagtta agccgcggtc gaatcgaagt
    26341 atttgtgaat ctagcttata ttggcaaaaa cgaaaaacag atcgtcatca actgggaatt
    26401 gattgattca cttatcactc aattgacaga cggaattcaa caacgatacg gtagtcaaaa
    26461 tcaagtgtca attagtcgga tggcggaacg cttcgtgctg gacgaaaact tcgtaacggt
    26521 agaagaaaaa ccggaagaga gcatggaaga attggcacag ttagctctag atacattgaa
    26581 aagcgcactt gattctattg aggcgagtcg agaaaaagaa ggtcaagctt tagctttagt
    26641 gttgaaaaag aatactgaag aattcaaaga agtactaaaa aaactcgata gttttgtaga
    26701 aatctatgaa aaggaatttc aaataaggta tcaaaaaaag ctggaggaat ttcttggagc
    26761 gaaagtcgat gagcaacggt tgttgacgga gctagccatc ttgttggaac gcggagatat
    26821 tcacgaggaa ctggatcgtc tggcgatcca tgtacaaaaa ctagatgaac ttatcgaagc
    26881 acaatgtcct gtaggtcggg aattagattt cctgatccaa gaaatgaatc gggaaatcaa
    26941 cacgatcggt tccaaatcaa atgcaatcga aattaaaaat caagtcgtcc agtctaagac
    27001 gatcttagaa aaaatcagag aacaagtaca aaatattgaa tgacgaaaga ggtagagata
    27061 atgaaatatt atgacgtaac gttccacgaa ttaagtggaa aaactgtggt taaacgggat
    27121 atcccttctg aaaaaaacgg ctttgacgta tggaaagatg cctgtgcaga ctataatgag
    27181 aacgaactgt ttattttgat caacgacggt gcttacgtga cgatgaatcg gaaatttatt
    27241 gttcgaattg acacagaaga ggtagaagat ccgacagaaa aagcacgttc tcgaaaagat
    27301 gagatcatgg gtgtagtgaa tactttgtcc aatatgggct tttagcaagg atgctgaaca
    27361 aagaaataca ataaataaac agaattggat ttcttcgctt agcttctttg ctctaggaat
    27421 acatttaaag gttgtgacaa aattcgtgtc acaatctttt tttattttga ataagtgatg
    27481 ttcaaaaacc attttctcgg tattaagcca aatttatgca aaaatgtgag aaactatttt
    27541 cacaaaattt ttcttcatac tcgaaactaa tcggcttctt cacgacctct tatacacggc
    27601 gttcaaaagc ttgcatctgc gataataacc ccaaccaaac gaaaaacatg agaagctgtt
    27661 tatgtttggc tgttcttatt acttgatgca ggacagcttt tttacgacct cttggtacag
    27721 ggtagctttt ttaccaattt ctagctataa ttaaagataa ccttgaaagt tgcagaaaaa
    27781 aagtgcaaaa taaacgataa gtacaaaaag actagttgaa aggacgtcgt catgtcagag
    27841 cgtggattat taatcgtgtt gtctggtcca tccggtgtag gaaaaggcac agtacgaaaa
    27901 gcaatttttg agagtgagga taatgatttt cagtattcga tctcaatgac tacccgtaaa
    27961 atgcgtgaag gggaggtcga aggcgttgat tatttcttcc gaagcaaaga agagtttgaa
    28021 tcaatgatcg aagctggaga gatgctggaa tacgcagaat atgtcgggaa ttattatgga
    28081 actcctttgt catatgtcaa caagacattg gatgaaggaa aagatgtttt cttggagatt
    28141 gaagtccaag gagcaaaaca agtcaaagaa aaagtgcccg atggtgtatt catctttttg
    28201 actccgccag atttagcgga attaaaatca cggatcgtag gccgaggaac agatgcagat
    28261 gaagtaatcg aaaaacgaat gaaagttgca aaagaagaaa tcgaaatgat ggctctttac
    28321 gactatgctg ttgtaaatga tgaagtgccg ctagcagttg aacgaatcaa aaacattatt
    28381 gccagtgaac attttcgagt agatcgcgta atcggtaaat atattaaaat gttaaaggag
    28441 atgtagtctt atgatgttaa aaccttcaat tgactcacta ttagatcgtg taaattcaaa
    28501 atattctcta gtgattttag caagtaaacg cgcgcatgaa ttggatgcaa gtgcacagcc
    28561 tactctagat tcttttgatt cagtaaaaag cgtcggtcaa gctttagaag aaatcgatgc
    28621 aggaaatgta gtcaatgatc cacatcctga attaaaacgt gaacgtttga agatggaaga
    28681 agaggaacgt caagcacaaa aagagcgtga acaacacgaa ttggaatcac gtatccgtga
    28741 agagcaaaaa atgtaataaa gaaaaataga gcgaacatct aaaaagaaaa gcaaacccag
    28801 ctgtttcctt ttcaaacatt cgccacttat tgtctggtag aaaaggctgt gtctgaactt
    28861 tttgacacag ttcttttttt tcttatctgc tgttaatttt ttgttaggat ttggcagaag
    28921 ataagacaaa tccatcgatc tctagtaaaa taggcaagga actttttgtc gcttgataag
    28981 aaaagacaaa aaaaggagga aacgaaccat gacattaaca gctgaagtca ttgtggacgt
    29041 acctactatg cagaccgatc agccattcac ttatttggtt ccctctgaaa tggaaacagc
    29101 tttgcaagtc gggatgcgag tagaagtccc ttttggtaat ggcaatcgtc atgtccaagg
    29161 atttgttatg gctatccaaa aatcagaaga atcagctaat ccatctttga aggcagttat
    29221 tcgtttgcta gaccttgctc cggtggtcaa tgaagaatta ctttcattag ctgattatat
    29281 gaaaaaaatt acttacgcat tcaaaatcac ttgtctacaa acgatgcttc cgagtgtgat
    29341 gaaagcagaa tatgataaat tgatctatcc tttggcagac acaccagaag ttcaggtatt
    29401 gtttgatcag cgagaagtga tttcctggaa ggaagcagaa gaagaaggca gcctttctca
    29461 attgattcgc tggcgccaag agcaattagt agatatcaaa tatgaagtcc atacacgaaa
    29521 taaagtaaaa acgattcgtt tggtccgttc tttgttaact gaaaagcaaa tcgaagaaga
    29581 atgggcaaaa ttacggcaaa atgccaagaa acaaaaagaa cttcttttgt gtttatctga
    29641 actgagccaa gaagaaccaa ttgcttattt caaaaataaa ggaatcagta ctgctgtctt
    29701 gaatcaagga aaagaaaagg gctggctgga gtttatagaa tcagaacgtt atcgcgaccc
    29761 ttataaagac cgagtatttg accaaacgac ggcattggaa ctgaatgcag aacaaaaaaa
    29821 tgctgtcgaa caaatcatca cagcaggtca gcagcaaaaa gatcaggtct ttttgctgga
    29881 gggaatcact ggcagcggga aaacagaagt atatcttcag gcaatcgctg atgttttgtc
    29941 agaaaataaa acggctatta tgttagtgcc tgaaatcgca ttgactccgc aaatggtcga
    30001 gcgattcaaa ggacgcttcg gagaatcagt tgcggtctta catagcggac tttcccaagg
    30061 tgaaaaatat gatgaatggc gcaagattga gcgggaagaa gcgcaagtag tagtaggcgc
    30121 acgatctgct atttttgccc cgctgaaaaa tatcgggctg atcattatcg atgaagaaca
    30181 tgaatcaagt tacaaacaag atgagacacc gcgttatcat gcgagagatc tagcaatttg
    30241 gcgcagtaaa tatcatcatt gcccaatagt tctaggaagc gcgacgccct ctttagaatc
    30301 aagagcacga gctcaaaaag gcgtttatca gttattgcag ttaaaccacc gagccaaagc
    30361 agctgcacag cttccagcta ttgagatcgt agatatgcgt gaagagtttc agaatcatcg
    30421 gacctctact ttttctgcta atttgcagga aaaaatacaa aatcgattag acaaaaaaga
    30481 acaaactgtc ctactgctca atcgtcgagg atattcgtct tttgtgatgt gtagggactg
    30541 tggatttgtt cttccatgtc ctaattgcga tatctctctt acactgcata tggatacacg
    30601 ttcaatgcgc tgccattatt gcggacatga agaacctatt cccaatcgct gtcctaattg
    30661 tggcggcaat aaaatccgct actatggaac aggtactcaa aaagtagaag aggaactccg
    30721 agaactttat ccgcaagcta ggattttgcg tatggatgta gataccactc gaagaaaagg
    30781 ggcacacgaa cagattttac aaaaattcgg tgcaaaagaa gcagatatat tattagggac
    30841 acaaatgatt gctaaaggtt tggactttcc agaagtgaca ttagttgggg tgttgaatgc
    30901 tgatacctcc ctgaatttac cggattttcg ttctagtgag catacattcc aattgcttac
    30961 ccaagtttca ggacgagcag ggcgagcgga aaaagcaggc gaagtcgtga tccaaacatt
    31021 caatcctcaa cattacgcca tagaattggc taaaaaacaa aattatgagc agttttatca
    31081 gcaggaaatg catgtacggc atcgtggagg ctatcctcct tattacttta ctgtgaaaat
    31141 aaccgccagc catcctgaag aacaagtagc ggcaaagaaa atctttcaga ttgccaatca
    31201 gctaaaagaa gtgttaagcc ctcaaagctt gctattaggg ccaacgccca gcatgatttt
    31261 gagagtgaaa aaccgatatt attatcaact aatcatcaaa tataaacatg aaccgaatct
    31321 tcctcatgtt ttggatgaaa ttttgaatgg aagccagaaa gaacagcgac aaggtctttt
    31381 tgtggcaatt gacaacgaac cattaaactt tatttaagaa agggccaaat tatgcgctat
    31441 cctatattga tccaccctaa tgataaatta aaaagaactg ctcagccaat cgatgtaatc
    31501 acggacgaga caatcgcttt attagacaat ttatatgaga caatgattgc gaatgacgga
    31561 atagggatcg ctgctcctca agtaggacaa aacaagagaa ttgctgtgat cgaagtagat
    31621 gaaggcgaga aatttgaact gattaaccca gaaatcatcg aagcaaaagg tgaaagcctt
    31681 gacgtagaag gttgtctcag tattccgcat gtctatggaa cggtcaagcg agcagatgaa
    31741 gtgaccgtgc gttattatga tcgagacgga gaagagatag aagtgacggc ttttggctat
    31801 ttagcccgtg ccttccagca tgaaatcgat cacttagacg gtatcttgtt cattgagaaa
    31861 atgatacagc agatcccgga agaagaactt gaagaatata tggaggaaca tcttgatgac
    31921 taagctagta tttatgggca cacctgcttt ttctgtgccg attcttgaag ggctgataga
    31981 atcaggttac gagatccagg cagtggtaac acagcccgac cgtccagttg ggcggaaacg
    32041 agtaattacg ccgacaccgg taaaaaaagc ggctctgaag cacggtatcc gtgtgctgca
    32101 gccagagaaa atctccggtt cgccagaaat ggaagaaatc attgaattgg tgcctgatgt
    32161 gatcgtcact gcggcatttg gccaattctt gcctgaaaag ttattgcaag taccaaaatt
    32221 aggggcaatc aatgtccatg cttctttact tcctaaatat cggggaggtg cgcctgttca
    32281 ttatgccatc atgaatgggg agaaagaaac tggtgtaacg atcatggaaa tgatcaaaaa
    32341 aatggatgca ggcggaatct atgcgcaaga aagcatacca atcactaaac aagatgatgt
    32401 agggacgatg tttgaaaagc ttagcctttt aggaagaaag ctattgctag aaacattgcc
    32461 caatattttg gatggacaaa aaccagtacc tcaagacgag tcagaagcaa ctttttcgcc
    32521 aaacatcaca cgggaacaag aagcaatcga ttggcataaa actgcagaag aaattgacaa
    32581 ccaagtacgc ggaatgcgtc cttggccaat tgcattcacg acctatgagg gcatacgctg
    32641 gaaattatta tcggttgaag tattggcaga aactacagac aaagcacctg gtacgatcat
    32701 ccggaaagac aaaaaaaatc tatggattgc ttgcggtaaa cagaccgtct tagccatcaa
    32761 tgaattacag ccagctggta aaggaaaaca ggccgtacat gatttcctta acggaagcgg
    32821 tcagcaagtt cagattggtc agcaggtgaa ataatgaaaa aaatccctaa aaaaatgaaa
    32881 aaatcagtac gatatatggc attactgaca ttagagcgag tgaacaaggg tggcgcctac
    32941 tcgaatcttt tgttgaatga gatgatcaaa caaagcgagc taaatcaaaa agatgtgggt
    33001 ttatttacag aattgatcta tggtacgatt agccatcagc gactattgga attttacgtt
    33061 gcaccattga tcgctaaagc aaaaaaagtg gatgactggg tcaagatgct tctttatctt
    33121 tctgtatacc aattagaatt tttagataaa gtccctgcac atgctatttt aaacgaggcg
    33181 gtcgaaatcg caaaagtaaa aggaaatcct gggacaggga aatttgtaaa tggtgtcttg
    33241 aggaattatc agcgtcaagg agcaccagat ctgcaaggca ttgctgatcc tatcgaaaga
    33301 ctttctgtca aaatcagcct gcctctatgg atgacgaaac gactggtgga tcaaatcgga
    33361 tacgaagaaa ctgaaaagct cggtttatcg ctatatcagc ctagccatgc tagtgcccga
    33421 gtagatacac gccgactttc cagagatcag gccatcactg ttttgcaaga agaagagatc
    33481 acagctgaaa aaagccaagt cagtccatac ggtatagtag cgaaaaaagg gcatttagct
    33541 tctagctcat tgttccacga tggcgtcatg acgatccaag atgaaagttc gatgcttgta
    33601 gcgccgtcta tgcaaatcga gcctgaacat catgtcttag atgcctgtgc agcacccgga
    33661 ggtaagacga cgcatattgc ttctttttta gatccgtcat gcggtggaga agtggtcgct
    33721 ttagatgtac acgaacacaa agtcaaactc attgaagata atgcagcacg tctaggtgtc
    33781 tcttctgctg tctacgctca aaagatggat gctagagaag tcagtaaaca gttcgaagca
    33841 gagcagtttg atcggatttt agtagacgcg ccttgttcag gtcttgggct gcttcggcga
    33901 aaaccagata ttcgttataa aaaacagccg gatgaattag cgaatttacc aaaaatccaa
    33961 ttggaaattt tagaaagctg cgcaccaact ttaaagtctt ccggtattct gacttatagc
    34021 acttgtacga tcttaaaaga agaaaaccaa gacgttgttt ctgctttctt ggaaagacac
    34081 cctgattttg agaggattga tgttttgacc aatcctatgc tacaatcatc aatcgaagag
    34141 aaaatgttga ctttgtatcc gcatcagttt tacacagatg gatttttcat ttgttgtttg
    34201 cgcaaaaagt aatgaggtga aaaaatgcag attgaatatc aatcagatgt aggaagacga
    34261 cgtaacacaa atcaagacta tgccagtgta tttaccagcc gttcaggtct caagcttgct
    34321 gtattagcag acgggatggg tggtcatcgt gccggagaca ttgccagtca gatggcggta
    34381 acgaatctag gcgaagcttg ggaaaaacaa gaagctgttg acgatgaaaa aatcgcccaa
    34441 tggttcattc aatcgattca agaagaaaat atgctgattt atcagcgtgg acaagaacag
    34501 ccggaatata acggtatggg aacaacaatc gtagcggccg ctctgtcaga tgactggttc
    34561 acgattgcca atgttgggga tagcagagct tatttgattc gtgaagataa aatcatgcaa
    34621 ttgacggagg atcattcttt agtcaatgaa ctagtcaaat caggagaaat cagcgaagaa
    34681 atggcagtga accatccaag gaaaaatatt ttaacacgtt ctgtcggcat gcctggaaca
    34741 gtcgaagtag atgtttctac tcatctttgg caactaaaag atcgactgct gttatgttca
    34801 gatggcttga cgaacatgct gtctgaagaa gaaataggaa cgatcatcaa tcaagaaggc
    34861 ccattgtctc ataaagtaac tgagctgatt gatcgtgcca atgaagcagg cggagcggat
    34921 aatatcaccg ttcttcttat cgaatataag gaggacagtg tatgatcgag ttgggcaaaa
    34981 aattaaatgg ccgttatcaa atcactggaa atatcggtag cggtggtatg gcaaatgtat
    35041 ttttggcgca cgatttaatc ttggatcgtg atgtagcagt taaagtctta cgatttgact
    35101 ttcaaaatga ccagactgcg attcgacgat ttcagagaga agctttagca gcaacagaac
    35161 tcgttcatcc aaacattgtt agtgtttacg atgttggtga agaagacaac atgcagtatc
    35221 tggtgatgga atacgtcaaa ggaatggact tgaaacgata tatccaaaca cattatcctg
    35281 ttccttatga aacagcagta aatattatgc agcagatcct ttctgctatt tctttagctc
    35341 ataaccatca aatcatccac cgagatttga aaccccaaaa cgtactgatc gataatgaag
    35401 gtgttgtaaa aatcacggat ttcgggattg ctatcgcttt atctgaaaca tcgatcacgc
    35461 agacgaatac gatgctagga tctgttcatt atctgtcccc tgagcaggcc agaggaagta
    35521 tggcaacgaa gcagtcagat atttatgctt tagggatcat cctttatgag atgttgacgg
    35581 gtagcgtacc gtttgatggt gaatctgctg taacaattgc tttaaaacat tttcaagatg
    35641 atcttccatc tataaaagca cttgatccaa atgtgccaca agcactggaa aacgtgattt
    35701 tacgggcaac ggctaaagaa cctgcagacc gttataagtc agccgaggaa atgtctgatg
    35761 atctttctac agtattatca ccagctcgtg caaacgaaga aaaatggcag cctcatgtga
    35821 tggataatga aacaaaagtt atcacacccc ttacggaaga tgcaccaatg cctgattcat
    35881 tcaaatctat gcctctgcca aaagacaagc cagaaaacga aaccttacca gaggaggaag
    35941 aagttctgcc tgatcctaaa aagaaaggac agaaaaaatg gtggctgatc ctattagcta
    36001 ttcttgctgt tttaggaatc ggaacagctg tattctttgc ttctggcggg cgaggagaag
    36061 ttgttgttcc tgatgtttct gatctttctg aagcttctgc tagagaaaca ctcgcaaaag
    36121 cgaaattaga agtagcaaca aaaacagaag aaattgcaga tgacaaaatc gaagaaggta
    36181 atgtagtgaa gacagacccg gcagcgggaa cgacagtcaa gcaaaaacgc gaagtcactc
    36241 tgtatattag tagcggcacg aaaaaaatca aattagatga ttacagtggt aaaagttatg
    36301 aagatgccga agcaagtttg aaagaattag ggttttctgc tgacttgatt caaaaagaag
    36361 aggaattcag ttcagaggta gaaagcggaa tgatcatttc gcaatctcca tcagaagata
    36421 cagaagtcga tcctaaaaca gacacgatta ctttcacagt cagcaaagga ccagaaacag
    36481 tgactttgag tagtcatgta ggagaaaact acgaaactgt tcgtaattgg cttgttacac
    36541 aaggattcaa tatcaataat attagtgcta cttatgacta tagcgacact gtaccatcag
    36601 gttcgatcat cagtcaggat ccagcctcgg gtgaagttgt agcagaagaa acttacatca
    36661 attttgtcgt aagccaagga acagagccta aattgaatga tatctccggc tatacaaaaa
    36721 gcgaagcaca aagttattta gctagtgtcg gtgcagaata tatcgggcat gagacttccg
    36781 aatattcaaa cacggtggat aaagataaag tgattcgtac agtaccaggg gcaggaacga
    36841 caattaccaa aggaatggtt gtgaacgtaa tttactctaa aggaccagat ccagcgtctt
    36901 ctagttctga aaaagactct tcagacagtt ctagcagctc aagtagctcc agtagcacaa
    36961 gcaactcttc aaaagaagaa tcttccagct ccacaagttc atcagctagc acctcagaaa
    37021 gttcaaaata agtgctgaat aaaatatatc agaagggaat gcgacattga tttgttgcat
    37081 tctctttttt gtgtttctat ctcttttgat caattttcaa gccatatact ttgagaagtt
    37141 tgcatggaat aacacctact ttcctcttcg tatggtaaaa taaacaaaaa cggaggtggc
    37201 acttatcaaa ggacaaatca gaaaagcaat cagcggtttt tactatgtat acgcaaacgg
    37261 agagacctat caaacaagag gaagaggaaa tttccggaat cggaaaatca cgccgcttgt
    37321 cggagatcag gtgatctttg agagtgaaaa tcaaacagac ggctatcttc tggaaatctt
    37381 gccgagaaaa aatcaattag ttcgcccacc agtcacaaat gttgatcttg gaatcattgt
    37441 cacaagtatc gtagagcctg cattttctta taatctactt gaccgctttc tagttacctt
    37501 ggaatacgag tcgatcgaac cgattatttt tttgacaaag accgacttgt cagacgaccc
    37561 agaaaaaatc gaagagatca agcaaaccta tactaaaata ggctatccgg tgattgtacc
    37621 caatcatacg ggtgatacga cagaactgat ccgttacttc ccagaacggc tatcggtctt
    37681 tatgggtcag tctggagcag gaaaatcgac gctactgaat caaatatcac cggaactgaa
    37741 tttagcaaca ggagagattt ctgatgcact tggaagagga cggcatacaa cacgtcatgt
    37801 ggaactgatt cctatctatg gcgggttagt agcagataca ccaggattta gctcgattga
    37861 ctttttgaca attgaagcag gagaactgcc gagacaattt cctgaatttg tagaagcttc
    37921 tgtccattgc aaatttagag agtgcatgca tgctaaagaa cctggctgcg aagtaaaaca
    37981 tagagtagaa acaggtggta tcgcacagac acgttacgac aattatttgc aattcttaca
    38041 agaaatcgaa aaaagaaaac caatgtatgc aaaaaaagaa ggtaaacgaa aataggagga
    38101 aacaagaatg aagatagcac catccatttt gagtgcagat tttgccaatt tacaaagaga
    38161 cattgagtta gtggaaaaag gaggcgcaga ttacatccac gtagatgtaa tggatggccg
    38221 atttgtccca aatatcacat tagggccaaa tattgttcag gcaatccgtc ctgttactaa
    38281 attaccgtta gacgtccatc tgatgatcgt tgatccagaa aactacattc cagcatttgc
    38341 aaaagctgga gcagatatca ttactgtcca cgtcgaagca actcctcata ttcatcgggc
    38401 acttcaaatg acaaaaagct taggagttaa agctggagta gttatcaatc caggaacacc
    38461 agtctccatg atcaaacatg ttttgccttt ggctgatcaa gtactagtca tgactgtcaa
    38521 tcctgggttc ggcggacaaa gctttattga agaaacagta gaaaaaatta cggaactcgc
    38581 tgatctacgt agagagaaca attggactta tgcaatcgaa gtagatggcg gaatcgttcc
    38641 agaaacagca aaaatctgta aagatgcagg ggcggatgtc ttcgttgcag gatcatatat
    38701 ctatggagcc gaaaatccag tcggacaaat cgaacgatta aaagaggcat tagactaaat
    38761 gaaaatttta ttagctgctg gaggtaatcc gcaaaactgg ccgcagtctc tgctgtccaa
    38821 atacgatgcc tatgtcggga tagaccgtgg tgcgctgtac ctgcttcaag caggctaccc
    38881 agtagatctg gcagtgggtg attttgattc attgtcgaac gaagagcaga aggaagtatt
    38941 tgcaaaagcc aaagagtata cccgttcccc tgcagaaaaa gacgatacag atacacagtt
    39001 aggtatctta aaaacatttg aacgttaccc gcaagcggaa gtcactttga ttggagctac
    39061 gggcggaaga ttggatcatc ttttagccaa tctctggtta ggtatggaac ctcgcttcaa
    39121 accctttgcc catcagctta ttatcagaga ttgtcaaaat tatttgtctt attatttgcc
    39181 tggagagcat atagtaagac agataccaga tatgaagtat ttagcttatt gctgcttgac
    39241 tcccgtctcg aatcttacat taaaaggcag caagtatgta ttggaaaata aagaagtaga
    39301 atatccgaca tcttatgcaa gtaacgaatt tctttcagat accgcagaat tttctttttc
    39361 agatggtatg attgcagtta ttcaaagcaa agattgatcc ataaacaaat aaaaaaattt
    39421 gtctttcagg ctaaaaatga cagaatctat tatttgctaa aaaaaagctt aagaggagca
    39481 acttaccttt tgtttcacgg catttagtga taaaattgaa cacaagagtc taattaattc
    39541 gaggtgtctt tgtgaagaag ttcaatccta ataaaaatat tattattacc ttggttattg
    39601 ttatcatcgt ggtgacgata ctaagtgtga ccgctgcgca gcgagcgaat gaaggaaagc
    39661 ccaatttctt ccaatccatc gttaatgaca gtgttgcaat ggttgataaa acaatctctg
    39721 ccccagtacg gtgggtacga aatggagtag attctgtcca taatcttttt tcaacttatg
    39781 ccgaaaatga gcggctaaaa gaaaaaatcg atagctatga tgacgtttca cagcaaaaca
    39841 agaattacga gagagaaatc gaagcgttga aaaaagaact tgagttgaat cagacgctga
    39901 ctagttacga aaaagtaacg gcaaatgtca ttactcgttc gcctgacagt tggcaggaca
    39961 tgctgatcgt agacaagggt tctaaagacg gtatcgaagc aaatatggca gtcatgtcgc
    40021 aaaaaggatt gattggccga gtgatcgagg tcaatacggc ttcgtctaaa atcgaattac
    40081 tgtcatcctc taatgaaagc tccaatcatt ttccagtacg ggtatcttcg gctaatggcg
    40141 aagcgtttgg tttgcttaaa aactatgatg aaaagctcca tgccttagtg gtgacccaat
    40201 taactggtga tacggatatc aaagaagggg atgttgtcca gacatccggt cttggaggga
    40261 attctccagc taacttgccg atcggtacgg ttattaaaac gaaaccagat agttatgggc
    40321 tggatcggga agtttatgtg aaaccttatg cagaaatgta tgacgtgtca gttgtgacga
    40381 ttgtccaacg gctagcggag gattagtcca tgttgaagaa agaaacaatg aagtactatc
    40441 tgccaatcgt tttgttcttt ttgatgttga tagatggtca tttaacaaga atgctagggg
    40501 agtggtcgaa aggcacctat atgtcaaatg cccactttct gatattggca ttattatgtt
    40561 gcagtatggc gtttgaaaaa cgttatttac tgattaccac gattgttctc ggggctatct
    40621 atgacgctta ctatattggc gttatcggta tctatgcagt agctctccct ttaattgtat
    40681 ggttgatgta tgtaatgaaa gacgttatcc atgtcaacat ctttactgaa tttttcagta
    40741 tgatcatctt tgtcacgggt tatgaattgt ttacgatggt ggtccagttg atttttaaat
    40801 tagcagtagt aaataacacg tattttatta caaggttttt aggacctaca ctgctgttga
    40861 acatgattat atttgtatta ttcatttttc cctttaagaa attattcagt gatgaataat
    40921 ttcttttttt atttttaggt cgaaagcgaa aaagaatcgt tgttatctta agaaatgcta
    40981 gacttaacgc ggctttttca tgatcatttt ctgaaacgaa cagttttgtc atttttaaaa
    41041 gttgttttga aacatttttg taacataact attatatcgt tgacacactg ctatggtaca
    41101 atttttatat cgttaagaaa gacttaaata tatttagata tttattaaat taagccagtc
    41161 ggaggaatga agagtgaaaa agagtttaat atcagcagta atggtatgtt caatgacctt
    41221 gactgccgta gcatcaccga tcgctgccgc ggcggacgat tttgattctc agatacaaca
    41281 gcaagatcaa aagattgcag acttgaaaaa tcaacaagca gatgcacaat cacaaatcga
    41341 tgccttagaa agccaagttt ctgaaatcaa cacacaagca caagacctat tagcaaaaca
    41401 agatacattg cgtcaagaat ctgcacaatt agtaaaagac attgcagatt tacaagaacg
    41461 tattgaaaaa cgtgaagata caatccaaaa acaagcacgc gaagcacaag taagcaacac
    41521 aagctcaaac tacatcgatg ctgtattgaa tgctgattca ttagcagatg ctattggacg
    41581 cgttcaagca atgacaacga tggtaaaagc aaacaacgac ttgatggaac aacaaaaaca
    41641 agataaaaaa gctgtagaag acaaaaaagc tgaaaacgat gctaaactaa aagaattagc
    41701 tgaaaaccaa gctgctttgg aatctcaaaa aggcgatctt ttatctaaac aagctgattt
    41761 gaacgtactg aaaacttcat tagctgctga acaagcaact gctgaagaca agaaagctga
    41821 cttgaaccgt caaaaagcag aagctgaagc agagcaagct cgtattcgtg aacaacaacg
    41881 tctagcagaa caagctcgtc aacaagctgc acaagaaaaa gctgaaaaag aagcacgcga
    41941 acaagcagag gctgaagcac aagctactca agcttcatct actgcacaaa gctcagcaac
    42001 agaagaatca tcagctacac aatcttcaat gactgaagaa tcatcatcag ctacacaatc
    42061 ttcagcaaca gaagaatcaa caacacctga atcttcaaca gaagaatcaa cagcgcctga
    42121 atcttcagca acagaagaat caacaacagc gcctgaatct tcagcaacag aagaatcaac
    42181 aacagtgcct gaatcttcag caacagaaga atcaacaaca gtgcctgaat cttcaacaac
    42241 agaagaatca acaacacctg cgcctacaac accatcaaca gatcaaagtg ttgatacagg
    42301 aaacggcaca ggaagtagta ctccggctcc aacgccaaca ccaacacctg aacaaccaaa
    42361 acctgtaaca cctgctccag ctccttctgg aagtgtgaat ggtgcagcaa tcgtagcaga
    42421 agcttacaaa tatattggta ctccatatgt ttggggcggt aaagatccaa gtggctttga
    42481 ctgctcaggg ttcacacgct atgtttacat gcaagtaact ggtcgtgaca tcggtggttg
    42541 gacagttcct caagaatcag ctggaacaaa aatttcagtt tctcaagcaa aagctggaga
    42601 cttgttattc tgggggtcac aaggcggaac ttaccacgta gcgattgctt taggcggagg
    42661 acaatatatc catgctcctc aaccaggcga aagcgtaaaa gttggttcag ttcaatggtt
    42721 tgcccctgac tttgctgtca gcatgtaaga atga
//
LOCUS       DAFLVO010000018        41707 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.018, whole genome shotgun sequence.
ACCESSION   DAFLVO010000018 DAFLVO010000000
VERSION     DAFLVO010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41707
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.018"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(12..617)
                     /gene="dhaL"
                     /locus_tag="L1U99_001002"
     CDS             complement(12..617)
                     /gene="dhaL"
                     /locus_tag="L1U99_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HBN1211559.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(645..1655)
                     /gene="dhaK"
                     /locus_tag="L1U99_001003"
     CDS             complement(645..1655)
                     /gene="dhaK"
                     /locus_tag="L1U99_001003"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HBN1211560.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(1630..2076)
                     /gene="dhaM"
                     /locus_tag="L1U99_001004"
     CDS             complement(1630..2076)
                     /gene="dhaM"
                     /locus_tag="L1U99_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HBN1211561.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            2179..2499
                     /locus_tag="L1U99_001005"
     CDS             2179..2499
                     /locus_tag="L1U99_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBN1211562.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(2611..3480)
                     /locus_tag="L1U99_001006"
     CDS             complement(2611..3480)
                     /locus_tag="L1U99_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBN1211563.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(3576..4880)
                     /locus_tag="L1U99_001007"
     CDS             complement(3576..4880)
                     /locus_tag="L1U99_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1211564.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(4877..5386)
                     /locus_tag="L1U99_001008"
     CDS             complement(4877..5386)
                     /locus_tag="L1U99_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211565.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(5561..7696)
                     /locus_tag="L1U99_001009"
     CDS             complement(5561..7696)
                     /locus_tag="L1U99_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1211566.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(7779..9434)
                     /locus_tag="L1U99_001010"
     CDS             complement(7779..9434)
                     /locus_tag="L1U99_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBN1211567.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYFSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(9436..9750)
                     /locus_tag="L1U99_001011"
     CDS             complement(9436..9750)
                     /locus_tag="L1U99_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBN1211568.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            9920..10180
                     /locus_tag="L1U99_001012"
     CDS             9920..10180
                     /locus_tag="L1U99_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBN1211569.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            10194..10508
                     /locus_tag="L1U99_001013"
     CDS             10194..10508
                     /locus_tag="L1U99_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBN1211570.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(11238..11792)
                     /locus_tag="L1U99_001014"
     CDS             complement(11238..11792)
                     /locus_tag="L1U99_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBN1211571.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(11918..13847)
                     /locus_tag="L1U99_001015"
                     /pseudo
     CDS             complement(11918..13847)
                     /locus_tag="L1U99_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(14153..14869)
                     /locus_tag="L1U99_001016"
     CDS             complement(14153..14869)
                     /locus_tag="L1U99_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBN1211572.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(14870..16693)
                     /gene="glpO"
                     /locus_tag="L1U99_001017"
     CDS             complement(14870..16693)
                     /gene="glpO"
                     /locus_tag="L1U99_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HBN1211573.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(16707..18203)
                     /gene="glpK"
                     /locus_tag="L1U99_001018"
     CDS             complement(16707..18203)
                     /gene="glpK"
                     /locus_tag="L1U99_001018"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBN1211574.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(18339..19799)
                     /locus_tag="L1U99_001019"
     CDS             complement(18339..19799)
                     /locus_tag="L1U99_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1211575.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(19789..21084)
                     /locus_tag="L1U99_001020"
     CDS             complement(19789..21084)
                     /locus_tag="L1U99_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBN1211576.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(21416..22093)
                     /locus_tag="L1U99_001021"
     CDS             complement(21416..22093)
                     /locus_tag="L1U99_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HBN1211577.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(22123..23214)
                     /locus_tag="L1U99_001022"
     CDS             complement(22123..23214)
                     /locus_tag="L1U99_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HBN1211578.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEKAYKELYLPSPLYNFLKARYQ"
     gene            complement(23315..23749)
                     /locus_tag="L1U99_001023"
     CDS             complement(23315..23749)
                     /locus_tag="L1U99_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1211579.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(24333..25790)
                     /gene="ascB"
                     /locus_tag="L1U99_001024"
     CDS             complement(24333..25790)
                     /gene="ascB"
                     /locus_tag="L1U99_001024"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBN1211580.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(25787..27682)
                     /locus_tag="L1U99_001025"
     CDS             complement(25787..27682)
                     /locus_tag="L1U99_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1211581.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(27740..29515)
                     /locus_tag="L1U99_001026"
     CDS             complement(27740..29515)
                     /locus_tag="L1U99_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBN1211582.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(29565..31061)
                     /locus_tag="L1U99_001027"
     CDS             complement(29565..31061)
                     /locus_tag="L1U99_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1211583.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(31255..32877)
                     /locus_tag="L1U99_001028"
     CDS             complement(31255..32877)
                     /locus_tag="L1U99_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBN1211584.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(33205..34518)
                     /locus_tag="L1U99_001029"
     CDS             complement(33205..34518)
                     /locus_tag="L1U99_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBN1211585.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(34763..34987)
                     /locus_tag="L1U99_001030"
     CDS             complement(34763..34987)
                     /locus_tag="L1U99_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211586.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(35007..35429)
                     /locus_tag="L1U99_001031"
     CDS             complement(35007..35429)
                     /locus_tag="L1U99_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HBN1211587.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(35571..36281)
                     /locus_tag="L1U99_001032"
     CDS             complement(35571..36281)
                     /locus_tag="L1U99_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211588.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(36299..36796)
                     /locus_tag="L1U99_001033"
     CDS             complement(36299..36796)
                     /locus_tag="L1U99_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1211589.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(36833..37285)
                     /locus_tag="L1U99_001034"
     CDS             complement(36833..37285)
                     /locus_tag="L1U99_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1211590.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(37420..38025)
                     /locus_tag="L1U99_001035"
     CDS             complement(37420..38025)
                     /locus_tag="L1U99_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBN1211591.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(38475..39095)
                     /locus_tag="L1U99_001036"
     CDS             complement(38475..39095)
                     /locus_tag="L1U99_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBN1211592.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(39097..39966)
                     /locus_tag="L1U99_001037"
     CDS             complement(39097..39966)
                     /locus_tag="L1U99_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HBN1211593.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(39989..40396)
                     /locus_tag="L1U99_001038"
     CDS             complement(39989..40396)
                     /locus_tag="L1U99_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBN1211594.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(40415..41704)
                     /locus_tag="L1U99_001039"
     CDS             complement(40415..41704)
                     /locus_tag="L1U99_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1211595.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
BASE COUNT        11760 a         8983 c         7021 g        13943 t
ORIGIN      
        1 ttttattgaa cttaaggttg attgatcaca tctaaaagcg ttgaaaataa aatggcacta
       61 gaagcagctc ctgggtcgat atgtccgatt gcacgctctc ctagatagga agctcgtcct
      121 tttttagcta ccaagacttt ggtgtgttct tttgcctggt caatgatttc ttttgttaaa
      181 ttccctgcct tcaatgcctc tgtgactggc agccaaacat ctaacatcgt tttatcgtca
      241 gcttctgcct ttcctcggct ttgaataccc gctgttccct gctcgatcac ttcgcctaat
      301 ttttcttgag aatcaataga atcgacctct tttgtcgctt tcatcatgtt catgaatgca
      361 gatccgtata acggaccaga agccccaccg actttcgata tcatcgccat agagaatact
      421 ttgaatgtat cgctgattgt ttcaggatga tcggcttgaa aagcttcttc ataagctgaa
      481 acccctcttc ccatgttatt tccatggtct ccatcgccaa tcggggtatc tagatcactg
      541 agatattgtt tgttctgatt gattgcctct gcaaattgcg tgagccattc ttggatttct
      601 tgaacggtta gtttcatatt atcacccttt tatcttgaga ttttttacca tgaaatcgtc
      661 tgtacattgc tttctaaaga atctttccat tgtgtctccg tcaagtcgat cagtgttaga
      721 gaaagacctt gcatatctag tgaggtcata aaattaccga cttttcggaa aactacattg
      781 acgcctcttt cttccaacag agctaaaaca tcattcatga acacgaactg ttccatcaaa
      841 ggcgtcccgc ccattccgtt gactagtaca cctgcttctt ttggtaaatt cgagtaatca
      901 tctaaaatct tagtaacaag ttcctttgcc agtactttag aaggctgcat cttttctcga
      961 cgatagcctg gctcaccgtg gataccaaca ccatactcga tctcatcttc tcctagttcg
     1021 aatcctggtt tccctacttc tggtacagtt gctgctcgaa gcgctagacc gatcgtctta
     1081 gttgcctgta cgaccttttc tcccagttct ttcaactcag ctagggaagc accgtttctt
     1141 gctgcatcgc ccacgatttt gtgtacaagg acagtacctg caactccgcg ttttccagca
     1201 gtatacgtac tattttcaac ggcgatatca tcatctacga tcacactttc tacttcaata
     1261 tcgtccatag cagctaattc ctttgccata tcgaagttca atgcatcccc tgtataattc
     1321 ttaacgatca gcaaaactcc ttttccacta tcggcttcct taatagccgt ctgaatctga
     1381 tctggagttg gagaagtaaa cacatcacca agcaccgctg cacttaacat cccttcccct
     1441 acaaacccgg catgggatgg ttcatgtccg cttcctccac cagaaaccaa accaacttgt
     1501 tccgctttct gattcttggc tacaacacgg gaagattcta cacgatgaac aagttctgga
     1561 tagcttttta ctaatccttc cagcatttct tcgacaatat tgcttggatc attcatgatt
     1621 tttttcaatt tattcccatc ctttctttcc ggcattttgt gcttctgtta agatttgctg
     1681 agtatcatct gttataccgg cagtgatggc tgctgcaaaa gctccttcca ctaaaggcgc
     1741 atccaccaga tgataacgtt gctgctgctc ttcttccaac atgtcttttg ccagttccga
     1801 gttcaatacc gcgctaccga tatccgcaaa aacaaaataa ctagctgcat cgcttgattc
     1861 attgactgct tctacgattt tcatcgggtc tgatccgatc tcgccattta ttccgccgag
     1921 agaaaaaatt tgcacctctt cggatttttg catctgctca atcatttctt taataccatc
     1981 tgttactttt tgactatgag aaataagcaa aatacttttt ttcacaagaa tcttcctttc
     2041 ttttacatag ttgctaacga ttggtttcgc tttcattaat gaacaattca agtatataat
     2101 aaatttctaa ttttgggaaa atatgtgtag tgcttcttga agtttgttat actttaatta
     2161 aaagagagga gtgatcgaat gattacaaca acaacgaaca gtgtagaggg aaaagccgta
     2221 gtagcttata aagggatcgt ttttggtgag gtcattactg ggatccatgc atttaaagac
     2281 ttggaggcgg ggttgcgaaa tatctttggc ggccgctcaa aaagctatga aaacgaacta
     2341 atgggtgcaa gagaagaagc acttgccgaa atggccgaac gtgcaaaagc attaggagct
     2401 gatgcgatca ttggcgtaaa aatggactat gaagtattag gcagcgacaa tggcatgctg
     2461 atggtcacat gtagtggaac agctgtctcc acgagataag taggggacat ctgttttaat
     2521 aactaaagag agatgggaca tgtagtggca ctcaagaatt agatttttca gtctaacttc
     2581 gaggtactct accttcccat cctctctttt ttatttcttt ttgcggatga ttccgtaagc
     2641 tgctgcgact aacacacccg cccctgctaa ggaataactg acagaagctg ttttttcatt
     2701 tgtttttggc aaagtctgac ttgttgattt ggatggctct gtcgtttgct gaactgtttc
     2761 tgtcgtgctt ccagaggtca ctgatttttc tcctgccgaa tgcaaaatat cttttattcg
     2821 ttggaaacta gctgctaagt cagctttttt tgcttcaaaa tcattagcaa ctgtttgtgc
     2881 ttcgctgatc tttccgtgga ttgcttgact ggccgctgtg atatccgctt gagtttgact
     2941 tagctttcca gaagctgttt gagcaacctg atttaattgc tgattgaatt cttttgcttg
     3001 ttggatcttc ccgtcaagat ctgtttggac agcttccgct tttgctttcg cttcggcaag
     3061 ctttttctca agttgtgcac ggtcatttcc cactttattt ttaagatcag ctaaatcttg
     3121 atcgattgct gcttggtctt ctttcaattt gttttttgca gcttctaatg cttcttcgag
     3181 ttcttttctt ttattttcca agtcttgcaa atgatcgatt tggtcagaag aggtagaact
     3241 atttattgat gtatcttctg aagatgaaat cgtttctcct gaattatctg tcggtacatt
     3301 ggaagtcatt tctgtttccg aggcaccgtt ttcagcacca gaagagctta tggttgttga
     3361 aggttctgtt tgagcaggtt cagaagtttc cgcaaaagct gtctgtccca ataagaaaat
     3421 actggaaaca gcaattggcc agattaacgg cttcattctt tttttcatca cttttcccat
     3481 ccttactact ttttaactaa tttcttatta taagcaaaaa tgtttggaag aaccataaac
     3541 acaacaggct gtttgtctaa aaaacggtgc atcttttatt tttttgtacg ttccgggctt
     3601 ttccatgtcc cgcttccata acctaaaatc gttttgactg ctggaatgaa agtcgtcacg
     3661 atcgttatcg cgttcactat ccagaacaaa agcatatata gtggtgcgaa aagaaggtat
     3721 ttcaattttc ttcgtcgatc atctacaatc agcgaagcta gcaactggaa aaatcctgcg
     3781 accatttcaa agcagatgaa cacaaaactg aatgtaaaag taatataaat ctgttcgtag
     3841 tttccttgat atacataatg cccgattaat ccagcaaaaa gaactacgga aatacaaaag
     3901 aatattgacc agacaatact caatgtttga tcaatgaaga tgatcgttct tccaatatgt
     3961 ttaaaaggat ggagcatcac ttttttgaaa ttcgtcagcc agacttctgt tccacctttt
     4021 gcccaacgtt ttctgtgtcg atatagcatc ttcaacgtca caggtacttc catgaaaaag
     4081 ataatctcag gagcaaaaac agataaccag tcatttaact gatgatccca agcaatactg
     4141 atgtcttctg tcgctcgatc ttgtctgaat ccgcccacat cgatcaaggc ttcttttcga
     4201 tacatcgtat ttgctccact gtacgcataa agaccaccga aaacagctga ctgtgttcgt
     4261 ttaatgatgc ccacgatact tgagaattca accgtttgag attttgcaat caatttggta
     4321 cgattttgga catccatatt tgcagtgacc gcagcaatat gtcttgcacc agggcgaatg
     4381 aaataattca catacctaat cagtgcatct ggctccggta ccgtgtctgc atcattgctt
     4441 aaaatcaatt tcccttttgc aaaggcaagt ccgatattaa acgcgtgggc ttttccttta
     4501 tttttttcga tccgaaccac acgaagatta gcgtattttt tcatcagtct agctaatatt
     4561 tctggtgttt ggtccgttga accatcgtct gtcactaata cctcatagtt gtgataattc
     4621 aatttcgtca tcaaatactc gattgtatat tcgatcacaa tttcttcatt atgggctggc
     4681 accatgatcg tgatgaacgg ttcgacactc aagggaacat ctacccattc tttttgctta
     4741 tgtttgtata aaaacacata acaccagaca ccaataaacc atacaaatcc gcctaaaatc
     4801 ggataagaaa cgagaaaaaa atacataata gacaaacaag tatctaagaa taaattacct
     4861 gtatgggtga ttgagatcat ttcagttcca ccccattttc tttatacaaa tctgcaatga
     4921 atgtcgtatc tagatttttc tcttcggaga cagaataaaa acggaccgtt tctctctctt
     4981 cttttgttcc aaaacgttcc gtatacactt cttcaagtaa ttcttgtctt tttttcaatt
     5041 tttcatcttc atattcaaaa gatttattta cttttttgta tagatttcga ttgttccacc
     5101 tagtcaatac aaatgaggta atcaggaaac tgaaaaaaat caatacaaaa aagccgatta
     5161 agaaatacag cattttcttt tctgataaaa aagcgtacaa ggaaaaatcc ttggctcttt
     5221 ctggtctcgt taatgggaaa aagacccata taaaaggaag aacaacgatc atccatccta
     5281 aaagagccac taacgtttgc caaatcttta accagtaatt accttttgaa aaatacttat
     5341 ctttcaccaa aattgatgca acttcttctc ttgttacttt tttcatatcc tcacctcacg
     5401 tttttttgtt acgacgtagg agtttaccat acatttcatt tcttttcaca taaagtgttc
     5461 ctaaattttt cctaagaaaa agaacaaaac atttctcatc agcaaatgaa aaatattttg
     5521 ttctttttat cagttgttct ttttattttt tatctcttaa ttatgttgct ctttccaata
     5581 cgacaatgct tttcattcct ctagatatcg ccgtgtacat ttgtctgcgt cttctttgct
     5641 catctccatc gttttcaaat ggatataaga ttacatgatc aaattccagt ccttttgcta
     5701 gactcaaagg aatgatttgg cagttttcta atccatatga atttttttta atcgattctt
     5761 gtagcgtttg ggtttcctct tctgtttggg tgataactgc cgctttttct ccttttagag
     5821 aaaccaaaat ctcagctagt attttcaaca attcttcaga ggatcgaaaa gagcggtatt
     5881 cgggttcttt tccttgcggt cggatcgata cgatgtcgat cttctcttga tccacagcat
     5941 aggttttgaa aagctctgtg attgctccgc tagaacggta actatttcta agatcatacc
     6001 gatggatcgg cagatggtag tcgtcgaaac aacgcataat atcagcaaaa gtagtggaag
     6061 aattaaagat tgcctgattc tcgtcaccta ctaaagtaaa gtgagttttt ggaaataatt
     6121 cgatcaatag acctaattgt gccagggtat aatcttgtac ttcatcaatc aatagatagc
     6181 gaaatgctgg tacatttacc ttttcaacaa gtaaatgacg aatagctaat ataatgactg
     6241 cttcatcaac agtacgtgtg ggttgccaag cataagctga gccatatcgt ttttcataaa
     6301 ttctttcaaa caactgatgc tcatccaccc atgccatttc ttcgatttgt ctggttattt
     6361 ttcgatattt tttttgtaaa agtttccttg cataagctac aatactttgt tccgaatcat
     6421 cagaaatcaa tttaccgaat aattccaact gcctatcttc tgtcaacgag agtacctgat
     6481 tctgcacagc aggacttttt gcttgtttca aaagatgatt cttccattcg ctcatcagtg
     6541 cctttttcgt tgcttgaagc ctatcgatca atttaggatg agcaggaact ttctcatata
     6601 ttttttcgat cgttttttta gaaaggactg tttttccatt tttagtaagt ccacggataa
     6661 aattcggatg atctaaaaac aaaggatctg attgttttag attatcgata aactttttgc
     6721 tacgcaaacg ttctgtctgc tccgatacat tttctcccgt gatacgtttg aaataagcct
     6781 cttcaccttc tatttcctct gctgaaagct gtgaaaccag ctgtatgatg gttagattca
     6841 gtggatttct ttcacctaat gatggtagga cattcgaaat atagtcgata aaccgatgat
     6901 taggtgatag aatcagcaag tcatcggatg tcatcgtatc tcgatataaa tagagcagat
     6961 acgcaatacg ctgcatgata gcagaggttt taccacttcc tgctacgcca tttaccaaga
     7021 tattttgact tttcacatcc cgaatgattg tgttttgttc cgattggatc gtagcagtga
     7081 tagccttcat ttcattggtc tcatcttggc ctaagacttc taataatacg tcatcttgaa
     7141 tagctacaga cgtatcaaaa aacttgacca aacgatctct ttccaaaaga aattgtcgtc
     7201 tttctttaat aaccgtatcg attttatttt gacgaaccgt ataagaagat ggaccaatca
     7261 tgttattgta aaaaagttcg gcaattggtg aacgccaatc ataaacaaga ttttcatctg
     7321 catcatctgt gaaatttgct gtaccgatat aaaaggattc ttttggctca ttatccagaa
     7381 agtctacaac gacttttcca aagtagggac ttttcaataa acgttcgatc tttgctagct
     7441 gattttctgc gtttttctgt ttgatattca tctgatcgat ttctctattt ttcatttcaa
     7501 tcatcgaaaa agtatccagg ttatctaagt aactgtcaaa attcaatcga agctcgccag
     7561 ccatttcttt caacgactgg tttccttcta tttttgccgt atccatcgat tcccgcagtt
     7621 cgtttttttt atcaattagc ttttgataca cgttcttcag atatgcttct tctaactgtt
     7681 tttgtgtgtt gaccatacac attctcctct ttttttaaag tggtggaacc gattagttta
     7741 cctcttttaa gagtcgaatg caagcttttt aacgagtatc atttgttagg atatatcagt
     7801 tcttcaggtc ggacagtttg atataaagaa aatgcaccat caaggttttt tacgtggtag
     7861 ccagactgct tcaagattct ttccgctaga tagctacgta atccgctatg acagctgacg
     7921 atatattctt gttggctgtc taattcattt aatcggtccc gaagttcatt caaagggata
     7981 tgtttggctt ccttgaattt gcccttttcc aattcttctg ctgttcgcac atctaataaa
     8041 atttttcctt ttgctagttc tgtcggcaat tcatgccatt gtacggtttc actaagccct
     8101 tctgcaatgt tcattgctgc atatcctagc atgtttactg gatctttggc tgagccaaat
     8161 ggcggtgcat acgtcaattc taattccggt aaatcgaaga tcgtcaaatg ccctttgatt
     8221 gctgttgcta aaatatcgat ccgtttatcc acaccttttg ccccaacacc ttgtgcacca
     8281 taaatctcgc cagtctctgg atggaagatc aacttcagta aaatatctgt tgcttctgga
     8341 taatagcttg catgatcttt tcctgataca tgaatgactt caaaagacag ttcgttttct
     8401 ttggctgttc tttcacttaa accggtggat gcggcagtca ttccaaacgt tcgtataatt
     8461 gctgttccaa taccgccttg atttcttcga gaaattccgg aaatcgtgtc cgcaacttgt
     8521 ctaccttgac gattggctgg tgaagcaaga gaaataagtg catcttttcc agtgatttgc
     8581 tgttttacaa cgatagcatc ccccaccgca taaatatcag gaatattcgt ttgataacgt
     8641 tcgtctacta ggataccccc gcgtatgcct aattcgattc cagcggtcac tgctagctgg
     8701 ttatcaggac gaacaccaat ggataaaata actaaatcag cagggatggt acgcccatca
     8761 tccagtcgca atcgtttccc gtggtcttca aatccagcga cagcatgaga agtaatcact
     8821 tctactcctt gatgagacaa ttctttttct ataaaagctg ccatttcttc atccagtgtt
     8881 ggaagaatat gtggtgcttg ttcgatcacc atgacttcta aacctcttct ttttaggttt
     8941 tctgccattt ccaatccgat gaatcctgca ccaacgatca cggcacgctt tggctgtttt
     9001 tctaatgcat gcatcacttt atcgatatct ggtacatttc taatagaaaa aacattgtcg
     9061 gcttctgtta tccctggaat cgatggaaca actggttttg caccaggaga taaaaccaat
     9121 gcatcgtact gttcaatgtg tttttgaccc tcatgtacga cttctaccgt tttgttttcg
     9181 ggaaagatgg ctgtcacttc atgatttgga cgcacatcta aacaaaaacg agcggataat
     9241 gattctggcg tttggacaag aagattttcc cgttcactga tttctcccga aaaataataa
     9301 ggcaagccgc aatttgcaaa agaaacatac ggtccttttt caaaaacaac gatttctgca
     9361 tcttccatta atcggcgaag ccgtgtagca gcagacattc cacctgctac acctccgaca
     9421 ataacgattt tcatcttatt tccctcctac tgttcgatca aaccattgat tcatgccacc
     9481 acgtacattc actacatcat aaccagattt ctttaattct ttagctgctt gtttactcct
     9541 catccctgat tgacaaatca catagacggt cttttctttg tctccatcat atctgtttat
     9601 actttgtaat ggaacatttt tagctccttt tatatgcccg ccccggtatt ctgcaggtgt
     9661 tctaacatca agtaacgctg gattttccaa aagcttttcc tttaattctg ggactgttat
     9721 cgattttatt gattgaaata gcaaattcat tttctgcacc tcatttacat ttttataaat
     9781 acctcatggg gtatattaaa caggagcttt attaatatgt caaccagaat gactcttcat
     9841 ttttttcact actttttata tttgcataaa ataccgataa ggggtattat ctaattataa
     9901 aaatagagga gaatgtgtta tggagattga taataaaaat atcctgaacc gtttgaaacg
     9961 tacagaggga caaattcgtg gtatccaaaa aatgatcgaa gacgaaaaag aatgtatgga
    10021 tgtcatcact caattaagcg ctgttcgttc tagtattgat cgcgtaatgg gcatgatcgt
    10081 tgcagataat ctgaaaaatt gctttgagaa acctgatagt aatccagaag aacaagcggc
    10141 taaactagaa caagcgatca agatgattat taaaaagtaa aggaatgatt tcaatgaaag
    10201 tcgttttcca tattgatgaa ttagaaaaat ggtcagaaac agggaaaaac gtaaaaaacc
    10261 tgataaaagc ttctccagaa acgacgattg tcgtatctgt aaatggcatc gcgattaccg
    10321 gttatctaga ctctgccaat gcagaattct tagatttgca aggagtcgtt tttcacgctt
    10381 gcgccaatgc tatgcgtgct aatcatattt cagaaagttc tttacctgaa caagtaatcg
    10441 ttgtaccagc aggtgtcctt gatttagttg aactgcaatc ccaaggttat gcttatatca
    10501 agccttagtc agtagaggtt gcgacagaag tgatcagctt caagaaattt cggcttattt
    10561 ttcgaagaag ctacttctgg aaaaccgtga atcaaaggtt gtgaaaacgc tgtcctgcat
    10621 caagtaataa gaacagccaa acaaaaatag cttctcatat ttttcgtttg gttgggctta
    10681 ttaccgcaga tgcaagcttt tgaacaccgt ttaaggaaga ggttgtgaaa tcagcggttt
    10741 gacctaagta ttagagaaaa aaacgggaaa atagctcctc atattttgcc gttttttgag
    10801 ctaataccga aggtcagctg attgaacacc gtttaaggaa gagattgtga aaaagtcgct
    10861 tagtttcgag tattaagaaa aattttgtga aaatggattt ctacattttt gcataaattt
    10921 ggcttaatac cgagaaactg gcttttgaat accgtttaag gaagaggttg taaaatcagc
    10981 ggtttgacct gagtattaga gaaacaaacg gaaaaatagc tgctcatatt ttgccgtttt
    11041 ttgagctaat accgaaggtc agctgattga acaccgttta ccaagaggtt gtgagcctac
    11101 catttaactc cgaatcacaa gaaataattt caaaaacaac ttctcctgtt tttggttcgg
    11161 ttggcttatt atcgagaagt agctactggg agtctattta tcaaaaaaag gaatgcgaca
    11221 taggtcacac ccctttttta ttttctttga aacatctttc ggtactcgac agcatacaag
    11281 acaaaagatt gtaaaagacc gtaagtgatg acggcaaaaa tgactctcac ccacagcgtt
    11341 ggtaattctg ggaaaagcag caaaaggatc atgccaacat agatgacagc agtcgctact
    11401 ttgccatacc acttcgctcc acttaatttg atatttttag atagcccgat taatccagct
    11461 acaaacataa agccttcttt tatcaagaat agaccaaaca acagccaaag ccacggtcga
    11521 taccatgcca tagacaaaat cagaaaaagt tgtgtcaatt tatctgcaaa cggatcaagc
    11581 accttcccta agtctgttac ctgattatat ctccgagcaa tgaccccgtc tagataatca
    11641 gacaaacctg agacaacaat gaccgctcct gctatataaa atgactgtct cagcacaaaa
    11701 taaagataaa tcggcagcaa aaaaatacgg aatatcgata aaagattcgg aatcgtttgt
    11761 atttctttac gccagtctgt gcttaatttc attttatcgc cctacctcct cagcactctt
    11821 ttctttttat tttagcttac acggggaata aaaccaatga tttcactgtt tttatttttc
    11881 tttacagaca ctgatattat gagctaattt gagataatca cttgctgttt tcatcgttta
    11941 ctcttctttc ttcctgtcgt ttgcgcattt cttttactag tactttatga gctttttttg
    12001 atcctcgctc taggtcacgc tgccgtttac gtgttttata atcgataaac agactgtcta
    12061 aatcgtaacc tgtcgggtac agatcttctg ctgaacgcac cagacgaaca cgctgacgag
    12121 gcacgtggat tatttttttg tctaaatata catcaatcgt atcttcacct atatcttcat
    12181 aaactaacgc ttctttttgg tattcattga caaatatccg atcacctttt gcaaagagct
    12241 gacgttcttt tttattctcc ttcctatttg taactgctgt cttaggaaga aattcttttt
    12301 tctgtgtccg ataggctttt tccgccaagt aacgctctgc ttgatggatc aatttcatcg
    12361 acatatccat tttatgagca atccacaaag cttggctttc tcctgtttct tccaacccgc
    12421 aactgatatt taggacgaag tgcttcccga tcgaaagcca tagcagccgg cacaaaatct
    12481 tcatgatctc cggcgaattt cttgatttct ccataatggg tcgtggcaat gatcaatgcc
    12541 ccttgctcat acatagattc catgattgcg atcgctagtg cagccccttc atttggctct
    12601 gttccactgc caatctcatc taaaagtacc aacgtattcc tttttatctt tttcaaaata
    12661 gcagcgatgt tttgcatatg accagaaaat gtactcaacg cattttctaa attttggtgg
    12721 tcaccgacat cgacgaaaat ctcatcaaag acagcaagct ctgtcccttc ttttgccgga
    12781 acttgcatac cgaacatcgc catcaaagtc aataaaccga ctgtcttcaa cacgactgtt
    12841 ttgcctccgg catttgctcc ggtgataatc aagcctcgat agtctttacc gatttcaaca
    12901 tccaatggta ccgcatgctc aggtaaaaat ggatgtctgc cttgcttgat aatgatatgt
    12961 tccgatttat tgattctagg tgtgcttcca ttgatttctc ggctaaattt tgcccgagca
    13021 aagatgatat ctaacaccgt gatcgtttcg atcaataaat cgatcacttc ttcgttttct
    13081 gcgatagcac cagtcaatgc cgccaggact tgatattctt cactgatttc ttcagctttt
    13141 aacaactgat agtgttcatt caatttagaa atcacagttg gttcaataaa aaccgtcgtt
    13201 cttttatttg attcatcgat aatcgttcca tctattttat ttttatagct ggctttgata
    13261 ggaatcgtat agtattcgcc tttttgaaca atcattgctt cttggatcat ttctttgttt
    13321 ttcggatgac gcaagaattt cagtaatttt gactggattt ctttttcgat tagttgtaat
    13381 tgtttgcgta ctttacgcaa attacgtgac gcgtcgtcac tgactttatt attttttatt
    13441 ttctggtcaa tcaactcttc tacatttatc aaatcaggaa gatgtttgct ataagcaaac
    13501 aacaagggtg tctggtattg attcttatca aaaaactttg tgatcatccg actgcttcta
    13561 agaaaatccg catattcgat caaatcggtt ggctgcagaa tcaacccttt tttgacttgt
    13621 tctgtcagtg catcgatcct cggcaacccc ataaatggaa catgctgact gctttctaag
    13681 atcaagcgtg cttctcttgt ttcttcttga cgatccaaga cagtttgtag gtttgtcgag
    13741 accgtcatat cgctgattcg ttttttgcta tagtttccaa ttgctcttgc ttggatttcc
    13801 tttttgatcc gatcaaattg taattgacta atcatttcgt tgtccatatt ctctcctttt
    13861 cttgaagaga tacctgtccc aaaataaata agggcctaga gataaataaa aggatagaac
    13921 acagcttaaa aaagtcatgt cctatcctta ttagaataca aagatattgt tttcctgaca
    13981 ggtaccgttt cataagcaca ccaaataaac tttgtttatt ggctattcga cttactgatt
    14041 agataccagc tacactcaca aaacataccc cattcttcta ggtcttattt attttccact
    14101 taactatagc aagacacatt ttggttgtca aactttagta tgttttatag atttacacca
    14161 ttaatgaata gacacctacc gcgataattg ctccgatcat tggacctgcg attggtaccc
    14221 atgaatatgc ccaatctgaa gttcctttat tagctattgg caataccgca tgtgctaatc
    14281 gaggaccaaa gtcccgagca gggttgattg catatcctgt tggccctcct aatgaaagac
    14341 cgatggctaa gatcaatcca cctacagcga atacgttcgt tccaggtgca aattcgtttt
    14401 gtccaaaagc tagcaaccca agaactaata caaatgtacc aattaattct gtgatcacat
    14461 ttgctggata attccgtata gcaggacctg ttgcaaacgt tcctaaaatc gcgctttcat
    14521 ctttcgttgc attccaatgt ggcaaataag aaagccaaac aagaatggcc cctgcaaaag
    14581 ctcctaaaac ttgcgcaatg atgaaaggaa cgacaagatt ccaactaatt gcccctgtca
    14641 tcgccatagc tagagagact gcaggattca aatgagctgg gcccatgaat ccagaaatat
    14701 agacagccat tgttacagcg agtccccaac caaatgcgat gacaatccag ccagaagcct
    14761 gtgctttact tttgtttaaa ttcacagccg cacacacacc atctccaagc aaaactagga
    14821 tcagtgtccc aataaactcc cccatgattt gagtcatatc actgttcatt tatttctccc
    14881 cctttagttc ccgcagatct gattctgcaa tcaatgcttc taaacgttta gtctgttgcg
    14941 ccttctcctc ttctgtccat tcaaaatatc cagcaattgc atcgatcaca ggttgcttga
    15001 tctcatcaag ctgatctcgt tcaaacaaca gatgatttgt acgacgaatg agataatcgc
    15061 ctggggccaa aaccatttct tcttctaaac cataacgtaa ccgagctgac tcagcgagac
    15121 tcaaaccagg ataaggtgcc atttcttttg ctaattcaaa gatacgtcgg gcattagtcc
    15181 cgtaaaaatc agcgatataa gtagcatctt cttcctctaa accggctgct actccttctt
    15241 ttgctaattc tgtcactgtt tcttctaatt tagttggatc gaagtttcca cctgaaatct
    15301 gatatttttt agagtcgatt tctttcgtct ctattccgta ttcttctttt aataattggc
    15361 gtatcaatcg caaagctcct tctgccatct tacggtaatc ggtgattttc ccaccagata
    15421 aagtcagcaa accatctggt tctctttcta aagaactacc tctggaaatc gtagaaggtg
    15481 ctttttcatc acggctgttt tccaaatggt tcaacacgtc ttctacttca gcacgagaaa
    15541 ctttgttttc cttatattca cttactgtat cgacaacttt attgaagctc ttgtctgaaa
    15601 tcgatccatt atctccacca ttgtaatcag aaccagaatt accaatcaac agtggacgaa
    15661 gtcctgccca gcttgcttcg atatcattca atgtgatatt tgcttctgga tagcgatgat
    15721 tgatcacatc caatagataa tctacatctt cttgtgtgac tttcggatcc gtaaaatctc
    15781 cttggtaatc cgtatctgtc gtaccaaagt aagtcttgtt ttctcttgga atagcaaaaa
    15841 ccatccgccc atcttgcttt cctgtatcga agtatgtggg ttgcggtaca ggcagttttt
    15901 tcgcatctac aactaaatgg atccctttag ttggacgcat tttaggagag actggacgcg
    15961 taaaattcaa gtttcgtact ttatctaccc aaggaccact cgtattgatc actaattttg
    16021 ctttgatttc gatcacttca tctgtcagca ggtcacgagc tttgacgcca acgatttgat
    16081 cgccatcata taaaaagcca accgctttca ttttacttac tagataagcc ccatcttcgg
    16141 cagccttttt gatattatca atcactaaac gggcatcatt gttgcggaaa tctagataga
    16201 cacccgcgcc ttttagccct tcttttttca aaaacggttc tctttccaat acttcttctg
    16261 gtgtcagcgt ataattctca tatttggttc ctgtcacatt tgccagtttg tcataaaggt
    16321 ccattgctac tttgaccgag aacatattga aggttgttgc tccttcgccc tcatagattg
    16381 gcaaaagcat tggatctggt tttgggatgt gtggggcaat actttgtacg actgcacgtt
    16441 caccaactgt gtcagctact acttccacat caaatgtctt cagataacga ataccgccat
    16501 gaacaagttt ggtcgagcga gaggaagtcc cttctgcaaa atcctgcatt tcgatcaatc
    16561 ctgttttgat tcctgatgct gctgactgga ctgccacacc ggcaccagtg attccgccac
    16621 cgatgatcaa cagatccaat tcttcttgct gcattttttg aatgctatct tgtcttgtct
    16681 tgtttgaaaa catatggatt tcctccttat tcaaatgctt gggtagcttt tactgctttt
    16741 ttccaaccgt tgtaaagttt ttctcggcgc tcttcctcca tttgaacttc aaatagcttg
    16801 ccagcttcat aaaattcgcg gatctcgtct gtatctttcc aataaccgac agctaatcct
    16861 gctaaaaatg ctgcccctag cgccgttgtt tccaagtttt ctgctcgttg gatcggtaca
    16921 ttcaagatat ctgtttggaa ttgcatcaga tattcattgt ttgctgcacc gccatctact
    16981 ttcaatacag gaatcttgat tccagtgtca tcttgcatcg tatcgatgat atctctcact
    17041 tgataagcaa tcgactgtaa agtagcttta atgatatctt cttttgtcgt accacgtgtc
    17101 aagccaaaca tagcccctcg tgctgcctga tcccaataag gagcacctag cccaacgaat
    17161 gcaggaacaa cataaacctc atcttcgctt gtagagcgtt tcgctgcgtc ttctgaatcg
    17221 ctagcttttt gcaacatttg aagtccatct ctcagccatt gaatcgaaga accagccaca
    17281 aaaatacttc cttctaaagc atagtaaacc tttccattta tgccgtaacc aattgtcgtc
    17341 aataaattat ttttggataa ttgcggtttt tcaccggtat tcatgacaat aaatgaacct
    17401 gtaccataag tattcttgac catgcctggt tcgaatgcca tttgtccgaa taatgcggct
    17461 tgctggtctc ctgccatccc tgaaattggt gcttcgcttc cataaaaatg ataaccttgc
    17521 gtataaccat aaacttctga gttagaagtg acttttggta acatcactcg aggaatattt
    17581 agtaaatcta aaatctcctg atcccaatct agctgatgga tattgaacaa catcgtccga
    17641 ctggcattcg agtaatcagt aacatgtgct tgtccatcgg tcagtttcca tactaaccaa
    17701 gaatcgatcg ttccaaacat caattcgcct ttttcagctc gttcttgcgc gccttctaca
    17761 tgatcaagaa tccagcgtat cttcgttgct gagaaatagg catcgatcac taaccctgtt
    17821 ttttcgtgga aaaattcttg atagccttca ttttttaagt tatctgcaat tccagctgac
    17881 tgtctggatt gccaaacaac tgcatgatag attggacgtc ctgtatcttt ttcccatatt
    17941 actgttgttt cacgctggtt cgttatgcca atcccagcaa tctgatttgg tttgatccct
    18001 gattcgatga acgctccggc aataactgac tgtacagaat tccagatttc atttgcatca
    18061 tgttccaccc aactttcttg cgggaaatat tgcgtgaact ctttttgaga actgccgatg
    18121 tgtcttcctt tcttgtcaaa gataattgct cgtgagctag ttgtaccttg gtcaatcgcc
    18181 atgatatacg ttgattctgt cattgtgatt ccctccatta tatgcaaacg ctttctttaa
    18241 ctactcttat catactactg ttttaaaaaa agaaactgtc aaaattttat tctttttttc
    18301 tttttttgac agttttttat tatgaagcta ttttttaatc aattcttttc ttttttcagc
    18361 gtctctattc ttcttttcaa tcgaataatg tcgtaaggtg acgcaaattc tgacagataa
    18421 tattcacact gttttttgtt tctctggcaa aatgtgatca ccaaatcata ttctttacct
    18481 tcttcataac ttccaatctc aataccgccg attcccctca gttctctgat cagatattgt
    18541 tgaaaagcaa tacgataaat cggcagactt tctaaatcga ttccaatcac tactggtttt
    18601 gcaatataaa aatcgatcat caaaagaaca ttggcatact ggatcatcag gtaactaagc
    18661 tcactatctt cagctctttt cctcggcaat tgctgcaccg ctgtttcctg taatttcgcc
    18721 agtaactgtg ttaaggaatg cccgagcatt ttctgctgct gttccaaaag ccgatcacgc
    18781 tcatagactt cgatctttcc aacaaagaaa aaccattcat tgttgatctg ggaaatttgg
    18841 tagcctactg ccttttcttc tttgattttc aaacgacgag gacgataatg ccataacatc
    18901 gtttcccgaa tgtaagtatc taaaacagcg gttggtaact ttttgctccg tgtcaaatca
    18961 tactgataaa atatttcttc gtctactatc gaaaaagaaa caaaaaagct gtaaaacatc
    19021 attgtttcgt atacattcag ttctgctgct gttcgactaa gatgcatcac gatgattgga
    19081 tcgattgctt gataaagccg gtccgactga tagagtaatt tcttttcttt caaagttgcg
    19141 tacgtacttt tttcattcaa tagtcttttt ttcgtaatcc cgagccagca agcaatctgt
    19201 gcttctgctg atgccgtaaa cgttgtttct aatacacggt ccaatcctag aatgaacggt
    19261 cttttttctg gtgtattttg caaaaaaagc ggtcgctgat cttccgggat atattggaat
    19321 agttcataat aaaaatatcg tatctgtagc tcttctccgt ataattgacc gtttttgatt
    19381 tgtaatccaa attcctctaa gagctggttc aattctttga tctttcgaaa aacagaagac
    19441 tcactgatat taaacgctgt cgctaatcga acgatggata cttgctgatg ttctaataaa
    19501 tagacgagca tcttaaactt caagctttcc tgcaataaaa acaatagaat tttttccaaa
    19561 cttacatctt cgtccaacac aagcagcgcc tgatactcat ttcgctgtac ttctactttt
    19621 ttttccatca ttcggccaat caattcaata tcttccaaat attgatcaaa cgaggctttt
    19681 gacagttgga catgctctct caaaccattg atagaggctg ttcccccttg cagaacaagg
    19741 tttcgcaaaa tcaggatctg taactgctct tttctttcta ataatgcttc aatcttcata
    19801 ggcagtattc gccacctttg accacaccat atctggcaca cggtattctg gctggaaaaa
    19861 tagctcatgt tcttctaact gttcaaacgt ccatccttct tctactgcaa ttgtcagttg
    19921 gtcaagaagg tggaacatct cttttttgct ttggagctgt gctccaagaa tctttttttc
    19981 agaatcaaat agaaatttga gtttaacttt gctttgattt attgctgtaa gcttgtagtc
    20041 tacgtatcct gtttcaattt tttggggata aaaaatgctc tcttcttctg tcaaacctac
    20101 gcttcctaag aaatagccaa accactgatt gccgactgga cgataggttc cctgatcctt
    20161 tgtctgtgag ccactaattg tcttgctgac atttcgtgct gtacggacag cgttatttac
    20221 tagagaaaca tacatttttt catttgttgg acgaaaagtt acttggatcg catcgccaat
    20281 cgcataaacg tctttttgag acgtttgcaa gtagtcatct acccagatcg ttccatcatc
    20341 attcaatgtt aattgttctt cccacatctg attgtcggga cgagaatgat tagccagcaa
    20401 aacaagatca tagttctcct ttcttttttc cgtctctaca atagcggttt cattttcggt
    20461 caaagacaca acttgttctt ctaaaaaaag tgaaagccct tgatttttca tttcctttac
    20521 taacggttct gtcatttcag gatctagata acgaaaaaga attgactttc ggctttcgta
    20581 aagatggatt tgtttttttc ttgatgccaa cccttcagct atttcgattc ctgcttgtcc
    20641 tgcaccaata attgcaattt tctttgcatt catgatcttt tgctgaagag ccgttacgtt
    20701 ttgtatcttt ttaactgggt gaataagcgt tgattctgca gaaatatttc gaaacttttg
    20761 atttgaacca gtcgctagaa tcaaacgatc aaaatccaat ttttttcctc ctgctaaaac
    20821 gacttttttt tctttcaatc ctattactgt cttttctgtg taaacatgga ttcgatagcg
    20881 gtcagtcagt tcttctttcg tgatccaaga aagttgtttt tcactggtaa cctttccttt
    20941 taatatcaaa ttgaacccgc tgggaatcca tcctaacttc gattgctttt caatcaaata
    21001 tatttcactt gttggcatca attggcgaag ataaatagcc gcatgaatcc ctgcaaacga
    21061 cccgccgaca attacaatgt tcatctgcat tcctctttct tataaggtgt tctactgcta
    21121 acttctcaat cagaaaacac agtattcata actcgctttc aaccttatga tacatagcga
    21181 tgcagcagaa tcaaccctct ccatcatacc gtgttctagg tctgcttctc aataatgtac
    21241 tagtggacct aattgaagag tatcatttct gaagagatgt ttcaaaaaat gtactcttat
    21301 aaaagaaaaa aactcgcctt ttacgtacct ctgtccaaat aggaaacaga aaagaacgaa
    21361 aagacgagtt ttagcgtgtg taatgtaata gttagaatag acacatcatt tatttttaat
    21421 tctttaatgc ttcaacaact gcttcgccta attgatgagc agattgagga ttttgccctg
    21481 taagaagccg cccatcaatt tgaaccactt ctgaaaaagc tgctccagac tgatagtttg
    21541 ctcctttttc tttcaaagca tcttctgcta agaatggtac ttcattcgtt gtaccatttg
    21601 cttcctcttc ttcattactg aacccagtca ctgtacgtcc agctaaaata gattttccag
    21661 actcatctgt aactggcaac aatcctacaa caccgtgaca aacagctgag accagccctt
    21721 catttcgata gatttgtgaa gcgactttcc caagatctat tgcttctgga aaatcccaca
    21781 ttgttccgtg gccaccagca taataaaccg ctgcataatc atttgcatcc acatcatcag
    21841 gacgtaaggt atttcccaag gcccgatttc tgaaatcttc atcttcataa taggcccaat
    21901 cgatttcatc catattcaaa acactttgcg gttctaaagg tacatatccg cctttaggac
    21961 tgacaaaatc tgcatcgatc ccatttttta ctaatacatc ataaaaatga gtcagttcac
    22021 ttaaccacaa acctgtagga cgctcgatct tttcgtactt ttctacattt gttaatacga
    22081 tcaatacttt cattttccca tcctctttct ataaaaattg cgttattgat aacgtgcttt
    22141 caagaaatta tataatgggc ttggcaaata aagctcttta tatgcttttt caaaaggttt
    22201 cgttacaaat tcatcctcac ggttttccaa taatttctct gcccagtcag gatcgacgat
    22261 catttgctgt ccaattgctg caagttctgc atatttcaat acctgctcta catcttcgcg
    22321 attgcggatc ccaccgacac caactaaagg gatctttcct tgaatcgtgt tatggaccac
    22381 ttcaagaatc gatttatcgt tgtatttatc agaacgagct attcgatcat acatatttaa
    22441 tgaaacatgc agataatcta gttttgactc acgtaatcgt tcaagaagcc agatcgtgtc
    22501 ttcaaaacgg atacctggtg tttcatattc ttctggtgag aaacgatacc ctacgatgaa
    22561 tggtttttta gcatattgtt caaccgctga gaaaaccgtt gttaataatt cttcaataaa
    22621 acgataacga ttttccaagc taccgcccca ttgatcctct cgtctattcg aatgcggaga
    22681 gaaaaattgt tggatcaaat acgtatttgc tccatgcaac tcgattccat caaatcctga
    22741 ttcaatcgct ctacgtgtgg ctttgccaaa tgcttggatt gtttcaacga tttcttcttc
    22801 actcattgct cgtggtgttt ccgcatcagg acgttttgct gcaactgcac ttgcagatac
    22861 aggctgttct ccagataaag ttgctcgact tgtcattcgt ccaccgtgga aaatctgaat
    22921 aatcgctttt gcgccttctc cttggattgc tttcgctagc tcacttaatc gaggaatcat
    22981 ttcatcatga gcgatgctga gttcacctgg ccagcctttt ccgatatctt ggacatttgc
    23041 agcaccagta ataacagcac caagaccttt agaacgttgt ttataataag tgatctcatc
    23101 ttcggtgatc actccattga aaaagctgag ttgtgtcgtc ataggcgaca gcatcaatcg
    23161 gttcttcaat tgaactcctg aaggtaaagt aattgattga tcaaattgtg acattgtcat
    23221 tcctcccata attcgctctg attaacctat cgagaatcat ctatcattaa accactcgat
    23281 tagttgtaca tgcaactaat ttgcttaaaa aattttattt tttttgtaac ttatctgttg
    23341 catcattcat tgtctgggct aattctttac ttgcttcatt tcccaaaact gctttgtatg
    23401 actgatgaag ttcttcccag ctaccatcga cttccttagc aaattggcgt ccttgttctg
    23461 taagataaac taatgacaag cgaccttcgc taactgtttt gacgtatcct ttatattcta
    23521 atttttcaac aaaacgagca atcgttgatg gggcggaata gagcatttgt gcaatatctt
    23581 tttgtggtat tccatctttt tcttttaata tcaataaaat aaaaccataa gttggtgcca
    23641 gacctgtcct tctaaacgct tcatcagcta atttattcaa catgcgatct agctttttca
    23701 cgctaaagaa aagacattca tctaacgctt tttcaattgg cttttccatt tcatcccctc
    23761 cattggcgta catatcatag tatgattttt attttttgtc aaaaaacacg gaataatgtc
    23821 cgcctcctct gtctagattt gaaaaaaaga agtagccatc ttcaaagaat ttcggcttgt
    23881 tttcgacaaa actccttctg gaacaccgtg aatcagaggt tgtgaaaaag tcgtttagtt
    23941 ttgagtatga agaaaaattt tgtgaaaatg gctttccaca tttttgcata aatttggctt
    24001 aataccgaaa aactggcttt tgaacaccgt ttatatcaga ggttgtgaaa aagccgtcct
    24061 gcatcaagta ataagaacag ccaaacaaaa atagttcctc atattttgtc gttttttgag
    24121 ctaatgccga tggtcagctg attgtacacc gtttattgag aggtcgtgag cctgccgttg
    24181 aactccgagt cacaaggagc aatttcaaaa aacagcttct catgttttat gactatggtg
    24241 acttgtgatc gaggagttgg caggagaata ctgtttattc gtaaagaagg ggctgtgaca
    24301 agacttttgt cacagtccct tatttccttt tattatagga tttcgccatt tgattggatg
    24361 acttgtctgt accaatcaaa tgattttttc tttaaccgtt tctttgtgcc attcccttcg
    24421 tcatcttgat caacatagat atatccataa cgttttgaca tttgtgaagt agaagcgctg
    24481 acgatatcaa tgcagcccca cgacgtataa ccaaataaat ctactccatc tttgatagct
    24541 tccttcatct gctcaatatg ctgcttcaaa tagtcaatgc ggtaatcgtc ttgaacggtt
    24601 ccatcttctt ctactttgtc tatagctccg agtccgtttt cagctatgaa cagtggtttt
    24661 tgatacctat catataattg attcaaagca attctcaaac ccttaggatc aatctgccag
    24721 ccccattcac ttgatggaag atacggattt ttaattcctc cagttattaa gtttccttgg
    24781 accccttccc aattttctgg atgagcactg actgcactag acatgtagta gctaaaagaa
    24841 acaaaatcaa cagggtaggc tgctaagatt tcttcatcac ctacttctat ttttaagttg
    24901 acaccttttt cttcaaacat tcgttgcgta tacgctggat aatatcctct tgcttgaaca
    24961 tcactaaaga acaaagaagt tctttgctgc tcaattgttt tttgaatatc atccggatca
    25021 caagaatacg gaacaagaag ctgatagctg atcatacaac cgacttgtga acctttgata
    25081 atttcatgac aagcttttgt agctaaagca cttgctataa actgatggtg tgcaccttgg
    25141 tatttcgctt gttccaaatg gggatggttt tcttcaatta ctcctacgct aacaaaaggg
    25201 tgatgtttta cacagttgat ctcattgaaa gtcatccaat attttacttt atttttatag
    25261 cgtttgaata ctgtttcagc gaaacgaacg taaaactgaa taagctttcg attaggccat
    25321 ccaccatatt ctgtaaccaa atataacggc atttcataat gggaaagaga aacgactggc
    25381 tcaatcccat attttagaca ttcgtcaaac acttgatcat aaaaaaataa tcccgcttca
    25441 ttgggtgttt cttcatcacc atgaggaaaa attcttgtcc atgcgataga catccgatag
    25501 catttaaaac ccatttcagc aaataaacgg atgtcttctt taaagtgatg atagaaatca
    25561 tttccgtgtc ttttaggata ataatacttg ctgttgggat cctgcgccgc ttttacttgc
    25621 tgatgcgtca tcatatgcca ttgatctgtc catttttctt taggtaaatc gctgtcgaat
    25681 gtatacacat cagacacaga taatcctttt tcatctacat cccatgcacc ttcacattga
    25741 ttggccgctg tcgctccgcc ccataaaaat ccttctggaa attttttcat atcgatcccc
    25801 ctaaacttgc tagttttctt gtttgattat ttttcttatg actagtaatg atatttttga
    25861 atctactact atttgtaaca ataaccattg tggtcggatc atatccctct ttgattaatt
    25921 cttgcaaatc tacttccatc aataaatcgc ctttacgtac tttttttcca tcagatactg
    25981 cactttgaaa gtatttgcca tttaaattca ctgtatcaat accgatatgg atcagtatct
    26041 ctgctccttc ttcactgact accccaattg catgtttcgt tggaaaaact gttgaaactt
    26101 ccccgtttac agaactgtag atttttccgt ccgttggaat gatcgcaaac ccttctccta
    26161 aagatccact agcaaatgtt ggatcgttta cttcagataa atcaattatt tcacctgctg
    26221 caggagtact taacactata tcctttgagg attcttcttc gatttcatcc ttgtagccga
    26281 aaagaaaagt tagcatacag gaactgatca tcgctaagaa ataactagca actagccaaa
    26341 caaatccttc accaatataa atcgggaaag acaaaatact tcttgtagca actgccaaag
    26401 caccggctcc tgcggcacca gctactccac caaatatagc tccacatata caagcaatgt
    26461 aaaatggtcg tttatattta agagtcacac cataaacagc aggttcagtg attccaaata
    26521 atgctgtgat aaatgcagat aaagataaac tttttacttt cttatttttc gttttcaaaa
    26581 ataccccaag tactgctcct gcttgcgcag ctacggcagt catacatgct ggacctagcg
    26641 tatcacgacc gtagaaagaa agattgttgg tcattactgg tacaagtccc caatgtaacc
    26701 caaaaatcac taacacttgc caaaatccgc cgataacagc accagataaa acagggctaa
    26761 agttataaac agctaaatat ccagctgcaa tcagctgact tgcataatct gcaattggac
    26821 ctacaactaa taaaataatt gggaccatca cgatgataca aatgaatggt gtcaataaat
    26881 ttcgaatact ttcgtgcaag cttttgcgaa tcttaggctc aatataagaa agaacccata
    26941 cagctaaaat tgctggaata accgtacttg tataccttgc tagaatcacg ggcatcccta
    27001 gaaatcgcaa ggttatgcta tcactatatg cactgacaat cgtaggataa acgagagctg
    27061 ctgcaataac catagcgatg aaacgatctg tattgaactt ttttgcagca gtatatgcca
    27121 aaaatatagg caagaaatag aaaaatgcat cagctgctgc attcaaaatg atataagttc
    27181 ctgattcagt agttaataaa ttcaaactcg tacataaggc gagtactcct ttgatcaaac
    27241 cacttcctgc caagacgcct aaagtcgggg caaaaacagc ggcgatcatg tctataaaag
    27301 agtttaaaat gccttttttc tcagttcctc tctttccact agatgcatca tcttctagtt
    27361 tcatttgttt ggataatacg tcatacactt catttactgc atttcctact acgacttgaa
    27421 acattcctcc agcttcgact acagtgatca caccttctag ttgctctacc ttctccttat
    27481 ctgccttctt attatctttt agggtaaagc gtaaccttgt tgcacaatgg taaacattgc
    27541 tgacattttc ttcgcctccg acaaatcgga caatatcttt cgctaattgt gaatagtcca
    27601 tttttacttc ccccttgtta attaatgccg tagcaatcct tcttacaaga taagtatagt
    27661 tcttagaaaa cggtttctcc attcaattag taccccttct aatagcgaac gaaactgtac
    27721 aatagtgtgt atggtttact tagccgagca aatcactcac tgcttgaaag aaaacaagta
    27781 tatcgtttct cttatagtca aaggagacaa aaaaaacacg cttgatcttc ctttgctgat
    27841 gtataagtgg tatctcaagc tgatactctg tgatttttgt ttctacttgg cttttgataa
    27901 gacagcacaa caaagtctcg gcatttaacg gaagcataac taggtcagaa ctaggagaga
    27961 ttagttgctg aatggaatct atctttttat ggatttttat ttgattttct tctttgtagt
    28021 aatgatcaag cagttttgtt ttcttttttt cttcaactat ggtcagcttt tcacgcaaaa
    28081 tctgataaat ctcccaagat tcaaactcat ctagaacact aggtagataa atcaaatcat
    28141 cccactcaaa aataagctct tgctcagtag tcaaaattgc atcatattcc gttattttgt
    28201 ttgattgatt tttgaaaaga tacactggtt ctatccggca ttctttgatc cacatgttca
    28261 tactttgttg aatctgtttt tttagtgtat tcaaaatact aattggctgg ttactaacaa
    28321 tcagtatctc cccttgtttt cgaaaaggat tcaacgcttc ggcaagatac aaaacaaaat
    28381 aagcgctttc agctaaattg ggacgtaatt gaaaatgtat tgggaagaaa cgccgaatta
    28441 aataaatttc taaaggataa cgggagatga tcttttgtac aaaatgattc atggtattat
    28501 gtccggcatc catcctcgtt ttcatttgtt tgatatgggt tagcaaaaat tctgtttcat
    28561 ggaacaataa cgaaacagga agatctaaaa aacgaataat cgtttgctca aatgctctta
    28621 gattcttctc tatttctttg tttttttcat cattaatcat caaataattt aactctaata
    28681 gtcgattttc aattgcttgt ttttcttgat tggaaaaaga atagggtagt tctgatgata
    28741 acttttttgt gagggtctct accatcggaa taaataatgt atacctgttt gttttttcta
    28801 aaagttcttc tcttcgaaga atggtcaaaa cgagataccg agaaaatcgt atgaagtcct
    28861 ctcctgaaac aatataatta tatgatataa gaacctcttt taatgtcttt tggacagtcg
    28921 gcatgatatt ggaaaaaatt gtactgattt gttgaggaaa ccttgcgtgt tggatcaccg
    28981 tttctgttcc aacaagagat aagaaaattc tttttgaatt ttcttcagca atgattttta
    29041 gtccttttgt cgacgaaact tccagttcta atttaggatt gcgctcgatc caacgcaaaa
    29101 tcgtttttat ttgtaatgat acggctgttt ttgaaagaaa gaaaatgtct gctatctttt
    29161 gcatactgac ataccctttt tgaaacaata agtacgtcac aatagttgaa gctcggaaat
    29221 ccatgctgga atagatttta tgtttcgtca cctcttgtat gatttgctgt ttagtttcag
    29281 attcaattga ttctaaaaaa taacctgaac gtttatttga ctggataatg attttcttct
    29341 cgtagatagc aagcatattt ttgatttcag tttggatcgt tttcttgttg gtacctaaag
    29401 cttcagctaa ttcttcgctt gttatccaat gattcttatt tcttaatact acaagaattt
    29461 ggagttgtcg tttatttaag tccatttgct tacacctcct ctttgttata aacatacagg
    29521 aaaaacctct caaatgacaa tagtcacttg cagaggttta aaaatcattt gaagaaagat
    29581 ctatattcaa ggtttttacc attagactgg ataatttgtt tataatattc aaaactatct
    29641 tttttcaatc tcctaaagct tccgctccca tcattttgtc tatccacata aataaagcca
    29701 tatcgcttcc tcatttcccc tgttcctgcc gatacgatat cgattggtcc ccaccataag
    29761 taaccaatga tttggcaacc atcttttatt gcctcagcaa tttcctgaag atgtattttt
    29821 agatactcac aacgttttgg atcgtggatt cgattcaatt catctggtgc ttcatctagt
    29881 ccaatgccat tttcaactat gaataatggt aattcataac ggtctgtcaa ttcattcatg
    29941 acataacgaa accctagagg atcaattggc caactccaag gttcgggaga tttttccttc
    30001 aaaaagggat tatcgaaacc atttgctccg ccagtatcta cgcgcatttc tgcttctttt
    30061 ttatagacag cgctacgata ataactaaat gcaatataat ctgccgtgtt agcttgcaag
    30121 cactgttcgt ctccatctaa cattactggt gcacagtctt cttccttcca tgtcctgtaa
    30181 atataagctg gataatgccc tcggcacatg acatcggaga aaaaccatga attgcgttta
    30241 aattgcagtg aaccaaatac attctctgga tcacagtcat atgcataagt cgctaatgca
    30301 gaaaagctac acataatacc catcttagca tttggatcga ttttctttaa taattgagta
    30361 gcacgggcgt tcgctagaaa catatgatga caggcttgat aaatcacttt ttttgttagt
    30421 gtagcaatgg gttcaagttt atctctagca gggaatgtaa ccaatccagc agctgcataa
    30481 ggcatacgaa aagcattatt gatctcatta aaggtcatcc aatatttcac tttcccttgg
    30541 tagcgttcaa agacggtctg cgcataaaat tcaaaaaagt cgattaattt tcgattttgc
    30601 caccccccat actctcctac caatgctaag ggggtttcat aatgactaag agtaattact
    30661 ggctcgatat catatcgatt taatgtattg attagtctgt cataaaatac gagaccagcc
    30721 tcatttggct tctgttcgtc tcctcttgga aatattcgtg cccatgagat gcttgttcga
    30781 aaagctttta aacctaactc cttcagtaaa cgaatatcct cttcaaatcg atgataaaaa
    30841 tcaatcgctt catgagaaag ataatggagt gattcgtcta aagcaatctc ccaaatcttt
    30901 ttttcttcat tccactgaat actaggatgc tggttcatga tcccgataag cgtatctgtc
    30961 acattaggta atttgccgtc ttccaaccat gcaccttcac attgattagc agctactgct
    31021 ccgccccata aaaaattttc tggaaatatt tcctgatcca taactatctc tcctcgctat
    31081 caacaatttc ttacttgaag tatagctcga ttcatcaaaa caagatattc taactatttc
    31141 ggcagaagag aagaaaaaaa ttgaatgcta ctcttcattt ttaatattta tatataacaa
    31201 atacataaga cgatccccga aagaaaacac tcgttaacca tctaagcaaa cgatttattt
    31261 tacttccaac acaaatgctt cataaggtcg taaatcaact ttgccgtctg gtaactgttt
    31321 cagaggataa tttgacacaa taacccttaa agcttcacgt ggaatagtga acgtctgctt
    31381 ttcactggac atattacaaa taacgagcca ttgctggtct tcatatatgc gagaataggc
    31441 aaagacatgc tcaggcgtct tttccactaa ttcatagtct ccccagacga tgatgtcatg
    31501 ttttctacgc aaatcgatca atttcttgta catataaaaa acagaatctt gatctgctaa
    31561 cgcttcttct gcattgattt ctttataatt tggattgact cgaagccatg gaattccagt
    31621 agtaaaccca gcatgttcac gggcgttcca ttgcataggc gtcctagcat tgtctcttcc
    31681 tttcgccttg attgattcca agatttcctc ttttgtaaat ccagaagaaa tcctttcgtt
    31741 atacatattg attgtctcaa tatcttttgc ttccgcgata tcatcgattg ggcaattcgt
    31801 catgcctaac tcttctcctt gatagatata aggggtgcct ttcatcatat ggagcaagat
    31861 agcaaacatc ttggcacttt cttttcgata cacatcgtca tttccccaac gagaaacaat
    31921 tcgcggaaga tcgtgattat tccaaaataa actattccat ccttcatcac ctaaagatgt
    31981 ttgccatttg gataatactt ttttcagttc agagatactc aagggtttca aatcccattt
    32041 gtctttgcct tcttgctgat ctaatcctat gtgttcgaat tggaagacca tggataattc
    32101 atttctttta ggattggaat aaagtttagc gatttcggta gttgctcccc atgtttcgcc
    32161 aacagtcatc agatttttgt caccaaaagt tgcttgattc atttcctgaa gatactcatg
    32221 cagtttaggt ccattacttg tgatttcttt atccggttct ttgccaatca tatcgatcac
    32281 gtccatacga aagcccccaa tacctttatc gatccagaaa ttcatcattt gataaatctc
    32341 ttggcgaacc tgtttatttt tccaattcaa atcaggttga cgcttgctat acaagtgcag
    32401 aaaatattgc cccgtttttt catccaactg ccaagcagaa ccactgaata ttgagcgcaa
    32461 tctattaggc tcttttccat tgaccggatc acgccaaata taatagtccc gataaggatt
    32521 ttctttattt ttacgggcct caatgaacca cggatgttca tcagaagtat gattcaccac
    32581 cagatccatg atgatacgga tatttctttt ctttgcttct tcaatcagtt cttccatttc
    32641 ttccatcgta ccgaattctg ccatgattgc ttgataatta ctgatatcat acccattgtc
    32701 atcattcgga gactcgtata ctggagaaag ccaaattgca tcaataccta aatacgccag
    32761 ataatccaac ctggaaataa tcccccgcaa atctccaata ccatcttgat ttgaatcttg
    32821 aaaacttctt ggatagattt gataaacaac tgaatggtgc caccattttt gttccatgat
    32881 tttcctccta taaatggatg tttctatttt ttgcttaatc atttatttta gtctctctca
    32941 ctaaaaattg taacgctttc aaatagctat tgcaccttgt tatcggtaac agaataaaac
    33001 aaaaaaacag ctgaggaaat tccctcaact gttttttgaa aggattgatt tatgcaggga
    33061 agaatgctga tttcacaact tctttataaa cggtgttcac tcagctgtcc cttggtatta
    33121 gctcaaaaaa cggcaaaata taagaaacta ttttttcgtt tttttctcta atactcaggc
    33181 cagaacgctg atttcacaac ctctttattt cacattcaat atccacatga atcccacaaa
    33241 tacaaagaac agaccataca tgattggaga tacttctttt cctcttttag ctgctaacat
    33301 ggtaattgga tagaagataa aacctaatgc aatcccatct gaaatactat aagtcaaagg
    33361 catgccgatc aagatcaaga atgaagggat cgcaatctct aagtttcccc attcgatttg
    33421 tcgcaaagat tgtgccatca atactcctac cataatcaat gctggtgcag ttacttgtga
    33481 agtaacaact gatagtaatg gagaaaagaa caagcctaac aagaagaaaa tccctgtagt
    33541 aatagctgtg atacctgaac gtcctccaac ggcgatacca gctgatgatt ctacaaatgc
    33601 accaacagga gaagtaccaa ataaggaacc cgcaagcata gctgttgaat cagaagctaa
    33661 agctttccct acacgaggca tcttgttgtc tttcatgaaa cctgcttggt ttgctaatcc
    33721 aactaaagtt cctgctgtat caaagaaagt cacaagcaag aatgtcagca ctacgaccca
    33781 catttgaaga gaattgatgt cccctacatg ttttaatgca actaaaaatg ttggtttcaa
    33841 acttggtgct gcggcaacaa tttcagaagg cattggaatc aaacctgtga ccagacctaa
    33901 aatcgttgta gctgccatcc cgatgaagat gccacctggt acacgccgaa caagcaagat
    33961 agcagttacg actaatccaa aaatcgtcaa ccaagtagaa ccaacgttga gtgatcctaa
    34021 tcctactaat gtagattcat tcgaaacgat gatcccacct tcgctcagac caaggaaagc
    34081 gataaataga ccgataccgc cagaaatcgc atatttcaaa tctgctggga tcgcatcaat
    34141 gatcatttcc cgcagcttga agattgtgat caaaataaaa atcaaagaag caacgaatac
    34201 gccggctaat gctgtttccc atggaatccc cattcctaaa caaacagaat aagcaaaaaa
    34261 agcattgatc ccaagagcag gtgccgttcc aattggataa cgggctaata cccccattaa
    34321 aacacagccg atcgcactgg ctaatgcagt cgcagtaaac actgctcctt catccattcc
    34381 agaagcacct aatacagttg gatttacaaa taagatataa gccattgaga taaatgttgt
    34441 aaatcctgcc agtacctcac gttttaccgt ggtgttcaat ttttctattt cgaagtagga
    34501 aagtattttt tccttcatct tccatccccc taaatccgaa cattataaat aaagtccgtt
    34561 aaaatttcga tttattaata aaacaacgtg ttttatcata tactaaaaca aaacataagt
    34621 aaacaaaaaa ttcggatttt aagcaaaatc cgaacgttcc atctgattaa atccctttat
    34681 ctcaaagttc atgaacattc actttggatt acaagaattt ctttattgtg ttaataaagt
    34741 ttcttcattc tagtctcaaa aatcaatagt gtgatttgat tttaccattt cgtttctgtt
    34801 cttctttgat gaattctttt gtatcgacag gattcagatt atttagtccg ccaaaacctg
    34861 tatcgaccat ttttccccag ccttttgtct tcttttttcc tgatttgaga ttctttgctc
    34921 gaagcttctc actatgtttt gctcgccgat acttcaaata accttctaat cttcccatta
    34981 gatccactgt ttttcctcct ttttattcaa tcagacgact cagcttttcc tataacaaaa
    35041 taattgcctt cagggtcaga aaaattgaaa gtcaagatgc cattgttatc tgtgatttct
    35101 cctggttctt ccatgttctc gtagatagtt tcaaattcat ccgtaaaaaa tactaaagaa
    35161 ggcggtggtc ctaatacctc tggtgaaaac ttctgcacaa atacttttgg gaatacgcct
    35221 aattctaatt cttttgagat gctgagtaca atactcttaa attcttctgg caattcgatt
    35281 gtttcagaaa tttctgcacc aattttttct acaaagaatc ggcaaatcat ctctacgtca
    35341 ttgacataaa gcatcacacg tgttttttgt atcatcattt gacccttctt tctatttgat
    35401 tttctttcct gtctataaac tgattccatt atatcacgaa agcgcaaaca ccttgtgttt
    35461 gatactattc aagaaaaata aagcaatagt ttctaggatt gctttcctcc acaaactttt
    35521 tttacaaaaa aaaaacggca atgaatgccg ctcttcttat ttcgattctt ttataattct
    35581 gcttctgatt catctttggt tagtgtgtgt ctaacactag ttacgccaaa tgtttgatcg
    35641 attttttcct tcaacgcttc gattgcctgt gcgccacgtg ccgcttgttc agcattgatg
    35701 gattcaatga ccagcaccgc tgcttgtgtt tcttccgtca gcatcgttct ttgggcttca
    35761 cgccagttga gacagcgaca gatcgctcct tgttcatcat agtagatgat ttcttccgga
    35821 agtgccggag catcggaatc tgcacctaaa ggcaggaatg attcgccacc ttgggctttt
    35881 cctaaatgca gatttcctgc gatcttttcg atatcttctc cgccgcaagg tacgccaaaa
    35941 gacaaggaaa tactattata gatatctaca agcggattga ttgggaaaaa ttcccgttct
    36001 tgatttgcac gtttcagtaa agcttcaata gaagaacgtg cacctttttt agtcttgaat
    36061 gtggtaaatg cctgacgcca ctgagcaatg acttcgtttt ggctgaatgt ttcttctgta
    36121 aggtaatttc ttgcttcttt tgctgcctca ttcaataatt gatgatacgt ttcttcactt
    36181 tcttttgtta cgtggttatc gataccattt acggataaga tttcgatggt tgcttcagga
    36241 aatacttccc agaaattggt atccactatt acttttttca tctgttcaca cctcttgatt
    36301 agaataattg cttgatgaat agatagtctg tttggggatc atctcccata taaaaaacat
    36361 gttcgctgta tttgataaat ccttttttac gataaaaagc gagcgcaaca tcgttgtgtt
    36421 cccaaacacc gagccaaatg gctgtttttt gcttttcttt tgctttttca atagctgtat
    36481 ctagtaaaaa tgtaccgata ccttgatgtt taaatttttt tcgtacatag attcgctcga
    36541 tttctaaaaa atgatcagcc atttcctcag attgactcgt tcctgtattt agtttcaggt
    36601 aacccgcagg ctcttgatcg atactcacta ggaaaaaatc ggtttcttta tcttttagct
    36661 cttctgtaag tttttctagt gcataagctt gtgtcaagta atcagctaaa tgctccggtg
    36721 aattatcttt tccaaatgta tctgtaaatg tttcgatact aatttgttgt agtaagtcta
    36781 catctgaagg cgtcattttt cgaatttcgt atttattcac ggcttcttcc tttcaataga
    36841 tccttttatt gccttttttg acaaaattcc aatcttcgct aacattcttg catactttat
    36901 ttaaaagata ttccaattgt tttgcttctt cgtcagaaag accatttaat gcgactgcat
    36961 tggagtagtt gttttctcga atgatgaaag gatagatttc tgctcctttt ttagtcggat
    37021 agagtttctt gattttttta ttttctttat cttccaaacg ttcgatcatc ccattggatt
    37081 ctaatttctt gattgctcgg gcagtcgttg tacgatctac tttgatcatt tctgctagtt
    37141 tttcttggat gattccagga ttttcgcaaa tacgtactaa ataaagatac tgtcctcttg
    37201 ttaaatcgac ttctttgaat tcgatattgc taatagaatc tagcgctcgg gcaatcattc
    37261 cgatgtctcg aaggatttca gccatttcat cccaccttta ttttgtttgt aagactagtt
    37321 cacctctttt tgttgcaaat gcaactattt tcaataaaaa aatcaagttc ttttttaata
    37381 actagtaaag tatattcttt tcttctttta cgaaaaagct caatcacaat agatctggtt
    37441 tttgttttct aaaataagta actgtttctt cgttgttcgc ttttctgata gctttggcaa
    37501 ctcttctata ctaaaaaatc ccatgttgga agtttcatta ttctcaataa acttggcctc
    37561 ttcaccgtgg atcgcacaag caaaaacaag tttataatac tgaaaaagct gtggaatatc
    37621 tttttgttta ttcgtatcaa aaactgctcg caactgagta gtttctactg ttaatcctgt
    37681 ttcttcatag acttctttac gcacattttc ttcaggagac aatcctattt cagcaaatcc
    37741 accaggaagt gaccattctt tcgtccgttt atcttcgatt agtaggacct tgccatcttt
    37801 tttgatatag gcacgaacat ctacttttgg tgttggatgt ccttctccaa tcgttgtgag
    37861 cgcttttatt tcttcgaaag tttcttttcc tatttcactg atcagttcca atgaaatcgt
    37921 ccggatctcc tcaaaacgct ctttatcaaa tacatctttt ccataatata gaccagcttg
    37981 agaaagtgcg agtagtcttt tgtattgagc caacttcttg ttcattctct tcccttcttt
    38041 tttagcaaat gtatgactat gtaatcaagt atagaagact ggtttaatta cggcaaataa
    38101 atataatgaa atctgcaata aataaaagaa tgttaaaaaa ctcgagaaca aaagacattc
    38161 gacttctctg gggctgtgaa taaatggcgt tcaaaagctt gcatctgcgg taataagccc
    38221 caccaaacga aaaatatgac gagctattct tgtctggctg ttcttattaa ttgaggcagg
    38281 acagcttttt cacaacctcc ccactaaacg gtgttctcct accaactcct cggtcacaag
    38341 tcacaatatt catcaaacat gagaagctgt ttttttgaaa ttgctccttg tgactcggag
    38401 ctgaacgaca ggctcacgac ctctcggtaa acagcgttca aaagccaatt tttcgatatt
    38461 aagccatttc tttgttactt attgtcattg atttcttttt ctaatttatc caatagtgga
    38521 gtgtaatcca cttgagtata gtctgttaca tcaaattcat atagtgttcc taactggaat
    38581 ttgtcatatt ttcggtcggc gatgatcttt ttgaatgctt ctttcgtaat atgattggtc
    38641 cctttcgttc gatcttccaa tacgtcacca tagtgataat gatccatgat atagctcaaa
    38701 tgacgatctg attcacgatc acgtttgtac cgacgttgcc ataacacttc aaagtctgct
    38761 gttaggcgaa tcgtgatcac ctgatatccg tatctatctg ctaattcttg gagtcgtgct
    38821 ttttgcttat cactaaaagg atactcggac acaatcactt tctttcctgc ttccatatac
    38881 aaatcaagtg ctttgtaata gaaaggataa actttcgtcc tttcttgttc cgcccgttct
    38941 tccaaattgt taaacccgat ggattctgca tagtattcct tgatttcatc gagcgtgatg
    39001 gcatacatat ctggaaatcg ttcccgtagt ttattcataa gatatgtttt tcctgtacca
    39061 ggactaccag ccagaagaat gaaatacttt ttcatctcat ttatttccta agttaattgg
    39121 actttccaag ttcataaaca gtccaatctt atgcttgaca atttctttta ctgcttcatt
    39181 tgctggaatc acattatggc gaagagactt gttgatttct gtttcactaa aggtttcttt
    39241 agctactttc gtccagttga ctaaaagctc cgttccaaca ttgaatttgc ggatcccgtt
    39301 attgatcaat tcaggataat cttcttcttt cacacctgtt cctccatgga taactagggg
    39361 gacatcaact actgcatcga tttctttcag caagggaatg tttacttctg tttttgattt
    39421 gaattgtcca tgattcgtac cgatagcaat agctaatgca tccacgcctg tagcttctac
    39481 aaatttcact gcgtcttccg gtcttgtata taccttgtca ttttcagcga catggattcc
    39541 ttcttctgta ccgccgattg ttccaagttc tccttctacg gaaacaccgt gcgcatgggc
    39601 atattctact actgcttttg tcttcaggat attttctttg aaaggcagat gggacccatc
    39661 atacatgaca gaagtatatc cgctgtcgat tgcttctttg atatcatcaa agtctcgggc
    39721 gtggtctaag tgcaagactg catcaaccat ttcttcttct gcaatagctg tcattacatt
    39781 gactaacaca tgcatgccga tatatttagc ggtatcgaca cttgtttgaa taatgatcgg
    39841 cgaacccatt tcttttgctg cgcctagcat agcaggaagc atttctaggt tatgcgtatt
    39901 aaaagctcca actgtaaaat tcaactcttc tgctgttttt gttacttctt tcaatgttgt
    39961 atacatcttt tattgccacc ttatcttttt atttgtttcc tttgatcgtt acttgttttg
    40021 caatttgtcg catctcatcc attttgccca tgtagtaatc gatcccttga tcatcaccag
    40081 cacgagcagc atctgcacgc ttctggttat agaggctcat cagtttttta tacccatctc
    40141 cgatcgtctg tttattttcc aaactctttt ctaaatattg gatggcttga tcgttcacat
    40201 acaattcaga aaatttaagt ccaacttgtt cataaagttt cgctaattta tgcttatctt
    40261 gggtagtgga aatctcttgt ttcaattgtg taatctctga ttgaatcttt tcggtcgctt
    40321 ctggcgatag ggctttttct tcttttgcca gaactttttt cggttctttt tcttttttct
    40381 taaaaaatcc aaacatcatt ttccctactt tcaattaaaa tgctttcaaa actgggctta
    40441 agatccaggc atataagagt gctgcggcta ctgtatctac atcggttgct gtagcattgt
    40501 tgaatcccat cgaattaaag atcgttacta gcaaagcggg caataatgta ataaagaaac
    40561 catgagcaat accgccaatg atcgctcctc ggcgtccgcc aactgcgttg ccaaatatcc
    40621 ctgctgtccc tccggcaaag aaattggtta gcataccagg taaaatcatc gctaagccga
    40681 acatgggcaa agtaaacatg gcaataatcg taccaatcgt tgtcgtaatg aaacctaaaa
    40741 tgacagcatt tgggctataa ggaaagaaaa ctggacaatc taaggcaggg atcgcatcag
    40801 gaactaattt catagctatc cctcgaaatg ccggcacgat ttcacctaac agtagacgta
    40861 caccagctag caatacatac acacccacta cgaattggat ggcttgtaaa aaggcaaaca
    40921 tgatatagtt ttgatctcct gataattcag aagcgaatgg ttcgcctgca aataaaacag
    40981 tgatgatata tagcgggacc atcacgacca tgacagacaa ataagtatct tgcagaaatt
    41041 cgaaatgtgt cggcaacttg atatcttcga tcgacttttt attttcgcct ttctcaccaa
    41101 aaagcttagc aacaccggct tcaaataagt acccgatcgt acaaaaatga cctaaagcaa
    41161 tatcatttga tccagtgatt ttacgaatga tcggttgcgc tactgccggc atagcaatgg
    41221 cgaaacaagc tccgataaaa ccaccgacca agatcaatac gatccctcgc agaccggcaa
    41281 aatagccaaa gactgtcgtc atcgttgcca tccataaaat tgcttgacca gttaaaaaaa
    41341 tgtacttcca ttttgtgaaa cgagccaaaa taatattgaa tacaaaaatg gctaagaacg
    41401 tcagtgcaat atctctacct aaacccaaat cattcattgc ttgaccattg atagattcaa
    41461 tagaagggat gatcccttgc atatgaaatc cttcagtaaa gattttcccg aaataagtta
    41521 aacttccaac gatgatgctc gaaccggcac tcaacacttg aaatcctagg agtgtcttta
    41581 acgtgccaga gatgacttgt cctgctgatt tcttctgcag tagtagaccc aacatagcaa
    41641 tcaatgcaat ggtgatcgat gcctgagtca aaatattttc gatgataaaa ttgataacgc
    41701 ccatgtt
//
LOCUS       DAFLVO010000019        39930 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.019, whole genome shotgun sequence.
ACCESSION   DAFLVO010000019 DAFLVO010000000
VERSION     DAFLVO010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39930
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.019"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            165..1034
                     /locus_tag="L1U99_001040"
     CDS             165..1034
                     /locus_tag="L1U99_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HBN1211596.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            1199..2470
                     /locus_tag="L1U99_001041"
     CDS             1199..2470
                     /locus_tag="L1U99_001041"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBN1211597.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            2467..3762
                     /gene="rho"
                     /locus_tag="L1U99_001042"
     CDS             2467..3762
                     /gene="rho"
                     /locus_tag="L1U99_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBN1211598.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            3861..4124
                     /locus_tag="L1U99_001043"
     CDS             3861..4124
                     /locus_tag="L1U99_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HBN1211599.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            4569..5018
                     /locus_tag="L1U99_001044"
     CDS             4569..5018
                     /locus_tag="L1U99_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1211600.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            5075..6493
                     /locus_tag="L1U99_001045"
     CDS             5075..6493
                     /locus_tag="L1U99_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1211601.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            6493..7353
                     /locus_tag="L1U99_001046"
     CDS             6493..7353
                     /locus_tag="L1U99_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBN1211602.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            7527..8300
                     /locus_tag="L1U99_001047"
     CDS             7527..8300
                     /locus_tag="L1U99_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBN1211603.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            8447..8812
                     /locus_tag="L1U99_001048"
     CDS             8447..8812
                     /locus_tag="L1U99_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HBN1211604.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(8960..10168)
                     /locus_tag="L1U99_001049"
     CDS             complement(8960..10168)
                     /locus_tag="L1U99_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1211605.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(10187..10465)
                     /locus_tag="L1U99_001050"
     CDS             complement(10187..10465)
                     /locus_tag="L1U99_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211606.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            10619..11314
                     /locus_tag="L1U99_001051"
     CDS             10619..11314
                     /locus_tag="L1U99_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBN1211607.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(11756..12553)
                     /locus_tag="L1U99_001052"
     CDS             complement(11756..12553)
                     /locus_tag="L1U99_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HBN1211608.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(12550..13734)
                     /locus_tag="L1U99_001053"
     CDS             complement(12550..13734)
                     /locus_tag="L1U99_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBN1211609.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(13759..15006)
                     /locus_tag="L1U99_001054"
     CDS             complement(13759..15006)
                     /locus_tag="L1U99_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBN1211610.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            15221..16966
                     /gene="dnaX"
                     /locus_tag="L1U99_001055"
     CDS             15221..16966
                     /gene="dnaX"
                     /locus_tag="L1U99_001055"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBN1211611.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            16986..17300
                     /locus_tag="L1U99_001056"
     CDS             16986..17300
                     /locus_tag="L1U99_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBN1211612.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            17325..17921
                     /gene="recR"
                     /locus_tag="L1U99_001057"
     CDS             17325..17921
                     /gene="recR"
                     /locus_tag="L1U99_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBN1211613.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            17985..18629
                     /locus_tag="L1U99_001058"
     CDS             17985..18629
                     /locus_tag="L1U99_001058"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HBN1211614.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            18644..18973
                     /locus_tag="L1U99_001059"
     CDS             18644..18973
                     /locus_tag="L1U99_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HBN1211615.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            18987..19925
                     /gene="holB"
                     /locus_tag="L1U99_001060"
     CDS             18987..19925
                     /gene="holB"
                     /locus_tag="L1U99_001060"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBN1211616.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            19961..20785
                     /locus_tag="L1U99_001061"
     CDS             19961..20785
                     /locus_tag="L1U99_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBN1211617.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            20778..21125
                     /locus_tag="L1U99_001062"
     CDS             20778..21125
                     /locus_tag="L1U99_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HBN1211618.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            21194..22066
                     /gene="rsmI"
                     /locus_tag="L1U99_001063"
     CDS             21194..22066
                     /gene="rsmI"
                     /locus_tag="L1U99_001063"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBN1211619.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            22175..23296
                     /gene="dinB"
                     /locus_tag="L1U99_001064"
     CDS             22175..23296
                     /gene="dinB"
                     /locus_tag="L1U99_001064"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBN1211620.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(23350..23952)
                     /gene="nrdG"
                     /locus_tag="L1U99_001065"
     CDS             complement(23350..23952)
                     /gene="nrdG"
                     /locus_tag="L1U99_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBN1211621.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(24267..26456)
                     /gene="nrdD"
                     /locus_tag="L1U99_001066"
     CDS             complement(24267..26456)
                     /gene="nrdD"
                     /locus_tag="L1U99_001066"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HBN1211622.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            26755..27549
                     /locus_tag="L1U99_001067"
     CDS             26755..27549
                     /locus_tag="L1U99_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1211623.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            27539..29581
                     /locus_tag="L1U99_001068"
     CDS             27539..29581
                     /locus_tag="L1U99_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1211624.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            29862..30011
                     /locus_tag="L1U99_001069"
     CDS             29862..30011
                     /locus_tag="L1U99_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HBN1211625.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            30022..31536
                     /gene="dltA"
                     /locus_tag="L1U99_001070"
     CDS             30022..31536
                     /gene="dltA"
                     /locus_tag="L1U99_001070"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HBN1211626.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            31533..32738
                     /gene="dltB"
                     /locus_tag="L1U99_001071"
     CDS             31533..32738
                     /gene="dltB"
                     /locus_tag="L1U99_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBN1211627.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            32783..33016
                     /gene="dltC"
                     /locus_tag="L1U99_001072"
     CDS             32783..33016
                     /gene="dltC"
                     /locus_tag="L1U99_001072"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBN1211628.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            33019..34287
                     /gene="dltD"
                     /locus_tag="L1U99_001073"
     CDS             33019..34287
                     /gene="dltD"
                     /locus_tag="L1U99_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBN1211629.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            34428..35510
                     /locus_tag="L1U99_001074"
     CDS             34428..35510
                     /locus_tag="L1U99_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBN1211630.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            35510..36313
                     /locus_tag="L1U99_001075"
     CDS             35510..36313
                     /locus_tag="L1U99_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBN1211631.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            36383..37123
                     /locus_tag="L1U99_001076"
     CDS             36383..37123
                     /locus_tag="L1U99_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBN1211632.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            37134..38138
                     /locus_tag="L1U99_001077"
     CDS             37134..38138
                     /locus_tag="L1U99_001077"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBN1211633.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(38183..39880)
                     /locus_tag="L1U99_001078"
     CDS             complement(38183..39880)
                     /locus_tag="L1U99_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211634.1"
                     /translation="MKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLE
                     KPLDEANLLIKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTL
                     TVSSPYQNYAGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMY
                     KQKRLEYSLILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYY
                     WSRMFYYKKWYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLAC
                     IGEAYKNNRFYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISY
                     NLIDHILNTDKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLM
                     HTDQTKAKNYVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLP
                     EELPINDDDLAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYD
                     TNLFSRGITEELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT        12803 a         7024 c         8285 g        11818 t
ORIGIN      
        1 attaaagcgc tattggatat tttatttttt gcaaaaaact tcttgaaaat tttcattttc
       61 attgatttta gtagaaaact accgaaatgt ttggtaaaat agggtcgttg gttaagaatt
      121 gtcttaacaa atttagtttt acaaaactta ggaggaattt tattatgcca gtagtatcag
      181 gagctgaatt tttaaaagct gctcgtaaag gcggttacgc tgtcggcgga ttcaacacaa
      241 acaacttgga atggactcaa gcaatccttg aagcggctga agcaaaacaa gcaccagtac
      301 ttatccaaac atcaatgggt gcagctaaat acatgggtgg ttacaaaatc tgtaaagatt
      361 taatcactga tttagttgaa gcaatgaaca tcactgttcc agttgctatc cacttagacc
      421 atggtgatta cgaagctgct ttggaatgta tcgaattagg ctatacttca gtaatgttcg
      481 atggttcaca tctaccattt gaagaaaact tgaaattagc taaagacgtt gttgaaaaag
      541 cacatgcaaa aggtatctca gttgaatgtg aagttggttc aatcggcgga gaagaagacg
      601 gaatcatcgg taacggcgaa ttagctgata ttgaagaatg caaacaaatg gttgctacag
      661 gtatcgacta cttagcttgc ggtatcggta acatccatgg tcaatatcca gaaaactgga
      721 aaggattagc ttttgaccac ttacaagcaa ttgctgatgc tgtaggtcca gacatgcctt
      781 tagtattaca tggcggatca ggtattcctc aagatcaaat cgaaaaagct atctcaatgg
      841 gtatctcaaa agtaaatgtt aacactgaat tccaattatc atttgctgca gctactcgta
      901 aatatatcga agctggtaaa gataaagaag gtaaaggatt cgaccctcgt aaattattag
      961 ctccaggtaa agcagcaatc gttgaagatg ctaaatctca tatcgactgg ttcggttcag
     1021 ctaacaaagc gtaagcatcc acataacaga tacgatatat aggaatggag aacgactttt
     1081 gaagtcgctc tccattcttt tttacttaaa acggcagacc atgctcgttt ctttttttta
     1141 tctatgataa aatacaagca tatccatgaa aaaagattaa taaacaaggt ggaaacagat
     1201 gaaaaaaatc gtaatcaaag gaaaccgacc tttagctggt gaagtaacga tcagcggtgc
     1261 aaaaaatagt gcagtcgcat tgattccagc tgcaatctta gctgattccc cagtgatctt
     1321 ggaaggtgtg ccggacatac aagatgttca ttcattaatt gaaattttag agatcatggg
     1381 cgcaactgtc catttttcca acaacatact agaaatcgat cctcgagaag tcgtatcgat
     1441 tccgatgccg cacggaaaaa tcaatagttt gcgtgcttct tattatttta tgggaacact
     1501 gcttggtaaa tttggcgaag cggtagtagg cctgccaggt ggctgttatt taggccctag
     1561 accgattgac ctacacgtca aaggatttga agctctaggt gctgaagtga caaatgaaca
     1621 tggtgccatg tatttacgga cagaaaataa aggattgcgt ggcaatcgga ttttcatgga
     1681 cgtggtttca gtcggagcaa cgatcaatgt gatgttagct gctgtaaaag caaaaggaca
     1741 gacagtaatt gaaaacgctg cacgagaacc ggaaatcata gatgtggcaa ctttactgaa
     1801 taatatgggg gcaaaagttc gaggagcggg tacagatgtg atccgtatcg aaggagtcga
     1861 aacattacat ggctgtcggc atttcatgat tcctgaccgc atcgaagcag gaacctatct
     1921 agcattagca gctgcagtag gaaatggtat caaagtgaaa aatgtgatct ttgaacattt
     1981 ggaaagcttt atagcaaaat tgcaggaaat tggtgtccat atgaaaatca gcgaagatga
     2041 aatcgaagtt tacccctcga aagaattaaa acccgcaaac atcatgacct atccttatcc
     2101 aggatttgcc acagatctgc agcagccact tactgcgtta ctattgatga ctacaggcac
     2161 ttcagaaatc atcgatacga tctatgcgaa acgtgtgaac catgtgccgg aactagcacg
     2221 aatgggcgct gatattaccg tggaaggaaa tatgatcatc gtgaatggtc caaataaact
     2281 tcacggcaca gaagtcgtgg cttctgatct tcgggcaggt gcttgtttag tgattgctgg
     2341 actattggca gaagggacaa cgacgattta caatgtagat tatatcttac gcggttatga
     2401 tcatattatc gagaaactaa cagccttagg ggcatcaatt gaaatgatag aggaagtggg
     2461 agctgaatga gcgattattt gacaatggca gaactagaga acaaaacgtt aaaagaagtt
     2521 tatagttatg ccaaagaatt taaaattcct tattacagta agatgaataa aaaggaatta
     2581 tctctagctg tgattcgtgc acaagcagag aaacaaggat tttattatat ggaaggaata
     2641 ttggatatcg ttggtcaaga tggttacggt tttttacggc caatcaatta tggaccaagt
     2701 gcagaagata tctatatttc tgcctcacaa atcagacgat tcagtttgag aaatggggac
     2761 aaagtggcag gaaaagcccg tccacctaaa gaatcggaac gttattatgg tttgatgcac
     2821 gtggaaagcg ttaatggaaa agatccggaa gaagcaaaag aacgtccgca ttttccagcc
     2881 ttaacacctc tttatccgca aagacagctt caactggaaa caacaccgca aagactatct
     2941 acccgaatga tcgatatctt ttctccaatc ggttttggtc agcgtggatt gatcgtcgca
     3001 ccgccaaaag cagggaaaac ttctgtatta aaagaaatcg caaatggtat caccgaaaac
     3061 tatccggaag tagaattaat cgttctactg attgatgaac gaccggaaga agtaacggat
     3121 ctagaacgaa gcgtgaaagg cgacgtggta tcttctacat ttgatctgca gccgcaaaac
     3181 catactcgag tttctgaatt agtattggaa cgcgcaatgc gtttagtcga agataaacga
     3241 gatgtcgtta tcttgatgga tagtattact agacttgctc gggcctataa cttagtcgtt
     3301 ccaccaagcg gacgtacatt gagtggcggg attgacccag ccgcattgta taaacctaag
     3361 aaatttttcg gggcagcaag aaacatcgaa gaaggtggca gtttgacgat tttagcgacc
     3421 gctttagtcg atacaggaag ccgtatggat gacgtgatct atgaagaatt caaaggaact
     3481 ggaaatctag aattacaact ttcacgtgaa ttatctgaac gtcggatctt cccagccatc
     3541 gatatcaaaa aatcaggtac ccgaaaagaa gaattattga tgccaagtga agaattagaa
     3601 gaaatttgga aacttcgaaa aaatatgact ggagattcat tagaatatac ggaacaactg
     3661 atccgctttt tgcgtaaaac aaaaaacaat cagcaatttt tcaaagaatt tcaagatgtc
     3721 tcctttggta aaaaaaatcc gaccagaaat ctgaaaagat aattgcaacc ttgactgaaa
     3781 catgttaaga tgttaatgtt gtaaatcgac aaatcaactc tggttcagca aatggagcag
     3841 ggcaaaggag cgaaaaaatc atgaaagaaa acatccatcc agattaccac ccagtagtat
     3901 tcatggattc aacaactggt ttcaaattct tgtcaggttc aacaaaaact tcacaagaaa
     3961 cagttgaatg ggaagacggt aatacatacc cagtcatccg tgtcgaagta acttctgact
     4021 cacatccatt ctacactgga cgtcaaaaat tcacacaagc agacggacgt gtggaccgtt
     4081 tcaacaaaaa atacggtctc aaagacgcaa acgctgcgga ataataaaaa cgctgataac
     4141 tcaacgttta gcagactatc tgatagggat agtctgtttt tttatgtttt ttgccaattt
     4201 aaaacttcgt ttgatgctga aaaagtcgta ggatcataat gcacaaaaca atgaaaaact
     4261 agtatatagt tttaattatc cacttgataa aaacacctta tattaacgaa atgaagaggg
     4321 gttatttcga agtaaaaaac catttaccta aaattagaag ctaagctttc ctttcaagga
     4381 aggctttttg ttttgttata gacttgcgat tgtttgtgag ctagatcgtt cattttaatg
     4441 acttatacac gcggatgatg ggtctttttc ctctgttcat tcataatatt gaacggtaca
     4501 gctagcgatg ctatactgac ctcagttcca agaaaacgtt aacatttttt gtgggggaga
     4561 ggttttttat gaggtttgat caattgatcg cagaagaact gattgttttc gatccatcga
     4621 tagattcaaa aggatcatta tttgagcgaa taggggatgt gttgaaaaaa acaaataagg
     4681 taagaaatgt tcaaaaagtc gttaaggcac tattcaaacg agaggaggag atctccacag
     4741 gaatagaaga tggatttggg attccccatg caaaaagcaa atatgtgaca aaaccagcac
     4801 tgtgtttttt tcatacagcc aaattaacgg actatagcgg gatagatgaa atgccaattg
     4861 aatatatttt tgccatcgta gttcctgaaa aatcagcaga tatgcatcta gagattctca
     4921 gcacactctc cagacgattg atgaatgcag attttagaaa gggaataaaa gaagccacta
     4981 cgccagcaga tatcatcaga cagattagtc aagaatgaaa atagtagagt ctttgtccga
     5041 gtatcgatag tgaagaaaaa ggaggaaaat aatcatgaaa atcgttggtg taactgcttg
     5101 cccgactgga attgctcata cttatatgtc ggcagaaaaa ttagaagtaa cagcaagaaa
     5161 tctaaaccat caagcaaaat tcgaaacaca aggtgtaaaa acagaaaatc agttatctga
     5221 acaagaaatc aaagaggcag atgcaatcat tcttgcagta gataaagaaa tcgaattgga
     5281 ccgatttgcc gggaaaaaag taaagcgtgt ctctacaagc cgagcaatca aagaaccgca
     5341 agtagtaata gacgaagcat tgagagatat tggcgtattc gttgtgtcta atgaaaaaga
     5401 accagctgca aatgagaaaa agccgacaat ctataatcat ttcatgaatg gtgtgaatta
     5461 catgcttcca tttgtgatcg caggcggaat catcatcgca ctgagttttg cctttgggat
     5521 tacagcggct gatcccaact cagcagacta taatgtgtta gcagctgcat tttcaaggat
     5581 cggaggagat acagcgtttg ccatgatggt tcctgcgtta ggcgcgggga ttgctacatc
     5641 gattgctgga aaagcaggtt ttgccccagg aattgttgcc ggattactgg cctctacagg
     5701 tggttcaggt tttcttggcg gaatgattgg tggcgtgcta gcagggtata tctgtgattt
     5761 tctggcaaat aaaattagcg taaaaaaaga attttctgct atttatcagc tgattgtcgt
     5821 ccccttttta tcgatcttaa ttattgggct tttgatggta tttgtgattg aacaaccgat
     5881 cacatgggtg ttggatgctt tgacaaattg gctgaatagc ttgggaaata catccgggct
     5941 attgttcgga ttacttatcg ggatcatgat ggcagctgat atgggtgggc cgatcaataa
     6001 atcgacttcg actttctcga tcggtttgat gtcagctgga gtaaatgcac cgattgctgc
     6061 ttgtatggct gcaggaatga cacctcccct aggtattgct ttagccactt tattattcaa
     6121 acataaattt accaaagaag aacggacttc aggtcaatca tgctggattt taggcgcttc
     6181 gtatattaca gaaggtgcta taccgtttgc ggtatctgac ccgatccgcg tgatacctag
     6241 tttgatgaca ggttcagcag tcgctgcagg gatttccatg gcagtaggag ttacttcaat
     6301 ggcacctcat ggagggattt gggtgatgct aattccaaat gttatgaaca atttacctat
     6361 gtatgtcttg gcaattgcat caggtacagt cactacagcc tttatgcttg gactattgaa
     6421 aaaaacagtg aaagagaaaa aacaagacaa gtggacgaaa aatgaaaatc taacaaatga
     6481 ggtggaagcg taatgttata tacaatgaaa gagttattga aagtggctaa agagaatcaa
     6541 tttgcagtac cagccttcaa tatttgcagc tatgatatga tgaaagcaat catcgaagaa
     6601 gcagagagat tagaagcacc agtaatctta gaaattcatc ctgatgaaat cgcctattta
     6661 agtgatgagt ttgttgcggc agtaagagcc tatgcttata caagtaaact gccgatcgtt
     6721 atccacttgg atcatggcgg tacgatagaa gatgtcttac gggcgattcg aaacggctat
     6781 tcttccgtga tgatcgatgc gtctttgaaa tcattcgacg acaatgtaca gattacgaaa
     6841 aaagtggttg cgttagctca tgcggtaaat gtctcagtgg aggctgagct tggaacgatt
     6901 gggaataatg gttctgctga aggaggtgct gaaacaatca tttatacaga tcctgatcaa
     6961 gcgaagattt ttgtgaaaga aacaggaatc gatacacttg ctgtagcaat tggaacagcg
     7021 catggcttgt atccgaaaaa cagaactcca aaattaaata tcgacttact gaaagaattg
     7081 aaccaacaaa tcgatcttcc atttgtttta catggcggtt caggtaatcc ggacgcagaa
     7141 gtcagcgaag cagtaaaata cggagttgcc aaagtgaatt tgagctcaga tcttaaaagc
     7201 gtctttttca atgctttgag agaaatattg agtgaaaatc catcgatgta cgagccgaat
     7261 gcaatttatc cagcagctaa taaaaaggta caagaagtgg tcaaacataa aatggaaatt
     7321 ttgaacacag taggcaaggc tagtttatac taaaaataaa aatgtgtggt caagagggta
     7381 tgacaatagt cttgtcatac cctcttaacc acacacgatg ttcagaagta gttttttcga
     7441 aaaatttctt cttatttctc gaagccaatc acttctgtca caacctcttt tttcctgtta
     7501 ctatataaag taaatggggt gattttatgt tgaatgaagt ggagaataga cagcaggaga
     7561 ttgtgaatta tctaaaaaac aaccaatttg caagagtcac cgatttgatc gagttagtaa
     7621 attatagcga agccacgatt aaacgtgacc ttgtttttct ggaaaaaagt ggattgatcc
     7681 gtagagttcg cggtggcgcc atgcttattg acaatcgaaa aattgacgtg ccttacctga
     7741 tgaagatcac caaattagaa gaagaaacag aaaaacgtaa gattgcagat acagcttctt
     7801 ctttgattcg agatgatatg gtcttattct tggattccag tacaacctct ttacacttag
     7861 tcagaaacct agcaagattt gatggtttgc agatcattac gaatggcatc gtcacagctg
     7921 ctatgttgag tgaatataca acggcaaaag tatctgtatt gggaggggca attgttccga
     7981 aacgagcaac aatcaacggt tcaaaagcct ataacgatgc attgtcatat tatgcggatt
     8041 tagcgataat gagttgtcgc gggctagatt tcagccaagg agtaacagaa actcatgaag
     8101 gagaggcaat ggtcaaaaaa gcttttagaa aacaatcaga ccggcttgcc gttttagtta
     8161 cacagcaaaa aattgcacat aaattcatgc atcaagccat tgcttttcat gaaatcgatt
     8221 atctggtgac aagtaaagaa ctgacaaaag aacagtatgc gaaagtaaag gaacaccata
     8281 tcgaatgtct gtacggataa attattacgt gaatgttcta agtggcttcc tcatttttag
     8341 ataggacctt atctttgctc gcttctctca gccgatggta taataatgaa aaggttatct
     8401 tgttagataa tcttactttt ttatccagga gaaaggagtg cagaaaatga aacatgtgaa
     8461 ggcgttggta gtgaaggcaa tcatgatctg ggcgattctg tgggtcgtgc tgacaggttt
     8521 atacggtgtt agctttatgg attcaacgat tgttggggta attattgtag tcatgatcta
     8581 tgtgctaggg gatctgttga tcttacgtaa agtagggaac atcgcagcga cgatcgcaga
     8641 tgctggttca gctgcagtta tcttgtggct ctatctatat tttatgaatg atacagtcga
     8701 tatttggatg aaagtattga ttcctgctct attgatcggt gtggcagaat ggttcttcca
     8761 caagtggttg ctaagtcaag gcatcgtacc agatgaacgg aaaatggaat aaatcaacag
     8821 ttaaactatt cttatcgata aatgaaagct ttaaaaataa atagatgttt aattaagaat
     8881 aatcataaac tatttttact caaaaaaccg ctcagattat tttcagatct gaacggtttt
     8941 ttttatctat tcatcaagat caaatttcat ttttcaatga ttcaatcaat tcgccctctg
     9001 cttcatgact atgttttcgg ccattaacaa gatagagtgc tgtacatatc aatggaatga
     9061 ctccggcaat cacatacaat cctctaaatg aagtaagaga ttttagcatc cccatcaaat
     9121 aaggaccaac gcctaagcct aggtctaaac caataaagta ggtagataaa gcaatactga
     9181 ttcgatgttc gcggacgatt tttaaacaaa cagcctgtcc atttgacata aacgtaccat
     9241 aacctaggcc gactaatgct ccagagataa gcaatgtcac actattcgtc gttacactca
     9301 gtaaaaataa tcctgctgtt aagaataaat agctaggata catcacgtat tgttctcctt
     9361 tgacatcgaa aatccttcca gtcaatggac gtgtaaatgt gatgaccaaa gcatatacga
     9421 cgaagaaaaa tgacccagca gcaactaagt ggattacttt tgtataagaa gataaaaatg
     9481 ataaaacact tgaataagaa agacccatca aaaaggcaat tcctgtaatg aaaagtgctt
     9541 tcttttcaat aaaactattg atattccatg agcgaagaga tattttttgt tcttcagata
     9601 atggaatatt ttttacagga aagacaaggc aggcaatcgt aacaaagaag accagtacaa
     9661 ttgaaaacca gataatgaaa cgaaaatcag tcatattcag caaaatcatt cctaaaaatg
     9721 gcccaacagc ggcagctaaa ctagtactta atccataata attgatgcct tccccttttt
     9781 tagatgcagg gatatatgca gtaacgatag catttgtagc tgtagaaact gtaccgtagc
     9841 cgaatccatt caagaatcga actaaataca atgccccgat agttggcgta taaagatatg
     9901 ctaatgttga aaggagatag aagatcgcgc cgcctcttaa ggtaaacttc cgaccaaata
     9961 gttctaactg tttccccatg aataagcgtg ccagcaatgt tccgatgata tagatcccag
    10021 aagcaaaacc tgcttggctc aagctggcgt gtaaggtgtc ttgcgcaatg actgccatga
    10081 tgaccatcaa cagataataa atcaggtaga caataaaatt gatcaatgtg attccaataa
    10141 aatatttatt aaataatttc ttttccatgt atgttataca ttccccttaa gctgaatatg
    10201 cttttaattt ttgtatttga acttctacat cgtgataatt ggatggatag cgatcaacaa
    10261 gttggcgaat aaataaatct cttgtagaca taaacagatt taaaaattct tcgcattcgt
    10321 ttgttggatt ctcatccact gctttgatca attcgatcga gttttgatac gcatcattta
    10381 aaaagactaa agaagctttc atatcaaatc ttgtttgata tgctgtttct aatcgattaa
    10441 tgattgtgtt catccagtaa ttcatgtttt ttccctctat tcttaaaaaa ttttacttct
    10501 gcagtataac gaataaaaaa aaggaaaaaa atcgcataag tgatggaaaa aggtacttaa
    10561 caaatgttaa tatcattagt aaaatacctt tggactttaa aaagttttaa agtactgtat
    10621 gatcttttta gatgaaagtt tggatggggg agcatcattg gatagtagag tcttaaagga
    10681 atatttggat aaaaatgatt ttccgattat acgcaaagga tatcataaat atttgacatt
    10741 cgaagggatg gaagattccc atacgtatat cttgaaagag ggaacggtaa aagcaagtgt
    10801 tatttcaaat gatgggagag aatttaacct tcgctatatc aaagatcttg aaatcgtctc
    10861 tcttttaaaa gacgaatatt cacaattcat cgattcgccg tataatattc gagttgaatc
    10921 agaatatgca gagttttatc gaatcaatcg tgtgcgcttt tggcaaaata tcaaccaaga
    10981 cccaaagcta caacactatg taaaagagta ttaccgctat cgtctgcttt attcgatgaa
    11041 aaaaatgcag caaatgctat taaacggaaa gctgggagct gtttgtacgc aactttacga
    11101 attatatgat ttattcggtg tgcggacaga agaagggatg ctgatcgatt tttcgatcac
    11161 gaatgaagaa atcgccaaat tttgtggcat ctcaactgct agcagtgtaa acagaatttt
    11221 aaaacaactg aaaaaagatg gtattatcac cgttaaagac catcatatcg ttattttgaa
    11281 tatggacttg ttagaagaca atattatctt ttgatgaaca aagaggttgt gaaatcagcg
    11341 ttttgacctg agtattagag aaacaaacgg aaaaatagtt cctcatattt tgccgttttt
    11401 tgagctaata ccgagggtca gctgattgaa caccgtttac caagaggttg tgagcctgcc
    11461 gtttaactct gagtcacaag gaacaatttc aaaaaacagc ttttcatgtt tgatgaatat
    11521 tgtgacttgt gaccgaggag ttggtaggag aacaccgttt accaagaggt tgtgaaaaag
    11581 ctgttctgca tcaagtaata agaagagcca agtaaaaaca gtctcttatg tttttaactt
    11641 ggctggactt atcaccgtag atgtaagctt ttgaacgccg tttatttgca acaaaagggg
    11701 ctgtgacacg atttttgtca cagccctttt tttgcgaaca ttcatttagc aatttttaga
    11761 aacttctgcc gccaccgcca aaagtcccgc caccgctaga atgggtagta cttccgccac
    11821 cgccgcttcc aggaggtggg cttttgggga ttcttcttgt cgtgacaaaa gaatttgtca
    11881 gacgatcggt tttttcagtt aatttgatac tggatttttc tcggaatgga tatttgtaga
    11941 tgcctgattt caattgataa cgcgaaacag tcacaaaata aaagacaaga ctaaggataa
    12001 gagccaaaac aacagcaatg atgatttcta ctgtcgtcaa aaccttatag cgtgtaattt
    12061 tgccagtttc ttcgtctaca cgataatgtc ctcctggaac tccgtcttcc acatatgttg
    12121 ctgatttaga caggtaagct tttgcagcat tgtaataggc agcatttgtc atctgatcat
    12181 aaacatcatc taagatcgaa tcgattctgc tatcagtcaa ataatcgatc atattaccag
    12241 aagtcgaaat gtagatttca cgctgtccca tatctaatag caatactgag ccattttgat
    12301 catttccgac tgcgtctctt aagtaattat cagcaaagtc tcttggttct tctgaattag
    12361 atgtagtcgt tacgatcaag actcgtcctt tgattttttc attcagcttt tctgcctgtt
    12421 gttccaaaga ttggatttga tctgttgtga ataacccagc ctcatcattt accgtagctg
    12481 tatctgcatg agtagccacc ggccagccaa cacttactag caaaagaaag aataaaaaaa
    12541 attttttcat catatcaagt aacctccgat cagaaagagg atcgctagcc cagcgaaaat
    12601 cccaagagcg gtcagtccca attttttctg gctgatcggc aggacaccgc tgacctttcc
    12661 tgtttgtcca ttcattgcgt agtagtagac ttttttactt gagtcattgc ttcgataagt
    12721 aacaagccat accggcagta atacgtaatt atttacttcg tttgtgattg aagcagaagt
    12781 tcgcacaccg gtcaatgttg tatatccatt tgcggtatct tttaacagct tctctgaata
    12841 gtcttttaat tcagattgaa tctgtgattt gattgcctca tattcgatat ctcttttttc
    12901 tgcttggaac ccggctaaat actggctttt aaaatcaatt gctttatcta acgggaaagg
    12961 ttgcacgcct tcgaccatct tttgttgcgt attttttgat aaggcatttt ttactagttc
    13021 tttaaaagaa agcttgcctg ctcttgaaac agcaaattgc ttcgtttctg tgtattcgat
    13081 gtcacctatc cgccatatgc ggataactgt accattcgcc tgcatggcac catctacttc
    13141 agcatctgta gcccaataag ggaaatacac acctgtcaac ttatcgattt gatccttatt
    13201 gaaaaaagct ttgggaacaa accatttttt cttggtccaa gcgagaaatc tgttgattgc
    13261 ttcttctttc tcgacagcaa aaggaagtac tttatttggc aagaattctc cgcttaaacg
    13321 tcccgatagt acgacgggat tatggcagta gtaacaataa gtcgcagcag ttgtcgcatc
    13381 agtcacgatc tctgcaccac agttgggaca aagaaaaaga tctatcgctg cggtattatc
    13441 tgcagattcg tccgctgtat ctgaaaaacc gcctgcctcg tcaaccgctt tgcgctcggc
    13501 ttcattcata tcggcaagct gttcttgggc tgtaaaagta aaatcttcgg taggtgaagg
    13561 ttcttctttg ctttcttcgc cagccatacg cgcttctttt tgcttttgct catattggct
    13621 gacttcttct tctgtataga tattcaggca gtattcgcaa tgaaattttt ggtctttggg
    13681 atcaaaagtc aacggaccgc cgcaattagg acatttatgt gtaagaacat ccatcagctg
    13741 cacacctttc taaataaatt aattaacggg gattccttta aacggtttac cacagtttgg
    13801 acagaattta gggatgccgt tggaaagatc cacgatctca ttgcattcac tgcatcgcat
    13861 ttgtagctta ggctgaacgt tttctacagg tttggcagct ccgcagttgg aacagaattt
    13921 tccggaattt tctgtcccgc aaactggaca tgtccaagta tccgcatttc cttgtgcagt
    13981 ttgttgattt tgtttttctg cttgttgttt gatttgttct tggttatttt gagctgcttg
    14041 agaaagataa gaaccatttg cattcattcc catacctaca cccataaagc cggtcattgc
    14101 tcctgcttca ttttttccgg ctgcttccat accacgtgca atggaacctt gcacgtagcc
    14161 ttcacgtacg ctaggatcac ctagcatcgc cccttcgtta cgcatattga tcagtttcac
    14221 agaatcatcg gtgtaagaaa tgctggctac agccacagaa acaatctcca tcccacgtaa
    14281 ttcacgccaa gaatcatcca atgcagtatc catgtatttg cttaattcca aactcttaga
    14341 tggtacataa gaaatccgtt gaccatctgc agacatctga ttgattgctg attgtagcgc
    14401 tgttaggaat tcagctaaat actgctcatt gatatcattg atttccactt gtgttttgtt
    14461 tttagggatt gcgtttgtat aaaataaaat cgggtcaacg acatgaatag aataagtgcc
    14521 atgtgcccgt aagaataatt ctgcgttata gaaattgtca aagtagttca acggcgcgct
    14581 tgtaccgaat ttgattccct ttatttcttg gagattgata taaaaaactt gttgtttctg
    14641 cggtgtgacg ccgccaaatt tgaatcggtc aaaagtttca gcaattgctt ctttcagtgt
    14701 tccattgaac atggaaggag ctgcgtcatt tttaatggtg taataacctt cctcagcggt
    14761 ataatcgatg atttttccac catcgaccaa aagcatcatc atgtttggat agacatggac
    14821 gactgttccg tctgttaaaa catcttctgt tcctttacga ttggagccac gtttgtcatc
    14881 tttgcggact ttgacacctt ttgtcatgac cgttgtatca ctcatattgt ctggttcgat
    14941 gacttctagc cattgatctg ccagaccgcc gccaaccata cttgttgctg ctttgataag
    15001 acccataaaa aattcctcct ctgattcagc tagtgccaaa caattattgt ttatttatta
    15061 taccatagga agatgtgaaa cttctcggac tagagacgga attgaaatgg aaaattgcgt
    15121 attgtttaaa tacctgaaaa agccgagaag gatagtagtt tttttaccta atatcacgta
    15181 taataagaga tagtgaattt tttaaaaaag ggggatcctt atggcatatc aagcacttta
    15241 tcgagtctgg cgttcgcagc gtttcgaaga catcgttgga caaaaagctg tgacacagac
    15301 actaaaaaat gctattgttt cccacaaaac ctcacatgcc tacttgttta caggacccag
    15361 aggaaccgga aagacgagtg cagcaaagat tttcgcaaaa gcaatcaact gtccgaacag
    15421 taaagacggt gagccatgca acgaatgcga aatgtgtcga tcaattactg ctggtacgca
    15481 agaagatgtg atcgaaatcg atgctgccag caataacgga gtcgaagaaa tccgatttat
    15541 ccgtgatcgg gcaaattatg cgcctacaaa ggcagcgtac aaagtgtaca ttattgatga
    15601 ggtacatatg ctttcaacag gagctttcaa tgccttgttg aaaacattgg aagagccaaa
    15661 agaaagtgtc atattcatct tagcaacgac cgaacctcac aaaataccag ctacgatcat
    15721 ttcacggact cagcgatttg attttaaacg gatcaatacg gcagatattg tcgaacatct
    15781 tgaatttatc ttgaaagaat cgactatcag ctatgaacca gctgcattga atgtgattgc
    15841 ccgttctgca gaaggcggga tgcgggatgc attgagtatt cttgatcagg caatctcgtt
    15901 tagtgaagga acaattactt tagatgatgc catgcaagtg acaggtagct taactgacga
    15961 aatgatggac agttacttga gtgcttgcgt gaaaaaagaa gtaccagaag cattggaaac
    16021 attgaaccaa attctcgcag ccggcaaaga atcacgtcgc tttctagagg atatgttaca
    16081 atactgccgt gacttgctga tgtatcagca agcacctaac ctagttgagg aacaatcgag
    16141 tacgatcaga agtacattta cagaattggc acaaactgtt tcagcggatc agctgttttc
    16201 aatgataaag attttgagcg atactcaaaa tgaaattcgt tttaccaata gtgccgctat
    16261 ttatttggaa gtcgctacag tcaaacttgc acagctaccg tctgcttctg ttccttcagc
    16321 agatgtagca tttgcagatg atcagatagt aaaacagcta caacaagaga ttaaggaact
    16381 aagaaacgaa atcaaggaac tacgcagtaa tacaggaatt gagaatacaa aagtacagcc
    16441 ggtacagcaa acaaatcata aaaaacagac aagtacctat cgtgtaccga cggaacgagt
    16501 atataaagtt ctgcgggaag cgacaagaca gcatctgaac caagtaaaag aagtatggga
    16561 agacttgctg atgagtctat ctgtcactca gcgagcaatg cttaaagcaa gcgaaccagt
    16621 tgcagctgga cctacaggac tagtgattgc gtttgattat gagattgttt gtcaaagagc
    16681 agcaaatgac gaagaattgc agctttcggt acacaacaac ttaagccgaa tgatcaaaga
    16741 ttatgcgcct gatcctgttt atattacaag agaaagctgg ccagaacttc gaagaaatta
    16801 tttgacgcag gcacaagaag agggaacaga aaactctttt gcttctgaag actcagaagg
    16861 agaaatcgag ttgcttcctc aagaacaaga agtaccagaa gaaacacttg tagtaaaagc
    16921 agaggaactg tttggctccg aagctgttac agtggtagat gattaataaa aaggagtaga
    16981 taattatgat gcgtggaatg ggcaatatgc aaggcatgat gaaacaagta caaaaaatgc
    17041 aaaaagaaat ggcagaagca caagagctgc taaataaaac agagtttaca ggtaaagcca
    17101 ccaatgaatt ggtcaaagcg gtttttacag gcgatcgtcg catgaaagat atccaaatca
    17161 atgaagaagt cgttgatcct gatgatatcg agatgcttca ggatcttgtc gtaatggcag
    17221 tcaatgatgc gatcgcacaa attgatgtgg aaactgagaa aaaattaggg aaatacgcaa
    17281 aaggtttgcc aggattttag ttttaaactg aaggagtaat gaatatgcaa tatccagaac
    17341 caattgcgaa actgatcgac agctacatga aacttccagg aatcggtcag aaaacagcga
    17401 caagactcgc cttttatacg atcgatatga aagatgaagt agtaaatgaa tttgctaaat
    17461 ctttgttaag tgtaaaacgc gatttgcatt tttgtagtat ctgcggaaac atcacagaag
    17521 aagatccctg cgaaatatgt agaaatcctt cacgtgatcg aagcgttatc ctagtggtcg
    17581 aagagccgaa agatgtaatg gcaatggaaa aaatgcgaga atatcacgga ctttatcatg
    17641 ttctccatgg tgtgttatca ccgatggaag ggacaggtcc agaagacatc aatatttctt
    17701 ctctgttgca gcggctgcat gatgcagatg taaaagaagt gattatcgca acaaatgcaa
    17761 caacagaggg agaagcaaca gctatgtatc tctcacgtct gatcaaaccc gcaggtatca
    17821 aagtgactcg tctagcacat ggtctgtctg taggctctga tatcgagtat gcagatgaag
    17881 ttactttatt gaaagctgtc gaaggaagac gtgagttata aatttctaat taagtgtttt
    17941 ttcagataca atataaaagc agcacaagag atgggggcaa caatgtgaac ggactattta
    18001 ttacaatcga ggggcctgat ggtgcaggaa aaaccagcat cttgaatgaa ctttaccctc
    18061 ttttgaaaga agtagcaaaa acagaaatca ttcaaacaag agaaccagga ggcattccga
    18121 ttgctgaaga gatccgagca gtgatccttg atccaaaaaa tgatcggatg gatgaacgta
    18181 cggaagcact gctttatgca gcagcaagaa gacaacatct agtcgaaaag gttctgcctg
    18241 ctctggcaaa agggaaaatc gttttatgcg atagatttgt cgacagttct cttgcttatc
    18301 aaggtgcagg ccgacgcatc ggcgttaccg agattgctcg gttgaatgag tttgctacag
    18361 aaggtactac gccggatttt accctttatc ttgacgtaga ttcagacacc ggattaagaa
    18421 gaatcaagaa aaacagacaa aatcaaatcg accgtttaga ttcggaaggt ttggaattcc
    18481 accagcgtgt acgtcatgct tacttaaagc tggcagaaga gaatccggaa agaatccaca
    18541 aagttgatgc aagaaaaagc tttgaagaag tgctgcaaac aagttatcat acaattattg
    18601 aacagtatcc gcaatttttt gaaaactagg aaggtgaacg tttatgaaaa ttattttagc
    18661 gattatccaa gacaaagaca gcaaccgttt atcaaatgaa ttgattgatg caaatatccg
    18721 tgccacaaaa ctatcatcga caggcggctt ccttaaggct ggaaacagta cgtttatcgt
    18781 gggtattgaa gatgaccgtg tagaagaagc attggaaatc atcaaaaaaa cgtgtgaatc
    18841 aagaaagcaa tttgtatcta cacctgttac actggatatt tcgatggatg ggggcgtccc
    18901 ttatccagta gaagtagaag taggcggtgc cacagtcttc gtcttacctg ttgaaggatt
    18961 ccatcaattt taggaggagc tgagctatga atcaagaaat aaacttggct caaatgcaac
    19021 cgatcgtgta tcagcagctt caacggagtt ttgagcatgg gcgtatcgct catgcttatc
    19081 tttttgaagg ggagaaagga acaggaaaac atgaagtagg tatatggctt gcacagcacc
    19141 tgttctgtac ccaaatgaaa gacaatctgc cttgtggaaa atgcaacaat tgtcagcgga
    19201 tcgaaaagaa agaacatcca gatgttttgg ttattgaacc ggaaggacaa accatcaaag
    19261 tcgatcagat cagacgtttg cagacggaat tcagtcgcag cggttacgaa tcaagaaaaa
    19321 aagttttttt gatcaaagaa gctgaaaaaa tgaatagcag tgcggcaaac agtttgttga
    19381 aattcttgga agagccccct ggagattttt tagcggtgtt agaaacagat gcagtaggaa
    19441 gaattctccc tactattcaa tctcgttgtc aagttctgca ttttcaagaa ctttcgaaag
    19501 aagcactgat ccatcgattg caagaagagc agattccatt ggaaaaagca aaacttttgg
    19561 ctttcttaac aaacagttta ggaaaagcag ttgaaatctc tcaagatgaa tggtttaatg
    19621 atgctaagga cttgatttat caatggttcg tttacttgca aaagcaagat actcaagcct
    19681 ttatctatgt ccaaaaaaaa ttggtaaaat catttaaaga aaaaacacaa cagtttacag
    19741 gattatctgt cttgatgttt tattatcagg aagcacagcg tcaagcagta gcaaacggcg
    19801 aatatggcaa agtgaaacag ataaaccaga taattgaacg gatattgatc gcagagcaga
    19861 aactacgcag caatgtcagt tttcaggctg ttgcggaaca gttcgttttg catacgattt
    19921 tttagcttgc cgcaaaggat gatgatcaag gaggatggaa atggtagaag tagtaggtgt
    19981 ccgatataga gatgcaggtc atatctatta ttttgcacca ggagactctg aatatgttta
    20041 tagtgacaag gtattagtcg aatctcagca atccttacat attgctactg ttgtccttcc
    20101 taaaaaagag attgatccca atgaccttcc tgaagctatc cgtccgatct tgcataaagc
    20161 gtcacaagct gaattagaaa aagacaaaaa aaacaaaaaa gatgcttatg atgcattgaa
    20221 aatcgcaaaa gaaaaagtgc agttgcgtga gttggaaatg aaaatggtca aagccgaata
    20281 cacatttgat cgaaataaat tgattttttc tttcacagcg gacgggcgaa ttgactttag
    20341 agaattggta aaagatctgg ccgctgtatt tcgtactcgt attgagcttc gacaaattgg
    20401 tgtccgcgat gaagcaaaga taataggcgg aattggtcca tgtgggcgtc cattatgctg
    20461 ttcttctttt ttaggcgatt tcgtgcctgt atcaatcaaa atggcaaaag atcaaagttt
    20521 atctttgaat ccaacaaaaa tttccggttt atgcggacgc ttgatgtgct gtctgcaata
    20581 tgagagcgaa gaatacgaga cagcgaaaaa agaactccct gactttggaa aagtaattgc
    20641 tacacctgat ggtaaaggga aagtcgtagg gttgaatctg cttagccgta tcgttagtat
    20701 tcggctgact ggacgggaaa atcctgtcga atatgaatgg gatgaattga aagaatttat
    20761 ccaagtaggt gagatgaatg gataagagat cattatacga cggattgaat caattagaat
    20821 cagagttgag aaatacatta acagaacttg ttgaaatgaa gcatgctttg catgagatcg
    20881 tagaaaaaaa tacaactttg gagatggaaa atcaacgtct gcgggaacac ctgcgggaat
    20941 tgaaccaagt tgcacaagct ccagctgaaa atgtgaagca ggaactttct aagtctcgta
    21001 tgaatcttga aaaaatttat gaagaaggat tccatgtctg ctacgattta tatggatcaa
    21061 gaagggacaa tgacgagcct tgtgcgtttt gtctagaagt gatctatcgc gaaagcggtc
    21121 gatgaccaat aacaagagga gactggagcg gagaaatact gcttcagtct ttttattaag
    21181 gagattgtga cagatgtata atcaaaaaag tttcaaggga aatccggtat atggggattt
    21241 atatcttgta ccgacgccaa ttggaaattt agaagatatg agctacagaa gtgttcgtat
    21301 gctgcaagaa tccgatctta tcgcaagtga ggatacgcgt aatacacaaa agttattgaa
    21361 tcattttgaa atccatacac cccaaaaaag tttacatgaa cataattata aagaacgtgt
    21421 ccctcaattg attgctttgt taaaagaagg aaaaacgatt gctcaagtca gtgacgcagg
    21481 aatgccttcc atcagcgatc ctggacatga gctagtttta gcctgcataa aagaagggat
    21541 ttctgtgatc tctatcccag gacctacagc tgggatgacg gctttgattg cttcagggct
    21601 agtgcctcaa ccatttttat tttatggctt ccttccacgt aagaaaaaag aacagaaaga
    21661 aacattgaaa aagctaaaag aacagacagt tacgctgatt ttttatgagt caccttatcg
    21721 gatcactgct acattgacga atttcttaga aatttttgga aatcgccaag tcgttttgtg
    21781 tcgggaattg acaaaggtcc atgaagaata ccttagagga agtacggaag agctactcgc
    21841 ttatatcgaa gaacatccag taaagggtga atgttgtctg cttgtagaag ggaatttgtt
    21901 cgaaatgcca gtgacggaag ttgatgaaga gttgggaacg ttaaaggaac aagtagaagc
    21961 aaagatcgct tcaggcgaaa aaccaaatgc tgctatcaaa gcagtagcgc tgaaaaatgg
    22021 gctgaaaaaa caagaagtct accgtcagta ccatgaatta gactgagata gtataagttg
    22081 tctataatga aagactaatg aggaaatcag ctactaactt ttcaaatctc ttgaacgcga
    22141 acgaatgttc ttgtataatg aataagaggt gaggatgatg gagctgcaat ttcctttaca
    22201 taatgataca tcaagaaaaa tcattcatat tgatatggat gcttttttcg cttcggttga
    22261 agaacgagat catcctgagt ttcgcggaca tccattagta attgccagac accccagtga
    22321 cactggtggg cgtggagtag tgactacagc aaattatgaa gcaagaaaat tcggaattca
    22381 ttcagcaatg agtgcacaaa aagcgtatga gctttgtccg caagccatct ttaagcctgg
    22441 cgaccatcat aaatacagcg atatttccaa acaagtacgg gaagtattct atcgttatac
    22501 agatattgtg gaaccagtta gtatcgatga agcgtatctt gatgtgaccg aaaataaaat
    22561 caattgcaag tcagccatca aaatcgcccg aatgatccaa gcagatattt gggagagtgt
    22621 ccagctaaca tgttctgcgg gagtaagtta caataagttt ttggccaaat tagcatcaga
    22681 ctatcaaaaa cctagaggaa tcacggtagt tgcccctcaa gacgctgtgc catttttaaa
    22741 agctttgcca attgaaaaat ttcatggggt agggaagaaa actgtaccta gaatgcatga
    22801 gctagggatt tatacaggaa aagacctata tgaatgcaca gaaatgatgt tgattcgaaa
    22861 ttttggaaaa atgggctatt ctctttatcg taaagtcaga ggaatccatg attctccagt
    22921 aaacgttaca agagagcgaa aatctgtggg aaaagagcat acttatgggc agccgttgca
    22981 aacggaagaa gcagtgctga ctcagttgcg ccaactagct gaaaaagtag aagaagcact
    23041 gagaagagtc caaaaacatg ggaaaacagt agttttgaag gtcaggtaca cggactattc
    23101 tactgtgacc aaaagagtga cattgccaga atatatctat aaaaaagaag cactctttta
    23161 tcaagcaagc cttatatggg aggaaatctt gggagtagaa aaaggaatcc gattgttagg
    23221 gattactttg acgaatctgg acccgatgac ttatgaaaac atcgtccttc cattatggga
    23281 aaatcaagaa atataaaaac agctttgaga gttgaaaccg gaaatccgtt ttctctccca
    23341 aagctgtttt tatatcaagt cttgcttttt gatttgttca taggtttctg ttgcatccgt
    23401 acatttttcc caaatcacaa cttgattgga ttctaaagat ttttggacgt caatgatccg
    23461 ctggttgcta cttccgcgaa attgtagttt taggtcacgt ttgcttaatt caaagcgtcc
    23521 gtcaacaagg atatcgattt gcgaaaggag ttctaattta tcttctgaat cttgtagcaa
    23581 ttcatcaaag gtatagcctg tccatgacca gatatctttt gtcgtaccga actcttttcg
    23641 gatacgtcgt acgacttgca gacaaacatc tgtattcaaa aaaggttcgc caccaagtaa
    23701 agttaatcct tgcacgtaat cgttgcgcaa gtcagcgatg atttgttctt ctaattcagg
    23761 tgtgaatggt ttgccatatc gaaaattttg tgcagctttg ttgaagcagc cttcgcaggc
    23821 aaataagcag ccactaacgt aaagactgtt gcggacacct tcaccatcga caaaattaaa
    23881 cggtttgtag tcagcaatat agttttggct gtagtctttt gctaaccatt cttttggttt
    23941 tggatttctc ataaaaaaac ttctttcatt taaggttcaa agatatagct attgaagata
    24001 aaatctactc gaccacataa ataagaacaa actgacctaa atccattgtt caagaaagct
    24061 tgttcttatt ttgatagagg gcgttcaaag atacaaagcc atcgaaagag ggtggtgaaa
    24121 aaagacttgt catagcctct tattctgaat aaacggtgtt caaaagcttg catctgcagt
    24181 aataagccca actaaacgaa aaatatgagg aactattttt gtttagctat tcttattact
    24241 tgatgcagga cagctttttc acaacctcat ttcatgtgtt tcacacgtga ggaaatttct
    24301 ttatggcggc catgtaccat cggacgagct tgcggatttc ctaaatagcc acaagtacgt
    24361 ttgactacat cacatgtttt tggatcatga tttccacatt ctggacattc gaaccctcgt
    24421 tctgtcggtt tgaaatcacc ttcgaaacca cattgatagc aatgatcgat tggcgtattc
    24481 gtaccaagat acccgatttt gtcatatgca aaatcccata cagcttctaa agctttcgga
    24541 ttttgttgga gcatagggta ttcacagtag tggatgaatc cacctgaaca atattttgga
    24601 taatccttct caaattccaa tttttcaaat ggcgttgggt ttttacgcac atcatagtgg
    24661 aaactgtttg tataatattc tttatctgtg atattttcga tgatgccgaa tttttctgta
    24721 tccaaacggc agaaacggtc agttagactt tcacttggag ttgaatagac actgaaatga
    24781 taaccatatt catcccccca tgcatctgca ttagctttta attctttgac gatatcaagt
    24841 gtgaaagctt ttgcttctgg gtttgtttcc cattcgccac cgaagaaagc tgaagcaact
    24901 tcatacaatc caatgtagcc taacgataca gtagctcgac ggtttttgaa taattcattg
    24961 acagaatcgg tacgtgaaag acgtttcccg aaagcaccat acatatataa aattggcgca
    25021 tttgctggaa tggcttcttt acaacgttct acacgataga gaagcgcatc tttcatgatt
    25081 tctaagcggt cagacagtaa ctgccagaat ttattctgat ctccttttga ttcgatcgcg
    25141 attcttggca aattcaatgt aacaacacct aaattcattc gtccgacatt tacttcttga
    25201 ccattttcgt ctttccaccc ttgcaagaat gaacgacagc ccataggtac tttgaaactt
    25261 ccagttaatt caacgatttt atcgtaattc agaatatcag gatacattct tttcgttgca
    25321 cattccaatg ctagttgttt gatgtcgtaa ttaggatctt cagggtttaa gttcacacct
    25381 tttttcaaag tgaagatcag tttagggaag atagctgtcc gcttttcact ccctaatcca
    25441 ttgattcgaa tctgtaaaat tgctttttga atttctcttt caaaccagtt ttctcctagt
    25501 ccaaatccta atgaagtgaa aggagtttgt ccatttgaag taaataaggt attgatttca
    25561 tattccaaac tttgcatagc atcgaagata tcttttttgg tttttgcttt tgcatattct
    25621 ttttggcgtt ctggcgaatc gatccattct tccgcgtctt ttagatgttt tttatagttc
    25681 aattctgcaa aaggagcaag caattcatct gttcggtcgg cagaacagcc accatattga
    25741 cttgacgcta cattggcaat aatctgtgag atttgtgctg tggcggtctg gatagatttt
    25801 ggcgattcga cttcggcatt gccgattttg aacccattgt tcagcatgcc tttgaaatca
    25861 atcaagcagc aattcgtcat cggtgtataa ggatgataat ccaaatcatg gtaatggata
    25921 tcgccttttt gatgcgcatt tgctatatgt ggtggcaaca ttttcagtcc gattgatttt
    25981 ccaacgatcc cggctgtcag atctcgctgt gtattgaaaa cattactgtc tttatttgcg
    26041 ttttcgttca cgacagtttg gtccttgttg attagctttt caatcgaaaa gttgatatct
    26101 gttgctttac tgcgagcaaa atctcgtttg gtacgataat tgatgtactc ttctgctaat
    26161 tcatattcgt ttttttctag taatatatgt tccacgatgt tttgaatctc atagattttg
    26221 acattttcag caaaccggct tttgatttct tggacaacca agtctgcaat catttgaatt
    26281 ttttcataag taagtggtga taatgagccg tgaattttct tttctgcttt gatcagtgct
    26341 tcattgatct tttgttcatc gaaatcaaca tggcggccat cgcgtttgat gactttcatc
    26401 tgggatgtct ctggctgctg agtaacgaca gttttttctt cataatttac tttcattatc
    26461 ttcaactcct gctaaattgt tcttgtctat cataaaacaa aatcggggaa ggagcaacta
    26521 aatatcggct atatatagta ttcaatgtgc tgtataattg gatttctata ctatatgtag
    26581 tgtatatttt attgtgaaaa aaggtgaaaa cttgtagctg gtggatttgt tttttgcata
    26641 tttaattttg ctgaataaaa taattgaata aaatttttta ttcagtccaa gtaaaagtga
    26701 caaaaacata agagcaaatt attcgtagat atgctactat gcaaataaat agaaatgaaa
    26761 aatgaaagag gaggagaaga attggaaaag atgatcgaag tgaaacatct aagtaaaagc
    26821 tacggcagca aactttctcc cgtcaaagcc ttagataata tctcattcac agtagaagaa
    26881 ggcgagtttg ttgggattat gggcccaagt ggtgcaggaa agacaacgct gatgaatatc
    26941 ttgtccacga tcaatttgcc tacgatgggc agtgtctcga tccaaggaaa agaaatcaca
    27001 aaaatgaaaa acagtgagct cagtgacttt cgtcgaaaaa aactaggatt catttttcaa
    27061 gagttcaatt tgatcgatac cctaaatgca aaagacaata tcctattgcc cctagcagtt
    27121 gaacggatga ctaaagagga aatggaaaag agagtaagac atgtagctca attgttgaat
    27181 atagaagaac tgctcaaacg gtatcccgat gaactttctg tcggacagag acaacgaatt
    27241 gcagctgcta gagcacttgt tgttcagcca caagtgattt ttgcagatga accaactggc
    27301 tctttggact cgaagtcggc tacagaattg ttgaactact tgaagaccat gaatcaaaaa
    27361 gaaaaagcaa cgatactgtt agtcacccat gatccatata cagcaagcta ctgcgataga
    27421 attttattta ttaaagatgg tgtgattttt tctgaagttg tcagaagagg gacaagaaga
    27481 gagttctttg agaaagtaat agacatgcag gcgacgattg gcggaggagg aaaaatgaat
    27541 gctgtataaa ctagccgtta aaagtttttt tcggcagtca cgaggctatc ttgtttattt
    27601 tttcagtttg actttatccg taatgatcta ttattccttc agcgcaatga cctacgatca
    27661 atctttagtc agaagagcaa gtcaagatac ttcgatagat ggtggattga gttttggtgg
    27721 atttatcatt actgttgttt tgcttttttt cgtattcagt gccaaccgat ttttcttgaa
    27781 tagaaggcaa aaggaaatag gcatctatca gctttttggt atgaataaac tgcagatatc
    27841 aggtatatat gtgttagaaa tcatgataat tggattgttc gcctgtattt ctgggatatt
    27901 actcggtatt attttttcca aactcttttc aatgattttg gttcgaatga tggatatgga
    27961 tcttactagt ccatttttta tctccattcc atcagtagta gatactttat ttgctttttt
    28021 catcatcctt ttagcagtat ctgtatattc aatatggaaa atatggcgct atccaatgat
    28081 tcgaagtttt ggagaaaaag aacaagcaga tagttcaaca atgcgcttca ggacaaggca
    28141 ccgattactc gcagtcatcg ggttactact tttaacgagc ggatattttg gagctagtca
    28201 ttttagggaa atcacttcat ggatgatcag ttatcattat cttgatacat tagttttctt
    28261 ttttcctttt ttaatttttt tcgtttgtgt ggtcggtact tatttgtttt tctgttatac
    28321 atttcggtta tttttgatca tattgagtaa atggaagatt tattactatg gtatcaattt
    28381 tttgataatg ggtaacacgc aagttcattt gctcaaaagt tggcgtacaa attctctgat
    28441 tacagtcatt ctcggaattt ctttaatgac aattggcggc acggctagta tctctactat
    28501 tttatcctac caggagaaag tttcctcccc gatggactat cagtttgatg ttgagacaga
    28561 gaaaaaaatc aagccgattc tagcagagga agggcagaag ataactaaag aaatcacctt
    28621 gcattataaa gtcattggga gtatctatag tcaaaatctc gaagaaccta tgtttcaaac
    28681 tgctaatctg atcacggaaa cacaatatca agccttcaga aaagttaatc cagatttgcc
    28741 gaacatttct ttgaaatcac ctggtcatac tgttttgctt gatcaaatgc aaactctttt
    28801 tcggaatatt tcattatatg gatctagtat tggactgcca gataatcaag aattgaagat
    28861 tcaacaaatg cttccaagtg tattaggtga cgaaacaatg gtatatctaa gtcctgtact
    28921 gattgtagat gataccgttt ttgaaaaagc aaaaggtgtg gattatcaag tagtcaatgt
    28981 agatgtatca ggtggaaata atgaaaaaat agatgaacga ctgagcaatg acctgtcgat
    29041 aaagtggctc aatgctgttt attattctta tgatatcgta aatggaagtc tacaaggaga
    29101 aattagcaca aagaaacttc cggatgacca aatgaaggaa gcacaattta gccaagaaag
    29161 ctctcgtttg aatttctctt ccagctattc gaaattgcgt gcagttaatc ggcgaatcgg
    29221 tatcaatatt tttgtcacac tatttgtcgg gatgatcgtg attattgcta ctggtagtat
    29281 tttgacagtc cggcaattag cagaagcaga ggaagaaaaa gaaaattatc acctattgac
    29341 taagctgggg attccacaaa gaaggatcag acggatgatc ttcgagcaaa acgcacttac
    29401 cttctttcca cccatgatat tagggatcac tcacgcagta tttgcaatca atgtcttcac
    29461 tcagtatata aaaactgccg attactggtt ggcttatctt gtgagtggct tattgatcct
    29521 tatctatctt ttgctttatg tcattacgag tcagttatat tgtcggatta tcgaggaatg
    29581 atatacggaa taagacaaga taataaatag aactaaattt tgaataccat ttatttggaa
    29641 taagaggttg tgacacgatt tttgtcacaa cctctttatt ttttatattt tttaaaagta
    29701 cgagaaatta taaagaaaaa agcagtgatt tgatgtgcta tttttataaa agctatgtga
    29761 caaaactgtt agtaaaaaaa cggtttctgt aagctagaca catgtttctt tttgtcaaaa
    29821 ttagttacac tttgtgtgag gttatatgag gagggaatcc aatgaacaaa tggcgttcta
    29881 atccaaaatt gaattattgg ggaaaattca tcattcgaac aattttttat agtgcagtac
    29941 tgctgttcct gatttatctg tatcactata aaaatattca aggaggaact tttatctata
    30001 acgaatttta ggaggaagag tatggaaatc aaaacgatta ttgaagcaat cgatgattgg
    30061 ggaataaatg aacctgatcg agttgcttat caggcggatg agacgcatac ttttggtgaa
    30121 ttgaaacaag catcagacgc acttgcttat tatttagaaa aaaaggtaga aggcgatgga
    30181 ccaattgtcg tttttggcaa tttggagttt gaaatgattg tctcatttct aggggttgtc
    30241 aaatctggcc atgcctattt gccgattgaa gagcatacac ccaaggagcg tatcctatcg
    30301 atctttcggg tggctaaacc atctatggtc atcagtatcg gggactggat agaagatatt
    30361 ccttcggttc ctgtcataac aaaaaaagaa tttcaagaaa tcaagaagat accagtagga
    30421 ttttatccca gaaatagcgt aaaaggtaca gaaaattttt atattatttt tacttctggt
    30481 actactggag aaccaaaagg cgtacaaatc agtcatgata atctagtcag ctttgttcaa
    30541 tggacgatgg aagactttgg gatcaagcct ggtatgcatt tcttagccca agcgccattt
    30601 tcttttgatt tatcggtatt ttctatttat cctgcattag tttctggcgg aatgctgaag
    30661 ccgttaaata aagcagttgt tcaagacttt cgtcaattat tcgcgacatt gccagccttg
    30721 aagttgaatg tgtgggtttc tactccatca tttatggata tttgcttgat ggaacctaca
    30781 ttcaatggag aaaatgtgcc ggaattggac atgtttttat tttgcggaga agaattgacg
    30841 aaaaaaactg cagaaagtct acttgatcga ttcccaaatg cacggatata taatacttac
    30901 ggtccaacag aagcaactgt agctatttca agtattcaga ttgaccagca tgtactagat
    30961 agttatgacc gactaccgat tggctacgta aaaaaagaca cgaaagtttc tattgtccaa
    31021 gaaggtaaac ctgtttcaaa aggagaaacg ggtgaaatca ttattgcagg accaagcgta
    31081 tcaaaaggtt acctgaacaa tcccgaaaag acagctgctg cgttcttttg tcaaaatgac
    31141 ttagcaagtt accatacagg ggatgcaggt agactagatg aatatgggct tttattttat
    31201 gaaggacgta tggatcagca ggtcaaatta catggatacc ggattgaact cggggatatc
    31261 gaacattatc tgctccaaga caaccgaatc aaacaagctg tcgtcgtacc aaaataccaa
    31321 ggaacaaaag tacagcagct ggttgctttt gtcgtattag aaaacaaaac gaaacagccg
    31381 gattttcagt tgactaaatc tatcaaagaa caattactag aagttgtaat ggattatatg
    31441 attcctcaga agttccatta tgtcgatctg ctgcctcaga cagttaatgg aaaaatcgat
    31501 cgaaaaaaat taacagctga ggtgaatcct gaatgatgtt acctcatatg atcccttatg
    31561 cagagccgtt ttattttttt cttttagcca ttgcgcttgt accgatcgtt ctatctttat
    31621 tgatatggga aaaaagatta ccagtttatc aatcagcagt gacacttttc tttttatttg
    31681 tcagctttgg aggtaattat tggcaacagg gagcggcgct gattgggtat gttttgtggc
    31741 agacgatact tgtatggggc tattttgttt atcggcaaag gaaaaatcag acaggatggt
    31801 tttttgccgc cgttatttta gcgataattc cactgttttt aacgaaagtg actccttttt
    31861 ttgaacatgg aaaagcatcg ttacttggtt ttttaggaat ctcttattta acctttaaat
    31921 ctgtacaaat gatcatggaa ataagagatg gcatgatcaa aacatataag ccatttcgtt
    31981 atatccagtt tctgctgttc tttccaacaa tctcttctgg accaatcgat cgctatagga
    32041 gatttgaaaa agatcagctc catccgcctg ttcgtgataa atatgttgat cttttgggaa
    32101 aaggcgtcca aaatattttt gtcggttttt tatataaatt cattatcggt tattattttg
    32161 gtcaagtact gcttcctgta gtgggacgca ttgccttaca gcatggtggt atttcatggg
    32221 cattagtagg ttatatgtac gtgtacagta tgtatttgtt ttttgatttt gctggctata
    32281 gcttatttgc agtcggtaca agctacatga tgggatatca gacaccaatc aatttcaata
    32341 aacctttttt atcatggaat atcaaagaat tctggaatcg ttggcatatg acgctgtcct
    32401 tttggttccg tgattatgta tatatgcgat tgatgttctt catgatgaag aaaaaatttt
    32461 ttaaaagcaa gatcgtaatg tcaaatatcg gttattttgc tttgtttctt ctaatgggta
    32521 tatggcatgg attgacgtgg tactacatcg tatatggact gtatcatgct tgtctgatct
    32581 gtctgacaga tgcatggatc cgatttaaga agaagcataa agagcagttg ccttctaaca
    32641 aatttacgca tggcttagcc gtatttttga catttcaagc agtatgtttt agcttcctga
    32701 ttttttcagg atttttagat aaactttttt ttagctaacg aatagtgaca tattaattta
    32761 tataacaaag gagaaaagga aaatggaaga acaaatttta tcaatcttag aagaaataac
    32821 aggaacagat gaagtaagaa aaaatcgtga tattgatcta tttgatgaag ggttgcttga
    32881 ttctttagca tctgttcaat tattagtcga gctagacgga gagctggata tccaagtccc
    32941 tgtatctgaa ttcgagcgag aggattggtg cacaccgaat aaaatcattc aacaagcaac
    33001 tgcattgaag ggttgagtat gaaaaagaaa ctttttgcta ttttcggccc ggttgtttta
    33061 gctgttggct tactgtttgt gttttttacc tcctcctatc aagtagatat ctctaatcca
    33121 gaaacgatta gacgtgcctc ttcttccatg tcagtgaacg tgttgaaagg agatgcgata
    33181 aaaaattatg cattatctga aaaacaatat attccttttt ttggctcaag tgaattaagc
    33241 agaatcagtc catttcatcc gtctgttctg gcagaaaaat accagcgaaa ctatcgtcca
    33301 tttttgctgg gagcacccgg gacacaatcg ttaagccaat atatgatgat gcgttctgca
    33361 ggagatgcta tgaaaaacaa gaaagtcgtc tttattattt ctcctcagtg gttcgttaaa
    33421 aatggtgtaa aaactgatta ctttaatacg tattattctg aacttcaaac atacgactgg
    33481 ttgttttcaa tgaagaaagt aacgcctgct gatcgctatt tagctagaag attattaact
    33541 ttctcaaaag taaaagagaa tgatacgttg acggcgattc tgcaaacgat caaaaaaggg
    33601 aagctacctt tacctgaatc tttgaatcag ctgcgcagcc aatggaacat gctgaagaga
    33661 gaggatgaag tattcagcaa tattgggttg aaagatcgac agcaaaaaat cgatcatgag
    33721 tcaaaacgat taccaaaaca ataccaagaa acagaattat ccattttagc aaatcaaatt
    33781 ggagaacgag aaacgacgaa taatccattc gggttgaaaa acgattttta tacgcatcgt
    33841 atccgagccc acgagccaga gctcaaacag tcacaaaaaa attgggatta tcgtttttcg
    33901 ccagaatttt ctgattttca gctggtcttg gatcaattag caaaaaacca taacgaagta
    33961 ttgttcatca tcccaccggt taacgagaaa tggagcgatt ataccggact atctcaagaa
    34021 atgttacaag gatttgccaa aaagatcaaa tttcaattaa atagccaagg attcaatcga
    34081 atagctgatt ttgtcaatca agcgggtacc aactatttta tggaagacac gatccatcta
    34141 ggctggaaag gctggttggc tgcagatcaa cagatcagac cgtttttaga agaaaatcat
    34201 attactgcta gtaagtatca tcttgacgat gcttttttta gcaaatcttg gcaacatcaa
    34261 ataccagata aactacaatt aaaataaaga aaacaggcga gtgttgctcg cttgttttct
    34321 ttatttttga atattctgaa taaaagataa aaataccaag tttgcctgaa caaaaatcat
    34381 aagcaatggt ataatcacaa tatgaatata gaaatggggg aaaacatttg gatacaaaag
    34441 aagaacagct acttattgat ttaacttctg caaaaggagt acctggaaat gaagaagagg
    34501 taagagaagt attcagagaa tatgccaaac cattcgctga tgatattttt tatgacggtt
    34561 taggcagtgt gattgccaaa catggtgctg gcggaggccc caaggtcttt atttctggac
    34621 atatggacga agttggtttt atggtaacaa aaataaccga aaaaggattc ttggaattcc
    34681 aaactcttgg aggttggtgg gggcaagtca tgcttgctca gcaagttgaa atcaaaacac
    34741 gtgaagggaa aatcgtccac ggtgtgattg gttccaaacc accacatgtt ttaacacctc
    34801 aagtaagaaa taaaccttat gaaataaagg atatgttcat tgatattggc gcatcaagcc
    34861 aagaagaagc caaagagtgg ggcatacgtc ctggagatat ggtcactcca tatattgaat
    34921 acaaacgaat gaatggcagt aaatatttac tggcaaaagc atgggataat cgtatcggga
    34981 cagctgtttc tctgcgagta ttagagaatc tatctaaaga agcacaccca aatgttttat
    35041 tcgcaggaag cgatgtgcaa gaagaagtag gcttgcgagg tgctcgaaca agtacacacc
    35101 ttgtaaatcc cgatattgct tttgctttag atactggtac agcaggagac actccaggaa
    35161 tgacaccaaa agaagcagat tcgattttag gaaaaggccc acagattttg atttttgatg
    35221 catctatgat cccgcataaa aaattattga attttgttat tgatgtagca gaggaaatgg
    35281 atattccatt ccaatataca gtgatttctg gcggaggaac tgatgcagga caaatgcatt
    35341 tgacaagaga tggtgttccg tctgtagcca ttaccgttcc tgttcgttat ctgcattccc
    35401 atacatcagt gattcatgaa gatgattatt tgaatacagt gaaactagtc acagaattag
    35461 tgaaacggct tgatagtgaa acagttgaaa aaattcggag ttatgaataa tgaataatag
    35521 aatacctatt tctgaatatc ggaaaaaagc acgagtttct ttggaaaatc aatggggaat
    35581 caatacttgg cttgttttct tatctataat atttacgagc gtcatccaga acttttttga
    35641 cggtttcagt ccttttccgg aagaaagcat gcagcagcac ttattgagtt ttctagtcga
    35701 taatttactt ttattcgcat tcaactatgc attgttttac attgcgctag tagttgtacg
    35761 gggtggcaga ccaaaaagta accttttatt ttcagttttc caaagaaagt attttggttc
    35821 gatacttggc atcaatttga tcaattcagt catcaactgg ctactcaaca gtttaatctt
    35881 tctgcccatg tttttaatca gcggagtgag tacttatatg cagctgcttt tcagttcaaa
    35941 tgcggtacct acgggtgtca tgccagaaga ttttcttgat atcagctttg ttttatcgat
    36001 gatagggatg atttttgttt cagcactcat catgagtatt gttggcggtt tattccaatt
    36061 tgctgcatgg acaaagttcg actatcctga tttgtcggtt attcaatgtt tgaaatatgg
    36121 ctggttttta ttgaaagata gaattggtac gtatattttg ttgcagctgt cttttatcgg
    36181 ctggtatttg ctaggagcaa tcgctttgtt catcggtctt ttgtgggtca ttgtttatgt
    36241 gaatgtgtca gttgcagaat tttatgaaca agcacggatt gaaaaaggag gtccagacgc
    36301 ctattttact tagcatgtaa gcagtttatt catcaaaaaa ataacttttg tggtaggata
    36361 aatctttgag ggggaatgta cgatgaaatt aactgtttta ggatgcttag gagcgtatcc
    36421 ttataaaaat caagggacaa caggttattt gcttcaatct gacgggttca atttgttgat
    36481 cgatgcaggt agtgctacgc tgatcaaatt acaagaacac cttgatccac ttgatctaga
    36541 tgctgtgatc cttagccatt atcatcatga tcatattgct gaccttggtg tattacagta
    36601 ttactggcaa cttcatccta agagaaatcc ggagacattg ctttcaattt atggacacac
    36661 aaaagattcc attcactttg aagaattgac gttggaaaat gtctcaaaag gacatcctta
    36721 ttttgaagct gaagaattaa aaattggtcc ttttctgatt acttttatgg aaacaatcca
    36781 tccagtagta tgttacgcca tgcgtatcgt agaagaaaca acggggaaag tattcgtatt
    36841 tacaggtgat tcaggttatt tggaaagttt cgctgatttt gcgaaagatg ctgatttgtt
    36901 tctagcagat acctatcttt ttgaaggaaa tgaacatcat catgcccatt tcacttcaaa
    36961 agaagctgga gaacttgcga aatcagctaa cgtaaagaaa cttgtactta cacacctacc
    37021 tcagtttggt gatttagaac aattgaaaaa tgaagcgcaa aaggcagcag gcaaagggat
    37081 tgatatagaa cttgctgcag ttgacaaagt gtttaacatt taggaggaag aacatgattt
    37141 ttgtaccaaa tgaaaaccac gacccaagaa tcaatttagc aattgaacaa tatttgctgc
    37201 aagaaatgcc tttagatgaa cctattttgc tcttttatat caatgaacct tcaatcatca
    37261 tcggcagaaa ccaaaatacg cttgaagaaa tcaatcgaga ttatgtggaa gaaaatggca
    37321 ttcatgttgt ccgtcgctta agtggaggcg gagctgtcta ccatgatttt ggaaacctga
    37381 actttagttt tatcatgcct gatgatgggg attcattccg tgactttgcg aaagtaacac
    37441 agccaatcat ccaagcactt catgaattgg gtgttgctgg ggcggaattg aaaggccgaa
    37501 atgatctagt cattgatggc atgaaatttt ctggcaacgc gatgtatgct accaacggtc
    37561 ggatgtttgc tcatggaaca attatgttcg actctgatat caatgaagta gtcaatgcat
    37621 taaaagtaaa aaaagacaaa atcgaatcaa aaggaatcaa atcgatccgt tctcgtgtaa
    37681 cgaatatcaa accatttctt ccagaagaaa agcaaaaaat gacaacagaa gaatttcgtc
    37741 aagaaatctt gttgaaaatt ttcggcgtag agtcagtaga agaagtaaaa acgtacgaat
    37801 tgactgatga agattggaaa aaaatcaatc gaatctctga ggaatattat cgaaattggg
    37861 attggaatta cgggaagtct ccagatttca atttctctcg ccaaaaacgt ttttctatcg
    37921 gttcgattga agtccatttg aatgtctcag aaggaatgat caaagaagca aaaatctttg
    37981 gcgatttctt cggactagga gatatctctg acgtggaaaa aaaattggtt ggacagaaat
    38041 atgataaagc atctctatca aaaatagtca gccaaattga tgtgaagaaa tattttggtg
    38101 cgatagaacc agaagaattg cttaccttac tttattgaaa ataaaaaata gcggaatcca
    38161 catatatgga ttccgctatt ttttatacag gattcgggta atttcgagag agttgaacag
    38221 tgatccgatc aatgaaagta tctttttcct gcgttagtgt tcctgtgtaa cgatccgcta
    38281 cgtctttcat catcattaag tcaaaacgtt cctgatcatc taattcttct gtgatgcctc
    38341 gactaaatag gtttgtatcg taatgtgcac tatgttcgca acaaatgacg aaatgttcct
    38401 cttgttcgtg tatcgacaaa taaatttttc gatacagtgg attttcgatg gcatgagttt
    38461 ctctaaagga atgctctaaa gcgtggatca aaagttgagc cagatcgtca tcgttgatag
    38521 gaagttcttc gggaagatct gcttggaagg ttatctgaat attccgtttg gcagctaact
    38581 tctggtaacg cgctaagata agatttgtca cctggtggtt gcaaaaagaa cacagcattt
    38641 cgaaattttt tgcttcttct aatatctttt ccacatagtt tttagctttt gtttggtccg
    38701 tatgcattaa atcttgcaga ttctccatct cttggacaaa ttccaggcga agtgtattta
    38761 cttcttggat atgctgtcga agctgctcat aatgttgctc caacaaatca tttttgattt
    38821 ttaagaaatc tacttgtctc cgatctttgt cggtatttaa gatgtgatcg attagattgt
    38881 agctgataat aacgattaga atgataatat ataaaatcgt agaccaattg atcgttgttt
    38941 gatagatacc taatgccgtt tggatgtaaa tcaagcaatg gataatggct accaagacga
    39001 tccaaggtgt acaagctaca taaaaacggt tattcttata tgcttcgcca atgcatgcaa
    39061 gtgaagtgac taaagtgctt ataacactag caatattagc aatcggcatt aattcaggaa
    39121 gttctgcagg agtaaaagtt gcataaagca gaacgccgat aaaaatcaaa agttggaacg
    39181 tacaaaaaat tccgtaccat tttttatagt aaaacattcg gctccaatag tagcagatga
    39241 tgaaagctga cgttaagata ataaataaat gagataaaaa agaatgaacg aatggttcaa
    39301 aaagaatacc acttaaaata tcttctgata cagcttcaaa tcctaatgcc aaagcaaagc
    39361 aacttaagag aataagtgag tattcaagac gtttttgttt atacatcaag tagatcgtat
    39421 agaaaaaggt ccctatagcg ataaaaacag cgattatcat cgtcaatact tgcggcactg
    39481 attgtgaata aataaaacta atcaatggtc cagttgttcc tagataaact ttcggtggca
    39541 gtccagcata gttctgataa ggagatgaga ctgtaagggt caattttttt ccgatataat
    39601 ttgctggtaa atctatcaca gccaatgaga gtccgggatt gctttcttcc tgataatctt
    39661 tccgttggta taaaatcttt tcgcctagat atacagtaat ccattgatgg tttcctttga
    39721 ttagtaaatt tgcttcgtcc aacggttttt caagtgtcgt ttccataatg aatgtttcgt
    39781 ctttatccac ggtaggaatc gtacgagtgt acttgctgtc aaacttaaaa tcaggatcat
    39841 cttttgtata gaaaacccac gaatctttta tttctttcat ttgattgctg tccgcaggag
    39901 aaaaaataaa ataaaagaaa taagcaattc
//
LOCUS       DAFLVO010000020        38454 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.020, whole genome shotgun sequence.
ACCESSION   DAFLVO010000020 DAFLVO010000000
VERSION     DAFLVO010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38454
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.020"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            364..684
                     /locus_tag="L1U99_001079"
     CDS             364..684
                     /locus_tag="L1U99_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBN1211635.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            838..1743
                     /locus_tag="L1U99_001080"
     CDS             838..1743
                     /locus_tag="L1U99_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1211636.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            1740..2513
                     /locus_tag="L1U99_001081"
     CDS             1740..2513
                     /locus_tag="L1U99_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBN1211637.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(2694..4118)
                     /locus_tag="L1U99_001082"
     CDS             complement(2694..4118)
                     /locus_tag="L1U99_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1211638.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            4329..4775
                     /gene="nrdI"
                     /locus_tag="L1U99_001083"
     CDS             4329..4775
                     /gene="nrdI"
                     /locus_tag="L1U99_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBN1211639.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(4840..6822)
                     /locus_tag="L1U99_001084"
     CDS             complement(4840..6822)
                     /locus_tag="L1U99_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1211640.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(6836..7732)
                     /gene="murQ"
                     /locus_tag="L1U99_001085"
     CDS             complement(6836..7732)
                     /gene="murQ"
                     /locus_tag="L1U99_001085"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBN1211641.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(7735..8796)
                     /locus_tag="L1U99_001086"
     CDS             complement(7735..8796)
                     /locus_tag="L1U99_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBN1211642.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(9007..9573)
                     /locus_tag="L1U99_001087"
     CDS             complement(9007..9573)
                     /locus_tag="L1U99_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBN1211643.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(9601..11103)
                     /gene="eat(A)"
                     /locus_tag="L1U99_001088"
     CDS             complement(9601..11103)
                     /gene="eat(A)"
                     /locus_tag="L1U99_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBN1211644.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(11361..12482)
                     /locus_tag="L1U99_001089"
     CDS             complement(11361..12482)
                     /locus_tag="L1U99_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBN1211645.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            12608..13549
                     /locus_tag="L1U99_001090"
     CDS             12608..13549
                     /locus_tag="L1U99_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBN1211646.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(13699..14595)
                     /locus_tag="L1U99_001091"
     CDS             complement(13699..14595)
                     /locus_tag="L1U99_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBN1211647.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            14864..16204
                     /locus_tag="L1U99_001092"
     CDS             14864..16204
                     /locus_tag="L1U99_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1211648.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            16422..16865
                     /locus_tag="L1U99_001093"
     CDS             16422..16865
                     /locus_tag="L1U99_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBN1211649.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(17369..18787)
                     /gene="nhaC"
                     /locus_tag="L1U99_001094"
     CDS             complement(17369..18787)
                     /gene="nhaC"
                     /locus_tag="L1U99_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBN1211650.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(19190..20413)
                     /locus_tag="L1U99_001095"
     CDS             complement(19190..20413)
                     /locus_tag="L1U99_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBN1211651.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(20444..21283)
                     /locus_tag="L1U99_001096"
     CDS             complement(20444..21283)
                     /locus_tag="L1U99_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBN1211652.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(21300..21980)
                     /locus_tag="L1U99_001097"
     CDS             complement(21300..21980)
                     /locus_tag="L1U99_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1211653.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(21982..23055)
                     /locus_tag="L1U99_001098"
     CDS             complement(21982..23055)
                     /locus_tag="L1U99_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1211654.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(23111..23349)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(23392..23625)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(23702..24373)
                     /locus_tag="L1U99_001099"
     CDS             complement(23702..24373)
                     /locus_tag="L1U99_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBN1211655.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(24460..27138)
                     /gene="mgtA"
                     /locus_tag="L1U99_001100"
     CDS             complement(24460..27138)
                     /gene="mgtA"
                     /locus_tag="L1U99_001100"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBN1211656.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            27797..28234
                     /gene="ndk"
                     /locus_tag="L1U99_001101"
     CDS             27797..28234
                     /gene="ndk"
                     /locus_tag="L1U99_001101"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HBN1211657.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(28256..29122)
                     /locus_tag="L1U99_001102"
     CDS             complement(28256..29122)
                     /locus_tag="L1U99_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBN1211658.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLSHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(29282..31375)
                     /locus_tag="L1U99_001103"
     CDS             complement(29282..31375)
                     /locus_tag="L1U99_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBN1211659.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(32124..32747)
                     /locus_tag="L1U99_001104"
     CDS             complement(32124..32747)
                     /locus_tag="L1U99_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211660.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(32906..34303)
                     /locus_tag="L1U99_001105"
     CDS             complement(32906..34303)
                     /locus_tag="L1U99_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1211661.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(34335..35306)
                     /locus_tag="L1U99_001106"
     CDS             complement(34335..35306)
                     /locus_tag="L1U99_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1211662.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            35680..36105
                     /locus_tag="L1U99_001107"
     CDS             35680..36105
                     /locus_tag="L1U99_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211663.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(36593..37294)
                     /locus_tag="L1U99_001108"
     CDS             complement(36593..37294)
                     /locus_tag="L1U99_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBN1211664.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(37310..37750)
                     /locus_tag="L1U99_001109"
     CDS             complement(37310..37750)
                     /locus_tag="L1U99_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBN1211665.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(37750..38325)
                     /locus_tag="L1U99_001110"
     CDS             complement(37750..38325)
                     /locus_tag="L1U99_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HBN1211666.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
BASE COUNT        11119 a         8015 c         6696 g        12624 t
ORIGIN      
        1 ttttttatca caaaaattat cttacttatt gtaaggtaaa gcttttttta atttattgcc
       61 cgataatata tagaaataag gtctagttac tgtttttttt aaatgattaa taaataacaa
      121 cttctttcta tgaaattgca aagcattcat cttcttttcc gctaacgata tatccgtcag
      181 tgcttggtac actttactaa aaagtatgag attgccgata tctggatagg tgtgctatac
      241 tacagaaaaa gatatacaat ctgccaccgg gtaggataaa gaggatgatc attccattag
      301 gtctttgaag ggatgatttt cctctttttg tgtatttttt tatagttaag gaggaatgta
      361 agtatggcat ggatggaatt aatcatagca ggaattttgg aagtattctg gtcaacgatg
      421 atgaaatgga gtgatggttt ttctaaaatc aattattctt tttacacagt gattggcatg
      481 attgctagtt tttacttttt gtcaaaggca atcaaaagtt tgccgatgag tctctcttat
      541 cctatctgga cagggattgg cgcagttggt tcggtcataa ttggtgtggt cttgtttcat
      601 gataagctga atctttccac ttggttcttt gtggggatgc tactcatcag tatcattggc
      661 atcaagatta ctagcggcca ctagacactt ggaataagta ctgatcagaa aaaataagcc
      721 tttttattta atattcaatt tttttatgaa aaaataagaa ataagtccaa tgacctagcg
      781 acttctccac tcatcaggtg tatgcttgta ctatctatag aaaaggagtg aatatttttg
      841 aaaagtcttt cggtccaaga attatccaag aactttggtc acaaacaagc cctcagcgat
      901 gtcagtttta gcttatcccc tggcaaaatc gttggattag taggtcctaa tggcgctgga
      961 aaaacaacga tcatgaaagc tattttagga ctgatccatt actcagatgg aacaatctgt
     1021 attggtgaaa atgagatttc tccctctagt cataaagggt tggaacaagt aggagcattg
     1081 atcgaatacc cgggtatcta tccattctta acaggctatg atcatctgaa gttattctct
     1141 gaaaccaacg atgtatctgc tatcgacact atcgtgaatc agctcaagat ggaaaagtac
     1201 attcacaaaa aagcgaaatc ctactcgttg ggaatgaaac aaaaattggg aattgctctt
     1261 gccttactga accatccgtc tatcgttatt ttagatgagc cgatgaacgg tttggatcca
     1321 caagcaacaa gagatgtgcg aaaaatcatt accgacttgg ctactcaggg cacctctttc
     1381 ttgatctcca gtcacttact cagcgagctt gaaaaaatgg tcgatgagct gatcctgatc
     1441 aatcaaggaa agatcatcaa acaatgtaca atggctgaat tgaaccaaac agcgcaagat
     1501 ttcatcgtta tctctacaac aaatgatcta gctgctcgaa cgatcttgac agaagctgga
     1561 tatactttgg aagatcctga taaaatcaag cttttaaaag aaaacgaaga attattagga
     1621 accgtgatcc agctattgtc tgcacaaaat atccatgtga cagacgtcca gcatctgacg
     1681 aatgatttgg aatcttctct attggaaatt ctggattcag taaaggggga agaagaaaaa
     1741 tgacattgct tgtaaaacaa gaattattta aattgatcaa gaaaaagtca actgctgttt
     1801 tatctgttct attagttgtt ttgctcatag gaacagcact tctagccaaa aaatacacga
     1861 cgatcattga tccagttgaa atgactgctc agctttttag tgccacatct tggattgtct
     1921 ttatcatgat tgcagctgca agcacgatca tttcgatgga agcacaatat ggtacattga
     1981 aaaatctcct ttatcgaaag tattctcgag gagaaatatt agtaagcaaa tggatcacat
     2041 tagttattta ttctgtttat ttataccttt tagctattat tgtcactgtg ttgatgaaac
     2101 tgattctttt cccttcgatt tccttcacgg agaaggtttc tactggtcaa acactgatcc
     2161 aaagcttgtt cacttatact ttgggtagtt atatcggttt atggctgatt ttaagtttag
     2221 tgttgatgat tgcttgcttt atcaatagtt ccggcgcatc catctcagca ggaatcgtct
     2281 tttattttgc ttcgtcaatc atatctggta tccttattgc actcatccaa aaatgggagt
     2341 ggatcaaatg gaatccgatc agtatgttga atctgcaaaa ccaaattgga aacgaagaga
     2401 tcatgaagca attgactcat ctttctacta atcaaatgct attcggtaat ttagcttaca
     2461 tcgttttgtt cttagcatta ggatatctcg tatttaagcg aaaaaatgta tgatgactca
     2521 tcaaaaaaga ggctgtgaaa gagacgttca gccttattgc cgattggctg tctcttaaac
     2581 accgtttatt ctgaaaaagg agctgtgaca acatttgtgt cacagctcct ttcctagtat
     2641 gtttttgaat aaacgacagg ctcacaacct ctctttatac ttcttttata cttctatacg
     2701 tgaagcatcc cagtggcaaa taaaaccatt gcaatcactc cgaccatcgt cacacctata
     2761 agtaaaatct tatctaagtg gatatgttgt acaggctcgt tttgctcctt acgtgctttg
     2821 aggtaaaaat aaatgcctgg caagaaaaga acaagaacaa gcattacttc attaaaggct
     2881 acgactagca tagcccatac ttgaaaggca cttgctaaaa gccctactaa aaattggacc
     2941 cattctttcc gctgataaga aagtttcatt tggtacaatc ctaagaaaag ccacgtgaag
     3001 aaaatagctg ctgtaccaag tgtgtaagca aagttataag cactgtcagt gaataataat
     3061 gaaagtaaaa agacattcgt acataacgtc gtcaatacga tagcataagt tggtgcccca
     3121 tttttgttga gttttcccca tgctttaggc aaaagtccgt cttcagccat gtttcccatt
     3181 gtttcaatcg gtaagatcgt ccatgagagc caaacaccaa ctaaagaaat gatcaaaccg
     3241 ccgttgatca cgactgctcc ccatttacca accatcattt caaacacata gcccatagca
     3301 ggctgcgcct tgatcgtttg cagctgattc atcgtcattg tcccatatgg aagcatggaa
     3361 accaagacgt aaataataat caagccgaat atccctagaa tcgttgcttt cccaacatct
     3421 gattgttttt ttgctcgtga acctacgaca gaggctcctt caataccaac aaatacccaa
     3481 agcatcacca tgatgcaact caatacttga ctggaaaacg ggatcggctg tccattcgca
     3541 ttcaatataa tgtcgctaga aaagttatca atgaattgtt ggatcgaaaa cgtgctgata
     3601 gctactacaa taaataaaaa taatggcact aatttacaga atgtgacgat agcattgacg
     3661 aaactagcat tttcgactcc ccgattcact agccatgcat atccccataa aaagactgta
     3721 ctcatcacga tcgatgccag attttgccca ccttcaaata ctgggaagaa atatcctaat
     3781 gcgctcatca acaatgttgc aaaagctacg ttgcctaacc agcatgtgag ccagtaaccc
     3841 caaccgctga taaaaccagc gaaacggcca aaaccttctt ctgcgtaact aaagatcccg
     3901 ccttttaaat ctggacgttt tttattgata ttattgatcg acaaggagag catcaacatt
     3961 gctgttccta cgagtaccca actgaaaata gctgggccgc cagccgatcc ggagatgtcc
     4021 gtcataatac caaatacgcc acctccaatc gctgaaccaa ttactaaggc agcaagtgga
     4081 attaaaccaa ttcctttttt ctgttgctct gtatccatgt aagcatcctc caaaataaaa
     4141 ccgcttttat caaaaagtat aacaaacctt ttttattttt acttaattaa taaaaacttt
     4201 aatagaaata taattctacc ggcttttttc tcattataca agcaaagcgc ctagtccctt
     4261 tccaaattac accaccaaaa aacttaaaaa agatgctata ctaaaaggaa agaattggag
     4321 gatgatccat gaacatttta tatatatcga tttcaggaaa tacgcgtgcc tttgccaaac
     4381 atctagcaga atatgctgaa aaaatgcatg cagaagatcc tgtcaatcct gaagttactt
     4441 taaaagaaat ccatgaaaat agtgatttta cgaaagaaac agaaccattt tttactttcg
     4501 ttcctactta tttagacggc ggaaatggtt tagataacgg tgatacagaa atcttgaccg
     4561 aaacgatgcg tgaatatctg gaacatgaag acaatcataa actttgtctt ggtgtagtcg
     4621 gtagcggaaa taaaaacttc aataatcagt attgtctaac agccaaacaa tatgcacaaa
     4681 catttggctt tcctttcttg gcagattatg aattacgggg aacaccatct gatgtgacac
     4741 gaatttatca gattttagca gaaaacaata aataataaaa aagaagaagc tgaaaaatag
     4801 atttcagttt cttctttcgt ttctattgtt tctatcatat taagctttga catccatcac
     4861 aggtgctttt gcttttgctt tacctgtttt ttccaagaca aagtttttta cacgatccat
     4921 attggttacc aagacgatca tggatgtttc tttgcctgct gctttgatcg cttctaagtc
     4981 agcttctgct acaagcgtat caggtgtcac ttgctgccct tctgttactt tcacatcaaa
     5041 tggcgtaccg cctaagtcaa ctgtgttgat tcccatatga agcaagattt ctaaaccatt
     5101 tggcgttgtg atcccaatag cgtgtttcgt tgggaagaca gagctgacta ccccagtaac
     5161 tggagaatag atatgtccgt tttctggttc tacaaagtag ccttcaccca tcatcttttg
     5221 tgcaaaaact ggatcacttg ctttatctaa agaaacaact gttccgtcag caactgatga
     5281 gaggatagtc acactttcag ctgaagtttg aggtactact ttttcaggca cttcatttac
     5341 tgtggctgtt tcagtcgcta attcttcttt ttctaaacgg tctttaggaa taccgaagaa
     5401 gaatgtagca acgaagccac cagcataagc tgccaataat ccaaggatgt agcctaacca
     5461 tttaccgtca gagatcaatg ggatcaaagc ggctcctgaa ggtccaatag cgatagcccc
     5521 gacatttccg atcattccga tcactgcccc gccgatacct ccaccgatac aagcagtaat
     5581 aaatgggcgt cctagaggta atgttactcc gtaaatcaat ggttcgccga ttcctaggat
     5641 cccgactggt aaagctcctt tgatcatttc tgttaattct ttatcttttt tgcagcgaat
     5701 ccataatgcc aatgctgcac ccacttgtcc tgcaccagcc atcgcaagaa ttggaagcaa
     5761 tagcgtacga ccagtttcat caatcatttg cacatggatt ggagtcaaaa tttgatgcag
     5821 tccgaacata accatcggca agaataatgt gcctagaacg aagccggcaa atgctccacc
     5881 aacgccaagt acccagttga tcccaccgac catgccatca gaaatgaaac ctgctaaagg
     5941 catgatgaag aaaatttcaa tcagaccgat ggcaatcaat gaaagagttg gtgtaacgat
     6001 gatatctacc gcatcaggta ctactttatg cagttttttc tcaacgattg acaatagcca
     6061 aacagcgaag atgacaccta ggatcccacc ttgtccagct gcaagagctt caccagtaaa
     6121 taagtttttc agtggtgctt ccggattcat ccctgtcagc atcacaacgg ccccgataac
     6181 tccaccaaga gttggtgttg caccaaaaac ttgtgcagca ttgatacctg tatagataac
     6241 taggtagcta aacatcccgt ttttcaagat gttcatcaca tcgatatatt gttgccatgt
     6301 tgctgcatca agtgttccgg ctgtgactaa gtttgctaaa actgcggcaa tccctgccac
     6361 gatcccagta ccgacaaatg caggaatcat tggcacaaag atattagaaa tgtcttttaa
     6421 taccgatttg attttagatg gtttttgttt cgatttttgt gccgctttca tttcttgtgc
     6481 ccgttcgttt acacggtctt ttccagatgc tgatgaattt gctgtagctg tacttacaga
     6541 agaaagtttt tctcctaatt tcacgcctgc caaatcaacc atttgctgtg ctactttgtt
     6601 cactttccca ggtccgatga tgacttgaag ctgttcatct tctactacac caagcactcc
     6661 tggaatcgct tttaattcag agacatttac aagatcatca ttgatgatct tcatacgcac
     6721 acgagtcatg cagtggacaa tgctttctac attgcccatg ccgcctgccc ctttataaat
     6781 ttgttttgcc agttcttcca aagtcagttc gttttttgcc atggtctttt ccccctcata
     6841 aggtcccttt tacaaatccg tttgcttcag ctaattttgc ttgagcttcc tctttatcac
     6901 tatttgtcaa aatcatgacg atagccagct taacattttg atctgcttct tcaaagtact
     6961 tttcagctgt ttcgtaatca gcttctgtcg cttgcatgat gattcgtttt gagcgttcga
     7021 ttagtttttc atttgttggt ttgacatcga ccatcaagtt attgaatact ttacctatac
     7081 caatcatact gatagtagaa atcatattca agataagttt ttgtgctgtt cctgacttca
     7141 atcgagtaga gcctgtcaaa aattctggac ctgcatcgac ttcgattggg aaatccgcgt
     7201 gtttactgat ttcggcttgt ttattgcaag aaatcgttcc tgtgacagca ccgatcgatt
     7261 ttgcgtaatc taatccaccg atcacatatg gtgtacgacc gctagctgcg ataccaataa
     7321 ctatatcatt ttttgtcaaa ttcagcttga ttagatcttc ttgccctagc tcataagaat
     7381 cttcggcccc ttcgacagct acagtcattg cttcttctcc accagcaatt agacctatga
     7441 ccatttccgg ttctacaccg aatgtcggta cgcattcagc agcatctaac acacctagtc
     7501 ttccacttgt tccggctccc atataaatca gacgtccacc ttttttaaag gactcaatcg
     7561 tgttagcaat cactggttcg atacttgtca gttctttttc aaccgcagcg gccactttct
     7621 gatcttcttt gttcattagt tgaacggctt gagaaatact catctcatct aatccaaaag
     7681 tttcttggtt tctgcgttcc gttgttaggt tctctaaatt gattttgctc atttttatct
     7741 tccttctttt cttataaatt gatagttcat accagctttg atttggttga tcaatggtag
     7801 ctcttctttg ataactttag ctactacatt cactttttca tccgctggca aatcatattt
     7861 ggttaattgg atctcaccca tatagcgcaa atacttttcg ttatctaaag taatagaccc
     7921 tttcatacgc gtagctgtat ttcttgctgg gataggcgga atctctcgaa aacgtgcatc
     7981 tacgcttcgt atgacatctc ttgcatcgtc ttgccgattc gtatgcttcc ctaatatata
     8041 ttcgtaaaat tcttcatcta caggttccgt atggagcaag actgtctgtt ctttttggaa
     8101 agaagcaaat tgctcctgaa cgttttctga cagacctgca tctccgatgt aaacaatatc
     8161 cgtgttactt gctaatagat ctagagcgcc tgcaagagga tggatccctc gatgttcttc
     8221 caaagttggc aatccttgat atagtgggcc tctcaactct gtatctcctg gtacaaaacc
     8281 ttggacaagg agaccttgaa ttttgagcca ttgatttttt ttctgatacc attctttgtc
     8341 cagccctgtt tcgggacgtg gataataatt atgccaagct tcaatctgtg agaaatcagc
     8401 ttctgcttct ttcaattcat cgatatcttt aggcgtgatc gtgctagcat tcaaactgat
     8461 tttcaattga tgtgaccagt cggcaatctg ctgattggaa atatgataat ccattcttaa
     8521 acctgttaca ccaattgctt tcaaaggcgt tagatcttct aatgaaaaac ccgctcgttc
     8581 caatgcctct cctgaaatat cgaccatcaa ttctagttta ttctttttcg cttcgcttcc
     8641 tagttcgatc aatcgctttt gatatgccga aacatcatct tctggtatat gcatggaagt
     8701 gaaaataccg acaaagccat tggatgccat ttggcggata tactgtttct tctcttctga
     8761 caaagaatcg ttcataaata ttgaaaagcc aaacatatta tccctctttt tctgtatccg
     8821 tcttcatttc tatgactaga gtatatatct aaagaaacaa aatttcaata cttttattaa
     8881 aataattaaa tttcatttct aaaggttgag tttatattat caaaagaatt gtcataacct
     8941 aaaaaaggca ctgctaagca aaagcagtgc cttgaaatat tttatttaaa taacacaaaa
     9001 acataattac tcataagaaa ccaattctgt attatctacc atgaatgtaa agaacccctc
     9061 attaggcatc ggatgaaaat aagcattgat cactcttatc aaggcattat ggcaaactaa
     9121 cagatagaca ttttcttcgt cttcgatgca ttctttcaat aaaggaacga tccgtgcata
     9181 cacatctaag actgactccc catttgggaa tcgtacagcg aacgctaaac gtgctttttg
     9241 aaagttctca tctttgcttg gcagtccatc ataatcccca aaatccattt ctaccaatcg
     9301 ttcatcaacg gtcagcggca agctgagacg atcagcaact gcttgtgctg tatctcttgc
     9361 tcgttgaaga ggggaatgga tgattttcgt gattggaaca ggcaaatcta ctaccttttc
     9421 tgctagtttc tgtgcctgca tctgtccttt ttcagtcagc ggcacatctg cccgtccgca
     9481 aactaatcct tgtgcgttcc aagttgtttc tccgtgtctc gttacataaa gcatgtgatt
     9541 ctctccttcg ttggcaaagt tccccttaac cataccttgt tgttcttgag attacaaggg
     9601 ttagattctc tcaagagaaa taatctcagt agatacttta tccaggaagg tttgatcatg
     9661 ttccactagt aacatggcag gtttcacgtt caagatcagt tgttctaatt gttcttgatt
     9721 gaagacatcc aaataattca atggttcatc ccatgtatat agttcagctg gctgtgataa
     9781 agatttagcc aattccactt ttttccgttg gcccatactc atctgctcga tcttgttatg
     9841 aaaaacatct ctttccatcc caagctttcg gaggttgttc aaaaatgctt ggtagtctac
     9901 ttggtttttc tctgcaaatt ccgccaacgt tcctcgattg tcttcataat tttggcttgc
     9961 ataactaatg ctcagatgtt ttggctggta tttttctcct ataaccttgc cgttgaatgc
    10021 ccccagaaga taatggataa tggatgactt tcctgcaccg ttaggacctg aaatcgccac
    10081 ccgctgatga ggctcgattg taaaatgaat tggctcgaat aacagatttt cataccctaa
    10141 ttgaagatct tctacgctta aaagtcgctt atggtgagac gcttggctat tcatcgtcaa
    10201 agaatcgata tattcgatat cttttaatag tttttctttc tcgctgatct gggtctccat
    10261 ccgattcacg attgctttgg atcgtttcat cgtccgtgca gcatcagcac ccactgctcc
    10321 tttattcact cgtctagatt cagtatcgat gaatccgact tgtttctttg ttttatctcc
    10381 ttctcgggaa cgagaccatt cggctttttc agctgctgtt ttctttagcc tactgacttc
    10441 ttttttcaat ttttcatttt gagccatttc aaattcatca cgaagttttt tctgttcttc
    10501 atagatagag aaattccctt gataaagttc cagttgactt ttttcgattg ctaaaacatg
    10561 gtccactact tcatcgataa atccccggtc atggctgacc acgatgaagc cttgtttttt
    10621 ctttttcaaa taagccgcta cttgttttct accagagata tccaaatgat tcgttggttc
    10681 atcgattaac gggaaatgag tgtcatccac aaataaaagt gccagtagga cttttgtctt
    10741 ctctcccccc gatagtgtgc tgaattctct ccataagatt tcaggatctg tttgcatcaa
    10801 ttggagctct ctttcgattt cccatatctc aaaatccgta atatcattta acacgtaata
    10861 ggttaaacgt tctttatctt ttgtctgttg cgggaaatag gcaaattctt gctgatggat
    10921 tacttgccct tgataaggta gtttgttttg tagaatattc agtaaagttg tctttcctcg
    10981 accgtttcgt ccgataagtc ctagtttcca ttgtgtgtca aaatttagat ttgcttgttc
    11041 aaataataat gtgccttggc tgtcgtagcc gaatgtcaga ttttttattt cgattttaga
    11101 cattttccat cacctcgtaa aaaaagacca gtcctatttt cagaactggc taaagaggat
    11161 gcaagggttg gatacacaca aaaagaccca tacatcgaaa aaaccaagcc aatcccgaaa
    11221 atctgcacac tgcttccttg tctccacaag gtacagtctg aatgcagctt tcatcaatcg
    11281 acttaatttt tcaatgcacg gatccctcac tttgtcctat atttgaaatt acgatagcat
    11341 aaagaaaatg attttgtcaa ctacttcggg aggatggtga aaaatctgct aagtgtctgt
    11401 cctaagattt ttgttttttc taatgtttgc ctgtgttcca ttgcttcttc taaacctatt
    11461 ggacccaaat gaatacttaa gacaattggg agaaaatcag aaagtccttc tagctcttgg
    11521 tctctacttc cgcaaatagc gattattggt tttcgatatt tttttgcaag cactgctaca
    11581 ccgtatggaa cttttccgtg gatcgtttgc tgatcgatcc gcccttctcc tgtaatgatg
    11641 acatctgctt gttcgatctt tttttccaat ccagtgattt ggctgactaa atcgaaacca
    11701 gaaaccatct tcgctcccaa caaaaaaagg gctccaccaa taccgcctgc tgctccactt
    11761 cctggaatat catctaaatc cacctcccag aaatctttta tttgctgagc aatctttcct
    11821 gcttgtttat ctaagaaagc tagcgtcgta tctattcctc ctttttgtct tccaaattgc
    11881 caagcagctc cttgttgacc tgtatatgga ttggtaacat ctgcagcgat aatcaatttt
    11941 actttagaaa caagaacgtt tcttcgatca aaatgaagtt ttttagtaga taataaagga
    12001 tttccttctg tgtacccttc taaagaagca cccaaggatt ggagtaatcc tagaccacca
    12061 tcgctacacc cgcttcctcc taaagtgaca ataatttgtt ctacttcttg aagcagtgca
    12121 tctttaataa gttctcctaa ggcataactg gaagcaagtc ggatagtttg atccgttggt
    12181 ttatcaagta gatctaaccc caatgcttgt gcagattcga tgactgcggt gttttttcct
    12241 tgccaagttg tcaataaata gctgattttt cgctgacgga ataagagatc catcccatca
    12301 atggtacgcc atgttcccct gagcgcgtaa tagattgctt ctgcagtatt ttctccgcca
    12361 tctgcaatcg gcacattgat ttttcttcct ttacgatctt cccagccatt tagaactgcc
    12421 tgatttagtt caaatgaaga agcacttcct ttaaatgaat caattgccgc caaaatatcc
    12481 atctgtatcc ctcactttct tcttaagtaa gacacttttt ttcatttttt tcaaacaaaa
    12541 caatgctatt ttcttccatt tttctatata ctaaaaggga actcattgaa taaaggagag
    12601 aaaaaacatg aaaatcgcaa tagctggggc cggagcaatg ggcagccgaa tcggattgat
    12661 gctacatcaa agcggaaatg aggtcctctt gatcgatcgt tggcctgctc acattgaagc
    12721 cattcgtaca aatgggttga ttgctgactt taacggtaaa gaagtggtcg caaaactgcc
    12781 aatctattca ccagaagaaa tcatcgaaag caacgaacac gtggacttga tcgtagcatt
    12841 aacaaaagcc aatcaattag atgatatgtt ttgttcgatc caatccatta ttactgacaa
    12901 tacttatgtt ttgtgtttac taaatggatt aggtcatgaa gatgtactgg aaaaatatgt
    12961 gccaaagaaa aatatcttat ttgggatcac gatgtggaca gctggtctag ctggtcccgg
    13021 aaaagtcaca ttgttaggtg atggagaaat cgaactagag aacttggaac cagaaggcga
    13081 agcatttaca aaaaaagttg tagaagtctt tcaagaagca aatttaaatc cgatctatag
    13141 ccataacgtt cgttattcca tttggcgaaa agcttgtgta aatggaacat tgaatggttt
    13201 atgcacgatt ttggattgta atattgctga actaggcgcg caaaaagcgg cagagagcat
    13261 ggttcgaaca atcgtatctg aatttgcttc tatcgcagca aaagaaggaa tcatactaga
    13321 tcaagaagaa gtgtaccaac atattgcttc tacttatgat cctgacaaca tcgggttgca
    13381 ttacccatct atgtaccaag acctgatcaa aaaccatcgt ttgactgaaa tcgactacat
    13441 caatggtgcc atttggcgaa aaggacaaaa atatgatatt gctacaccat attgtgcctt
    13501 tttgacccaa ttagtccatg caaaagaagg aatccttggc gcagaataaa aggctctctg
    13561 atgagaatca gctgaatcag cagctggttc tcttttttta agcccaataa aagatcaaaa
    13621 agaaaacaca actctcatga tgccataaga attgtgcttg tttgtttcag tacataatct
    13681 cttcaaaatg taggtttttt atttgttttc aacagaggag aggtcatatt cgtattgctc
    13741 ataaatagtg gaatcgttag tgataaatcg ttttgcccaa ttttctgcat cataaaattc
    13801 caatagctct gataggattg gcttaaatgg tgtatgcaga aattccggta attcatctaa
    13861 atcacgttct cgaagcaaaa aaatattttc aggacgataa aaatgataat gagcaatcgc
    13921 ttgattatcc gtcactagtt tcttttgaaa atacatggat tcaaatgtcc gcaaagtcac
    13981 tccttgctga ccctcccgca acagttccag aatcccgcgc gattcccctg tttttttcag
    14041 gtactcttca taagtaagat atccaggttg ttcattccct cgatgtggaa gaatgaaata
    14101 gttggtcgta acatctcttt ttataaattc ctgcttatag ctttctgctc gttcttttct
    14161 cccattattc gttgcaccaa aaaatagatc cgtctttggt tcgctagaag aaaaattcat
    14221 atgtttcgaa taaaatgaac tattatgttt cagcccaagt tcttttgctt ccaaaaaatc
    14281 aaaatgataa atctcatcga ttgccggttc atcttgtgcc tgcttcagca tcgcctcgtg
    14341 ttctgctttg aagtgattcc aaaaaaataa cacaattttt gcattggtaa atgggcgcac
    14401 gcgtcgagcc atctccatat caaatccata atctaaaaaa acgatcagct gataatttgc
    14461 caactgttgt ctagctgatt taatgaattc cgactgtagt aaatcttttc cggaccaaac
    14521 atctaaagag cggatggaag gcaaaaaata aagtgattta ttttttgcaa ctagcagtac
    14581 gtcatttttg ttcatctttt ccgcctcact ttctctgtca ctttttccta tgatagcctg
    14641 tttaaatagt aaaaagccag taaaacgttt cctatatttg tatgaaaatt taacatttgt
    14701 atgaaaatat gatgaaataa atcattcttc tattaaaatt cgcctaaaag ttttctgaat
    14761 agttgtaatt gtctgaaaat ttgttatcat tagtcattgt taaatattgc tatttattct
    14821 taatataaat tttgattgtg aatttaaaag aaagaggtca tttatggaag ataaaaaatt
    14881 gaaaaaacaa cttagctcca gacatatcac catgttagct ttaggtggag caatcggtgc
    14941 aggtctattt aaaggaagtg gcgaagcgat tgggatcgcc ggcccttctg tattgattgc
    15001 ttttttgatt ggtgggctga ttttatatat cgtgatgaaa ggtctgggaa aaatcgtttt
    15061 aagcggtggc gacacgcatc acggattatc tggtttgata cgcccttatc taggtgctca
    15121 ttctgctgat tttactgatt gggtctactg gtctatgtgg attatcaata tcatcgctga
    15181 agctgttgca gctgcttcct ttttgcagtt gtggttcccg cacattccag cctgggtatt
    15241 tgtttttatg ttggctgttt taactacgat catcaatctt tattcggtac ggttattcgc
    15301 agaaacagaa tattggctgg cttttgctaa aatcagtgtc attatcttac tgatcatttt
    15361 tgctacttat cttgtcggtc agcaaatgtt gggcacaggc gttttcccta cccttcagca
    15421 attgactgac catggtgggt ttactcctca tggtatgaag ggaatcatca gttctttgct
    15481 tgtagttatc tattcttacg gcggttctga actgattgct atcacggtaa gcgaagcaga
    15541 tgatcctaaa cgtgcgattc ctaaagcaat caaaggtgtc atgggaagaa tcatttcctt
    15601 ttacatcatt cctttgtttt tgcttttgat tctttttcct tggaatactt tagcaggcac
    15661 gaatgtcagt ccttttgtga tggtatttga aaaaatgaat atcccatttg cagcggatat
    15721 cgtcaatttt gtgattgtcc ttgctttgtt ctcatctatc aattcgggtg tgtatgcatc
    15781 ttcaagaatt ttgttcttcc gtttgaagga tcgaaaaggt tcctctagaa aactagctgt
    15841 tttaaacaag catcaagtac cgcaacgtgc tgttttattt tgtaccagtg ttctttatct
    15901 tggtgtagct ctttcttatt ttgtcggtga caaattattt ggctatctgg caggttccct
    15961 ttcgtataca gtattattga tctggatcat tatcagtgcg gcatcctttg tactggcact
    16021 aagaaaagga acattatggg ataaaggaat cagctttttt gcattagctg tcttaggatt
    16081 gattttcctt ggtatcctgt tcacgaactc cattggggta actgtattga ctggcctgct
    16141 ttacctgttc atttatttca gttatcaaaa aaagaatgat gcgttcgtat tgacgaatga
    16201 atgaaatcga tagaaaattt tattttattt atgtggaata gatggagcta ttgaagaaag
    16261 gagttgtgac aaaagtcttg ttgcaactcc tttttccgaa taaacagtct catgacctct
    16321 tggtaaacgg tgttcaaaaa ccctctgtgc aaaataattg attgttctcc atgctcatga
    16381 catgatagaa gaaaggaatg aaaaaaagga gtttgtttta aatgaaaaag tattggaagt
    16441 ttttgttgat gatcggtgtt tcaacggtag ttatgtttgg tatgatgtac ttgaatgtct
    16501 atgcgctcga tcatatcttc ttcagtcgta cacgagtatt catggcgttg atgatgggtg
    16561 cagtcatggc agtcatcatg ctgttgttca tgtggaaaat gtatgaaaac aaaaagataa
    16621 atgttatgat cttagccgct agtcttcttg tttttgccgg ttccttgttt atggtacgaa
    16681 gccaaactac tgtcaacgac acagcttgga tgaaggccat gattcctcat cattctatcg
    16741 ctatcctggc aagtaaacga gctgatttaa aagatcctga agtaaaaaaa ttagcggaag
    16801 aaatcattca ggcacaagaa gaagagatcg acaaaatgaa aaaaatgatc aaagaaatgg
    16861 aatgaccatt atccgtccaa ataaaaaaag aggatgttcc agaagttatc agcttcaaga
    16921 aataagaaga agctacttct ggaacgccgt gaataagggg ttgtgaaaaa gctgccctgc
    16981 atcaagtaat aagaacagcc aaacaaaaat agcttctcct atttttcgtt tggttaggct
    17041 tattaccgca gatgcaagct tttgaacacc gtttattaag aggttgtaaa atcagcgttc
    17101 tgacctgagt attagagaga caaatggaaa aatagttcct catattttgc cattttttga
    17161 gctaataccg agggtcagct gattgaacac cgtttatcga gaggttgtga aaaagtcgct
    17221 tagtttcgcg tattaagaaa aattttgtga aatggctttc cacatttttg tataaatttg
    17281 gcttaatacc gagaaactgg cttttgaata ccgtttattc gtaaaaggga ttgtgacaaa
    17341 agtcttgtca caatcccttt ttatgttttt attgttctaa ttgcgctgtc ttgcttactg
    17401 cttcttgcgg tttcacaaat ttttttgaga ttccccaacc tgtgaaggca ctgaccatcg
    17461 aaaacacagg agaaagcaaa ctgaaaaata cgaatggcaa gtaagtgagt gtaggaatac
    17521 caaatgtact tgctacgaaa cttccggcaa ttccccaagg cactaagtag ttgattactg
    17581 ttccaccatc ttctagcgtt ctacctaata cagttggatc aaatcctgct ttttcataag
    17641 tttctttaaa tgcattacca ggcagaataa cagataggaa ttgttcacca ataaaaatat
    17701 ttactccgat acttgtcatc aatgttgtaa aaatcaaatt tggtgtgttc gtcatctttc
    17761 ttgatactcg ttccatcacg gttgagatca agccaaattc gatcaacaat ccacctaatg
    17821 acaaagttag aataatcaat gacacagtag gcatcatact ttcgattcct ccgcggctaa
    17881 gcagtgaatc gatttgttgg tttccagtat ttgaaacaaa ccctgattcg atgaccccag
    17941 ccaacttcgt taaggaagtt tgtgggtttt gaataaaaat cattcctact gctacagcga
    18001 tattcaacaa aatcgttaaa attgccggca cctttttcca tgcacacagt aacattaaaa
    18061 ataaaggaat cagtgaccag attgaaatag taaagtttgc ttctagaaca tcagtcactt
    18121 cacgaataga tgaaagactt gcggctttac ttgtgtgtcc taaaatcatg aataaaaaga
    18181 aagaaacaac aaatgccggg acagttgacc acatcatatg cttgatgtgt ttgaacaaat
    18241 cggcatcaac aatagctgct gctagatttg ttgattcgga taatggagac atcttatctc
    18301 caaaaacggc acctgaaaca atagctccaa caaccagcgc tggatttaag cctagtgttg
    18361 tcccaatacc gaaaaatgca atcccaatcg ttgacataac agtaaaggca ctccctacag
    18421 cgctacctac gattgcacac acaacaaata cagaagggac aaaccactgg acactgatca
    18481 atttgaaccc aatgaccatt agagttggaa tgatccctgc ttgtatccat acagcaatca
    18541 atgaaccgac taaaataaaa ataaagattg ggatgattcc tggtttgatg ccattgatga
    18601 ttccttcgtg cagccaatct gtcgggtatc tttttatcac tgcatacaac atgaccattc
    18661 cgatcgctgc taagatcgtg atattaggtg agacctttaa tccgacaacg ccaatcgcaa
    18721 tgcctaaaac aataaccatt aatacaagtg ttgcttctaa aaaacttggt gttccttttt
    18781 ttcccatgat aatctctcct tttttagttg ttcttatgtt ctaaaaaagt taagatatcg
    18841 gattactccg ccgcaattca tccgcgattc ctcctttata aaaataaaaa gacctgtttt
    18901 aaactaagga cgaatgactc cgcggtacca ccttaattaa aaacagatct gtttttcact
    18961 ttcaaacttt tattcaaatg tatggacttt ccatgtaatt cgtcaattag gcttgatcgg
    19021 ttcacagcga ccaccgactt tctgaacaaa acacctaacc gctactgcgt gaaaagttga
    19081 cttgtacgaa gtttaccttc cataagatca tttgtcaatg aaaaagaaaa tattttttca
    19141 tttttctgaa aattattttt ataactttca cacacaagtt tattttttac tagaaagtag
    19201 cgccctcttg tttttttctt gctactattt cttgatgttc ttgcttgatt ctttctaata
    19261 gctttggctc tttcaacaga tcaagagctg tattggcgag tagttctgct gcaatcgcaa
    19321 tagaagcaag gcctttgtca cttttagcag cagctttgaa ttcttctgtg tgtccggcaa
    19381 tatatgtctc agagattgct accgtaggct ggattgttgg tatgacttgg ctgacatttc
    19441 ctacatcaga agaaccgaga cttgttcttt gttccgtttc tatttcttca tctggaacac
    19501 ctgcttcttt tgcatgctgg aagaataagt catcaaaaga aggagtaacg atgacatcat
    19561 caactgcatt ttggaacaat ccaaactcaa aagtcgtgcc cgtacttatc gcagcacctc
    19621 gtacgatatt ttccactttt tcatatactt tatctaatgt ttgccgattt cctgcacgta
    19681 aatagaaacg tccagcagcg taatctggaa tgacgttggc agctactcct ccgtctgtaa
    19741 tgatcccatg gatattgaca tcttttggca attgcaagcg tagagcgttg attccattaa
    19801 acacttggat caatgcttcc aaagcattta ctcctttttc aggtgctgct gctgcatggg
    19861 aagcgacacc gtaaaatttg atgtcgactg gatcattcgc taaagattct gtcgttttcc
    19921 cataacgaaa agctggatgg acgcataacg ctacatcgac atcctcaaaa aaaccttctc
    19981 gaacaaagct gcctttagct gatccgttct cgcccccttc ttcccctggg gtgccatata
    20041 cacggatttc tccaccagtt tcatcaatga attgcttcac tatgctggcg gctaatacgg
    20101 agtaagtacc aaacaaatta tgcccgcatg catgaccaat acctggtaaa gcatcgaatt
    20161 ctgccaaaaa ggcaattgtg ggaccgggtt tattggaaat ataacgtgca tcaaaggctg
    20221 ttcggtgtcc agctacttct ttttctaccc aaaacctttc tttttctaat tgtttaatca
    20281 acgctgctga ggaataaaac tcatagttac ttacttcagg atgttcgtgg atatctagag
    20341 caagtgcttg atattctggt aaacgatatt ggattagatc cttcaattgg tttgttgaga
    20401 ttgttgttgt cataaaaaat tcctcctatg ctagtcattt ttcttatttt ctcccgaatg
    20461 tttcccatgc aggcacgctt gatccttttg atgttttctc gattactttg actgtgtctt
    20521 ctgtttgata agcgtctact attttttgat acgttttatt gttttcatct tcttttcttg
    20581 caacgatgat attcacataa ggacgtgcat ggtcatccac tggttctaag aagatggcat
    20641 cagaagcagg attaaatcca gcatctacag ctacaccgct attgatcact gaaatgtcta
    20701 catctgacaa agcacgtgct gtttgggaag catctaattc agaaatgtct agattttttc
    20761 tattctcggt aatatcagaa acagtgggcg cttgtccttt tgccttatcc actttgatca
    20821 atccagcagt ttgcaataac agaagagctc tgccgccatt tgtaacatca ttagggattg
    20881 ctacttttgc tccgtctttg atatcagcta catccttcaa agtgttagaa taaattccca
    20941 gcggtgcatt gacagtattt ccgatcgata ctaaatcagt tccgtgttct ttattgtaat
    21001 tgtctaaaaa gaattgatgt tggaaagaat tcaaatcaat cgatccatct gctaaagcca
    21061 catttggttg attgtaatct gtaaatttca cgtattccaa attaatgttc tcctttttca
    21121 aacggtcttt cacgttgtcc catacatctg tatcttctcc aataatccct agttttacga
    21181 tagtttcttt tttgtcagtt gtatctgctt ttccttggct acaccctgcc aaccaaataa
    21241 ttgctacaaa tgtaatgact acaaaacgaa taattttttt cattttttct cctccacttt
    21301 caatgtgtaa tttttttaat cagttgatta ctgataaatt gacttaaaaa aactaagatt
    21361 agaatcaata atgtagccac aatcgttaca tctgtttgga atcgattata ccctctcgat
    21421 atagcaagat tccctaatcc gcctgcacct actgctccag ccatggtagt cagtccgatc
    21481 acgttgatga tagtcaacgc cgagacccga atgataccag gcaaaccttc taacaaatac
    21541 acacgtaaaa tgataccgat tggactggtt cccatcgctt ctgccgcttc gatcacccca
    21601 ggatcaactt ctagcagtgc gttctcgatt tgacgagcaa aaaacggaac aactccaaaa
    21661 atcaatggca ctaaagctgc tttcgcacca atcgtcgttc caactaagaa acgagtagtc
    21721 aatgctaaaa gagaaagcaa gataatgaaa gggatggaac gaatgatatt gatcagctta
    21781 tcaagtattt caaatagcag acggttagct agtaatccat tagggcgtgt cactactaac
    21841 gtcacaccta agatgattcc aatcatcccg ccaatgaatg ctgtccaaaa agacatatat
    21901 agtgtttgct tcgtcgcttc gacaaattca tccggaatca aataaacatt gggcaaatat
    21961 gttttaaaga aatcagtcat tttatcttcc tccttcgatc actttgatac gactatctaa
    22021 atcgtttttt tgtaaaatat ttatttttac accagatttg atcaaataat ccaatgcttt
    22081 tttccgctgt ttggtttctc cagctaaagt aacgatcaaa ctccctaacg gcgtttcttg
    22141 taataactct acattgccat ataaaatatt cgctgttact tgatatttgc tgtacagatg
    22201 agcgattaga ggttcgttcg tctgatttcc aatataactt aattccacca gccatttatt
    22261 ggcgatctga tcggcaaaag cagaatgggc aatgatcgtt tctaatgctt ggtcaagatg
    22321 agtagctgtt cgaataaaat ctttggtcaa ttcttcttca ggattgctga agatctggat
    22381 gctgctacct ttttcaacga ttcttccatc ttccataacc gctaccttgt tgcagatttc
    22441 tttgacaact tgcatctcat gagtgatcag gacgattgtt aaacctaact ggcgattcaa
    22501 tttttttaac aatgcaagga tctgaagggt cgttttcgga tcaagtgcac tggttgcttc
    22561 atcacataat aataccttag gttcattcgc caaagctcgt gcgattgcta ctcgttgttt
    22621 ttgtcccccc gacagttgtt taggataagc agatgctttt tcttccaaac cgacaagttc
    22681 cagtagttca ttcacttttt gacgacgttc ctgtttcgat tttccagaat actttaaaga
    22741 aaaatcaacg ttgtcaaaaa tagttcggct ttccattaga ttgaaatgct gaaagatcat
    22801 accgatggcc tttctttctt ttcgcaattc tttgggagag agctgactca gattcgtctg
    22861 attgacaatg acttctcctg ctgttggttt ctgcagcaaa ttcatcacac gaactaacgt
    22921 acttttccct gcacctgagt aaccgacgat tccataaaca tcgccttttt caatcgttaa
    22981 atctacagaa tctactgcct gtatctcttt ttctttttgt ttgaaacata cagaaacatc
    23041 tcgcaattca atcattaaaa ttcctcctta tctaaaaaaa gcgtcctcaa gaaaatgaaa
    23101 atgtcatttt cttgaggacg cttttttgcg tgttaccacc tcatgttcaa gctgtgttca
    23161 cacacaactc ctcttcaagt acgatcatac tctagcaaga tatcggtcgc agccgtcatc
    23221 gccttacatc tatgctcggg atgaattgct cgatggccat tttccaatag tcgttccttg
    23281 cttcttctca gctaccgaag ctctctgtca aaggttcttc tatcgtactt accatttcaa
    23341 tgcaaataat attcaaaaaa aaagtccttt tactaacata aactatgtca gtaaaaggac
    23401 gacgtatcgc ggtaccacct tttttcggaa gtttccttcc ctcaagccca acatctcaaa
    23461 aagagagatt ggcgttcgtt ttaacggtcg aacagttccg aatttgccta cttatcgaca
    23521 aattattctc caaggccatt ttcagctttt cttacttgac tcttctcacc agccagagcc
    23581 tctctgcaaa gtttccaaac ttactttcct tttcaacgaa atcgatattt tgttgttggg
    23641 attaatctac atgaggaaaa ctgaaaagtc aagtacgaaa ttcaaattat tttttctata
    23701 tttatttttc tgttttttta tttaacattt caataacagt tcgaagatct tttccttccg
    23761 caagaagttt caatttttcc ttttcttcga cggtataatt tcggacaaaa ctggaatcag
    23821 gtatcaaaac aacgcctaat cctgctcgtg aagcagctgt tgctcctact aaagaatctt
    23881 ccactgcaaa ggctgaacta gcttctaatc ctgttcgttc caaagctgtc agataaggaa
    23941 tcggtgaagg cttgttctcc gacacttcgt ctccgaatgt aaacgtgtcc aagtaatcag
    24001 ctaatttaaa gtgatccaag atatctgttg ctcttttcgt aacagtggtc gtagcaatgc
    24061 ctagtttcat atgacgttct tttaagtctg ccaatatttc ttttgcatat ggttttaagt
    24121 ggatggctcc gcttgtcagc tgttgataaa aatattcttc acgcttcgct cggacttcct
    24181 gtactttttc agggctacct gctgctttca ctaaaatatc aaaactttgt ttccagtttt
    24241 ttccgcccca agcgtcaacg atttcttttg ggatatggat atcaaattgc tgaaatcccc
    24301 aaagccagcc atcacgatac gttttttctg tgtcaactaa caaaccatct aaatcaaata
    24361 ttgcaccttt catctataca ttaatccttt ccaaaacaat acacatagtt tagcacgact
    24421 ggtccaaaaa gaacagaagc aaagaaccag ccttctcgtt tataagagtt cttggaatcg
    24481 acggatatag attttcttca cagctgtcac aagcgccaga taagcgatga ctgtagcaaa
    24541 taaccataac cagtaattgc caggaagtgg catcaagcct aattcagcac caaaacttgt
    24601 aaaaggaagg acagaaccga caataattcc taatgtagtg ataacaaaca tggcaaatgt
    24661 tgcgttgctt tggataaatg gtactttcgg tgtacgcagt gcatggagca ctaaggtttg
    24721 tgtccatagt gattcgacaa accatcctgc atggaataat gcgatgaaaa tcactcgctg
    24781 tgaactatcc aatgtatgga aacttccgcc cactacagca ggacaaataa caaaatacat
    24841 caacaagtaa gtagtaatat caaatatcga acttgttgga ccaaagtaaa ccatgaattc
    24901 cccaatacta gatgcattcc atttttttgg ctcgtccaaa tattctttat ccatccgatc
    24961 ccatggcaag gaaatgcagg aaacatcata gatcagattc aaaaacaaaa gttgtaaagg
    25021 cagcattggt aaaaatggca ggaacgtact tgcaatcagc acggaaaaca tattgccaaa
    25081 attagaactt gctgtagcct tgatatattt catgatattc ccaaaagttt ctcgtccaga
    25141 aagaaggcct ctttccaaaa tcgtcaaatc tttttctaaa aggatcacgt ctgcagattc
    25201 tttcgcaata tccacagctg tatctacaga aataccgata tcagccactt tcattgcagg
    25261 agcgtcattg ataccatctc ctaaaaatcc gacagtatga ccatttttac gtaaagctgt
    25321 cgtcaaacgt gctttttgct gaggattcaa ttttacgaat acttcatggt cttcagctac
    25381 ttgtgctaat tcatgatcac tcatttccga gattttctca ccggtaacca attcattgat
    25441 ctctagacct acttgacggc acactgaacg tgtaactaat tcgttgtccc cagtcagaac
    25501 ttttacagct acaccatgtt ctttcagagc tttcaacgct tgtttcgttg tttcttttgg
    25561 tggatcaagg aaagcaagat aaccaatcaa aaccatgtct gactcatctt tgactgaaaa
    25621 ttctccaacg acgcttggat tggtcttttg tgcgacacca atcactcgta agccatcttc
    25681 attaagtgac tgtacttttg caagtacggc ttcttttcgt tcttttgtta atggtgtaac
    25741 agtaccgcca agatcaataa atttagaaat gttcagcatt tcttcaatcg cgccttttgt
    25801 gatcatttgt gttttaccag ctggatcagc aaccacaaca ctcatacgac gacgttcaaa
    25861 atcaaaagga atttcatcca ctttttgata attgatctta tctgtatcta aagtttctgt
    25921 tgcttcatca atgatagcca catctaacaa atttttcagc cctgtttgat agtagctatt
    25981 tagatacgca tggcgcaaaa cacgatcatc ttcatttcct tcacaatcca tatgatattc
    26041 aagaatgatt ttatcttgtg tcaatgtccc cgttttatcc gtacataaca catcgattgc
    26101 accaaagttc tggatggcat tcaaattttt gatcactgtt ccttttttgg ccatcacact
    26161 tgctcctttg accaaattcg tcgtaacgat cattggaagc atttcaggtg ttagaccaac
    26221 tgctacagat agtccaaaaa gaaaagcttc tagccaatcc ccttttgtaa gcccattgat
    26281 gacgataact gctggagcca tcaatgacat aaatttgatc agtagcatgg atgttttatg
    26341 gatgcctaat tcaaagcttg attgaattgg tttttcagat agcgtttctg ctacatgacc
    26401 aaatagtgtt tcatttccaa cagaaacaat gattccttcc gcacttccac tgatgacatt
    26461 acttcccata aagacaagat tttcgtaact tgtttcgctt tgctgatcgt cttcacatac
    26521 tttcgcatgc ttttctactg gatagctttc ccctgtcaat gctgcttggg aaatgaataa
    26581 atcctttgcg gacaataaac gcatatccgc tggtatcata tcccctgctg aaagccgaac
    26641 aagatctcca cagacgattt cttccatagg aatctctgtg tactttccat tacgttttac
    26701 agctgccgtt actttcacaa gtgatttcag tttttcagcc gcttgattgg aacgtacgga
    26761 ctgaatcaac gtcattgtcc cgctgacgat aaccatagtg aagataatgg ctacaccgaa
    26821 aagatcttta tctccaggag ctgctaatac atattccgtg atgaatgaaa taattcctaa
    26881 tgcgatcaac actaatgtaa atggcgtgat gtatgctttc aatatttcta caatgaatgg
    26941 tgtttttttg ccatatgaaa tcgcattttc accgtaattt tctcttgaac gttcgatttg
    27001 ttcttctgtc aatccatttg ctgatgcatg gaatagttca aataattctt gtttcgtttt
    27061 tccagcaaaa gctgcataga ttttttgtgt atctttcttt ttttccatct caatctctcc
    27121 tttgtgtcca aaagacagct gttctcgctg cttttggtct ttagctattc atcggatcga
    27181 tagagaaaaa actgaaaggg gctgagaaca gatagataat agccctggcc tttcctctag
    27241 atccttgttt ttcgaatgac tgtcatccat ttgttctcat ctcctttact aagtaatttt
    27301 aattcatgac ttccaatcat ttttcgaata gttatttttc caattagacc acctcctttt
    27361 tatttttcac cgatggggat ttgcggcaac aaaaaaacct ctcgccaaat actcagcgaa
    27421 aggtttgaaa aagcatatta aaaaaagctt ctcagatctc atcgttgagt tttgacactg
    27481 tacaacgtaa aaagcagata cctgctttta gctaccttat gaaaagcctt atctcgacaa
    27541 ttcctgttct acccattggc gtctctcgac gtttttgggc agtagcctat gtttgtatag
    27601 gagcctcacc taacaaatct tattcggttt tccttcgtta atataacaac taaaaaagag
    27661 gatgtcaaat caattttcca tgtttttcat acttttttta aaatacacac gttatattcc
    27721 tgtctcacgc ggttttattt gtctcatttt ccacctcccg ctataataga aatatagtag
    27781 gaaacgaggt gctgttatgg aaagaacact tgttattatc aagccagacg gcgtgagacg
    27841 ccatttagtc ggaagcatca tccaacgttt tgaagcaaag ggactggcca ttgctgaaat
    27901 gaagtttgaa actatgactc ctgaattagc aaaagaacat tatcagcact tgactgagcg
    27961 cagttttttt gatgaactga tcgattacat gacttccggt cctgtcgttt atcttgtgct
    28021 ggtcggcgag gaagtgatcg atatcgtccg taagatggtt ggagcaacaa aagctgccga
    28081 tgctgttcca ggtacgatcc gaggagacta cgcgctgccg gggactgaaa acatcattca
    28141 cgcttctgat tcccgtgatg ctgcggtaaa agagatcgcc cgctttttcc cgccattcga
    28201 tataaacaaa ccgtctgaaa aagcggcgaa gtgatacaaa ttctaaactg ctggtctagt
    28261 tgctgggttc agcaatggcc agcagttttt tctctaagga cctccgttga ttctttccta
    28321 acatatattc gagcactgtg aagaattctt ggtagtcttt cgtcttttct tcccctaaag
    28381 cagcagaaat caatctttga taataatctg ccatcaatgt ttcatagatc actgtacttc
    28441 tttctttatg tgataagctc cgtttcatat cttcattcac actacgtgcc tttttcaacc
    28501 gaccattttc tatataaaac gaagtcaggt tcattaaaaa agtaaagaga tactgctcat
    28561 gattgttcaa ctgtgctaat cgtcgcattc tttttttgat tttcaaataa ttgttctcaa
    28621 tgaaccgatc actgaatatc caaggaaaat cagctagaat agatagttca aattgaccat
    28681 agtctggtat ctgcatcaag tattcttcaa tgattcggca ttcataacgt aaaaattcaa
    28741 attctgtctc agatacttct gttttttcga ccatgtgaag attcaaaacc aaataataca
    28801 gatcttctgt tttcttaaaa tgcctacggt tattgctgat ctctttataa ggatcaaagc
    28861 tgtcttcttg tacccgatct agcattcgtc tttttttctt taactttatt ggttcatcca
    28921 gctggtttcg catccattca tattctgcaa gtgtcatgtt cattcgctct aaaaatgatc
    28981 tcaatgttac aaatgacatt tttttcactg aatttgtctc aatcccgact agagaagtct
    29041 taaaacagat tccttccgct aattgggact gtgtcaactt cttgttgact cgaagtttct
    29101 tgatcaattc accatcatac ataatagttc tcctttttaa tttaaatttt tccacattca
    29161 ataaatagat acgttaaaaa ggaaaaatac acgaaaaaaa taaaaaaatg tttttttcat
    29221 aaaaaatacc aaccttcaag cattagaatg ttgtctaact actgaaggtt ggtttgattg
    29281 tttattgatt atttttttgc tgttcaacgt ctgttcttgt tactggatat aagttggttg
    29341 ttgttttatt accatttttt gaaaagacac ttgtcgaatg ttcgcctttt tgcttttcga
    29401 ttgcttcatt acgttccgct tcatttttat agtcatattt tttcggatca atcgtctcaa
    29461 atccgtttgg cacataaaac cgcaagagat tttcctgatt cagcttatct gaaagactta
    29521 acgcagtctt gactttttcc tgatctttgg agatttcctc atcgattcct gctgctttcg
    29581 tatcgatgat ttctcctgtc tgattattgt aagcttttcc tcctaggacg gtgtatttgg
    29641 gtgtcacaaa gttcccattt cgaaaagcaa ctacttgatc atgctgagaa gataataagt
    29701 ctgtaccaaa atgaagataa tctttatcat cgattcccaa tagatgtagt aatgtcggca
    29761 aaacatcgat ttctccaccg tattcatgat tgactgtccc tttagtataa ccaggcatat
    29821 ggatcatcaa tggcactcgt tgcatctgtg cgttgtcaaa ttcatcccat gtatctggat
    29881 ctttaccaag agcgcttgct aaatctttat tatctgtatt cgagatccca aaatgatccc
    29941 cgtaaatcac aaagattgaa ttttggtaaa taccagattt tttcaaatac gtaaaaaatt
    30001 gttccaatga ttgatccaga taatgtgccg ttcgaacata attatctact gtgctattgc
    30061 cagtattcaa agatggaaag tcgaaattct tgtcatccgt ataataaggc gtgtggttgg
    30121 ttacggaaag aaatttcgtg taaaacggct gttgtagatg ctcaagatat tgggcagatt
    30181 ctctgaataa atctttatct aatatcccat aacctaacgt ttcgtcggat tcatcaaaat
    30241 aagatcgatc aaagaaattg tcataaccta agtttttata tacatgatct ctattccaaa
    30301 aactagctac attcccatgg aaaacagcgc ttgtatagcc ttgcttttgt ccaaggatcg
    30361 ctggtgcggc ttgaaagaca ttgtctgacc caagttctgt gaataatgag ccttgaggta
    30421 aaccaaatgt gccagtttcc aacatatttt cagcatcact tgtctttccc tgtcctactt
    30481 catgaaagaa attgtcaaag ctgatcgttg cttgattctg gaaaatacta tttaaaaacg
    30541 gtgtgacttc ttgtccgtct accttcatat taatcaaaaa ctgctggaaa ctttctaaat
    30601 ggagaacgat cacatttttc cctttagcga tcccaaatgt ttcgggattt ggctctgcat
    30661 aatgtttctt tgtataatct aaaacttcat caatcccatt actgcttgca tgcgcgcgaa
    30721 cactgctagt cattcctgtt ttgattccgt cataaatagt atacgcatcg attcctagat
    30781 atttgacaat atatgaacgg tcaaatgttc gctgcagcaa ttgtggacgg ttggcttcgc
    30841 tcagcgctag atttcctgaa aaaataagcc ctgaaagaca ggtaacagcg atagccatcg
    30901 gtttgccgac agggttgctt ttgataggta ttttcttgac cttcaaccaa accagtagcc
    30961 caatgaacac agcgatatcc agccagtaga tgacatcatg gggcttcatc aaagaaaagg
    31021 agcttcctga caatccttgc gacactttcg aaaagcctaa tacagatttg actgtaatga
    31081 aatctgtgaa ttcccgataa aaaataatat tcaagtacaa caaaagcgta tttaaaatat
    31141 caatgatcaa aagaatagct aacgctggct ttggcttttt aatatacaaa gaaaggccaa
    31201 aaaacaataa ggtagtcgca attgggttga tccacaagat aaagtactgg atcgtacctt
    31261 ccacacctaa tgaaaaatct gcatagtagg caatgatcgt cttcagccag aaaaagaaaa
    31321 cagctgtcaa aacgattgct aaacgatttt ggcacaattt tttaagttgt gtcacgtata
    31381 tcacttctct ctattcacat tttttcttat tttgctcctg aaaaatgaaa atttcctaaa
    31441 aaagttgtta tcttaagatt tttttattct ttctaaagat tattccgtcc acttttcaca
    31501 gcataaaacc gctgcgatgt aagcgattaa actaatgaag agataaaagt cttgtggtga
    31561 ccgcttcact ccacggtatt caaaagccag tttctcggta ttcgtacaaa aaaagaggct
    31621 gtgacaaaat tcttgtcgca gctccttatt tcttgatgca ggacagcttt ttcacaactt
    31681 cttccttaaa cggtgttctc ctgccaactc ctcggccaca agtcacaata tttataaaac
    31741 atgagaagct gttttttgaa attgttcctt gtggctcaga gttaaacggc aggctcaaga
    31801 cctcttgata cacggtgttc aatcagctga ccctcggtat tagattatgt caggacgcta
    31861 attttacaac ctcttggtaa acggtgttca aaagcttgca tctgcggtaa taagcccaac
    31921 caaacgaaaa atataaggag ctattttttg aaattgctcc ttgtggctca gagttaaacg
    31981 gcaggctcaa gacctcttga tacacggtgt tcaatcagct gaccttcggt attagctcaa
    32041 aaaacggcaa aatatgagga actattttgc cgtttgtttc tctaatactc aggtcaaaac
    32101 gctgatttca caacctctgt ttttcattgt ccataggatt gatattgtcc ttgtgatgac
    32161 tcattcgtaa taattgaggc ttgattttct tcacttcccg ttatcgtttg tccactgcca
    32221 gaatctgaag gacttgttcc tgtcgactcg tttttttgag aagagacagt tgttttcttg
    32281 acttgttcat ttgtcttttt ccattccgct aaacgatcgg cgaccacttt tttgtctact
    32341 ttttcagaat aagcggtgat cacttttcca tttttcaaac gggctacttt gtcgccatca
    32401 tgagtcaaaa gcaaaacggt caaatgcttg tctttaaatt gatattgtct gagagaaatc
    32461 gcactaagta cgtcatcgat attaataaat tgattttctt cttttccttt tggcaaataa
    32521 atgtccaatt cgcctttttc gtaattggca gttattttat actccgccca ccaataagtt
    32581 gagaattctt ttttgaaatt atctactgat tctttgcttg ctacgatttt ttctgtttct
    32641 ttctgagcaa gatctgctgt catttttcct gaaaatgctg cggataaaat aagcagtaag
    32701 aaaaaaccga ataaccaaaa gagaagaaac ggtctttttt tcctcatgct ttcctccact
    32761 cctatttaat tttgactatt ctattatata caaaaaatga aatagaaaga caaaaaagtt
    32821 gaaaaagatc gtaaataatt gaacttcttt ttcacaaaat ggtaagaatg gagaatttca
    32881 cgcatttgct ctcaactatt ctttcttaag cctcaaatcc gtttttatct gatacgtctt
    32941 tgaaccaatg acccgatttt ttgattgttc tttttccatc ttgtgctaag tctactgaaa
    33001 taaagccata tcgattctta tatgcattgg tccacgacca gttatccata catgtccaca
    33061 tatgatagcc taaacaattg gcaccttctt gaatggcttg atggacatat ttcagatgag
    33121 attggacaaa ttcgatccga taatcatcgt ggatcatgcc atcttctttg ataaatcgtg
    33181 cttcgttttc tacacccata ccgttttcag aaataaagca gtcgatattt ccataatgat
    33241 ctcgtacatt gatcaaaata tcatagattc cttgttcata gatctcccat ccgcgataag
    33301 gattcatttt acgaccaggc atttcataat tgtcgaaata atcctcaggc attggaccgt
    33361 ttttagtatc gattggtgtt tcttttgctt ttacccggcg tggctggtaa taattgatac
    33421 ctaaaagatc tactgtattt tctttgataa ccgtcaaatc ctctgcatgg atcacaggca
    33481 tgagatcaag ttcttttact atctcaatca attcacttgg aaactcgcct tttacagctg
    33541 gatcaaggaa tgaacgattg aagaacgcat ctgctatttg cgctgcttta acatcttcag
    33601 ggtttgattc gtctcttgga tagcttggtg tcagattcaa gatgatacca ataacaccac
    33661 cttgctccat ttcatggtaa gatttgatgg ctaacgctga agccaacgct tcatgatagc
    33721 caacttggat cgcttttttc atatctgact cttctggata atgccatcga tataaataac
    33781 ctgcttcgac tggaacgatt ggttcattat gagtaaacca tttttttact ttcgaaccaa
    33841 acaattcaaa acaacttttg gcatattttt cataggcttc aaccgtttct cggttcaacc
    33901 atccgccttt ttcttgcaga tacatcggca tatcgaaatg atacagattc acaaagggtt
    33961 cgataccgtt ttcaatcaac tcatcaaaat aacgatgata gaaacgaacg gcttcttcgt
    34021 tgattgttcc agattcatca ggtatcaaac ggctccattg gatagatgtt cgaaatgaat
    34081 tatgcccagt ctgtttcatc aactgtacat cctcttgata cttcgtataa acttgcgagg
    34141 ttttttcagg tcctacttga tcaaagaact tttgcggttc ttttttgtac caataatcaa
    34201 aaatgttctc tccttttcca tcgcctgaaa tccttccttc tgtttgtggg ccacttgctg
    34261 cagaacccca ccaaaaattt gctggaaatt gatatttttt catcaaagca cctctttttc
    34321 ttttttagtt cgttttagtt gattccatgt atgatatttt ccatcacaat cactttttca
    34381 ttttcttcct cttctttttt gattcgtttt aacagctgtt ctgctgctcg ttccccgatt
    34441 ttatctgttg gtggcgtgat cgtgattttc ggaaggatac tcagatcgtt tttatctaaa
    34501 taatcatagt gactgaacgc aatatccttc ccgattctga caccttcttg attgaaacat
    34561 tcgatggcac caatcgacat attgtaattg ctgacaaaaa tagcagttgc ccctttttct
    34621 aataatgctt ttgccccgta atagccgctt tttctagaat agtctcctgt aaagacctct
    34681 aattggatcg atggatcatt ttggaccgct tctttggctc ctgctaaacg ttctcttgct
    34741 acgtagtctg tttgagtggc agcaataaat ccgatttttt tatgtccttg ttcaccatga
    34801 tgagcgatca cttttgctac actttctcga tcattcacta atattgtatc aatacctgct
    34861 ggtccttctg gacaattcaa tgcgataact ggaatactca tttttgtgag catttcaaat
    34921 ccagaccact cttcttcgga taagaagaca atcagcccat cgatcacatg cttcatcagg
    34981 tattcaattt tttgttcaat tttttctggc tgatcggcaa acccgcttaa taataagcta
    35041 tacccatttt cttcagctac tctttcgatc cctgagacaa cttccgaccc aaaacggctg
    35101 gaaatcccgt ttatcaaaag tccaatagag aagcttcgat tattcttcaa ccctttagca
    35161 atgatgtttt ctttatagtc caacgctgaa atcgcttctg ctattttttt catgttcttt
    35221 tccttcagtt gctgaccatt caagtaacgg gaaactgttc ccactgaaac accagccatc
    35281 ttagccacat cacggatcga tgccatacat tctcactcct gccagttaca tttgatttct
    35341 ctttcttgtt gttcgattat gatgaccgca ttctttgcat agtgttgctt gtcatcaata
    35401 tccatataac taaagtcttc agtagagcaa cttcctctca ctattaatta tacttaaaca
    35461 agtatttgaa ccggttcatt tttaatatag cattttttta aaagattgca acactttttt
    35521 aaaacgcttt ctgaaagtgg cggatttttt gcctttttaa aattttattc taaaatttac
    35581 tctatttgtg ggtgttttgt gcgtttttct cttccatccg tttgaagttt tacattccaa
    35641 tggtataatt tctttatcct atcaaatggg ggaagtattt tgaagaaatt aatcgtacta
    35701 tttattttgt ctgcgggact tttgacattg actggctgtg atttgtttgg cggctctgac
    35761 caatcctcgg acgaaacaac cgattcttct gtcttaaaag cggaaaaagc agataccacc
    35821 aacagtgtat atacgctaaa agtacgtaaa gatatggatt tatccgcggg acagttgaca
    35881 tttacagata aaaaaatgga atggacacgc acgtatcaga cacaaggaac tgattcttct
    35941 gaatcatctg aagaaaaaac agtgctgaca gatatcaaga tcactaccaa agatgacgaa
    36001 tatattattt caggaaaaga aaataaaaaa gaaacaacag tcatatttac aaaaatcggt
    36061 aattaccgtt tgaaggatga ggatggcaac atctacagtc tatagtgccg tctgttggat
    36121 cttcttttgt ttctcccctt cttttctgct atagtaaaga agcaagatga ttgtaaagga
    36181 gacgaaatgg atgatcgata gtcctgatta ttgtacatgt aataacaaca aaaatatcca
    36241 tacagaattt aatgaccaag gaagcttgag catatgcgac aactgtcaca aactagtcaa
    36301 agattcattt aaaacatttg aatcttatcc tgttcaaaat tatgtaaaaa gtagaagaag
    36361 ataaacaaat ccaagcaaaa ctcactatgg ctgattttta tgaacttcaa actcagcttc
    36421 ttcctttgat caagcttcat cagtaaaaca aacagtggat catttcagtt tacaaatcaa
    36481 agagtaaaga tttatttatt tcaaatattt gaatataaaa taaccaaacg atagaaaggc
    36541 ttattctaca tcacgtagta atttttcttt cccgtcgttt ggttttttat ttttagccta
    36601 attcttgacc ttttgcatgc tggttatccg taaaatattt tccagcaggc tttccttcca
    36661 attcagctaa tttttcttgg atctgacgga tcaccttttt tgcatcttct ggattttcta
    36721 caaaatcgaa tttatcccca tccacttgta ttttaggaca tacatcaaaa tcttcatacc
    36781 attgattata gcgggtgttc aacgtttcat aataggtata taacgtctca tcgctttcta
    36841 gctgttcata gtcacgccca cgttttttga tacgttctag catcgtgtcc aaagaaactt
    36901 tgatatggac catcaaatca ggccgttttt ttggagcaac atcatctaac tcgtttagca
    36961 tcgtatctaa taagctatcg tactgctgta cttcgatatc cgttacccga cctaaatcag
    37021 cgtttagatg gaacaacagg ctatcttcat agatggatcg gtctagcaca ttgtcatcgt
    37081 tcactaaagc atttttcatt gctaaaaatc gcttgttcaa aaagaagatt tgcaataaaa
    37141 aagcgtactg ctcaggattt gaataaaaga gcggcaatac ttcgttatct tcgacatttt
    37201 cataaaatgg tttagaatca atctcttttg caagcatatc cgtcaaactg ctcttacctg
    37261 caccaatcgt tcctgaaatc aaaatcactg acatacaacc cttcctcttc tataagtact
    37321 cgcctacgta agtttcaaca ggcaatgttt caaaatcata ttcacgtaca gcttggtctg
    37381 attttaaata cgtatggaga ctttgtgtaa tcatcaagtt cgtaggtacc gtctcttctt
    37441 gtacaatgat catcggtttt ttcaacatag ttgccacacc taattcgtaa gccgttcctg
    37501 gatcgattgt ttgatgctca aagtcaagga tagcaacaac aaattctgca tttgtcagtt
    37561 cttccatatc tttttcgtat acttcctgcg cccatccagc gctgaatagt tcataattgc
    37621 tttcttggtg atgacgtgga gagtagaaac ttgtgactgt tttgttttcc tccaacgctt
    37681 tttcgatacg acttactcga tcgatttgct cctctgaaaa aaatggtcct gctaaatata
    37741 tttgactcat tattttgcct ccttcaataa taactgattt ttaatagata ctgctcgtaa
    37801 ttcattgacc agttccaatg gattgttgga aaagattact tgatccaacc attttttatc
    37861 cataaaatcc tcttttgcaa aagtttctaa taattgttgc aagccgctgt aataaccgcc
    37921 aatattcaat attccgattg gcttgtcggg cgtcagaccg attgctatcc aagaaagaag
    37981 ttgtgagaat tcctccaatg tacctagacc tccagggaaa acgaggacag catctccctt
    38041 ttcaaataat aatacctttc tttcatcgat cgtttctgta ggaataaatg tagtaacatc
    38101 ttttccaggc aattcagttt caaaaagccc attcggatag atacctgtga cttttccgtt
    38161 attttccagt actgttttac taatcactcc cataatcccg gagtatgaac caccgtaaac
    38221 cagttcgatt tcttcttgtg ccatgtattt tcctaacgtt tgcgcaataa atttgtaact
    38281 ttctttatta ccaaaacggg aaccgcaaaa aacagtaagt ttcataaaaa aacactccct
    38341 aactcaaaag tctatcttca ttctacacgt gtttttttaa aataaaagac tagattttgt
    38401 agttttttag tggtatatag gatagacgcc actatatata gtatttagaa aaaa
//
LOCUS       DAFLVO010000021        36463 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.021, whole genome shotgun sequence.
ACCESSION   DAFLVO010000021 DAFLVO010000000
VERSION     DAFLVO010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36463
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.021"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            1046..1360
                     /locus_tag="L1U99_001111"
     CDS             1046..1360
                     /locus_tag="L1U99_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211667.1"
                     /translation="MADENKVVPLETLVINKEEFEQLFLDFFVQYDRIYDFSSSLDLF
                     ELEAEIIENSREENGKIIISVEKFNELFSETFEIDTDYYQPQEVFQSFRNQIIRSGKT
                     VN"
     gene            complement(1413..2186)
                     /locus_tag="L1U99_001112"
     CDS             complement(1413..2186)
                     /locus_tag="L1U99_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211668.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSDTSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAQLYTEKVEQFFEAGANKDFSKISDYSDNFFNETQDEITNSTFMA
                     EDMYNMKLKKIKSYDYPLNLTLNKGILSFVLAGYVDYEYTADYLETPLQHDNNDINFR
                     FIYNSKSKTWLVDQLSTINTGFHELPKPDNETALVIKTF"
     gene            2291..2536
                     /locus_tag="L1U99_001113"
     CDS             2291..2536
                     /locus_tag="L1U99_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1211669.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRVRLEKGIGQTELIRDLQLRKIA
                     ITRETLVKIEGGRQHIKLDQLKAIKDILQVSYEDLLQ"
     gene            2692..3543
                     /locus_tag="L1U99_001114"
     CDS             2692..3543
                     /locus_tag="L1U99_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HBN1211670.1"
                     /translation="MYKAYELDFTNADLNAFSSSSQSYTHVVNQIDHNQKSINKRIEN
                     LFESENDLVDYYSKDSKILDADEIIKDWFPTIKADIFISHSHADEKLAIRFASWLFEN
                     FGLTAFIDSSVWGYSSDLLKKIDQKYCYKEQTKTYDYDKRNVTTSHVHMMLSTALNNM
                     IDSTECLFFLNTPNSISLSNEITNEQKFTYSPWLYSELTTASIVEKKNPRLESNPQMS
                     TEDVRSIIKHYSSQENLQIKYSLNLSELTYLRKADLKKWALDAVECTKGSNTLDILYK
                     NTIFTNL"
     gene            3576..4250
                     /locus_tag="L1U99_001115"
                     /pseudo
     CDS             3576..4250
                     /locus_tag="L1U99_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
     gene            4507..4695
                     /locus_tag="L1U99_001116"
                     /pseudo
     CDS             4507..4695
                     /locus_tag="L1U99_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604486.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            4741..5706
                     /locus_tag="L1U99_001117"
     CDS             4741..5706
                     /locus_tag="L1U99_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1211671.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKNLTLKAKGLLSQMLSLPEDWD
                     YTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDAKGKMADMVYTIYEQPVLENP
                     VLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLSKKEKIITDGQSTHSIPIPSP
                     TPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEYAYLIQDRSIDREQLDEIVDL
                     MLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRFVLDCLRENTTKVRNIKQYLR
                     AMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYSCGEGESL"
     gene            5728..5940
                     /locus_tag="L1U99_001118"
     CDS             5728..5940
                     /locus_tag="L1U99_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBN1211672.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            6015..6491
                     /locus_tag="L1U99_001119"
     CDS             6015..6491
                     /locus_tag="L1U99_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HBN1211673.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            6488..8296
                     /locus_tag="L1U99_001120"
     CDS             6488..8296
                     /locus_tag="L1U99_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBN1211674.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            8373..8588
                     /locus_tag="L1U99_001121"
     CDS             8373..8588
                     /locus_tag="L1U99_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HBN1211675.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            8680..9543
                     /locus_tag="L1U99_001122"
     CDS             8680..9543
                     /locus_tag="L1U99_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211676.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            9580..10116
                     /locus_tag="L1U99_001123"
     CDS             9580..10116
                     /locus_tag="L1U99_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HBN1211677.1"
                     /translation="MSTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVERL
                     ASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTRGN
                     AEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFARQK
                     TPGWDVWGNEVECDLILT"
     gene            10130..10552
                     /locus_tag="L1U99_001124"
     CDS             10130..10552
                     /locus_tag="L1U99_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBN1211678.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            10482..12881
                     /locus_tag="L1U99_001125"
     CDS             10482..12881
                     /locus_tag="L1U99_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBN1211679.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            12913..14904
                     /locus_tag="L1U99_001126"
     CDS             12913..14904
                     /locus_tag="L1U99_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBN1211680.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            14927..15178
                     /locus_tag="L1U99_001127"
     CDS             14927..15178
                     /locus_tag="L1U99_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HBN1211681.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            15168..16397
                     /locus_tag="L1U99_001128"
     CDS             15168..16397
                     /locus_tag="L1U99_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HBN1211682.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            16394..18475
                     /locus_tag="L1U99_001129"
     CDS             16394..18475
                     /locus_tag="L1U99_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBN1211683.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            18624..22544
                     /locus_tag="L1U99_001130"
     CDS             18624..22544
                     /locus_tag="L1U99_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HBN1211684.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKTD
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLIERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            22545..23489
                     /locus_tag="L1U99_001131"
     CDS             22545..23489
                     /locus_tag="L1U99_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211685.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            23493..23696
                     /locus_tag="L1U99_001132"
     CDS             23493..23696
                     /locus_tag="L1U99_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HBN1211686.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(23996..24232)
                     /locus_tag="L1U99_001133"
     CDS             complement(23996..24232)
                     /locus_tag="L1U99_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1211687.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(24415..24801)
                     /locus_tag="L1U99_001134"
     CDS             complement(24415..24801)
                     /locus_tag="L1U99_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HBN1211688.1"
                     /translation="MDARAMSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECI
                     CVQSISYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAA
                     CSKRMRRRKEAERQRKRYWKPTHLEL"
     gene            complement(24783..26111)
                     /locus_tag="L1U99_001135"
     CDS             complement(24783..26111)
                     /locus_tag="L1U99_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBN1211689.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(26072..26401)
                     /gene="mobC"
                     /locus_tag="L1U99_001136"
     CDS             complement(26072..26401)
                     /gene="mobC"
                     /locus_tag="L1U99_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBN1211690.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(26659..27029)
                     /locus_tag="L1U99_001137"
                     /pseudo
     CDS             complement(26659..27029)
                     /locus_tag="L1U99_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            27174..27359
                     /locus_tag="L1U99_001138"
     CDS             27174..27359
                     /locus_tag="L1U99_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBN1211691.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            27517..27684
                     /locus_tag="L1U99_001139"
     CDS             27517..27684
                     /locus_tag="L1U99_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211692.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            28302..28961
                     /gene="vanR"
                     /locus_tag="L1U99_001140"
     CDS             28302..28961
                     /gene="vanR"
                     /locus_tag="L1U99_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HBN1211693.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            28964..30325
                     /gene="vanS"
                     /locus_tag="L1U99_001141"
     CDS             28964..30325
                     /gene="vanS"
                     /locus_tag="L1U99_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBN1211694.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPNFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLT
                     STL"
     gene            complement(30416..31717)
                     /locus_tag="L1U99_001142"
     CDS             complement(30416..31717)
                     /locus_tag="L1U99_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBN1211695.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
     gene            31996..32802
                     /locus_tag="L1U99_001143"
     CDS             31996..32802
                     /locus_tag="L1U99_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HBN1211696.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            32820..33527
                     /locus_tag="L1U99_001144"
     CDS             32820..33527
                     /locus_tag="L1U99_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBN1211697.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGETFSFWLFLHTP
                     LTIIQRRGHEVKEFPEPNSDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKII
                     GQVFADKEPQALYKITNGSIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKC
                     KICYPLPESVDIQEENQ"
     gene            33524..34495
                     /locus_tag="L1U99_001145"
     CDS             33524..34495
                     /locus_tag="L1U99_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HBN1211698.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVSHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            34488..35516
                     /gene="vanB"
                     /locus_tag="L1U99_001146"
     CDS             34488..35516
                     /gene="vanB"
                     /locus_tag="L1U99_001146"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HBN1211699.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKAAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            35522..36130
                     /locus_tag="L1U99_001147"
     CDS             35522..36130
                     /locus_tag="L1U99_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HBN1211700.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(36196..36369)
                     /locus_tag="L1U99_001148"
     CDS             complement(36196..36369)
                     /locus_tag="L1U99_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211701.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
BASE COUNT         9778 a         8760 c         9411 g         8514 t
ORIGIN      
        1 gaaataaaat caaataatta ggaagaaaaa acaaagcaat tagaaaagcc tgcaagcaaa
       61 tttgagtaat cgagatccaa tttttttaag gaagtttaac aaaaatatgt aattctatta
      121 tcactattaa agagaaagtt ggagcggaat ataaagaaaa gagaaaagta attaaacgca
      181 aaaaaatgta gaacttaaaa aatataaaga ggaacaaccg ttaaaattag gaatgatgtt
      241 gtgtaaacat tataattgct atgatataaa tgaagtgtta aagaaagcaa atttaaacca
      301 attttgtgaa cagaaaagcc ttagtcacta tgaccaaaac tacggacgaa actatgacca
      361 aaagtaggta ctaaattatg accgaaaata ggtccaaaat ggattttttt atgatatcaa
      421 aaattatgaa atgattttga aagaaaacca gttggcacag ccaacttagc caccttcctg
      481 taggaaggtg ctatcagttt tcccttatgc tcttttcttt cttttttgtt tcatatgtca
      541 aatgccattt tgaaatgtac catcttaaga aatttatcct taaaaacaat tgcgttattg
      601 gataaaaaga tgctacatta tcttaaaaaa ggaatcaaat atgatgaatt tagtggctag
      661 catatcgtgt gattaagata ctttatagtg taagttgaag gagaaaaaat atttaaaata
      721 tacttcccat ttcagtggga agtaaaatta atcttgttgt ttctactagt aatgtatctt
      781 tttggaaact atgtaacgat gtaaacaaga tttttttcag aagaaaaaac gataaaagtt
      841 gtgataaacg atttaaaaaa taggagaaaa tatatcaagc gcatggtatg aaacgcacat
      901 ttaaaaagat tcgactaact aaaaaaataa gtttacaaag cattgttgtg tattacaagt
      961 gatctataca ctgaaaaatg atagagaaaa tctgatacgt ccgcaacaat ggacaattga
     1021 aaatgaaagt gaggaaattg gaagaatggc tgatgaaaat aaagttgttc cgcttgaaac
     1081 actagtgata aataaggaag agtttgagca actttttctt gatttttttg ttcaatatga
     1141 caggatttat gattttagtt cgtcactaga tttatttgaa ttagaggcag aaataataga
     1201 aaacagtcga gaggagaatg gtaaaatcat catttcagta gaaaaattca atgaattatt
     1261 ctcagaaaca tttgaaatag atacagatta ttatcaacca caagaagttt tccaatcatt
     1321 tagaaatcag attattcgct caggtaagac cgtaaactga aaaacaataa aagaaacgtt
     1381 gaaagaataa ttattccttc aacgtttctt ttttagaatg ttttaatgac caaagcagtt
     1441 tcattgtcag gcttaggtaa ttcatgaaat cccgtattta tagtgctcaa ttgatcaact
     1501 aaccatgttt tactttttga attgtagata aatctaaaat taatatcgtt attatcgtgt
     1561 tgaaggggcg tctccaaata atctgctgta tattcatagt caacgtaacc tgctaataca
     1621 aaagagagta tccctttatt taatgttaga tttaatggat aatcatacga ctttattttt
     1681 ttcaacttca tattgtacat atcttcagcc ataaaagttg agttcgtgat ttcatcttgg
     1741 gtctcattaa aaaagttatc cgaataatcg cttatttttg aaaagtcttt attggcacca
     1801 gcctcaaaaa attgttcaac tttttcagta taaagttgtg ctaacgctcc tttttcaata
     1861 ttaactttaa tattttcatg tctatcaatt tgtgtgctgt tcagtaaggg aagatcagct
     1921 tttagtttta tatcgtcttg atttctttca atttcaattg gcaaaatctt ttcagtagat
     1981 tcagtttctg ataaaggaac atctagtttt ttatcatgat aataagcttc aaatccatct
     2041 ggaaccggaa aaaaatgtat tgggtaattc ttttctgagg ttgttgtact agtttccgta
     2101 cttgtagaac ttgtgtcaga agtggtacac ccgcttatag ttccgatgag taaagcgcaa
     2161 gttagaatga ttgcaaattt cttcaaaaaa attcctcctt aaaattgaat atggactaat
     2221 actagtccca ttgtagcata ccgaatcttt aagattaata agaaaaagga ctaattttag
     2281 tccaaaaggt gtgctattct tgaaagagga aaaaattatt gataaagaaa atgtaatcgg
     2341 tagcaatatt agacgagtcc gattagaaaa aggaattggt caaaccgagc tgattagaga
     2401 cctacagctt cgtaaaattg ctataactag ggaaacgttg gttaagattg aaggtggccg
     2461 ccaacacatt aagttggatc aattgaaagc catcaaagat attctacagg tgtcttatga
     2521 agatttgctt caatgactac ttgtagtcat ttcgtttgaa attattatgt tacaccctta
     2581 tgtgtcacga agaaatactg gtataataat gaatgggata tgtaacgata gggtatactg
     2641 ttatgttgcc taataaattg tggatcaaaa tacaagaatg gagggatatc cttgtataag
     2701 gcatatgaat tggattttac aaatgctgac ttaaatgcat tctcctcaag ctcgcaatca
     2761 tatacacatg tagtaaatca aatagatcac aaccaaaaat ctattaacaa gagaatagaa
     2821 aatctatttg aaagtgaaaa tgatttagtt gattattatt ctaaggacag caaaattcta
     2881 gatgcagacg aaattattaa agattggttt ccaactataa aagcagatat ttttatatct
     2941 cactctcatg ctgatgaaaa attagctata cgttttgcat catggctatt tgaaaatttt
     3001 ggtcttactg catttattga ttcttcggtt tggggataca gttctgattt attaaaaaaa
     3061 atagaccaaa aatattgcta taaggaacaa acaaaaacat atgattatga taaaagaaat
     3121 gtaacaacta gtcatgttca tatgatgctt tctacagctt taaataatat gattgatagt
     3181 acagaatgtc tgttttttct taatacacct aattcaatta gtttgagcaa tgaaatcact
     3241 aatgaacaga aatttacgta ttcgccatgg ctatatagcg aactgacgac agcttcaata
     3301 gtggaaaaaa agaatccacg attggaaagt aatcctcaaa tgagcaccga ggatgttaga
     3361 agcattataa agcactattc ttcgcaagaa aatctgcaaa taaaatattc tttaaattta
     3421 agtgaattaa cttatttacg aaaagctgat ttgaaaaaat gggctttaga tgctgtggaa
     3481 tgcactaaag gaagtaatac attagatatt ttatataaaa acaccatttt cactaatctc
     3541 taatcaattt actgaatcga aaggaaccgg gtagaatgga taagaaagtt ttaataaaga
     3601 ggttctctga agctattgaa aaaggaaatg cagcaatatt tgcaggtgca ggattatcga
     3661 tgtcacaagg atatgtaagt tggccggaac tacttaatga tcctgcaaca gaaatcgggt
     3721 tggattctaa aaaagaaaca gacttagtta ctctggctca atattataaa aatgaaaatg
     3781 gtggatcaag aggaattttg aatcagatac ttatggataa ttttggtgaa gaattagaaa
     3841 tatctgaaaa tcatcgaata ctagcaagtt tacctattga aacttattgg acaactaatt
     3901 atgatcatct aatagaaaaa tcaatccgag aagcttataa aaaccctcag gttaagaaaa
     3961 attatactca gttagcaaca actaatccaa atgtggatac aattgtttat aaaatgcatg
     4021 gtgatataga tgatgtcagt tcgacagtaa taacaagaga tgattatgaa aaatatgatg
     4081 attcgtacgc gttatttaaa gaaactttaa aaggagattt gttaacaaaa acttttctct
     4141 ttttaggatt tagttttaca gaccctaatt tagaaagaat tttatcagat ataagatggg
     4201 ttttgagaga aaaccaaaga cctcattatt gtataatgag aaaaatatta tagaaaaaat
     4261 tttaggttat cgctgaaagc cccggaaata cgggcatttc gcaggatatg agaactcaat
     4321 ttactaccaa tttactactt tcggattgag ccgcatatat gctgaaccat actgctaata
     4381 cccgccaccc caaatacggc acatcataaa ttgaatacga caccgtaaac gcggcgttcc
     4441 tctttcccgt catgggagaa caggacgccg cttttttatg cccaaataga gaaaggaggc
     4501 gacgccatgc tatttacttc cggccctgac cgggcgtttg aacggctgat gcaggaaaag
     4561 cccggtttcg atcactacga cggcggcggg gcggacgcgc cggaggattg cggcacctgc
     4621 cgattttacc gcccggattg gaaatatcaa ttctgccagt ttgcagagtg tccctatcag
     4681 ccgggcaagc tgaccgacta tgcagcggtc aaattcacag tgaaaggagc gaacaacgct
     4741 atggcagttt tccgtgtgga aaagaacaaa ggctatacgg tgatgtcaaa tcaccacctg
     4801 cggaataaga acctgacctt aaaggccaag ggcctgctgt cgcagatgtt gtccttgccg
     4861 gaggattggg actataccct aaaaggactg tcctatatca accgggaaag catcgacgcg
     4921 atcaggacag cggtatggga gcttgaaaaa gctggatata tccggcgtga gcagggccgt
     4981 gacgcaaaag gcaaaatggc cgatatggtc tataccatct acgaacagcc ggtattggaa
     5041 aacccggtat tggaaaatcc aacatcggat aacccggtgt tggaaaatcc gacatcggat
     5101 aatccggcgt cggaaaatcc aacgcaatta aataaagaag tacaaagaac tgacttatca
     5161 aaaaaagaaa aaataattac agatggacaa agtacccatt ccattcctat cccatccccg
     5221 acccctgccc ctatggaggg cgaggcagcg gctacgccgc cggaacggaa aaggacagga
     5281 aaggatgagg ctgtacggat ttatcgggaa atcattttgg agaacatcga gtatgcctat
     5341 ctcattcagg acaggagcat tgaccgtgaa cagcttgacg aaatcgtaga cctgatgctg
     5401 gaaaccgtct gcaccgcccg aaagacaatc cgtgtcgccg gggacgacta ccctgccgag
     5461 ctggtgaaat ccaagtacat gaagctgacc ggcgaacata tccgctttgt ccttgactgt
     5521 ctgcgggaga acacaacgaa agtccgcaat atcaaacaat acctgcgggc tatgctgttc
     5581 aacgccccca gcaccatttc caactactac acggcccttg tcgcgcacga catggcacag
     5641 cccgattggg gaaagcctaa atccggcctg ccggactatt cctgcggcga gggcgaaagc
     5701 ctgtaacgag aaaaggagga cgaccctatg aagcagggcg cattgatttt tgacgagcga
     5761 acagaccgtt acgacatccg ctttgatctg gccgactatt acggcggcct gcattgcggg
     5821 gagtgtttcg acgtgatgat cggcggcaaa tggaggccca cccgcattga aatggccgaa
     5881 aactggtatc ttgtcggcat ccgggccgac gacctttccg gcctgcgggt gcggatttga
     5941 cctatatcta cctgcggcgt ctggtggttc cgccttagac gccgcttttg actttctgac
     6001 aaggagggat gcgattgcag gaagaagtta ctcaaaagac cattgccctg tccatgaaaa
     6061 cgggcaagct cacggctcaa gtgctgcaag cggcgctgaa aaagtacctg caacaccggg
     6121 ccaagggcaa aaacacgctg caccacggcc agcagagcct aaagcagctt aaaaagcatg
     6181 gggctgatct ctccaacatt gagatcaccg aggccaacat tggagcgttc aagccatgcg
     6241 ccaagaaata cggcgtggat tttaccttac gaaaagataa gaccacccag ccgccccact
     6301 acgttgtgat tttcaaggcc aaggatgcag ataaccttga tctggcgttt cgggagttta
     6361 ccgccaagac gctttccaag gagcagcggc cctctatccg caaggttttg tccgctgtga
     6421 agcaaaaggc ggcggcccag accaagcagc gggccaagga gaaaatcaag gaaagggggc
     6481 tggaactgtg aagcctgacg taaagaaatt gctgatcctg aacctcccgt atctgatttt
     6541 tgtgtacctg tttgcgaaat gcggggaggc gtaccggctg gccgctggtg ctgacctgtc
     6601 ggggaagctc ctgcattttg cggatggttt tgcggcggct tttgccaacc cgctgccaag
     6661 cctgcacctg tttgacctgt gtatcggtat cgccggtgcc gtgatcgtgc ggctggtggt
     6721 gtactgcaag agcaagaacg tgaagaaata ccgcaaaggc atggagtatg gcagcgcccg
     6781 ctgggggacg gccaaagaca tagcgcctta catcgacccc aagtttgaaa ataatatcct
     6841 gctcacccaa acggaacggc ttaccatgac cggcaggccc aaagacccca agacagcgcg
     6901 gaataaaaac gtgctggtga tcggtggcag cggttcaggg aaaacgagat ttttcgtgaa
     6961 acccaacctg atgcaatgct ttccgaccac ggactatccg acttcgtttg tggtgacaga
     7021 tccgaaaggc actttggttc tggaaaccgg caggatgttc cagcaggcgg gctaccgcat
     7081 taaaatcctg aataccatta acttttccaa gtccatgaag tacaacccct ttgtctacat
     7141 ccattcggaa aaggacgtgc taaagctggt aaataccctg atttccaaca ccaagggcga
     7201 gggggaaaag tcagcggagg atttttgggt gaagtcggaa cggttgtttt attcggccct
     7261 gatcggctat atctggtacg aggccccagc ggaggaaatg aacttctcaa cgctgctgga
     7321 aatgataaac gccagtgaag cccgcgagga cgacccggag tttcaaagcc ccgtcgatct
     7381 catgtttgag cgtttggagc agaaagaccc cgaccatttt gcggtgcgcc agtacaagaa
     7441 attcctgctg tccgcaggca agacccgttc ttccatcctg atttcatgcg gtgccagact
     7501 tgcgcccttt gacatccggg aggtacgcga gctgatggag gacgacgaaa tggagctgga
     7561 caccatcggg gacgaaaaga cggtgctgta tctcattatg agcgatacgg acacgacctt
     7621 taatttcatt ctggctatgc tccaaagcca gctaatcaac ctgctttgtg accgggctga
     7681 tgatgtgtac ggcgggcggc tgcctgtcca tgtacgcctg attttggatg aatttgccaa
     7741 cattggccaa atacccaatt tcgataaact cattgccacc attcgaagcc gtgaaatatc
     7801 ggcctctatt attttgcaga gccagtcgca gctaaaagcg atttacaagg acgccgccga
     7861 gatcatttcg gataactgcg atagtgtgct tttccttagt gggcgcggca aaaatgccaa
     7921 ggagatttcc gatgcgctgg ggaaagaaac gattgacagt ttcaacacca gcgagaaccg
     7981 gggaagccaa acgtcccacg gattgaacta tcaaaaatta ggaaaggagt tgatgtccca
     8041 agacgaaatt gccgtgatgg acggcggcaa gtgtatcttg cagctacggg gtgtgcgccc
     8101 gtttttatcg gagaaattcg atattaccaa gcatccccgg tacaaatacc ttgccgacgc
     8161 cgacaagaag aatacctttg acgtggacag atttttgact atcacgcgcc ggaaacggca
     8221 gcaagtggta acgcaggatg aagtattcga cctgtatgaa atcgacctgt cggacgagga
     8281 cgccgccgct gaataaacag cggctttttt cattccaaca acaaaatcaa aaaatcatta
     8341 tgagccggaa accggcagaa agaggtaaat ttatggcatt ttttaattcc gcagttacta
     8401 ctttgcagac tatcgtgatc ggactgggcg gcgctctgtg cgtatggggc ggcatcaatc
     8461 tgttggaggg atacgggcag gacaatccgg gggcaaaatc gcagggtgtc aagcagcttg
     8521 tcgctggcgg cggcgtggcc ctgatcggtg tcactctggt tcccctgctg tccgggctgc
     8581 tgggctgatc ctggcctttg tccctgtcca aacccttaac taatcgcctc cgcgtcctcc
     8641 cggccagacc gggagggcgc gggaaaggag gtgctacccg tgattagtga aatcattgaa
     8701 gaatggataa aaggcatcct catggacggt atcacgggca acctgtccgg gctgttcgat
     8761 acggtaaatg ccaaagtcgg agaaatcgcc gccgacgtgg gacgaacccc gcaggcatgg
     8821 aacagcggta ttttcaatat gctgcacagc ctgtcggaaa ccgtgatcgt ccccatagcc
     8881 ggggccatac tcgcccttgt catgtgctat gagcttatcc agatgataac ggaaaagaac
     8941 aatatgcacg actttgacag ctccatgttc ttccgctgga tattcaaatc cgcgtttgca
     9001 atcctgatcg taacgaacac atggaacatc gtcatgggcg tattcgacgc cacccaaagc
     9061 gtcgtcaatc aaagcgccgg tgtgattatc gggcagacat ccattgattt taacaccctg
     9121 ataccagacc ttgaaagcca attggaggct atgagcgtgg gcgctctttt ggggctgtgg
     9181 ttccaaaccc ttgttgtggg cctcaccatg aatatccttt ccatctgcat tttccttgtg
     9241 acctatggcc gcatggtgga aatctatgtt gtcacgtcgc tggggcctat cccccttgcc
     9301 acaatgggca acgcggaatg gcgcggcatg ggccaagggt atctgaaatc cctgctggcg
     9361 ctgggcttcc aagccttttt aatcatggtt gtggtgggta tctacgcggt gctgatacag
     9421 aatatcggtt ccgcttccga catatccggc gcaatctggg gctgtatggg ctatacggtg
     9481 ctgctgtgct tctgcctgtt caagaccggc agtatatcaa aggccgtatt cggggcgcat
     9541 tgatcccaaa atccaagcat acacaggagg aacttgttta tttcaacgta caacatcatt
     9601 tacgctgacc cgccgtggcg gtatgactgc aaaaacgtac agggcgcagc ggaaaatcac
     9661 tattccacca tgagcattga cgagctgtgc gccctgccgg tggaacggct ggcgtccaaa
     9721 gactgcctgc tgtttttgtg ggccacattc cccatgctgc cggaagctct gcggttaatc
     9781 aaagcgtggg gcttttcatt caagaccgtg gcttttgtat ggctgaaaca gaaccgtaaa
     9841 agccttacat ggttttacgg gctgggccgc tggacaaggg gaaacgcgga aatctgcctg
     9901 ctggcaacac acggcaagcc gaagcgtcgt tctgcctctg tccatcagtt tattatcagc
     9961 ccgattgaac aacacagcaa aaagccggat gtgacccgtg aaaaaatcgt agagctggcg
    10021 ggcgatttgc cccgcgtgga gctgtttgcc agacagaaaa cccccggctg ggacgtgtgg
    10081 gggaacgagg tggaatgtga ccttatcctg acgtgaaagg aggtgccaaa tggcttatgt
    10141 aaccgtcccc aaggacttaa cccatgtgaa aagcaaggtt gtgtttgggc ttaccaaacg
    10201 gcaactgatc tgtttttccg gggcgctggt gatcggcgtc cccttatatt ttctcacccg
    10261 tgactatctt accaacagcg cggcggccct gctcatggta tttgccatgc tgccgggctt
    10321 tttgcttgcc atgtacgagc gtcacggcca gccccttgaa gtggtgatta tgcagatcat
    10381 ccagtgctgc ttcatccagc caaaggagcg tccctatcag accgacaaca cctacaccgc
    10441 ccttgtgcgg caataccaga tggaacagga ggtaaaggcc attgtccaaa aaggaaatcc
    10501 caagagaaac cgaaaaaaca aagctgaccc gcgcccagcg aaaagaaatt gacgcggtaa
    10561 tccgtaaata taagggcgac ggcaggcccc acacggcgca gcagagcatc ccctacgagg
    10621 tcatgtaccc ggacggcgtg tgccgggtat cgcccggcgt cttttccaag tgcattgagt
    10681 ttgcggacat cagctatcag cttgcccagc cggacacgca gacggctatc tttgaaaaac
    10741 tgtgcgacct gtataactat gtggacgcct ccattcatat ccagttttct ttcctcaatc
    10801 ggaaagttga cccggtgcag tacgccaaga gctttgagat cgcgccgcag ggggacgact
    10861 tcgacgacat ccgggccgag tacaccggca ttctgcaaaa gcagcttgca aacggcaaca
    10921 acggcatggt aaagaccaaa tacctgacat tcaccatcga ggccgaaagc gtgaaagcgg
    10981 cgcgagccag attgaagcgc atcggctttg acctgttagg ctatttcaag agcatggggg
    11041 ccgtagccca tgtgatggac ggctgggaac ggctgaacct gctgcatggc gtgtaccacc
    11101 cggacggcga gatattcaat tttgactgga agtggctggc cccgtccggc ctctccacca
    11161 aggattttat tgccccgtcc tccctgtgct tcggcaatgc aaagacattc ggcatgggcg
    11221 gcaaatacgg cgcggtaagt ttcctgcaaa tcctgtcccc ggagctgtcg gacgatatgc
    11281 tggccgactt cctcaatacg gaaagcggtg ttttagtcaa tctccatgtg caggccattg
    11341 aacagaccaa ggcgatcaag accatcaagc gcaaaattac cgaccttgac gctatgaaga
    11401 ttgcggagca gaaaaaggcc gtccgcagcg gttacgatat ggacattctt cccagcgacc
    11461 ttgccaccta cggcgaggac gccaagaagc tgctgacaaa gttgcagacc cgcaatgaac
    11521 ggctgttcca gttgacgttc cttgtcctca acgtggccga caccaagcaa aagctgaata
    11581 acgacgtgtt ccaagccgca ggcgtggccc aaaagcataa ctgtcccctt gtccggctgg
    11641 actaccagca ggaacagggc cttgcaagca gcctgccgct gggcgtcaat cagatcaaga
    11701 tacagcgcag ccttacgact tccagcgtgg ccgtgttcgt cccctttgtg acgcaggagc
    11761 tttttcaggg cggcgcggcc atgtattacg gcatcaacgc caagtcccgc aacatgatta
    11821 tgctggacag gaagcaggcc cgttgcccca atgccttgaa gctcggcacc cccggcagcg
    11881 gcaaatccat gagctgtaaa tccgagatcg tcagtgtgtt cttaacgacg cctgacgata
    11941 tttttatttc agacccggag gccgaatatt acccccttgt caaacggctc cacggacagg
    12001 taatccggct gtcgcctacc agcaaggact ttgtgaaccc gctggacatc aacctgaatt
    12061 attcggagga cgataacccg ctggccctga aatccgactt tgtgctgtcg ttctgtgagc
    12121 ttgtcatggg cggcaagaac gggctggaag ccattgaaaa gaccgtgata gaccgggctg
    12181 tgcgcgtgat ctaccggccc tatctggcag acccccgccc ggagaatatg ccgatcctgt
    12241 ccgacctcca caaagcgttg ttagatcagc atgtcccgga ggctgaccgg gtggcgcagg
    12301 cccttgacct gtatgtgtcc ggctccctga acgtatttaa ccaccgtacc aacgtggaca
    12361 tcggcaaccg gcttgtgtcc tttgacatta aggagctggg caagcagctc aaaaagctgg
    12421 ggatgctcat tgtccaagac cagatatggg ggcgcgtcac ggccaaccga agccaaggaa
    12481 aggccacatg gtattttgcc gacgagttcc atttgctttt gaaagaggaa cagacggcgg
    12541 cctattctgc ggagatttgg aagcggttta ggaaatgggg cggcattcca acaggtgcca
    12601 cccagaacgt caaagacctg ctttcctccc cggaaattga aaatatcctt gaaaacagcg
    12661 acttcattac gctgctcaat caggcgtccg gggatagaaa aatccttgcg gaacgcttga
    12721 atttgtccac cgaacagcag aagtacatcg acaattccga acccggcgag ggccttttga
    12781 tctttgaaaa cgtggtgctg ccctttacca accccatccc gcacaacacc cagctttaca
    12841 agattatgac gacccgctta aacgaggtgg cgggagtatg acccggcgac gccacaaagg
    12901 aggtgaacca ccatgaaaga gctgaaagcc aaggcgaaag tgacgcaggc catgacccgc
    12961 gacgggctga cgctggaaaa tcaggccacc ggcgaggtgg agaacatttc cagccgggag
    13021 gccgaacagg atttgtccgc gccggggccg ggcggcaccg ccgataagct gctggaacgg
    13081 gccgacgcca tccatgacgg ccataaggcc aagaaagccg cgaagcaggc cggggctgtg
    13141 gccgccgagg gggacgctgc cctgcaccgg ccatccgccc ggctccaact gtcggaggaa
    13201 gaacgggccg acccggattt acagccctat atccgaaaat cggacaaacg ggccgataag
    13261 ctggataagg cccgcgccgc catccccaag aagcgcgtcc cggtcaagga aaccgtcttt
    13321 gacgaggcaa gcggcaaagc aaagaccgtc ctgcactttg acaaacagga caaggggcct
    13381 ccctccctga aacccaatcc ggcaggccgt cctgtttccg aggtttttct attcggccac
    13441 gggaaaatcc atgaagtcga gcatgaaaac gtgggtgtgg agggcggcca taagggggag
    13501 gaacttgccg agcggcaggc cggaaaagcc atccgcagca ccatccggca ccacaggctg
    13561 aaaccctact gggacgcgga aaaggccgag cgcaggctat tgtctgccaa cgcggagtat
    13621 ttctaccaga aatctttgcg ggataacccg gagatcgcac aggcggccag caaccccatt
    13681 tcccggttct ggcagaaaca gcagatcaag cgccagtacg ccaaggccgc ccggacagcg
    13741 ggccagaccg caggcgcggc ggcacagggc gcggccaaga cagccggggc ctccacgaaa
    13801 gcggccaagg ccgcagccaa agaaagtgaa cgggcggcct cctttgtggc ccgccactgg
    13861 aaaggggcgc tggccgtcct tgtgttgggg cttttgatgc tgcttatcat cggcggctta
    13921 cagtcctgca ccgccatgtt cggcagcgcc ggaagcggca tcacggcgtc ctcttacttt
    13981 tccgaggata gcgatatgtt ggccgccgag gacgcctacg cggagctgga agccgagctg
    14041 caagactatc tggacaacta cgaggccacc catgactatg acgaatacca ttttgacctt
    14101 gacgagatca gccatgaccc ctatgtgctg atttccattc tgtcggcgct ccatgacggg
    14161 atatttacca tcggggaggt acagggtgat ttgtccatgc tctttgacaa gcaatatatc
    14221 ctgacagaaa acgtcgtggt agaaacccgt taccgcaccg aaaccgatac atggacggac
    14281 gcggagggca acacccatac agacacctac caagtgccgt atgactatta catctgctac
    14341 gtcacgctgg aaaacttcga cctgtcccat gtgccagtct atatcatgga cgaggaaacg
    14401 ctaagtttct attccctgta tatgtccacg ctaggaaacc ggcctgatct gttttccggc
    14461 agccagtacc ccaacgcctc caccctgacg ccgccgacct actacgacgt acccccggag
    14521 gctttggagg atgccacctt tgccgccatg ctcaaagagg cggaaaaata tatcggttat
    14581 ccctatgtgt ggggcggcag ctctcccagc accagctttg attgcagcgg cttcatttcg
    14641 tgggtaatca atcatagtgg atggaacgtg ggacggctgg gggcgcaggg cctatataac
    14701 atctgcaccc ctgtttccag ttcgcaggcc aagcccggcg accttgtatt tttcaaggga
    14761 acctacgaca cccccggcgt gtcccacgtc ggcctgtatg tgggcaacaa tgtgatgctg
    14821 cattgcggga acccgatttc ctacacgaac cttacttcaa actactggca atcccatttt
    14881 tacagttacg ggcgtttacc ttaacgccag aaaggagctt tcaattatgg caaccaaact
    14941 tgaccgcatc gaaaaggaca tccagaaaac caagtctaag atcgcggagt ttcagaaaca
    15001 gcttcgggag ctggaaacgc agaaaaccga acaggagaat ttgcagatca tccagcttgt
    15061 gcgcggcatg aacatgaagc cggaggaatt tgccgcgttc ttacgcagcg gcgcaatgca
    15121 ggccgcccct gccgcaaccc cttaccatga acaggaggac aatgcccatg aagaataaga
    15181 ccagacggat ttcccgtatt ctccccgcac ttctggccgt gatgctctgc gtcacggcct
    15241 ttcccgttac cgcccttgca ggcggcaatg acccggcacc ggccccgctg ccggaggcta
    15301 caaccgaacc cgctacgggc ggtttggagc ctgaaacaga cgaaaccggc accgccacgg
    15361 acgggacaga aaccgaggcc gaaaaagata ccggccctct gaccggcaag gacatcaccg
    15421 acctgttttc cgcgctgttc ggttccaagg tgagcattgc cgccacggac gacggcatcc
    15481 agatcaccac cggcaccgac aaaaaagaac ctgaacagac cggcaccgtc accaccaacg
    15541 gcggcaggct gaatgtccgc accggcgcgg ggcttgacaa gaccgcgttc acccagcttc
    15601 ccaatgggac gacggttgag gtagtcggca cagacggcga ctggattaaa attctcttgc
    15661 cggagcgcat cggctatgtc cattccgact atatgaccgt cagcgaaaag gaagtagcgg
    15721 ctaccggcga gggcggtttt tccctctcca ttgacccgga ggaaattgct tctctgctgg
    15781 aactgttcaa tggcggcggg gccagcgccg ccctgtcccc ggacgggaac ctgtcactga
    15841 ttgacgacat cggcagcgcc gcgaaaaatg gcaagcagtt tatcaccgtg gaaaccaaaa
    15901 acggcaatgt gttttatctg attattgacc gggacgacga gggaaaagaa actgtccatt
    15961 tcttaaatca ggtggatgaa gccgatctgc tgacgctgat ggaggacggg gaaaccgtca
    16021 cccccgctgc tgtctgctcc tgtaccacga aatgcaaggc cggggctgtg aacacgaatt
    16081 gcccggtatg taaaaccaac ctgaccgagt gcagcggccc ggagccgcag gaaccccagc
    16141 cggaggaacc cgaagccccg gaggaagaac ccaagggcgg cgcgggcggc ctgatcgtgt
    16201 tcctgctggt ggcgctggcg ggcggcggtg cggcccttta ctatttcaag ttcaaaaagc
    16261 ccaaggctga aaccaccggc agcgacgatt tgggcgagta tgattttggg gaggacgagg
    16321 atttggagga cgaggaaccc gaaaccgagt ttgacccgga agctgatttt gtgagtgaac
    16381 aggaggacga ggaatgacat ataaacttgt aatcgcggaa aaacccagcg tggcccgcag
    16441 cattgcgggc gtgatcgggg ccacggagaa acacgacggc tatttggagg ggaacggcta
    16501 tctggtgagc tggtgcatcg gacatctggt gtcctttgcc gacgccggac gctatgacga
    16561 gcgtttcaaa aaatggcgct atgaggattt gcccattctc ccggaaacat ggcagtacat
    16621 cgtccccgac gacaagaaac agcagtttga cgttctctgt tcgctgatgc agcgccccga
    16681 cgtgaccggc cttgtgtgcg ccaccgacgc cgggcgcgag ggggaattga ttttccgttt
    16741 cgtctaccag atggcgggat gccaaaagcc ctttgagcgc ctttggattt cctctatgga
    16801 ggacagtgct attaaggacg gctttgccca cctgaaaccg ggcggcgact atgatccgct
    16861 gtatcaatcg gccctgtgcc gggccaaggc cgactggctg atcggcatta acgccacccg
    16921 gcttttttcc gtcctgtacc acaagaacct gactgtgggc cgcgtccaga cgccgacctt
    16981 aaaaatgctg gtggacaggg acgccaagat taccgatttc aagaaagaga aatatcacat
    17041 cgtccatatc acggcgggcg gcgcggacgc ggtaagcagc cgcttttccg acgctgccga
    17101 ggcaaacacc gtcaaggcgg cttgtgcaaa agcgcaggcc gtttgcgttt ccgtgacgcg
    17161 ggagaaaaag acggaacagc cgcccaagct ctatgacctt accaccttgc agcgggaggc
    17221 taaccggctt ttcggctata ccgccaagca gacccttgac tatgcccagg cactgtatct
    17281 aaagaagctg ctgacctatc cgagaacgga tagtcaatat cttaccgacg atatgctgcc
    17341 cgccgtggaa agccttgtgt ccggcctgtg ggagctggtg ccgtttgcca agggcctgaa
    17401 cctttccccg cagtttgacc gcatcctgaa cagcaaaaag gtgtccgacc accacgccat
    17461 tatccccacc gctgaatttg tgaagcaggg ctttggcact ctggccgaga gtgaaaaaaa
    17521 gctgctgtcc ctgatctgct gcaagctctt atgtgccgtg gccgggccgc atatctatga
    17581 ggccgtcacc gccacattta cctgtgccgg gcaggagttt accgccaagg gcaagaccgt
    17641 cctttccccc ggctggaaag agattgaacg ccggttccgt tcttccttaa agaccgacgc
    17701 cgacgaggac gccgaggcgg tgcgggagct gccggagctt tgcgagggcc agacctttgc
    17761 agacgtggcc gcctctgtca ccgagcattt caccacgccg cccaagccct acaccgaaga
    17821 tacgcttttg tccgctatgg aacgggccgg ggccgaggat atgccggagg atgccgagcg
    17881 caagggatta ggcacaccgg ccacccgcgc cgccattctg gaaaagctgg tgcagatggg
    17941 ctttgtccag agaaaaggca agcagctcat tcccaccaag gacggcatca atctggctgt
    18001 ggtgctgccg gaggcgctta cttctcccca gcttactgcc gaatgggaaa accggctgac
    18061 cgagatcgcc aaggggcagg ccgatcctga cgaatttatg gacggcatcg agacgcaggc
    18121 gcgggagctg gtgcagacct attcctgtat cagtgaggaa aagcagaaat tgtttcaggc
    18181 cgagcgtgtt cctatcggga cgtgtccccg ctgtggtgag gctgtctatg agggcaagaa
    18241 aaactactac tgcggaaacc gggcctgcca gttcgtcatg tggaagaatg accgattttt
    18301 tgaggaacgc aagaaagcgt tcaccccgaa gatcgccgct gcgctgctca aaaccggcaa
    18361 agtcaaggta aagggcctct attccgtaaa gaccggcaaa acctacgacg ggacggtgct
    18421 tttggctgat accgggggca agtacgtcaa ctaccgcatt gaacacagga gctaaaggac
    18481 agtaacacag caagcatagg gagtgtggct acactcccgg taaaatcccc cggccgcgtc
    18541 cctgccgggc cggggatttt tgcttgttgg ggaagtcccc aaccccctat tttttgaaac
    18601 agaacagaga aaggagtgac cgcgtgaacg aagtattttc tatccaagtc cataaccggc
    18661 agtttttgga acagggcaaa caaggcgtct ggctggattt gcccaccaca accgaaacgc
    18721 tgcaagccgc cctgcgggat gttggcatta ctgccgacaa tccgcaggat ttttttatca
    18781 acgggtattc ctgcccggag gacagacacc ttgccattcc ctatgacatg gtgctggccg
    18841 ccgacgtgga cgagctgaat ttccttgccg cccggctggg ccagcttgac gccgccgaga
    18901 tcgcagagct gaacgccgcc ctgcaaaatc cccgtggcgg ctttgagaat atcggccaga
    18961 tcatcgacta caccgaaaat gtggattact atgtgcatct tcccgacgtt aggggggatg
    19021 gacagttggg cgactactac ctgaaccgtt ccggcatggt ggatatgccg gaggaatgga
    19081 aagccgggat tgatacggcg cagtttggac gccacattgc ccagcaggaa caaggcgttt
    19141 ttacccagta cggctatctg gtgagaagcg gcgacgaatg gcagcgcgtc catgagggcc
    19201 agccggtgcc ggaggaatac cgggtgatgc actaccccca gccggaagct gaccgggagg
    19261 aaccgcaggc ccagcagccg gaggcatccg aaagccccga caaagcgccg cccccggtta
    19321 tcccgatcat gctggacggc atgaacagca aagaacgcat gaaagtgatt actgaccgtc
    19381 tggaaaccgg cgtacaggag ctttttgaaa gtagccgcta tatggcttac ttatccgcta
    19441 tgtccaagat gcacgattac agtctgaaca atacgctgct gatcgccatg cagggcggtt
    19501 cgattgtggc gggctataac aggtggcagg atgaatttga ccgccatgtg aagcggggcg
    19561 agaaaggcat taagatactg gccccggccc cgttcaaggt taagcagcag atggagaaaa
    19621 ccgacccggc cacccagcag cccgtgatcg gcgcggacgg caagcccgtg accgaagaac
    19681 aggaagtgac ggttccggcc tttaaggtgg tgacagtctt tgacatcagc cagaccgagg
    19741 gcaaggattt tcccatgccc tatatcagtg aacttaccgg cgacgtgcag cagtatcagg
    19801 atttctttgc cgcgctggaa cggacatcac cctatcccat aagcattgag ccgatttcag
    19861 acggggccaa gggccgctgc ttctacgcaa aacagcgcat tgccatcaac gagggcatga
    19921 gcgaattgca gaccctaaag accgccatcc atgagattgc ccatgccaag ctccacgcca
    19981 ttgaccggga ggcccccgcc gaggaacagg cggcccggcc agaccgcagc acccgcgagg
    20041 tacaggccga aagcgtggcc tataccgtct gccagtatta cgggctggac acgtcggact
    20101 attcttttgg ctatgtggcc gattggagca gcggcaggga gttatccgag ctgaaagcct
    20161 cccttgaaac catccgggcc acggccagcg aattgataac cgagatcgac ggccattttg
    20221 cccagcttca gcaggagcgc gaggcccggc aggaacagga ggccgtcacg gttgacgtta
    20281 ccccggaggc agcggccccg gcgcaggccg aggaagaaca ggccccggcc cttgatccgg
    20341 cagccgagcc gcttgtgact gtgctatgga gcgaaagccc ccagctaaag gacggccagc
    20401 aaatgccgtt gcatgaggcc gacgcgctgt ttgcccgtct ggatgcagca tatccggcag
    20461 aggcaggcta tgacaaaacc gcgttccgca ttgactgtat ctttcagggc gagccggaca
    20521 gctacgaggg gcggcaggat tttggagata gggacggttc cctgatcgaa catatccaga
    20581 gctaccacca attttacgcg caggacgaaa actggaaaaa gcatgtaatc gctacaaccg
    20641 gcatagaggg ctgggagcag gacaaggccc atcgggatat gctgttaggc gagtttgtcc
    20701 cctatatgaa gctgcattgc agccttgccc aaatggaaca gacggcgcag ggccgcttac
    20761 agtccgggga aaccctgacg ccggaggaaa cggcctattt gggggcgctt ctctcttatg
    20821 tgcaggagtg ccgccccatg ctcaatcagg gccagtatca gttgccggag ccgccgaaac
    20881 tggctgactt cgaccagagc ttgcaggact acaaagcaca ggtacaggcc gagatcgcgc
    20941 aggaggccgc cgcagccggt atgaccgtgg aggaatacgc ggcggctggc tatgaagcac
    21001 cccaacagga caccttttcc atctaccagc ttcgaggcgg ggaggaaacc cgcgactatc
    21061 ggtttgagcc atacgagcgt ttacaggccg cagggctggc cgtggacagt gccaactatg
    21121 accttgttta tacggcaccg ctggataaaa gcacgtcttt ggaggatatt taccgcacat
    21181 tcaacatcga ccacccggca gattttaggg gacacagcct ttccgtttcc gacgtggtgg
    21241 tgctgcacca gaatggacag gacaccgccc actatgtaga cagcttcggc tatatggaag
    21301 tgccggagtt tttgcgggaa aatcccctgc gtaccgccga actgtctacg gagcagaacg
    21361 aaaacatgat tgacggcatt atcaacaata cgccgcccga accgcagccg gaggaacccg
    21421 aacagctatc ttttgaggat gtggcagttg cttccggcca gacacaggag gaacccccgg
    21481 aggctgcgcc cccgcaaacg gctgtccgct attatcccat caatgaggga gccgcccgcc
    21541 gcgccaagga agccatgagc ttttctgact accggcccgg cagcgccacg gcggaatacc
    21601 ggcactatgt cgatcaggcc gtggaaattg cggagcgcca gaaaaagcgt gtggagccag
    21661 agtatcacga aaagatagac agcctccttg acacctacgc ccgcaagctg gccgagaaca
    21721 tgaataaggg ctatgagatt accgcccgcg tcccctctgt cctgattgcc gggccgtcca
    21781 atttcccggt acgggcgaaa gaaaagcaga acgccgccag tgaccgcaac atggaggaat
    21841 ttcagtacat tcagggcttg cttgacaaaa tccgcagcac cggcatgggt ggtatcagcg
    21901 ccgacgatcc gcaggccgtt tccaagctgg aaaagaaact ggaaaagctg gaagcgtcgc
    21961 aggagttgat gaaggccgtc aatgcctact accgcaagca tgggacgctg gacggatgcc
    22021 cccatctgat cgaaagaggc attgaaaacc tgaaagcgga tatggcgtcg ggctggcact
    22081 atgagaaaaa accgttccag tcctggcagc tctccaacaa taacgccgag atacgccggt
    22141 taaagggccg cattgaggaa ttgacccgcc aaaaggaggc ggcctatgtg ggatgggagt
    22201 ttgacggcgg cactgtggag atcaaccggg tggccaaccg cctgcaaatc ttctttgagg
    22261 ggaagccgga tgctgctgta cgcgacgagc tgaaaagcaa cggtttccgc tggtcgccca
    22321 aggccggggc atggcagcgg cagttaaacg acaccacaat ccgcgtcgct gaccgtatca
    22381 agtgcatcca gcccctttcc ggcgaaaagc ccagcgcctt acagcttgcg gcccgcaggg
    22441 agaaagaaaa gccctctatc cgggcgcagc tcaacgcggc caagaccgaa caggccaagc
    22501 agccaccggc gcgggaaaaa tcaaagggat tggaggtaga gtaaatgcag aagtttgaaa
    22561 atgtggacgt tctggccgcg ctggaacaga tcatgcggca gaacaccgcg ttttatcaaa
    22621 gtgactttgg cattgacaaa gacattatca ggcgggatgc cgccagcgat caggccgcag
    22681 acaagaccct gctctggatg tcccggccct ccgggacgta ctgtttccgg gaacgtgatg
    22741 ttttcctgaa agacacccga cagtacaaca catggaaatt ttacggggag cagacccgtg
    22801 acaagatact ggcctacgcg gtggagctga ccggcacaca gggcggcact atccggggca
    22861 atctctatga gctggactat ccgcagcatt tccggcacgt cattgaaacc gcccagccgg
    22921 tgagtgtgaa ccggctcttt tatgagcatg gcacccgtga catcccggag agccagcgtt
    22981 ttgacggaag ccctgaccgg gtattgggaa actttttgta ctatgaggcc cagccccatg
    23041 acccggctgt gctgcaggag gcgctacgga cggagcagca cagccggggg cgggccgtcc
    23101 ccggcgattt caaagtccac gtcaccgctt tgcatgacag ccggattgaa accgaggccc
    23161 ggcgtattgt ggacagcctg aaagatctgt ccgcgcctaa cagccccaat aaaacgcatt
    23221 tcatggtgga gatctccccg cactttgcgg cgattgcttc caccaaggat aatgaccggc
    23281 tctttgccat gctgccctat aaatccctgt gttttaccgg gatgaaaggc aggcatggcg
    23341 tgtatgccgt gattaaccgg gacgagcgcc gggatgtgag tattcgcagg ccccggccct
    23401 ctatccgcaa gcagctatcc gacagcaaac aggccgccag cccaaaaaag gcggcggcca
    23461 gaaccaaaaa gaatgaattg gaggtataag gaatgatgca ctttaccgtg gaggaagaaa
    23521 acctgatctg tatgtaccac aatgcagacc ggcgcagaac gataaacagg ctcaccgccg
    23581 tcatgccggt tatggatggg gatatgcggg cgcaggccca gcagaccctt tccaagctgg
    23641 aacgcatgac ggatgccgac tatgacggcc agaagttcca cttcacagac gaataacgaa
    23701 cagcagacgc cgggcgcggc ggccatgtgg tcgcttgcgt ccggcgtctt ttctttttgc
    23761 ctattcctac gcatttagaa cccggtattg tcggggatag gatgaagtat tcgcttgccc
    23821 ctgcaaacat gcgggagaag ccttgcagcg ggcggttttc aatcccttaa atgcgtaggt
    23881 tgcagctata attagacccc tgaaacagat atagccgcgc agcgggtgta tctgtttcag
    23941 gggtgtgcag gtgatagccg caaagcggcg taagagggtg cagccctctt gccgtctatc
    24001 tctgttccag cgggaagctc ggcaatgctt ccagcagttt cagggaaatg cgctgccgta
    24061 tatcttcgtc aatgactttc ttctttttgc cgtttgcctg tctgatctcc accgtggaaa
    24121 gctcgttgat gtagtcagca taatgggcca acactttttc cgtggcccac ctctcaccgg
    24181 caacggcggc tttgatcgtt tcatagtcca gcagcttttc ttgtccgtcc atcctgatac
    24241 ccccgtcaga ctgatttttt ctatgatacc atattcggaa gcatggaacc agagaaaacg
    24301 gcgcttttct gctggtaaat tctacgcatt tagaacagca cttcggcggg gataggataa
    24361 aacacccaca taccccgctg accatgccgg aaaagccttg aaatataagg gcttttacag
    24421 ctctaagtgc gtaggtttcc agtatctttt ccgctggcgc tcggcctctt tgcggcggcg
    24481 catccgtttg gagcaggccg cgcagtattt ggcccggtta gacttcggcg tgaacgtggc
    24541 cccgcactca cagcagcgtt tcacttcgtc ccggtctttg gtgatctcgg catacagggc
    24601 cgcatccagc gggaggacag cggccttaaa ccagcggcac agaagcgaat aggaaatgct
    24661 ctgtacgcaa atacattctt cgccgtcgtc cagcaacagg cagttgccgt cacaatagtt
    24721 gcagcactca tgcgtcagct tccgggcctt gcgatattga gggtaattca ttcgtggaat
    24781 actcatagct cttgcgtcca ttcctttccc ggcgtcatac gcaaaatgcc gtccacattc
    24841 tgcttgatga tgccgtattc ctgcatctgc tttttcgctt cgccgtactt ctcatacagc
    24901 cgttcctttt cctcggccaa tcgcttgtac tcggctttca gggcgtacag atcggggagc
    24961 tttttcacac cctgtccctt tagggccttt gccgcagctt catacaaaat caacgtgctt
    25021 tcatgctcac gccggaattt tgccttatcc gctgcattgc ggtattccat agccacgggc
    25081 cagagctgct tgtaggtaga aatattcttt atcagcaccg ccatatccgc aagccggtgt
    25141 tccatagctt tgagggtagc ggcggcctcg tcgctggcgg cggtgatctc ggccactttg
    25201 ctttccaaat ccgggtaggt gtctatccca tgttcagtca ggaaattcaa agtctttgcg
    25261 gcctgcttca aattgtggag cttcgcccac ctctcatagc ctgccgactg ctgggcctta
    25321 atgttgtttt ccagatcaat ccgcaaagaa atccccttgc gctctttggg cgctctggtg
    25381 ataacgcggc ctttgatacg ctctttgatg gcttcctcgg tgtaggcttc ccccaatgtc
    25441 ttgcagcggg taaagcgttc ctgtccggga gcgcggaaag aaataaactt tcccggcttg
    25501 atctcatagc cctgcgcctg catgagccgc aggaaatcat caaaatcttt tgcctgcggg
    25561 atagcggcgt caatggctgc tttgagcttc gctttccagc tcgtcccttt ccgctgggcg
    25621 tcccactcgg catagctctt gcccttactc tggccgggct tcaccacgga caatccgttt
    25681 tccttgcaca gcctgtcgct ggtgcgccgg atataggcat agctctgttt gttggaaatg
    25741 tacttgcgct gatttaccat atccacggca cagaaaataa tgtgattgtg gacgtggccc
    25801 ttatcaatat gggtagtcag cacataggga tatttccctt gcagcacttc ctcggcaagc
    25861 tgcttcccga tctcatgggc ctgttccggc gtggcttcgc cgggggcaaa ggattgtatc
    25921 aggtggtggc ccagattatt gcccttttgg tatgcctgcg ccagcagcat ttcaaattca
    25981 atgtccgctg tttcataaga gcaggcaaag gaggccacca gcagcttgcc gtcagttttg
    26041 tccgggttct cgatgtagtc aagggctttt ttcagcgttg acttgatagg atgtatcttt
    26101 gtaactgcca tatctgcgcc agcgccccct ttatatcctc gatgtcctgt gcgtacaccg
    26161 gccccatacc gttcagcctc tttgcaatct gattgacgtt gacgccgatc ttctgtatct
    26221 cggcggtctg cgcccggatg tcgctggtgt ccatgttgac gatatagccg tcaatgagca
    26281 tcttccgggc gtaggctgaa aagttcttcg tatgcagcag cgccattttc tgttcaatca
    26341 tagcccgttc ctccggcgtc acagggacgc gcagcacgat ttttcgcttt ctgtttgcca
    26401 tgcttcaccg tcctttccat tcaggggttt ggggatttcc ccaacaagca aaacggacgc
    26461 ggcccggcag ggacggggca ggccgttttt ccgggagtgg ctacactccc tatgcttgct
    26521 acgttactgt ttctccacta acaagacgtt tccaaagccc caaactaccc gcaaaatagc
    26581 cctctggaaa gaaaaaagtg caaaaaaata gaagctacgc tgtgcagctc ccgctaaaag
    26641 taaaacagag gatgccagtt acacatcctc cgtttcattc ttcttcggct tttcaattag
    26701 tatggcgctg tcaatcgcgc cctcgatgat cggcaggtat tcttcggggc agagtttcag
    26761 cttgtggctg accctttgcc gcagttcgct ttcctcccgc atgatctccg ggttaaagta
    26821 gcgttccaca ggaagcccgc aggctttaat aagctgtatg acaaccggca gactgggaat
    26881 ggcccgtcgt tttcgatgtt ggcaagatag cgccagtcaa tatttatttt ctctgccatt
    26941 gctttgcgcg aaacgcgctt tgcttgccgg gccgctttca catccgcgcc gaaagtttca
    27001 aagccgggac aatcttcaat attcgccata tcgcacctcc cacttacatt gtatatttca
    27061 tactctgccc gtggaatgtt ggtatatgca cctttcttaa agtttatatt tcacattttg
    27121 tttcttttat tcttcgagca aaagaattat aatgtaccct gtggaggtgt actatggact
    27181 acatgacgtt gaaagaggca ggcgagaaat ggggtgtgcc cccacgatgg ataaactact
    27241 attgtgctgc gggacgcatc cccggcgctg taaagatggc gacgatctgg ctcattccca
    27301 aaactgcgga aaagccgatt gacaggcgta caaagaaagg aaaggcggtt actgaatagt
    27361 ataatgaaac cggcgcattt tggatatggt tttgaagaga gagaaagcat ggtattttgt
    27421 cacggaaaaa ctataagatg atagatggca ggctgctcca gaccgataaa aagtattctc
    27481 atctgaaaca gaaagaaaag atttacacat ggatgtatga agaagcgaaa ctttatcatg
    27541 acagaaatgg aaaatgcccg aaacaaagac gaggaagctg ctgctgtatc agccgtatat
    27601 ggtagaattg aaaaggccgg catctggatt ctttatggtg aagtctccag acattggata
    27661 actgctggtc taatgcgcct ttgagtatgg ggtgattgat tttaataccg gggaggtacg
    27721 gctttttgag gaaaatattc tgggatttac atttggcgat tattacattt cctgtaactg
    27781 caaggacacg gatgatgaag atatgaggaa tatagacttg ctgattttct actgtcttga
    27841 acggtattag gactgaatct gctgcgcgga gtgcggcaag agcgaccgga gggagtacac
    27901 acaggccctg cctgtgtgaa aagccatacc gcaaggtgca ttcgcaaaaa agaggccgcg
    27961 cattttgctg aggcttgggg tgtccccaac aagcaaaacg agaacgccgc aggcgggcaa
    28021 gtggtggatc agaatatccg taaaggatat tctgatccat tgcttgccag tattatcggg
    28081 atgttttgac aaccgctgta atcgaaacat cccaaacatt aagaaggtgt taattattat
    28141 tatcttgatt taattcgttt aaaccaataa tatagataca tacaccatga aaagaagcga
    28201 gtatcccaat gacggatgat taaaatccga aaagaaatcg ctttgaaact acagggaaac
    28261 tacagactgt tatgttatct tcttaaaatg gagggatttt tatgtcgata cgaattctac
    28321 ttgtcgagga tgatgatcat atctgtaata cagtaagggc gtttctggct gaggcaggat
    28381 atcaggtgga tgcctgcaca gatggaaatg aggcatacac caagttttac gaaaacactt
    28441 atcaactggt tattcttgat attatgctgc ccggtatgaa cgggcatgaa cttttgcgtg
    28501 aatttcgtgc gaaaaatgat actcccattc tgatgatgac agccctgtcg gatgacgaaa
    28561 accaaatccg ggcgtttgat gcagaggcag acgactatgt aacaaagcca ttcaagatgc
    28621 agattttact aaagcgggtg gaagccctgc tgcggcgcag cggtgcgctg gcaaaggaaa
    28681 tccgtgtcgg caggctgaca cttctgccgg aggatttcac ggtactttgt gacggtacag
    28741 agctgcccct gacacgaaaa gaatttgaaa tccttttgct gctggtgcag aacaaaggca
    28801 gaaccttaac gcatgaaatc attttgtcac gtatatgggg atatgacttt gagggtgatg
    28861 gcagcacagt ccacactcat atcaaaaatt tgcgggccaa gctgccggaa aatatcatca
    28921 aaaccattcg cggtgtagga taccgattgg aggaatcata ataatggaaa gaaaagggat
    28981 tttcattaag gttttttcct atacgatcat tgtcctgcta ctgcttgtcg gtgtaacagc
    29041 aacactgttt gcacagcaat ttgtgtctta tttcagagtg atggaattac agcaaacagt
    29101 aaaatcctat cagccattgg tggaactgat tcagaatagc gataggcttg atattcaaga
    29161 ggtggcaggg ctgtttcact acaataacca atcctttgag ttttatattg aagataaaga
    29221 gggaagcgta ctctatgcca caccaaatgc caatacatca aatagtttta gacccaactt
    29281 tctttatgtg gtacatagag atgataatat ttcgattgtt gctcaaagca aggcaggtgt
    29341 gggattgctt tatcaagggc tgacaattcg gggaattgtt atgattgcga taatggttgt
    29401 attcagcctt ttatgcgcgt atatctttgc gcggcaaatg acaacgccga tcaaagcctt
    29461 agcggacagt gcgaataaaa tggcaaacct gaaagatgta ccgccgccgc tggagcgaaa
    29521 ggatgagctt ggcgcactgg ctcatgatat gcattccatg tatgtcaggc tgaaagaaac
    29581 catcgcaagg ctggaggatg aaatcgcaag ggaacatgag ttggaggaaa cacagcgata
    29641 tttctttgcg gcagcttctc atgagctaaa aacgcccatc gcggctacaa gcgttctgtt
    29701 ggagggaatg cttgaaaata tcggtgacta caaagatcat tctaagtatc tgcgcgaatg
    29761 catcaaaatg atggataggc agggcaaaat catttccgaa atactggagc ttgtcagcct
    29821 gaatgatggg agaatcgtac ccatagctga accgttggac atagggcgca cggttgccga
    29881 gttgctgccc gattttcaaa ccttggcaga ggcaaacaac cagcggttcg tcacagatat
    29941 tccagccggg caaattgtcc tgtccgatcc gaggctgctc caaaaggcac tatccaatgt
    30001 catattgaat gcagttcaga acacgccgca gggaggcgag gtacggatat ggagtgagcc
    30061 tggtgctgaa aaatgccgcc tttttgtttt gaacatgggc gttcacattg atgatactgc
    30121 gcttccaagg ctgttcaccc cattctatcg cattgatcag gcgcgaagca gaaaaagtgg
    30181 gcgaagcaga aaaagtgggc gaagcggttt aggacttgcc atcgtacaaa aaacgctgga
    30241 tgccatgagc ctccagtatg cgctggaaaa cacctcggat ggcgttttgt tctggctgga
    30301 tttaccgctc acatcaacat tgtaaatatt taaaacttaa atgattttgg gctctttgtc
    30361 aaataggact gatagagtga gataagaaca tctaaggtag aattcctttt ctactttaga
    30421 tgttttttga ttcataggta atcagattat ttagtaagaa aattctggtc ttcattttcc
    30481 gaaagcttcg aaagccataa gcgactcgtt tcaatgcttt gatgtgggta tgcagatttt
    30541 ctattttggc atttgaataa ggcaattcga gggctaaacg aatgccggat tcatagttta
    30601 taaaagcttt ttttatagaa tgcagttctt ttggaacgga attgggcatc gttcttacaa
    30661 gtttaaagaa agtgtccgcc tctttgtcgt gaaacgcttg aagaatttct tgatagtaaa
    30721 aataggcgat tcgtaattcg tcagagatcg aaagcagacg atccaccact tcactttcgg
    30781 tgagatacgc ccaaccaaaa ttgcgccatt tggtccattt gtcataaaca agcttgtcct
    30841 gtcgtttgat cagaagccga gacaacgcct ttaattgtcg ataatatttg gcttgtgttg
    30901 gatcgtttcg atcaaagctt ttcatgattc gtacgcgaat atcctcaaat ttacgaatga
    30961 gatgtttgac aatgtgaaaa cgatccacaa cgagttttgc ctttggaaaa cattccttta
    31021 tcagagaggc ataagaaaca ttcatgtccg tcacgatgac ctttaccttc aatcgtgcgc
    31081 gtcgttcaaa ttgcataaaa taagaaacga gagccttttt cttccgtgaa ggaagaatat
    31141 ccagtaattt tccagtatcg ccatccatac aagaaaagga gtagggaccg acttgatttt
    31201 tcagtgaacg aaattcatcc attaataaac aacgcggtaa ccaatttctt tttacttttg
    31261 tcatggggat cagagaagcg agtgtccgag aaacggtcga ccaagaaacg ccgcaatgct
    31321 tagcaattgt cgtcattgct tgtttttcag ttagctcttc taaaatttta tagcgcactt
    31381 gtttagcgat aaagcagttt ctatcgacaa tgtaggtatt cgccgtaaaa taggtgtggc
    31441 agccacgaca gtggtagcgt tgtttcgcta aagcaagata agtcagttgg ttcgcacatt
    31501 tattaagttg aatgagcgat tttttctttc cgttcttaac gatcatgcct tcatgattca
    31561 tctgtttaca caaaggacag cgacgaattt ctttacttaa cgtcgcagaa acaacaagac
    31621 tcttgatatt cttaatgctc ttcgattcca catttgtgat gaaaatgttt ttatctttga
    31681 ttccaagtag tagtttgata tgatgaagat caggcataca gaacgctcct ttgattgtgt
    31741 tgtggtgatt caattctaac ggagcttctg tatgttttgt tttttcatgc tcaaaaggga
    31801 ccgatagaat gattttctat cagtcctaga aattatagag ccgattttga ccgacaggta
    31861 taaccctgcc ggtctttttt tgctgctaca ggaaaactac agactggcta cagggaaagt
    31921 acagatgcgc ttgccataat aacaatcgta ccagccacaa atcgtagttt tattgcaaag
    31981 gaggcattcg atcaaatgga aaaaagcaac tatcattcca atgcggatca tcacaaacgg
    32041 catatgaaac aatccgtgga aaagcgggct tttctatgtg cgttcattat ttcgttcaca
    32101 gtctgcacgc tgtttttggg gtggagactg gcttccgtat tggaggcaac acagataccg
    32161 cccatccctg caactcatac aggcagcagc actgacgtag tggagaattt ggaggaaaac
    32221 gctcttgcca ccgccaaaga acagggagat gaacaggaat ggagcctgat tttagtgaac
    32281 aggcagaacc ccatccccgc acagtacgat gtggagcttg agcaactatc aaatggtgag
    32341 cggatagata ttcggatttc tccctatctt caagatttgt ttgatgccgc aagaactgat
    32401 ggagtttacc cgattgtcgc atccggatac cgaacaacag aaaaacagca agaaattatg
    32461 gatgaaaaaa ttgccgaata taaggcgaaa ggctacacct ctgcacaggc taaagcggaa
    32521 gcagaaactt gggtggccgt gccgggaacg agcgagcatc agcttggtct tgctgtggat
    32581 atcaatgcgg acggaattca ttcaacaggc aacgaggttt atagatggct ggatgaaaac
    32641 agctatcgtt ttggttttat tcgtcgctac ccaccagaca agacagagat aaccggtgtg
    32701 agcaacgagc cgtggcatta ccgatatgtt ggcatcgaag ctgccacaga gatgtacaac
    32761 caaggggttt gccttgagga atatttaaaa ccagaaaaat gagaaaagga tgttatgtta
    32821 tggacagaaa aagattgaca cagcgtttcc cgttcctgct tccaatgaga cgggcgcaga
    32881 gaaaaatgtg cttttatgcg ggaatgagat ttgacggctg tcgctatgcg cagacgatag
    32941 gggaaaaatc gctttcccat ttgctctttg aaacggattg cgcattatac aaccacaata
    33001 ccggatttga catgatatac caggaaaaca aggtgttcaa cttaaagctg gcagcaaaga
    33061 ccttaaacgg cttattgata agaccggggg aaaccttttc tttctggttg ttcctgcata
    33121 cgccattgac aattatccag cgcagaggtc acgaagtaaa ggagtttcca gagccaaaca
    33181 gtgacgagat taaaggggtg gatgcaacca tttcagaggg ctggattgat ttaaaagtgc
    33241 gaaacgatac cgactgcacc taccaaatat gggtgacctt agatgatgag aaaatcatcg
    33301 gtcaggtgtt cgccgacaaa gagccccaag cattatacaa aattacaaat ggcagtatcc
    33361 agtatgtccg tgaaagtggc gggatttatg aatatgccca ggttaaacgg atgcaagttg
    33421 ccttaggtac cggggaaata atagattgca agctgcttta tacaaacaaa tgcaaaatct
    33481 gttatcccct cccggaaagt gtggatattc aggaggagaa ccaatgagaa aaagtgtggg
    33541 cattactgtt tttggatgcg aacaggatga ggcaaatgct ttccgcgctt tatcgccgga
    33601 ttttcatatt atccctacgc tgattagcga tgcgatatcg gcagacaacg caaaattggc
    33661 cgctggcaat caatgcgtta gcgtaagcca taagtccgag gtttccgagg cgacaattct
    33721 tgcgctgaga aaggtcgggg taaaatacat ttctacccgc agcatcggct gcgatcacat
    33781 tgatacgact gccgccgaga gaatgggaat ctcggttggc acggttgcgt attcgccgga
    33841 cagcgttgcg gattatgctt tgatgctgat gctgatggcc atacggggtg caaaacccac
    33901 catgcacgcc gtggcgcaac aagatttcag attggatcgt atccggggga aagaactggg
    33961 ggatatgact gtgggagtta ttggaaccgg ccatatcggg caagcggtcg tcaaaaggct
    34021 gcggggattt ggatgccatg tgctggccta tgataacagc cgaaaaatgg atgcagatta
    34081 tgtccagctt gatgagcttc taaaaaacag cgatattgtt acgctccatg tgccgctttg
    34141 tgcggatacc cgccatctga tcggtcagaa gcaaattgga gagatgaagc aaggcgcatt
    34201 tttaatcaac accgggcgcg gagcgcttgt cgataccggg gcgctggtgg aggcgttgga
    34261 aagcggaaag ctgggtggtg cggcactgga tgtgttggag ggcgaggatc agtttgttta
    34321 taccgattgc tcgcagaaag tgcttgacca tccctttttg tcgcagcttt taaggatgcc
    34381 gaatgtgatc atcacacccc atacggcgta ctacactgag cgtgtgctgc aggatactac
    34441 agaaaaaaca atcaggaatt gtctcaattt tgaaaggagt ttacagcatg aatagaataa
    34501 aagtcgcaat catcttcggc ggttgctcgg aggaacatga tgtgtcggta aaagccgcaa
    34561 tagaaattgc tgcgaacatt gatacggaaa aattcgatcc gcactacatc ggaattacaa
    34621 aaaacggtgt atggaagcta tgcaagaagc catgtacgga atgggaagcc gacagtctcc
    34681 ccgccatact ctccccggat aggaaaacgc atgggctgct tgtcatgaaa gaaagcgaat
    34741 acgaaacacg gcgtattgat gtggctttcc cggttttgca tggcaaatgc ggggaggatg
    34801 gtgcgataca ggggctgttt gtattgtctg gtatccccta tgtgggctgt gatattcaaa
    34861 gctccgcagc ttgcatggac aaatcactgg cctacattct tacaaaaaat gcgggcatcg
    34921 ccgttcccga atttcaaatg attgataaag gtgacaagcc ggaggcgggt gcgcttacct
    34981 accctgtctt tgtgaagccg gcacggtcag gttcgtcctt tggcgtaacc aaagtaaacg
    35041 gtacggaaga acttaacgct gcgatagaag cggcaggaca atatgatgga aaaatcttaa
    35101 ttgagcaagc gatttcgggc tgtgaggtcg ggtgtgcggt catggggaac gaggatgatt
    35161 tgattgtcgg cgaagtggat caaatccggc tgagccacgg tatcttccgc atccatcagg
    35221 aaaacgagcc ggaaaaaggc tcagaaaatg cgatgattac agttcccgca gacattccgg
    35281 tcgaggaacg aaatcgggtg caggaaacgg caaagaaagt atatcgggtg cttggatgca
    35341 gagggcttgc ccgtgttgat ctttttttgc aggaggatgg cggcatcgtt ctaaatgagg
    35401 tcaataccct gcccggtttt acatcgtaca gccgctaccc acgtatgatg gccgccgcag
    35461 gaatcacgct tcctgcactg attgacagcc tgattacatt ggcgttaaag aggtgataag
    35521 tatggaaaat ggttttttgt ttttagatga aatgttgcat ggcgtccgtt gggatgccaa
    35581 gtacgccaca tgggataact tcacaggaaa accggtggat gggtatgagg tgaatcgcat
    35641 catcggcaca aaggccgtgg cgtttgctct gcgcgaggca caaatccatg cggctgcgct
    35701 tggctatggc ttgcttttat gggatggata tcggccaaga actgcggtgg actgcttcct
    35761 gcgttgggca gcgcaaccgg aggacaatct cacaaaagaa aaattttacc ccaatataga
    35821 gcgagccgag ttgattacaa agggttatgt ggcctcacaa tccagccata gccgtggaag
    35881 cgcaattgat cttacgctct accacctgga tacaggggaa cttgtttcaa tgggaagtaa
    35941 cttcgatttt atggacgaac ggtcgcatca tacagcaaaa gggatagggg atgcagaggc
    36001 acaaaatcga agatgcttgc gtaaaatcat ggaaagcagc ggatttcagt cttatcgctt
    36061 tgaatggtgg cactataagt tgattgatga gccatacccc gatacctatt ttaattttgc
    36121 cgtttcataa tgaaagtatt ggttttgtat cagattttgg atttgataaa atctatgctg
    36181 gtcatggaca atcttttact ggaaagtggt taaagcatct tttgtaatac attgcaaatt
    36241 atagtattca atctgcccag cggcagaaaa gaaaaaaacc gctgttgggc agacctttcc
    36301 cacgcccatt ttgtattttg ctggcggcgg ttttgagaaa tcaaggccgc cgttcttttc
    36361 tggcagcaaa aggtgtggcg gcccatagga ggatgccgct atgctgtttt gctattgcca
    36421 tgctctaatc cacttccacc actcaaaaaa agccttgccc ctc
//
LOCUS       DAFLVO010000022        35882 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.022, whole genome shotgun sequence.
ACCESSION   DAFLVO010000022 DAFLVO010000000
VERSION     DAFLVO010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35882
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.022"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..1152
                     /locus_tag="L1U99_001149"
     CDS             <1..1152
                     /locus_tag="L1U99_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HBN1211702.1"
                     /translation="PSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSA
                     EAPKEKVETSGSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKED
                     IENFLAGGPSSAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPT
                     RKAIAKAMVNSKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALT
                     ATVKKYPVLNASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEI
                     NEKAKLAHDGKLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIV
                     NAEGEIVVGRVMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            1160..2566
                     /gene="lpdA"
                     /locus_tag="L1U99_001150"
     CDS             1160..2566
                     /gene="lpdA"
                     /locus_tag="L1U99_001150"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBN1211703.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            2728..3003
                     /locus_tag="L1U99_001151"
     CDS             2728..3003
                     /locus_tag="L1U99_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HBN1211704.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            3009..3776
                     /locus_tag="L1U99_001152"
     CDS             3009..3776
                     /locus_tag="L1U99_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HBN1211705.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            3944..5773
                     /gene="typA"
                     /locus_tag="L1U99_001153"
     CDS             3944..5773
                     /gene="typA"
                     /locus_tag="L1U99_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBN1211706.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            6034..7806
                     /gene="recQ"
                     /locus_tag="L1U99_001154"
     CDS             6034..7806
                     /gene="recQ"
                     /locus_tag="L1U99_001154"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBN1211707.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            7920..8222
                     /locus_tag="L1U99_001155"
     CDS             7920..8222
                     /locus_tag="L1U99_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HBN1211708.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            8225..9388
                     /locus_tag="L1U99_001156"
     CDS             8225..9388
                     /locus_tag="L1U99_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBN1211709.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            9414..12842
                     /locus_tag="L1U99_001157"
     CDS             9414..12842
                     /locus_tag="L1U99_001157"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBN1211710.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            12863..13987
                     /locus_tag="L1U99_001158"
     CDS             12863..13987
                     /locus_tag="L1U99_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211711.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            13977..14414
                     /locus_tag="L1U99_001159"
     CDS             13977..14414
                     /locus_tag="L1U99_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBN1211712.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            14398..14736
                     /locus_tag="L1U99_001160"
     CDS             14398..14736
                     /locus_tag="L1U99_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HBN1211713.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            14855..15415
                     /gene="rsmD"
                     /locus_tag="L1U99_001161"
     CDS             14855..15415
                     /gene="rsmD"
                     /locus_tag="L1U99_001161"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBN1211714.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            15412..15903
                     /gene="coaD"
                     /locus_tag="L1U99_001162"
     CDS             15412..15903
                     /gene="coaD"
                     /locus_tag="L1U99_001162"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBN1211715.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            15893..16936
                     /locus_tag="L1U99_001163"
     CDS             15893..16936
                     /locus_tag="L1U99_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HBN1211716.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            17095..17823
                     /locus_tag="L1U99_001164"
     CDS             17095..17823
                     /locus_tag="L1U99_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBN1211717.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            17939..18184
                     /locus_tag="L1U99_001165"
     CDS             17939..18184
                     /locus_tag="L1U99_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBN1211718.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            18181..18399
                     /locus_tag="L1U99_001166"
     CDS             18181..18399
                     /locus_tag="L1U99_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBN1211719.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            18535..19074
                     /locus_tag="L1U99_001167"
     CDS             18535..19074
                     /locus_tag="L1U99_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HBN1211720.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            19067..21340
                     /locus_tag="L1U99_001168"
     CDS             19067..21340
                     /locus_tag="L1U99_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HBN1211721.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            21378..22424
                     /gene="holA"
                     /locus_tag="L1U99_001169"
     CDS             21378..22424
                     /gene="holA"
                     /locus_tag="L1U99_001169"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBN1211722.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(22513..22767)
                     /locus_tag="L1U99_001170"
     CDS             complement(22513..22767)
                     /locus_tag="L1U99_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBN1211723.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(23167..23436)
                     /locus_tag="L1U99_001171"
     CDS             complement(23167..23436)
                     /locus_tag="L1U99_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211724.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(23906..24361)
                     /locus_tag="L1U99_001172"
     CDS             complement(23906..24361)
                     /locus_tag="L1U99_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HBN1211725.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(24499..26427)
                     /locus_tag="L1U99_001173"
     CDS             complement(24499..26427)
                     /locus_tag="L1U99_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBN1211726.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(26624..27457)
                     /locus_tag="L1U99_001174"
     CDS             complement(26624..27457)
                     /locus_tag="L1U99_001174"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBN1211727.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(27649..28353)
                     /locus_tag="L1U99_001175"
     CDS             complement(27649..28353)
                     /locus_tag="L1U99_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBN1211728.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(28376..29002)
                     /locus_tag="L1U99_001176"
     CDS             complement(28376..29002)
                     /locus_tag="L1U99_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBN1211729.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            29328..31703
                     /locus_tag="L1U99_001177"
     CDS             29328..31703
                     /locus_tag="L1U99_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HBN1211730.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(31727..32218)
                     /locus_tag="L1U99_001178"
     CDS             complement(31727..32218)
                     /locus_tag="L1U99_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HBN1211731.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            32405..33325
                     /locus_tag="L1U99_001179"
     CDS             32405..33325
                     /locus_tag="L1U99_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1211732.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            33479..33823
                     /locus_tag="L1U99_001180"
     CDS             33479..33823
                     /locus_tag="L1U99_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HBN1211733.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(34013..34513)
                     /locus_tag="L1U99_001181"
     CDS             complement(34013..34513)
                     /locus_tag="L1U99_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1211734.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            35041..35124
                     /locus_tag="L1U99_001182"
     tRNA            35041..35124
                     /locus_tag="L1U99_001182"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35075..35077,aa:Leu,seq:cag)
     gene            complement(35448..>35882)
                     /locus_tag="L1U99_001183"
     CDS             complement(35448..>35882)
                     /locus_tag="L1U99_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HBN1211735.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        11868 a         6262 c         7405 g        10347 t
ORIGIN      
        1 ccgtcacctg tcacagggac agttaaaaac gtgattgttc cagaaggcac tgtagcaaat
       61 gttggggatg tattagtaga aatcgatgct cctggacaca atagtgcacc gtcaactagt
      121 gcgccatcag ctgaagcacc aaaagaaaaa gtggaaacat caggttcagc aagtgtcgtt
      181 gaagctgccg atccaaataa acgtgtattg gctatgccat ctgttcgtca atttgcccgt
      241 gaaaaagatg tagatatctc acaagtaact gcaactggaa aaggtggcag agtaacaaaa
      301 gaggacatcg aaaacttctt ggcaggtggt ccaagcagtg caccagcgaa atcagaagcg
      361 ccagaagcgg cagcaccgaa agaagcagct cctgcagcag aaagcaaacc agctgcacca
      421 gcaaaaccat tcaagtccaa cttaggagac ttggaagaac gtgtagcaat gacgccaaca
      481 cgtaaagcta tcgctaaagc aatggtcaac agtaagcata cagctccaca cgtgacattg
      541 catgatgaag tagaagtgtc taaactatgg gataatcgga aacgatttaa agaagttgct
      601 gctgcaaatg gtacgaaact tactttcttg ccatatgtcg tgaaagcttt aacagcgact
      661 gttaagaaat acccagtatt gaatgcatct atcgacgatg caaaccaaga aatcgtttat
      721 aaacattact acaatatcgg tattgcaact gatacggatc acggactata tgtaccaaat
      781 gtgaaagatg cagaccgcaa aggaatgttt gctattgcag acgaaatcaa tgagaaagca
      841 aaattagctc atgacggcaa actatctgca gaagatatgc gcaatggaac aattacgatc
      901 agcaatatcg gatctgtagg tggcggttgg tttacaccag tcatcaacta tccagaagta
      961 gctattttag gtgtaggaac gattgcacaa caaccaatcg taaatgctga aggcgaaatc
     1021 gttgtcggtc gtgtgatgaa actgtcatta agtttcgatc accgtatcgt agatggagca
     1081 actgcgcaac aagcaatgaa taatatcaaa cgtcttttag ctgatccaga gctattaatg
     1141 atggaaggat gataaacaaa tggtagttgg agattttgct gtagaattag atacagttgt
     1201 aattggtgcg ggacctggtg gctatgtagc tgccatccgc gctgctgaaa tgggacaaaa
     1261 agtagcaatc attgaaagag agtatattgg cggtgtttgt ttgaatgtcg gctgtattcc
     1321 ttcaaaagca ctgatagctg caggacacca ttatcaagag tcactagatt ctgaaatgtt
     1381 tggagtaact agtgaaaacg tcaaactaga ttttgcaaaa acacaagaat ggaaagaaaa
     1441 caaagttgtc catacgttga cttctggtgt tggtttccta ttaaaaaaac ataaggttga
     1501 aacaatcgaa ggagaagcgt tcttcgtaga tgatcacaca ctacgcgtca ttcatccaga
     1561 ttcagctcaa acttattcgt tcaataacgc aatcatcgca acaggttccc gtccaatcga
     1621 gattccagga tttaaattcg gaggacgtgt gttagattct actggcggat tagcattgaa
     1681 agaagtacct aagaaatttg tgatcatcgg tggcggtgtg attggtgccg aattgggcgg
     1741 agcgtacgca aacttaggag cagaagtaac gattcttgaa ggctcaccac aaattttacc
     1801 aacttacgaa aaagatctag taaaattagt agaagatgat ttcaagaaaa aaggcgtaac
     1861 agtcgtaacg aatgcaatgg cgaaagaagc agtcgataac ggtgacagcg tgacagtgaa
     1921 atatgcagtg gacgggaaag aagaatccgt tactgctgat tatgtgatgg tcactgtagg
     1981 tcgtcgtccg aatacagatg atatgggctt agaacaagcg ggtgtcgaag taggagaacg
     2041 aggattgatc acggtggata aacaaggacg tacgaacgta cctaacatct atgccatcgg
     2101 tgatatcgtt ccaggggcgg cattagcaca caaagccagt tatgaagcaa aaatcgctgc
     2161 tgaagcaatc tctggcaaaa aagtagctgt agattataaa gcaatgccgg cagtagcctt
     2221 cactgatcct gaattggctt ctgtaggtat gacgatcaaa gaagcaaaag atgctggtat
     2281 cgaagcaaaa gcatataaat tcccattttc agggaacggt cgggcattat cgcttggtaa
     2341 aacagaagga ttcatccgtc tagttacgac gatcgaagat aacgtgctta ttggcgcgca
     2401 aatcggtgga gtcggcgcaa gtgatatggt ctctgaatta gctttagcaa tcgaatcagg
     2461 aatgaatgct gaagatatcg ccttgacgat tcatcctcat ccatctcttg gcgaaatcgt
     2521 catggatgct tcggaattag cattaggttt accaatccat atttgatttg aataatacag
     2581 gcgaaacgca actgaaaaat cagttgcgtt ttgtttttta gaattatcaa taatattatt
     2641 atgtaaactt aaaaatatga caacttcttg gtttattacc acttcctatg ctacactgaa
     2701 gaggaatatg aaataggaga gttgaagatg caagaatatc agtatccact tgatttagat
     2761 tggacaacag acgaaatggt cattgtaatg aagatgtggg aagatctgga acgtgcgaat
     2821 gaaaaaggga taaacaatga agcttttttg aagacttatc agcagtttaa aactgttgtc
     2881 aaatccattg gtgaggaaaa acgattggga cgggaatttg aaaaagcttc cggttattct
     2941 ttatatcgta cagtgcagca agcaaaaaaa aatccaaaca aaactttgag aatgaacggg
     3001 tgagataaat ggaacagatg attgatcata tcaagtcctg gcttgaagaa gctggtgaga
     3061 aaatcaaatc ttctcaacaa acattaacaa tctcgcaaaa atcaaatcga acggatctag
     3121 taacaaatgt cgatcgaaac atccagaatt ttctaatcga aaaaatccat tcctttgatc
     3181 cagaggcgaa aatattggca gaagaagaag ggtgtaatca attatcggat ctcgatggaa
     3241 gagtctttat catcgatcct attgatggca ccttgaattt tgtgattgaa ggggaaaatt
     3301 tttgtattat gctcgctgtt tatgaatccg gcgttggaaa gcttggtttc atttatgacg
     3361 tgatgagaaa tgaacttttt tggggtggaa aaggaatagg cgtgtataaa aatgatgagc
     3421 cattgcctag accagcaaat aaatccttat cggaaggctt acttggtgtg aatagttatc
     3481 ttttcggtca taataaatat ggaatccgag aaattgcgga aagcagcatg gggacacgta
     3541 tgtacggatg cgctggtctt gaactagtgg caatcttgaa aggaaaccac attgcttata
     3601 tttcaaacct tagcccttgg gattatgcag cgggaaatgt cttattggaa gagtttggta
     3661 tggtaacaag cggtcttttt ggtactcctt tgacatttga aaaaagggaa tactatttag
     3721 cagggacttc ttgtgcatat gcagaaatcg cagacctttt gaaaaaagaa ggctgaaaaa
     3781 aaggtagaaa tcattcacaa aaatgataaa aacgagcaaa agattaattt tctcgaaaaa
     3841 atgaaaacat tttactatat ttcatgaaaa aagtctgcta taattagcag tcgagtaaaa
     3901 tttgccctgt cataaagaac caataaaaaa ggagttagtt acattgaatt atagaaacga
     3961 tatccgtaac gtcgcaatta ttgcccacgt tgaccacgga aaaacaacat tagttgatga
     4021 actattaaaa caatcagata cattagacgc acatacgcaa ttgcaagaac gtgcgatgga
     4081 ctcaaatgcg ctagaaaaag aacgtggtat cacgatttta gccaaaaaca cagctgtaga
     4141 ctataaaggt attcgcgtaa acatcatgga tactccagga cacgcggact tcggtggcga
     4201 agtagaacgg atcatgaaaa tggttgacgg cgttgtgttg gtcgtagatg cgtatgaagg
     4261 aacaatgcct caaacacgtt ttgtattgaa aaaagcactg gaacaacata tcacaccaat
     4321 cgttgtcgta aacaagattg acaaaccttc tgctcgtcct gagcatgtcg tagatgaagt
     4381 tcttgaacta ttcatcgaat taggagcaga tgatgatcag ttagactttc ctgtgattta
     4441 tgcatctgca ctaaatggta cgtcaagctt gtcagatgat ccagcagatc aagaaccaac
     4501 catggcacct atttttgata caattattga aaaaatccct gctcctgtcg ataacagcga
     4561 cgaaccatta caattccaag tttcattact tgactacaac gattatgtag gtcgtatcgg
     4621 aatcggacgt gtatttagag gaacaatcaa agtaggagac caagtagcat taattaaatt
     4681 agacggaaca gttaagaaat tccgtgtaac gaaattattt ggtttctttg gactaaaacg
     4741 tctagagatt caagaagcaa aagctggaga cttgattgct gtctcaggta tggaagatat
     4801 ctttgtcggt gaaacagtta ctcctgtgga tcatcaagat gcgttaccta tccttcacat
     4861 tgacgaacca acattgcaaa tgactttctt agttaataat tcaccatttg ccggtcgaga
     4921 aggtaaattc gtaaccgctc gtaagattga agaacgtttg atggcagaac ttcaaacaga
     4981 tgtatcctta cgagttgaac caacaaactc tccagatgca tggacagttt ctggtcgtgg
     5041 agaattgcat ttgtctatct tgattgaaaa catgcgccgt gagggatacg aattgcaagt
     5101 atctcgtcca gaagttattg aaaaagaaat cgacggtgta aaatgcgaac cgtttgaacg
     5161 cgtgcaaatc gatacaccag aagaatatat gggtagtgtt atcgagtcct tgagcttacg
     5221 taaaggtgaa atgcaagata tggtccatac aggaaacgga caaatccgtt tgacattctt
     5281 aacacctgcc cgcggtttga ttggttattc aactgaattc ctttcaatga cacgtggtta
     5341 cggaatcatg aaccatactt ttgaccaata tctgccaatg cttcctggtc aaattggcgg
     5401 acgtcaccaa ggggcgcttg tttcgatcga tacaggaaaa gcaacgactt attctatcat
     5461 gagtatcgaa gaacgcggta cagtcttcgt agaaccaggt acagaagtat atgaaggaat
     5521 gattatcggg gaaaacagcc gtgataatga tttgactgtc aacatcacga aagcaaaaca
     5581 aatgacaaac gtacggtctg ctactaaaga ccaaacatct gtcatcaaaa aaccaaaaca
     5641 attgacgttg gaagaatctt tggaattctt gaatgatgat gaatattgcg aagtaacacc
     5701 agaaagcatt cgcttgagaa aacaaatttt agagaaaaat gctcgtgaaa aagcatctaa
     5761 aaagaaaaaa taatctgtaa aaggatgaag agagaaacca gcttgttata aaaaatagct
     5821 ggtttctttt tttgtccaac tcttttctgt ggagaagtca tctttgtcaa tggacataaa
     5881 ttcagaaaat acgccgaaag acgtttaaaa gacttttaaa aaacttattt ctagagagtt
     5941 tttgtttcat aataagataa tgtttcacga aaggagatca acttgtcctt cgaagaaaat
     6001 cgaagtaaaa tggcaagaga aaggagcggg aagatgaacg acttattaaa acaatacttt
     6061 ggctatgatg agtttagacc tggtcaaaaa gaaattatcc agaaagtcat tgatcaggaa
     6121 aatgtattag gaatcatgcc taccggaagt gggaaatcaa tctgttacca gcttccagct
     6181 ttactattag atgggcttac tgtggttgtg tcccctttaa tctctttgat gaaggatcag
     6241 gtggacgcgg cgaatcaatt aggtataccc gccactttta tcaatagctc gttagatggt
     6301 tacgaaacag ctagacgctt ccaagaaatc gatagacagc agtaccgttt actttatatc
     6361 gctcctgaac gttttatcat gccggatttt atccaagcaa tgaagcgatg gaacgtccgt
     6421 atgatcgcta ttgacgaggc acattgtatc tctcagtggg ggcatgattt ccgcccaagt
     6481 tatttacaga tggcgaacca gctagatcaa ctgccaaatc gtcctgtaat tgttgctttg
     6541 acagctacag cgactgtgca agtagctgct gacataaaaa gacttttaaa aattccagaa
     6601 aacaaccata ttcagactgg ttttgaacga gaaaatctac gatttcaagt aattaaagat
     6661 caaaaaaaag aacaatatct aatcgaatat ttaaagatca acaaaaatca atctggtatc
     6721 atttatgcag caacgagaaa agaagtagac cgtctctatc atttgcttaa aaaattcgat
     6781 ttttccgtgg gtagatatca tggtggtcta aatgagaatg agcgaacaga aatgcaagaa
     6841 gcctttttat acgatcgctt gcagctgatt gtagcgacaa atgcatttgg tatgggtata
     6901 aataaaagca atgtccgttt tgttatccat tatcaaattc ctggctctct agaagcatac
     6961 tatcaggaag ctggtcgggc gggaagagat ggtctttcca gtgaagccat cctgcttttc
     7021 tctcctcaag atatccaagt ccaaaagttt tttatccagc agtcccaaag agaagaaggg
     7081 caaaagcaaa aagaatatga aaaattaaaa gcgatgacag aatacgtgta tattgagtcc
     7141 tgtcttcagc aatacatcct aaactatttt ggcgagacaa gcagtccgtg caaccgttgt
     7201 ggtaactgtt tagatgacag agaaatagta gaagtaacga cagaagcaca gatggttctt
     7261 tcttgcttaa aacgtatggg tgagaactat ggtaaacaaa tgctgatgaa agtcttagca
     7321 ggatcgaaag aacaaaagct gcaagcttta ggttttggac atttatctac ctatggactg
     7381 atgaaaaacc aatcgcaaaa agaaacgatg cagttaattg aatatttgat atcgaatggc
     7441 tatcttctga ccatcaatgg tgagtatcct gttttgaaag taacagaaag agggatacaa
     7501 gtattgaaag gacaagaatc tgtttatcga aaggaaccca agaaagtcca gcagctatcg
     7561 gatgaagaaa ccgatacact atttgaagtg ctgcgggaac tgcgaacgga tctagcatca
     7621 gaagcaggcg ttcccccgta tgtcgtattt tcagattcca cattgaaaga aatgagccga
     7681 atacgtccat caagcagatt ggagatgctt cagataaaag gagttggcca aagcaagctt
     7741 gataaatatg gcgaagcctt tttatctcgg ataaaaaatg cggactctaa cgttctggat
     7801 aagtagaaag aacgaatacg taaaaatgaa taaaaacaac tggttaaatc tgtttttttt
     7861 gctccttatg aaaatcaaat atgttataat taaggaatta gaatgggagg taagcacaga
     7921 tggattcttt gtcgaaaaaa cttgcgatcc aagtattaaa tgatgaagca gaacggatca
     7981 aacgattaat ccgaaatcaa aacaacagtc tctgtatctc acaatgcaaa gccttcgaag
     8041 aagtggtaga tacacagatg tacggctttt cccggcaagt cggttttgct gtccgtatag
     8101 gagtaatcgg aaagaacgag ggccagctga tgttaagtga gctagaacga gaattgaatc
     8161 agttatatag tgaggtttac caagaaattt atgataaaaa agaagttggc aaggaggaat
     8221 agacttgcct aagaaagtga aaaaaaggca tctattagac tatagcatct tgattcccta
     8281 tttaatttta tgtgtattgg gattgatcat ggtatatagt tctacgtcgt atctattatt
     8341 agaaaacgga caaaatccgt ccgcatcagt cattaaccag agtatttttt gggtgcttag
     8401 cttgattgct atcgcactac tttataaaat gaaaacagat gttttgaaaa accagcgttt
     8461 gatcatggca gccatcgcag ttttgacgat tttgctgctg attgttgtgt tttttggtaa
     8521 ggagatcaat ggggcgaaag gttggctgca aattgcagga ttctcgatcc aacctgccga
     8581 atacctaaaa atcatttcta tctggtacct gtctctgact ttatctaaaa gacaaaacag
     8641 tgtacaaaaa gattttcttg ggactgtgaa acgtccactt gcaatggtta tcggacttac
     8701 tgcattagtc gctattcttc ccgattttgg taatgcggca gttatctttt tgattatttt
     8761 ggttctgctt ttagccagcg gagtcaatta tgtgtatact ttgattgtag gagtaggagg
     8821 cttttgtcta agtactttta cgatctggct gatcaatatc acaaacggaa agatcttacc
     8881 cggacgttta cagtatatct ataatcgatt tgctatttac caaaatcctt tctcagacga
     8941 attaaataaa gggcatcaac tagtcaacgg ctactatgcc atgttcaacg gaggactatt
     9001 tggcagggga ttaggtaaca gtatccagaa aaaaggattt ttacaagaag cacaaaccga
     9061 ttttatttat gcaatcgtag tggaagaact gggagtgatt atggggattt tgatattagc
     9121 gttgctattc tttatgattg tgcgcattgt ccttgtaggt atccgttcaa aagatccgtt
     9181 caattcgctt ttgtgcattg ggatcggcgc aatgtttttg atccaagtat ttgtcaatct
     9241 tggaggaatt actggcgtta ttcctttgac agggatcacg ttcccatttt taagtcaagg
     9301 aggctccagt ttgctgatgc tttcgatttg tgtcggcttt gtcctcaaca tcagtgcgga
     9361 tgaaaaacgc aagagcttag gtttataata aaaaaagatg taggagtggt tcgatgaaaa
     9421 aagttttagt tgctaacagg ggtgaaatcg ctgtacgtgt atttcgtgct tgtacagaat
     9481 taggaattaa aactgttgga atctatgcag aagaagatga atattccgta caccgtttca
     9541 aagcggatga agcatattta gtaggacaag gaaaaaaacc gattgatgcg tatctagata
     9601 ttgaagggat catttctatc gcgaaagaat gcggagctga cgctattcat ccgggttacg
     9661 gtcttttgtc ggaaaacttg aattttgcgc aacggtgcga agaagaaggc atcatttttg
     9721 ttggacccaa actgcatcat ttagatattt ttggagataa aatcaaagca aaagctgcag
     9781 ctatcgaagc ggggattgct tcgattccag gcacagatgg accaatcgct tctatagacg
     9841 atgccttgga gtttgcgaaa caatacggtt atccgattat gatcaaggca gctctaggcg
     9901 gcggcggacg cggcatgcgt gtagctcacg atgaaaagag tgcaagagag ggctacgaac
     9961 gtgcgaaaag cgaagcaaaa gcagcctttg gtagtgatga agtgtatgtt gaaaaataca
    10021 tcgctaatcc taagcatatc gaagtacaga ttctcgggga tacgcatgga aacgtcatcc
    10081 atctttttga aagagattgt tctgttcagc gccgtcacca aaaagtagta gaagtagcgc
    10141 cttgtgtctc tatgaatgaa cagcaacgtc aaaaaatctg ccaggcagct gtccaattga
    10201 tgaaatatgt cgggtatgtc aacgcaggta cagtagaatt tcttgttgaa ggagatgatt
    10261 tttactttat cgaagtcaac cctcgcgtcc aagtggaaca tacgatcaca gaaatgatta
    10321 cagatattga tatcgtaaca acgcaactgt tgattgctca aggtttggat ctgcataaag
    10381 aaatcggatt gcctcagcaa gaaggaatta aattaaatgg ttcagccatt caatgccgaa
    10441 tcactacaga agacccgttg aataactttt taccagacac agggaaaatc gatacgtatc
    10501 gttcacctgg tggttttggc gtacgtctgg atgtcggaaa tgcttacgcg ggctatgtag
    10561 tgacaccgta ttttgattca ttgctagtaa aagtatgtac gcatggtgct acctttgaaa
    10621 cagccattca gaaaatggaa cgttgcttga aagaatttag aatccgtgga gtgaaaacaa
    10681 acattccatt tatgctcaat gtcatcacac atcctgaatt ccaatcagga aatgcaaaaa
    10741 caaccttcat tgatagtaca gcaacattat ttgaatttcc tcgactacga gaccgcggaa
    10801 acaaaacgat gaaatatatc ggtgaaatta ctgtgaatgg ttttccaggt atcgaaagtg
    10861 gcgaaaaacc attttatgaa gaaccacgta tgcctaaaga tctaatcaca agaactgatt
    10921 acgtaacggc taagaatgta ttagatgcga agggtgccga tgctttggtc gaatggatca
    10981 aaggacagga aaatttgttg ttgacggata cgacatttag agacgcccat caaagtctgc
    11041 tagcaactcg tgttcggaca aaggatttca agcagattgc acgtttgact ggagaaggtc
    11101 ttcctgaact cttttcaagt gagatgtggg ggggagcaac atttgatgtg gcttaccgct
    11161 ttttgaatga agatccttgg caacggttga gaaaaattcg ttctttaatg cctaatacgt
    11221 tgctgcaaat gcttttcaga ggttcaaatg ccgttgggta ttctaattat cctgacaatg
    11281 tattggtgga atttgtcaaa gaagcagcag cgcaaggaat cgatgtattt cgaatctttg
    11341 atagtttgaa ctggactcca caaatggaaa aaagtatcca agctgtacgg gatactggta
    11401 aaatcgcaga ggcagctatt tgctatactg gcgatatcaa cgatccaagt cgggcaaaat
    11461 acaatgttca gtattataaa gacatggcaa aggaactaga acaactgggt gcgcatatca
    11521 ttgcaatcaa agatatggct gggctgctta aaccgcaggc agcttatcgt ttgattagtg
    11581 aattgaaaga aacgacagat ctgccaatcc atctgcatac tcatgatacc agcgggaatg
    11641 gaatcatcac ttattctgct gcttcaaaag caggagtaga catcgttgac gtggcaatga
    11701 gtgcaatgag tgggaatact agtcagccta gcatgagcag cttgtattat gcactggtca
    11761 atggtccacg gctgccagaa atcacgattg aaaatgcaca gaaattaaac cattattggg
    11821 aagatgtgcg catgtattac aaaccgtttg aaaacggctt gaatgctcct gaaacagaag
    11881 tatatatgca tgaaatgcca ggaggacagt attcgaatct acagcaacag gcaaaagctg
    11941 tcggattagg tcatcgctgg gatgaaatca aacaaatgta tcatactgtc aacttgatgt
    12001 ttggcgatat cgttaaagta actccatcat ctaaagtagt tggagatatg gcactattta
    12061 tggtccaaaa tgatcttaca gaagaagata tttatgaaaa aggcgaaaca ctaagtttcc
    12121 ctgaatctgt tgtgactttc ttccaaggag aactagggca acccgttggc ggatttccta
    12181 aaaaattgca aaagattatt cttaaaggca gacctgcatt gaatgaacgt ccaggtcttt
    12241 tggctgaatc agtcgacttc aacgaagtaa aaaaagaatt ggcagaaaaa attggctatg
    12301 aaccaaaaca agacgaagta ttaagctatt tgatgtatcc gcaagtcttt ttggactatc
    12361 aaaaagcata taatcaattt ggcgatgtta cattactgga cacaccaaca tttttccaag
    12421 gtatacgttt gggtgaaaca atcaatgtac aaatcgaacg cggaaaaacg cttatcattc
    12481 gtttagatga aatcggagaa cccgatatcg aagggaatcg cgtactgttc ttcaatttga
    12541 atggacaaag acgtgaaatc actatcaaag ataattcgat catcagtacg gtccaaaccc
    12601 gattgaaagc tgaaccgaca aaccgagaac aaattggagc aacgatgtct ggttctgttt
    12661 tggatgtatt agtgaaaaaa ggcgataacg ttaaaaaagg tgatacgttg atgattactg
    12721 aagcgatgaa aatggaaacg gccatcgaag cacgttttga cggagaagtc gcacatgtat
    12781 atgtgtcttc aggagacact atttcgtctg gtgacctttt gattgaagtg actgagaaat
    12841 aataagcgaa aggtggggaa acatgaaaag actgggtttg ttttggctga ttctgctatt
    12901 agttattgtg gcattctaca tggaaccagt cttgtttccg ccaaaacttg aagtgaagga
    12961 aaactctgat caacaaatat caaaccaaat gacaacgtgg aaataccagg agcttaaagc
    13021 aactggtttt tctacttata tcggaaaacc gatcgatcag ctggaaaagg attttggcca
    13081 agcctatgat cgattaacta gcggatttgg ttttgaaaca agatattatg aaaataaagc
    13141 tagtcatctc acatttgaag cgaacatcca agacagcaga gtcacaactg ttaaagtact
    13201 gcaaacaggg cctgctgata tcgcgccgtt ttatttaggg atgacgatgc aagatcttac
    13261 gaaaatcact actatctata ctaatttcac ttttgagtac catgatacag aagttggaat
    13321 cgaactaatg gaagaggata tgaattatcg tccgctaatt gcttttgata acgacacttt
    13381 tgctatttta ttttttgatc aaacaacaaa cggcctattt tcagttgtgt atttagataa
    13441 agatagtctt ttgaaactat tgccatatca agtgtttggt gaaggccttc cacattatca
    13501 agcagataaa tcggctgatt gggaatcaat caatcgcgtt aaagaacgaa aaagtacgac
    13561 tttattaaat atgcttagaa gagaagacga acttcccata tacaatcaaa cacttgcctt
    13621 tcaaaaccac agtcagctgc tactacatga ttttttgaca aggcctgagg aaatattgtc
    13681 agaggaacgt atggctgatt ggcaaaaatc gctaggcagt gctcaaacga cagtgaaatt
    13741 ctcactgacg aatgatgaat tggagaagtt aatcagtaaa caaaaattag aaaatactag
    13801 tgggctattt attcatccgg cgattgacgc tactttttcg tttttatatt ggtacagcga
    13861 tccttacaac catgaccgtt tcatggaccc gggaacggat tctgtaggca ttgctttttc
    13921 taaagaaaat atgttagtct tattgcaaga agaaaacgga gaaagtagtg atagcagtga
    13981 tcgttaacga agagctgttt caactggagg atcaatgcct ccaagtcgct gaaatgataa
    14041 aaaagagtaa aacgatggct tcttatcttg aacataaaca gtcaatggaa gaatctgcaa
    14101 aagtttgcca gttgaaagaa gcgttcttgt ctaagaaaga agcatttgaa aatgtagcgg
    14161 catatggtga gtatgcacct gattatcgtg aaaaaaaacg agctgttcga aaagcaaaaa
    14221 gacagcttga tatggatgag catgttgcag ctttccgata tagtgaaaca cagctgcaaa
    14281 gtctgttgga tcaaattgtc caagtacttg ccgaagaagt ttctaatgaa atcaaagtag
    14341 atgcaggtag cccgtttttt gaaacgaaaa aacactttgg atgcggaggt aattgtcatg
    14401 caattagaca atagtgaatt tgaaataaca aaacgacgcg ggctgatcgt atgggtctac
    14461 agcttaaaac aattaaagaa tctgaaaaag ttcggcttgt tgcattatgt ctcaagaaga
    14521 atgaaatatg tcgtgcttta cttaaatgaa gagacattgg aagaaacaga agaacgaatc
    14581 cgtaaattac attttgttcg aaacgtagaa cgttcttacc gaccggatat cgaaatgaat
    14641 tttgccgaaa aaataggaaa caaaacagta ttaaaagacg aaggtttcga aattgaagag
    14701 ctaaatacag aaatccgatt agctgaacat ctttaaaaat ctcttatgag cagtttttaa
    14761 ataaaaaata acttggataa cgatcgattt ttgatcattg tccaagtatt tttttggtat
    14821 actagtacca gtaccatttc taaggagtga gtagatgcgg ataatatcag gaaattatgg
    14881 cgggcgccgt ttaaaaagtt tagcaggggc gaacaccaga ccaactacag ataaagtaaa
    14941 agaatccata ttcaatatga ttggaccata ttttgatgga gagacagtat tggatctgtt
    15001 tgcaggaagc ggtggtttag ctatcgaagc agtatctaga ggctgcagtc atgcggtatg
    15061 cgtagacaaa aattaccaag cgctaaaaat catcaaagaa aacatcgaaa ttacgaaaga
    15121 accagagaaa tttaccacaa taaaacttga tgcggacaaa gcaatcgaac ggctagcagc
    15181 ggagaaacaa caattcgact acttgtttct tgatccgcca tatgcaaaac aaaaaataat
    15241 cgatcaaatc cataaaatgg aagaactggg acttttttct aaaaccgcag ttatcgtatg
    15301 cgaaacggat aaaacagtcg aattgccaga aactgtggct ggattccatc aaataagaaa
    15361 acagatttat ggcataacgg ccgtaactat ctatagaaaa gagggaaatc aatgaaacgt
    15421 gcattattcc caggaagttt tgatcctttt acaaaaggtc acttagatac ggtggaacgt
    15481 gcggctaaat tattcgatga ggtagtaatt ggtgttttta tcaatacttc aaagaaaagt
    15541 ttgtttcccc cagaagaaag aatgacattg atcacaaaag ctgtttctca tcttcctaat
    15601 gtaaaagtca tgcatcaaga aaatcaattg acggtagaaa cagcaaaaga gattggtgca
    15661 gatgcgttga tcagaggcat acgaagtatc aaagactttg aatatgaacg agagattgct
    15721 cagatgaatc atcatctata tgatgaattg gaaactgtct tcttattagc aaaaccagaa
    15781 tatagtcacg tgagttccag tattttaaaa gaagtactgc actttggcgg agatgtgagc
    15841 agctacttac cgccagtgat caacgaagct ttagctggaa agcgtgaatc aaatgaaagc
    15901 taaacaatgg ttgaaaacag tactgattat catatttgga atgttgatca ttggatttgt
    15961 agtagttccc ttgccgtatt atgtagaatc accgggagcc acgatcgatc tgaaagaact
    16021 aattacggtc aatgataagg aagataaagg ttctgggtct ttctctctta cctctgttgg
    16081 tatcaggcaa gctacaggtt tcttagcttt aaaagctaaa atgacccctt ttgaagaatt
    16141 gatcagtgaa gaagaattga ctggtggggc gacaaatgaa gaatataatc aaatgcaaca
    16201 gtattatatg gattcttccc aaaatgcagc aatcgaacaa gcgttaaaac ttgcagacaa
    16261 gccttataaa atggaattca aaggcgtata tgtcatgagt gtagagaaaa catcgaattt
    16321 ctttggcaag ctttcagttg gagatacagt aacaaaagta gacgggaaaa gctttcaaag
    16381 tacagaagca tttatggatt atgtaaaaag ccaaaaagtt ggacaaacaa tcgaaatcag
    16441 ttatttgcat aatggtgaag aaaaaacagc ttctggtgat ctgatcgagt taccaacaga
    16501 taaaaaggca ggaataggta tcacgcttac tgaccatacc gagatcgaat cagatacaga
    16561 tgttcgtatt aattctggct ctatcggtgg gccatcagcg ggattgatgt tcactttaga
    16621 aatctatgaa caagtcactg gtaaaaactt gcgacatggt aagcaaattg caggaactgg
    16681 aacgatcaac agtgaaggag aagttggccg aatcggagga atcgataaaa aagtggcaag
    16741 tgcggataaa gctggcgtag agattttctt tgcaccagat gatacgattt cagacgatgt
    16801 taagaaagaa tatcctgaaa taaaaaccaa ctacgaagaa gcaaaagctg ccgctaaaaa
    16861 attgaattcc tcaatgaaaa tcgtaccagt aaaaacagta caagaagcgc ttgactatct
    16921 agagaaaatg aaatgaaact aaataattaa agaggggttg tgacacgagt tctgtcacaa
    16981 cccctctttt tcgtcaaaaa tcttcacgat aaaaataaaa acaaaagaaa aaattgacgt
    17041 aattagatgt tgaagggacg attttgccag agctcactgt ttcttcaatt ttaaatgaaa
    17101 ggagtaatga atgattttta ctggtcattc tttgaaaaaa gaacaatgat agaaaaaatc
    17161 agcaagaaaa tactagcttc acccaaattg atcatttgga tgtctatgat agttcttatc
    17221 ttttgtatcg caagtggttt tttattatca aatttgctat tttatagaga aacagaagag
    17281 actgctgcaa aagaaatact ttcttcgttt agttccagtg gagaagatcc atcagctgaa
    17341 ggaaacgatg tagaagagga tgctcgtcca aaggtcatgt acaccgatat caaaggaagt
    17401 gtgaaggagc ctggtatcta ttccttttct tcagaagaac gggtctatga tgtactaaag
    17461 cgtgcaggtg gattattaga agaagcggat agcgatcgaa tcaacttttc tgcgaagata
    17521 gaagatcagc aagtcctata tatccctgct gtaggtgaag agctgccaga acatcttgat
    17581 cagttggcat cctcggaagg aaaacagcct acagcagatt ccgagcctcc caaaataaat
    17641 atcaatacag ccactccatc agaacttcag cagattcctg ggatcggatc agtcaaagcg
    17701 caagaaatca ttcgatttag agaagaaaac ggatccttcc agaaagtgga agacctgcag
    17761 gagatttctg gtatcggtga aaagacagtt gaaaaactaa aaaacttcgt tacaattaaa
    17821 tagaatgatt caaaatcgac tggcacgagc aataaatgga cgctaatgga tactaagaat
    17881 aatccaattc taagagcttg gcaggacgag gaggtagtat ttttggatag gaaatagctt
    17941 gattgttcgc aaagaaacat taaaaaaacc aatgctgaat gtctatctcc aaaataaaat
    18001 atctgggatt catattatga atacggctgt cagcggcaat aacagtcaag ctctacgaga
    18061 acgctttgcc aaagatgtac ttagctatac agcagataaa gtatttattc tcattgggac
    18121 gaatgatcta gcagagcata aacaactttc taaagaaacg taccaaaaaa tctgcagtgg
    18181 atgatagttc agctgaaaaa agactatagt tctgatcatg ctttctttat cacgccacca
    18241 gcagtcgatg agacaaaaca aaaatatcgg aataacaagt tgatcaaaga atatatctct
    18301 gttctcacag aagtagcaaa acgccatgat tgtgaagtat cgatttttat acggaatttc
    18361 ttgaacaaat ggattcgaag aatttttata atgggctaat ggatgacgga cttcatttcg
    18421 gcagtgaagg gtaggatctt ttgtcagaca ggatgattcg ttatatttaa agaatatttt
    18481 gtttaagcaa tgagtacttt ttaatcaact tgaaaaaacg gaggaatata aaacatgtta
    18541 gaaaaatctt caaaagcatg cgatacgaat aaagaaaaag ttactgataa gtcacataat
    18601 gaacgcattc cttgggacca gtactttatg gctcaggcag tactgttatc tttacgtagt
    18661 acgtgtacac gtttagaagt aggagcgaca ctcgttcgag aaaaaaggat cattgctggc
    18721 ggctataatg gagcagtcag tggagatgtc cactgcatag atgaagggtg ttacgtcgtg
    18781 gatggacact gcttgcgaac gatccatgca gagatgaatg cactcctaca gtgtgcaaaa
    18841 cttggtatcc cgacggaagg ttcagaaatc tatgtcacac attttccatg tttggcctgt
    18901 acaaaggctt tgttgcaagc tggtgtgaaa gggatcaatt atctccatga ctatcgaaat
    18961 gatccttatg cccaagcgtt gatcgaacaa ttaggtgtat ctgtacacca agttgcttta
    19021 gactcacagc atttttcaaa acttcaaaat gaattaacag gaaaacatgt ctagcgtttt
    19081 agaaaggcat gttcgaaatc ggttgatttt tccggcaatt acgtcgatga ttatctgttt
    19141 gttgtattac actgacaatt ggggttatcg tttgcttctt gccggaattt ttttatggtt
    19201 ttcgctaaaa gaaggacgtt ttatcgcgta cttgtgtatt ttgtgtagca taacggtatc
    19261 catttcttat aggctacaag agtattcatt tttagaggaa aaaacaacat ctgcgcaaat
    19321 tactgtattt acagatacga ttcgtgcaaa tggtaatttt ttgacaatgg aaggaaggtt
    19381 atcagagaat aaacaaaagc tccagctttc ttatcaagta aacacagaag cagaattgaa
    19441 aacatggctt aacttccgag gaaagggaat agaattgact gctgaaggcg agttcatctc
    19501 tccagcaaaa aagcggaatc tttataattt tgaccaagaa gcttacttca ggaaccatag
    19561 aatttctgga cggttccaaa ttcaaaagat tgaacagatc accatgcaaa atcactggcg
    19621 aaactggctt cagagaaaaa gaggatcttt tatctccttt gtccaatctg aatttccgca
    19681 aaaaacaagt gtatatatta attctttatt atggggctat aaagatgcag gattcagaga
    19741 accagaagaa atttttaggg agagtggttt gctgcatctg ttcagtctat cgggtctaca
    19801 catccaattt tatttagggt ggctgtatta tttgtttcga cgtatcggat ggccactaca
    19861 cgtcagtatt attccgttga gtctactaac tatctgttat gtttctattg caggaagttc
    19921 tatttctgtt ttgcgtgcta gtttgctgtt tttattgcga ttgctagtca aattgctgaa
    19981 taagcattat tccaccatgg acttatttgc agttgtcttt tggcttcttt tactatttga
    20041 tcctcgattt ctttttcatg cgggtggaca gcttagtttt ttcatgagtt ttttgtttat
    20101 cctgatttct tttgatggag attggttgaa aaaaacggcc tctcacgtcc tgtttactat
    20161 gatcacgatg ccgttgattg tatggcattt ttatgagtgg cctattttag gtagtctttt
    20221 tacattactg attgcaccgg tattcaagtt tctttttctt cctggtgtgt tatttctcac
    20281 actcttcaat cgctggctgc cggaaacttt acttttgctg atagaagagg gattaatctt
    20341 atttgagcga ataatcgatt tttcttcagg gtcgtctctc attataggac gtttgcccct
    20401 tgtgctatct gggatgtata ttttcggatt actgatttgt atggataggt tgaaagaaca
    20461 acctgtgaaa cacttgtttt atgttggtct tttttctttt atttttttga ctttgccatt
    20521 tttacgcttt tcttcaacga tcgcttttat cgatgtcggt caaggagaca gtatcttttt
    20581 gcaaagtcct tttcgaaaag aaacgatttt gatcgatact ggaggtcagt tacactttga
    20641 aagagaaaag tgggcgcaag gtatgatacg tcctcctgct gaaagaaata tcgttccata
    20701 tctaaaaggt caggggataa gtgtaatcga taaactcatc ttgacacacg acgatacgga
    20761 tcatgtggga gaattaccca cgttatctca gcattttact atcaaaaaaa tttatatcgg
    20821 ttggggcgct ggacgaaatg agccattaca aaggcattta tctgaagctc aaaaaaatgg
    20881 tactgagatc attgaaatca aacatgggga caggatcagc ggttattatg atctttatgt
    20941 attgactcct tttgaaaagg gagagggaag aaatgaagat tcgattggtc tatggatgga
    21001 atataacaat aggcgctttt tatttttagg agatttgaat caagcaatgg aaaaacaatt
    21061 gcttttgatt tatcctaatc tgaaagccga tgtagtcaaa ttaggtcatc acggtagccg
    21121 tacgtcaagt aacacagatt ttctttccca tattgaagca aaacatggga ttatatcctg
    21181 cggcgtaaat aatcgttatg gtcacccgca cagcgaagta ttggagacac tagaagaaaa
    21241 tcagataaaa acatggcgaa cggatcaaca aggaatgatc acctatcgct ggcatccagt
    21301 ttttcatcct catgggctag tggaaacaat gatagactag taattctcat ctgctcatgg
    21361 taggataatt tttgaaagtg gtgagtaatt tgagtataca agcagagtta caaaaaatac
    21421 gtaaagaaaa acttgcatct tgttacttga ttttaggaac agaaaagttt ctccaagatc
    21481 aagttcggac agaaattgtc aaaaaaatcc aattagaggg cgaagatgac ttaaattttt
    21541 taagttttga catggaaaat gcaagtttag atgaggtagt agctgaagca gagacgttgc
    21601 cgtttttcgg agatcaacgg ttagtattcg tagagaatcc ttatttttta acaggtgaaa
    21661 aagtaaacaa tggaatcgaa caaaatactg atttattgac ggcttatttg aaagaaccat
    21721 tagaatcgac tgtattagta ttctttgcgc catatgaaaa gttggatgaa cggaaaaaag
    21781 taacgaaaca attgaaaaaa acagcaatta tcatcaatgt ccaacagttg aatgaaaaag
    21841 aagtacgtca atatctgatg aataccttag agaattcctc aatcaaaatg gaacgaagtg
    21901 caattgattt attcttgagg ttgaccgact tagatttatc caaaatgatg agagagttac
    21961 agaaattggt cctttatgga caaaatcaac agcaaatcac ggtaagagaa gtagaagaat
    22021 tagttcctaa aacgttagaa cataatattt ttgacatgac ccaatatatt ttaaaaggga
    22081 agacggaaca agctttgcgt ttatacgaag atttagttat gcaaggggaa gaaacaatca
    22141 aaattaatgc gattttgctt tctcaattac gtttattttt acagacaaaa tttcttgtaa
    22201 agattggtta tcagcaggca aatattgctg aaacattgaa aatccatcca tatcgtgtaa
    22261 aacttgccat gcaggaagta aaaaaattcg atgaacattt gctggtacag ttgtttgatc
    22321 aattagttga gatggattat caaatcaaaa cgggacaaat cgaaaaagaa ttaagttttc
    22381 aactattcgt tttgcgcaca gggcagttgt taagaaatcg ataagaagaa agacgagggc
    22441 aaagcatgcg ggaaggtcgt ttgtttttgt cctttttttg acaaataaaa aaatcggccg
    22501 aagccgattc ttttatttag cgattttttt gcttaaacga gatttgtcgc ggttagcttt
    22561 gtttttgtgg attagacctt ttgattcagc catatcaata gctttaacag cttctttata
    22621 taacgcatct acgttgtcag cacctgaagc tacagcatct tcaaattttt tgattgcagt
    22681 acgcatagcg cttgtttgag atgaattttt cacattagcg ttttcgcttg tacgaacacg
    22741 tttgattgca gattcaatgt ttggcattag tttcacctcc gataacttaa gttcttacgc
    22801 gtgttaccgc ataattcaac attcattatt atacctaaag gcagcgtgct ttgcaatatg
    22861 aacatgacaa gtttttttcc ttaacagtct tttattagga ttttttttca gtaaaaacgg
    22921 atagtacaag ctgaaaaaaa tcaaaaagac gctattgtgg gaggcaatag cgtcaaacca
    22981 aactagattt ttatttatct atttaaacaa agtttgaatg ggaatgtttg gtactaagtt
    23041 attatataac aaagagaacc gtttgcaaag ttttttttga aaagggatac gattccctgt
    23101 tgttctttgt ttttctatta agaaactgca gttattttat aaccagtatc ctttgatcag
    23161 taaaggctat tctggtgtac cgattatttt aatgtattca tcgatatttt ttatcaacat
    23221 tttttttatg accaactggt tccgacggtt ccatttgcca cttacttcca gcacatattt
    23281 atttaggggc aaacgtaaga tatattttgc caaatagcga tctttaagca ggccattgat
    23341 cacacggtcc tcaagctgca agttgatccc agtcagcatc attggctgtt cttgtaaaac
    23401 gtacgtatca attaaaagac cttcaaaagt ttccacaagc gtcttccttt cttttcaaag
    23461 taacctgaaa acaggcacta attcttccat tttgatattc gttgaagtgg atgcgatcat
    23521 tctttctttt gtccactgta atctagtata acaaaaaaga gcagaagagc caaaaagaaa
    23581 aaagagcatc gaattctata ggaagtctca ttggcacggc ctaaattatt acaaaacatt
    23641 gattaaaaaa agcccctgca tcgcaggagc atcccctata tcgttttaat aggtcaatca
    23701 aaaagcagta tcaaacacat tttgtatcaa atcaggaaat aatagataag ctaagcccag
    23761 aatcaaaagt accgctagaa gaaaccagcc gattgttcct atgaaatact ttaatttttc
    23821 gaacattgta tcacctcgtt gtcagtatat cacggatcag taaattgggg gtgttaagaa
    23881 tctcctaaaa tagacaaaat ttgttctatt ttcctaaagc aaatacttgt aagatacagt
    23941 aagtgatacc agaagcaatg accggtccgg cggcgattcc tcttaagaag acaacaccta
    24001 aaatcgtgcc gaaaacaagt gcaacagtga tttgtggatc agaagcaatc aatcctacac
    24061 ccttggaaga taagacagcc actagcccac cgcaaaaaac agctacccag ccaatagggg
    24121 atttaaaggc ttctaataga tcacgtagac cgatttctcc tgttgcgata gggattagaa
    24181 tagccgctgt gatgatcgtc accccaatat tgattccttt gccttgaagc caagggaaaa
    24241 aggaacggga ggctggtatg agcttcataa tcaaaacaaa agctgccgct atcatcagac
    24301 tttgattttt agctaaaatt gctacaagta aaataattcc taaaaaaagc caactttcca
    24361 tgaaatatat tcctcacttt cttcgaaaca atcataacat gtttttagaa agttacaaaa
    24421 gtaggaattc atccttcaag acctattcat aagctgtttt tttcataaaa taaacaaaat
    24481 cataaaaaaa cactttgctt atttgacaga agacagccgc gctttgtata gtggacaaga
    24541 cttacatttt tttgaagaat cagaaagatc aggtaaaggt cttagtaaac gcaagccatt
    24601 cagaataacc aatattgtgc ttccttcgtg tcctacaact ccaagaggta gatttaaaaa
    24661 ttgcaggaag ttagaagcaa tcaacaagag aataacaaga atcgaaaaaa taatattttg
    24721 tttgatgatc cgccgcattt ttaaagatag ccgatgactg tagacaaatt tatttaagtc
    24781 gcttttcatt aagacgatgt ctgcgatatc catagcggca tctgtccctt gccccatagc
    24841 gacacctaaa gaagcggctg ctaaagcagg cgcatcattg actccatcac caaccatcgc
    24901 atttacttgg taaagttcat tctctttttt gactagttgt gttttttctt ccggagtaca
    24961 gcttgcatag taatgttcaa tccctacttg ttcagcaatg gcctttgctg tgccagaatg
    25021 gtcgccggtt atcatacttg tatggatgtt ttgggattta aagtaggaaa ttacttgttg
    25081 ggtatttgct tttggaatat ctagcagacc taaaacagca attaactgct gatctttaga
    25141 aagataaatc acggttttgc cttgattttc caaacgttcg atcatttccg caatctcttt
    25201 gctgattatc atcgtctcag gatcatatgc gtgcttgcca actttccatt gcgcacctaa
    25261 ataggtagtt tgtaatccaa aaccagtaat ttcttctatt ggtaagtatt ggatttcttc
    25321 aggtattgtg caatcgaaat attgcaaaat cgcatgagca agtggatgcg tcgttttttg
    25381 ttccatagca acaagaagtt gttgtgccaa atccttttca tcaaagaaaa agctgtcagt
    25441 tacaactggt tttcctttag tgagcgttcc tgttttatca aaggcaatcg cttttaattc
    25501 agaaagcttt tctaaatgga taccgccttt gattaaaatc ccattttttg cagaatttga
    25561 aagagcagct agagaagctg gtgtagcaga tgcgacaagc gcacaaggag aagccacaac
    25621 taataatacc attcctcgat aaaagctttc atcccaactc caacctagga aaaagtgggg
    25681 gagaaggatc attagaggaa cagcaagcaa aatcaatttt acataattat tttcgattcg
    25741 ttcgataaat gaagctgttt gagttggcgt attctgcgct tcttctacta attggataat
    25801 cttagcaaag acagtttcgg aactcgtttt tgttactcga atcgtgatgg gatttccttg
    25861 attcagcgtt cctgcataca tctcatcgcc taaatatttt tctacaggca cagattcacc
    25921 gcttaatgca gactcatcga tcgttgcctg tgtgctttct aaaaagccat ctatcggaac
    25981 agctgctcct ttagcgacaa ataccaagtt atccaccttt agttgagaaa catctacttc
    26041 ttgcatttgt ccattttctt ttaataattg ggctttttgt ggttgaagat tcatcaaagc
    26101 agtaatttct ttttgacttt tattagttgt gtattcctct aatgcaccgc ttaaacaaaa
    26161 gatgaatgtc aacattgctc cttcaaagta attaccgatc aaacaggcac caatagcagc
    26221 taaagccatc aataaatcca cattcagtgt ccgatcattc cacaattctt tcaagccttc
    26281 cgatgtttgt ttatatccac cgatgataat ggcactgata taaaaaagtg gggtgatggt
    26341 aagagagaat cggtcgaaga taaaaccgaa gatcataaat aaaaggcagc cgattgttgc
    26401 tgcaaaagct tttttctgat tagtcatcgt tattagacct ccttgtcaaa acaaggatag
    26461 cataataaaa atgtaattga taataataac agctaaatga gaacgataat ggttatcatt
    26521 tggtgattaa gcttgatgtt gtttttatta tttataatga ttattattaa agaaaataaa
    26581 aaaccagaac atttctcaaa taagagaagt gttctggttt tttctacatt gcaataaacc
    26641 aataaccaat caaaatgata ccaaggataa tacgatacca gccaaaagcg gtaaagtcgt
    26701 ttttcttcaa atagcttagt aagaatttga tagctaagac ggaaaccaca aaagatacga
    26761 atgttcctac aagaagaaca acagtttctt ccattttgaa tgaattccct tcagctaaat
    26821 atttgacgat cttcaagccg cttgcgccaa acatgacagg aatccctaag aaaaatgaaa
    26881 actctgtagc gacaaaacgc gaagcaccaa tcaagataga tcctaggatc gttgcgccag
    26941 aacgggatgt tccgggaaca agtgccaaga cttggaataa cccaacaaga agagctgctt
    27001 ggtacgtaaa gtcattcaga gaagtccaac gaggtgtttt gtttttgttg cgtttttcga
    27061 caataataaa ggcaataccg taaacgatca aaacaatggc aactggtaag aacttgtgga
    27121 aatttgcttc taaccaatca tccaaaggca aaccaatgat gatggctggt atgcaagcaa
    27181 cgatcacttt aaaccaaagt gtccacgtat cttttttttc taccgttgat ttacttggag
    27241 aaaatgggtt taacttgtga aaataaagaa cgacgacagc caagatcgcc cctaattgga
    27301 taacgacatt gaacatcgac ataaattgtg aactggcatc cagtttgatg aattcatctg
    27361 ctaggatcaa atgaccagta ctactgatgg gcagccattc cgttattcct tcaataatac
    27421 cgagaatcac tgctttgata atatttgcaa aaaacataaa ttccttcctt cccaattaag
    27481 atacatctta tagtataccg ttattttttg agaaacccaa tctgtttttt aatattaaga
    27541 aaaacttgag aaataaagca gataagtaca cgaagagaaa aaagaagaca aagccctcgt
    27601 tcagactttg ccttttatga ttctctggta aaaattaaaa tatccccatt atagaaacga
    27661 gtcgcgacta tgtgttttcc cgttatcgat ataagacgta tcattgatgc cgtggataga
    27721 aaatcgaccg tttgcataag tgacctttgt tacgctgcca tttaaaagcc cagcacgaac
    27781 aggctgttta ggatcgatca gattaagcaa aaaggcgatc gtcaaaccat gagatacgac
    27841 taaaacattt ccaccaccat ttttttcgca gtgatgggcg atatcttcaa atcctgtcca
    27901 tacacggtct cgcaatgttt cataagtttc cgcccaccca gcggtatcta agttgtatac
    27961 agcattagca atttgttcaa aagaaacttc tgtggtaaac atttcatcat atgttttaaa
    28021 attcaataca cgagggatca caccccacat ttccatgtca tatccacctt caagagaccc
    28081 gaaacaccat tctctaatcc ttttttcaat aaaataagga atttcttttc ccttagaatg
    28141 ttctcctaga ataatacggg cagtttcgat tgcacgacca ctgtcactag aataagcaaa
    28201 tgaaaagtcg acatttttta acccgcgacc taaataatga atgccttctt gtccttgctt
    28261 tgtgaggggt gtatcacacc agccttgtac tcgttcaatt gtattgaaca tcgtttttcc
    28321 gtgtcgtacg atataaagtg tagtttctgt cattttattc tcctcctaag tcgttttaac
    28381 gattgaaaaa aggatttgtc cttttttcct gttcaatcgt cgttgcatcg ccatgtcctg
    28441 gatagactgc aaattcatca ggtaatacaa acagctgggt ccgaatacta tgaagtaatt
    28501 gttctaaatt ccctgtatac agatcggttc taccgatact tcctctaaac agggcgtcgc
    28561 cagaaacgac aaaatcatca aaaataaagc tgacgcttcc tatagaatgc cctggggtag
    28621 ggacgacgcg aaaagacatg tttcctaaag tataagtttt catttcaaat tcatattctg
    28681 caggcgagac aataacatca gcaatatcat catgtctacc gagtccagaa agattcaaaa
    28741 tcggatcacc tagccatttt tgctctagtg ggctgacata aactgggatt tgataatacg
    28801 cgcgtaaagg ttccactgca ccgatatgat cgtagtgagt atgggtaagc aaaatcgcta
    28861 ccggctgttg gtttgttttt ttgatttctt gtttgattcg ttccgcatct tctccagggt
    28921 caatgatcaa aagtgcttct tcgttgtaga ccaaataaca gttttcttca atcattcctg
    28981 tttttaatct ttcgatatgc atgtgcattc ctccttgata gccaaaactt ctttcatcca
    29041 ttagtataac gcattcattg ctaggaaaca aaaacaggta cttatttctc tttacttatc
    29101 tgaattatca gactatatga aaagtatttg gatattctaa agagaaggaa agtaagtttt
    29161 catagcattt taatatgtcc ttgttacatt agattcatcc aaaaatccaa attctatatc
    29221 ctatatccct gcctaatcag cagggtgttt ttttatgttt ggaaagagag ctctttttgc
    29281 taaactaggt tttttcaggt aatcttagag agaaagaggt ggtggaaatg atcaaacagt
    29341 caaaaatatc tgtgcggcac ttagtagaat ttattttgcg acgtggaagt atcgacaatc
    29401 gtaaaaaaag taaccatact gcattagaag gagcgagaat ccaccgcaag ctccaaaaag
    29461 atgcgggaga aaactatgaa aaagaagtct ttttaaaaac aacagttcaa ttagatgaat
    29521 attacctgat cgttgaaggc cgtgcagacg gtattttcaa aagagacggt atttattata
    29581 tagatgaaat caaaacctcc gaaccacgat ttgaagattt agaaccagaa caagtggaac
    29641 ttttctttca tcaagcaagg gtgtatgcct atatctatag tcaagaacat gatttacaag
    29701 aaataaatct gcaattgact tacttccaga cggcagaaga agtgatcacg agaaaggttg
    29761 aacatcagac aagagagcag ttagaaactt tttttaaaaa gctgactgaa gattataaag
    29821 aatggcttgt ttttcaagaa aactggcgca ctgtacgcaa tgcctctttg atggctttga
    29881 aattccccca tgatgagtat aggaaaggtc agcgtgaact agcggtagct gcttataaaa
    29941 cgatccgtac gaaacagaaa ttgtttgtag aagcacctac cggaacagga aaaacaatct
    30001 ctacgttatt ccccgctttg aaagctgtag gggaagaaga gggagaaaag atcttttatc
    30061 taacggctaa aacaataact agacaagtag ctgaagatgc tatgacagca ttaaaagata
    30121 caggagctga agtaaaaagt gtcactttga cggcgaaaga caagatctgc tttttagatg
    30181 agacgacctg taatccagat cagtgcccat atgccaatgg ttattacaat cggattaatg
    30241 aaggtttatg ggatcttttg aatcatgaga atcagatcac tcgtgaagtc atcgaaactt
    30301 atgcaagaaa gcatacactt tgtcctttcg aactatcatt agatgtcagt atctggtgtg
    30361 acgtaatcat tggggattac aattatttat ttgatccaac tgtttattta agacgttttt
    30421 ttgaagatga aaaaaacgag gactatctgt ttttgattga cgaagcacat aatttggtga
    30481 atcgttcccg agagatgtat tcggcagaac tatcttatga aaaaacgaaa cgaagtaagg
    30541 aagctatacc aaaggaattc aaaaaacttc atcgccgttt caacaaacta ttaaaagaat
    30601 ttgattcgat ccgagaaata gcaaaagaag atcattggga ttatcatcat caaaaagcac
    30661 cggctgaatc tttagtaaag gcaggttatc aattaagcga aaaaattaaa gaatggctgg
    30721 cagaatttcc tgagcaccca tcacaagaac aattgcttcc ttattatttt gatttgcttc
    30781 attttttgaa ggtcagtgaa ttttatgatg atcactacga aacaacagtc gaaaaaacgt
    30841 atcgcgatct gatagtaaaa gagttttgta ttgatccaag cttgtttctt gagcagtcgt
    30901 tggataaagg aaaaagcagt attctttttt ctgctagttt ttcaccactc tcttattatc
    30961 aggaaacact ggggggacaa aaaagtctgg cttacaaact gccgagtcct ttcccagaag
    31021 gaaaccagca agttttcatc gcaaattacc tagagacgac ttatcgaaaa agggaacaca
    31081 gtctggcaaa attagtagag acgattcatg cttttgctga tggaaaggtc gggaattatt
    31141 tcgttttctt tccttcttat caatatttag atcttgcggt ggaagcattc agacagcaat
    31201 atcccgacag caatgtgcta atccaagaaa cggacatgaa tgaggaagaa cgcgaacgat
    31261 ttttaacaaa atttcaaaca aatcccgctg aaacattgat tggattttgc gtacttggcg
    31321 ggattttttc agaaggaatc gatttgagag gggaccgatt gatcggcagt atgatcgtag
    31381 gtgtaggttt gccgcagatg aatcatgagc aggaactgat caaatcatat tatgatgaga
    31441 aggaacacct tggatttgct tacgcttatc agcttcctgg aatgaacaaa gtcttgcaag
    31501 ctggtggtcg agtgattcgt ggcatggcgg atcaaggaat cgttgtattg gcagatcaac
    31561 gattttctag tttttcttat cgacgtttat tcccacaaca ttggcaaaca gcaagagaag
    31621 tacgaagtgt tggggaattg gaagaaggaa tacagcgttt ttggttatca aaagaagcag
    31681 taaatcaaaa aaacgaggaa tgacagacgt cagcctcgtt ttttgattaa cgatagttag
    31741 tgaattgcaa ctcgattggt aagtcaagtt tacgtaataa agcaatcaca gcttgtagat
    31801 catcacggtt cttacctgtc actctaatct gatcttcttg gatttgtgct tttactttca
    31861 gtttttcatt tttgatagct gtagtgattt tcttcgcgtt ttcacgatcg attccgttga
    31921 ccaaatcggc agtttgtcga gctttgccac ctagagcgtg ttctgattcg gaaaaatgga
    31981 tatttttgat tggcacattt cttttgatca gcttaccaaa taatacatct ttgatctgtt
    32041 cgattttgaa atcatcatcg ctcaatacaa ctagattgct gttctctaat ttgatttcta
    32101 ctgtagaatc cttgaagtca aagcgattgg acaattcttt tgttgtttgc tgaatcgcat
    32161 tttttacttc ttctgtattg acttctgata caatgtcgaa gctagcatct tttgccatag
    32221 gaaccctcct gatatacata taaatattta ccatacatct atcttatcat aggattaggg
    32281 cagattctta cctgtttgct aaaattcttc tcatttgagt tcgaagtatt ttattttaat
    32341 agataaactg ttattcttac atttggaata ccaaagtagg ggagaggtgc ttgtgagtaa
    32401 aattatgact gcgtatcata aaaatgaaag attaaagaaa atagtggtta ttttgataac
    32461 cggattgacc gctgcggtcg ctttaaatta ttttttgatt ccagccaatg tcttttctgc
    32521 agggatgaat gggatcgctc aaatcatttc ctcgctttta tatgaatggt ttcatatcaa
    32581 gatagacaca ggaacattta tttttctttt gaatatccct gtgtttgtat tagggtttct
    32641 caaagtagga aaacgagcaa cgatccttag ttttgtgaat gttgtatgtg tatcggtgat
    32701 gacgatgctg cttccagtcg gacagatcac tgataatatt ttgatgaatg ccctagtagg
    32761 cggtgtttta ttaggtcttg gcgtaggatt atctttaaaa atgggcttta caactggtgg
    32821 gatggatatc atctctcttg tactttcaca aacaactgga aaaacagtcg gaaactacat
    32881 gctgattcta aatggtatca ttgtagtcat cgcaggcttc ttctttaact gggaaagtgc
    32941 cttgtatacg attatttcca tttatgcaat gactcaagta attgatgcca tccacacgag
    33001 tcatcaaaaa gtaacagcaa tgatcgttac cgtcaagcca gaagaggtaa cagaagaact
    33061 agcaaaacgg atggtacgtg gaatgacatt actgccgtct gtcggtggct attcaaaaaa
    33121 acaagggaac atgatcatga tggtcatcac ccgctacgaa atgtatgatc ttgatcagat
    33181 cgttcatgaa atcgacgacg atgcatttat caatatttta ccaactcatt cagtatttgg
    33241 ccggtttgca aatgaaaacg aacaaaaaat gtatcgaaca actggcgtat tgccagaaat
    33301 aaaaaatcgt tcacaaaaaa aatgaggaat caggtttatt ttagaataaa tttaatctat
    33361 tacatctaat aagaacattt ttataaattt aaacgagaat cttacttcta aattctcatt
    33421 tacaagcagc taaaaaaaga gtatgataaa taaaaatcgt gttaaggagt gtcgtacgat
    33481 gagcgaagca aaccaagaac ggtctggaca agaaatagaa ctaatcaaag aacgtattct
    33541 tgctgccttg gaaatggtga ttgatcctga attaggaatc gacatcgtca atttaggctt
    33601 gatttatgat atagaattca atcctgaaaa tggagaaaca gtcattaaga tgactctaac
    33661 aactatgggc tgtccattag cagatatttt aacagaatct atccatgacg cattaaaaga
    33721 agtgccagaa gtaacgaaag cagaagtcaa actagtctgg tatccagcat ggacgacaga
    33781 taagatgagc cgttatgcac ggattgcgtt ggggatacga tagaaatctt ggctgactag
    33841 ctatgagaag caaataggaa aaacaaaaaa gccttttatc ctttctagaa gaaaagagat
    33901 aaaaggtttc tttgtttata aaattttgtc tgctatatta taagttaatt aaataaatgt
    33961 gttctattga taaaggacat tcaaatccct ttccttttgg aatccttctt ttttacatca
    34021 gtttgatttt cgtatagtat tctttctcat cttcacgata aatcgcagcc ccattttttt
    34081 gttgtgcttt aagactgcca agattttttt tatttacaga caaaagtgcc tcatcaatgc
    34141 cgattttttt tgcctcttgt agtactaatg ctaatccttg tgtggcatat ccttttttac
    34201 gataattagg ggagatgccg taaccaatat ggccagcgcc gtttcttaat gtttcgttca
    34261 gtttatggcg caaattaaaa attcctacat actcatgttc atcactttct aaaataaaga
    34321 cggttgcggg aacgtaactc tcaggaagat cgattcctaa agacgttttt tcgcattttt
    34381 ttacataatc taaaaattca gcaaatgtat agccataagc attgttgata aatccactct
    34441 catttggtcc aaagctagtt tgtagctgat aagctttctt taaatctgct tcccatagtt
    34501 tgatcagttt catcgtattc acctctttaa gtaaccttat tcatttgttt tctactatag
    34561 cactattgtt gtaaatagcc atgcctattt ttatttattg tgtcatatcg tattaagaat
    34621 catcgaacaa tacaaatatg aattacaata aaaaaattat ttgaagttcg ttcattcgtt
    34681 acttatgatc tctagaagaa agaaaacgtg aattacttca gcgtctagaa ttccagaagg
    34741 atagtaatca acagaagaaa taatcaatat ccaaatgaaa gaagatagct gaatcgagaa
    34801 aaagaggaaa aaagaaatga agaaaaaaat aaaatagtta ctaatcccag agtcgttcgt
    34861 ttaacattga aatcgatcat atggataaaa cagatttttt caccaaccct caatagatga
    34921 tggagttgct cggatgaatt atttgtgtag atggcataag ggagggcgta cagaaatgaa
    34981 aaagaacaaa aatatgttct tgacaaaaaa cacatgtaat cctaaactaa aagatgtgat
    35041 gcggctatgg cggaattggc agacgcgcta gcttcaggcg ctagtgaggg tgacctcgtg
    35101 gaagttcgag tcttcttagc cgcataattt gtttttttat aaagagaagg tacacctgga
    35161 gcgatgagaa agaaaataac atattatcta aaagaatata ggaaaaattt taaacaacgg
    35221 aaccagattc aaataaatca aaaaaaattt gtgtgaaggt gggacagttt aaaacctaat
    35281 agattgattc aaatagtaga tttatagatt ctgatacaag aaatactggc aaacgatagt
    35341 taaggaataa agactaaact taaactcaaa aagaggtcat gcgaaagaat aaatcgcatg
    35401 acctcttact atattttgaa tgtgtttaaa cgttcaaata atgaatctta gtaccaaccg
    35461 tttgcttccc agaatgcttt cgccgcttcc caagaaccat aacgtgaagt aacatattgt
    35521 tctgctactc tttcttggtt tgcagcagag tagtcaccat ttaagtaaga agaatctaat
    35581 tggtaacggc cgatgtaacg tccgttcgtt gctgtgtaag aaccgcttga ttctttttgt
    35641 gcgatccatt cttttgcaga gcttgtactt gctggagtag cagcagtttc tgttacagca
    35701 ggagcaggtt gtgtttcagc aacaggcgct gcttgtgttt ccgtttgaac cgtttcttgt
    35761 acaacaggtt gttcagcttg aacaggttca gcttggactg gtgcttcttg aacggctgct
    35821 tgaggttcag cagctgcttg tgcagagcct tctgttggga ttgttaattg ttgtcctgag
    35881 ta
//
LOCUS       DAFLVO010000023        34955 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.023, whole genome shotgun sequence.
ACCESSION   DAFLVO010000023 DAFLVO010000000
VERSION     DAFLVO010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34955
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.023"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            156..1862
                     /gene="efbA"
                     /locus_tag="L1U99_001184"
     CDS             156..1862
                     /gene="efbA"
                     /locus_tag="L1U99_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HBN1211736.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2020..2922)
                     /locus_tag="L1U99_001185"
     CDS             complement(2020..2922)
                     /locus_tag="L1U99_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1211737.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2919..3611)
                     /locus_tag="L1U99_001186"
     CDS             complement(2919..3611)
                     /locus_tag="L1U99_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HBN1211738.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3654..4295)
                     /locus_tag="L1U99_001187"
     CDS             complement(3654..4295)
                     /locus_tag="L1U99_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBN1211739.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4333..4647)
                     /locus_tag="L1U99_001188"
     CDS             complement(4333..4647)
                     /locus_tag="L1U99_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211740.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4635..5987)
                     /locus_tag="L1U99_001189"
                     /pseudo
     CDS             complement(4635..5987)
                     /locus_tag="L1U99_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372436.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
     gene            complement(5984..6916)
                     /locus_tag="L1U99_001190"
     CDS             complement(5984..6916)
                     /locus_tag="L1U99_001190"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBN1211741.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6913..7689)
                     /locus_tag="L1U99_001191"
     CDS             complement(6913..7689)
                     /locus_tag="L1U99_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBN1211742.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7743..10928)
                     /gene="carB"
                     /locus_tag="L1U99_001192"
     CDS             complement(7743..10928)
                     /gene="carB"
                     /locus_tag="L1U99_001192"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBN1211743.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10933..12009)
                     /gene="carA"
                     /locus_tag="L1U99_001193"
     CDS             complement(10933..12009)
                     /gene="carA"
                     /locus_tag="L1U99_001193"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBN1211744.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12014..13294)
                     /locus_tag="L1U99_001194"
     CDS             complement(12014..13294)
                     /locus_tag="L1U99_001194"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBN1211745.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13313..14239)
                     /locus_tag="L1U99_001195"
     CDS             complement(13313..14239)
                     /locus_tag="L1U99_001195"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HBN1211746.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14252..15535)
                     /locus_tag="L1U99_001196"
     CDS             complement(14252..15535)
                     /locus_tag="L1U99_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBN1211747.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="L1U99_001197"
     CDS             complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="L1U99_001197"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBN1211748.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16323..17234)
                     /locus_tag="L1U99_001198"
     CDS             complement(16323..17234)
                     /locus_tag="L1U99_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBN1211749.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17231..17695)
                     /locus_tag="L1U99_001199"
     CDS             complement(17231..17695)
                     /locus_tag="L1U99_001199"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBN1211750.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17700..18398)
                     /locus_tag="L1U99_001200"
     CDS             complement(17700..18398)
                     /locus_tag="L1U99_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBN1211751.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18385..18771)
                     /locus_tag="L1U99_001201"
     CDS             complement(18385..18771)
                     /locus_tag="L1U99_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211752.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18918..20588)
                     /locus_tag="L1U99_001202"
     CDS             complement(18918..20588)
                     /locus_tag="L1U99_001202"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBN1211753.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20771..21004
                     /locus_tag="L1U99_001203"
     CDS             20771..21004
                     /locus_tag="L1U99_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HBN1211754.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21103..21534)
                     /locus_tag="L1U99_001204"
     CDS             complement(21103..21534)
                     /locus_tag="L1U99_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HBN1211755.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21613..22026
                     /locus_tag="L1U99_001205"
     CDS             21613..22026
                     /locus_tag="L1U99_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HBN1211756.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22064..23212)
                     /locus_tag="L1U99_001206"
     CDS             complement(22064..23212)
                     /locus_tag="L1U99_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBN1211757.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23334..23930)
                     /locus_tag="L1U99_001207"
     CDS             complement(23334..23930)
                     /locus_tag="L1U99_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBN1211758.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="L1U99_001208"
     CDS             complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="L1U99_001208"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBN1211759.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27160..27591
                     /locus_tag="L1U99_001209"
     CDS             27160..27591
                     /locus_tag="L1U99_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1211760.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27636..28985)
                     /locus_tag="L1U99_001210"
     CDS             complement(27636..28985)
                     /locus_tag="L1U99_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBN1211761.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29055..30218)
                     /locus_tag="L1U99_001211"
     CDS             complement(29055..30218)
                     /locus_tag="L1U99_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBN1211762.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30347..30670
                     /locus_tag="L1U99_001212"
     CDS             30347..30670
                     /locus_tag="L1U99_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211763.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30853..32202)
                     /locus_tag="L1U99_001213"
     CDS             complement(30853..32202)
                     /locus_tag="L1U99_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1211764.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32271..33224)
                     /locus_tag="L1U99_001214"
     CDS             complement(32271..33224)
                     /locus_tag="L1U99_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBN1211765.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33326..34516)
                     /locus_tag="L1U99_001215"
     CDS             complement(33326..34516)
                     /locus_tag="L1U99_001215"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HBN1211766.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
BASE COUNT         9949 a         7639 c         6119 g        11248 t
ORIGIN      
        1 acctaaaaat ttggatttca acgatagaaa cactgttttt tatgtaatta gtccaagatt
       61 tttctagact tttgctttac tattcggcca aattggtttt tcttcttttt ttcgttataa
      121 tgaatatact tatgaaaaga aatgaggaat gaaccatgtc ctttgatggt gtatttaccc
      181 acgcgatggt caacgaattg cgtgaaacgt tactatctgg ccggatctcg aaaatccatc
      241 agccttatga aaatgaaatc gtgctggtga ttcgttcacg cggcaaaaac catcgattat
      301 tattatctgc gcacccaagt tatgctcgtg tacagattac ccaaatcgat tatcagaatc
      361 ctgataatcc gcctaacttc gtgatgatgc ttcgaaaata tttggatggc gctattttag
      421 aagacatcga acaaatcgaa aatgatcgag tgatccattt ccactttgct aaacgaaacg
      481 agttgggtga tctacaaaat atcatattga tcgttgaatt aatgggacgt catagtacga
      541 tcgtcttagt taatcgagaa actggaaaaa tactggatgc gatcaaacac attggaagct
      601 ctcaaaacac ttatcgttct ttgcttcctg gtgtagaata tgttgctccg ccaaaacaag
      661 aggtcttgaa cccatttagc tccgagaaag aaaaaatctt tcagcggctt tcccaaactg
      721 aactagatcc aaaagcaatc caacgtcagt ttcagggaat cggtttcgat atcgctcaag
      781 agctgaccaa aagattactg gaacgtccta atgaaaagat ggttgtatgg gacgaatttt
      841 tctcagccat cagccatcag cctattccta ctttttacga aacggaaaat aaagattttt
      901 tcacaccgat tgcttatcag gtattgtccg aacaggcatc tgctgtaaca gcttatccaa
      961 cactcagtca attattagat agctattatc acgaaaaagc agagaaagat cgggcaaaac
     1021 aacaaggcgg agaactgatt cgaaaaatcg aaaatgaact aaaacgaaat aaaaataaat
     1081 tgaaaaaacg tgaacaaaca ctcaaagaat ccgaaaacgc tgagaattac cgtagaaatg
     1141 gcgaactact tactactttt ctgacacaag taccacgcgg cgcaaaagaa gttgttttac
     1201 ctaattatta tgaagaagat cggccaatca aaatagcact agatccggca ttgacaccaa
     1261 atcaaaatgc acagaaatat ttccatcgat accaaaagct gaagaacgct gttaagctga
     1321 ttggcgaaca aatccaagaa gccaaagatg aaatccaata tcttgaatct gtcttatctc
     1381 aactggaaat tgccggccca atggatatcg aagcaattaa agaagaattg acttcagaag
     1441 gatacctgaa aaagaagaac ttaaaaaaac aaaaacgtaa gaaaccatct cagcctgatc
     1501 aatacttttc ttctgacgga acgctcattc ttgttggtaa aaacaatctt caaaatgacc
     1561 agctgacaat gaagacagct aaaaaaaccg actattggct tcatgcaaaa aatatacccg
     1621 gttcgcacgt catcattaaa agtgacaagc cctcagatga aacaattaca gaagctgccg
     1681 agttagctgc ctatttttca aaataccgat actctgccca agtgccggtt gatcttgtac
     1741 aggtaaagca tatccgaaaa ccaaatggcg ccaagcctgg ttatgttatt tatgaaaacc
     1801 aaaagacgat tatcgtgaca ccagaagaag aaaaaattac agctatgaaa caaaacaggt
     1861 aatcaatgag tgtttctaga atcatatttg cgtactttcc cacaacagca attagttata
     1921 aattgtttgc tacaaaaaga ggagttgtga caaaattctg tcacaacccc tcttttttga
     1981 tcaacggtgt tcaataaaca gcgttctcat ctgcttttct tagctctgct ggtccagtaa
     2041 ccgagtaagc tctttgataa atctttgagc gatttcactg agcggacgtt tcgccgaata
     2101 aatgatataa aattcattta gttcgccttc tgccaaaggg attaaccgca agtgctcgcg
     2161 aatccctcca atcacaatac cagatcctga agcgtaagca tcagtttcaa gaacgatatt
     2221 catcaaagta cctcgatcac tcgtataaat cactgtttct tgatcaggga tctcgataag
     2281 gtcttcataa aaatacggga aattatttcc atcctgtgta aaacgaactt gaggataaga
     2341 taacaattct tctttggtga tctctgcgtg ttcagctaat ggatgtcctt gccttaaaaa
     2401 aatatgcgtt ttgaattttc caatgctgcg gccacttagc tctccttgtt gtaaatatct
     2461 tctgatacca gcttgattat gctcattcat ataaataatg ccgatctcac tgtgctgctc
     2521 tttgacttct tcgatcactc tcgctgttgt cgtctccatg atccgaaatt gtttgatctc
     2581 gtctttgaat tcctcgagta gctgtgcggt caaaggacct aagaaatcat aatgctgggc
     2641 agcgatcgaa aaattgtctc tcttttcact cgttagatag tgagtttcta atgtatcaag
     2701 ctggaccaat attttctcgg cacgatttaa gaagtcttgc ccttcttctg ttaaatatgc
     2761 ccctcgattc gttcgagtaa acagcgtgat ccctaactcg gtttctaatt ctttgatacc
     2821 agctgaaaga cttggctggg agacaaacat tttctttgcc gcttctctga aactaccatt
     2881 gtttgctaca gcgaccacgt atttcatctg ctgaatattc attgctcaaa ctcctcgaaa
     2941 taataaattt ctcttccatt caagggctgg attggtcggt tgttcggtcg agcatactga
     3001 ccatcgaagg ggagaagaaa ctcttggttc agttttccta catgatccat tacaaaccat
     3061 tggattggcc cgctggtagg cggagttgtc aatgagccaa tataatggaa atggcttttt
     3121 tgctccggaa agaacacatc cggatttacc caatgctcat gtttttctaa gttccaactt
     3181 tccccatttt cttgattata cagccaacct tcctgtacca ttagctggta catgacaccc
     3241 acaactagat tctctttttt gctgttcata tgaacaaaat gaaattcaat atcttcctgt
     3301 tttccgttga tgatatgttc agaaggcaag tggaaatgaa tatctgtcaa ataatagcgt
     3361 tctttcttga actctacata actgagttgg tcaaaaggta ctaaatgaat cgtgtttttg
     3421 aattccttgt cagtaaaccg ttgcttttga taatgaaagg aaagcgtgtc tccttctatt
     3481 ttggtttctt cccccttggt caaatgaata ggcgactgca atggaaattc cgcacctctc
     3541 gcaaaccaat cacataaact cgcccaattt tccggacctt tgtctccaga atagccccat
     3601 tcgacatcca tattcttttt caactatact tccccctgca tctcatatca tttttatttt
     3661 tcttctttct ttacaatcgt tgagacggtt tctaaaaacg cctcttttcc ataaaattcc
     3721 tggttcaata gttccggaaa tatctcttta aagaaatact gaacagaagg ccgatgttca
     3781 aagcttttaa tcgtagtcac tgcctcaatg aacatctcct tataaacttt ttccgggtta
     3841 tttttgatga tttcatcaaa agattcataa agaaggtcaa ccttatctga aatggctaat
     3901 agttctcctt ctacggtttc atcttttcct tcgaacaacc gacggcgata aacttcttgg
     3961 aactcagctg gaatctcttg gttgatgaat tcgtccgtca tcttttcttc aactgtttgc
     4021 agcatccctc ttaactcttt gcttgcgtat ttcaccggcg ttttgatatc accaataaaa
     4081 cgctctgtgt agtcatgatt caatgatttt tcatagagca gtttccaatc gatcggttgt
     4141 ccattcgctt cttcaatgtc tcctagaact tgcgcaatag atgctacacg atacgaatgt
     4201 gctgcaactg tatgctctgt atatttaaaa aatccaggtg cccttgtgat cgtctctaaa
     4261 ttgttcaatc ctaaaataaa ttcattcaac cccataaaag ttacctccct ttgagatttc
     4321 tttttccgaa tatcatatca ttaaataact gatattcgca acatttccgc tctttaccat
     4381 ttttgaaaca gctcccttac caaaaaatag agaaaatcta tatataatag aaaaaagaga
     4441 agagattatt ctcttctttc tgctaaccag tcttagaaaa atgaatttta aaaaaatcaa
     4501 aaactgatca cgatagaagt ttcttttcat acctgatgaa aagatgcttc tcgcaatcag
     4561 tttttggatt tttgctattc caattgatga ttctggagac acaaatcgga tttctctatc
     4621 ttcatcaagc gcgcttaaat ctgccaattt tcaggatctt ttttccattc ttttagcaga
     4681 gttaattctt gctcatcgat ataacgatct tctaaagctg cttcaatcaa tacagaataa
     4741 ttggtcaacg tcataagagg gatttcggct ttttcgaaat ttgcttttcc ttttggcaac
     4801 tcatacgtaa agatagccgc aacaccaagg atatccgcac cttctctttt tgctgcttca
     4861 gctgcttcca agacacttcc gcctgtagaa atcaaatcct cgatcacaac catcttctga
     4921 ccttcaaata tacgtccttc gatttggtta cctttcccat gatctttcgc cttacttcga
     4981 atatagacca ttggcaaatc cagtatttcc gctacccatg cggcatgagg gattcctgct
     5041 gttgcagttc cagcaatcac ttgtacttca gggtaagctt ctttgatttt gcttgctaat
     5101 ccttttgcga tctcttttcg gacttttgga tagctcatcg tgattcggtt atcacagtaa
     5161 attgggcttt tgattccact tgcccatgta aaaggattac ttggatttaa aaatactgct
     5221 tcaatttcta ataagtcttt tgcgatactt tgttcaacat tcattttagg ttagctccat
     5281 tctgtttgaa tcgtttgata tgctttataa ggattagttg actgagtgat tggtcgacct
     5341 ataacgataa aagttgagcc gatctttttt gcctgagaag gtgtgactac tcttgtctga
     5401 tctcctgcga ctgttccttc tggtcttata cccggagtta agcaaacaaa ttcgtctcct
     5461 gccatttctt tgatcgcttc tacttcccaa gcagaagaaa ccacaccatc taatcctgct
     5521 tttttggcac agctagcata atggatcaca cttttttcta aagaaacttc gattagttga
     5581 tcggcatgca tttcttcttc acttgtagaa gtaagctgag tgatagctag aagtagcgga
     5641 cgttttccac cttctggagt cccctcttct aatcctcgca ttgccgcctc catcatacga
     5701 ataccgccag cggcatgaac acaggtgaga tcaacaccaa gctttgccaa tccccgcatt
     5761 gctttttcga ccgtattcgg aatatcgtga agtttcagat ctaaaaatac attatgacca
     5821 gcctctttta gataacgtac gatttcaggt ccttcttggt agaacaattc cattccgatt
     5881 ttcacaaaca atttttcttc tttcgggaaa aatcgaagaa agtcttctac ctcttgccta
     5941 gttgaaaaat ctaatgcaat aattggtcgt tggtctagtt gattcatcgt tcacgttcct
     6001 ctctcacttc tttgattaat ctttccagcg attcgatgcc tagttcgctc attcgcacag
     6061 ggagctcttt aattagttta ggacagatat acggatcggt gaaattcgcg gtccctatag
     6121 ctacagcact tgctccagcc ataaacatct caagaacatc atccactgtc tgcacgccgc
     6181 ccatcccaat gattggaagg ctggatatac ttgctacttg gtgaatcaaa cgaatagcga
     6241 caggcttgat tgctggtccg gagagtccac ctgtttgatt ggctaaaatc ggttttcttg
     6301 tcttaaggtc aatccgcata ccaagaagag tattgatcat cgtaaaccca tctgcccctc
     6361 cagcttcgat tgcctgagcg attggaacga tgtctgttac atttggggac aatttgacat
     6421 agacaggaac agaagaaact ttctttactg cttgtgttaa ttgaaaagca acatcagaat
     6481 ctgttccaaa agcaattccg ccatgtttga catttgggca agaaatgttc agctcgattg
     6541 ctttcacatt tggtgcttcg ccaattttgc tacaaacttc tacatagtct tcttcacaag
     6601 caccagcaac atttgcgatg atgggtaact cattgtactc ctctaattct ggaagaagtt
     6661 tatgcataac aacgtctaga ccaggatttt gcaaaccaat tgcattcaac atgccagatg
     6721 gtgtttccgc cactcttggc gtgggattgc caaagcgggc atttggagtc gttgccttga
     6781 ccatgatcga tccaagctga ttcaaatcat agtattttcc gtattctttg ccaaaaccga
     6841 aacagccgct tgccggcatg ataggatttt ttaattctag gccaggaagt ttgaccgcta
     6901 aaggattctc attcatataa ttacctctcc tattttaaaa atcggtcctt cgtcacaaac
     6961 tttcacactt tttgttcctg tttcatcttc cggcgtatga caaacgcaag catagcaagc
     7021 ccctatccca catgccatgc gggattctaa tgataactgg acattttgat gcgaagaaaa
     7081 cagctgttcc actgtcttca ataacccgtt tgaaccacat gcaaaaacag ctgtaggttc
     7141 cgtcttcgtt cctaacaata aattaccgac atttccgtgc ataccgtatg ttccatcgtc
     7201 agtagcgatt cttgtttctc ctagacgatt aaattctttt tcataataaa cgacttcatg
     7261 tgtggcaaaa cctaaaaaat gcgttggctt aattcctttt tcgactaact gttttgataa
     7321 ctcatataga ggagggacac cgattcctcc accgattata aatacttcgt ctcctgtatg
     7381 aagattggac aaatcaaaac cattgcctaa aggacccatg acatctaaat ggtctccggc
     7441 agaaagagta gagaagactc tagtcccctc accttccacc cgataaatga tacggcaagt
     7501 atttgtttcg tggtcgatat gattcaagct aatcggtcgg cgtaatagca agtctgcacg
     7561 cggcacgaga atatgcaaga actgtcctgg ttgctgcatt tcttttacta gatcaccttt
     7621 caatgtcatt tcaaaaatct ttggtgccag ctgtttttgc tgaacgattt ccatcatttc
     7681 ttgtttcatc tgtcccctcc tgcaacggtt tttcgtcttt ttgtcttaac atgtgctcgc
     7741 cgttaaatag ggttagttga aaaagcacgg gattccatca ctcgaacgat cgcatctgct
     7801 gtgtctaaag aagtaaacaa tggaatacca tgttcaactg cttctcttcg gatgatgaaa
     7861 ccgtctttag aagcatttcc ccgatcttta tcaatcgtat tgacaaccac ttgtgtttta
     7921 ccatctctta ttaagtcgac tacatttttt tctgctgctt cctcagaaat tttcgctact
     7981 gtttcaacga ccagaccatt tttttcgaaa taagcagctg tatgtttcgt tcctatcaga
     8041 ctatagccaa tttctgtaaa acgtttagct aattctagtg cttcttcttt tgtttcgtcc
     8101 gcaatcgtaa ataatacggc tccatattca ggcaagtgta atccagaagc ttcgaatgcc
     8161 ttgtacaaag ctttgtctaa ttgtctgtca gatcccatta cttctccagt cgatttcatt
     8221 tcaggcccta agtaagtatc aactttctgc aatttcgtaa aagaaaagac aggtgcttta
     8281 acatgaactt cttttgtttc tggataaagt ccgttttcat aaccaagtgt ctttagtttc
     8341 tctcccaaaa tagctttcgt cgcaatttgt gccattggaa ttcctgtcac cttacttaag
     8401 aatggaacag tccgacttgc tcgaggattg acttcgatca cataaacctc attttcatgg
     8461 atgacaaact ggatattcat catcccgaca caattcaaac ctaatgctaa gcggatcgtg
     8521 taatcttcga tcgttttctt gatcgattca gataatgttt gaggtggata cacagccatt
     8581 gaatcccctg aatggacacc agcacgctca atatgctcca tgatccctgg gatgagtact
     8641 gtttcaccgt cacaaatcgc atccacttcg cattcaccac caagcaagta acggtccact
     8701 agtactggat gttctggaga tgctttcaca gcatgttcca tgtaatcttc taaatctcgc
     8761 tggttttcaa cgatttccat cgcacgtccg cctaatacat agcttggacg aacaagaact
     8821 ggataaccaa ttctcgaagc gataaccacg gcttcttctt tacttgtagc agtatcccct
     8881 aaaggttgag gaatatccaa ctctttcagc gcttgctcga ataaatcacg attttccgca
     8941 cgatccaagt cttcgatcgt tgtccctaag atttttacac cagcagcagt caaaggttcg
     9001 gctaagttga ttgctgtctg accaccaaat tgaacgatta ctcctatcgg ctgttctagc
     9061 tcgatcacat tcatcacatc ttcgaaggtc aatggctcaa aatataattt atccgaaata
     9121 gaaaagtcag tcgaaactgt ttcaggattg ctgttcatga tgattgcttc gtatcctgcc
     9181 tgctggattg ctttgacaga atgcacagtc gcatagtcaa attcaacccc ttgtccgata
     9241 cggataggac cagatcccag tactagaatt gagggctttt ctgatcgtga actttcattt
     9301 tcatattcat aggaactata aaaataaggt gtttttgatt cgaattccgc tgcacaagtg
     9361 tcaaccatct tatatacagg aatcaaatca ttttcttttc tcatctggcg aacggcttct
     9421 tcgtttattt cccacagctc cgccactttt ttgtctgtaa aaccgttttg tttcgctgtt
     9481 ttcaatatct tgtcatccaa cggctgctgt ttcaactgct gttcgatttc tacgatatgc
     9541 aacagtttat ctaaaaagaa taaatcgatt tttgtcaaat ccgctaattc ttctatggtg
     9601 taccctcttc taatagcttc agctacataa aacaggcgat catcttgtgc tcgaaccact
     9661 ttttggatta ggtcatcgtc cgtgatgtct gccaactcag gaagttcgat atggtgtgta
     9721 ccgatttcta aagaacgcac agctttcaat aaagactctt cgatattccg accgatagcc
     9781 atcacttcac cagttgcttt catctgcgtg cctaaaagcc gttctccgtt ttcaaactta
     9841 tcaaacggcc agcgaggaat tttagctaca acataatcta atgcaggttc aaattctgca
     9901 aaagtcgttc ctgtaacagg atttttcatt tcgtctaatg ttaatccaag cgctatttta
     9961 gcagctagct tagcgatcgg atagccagtc gccttacttg ctaacgcaga tgaacgagaa
    10021 acacgcggat tgacttcaat cacataataa ttaaaactat gtggatcaag agcgagttgg
    10081 acattacagc ctccctcgat cttaagtgct cgaataatcg aaagagaagc atcacgaagc
    10141 atttgatatt catggtcaga caatgtttga ctaggggcaa atacgataga atcacctgta
    10201 tggataccca ccgggtcaaa attttccata ttgcagacaa cgattgcatt atcagccgaa
    10261 tctctcatca cttcatattc aatttcttta aaacctgcaa tacttcgttc aatcaaacat
    10321 tgggtagcgg gggaaagact taatccattt tctgatacga tacgtaattc ttcttcattt
    10381 tcacacatac ctccaccagt tccgcctaaa gtaaaggctg gacgaacgat gacaggatag
    10441 ccgattttat ttgcaaaatc tacagcttct tctactgtat tgacgatttc agactcgggg
    10501 attggctgat tcaattcttt catcaactgt ttgaatagat cacgatcttc tgcttgatcg
    10561 atcgcagaaa gctttgttcc tagaagttct atgttcaatt cttctaaaat acctgatgct
    10621 gccagctcca ttgccatatt gaggcctgtc tgtccgccta aagttggaag gagagcatct
    10681 ggacgctctt ttcgaagaat ccttgataca aattcaagtg tgatcggttc gatatatact
    10741 tgatctgcca cttctttatc cgtcatgatc gtcgcaggat tagaatttac taaaaccact
    10801 tcatatcctt cttcttttaa ggcaaggcag gcttgtgttc ctgcgtagtc aaattctgcg
    10861 gcttgaccaa tgatgatcgg accagatcca atcaccataa ttttcttgat atctgtacgt
    10921 ttcggcatct gtttactgct cctttcctgc gtccatcatt tccataaatt catcaaataa
    10981 atgtagtgca tcatgcggac caggggcagc atctggatga aactgcacac tgaaagcggg
    11041 ataatctctg tgtttgactc cttctactgt tccgtcattt acttctacat gagttacgat
    11101 gagtttttct ggatcaatcg tggcttcatc gactgcatag ccatgatttt gagaagtaaa
    11161 atcaattctt ccggtcgcta cttctcgtac cgggtgattt aatcctcgat gtccgaattt
    11221 cattttatag gtatctgcac cgttggctaa agcaaataac tggtgaccga gacaaatacc
    11281 aaaaatcggt acttttcctt ggattttttt gatcatttcg attgcttctg gcacatcttt
    11341 tggatcacca ggtccattcg tcagcatgac tccgtctggt gatagcgcta aaatcgtctc
    11401 ggcatctgtg ttatagggaa gtactgtgag gttacagttt cttttactca attctcgtaa
    11461 aatactatgt ttcaagccga agtcaatgac aatgactttc cgacctgttc ctggacttgg
    11521 ataaggtttg ttagttgaga cttgctgcac ttgattggtt gctagaacgg ttgctttcag
    11581 ctgatcaaat gcatgttcga aggaatctcc agcatcaact atactagctt tcatcgttcc
    11641 gacttcacgg attttgcgag taagggcgcg cgtatcgata cctgatattc caggaattcc
    11701 tttttgtttc aaaaatgaat ctagcgtcat ttggtttcgc cagtttgaag ctacacgtgc
    11761 atgttctttt actactactc ctttgcatgt tggagaaatc gattcataat catctctatt
    11821 taccccataa ttacccacca taggataggt aaatgtaatg atttgaccgt taaaactttg
    11881 atcagtgata gtttcttgat aaccagtcat acttgttgta aaaacgattt ctccgaagac
    11941 actagcatct gcaccaaaag cctttccttc gaaaactgtt ccatcttcta atataagcaa
    12001 acgttccata cttttattct cccttctgcc acacaagttt tccgttgaca aaagtcattt
    12061 gtgtttcgcc ttttactttc cagccgataa aaggtgtatt ctcccctttt gataaaaagt
    12121 cttctttatc gatcgtgcaa gtttgtgtaa tatcaaaaac tgctacatca gcgggggcac
    12181 caaccgttag cgttcctgca ttcaaaccaa aaatctcagc cggtttaact gccaaccaat
    12241 tgatcacttg ttccaacgtg aatcgaccag tttctacaaa atgagtatag atcagttgaa
    12301 acgctgtttc gcttcctacg ataccaaatg gtgatttcat gaaactttgg cttttttctt
    12361 ctaatccatg gggggcatgg tctgtagcga tgcaatcgat cgtaccgtca agcaagcctt
    12421 cgatcaaagc ttctctgtcc tcccgtcctc ttagcggcgg gttcattttc caaaagccga
    12481 aatcttcggg aatatcttcg tcgatcaaaa taagatgatg gggtgaaact tctgctgtta
    12541 cgtggattcc tgcttttttt gcgtctctga ttacacggac actttcttta gtagaaacat
    12601 ggcaaacatg gtaatgaaca ccagttgctt cagctagcaa cagatctcta gcaatttgag
    12661 aagactcggt tacgcttaag atcccgggaa gaccaagttc ttctgccttc ttgccagcgt
    12721 gcataacgcc gccaaataat aaagattcat cttctgtatg ggctactagg gctttattgt
    12781 tttttgcagc ttctttcata gccagataca tcgtcccagc tgtttggaca cctacaccgt
    12841 catttgtgaa agcaaaagca ccttcttcaa tcagtgcttc ttgatcaact aatttctcac
    12901 ttcgcagatt ttctgtgatt ggcgcatact gcaatacctt cacaactgca tcttttctaa
    12961 tgatgtcata tacttgtctc agcttttctg ccgtatcagg tacaggattt aaattcggca
    13021 tcgcgcatac agtagtgaaa ccgccacgag cagctgagcg agtcccagct tcgatcgtct
    13081 ccttgtatgt aaatcctggc tctctcaaat gaacatggac gtccactaaa ccaggtgtga
    13141 tcaattgtcc ctttgcatca aacacttcat caaattcggc ttctgagaat cctgtaccga
    13201 ttgctttgat tcgcccatct tctatccaaa tttctgctgg tgtcgtcata ttttttcgtg
    13261 tattgatctg accgttttta atgagtgttt tcattttttc atcctcctat aattacgctt
    13321 ttccatttag cactgcttct aagattgcca ttctgacgaa tactccattg ctcatttgct
    13381 gaacgatccg cgactgtaat ccttccacta atgaatcagc taattctaca tcacggttaa
    13441 ctggtgctgg gtgcataatg attgcatgtt tttgcaactt cttcgcacgc tcaactgtta
    13501 acccatgttc ctgatggtag ccttcttttg agaaactttc ttttccatca tggcgttcgt
    13561 gttgcacccg aagcatcatc atgacatcaa cttgatctag tagttcatcc aatggcatat
    13621 aatgtccgta cacttcgaat tcatcgtcgt accattctct aggacctgag aagaatactt
    13681 gtgcgcctag acgttttaac atctgcatat tggatttagc tacgcgagag tgagtgatat
    13741 cacctacgat ggcaactttc agaccttcaa aatgaccaaa ttcttcataa atggtcatca
    13801 aatcaagcaa gcattgggtt ggatgctgtc cgcttccgtc tcctccattg ataatcgaac
    13861 actggattgt tttactttgt atcagttcgt cataatagtt ctcatcacca tgacggataa
    13921 ccgctacgtc tacgcctaat gctgacatcg tcagtactgt atcgtatagt gtttcccctt
    13981 tttggacaga gcttgtgctt gcttcaaatt caatcacttc tagccctagt tttttctccg
    14041 ctacatcgaa gcttttatgt gtgcgagtac tattttcgaa aaagaggttt gtagcaaagt
    14101 actggcgctt ttgcggagtc caattagcac cttgcttgaa ttcctgccct ctgcggatca
    14161 agcccataac ttcttgatca gtaagtgcct caacggtcaa taaatgcttt aagctgatac
    14221 gttctgattt gatgatcata atgtttcctc cttagttttc ttcgcttcgt gaagtttctg
    14281 gtaagataag atttaaaatg atgccaagta cagttgctaa tgccattgcc gacaatgtaa
    14341 atgtgcctac ttcaaagacg agtccgccaa ttcctactac taagataact gaagcaatca
    14401 acagattttt ctttttatca aaatcgattt tgttctcgat taaaatcttc attccacttg
    14461 cggcaattac tccaaataag ataaaactga ttcctgagat gactggtcca gggatactta
    14521 aaatcaaagc gcttaatttt cctacgaatc ctaaaatgac tgcaaatact gcagctccac
    14581 cgatcacaaa cacgctatgg acacgtgtga tagccagaac accaatgttt tcaccgtaac
    14641 ttgttacagg aggacctccg acaaaggctg ccacgatttg tgctaatcca tcacctgtca
    14701 acgtcttatg aagacccggt tcttcaaaga aattacgttt agttagttta ttcaatacca
    14761 taagatggcc gatatgctct gtcatcgtca caaaagcgat gggtgccatt gttgtgattg
    14821 ctccaagata tagctttggt tcatattgta caaagggaat ctcaaagtta ggaacagcaa
    14881 accaggcagc gtctacgatt ggcttagtat ccacgattcc aaacagcaag gctacgatgt
    14941 atccgctaat aatacctagt aaaatcggaa tcaatccgag aaaacctctt agccacatgt
    15001 tgaagaaaat tgttaatcct aatgtgatca gcgctacagc aatatacttg aaatcatacg
    15061 tgccctgatt atacatagca tttgttgctg catttgccgc aagtcccaac ccgataacca
    15121 tgatgactgg accgacgacg attggaggca agattttatc cagccatgct gaaccgatct
    15181 ttttgatgat cagcgcaaca atcaaataga ctaatccagt tgtgactgct ccttgtgcaa
    15241 tcgctggata accatctgtt ttcatcaaaa gctgcatcgc tgcaatgaaa gcgaagctgc
    15301 ttcctaagta cgcaggtatc tttcctttag tagtaaataa gtacaccaat gtacctagtc
    15361 ctgaactgac tagcgcaata cctggatcga tacctactaa gatggggact aacacggttg
    15421 ctccgaacat cgtgaacaag tgttgtaaac ttaatcctac ccaatgtcct ggggttgggc
    15481 gatcgtggat atctaacacc acgtcatcat tatgaaatcc ttttttctcc gacatgtttc
    15541 tctctcctct aatcttcctc tttcaaaatc atgatgcgat cttgtccatc aagctcttgc
    15601 atctctacta aaatctcttc cgcccgagat gttggaatgt tcttcccaac ataatctgca
    15661 cggattggca attctcgatg cccacgatcg accaggactg ctaatgaaat ttttcttggt
    15721 ctgccaaaat ccattactgc gtccattgct gctcgaatcg ttcgtcctgt atacaaaaca
    15781 tcatcaatca aaataacttc ttttccttct aaggaaactg ggatgtcaga agaatgaagt
    15841 tccggttctt ctggattttc ttttttgtca tctcggtata aagtgatatc cagttctcct
    15901 acaggaatat cgatatcttc tagctgcttc aggcgttcgg caattcttga tgcaatgtag
    15961 attcctcgtg ttttgatacc taccaatacg atatcttgga tactatggtt tctctcgata
    16021 atctcataag taattcgagt caatgctcgc ttcatggtta cctgatctac tacttctttt
    16081 gcttgcattt tcattccccc tacttttttg cataaaaaaa ctcctgccct aagaggacag
    16141 gaggaatgtt tagactgagc gtatactgat acactgatag ctatactatg tcaatgagca
    16201 atctacttat ggcgcaccat acgtatcctt gctcccaccc ttcttagcct cacgggacta
    16261 aacttaaagg aattctatta agttttatgc tttcgttgtt aattactata ccgttatcta
    16321 aattaaaatg caatgttttt tcttaatttt tctaaagttt tttcaaaaac ttctggaaga
    16381 ggtgcttcaa agatcatctt ttcgtttgta gtcgggtgcg taaaacctaa catttgcgca
    16441 tggagaaact gaccattgcc tttcaaagtt ttcttcggtc cgtatactgg atctccagct
    16501 aacggataac cgatatactt catatgcaca cggatctggt gtgttcttcc ggtttctagt
    16561 tttaattcaa ccagagtaaa tccttcgaaa cgttccaata cagtaaaatg tgtgacagcc
    16621 gacttcccat cttctcttat cgcctgcatt ttccggtttt ccttcgaacg gccgattggc
    16681 gcattgatgg ttcctttttc gtgaggaatc tctccatgga ctaaagcaac atatttgcgc
    16741 aaagaggtct tatcttttaa ttgctgagct aatgattcgt gtgcctggtc atttttggca
    16801 accattagca gtccggaagt atctttgtcg attcggtgaa caatacctgg acgaataacg
    16861 ccgttgatcg tagaaagatc cttgatatgg tacatcagcg cattgaccat tgtgccatgc
    16921 gtatgacctg ctgaaggatg aacgaccatt ccttgaggtt tgtttatcac cgctacatct
    16981 tcatcttcgt aaacgatcgt caacgggata ttttctggga ccacatctaa tgtttctggt
    17041 tcggggatca agacagtaat ctcgtctcct tgttttactt tgtaatttgc tttgactggc
    17101 tgtccattga cagaaaccgc tccatttttc agccacagct gaatttgcga acgactgtaa
    17161 tcggtgaata aattagtcaa tactttatcg atcctaccag attcatggtg aatcgtcgtt
    17221 ttaagttctg tcattttttt ctttgatcct tttcatctaa aataatataa attaacatac
    17281 aaatcactcc acatacaagt gtcacatctg ctacgttaaa aatcggaaag ctcataaaat
    17341 ctgtctggaa catatctact acatagccaa gacgaatacg gtcgataaaa ttgccaatcg
    17401 caccagctag aatcaaactc aatccaatca tgaaccagcg attacctttt tcacgatttt
    17461 taatcatcaa tgtgagaatc acaacgactg caatgagtgt cactatagta aagaaccaca
    17521 tcttcccttc tagcatactc catgcggctc cagtgtttcg aatatgattc agtgacaaaa
    17581 tacctggtat aagatttttc gtctctccaa gcgctagatt atcagtgatc caccatttga
    17641 ccaactgatc cactcctact agcaaagcgc tgaatatcca ataaataatt aacaaaaaat
    17701 caatcctttt ctatttgttt ataaatatca cgaggtcgta cgatcccgag cagattacca
    17761 tcgggattcc catctttagt gataagtacg gcttccaaag tcccttgctc acgaaacatc
    17821 gcttcaacct cgtaaatatg tgttttagct ggaacaaaat gataatttgt gtactttccg
    17881 ttttggatga tcaaatccaa cgctcgttta tttgttaaat caaccggacc tttttggctt
    17941 tcttttgcta gccaaaaccc gatattacgt aaagtaatca atgctacaaa ttttccttta
    18001 ttgtataacg gaaattgtga ataccttttt tctgctacta tctttaacag ttcaagtaac
    18061 ggaagatctt gttcaaaacc tgttacacgt tttgcaaatc gaggcagcac ggtttcaggc
    18121 tgaatcagtt cttgttcgat cagctggatt cgcttgactg tccaatcatt tggctctgca
    18181 atgacaaaat cgactgcgat ccgatcatgg acgatcgcat tccttaactg agcaagctgt
    18241 aaaagatcat cttcgtattt tctgatcatt aattgttttc tttgagctag gcgtctgaca
    18301 agttcggtaa atcccatatt tcgtgcattt cccatctcgt ctctcatcca tttttcgatt
    18361 cgattgaaac tgattaaaaa aagatcagag tttgccataa ttttcctcct tgatcaaata
    18421 tgcccggttt tttatataga aaaagaacgc aatcaacaca ataactgcaa aaaaactgaa
    18481 aaataaattt tgtaggaaaa cggcccccaa cccagttgct agaaataaaa acggatagat
    18541 ttgaagaatc aagtaattca ttgtgatcac ataagcaggc tttgcttctt tcactgtata
    18601 aacggggctt tttagccaat aaaaggtgac ctgcatcgta aagggcactt ccagatcaag
    18661 cgttatcttt tgttcatgac tgagaacact gcgtttttca ttgttgattc ttagctgaat
    18721 cgagctaccc ataccgtaaa aaccggtttt tcttataaat gtcgttttca tcataccctc
    18781 ctattatgct ttagtatagc tcaaaataca ataaagaaaa agaatgatcc tagtgtaaac
    18841 aaaattaatt ccctatcgtc taaaaaaaga agctgtagtc aaaatacagc tccttcgatg
    18901 gtagattata atcaagctta aaacaatccc aacacttctc cgtcatttgt cacgtccata
    18961 ttcaatgcag caggtttttt aggcaaacca ggcatcgtca taacatctcc agtcaaggct
    19021 actaaaaatc ctgcccctaa ttttgggatg atttcgcgga tcgtgatggt gaaatcttcc
    19081 ggtgcaccta gcagtgaagg atcatcagaa aatgaatact gtgtttttgc catacaaatc
    19141 ggcagtttgt cccatccatt cttcgtaaac tcttctattt gtttttgcgc ttttttgctg
    19201 aaaacaacac catttcctcc gtaaattttc ttgacgattg tttctgtctt ttcttgtatc
    19261 gtttcttcta ggcggtataa tggcttgtaa ttagcttctt ttctatcaat caatcgtact
    19321 acagcttttg ctaaatcaac gccgccttct gctccatctg cccatacact cgctctcttg
    19381 gcaagaatcc cctgattttc acacaagtgc tccaacagtg tgagttcatt gtctgtatct
    19441 gttacgaatt cattgattgc gacgatcaca ggtagctgat attgttccat attacgtata
    19501 tggcgcttta aatttgcaaa acctactttc aaagcatcaa gattctcatt tttaagttca
    19561 tcttttttca ttccgccatg cattttcaat gcacggacag tggcgacaat caccacagca
    19621 tccggcgctt ttttcaagtt aggtactttg atatctaaaa atttctctcc gccaagatct
    19681 gcaccaaatc ctgcctctgt gacaacgtaa tctgctaatc tcaatgctgt cttggtagct
    19741 aaaatactat tgcagccatg agcgatattg gcaaacggtc ccccgtggac aaaagctggt
    19801 gttccgtaaa ttgtttgtac aagattcggc ttgattgcat ctttcagcag taatgccaga
    19861 gcgccttctg ctttcaagtc tccagcagtc acaggctgac ggtcaaatgt atagccgaca
    19921 acgatccttg caagacgagc ctttaaatct tcaaggtctg ccgcaagaca caagatagcc
    19981 atgatttcgc tggcaactgt gatatcaaac ccatcttctc ttggaacacc ttggattggc
    20041 ccacccaagc caacaattac tttacgcagt tcacgatcat tgagatcgac tacccgtttc
    20101 caaatcactc ggcgggcatc gatgttcaat tcatttcctt gatgaatatg attatctaaa
    20161 agagcagata atgcattatt agctgttgtg atagcatgca tgtcaccagt aaaatgcaag
    20221 ttgatatctt ccataggcaa tacctgtgca tatcctccgc ctgcagcacc acctttgatt
    20281 cccatcacag gaccaagtga gggttctcgc aatgcaataa cagatttttt attgatttta
    20341 ttgagcgcgt ctcctaaccc tacagtgatc gttgactttc cttcgccagc tggtgttgga
    20401 ttgatggaag taactaagat caaatgcccc tcagcgttat cctttgatcg attgattcca
    20461 gaaaaattga ttttcgcctt atatttccca tacagttcca aatcgtcttc cttaagatct
    20521 aatttactag ccacttcaac aatcggttct agctctgttt cttgtgaaat ttgcagatca
    20581 ttcttcattt gattacccct tttcacgaac tttattcaac aaaatatctt ctttgttaag
    20641 atatgccaat tatacctttt tttattcaga aaaaaaacat aaaattacag gtttttaatt
    20701 tatttgacgt acttataaat actctttata atgaaggcta tgatcagact ttagaaaggt
    20761 cgtgagtgct ttgaccacag gaattgtaaa atggtttgac aacaaaaaag gatacggctt
    20821 tatcagttat gatgacacag aagaaatttt tgtacatttt actgcgattg aagaagaggg
    20881 attcaaaact ttggaagaaa atcaagtggt cgaatttgag atcatcgaag ggaatcgagg
    20941 aacacaagct gcccatgtca agaaaggcaa cgttcagact accgatacta gtatgcatga
    21001 atagataaac aaatagagtg agacgctaaa cgggatgaac cgtacgtctc actcttttct
    21061 tttcctgtaa aaattcgttt ttttaggttc tgatttttaa aattagcttt ttcttttttt
    21121 cgtataagga taaggaattg attctgattt gggtccgttt ttttcaaaat gatcaaaaag
    21181 gactacttga tctttttttc gcatcatgaa aacagatggg gctttctcat cttgcaacat
    21241 catttgcacc ccagtattag ttggcgtcaa agatcgaatc tgtccgacag atatttctcg
    21301 gtctttccaa aaagcagcat aacgtataat cacagagttt gattttaaaa taaaagaacg
    21361 ccgcaaacct agaaatagaa aaacaagaaa aatacctaaa acaaaattgc ttttccaata
    21421 aggacctgtg ttttctaaag aaagaatcag actaaaaaac agaatgatca aggtcaatga
    21481 ccaatagatg atcgtatgtg ccagttcagg ctgccatcga atattttttt tcattctcta
    21541 acctctcacc gattcagtaa tgatataatc ttaccataac attagtttga acaaaaagga
    21601 gaatctcttt ttatgttaaa agtatacatt gatgcctcta caaaaggcaa ccctggtcct
    21661 agtggaggtg gaatcttgat tgtctatcaa ggtaaacaag aacagctatc tatcccgctt
    21721 tctataggga caaaccatca agcagagttc gaagtctttt taaaaacttt agaatttcta
    21781 aagaaaaacg acttacagaa tgaaacgatt ttctgttttt cagacagcaa aacactagtt
    21841 tctacggtcg acaaaaacgc aacgaagaac gagctcttcc ttccctacct tcaaagaatc
    21901 caagaacttc tatccgaatt ttctttattg atcctgcaat ggttgcccga aaacaaaaat
    21961 aaaggagcag ataatcttgc acgtcaggct ctccataaac aattaaaaga aaaaaagact
    22021 ctttaaatta aaaactttaa ggagtctttt tatagtttct catttaatat aaaagataat
    22081 tgtgatcaaa cgtaatttcc aattggtaat ctccgatttt ttcttctatt tgactacgta
    22141 agattctttc tagttctgta tcaacaaact ggaatttctc agggaccact acatcaaatt
    22201 gcagcgtttt tccttgatga attactctaa aatcatgaat attaagccct gtacctgttt
    22261 caagaagaat ttgctttaac tgccgcaaga tattatagta tttttcgtta tcaacaggca
    22321 ttggatccaa gtgacagaca agttccacat ccaaagactt tttaaagtct ttttctatca
    22381 gatcaataat cttatgagcc acattcaaat tcattgattc atctacttcg atgtggactg
    22441 atgcaaagcg tttattgggt ccatagttat gcaccaataa atcatgatag ccaagtatat
    22501 catcgcaagc atttaaatgc tcttccattt cttcaatctc tgctggcgtt gggcgacttc
    22561 ctaatagttc gtatacaaaa tttcgaagca tcgtcaatcc actataaagg atatataatg
    22621 ctaaagcaaa acctatatat ccatcaatac gccatccagt tacccattcg attgctgctg
    22681 aaagcaatac agccagtgta gtaaagacat cattataact atctgttgct gtagctctca
    22741 atgtttcaga atcaatggat tgcgcaataa cctgatacat tttgccttgt gcaaatttca
    22801 aaaagatgga aatgattagg acaaaaaaga cgatgggtgt taaagagaca ttttctggat
    22861 ggatgatttt ttcagcagaa gactctaaaa attgaaatcc tacataagta atgatgatcg
    22921 aaacaaataa cccactgata tattcgaagc gttcgtgtcc ataaggatgt tcctgatctg
    22981 ctggctttgc agcaatttta aatccgatca aagtcaatat ggatgaagca gtatctgata
    23041 gactgttcac tgcatcagcc ataatggaga cacttcctga aaaaagcccg atcattagct
    23101 tagagacaaa caagatcaga ttcgtaacca atcctaagat acccgctagt actccttttt
    23161 ttgtccgctg ttgcggtatt tgtttctttt tttcttcttg tttcttagcc aagtttttta
    23221 ccccttctag tttgcttgtt gctcaggtaa aaagatggag aggacgattg ttttcctctc
    23281 ctctcttcct ttttctatct atcgtgcgtc ctattactat taaaagatgg tcattattct
    23341 ggtttcaacg gtgttgctgc aaataacgct tttgctagta atggtgttat gattcccgca
    23401 cctattgctt ctggtatccc attgattgct gcaacccctg ctaaggtttt aaataaaaga
    23461 gcagagtcta caccataggc atctgccgtt gcacctgtat aaaataatcc catgaatcct
    23521 aacactaaga ctgtattgac caatgaaccc agtacccctg caaaggctga gctgatcgtt
    23581 attgatttat ttttttgata aatccagtgg aaaaccaagc ctgctactaa gccaacaagt
    23641 actctgggaa ctaccgagat aatcggattc gtgaacacta atgtatcaaa tggcgttgtt
    23701 ggcatggcat aggcacgaac aattgtagcg attccccaaa acaagccaat caccatgcca
    23761 tcttttgggc ctaatactac tgcagcaata attactgtga tatggataat tgttaaacta
    23821 atgaatccta atggaataaa ccccagccaa ggaaccatcg cttgtacgat gatgattgct
    23881 aacaagatcg cacgtaagac tagtcgaaag gtcttatttc tactattcat tttttcaccc
    23941 ctttttattt atactaatcg taaaaatttc tgtcactttc gtcaactaaa gaccatccga
    24001 atccgaccat ttgattagat gcgccatcca attgaaaaaa gtatgagggc aagacttgtt
    24061 tgtcttcgcc cccataatca tgtttcgttc aatgtttgaa cttttgtttt tctgtcaaac
    24121 gtaaacgccc tattgttgcg caacccattc tttcgcagct ttaagtgcat ctggaatacc
    24181 agcaggattt ttcccgccag cttgtgccat gtctggacgt ccaccaccgc caccgcctac
    24241 tttcggtgcg attgctttaa tcaagtcgcc agcttttagt ccagcttcat ttgattcttt
    24301 cgtcattgcc gctagcagac tgacttttcc ttcttgttcg tttgctaaaa caagaatatc
    24361 tgaaatattt ttttgtttcc attggtcagc taattgacgc agctgattca tatctttcac
    24421 ttttacttgt gctgcaatga ttgtttttcc attgatcgtt tctggatctt tgaatacatc
    24481 accagcttgt tgattcgcta acttgctagc taattgttca ttttcctttt gtagctctct
    24541 tacttgctgt tgcaattgtt ccgcttttga aacaacttct ttcaattgag gtgatttaac
    24601 aattgttgct acttgtttta gttgtttttc ttcttcttca agtagttcgt acgcttcttt
    24661 acttgttaca gcctcgattc gtcgcacgcc tgcaccaatt cctgattcag aaacgatttt
    24721 gaagattccg atgttttctg tatttgctac atgtgtgcct ccgcacagtt cgattgacca
    24781 gccgccaata tttactactc gaacgtcatg tccgtatttt tcaccaaaca aagccattgc
    24841 acccatgttt ttggctgtat cgatatctgt ttcaattgtt tcaactggga tagcttccca
    24901 gattttttcg ttgacgattc tttccatttc agctaattca tctgaagtga tttgaccaaa
    24961 gtgggtaaag tcgaatcgta aatgtccagg agcgactaaa gaaccagctt gatttgcatg
    25021 ctcgccaagt acttctttca atgccttgtg cagtagatgg gttgctgtat ggtttttgat
    25081 gatccgattg cgcatcgatt gatcgatcaa tagatgatag gtttgtcctt cactcattgg
    25141 tgcttttact tctacggtgt gcataaattg accattaggc gctttttgaa catctgtaac
    25201 aactgctacg atttcgccta cttcattcat gatccatcct tgatccgcta cttgcccacc
    25261 catttctgca tagaaaggtg tttgatcaaa gatcatttga gcttcacctt ctgcgacttc
    25321 attcaaaaga gactcacctt taacgatgac caataattga ctatctgatt cttgttctgt
    25381 gtatccaatg aatttacttt ctactttgat atctgtcaat aaagcagatt gtacccccat
    25441 tgatttttca gtactgcggg cagagcgagc acgttcgcgt tgtgcatcca tttctttttc
    25501 aaaaccagca tgatcaactt tcagtccttc atcttctgcc acctcttccg ttaattctac
    25561 cgggaagcca tatgtgtcgt atagtttgaa gatgtctttt cctgctagag tcgtcccgtt
    25621 ttcgtttttt acttcttgga tcacttgatt taagatttcc aaaccttcat tgattgtttc
    25681 attgaaacgt tcttcttctg tacggataac tttttcaata aattcttttt gttgaagtac
    25741 ttcaggataa taacttacca tgatttcccc aacaacaggg actaaacgat ataagaatgc
    25801 ttgttcaata cctaattttt tcccatgcat gacagcacga cgaagcaaac ggcgtaagac
    25861 ataccctctc ccttcattcg atggcaatgc accgtcgcca atagcaaatg aaagggcgcg
    25921 aatatgatct gcgattactt tgtaagaaat atctgttact gggttttcac catattttac
    25981 ttgtttgctt agcttttcta cggcgtggat aataggcata aacaagtctg tctcaaagtt
    26041 cgttgacgca tcttgaacga ttgagaccat gcgttccaat cccatccccg tatcaatgtt
    26101 tttatgagga agtggttcaa atgtgttatc aggcttatgg ttgaattctg aaaatactaa
    26161 gttccagatt tctaaataac gttcattttc tcctcctgga tagttttcag gatcgtcttc
    26221 tgctaaatcg ttataagctt ctccacggtc atagaaaatt tccgtatccg gaccacatgg
    26281 gcctgcaccg atatcccaga agttgtcttc tacatcaata atgtgatcta gtggcaggcc
    26341 aacttcttca tgccagatgc gttttgcttc tgtatctttt ggataaactg ttacataaag
    26401 tttttctgga tcgaatgcca tccattttgg atcagtcaaa aattcccatg cccagtggat
    26461 ggcttcattt ttgaaatagt caccaatcga aaaattaccc agcatctcaa acatcgtatg
    26521 gtgccgtgct gttttaccga cattttcgat atcatttgtt cgaatagatt tttgggcatt
    26581 tgtgattctt ggattttctg gcacaactga accatcaaaa tattttttca atgttgcaac
    26641 accagagttg atccacaata aggttggatc gttcacgggg atcaaagacg cactaggttc
    26701 aatcgtatgt cctttagatt ggaagaaatc aagaaacatt tgtcgaactt gtgcactact
    26761 taattgtttc atgtcattac ctgctttcta taaattaaat acaaaaaaac accatcacag
    26821 ccaaggacga aaactcgcgg taccaccttg attgcaatga tgtgtaatca ttacctctta
    26881 aactcgataa cgctgagctg cgtcggtatt tctaccaaaa tagaaaaagg gagcaatttg
    26941 attagtgact attctttttt cagccaagaa agaattttct gtgagtctta aaaaacaaat
    27001 catatccttt tcgtacttaa ttagtatacg cattctattg atcactgtca atatctcaat
    27061 ttttattttc atttcctttt ggtcatactc cacgattttt ggtacgataa gaataaagga
    27121 atcaatacat ctctgctatt catgacaagg aggaatatga tgaaaaaaat agttggagcg
    27181 gatgaatgga tacgcgcagc tagctgcttt ttgagatatc aagtttttgt attagaacaa
    27241 gggattcctg cagaactaga attcgacgga aaagatatcc cgcaacaaac ctattatcta
    27301 tttcttgatc aaaaaagacc agtagctact ttgcgttatg aaaagaaaac acctacttgc
    27361 ttcaagccgg aacgattttg cgtagcaaaa gaataccgag gaaaagggtt aggcggtcag
    27421 ttgcttgaag ctgctgaaaa acgggcggtt tcagaaggtt gtcagactag ttatgtagta
    27481 gctgaaatga cggctgtaga tttttatgaa aaacaagggt atcatacttg cacagaacct
    27541 tttattgaag atgaagtact ttgtatcgga atgaaaaaaa gtctagctta aaaacaagag
    27601 attgtgacac gccttttgtc acaacctctt gttttttatt tatgtgaatt tttcttattt
    27661 ttacgagcag tacggctttg ctgtctgcgt tcgattttgc gttctttttt atttttttct
    27721 gcaattgccc aatcgatttt tttcttataa ccaggcttga tctttttctt tttcttcttc
    27781 acaagaccaa tcagcgtggg atctaataca tcttttgatt tttctcgttt ggcacgtcta
    27841 ttacgatcgt atgttttgac gatttccccg tttttgattt cttttggttc aaatgagacg
    27901 cccaattttt ctatcgcatc aatggcttgc tcatcatttg gcgaatataa cgtaatggcc
    27961 gttcctttta agccattacg tccagtacgt ccgacacgat ggataaagaa gtctagatct
    28021 tctggaattt ctgcattaat aacatgagag acaccttcga tatcgatccc tctagcagct
    28081 aaatcagtcg ctacaacata ttgatactcc agattctgta cttgtcgcat cactcgtttt
    28141 ctctctcttg gggtgatgtc tccatgaatc tttgctactt tcaagccttg gtttttcaag
    28201 taatcggcaa tttcatccac atgctgtttt gtattggcaa atacgattgc taaataagga
    28261 tgaccaattg tcagcagttg ataaatcatt tgattctcat ctttaccttt tgttgaaatc
    28321 agccaatttt caatgtcttc agaaataact gcttttggtt tgatttcttc aatgattgga
    28381 ttttccatgt attttcgtaa gaatggacga agtttttctg gaatagtggc agaaaaaact
    28441 aaaaactgca gcttttctgg taatcgactt gcaatttggt ctacttcatt taaaaaaccc
    28501 atatccaatg tcatatccgc ttcatcgaca acaaatgcaa atgcggtgtg aatcttcagc
    28561 gcttgttcat tcatcatgtc taatattcta ccaggcgtgc ctactacaac ctgtggctgt
    28621 tggtgatgca gacgatttaa ttgacgctgt ttgtctgtac cgccgacaaa attcgagaca
    28681 cggatctccg gtgtagaaaa tttagcgatt tgtgtagctg cttcatagat ctgtgcagct
    28741 agttccctac ttggagctgt aataacaact tgtacttcct ctttttctgc attgattttt
    28801 tcaaacaaag gcaacaaaaa cgtatgtgtt tttcctgtac cagtttgaga ttgcccaatg
    28861 atattttttc cttttgcaat taaaggaatc aaacgttcct ggacctctgt gggctgtttg
    28921 aagccctttg cggttaacgc ttcattgata aacggtttga agcggaatat atcaaaatta
    28981 ttcattcgtg cacctcttct ctttaaatta tcacgacttt ggcattataa cacagacaaa
    29041 gcgtttttgc tcagctaatt tcgagaatca tcatcctttg tttggccaat cgtgctaaca
    29101 gtatatgtgt gactagcttt ttcataaaac agaatccgtt tttttctcaa aaatgatagc
    29161 aagatattta aaataaaaat accttgtagt aacaagacac cgagagaaat gaatactgca
    29221 ctcatctgca acaccgtatt cgttgtcgaa ttcatgattt gctgaagcaa ctgccccaac
    29281 cagcttaaac cataaaaaag aaagtacaga tacccgtagc ggatcatcaa tgcttttaaa
    29341 gaaattcgtt cgcggtcttc ttccaccaaa cggatacgca caattttttt gccaagtgtc
    29401 catccattgg ttataaacgg tacaatcata aagtataccc ctacttctaa taaaagccac
    29461 cagatatgag aagtaactgc ccctgaatcg aacgcaattt taaagaaaat cgccgctacc
    29521 aaattaataa gagataaaaa tgtccagtcg atcaaataag cgaccaagcg tcgagtcaat
    29581 gagacagtct ttcctttttc ataagaaagt tcatccattc gtcttcttgt aggaagcata
    29641 aatgtaaata acggcgtaac gacaaaacca atgattccac ccaatgtatt tgtcactaaa
    29701 tcattcacat caaataagcg gtatggtctt gggtagataa aataaagtcc acttagctgc
    29761 gtcaattcaa aaaatagaga aaggcagaaa ctagcaatca tcgttttcat aaaagaaagc
    29821 cggaaataat atcttaaata aatgccaaac ggtatgagta ataaaacatt aaaagctggt
    29881 tccaaaaata cactctgctt cattgccggc aggtaggtac taggttcaga caagaccaat
    29941 accgtgttgt ctctgaaatg ttgccatgaa gcaaataaat gcagctccat ctttggccct
    30001 gtcatttggg caaccgtctc ctttgccgga agtggtaaga tcaccaaaaa atacgcacac
    30061 aataaataaa aaacgaaaga atacaaaata actgcccttg ttactagaaa tgttccatac
    30121 tttcgatatt cataaataaa aaaaacagat gagatcgcta aggctaaaaa tggaaaaaca
    30181 atcagcgcaa aacgaatcgg ttcgatataa cttgccatat gactcctcct tgattctttg
    30241 tatctctctt atcttagcag tcctttgctg tttcaagcaa gtaacgaggc tattatttct
    30301 catttctttc aaagtaaagt aagataaaca caaagggggt gtcgagatgc tgaatatgta
    30361 ctttgttttt ggcgtaccta tttttttact gttcctttat gctacgatcg cttatgtaag
    30421 aaaaagaact acaattcatt atttaggatt tattctcctg attatttcgg gtttcatgct
    30481 agtcttcaat cttcagactt ggcagcaagc acttcttgaa atggataaaa tgactccaca
    30541 tgctttgtct aaagtgcttg gctaccctgt ctatctgatt tggcttccca ttttcatttc
    30601 tggttgcttg gttttattaa atatttatcg cggcgtacgc cgaatagttc agttacgcaa
    30661 atcaaagtaa aagacagaaa tcggttgagc ccgatttctg tcttttactt tgctatttca
    30721 tcgtagacaa aacgacattt acgtgatcaa aattaacgag tacttttgac atttcttcca
    30781 cgtactcctc atttaaataa aatattttgt ttggcagaga agtgcagttc taataaaatt
    30841 cgaatgtttt agctatctac gttttaaata gagataaatc gggataccag caagtgtcaa
    30901 tactatcccc atcgaagcta aaaaggtctg agtgataagc gtgcttgata cgataaaagt
    30961 ccctccaatg attgctacta gtggaataaa cggatacatt ggaactttgt atggtcgaaa
    31021 caaatcaggt tcttttttac gaagaagaat gacaccaaca aagaccatcg tataaaaaat
    31081 ccaaatgaca aagatcagca tatccgttag tgtatcaaaa ccaccgatca tcatcatgcc
    31141 aatagcgatg actagctcta agatacctgc ggctacagga actttagttt tatcatgaag
    31201 tttagcaaag agcttgctaa aaggcaggtt gttttctttt gccataacat aagggagacg
    31261 cattccagta agggtatagc cattgatggt tccataaaca gaaatcaaga taccaactgt
    31321 gaccagtctt ccaccgaagc cgccaaaaat catttttgca acgtcacttg ccgcattgct
    31381 gtttcctgcg actccgtcga tagatgcggt tcttaagaac accgcattta ctaataaata
    31441 aacgatcatg attccgatga ttcctaaaga aattgctttt ggcaaatctt tcgccggctt
    31501 tttcaattct cccgaaatat ttcctacgtg tatccaaccg tcgtatgcga acatcgttgc
    31561 tagcaagccc gctcccaagg ctgagaaaaa tgaaagattt tctcctgctt ggatcggaaa
    31621 cagttggaag tctactcctt cttgtcggaa caaaccgaaa atgacgatca caaacaaagg
    31681 aataagcttg cagacaagcg taatcgactg aaaagcccct ccagctttag aacctaaaaa
    31741 attgatcaac aggatcgata cagcagctgt aacagctacg ggaacaatca ttgactggga
    31801 aagaccaaat agattgacga actgtgtacc gaaaatgatc gacaaggctg ctacatttgc
    31861 tggaaaataa atcacgactt gcgcccagcc caataaaaaa gctgctgtat ttccgtaaat
    31921 ccgttcgata tatttaatca tccctcctgt ttctggaata gcagctgcca gttcagctcc
    31981 tgttagtcct gcacagacag aaatcatacc accgagaaac caagaaaaca tatgcaaact
    32041 ggcggatcct gtaacttctg ctacgcttgc ggctttaaaa aatacccctg caccgatcac
    32101 tgtgcccata acagtcgata aagcagtaaa aaatcccatc gtacgtttta attcattttc
    32161 tatttttact tcttttactg gcgtggcttg atattcttcc atcccttgtc ccctttcata
    32221 ccatagccaa tcccaaaagt ataaaaaact ttttggatgt ggttcttgtt ttataccgtc
    32281 tctaccaatt tttctttcag tttttccaac atatcctttg tcatcacatc taagtcgtat
    32341 ttcggcgaaa agccccattc ctcttgcgca caagaaacat ctagtgaatt tggccaagat
    32401 tctgctattg actgacgtac aggatccaca tcataatcca tttcaaaatc tggtatgatt
    32461 ttttgaatag atgctttgat ctcttccggg tcaaaagaca tcgccgatat attgaaggca
    32521 tttcgatgaa ccaatcgatc aggatctgca ttcatgagtt ttataatggc atcgatcgca
    32581 tctggcatat acatcatatc cattgatgta ccttgatcaa tgaaactagt gtactttcct
    32641 tctttgattg ctgaataata aatatcgact gcgtagtctg tcgtaccgcc tcctggcaag
    32701 gttgcataag aaatcaatcc agggaaacgg acaccacgag tatctacgcc atatttcaca
    32761 taataataat cacatagtag ttctccagct accttcgtta ccccatacat ggttgtagga
    32821 cgctgaagag tatcttgtgg ggtatgatct tttggagtat ttggaccaaa cgcgccgatt
    32881 gaacttggcg taaaaaattt cagctggaat tctctagcga cttccaatgc attgaccagc
    32941 ccagtcacgt tcaaattcca ggctaattgt ggttttgctt ctgcaacagc tgacaaaaga
    33001 gcagccaaat gaatcaatgt gtccacttga tattgttctg ctatgctgcg cattttttcg
    33061 taatccatta catctaggat ctcaaagata tcgtttttct caatgacttc aggcatgcgt
    33121 atatctgtcg caatgacatt ttcactgcct agttcttgac gtagccgtgt gatcaactct
    33181 gaaccaattt gtcctaaaca tcctgtcacc aatacttttt tcatgatgat cctccctgat
    33241 cttttttact actatcttca gatgattaac aatatatgcg tgaacatgtt ctctaatttt
    33301 aaatagacga aaaaactaaa tttagttaaa taatttccat ttcttttcct attttttgat
    33361 aaactgctac tgcttcatca agcatttccc tcgtatgttc cgcagtcggc atatttctga
    33421 tcctgcctgt cccaagaggc acagttggat aaacgattgg tttagcataa atcccatgtt
    33481 cgatcagctt cttagagaaa gtctgagtca ctttttcgtc tcccaaaatg actggagtaa
    33541 taggtgtttc agacataccg atgttatagc ctactttttt caattcttct ttaaaataat
    33601 tagcattttc ccaaactttt tcgacaagtt ccggatgttc ttgcatcaaa gtaatcgaag
    33661 ccaatgcagc tgcagctgca cctggagtta gcgaagtaga aaataggaat ggccgacttc
    33721 tagctttcaa ccagtcgatt agtgttttcg atccagctac ataaccccca acaacaccta
    33781 tagctttcga taacgtgccc atttgcatat cgattttgtc gcttaatcca aaatgcttga
    33841 cggttcctgc accttttcca gttacgcctg agccgtgcgc atcatcgacg taggtgatca
    33901 gtccatattt ttcaacaatc ggaataattt ccggcaatcg tgcaatgtct ccatccatgg
    33961 agaaaacacc atctgtgata tacatgattt ttttatattt cttactttct atcgcttcct
    34021 ttgctttttt ctcaaggtct ttcatatctt gatgtttaat tcggatgatt tttgctccgg
    34081 ataagcggca accgtcaata atagatgcat ggtttaattc atccgataag atagcatctt
    34141 cttttgtcat tactgcagag atagcgccca tattgcagtt gaatccagat tgaaaggcga
    34201 ttgctgcttc tgtccctttg aattctgcga ttttttcttc taattgctga tggattttca
    34261 gcgaaccatt gatcgttcgg actgctcctg ctcctacacc ataagtttcg gttgcttcaa
    34321 tacatgcttt tttcaattct tcgcgattgg caaatccaag ataattgttg gatgctagat
    34381 tgatcatctt ttttccgtct acgatgatac aagcaccatt ttcactttct agtatgtcga
    34441 tcgtattgta taaccccttt tctttcagtt gatccaattc tttctctaaa tacattgtta
    34501 gttctttgga agacattgtc tccacctcca tattcatctg tcttgcagaa cataccaaac
    34561 atatatcgtg tcattcatct acaaagcaag tatgctatat ttttgataac gcttacactg
    34621 attatgagaa ttatttaacc acatttttta tttacagtat ctttttactt tcaaatgact
    34681 tatatagtat gaacaattac cttttagata atgatctatt ttactctacc tgggcagata
    34741 aatataacac aaccattgat agaagccctt tcgttaaaat caattgtatt ctgaatattt
    34801 aatttattta ttgcatagac caataaaaat acataaaatt tccatcttcg tttatcagca
    34861 atttttaatt ttactctctg aatatttctt aaaagtttta cttgttgaat tcgaaaaaag
    34921 gactgtgaca aaagtcttgt cacagtccta ttctt
//
LOCUS       DAFLVO010000024        34809 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.024, whole genome shotgun sequence.
ACCESSION   DAFLVO010000024 DAFLVO010000000
VERSION     DAFLVO010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.024"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(460..2352)
                     /locus_tag="L1U99_001216"
     CDS             complement(460..2352)
                     /locus_tag="L1U99_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1211767.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2349..4076)
                     /locus_tag="L1U99_001217"
     CDS             complement(2349..4076)
                     /locus_tag="L1U99_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1211768.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(4092..4742)
                     /locus_tag="L1U99_001218"
     CDS             complement(4092..4742)
                     /locus_tag="L1U99_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBN1211769.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4946..5242
                     /locus_tag="L1U99_001219"
     CDS             4946..5242
                     /locus_tag="L1U99_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBN1211770.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5434..6054
                     /locus_tag="L1U99_001220"
     CDS             5434..6054
                     /locus_tag="L1U99_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HBN1211771.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(6146..7312)
                     /locus_tag="L1U99_001221"
     CDS             complement(6146..7312)
                     /locus_tag="L1U99_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBN1211772.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7324..7677)
                     /locus_tag="L1U99_001222"
     CDS             complement(7324..7677)
                     /locus_tag="L1U99_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBN1211773.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7805..8827
                     /locus_tag="L1U99_001223"
     CDS             7805..8827
                     /locus_tag="L1U99_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HBN1211774.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            8846..9007
                     /locus_tag="L1U99_001224"
     CDS             8846..9007
                     /locus_tag="L1U99_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211775.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(9266..9700)
                     /locus_tag="L1U99_001225"
     CDS             complement(9266..9700)
                     /locus_tag="L1U99_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211776.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9810..11669)
                     /locus_tag="L1U99_001226"
     CDS             complement(9810..11669)
                     /locus_tag="L1U99_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBN1211777.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(11787..12947)
                     /locus_tag="L1U99_001227"
     CDS             complement(11787..12947)
                     /locus_tag="L1U99_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBN1211778.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(13254..14678)
                     /gene="araA"
                     /locus_tag="L1U99_001228"
     CDS             complement(13254..14678)
                     /gene="araA"
                     /locus_tag="L1U99_001228"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HBN1211779.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14694..15392)
                     /locus_tag="L1U99_001229"
     CDS             complement(14694..15392)
                     /locus_tag="L1U99_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBN1211780.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15349..17010)
                     /locus_tag="L1U99_001230"
     CDS             complement(15349..17010)
                     /locus_tag="L1U99_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HBN1211781.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            17228..18628
                     /locus_tag="L1U99_001231"
     CDS             17228..18628
                     /locus_tag="L1U99_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HBN1211782.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18880..19959)
                     /locus_tag="L1U99_001232"
     CDS             complement(18880..19959)
                     /locus_tag="L1U99_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1211783.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(20045..21004)
                     /locus_tag="L1U99_001233"
     CDS             complement(20045..21004)
                     /locus_tag="L1U99_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBN1211784.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSKKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(21016..22527)
                     /locus_tag="L1U99_001234"
     CDS             complement(21016..22527)
                     /locus_tag="L1U99_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBN1211785.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22549..23112)
                     /locus_tag="L1U99_001235"
     CDS             complement(22549..23112)
                     /locus_tag="L1U99_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBN1211786.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(23118..23981)
                     /locus_tag="L1U99_001236"
     CDS             complement(23118..23981)
                     /locus_tag="L1U99_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1211787.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23995..24891)
                     /locus_tag="L1U99_001237"
     CDS             complement(23995..24891)
                     /locus_tag="L1U99_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1211788.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(25066..26355)
                     /locus_tag="L1U99_001238"
     CDS             complement(25066..26355)
                     /locus_tag="L1U99_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1211789.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26327..27844)
                     /locus_tag="L1U99_001239"
     CDS             complement(26327..27844)
                     /locus_tag="L1U99_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBN1211790.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            28042..28932
                     /locus_tag="L1U99_001240"
     CDS             28042..28932
                     /locus_tag="L1U99_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HBN1211791.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(29005..29829)
                     /gene="nadE"
                     /locus_tag="L1U99_001241"
     CDS             complement(29005..29829)
                     /gene="nadE"
                     /locus_tag="L1U99_001241"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HBN1211792.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(29841..31313)
                     /locus_tag="L1U99_001242"
     CDS             complement(29841..31313)
                     /locus_tag="L1U99_001242"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBN1211793.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(31950..32312)
                     /locus_tag="L1U99_001243"
     CDS             complement(31950..32312)
                     /locus_tag="L1U99_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBN1211794.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            32535..33287
                     /locus_tag="L1U99_001244"
     CDS             32535..33287
                     /locus_tag="L1U99_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBN1211795.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(33427..34350)
                     /locus_tag="L1U99_001245"
     CDS             complement(33427..34350)
                     /locus_tag="L1U99_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1211796.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(34365..34637)
                     /locus_tag="L1U99_001246"
     CDS             complement(34365..34637)
                     /locus_tag="L1U99_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211797.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        10276 a         7233 c         6011 g        11289 t
ORIGIN      
        1 tgcaagcttt tgaacaccgt ttaaggaaga ggttgtgaaa aagtcgctta gtttcgagta
       61 gtaagaaaaa ttttgtgaaa atggctttct acatttttgc ataaatttgg cttaataccg
      121 agaaactggc ttttgaacac cgtttaccaa gaggttgtga gcctgccgtt taactccgag
      181 tcacaaggag caatttcaaa aaacagcttc tcaggtttgt tgactattgt gacttgtgac
      241 cgaggagttg gcaggagaac accgtttaag gaagaggttg taaaatcagc ggtttgacct
      301 gagtattaga gatacaaaac ggaaaaatag cttctcatat tttgccgttt tttgagctaa
      361 taccgaagga cagctgattg aacaccgttt attcggaaaa agggactgtg acacgacttt
      421 tgtcacagcc cctaaaaaaa ataataaatt tgtactattc tatgaagctt cttcttcaga
      481 aaactgactg ttataaagat ctgcatagaa tccgtctttt tccatcaatg tatcgtggtt
      541 tcctgtttct acgatcgaac catgattcat cacaataatg ttgtctgcat cgcgtattgt
      601 agacaagcgg tgagcaacaa cgaaacttgt ccggttttcc aataggcggt tcatcgcttt
      661 ttgaatcagt atttctgttc gtgtatctac actagatgtt gcttcatcaa ggatcaggac
      721 atctggattt gctaagaatg cccgcgcaat tgtgattagc tgacgctgcc cttgcgaaat
      781 attgcttgca tcctcgttta atacagtgtt atatccttct ggcaatttac gaacaaaatc
      841 gtctacgtga gcagctttag cagcctcaat gatttgttcg tctgttgcat cgtcgttccc
      901 atatttgata ttgtcataga tacttcctgt aaacagccaa gtatcttgca gtaccattga
      961 aaactgtgcg cgcaattcat cacgtgaaag atcacgggta tctacaccat cgtaacgaat
     1021 actacctcca gaaacatcgt agaaccgttc aagaaggttg atcagtgtcg tcttccctgc
     1081 accagtcgga cctacaatag cgaccatctc accaggtttg acatccaagt taaaatcagt
     1141 cattagcaag ttatctggtg tgtagccgaa ttgaacattt tcaaaacgaa ctttgtatgg
     1201 tgtatctttt tcttctggaa ggccagattt ttcattggac atctcttctt catccaacac
     1261 ttcaaatacc cgttcggctg aagcaactgt tgattggata gtgttcatca aacttgcaag
     1321 ttgagtgatt ggttgagaga actgtgttgt atattgcaag aacgcttgaa catcccctaa
     1381 tgtcatgttc ccatttgcaa cttttactcc gcctagtaca gcgacgaaca catagcctag
     1441 atttttaacg aaattcatca acggcatgat gattgccgaa ataaattgag ctttccaacc
     1501 agcggcatac agattctgat tttctttttc aaatacttcc tggtcttttt cagtatgatt
     1561 gaatgtttta acaatggtat gaccaccata tgtttcttct acttggttat tcaataaacc
     1621 taaacttttt tgctgatctg cgaaaaacac ttgtgatttc ggcgctacga tcatcacgat
     1681 gatcaagctt aaagggatca tcaataacgc gactaacgtc aattgccagc tgattgaaag
     1741 catcatcacg atgaccccaa tcaatgtgac tgcactagtt acaaattgag tcaaattttg
     1801 ctgcagcgtg cttgcgatgt tatccatatc attgattgct cgagacatga tatccccatt
     1861 tgtatgtgta tcataatagg aaatcggtac acgattcatt ttggcttcca aatcatgacg
     1921 taattcataa actgttcgtt gggaaacacg tgtcataata aattgctgta aaaagttgaa
     1981 tacagcagaa atcaaataca tcacgattac tgtcgcaatg atctgcgcga ttttatcaaa
     2041 gtctatcgga aattttgtta cttgttggcc ttgttgcatc tgttgagcgc cagccattac
     2101 acctttgaat atttctgtgg ttgctttccc caagaccttt ggtgtttgga tttggaagat
     2161 cacggctgct attgctagta caaatacagc gatgatcgca accatacgtt tagacatata
     2221 gccaaacaat cggcgtaccg ttccccagaa atttttaggc ttttcacctt ttacaccgag
     2281 atttctgcca ggtccaccat gtcctggacc gcctgctggt ccatgagagg gacgtgtgtt
     2341 tgttttactc atgctaagtc ctcctctctt agttgtgaat gaacgatttc ttgataagtt
     2401 tcgtttgttg ctaatagttc ttcatgtgtt cctttgccaa ccagttttcc ttcatctagc
     2461 acaaggatca tatctgcatc cattactgta cttactcgtt gagcaactaa aacggtgata
     2521 ctttctttca tattcgtttt caatgcttgg cgaagattgg catccgtttt gaaatccaac
     2581 gctgagaagg aatcatcaaa cacatagata tctgctgttt tgactaatgc ccgtgcaatt
     2641 gccagacgct gtctttgtcc accagagaag tttcctcctc cttgttccac atggctatct
     2701 aagccatctt ccatctctga aacaaaatct ttagcttgtg cgatttctaa tgctttccaa
     2761 atcatttcat ctgttgcatc cggcttacca tactgcatat tgtctcggat cgttccagag
     2821 aacagaactg ctttttgagg aacaaagccc attaattctc gcaaattata ttgagtcatg
     2881 tcactaatgt ccgttccatt tatttggatc gaaccagatt cgatgtcata taatcgaggg
     2941 atcaaattga ctaaggtcgt tttacctgaa ccagtccccc ctatgattgc gacgatctcg
     3001 cccgacttgg cttggaaatc aatatcttcc aatgcaagtt tttctgctcc atgatatcga
     3061 taattgacat gattgaaggc caatgttgcg ttttttccag caaaagaaac tgttttagga
     3121 ttttcagggt catggatacc gattttttca tccaacactt cattaatacg gtcagctgaa
     3181 gcttgtgcac gaggcaccat gataaaaata gcggaaagca tcataaagct gatcaagatc
     3241 tgcatcgcat aagtcataaa tgcaatcaga ttaccgactt ccaaagtcat atctgctatg
     3301 tagtgtccac caaaccaagt gattgctacg tttgtaccgc tcatgatcaa tgtcatcatt
     3361 ggcatcatca atgcgacgat cgtattaact ttgattgccg tatttgtata atctttattc
     3421 gctaaatcaa aacgattttc ttcaaagcgt gtcttatcga atgctcgaat cactctgacc
     3481 cctgtcaatc cttctcgaaa taccaggttt aaacggtcag ttttcttttg catacttttg
     3541 aataatggaa cagcaaagta catgattccg ccgatcaaaa taatcattac tgggatgaca
     3601 actaagaaga tttttgtcaa ctgatgatct ttttgataag caagtatgct cgcgccaatc
     3661 aacgtgattg gtgcattgat catcatacgt aaaaacattt gtgtaaccat ttggatttga
     3721 gtcacatcat tggtcgttct tgtgatcaaa gaggccgttc catatttatc aaacgcatct
     3781 tttgtcagac tctctgattt tttatagaca tccgtacgca attgcttacc cagtttctgt
     3841 gattcacgag tagcaaaaaa tgtatttgcg atagcagcta agatactgat caaagaaaag
     3901 ccgatcatca caaaacctgt atgccaaata taatcgacat ctccttgcgc taccccttta
     3961 tcaataatat tggaggtaag tgtcggcaaa tataaatctg ccagtacttg gatcaccatg
     4021 aaaactgcag ctgcaattgc tgaagtcaag gagatccgtt ttacgatttt tagcatctag
     4081 ttcccttctt tctatttata tactccgttt ttcagccaag aaagtttcaa attgaattca
     4141 ctgattgctt gctctactga gtaatcttca gatgttgaaa ataagcgata cgaatgcgca
     4201 attgttgtaa atacagtatt catcactaat tggatcagta attccaattc atgatcattt
     4261 tttactttca gcttcgtccg atcgatcaat tcaagcaact cttttgcatc ttgtttgtgt
     4321 tctttatgtg gatcgtgagg cgttttttgg cgactcgtat gaggagcgac ttttcttgag
     4381 gcacggtaat ccatgttcat aaacaagtta cgataaaaag aagcattctc gccttccaaa
     4441 atctcataaa tcattttaga aaaataggat tcgaatcctt tgaatagatc accatcggat
     4501 tctttcatta gttgtaacat atctttagag ctgtcacgtc tcattgtctc aaagtaataa
     4561 aaataaagat cctctttatc ttcaaaatac tgatagaaac tgcctctagg gatatccgct
     4621 aatttgacga tattagcaat cgaagcttct tttaagggta ctctagaaaa ctcgattctc
     4681 gcagcctcga ttagtctttt ttgtttttct ttaggcaaat ggaaaaatgt ctgtgtcggc
     4741 atatggattc tcctttcttt caagatgaca cattgtcata tgacgctatg tcattataac
     4801 acctcctacc tgttttgcaa gacatttgca tagttttttt cattatcatc cgatacatta
     4861 aaaaagtgat aagaggaatc cttccatttg aattaatgag agttgcccat taaaatagcc
     4921 acatactaaa caaaggatga gataaatggc ccaatcaatt agtgtccaag acttcaataa
     4981 attgcctctc gatgctgaca gcatcgtttt agatacaaga aataccttag attacacaaa
     5041 aaaccactta agccactcgc tttctatccc cgctgctatc ttgccaagac aattaaaaaa
     5101 tctagatcca aagaaacttt attatattct aagctataca ggcaggcgat cagaagcatt
     5161 agccgatcaa cttactgcta atggttttcg tgctgtttat atcattggtg ggatggaagc
     5221 tcttcagtcg agtgttgctt gaatattgct tgttagattc aaaagaggct gtgacaaaaa
     5281 atcgtgtcac agcctctttt ataccctgtc tttttttagt tatttattct tcaaccttat
     5341 caatatgact tgatagcctt ttctttttcg agtaaactga ttttgttagt catagttata
     5401 acaatcatag caataaaagg agaaggtaag catatggcat ctgttttagt agtcaaaggt
     5461 catcccctaa ctgcagaaga atcgcgcaca gttaaggcat tgacgtcttt tttaacaagt
     5521 tataaagaaa atcatccaga tgatgaagtg actgttttgg aactttatcg cgatgatatt
     5581 ccggaaatcg atgaagaatt attatcaggt tgggaagcat tacgtgctgg tgcagaattc
     5641 acttccttat cagaaagtca acaacaaaaa attgctcgtt tcaatgaatt gactgatcag
     5701 ttccttgctg ctgataaaat cgttatcgca aacgccttat ggaatctaaa tatcccaaca
     5761 aaattaaaag cttggttcga taccgtcaat gtagctggaa aaacgttccg ctatacagaa
     5821 aacgggccag aaggattagt gacaggtaaa aaagcactgc acatccaatc taatggcggt
     5881 gtatacaacg gacaagactt tgcctctcaa tatgtaaaag gtattttaaa ctttgtaggc
     5941 atcgatcaag tagatcagct attcatcgaa ggaatcgatt atgaccctga ccgtgcagat
     6001 gagttgatgc aaaatgcatt agataaagct gctgctttag gtaaatcatt ttaaaaattg
     6061 agataaatgc atacaaaaga gacagaggaa aaaatcttca aagcagcatt tgtgccttgg
     6121 atattttccc atctgtctct ttttgttatt ctttctgctt tttcaacgga ttttcttcat
     6181 aaagagaaga gattgttgtg taccattcaa aaacatgagt aatcactact ttagctgctg
     6241 cataaacagg aatccccaag atcacaccga tgattccgaa caatttccca gaagtcagca
     6301 gaactaataa aatcgttact ggatggattg ctaactgatt ccctagtact aatggagaga
     6361 tcaagcgtcc ttctattgtc tgctctactg caaaaacgat cagtactttg atgatcatga
     6421 atggacctgc tacaatggct aaaaagatag ccggaatcat cgctaaaaat gatcctaagt
     6481 aagggatcag gtttaaaaaa cccgcaataa tccccaacgt gacagcatac tctaaaccaa
     6541 tgaccgcaaa accaatcata aacatgattg ccacagcaaa agccacagtt agttgtcctc
     6601 ttatataaga agaaacttga ctattcattt cactcagcac attcaacgtc ggtttttgca
     6661 tgcgtgtcgg taaaaatttg acaaaataag gtgctaattg tttaccgtct ttcaatagat
     6721 aaaataagat aaacggcatc gtcagcagag ccactaaaat agtcgctacc gcgccgacaa
     6781 aacttccaag actctgaact gtactcttag atatatcttg gatcatatcg cctgccgaat
     6841 tcatgaactt atcacctgct gtttccaact gttcgcgaaa ttggttgaac agcgggtccc
     6901 gcaaaatctc ggttaattta ttatcaatcg tatctacata ttgagggaag ttactgatga
     6961 agctcactgt ttgttcctga atcttaggga tgatcactac gctcccccat gcgattagtg
     7021 caacaaccaa aacaaacagc ccaatgatac tgtaaagcct tggtactttt cgcttttcaa
     7081 agtaatcaac taccggattc atcaagtaat acaagattcc tgctaaaatg ataggcagac
     7141 ctacgattgc taaaaattgc cagattggtg caaacaaata tgaaactttt gtaaataaaa
     7201 agacgatcag caatattaac aatacaacaa gtaaggctgt gactacttga ttatttaaaa
     7261 accagcgcca aaaccacgat accggtctgt tcttcttatt ttttccttcc ataattcctc
     7321 ctgttagtta taaaaaattt ggcttcccaa accaatagca ggcagtctat gcggatgaag
     7381 atagattcca tttgcaattt gtccttcttc tggacaagca tcaaaaatca atgatacgtg
     7441 agctactgtc tttaaattcc cattggccat cggaccgaca taatcgatcg tatatacctg
     7501 atcatcaaaa gcaattgttc cgcctgcttt caaagaaaaa ggttcgtctt ttgatacttc
     7561 ttgaatcacc gaatattttc gtaaggcagc tgttgctgtt ttatcgaaca aaatcagcat
     7621 gggttcttcc ttgtttattg cttctgtccc aatttctgta atctttgcct gaatcattgc
     7681 actctctcct ttaattgctt tcaaaaacag tataacacat tctcattctt tagccgtgtg
     7741 gaataattat gtgatagaat aaaaacgaaa actatttcat tacaattagg aggaatcagc
     7801 tcatatgatc gaaaagataa ttttaggaac ctatacgcgt cgcgaaagta aaggaatcta
     7861 tacgatcgac cttgatacag aaaaagaaga attagccaac ctttcattag ctgttgaaga
     7921 aaatagccct acctatgtag caaaaagtaa agctggcaat ctttacacag ttactagtgt
     7981 ggatggatta ggtggtgccg gtgcgtacga taaggatttt cattttttga atgcggtaac
     8041 agagtctggc gctcctttgt gttatgtagc ggttgatgaa gcacgtcaat tactatacgg
     8101 ggcgaactat cataaaggtg aagtaaatgt ctaccatata ttaggagatg gcgaactgaa
     8161 agcagcagat tcaatattcc atcaagaagc gacaggtcct cataaaaacc aagatcatgc
     8221 gcatgtccac tatacggatc tgactcctga ccaacgatta gtcgtatgtg atcttggtac
     8281 agatcgtgtg tatacttatg atgtgtccga aaacggcaaa ttgaatcttg taactacctt
     8341 cactgcagag ccaggaacag gccctcgcca tcttgtcttt catccaaatg gacaattcgc
     8401 ttatttattt ggtgaattag acagcacagt ccgcgtgctt tcttataata aagaaacagg
     8461 tgcttttgaa gaattacaga aaatatcgac cttgccagaa gaattcgacg gtgaaaatgg
     8521 aggggcagct atccgcattt caaatgatgg caagttcctt tatgcttcta accgaggaca
     8581 taactcgatt gctgtattcg cagtttttga agatggttcc cacattcaaa acaagcaaat
     8641 catctcaaca gaaggggatt ttccccgcga tttcgcacta gatccaagca ataattttgt
     8701 cgtgtgtgcc aatcagaaca ccgataatct gacattatat cgccgtcatc ctgaaacagg
     8761 attactggaa ttactgaaaa aagatgtcta tgtaccagaa tgtgtctgtg tttattttga
     8821 tcgttagtaa gaaaaggaga atgaaatgaa tcagcaagac gtattagaca gactacggga
     8881 agaactaaat attcctttct ttgatgggaa aatcgaagat aaagagtata gcgaagagga
     8941 atatcagaaa ctcaaagccg atttacagaa ctactttgaa caatatgtac agaatgtaga
     9001 aaactaatca gctttccata ctatctgaaa agaacatcag gacaagactt ttccgtctat
     9061 cctgatgttc ttttctacaa ataaaaaacc gccgagatgg ttagactcga cggaaaagga
     9121 gtatttactc gattttgagt aagtacaagg ttgttgttgg ttataggtat gtcattatca
     9181 taaaggattt tgatcactct atcataaagg taatattaca tttatattag ataactctag
     9241 tttttattgt tatcaaagat ttcttttatt ttttcaacaa caaattagtc attttttgga
     9301 tggcagctgt caattggtct gtcgcttggt cttgttttgc ttcagatgta ttgaatagat
     9361 cttcatctac ccctgattca agatcgatac tttggatcat ttcttcacag cctgctacat
     9421 atgaaagata agctttttca aaatttttat gaatgcccat tgcttttgct ggtggacgca
     9481 aagtactgac tttcataagc attgcccgat atttttttgt tccttcttca aataacagga
     9541 tgatctcttc aagagtcgat ttgtccagtt cacttgtttt tccttcatca attgcgtttc
     9601 tgatcacttc atatttcgga tgcattcctt ctccgattgc ttctgtttcc ttgacgattt
     9661 gatcgatgga ctgcacataa tagccaatat tcggtaacat gttcgttttc ctactttctc
     9721 cattgttgtt attatttatt ctacttgttt ttatcctcaa atgacaagta cttgaaaaaa
     9781 tttaatggtt tctatacagc tcgccattct tattcgtgct caaagaaacc atctgctaaa
     9841 ctatattgtt tccctgcgac aatgtcatat tggatcaatt gatattcgtc gtaaatctct
     9901 tgttgcgagc gattgaattg cgcttcttta taccactgtc cgttttgata gtacagttct
     9961 cgttcaaacg ccggaagttc ctgttctaat gataaaagca gctgataaaa gccatttgtt
    10021 gtctgattcg tctgttccat tagattcgct gcaaaataaa acggactggt gattgcatcg
    10081 tgagtcgttt gcttttctaa ttctccttta ctgtcgaaca taagaaattg tgtttcatgc
    10141 aatgtttgtt tgtcattttt tgcttggatc gtatctgaat agatccctgg aagatgatcc
    10201 ccccaaaaaa caactaaagt ccttctagaa agattcttca attcttccgt gaactgcttc
    10261 agtgccgtgc tgctatagga aatatcttgc agataattct ctaagtcaag tgtcccactt
    10321 ccatctgaag tttttgcagg atagtctaga ttatcatact ttccatcgta gggcatatgt
    10381 gtctgcatcg tgactaaatg aatgaactga ggtgtttttt cttccttgag aagtgtcatt
    10441 acttctttgt aagctgactc atcagaaata tatggattat tctctatcgt atccgtatag
    10501 gtcatcgtac gctcgctgat gaactggtca aatcctaatg tctgataaac atcctctctt
    10561 ttatacatcg aagtattgta tggatggatc gctgtcgtct ggtatgattg tgcgtttaac
    10621 gctgaaacga tagaaggaag ctgatccatt tttggtacaa gcatcgtgta aggggtggtg
    10681 agttgcgcat taaataacgc catagaaaaa ccagtcaatg cttcaaattc gatatttgct
    10741 gttccaccgc catagttttg agaaagcata ttgccactat atgtttgatc agctacttca
    10801 taataatctg ccaatggctc accagatact tctacgccgt ttaatcgact aggatctgag
    10861 aaactttcac tcatcacgaa cacgatgttc ggcgactctt cctctacagt tttatttttt
    10921 tcatcggcta gcttctggta tttttcagtg atttctttga tcttttcttt cgaatatcct
    10981 tcaggttcat ccattggttc taccttcaga ttgtacaaaa acccaccgat aaaaccagtg
    11041 ttatagtagt tcattttctg gctgtaaggt atccatagtg ccgttttatt atatgctttt
    11101 cgcaacaaat tatcgggatt gttgaaatta ctgatatacc ctagcagtcc aattgccaca
    11161 agcagtgtcg ttaatcggat caattggaat cgccttcctt ttttcaggct tcgaaacatg
    11221 taccagcaaa acaatcctat cacggttcct gcggcagcta agatcactgt aaacagcata
    11281 gtgccggtca tatctttcag caatccgatt tcagtgatca tcttcaaatc gtctggataa
    11341 atcggttctt gccgataact cattttcata taatttgcaa aacctaatac accgatggct
    11401 acgacatacg taagggaacc taaagggaca gatcctgcta gtgcaatcag aaaaataaga
    11461 ataatcagca agacgagaca ggctaagaag aatttttccg tatgccaaga aaaagcaaat
    11521 ttcaacgcaa ggtctacgga tagatcattt tgacaccact gcaaaaataa attactaaaa
    11581 acaacaagaa aaaagatact gatgattgct gctgttcctt ttaaaatctt tttctgtttg
    11641 gtcgaaagtc tgcttatata tcttttcaaa tgcttgctcc ttcatttcta tcaataaaag
    11701 aatgttgctt ctcttatttt agttgtacga aattcgaaag taaagaacgg aaagaagaat
    11761 taatgaaatc caaatattct ctttctttat ggcctttctg gtttctttaa taagcggacc
    11821 tttcgtactc cagaaatttt ttctagctgt tgtttcactt gattgagctg ttcaaaatca
    11881 gtactgtcta tgtcaatcaa tatgtagaca tgctcattct tatggttacg cgatatatct
    11941 gcgatcgcta gctcgttctc attcagcaga gaaaatatct ctgctaatat attggttttc
    12001 ttttgataaa atatagtgaa tcgaaacggc gcttggaaaa acattcgtgc ggatggataa
    12061 ttgaccgctt ctctaaccgt accgaacaaa agataatctt ttaaggcttc aactgccaaa
    12121 cgtccgctgt ctgccaaagc ttcctgagtc gatcccccta gatgaggcaa cataagtata
    12181 cggtcatttt ctaagaactc ttcttctgga aaatcagtca agtatttagc cagatgttgt
    12241 ttttccaatg cttgcataac agcatattta tcaacaattt cacttcttcc tacattgata
    12301 agtacagcat cttttttcat tttttctata ttcgcctgat cgatcaatcc ttttgtatct
    12361 tctgtcaacg gcagcatgac tacgatgtaa tccgaggtag aaagaactgt ttctaaatct
    12421 gcttgccgaa cataatccaa ctgggcatcg cggatagaat aacccaagac atccatccct
    12481 aagctatagc aacttagcgc tacttttgtg cctatcgctc caagaccaag aagaccgatg
    12541 gttttgcctt gcaattctcg tcccacataa gcacttcttt tgttttctgc ctgttctaaa
    12601 atattaggac ctgttagtgt ttgtaccata cgacttgctt cgattatcgg acgggaagat
    12661 aagagcaaac agcacaaaac aagctctttt actgcattag catttacacc tggtgtattc
    12721 atgacgatcg tcccgttttc agaagctttt tcaacgttga tcgtgttcac cccaacacca
    12781 gctcttgaaa ttgctagcaa atctggtgta agccattcat ctttcacttt cgtactacga
    12841 ataactattc cttcggctgg caaatcatct attattttga aatattcccc ttgtaacttt
    12901 tctatctctt gttctggaat agcatcaatc aaatgaacgt gatacataaa accccctcct
    12961 tactaacaag tatctcgaaa tttctgcaat tagacaactg tttaccattt gacttcctag
    13021 aagcaaaaag agcagttaga gcagagtagg ctgagtgata aaaataaggc tatgacaagt
    13081 tactgccata agccttattt tcgagagcaa aatattgagg gtgagatatc ttgataaatg
    13141 gtgttccgtt agctgacatt gataataaga ctaaatttca aaaaagttga aaagcaaatt
    13201 tcgtcaatct cttcttattt cttaaaacta agtggctttt tcacaacctc tttttatcta
    13261 ataaccactg tttccaactc aactaatttt gcccacgttt caatttgatc tgttgttaga
    13321 tttagcgaga caacggtatg atgaccgcca cctgcctgaa tccatgaatg gacaccttca
    13381 tggaaattcg gtttagtttt ccataacaca cgtgcaacag gtaaattagg tgcttcagtc
    13441 gttggttcaa aggcttctac ttcattgatc agcagtttat aatgcgtacc gaaatctgcc
    13501 atcgatacga ctaccccttc tcctgctttc ccatcaaata caagacgcgc cggatcttct
    13561 ctatctccca ttgataaagg agaaacaacg attcttggtt tcgtcgcagc aagcgtcgga
    13621 tctacttcca tcatatggga ttccaagatt gcttcttggc cactagctag ctcgtaagta
    13681 taatcttcca tgaatcctgt atctttccct cgagccatga ttttcagcaa ccgatcaatc
    13741 gctgcagttt tccagtcgcc ttccccagca aaaccgtatc cttctgccat caaacgttgt
    13801 acagctagtc caggtagttg tttcattcca tacaggtctt caaaattagt cgtaaaagcg
    13861 ttatagcctc cttcttctaa gaaacggcga ataccgattt cctgctgagc ttgtactttt
    13921 acatgttcct cccatgtctt ttcttcataa tcaccatagt cgaaggtata caattccttg
    13981 tactcttcaa ataattgatc gacttcttcg tctgatacgc gatcgattac ttgtacaaga
    14041 tctccgatac caaaataatc aacagtccaa ccaaattgaa tctgtgcttc cactttgtct
    14101 ccttctgtga cacccacgtt tctcatgttg tcaccaaaac gagccacttt tattccaaaa
    14161 ctttcattat aggctactgc aacatccatc caatcagcaa tctctttttg gatctcaggt
    14221 cgtttccagt agccaacgac gattttattt tgtttattta atcgagcatt gatgaaccca
    14281 tattcgcggt caccatgagc ggattgattt aaattcatga aatccatatc gatcgttttc
    14341 caaggaatgc tttcgttata ttgcgtagct aaatgaagca atggtttttg tagaagcttt
    14401 gtcccgcgga tccacatttt tgctggtgag aaagtatgca tccaagtgat cacacctgct
    14461 acttcttctc gataattgac ctctttcatg atttttgtga tcgtatcagc agtaactgct
    14521 aattcttgaa ggcggattgg ataaggcaat tggccatttt cattcagttc atcgaccatt
    14581 tcttgtgcat gtttctttac ttctcgcagt gcttcttccc catataaatg ctgtgatcct
    14641 acaacaaacc aaaattcttt ttctccaata ttcaacataa ttagccactc cttttatttg
    14701 ttttgtccgt aatacgcatt ttttccgtgt tttcgtaaat aatgtttatc taaaatccgt
    14761 tgaggcagct cttctgaaaa tgaattgagc tgtctggtaa ataaattcat cttgcatact
    14821 tcatctagta cgactgcgtt cattaccgca ctttgcgcat ctttccccca agtaaatgga
    14881 ccgtgtccgt gtaaaagtac ccctggaatt gctaagggat caattttgcg ttctttgaat
    14941 gtttctatga taacttttcc tgtttcatat tcgtacccgc tgtcgatttc ctgttgtgtc
    15001 aaaaatcgag cacaaggtac cgatccataa aaagtatctg catgcgtcgt ccccatcgca
    15061 ggaacatcca atcctgcttg tgcccagatc gtcgcccatg tcgagtgagt atggacgatt
    15121 cctccgattt gaggaaatga acgatataaa acagcatgag taggcgtatc cgaagaggga
    15181 ttgagtttac cttcaatgat atgattgtcc aagtccacaa cgaccatgtc gtctgctgtc
    15241 atctcttcat aactgactcc gctaggtttg ataacgaaat atcgtgtttc aggatcaaaa
    15301 gcgctcacat ttccccatgt atatttgacg agtccgtgtt taggcaagtc aagatttgct
    15361 tggtatactt cttctttcag ttgttccagc attttctatc actccttttt cttgcaattg
    15421 atgaatcgct gttttttcaa tgtcgatccc ctcacggtaa cgtctcataa atatctgata
    15481 gcctgctatt tcttctgctg aaggtgtgat ggtgattcct tggtcttgtc caaacacgtc
    15541 ttctgccaag aagttttcta aagacttccc atgtcgatcc atcatatagg ctgctaataa
    15601 cgcgattccc cacgctccac cttctccggc tgtgtccatc actgtaactg gtgcctccat
    15661 agcagatgct agaatccgct gtccaacttc tggtgtttta aaaatccccc catgccccac
    15721 taaacgatca atttggacat tctcagattt caatatatcc attccgattc tcattgcacc
    15781 aaaagcactg gctaaatgga tccgcatgaa attcgctaaa tcaaaacggc tacctggtgt
    15841 acgtacaaat aatggccttc cttcatttac tcctgtaatg ttttcaccgg aaaaataacc
    15901 ataagaaagt aatcccccgc aatccgtatc gccttctagc gctttgttga ataataccgt
    15961 gaataattta tctctgctta tctccatacc caaagaattg gtaaattctt caaaaatact
    16021 gacccaagca ttgatatccg aagagcagtt attcgtatga accatgccta ctagttctcc
    16081 tgaaggtgta gtgaccatgt cgatttccgg atggacattt tctagttctt tttctaatac
    16141 gatcatagcg aaggcggaag taccagccga aatgttccct gtccctttgg ctacactgtt
    16201 cgtagcgacc ataccggttc ctgcatcccc ttctggcgga caaaccggga ttcctggtct
    16261 caaatttccc gtagggtcga tcagataagc ccctgattcg cttaacttgc cagcttcttc
    16321 tcctgctact agaactttag gcaaaatgtg atccaagtca atcgctacgt gcgctttttc
    16381 gattaactga ccaaaaatat ttttcatttc ttgatggtag gttttcgttg aaggatcgat
    16441 aggaaacatg cctgatgcat ctcctacgcc tagtactttc tcaccagtaa gctgccaatg
    16501 gacataacct gcaagcgttg tcaaaaaatt aatttctttc acatgttctt ctttattcaa
    16561 aatagattga tacaaatgag cgatactcca tctctgcgga atattgtatt gaaatttttc
    16621 cgttaatatt cgttctgctt cttcagtgat tgtatttcgc caagtacgaa atggtactag
    16681 taactgttcc ttgctatcaa atgctagata accgtgcatc attgcactga acccaatcga
    16741 cccgattgtc gtaagattct cgccatagat ttcgaatact tctgctgcca tttttcggta
    16801 actgacgcgc agtcctttcc aaatatcttc taatgaatag gtccagatac cattttctag
    16861 tttgttttcc cactcataac taccagcggc aataggagta aaagatgaat caatcaatac
    16921 agctttgatc ctagttgatc caaactcaat ccctaaagat gtacgaccat ctatgacatc
    16981 taacatactt tgcgcattta cttccttcat aatgatttaa ctccctcctt ctcgtcaaac
    17041 ctgatcaaac cgtcttttta gtagcgctta caatgattat tgtatacttt tgtacgtaca
    17101 tgtcaagcag ttatttacaa gaatacaata aaaaacactt gttttgtacg tacataagtt
    17161 ataaaatgaa attgcttaca aaatctgatc aaccgccttc tcgaaattct agaaggagag
    17221 aatacttatg aaaaaagaaa aaaaagtttc ctcatcgttt atttattttt ttggcgcatt
    17281 tggcggcatt ctatttggat atgatattgg tgttatgacc ggcgccttac cttttttaca
    17341 gcatgattgg ggtttggcag gtaaagcttc tttgatagga tggatcacgt cttcggtcat
    17401 gttaggtgcg atccttggcg gctctttatc tggtcttctt tctgataagc ttggacgacg
    17461 aaaaatgatt cttctttctg cacttatttt tatggctggt tctgtccttt ctgcatctgc
    17521 ccctcacaat ggttcttatt ttctgattgc agcaaggatt cttctaggtt tagctgttgg
    17581 cgctgcatct gccctagttc ctgcttatat gtctgaaatg gctcctgcta gactaagggg
    17641 aagattgtca gggatcaatc aagtgatgat tgcttctggc atgctccttt cctatgttgc
    17701 agattatttg ctaaaagggt tgcctgaaac gatggcttgg cgcgtgatgt tagggctcgc
    17761 tgctgtcccc gcgctgattt tatttttcgg tgttttagct ctaccagagt caccgcgttt
    17821 tcttatgcaa tctggccgct tggaagaggc aaaaagagta ttgaactata ttcggacacc
    17881 aaaagaagct gaacaggaat tcgaacaaat ccagctgaat gtcaaacaag aaaagacaac
    17941 cggaacttct tggcatactt tgtttttaga aaaatatcgt tccttagtca ttgccggtat
    18001 tggtgtagca gtattccagc aatttcaagg agctaatgct attttttact atattccgct
    18061 gatcgtagaa aaagcgactg ggcatgcagc gagcgatgca ttgatgtggc cgatcatcca
    18121 aggaatcatt ttagttgctg gttctttgct ctttttggtt attgcagaca agttcaatcg
    18181 gcgaacttta ttgaaaatag gcggtagcgt gatgggactt tctttcatcc taccagctgt
    18241 tttaggaact gtactggatg ctcatacaaa ttcgttgttg attctcttgt ttttatgtat
    18301 ttatgtcgca ttttattctt gcacatgggc tccactgaca tgggtaatcg taggcgaaat
    18361 attcccacta gctgtccgcg ggcgagcatc tggcctagcc tcttctttta attggattgg
    18421 ttctttccta gttggcttgc tttttcctgt gatgactgct tctatgtctc aagaaatcgt
    18481 tttcggcatt tttgggatca tctgcttttt aggggtttta tttattcaag agatcgtacc
    18541 agaaactcgt gggaaatctt tagaggaaat cgaacaaagt gcatctaaaa aaacttatcc
    18601 taaacgtatt tctatccatc attcttaaag aggttgtgac agaagtggtc agcttcaaga
    18661 aataagaagg aaccgcttag tttccagtca caaggaacaa tttcaaaaaa cagcttctca
    18721 tgtttgatga atattgtgac ttgtgaccag ttggtaggag aacaccgttt agtggagagg
    18781 tggtgaaaga aacgttcagc cttgagcgat gacaaaagct ctcacaaaca ttgcgacgag
    18841 taaccgtagg agcaataaga ggcggtaaaa acccgtctct tatttttcgt tttctttcac
    18901 tgtttcccgt tcaactagta caggttcata gagaatattt ggctgtgcct gtcctttttc
    18961 aatcgttgtg acgatccacc gtgcggcatc ttgtcccaac ttttcttttg gatgcgtcaa
    19021 tgttgtcaat tttttattcc ctaaatggct taaagaagaa tcgtctgttc ctacgatcga
    19081 taggtcatct ggaatatgat agccattttc tgtcaactta tctagcatta aactagctat
    19141 ttgatcgtta tagcaaatga tgccatctaa agcttgttct tctttcaacc gttgtactgt
    19201 tttttcagcg attgtttctc gtgtttccgt ggtgaaagta atgatatctt ccgtcaaaaa
    19261 acgcacatta tactgttcac acgcgctgat aaaacctttc atcctgtatt ttccttgaag
    19321 atcgtcgatt tttgtgatga acaacagacg ctgatgtcct ttttttatca aatattctgc
    19381 tgccataaaa ccgactttca catcatctaa acaaatataa gaggcattta actcttcata
    19441 agcagcattg atcatcacca tcggaatgcc ttgttctctc aaagcaacat aaagtgctaa
    19501 gtttgggtta tactgattac ttttcgtagg ctcaacgatc aaaccatcta ccccataagc
    19561 aatcattttc ttcaaacact ctttctccaa ttcgtgatcg ttattcgtac tggctaaaag
    19621 caatgaatac ccagattctc gtaattcatt ttcgattcct cggataatcg acggaaaaat
    19681 ataatcagag agatatgtgg tgatgacacc gatcgttttt gttctgttca atggtgtttt
    19741 ttctttctta tagctgtcat ctacatatgt gcccgaccct ttttctttac gcagatagcc
    19801 ctcatttacc aacacagcga ttgcttgccg aatcgtatgt ctgctgacgt catatatttc
    19861 ttgcagcttg aattctgagg gaatggttgt atttacttcg tattcctcac gaaggatctt
    19921 ttgttttatc tcttctgcaa tatcttgata ttttgccatt tgccttgccc ctttttattt
    19981 gtacgtacat atatcataac gagtctgcaa ggtttattca agcaaaaatc aaggtttctt
    20041 gtgctcataa ggcatacgga acaggttcac caaattctgg aaatccttgc tcattccacg
    20101 taaagcattg cgcgttcgcg tgccgattag gattgtctaa cggatcccct ttttggttct
    20161 tctctggtcg agcatgatag atcaaaatat caaagcaccc gtcttctgaa accgtaaacg
    20221 agttgtgacc aggaccaaat tgcttatttt ttttagaaga aacgaatact ggctccgata
    20281 atttatgcca tgattctttt aataaaagat tcttgtgctc atcagcccac agcaggccca
    20341 tggcatagtt ttcatctgtt gcactaccag aatacgtaat gaatattttc ccattgcgag
    20401 taaggactgc tggaccttca tttactgaaa aaccccgttt ttcccattca tactcaggta
    20461 tagaaaggag gatctgcttc ccctttaacg tccaaggatt atccatttcg gatagataaa
    20521 gattagaatt cccagtaatt tcaggatctt gttgggccca cacataatat agctttcctt
    20581 gagaagagaa agttgttccg tctaaactga aagtttccct tttcgttttt atttgtccct
    20641 tttctatcca atctgtattc attggatcta tatgctgatt ttcaagtacg aacatgcggt
    20701 gatgatgaga ttcatcacgt atagttttat gattgcttgc agcaaagtaa atataccatt
    20761 ttccattgat ataatggact tcaggtgccc agatcaattc actcatcggt ccttcttcat
    20821 gagcctgcca tacaatcagg cttgcagcat gttctaattc attcagtgac tttgcccttc
    20881 ttaattcaat cacttggtag cctggaaccg atcctgtaaa ataataataa ccatctgtat
    20941 gtttatatac ccaaggatct gcccgttgcc gaacgatagg attattataa agtgtcttca
    21001 tcataacaaa tttcctcaca ttttctttat tctaattaca ttccaagagt atttttctat
    21061 ccctacattt aattcgtcat gtttttctat tgaaaaatag tttatttcag gttttatttt
    21121 ttctggttct tcacgtgtat ttttgtccaa cagatcgcta ctggttaatg tgtagtgctc
    21181 tccttgatct agcaaattga aatcatgttc aatcgttatc ttttgttgtt catttgtgcg
    21241 attgatcaag aaaatagtca gctgattgcc gttatctacg atcacactgt ccacataagg
    21301 aacatttttt atcttttcac aatcataaac agggcaaatg atttgttgtt tcaatacttg
    21361 acctttagca tatttcgata agtgttgcat cacataataa gttggattcc tccatgcttg
    21421 tcctttagca tctgtcagta ttaaaggtat tgtgtttact aacaatgatt gacaactaat
    21481 ctttacgcga tctgcgtgtc gtaaaatagc cagccctaat gaaccaaata ataatgtatc
    21541 ttccatagta aagtaacacc aatcgatggg actaccgact tcaaaatccc tatgtctttt
    21601 ttccggttgg gcatgtacat tccattcatc aaacgctaga tacattgttt tctcacttct
    21661 caaatatcct tttacataat cacaagtagc aacgatttct tcaatttgac gatcgaatcg
    21721 ataagctttt gcaaggtatg tcgctgtatc atcacgctca tttttaggag gtttagtcaa
    21781 gtcttcttca tcatacttat caatatagtt atgcaaagct aaataatcta cattctcata
    21841 agcttcttct aatgcgatac gatcccattc agggtacgat ggtaaacgtg gcgtagagct
    21901 tccaactaag attgtttcaa ttgaatcatc cactaacttc atgacttttg aggcttcatt
    21961 tgctaaccta ccatattcat aagcactctt agcccccact tgccatggac cgtctagctc
    22021 attccctaaa caccataatt taacgccaaa aggctttttt tgcccatttt ttattcttaa
    22081 atcactccag aaggttcctt ttggaaaatt acaatattct actaaatttt ttgcttcatc
    22141 aattcctttt gttcctaaat tcaccgtgaa tatcggtttc gcttgtacat gactgatcca
    22201 tttaaaaaat tcgtggagtc caaaagaatt tggttctata cctcgccatg ctaaatcaat
    22261 tttttttggt cgttgttctt tcctacctac agtatccacc caatcataac cagatgtaaa
    22321 gtttcctcca ggatagcgaa tgacacctaa ttctaattcc tttacataag agaggacatc
    22381 ttgtctaaac ccgtcaccat cagctgtttc atggcccggt tcataaatcc ctgtatagac
    22441 gacacttccc atatgctcaa caaatgagcc aaacagccga gaactgatct ctcctaccgt
    22501 aaaatcctct ctgattttta ctttcacttc ttcgtccaac agctttccct acctttcatt
    22561 tcctatagtc aagataatag atacaagttt ccatacgcca ccagcaaaga taaaaataaa
    22621 aggagggaaa agaaatatga gcagtacaaa tcctaataac aatacgcaac aaagaatatt
    22681 tctcaaaaaa tcaaaaaata ctttccatgc actttgttca aaaatttgta aaaatgtgat
    22741 atctttgttt tcagaaatca catatatcca ggataaaaga aacatggaat aaataagtaa
    22801 aactacatat ccactaattg aaagtacgat tgtctgttct tctaataatt gattaacaag
    22861 aaaataaata atgatcgtta acagactaag gaacaagttc ttaccaaaat gttgctttat
    22921 tccttgaaag aaaaaataaa tgatatttcc tgatccctca cctttccatt gcgccattac
    22981 ataaaaaaca gcacatgtag caggcacgat agtaataaca ggcaaacaca cgattaccca
    23041 gagaatacct aataagatgt aatcagaaac cacaatcaac tgtccataaa gtttagtctc
    23101 aactattttc atcttcctca ctctttcatt ccagacatag ctgttccttg aacaaaatat
    23161 ttctgtgcaa aaatataaac cactagtaat ggcagcattg aaataaccgt tccagccatt
    23221 acaggtccat aaaaagaaat gttctgccct gtaaataaag ctaaccctgc tggtaaagtt
    23281 ctcatttttg aactacttgt caatatcaat ggataaagca agtcattcca actattcatc
    23341 agcgtgaaaa tccctaatga taaaagagta ggtttgctca atggcaacat gattttcaaa
    23401 aaaatattaa actcacttaa tccatcaatg cgtgctgcct cttccaaaga atctggtaaa
    23461 gtaataaaaa aggaacgcat catgaagata ccaaatgcag ttgtcatacg aggaatgatc
    23521 aaacctgcat aagtatcaag catgccaagc aaattgactt caataaatag aggaatcatg
    23581 aagacttgga atgggatcat cattgtcagc aaaacgaaat agaacaaaac tgattttcct
    23641 ttgaaacgca tacgagcaaa tgcatacccc gcaagagaat caaagaatac agaagtgatc
    23701 actgtccctc cagcaaaaat cactgtattt ttgatgtaat ctaataaagg gatcgttgtc
    23761 caaaccttaa tatagttatc tagggtatag ctatctgcaa atattctagg cggaaatgag
    23821 ataatgtctt tttcgtgttt aaaagaagaa ataatcagcc acaaaaaagg aaacgcaata
    23881 accaacaata taactagcat actaatcgtt cgaatgattt ttttaccact aactgctttt
    23941 cgactattca cagtaactgt aatcgagctt tctggtgcca tacaggtttc cctcctattt
    24001 catttgtttt tctttccgtg acatgtacac attagtggag atagctatag ttgcaacaat
    24061 gataaacaaa accgaagaca gtgctgatgc atagcccaat tcataaggtg ctgtaaatcc
    24121 tcgactgtaa atatattgaa cagctgtttc tgtcttaaat tgtgggccac cagcggttgc
    24181 aacatatact tggtcaaaca cttgcatcga accaatcaga ttcgttaaaa tacaaaaacc
    24241 taaggaggga acgatctgag gtagcgtaat gttaaaaaac tgctgtcgat ttgttgcacc
    24301 atccatttga gcagattcat acaaagaggg agagattccc tgaatagcag tcaagagaat
    24361 cgtcatagta acaccaaaat tcttccaaac agtcatgatg gctaccgtcg gcatagcaag
    24421 ggttggatcg cgaaaaaatt gagggatcgg caagccgact tgtgaaaaca agtaaggaat
    24481 cgcccctaca ttcggatcaa gcaacataga aaaaataatc gcaattgacg tcaatgaaca
    24541 aataactgga atgtaaaatg tcgaacgaca aaaacgattg aatctggtat ttttagataa
    24601 tgctactgct gctaataaac caacgataat ttgtgttggc gtttcgagta cggtgaaata
    24661 taaagaatga atcaacgaat taactgctcg ttcatcacta aatatacgtg tgaaattttc
    24721 aaaacttaca aaatttcttg atgtaaagaa aatattcaaa tctgtaaaac taatagcaaa
    24781 tgttcctaaa agcggtatga cagtaaataa taataaaact aaaaaagatg gagttaaaaa
    24841 caaatacgca gcacgatcag gacgattcca atatttggtg aatccgttca tatagtccac
    24901 ctcatctttc attttgataa aatatacaat cttggtttaa acgaatctga ataagatatc
    24961 cgaacaatcg ctgtgatttt tgcaataaca cctatctgca aatactaggt cgatcattca
    25021 gatatctgta tcttgccaac agtctatcct gtataaagtt ctgtactatt tttgcagtaa
    25081 ttgattgatg gcatcatctg catcgttcat gagtgtctca ggatcttctc ctgctaataa
    25141 tttttcaatc agtggattga tgatatcgtt attgatcgca gagatttggg taaaacctgg
    25201 taaatatggc tctgcatagt ccatttgttt cgataattca gatacaatag gatcattttt
    25261 tacttcttca tcttttgcta ctgaatccaa gtaggcagga aaaccatttt cgatactcca
    25321 ttttttacca atttcagttg tattccaata tttcaaaaac tcatagacag cttctttttt
    25381 attattatct gtacttgccg gaatggcata tcctacgcca tctaaaatag ctgttttttt
    25441 gtctgaatca ctcccttgtg gtaaggtagt cacattataa tcaatctcgt ttgctttcaa
    25501 tccgttattt aaccatggcc cattgatttc aatggctagt tgaccagcat tcattaaatt
    25561 gtccatttcg gcgccagaaa tcgattctgg accagtcttg tctacatgga tcattttttg
    25621 gatcgctttt aacgttttaa ggttctcagg agacgcaaat tcagacttag tataatcatc
    25681 gttcactaat ttaccgccat ttgctaacat ccagttatat aacggtgcag ttccatcctt
    25741 attgaagaca aaacctgata catttttact actatcagtt aattttggtg ccatttctgt
    25801 caattcttcc caagtagtag gtggttgttc agtatctaat ccagcttgtt taaacaaatc
    25861 attattccaa tacatataca tgccttgtac ctgcatgggg acaaaatact gtttaccttc
    25921 tacttcacct aattcaatag ccgtttcttt aaaatcagat ttatctactc catcatattc
    25981 ccagaaatcg tctaatggtt gtaccgctcc gttttctaca tactgtgcaa aatctggata
    26041 atttaatgca ataaagtcag gtgctttttt agaagaaatc gctgtaggaa gtttttcatt
    26101 caaattggcc caagtcatga tatccatttc aattttgatg tttttatcat ttgttttatt
    26161 aaattcatta acgatttctt gcaatatttc accatcagat gcagtaaacc cattccaaaa
    26221 agtcaaagtc acttctttat cagaatcaga ttctgctgaa cttccgccac cgcaagctcc
    26281 taaaatacct gttgcagcta ccaacaaaga gccaattaac cattttttac ctttcatttt
    26341 ttgttcctcc ttcatctgat aaacgacatc tgaccacatt ccaagatagc ggtttcaata
    26401 aacaattgat tttcccatct tcagctttta catttgttga atgacttggt tttacttgtt
    26461 cacttttagg aagattagtt gcttttgtat caaatccact catttcagaa aaatcaatca
    26521 ctccctctaa tgataattca gacaagtgaa cagttagatt catttcttct tctccacggt
    26581 taactgcaaa tatgacaagt tctttgtcat ttattacggc tatactttct aaatacggca
    26641 cttcttcaaa atcttccgtc gcatagtttg ctgaacgaat ttgtgggctt aacacctctc
    26701 cttgtccata cacagcagct tgcataaatg gataatagat cgtctgtctc caagcttctc
    26761 cgtttgtttc tgtcctgatt ggtgcaataa catttaccaa ttgagcaaga caagcaatct
    26821 ttactctatc tgcatgtttc aataaagtga ttaatagaca gcctaatagt aatgcatctt
    26881 caaaattata gttatcttct agtaaaggag gagcaatctg ccaaggcgct gcttgctcat
    26941 cttgttccgc tgaatgatac caaatattcc attcatcaaa ggacaggttg atctgcttct
    27001 tactatgttt cttcgccttg actgtatcgc acatcgctgt cacttcagaa atgaaccgat
    27061 ccatgtctaa ggaacgtgca agataatgag aaagatcatt tttttggttg ccataatatt
    27121 gatgcagaga caaataatct atttgatcgt acgcttgatc aagaactgtt aactcccaat
    27181 caccaaatgt aggcatttgc cgattcgaac ttccgcataa aaccacctca attgaatcat
    27241 ctacgagttt catcgcctta gccgtttcct ctgctaaccg tccatattct tccgctgttt
    27301 tatgtccaat ctgccaagga ccgtccattt cattccctaa acaccatgtc ttaattccaa
    27361 aagggctctc ttgaccattc gaacgcctta aatcactcca ataagttcct ttaggaaaat
    27421 tacaatattc gactaaatta cgagctgcat ctactccacg agtacccaga ttgacagcca
    27481 tattgatttc ggcccccaca tgctgacacc agttataaaa ttcatgaatc ccaacttcat
    27541 tcgtttcaat tgtccgccaa gctaaatcca accttctagg tctatttgct atgggcccaa
    27601 tactgtcttc ccaacgaaat cctgacacaa aatttccacc aggatatcta atcatgggaa
    27661 tgttcaattc ttttaccaag tgaatgacgt cttggcgaaa tccactttta ttagctgatg
    27721 gatgatctgg ctgataaatc ccttcatata ctgctcgtcc catatgttca ataaatgaac
    27781 tgtacaaccg cggatcaact ttgcctacac gcttgacact actaatcaac attgtggctt
    27841 ccataactga cctcctttaa tttatacatg aataatacac ctcgttgaaa gcgttgtcaa
    27901 taatataaat gttaaactta cttatttttt atcgatttta attaaccaaa atattaataa
    27961 tgattaaaac aaataattta atataacttt tattaacaaa tatgttaata tataagaaaa
    28021 accttttaag aggtgatata tatgcaacta caaataaacg aagaatcctt accggtatat
    28081 gaagcattag ctagtaaaac aaggatcaag atcatccagc tactttccaa aaaaaagatg
    28141 aatgtcaaag atttggcaaa agaacttgga gtgagcagtg ctatcacgac gatgcacgtg
    28201 aaaaagctag aggaagcaaa catcatcaaa acagaaaaag taggacaaca aaaaatttcg
    28261 agccttcgtg tcgataaaat cgatatcagt tttccagaaa aaatattcaa tgcttttgat
    28321 acgaaagaaa catcgatacc tattggtcac tatacaaatt atgcaattga accaacatgc
    28381 ggtttagcta cgatccatga ttttatcggg aaagtggatg aaccacgcta ttttatggat
    28441 cctcgaagga tggatgcccg cattctctgg tttaccagcg gatttgtcga gtatcaggca
    28501 cctaattttt taaatacaga ggatacattg gagatgttgg aagtttctgt ggaaatttct
    28561 tctgaatttc ctttttcaaa tgacaattgg ccttcagata tcactttcag cctaaatggt
    28621 gtggagctag gaacatggac gagccctgga gattttgctg atatccgcgg taaatatacg
    28681 cctgattggt atccagataa tcttaatcaa tacggcttgc tgaagacgat ccgaattacc
    28741 aaacacttga cgaatatgaa tggagaaccc ttgtcaaaca tcacgatcaa cgacatccct
    28801 aaagagcaag acacttggca tttgcgaatc gaagtgaaag acgatgccaa acatgtgggg
    28861 ggctgtactt tatttggtaa aggattcggt aattacgatc aggatatcaa attaaaagtt
    28921 tactacagct gatatttttc ttttctattt tataaaacaa aaacagccaa tccctatgaa
    28981 gggacggctg tttttgcttt attgttattt ccagaaatca tccaaaacgg aaattggcaa
    29041 atgtcgttta tgttgtgtct tgttccacca tgcttcgatt ttttcttgtg cttgagcggg
    29101 aacttctttt ccttctagat aatcatcaat ttcattatat gtgacaccta gtgcgacttc
    29161 atctgcaatc attggtttcc catcttcaag atctgcagtc ggaatttttg tgtataattt
    29221 ttccggtgca ttcaatgctt gaagcaattg tttcccttgt cgtttgtcca aacggaataa
    29281 tggcaaaatg tcggctccac catcaccaaa tttcgtgaag aatccagtaa tgttttctgc
    29341 agcatgatct gtccctaata cggctcctgc tctttctcca gctacggcat attgcgtaat
    29401 catacgttga cgtgctttga tatttccttt gttaaaatcg ctgattccca cacctgcttc
    29461 gcttaatact tgtacttgtg catcaacagc tggtttgata tttactcgca gactaacatc
    29521 gggctggata aagtcaagag cagcttttgc atcttcttca tctgcttgtt caccataagg
    29581 aagacgaaca gcgataaatt gatagttttc atcttttgtt tcttcacgca tttcttccat
    29641 cgttagttgc gccaaacggc ctgctaaagt agaatcttgg ccgccgctga tacctagtac
    29701 aaaagtttta agaaacggat attttttcaa atatgctttc ataaagtcaa tacttttacg
    29761 tatttcttct tttggatcaa ttgttggttt gacacctaat tcattgataa tttctgtctg
    29821 caggctcatt tattctcctc ctatgcttct gtatgaagtt ctgctacgct ttttttcatt
    29881 cgttccatga tagccatttt atggttccag cattcagtag acagatcgac tgggtatttt
    29941 tgcggattca agtctcgttt atactcttcc catagtgaat ctagattttc ttttgtatat
    30001 tctttgattt cgtttagtgc aggtaattcg taaactcttt ttccttcgat aaagatatct
    30061 tgtaaaactg ggcgagctgt aaagtctcga acagttttat tgataaacgt atgcactgga
    30121 tggaacatga agatagcttc ttcttctcga gggtcttcat cccataatgt cacgtagtct
    30181 ccttcagatt tcccatcaaa atttcgagtg atgcgccaca cttgtttttt ccctggagta
    30241 gttacttttt ctgcattgct tgataacttg atcgtatcca tcatttttcc ttcatcatct
    30301 tcgatcgata ctagcttgaa tactgcacca agggctggct gatcataggc tgtgatcaat
    30361 tttgtcccaa caccccatac atcaatttta gctttttgca tctttaaatt caaaatcgtt
    30421 gcttcatcca agtcattcga agcatagatt tttgcttccg taaatccggc tgcatctaat
    30481 tgttcccgaa cacgcttaga tatataggcc atatctccac tgtcgatgcg tacgccttgg
    30541 aagttgattt tgtcacctaa ttctttcgcc acgcgaatcg cacttggcac acctgatttc
    30601 aacgtatcat aagtgtcgac taagaacacg cagtctttat gggttttagc gtaggccata
    30661 aatgcttcat aatcatttcc ataagattgg actaacgaat gagcatgggt cccgctagct
    30721 ggtatcccaa atatcttccc agcacgtaca ttgcttgttg catctgctcc gccgatatat
    30781 gccgctctag ttccccagac tgctgcatcc agttcttgtg cccgtctagt tccaaattcc
    30841 aatagtggat cttctccgat gacagatttg atacgagctg cttttgtcgc gatcaacgtt
    30901 tggaaattga ccatattcaa cagtgctgtt tctactaatt ggcagtgcgc taaaggccct
    30961 tccacttgga ttaatggttc atttgcaaaa actagttctc cttcacgagc agaacgaact
    31021 gttgctttaa attcaaaatt ttgtaaatac tccaaaaaac cttcaggata gacttctaat
    31081 ccacgcaagt aagcaatatc ggaatcattg aacgtcagat tctctaaata attgactaac
    31141 cgttccaatc ctgcaaaaac cgcgtatccg tggttaaaag gcatttctcg aaagtaacat
    31201 tcaaaaacag catgtaaatc agctcgacct aattcccagt atgtctgcat catattgatt
    31261 tgatatagat ccgtatgcag cgtcaaactg tcgtctgggt aagtattatt catcttgtat
    31321 tactcctctt ggcaagtttt catttcctac ccattataac aaaaaaaatt aataggaaaa
    31381 gaaatcttcc attttttctg aaaaagcaca tgttttacgg atatttcttg ctaaaaatga
    31441 actccatctg ctaaaactat cctttcttat tggtatttaa cctaaacgag aaagaatact
    31501 tattttattc aatgtatccg agacacgaag aaattagcgt tttctatttt tcttacttga
    31561 taaaataagt agattttcct actacaatcg tagccgttaa gataccgatg attgaacaaa
    31621 tataaccaaa tgtctctaca acataatcaa tggcaaaagt ttttgaagca ataatacgtc
    31681 tttccttttt tgcttcttat ccccaaagaa acggatataa cttattatgt attgaatttt
    31741 tttggaaagg cgaattatga caagatatac cttgcgttga aaaaactcgc ggaaaaaata
    31801 tcacacgttt ttaaaaagat acaaagtaag aaagcagctg tcaatagaat ggaaacaaaa
    31861 atggcgagac atcaatcagt ctcgccttgt tttttattgt atacattaga tatggagcag
    31921 gttaccataa agatgattat tagtcgttat taaatagaat ccttcgtatt tttttgttct
    31981 atcactacaa tatctttatt tggacgtttg aattgtattc cggcacgttc tagctcctgt
    32041 ttcactccta catggacttt gacatcttct cgtgtcattt ttaaaacgtg atgaatcgca
    32101 tagtcgattt cttgccttgt gatttttttc ttcgtattga tcatcacgac ttgcttttta
    32161 tcatatgtgt ctaccaatag cagttgtgtt cgatctaacg aaaataattt gtaataatta
    32221 atagccgtat tcccaaaaaa gaattccact actttaggat aaaatgtctt aatatttaaa
    32281 ttactattca caggtgtttc gattagcttc atctcattcc tcttttctat atagtcgatt
    32341 tagatccaat cttaagttat gttaccatct ttcctagcat taaggaatcg gttacaattg
    32401 aacctttaaa gacaaaagga tttacctttt atcacttaat agtataacat aatttcgtga
    32461 gaaaaaaata caattttttc ttgaccatct cgttacgtaa aggattatgc ttacatttgt
    32521 caggaggaaa aataatggag tacacaataa agaaaatgtc agagatatca ggagtcagtc
    32581 cgagaacctt gcgcttttat gatgagattg gactgctaaa accagctagg atcaattctt
    32641 caggttatcg gatttatggc aaaaaagaag tcgatcgtct gcaacacatc ttattttatc
    32701 gaacaatggc attcaagttg gatgatatcc aagaggtctt agacaatcca tcttttgacc
    32761 accagaaagc tttaatcaag catcagcaaa tgttgctgga aaaacgggca caaatcgata
    32821 ccctcttgac aactgtccaa cagacacttg atatgtacga aggaggaaga aaaatgagtg
    32881 acaaagaaaa atttgaaggg tttaaacaac aaaagttgaa agaaaatgaa gaatcctatg
    32941 gacaagagat tcgacaaaaa tacggaaaaa aaaaggttac agcatccaat gaaaaatgga
    33001 tgaatatgga taaagaaacg tatgaagaaa tgcaaactgt tgaaaagcag atgttatttg
    33061 atctcactct ttacttaaaa gaaccagaag atgaaagctt agcagaccgt atcttccaag
    33121 ctcataagaa gtggttctct tacagctggc ctgaatatca gccaaaagcg cataaaggac
    33181 taggaatgat gtacgaagcc gatgaacggt tcactgcata ttatgacgag cgaagtggtc
    33241 atggtgcagc aaaagcttta aatgaaatta tccaaaaaaa ggcgtaatct tttacatgat
    33301 ccaacaaaaa agtacacgta aaatgaccta ataacaaaac agcagacacc caagttagat
    33361 ttttatgcta acttttggtg tctgctccat tctttcacaa gttttttcat cctactttaa
    33421 atatattcat cgttgaataa acgtataagg tattttcact ttatcctttt tttctgtaag
    33481 aaacaattga aatgccattt ctccgcaagc ttccagatgg tggtcgatgg ttgggaaacc
    33541 aagaagctcg ctgatcagca aattatcgcg tccaatcacc actggtgtct tatcttgcag
    33601 atagctttgc aagatgcctg ctgcaaccat atccgaattt gtaaagacac catcaactcc
    33661 aagctcttta aaaaagaagc ctgcttgttt tcctttctct gcatctatac aatcccaaaa
    33721 aacaagtgat tcatcaaaag atggaaaaag ttgatgacat agctgcaaag tgatttttga
    33781 gttataactt agcctgccac ttcgccccaa cgtgatgccc aattgcttta taccttgctg
    33841 cttcaaataa gtaagacctt ctgtaattga ttgttctcga tcaataaaga cacagcttgc
    33901 ctgttttccc ttgatttctt cacaaaaaac tagaggtcca tatttttgat atgccaataa
    33961 atcatctagt gtattggcac gagacgtaat gatcaatcca tcgaaagctt tagctgcaaa
    34021 ttcttcaaga taccttcgct ctttttcttt atgatagccc gtcggtaaaa gtgtcacttt
    34081 gtaatcataa tcaaacgctg cttcaatgat cccactgatc aactgatcaa aatacggatg
    34141 attggtataa ggcagaatca ctccaatgct tttcgttttt ccataactta actgtctggc
    34201 atttgcatta gggatataat cgacttcttt catgaccgca agtatttctt tccttttttc
    34261 ctcatctaca tatggatgtc cattgattac acgtgaaata gtagaaactg aataacctgt
    34321 gagctttgcg atatctcgaa tgtttgccac tgctgcttcg ccacctatac aaaaagattt
    34381 tcttgtaaat agtctaccac agctggaccg cattcaaaaa actgatacat ttttccttca
    34441 tgcgaaaaac tgatccgctg cccgccccaa tatatatctt ttgtcaaatt ttcgatttca
    34501 ttcattggta tttcttttac tatattccta ttcaaccctt gaaaactgta caacgttaat
    34561 acggatccct tgaactcgac aaacgcataa aaataattgt tcgttgtgcc atctgttatc
    34621 tctacataag tattcattgc aagccctcct tttgatactt tgagtatagt gtatgaaacg
    34681 cgtctcatag caaggagttt gttttgccaa agaaaagttt tattcctctt tcattattac
    34741 caaagtctct tattttaaat tgaatacatt ataatgatac tgtaaatata tctttattat
    34801 tagtgaatg
//
LOCUS       DAFLVO010000025        34097 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.025, whole genome shotgun sequence.
ACCESSION   DAFLVO010000025 DAFLVO010000000
VERSION     DAFLVO010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34097
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.025"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(29..1261)
                     /locus_tag="L1U99_001247"
     CDS             complement(29..1261)
                     /locus_tag="L1U99_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBN1211798.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1516..2085
                     /locus_tag="L1U99_001248"
     CDS             1516..2085
                     /locus_tag="L1U99_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1211799.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2263..2703)
                     /locus_tag="L1U99_001249"
     CDS             complement(2263..2703)
                     /locus_tag="L1U99_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBN1211800.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2861..3625
                     /gene="map"
                     /locus_tag="L1U99_001250"
     CDS             2861..3625
                     /gene="map"
                     /locus_tag="L1U99_001250"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBN1211801.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3657..4580
                     /locus_tag="L1U99_001251"
     CDS             3657..4580
                     /locus_tag="L1U99_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBN1211802.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(4805..5044)
                     /locus_tag="L1U99_001252"
     CDS             complement(4805..5044)
                     /locus_tag="L1U99_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1211803.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(5049..5468)
                     /locus_tag="L1U99_001253"
     CDS             complement(5049..5468)
                     /locus_tag="L1U99_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1211804.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            complement(5695..6933)
                     /locus_tag="L1U99_001254"
     CDS             complement(5695..6933)
                     /locus_tag="L1U99_001254"
                     /inference="COORDINATES: protein motif:HMM:NF017760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1211805.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            complement(7040..7675)
                     /locus_tag="L1U99_001255"
     CDS             complement(7040..7675)
                     /locus_tag="L1U99_001255"
                     /inference="COORDINATES: protein motif:HMM:NF012655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1211806.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            complement(8017..8652)
                     /locus_tag="L1U99_001256"
     CDS             complement(8017..8652)
                     /locus_tag="L1U99_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1211807.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            9164..10306
                     /locus_tag="L1U99_001257"
     CDS             9164..10306
                     /locus_tag="L1U99_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBN1211808.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            10299..10505
                     /locus_tag="L1U99_001258"
     CDS             10299..10505
                     /locus_tag="L1U99_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBN1211809.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            10584..11777
                     /locus_tag="L1U99_001259"
     CDS             10584..11777
                     /locus_tag="L1U99_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1211810.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            11982..13121
                     /locus_tag="L1U99_001260"
     CDS             11982..13121
                     /locus_tag="L1U99_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HBN1211811.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            13114..13914
                     /locus_tag="L1U99_001261"
     CDS             13114..13914
                     /locus_tag="L1U99_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1211812.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            13914..14741
                     /locus_tag="L1U99_001262"
     CDS             13914..14741
                     /locus_tag="L1U99_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1211813.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            14719..15453
                     /locus_tag="L1U99_001263"
     CDS             14719..15453
                     /locus_tag="L1U99_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBN1211814.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            15553..16419
                     /gene="rfbA"
                     /locus_tag="L1U99_001264"
     CDS             15553..16419
                     /gene="rfbA"
                     /locus_tag="L1U99_001264"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBN1211815.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            16433..17005
                     /gene="rfbC"
                     /locus_tag="L1U99_001265"
     CDS             16433..17005
                     /gene="rfbC"
                     /locus_tag="L1U99_001265"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBN1211816.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            17027..18055
                     /gene="rfbB"
                     /locus_tag="L1U99_001266"
     CDS             17027..18055
                     /gene="rfbB"
                     /locus_tag="L1U99_001266"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBN1211817.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            18153..19004
                     /gene="rfbD"
                     /locus_tag="L1U99_001267"
     CDS             18153..19004
                     /gene="rfbD"
                     /locus_tag="L1U99_001267"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBN1211818.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            19038..21071
                     /locus_tag="L1U99_001268"
     CDS             19038..21071
                     /locus_tag="L1U99_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211819.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            21115..22395
                     /locus_tag="L1U99_001269"
     CDS             21115..22395
                     /locus_tag="L1U99_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HBN1211820.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            22605..23411
                     /locus_tag="L1U99_001270"
     CDS             22605..23411
                     /locus_tag="L1U99_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1211821.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            23423..24643
                     /locus_tag="L1U99_001271"
     CDS             23423..24643
                     /locus_tag="L1U99_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1211822.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            24633..26219
                     /locus_tag="L1U99_001272"
     CDS             24633..26219
                     /locus_tag="L1U99_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBN1211823.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            26258..28396
                     /locus_tag="L1U99_001273"
     CDS             26258..28396
                     /locus_tag="L1U99_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBN1211824.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(28764..29747)
                     /locus_tag="L1U99_001274"
     CDS             complement(28764..29747)
                     /locus_tag="L1U99_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBN1211825.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            30125..31516
                     /locus_tag="L1U99_001275"
     CDS             30125..31516
                     /locus_tag="L1U99_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBN1211826.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            31532..32572
                     /locus_tag="L1U99_001276"
     CDS             31532..32572
                     /locus_tag="L1U99_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBN1211827.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            32591..33676
                     /locus_tag="L1U99_001277"
     CDS             32591..33676
                     /locus_tag="L1U99_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HBN1211828.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            33709..>34097
                     /locus_tag="L1U99_001278"
     CDS             33709..>34097
                     /locus_tag="L1U99_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBN1211829.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKH"
BASE COUNT        11060 a         5833 c         6716 g        10488 t
ORIGIN      
        1 tattttttgc atgtgtgcga aagtatactc aagcccaatc gccatttcgg aaaatcggta
       61 ctgtagagcc atcttcacgg attccgtcga tatccatctt gtcagatcct accatgaaat
      121 ctacgtgggt ttgacttcta ttcaatccag cttctgctaa ttcttcatcg gacatttctg
      181 taccgccttt cacactgaag gcataagcag aacctagtgc taagtgattc gatgcgtttt
      241 catcaaataa tgtattgaaa aagatgatgc cagattgaga aataggtgaa gggtcaggta
      301 caagtgcgac ttctcctaaa cgacgcgcac cttcatctgt atcaagcagt tttgctaaga
      361 catcttctcc ttgttcggca gaaaaatcaa caacttttcc atctttaaaa gtaaatttca
      421 tacccgagat gatggtgcca gcataactca gtggctttgt acttgaaatg taaccatcta
      481 ctcgatgact gtcaggtgct gtgaacactt cttccgtcgg catatttgcc atgaattttt
      541 ctccacgagc attatagctt ccagcgcctt cccaaagatg gtttttaggc aatccgataa
      601 tgatatctgt accgggagca gtatagtgaa gggcagaaaa ttgttctcga ttcaattctt
      661 ctgctttttt tgctaatttt tcatcatgct tcttccatgc taagacaggg tcttcttcat
      721 agacacgagt cgttttgaaa atctgatccc ataatgcctc aacttgtttt tcttctggca
      781 gttctgggaa gacttttgct gcccattgtt taccagccgc agccacgaca gtccaactga
      841 ctttatttgc ttgagttgcc ttgcgtaaat tcattagtgc tttgccattc gctgattgat
      901 aagacgctac tcgatggcta tctacaccag caaatgcatc gggatcggca gaaacaacgc
      961 tgatcctgct tgctcctttt tcaagccatt catccgcttg atcgatttta gattgtggta
     1021 cattctcaat acgatccgtt gcagcatgta aaagaaattc tctttggatc tggtcgtcag
     1081 tccattgaac gataacctca gcggctccta gtttataagc ttcttgtgtg atcaatcgag
     1141 caaggggtgc ctgttccacg ctgatctgta aaacaactgt gtgtcctttt tctgtggcta
     1201 cgccagtttc tgcaattaag cgtgcatatt tttttagaag ttcattaaaa tcagataaca
     1261 taataaaaat tcctcctcac cattttttct ggtaactatt agcatgatac catttaatta
     1321 tgattcaaac aatgaggctt taaataaaaa aaggaggtta tttttttaag gttaagtttc
     1381 atgatatatg ttactacttg ctatttcagc ttgtgaagaa aatcaaaaac taattttgca
     1441 tatcaaaaaa aacatgttac aatgaaatta atcaatggtg gaagcgttat aaaaaaatta
     1501 aggagattaa aaaatatggc aagaaaaaag acgattacta gagaacagat tttggcagct
     1561 gcttatgaag tagctgccac cgatggattt acacgattta ctgcgagaaa catcgcgaac
     1621 aaaatgaatt gttccacgca accgatttat cttgagttta aaaatatgga tgacttgaga
     1681 caagctcttt ttgagcagat ctatgatcat ttacaatatg aagtgttcac tgttgagcat
     1741 acagggaata cgattatcga tcttgctttt aattatatcc attttgcaag aagagagaag
     1801 aagttgtatc gttcactgta cttagaagaa tatggtggag gaaaagagat gcagaatttc
     1861 tcttatactt actttgtgaa tacagtgaaa cgcgatccag cttatgtgaa tctttcagaa
     1921 gagcagatcg aatctttgta taatgggaca tggatcatag ctactgggat cgcagctttg
     1981 atgtcttcaa gcatcatcca tccaactgat gaacagattg aaaagatgat ccaagacagt
     2041 atagatgcta tcttgaaatt caaagaacca atcgaaatcg attgaatata ctcaaaagtt
     2101 ccacaaatca gtaggtaaca agagatgtgt caaaataagg aaaagttcgt ttttcttaca
     2161 gcgtatgcat ttttaactcc cgaagaactc ttccatgaat gcaatgaata aaagagccat
     2221 acagattgaa taaatctgga tggctctttt attgcaagta tattaaattt ttgcgactag
     2281 ttctttagcg aaagcttcta aattttcgat atcttcttct tcagcattca gatccacttt
     2341 aacattttcg gctccttttg atgcgcctgt ttttgcaaaa gcagcatcga aatcatccac
     2401 cgatttgcag aattcatcgt aaaaagtatc accagatccg cagacaccgt aaatttttcc
     2461 caatagatcc aattcttgca agtcttcata aaagtctacg atctcatcag gcagatcgcc
     2521 atcatcgtat gtataagtag ctactacgca aatatctgcc tcctcgaatt catctgcatc
     2581 tacttgggta cattcgttga tttcgacttc gatatccaga ttttcaaatg cttctgcaac
     2641 aatatcggcg atttcttcag tgtttcctgt catgctagca tatacgattt ttgctaaagc
     2701 catgatgtgc ctcctcgttt ataattattt aacaattatg aattatacca aaacatcatt
     2761 gaaaagaaaa taaaacctag agacacctgg ggaatgtcat ttggctaaat gtatgccgct
     2821 atgttaaaat gagagggatt tgtaaaaagg agacgaaaat atgattactt taaaatcagc
     2881 acgtgaaatt gaaatgatgg cagaatctgg agctttatta gcagatgtac ataaaaatct
     2941 gcgtgatttt ataaaaccag gaatcacaag ttgggatatt gaggtatttg tcagaaacta
     3001 tatcgagagt catggcggaa ttgctgcgca aattggcttt gaagggtatg aatatgcgac
     3061 ttgtatcagt ataaatgatg aaatttgtca tggattccct cgtaaaaagc ctttgaaaaa
     3121 cggtgatttg gtaaaagtcg atatgtgtat cgatttgaaa ggcggcattt ctgattcttg
     3181 ttgggcctat gtagttggag aatctacacc tgagatcgac cgattgatgg aagtaacgaa
     3241 gaaagctttg tacatcggta ttgagcaagc acaagtaggg aatcggattg gtgacatcgg
     3301 tcatgctatc caaacttatg tagaaggcga aaatctagcg atcgttcgtg attttattgg
     3361 tcatggcgtt ggtcctacga ttcatgaaga accagcagtt cctcattacg gagaagctgg
     3421 aaaagggttg cggttgaaag aaggcatggt tatcacgatc gaacctatgg ttaataccgg
     3481 aacttggaaa atgaaaatgg atcctaacgg ctggactgcg tatacaagag acggcggact
     3541 ttcttgccaa tatgaacata cattggctat tactaaagat ggtccaagaa ttttgacatc
     3601 acaaggagaa gaaggcactt attgatctat ccagtcaata ggtacgggag aggtacatga
     3661 aagtttggaa caaaataaaa caaaatgaaa atctgatgcg ctttattgag acgactcaaa
     3721 agcgcatcac tgattcagaa atgagtacga cctctgtcgt cgttgcttat tatttactct
     3781 tgtctttatt tccattgatt attgcttttg gtaatatttt accgtttctc cacatcgatc
     3841 aagagactgt actgacctat ttacgagaag tgattcctga gaccgtttac cagtttatcg
     3901 gtcctgcaat caaagacctt ttgacacaaa gttcaggagg cttgttatcc gtttctgcat
     3961 tagcggcttt atggtctgca agtcaaagta tcaatgcttt gcaaattgcg atgaataaag
     4021 cgtatggcgt agaaaataga aaaaattttt tgatcgtccg tttcttctca ctaattgtca
     4081 ttgtcttgtt catgattgct attagtgggg taactatcgt tcttgggttg ggacagctga
     4141 ttttggatgc tattcagcca atcgtacaaa tacccgtgaa ctttatcgat cagttccaaa
     4201 ctttgaagtg gccaatcaca ttggtagctt tatttgtcat catgttcttg atttatttaa
     4261 ttgtccctaa tgctcagttg aagttgaaga cgatcattcc gggcacgatc ttcgctactg
     4321 tcggctggat gctgttatca caagtgttta gtatctatgc taggtatttt gcaacgagga
     4381 tcagcggtta tcagatcata ggaagtttta ttgtactcat gctttggctt aattttgctg
     4441 ctacgatcat cattttgggc ggaatcatca atgcagttgt tcaagaatac gtgacgggtc
     4501 atcaaatcaa aaaacgtcga gatccaagcc gaaaatggtt caataaattg aaaactaaat
     4561 tttctcataa aaaaaagtag aaacaagagt tcttattgta aatttatatc agtaatttat
     4621 ttgaaatttt atatctaatt ttcaattatc cgcataaaca ctatacattc aagcattttg
     4681 aagtatagaa aaacactcat cttaccacga atttaccacg attgaatgag ccttgatatg
     4741 accgtaaaac tactaaggga gatagcacga aactgtgtat ctcccgattt ttttatacag
     4801 ttgattactt cactccgatt tcaaatttca atattgcttt catcatgtct gtatgaattt
     4861 ctccttttag ttcttcatca acctgcataa tgattttacc actttcagag tggtaaaaag
     4921 gacgcaagca taatttagaa atataaccgt cataaaactt caaaatctct ttaactgcca
     4981 tttcatctcc gcttgacgct ttgcaaatca attcaaaaga gggatagcca taatctttac
     5041 tcatttcttt acttcctttc gctcaaaagc atttttaact tccttagtcc tctagttctt
     5101 ctactgcaaa tagcagaacg tgatacatgg tacagttctg aaatttctct gtcgttcatt
     5161 ccttgaaaat aacgtaataa aatcgcacta cgctgttttt ctgacagtct atgtaaaact
     5221 gtaccaagtg tttcatcaga tacataaatt gtaaagtgca agactttaaa tgatacacaa
     5281 tcataaaaac aggtatcaat cgttccacgt tcaacttgtt tcgtttcggc tatttcacaa
     5341 aacaatactt cacgtttaga atgtcttgca agctgtctgt ttcgactttt cactttgttc
     5401 ttaatgacaa tcagcattaa agaattgaac tgtaatctga cgatatgctc gaaagaagat
     5461 gtcctcataa tctcaccccc tttctgctaa tgctgaaata tataaacgga ataccgttta
     5521 taccctttag aaatacagaa aaatggtaag aaaaaagccc acacaaaaca tatatttgtg
     5581 cgagccttaa atactgcaat attactcttt cttttataac actatccttt tagcagattt
     5641 caaattttct tttatatatt gtttttagcc taacatacta tttaacccct tgtattatat
     5701 ctctaacttt tgaaaaattc tttttgaata tattgaaatc atgattgaag caatagaagc
     5761 tacaaacata acaacccatg tttcttgtat aaatacatcg aataaaatac cgtaaaccat
     5821 ttgtccaata ggttgaccgc acatagcaac tgctaccagc gtagccatta tctttcctac
     5881 taattgcggt ggtgtttgtg tctgaacaag agtgtaaatt tgaacaacaa acatagtaga
     5941 tacacccata gccacaaagc acatcactgt aactacccag taggaaacta ttgcaggcaa
     6001 ttctaaaaat agcgaaattc ccataagtaa aacagaaaca gaacaaataa gtaacaaggt
     6061 ataaaggttt tttagtttta actttgaagc aacaagagct gttaaaatac caccacataa
     6121 accacctaat gataatgctg attgtgaaaa accatatagt gtatctggca tttttaaaac
     6181 ttcagaaatt aagataggca gaccaacaat taaaacagca cttaaaacca aattgaaaat
     6241 gcaaaccaaa aagattacgg atataaaaat gggtttctcc tttttcaaaa aggtataact
     6301 atcttttaaa tcgtttttag caactgcaat tacacctact tcacgaggtc ttttttggtg
     6361 tggaatatgg ataaaaattt ccataatggc tgaaaaagta aaacatataa tactaacaat
     6421 taaaatggga ttgataccat aaaattgaaa aactactccg cttatagctg gtccgataaa
     6481 gtttgctaaa gtatttactt gatttattat agcattaccg acggtaagtt tatctgatga
     6541 taccaataga ggaatacttg cttgtaccgc tggttgatat gcaccagaaa taccataaag
     6601 taacatcaaa gcaacaataa acaaaggtat gataggaatt tttcccaatg acaaataaaa
     6661 tactaaaatt atgattgctg ttacaaaatc tagtatgacc ataatgtttc ttttatttgt
     6721 cctgtcagca ataataccac ctaccagcga caaaataacc ataggtaaaa aagagcaggc
     6781 tgtagcaata ccaaacaaag ctgatgaacc agtttctttt aacaaatagt acggtaatgc
     6841 aaatcgtagg atagcgtttc caaataaaga aattatctgt cctataacaa caagtataaa
     6901 atcacgatta aaaagttttt tttctgcttg cataaaatct ctccttttta tttaatcaaa
     6961 cagaccgtcg gtttatataa tggtttaaat aaactgctct tttatagagc agtctatcgt
     7021 atagggataa caaatacagt tatttacaaa actgtataaa tgcagaaatt gtttcttcgt
     7081 ctaataatgt gtctatgcct attccattta aaagggcatt gaatgtattg caacgttttt
     7141 ccataccctc tttatccgtc atttcaacta atgggttgag ccatacatta cttaatacca
     7201 tgataacttc tgcaatttca tgtgaatttt caatctccaa agacttatcc ttgatacctt
     7261 gttctaaaac gggttcaaca aattcaggta ctacaatttc atacatttgt tctatttgca
     7321 tagcaagaaa acgaggattg tttaatagtt gaggagaaac tgtcaataaa acgctttggt
     7381 tagaattgaa taccgctgtc ttaaatattt ctcttaactt ttctaaaccg tttaaactat
     7441 cgttatctct aattttagca aatattactg cattttcatt tccaattctt tgaaaaattg
     7501 cttttaaaat atcttccttt gaatcgaaat gatgataaat agcaccttta gaaagttttg
     7561 tttcattgat aatatcttgc aatgatgtgt tatcatatcc tttttcacaa aacatttttg
     7621 tagaaacatc taaaatgagt tttactgttt cttctggata tttatttcgt gccataactt
     7681 acctccaata caaaccgttg gtctgattaa agtatatctt agtattttat gcttgtcaat
     7741 ataaagactt gcaattttat aaaaatgcag aatgcaagcc tttttcattt attctacaat
     7801 cttccagttg ctttccttat gcggtgtcaa ttcatactgt gatacctgcg ttgcctttgc
     7861 ctgatttacc acaaatcaga ttttatccct ttcttcctct tgattgccca caacagaaaa
     7921 gaaaaagccc tgtcaagagc tttgccacca ttggtggtgc tttgcactct tgatcgggct
     7981 ttttgtttgc tgtatcttct cgcaagagga aaaaagttac tcgtcctcat catcaaaatt
     8041 gttattcctt aatacttctc gtaacagttc catatcttct tttgagttcg ggtttatcat
     8101 tttcacgact tgataaggtg tcttatactt atgtccctct atgctttccc caaacatatc
     8161 catactgtat aaatcatcat agcggtctaa taatttttga aacttcaaat gctggataaa
     8221 ttctttgatt gggtaaaggt cggacgcttc aatgcttttc ccgttgatat agtctgtaat
     8281 atattcccgt aacttttcta actcatattc cagccattct tcctcgctgt caaagaagtt
     8341 atcatagtgt ccatgtttca gttctgcatt tagacgttct tcggctctta aaaactgaca
     8401 gacttccttt tcagattgat tgacatactt ccattctccc gacaacaatt cattgggcgt
     8461 aacgtccagc acttccatta tcttttccag cgtttcatag gcaggatagt tcaaccctct
     8521 ttcaatcttg gaaaggctct gcatattgat accgattttg tccgcaagtt cctgttgttt
     8581 cattccccta aattttctta tggtctgtat attatttcct aaatggctta ttttcattgc
     8641 ataaccctcc atatctcgtt atatcttcgc tattataagt ctatcatgct taatatgatt
     8701 tgtaaaggca aaaaaagata ttgacaaata agcatataag aattactatg ttcttgtaat
     8761 cgaataagca caatagaatg aaatataaaa acattcaaaa agaaatacct atctgattaa
     8821 atccgtagat atgaatatcg gttgaaatgg aacttgttag aaaaggcaaa acagaacttg
     8881 ctgacaaagt atttctgaca cggtggcgga agcctctcag gcttaccgcc atgacacctt
     8941 gtgtcaaggg gaagaaatgc tttgtcggct ggcgagcctg cgagccttgt ctgtgccccc
     9001 gttatctaac aggggggcac tatttcacaa aagacaagtc aaaaaccata cacccccaaa
     9061 cctgtgagta gtaatgagag gttttaagaa gatagtacat atcacacttt ttgaaaggtg
     9121 gtttacaggt atttcaaggc tattgtggga ttggaggaat acaatgaaca atttagaatt
     9181 tgcacttgaa atgaagaaca aacgtcttgc cagcggtctt tcacaaggag aacttgcaag
     9241 tcttacccat gtatcaagat atagtatcaa ccgctttgag aacggaaaag ctaacgccag
     9301 caaggaaaca cagaacatta tcctgcgttg tctgaattac tatatctgcg ataagccttt
     9361 ttatctgctc gttgattatc tgtctgtccg ttttccaacg actgacgcat tggaagttat
     9421 ccgaaaggtg cttggcatga aagcagatta ttttatccat tatgactatg ggtattatgg
     9481 ctataaggag cattatgctt acggggaaat caaggtcatg gcttctgatg atgaacacat
     9541 gggcgtattt ttagaattaa aaggggcagg ctcacgcaac atggaatatg tcttacaggc
     9601 acagaacagg gactggtatt cattcttaaa ccgctgtctt gactgtggcg gtgttatccg
     9661 acgttttgac ttggcaatca atgatatgtg cggtctgctg gatattcctg tgctatctga
     9721 aaaatacaga aatggtggtg cggaatgtcg ctgtaaaaac tatgaaaatg tacaaggtgg
     9781 aaaattaagc ggaaaaaacc gtaatttagc aagtaccctt tatatcggct caaaggcaag
     9841 cacaaaatat ttctgcctgt atgaaaaaca aaaggaacag gcaacgaaaa agaaacatac
     9901 cgatattatc aaccgttttg aaattcgtct gcgtgacaaa aaggcggtac aggcagttga
     9961 agaactgtta ttgacgtata accctcatgg gctggtgttt tatctcatta ccgattttgt
    10021 ggaatttcct gactatccat tgtgggagat attcatttcc catgacagtt taccttttga
    10081 aatgaaccct gtacctgtca atatggaacg cactctgcaa tggctggaaa gacaggtcat
    10141 gccgtcaatc gtgatgatag aggaaatcga caggctgaca ggttcaaact acatgaaaat
    10201 gattgatgaa tgtacccacc tttctgaaaa acaggaaatg cttgtggaac agatgtgtac
    10261 ggacatatca gacgtaatcg aaagtgaggg ggtgttttat gagtaataca caggatattc
    10321 ccgtatggga aaaatacacc cttaccattg aagaagcgtc aaagtatttc cgcattggag
    10381 aaaacaagtt aagacgattg gcagaggaaa acaaggacgc tggctggctc attatgaatg
    10441 gcaaccgcat acagattaaa cgccgacagt ttgaaaaggt tattgataaa ttggacgcaa
    10501 tctaatgcaa atgagccttg tatgtgttat gatgaacaca agtcatatca aggctctttc
    10561 caacaaggaa aggagcagac accatgaaag aaaaaagacg ggataacaaa ggtcgtatcc
    10621 tgcatactgg agagagccaa cgaacagacg gaaaatactt atataaatat gtagacgcat
    10681 tgggaaacac aaaatatgtg tatgcttgga gattgacacc cacagacccg acaccaaagg
    10741 gaaaacggga aaaaccctca cttcgagaac tggaacagca gataagacgg gatattgagg
    10801 acggtatcga cagcacaggc aagaaaatga cgctttgcca actctatgcc aaacagaacg
    10861 cacagaggac aaatgtgaag aaaagcacac agaaacaacg ggaacaactc atgcggttat
    10921 taaaagagga caagttaggt gctaggagca ttgatacgat aaaaccctct gacgctaaag
    10981 aatgggcgtt acgcatgaaa gacaaaggct tttcctacaa taccattaac aaccataaac
    11041 gctcgttaaa agcgtcattc tacatagcca tacaagatga ttatgtgagg aaaaaccctt
    11101 ttgatttcaa gctaagtgaa gtcatagaaa atgataccaa agagaaagtc gcattgacag
    11161 aggaacagga gcaagcctta ttgtcattta ttaagacgga caacgtgtat cacaagcatt
    11221 atgatgatgt gctgatactg ttaaagacag gacttcgtat ctcggaactg tgcggactga
    11281 cagtagccga cattgatttc aagaatgaag ttgtgattat cgaccaccag ttactaaaga
    11341 gtaaggaaca gggctattat attgaaacgc ctaagacgaa aagcgggata aggcaagtgc
    11401 cattaagcaa agaaacgata caggcatttc aacgggttat caacagccga ccaaagataa
    11461 agtcgataga ggtagacgga cacagcggtt ttgtgtttat caatccgaaa ggtaatccaa
    11521 aagttgccat tgattataac gccttattta tccgtatggt aaagaaatac aacaagcacc
    11581 acaaggacaa tcccttgcca catattacac cgcatacgct acgccataca ttctgcacaa
    11641 ggctggcaag caagaacatg aacccgaaag atttacagta tatcatgggg cattcaaaca
    11701 tcagtatcac aatgaactgg tacgctcatg cgtccataga taccgcaaaa tcagaggttc
    11761 agcgtctaat cgcatagaag tatttaccac gattttaacc acgattgaca gggaaaatat
    11821 aagaagatag acctagatat gcgaggttta ccacaaaagc aaaatgcccg tagagccgat
    11881 aaaataaggc tttgcggaca tttgagaaga tataaaaaga tagtcaaaaa gacatatata
    11941 atttataata attatgactc ttaattaaag taggtgccca tatgcttgtt tcttttagta
    12001 tggttataag attttttctg acaattttat tatcactgat attaacacct gtattcaaaa
    12061 tcatttcagt acaaacaggt atggtcgaca aaccaaatga aagaagaata aataaagttc
    12121 caatgccttc agcgggcgga ctgcctatct ttatttcatt tgttatatcg actttattct
    12181 tattccgtaa aattatccct caatcgtata ttgtaccgat cttgattgct tctttagtaa
    12241 tcatagtcac aggagtgctc gatgataaat atgagctgac acctaaacaa aaaagtatag
    12301 ggatcttgat tgcttctctt attatttatt ttgtagcaga tatacgtatt gattccttca
    12361 cgcttccttt tattggatat atccaactag gctggcttag ttttcccgta acgatttttt
    12421 ggatcttcgg tatcacgaat gcggtcaatc tgattgacgg tttggatggg ctggcggcag
    12481 ggatttcatt gatcggttta attacgatag gaatcattgg atattttttc ctccatgctt
    12541 ctacagtgta tattccagtt gttattttct gtcttgtagc aagtattatc ggtttttttc
    12601 cttacaattt ttatccggca aagatttatt taggcgatac aggagctcta ttcctagggt
    12661 ttatgatggc cgtcctttca ctacaagggc tgaagaacgt gacttttgtt tcatcgattt
    12721 ctttgctgat cgtcatggga gtgccggtaa cagacacgtt ttttgctatc attaggagaa
    12781 aagcaaaccg tgtttctttt tctacagcag ataaaaaaca tcttcatcac cgactaatca
    12841 gtttaggctt tactcataaa ggtgctgtcc tgacgattta tgcgatggct ttgatgtttt
    12901 ctttcacagc tatggtcatg aattatactg gaagaatcgg aacgatcata ttgattattg
    12961 ccatgttgtt tgctgcaatt ttattatttg aattgattgg tctgatcaat gagaaacatc
    13021 agtttatttt aaaaacattg cgatttttag ggaataaaga gtaccgtacg caagtaaaac
    13081 agaaatattt gaagaaatgg aaccgtcata tagatgaata acaaattaaa ccagccgatc
    13141 cttattagta ttgtgacggc aaacagtgat aaaatttttc ggacactaga taattttatt
    13201 tcaactgtaa aagatgaaac agcagtaaaa atccgaattt ttgacaacaa ttcacttccc
    13261 gagtacaaaa aaagactaac agagtatagg aaatatccct acatcgatat ctattttcat
    13321 gatgaaaatt ccggatttgg ttatggacat aatcacaatc tgatagctag cgattctcgc
    13381 tatggcatta tttgtaaccc agatatttta gtggatgaag agacagttac agcattggtc
    13441 ttgttattga aagaacatcc ggaatgtgcg atgttagcac ctaagattct taatgaagat
    13501 ggaacaactc agcacctcat ccgtgagcag ctggctgttt ttgattacgt tttgcgcttt
    13561 gtgcctttca aatgggtcaa aaaaaagttt gacaaacgac tggctgtgtt tgaatgccga
    13621 ggattgccta ctgatgctaa tagttatgta cggatgatct caggtagttt tatggtagct
    13681 gatattgata aatttaaaga gataaagggg tttgatgagc gtttcttcat gtactttgaa
    13741 gacaacgact tgtgtttgag ttttgaaaaa gcaggttaca agttattgta cacacccttt
    13801 tatgcagtta tccattttta cgggaagggt gcgcatcgaa atgcaaaact gtttcgcgtg
    13861 tttttgactt ctatgatgaa atttttcaat aagtgggggt ggcgtttttt ctgatgaaac
    13921 cagaaatatt agtagtcgtt gtgctttatc agcaactatt cagtcaatct ccagcttatg
    13981 gaccattaag caaagcactt agcgaaaagc aaattcagct tattatttac gataatagtc
    14041 ctcaaaggca gcaaaatgag ctgtttgaaa aagaaaatat cgtttatcat catgatccgc
    14101 aaaatcctgg tttagcggtg gcttataatt ttgcgttgtc tcaagcagat gaaggaacac
    14161 gttgtctcgt cactctggat caggatacga ggctagtcga cgattatttt gaactattgc
    14221 gtaaagtaac ctttacagat gaatgtgttg ctgcagttcc gatgattttt tctgggagcc
    14281 gacaagtttc tcccctatat tcagatcgtt atatcaatcg tacagctcaa gcagtagaag
    14341 ttgaaggccc aacagctgaa cgaatcatgg caatcaattc aggtgttgcc tggtctgtca
    14401 aatttctaaa aaagattggc gggtttaatc ctgctttttc tttagatttt ttggatcatt
    14461 ggctgttttg gaaagtggat cagttggaaa aaactgtgga gatccttcct gtacgaatgg
    14521 aacatgatct ttcggtttta gactatgaaa aagtttcaag taatcgatac cgttctattt
    14581 tacaagcaga aaatcgattt tatcatgaat atgatcaaag gcatttatcc agtcaccgac
    14641 gacaattatt gttaagaaca gctaaacagt tcttgaccgt caaaaaccgg catatctggc
    14701 ggatgacttt gcgctcatat gttaagaatt ggaaggtgtg aattcgtgcg ttcggtttgt
    14761 atagctacct ttaatggagg cagatattta agagagcagt tagatagtat tttatctcag
    14821 ctttcagcag aagatgaagt agtcatttct gatgatgggt cagtagatga tacatgggat
    14881 atattaactg aatacgcaga aaaagataag cgaatccagc ttttttcggg gcctcgtcaa
    14941 ggattgatcg ctaattttgg ttatgcgatc cagcagacga aaggagatct aatctttttg
    15001 gcagaccaag atgatgtttg gttggagaca aaagtgaaaa agatcactga ctattttgag
    15061 cagaatccgg atcagctagt agtagtttct gatttaatca ttgtggacag cgagctgcaa
    15121 gagatccatg attcgtattt ttcgtttcga aattccaaag aaggatggct taataatgtg
    15181 ataagaagtc actatattgg tgctggtatg gctttccggt cttctttaaa acccgatatt
    15241 ttgccgatcc cgtcagaagt gccgatgcat gatatgtgga ttggtttgct gggaggaaag
    15301 aagactgggt tcctaagaga accgttaact ctgtaccgaa gacatgattt aaacgcgagt
    15361 gagattgaaa cacattctaa attacggcaa aaaatttctt ggcgtgttca tctgattacg
    15421 gcgttgatca aacgaaaatg gtttaaacgt tgataaaaga tgtttaaatc cttaatattt
    15481 ccatgacaaa tataacaatt gatgagataa taacaaagtg aaatttgaaa tcaaaaagga
    15541 gagcagatat ccatgaaggg aatcattctt gctgggggca gcggaacacg tctgtaccct
    15601 ttaacaaagg caacatcgaa acaattgatg ccgatttatg acaaaccaat gatttattat
    15661 ccaatgtcta ctctgatgtt ggcgggaatc aaagaaattc tgattatttc aacgccacaa
    15721 gatacaccac gtttcaagga attatttgga aacggaaatg atttaggact gcagatcgaa
    15781 tatgcagtac aagaaagtcc agatggattg gcacaagcgt ttatcattgg agaagaattt
    15841 attggagatg atagtgtctg cttggtatta ggggacaata tttactatgg tggcggtctg
    15901 tctaaaatgt tgcaacgagc agcttcaaaa gatacaggcg cgacagtatt tggctatcat
    15961 gtcaatgatc cagaacgctt tggtgtagta gaatttgatg agaatatgca agctttgtcg
    16021 attgaagaaa agcctgctca gccaaaatca aattacgctg taactggcct ttatttttat
    16081 gacaatgagg taatttctat cgctaaaggt atcaaacctt cagaacgtgg agaactagag
    16141 attacggatg tcaataaagc atatttggat aaaggaaaac tatccgtaga acttatggga
    16201 cgcggatttg cttggcttga tacaggaaca catgaatcat tgcttgaagc atctaccttt
    16261 atcgaaacaa ttgaaaaacg tcagaactta aaagtggctt gtttggaaga aattgcttac
    16321 cgtatgggct acatcgataa ggaacaattg ctggcccttg cacagccatt gaaaaaaaat
    16381 caatacggtc aatatttatt gaatttggcc gctgaataag gagtccttac agatgaaagt
    16441 aacagataca aaattaacag atgtcaaaat cgtagaaatg gacgtctttg gcgatcatcg
    16501 cggtttcttc acagaaagtt attcaaaagc aaaatttgca gaacatggat tgaaatatga
    16561 ctttgttcaa gacaaccatt cactatcagc tgaagctggt gtccttcggg ggcttcattt
    16621 ccaaaaagga gaagctgcac agacaaaatt gattcgggta gtcactggag cagttttaga
    16681 tgtagtagtg gatatccgca aaggtagccc gacttatggt caatgggacg gatttatctt
    16741 atctgaacat aatcatcgac agttgcttgt acctaaagga tatgcccatg gattcgttac
    16801 tttgacacca aatgtgaact tcctttataa gtgtgataat tactataatg cagaagcaga
    16861 tgggggcatc gcatttgatg atccagattt agcgattgat tggccaattg atccatcaag
    16921 agcgattatg tcggaaaaag atcaccgtca tccgacatta aaagaatttg aagcagaaaa
    16981 tccatttgtt tacggagaaa tctaagaatt aaggagaaat tttcttatga aaaacatcat
    17041 tgttaccgga ggtgccggat tcatcggctc taatttcgtt cattacgtgg taaacaatca
    17101 tccagaagtg catgtcactg ttttggataa actgacttat gcaggaaaca aagagaactt
    17161 ggctggactt cctagcgatc gcgtagaatt ggtcgtagga gatgttgcag atgcagaatt
    17221 agtggaccgt ctagtaaaag aagcggacgc agttgttcat tacgcggcag aatcccataa
    17281 cgataattca ttaaaagatc ctttcccatt tgtacaaacg aatatcattg gtacgtatac
    17341 acttttagaa gcttgccgca agtatgatgt acgctatcat cacgtatcta ctgacgaggt
    17401 ttacggcgat cttccattac gtgaagacct gccaggacat ggggaaggcg aaggagaaaa
    17461 attcactgcg gaaacaccat ataatccttc aagtccatat tcttctacaa aagctggttc
    17521 agatctgtta gtaaaagcat gggtgcgttc ttttggctta cgtgcaacca tttcaaactg
    17581 ttcaaacaac tatggtcctt atcagcatat tgaaaaattt attcctcgcc aagtaacgaa
    17641 tatcttaagc ggtattcgtc caaaattata tggcgaagga aagaatgttc gtgactggat
    17701 ccatacgaat gatcattctt cagcagtgtg gctgattttg acgaaaggca gaattggcga
    17761 aacctatctg atcggtgcag acggtgaaga agataataag accgtgatgg aattgatctt
    17821 agaaatgatg ggtcaaccaa aagatgcgta cgaccatgta aacgaccgtg caggacacga
    17881 cttgcgttat gcaatcgatt cgacaaaatt acgggaagag ttaggatgga agcctgagtt
    17941 tacgaacttc cgtgatgggt tggctgacac gatcaaatgg tacgaagaac atgaagactg
    18001 gtggaaaaaa gaaaaagagg ccgttgaagc agcatatgcc aaaaatggac aataatacag
    18061 agaaaatgtc actgtattaa tggaaaaaca catgtgaggc aggcgctcgc ctgtctcttt
    18121 tttaaaataa aaatcaagga gcggataatc atatgttttt attaactgga ggaaatgggc
    18181 aactaggtac agaattgcgc catttattag atgaaaaaaa tctgcaatat gtttcaacag
    18241 atgcaaaaga cttggatatc acagatgccg agaaaacaat ggcttacatc acagaattaa
    18301 aacctgatgt tattttccat tgtgcagctt acacagcagt agataaagca gaagaagaag
    18361 caaaagaatt agatgagaag atcaatgttg atggtacaag aaatgtagca cttgcagcaa
    18421 aagctgtgaa tgctcaattc gtctatatca gtacagacta tgttttcgat ggaaaaaaca
    18481 aaaatgtaga atacgaagta gacgaccaaa cgaatccact aaatgaatat ggtcgtacga
    18541 aattattagg cgaaaaagca gtagaagaga ttttagaaga ctattatatc atacgaactt
    18601 cttgggtttt cgggatctat ggacacaatt tcgtcttcac gatgcaacgc ctagcggaaa
    18661 cccgcgacaa actgactgta gtaaatgacc agtttgggcg accaacttgg acacgtactt
    18721 tggcagaatt tatggtatat gtcatcgaag aaaaagcacc atttggtatt tatcatttgt
    18781 cgaacgaaaa tagctgttct tggtatgaat tcgcaaaaga aatattgaaa gatacagatg
    18841 tagaagttgc acctgttacg tcagaagaat ttccgcaaaa agcaacacgt ccgcagtatt
    18901 cagtcatgag cctgaaaaag acagaagagt taggatttgt cataccaact tggcaagaag
    18961 cacttgcgca aatgctggaa gctgccaaaa aaatgaataa gtaatttcct tttatcaaat
    19021 agaatttgga gcatgatatg gaaaaacaaa caagaagtgc acgacgaaaa gaaaagccaa
    19081 aagcgaacca ggcagattcg aatttggtgc ttgacctgtt tctaaaactc cgctatctta
    19141 ttggcgtttt agtcatcgtg gtcatcgtta cttttaattt aaacggaagt tcacttggtg
    19201 tttgggataa atatgtgtcg caaagagacg atgggaaaaa aactgatgtg atttttggac
    19261 agaatcggga agtgcggtca gacgaatggc tggtgcagac acctttttac ctctcacaag
    19321 ctgaagagga ctttccgttg gtgaacgagg attattcatt aaacggacaa aacatgatca
    19381 ttgcgtataa ttctcctgta aaggatatta cggttatcgg aaaaccattc aactggggat
    19441 tctttttcct cggaagagat cgaggacttt ccttttattg ggcgatgaaa ttagtcgtca
    19501 tggtcttgct tggattcgaa gtactgatga tattaacgaa gagaaaaaaa gctctatcgc
    19561 taatcggtgc atttgcgctg acattttctc cagcagtcca gtggtggttc atgcaacatg
    19621 tgggcgattt gattttcttt actttgggac tgatgactgc tttttatcat tatttctaca
    19681 atcatgataa aaaatggcta cgaacgttga tgatgctttt ggtggttatt ttcggtattg
    19741 ggtttatttt agtgatttac ccagcccatc aagtgatgct ggcgtacttg ctgatttttt
    19801 attttgttgg cctgcttatt tactatagca agaaagtttc atgggatctg ttggatgtag
    19861 tgttgattgg aggggcagtt ttatttattg gcggagtcat ggttcatttc tggctaacgt
    19921 caaaagacgc attgttagct tctttgaata ccttatatcc aggaaaacgg gtaagtactg
    19981 gaggaaagtg gacgattggc gaattttttt ctttccttac aaattggaaa attccttttg
    20041 aagatatcaa ctattcgaat aactctgaag tggccctgtt ctatcacttt tttccaactg
    20101 tattcctagc aagtccattt gtgttatttg gcaaaaaaga tagcgaacaa aagttactgg
    20161 gacgtatttt gatgattttt tgtctgtttt ctatcttttg gattaccgtt gggttgccaa
    20221 aatggctagc agaaatcact ctgctgtctt atgttcctcc attaagagcc atccttactt
    20281 ttagttttgc ggcttgttta ttatcgatct ggtttatcgc ttatatttgg agagaagatg
    20341 ttattcctat ttggtataaa ttcattttgt tggcagtaaa tgcatggtct tatttctatg
    20401 cgattacgca ttcgaaaatg gataattatt tttcggattt tgaaaccatc gcagttgctg
    20461 tgttgggaac agtgatttta gcttttgcat tatttggctg gagacgcttg ttttacctcg
    20521 cttttgccgc cttagttatc gtatctggct ttttcgtcaa tccagtcgta gaaggtacag
    20581 gagcgatttt tgaaaaaaca ctggcaaaag aaatccaaaa aatcgatcaa caagatcctg
    20641 gtaaagtttg gttgtctgaa gatgaattat ataacttcac cccaacattg ggagtgaaat
    20701 ccttcaatac agtacgcttt tatccagata tagctgcatg gaagaaaatc gatccgaaag
    20761 aagaatacga gaagtattat aatcggtatg ctcatacaag agcttttatc gctaaggaag
    20821 atacaaagtt cattttagat cgtccagata tgttttcggt cacgttgaat tttgaagacg
    20881 cagaaaaatt agggatcgac tatgtgatca gtaaacgacc attaactgat tacaaccaat
    20941 tatatgaagc gcagttcacg cagctatatg gaccggataa agacggttat atgattttta
    21001 aagtagaata tccggattat ccagatgtac cacaaacaca aactcaggaa aatcagctag
    21061 tcgtacagta ataggctagc tgagaataat cctgaaatgt tagtagaaag gagagtggag
    21121 ataattcaag caatcgtaca aaaatttgtc aacaaaatga gtgtcggttt cttgcttttg
    21181 ttactgacgc tagtcttttt tgtttggaca gcagggttag gttttccagc aactttgttt
    21241 atatataaca atagttcatt acttatcgct tttagtgtgg ctattttgct cattttaaat
    21301 gtttataaag caaaaggcgt cgattttctt tatctaggtg ttgcgcttgc ccttttcatt
    21361 ttcttttctt actttcggga attaagaaat gagtctttat ttggagactt actgtttcct
    21421 ttgattattt tattttgttt agtaattaaa tggatcgagt ggacaaaatg ggatcgcggt
    21481 atttatctga ttgtcttttc ggtcttcctc ggaatcacgt tatatcgtgt atttacagag
    21541 atccaagtac cagaaggaca aagcatctgg gctccaggca attcgctttc tgatatttgg
    21601 atcaatacga atataatcgg aagttctttg atgactcttg ctttattgat cagtggattt
    21661 gccagttctt ttgaacgatg gtatgtacga atcatcggtg cagtagcagt tgttgcagct
    21721 tttctcggga tttgggtctg ccaatctaga ggtgcattag tcgcgttgat tgtttttgcg
    21781 atattggatc ttttacctaa atcgttgatg cgtgtcattc gtgcgccatt tattgcttac
    21841 acggttacga ttcttttagc tttgccgatt tcttatctgg cggctgtctc tgaaaaagtc
    21901 aatttgttta ccggtcgaga agatatttgg cataaattct atcagacgct aggagaaaaa
    21961 tctgaacaaa ttttactagg aatgaaaaca tttatcttcc aacgaggaaa ccaattttta
    22021 ggaaaccaca atagttataa ttctattttg aatatctatg gattgatagg atttgggatt
    22081 gctgctttgc tgcttatcct ttttattggt cgcttaacgt tgaaagcaga tttatccaac
    22141 gggcagatga cttttatctg ggcctttttt gcggtgatga tgcagtcatt tatggaggat
    22201 acattgactt catacccatg ggttccgatt atttatatcc tgttggctat ggccgttcat
    22261 cgatatgatg aaccagaagt tgcggaggaa ttctatgtta tggaagaggc atatgacgat
    22321 atgacttatg atgatacatc ttatgaggaa caaccagata gcgctcattc ttccaggatc
    22381 caacgctatc attgataggc acaaaatacg agagaggctg tgacaaccgt cgcagccttt
    22441 tttggtttat tgcaattgtc tagcatcttc tgtaaaatag aaacgttaga gaaaatcttg
    22501 tatcatagaa aattaagaaa gaaataagaa cgcagctcgg taccaaaaat atggtaaaat
    22561 ggcacttgac tgtaattcac tgaaaatcgc ttggaggaac acaaatgttt aaagatttgt
    22621 atttatttat gaaggacatt tatcagaaca gaaaattatt gctacagttt tcgatcaatg
    22681 acttcaaatc aagatatgca ggatcgtttt taggaatctt atgggcgttt atcaatccgc
    22741 tatttactgt attgatttat tggctggtat ttggtgttgg actgaaagca caaatgatcg
    22801 atgcaaaata cccatttatc gtatatttag ttaccgggat gattccctgg ttcttcttct
    22861 cagatgcatt tgcatcaact acggttgttt ttcgggaata tacttattta gtaaagaaag
    22921 tcgtattcaa tattcgtatc ttgcccacga cgaaaatcct atccaatctg tacacccact
    22981 tattcttcat tctgattggc atagctgtcg cgcttataaa tggtatatat ccttcagcaa
    23041 tgtctttaca gctgatttat tatttatttt gcatgtgtgc tttcttgaca ggattgactt
    23101 ggctgacggc atcgatccaa ccatttttac ctgatatcat gcaattaatt acgatcgtgc
    23161 tgcagttgat catgtggaca ttaccgatat tatggagccc taatcagttt gattcaggtc
    23221 ttgtaagcat attgaaatta aatccgctgt actatgttgt tcaaggttat cgtgagtcat
    23281 ttttaagtga agcttggttc tgggagcatg gaacatatac tttgtatttc tgggttttca
    23341 cgttagtaat gttcgtaatc ggctctgcag tgttccgtag attgaaacca catttttcag
    23401 atgtgctgta aggagaatag ctatgacaga atatgcaatt agactaaaag atatcacaaa
    23461 atcttataat atgtacgcaa aaccttcgga tcgatttcgt gaagccctca atccttttaa
    23521 gaaatcctat catgatgtat tttatgcgtt gaaaaacgtg aatgtagaaa taaaaaaagg
    23581 tgagatgatc ggtttcgtgg gagaaaacgg atcgggaaaa tctacaatgt tgaaaatcat
    23641 tacgggagta ctgacaccaa catccggcac gatggaaatc gaaggaaaaa tctcagcttt
    23701 gctagaacta ggatcaggat tcaatcctga gtattctggc tatgaaaata tctatttaaa
    23761 tggaatggtt ctaggatttt caagagaaga agtcgatgaa atggtcgatg atatcattga
    23821 atttgctgac atcggagacc atatttatca acctgtaaaa acttattcaa gcgggatgtt
    23881 cgttcgtcta gcttttgctg tagcaatcaa tgtgaatccc gatattttga ttgtggatga
    23941 agcattggca gtaggcgatc ttgaatttca actaaaatgt atggaaaaat ttacagaaat
    24001 caagaactcg ggaaagacga ttttattcgt ttctcatgat atcagttcga ttcgtcgttt
    24061 ttgtgatcgt tcctattggt tgaaaaacgg agaagtcgtc gaatatggcg atacgatgga
    24121 agtaacgacg aattatgaaa actttttaaa gaaaaaatca gttaaaacag tggatcggaa
    24181 taaaaaccaa gtagaacggt tcgccgctcc agatatcgtc gacgtgacga aagcggaatt
    24241 gttggataaa gacaaaaatc cggtggatat gctggaacaa ggagaaaaac tatacgttaa
    24301 agtaacttat gaagtaaaag atgatacaat caaaaatccg gttttaggaa ttgcgctacg
    24361 aacagtcgac aatttttatg tatgcggact taatactcta ctagatggta tcaagattcc
    24421 ttggaaaaaa ggagagaata tcttttatct ggagtatgaa aagttaggtt tgttagctgg
    24481 tgaatattat tttgacgttg cggtctttga agaaaatgca acggttcctt tggtatataa
    24541 gacaaagtac atgaacttgt ttgtcagcgg ttcttatatc ggagaaggca tcgtggtctt
    24601 agaccataaa tgggaagaag ggactcatag caatgaaata tgattttgaa atggacctag
    24661 atgaacaaag cagtgtggga aaaattgccg cacagatcaa accaggaagt aaagttttag
    24721 agtttggtcc cggaaacggc cgattaacga aacatttaat cggagcaaaa caatgtgaag
    24781 tgagcattgt tgagttagat aaggaattgt tcgattttgt cagcgaattt gctcaagatg
    24841 gattttatgg tgatatcgaa agttttgagt gggcaaacta ttatgctgga cagacatttg
    24901 attacgtctt gtttgcggat gttttagaac atttggtaga tcctggaaaa acattgaaga
    24961 aagtcagaga atttttgaat gaagaaggag agatcctgat tacattccct aacttggcgc
    25021 ataattctgt catgatcgat ttgttcaata accaattgcc gtgggcttct tatggtctcc
    25081 tagatgaaac ccataattct ttttatactc atgatggctt ccaaaaagtt tttgaaaaag
    25141 cgggattatt cattaatatt gaagattatt tgtacttagc tgtaggtgat acagaattaa
    25201 aatcaactta tgaagaattg ccggaagctg tacgctatga tttcaaaatg cgaccatttg
    25261 gtgaagtcta ccaatacttt ttctcattga tgaaacatcc agtagcacaa agttccattg
    25321 cagagccaca aaattctaat tatgtaaaag tgttagaagt aacccagcaa acgaaacaag
    25381 atgaaacaat ccaacaaata ccattcaata atttcacagg ggaaaatgag acactaagtt
    25441 tccccgtatc agaaacaaca gaaagaatgg tgtttcgctt cgcgcaacaa cctagcttta
    25501 tcgaattcag cgcagaagct gccggagaaa aactaacatt tatcgattcg aatgctgtag
    25561 tcaaaacagt aaatgattgt tatttgtttg atgggaaaga attaccagag ttcgttctaa
    25621 cggatatttc tgggaaagaa gtgactatcc attgtcacta tcgctttatc ggggaattga
    25681 caccaacaat gaaagaattg ttggaaacga ttcgtcccat ggctgaagtc acaaagcagc
    25741 tttctgagaa aaatgacgaa ttagaaagag aaaatcatca tcttcttgag gaaaatacaa
    25801 gactagacca tacgttaaaa acaaccacaa atcgctattg cacattgttg gaaagtgatg
    25861 aatggacaat aaaacataga ctaggacgac gtaagaaaga aacttcgaaa aaaatccaag
    25921 aaaaagaact ttctatatgt attgacgaga aaatctggga tgcagaaaca aaaatattaa
    25981 aaatcatcgg atggggaatc gctaattcgg atcgccagcc cttgtcctat aagttatcag
    26041 ctgaccaatc gccatttttc gaagcaattc ctgtttcacg agaagaagtc aatcaagcag
    26101 aacagctcgc aaaaggaaca gaagcgggat ttgagttacg aatcctttgc gagcaagaac
    26161 gttcattctt agtggaagca gtagctcaaa atggccaatc atggatcatt gaaatgtaaa
    26221 taatgattaa cttataaaga taaggagtaa acgaatcgtg caaaaaaaag aaattgccgt
    26281 atttatcgat caaatcactc gtgaacgggc cactggcgat ttgcttattg tgggctgggc
    26341 aattgatgaa gtgaccaaag aaatccctac gataaaggta gaaaaagaaa atgtgattgc
    26401 tgaagcaaca catgtcgtaa gattggatat caatcattta tataatcttg atgttaagac
    26461 ccaaagcggt tttaaggtac gtttatcagg gaaaatgaga ggaaaagcca tcttagactt
    26521 ccaaacagcg agacatcaaa atggcatagc tgtgaaatta aacggtaaat acccttatga
    26581 tgacggcatt gaatcttcat gggaaagaaa aaaaagatta ctgaaaaaag ggataaatta
    26641 tgcaaggact catggcgtaa aaaaagcgat ccgtcgggtc aaattggaat tgaagccagg
    26701 atcgatcgac tatgcagagt ggatcagtcg tcatgagaaa ccagatttga aagagcaaag
    26761 gaaagaagca caaggatttg cgtaccgtcc attgatttcc atacttatgc ctgtctataa
    26821 cgttgaaatc aaatggctcg aaaaatgcat tgattcggta ctggatcaaa cgtatgatca
    26881 ttgggaacta tgtatcagtg atgatgcttc tactgatcca gctatccgaa agtgtctgga
    26941 atcctatcaa gcaaaagatg atagaatcaa agtcgttttc cgaaaagaaa atggacacat
    27001 cagtctggca actaattctg cattggaaat agcagaagga gaatttatag cactcttaga
    27061 taatgatgat gaattaccgc catttgcatt atatgaagtg gcaaaagtgc taaacgtaca
    27121 tccagaactg gatgtgatct acagtgacga agataaaatc gatgcagatg gcaatcgctt
    27181 tgatccgcat ttcaaagcag actggtcgcc tgatacattg atgggaaata attatatctc
    27241 tcacttaggc gtatatcgaa caagcattgt taaagaactt ggcggtttcc gtaaaggcta
    27301 tgaaggttct caagattatg atttggtcct tcgtgtgaca gaacaaatcc ctgcagatca
    27361 tatttaccac attgaccgag tcttgtatca ttggcggacg atcccaggat caactgcaag
    27421 taatggcgaa gccaaaagtt atatctatga ttccggagtg aaagcattga cagatgccct
    27481 gtctagaaga aacatcaaag gaagcgtacg tcctggcaga atttctggat tttatgagat
    27541 tgcttatgac gtcttgcaag aggatttggt cagtgtgatc attccaacga agaatggcta
    27601 tgaagatcta aaaacttgtg tggattcgat catcgaaaaa acgtcttatt caaattatga
    27661 aatcattatt gcggataacg gaagtacaga tccaaaaatg caagaattat ttgcagaata
    27721 caagcatcag ctgaaagacc gctttatcgt agaattgatt gacattccat tcaattattc
    27781 tcgaattaac aatttagcag cagaaaaagc aaacggcaaa tactttttat tcttgaataa
    27841 cgatacagaa gtgattgagc cagattggat gacggtgatg gtttcttatg cacagtttga
    27901 tcgaatcggc tgtgtaggag caaaactgtt ttatccagat gatacaacgc agcatgcagg
    27961 agtattatta ggaatcggtg gtgttgcagg gcatgcattg aataactatg atcgaacaca
    28021 ttgtggttat ttcggccgat tggtcattga cgtcaattac ttagcagtca ctgcagcttg
    28081 tatgatggtc aaggcagctg acttcaatgc tgttaacggg tttgatgaaa cattagaagt
    28141 agcattcaac gatgttgact tgtgcttgaa agtttatgaa ctgggtcgtt acaatgtcta
    28201 tgcacatcaa gcagaattgt accatttcga atctaaatca agaggttatg aagatactcc
    28261 agaaaaacaa agacgttttg ctggtgaaat caaaaaaatg caagataaat ggccagcata
    28321 tattgcgcat gatccatttt acaatgataa tttaacaaaa gaaggaatcg gcgacttttc
    28381 gttgagacca gattaaacta taataaaaag ctgttatgtt gtgattcgct cgcacataac
    28441 ggctttttat agttttttgt caaaaaaagg cagaaggtgc cgactcaaaa aaataagtcg
    28501 aggttgggac agaagtgttt aactccgaga aataagaaga aattcacgaa aattgctttt
    28561 caaatttttg tgaatttcgg cttatttaag aagaagttgc ttctgctccc accgtttatt
    28621 cgtttttaaa gaatgagaca aaagtgtttc ttacttttgt cccacgctct tattcatgct
    28681 cagagcgcca atagatacaa aatcatagcc aaagtttcac gaaccctagc tgtcaaagaa
    28741 tcgatatttt attttaatat aggctatttt aaaataaatg gtttaaggta ttcctctaca
    28801 aaagccactc tatcaattat catgggttta aaataagaag tgatggagat aaccagattg
    28861 ttcttagcgt caatataaag aacatttcca ctattaccaa ttgctgaata tatttcgttc
    28921 tcagaatcta atacccacca taaatagcca tatctcatat tttgtaagtc ttctaaagca
    28981 ctggttctag gtttgaacat ctcgtttatc cacatgggtg gtacgatttg ttttccttta
    29041 tacatccctt tatttaggca taatacacca atttttgcca gatcacttgc cgataaacac
    29101 aaaccatatc ctgccgtccc gatatttagt ggatcacaaa accagacatt ggttttagga
    29161 gacttatcca ttgtaaactg cttatgttct tcagctgttt cagcataata attgacatgg
    29221 tttggtatcc ctataggatc aaatagatac ttattggcaa aatcaacagt tgttagctta
    29281 cttgtctgat acaacaagcc agttaatatg tgtaaacaga cagtttgata gttgaattcg
    29341 ccggttatac cttttcttcc tcccaataaa tctagtgatg tttttgtcca atcttcactt
    29401 gaacagactt ttgtccatgg atcgccttta catttgtagg gtgctttcat tgttagcaag
    29461 tgcttgattg taatagcgta aatagttttc tccccgcgtt tcactttata ctctggaaaa
    29521 taatctaata ctttatcatc gatacttttg attaatcctt gctctaaagc aatgccaatc
    29581 agcaaagata caatactttt cgttgctgac atgatatgac aagtatcgtc ttttttataa
    29641 ccattccatt catctgtata aacttctacc ccatccttat atgcgacaat ttgacatata
    29701 tttggttgtc gaaaaccaat aaaatcatgc aactcttgtt tattcataag atattacctc
    29761 actttcttct ataagcataa tgtcattaaa aatcgatttc aattttttcg attcttcacg
    29821 taatacaggt attcttatgg actagacagc gctttgggaa gatggattct ctgaaaaata
    29881 taaaggttca ctttatgagt ggataaaaaa agcagcaaat acttcgactt ctttaattta
    29941 ccaacattag tgaaaatcga ttcatctgga gatttgtaat ttagagtcct tgtcttgatt
    30001 agaggtgtat aaagcttttt attagacatt tttaaattcc attacaattt gcttataaac
    30061 taggttttta aaggtgacta tggtaagata atagagatat tattttgtga ttaggagtgt
    30121 atatatgaat aaaaatggag aatggagtgc tgcacgacgg atattcatta tattaatgga
    30181 tgttattgta tacaatgcag caatatatag tagtttctta ctgaagtttc gtggagagat
    30241 cccattacga aatttagaaa ctttccaaca ctcagcaatt attatttcag tgatttttat
    30301 tgcgttgaac attttgttgg gtgcatatgt tttttataat cgaatgatca gtgacatcgt
    30361 gtttgtcaca gtcatcggtc aggtattgat gacactaggg atcatggtag tgacttttgc
    30421 gggccgctgg tttgcttttc cacgtcttgt tatcttactt tcatttgttc tcggtacgct
    30481 tttcttaagt atctatcgta ttctcgtata taaactttat ttacgcgtaa gtcgagataa
    30541 aaaggtcgtc attattgggt tagaaaagga tgtcgcacca gcaatccaaa attttggttc
    30601 aaagaaaaac aacaaacata aagtcgaagc agtcattctt gataactatt atgcaaacat
    30661 caaaaatatg attaaagaca tcgatattgt ctatcttgct tctcatatcg aagaaactga
    30721 aaaaatcaaa atctatcaat tagttactaa aaatgaaaaa aaattgtttt tgaatacaac
    30781 atttgaaaac ttgacattga tcaatccaaa tattatgaat ttcgaagatg aaagtattat
    30841 tgaagcatct ggatttagaa tccaacctga atatgaacta ttcaaacgtt tgtttgatat
    30901 catcgtttca cttgttttat tagttattgc ttcaccattt atgttattca cagcaatttt
    30961 agtcaaagtg acatcaccgg gaccaatcat ctataaacaa gtgcggatca caaaaaatca
    31021 aaaggaattt tcaatctata aattccgctc gatgaccgcc acagccgaag caaaatctgg
    31081 accagtttta gctaagagca atgatgcacg agtaacgcct gtaggtaaat ttattcgagc
    31141 tgtccgcttt gatgaattac cacaaatctt caatgtgctg aaaggcgata tgtcgatcgt
    31201 aggaccacgt cctgaacgtc ctttcttcgt cgatcagttc aatgcagaaa acccttatta
    31261 ctacttacgg cataatgttc gtgctggtat cactgggtat gcacaagtct atggaaaata
    31321 tgtctctgat tacaacagta aattacgttt tgatttactt tatatcaaaa aatattcatt
    31381 gatgcttgat ttaaagatct tgctgcaaac catcaagatc ctatttgata aaatgtcctc
    31441 tcaaggactt gaagaagacg aaaatgtgat ctcattggca gaaattgctt ttccgaatga
    31501 aaaaatcttt cgctagttgg gaggcgtaaa aatgaacaat ccgaaattca gcataatcgt
    31561 accagtatac aatgcagaag caactattgg tcgaacgatt gatattctaa aagaattgga
    31621 ttatgaagag tacgaagtcg ttttagtaaa tgatggatca acagatcaaa cacaggaaat
    31681 cattcaagaa ctgattgaaa atgatgaacg ttttgaattg attactacga ccaatcaagg
    31741 gcccggatta gcaagaaacg aaggaataag acagtcaaaa ggagaatatc tcttattctt
    31801 cgatgcagat gacacgccag taaaaacgat cttgtcagat tatgatcatt tgctagaaaa
    31861 gagtccaaaa gcggatcttg ttgttagttc gtttgttttt cgtacaatgg acgagggaag
    31921 aatcgtttcc gaaaaagaaa acttagttac agaatgtcac tatctaactc acgaagagtt
    31981 tataaaagac atgtatcagt taatgaatga acagttgatg tatgttgtat ggaacaaatg
    32041 ctatcgtagc gatattctga aaaataacca aattctattt aaaacttata atagttgtga
    32101 ggatcgaata tttaacttac attattatga atactgtcat caagtgatca tgaacccaaa
    32161 agtagaatat atttatgaat ttgaaggtgg gaaggggatc actaatcaat accgacctaa
    32221 caagttcgaa acatttaaag aattctattc attagcaaat actgtaacag acgatattaa
    32281 taaagacggt atggcggcgc ttcttttaaa agggacaact tcagttattt tttctattta
    32341 tagtacctct gcaagaactt caaaagagaa gaaagacgaa gcaaagcaga tattgagtga
    32401 tccagtgatc cgagaagcca agcaaattgc taagacggat tcttcagcaa aaaaaataac
    32461 aaagttgctt tacaatatgc cagctccact atttttatct gctgtaaaag ttggaagctt
    32521 cgttgaagtg aaaatgccag ggttaatggc tgctttgaag cgagtatatt agttaatgga
    32581 ggaaaatata atgaaaagaa ttttgcattt tcagggacga atgggtttag gtggagcaga
    32641 gtctttcatg atgaatttat atcgtaaaat tgatcgtaca aactatcaat ttgatttttt
    32701 gatttatgaa gattatgcag atgttcaaga ctatcattca gagattgaaa gattaggagg
    32761 ccgtattttt gttgtaccta atcctaagaa aaatattttt aaatatttaa tagaagtgaa
    32821 taagttacta aaaaaagaat ctttttctat agttcacaat caggtttatt ttggcggggg
    32881 aattaattta tggttagcca aaaagaatgg aatcagacag agaattgctc atagccatgc
    32941 aactgaagat ggaaaatctc aaaatattgt aatgaatgta ttgcgtaaat ttttaaccaa
    33001 attgttgtta caaaatgcaa cagactacct tgccgttagt caagaagctg gtgaaagtct
    33061 gtttcaaaac cacccctttg agatagttca taatggtatt gatttagagc tttatagtaa
    33121 aaattcagaa gctaaggtta ataagagaaa agaattggat atctcaatga gtacttttgt
    33181 tgtgggaaac attggacgat tagagaaaca aaaaaatcaa tcttatttgt tagagatttt
    33241 tttagaaata ctaaaaatga attctgattc ttacttgatt ttagtaggtg aagggtcact
    33301 tagaaataaa ctgaaagcca aagcagtaga attggatata gagaaaagag taaaattttt
    33361 aggagaaaga aacgatattc ccgagttatt atctgtgatg gatgtttttg taatgccttc
    33421 tctttatgaa ggtctgccaa tggttggatt agaagcacaa gcagcaaaat taaaattagt
    33481 cttagcagat actatttcca aagatacaaa gttaacaaat aatgtggatt ttgtatcatt
    33541 agatgaaaca ccacaagaat gggcaaaaaa agtaataaaa gagccgtatg ctaataaaat
    33601 aacacaagaa ctaaagagtt atgatgtttc gtacactact gaacaaatgg agagtatata
    33661 tagtagagat cattaaaaat gttcaagata ttttaggagt gattattttt gaaaatatgt
    33721 tatttgatat tggcatacaa tgatattggc aacttaaaga gattggtcaa tcgattgaac
    33781 gaaaatgcag tttttattat tcatatagat aaaaaaactg atatagaacc atttattgaa
    33841 gcatttaaat catatgataa tgttgaattt ttatgtaata aaaaccgtgt taaaatttat
    33901 tggggtggtt tttccattgt acaagcagaa atcaatttag taaagagagc attacaaaat
    33961 gagaaatatt taaaatatgt attattatct ggtgctgatt atccaatcaa agataatgag
    34021 tatatttata attattttaa aaagaatagt tcagtggagt ttattcgtgg aatagatcta
    34081 gatcaaatta aacataa
//
LOCUS       DAFLVO010000026        33264 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.026, whole genome shotgun sequence.
ACCESSION   DAFLVO010000026 DAFLVO010000000
VERSION     DAFLVO010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33264
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.026"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(42..230)
                     /locus_tag="L1U99_001279"
     CDS             complement(42..230)
                     /locus_tag="L1U99_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBN1211830.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            500..862
                     /locus_tag="L1U99_001280"
     CDS             500..862
                     /locus_tag="L1U99_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBN1211831.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            914..2596
                     /locus_tag="L1U99_001281"
     CDS             914..2596
                     /locus_tag="L1U99_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBN1211832.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2713..4749
                     /gene="recG"
                     /locus_tag="L1U99_001282"
     CDS             2713..4749
                     /gene="recG"
                     /locus_tag="L1U99_001282"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBN1211833.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4798..5799
                     /gene="plsX"
                     /locus_tag="L1U99_001283"
     CDS             4798..5799
                     /gene="plsX"
                     /locus_tag="L1U99_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBN1211834.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            5921..6163
                     /gene="acpP"
                     /locus_tag="L1U99_001284"
     CDS             5921..6163
                     /gene="acpP"
                     /locus_tag="L1U99_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBN1211835.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            6431..7435
                     /locus_tag="L1U99_001285"
     CDS             6431..7435
                     /locus_tag="L1U99_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1211836.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            7436..8380
                     /locus_tag="L1U99_001286"
     CDS             7436..8380
                     /locus_tag="L1U99_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1211837.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            8380..9342
                     /locus_tag="L1U99_001287"
     CDS             8380..9342
                     /locus_tag="L1U99_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1211838.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            9369..10283
                     /locus_tag="L1U99_001288"
     CDS             9369..10283
                     /locus_tag="L1U99_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1211839.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            10309..12090
                     /locus_tag="L1U99_001289"
     CDS             10309..12090
                     /locus_tag="L1U99_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1211840.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            12438..13124
                     /locus_tag="L1U99_001290"
     CDS             12438..13124
                     /locus_tag="L1U99_001290"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBN1211841.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            13144..16725
                     /gene="smc"
                     /locus_tag="L1U99_001291"
     CDS             13144..16725
                     /gene="smc"
                     /locus_tag="L1U99_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBN1211842.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            16734..17543
                     /locus_tag="L1U99_001292"
     CDS             16734..17543
                     /locus_tag="L1U99_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1211843.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            17554..18552
                     /gene="ftsY"
                     /locus_tag="L1U99_001293"
     CDS             17554..18552
                     /gene="ftsY"
                     /locus_tag="L1U99_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBN1211844.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            18739..21006
                     /gene="gshAB"
                     /locus_tag="L1U99_001294"
     CDS             18739..21006
                     /gene="gshAB"
                     /locus_tag="L1U99_001294"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HBN1211845.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(21095..21547)
                     /locus_tag="L1U99_001295"
     CDS             complement(21095..21547)
                     /locus_tag="L1U99_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HBN1211846.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            21697..22647
                     /locus_tag="L1U99_001296"
     CDS             21697..22647
                     /locus_tag="L1U99_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBN1211847.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            22640..23599
                     /locus_tag="L1U99_001297"
     CDS             22640..23599
                     /locus_tag="L1U99_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBN1211848.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            23596..24351
                     /locus_tag="L1U99_001298"
     CDS             23596..24351
                     /locus_tag="L1U99_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1211849.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            24374..25327
                     /locus_tag="L1U99_001299"
     CDS             24374..25327
                     /locus_tag="L1U99_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1211850.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(25971..26267)
                     /locus_tag="L1U99_001300"
     CDS             complement(25971..26267)
                     /locus_tag="L1U99_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HBN1211851.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            26622..26978
                     /locus_tag="L1U99_001301"
     CDS             26622..26978
                     /locus_tag="L1U99_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBN1211852.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            26988..27887
                     /locus_tag="L1U99_001302"
     CDS             26988..27887
                     /locus_tag="L1U99_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HBN1211853.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            28404..29135
                     /locus_tag="L1U99_001303"
     CDS             28404..29135
                     /locus_tag="L1U99_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBN1211854.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            29280..31307
                     /locus_tag="L1U99_001304"
     CDS             29280..31307
                     /locus_tag="L1U99_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBN1211855.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            31415..32512
                     /locus_tag="L1U99_001305"
     CDS             31415..32512
                     /locus_tag="L1U99_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBN1211856.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            32819..>33264
                     /locus_tag="L1U99_001306"
     CDS             32819..>33264
                     /locus_tag="L1U99_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1211857.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT        11139 a         5762 c         7123 g         9240 t
ORIGIN      
        1 aaaaaaccgt tcactatctg aacggtccaa gtatcattca attaaacgcg ttcaactttt
       61 cctgatttca aagcacgagt tgacacccaa acttttttag gttttccgtc gaccataacg
      121 cgaacttttt gtaagttagg tttaacagta cgttttgttg agttcatagc gtgtgaacgg
      181 ttgtttccac tttttgtctt gcgacctgta aagtaacaaa cttttgccat ggtaatttcc
      241 tcctttgcct tgatttggag caatagaata attcagctca taccagacta acatatcata
      301 tagaatggaa atttgcaagt acattttcat agatacaatt gacaattgag aagaataatt
      361 gtaaattaaa caaggttata cctgaaattt tgcaaggttt ttgagtactt tgggtaactg
      421 ccttttattt caagttgcgc tatgataaaa tatgatagaa gaaaaatggg agttttttac
      481 ccgttaagga ggctcattca tggctgtaaa aattcaaacg tcagctggaa ccattgaaat
      541 taccaatgat gtaattgcaa cagttgttgg tggcgccgcg acagatgtgt tcggtgttgt
      601 aggaatggcc agcaaaaatc aaattaaaga taatattact gagattttgc gtaaagaaaa
      661 ttactcaaga ggagtagttg tccgccaaga agataatggt attgctgtag atgtttatac
      721 gattatcagc tatggtacga aaatctctga agtttcccgc aacgtccaag aaaaagtgaa
      781 atacaatcta gaggcattat taggcgtaac tgccaattca gttaatgtct ttgtacaagg
      841 tgttcgtgta ctgccagact aggcaggaga ctggctggta actcagcagt cgatctgaag
      901 gaggattatc taggtgagtg taacagaaat aagtgcaagc cagttccagg aaatggtcca
      961 ggcaggtgcg aatcgtctgc aagtaaatgc agaatacgtc aattcattaa atgtattccc
     1021 tgtgccagat ggcgatacgg gaacaaatat gaatctatct atgactagtg gagctaaggc
     1081 agtagtagat tcaacctcag aaaaagtagg agaattagca gcaatgcttt caaaaggatt
     1141 gctgatgggt gcgcgcggaa attccggcgt tattttgtct caattgtttc gtggattttc
     1201 taagcaaatt ccagatgttg tctcattaaa tgcttccgat cttgctgcag ccttcactca
     1261 tggagttgaa actgcgtata aagcagtaat gaaaccagta gaaggaacga ttttgacagt
     1321 agctagagaa gcagcgaaag ctggagaaaa gaaagcaaaa agtactgatg atgtcgttga
     1381 agtaatgaca gctgttgtaa aaggggcaaa gcgtgcttta gctaaaactc cagacttgct
     1441 tccagtccta aaagaagtcg gtgtcgtaga cagtggaggg caaggactgc tgtttgttta
     1501 tgagggcttt ttaagtgcat tgaatggaga attccaagcg gatgaaacat atgaaccttc
     1561 tccagcagaa atggatgata tggtcaatgc agaacatcat cgcagtgtcc aaggtcaaat
     1621 ggcgacagaa gatatccatt ttggttactg tacagaaatc atggtaaaaa tcggagaagg
     1681 acctacagtc gatagtacat tcgattacga agaattccgt aactatttag atggtatagg
     1741 agattcttta cttgtggtca atgatgacga gatcatcaaa gtccacgtgc atacagaaaa
     1801 cccaggagaa gtcttgaatt atggacaaaa attcggttca ttagtcaaaa tcaaagtcga
     1861 caacatgcgc ttgcagcatg agacgatttt ggaacacgat gaagaagtga acgagtttgc
     1921 gaaaaaagaa acaccacgta tcccgtatgg tatcgtagcg atcgctgctg gtaaaggcgt
     1981 ccaagagctg tttgaaagtt taggcgctaa ttatgttatc agtggtgggc aaacaatgaa
     2041 tccaagtacg gaagacattg ttaaagcgat tcaagaagta aacgcagata aagtgattgt
     2101 cttgccaaac aataagaaca tcttcatggc agctgatcaa gcagcagaag tagcagatat
     2161 cccagtagca gttgttcctt caagaacgat ttcccaagga ttgacagcta tgctttcatt
     2221 caatgatcaa gcttctttag aagaaaacaa agaaacgatg acagaaatgt tgtctagcgt
     2281 tgtgagcggt caagtcactc acgcgatcag agatacctca attgacggtg tagagatcaa
     2341 agaaggagac tttttgggca tgatcgatgg aaaaatcctg atctctaacc cagatatcac
     2401 agcaacagcg ttaagtacac tagaacaaat gatcaatgag gacacagaga tcgtaacgat
     2461 cttggcaggt gatgaaggaa cagttgaaca agcaaatgaa tttgctgaga aactaacaga
     2521 aaaacatcct gatttggaaa tcgagatcca ccaaggagat cagcctgtct atccttatct
     2581 attttctgct gaataatttc tgtgtcagaa tatctttcta acacagtatt cattcataaa
     2641 aggccttcgg ttagtgatca ggtatgatcg ctgaccaagt cctttttttg ttaagggagg
     2701 gaggaaaaat ttatgcgttc tttagatgat ccaatcacta tgctggcagg agtcggagaa
     2761 aaaagagcag ctagtcttgc cagcttgggc atccaaacga ttgaagactt actgacttat
     2821 tatcctttcc gctacgaaga tattcaggaa agaaatctaa acgagatcca agatcaagaa
     2881 aaggttactt tgaaaggaat cgtagtctcg cctcctgtga tgaatcgatt tggttataaa
     2941 aaaagccgat tgcaatttcg tatgatgcaa gaacatgatg tgttcaacgt ttcttttttt
     3001 aatcaacctt atctaaaaga aaaagtcatt ttatcggagg aaatcgccgt atacggtaaa
     3061 tgggatgcaa agcgtaaagc attgaacggg atgaagattt taggttctca aacaatggat
     3121 gacttttcgc cgatatatca cgtcaacaaa tcaattcgtc aaacgacatt agttgatcta
     3181 atcaaaaaag ggtttcaaga atacggcaca ttgattgaag aaaatctgcc aaacaacctt
     3241 gtggagaaat atcgactgct tgaccgagct tctgctgtaa gaagtatgca ttttccaaaa
     3301 gaccacgaag aaaaccatca agccaaacga cgtgtcgttt ttgaagagtt ctttttattt
     3361 caaatgcgtc ttcaaggatt gaaaaaagca gaaaaagcag aaacgaatgg tttggagatc
     3421 ctttatgatg tccaaaaatt gaaagaattt actcaaaagc taccttttga actgacaaat
     3481 gcacaaaaac gtgtaacgaa tgaaatctgt cgggatcttc gcagtccgca gcatatgcag
     3541 cgacttttgc agggagatgt aggtagcgga aaaacagtgg ttgccgcgat tgcgttatac
     3601 gctaccgtta cagcaggttt ccaaggtgcg ttgatggtgc ctacagaaat cttggcacaa
     3661 caacatatgg aaagcttgca acagctgttt gatcccaatg aagtaaccat cgcattgctt
     3721 acggggtcaa cgaaagcaaa agaacgtcgt gagctccttg aaaaactaga gcaaggggaa
     3781 attaacatcg tgatcggcac acatgcattg atccaagatg gagtcgaatt tcagaattta
     3841 ggtctagtta ttacggatga gcagcaccgt tttggcgtga accagcggaa agtacttcgt
     3901 gaaaaaggct ggcgaccaga tgtcttattt atgacagcga ctccgattcc tagaacatta
     3961 gctattacag catatggtga gatggatgta tctatcattg atgaacttcc agctggacgt
     4021 atcccgatcg aaacacgctg ggtaagaaca cctcaattgg acagtgtact ggattggacg
     4081 aaaaaagaac tggcaagagg acatcaaatg tatgtcatct gtccgctgat tgaagaatca
     4141 gaagcattag atgtaaaaaa tgcagtggaa atctatgaaa aacttcgtga actatttgca
     4201 ccaaaatatg aagttggctt gttacatggt aaaatgaaga atcaggaaaa agaagtaatc
     4261 atggaagcct tcaaagacaa ccagatgcag atattagttt cgactactgt aattgaagta
     4321 ggggtaaacg tgccgaacgc gaccgtcatg ctgatcatgg atgcggatcg atttggattg
     4381 gcacagctgc atcaacttcg tggacgtgtt ggacgcggaa gtgatgcttc ctactgtatc
     4441 ttagttgcta atcctaaaaa tgaactaggt gtggaacgga tgaaaatcat gacagagacc
     4501 accaatggtt ttgtactaag cgaaaaagat ctggaattac gtggtcctgg tgaagtattt
     4561 ggcttccgtc aatctggtct gcctcaattt gcgattgctg acttggtgac ggatggaaat
     4621 gttttggagg tagccagaga agaggctgca gccctttggc agataaagga ttggcagatg
     4681 cttcctgagt atcagccttt agcgcaaagc ctccaaatag aaaatcagga taatcgttat
     4741 ttcgattagc agactgtgct atactttata ctgatgacgg aaaaaggagt ggaaacaatg
     4801 aaaattgccg tagatgcaat gggcggagat cacgcacctc aagcaattgt agaaggcgtg
     4861 gctttagcgc agcaagattt tccagaagta gaattcttac tttacggaaa agaagcagaa
     4921 atcaagaaat acttaacaaa tgaaaaaaac atcacgatta tccatacaga cgaaaaaatc
     4981 aatagtgatg atgagccagt aaaagcaatt cgacgaaaaa agactgcatc aatggtcctt
     5041 gctgcacaag cagtgaaaaa cggtgaagca gatgctgtat tttcagcagg gaatacaggc
     5101 gcgctactag cagcagggtt gttcatcgta ggacgtatca aaaatatcga acgccctggc
     5161 ttgatgtcta ccttgccagt agtagggaaa gaaggtgccg gtttcgatat gctggatctt
     5221 ggcgctaacg cagaaaacaa accagaacat ttgttgcaat acggtatttt aggttctttt
     5281 tatgcacgta aagtccgagg tatcggacgt cctcgtgtcg cactcttaaa caacggaaca
     5341 gaagcaacaa aaggtagtga agtgacgaaa aaagcctatg aactccttca gaatgaaaca
     5401 agcttgaatt ttattggaaa cgtagaagct cgtgagctac tcaatggtgt ggctgatgta
     5461 gtggtcacag atggatttac aggcaacgct gttttgaaat ctattgaagg aacagcaatg
     5521 aatatgatga atctattaaa atctgctatt ctaaatgaag ggatcaaagg aaaaatgggc
     5581 gctatgcttt taaaagacgg cttacgttct ttgaaagcag aaatggatta ttccaaacat
     5641 ggcggtgccg ttttgtttgg cttgaaagca ccagtcatta aaactcatgg agcaacaggc
     5701 cccgatgctg ttcgctatac gatccgccaa atccacacaa tgcttgagac agatgtagtt
     5761 ggacaattag tcgaacaatt tgaaaaaagc gaagaatagt atttggatat ctgaagcaat
     5821 ccgttccatt gaaaaaaagg tggacattcc tgaaaaatgc cagtaaaatt agccatggtg
     5881 taggtaattg acaagtgtat gattcttgga ggtgaaaaag ttgactcgcg aagaagtatt
     5941 taacaaagta gcgaaaatta tttcaaatca ttttgagata gataccgata aagtgacgga
     6001 tgaattgaac atcaaagatg atttaaaagc tgattcaatt agtattatgg aattcgtttt
     6061 agagcttgaa gatgaattcg gtacggaaat ttcagatgaa gacgctgaac aaattgaaac
     6121 agtcggtggc gcagtagatt atatcagcag ccatcttaaa taatttcaaa taaaagcaaa
     6181 gaaggataaa aagctgcata cagcttttta tccttctttt tttaatcttt ttgacacgta
     6241 aaagtcattt ttctgataat tctggcgata aacagaaatt atgttgcaaa gtaaagcgat
     6301 tttctatata attattaata attcattaca caaagataag aataaccttt gttataaaac
     6361 gctttattct gtgtaatgtc cttttttatt aagaaaaact tccatttagg aagcagagag
     6421 gggtattcga ttgtccgata accaattatt agaagttcag aacctacata caggattccg
     6481 actcaaagat gactattacg atgcagtaga tgacgtttca tttactttag acaaaaacga
     6541 gattttagca atcgttgggg aatctgggtg cgggaaaagt accttggcta ctacgattat
     6601 gggattactt gatcctaata acacaaaaat tacaggtgag attttatata acgatctgaa
     6661 tttaatcgac ctgaacgaaa cgctctataa taaaatccgc ggaaatgata tcggaatgat
     6721 tttccaagat ccgttgtctg cattaaatcc tctcatgaga atcgaagacc agatcaaaga
     6781 aggactttcc tatcacacaa agatgaatgc agaacagcgt caagctcgtg cactagaatt
     6841 gctagaacaa gtagggattc ctaatcctgc gagagttgga cgccaatatc cccatgaact
     6901 atcaggcggt atgagacaac gtgtcatcat cgcaatcgca atcgcctgca aacctccaat
     6961 cgtcattgca gatgaaccga cgacagccct agatgtaacc atccaagcac agattcttga
     7021 tttactgaaa gaccttcagg aagaaacaaa aacagggatc atcttgatca ctcatgactt
     7081 aggagtcgta gcagaaatgg ctgatcgagt ggcagtgatg tatggcggac agttcgttga
     7141 agtagcaggt gtaaaagaac tgtttgatca tcctaagcat ccttatacac gctctttact
     7201 gaactctata ccacaagaag gaaatcatga tgcagaactc catgtgatcg aaggtgtcgt
     7261 tccttctctg aaaaacatgc ctcgtaaagg ttgtcggttt gcaccacgta ttccatggat
     7321 accagcaagc gatcatgaag aagagcctat ccttcatgaa gtcgcaccga accacttggt
     7381 acgttgctcc tgctataagc atttccactt tagagacgaa aaaggagagg tgtagatgac
     7441 agaattaatc acaatcaaag acctgaaagt tcattaccct attcgcagtg gattcttcaa
     7501 tcgagtaacg gatcatgtat atgctgtaga tggtgtggat tttattatcg aaaaaggaaa
     7561 gacatatggt ttagtgggag agtctggctc tggaaaatct actacgggaa aagccgttgt
     7621 gggattagaa aaggtaacag ccggacaaat catgtatgaa ggaaaagatg taacgaagcg
     7681 aagcaaccgc aaaaaaatgg gttataacaa ggatgtgcag atgatcttcc aagattcaat
     7741 gtccagtttg aatcctaaaa agcgagtgtt ggatatcatt gctgaaccca tccgaaattt
     7801 tgaacggtta agcgatcaag aagaaaagaa aaaggtaaaa ggactgctag atatcgttgg
     7861 gatgccggaa gatgcgctat ataaatatcc tcatgaattt tcaggcggac aacgtcaacg
     7921 tctaggagta gcccgtgctg ttgctaccaa tccaaaactg atcgtagccg atgaacctgt
     7981 atctgctctg gatctatctg ttcaagcgca agtattgaat ttcatgaaac gaatccagca
     8041 agaatacggc ctcagctatt tattcatttc acatgattta ggtgtagtaa aacacatgtg
     8101 cgacaatatc gcaattatgt acaaaggtcg atttgtagaa atcggtacaa gagaagacat
     8161 ttataatgac ccgcgacata tctatacgaa acgtctgctt tcagctattc cgcaaatcga
     8221 tgtagaaaat agggaaagcc acaaagaaaa tcgacgaaga gtagaacaag agtatatcca
     8281 aaaccaaaaa gaatactatg atgcgactgg tcgagtctac gatttgcgta cgatcacaac
     8341 tacacacaaa gtggcgttga aagatggagg tgcaagctaa tgtggaaaac gattctgcga
     8401 cgtgttttat tgatgatccc gcaagttatt attttaagtg ttctgatctt cttattagcc
     8461 caagcgatgc cgggggatcc atttaccggt ttgatcaatc caaatcagga tccggcagtg
     8521 atcgaacaga tgcgacaagc agctggcttg aatgacccat ggtatgtcca gtacttccgt
     8581 tggatcggaa atgctttgca aggcgatttt ggtcaaagtt tcttatacaa acgctctgtt
     8641 gctgacttga tcggcgaacg gatcatcaac actttatatc tatcgatctt gacagttgtc
     8701 cttacttatt tgattgctgt gcctctgggg atgcttgctg gccggtatca aaattcaatc
     8761 ttggataaga ttgtcgtaat ctacaacttc tttagttttg ctgttccttt atttatcttc
     8821 ggcttgatca tgctatttgt ttttggttat cgtttaggct ggttcccaac aagtggatca
     8881 caaacactag gtttgcaagg tggatttatc actcaatgga tagaccgttt gaaatatatt
     8941 ctgttaccat caattaccca agcatttttg gcgactgccg tcacaatcca atatctgcga
     9001 agtgaagtaa tcgattcgaa atcgctcgat tttgtcagaa cagcccgttc caaaggggta
     9061 ccgacgaata aagtattcag tcgacatatt ttccgaaatg cagcgttgcc gatggcttct
     9121 caaatggggt atgaaatcac ttcgttgatt gctggttctg tagttatcga aaagattttt
     9181 ggttatccgg gagtcggaaa actatttatt gattccatcg gccaacggga ctataccgtg
     9241 atcacatcct tagtattgat tttaggaatc gcgacgctag tggggacatt actttcagat
     9301 atcatcatga gtatcgttga cccgcgtatt cggattcaat aaaaccaatc agaaaggaga
     9361 atggatcgat gagtgaaaaa aacaatacag cagttcaaga aagtattcct cctatgggga
     9421 tacgaatgat tgctcgagaa tttaaaaaag ataaaattgc tattttttca ttaggtttgc
     9481 tagtggtttt attattagtg atctttatcg gtgcgatgct gaccgatcaa gacaaagtga
     9541 tgtatgttag tatcttcgac aaatacgctg caccaggaac agtttcgaca caaggacaaa
     9601 agttcattct gggagcagat gaaggcggac gtgatgtatt aggacaattg atcataggtg
     9661 ctagaaactc tgttacgatc ggatttgcga tcacgatcct tacttcgatc atcggggttg
     9721 gattagggat catctctggc tactacggag ggatcattga caacatcttg atgcggatcg
     9781 ttgattttat catgattcta ccgatcatgc tgatcattat cgtcttcgta tcgattattt
     9841 ccagatacaa tgtctggtcc tttatattca tcatgagtgc attttattgg gtagctaaag
     9901 cccgattatt ccgaagcaag acattatctg aagcaagaag agattatgtc agtgcctcaa
     9961 aaacaatggg aaccaatgat tttaaaatca tgttccgcga aatcatgccg aatctaagtt
    10021 cattaatcat tactaatttg acgatgaact ttgcggcaaa catcggtatc gagacaactt
    10081 tgactttctt aggtttcggc ttgccggcaa atgtacctag tttaggtaca ttgatcggtt
    10141 atgcaagtaa cggagaagtc ttagtgaatc ggcaatggat ctggttaccc gcatcaatcc
    10201 ttattttagt tttgatgttg agtatcaatt atgttggaca agcattcaag cgttctgcag
    10261 atgcgcgcca acggttaggc tagtatagaa gcgaaggggg aaataggaat gaagaaaacg
    10321 atttttggat ttgcagcgct gatgtctgct gtcgttcttg cagcatgcgg gggcggaggt
    10381 acagatacct ctggaaacaa ctctggaggc aacggcaata acaaagagga attaactttt
    10441 ccaattgcaa caaaaaataa tgatgatgca atcgaagacg gcgaattaga agctgcggtc
    10501 gcaacggaca gtcagtttaa aggattgttc cagtgggagt tttaccaaga ttcatatgat
    10561 gcagctttta tggctccttc tcatgaaccg ctatttgcaa acgatgacga tttcagaatc
    10621 acagacgacg gagctgcaac gcttgatcta gatgaagata cgaaaaaagc gacaatcaaa
    10681 gtaaaagaca acgtcaaatg gtcagatggt gaagatgtaa cggcggacga tgtgattttc
    10741 ccttacgaaa tcattgggaa taaagattac actggtatcc gttatgacga cactttccgt
    10801 aacatcgtag gtatggaaga atatcatgat ggaagtgccg acacaatctc cggaatcaaa
    10861 aaaatagacg acaaaacagt tgaaatcgaa tataaagaag taaacccaag catgcttcaa
    10921 tcgggtggtg gtatctggtc atatgcagca ccaaaacata cgttagaagg tgtagcaatc
    10981 aaagatatgg aatcaagcga tcaagtacgt aaaaatccag tgacttttgg cccttattac
    11041 atgagtaata tcgttgcagg agaatcagta gaatacttgc caaacgagca ctactggaat
    11101 ggtacgccta aattgaaaaa gatcacgatg aaatctgtac cgatggcaag tgcaactgaa
    11161 gcattgaact ctaaattata tgatatgatt ttccaaatgc caacagatac ttacgatacc
    11221 tataaagaaa ttgctggcta tacaaactta ggccgtgaac aaacttctta tacttatcta
    11281 ggattcaagt taggtaaatg gaatgcagat acaaagagtg tggaatacaa tccagattca
    11341 aaaatggctg ataaatcatt acgtcaagca atgggctatg cattagataa taatgcagta
    11401 ggtgaacgtt tctatgcagg tttgagaagc aatgcgactt cattgattcc tccagtattc
    11461 cagtcatacc atgatgatga gatgaaagga ttcacacaag atctagacaa agcgaaaaaa
    11521 ctattagatg atgctggcta caaagatgtg gatgacgatg gtttaagaga agacaaagat
    11581 ggaaataaac taacaatcaa ctttgcttcg atgtccggtg gggaaacagc gcaaccattg
    11641 gcagattact atatccaaca atggaaagaa attggtttgg atgtccaata cacaacaggt
    11701 cgtctgatcg aattcaattc tttctatgat aaattagaaa acgatgatcc tgaaattgat
    11761 gtttaccaag ctgcttggaa tacaggaact gatccaaatc caagtggact atggggacca
    11821 aatgctgcgt tcaactacac tcgttatgaa tcagaagaaa atacaaaatt gatcaacgat
    11881 atcagttcaa gcaaagcatt tgatgaagag taccaaaaag aagcatatca aaaatggcaa
    11941 caatatgcat ttgaagaagc atttgcgatt ccaacgttgt tccgtaatga agtattgcca
    12001 gtcaacgacc gtgtcaaaga ctgggattgg tcttatgatg taccaaaccc atgggcaaat
    12061 gtttctgtta cagcagattc acgttcataa tcactaaaaa tgaccgaaaa agggcgatgt
    12121 cctttttcgg ttttttgata tttttctgtt tatttctcta atattcaggt caaggcgctg
    12181 atttcatgac ttctccaata aacggtgttc aaagtccagt ttctcggtat taagtcaaat
    12241 ttatgcaaaa atatggaaag ccattttcac aaaatttttt cttcatactc gaaactaaac
    12301 gaatttttca caacttctcg tcaatcacta ggattattaa agctttactt accttttgac
    12361 cgaaccattt caaatttgac aaaaaaccag tataataagg aagtatcgaa aaaatatcca
    12421 taaaaggaat gtggaaaatg gacaaccagc tgacaaaaga actaaaagaa aactataaca
    12481 tcgtttttca cgatctaaat ttgcttgaac aagcttttac ccattcatcc tatgtgaatg
    12541 agcatcgcaa tctgcaatta tcggataatg agcgacttga atttttagga gatgccgttt
    12601 tagaactgat ggtttctcag tatttattcc gtttatatcc tcatttgcca gaaggaaaat
    12661 tgacaaaaac acgagctgcg atcgttcgcg aagacagctt gtcgaaattt gccaaagaat
    12721 gtcactttga tcaatatgtt ttgttgggca agggagaaga gaattcagga ggacgtacgc
    12781 gaccagcatt gctttgcgac ctattcgaag cttttttagg cgcgttatat cttgaccagg
    12841 gattcgacac gacccatgca ttcatcgaaa aagtgatttt tcctaaagtc aaagcaggtg
    12901 ctttttcaca tgagatggat cataaaacaa aactacaaga agtcttgcaa aaatcaggtg
    12961 atgtatcaat cgaataccga ttgatcaatg aagaaggtcc agctcatgaa cgagtatttt
    13021 ggatcgaagt ttatgtagat gatcaattga ttggcactgg acaagggaaa tcgaaaaaat
    13081 tagcagaaca agctgcggcg gaaaatgcat tggcagcact gtaaaagtaa gtgagggaaa
    13141 gctttgtatt tgaaacgaat tgaaatagcc ggttttaaat catttgcaga caagacagtc
    13201 attgattttg aaaatagcgt cacagcagtg gttggaccaa atggcagcgg aaaaagcaat
    13261 attacagagg ctatccgctg ggtattagga gaacaatctg ctaaaagtct gcgaggcgga
    13321 aaaatgccgg atatcatctt tgccggttcc gatacccgta agcagctgaa tattgcagaa
    13381 gtcacagtga ttttagacaa tagtgatcat tatctgccat tggagtacaa tgagatcagt
    13441 gtaacccgcc gttatcgacg gactggggaa agcgagtttt tcatcaataa acaaagctgc
    13501 agattaaaag atatccaaga attgttctta gattctggat taggaaaaga atcgttctca
    13561 atcatttctc aaggaaaagt agaagcgatt ttcagtagta aaccggaaga ccgtcgtggg
    13621 atctttgaag aagcagctgg tgtcttgaaa tacaagcagc ggaaaaagaa agcagaacag
    13681 aagctttttg aaacagaaga caacctcagc cgcgtccaag acatcatcca cgaattggaa
    13741 gaacagttaa ctcctttggc cgcccagagt gaggcagcaa aggagttttt acggctaaaa
    13801 gaaacactga ctcaaaccga tgtctctttg atggttgctg aaatcaagac agcaaaaaaa
    13861 gattgggaca acaaacaagc acagcttgcg aaattcaatc tagaattagg caaactatct
    13921 gagtcgatcc aagaacaaga atccattttg gcgaagcagc gtaaagaaaa tgcgcaagcc
    13981 gatcgtctga tcgaaaaaaa tcagcaagta ttattagatc tttcggaaaa actgaagcag
    14041 acagaaggac aaaaagatgt tttgcaggag cggacaaagc atacacaaaa aagctcgcaa
    14101 gaatatcaaa cttcattagc agaagcacaa aaaaaggtta aacattttga aaagcttcaa
    14161 gaaagcttga tgaaagcagc agcagaaaaa gaaacagaga tccaaaaagc tgaagcaaat
    14221 ctcataaaaa cacagcaaga attagaaaaa taccaaaaat caacgaaaga attattggca
    14281 gaattaagag atcaatatgt tgatttgatg caagaacaag cagctgtagg aaacgaactg
    14341 aagtatctag aacgtcaata tatacaagaa acagcaaaaa gcaagcagac gttagccaag
    14401 caatcggaag tagaagcatc agtagaccga ttgatcttac aaaaagaaga attgacacaa
    14461 aagcaggcgc agctaaaatc atctttaact gaaacaaaag agaagttaga aatgatccaa
    14521 caaaacggga aaaagttcca agaagcatta gcaaaagaac agcctaaaat gtatcaatta
    14581 atgaatcaag tccagcagct acgtgctcgt aagaaaagcc ttcaagaaat ccaagaaaac
    14641 tattttggtt tttaccaagg ggttcgattg gtcttgcagc ataaacagca gctttcgggt
    14701 attgtcggag cagtggctga actgatcgat gttcctgcag atttcacgtt agctatcgaa
    14761 gcagctttag gtggggcagc ccagcatgtc atcgttgaaa atgaaaaaga tgctcggcaa
    14821 gccatcacgt atttgaaaca gcaaagagga ggaagagcaa cattccttcc actgacgaca
    14881 atcaaaccaa gacaattacc ggctcatata ttgacacaag cagcagctgt agaagggttt
    14941 atagggattg ccagtgaaca agtcagttat cccgatcaaa tccaaactgt ggttcaaaac
    15001 ctgctaggaa cgatcctttt agccaaagac ttaactagtg ccaatgcaat cgcgcaaacg
    15061 atccgctatc aatatcgagt ggtttcctta gaaggtgatg tgatgaatgc cggaggatcc
    15121 atgacaggtg gagcgaataa acgaggaaac caaggcagtt tgtttgtaca aaatcaagaa
    15181 ttgaaacagt tgactagtga atttgaagaa gcagataaac aactccaagc acaagaaaaa
    15241 aaagttcagg agctgcaaca agaaacagct cgtttagccg aagaacaaga agttttgcgt
    15301 acacgaggcg aacaattacg ttttgaagaa caagaagcga caaatcagct acaaaacatc
    15361 ataaatgaac ttgaacgttt tgaaaaagaa aagcaaatct caacttttga gacacgtgaa
    15421 ctgcagcagt ttatcgaaga ttacgaaaag caaacgaacg aattgaaaga caaacaaaca
    15481 gatcttgaat cgcaacgaca aaaaatcgac gaagaaatca aatcgttaag tcaagaaagc
    15541 gaccagatgg aagccagaag agcacaagta caaagtcaaa aagcacaaga acaagcagat
    15601 cttgctgtct tgaaagagca gtttaatcat ctgcagatcc agctccgcgg tgcccgagtc
    15661 caaaaagcag aggcaaccga acgtcaagaa gcgatagaaa agcagttggc gacattgaca
    15721 gcagactttt ctgatcatga agtcacagaa gaaagtttgg aaaaacaaat taacgaatta
    15781 tctgctcagc gagaaacatt aaaagccgag ttggcaaaag ccaaagagca gcgagataga
    15841 aggcaaaagg agatcgataa gcttgaagca gtcttggcag agcgtaatcg tgagcaaaaa
    15901 gcacgactgt cggaacaatc caaattagaa gtccaaaaag accgagctga aatgatttta
    15961 gataatcatt tgacctatct gcagtcagaa tatcagctga catttgagaa agcttcccaa
    16021 gactatcaag aaacaaccga tatcgaagac agtagaacaa aggtttcatc cttaaaagaa
    16081 cagattgaaa aactgggacc agtaaactta aattcaatcg aacaatacga acaagtcagt
    16141 gaaagacata cattcttagc aacacagcga gatgatctgt tagcagcgaa aaaccaattg
    16201 tttgaaacga tggatgagat ggatgatgaa gtgcggacaa gattcaaaga agtatttgaa
    16261 gctatccgtc aagaattcaa aattgtcttt ccaaatatgt ttggcggcgg taaagctgaa
    16321 ttagtactga cggaaccaac tgatttgctg aaaacaggta ttgagattga agtacaacct
    16381 cctggcaaaa aactgcaaag tctaagtttg ctttctggag gagaacgagc acttacagcc
    16441 atcgcgttgc tcttttccat tatccgtgtc tgtcctgttc cgttttgtat cttagatgag
    16501 gtagaagcag cgttagatga agccaacgtg aaacgttttg gtcgttactt gagcgatttc
    16561 caagatgaca cacaatttat cgtagtcaca caccgcaaag gaacgatggt cgcagcagat
    16621 gtactgtacg gagtgacgat gcaggaatcc ggtgtatcaa aaatcgtttc tgtacggatg
    16681 gaagatatca atgaagaggc gaaaatcaac gaaacgaaag tgtaggaacg aaaatgatca
    16741 aattagtagc aatcgatttg gacggtacat tattaaatga acaaaagctg atttcagatg
    16801 agaataaaca agcattagca caagcaaaac agcaaggggt caagatcgtt ctatgtacag
    16861 gacgcccctt agctgcgatg gcgcattatc tgcaagaatt aggactggta gatgaaggtg
    16921 actacagcat cactttcaac ggcggtttgg tacaaaaaaa tgatactggt gaaatcatgg
    16981 aaaagaaagt gatggaagta tcagatatcc aacgcttata caaactggct cagcaattgg
    17041 atctgccact agatgttttg tctgacaatg tggttttaca gctgcctagt gccccaagga
    17101 agcaatcctt gtacaatgtg ttgaataagc tgctgcaatt ccaaccagcg gatataagcg
    17161 atattacaga tgaatttgtg cttaataagg cagtaatcgc ttatgaccaa gaagaattag
    17221 atcctaaaat caaagaaata ccagcagaat tccatgaaat gtatgagatc atcaaaacaa
    17281 gaagtatgct tttggaattt atgccaaaag gtgttacaaa agcttatggt atttctttat
    17341 tggcaaaaga tcttggtttg aaacaagaag aaatcatggc gatcggtgat gaggaaaatg
    17401 atttaccgat gatccaatat gctggactag gcgtagcgat ggagaatgct gtgcctttcg
    17461 tcaaagaagc agcagatttc gtgacagcca gcaatgaaga aaatggcgta gccaaagtga
    17521 tccaaaaatt tgtattagag tagggggagt caaatgggat tttttgataa aatcaagcgt
    17581 gcttttactg gcgaagagaa aacagaagaa gttgaagtac aggagaagta cgacaagggt
    17641 ttagaaaaga cgcgtaaaac atttggtgaa cggatgaatg agttgtttgc caattttcga
    17701 acagtcgatg aagacttttt tgaagaatta gaagaaacac ttatcggtgc agatgtaggt
    17761 tttgaaacag cgatacgaat caccgaagca ttacgtcaag aagtgaaact cagaaatgcg
    17821 aaaaaatcgg cagaagtcca aaatgcgatc atcgagaaac ttgtggatct ctatgaagcg
    17881 gaaggaatca atgaagtaaa tgaactaaat atccaagaag acggactaac agttattttg
    17941 tttgtcggtg ttaatggtgt agggaaaaca acaagtattg gtaaacttgc ccatcagttc
    18001 aaaaacgaag gtaaaaaagt attgatggca gcagcagata ccttccgcgc tggagcaatc
    18061 gaccagttag ttgtctgggg cgaacgcgct ggtgttgaag ttgttcgtgg caatgcagga
    18121 ggcgatccag cagctgtcgt attcgatgct ttggaaagag caaagacaga gcaggcagat
    18181 gttttactag ttgatactgc aggccgactg caaaataaag tgaacttgat gaacgaatta
    18241 gaaaaaataa aacgagtaat ccagcgggaa ttaccagaag caccccaaga aacacttctt
    18301 gtattagatg caaccactgg tcaaaacgcg atggttcaag caaaacaatt caaagaaaca
    18361 acagatgtga ccggtcttgt tttgacaaaa ttagatggta cagcaaaggg cggtatcgta
    18421 cttgctatcc gtaatgaatt gcatttacca gtgaaattgg tcggtcttgg tgaaggaatc
    18481 gatgacttgg agccgtttga tccaaatgat tttgtcgttg gattgttcaa aggattacta
    18541 aaagaagaat aacccatgtc taaaaagcag gagctgtgac aaaagttgca gctccttgtt
    18601 tgaatgattg tttttaacat agctgtgttt ttgatgcctt catttttata cttatttgta
    18661 agcggttctc aaacaatttc gttctttttc ttagactttt tgattataat tagattcata
    18721 tgaattggag gtcacttaat gatgaatttt aagcaattat tattgcatgt caatgcgcgc
    18781 ccttttatcg accaagctcg atttggtata gaacgggaag gacagcgggt tgatcttgca
    18841 ggaaatctag caaaaaccga tcatccagca atctttggcg atcgatccta tcacccctat
    18901 atccaaacag attttagcga aacacaaaca gagatgatca cccctgttac cgattctatt
    18961 cccgaattat ttcagtatct cgctgctgtt tatgatgtga ctgctcgttc tataccgaaa
    19021 gaagagatga tctggccatt aagtatgcca cctgccttac cggaaaaaga cgaagagatc
    19081 attattgcaa aattaaaaaa tttcgaagat gtcttgtatc gacgttattt agcaaaaaaa
    19141 tacgggaagc gaaaacagat ggtaagcggt attcatttca attttgaatt tggcgatgag
    19201 ttgctaagaa cattgttcag ccatcaggaa gaatttcaag atttttccga attcaaaaca
    19261 gaactttatt tgaaaacagc gagaaacttt atgcgctatc gctggatgat cacttattta
    19321 ttcggtgctt caccaatgag tgagaagaac tactttttag atgaatcaca tccgcaagaa
    19381 cctgttcgca gtattcgcaa cagtgcgctg ggctatacga atcatccaaa tgtgaaagtt
    19441 tcctatgctt ctatgaaaca gtatttagca gatatcgagc gaatgatcga agaagggaaa
    19501 ctttcggagg agaaagaatt ttatacaccg cttcgtttcc gaggcggaaa gaaagtcgca
    19561 gatttagcaa caacaggtgt tcgttatatt gaattgcgga atatcgattt gaatccttat
    19621 gcaagattgg gtatcaatcc agagcaagtt cggttcttac aattattcct gatgtacatg
    19681 ttatggacag aagaaaaaga agactgtgac caatgggtag cagaaggtac gactcgaaat
    19741 aacaaagtag cactagaaca accatcagat caaacagaat ttcatcaaga aggtagagaa
    19801 attcttgaag gaatgaagca aatgctggtt gaattggatt ggttggattc tctttattta
    19861 gtagaggaag cattgactca aatggatcat cctgaacaaa cgttagcagc gaaactctat
    19921 caagaagcac agctatcgag tcagcaagaa gttgctgtgg cattgggaca tcaatattat
    19981 aaagaaagcc atgaacgtcc ctatcagttg gccggttttc gcgaaatgga actttctact
    20041 cagatattta tgttcgatgc catccaaaaa ggtgtccaag tcaaagtatt agatgagtcg
    20101 gatcaatttt tgcgtctgca attccaagac catgtagaat atgtgaaaaa tgcaaacatg
    20161 acaagtaagg acagctatat cgtcccactt atcatggaaa acaaaacagt aacgaaaaaa
    20221 gtcttaaaag aagctgggtt ccgggtacca ggaggcgcag aattttcatc catggaagaa
    20281 gcggtaaaag cttatccgag atttgccgag caggcatttg tgatcaaacc taaatcaacc
    20341 aattacgggt taggtatcac gattttcaag gaaggagcta gtctggaaga ttatcaagca
    20401 ggtttagcca ttgcttttcg tgaagacagt tcggttttag tagaagaatt tatgccggga
    20461 acggaatatc gtttctttgt gatcgacgga gaagtccaag ccatcatgtt gcgagtccct
    20521 gctaatgtta ttggtgacag tatccgaaca gtgaaagaac ttgttgaaga aaaaaatagt
    20581 gaccctttgc gtggaacgaa tcatcgtgca cctttagaat tgatccaatt aggtgaatta
    20641 gaacaattga tgttgaaaga acaagggttg acgatcgaat cagttcccca agccaatcaa
    20701 attgtttatc taagggagaa ctcaaatatc agtacaggtg gtgattcgat cgatatgact
    20761 gatgaatttt ctgaagctta caaaaaaatc gccgtttctg cggtagaagc actaggagct
    20821 aagattagtg gtatcgattt gattatacca gataaagaaa tcgatcctac aactgataaa
    20881 aaagcatatg ggatcatcga agcaaatttc aatccagcca tgcatatgca tgtttatcct
    20941 tttgcaggaa aaggcagaag attgacgatg aatgtattga aattgttata tcctgaagta
    21001 ttttaaaaga aaaagctttt gacagattgt cctatttgat gtcaatctga tcaaaagctt
    21061 tttttgcatg taaaaattta tgtgtttttt cgttttaaaa taaacgatcc cagaagcttt
    21121 ttttcttttt tggtttttct ttttcagctg gcgaagagtt ttcttctggg tatttttttt
    21181 cgatatcaat cacaggttca tttactgctt cttttgctgt taagagcaat ccgaattcct
    21241 caggatttgc agtgacgtaa tcgttgacta cagtgaaacg gctattgttt ttcgttgcta
    21301 gctggatata ttggttttgg acagaaaggg gtagagcccc attcaagagt atggaagcat
    21361 ctggatgttt tttgagttct tttaaaaagt tttctttgtt ttttggttgg atcatttcag
    21421 caacagtcat actaagatag cagcgttccc tgaatgtccc taaatattta tgctgttctt
    21481 cagggttcac taaaggtgta ccataaagtc ccttatccaa atggcttttt acatcatctt
    21541 gtgccataaa aaataccctc cttcttctct ttgtctttct tacgattata gcatattccc
    21601 aataatacct aaaacatatg aaaaagcggt tgcttttgtt caacgattca cttaaaataa
    21661 gaatgaaaat cattctcaat tagaaaggtg gattggatgc gctacggacg actagtagca
    21721 ttattagtta ttttaagtag tatttcattg ttcatcggag tatcgaatgt acaattgtca
    21781 gaactgctcc agttagatgg gcaaagctta caaatcttgc tagtgactcg tttgccacga
    21841 acgatttgtt tgatccttgt gggagcgacc agtagtattt gtgggttgat catgcaacat
    21901 ttgacccaaa ataaatttgt ttcaccaacg actgcgggca cgatggatag tgcgcgttta
    21961 ggtattttag tggctatgat tttcctacct ggtgcatcct tgattgtccg atccttgaca
    22021 gcattttgct ttgcttttgc aggaacattg ctttttttat cccttacgcg attgttcctc
    22081 cagaaaaatc aattgatgct tccgttgatt ggagtcatgt tagggaatat cattggttca
    22141 gttgctactt tttttgctta tcaattccag ttggtacaaa atatgacttc atggcttcaa
    22201 gggaattttg cgactgtgat acgaggaaat tatgagttat tgtatgctgt tgttccattg
    22261 ttgctcttgg tttggctatt tgcttaccga tttacgatca ttggtctggg cgaatcgttt
    22321 gcagtaaatc tgggaataga ttaccagaag atgcagtttt taggcattgg cttagtatca
    22381 ttggctagtg cagtcatgtt gatcatggta ggaagcattc cttttatcgg agtgatcatt
    22441 ccgaatcttg tctctagaat atatggagat caagtgcaca aaacaattgg cgtaactgct
    22501 ttagcaggta gtttgttctt agtattttgc gatcttgtcg ctcgcgtgtt gatttttcct
    22561 tatgaaatac cagtcagtgt gatcgttgga atcatcggtg gggctatctt cctttatctt
    22621 ctgataaggg gacgacgata tgcttaaaaa aaagccatct atttttattg gtatgcttgt
    22681 tcttgtttta tttgttacag gaatgtactt gacgatccat acatatggaa actggcattt
    22741 tgcatgtgca ttgaggagta agaaaatttt tgcatttatc cttgtctcgc tagctgtcag
    22801 cagtgccaca atcagctttc agacaattac gcataaccag tttttgactc cttcagtatt
    22861 gggacttgag tcgttatatg tccttgtcca aacggtcctt ttcttcttta tcggaggagt
    22921 gacgatgctt cagcagacag gtacagtttt tttcttattg aacgttgggc tgatggtcgg
    22981 gctgagtcta ttgttatttt tctttctttt gaaaaaaatg agagcgaatc tttttttatt
    23041 actgatgtca gggatgattt taggtacgct ttttggtagt gtcagtacct ttttacaagt
    23101 catcatggat ccgaatgaat atgatttgct tcaaggcaga ttatttgcaa gctttggcaa
    23161 tatccagagt cagtatcttt tgcctgcttc tttgatcatt atcggctgct ggtacctgtt
    23221 atttcgatat cgacatgtgc tagacgtttt ccatctcgga aatgaacaag cagtaaacct
    23281 cgggatagac acagatcgtt ttgaattttt gattttatgt tgtgtcagtc ttttgacagg
    23341 gacatcaacg gctcttgtgg gtccagttac ttttttaggg tttattgtcg caaatatcag
    23401 ttatcgtgtc ttttctactt atcgtcatgg tcagctattt atcggaagct ttctggtagc
    23461 tatgctgttt ctgacaggag gacagctcgc agtagagcag attttcggct ggaatacaac
    23521 agtgagtgtc gtcgttgaat ttgtcggagg aatttatttt gtcacaaaat tgattcgcga
    23581 aaggaagagt atcctatgat tgatttacaa aaggtcaata aactgtacca tggaaaatca
    23641 gtggttaaag atgtacagtt aacgattcct gaaaagaagt tgactgcttt tatcggtcca
    23701 aatggtgctg gaaagtcaac ggtgttgtcg atgatcagtc gtttgatacc aaaagataca
    23761 ggtgaaatct atttagacca taacgaagta aaggcttgga aatccaatga attagccaaa
    23821 aaattatcga tcctacgaca atcgaatgaa ataaatgtcc aaatcaccgt gaaagaatta
    23881 gtagaatttg gacgatttcc ttatacgaaa ggaaaattga cgacaaaaga cgaggaaatc
    23941 gttcaggaat cactggaaca ccttgggtta gaagaaatag cggatcaatc gattgacact
    24001 ctttcaggcg gtcaactcca acgtgcgtat attgcaatgg tgctagcgca agacacggat
    24061 tatattttac tggatgaacc tttgaacaat ctagatatga attttgcggt tcaaatcatg
    24121 cagattttaa aaaatttagt acaagaaatc gggaaaacaa ttgttattgt tcttcatgat
    24181 atcaactttg ctgcaagtta tgcagacgaa attgttgcaa tgaaagatgg acagttattt
    24241 acgcaaggaa cgacccaaga aatgataaaa aaagatgtat tggatgaatt atacgaaatg
    24301 gacatacgga tttgtgagat tgaaggccgc agattctgtc tttatttcta aaactaacat
    24361 taggagagaa gagatgaaaa aattagtagt aggtatcttg attctagcat catttggttt
    24421 agcagcatgt ggaaatagca acaacaccag tcaggcagac acaaaaaaaa gcagcacaca
    24481 aactgaaact acattgacga taacagatag taatggagac caaatcgagg tgccaaataa
    24541 tccagaaaaa gtcgtcgtat tcgacaatgg ttctttagat acgatggatg ctcttggtgt
    24601 tggagataag gtagttggag cagctacaag cagccttcct gagtatcttt catcctataa
    24661 aaaagtagaa tcagcaggtg gaataaaaga accagactta gaaaaaatta atcagcttca
    24721 gccagatcta atcatcattt ctggccgaca aagagatttt caaaaagatc taagtcaaat
    24781 tgctccgacc attttccttt ctttagatgc gaaaaatcca tgggaatctt tccagcaaaa
    24841 tgtcactgct ttaggggaga tctttggtaa gcaagaagaa gctaaaactc aattagagga
    24901 attatctagt gcaatcgatc agacgaaaaa gaaagcagaa gctactgaca aaaaagcact
    24961 agtcacactt gtgaatgaag ggcaattatc agcctacgga tctggttcta gattcggttt
    25021 catccatgat ttatttggct ttgaacaagc agatgatcaa atcgaagcat ccactcacgg
    25081 tcaaagtgtt tcttatgaat atgtgctgga aaaaaatccg gatatcttat ttgtagtaga
    25141 cagaacaaaa gctattggtg gagacgacag caaagatgat atttctgcca atgaactggt
    25201 agcacaaacg aatgctggta aaaatcagca gatcatctcc cttgaaccag atgtctggta
    25261 tttaagcggg ggcggtttag aatcaatgaa actgatgatc gaagatgtga atcaagcatt
    25321 taaatagcat aaataacaga ggattaaact ctcatactat gtaacaataa tgtttcttac
    25381 attcttaaat agcaagagcc tatcctcaaa gaagttatca aaaaccatcc gtaaaatcgt
    25441 attgatgatt ttacggatgg tttttattta tttgagaaat cttttttcaa cgtgaattca
    25501 ttatctacat catacgggtt gattctagaa tggggagtgg caaaaaatag tgtgatccat
    25561 tttttcagca tcaagatcgc ctcctttgat ttgaatcaaa ggtacaaagc gaaacttaga
    25621 taaaacttaa atttagatat ttttattttg taccgatctc ttctttaaac gatgttccat
    25681 ctgctgcttc tcggcaataa gtccactaga ctagaaaata tgagaagcta ttttctgtcc
    25741 agcgttctta ttactcaaaa caaatcgcag ttgtcacaat ctcttctaaa cgatgttcca
    25801 tctgctgctt ctcggcaata agcccactag actagaaaat atgagaagct attttctgtc
    25861 cagcgttctt attactcaaa gcaaatcgca gttgtcacaa tctcttctaa acaatgttca
    25921 atcagctgac cttcggtatt agctcaaagc actgatttca caacctctat ttaggcatgt
    25981 gtctcagcaa gcggttgata gttgatgatc tgcatttttc gataaaaatc ggcgggaagc
    26041 ttactccacc gttttagtaa ttgatagaaa taactctctt ctgctttgat tttatactcg
    26101 cttaatatca atccaaaact attcgttttt tttgaagcta attttttata aatatccaat
    26161 gctttggttt tatcttcatt gacaaagagt gtttttactt caatataaga accctcgata
    26221 ttttgtgttt cttcgataaa atagatgttt tttatatatt ccttcatagt gattcctcca
    26281 aagaagtctt ttatttgata agtttactct accgaagagt tgttaataat ccgtgaacaa
    26341 aaagtaattc tttttccaat agttgttaaa ggttttttat tttttatagt attttttgtt
    26401 atttaagaaa ggaataaggt taaacaaata acaggttgct ttttgggtct ttttccgttc
    26461 aagaaactga acgaagaaaa gggaaagttg tctcttttgt gataagagaa atcataataa
    26521 acgaatgact tactttccaa taaattgaga acagtcagaa ccagacaaat tagttgcatc
    26581 tgatgaataa agtgattatt ctatgacatg aggtgataca gatgaaatta gaagtgacaa
    26641 aagaagcaca agaagtattg aagaataaat tagaagcaga cgatcaactt ttattagata
    26701 tcgaaaacgg tgacggtcca tttgcagaaa gccaagtcag ttgccaattg gatacggcat
    26761 ttcgattgat cattgtcaaa aaagatacac aaacagatct aagtctttat tctgtagtgg
    26821 ctgatacacc agttggacca atcaaaatca aagacagtgc aatactttac atggatgatc
    26881 catccacact tgctttagaa ccaacttata atagtttaca attaaaagga ccaagcggct
    26941 tgagaaaagg caacttgcaa gttgttcgaa aagactagag ggataaaatg ggaaaattgg
    27001 cgatcatcag cgacctacat gtggacatca ataaattcgg cgaatcagag ctgatgcagc
    27061 tttggcaagt tttgcaaaag cacaagatca ctcggcttca tctagccgga gatacggcta
    27121 ataaagtaga ccgttgccta gctgttgtcg aatttttcgt caataaagga ttatctacga
    27181 catttcattt cggcaatcac gagttggcag atgtgcccaa tgaacagatg atggaccatt
    27241 ttccagaccc acatttttta aatgaacggt atattgcttt aaatgagcag accgttcttt
    27301 tagggatgaa tggctggtac gactatcagt tttccgaatt gaaagattac gaggcaatcg
    27361 tacgaatgaa gcgtttgtat tggtatgatc ggttcatcca gcgtgggaaa acagatctcg
    27421 aggtcaatgc agaaatgctt gcagctgcaa aaaatttgct agaccagctg gaagcaaaaa
    27481 aacttgaggt gattttatcc actcatttcg ttcctaaacg ggcatttatc atgtatcaat
    27541 ctgctcctta tgagcgttgg aacaaattaa atgcattttt aggatcagaa tcattcggag
    27601 aattacttga ccgttattca aatatcaaac aagtagtttt tggccatacg catcgtcgct
    27661 ttgaagataa atccatcggt cacacgattt acagctgcag accttttggt tattattatg
    27721 aatggcagct gacccgagat tttgtcttga aagaacagtt gctagacagc tatgatccta
    27781 tgaaattacg tgtcctcttg cgtgcccatc acccagcttt tcaggcctat caaacacaac
    27841 atttgcaaga ggaatttgaa caagcgatga caatcgttcc gtattgagac agcattagta
    27901 atgtgtaaaa gaaaatacct tgtaaaacat aaggataagt aagagcagta gatccattta
    27961 tcgtggatat gctgcttttt ttgcggaaaa taatcagcga atgtttattt gatcggatga
    28021 tttgtaactc gcagagtact agatgcaagc gtgtattctt tttttgaacg ataatcacaa
    28081 aaaaaaatat aatatacatt ttttatttaa ttataattaa tattgattga agtctaggca
    28141 gtcaagtcac attttgatag ataggagggg gacttacgaa ttattttaaa ggctatgaca
    28201 gctgtatttc tagattgtgt ttgcatcaag ttgcaataaa aactagaaat caaatcgggc
    28261 tgataatcat ttataactaa tcgatacata ggaccaaata taggtctatg ttcttttatt
    28321 tcataagtat cgtaaaacag aattttgcta tggattaatc caatcgactg atatgtttag
    28381 taaataaaga aagaggaatg tcaatgatga aaaaagaaat cgtattaaca gcagcaatga
    28441 tgttattcag catggtagca agtacgactt ttgtttctgc aactgaagta tacccaaagg
    28501 aatataacac agaaggaacg attacatttg aagcaggaga tgagggtgta actcctcctg
    28561 ttgatccaga gaatcctgat cccaataaac ctgtcgatcc atcagatcct ccaagccctg
    28621 gaacaggagg ggcattatcg attgattatg gatcaaaatt caaatttggg actcaaaaaa
    28681 tttctactgc ggataaaacg tattatgcag ctgctgatgt gatgaacgat gggtctagaa
    28741 aaccgacata tgtccaagtg acagatagga gaagtacctt atctgggtgg aaattaagtg
    28801 tctctcaacc agaacagttt aaaactgcca gtggggatga actagttgga gcacagctga
    28861 aatttacgaa agggcaggct gtttctttgg ttgatccaac atatacgccg caaacggtga
    28921 attctgaatt aacgttgaca ccgggaggaa acaatacgtt agcaattaat gctaaatcag
    28981 gaacaggtgt ggggacttgg gtctatcgat ttggtgcaaa tgaaaatgaa aatcaagatg
    29041 cggtacagct ttcggtaccc ggtaaatctg tcaagttagc gcaacaatat tccactaaat
    29101 tagtttggac attagaagat acacctaaca actagtttac tgaaaagaac tgttaaaaat
    29161 aaatacgtag tcatattgtc ttgcgaggta atcgagcaaa aattgtcaaa ggctaggcta
    29221 aatttgtttg gatacgaata gttcatctag gaatttaacg atcaggagga aaagatatat
    29281 tgaaaaagag gaggatcgtg ctcattttaa gcagtctctt agtgactaat atctttccga
    29341 tcatagggta ctctttggaa ttgaatcagt tggagcatgg aaatagaaga gacgaagaaa
    29401 gcaaactcac ttcgacattc gacagtttaa tagaatccaa ccagacacaa gaaagcagtg
    29461 aggatttaag tatttcgagt agtggagaga ccactgacaa cgtagaagct gagggttcgg
    29521 acaaacaagg actagaagat gcaccaattt ctgcggttga gctgcctgac gatcccaata
    29581 ttatttctat cgataaaatt tttcaaacac ctatcggtac tagcacgtcc atattggaaa
    29641 atgggaagtt actgcagttg aacccagcag aaaggtctca aagaggagct atttggtcaa
    29701 ataagaagat tagtttactc tcggatttta catttaaatc ttatttatac ttaggaaatc
    29761 aacgagatag agcgggagat ggcatgacct ttacattgac tggcgatcct agaatggcta
    29821 gtaatcccag tcaagttatt ggatcgccag gtatgggaat tggctcatat tctactcgtt
    29881 ctggccaacc ttacattgcg aatgcgctct cgattgagtt tgatacgtat aaaaatagtg
    29941 gttcttctga tcgaatggat cgagagataa ctgctgataa tagagggcat ggacatgtcg
    30001 cttttgtcac gcctaaacca aataataata attattctgg agagcatact ggcgtgacgg
    30061 tagctcctac atttctttct aatggcacat ggcgcttgtt aataattaaa tgggacgcgg
    30121 agcaaagaag tcttacttat gatttggaag gtgtcggtcg ctcttctcgg attatacctg
    30181 atctcattag gcagtttggt tctacagaag taaattgggg gtttacttct tcaacaggta
    30241 ctttttttca agaaaatgct gtcgctgtca cgcgacttcc atcgaatgtc acatcaacag
    30301 ctgatgtaaa agtcaacgat agtgattatg gggccatcgc tgaagctgga ggaaacgata
    30361 agataactat cagaaataca ttgaaggtcg agggggattt tcttgaatat aagaaaatgc
    30421 agactagtat cgacctccca caagaattaa ctattcccga gcatatcttg atcaatggaa
    30481 atcaaattga tgccaaagat atcttgataa ccggaaatcg agtcacgcta aatctgacag
    30541 attattttat tgctggagat acgttaataa tcgaattgga gacaactttg caggaagtaa
    30601 ttcctgaaaa agtactcact atgcattttg aataccttga aaacgggaat ttgattgagc
    30661 aatcgaatga aataaaccta aagatcgcaa agctgaagga gatagatatc catgtttatt
    30721 ataaagataa agacagtcag attgatattg ctgaaatgaa aacaatcact gggaaaatag
    30781 gagagaagta taaagaaact cctattgata ttgaagggta tgtttttgac tcggattcag
    30841 cgaatacaga aggcatcttc tccgaaaata cagaggatat ctatttttat tacagaaaag
    30901 gcaaacttta tctctcaact gctcctcaat atgtcaattt tggaaaacat aaaatatcca
    30961 gtagaccatt aagtgaattc ggacagtttt caggtgggtt gaaaattata gatgaacggg
    31021 cttttggaag ttggaaatta caattgaaac aagagaaagt tcttacaaat ggagattttg
    31081 agcttccaga agctctttcc tttgttacct ctgaaaatac aacggttata gggacatccg
    31141 ctgttacgat tttcgaaagt gatcaaaagg gtgaaagcga tttgtcctct cttttagatt
    31201 ctacagctca tcgtggaatc agaataaata ttcctgtaga aaaccaaaga atcggaacct
    31261 ttgaggggaa actatcttgg atacttgcag atgtcccagg aaattaacag gaagagaaga
    31321 atataacaaa attattgagt ttcaagaagg gcacaggtac cataggctct tgtgtcccac
    31381 agagacaaga ttttgttata gtcttctctt acatatgatt aaaggagcga ttttcttgag
    31441 accaaaacaa caattattta taacactcct agttatttta ggggcacttt ttaacaatat
    31501 atcagtgtca gctagtgcat ttaatttttc agtgacgccg ataacttcag agaatcaaat
    31561 cgacaagaga aaaacttact tcgatcttca acttgatccg gatcaggaag tagaagtaaa
    31621 agcggaattg agaaatgata cagaaaaaga agtgaaaatc gatatttctg tgaatagcgc
    31681 aaccaccaat tcaaatgtga tggttgaata cggaaaaaac gagattgaaa aagacatgag
    31741 cctgatcttt gatctggtag attatgtgag ctatccacag atagtgacgc taaaacctaa
    31801 aagtgtccaa accgttgctt ttcatgtcag gatgccgaat gagcgatttg atggtgtatt
    31861 ggctggtggg atcacattcc aagaaatcca gacggaaaag gaccaaacag aaactaagga
    31921 tcaaagctta tcgattgaga atgaatacac ctatattatt gctttgttga tgcaacagac
    31981 actgaacgaa gttgctccga accttactct tcatgaagtt aaaccagatc aaatcaatgc
    32041 aagaaatgtc atcttagcaa acgttcaaaa tgatcaaaaa acctatatca atcaagtagt
    32101 tattgaaaca aaaattacaa aaaaaggaca ttctgaagtt ttatatcaag aggaaaaaga
    32161 aggattgcag attgcgccga atacaaattt ttcttttcca actgctttaa atggtcaacc
    32221 gctaacccca ggtgaatatc accttacaat gactgtttta ggaaatgaaa atgaaaatgg
    32281 aaaattttcg agaaaaaaag gaaatactac gatcaactat accaatcaat gggtatttga
    32341 aaaagatttt acaatagacg gaaaagtagc caaggaattg aacacgacgg atgttacgat
    32401 taaaaaagac aataattgga tttatatctt agtagcttca cttttcttat tgtttatttt
    32461 attatgcata cttttgtttg ttttgagaaa aaaagaagag aaagaaaagt aaggttaaga
    32521 taacaaatag taaattttta ttattgtagg atggttgggc tctttttata acaatataaa
    32581 atataccatt ttattaataa aaatgcatac tagtaaatga tataattcta ataacaggtt
    32641 tgatcgcgag aaaggccaaa taaaacgctc tccaaaatgt taaaaaaaag acaggacgat
    32701 gtatattata caaacaagaa tcgctgacaa cagtgactcg gatccaggaa atcagtttta
    32761 tccccagcta gttggtgaat gcatggaaag taatatacgt agaaagagct gatgactaat
    32821 gaattatgag ttttttttaa gcaaagaaga tcacagaagt tattcattac ttaaatattt
    32881 agaagcaagc tcaaatttat cagagtcaat atcgaatgtt caagaagagt tgtcgctatc
    32941 gacatttctc ttgaaaaaaa cgatcgataa gctgaaacat gatttacaaa agttcgatct
    33001 agagaaaaat ttgcgagtaa ccgtcagtga attggatata tgtctggaaa ttaatggaaa
    33061 atgttctagc aaagctctgt tatctcgtta tataacggat tctttatcta tgaaaatggt
    33121 attggctttc tttcaggaaa aatatatctc agtagaaaat tttgctaaac agcatcacgt
    33181 gagttattct gtggcttata aagtattaca aagactaaaa agaaatctaa aaaaatatca
    33241 aatttttttt gaaaagagaa agtt
//
LOCUS       DAFLVO010000027        32385 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.027, whole genome shotgun sequence.
ACCESSION   DAFLVO010000027 DAFLVO010000000
VERSION     DAFLVO010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32385
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.027"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(12..482)
                     /locus_tag="L1U99_001307"
     CDS             complement(12..482)
                     /locus_tag="L1U99_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HBN1211858.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(641..1099)
                     /locus_tag="L1U99_001308"
     CDS             complement(641..1099)
                     /locus_tag="L1U99_001308"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBN1211859.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1270..2415)
                     /locus_tag="L1U99_001309"
     CDS             complement(1270..2415)
                     /locus_tag="L1U99_001309"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HBN1211860.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2428..3345)
                     /locus_tag="L1U99_001310"
     CDS             complement(2428..3345)
                     /locus_tag="L1U99_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBN1211861.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3773..4336
                     /gene="efp"
                     /locus_tag="L1U99_001311"
     CDS             3773..4336
                     /gene="efp"
                     /locus_tag="L1U99_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBN1211862.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            4437..4607
                     /locus_tag="L1U99_001312"
     CDS             4437..4607
                     /locus_tag="L1U99_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211863.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            4822..6081
                     /gene="lysA"
                     /locus_tag="L1U99_001313"
     CDS             4822..6081
                     /gene="lysA"
                     /locus_tag="L1U99_001313"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBN1211864.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            6068..6868
                     /gene="dapF"
                     /locus_tag="L1U99_001314"
     CDS             6068..6868
                     /gene="dapF"
                     /locus_tag="L1U99_001314"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBN1211865.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            6871..7752
                     /locus_tag="L1U99_001315"
     CDS             6871..7752
                     /locus_tag="L1U99_001315"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBN1211866.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            7749..8465
                     /locus_tag="L1U99_001316"
     CDS             7749..8465
                     /locus_tag="L1U99_001316"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBN1211867.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            8471..9166
                     /gene="dapD"
                     /locus_tag="L1U99_001317"
     CDS             8471..9166
                     /gene="dapD"
                     /locus_tag="L1U99_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBN1211868.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            9182..10183
                     /locus_tag="L1U99_001318"
     CDS             9182..10183
                     /locus_tag="L1U99_001318"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBN1211869.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            10180..11541
                     /locus_tag="L1U99_001319"
     CDS             10180..11541
                     /locus_tag="L1U99_001319"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBN1211870.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            11501..12652
                     /locus_tag="L1U99_001320"
     CDS             11501..12652
                     /locus_tag="L1U99_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBN1211871.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            12627..13796
                     /locus_tag="L1U99_001321"
     CDS             12627..13796
                     /locus_tag="L1U99_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBN1211872.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            13971..15350
                     /locus_tag="L1U99_001322"
     CDS             13971..15350
                     /locus_tag="L1U99_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBN1211873.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            15631..16428
                     /locus_tag="L1U99_001323"
                     /pseudo
     CDS             15631..16428
                     /locus_tag="L1U99_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            16617..17285
                     /locus_tag="L1U99_001324"
     CDS             16617..17285
                     /locus_tag="L1U99_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBN1211874.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(17485..17715)
                     /locus_tag="L1U99_001325"
     CDS             complement(17485..17715)
                     /locus_tag="L1U99_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211875.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(17842..19224)
                     /locus_tag="L1U99_001326"
     CDS             complement(17842..19224)
                     /locus_tag="L1U99_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBN1211876.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            complement(19380..20567)
                     /locus_tag="L1U99_001327"
     CDS             complement(19380..20567)
                     /locus_tag="L1U99_001327"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HBN1211877.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            complement(20574..21605)
                     /locus_tag="L1U99_001328"
     CDS             complement(20574..21605)
                     /locus_tag="L1U99_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBN1211878.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            complement(21651..23075)
                     /locus_tag="L1U99_001329"
     CDS             complement(21651..23075)
                     /locus_tag="L1U99_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1211879.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            23250..24155
                     /locus_tag="L1U99_001330"
     CDS             23250..24155
                     /locus_tag="L1U99_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBN1211880.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            24246..24923
                     /locus_tag="L1U99_001331"
     CDS             24246..24923
                     /locus_tag="L1U99_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBN1211881.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            24920..25090
                     /locus_tag="L1U99_001332"
     CDS             24920..25090
                     /locus_tag="L1U99_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211882.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            25204..26100
                     /locus_tag="L1U99_001333"
     CDS             25204..26100
                     /locus_tag="L1U99_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBN1211883.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(26155..27525)
                     /locus_tag="L1U99_001334"
     CDS             complement(26155..27525)
                     /locus_tag="L1U99_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1211884.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            27763..28509
                     /locus_tag="L1U99_001335"
     CDS             27763..28509
                     /locus_tag="L1U99_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBN1211885.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            28506..29345
                     /locus_tag="L1U99_001336"
     CDS             28506..29345
                     /locus_tag="L1U99_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBN1211886.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            29346..30296
                     /locus_tag="L1U99_001337"
     CDS             29346..30296
                     /locus_tag="L1U99_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBN1211887.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            30437..31189
                     /locus_tag="L1U99_001338"
     CDS             30437..31189
                     /locus_tag="L1U99_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211888.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            31208..32359
                     /gene="queG"
                     /locus_tag="L1U99_001339"
     CDS             31208..32359
                     /gene="queG"
                     /locus_tag="L1U99_001339"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBN1211889.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
BASE COUNT        10563 a         5888 c         6703 g         9231 t
ORIGIN      
        1 tttttattaa gttaaagaac ggattcaatt gcagcggtca ttttcaatgg agaagtttgt
       61 ggtgcaaatc gttcgattac tttgccattt ctatcaatca aaaatttagt aaaattccat
      121 tttattgctt tagtgacagt accaggagct tcatttttaa gataagtaaa aagaggatct
      181 gtattttctc catttacgtc aatcaattga tgcataggga aggtaacgcc ataagtggtt
      241 ttacaagctt ctgctgcttc agtcgctgaa tctagctctt gtttaaattg attggaagga
      301 aagcctaaga taaccagacc ttgtgtctga taagcttggt aaagttcttc taattgttta
      361 aattgaggtg ctagaccgca ttttgttgca gtgttaacaa tgattatcgg tttgcctgca
      421 tattttttca atgaatagac agtgccgtct tctaaagtag tttcaaaatt ataaatagac
      481 ataaagtttt ctcctttcta ttttatataa taaaaagagc gctaaactga aaactagcta
      541 tttgttttcc cgtttagaac tcttttcaga caataaatat ttaataaaat acgaagataa
      601 gatagctata ttgcttctca tctttacgtt cttttagaaa ctatgcttct acttcagacc
      661 attcatcgcg ttttgctaaa aattcacgag ccaaagcttg tgcaccttct agtgtatggc
      721 tggcagccca gccacattgt gtttcattgc ttgcaggtac ttcagtagct tcaagaacat
      781 ctttcattgt tgcttcaaga acatctaaaa tgtcttcgta gctttcatga ttcaatacag
      841 tcaagtaaaa gcctgtttgg catcccattg gagaccagtc tacgatgtaa tctgcgtgat
      901 tgcggattag ttcggcagtc aagtgctcaa gtgaatgtag acttggcatg tccatgtgtt
      961 ctttatttgg ttgtttaaag cggacgtcgt atttaatgat gacatcgcca tgcgcacccg
     1021 tttttcgatc agctacacgt acataaggtg ctttgacttt tgtatggtca agattaaaac
     1081 tttcgacatt cattctcatt tgtaagactc ctatctgttt gttcattcgt tttgatgctt
     1141 ttcactaaag aattatttag tgaaatttac aaaaacgtct ttctacttga ttctaacact
     1201 tatcgtttcc aaggtgtagc aatctgaaat attttttaga tttttctgct aagtcgttta
     1261 ttgggacttc tagttcttga ttctgtcaaa tgcctgagct aaatcgttta tgagatcctg
     1321 accatactca attcctacag aaagacggat caagccgtcc tttatgccag cctcttctcg
     1381 tttttctttt ggaatagacg catgagtcat gacagaagga atttccacta aactttctac
     1441 gccacctaaa ctttctgcta aagtaaatag ttggagtgat tcaacaaatg gaatagcaga
     1501 ttcttcattt tttaaagtaa aagaaatcat tccgctaaag ccgctcatct gctgcttagc
     1561 aactccatgg agttcatgat cgggtaatcc tggatagtag accttttcta ctgctggatg
     1621 agaaaataga aaatcagcta ccacaaaagc atttttttga tgttcctcca tacgaacact
     1681 tagtgtcttg attccgcgct gaagtaacca gctatcttgg ggaccaagta cggctccgat
     1741 agcattttgg taaaatccga tctgatcggc tagatcttta tggttagaag tcactaaacc
     1801 agctactaca tcgctgtgtc cgcctagata tttggtaccg ctatggacaa cgatatcaga
     1861 accgagatct aaaggtcttt gaaaataagg agtagcaaat gtattgtcag caataactat
     1921 caatccatgt tgatgagcca gagtggcact tttttctaaa tcagtaatct ttagaagcgg
     1981 attgctaggt gtttcaagat aaagtgcttt tgtattgggt ttgatggatt gttctatttt
     2041 atcaagatta ctcgtatcta tgatcgtgta ctcgagacca tttttagtaa gaactttgtc
     2101 aaatagacgg aatgttcctc catagacatc atctcctaat aagatatgat cgccagcttg
     2161 aaaaagagaa aaaacggcat gaatcccaga aagaccagaa gaaaaagcga atcctcgaac
     2221 accgccttcc aaatcagcaa tcagttcttc caatgcaaaa cgagtaggat taccagatct
     2281 tgaatattca tattgtttag gctggccgac gccatcttgc cgataagtgg atgtttgata
     2341 aataggtaca ctgacagctc ctgttgtggg atcttcactg atgcctccgt ggatcaattt
     2401 tgtttgaatg tgcatgtttc tttcctccta taagtaaatg ttttttgata aatagcggtc
     2461 tgctgcgtct ggaaaaatcg taacgacacg atgaccaggt ggtaaacgac gaatttctct
     2521 taatgctgct gcaaaagccg caccactcga acttccaact aatagtcctt gttctcgtgc
     2581 taactgccta gtatagttaa acccttctac atcagagatt gtctcgatct gattgattga
     2641 aaggggagaa agaaacggcg gaatgaattc tacaccgata ccctcaattt cgtgaggggc
     2701 tggatcacca ccatttaaca cagagccctc tggttctaca ccgattattc gaatgtcggg
     2761 atatttttct ttcaaaaagg tagaagttcc agcaaaggtt ccaccactcc caattcctgc
     2821 tacaaaacta tggatatttt ctttgatttc atgaaagatt tctggcccta acgtatgata
     2881 gtaagcagca ggattatctt tattttcaaa ttgaagaggc agatagctgt ttgatatctc
     2941 ctctgcaagt tttttacttt tgctgatggc accgatgatt ccttgctcac taggagaatg
     3001 gatgatcttt gctcccaatg ctttcatcaa ttgttgtttt tctaagctaa acttctctgg
     3061 aacaacaaaa accgttctta atttgtatgt gagtgcggcc agagcgatcc caattcctgt
     3121 atttccggca gttggttcga tgatcgtcgt tttttcattg atttttcctt gggcaaatcc
     3181 ttctttgatc aaataactgc ccaatctatc tttgatactt cctccaggat ttaaatattc
     3241 tagttttgca taaatagcag aacctttagg catagaatag tgctgattgt caaagcgata
     3301 aagcggtgtg gaaccaatag cttctgtaat tgtcgagata atcatgtggg cctcctaaaa
     3361 aaagataata aaaaaaggag ctgactatta aatcagctcc ttgaaagaca tagagaaaaa
     3421 ttgagtagat aaaaagataa gttacctggt actcattcta tgaagggcaa ttaatagaca
     3481 tgacaaatag tatgctgctt ttatgcacca tacaacagca acgattcaat tgtttttggt
     3541 tgctgactgt catgtgtatc cctccaagta aaatttttat taacgatagc atgaaaaaaa
     3601 ataaaagtca aaggcttgaa agaaaaaaat atttcgatag catcgtttac ccgtgtttat
     3661 ttttctgaca aataggcatg agaccttaaa agatagagaa tactctagtt ttctggccgg
     3721 ttgtctgata caataaagtt gattatgata aagaaaagaa ggagcaaaaa taatgatctc
     3781 agcaagtgat ttaagagccg gtatgacttt cgtacaagac ggcaaactga ttaaagttct
     3841 ggatgcaagc caccataaac ctggtaaagg aaatacagtt atgcgtatga aactgaaaga
     3901 tgtccgttca ggtgcaacat acgacacaac gttcagacca gaagaaaaat ttgaaaaagc
     3961 acatatcgac acaaaacctg tacaatattt gtacacgatg gatgatacag ctttcttcat
     4021 ggatttggaa acatatgagc aatatgaaat tcctgtagaa acagtagaag aagaaatgaa
     4081 atatatccta gaaaacatgg aagtaaaaat ccaatttttc ggtagcgaag tcatcggcgt
     4141 tcaattacca acaactgtcg tattacgtgt tgtggaaaca caaccttcca tcaaaggtgc
     4201 aacagtcact ggttcaggta agccagcgac aatggaaact ggcttagtag tcaatgttcc
     4261 tgacttcatc gaaacagatg aattgttgga aatcaataca gcagaaggtt cttatgtaaa
     4321 acgtgcgtca aaataattcg ctaacggatt gataagaatt tgaaaacaga gcttgacctc
     4381 ttgaaaggca gatcatcgga tctgcctttc aagaggtttt ttgtggaatc agcaaattga
     4441 aaaataaaaa agtatttgat tttatttata ttttgaaaga tgaatggcaa aagctagaga
     4501 aagaaaaaac tgcacttatt tatgaagaaa ttgaaatgat tcataaaatt gaaaatatcc
     4561 gaactattcc gaactatatt gaagcgaaaa tattttttca tcactaaata gtgttgaatt
     4621 tatgttttta tgtataaata gcttctaata gttcgggtat tttgttttta taaccatttt
     4681 tattcttatt tttaaaaaaa tatttcgaaa tatactagac aattcagaaa attttgttta
     4741 atattattcc aataaaattc aaatctttat caaatgaaat tccaataaaa acggaaaaaa
     4801 agtgaaaaga ggaatgaaaa aatgacagaa ttgataattg gcggagtcac agcaagcaca
     4861 ttggcagaaa agtataagac acctctgtat gtgtatgatg aagaaaagat gagacaaacg
     4921 atgctgtcat tcaagcgagg ctttgtatcg aaacgttttg atacaaaagt gctttacgcc
     4981 tctaaagcat tccaaacgat tgagatgctg catttagttc gtgaatatgg attcgggcta
     5041 gatgttgtca gtggtgggga aatctatacc gctttgcaag ctgattttcc tagagatact
     5101 atctacttcc atggtaacaa caagacgcca gaggaactga tctatgcact tgaaaatgat
     5161 ttgttgcata ttgttgccga taatttgatg gaagttgaat tattagcaga attaagccaa
     5221 cgctatttaa aaaaaatctg tatcatgctt cggttgaatg tcggagtaga agcacatact
     5281 catgaatata tcgtcactgc gcatattgat tcaaaattcg gcatgagcta tgaaagtaaa
     5341 gagtgccaac aagcccttca gttgataaaa gaaagcagct atctagagtt agaaggattt
     5401 catgctcata tcgggtcaca aatttttgat gttactgctt ggttagctga aatcgacaaa
     5461 ttgacgaatt acttaaccga ttttgaccaa cctctttcct tgaatcttgg cggagggttt
     5521 gggattcgtt atacacaaaa tgatcagccg atcccagtcg aagaggcact aaaaaaactg
     5581 attgaatata cggaagaagc tttggaaaaa cgaaaactga ccattcgtca attactgatc
     5641 gaaccgggta gaagtattgt tggagaagct ggtacaacac tatacacgat tggtttcatc
     5701 aaaaagacac cacataaaaa atattacttt gtagatggcg ggatgacaga taatatccgt
     5761 ccagctctgt atcaggcaga atacgattgt gatttagcag caaaactgtc ggaagaaaaa
     5821 acagagaaag tgacgattgc aggaaaaatg tgtgaatcag gcgatgtggt aattaaagaa
     5881 gcttatttgc cgaaagcaga atcgggtgat cttttagctg tttattccac gggagcttat
     5941 ggatactcga tgagcagcaa ctacaatcga gcgacacgac cagcagttgt ttttgtcaat
     6001 aatggccaat caagactgat tgttcgcaga caagcatttt ctgatctact aaggggggaa
     6061 gtttcctatg atccttcata aatataatgg ctgcggaaat gattttatct tattagatta
     6121 cgcagaagac acagattata gtcaattagc cgcttcttta tgcacaaaag aaaaatatga
     6181 tatagacgga ttgatcgccg taaaaatcga tccgttggaa atgatctatt acaacaaaga
     6241 tggcagccgc gcgccgatgt gcggaaatgg cattcgctgt tttgctcgat acgtaaatga
     6301 tcagaacatg atgaatgaac aggaattcaa cgtagagaca ttagcaggca caagaaaaat
     6361 tacggtgttg gatccctcac ctttttattg cagcgtagat atgggagtgc cagatgattc
     6421 tccggaaaaa atcaaagcta atcaaactta tccaataaaa aaccaggaaa tagagatcaa
     6481 tggtgaaaaa gtaacgatca ctagtttatt tttaggaacg attcataccg ttgtttttgt
     6541 tgaaaatgcg cgtgaggaag tctggagaaa aagaggtgaa ctgatctgtc atcatccttt
     6601 gttcaaagaa aaaaccaatg tcaactttgt agaagtagtc aatgaacaag aattgatcgt
     6661 ccgtacctat gaaagaggag taggttggac acttgcttgc ggtacaggtt gctgtgcctc
     6721 ttatgtggtt gctaaggaaa ctgggaaaat ttcagcagat caggtagttg ttcacttgga
     6781 acaaggagac ttgatgatct ctggtgagga tgcgatacaa atggctggcc cagcagttca
     6841 tgaatggaca agaatattgg aggaatgaag atgataaaag gttcgatcgt ggcgctgatc
     6901 acgccgatga atgaagaggg atcagtagat tatgctggtt tggaaaaatt gatccaattc
     6961 catttagatg aacaaacaga tggattatta gttttaggta caacaggaga atcttctacg
     7021 ctcacacaat ctgaggagga gcagatcctt caactgacag taaagaaagt ggctggccgt
     7081 gtgccggtga ttgcaggagc tggaacgaat aatacgaaag aaacgattga aaaagcgaag
     7141 cattttgctt ctttgggggc agacgcactt ttggtcatca ccccttacta caacaaaaca
     7201 agtgatgcag gactagctgc tcattttaca gcaattgcag aagcctcacc gattccgctt
     7261 attttgtata atgttccttc tagaacaggc atgtcgattc caatccatgt attagtaaat
     7321 ttagcagaac atcctaatat cattggtttg aaagaagcct caggagatat ggcttatgtg
     7381 atggatgccg ctcggttgat tggagaagaa ttcttccttt acagtggaaa tgatgatttg
     7441 atcctaccag taatgagtgt aggaggaagc ggtgtaataa gtgtatgggc gaatatccaa
     7501 cctaaaatag tccatgaatt agtaaaagat acgcaggacg gaagatggca gcaagcaaaa
     7561 gaaaagcaat taaatgcact tgaactgatc catgccttgt tcagtgagac caatcctatt
     7621 cctgtcaaag cagccatgtc attattagac ttaccttccg gacctctacg cctgccttta
     7681 gtttctcttt caaaagagaa aaagaaacaa ttagctcagc ttttgttaaa agaaaggacg
     7741 gttgaaaaat gaaaatcgga ctgattggca gtggacagat gggaaataga gtcgaagaag
     7801 ttgcacaaga aagaggagat acggtccttc ttttacggac ggcacctaaa gaagcaacta
     7861 cgcttgcttt tacggaactg ccagaactgc ttattgattt ttctcatcca gataatttag
     7921 agaaaatcct ttcgtatagc ttatcatatc aacttccgtt agtcattggc acgacaggtt
     7981 atacacaatc acagttccaa gaaataaaag aacatgccaa acatgtacct gtgatgtata
     8041 gtgctaattt ttcgttcggc atcatggtga tgaatcaact aatcaagcaa gcagctgcaa
     8101 tgttgcaagg ctggcagatc gaactgattg aaaaacatca tagtcgtaaa aaagatgcac
     8161 catctggtac tgcaaatatg ctgcttcaaa caatccaaga agtgcaaaag ctgcagcccg
     8221 tatacaactg gcaagggaaa aaaagagaag aaaaccaaat tggtgtacac agtattcgtg
     8281 caggttcttt acctggtgaa catgatgtat tgtttgctgc tactgatgaa atatttacga
     8341 tcaaacatga atctttttct aatcgaatct ttgctgcagg cgcagtagaa gcagcggact
     8401 ggttgaaaga tcagtcacca ggttattaca aattagaaga tttattaatg gacaaagggg
     8461 tgtaaaaaac gtggaagctc aagaaatcat ccgctacatt caaacggcat ctaaaaagac
     8521 gcctgtgaaa gtctatctga atgtaaccga gccaatcgaa tttaaagaaa gtaaagtttt
     8581 tggtgaagga agcagcttcg ttgtttttgg tgactatgag acgattgctc cggttttaga
     8641 agctgaatca gaaaaaatca ttgaaatcga aatcgaaact gctgcaagat acagcgcagt
     8701 tcctttgcta gatattaaaa aaattaatgc tcgtatcgaa ccaggtgcta ttatcagaga
     8761 tcaagtgtca atcggcaaca atgccgtgat catgatggga gcgattatca atattggtgc
     8821 agtaatcggt gaaaacacga tgattgatat gggtgctgtc ttaggtggac gagcgacagt
     8881 gggcaaaaac tgccatattg gtgcaggagc tgtcttagca ggtgtgatcg aaccagcatc
     8941 ggccaaaccg gttatcgtag aagacggcgt actggtaggt gcgaatgcag tgattgttga
     9001 aggtgtccat atcggaaaag atgcagtcgt ggcagcagga gcagtggttt tagaagatgt
     9061 ggcagcagaa actgttgtcg gtggaatacc tgcacgtgta ttaaaaataa gtgatgatca
     9121 gacaaaagaa aatacagcat tgattgctgc gttacgcgaa ttatagagga gatggagaaa
     9181 aatgcgcgaa atagatacct gtattgtggg ggcaaccgga ttagtcggcc aaacgatgct
     9241 caaagtgtta gaagaatatg attttccagt aggacgattg aaattattag cttcaaaacg
     9301 ttcagccggt aaagtttgtg tattcaagaa aaagaaacac actgtacagg aattgacaga
     9361 aacttcattt gaaggatatg atttagcgct attttctgca ggtgcttctg tatccaaaga
     9421 gtttgcgcca atcgcacgaa gtcagggact atttgtcata gataattcct cagcatggcg
     9481 ggaagattcg gatattccat taatcgttcc agaggtcaat ctggaagact atacattgaa
     9541 tcggctgatt gcaaatccaa attgttcaac cattcaagcg gtacttccgc ttaaagcttt
     9601 acaagaagcc tttggtatcc agcgagtcaa ttattcgacc tatcaagcag tttctggttc
     9661 cgggcaaaaa ggcattgaag atcttcatcg tacgcaaaat gacgaggaac cagttttgta
     9721 tccttataat attagccaaa cggtgattcc ggaaatcgat cagcctttgg aaaatgggta
     9781 tacaaaagaa gaacagaaaa tgataaatga gacccgtaag attctgcatc agcctgcttt
     9841 gccagtatca gcaacctgcg tacgtgtgcc aatcgaaaat ggacatggag tctctgtggc
     9901 agttcaactg caaaaagagt ttacgacgga agaaattaga gagtgtctca gccagtttcc
     9961 agggattcaa ttagaagatg atctagcagc acataaatat ccgacgagca ttcttgctag
    10021 aggaacagat atggtttatg ttgggaggat cagaaaagac acttctttag agaacggatt
    10081 gttgttctat acgactgccg ataacatacg caaaggagcc gctgcgaatg ccgtacagat
    10141 tgctgcagct ttaatgcaga aaatagcgga ggtggcaaga tgagtaatac gctgaaagta
    10201 gcgaaattcg gcggaacatc gatgtctcat gaagagcaat tcaaaaaagt ccgtacaatt
    10261 gttctttcag atcccaatcg ccaagtgatc gttgtttctg ctttaggcaa acgtacgtca
    10321 gatgatgaca aagtaacaga cttactttat ttgatttatg cttaccttca gcatcatgtt
    10381 gattggacac ccctttggaa aaggatttgt gatcgtttca ttcaagtaag agatgttctt
    10441 gccctgcagt tacctattga agatgaacta gcacgcatac agaaacaact ggaagacgaa
    10501 aagataactg aagattattt agtaagtaga ggtgaatatc tgactgctca actgatggct
    10561 gagtatcttg gttaccagtt tattgacgca aaagacctga ttttctttga ctatgatggg
    10621 aaaatcgatc aggaaaaaac agcacaggaa atcacaaaag catttaaaag atatccgaaa
    10681 atggttgttc cagggtttta cggggcgaac cctgcaggaa aagaaaaatt attgggccgt
    10741 gggggaagcg acattaccgg cgcgatactg gcgaagatgt tgcaagcgga aagttatgag
    10801 aattggacgg atgtttcagg aatcatgatg gctgatccgc gaatcatcga tcatcctaaa
    10861 atcatcgagg aaatctcttt tagagaactg agagagatgg cttatatggg ggctaacgtt
    10921 cttcatgaag cagctgtttt cccagttcaa gaggctgata tccccatcca aataaaaaat
    10981 accaatgatc ctttcgctca agggacaaaa atatcgaatc acgaaataga aaaggaaaat
    11041 ggactgacag gaatagctgg acgcaaggat tttctttcca tcactttatt caaacgtcat
    11101 atgtccgatg aaatcgggtt tatctggaaa gcaatgagca tttttgctaa acatgagata
    11161 tcaatcgaac atattccttc agggatcgac aatatcggag tgatcgtctc agcagaagcg
    11221 attgccgata agttatttct catcacgaaa gaattaaaag aaacacttgg cgtggaagaa
    11281 atcgtcgtga tcgaagactt agctttgatc tctgtcgttg ggggtccgca taaagaattg
    11341 attggattat ctgggaaagt gttatcgata ttgaacaaat tagaaattcg cacatcgatc
    11401 ttatcacaag gagcacagga gttgaatctg atcatcggtg taccgaataa tcaatatgaa
    11461 acagtagtga agggtatcta tgaagggatg gtgaatacgg atgctgaaag aatatcgaat
    11521 ggcactccat caaattcctg aaatcgggtt tcatgaattc aagacaaaaa aatatttata
    11581 tgaacaagta aaaaacagcg aggccgttat ccatgaaatc ggcgaaacag gactactcct
    11641 ttattttgat aatcagcaag aagaaacgat tgcttttcga acagatatcg atgcactgcc
    11701 agtcaaagaa gaaacgaatc tctcttttgc ttctaagcat gaaggttata tgcatgcatg
    11761 tggtcatgac ggacatatgg cgatgctttt agggttgact gactttataa ctaaacacat
    11821 tgaggatctt atttataatg tagtactgat ctatcagcca tcagaagaaa tttccggtgg
    11881 cgcacaaagc gttattcagt caggattgtt ggataaatat gaagtacaag caatatttgg
    11941 ctttcatcta tggcctggac tagctaaggg agaagttttc tctcgaccag gacctttgat
    12001 ggcacaaagc agtgaaacag acattatcat taaaggccag tctgcacata ttgcttctag
    12061 tgaaaaagga atcgatagtc tggaggcagc tgtacgattt ttgaagaatg tttatgattt
    12121 tgaccggcaa ttaccggcag agtggaatca tctaatgaaa tttggccaaa tccaaggtgg
    12181 aacgatccga aatgttttag ctggagaagt tattgtatcc ggaagtatcc gttcttacag
    12241 ttcagatatg caaaattatt tgaagagggg attagaccat ttagcagaac agtttcactc
    12301 tacagctact atttcttttc gctataatga cggctatcca gctgtaatca accatagagg
    12361 cttatatgca gcactgttag attcaaacaa actacatgaa ttagatgctc cagttcttca
    12421 agccgaagat tttggcatat atacgcaaca atatccatgt gtatttttct ttttaggtgt
    12481 cggtgatacc cctgctttac atgatccgac gttcgatttt gatatggatg ttttagaaaa
    12541 tggtgtagaa tggtacaaaa cgattctttt tacagaaaat cttcttgtaa aaatcgatag
    12601 cagttcaaaa gaggagcgag taaataatga tgaatttatc caatcgattt agtcctaggc
    12661 tttctagaat agaagtatca aaaatacgac aattcgatca gcaaatatcg tcgataccag
    12721 atgtgatcaa actcaccctg ggagaaccgg attttccaac tcctgaacat gtcaagcaag
    12781 caggaatagc agcgattgaa gaagactttt ctcactatac cggaatgaga ggattagagg
    12841 aactgcggga agcggcttgt atatttcagc aacagcgtta tggattaact tatgatccgc
    12901 aaacggaagt tttgacgaca gttggtgcaa cggaagcgat tgcctctgcg ttgttatctg
    12961 ttttggaaga aggagacaag gttcttattc cagcgcctgc ttattcagga tatcagccat
    13021 tagtggaact agctggtgct gaattgatcc cgatagatac ttctgacaca gggtttgtct
    13081 gtcagccgga acaatttgaa cgagcatttg aacaatatgg atcagctgtc aaagcagtca
    13141 ttttaaacta tcctaacaat cctactggga cgacattgtc tgcaaaacaa ttgaaagcaa
    13201 tcgctgaggt tttaaaaaaa tatccggtat ttgttataag tgatgaagta tatgctgaat
    13261 tgacttatag tggaacgcat atgtccatag ctacttatct tccagaacaa acaatcgtga
    13321 taagcgggtt atccaagtca catgcgatga ctggttggcg agtgggcttt atttttgctc
    13381 aaaaagccct tattgacgaa ctaattaaag tccatcaata tctggtgact gccgctacaa
    13441 cgatgtcgca aaaagctgcg gctgaagcgc taataaatgg ggtgaaagat agcgagaata
    13501 tgaaagagca atatcaaaca cgaagagact atctggtcca gcaattggcg cctttaggat
    13561 ttgaagtgac ccagccaaac ggtgcatttt acttgttttg caaactccca gctgccattc
    13621 aaactgactc ttggcagttt tgtgtagaat tagcggaaca ggcaaaagtt gcgtgtatcc
    13681 caggaattgc atttggccca gaaggagaag gttatatccg gatttcttat gctagcagca
    13741 tggaaaaatt acatgaggcc tgcaaacgga tcaaagactt tttaacagaa cagtgattca
    13801 tagattttat caaaaaaaca atcgttaatt ttgcggtata ttctgcaagg agacgattgt
    13861 tttttaaatt tagttcaaat gaacgcgttt cttttgattc ataactaatg taatgttaag
    13921 tttaaattgt ttagaatgat tttaaaagaa tattcaagga ggtttcatca atggaaaaaa
    13981 tcaaagttgt cattgtaggt gcatctcatg gagggcatca atcgatcttg gaactattga
    14041 cacgatacgg tgaaaatgta gatatcacgc tatttgaagc aggagactat atttccttca
    14101 tgtcatgtgg tatggagctg tatttagaag acaaggtaac agatgtaaat gatgtacgta
    14161 atttcagacc agaaaacttt ccgcaatcca atgttcatat tttaaataat cacgaagtaa
    14221 aaacgatcga tgccgataaa aaaacagtaa cggttactag cgcatcagat aacgaaacaa
    14281 aagaatatcc ttatgacaaa ttgattttga gttctggtgt caaaccaaac aatctgccag
    14341 taccaggagc agatctagaa aatgtctact tgatgcgtgg atacaattgg gcaaccaaaa
    14401 tcaaagaaaa attaaatgat ccggctatta aaaaaatcgc tgtcgtaggt gcgggttaca
    14461 ttgggatcga agcagcagaa gcaagccgaa aagctgggaa agaagtcgta ttgcttgatg
    14521 tgatcgatag acctttaggc acttatttag atgctgagat gacagatatt ttagaacaac
    14581 acctaaatga aaacggtatt gaagttttga caaatgcaaa aatcgaagct tttactggta
    14641 acggaaaagt tgaggcaatc aaaacaagtg aaaaagaaat cccagcagat ctagtcattc
    14701 aagctgccgg tgtgaaggca aatacagaat ggttaaaagg gatcgtcgac ttagatgaac
    14761 gtggctggat ccaaacaaat gaatacttgc aaacgaatct tccagatgtg tatgcagtag
    14821 gagatgctac acttgcttat tctatcccag cacgcaaaaa aatgccgatc gctttagcga
    14881 ctgttgcacg tagagaagca cgttatgtag taaaacatct ttttgaagaa gtaccaaaca
    14941 aaccgttcgg cggagtcgta ggttcctctg cattaagtgt ctttgactat cattttgcag
    15001 caagcggatt gaatagcttt acagcagcaa aagcaggagt agatgtacga gtgtcttatt
    15061 atgaagatac gttacgacca aaatatgtac cagaagaaca aggaaatcca aaagtgtcca
    15121 tccaattatt ctcggatcca atgacccatc aattgctagg aggagcagta ttatctacct
    15181 atgatgttac aggtcaagga aatgtattgg cactagcgat ccaaaacaaa ctgactttag
    15241 aagaactagc agaagctgac ttcttcttcc agccaggctt tgaccgacaa tggagcatgt
    15301 tgaatctagc cgctcaacaa gcgttaggag aagaaccatt tgtagaataa gaaaacgaaa
    15361 tatttgaaaa gaggttgtga aaaagctgcc ttgcatcaag taataagaac agccaagtaa
    15421 aaacagcttc ttatgttttt aacttggctg gacttattac cgcagatgca agcttttgaa
    15481 caccgtttat tttcaaaaaa gggactgtga cacgatttgt gtaccgaccc ccaaaagtta
    15541 gaccaaaaaa tctaactttt ggaggtcggt attttttatg gttaaatata cttttgaact
    15601 taaattaaag atcgttcatg attatttgga tggcaaaggc gattggaccg taaaaatcca
    15661 gatcaagaga ttgaagcgga aatgcttaaa attcgggaga agcacaagga ttatggctgt
    15721 ttacggatga ccaatgaact aagaaaccgc ggtttctcta tcaataaaaa gaaagttcag
    15781 cgcttgatca agaagctagg aataaaagta acggcataca cgcgtaaatc acgtcgctac
    15841 aattcttatc gaggaaaagt tggagcagta gccaaaaatc ggatccatcg tcgtttctac
    15901 accagtatct gccatcagaa aatcacgacg gatacaactg aatttaaata ccatgaagtg
    15961 gatgccaaag gcattatccg tcaaaagaaa ttgtatctag atccttttat ggatatgttc
    16021 aatagtgaga ttttatccta tcgtatctct gaaaagccca atgcattagc ggtaatggaa
    16081 ggtttggagg aagctatcca gaccactaac gattgtccct atcgtcgtac gtttcactca
    16141 gatcaaggtt gggcgtatca aatgaaagct tatagaaaca aattgaagga gtacaaaatc
    16201 tttcaaagca tgtctcggaa agggaactgc ttagataatt cacttatgga gaattttttt
    16261 ggcttattaa aacaagagat ttttcacggg aaagtttata actgtttcga ggaattaaaa
    16321 tcagccatcg atagctatat ctattactac aataatgaac ggataaaaca gaaattaaac
    16381 tggcaaagtc tcgtccaatt tcgtaaaaca accgtaacgg ttgtgtaaaa atatcatttt
    16441 agagcataaa aaaaaggagt ggatttctcc actccaaaaa agtctaactt ttgggggtca
    16501 ctacagtgtc acagtccttt ttttagtaaa aggatacatt tcttccttgt atattccatg
    16561 cgtgttcgtg agaaagcata tataatttaa ttaacagata gttaggggga gaaaaaatga
    16621 ttttttcaat tacaatgaaa ctggtgttcg ggttgatcgg tttattatta gtggtacgtt
    16681 tgcttgggaa gaaatccatg tcagaaatca caccgtttga tttagtctat acgcttgttt
    16741 taggtgggat cttagaagaa tcaacctatg atgacaatgt ccatgtaggg catgtcctat
    16801 ttgccattgc gctttgggca gtaatgattt atggtatcga acgtatcgtc caaaaaaatg
    16861 aaaaggtcaa tcgttgggtc aaaggcgagc catctgttct aatcaaagac ggcgtcatca
    16921 acatgacaga gttgacaaat aaccatatcg agatggagca gttgcgagca atcttaagac
    16981 agcaagaatg cttttttctt gaaaatgcca aacatgttat cctagagaat gccggtcaaa
    17041 tgagtgtatt gaaaaaatca gatgaagaca aagctttatc gatcctgctt gtagatgaag
    17101 ggcaaattca gcataaagtg cttcagtcca atcaattgac tgaagcatgg cttatggaga
    17161 acttgaagaa agaaggctat gcagatgtaa aacagctgat ttatgttgaa tggtcagaag
    17221 aaaaagggct ctacatacta aataaagaag acgtcatgca tgaatcttac cgaatagatg
    17281 gatagataga cagaggttgt gaaatcagcg ccttggcttg ttactcaaaa ctaagcgact
    17341 ttttcacaac ctctgatatc taatatacgt tgttccagaa gttgcttctt cgaaaaataa
    17401 gccaaaattc cacaaaaatt taagaagcaa ttttcgaaaa atcctttctt attttttgaa
    17461 gttgatcact tctgtcacaa cctctcatgt cacaaaccat ttttttgttt cctttaactc
    17521 aatataccgt acgtcttccc acaatatcgg ctgatggtca atcataaagt aatcttcata
    17581 ggcttcacca atgaagtgcc cttcgacctc atccaagagt cttccaaatt catcttttaa
    17641 attgagctga atgattactg ctttacgaga taaaaaggct tctgtcagta tactatcgat
    17701 ttcttgcaat gtcatttgtt gtttaggaag aggctgtttg cgtgcttctt cttcattttt
    17761 ttgataccgt tgactagttc ttccatcgca aaagcagtcc cccattttaa tccaaatggc
    17821 cgatctcgat actcgttata gtcaatgaat ttttttgctg tccgtctcat cttttccacc
    17881 ttctaatcca ctcataccac ctgcatgccc gccaacgaga gaactacgtg cgatggcgcg
    17941 tcctccttgc aagagactat gcgcatggat gattgattga aagccgtatt tttttctaat
    18001 cgtatcgaca acaaaatcaa ctttcgcttc atttatctgc ttttcaggat cttcaaaaag
    18061 gttaagctgt aaacctgtcg cgtatacgag gtcggaacag ttcacgccta cacgccgaat
    18121 atcctggtag tggtaatgct ggtggaaaat ggtcaataaa gcatctgcaa gatctctgct
    18181 agcatttgtc gcttcgattt tcatttgctg gtgaaacccg gtcttgccat ttggatcaag
    18241 atagcctaaa gagtatccta cccataagct gactacttgt gtttttgctg cagatcgtct
    18301 caagcgagtg ccgacttggt cggccatttc tttgataacg atctcgattt cttctcgtct
    18361 tgtataatct ctatctagga tttgactatt tccgatactt tttgattttg gtgtatattc
    18421 ttgtcccaaa aaacttcgat cgatgcccca agcatgggca taaagctgag taccgatgac
    18481 ccctagcttg cttttcaagt gataataatc cgcgtgagct aaatcataaa cagaatgtat
    18541 acccatttgt ttcagacgtt ttgctgttcg tttgccgatt ccccaaaagt cagtgatatc
    18601 tgagattttc cataactttt ctggtacatc ttcataacgc cattcagcaa acatttgctt
    18661 tccgtctttt gagccattgt ctaaggctag tttagcaagt agcgggttat cgccaattcc
    18721 tatagtcgtg tagattccgg tctgctcaaa cacatcttta tggatcagtt tagccatgtc
    18781 gtacgcattt gttttaccaa agagtgccat gctatttgtt acatcaagga agctttcatc
    18841 gacggaatag acatgatggt tcgcttcgtc tgcatatttt ttatagatag aattgatttc
    18901 tctgttcttt tccatataat aggccatcct tggggcaaca atatataaat cacttggata
    18961 ggggaaggga agatctctgg cacggctgat attggtgatg ccgtaagctt tttttgctgc
    19021 aggactggaa gccaagatta atccgctacc ccgtgtttct gtcgaatcgg acggatagga
    19081 catgactact aatttagttg taaggggatc aagatccttt tcaacgcact ctacggaggc
    19141 gtaaaaagat ttgcagtcaa tacataaaat atctcttgaa ggttcttttt cataaacaaa
    19201 taccggattt tgattcgccc acataacaat cacctcttca acacaattag aacacacgtt
    19261 ctctttccgt gtcaataaaa aacagcaatt ttcaaatacg agcaaaaggc tcacatttgg
    19321 aaattgctga gaggttattt ttatctattt gtttttagct gagatcgttg atttttttat
    19381 caaacatgaa cagcttctgg atcgatcttt gttgtcccat ttccaatgtg tgcaacataa
    19441 aattccggag catagccgac aactttcatg tattcatcat agacattgtt tttgaaggca
    19501 ggtatatttt cttctttgac aagagcaatc gcacagccac caaatccagc tcctgtcatt
    19561 cgtgcaccta agacaccttc ttgtttttga gcagcatcta ctagtgtatc taattcgatc
    19621 ccagttactt cataatcata gcgaagagag tggtgagaat catttaacag ttgaccaaat
    19681 gcttctaagt tcccagcttc taattcagct tttgccttca aagtccgctg attttcagaa
    19741 acggcatggc gagctctgcg tatcaatgta tcatcgccga tttggtcaat agttgattca
    19801 aattcttctt catctaagtc tcctaaagaa gagataggca aagttttttg caaacgtgcc
    19861 aaggcttctt cgcattcgct acggcgttca ttgtattttg aatctgccaa ttcccgccgc
    19921 ttattcgtat tcatgatgac gattgcataa ccatctagtt tcactggaac catttcgtat
    19981 ttcagcgtat ttgtatctaa taagattgca tgatctagct caccgaagcc gatggcaaac
    20041 tgatccatga tacctgaatt gacaccgatg aattcatttt ctactttttt acctgtttgg
    20101 actagttcca agcgatctgt ttttaaatca aacagatctt ctaatacaac acctactaat
    20161 aattctaatg aagcgctact ggaaagtcct gcaccattag ggattgttcc ttccactaat
    20221 aactcaaacc catgatcgat tgagtgtcca gcttctttta atttaaggac cattcctttt
    20281 acgtaatttg cccagtttgc ttttttatca tattctagct catctaaagt aaaactaatg
    20341 acaccgatat cgtcaaagtt tgtggaataa actaatattt tattatcgtc tcgaggtgct
    20401 gctacacctt gcgttccata agtgatggaa gcggggaaga catggcctcc attgtaatct
    20461 gtgtgttcac caatcaaatt gatgcgtcct ggtgagaagt attgtgtagt ttttttaggt
    20521 ccgaatgttt cggcaaattt tgtgtttaag cttcttttga tttccatgat gagttattcc
    20581 tttcttgttt tgattttgaa ttctgttact gtttcaaata ctgatccggc ttttaaatga
    20641 atcgaaccaa atgctgagaa gcgctctgca cctggagctg tttgagtctc aaatgtgatg
    20701 ccaccgtgat gtgccagttt tcggttgcgc atttctggtg tttctgtgcc gaaatttgca
    20761 gtgaaaataa ccacactaga agcatctgta gcaatatcta cttggattct tttatcgggg
    20821 ctagtcaagc gagcggcttc tttacccaag ccggtttctt ttaagaaaaa tggatgatcg
    20881 attccgtcaa caagattttt ttgatccaaa tcactagcaa aaacggacgc taatttttta
    20941 ggtatttgaa aatcgaaagc acttcctgca gcattttctt ttacccctat aggaatacta
    21001 tctgttcgca aaggagcata agcttcgcta ttgagccaaa gctcatgttg atcgattgac
    21061 tgagaagcat ctcccgtcaa gttgaagtaa acatgatttg tcggattgaa taaagtatct
    21121 tggtcactgg tgccgcgaga ggtcactcgc cagatattat cttttgtcaa agtatagcgg
    21181 atttccacat ccattgtacc tggaaaacca tgttctccgt cgggacttgt agtagtaaaa
    21241 atgacagaag cttcattttc gccattcaaa atgacataag accatttttt taattcaaat
    21301 ccaggagcac caccatgcag attatgtcca gtttttggat ctgtggctaa ttggtaagtt
    21361 tttccattga gagaaaagcg gccattttcg attctccctg cggtgcgacc gatagaagca
    21421 ccgatatacg gatctttttc gatatattct tcagcggtgt caaatcccaa aactaattct
    21481 cgatcatttg attttaaact gacgattcta gcacctaaat cagagataga aagtgctagc
    21541 ttgtttttgt tctccaaggt tatcaagtga taaccttggc caaaatcttt ttctgtaatc
    21601 ttcattttca agatcctttc ttaatgggaa ggaactactg catcgtgaag ttaatcttcc
    21661 attgtatcag ctggagccaa tttgttttcc aatttctcaa cgatttgtgc atgttttttc
    21721 tctgtcaatg taatcttcca agcaaaaata atagcggaga aaatcatcaa agcagcagga
    21781 gcatagaatg cataagcttt gaaagtcgtt acgccatgag cagtgatatc agcagcagta
    21841 gcattaccag tcatcccaga agcgatagcg acaaacccta cgatcccgtt agacaaagca
    21901 ccagcgattt tatctagtaa agggcgaatt gatagagtaa cagcttcgtt acggatacca
    21961 tttttccatt gaccatattc aacagagtct gtgatcgtca tcaaagcgga taagaaaatc
    22021 aattgttgag ggaagtagaa caatactagc ccgatgataa cgattggcaa acttgaacct
    22081 gcgatcgtaa agaaaaagta agaagaaatc atcattgcga tccctccaag gtaaacgtag
    22141 cgacgagaga tgacgcgtgt aagcattggg aatagtggaa cagctactaa accaagtaag
    22201 gcagcaacta gaccaacgat ccaaaattca gttggttggc caagtacata tttgaagaag
    22261 tagaataata cggcagttgt tgctgcattg gcaatcgcat aagcgatata agcaagggca
    22321 agccacatca actgatcatt ttgagcaact gctttgaaca catctttgat cccagctttt
    22381 tcattttgct gacggatcgc agtatcgact tcttttgtgc ccaaggcagt gataatcgca
    22441 gtaccgcctg aaataacagc agcaatcaca ccgaaccaga accagcctga agcgccttca
    22501 atatgtttat gagtaacaag ataggtaaag aaagtaacga tagggacaac gactagagta
    22561 gtaccatttg cacctagaga agagccgaaa cgagcaaacg tagcaaattt ttcacgttcc
    22621 tttgtttccg tactcaaagc tggaatcatt gaccaaaaag cgatatcctt aaatgaataa
    22681 aaactatcca ataagatgaa aacgattgca aataatatga taaataaagt cgtattatga
    22741 gtagctaagc caaagaaatt ggtaaagatt gctaccaaga gtacggaact aacaacgccg
    22801 ccgataacta accatggttt gaatttaccg tattttgtac gagtattatc gatgatgcca
    22861 ccaatcaaag gatcaaaaat aatttcaact aagcggatac ctacaactaa gcttgtaact
    22921 gtagcaatca tttttgcatt cgttgcctta tctgttcctg cgaacatctg gcttgtcacg
    22981 aataccataa aataagtgct taatgtaaca tagaatgtgt cgtgtccaaa agcgcctaaa
    23041 gcgtaggaca cacgttggat cattttgctt ttcataatct gtattcctct cctgttcaat
    23101 atataatact aagtaaaccg gttacaacga ataacaaaga tcttttaatg acttaaactt
    23161 aacaagaaat cgcttccttt ttaatatatt tctgtgactt ttatttaact ttttgttgca
    23221 ttatactaaa ggagtaagga gggatagacg tggagcaatc gattttttta aaaaaggaac
    23281 atcaacaagt agaaaaagaa ttgtattttg atttttgtgg tttctctaaa acgatgccgt
    23341 ttcattcttt tggtcctgct attcgcaatg attacatcct gcatgtcgtg atggaaggca
    23401 aaggatctta tcatgtgaaa aatcaacaat tccaattgaa aaaaggtgat ctgttcttga
    23461 ttcgtccagg agactcgacg ttttacttat cagatggaga agatccgtgg atgtattgct
    23521 ggctttcatt tggtgggagt gctgcagaag aaatcattcg gcagtcgctt ttcagagaag
    23581 accaatacac gatggtctct tctgacatac aaaaatatat cgacattatt ttagaatgca
    23641 tgaaagatac ggaagaaacc ttggaaaatg aattacagtt aacagcatta acctaccgtt
    23701 ttttatcagt ccttttaaaa gatggcggaa aggtcagcgg tggtgtacaa aaggttcatt
    23761 cctctttagc tgttgaaaca gtcaaataca tcgaggcaca ttatgctgaa aaattgtctg
    23821 ttgaggaaat cgcccagcat ttagcggtca atcggagcca tttgtcgcga gtattcaaaa
    23881 atcatatggg taccagtatc aaggaatatt tgatcggggt acggatcaat cgaggggcgt
    23941 ttcttctttc tctgacggat gaatccgtgg aaagtattgc ctatcaagta gggttcaata
    24001 gtctagtcgt atttagccga atgttcaaaa agagtaccgg agaaacggct acgaactatc
    24061 gtaaacgtat gaaaaacgaa aattttaaga atattgcttt ggataccttg aaaaaacagt
    24121 tggaaaaaca aaccgcagtt tcttggacaa cctgattagt ctggttaaaa tgacaagcat
    24181 cggcaaaaga aacttgtggc ggttatgcta cactgtaaag cgaagactaa aaaggaggaa
    24241 aagggatgcg tacacttatc atcattagcc atccaacgat cgaagaatct ttaaatcagc
    24301 aatttttcaa agaagcttct gctggtttac cagctacttg gcatcatttg gaatcaagtt
    24361 atccagacgg aaaaatagat atagagactg aactacagct cttggcccag catgatcgga
    24421 tcattttcca gtttccgttt tactggtata gttctcctgc tcatttaaaa atttggcaag
    24481 ataatgtctt ggaacgagca gcacatgtat taaaagggaa agaactagga atcgtattga
    24541 caacaggtgt ggcggaaaaa gaataccaag ctggaggaaa agaagaatat acgatttccg
    24601 aatttttgag gccgtatcag cgaatcgcaa ataaattcca tatgacctat cttccgccat
    24661 tcgttttagc acaatttatg tatttatccc aggaaaaacg ttgggagaag ctaattgctt
    24721 atcagcagta tctctcattg gaaggcaaac catcgctgac tcagcggatt gactggttta
    24781 ttcaaagagt acaggaaaat cagaaaatgc aggaagaaga atctgaaaaa caagcatata
    24841 tcgtagaagc actgactgag gcaaaagagc agatcgaaga cttgaccttt acactgcaag
    24901 aaatgaaagg aacttcatta tgacaaatga ttggctgatc caacaattag atgaattaag
    24961 cgaaaaatca gaatatcaag accgtgcgct cttatatgaa ataaagaaac tgatggctga
    25021 gatagacgaa cgaacaatgc agctgcaagg agaaatcgac ggacaatctt ggaatcatct
    25081 caactggtga aattttctta taaataacaa agataaaaat gtgcacagcg acaattattt
    25141 gctacaataa gaatatgaag cgtttgataa cgctattata cataaaaatt ggtggtgaaa
    25201 aaaatgtatg atgaaaatga gtggggagaa aatgttcgga tgacccgaag aagacagcaa
    25261 aaacaggcag ctcgtaagcg gatgatcatg attggggcag cagttgccgt gtttttgatc
    25321 atagcaggag gagttgcggg tctatatttt catggaaaaa attcgtcaga agcgaaaagt
    25381 acgaccataa cggaaacaac gacaaagaaa acagagacga aacaaacaag tgagtcatca
    25441 actaaaacaa aagagacaca aacttctgaa gaaaaaacag caaatggttt gccagagcaa
    25501 cttcaagcaa tcgtaaatga ttattcgaaa aagatcgaag aaaagacgcc tgcattgatt
    25561 gaagaatacc agacagaaat tcagggaaat caagagggaa tagctggttt atcagcagtt
    25621 gctaaccaaa aagcacgtga gcttcaagca atctccgacg aagggatcag aaaattacgt
    25681 gcagcgtatc aggcagcaga aaataaagac ggtgtagact tagatacttt gatcaatcaa
    25741 ttatcggcta attatacgaa tcatgtcgct aagatttccg atatttattt gcagactagc
    25801 gcctctcttc aagcagagtc aacaagcaca caagacacaa catcttctga ttctgagaca
    25861 gcagagtcgg tagaagcttc tgaaatgcaa gctcgaacaa cacaagacac aacagattcc
    25921 tctgaaacta ataccaacag cgcgacttca caggctgcga caaccgtagt tttggaagga
    25981 gaaggtccaa atcaaatagc cgaacgaact ggcgtaccag tagaaacgat cttgtcgctg
    26041 aatgggatga gcatggagaa ttatttcctg actcccggtg agacgctaaa attgaattga
    26101 taaaagcaat aaaaaagaac gaagcttcca ctaaggtgaa gcttcgttct ttttttattt
    26161 tccggttctt ttttcgcgta caaagtaatg gatcgtcatg taaagcaaga aaacgagtcc
    26221 aataatcaat gagattctcg tttcaggatt gataaacatg aaaatcaata cgatagctaa
    26281 aaaagcaagt gtcacataat tcgtataagg agatagtggc attttaaaag gatgatcatg
    26341 cattttatct gcgtgcttct ttttgaagcg aatctcgctg atcaaaatca ctacccaagg
    26401 aaccatacca ggcaaaatac ttgagctgta tacgaaaacg aaaatatttt ctgactggtt
    26461 gatgaacatt ggtagaagat aatttaagat cagaccaatt aagattccac ctgagattgc
    26521 tacgacagga taaaaaggcg caccgtgacg agatagtttc agaaattttt tagacatctt
    26581 tccatttatg gcaagtgtat agaccatacg acttgcgctg aaaatccctg aattgcaacc
    26641 tgataatgcc gctgtaatca cgacaaaatt aatcagtcct gcagcaaatg taatgccgac
    26701 tttagaaaaa gtttgtacaa aaggtgaacc aatctcactc aattgattcc acggatagat
    26761 actcacaatg ataaaaatag caccaatata aaaaatcaag attcgaccga tagtggactg
    26821 gacagcttca atgatcgtct ttttaggatt ctctgcttca ccagcagtca ttccgatcag
    26881 ttcgattcct tgataggaag caacaacgat cgataatgca aagaaaaatc ctttgacgcc
    26941 tccagtgaag aatccaccat ttttccaaag atttgaaatc cctactgcct gaccatgatt
    27001 accaaatcca aataagatta ccccaagacc tgcaatgatc atcaaaatga tcgttatgac
    27061 tttgatgatc gaaaaccaaa attctaattc gccaaacgcc ttgacagaaa taagatttgc
    27121 cagcataaga aacaagacga caatgattcc gggaataatt gccggcaaat caggccacca
    27181 ataattcata taagatccta cagcaatcac ttcacttatt cctacgacaa tatattgaaa
    27241 aatattactc caagcggtca agtagccagc cacaggatgg atgtactcgc tcgcgtaatt
    27301 tgcaaaagaa ccagtcgaag gatcaacgta aagcatttcg cctaaagcac gcataatcaa
    27361 atacaaaaag aatcctgcaa tcgcataggc tcccatcact gagggccctg tccaacgtat
    27421 ggttgaggag gcacccataa acagaccgac accgatcgtt ccacctagtg cgatcatttg
    27481 gatatgacgg gcactaagac ttcgagttaa cttttcttct tccatacaaa aactcctttc
    27541 gttgttgagt caacaagaaa aaataatcaa acgtttcaac acatgttttt cattattagg
    27601 ttagccttat tgaactcttg atgtgattct acagaaaatt ttcataaaat gcgaggaaaa
    27661 ttcgaaaaaa actttttcat cattctactt gaaaatgctt tccattttag ttaaactata
    27721 tttaaataaa aagttaggta aacctaaaaa ggagtgtaag atttggaacg tacggccatt
    27781 gtaattcaag acctttcagc cgcttatcaa gggaaaactg ttttgaaaac tatcaacttg
    27841 acgataaatc cacaaaaaat taccggtatt atcggaccaa acggtgcagg aaaatcaaca
    27901 tttatgaaat ctttgctaga gttgatacca gctactactg gtaaagtcac cttttctgga
    27961 cagtcggtaa actcagtccg taaaaaaata gcctacgtgg aacagcgaag tgaattggat
    28021 ctttcctttc caattgatgt attaggcgtt gtacttttag gaacatatcc atctttacga
    28081 attggacaaa gacctgggaa aaaagaaaaa gaacgtgcaa gacaagcttt gaaaaaagta
    28141 gggatggaag aatatgccaa aagacagatc agcgaactat cgggtggaca gcttcagaga
    28201 gtttttattg caagagctct agcccaagga gcagaatgga tctttttaga tgaaccattc
    28261 gtagggattg atgcgttaag tgaacgaaag atctttgaca tcttgcagga attgaagaat
    28321 tcaggaaaaa cgattttgat cgtccatcat gatcttcata aagtagaaga atatttcgat
    28381 gaggttattc ttttaaataa acagctgatc gcttccggtc cagtacaaga agtctttaca
    28441 tcgaagaacc ttcaattggc ctatggtgag atcatcagac atttagtaaa aggaggagag
    28501 aaaaaatgat ccaatccttt attgatggat taatgaatta tcaattcctg caatacgctt
    28561 tggtcacttc catgcttgta ggacttgctt ctggagtcat cggttctttt attattttac
    28621 gagggatgtc tttgatggga gacgctatct ctcacgcagt tcttccaggt gtagccattt
    28681 cttatatgtt tggttttagt tacatctttg gagccactgc ttttgggatg ctaacagcag
    28741 cagtgattgg tttcgtgact cagcggagcc gattgaaaaa tgatacagcg attggaattg
    28801 tctttagctc cttttttgca ttagggatta tcttgatttc atatgcccag agtgcgacag
    28861 atttgtatca tattttattt gggaatgtct tagctgttag ggaaagcgat ttgttgctga
    28921 cagcactcgt tagtggaatc gtcttgatat ttgtcttttt cttttataaa gaattgaaga
    28981 tcacatcatt cgatccgaca atggcaaaag cttatgggct gaacacatcg ctgatccatt
    29041 atcttttgat gttctttttg acattagtgg ctgtagtcag tttacagaca gtaggaacaa
    29101 tcttggtgat tgccatgttg atcacaccag ccgccacggc ttacttgcta acgaaccatt
    29161 tactgaaaat gatcattaca gctgcaggaa tcggtatgct aagtgcagtt gtcggtgtgt
    29221 ttttcagtta tagttacaat tggccatcag gagctacgat cgtgttagca tgtaccgcat
    29281 tttttatcct tgctttttta ttttctccaa caaaaggaat tttatttcag aaaggaagca
    29341 gatagatgaa aacaaaaaaa tcactctttt taatcttggc agttagtttc ttggtattag
    29401 ccggttgcgg aaagcaggct tctgaccaag cggatgaagg aagtaaagaa aagttgtcag
    29461 tcgtggctac caattcgatc ttggcggaca tggcaaaaga ggtcggaaca gatcaaatag
    29521 atatccacag tatcgtacca gtcggaacag atccgcatga atatgaagta ctaccagaag
    29581 acatcaaaaa ggcaagcgat gcagatgtta ttttatacaa cggtttgaat cttgaaacag
    29641 gtaacagctg gttcgataac ttgatggaaa cggctaaaaa agaagaagga aaagattatt
    29701 ttgcagttag caaaaatgta gaacctcttt atttaactag cggtgaagaa catacaaaag
    29761 cagatcccca tgcttggcta gacctatcta acggaataaa atatgtggag gaaatcgcac
    29821 gtatattctc tgaaaaagat gcagaaaatg cgacactcta taaaaaaaat gcagaagcat
    29881 atgtggaaaa actaaaagaa ttagatacac aagcgaagga aagttttgct tctatcgaag
    29941 agaacaaaaa attattagta acaagtgaag gggcattcaa gtatttttca cgagcatatg
    30001 atttgccagc agcttatata tgggagatca atacagaaag tcaaggtacg cctgatcaaa
    30061 tgaaagcgat cattgatcag ataagagcaa aagaagtacc ggttttattc gtggaaacca
    30121 gtgtagactc aagaagcatg gaacgggtag caaaagaaac gggtttgaaa atctatgata
    30181 aactgttcac tgattccata gcaaaagaag gagaacaagg agattcttac tatcagatga
    30241 tgaaatggaa tattgaaacg atccatgaag gtttgtcaca aacaaaagaa agctgaaaag
    30301 tgcaaggtct agcttgagga gcagaccttg cattttttat aagagatatg aaaaaaaatt
    30361 atgctgtttt tcgtcgtaca gatacctttt ttgaagaaat tccgttatag ttagagtaag
    30421 gaaggaaggt gtggctatga attttacacg taaagataaa tatacgatta aagaagaagt
    30481 ctttcgattg atcagccagc aggaaaatac cgacaaggat caagaccttc aatttcttga
    30541 agcagaatta gctaaattat tcatagcaaa tcaaaatgag acaacagaac cagatgaaga
    30601 gctgtacata ggcaaatggt tgtttgatga atttcagcct ttagatgaaa ataccggtat
    30661 cggttatttt gtgttccttt ctccagtcgg cttcacacct ggcgtattag ttaaacaaaa
    30721 cgacgaaata accgtcaaag catggcctgc attattttca gtcatcaaag cagaaggagt
    30781 aatcaaaaag atccagtcgg cctattataa aagtcaattt attgccaaca gcaaattaat
    30841 gaatatgttt tataatcgtc tagtagaaat tgctaggcct gggaaaatcc cgcaaacatt
    30901 cacgtacaca cagcaaaaaa atctctatga agaagtattg tattcccgcg atctgtctga
    30961 gttttcgcca tgggaagagg taaggctcca tgaactgtta agtacaaaac cagtttcatt
    31021 gaattttttt aatgcattag ataacaaaag aaaattaatt tcaacaaatt attgggaagt
    31081 atttgctgca agaaaaaaat ggatggaaga aaagaagatt gccgatcagc agatccagtt
    31141 tgtccagctg aaaaaagaaa aactatatta tgggttatac agccgttaac agcaagcgag
    31201 gaagaccatg acattaaaag aagaaatcat acaagaaagc aaacgattag gaattgacaa
    31261 aatcgggttc accacggcgg aaccttttga ttcattaaaa gaatcgttgg aagaacaaaa
    31321 agcagctggc catacttctg gctttgaaca tccaaatatc gatgagcgtc tttatccaga
    31381 aatgacattt gatcagccga aatcgatcat ttccattgca cttgcgtatc ctactaggat
    31441 ccatgaagaa gtgcctaggg atgaaaaacg cgggcagttt gctcgtgctt cttgggggat
    31501 cgattaccat gatatactca gagaccgttt gaaccgattg atcgaattca tccaaacaag
    31561 agcagaaaaa tggcaaaaag aagaggaatg gcgtctagct ccgcaagtag atactggaga
    31621 actgatcgat gtcgctgtag cacagcgagc tggtttagga tttattggac gaaacggatt
    31681 gttgatcact gaagagttcg gttcatttgt ctatcttggt gagatcgtta ctaatattgt
    31741 atttgagcct gataaaccag gagaatttgg ttgcggtgac tgtatgcgct gcgtgactgc
    31801 ttgtccgaca aaagcattgc ttggtgacgg aagaatgaat gcccagcgat gtttgtctta
    31861 tcaaactcag acaaaaggga tgatgccgga agaatatcgt aaaaaaatgc gaaatgtcat
    31921 ttatggatgt gatatctgcc agttagtctg cccttacaat caaggaaaag attttcattt
    31981 tcatgaagag atggaaccaa aagtagacga aatatatcca aaattaaagc caatgctttc
    32041 gatgtctaat aaagacttca aacagcaatt tgggcattta gctggttcat ggcgtgggaa
    32101 gaaacctttg cagagaaacg cattgattgc tttagctaat ctaggtgatc gaacggcatt
    32161 gcctgagatt tcagaatgtt taacagatgt ccgccctgtc atcagaggaa cagcagcttg
    32221 ggctattgga cgtctaggaa caaaagaacc ggaaaaatgg cttgatgtat tagatgaaat
    32281 attagctaaa gaaacagaag aagtcgttat aaacgaattg gaacatgccc agaaattatt
    32341 gcggagaaag ttaaaataaa aaaatagtta acattattca aagtt
//
LOCUS       DAFLVO010000028        32267 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.028, whole genome shotgun sequence.
ACCESSION   DAFLVO010000028 DAFLVO010000000
VERSION     DAFLVO010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32267
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.028"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(205..585)
                     /gene="yajC"
                     /locus_tag="L1U99_001340"
     CDS             complement(205..585)
                     /gene="yajC"
                     /locus_tag="L1U99_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBN1211890.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(682..1827)
                     /gene="tgt"
                     /locus_tag="L1U99_001341"
     CDS             complement(682..1827)
                     /gene="tgt"
                     /locus_tag="L1U99_001341"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBN1211891.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            2045..2743
                     /locus_tag="L1U99_001342"
     CDS             2045..2743
                     /locus_tag="L1U99_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBN1211892.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(2911..5550)
                     /locus_tag="L1U99_001343"
     CDS             complement(2911..5550)
                     /locus_tag="L1U99_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBN1211893.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(6169..7200)
                     /gene="queA"
                     /locus_tag="L1U99_001344"
     CDS             complement(6169..7200)
                     /gene="queA"
                     /locus_tag="L1U99_001344"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBN1211894.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            7393..8568
                     /locus_tag="L1U99_001345"
     CDS             7393..8568
                     /locus_tag="L1U99_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HBN1211895.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            8572..9213
                     /locus_tag="L1U99_001346"
     CDS             8572..9213
                     /locus_tag="L1U99_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1211896.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            9210..10127
                     /locus_tag="L1U99_001347"
     CDS             9210..10127
                     /locus_tag="L1U99_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1211897.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYSFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            10124..10795
                     /locus_tag="L1U99_001348"
     CDS             10124..10795
                     /locus_tag="L1U99_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1211898.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(11336..11824)
                     /locus_tag="L1U99_001349"
     CDS             complement(11336..11824)
                     /locus_tag="L1U99_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HBN1211899.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(12025..12291)
                     /locus_tag="L1U99_001350"
     CDS             complement(12025..12291)
                     /locus_tag="L1U99_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBN1211900.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(12291..12554)
                     /locus_tag="L1U99_001351"
     CDS             complement(12291..12554)
                     /locus_tag="L1U99_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBN1211901.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            13030..13215
                     /locus_tag="L1U99_001352"
     CDS             13030..13215
                     /locus_tag="L1U99_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBN1211902.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(13357..15180)
                     /locus_tag="L1U99_001353"
     CDS             complement(13357..15180)
                     /locus_tag="L1U99_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HBN1211903.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(15778..18483)
                     /locus_tag="L1U99_001354"
     CDS             complement(15778..18483)
                     /locus_tag="L1U99_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBN1211904.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(18789..19736)
                     /locus_tag="L1U99_001355"
     CDS             complement(18789..19736)
                     /locus_tag="L1U99_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HBN1211905.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            19926..20195
                     /gene="rpsN"
                     /locus_tag="L1U99_001356"
     CDS             19926..20195
                     /gene="rpsN"
                     /locus_tag="L1U99_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBN1211906.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(20371..20733)
                     /locus_tag="L1U99_001357"
     CDS             complement(20371..20733)
                     /locus_tag="L1U99_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBN1211907.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(20744..21865)
                     /locus_tag="L1U99_001358"
     CDS             complement(20744..21865)
                     /locus_tag="L1U99_001358"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBN1211908.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(21881..22231)
                     /locus_tag="L1U99_001359"
     CDS             complement(21881..22231)
                     /locus_tag="L1U99_001359"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBN1211909.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(22361..23872)
                     /locus_tag="L1U99_001360"
     CDS             complement(22361..23872)
                     /locus_tag="L1U99_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBN1211910.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(24194..25546)
                     /locus_tag="L1U99_001361"
     CDS             complement(24194..25546)
                     /locus_tag="L1U99_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBN1211911.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(25699..26775)
                     /locus_tag="L1U99_001362"
     CDS             complement(25699..26775)
                     /locus_tag="L1U99_001362"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBN1211912.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            26971..28716
                     /locus_tag="L1U99_001363"
     CDS             26971..28716
                     /locus_tag="L1U99_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBN1211913.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(28996..29433)
                     /locus_tag="L1U99_001364"
     CDS             complement(28996..29433)
                     /locus_tag="L1U99_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HBN1211914.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(29417..30790)
                     /locus_tag="L1U99_001365"
     CDS             complement(29417..30790)
                     /locus_tag="L1U99_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211915.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(31112..31600)
                     /locus_tag="L1U99_001366"
     CDS             complement(31112..31600)
                     /locus_tag="L1U99_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1211916.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(31622..32224)
                     /locus_tag="L1U99_001367"
     CDS             complement(31622..32224)
                     /locus_tag="L1U99_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBN1211917.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         9232 a         6887 c         5950 g        10198 t
ORIGIN      
        1 acagttattt ttaaatataa aattgcttta tttacaggtg tttgtataga aaaatatata
       61 aagttattta ttattattta tatgacacac ccgattattc aatattgagc aatatatccc
      121 atgctcttat ctctttcttt tttgaataaa aaatgaggta ggacatcttt ctgccctacc
      181 tcgtctttaa ataagctttg atacttattt ttcttccttc tcttctgtct cttccagcgt
      241 ttctgttgtt tcagttttta cttcaactgt ctcagctggt tcttctgttg tttcaacagt
      301 agtcgttgca tcatttgtta cgacagtccc tggtttgacc gttttgattg ctgcacgatc
      361 gtactcaagg aagatccctt cgcagtctaa aacaactgtc cgtttgtcat tgtcgatttc
      421 tgaaacaact ccatgtaatc cgccgatcgt tacgactgaa tcacctggtt tcatgctatc
      481 taacaagttt tgacgttctt gctgttgttt cttttgcgaa cgtgacataa aaaaccacat
      541 tgctaatagc gcgataaaca tcacaagcat tggtaatgtt cccatttttt tcacctcact
      601 aattctgtat ctacaaaaaa cactttagca gaaaaatgct gataacacta gttttttact
      661 taatttttaa aagattttcc tttagaagct ttttgcgttt tctttattga acccgtattc
      721 ttcaaaaaag gcttctctaa attcaagcaa attatcatcc atgattgctt gacgtacttg
      781 tttcattaga ttcaacaaga agtataaatt gtggtaagaa gtcaaacgaa tcccaaatgt
      841 ttcatcacat ttgatcaaat ggcggatata ggcacgtgta tagtttttac atgtataaca
      901 atcacatttc tcatcaattg gacggaaatc atgggcatat ttcgcatttt tcactactag
      961 acggccttga gaagtcatac atgtgccatt tcgagcgatt cgagtaggca agacacagtc
     1021 aaacatgtct actccacgga taacaccatc gatcaatgaa tcagcagcac cgacacccat
     1081 caagtaacgt ggtttgtttt cggggatcaa cggtgtagtg aattctaata cacgattcat
     1141 ttctgattta ggttccccga cagataaccc gccgattgag taaccaggga aatccatccc
     1201 gactagatct ttcgcgcttt gacgacgaag atcttcaaac cctgctcctt ggatgattcc
     1261 aaataatcct tgacggtctg gattagcatg agctttcaat cctcgttctg cccatcgaga
     1321 cgtacgttct actgattttt tcacgtagtc gtaactttca tcgaatggtg gacattcgtc
     1381 aaaactcatc atgatatcag agcccaattt attttggatg ttgattgctt tttctggtga
     1441 taaaaacata cgcgaaccgt tcaagtgatt tttgaaatgc acgccttctt cttcgatatt
     1501 ccgcatatca cttaatgaaa aaacttgaaa gccgcctgaa tctgttaaaa tcggttgatc
     1561 ccagttcata aatttatgca gtccgccagc ttcttctact aagtcttcac cagggcgtag
     1621 ccataaatga tatgtattac ttaaaataac gccagcaccc atttctttca actcttctgg
     1681 ggacattgtt tttactgtag ctaatgttcc tactggcatg aacattggtg tggggaaagt
     1741 tccgtgtggc gtgatcaatt cccctaaacg cgcgccagta tgtttttctt tcttgattaa
     1801 acgatagcga atggcaggtt gcgtcattca tttccctact ttctatataa aatatcttga
     1861 caactcccac catcataatc gtttcaagtg ctttttgcaa gttccctcgg cttccttcta
     1921 ctttatttaa tattcttttt tttatccttt ttttatgaat aacaaaaaaa agaaaaacat
     1981 tatgacagaa atattttttg atacatggta tattggtgtt attaaagaaa aggagggaaa
     2041 aatcatgcaa tcttctgcag aattaaaacg ccaagcaaaa gagagtctaa aaggacgttg
     2101 gggacaagct gttttactaa atctaatccc tacattgatt ggtattgcta ctattcttct
     2161 tattatgatt cctattatct tgtttgccac caccatatat gatggatcag cgagcgtctc
     2221 agaagcgaca acttcaggag gcggtagttc aggaggcggt ggcggaatta tttccagcat
     2281 cattagcgct ttgttcatga gcggtatttc ttggacttat cttgatattt tacgtggaca
     2341 aaaagatcag atcgaaccat tcaaagatgc atttcgtgga ttcaaaggtt tgtttatcgg
     2401 cggagtgatc agcttagctg tgctgatctc gatctttaca acattatggg gtttgctatt
     2461 agttattcct ggaatcatta aaagctattc ttattctcaa agctatttta tttactacga
     2521 tatcgtccaa gaaacaggac aaacacctaa agtactggat acgatcactg caagtcgaaa
     2581 attgatggat ggttataaag gacaactttt ctggttagat ctttcattta tcggctggca
     2641 tatcttagca ttagcaactg ctggtattgg ttatctatgg ctcagcccat acatttctgc
     2701 aacaaaagca gcattttatg aacaattgcc aaaagatatt taaaagagag tgtgacttgt
     2761 gaccgagggg gtggcaggag aacaccgttt atcgagaggc agtaaaagaa acattcagcc
     2821 cattagcaaa aaggaggtgt gacaacattc atgtcacacc tcctttttgt atagttccag
     2881 taaaaagaaa atcaacttag aaacagttaa tcattcctct tcttctgctt ccggtaatcg
     2941 atggaacttg atcagttcat tcaccgcgat tggtacgata gataaaatcc ctaccaagaa
     3001 ccagtgattc aaactgatgt gtactaggcc gaatagttct tgcgtaaatg gcagcaaagc
     3061 aacagccgtt gtaatagcta atgccagtaa cgccatttct accaaagctt tattggtcgc
     3121 taaattgact ttgaagatcg attggctgct gcgtacattg aacacatgca gaatcgatga
     3181 ataagctaag atcaagaatg caacagtttg accgacatgc tgacttgcgt ctacccatgg
     3241 gctgatagta tcgacataac tacctaaata ataaccaaac aaggttacga tggtgaagac
     3301 ccctgcattt atggcaattt tttgcaataa acctcgagca aagatccctt catttttcgg
     3361 aatgggtggc tgatccatga tgccgtgttc cgctggctct cttcctaaag caaatcctgg
     3421 aagtccatca gcaactacat tgacaaacag tagttgcaca gctgtaaatg gtgctcccca
     3481 tcctaacagc atcgcaatca aaacaataaa gatctccgaa atattacagc ttagcaaaaa
     3541 gttgatagct ttacgaatat tctgataaac cgaacgtcct tgactgacag cgtctacgat
     3601 cgtcgcaaag ttgtcatccg tcaaaatcat atctgcggca ctttgcgcca catctgttcc
     3661 tgtgatcccc atggcacacc caacgttact tgctttcaac gctggtgcat cattcacacc
     3721 atccccagtc atcgctacga ctgcacccgt acgttgccaa gatttgacga tccggatctt
     3781 gtcttctggc gttacccgag catagacaga gagagctttg acacgcgcat ctaattcttc
     3841 gtctgataat tgatgcagtt ctgatcctga aagtgcttct gacggatcat tcaagatacc
     3901 taattctttc gctatggcac tggcagtcac cacatgatct ccagtgatca tgactgtttt
     3961 gatgccagcc tttttcgctc gcttgattgc tcctttactt tctggacgtg gtggatcgat
     4021 cattccgatc agaccaatca aacgtaagtc tttttccagt gcttcagaag aaatatcttg
     4081 cggttcttcg tcataagtag cataaccaac agcaatcact ctcagtgccc gtttaccaaa
     4141 gcgatcatta acgatcgccg cttgttctac atcgcctgaa ctaaagcgcg gagcaagaac
     4201 atcgaatgct cctttggtga ttgagatgta tttttcgccc atttggtgaa ctgttgtcat
     4261 catttttcgt tcagaatcaa aaggaagctc gtttactcgt ggatattttt cttctaattc
     4321 tgcctttgta tgataattct cttcaacagc ccttacgatg gctacttctg ttggattacc
     4381 tttgataaca aggtcgtcat cttcttgctc gaccgtcaca tctgtacata gtgcagccat
     4441 tttcaatatt tccatcgcgc tgttcgtcat tgaatcttcg atattcgtta cttcatcttc
     4501 tttgctccat acccggcgga cgcgcatttc attttgtgtc agcgttcctg ttttgtctga
     4561 gcagataaca ttagcggttc ctagcgtttc aactgctggc aactgtcgga tgatcgcatg
     4621 tttcctcgcc atcttctgca caccgtatgc aagtgtcaac gtaacaataa cagtcaaggt
     4681 ttccggtaca gctgcaacag ccaaggaaat cgaagtcatg aacatctcaa ggagtggttc
     4741 tccttgcagt tcaccaatca caaatactaa agccgcagcc gctaaagcga tcatactgat
     4801 tcgtttgcct agctgattca atcggacctg taaaggtgtt ttttgcatag tattttcgtt
     4861 caaaagatcc gcgatcttac ccatttctgt agccatgcca atggcagtga cgatcgcttt
     4921 cccacgacct gcagcaaccg tacatccttt aaataccata ttaagttggt cacctaatga
     4981 ctcatcttct tcagcaataa atgctgcatc tttttcaact gcttcacttt ctccagtcaa
     5041 cgccgattct tctacacgta attgtgatgc ttcgatcaaa cgggcatcgg cagaaatagc
     5101 atcaccggac tctaaaacaa gaatatcacc cactaccagt tgctctgact caacagtggt
     5161 cactttgccg tctcgtatga cagttgccgt ttgtttattc atatcttgca aggattccag
     5221 tgctttttct gcgtttcctt cttggacaat cgccaatacc gagttgatca caacgatagc
     5281 gatgatcagc agtccttcaa ataaatcccc atgttctgta gcaaatgcgg tataaaagga
     5341 aatcaccgct gctacaagaa ggatgatcgt tgtaaaatcg gacaagcttc gaaagaattt
     5401 tttgatcatc gattctttcg gcgcctcatc gaatttattc aatccctgct tttttcgccg
     5461 ttcatccact tcttgtgaag acaacccagt atctggatct gcttctgtta ccttctttac
     5521 ttcttctatt gtctgcttgt attcttccat cctattcctc ctttaaaatc ttcgtacaaa
     5581 aaaaggtact tattttacta taacatcctt tttttattta cttcaaataa agggcttatc
     5641 gattatttgt taagaaagcg taaaatttaa agtgcttata tttgcaaacg ctaccaaagg
     5701 atgctattat atagatgtaa ggaaggagga taccatcaaa tagacagaag aatttctcga
     5761 tagaacagtg taagcaaaca aagttgttag aagtacaggt ttcacccaga catgcgtgta
     5821 gagtacaaac ctataaatag tgaatgcgta tggatgtttg gatcacgaag tatccgaaac
     5881 aagaagtaat gcgatacgta acaattgaat aacgtaaacg tctgaaaatt gaataggaac
     5941 aagagatgtt tcaaatgttg aagatgtaac gaaaacaaaa tttttgttta acatgaagaa
     6001 attcaacacc gtgctttgca tgtatgatgg aaagttacaa tcatttctgt ttatttgaat
     6061 ccttccgagg tacaagaaag ccgagcttat cgagagctcg gctttttctt tgtcataaaa
     6121 tctttgtaaa gcttttttgt tattcaaaac tagcggcttt tcataacctt atttcacgaa
     6181 catcgcatct ccaaaactaa agaaacgata gcgctcttca atcgcatgct ggtaagcaga
     6241 taaagtcaat tctcttcctg caaaggcact aactaacatg actaaagtcg attttggcaa
     6301 atggaaatta gttgagaaag cttctaccac tttgaattca tagccaggcg taatgaaaat
     6361 atcagtccat ccgctgtctg ctttgatttc tccattaaat ttcgttccaa tcgtttctaa
     6421 tgttcgaatt gaagttgttc cgacagccac gattttcccg ccatttttac gtacttggtt
     6481 caatcgctca gccgcttctt ccgtcaaacg gtagaattca ctatgcatat ggtgttcttc
     6541 aattttatct acgctgacag gtcggaatgt acctaaccct acatgtagtg tcagatagac
     6601 taattcaaca ccctttgctt cgatctcatc aagtaattct ttcgtaaaat gcaatccagc
     6661 tgttggcgct gcagcagaac cattttcttt cgcatagaca gtttgatagc gatctgggtc
     6721 ttccagacgt tctttgatat atggaggcaa tggcatttct cccaatgatt caagaatctc
     6781 tagaaaaatt ccttcatact caaagtcaat gatccgtccg ccgtgttcca attcttcttt
     6841 cactactgct tgcaatctgc catcaccaaa agagattctt gtcccaactt tggcacgttt
     6901 cgcaggtttg atcaatgtct cccacgtatc tccttgtgta ttcgttagaa gaaggacttc
     6961 taaatgcgca ccagtatctg gtttttctcc atataaacga gcaggcagaa ctcgtgtatt
     7021 attcataact agcgcatcac caggctgtaa ctcttcaatg atttcatgga aatgtttatc
     7081 ttccatctct ccagttttcc gatccaaaac aagtaaacga gaatgatcgc ggtcttttaa
     7141 tggtgtttgt gcgattaatt cttccggcaa gtcaaaatca aaatcttctg ttgttaacat
     7201 atcgtcactc actttctatc atgtgcttca tcattctatc atgtttttcg ttctgttggc
     7261 aaaatcagca ctttttcact tctatttttt gttttcctaa ataaaaaaac taccctattt
     7321 gtattttttc attgttttag gcatactagt aatagatagt tcttcattga aaatagaaaa
     7381 agaggtggca ccatgattga atttcaaaat gtgtcaaaaa tttataaagg tggaaaagtc
     7441 gctgtagagg acgtcaatct ttcatttgaa aagggtgagt tcatttgttt tatcggtacg
     7501 agcggaagcg gaaaaacgac gacgatgcgg atgatcaacc gaatgactga tccaacacaa
     7561 gggaaaattt tgattgatgg aaaatccatc caagaaattg atccagtgga attgcgacgt
     7621 cagatcggct atgttatcca aagtattgga ttgatgcctc acatgacgat ccgtgaaaat
     7681 atcactcttg tccaaaaatt gttgaaagtc agtcaagaag aacggaataa aacagctgaa
     7741 aaaatgattg atcttgtgga attgccccgt gagatgttag atcgctaccc acatgaatta
     7801 tctggtggtc agcagcagcg tattggagtc gttcgtgccc ttgcagcgaa tcaagatatc
     7861 atcttgatgg acgagccatt cggtgcgctt gatccaatca ctcgtgattc cttgcaagac
     7921 cttgtcaaag atttacaaga gcgtttggga aaaacgatcg tatttgtaac ccatgacatg
     7981 gatgaagcga ttaaactagc aagccgtatc gccatcatga gtgaaggccg tgtgatccaa
     8041 tttgatacac cagaaaatat tttacgtcat cctgcaaacg atttcgtaga agagttgatt
     8101 ggagaagatc gcctactaca agccaagcca aatgcgacaa gagtcggcga agttatgcta
     8161 aatacagcaa tcacgattac accggaaaaa tcattacaag aagcaatcaa actgatgagg
     8221 gaaaaacgtg tagatacgtt gttagttacc gataattcga atgtattaaa aggatttatc
     8281 gatgtagaaa cgttgaataa aaaacgagga aaagtatcca gtgtcggcga cattttgaat
     8341 aaacatgttt tttacgtaaa agaatccgcc tatcttcgtg ataccttgca acgcatttta
     8401 aaacgcgggc tgaaatacgt gccggtcgtt gatgaacaga acaaagtcgt aggtatcctg
     8461 actcgtgcat cattagtgga tatcgtctac gatgtgattt ggggagaaga tcccgcaact
     8521 actgatgttg cagagtcagc tactcctgaa gaatctaagg aggtctgacc tatgcagcag
     8581 ttttttcatc agcacggttc agaaattctc tcaaaaggtt ttgaacatct ttatatttca
     8641 ggacttgctt tgatcattgg tatcatcatt gctgtaccgc ttggtgtctt actgacacgt
     8701 tttccaaaag ctgccacgat tgtgattggc ttaaccagtg ccttgcagac aatcccttct
     8761 cttgctttat tggcattgat gatcccgcta tttggcgtag gtaaattacc tgcgattatc
     8821 gcactcttta tttattcatt attgccgatt ttacgtaata cgtacattgg gatgaaaaat
     8881 gtcgattgga attatcggga tgtggcaaaa ggcatgggga tgactgagtt ccaatccatt
     8941 ttttccgttg aattgcccat tgctatgcca acgatcatgg ctggtattcg tttagctgcc
     9001 gtttacgtga ttgcatgggc tacacttgcc tcttatatcg gcgctggtgg tttaggcgat
     9061 ttgattttta gtggactgaa taattaccaa ccagatctca ttttggcagg tacgatccct
     9121 gtaacaattt tagcactatt ggctgattgg cttctaggtc tcttggaaca ccggctgaca
     9181 ccgatcgcac ttagagagga gaatgaagaa tgaaacgtat actaaaaatg accatggttc
     9241 ttttctctct tcttatactt gcgagttgtt ccttccctgg tcttgccagc aatacagatg
     9301 aagacaccat ttcgatcaca ggtggaatca cttcagaagc acagatctta gcaagtctag
     9361 ttgccggaat ggttgaacat tatacagata aaaataccgc aatcatcaac aatctggcta
     9421 ctacaactat caaccatcaa gcgatgatga acggagatgc ttcaatttca gcggctcgct
     9481 acacaggaac agatttaacg actacattga accttcctcc tgaaaaagat ccgaaaaaag
     9541 cgtttgctac cgtgaaagat gaatttgaga aaagatacgg tcaaacgtgg ttcccgtcct
     9601 atagttttga aaatacgtat gtctttcttg ttcgaaaaga caccgcacaa aaataccatc
     9661 tatctaaagt cagcgatctg aaaaatgtag cggatgaatt agtagctggt gtagatactt
     9721 cttggatcaa tcgtaaagga gacggttatg acggcttcca agaaacttat ggcttctcct
     9781 tcaattcgat attacctatg cagattggac ttgtttatga cgcagtcgaa gcaggaaaaa
     9841 tggatattgt tcttggctac tctacggatg gacggatcgc cagttatgat ctagtcatgt
     9901 tggaagatga tcgtcaattc ttcccaccat atgatgctgc tccagttgta gacaacaaga
     9961 tattagctga tacgcctcat ttaaaagaag ccttaaataa gttaggtcat accatcagta
    10021 cggaaaaaat gcaggaattg aactacgaag cagataataa tctagtggaa ccatcagtag
    10081 tagcacaacg tttcttacaa gaaaaccact attttgaagg gaagtgaagc aattggataa
    10141 aatgaatgtc tttcaacaat ttttctatta tttccaggaa aatggctcct atatctttgc
    10201 acaatttatc cgtcacttcc tgatttctat ctatggtgtc ctctttgcag cagttgtcgg
    10261 gattccggtt gggatcatga tttctaggag acgtaaatta gcaaactggg tgattcgttt
    10321 ggcgaatatc atccagacga tcccttctct agccatgatc tccattttaa tcattggatt
    10381 aggcctggga gtcaatgtcg tgattgttac tgtatttttg tattccctct taccgatcat
    10441 caagaatacg tataccggga tgatccaagt agacaaaaac atccttgatg tcggcaaagg
    10501 catggggatg actgctagac aacgactatt catggtagag ttaccactct ctgtttctgt
    10561 tatcatggca ggcataagaa acgcgttagt tgttgccatc gggataaccg cgatcggtgc
    10621 attcgtcggt gctggtggtc ttggagatat cattatccga ggaaccaatg caacagaggg
    10681 cacatcgatt attttagcag gtgcattgcc aactgcatta atggcgatca tcacggactg
    10741 gcttttaggt attttggaaa gacggctaga tccagccagc cgtacatcac gctgatgtta
    10801 ttgtaaaaaa caaaagcttc tgcgaccatt tgttggtcgc aaaggctttt ttagttctgt
    10861 catttttaag gcaataatcc actctgattc ttccctcctt atgggcaaag agttgctttt
    10921 cttagctatt tatccattcc gtatactcca acttcatact gccaacgggt tcatatctgc
    10981 atccaccgac taagtttttt tcttatccgc taaggcattt tgccaatcca ttttcccatc
    11041 actcgtcatg gaattcatac cacatgatct ctaaatactc gtctgcttgt tctttgaatt
    11101 gggcatcaat tcttacatcc tttggcgtgg ctttcattta agccttttcc atcagtcctc
    11161 gattgttcga tgccttcagc tgcatcatca aaactggtga ctgccgtatc ggtaacttcg
    11221 atcatctttt atacaatcgg gaacttgcca tcctcatcct tggctaaaaa catatctagc
    11281 cattccagct tctcgccatg ggaggtttgc ggttcctaaa accggtacac gattcttatg
    11341 gactgcatcc gtcgcaacta gacttggcga tacgatgatc cttcaccaga agagcacccc
    11401 cgtaaaccaa ttgatcgata tattgccaat aagaaaagac attggcgtaa aagatatcga
    11461 tccctcgtga tgcattgccg ttgatactgc tattcatggc cgaaagcgcc acgactttaa
    11521 cttcttccgt ttgagtgaca ttcatgttcg gcaatgtcgc tttggatacc cgctctgcta
    11581 aaggaacgac actggtattg tatttcgtat ctgtatcttt tccaaaagac catgccaacg
    11641 aatcctctgg gaaccaataa gacgactccg gttgattgtc cattgctttt ttcaacatac
    11701 ttttggctgt ttctcgataa acgacatttc caattgtctt cgcctcactt tggcgataat
    11761 cgatggtcgt tgccactgcc aacactaaca acgatgctcc aattttactg attttccttg
    11821 tcacacttct tcctccttgt tttacataaa cccgtcaaca ttccattcct aaactcaaac
    11881 aatgaccctt caaaggtgga gatataggaa caaattaaag aaatcatgca ataaatccaa
    11941 gaaggttggt tttagaacaa aaaaagagtc tcctttttgg ggagactctt tgttaactat
    12001 ctaaaaaggt tggctcttct cacttcactc ataatgtgtc caggcagaat aaatttctac
    12061 aactttattt tcctcatcaa ctttgtaaac cactcgatgc tgtctattca gcctgcgtga
    12121 gtatctgcct tcatgtgtag gtctcagctt ttcaaaagac tgcgtgggca tatatggatc
    12181 ttccttcaat gtctgaatca cttcttcaaa ttgtttcttt aaattcgttt gcttgatttt
    12241 tcttaaatcc actttcgcag agtttttgat tgcgactgta tagttactca tcaaagagct
    12301 tcccaatcaa tatcatcgat attcgtaaag ctactgtcgt ctttttcgcg gtctcgtact
    12361 ttatctaaag tacctgtttg ctcaagaaaa agggtttctt gaatcgctct ccagtcttcc
    12421 agcccaatca atacagcatt gtttccacta cgatcactaa taatctcgat ttcagtatga
    12481 ttttcattta cctctttcaa taactgataa aaatttttac gagcagtgct aggattcatc
    12541 gttgtattag ccattgtctc tcctcctttt tctgatataa ttatagcgta cttgattaag
    12601 tacgtcaaaa aaatacaata aagcacttaa attcagcaaa cttttcctct tttttacata
    12661 gagaaaaaga ccccttttta gggaggatct ttgtccacgc tcacttctta ctcctttacg
    12721 actagcggta gccaaacgta aagtaattgg taacaacgta tcatctttag caaaggtcga
    12781 atccaaagcc tgtgagtcta tgcaacaaca ccaatacacg aaggttcctc gttgcagtgt
    12841 gacttgattg atatcttgaa taacctgagg atacgcacga aagatttgta acggttattc
    12901 aaaactgatt ttggccgtca agtcttctac tgcctcaaaa atgattgcct ctttcgtctc
    12961 ctgtcattca tgttcactat cgatttgata cttgcttaga ccgttgggtt tgtgaatcac
    13021 caattaaaaa tggcactgag ttatggtaac aaaaaatggt cacttgacga ggctgagatt
    13081 cctacttatg aagacacatg gcacttaaga gtcgaggtaa aggaagaagc tgaaaatata
    13141 ggaggctgta cattatttgg caaaggattc ggaaattatg atcaagacat caaaatcaaa
    13201 atgttttaca gctaaatagg aagaataata acatttcata cgctgttccc atctttaatg
    13261 gcttatagag ggcaccttta gctgagaata agacaaaaca gaccctctag cttcaattaa
    13321 gagctagagg gtctgttttt gattttaaaa cttggtttat ttcttcaaat ggtagctata
    13381 ggtgctgaca acgatatttt cacgccaaga caatcgcaat cttaaccgca aacttgtttg
    13441 gttatggaga atattctgcc agcgtctgtt tggtacaaat tgaggaatca acacagtagt
    13501 tgtatagttt tgtttcgctg catttttact tacgatatct acataacgga taattggatt
    13561 ttcaatcgag cgataagaag agtggacgat tgaaaaacgg acatctggga aatgcttttt
    13621 aaattctgct tcgatttctt tttctttttc gacatcttcg tctagcgaaa catgcatcgc
    13681 aacgacataa tcaccgatcg aacgtgcgta attcaacgca ccgatattta cccgtgtcac
    13741 attcccgact aatacaagaa cggtattccc gtcataatca tgtagttttg catcattttc
    13801 taaacgaagc tgttctgcta cttttttata atgatcatgg atcttataaa aaatgaacat
    13861 aacgattggc ataatgatga agaaaggcca aatgtcccct aaccgataga caaacaaaat
    13921 cgcaatgatt gcatatgaga tgaacgcacc cgtaatattg gcaatcgatt tgcttaacca
    13981 tctttttcct tcttttttcc atttgacgac catccctgtt tgagataaag caaatggaat
    14041 gaacacgccg atagagtata acggaatcaa gcgttctgtt gagccatgga aaataaacag
    14101 caatacgatc gaacctagcg ctagtgtgat aatcccattg gaatagccta gtcgatcccc
    14161 acgatcttga tacatgtgag gcatgaattt atcttttgcc agattgtatg caagaactgg
    14221 aaaagcagaa aaaccggtgt tagcagcaac tgctaaaatc agcgctgtag caaattgaag
    14281 gacgtaatac aaaataccat gtccaaagac agctttacca atttgagaca aaacagtgac
    14341 ttctttttca ggaacgatcc cataccaata gttgataaat gtgatcccca cgaagaagaa
    14401 acctaagatc aatgccatca tcgtcaatgt agcagcggca ttttttgctc ttggcttctt
    14461 aaagaatggt acagcattac taatcgcctc caccccagtt aaagaggaag aaccagaaga
    14521 aaatgctcgt aaaatcaaag cgatagaaac acccggcaca gccgctcctg gaagtgcagt
    14581 agcttgcaat ggcacagcac ctgtcacgat attatataaa ccaacaacga tcagtaacga
    14641 gatcacaagg ataaatgtgt acaccggaaa taataggaac gatgcagatt ccctcagccc
    14701 acgaagattc agcatcatca gtagcaaaac gattgtcaca gaaatagcga cttgatgacc
    14761 gtagagtgct ggcaccgctg atgtgatcgc ttcagcacct gctgagacag atactgctac
    14821 tgtcaacatg tagtcgatca ataaagagcc accggaaatc aagccagcat tctttccaag
    14881 attctcactg ctgacgacat atgctccccc gccatgagga taagcatgga tgatttgacg
    14941 atatgatagc gttaatgaaa tcaataaaat aataacaaaa gcggcaatgg gtagcgaata
    15001 ccagatggct gcagcagaca aagcgactaa aacgacaacg atttgttccg taccatatgc
    15061 aatagatgat aacgcatcag acgacaataa tgccaaagca gcaaatcggg ttaatttgtg
    15121 ctcatcattt tcagcagatt ttaaaggctt acctactaac aaccttttta agtaatccaa
    15181 tttctaaact cctttacaca caattttact tcaagtttta tagtcgaaaa tttatagtaa
    15241 acaagatgtt atagtacgct cactgacctt aaaagtcaat aaactttaag aaaataattg
    15301 gaaaaaaaca gaaaaatatc aagcgctttt tcaaacgctt taatacagca aaaatctaac
    15361 atttttttat gggctttttc tttgaattct ataataaaag gatagaactt gacttagaaa
    15421 atcaagttct atcctttttg atatcttaac ttttggaaga gagatgtaag gctgctttct
    15481 acccatcatt cttactactc gaagcatagc gcagttgtca caacctcttg ataaacggtg
    15541 tttaaaagct tgcatctgcg gtaataagcc caaccaaatt aaaaacataa gaagctgttt
    15601 ttatttggtc gttcttatta cttgatgcag agcagctttt ttacaacctc ttggtacacg
    15661 gtgttcaatc agctgaccct cggtattagc tcaaaaaaac ggcaaaatat gaggaactat
    15721 ttttccattt ttttctctaa tactcaggtc aaaacactga tttcacaacc tcttttttta
    15781 atgaaaaata tggctctcat gcgccgcttc tttgaatttc gtcatttttt cttcgatgaa
    15841 cggatagatt gccgttccta cgattccaaa gacaacaaac aaaccgatca tgatccagat
    15901 tgctttcgta gcatttggcc aataaattcc tcctgcagat tcccgtaaca agtttaccgc
    15961 atgagtaaat ggcaagaacg gattgatcat ttggaagaat ttccctgaga cttggatcgg
    16021 atagttcccg cctccgccag agatcgacag tactaagatg ataatagcga tccctttacc
    16081 gacattatcg aataatgcag ccaagacata gacgatcatc atgaacgcta aggcgatcaa
    16141 gacagcaaat gacacgctgt agaccggatt ttggacatct actcctagta agaaaatatt
    16201 ccctaatgta acgatcaagc tttgcgcaat cgccattgtc aaaaatgtca gcatacgagc
    16261 aacgaattgt tctcgtttcg taaaattgtt tcggtctttc tttcctaaat agtattctgt
    16321 cgtagcaaca cttgaaagaa gaacagcgcc gacccacaga catagtgcag tataaaacgg
    16381 ggtgctagct gaaccgttat ttgcgattgg ataaagcgca ttggtttgta gctcaacagg
    16441 ttgtgtaaag aagtcacttt cttttgttgc gtctagtttc aataatttga tgacttcgcc
    16501 tagatcgact tcttgttcgc cttttcggat cgcgtctgct gctttttgga taccagcttt
    16561 gatatttggc cagtcattgt tgatcaagtc cgcagcagcg ttcacagctg tttcgacttc
    16621 tggcattttt tcatttactg ttgtcaatgt accggtgatt tcatttttta gtgctggcca
    16681 atcattttgg ataaaatcag cggccaatcc taatttttgc tgaatgatcg gtaattcatt
    16741 gttgtatagg tctgcccctt cattgatgcc attgacgatg gtatccatat ttccattcag
    16801 cattgtattg gcatcatgga tttcttgtcc aattgcaggc atttcttttt gatatttttc
    16861 taaaattgcc actgcattcg ttacagttgc tttcgttgag ctgagaagcg aatcaaagtc
    16921 gatctggtcc gctttgctca gtgcgccttg tgcagtccca atcgtatcga tgacttggtc
    16981 tagtagagaa gtgacagtgg aactgatttg acctgtattg ataccagcaa tgatgccatt
    17041 gatattatta acaacggcat caatttgatc tagcaattca tcaatagcct tcgtgtcttc
    17101 attttgaaca gctgtgttca aagcagatag gcggttttgc agattgctta gcaagggttt
    17161 taattgattt agctgatcaa taattggctg taatttcgta tttccagcac ttgtttgcaa
    17221 tttagtcagg aactcgacca gtttatcgat tgcattttgt tgttgagata ttccgtcaat
    17281 aaagccgttc aatacattgc tgatgttttt cttttcatca tcagtcagct taccatcttc
    17341 aatagctgtt cttacagtat ctattaacga acctgtcgtt gttgccactt gtccaattga
    17401 cttcaatgta acatctacac tgtttgtgat gcttggtatc gcatctttca gctgagaggc
    17461 acctgatttt gtttggtttg ctagatcact tgcctgattt tctaaatttt tcacatctgg
    17521 caagatatct tgtacttgtt ggatgatcgt caagccttgt tttgcttcat cgattccttg
    17581 gttcattgtc tcttggatcg aagcaaaatc gccgtcgatc tctgctagtt gcttaccggc
    17641 attttggatc tctgggattt tttcttgcaa atcaaggatg atttttgctt gatctttcaa
    17701 ctcaggcatt ttgtcattca atgcaacgac tttttcaccc atctcatcta ctttagggat
    17761 gtaatccacg aattcatttg ctttattcag tttttccttg atttcaggta gttgactttg
    17821 taattcgagg acttgttttg tgtagccgtc gatcgtgtcc aaattttcat ctgttgataa
    17881 aatcatatct ttaactttat tgatacttac taggttcgta tcgatgtcgt aacctatctc
    17941 attgaatact ttcaataaag tcgaactggc tgttttgata aattcatttg tgatttgcga
    18001 ttggatcgaa cttgctcctt tatcggtgat tttcggtgca atcgcattga ttttttcatt
    18061 taccgtatat tcgatttttg gtttcttgat atcaccacta gtaaaactca gcagatcttc
    18121 tgagaaatcc tttggcaagt aaatacctgc gtaatacttt ccggaacgga ctccgtcttc
    18181 taattgttct tttgaatcaa cgaattgcca tcctaattgt ttatttttat gaagcgattc
    18241 gatgacttgc tccccaatgg ccacttcttt accttgaaac tctgctggct tgtctgcact
    18301 gtaaacagca attggcagct ctccagtatt tccatatgga tcccataatg ctttgatgtt
    18361 aaaccacgca tatagcgaag ggatgatcat gatcgcgatg atcagaagtg ttgcaatcgg
    18421 gtttttgaaa atccgtttcc agtcaagcaa atataatcga agcgtatttt tgattgactg
    18481 catagttctc ccccttcttc ttttttcagc tgaattactt taccatgtat ttcatacttt
    18541 tttcaatcgg cttttttcaa aaaagtcgaa tttttggaca tatcacggca attgtctcat
    18601 tgtaatctct tacatattga gaaataatta aggattacag cctttacttt atcatgaaat
    18661 aaaagggaaa gataatttta tgccaaagtt tttatctatt atacgtatac gcaaaaaagc
    18721 taaaacattt tttgtctttg cccctacaaa aatgtttcag cttttttcgt tttttattcc
    18781 tgtatttctt atttttcgaa tgacaggatg attttcccag caggaggatg tccttcaact
    18841 agctgatgtg cttggatgac atgcttaagt gaagcagaca gattcattga aataaaaaca
    18901 tgaaaggctc ctttttggta ggctttgatt atgccagcaa aggcttctgc atctagatat
    18961 tcctttcttg gaacaaacga ttcataaaag ccttcctttt tttgccgcaa atctagatct
    19021 gggaggtcat ttaatgcaac atacctgccg cctggtttca tgatctggat gccggtttct
    19081 cctttgatac ttcctttcgt cgcatcgatt acaaggtctg cctgatcagc aaattgcaga
    19141 cctggatttg ttttatcata agcagcaaat gctgaagctc ctaatttttt taccttttcc
    19201 tcatttttac tggatgcact ggttaagatt cggattccct tttcatggag aagctggatc
    19261 agacttgacc cgaccgcacc tgatgctcct agtatcatta cagtatctgt cggctggatt
    19321 tccgtcaaat ggttgattag attataagcc gtaattcctg gcgtgaccat tccggctgct
    19381 tcttcccaac tcattttatc tggaattttt gctacttttg ctgatggcaa cacgacttct
    19441 tctccgtaag tcccgccgac tgcatggaca gctactcgat cacctacatg aacagttgtg
    19501 acatctgaac caatctctgt cacaatacca gcgccatcat tacctggtac ataagggaat
    19561 ttcaatgttc gtatctcttt catttctcct aaacgcaagg caacatcata aggattcaca
    19621 ctgaatgctt ttatttctac acgaacatgt ccagaaccga cttctctggg atgagcatcg
    19681 atttcttcaa aaacatcttg tgcttctccg taaccgttaa ttgcaaatct tcgcatggtc
    19741 accatctccc tttttcttta agtttacgtt tatgccttta ttttgacaaa aaaaatgtct
    19801 tttcgttttg gcgcatgatt caaaacaaaa tagttgtctt ttttcgcgta acgtgttaaa
    19861 ttatttatct aaaagcgtaa agattacgat ttacgctaat aaaaaataat tggaggaatt
    19921 tgttgatggc taaaaaatca aagattgcca aagcaaaaaa acagcaagaa acgattgaac
    19981 gctatgctgc tttacgccag gaattaaaag cgcaaaaaga ttacgaaggc ttgcgtaaac
    20041 ttcctttaga tgctcgtcca gaacgattga aaaatcgtga tttaatcgat ggacgccctc
    20101 gcggatacat gcgtaaattc gggatgtccc gtataaaatt ccgtgaatta gcacataaag
    20161 gtttgattcc aggagtaaaa aaagccagct ggtaatccaa gtctggctgt aatgtaaagg
    20221 aggagggcgc atggaccact ccttggatca tcaaaaaaga tacgttcgct tcttctagca
    20281 gaaatgctgg tactagaagc agacgtatct ttttttacgc acagctggtc cttttttata
    20341 tgtaaaggct gcatggttac ttcgctatat ttatttagta acaggagtca gtgcttcgat
    20401 acccacacta attttcaatg ctcggtcaac ttctgccata atgggtcgat ccaaatggca
    20461 gaccttttct ttcaatcttg atttatcgat cgttctgatc tgctccaaca ggataacgga
    20521 gtctctttct attcctgttc cagtagcttt gatcccaatg tgagtcggaa gcttaggttt
    20581 agccattttt gccgttatgg ccgcaacaat gatcgtcggg ctaaaatggt tacctagatt
    20641 attttgaata accaaaactg ggcgtgttcc gccttgctcc gatcccacga ctggagaaag
    20701 atcagcaaaa taaatatctc ctctttttac cataggatcc tccttattct tgatattctc
    20761 ttggtatccg ctgtcctaat ccgcaagcca cttcatagtg gatcgtacct aattgatctg
    20821 ctatatcctg catagtgatt tctttgtctg catttttgcc gataagcgtc acttttgttc
    20881 cgacaggaaa ttcttgaggc aatcggatca tcagttgatc catacataca cgcccaatcg
    20941 tttcacagta gttcccttct accaatagag aaaaaccctg catctttcgt ggccagccat
    21001 ctgcataacc gatcggtatc gttccgatcc actctgcttc aggagtgata tatgtttctc
    21061 catagccgat tccttcacct gctgggagtt ttttgacttg aatcaattca gaaaccagct
    21121 caagtgctgg ctgcaatgga taaacttccg gtagtgcgtg cccagaggga ttaagtccgt
    21181 acattgctac tccataacga atcatattgc cgattgtttc atcatgccat aaagccgttg
    21241 cactattgct gacatgtaca tatcgaggaa gttcgggaag ttttttcagc acttctataa
    21301 agcgttcttt ttgcagattc caatatgtat catctgcctg atctgctgta gaaaaatggg
    21361 taaataaacc ttcccattct aatacacgac tttctttgat gaatgcagct gcctctttta
    21421 cttcttcagg tgtacaaaat ccgatacgac ccatcccagt gtctgctttt agatgaatcg
    21481 aaagaggcgt ctctagctta cttttctcta aaacagcagc tgctgcttgc aaccattccc
    21541 gtgtacctgc agttactgat aaatcatgag caacagctac agtcagtgcg tcgtaaggaa
    21601 ccatattcaa gataaggatg ggctgagtaa atccagcttc tctcaactcg actccttcat
    21661 ctaaatttga aacacaaaag cccgaagctc cacctgcaac tgctgcctca gctgtttcaa
    21721 tagctccatg accgtatccg ttcgctttta ctactgcaaa caattctttt ccttgcggaa
    21781 gtcttgcaac ttcatttgct acattttcag ttatagcttt tttatgtatc actgctttcg
    21841 ttgggcggtg ccaagcgaca accatcgttt ttccttcttt ctagtcttcc aaaataattt
    21901 gtgcaaaagc tgtttcattt gtatgagtaa tactgaccca tacattgcct tcatgaggtg
    21961 aacgcgtcac aacaggctga ccattttcat tttttaaaat ctcgacatct tgaaaggtaa
    22021 cttttccgat cccagttccc caagctttag agaaagcctc tttgcaagcg taacgcccgc
    22081 ctaaaaattc tacttggcga tgaaaaggca aggactggaa tagtttcatt tcatcagagg
    22141 tcaagattcg tgcaatgaat tttggttttt cttcgatcag ccgagtgatc ctaggaagtt
    22201 cgactgcatc gatcccaatt ccttttatca tatgcttttc tcttttcaat aaatttagaa
    22261 cactctcatt ctaccaaatt ataaccattt tgccacaaat aagtccacaa ataacaaaaa
    22321 tgaaagtttc tcttaaaaaa gagaaacttt cattttatgt ttaatcgtta tttgaacgga
    22381 ttacaaatcc gcgtttttta tcattgtgac gtttaccgcc atctttttgg ctgttattat
    22441 ttttgctata accgcctttt gatttgtttc cacgataatt accgccgtca cgacgattac
    22501 ggttgtttcc gccaccacgt ttgccatttt tattgtatcc ttttttctgc attggcaatg
    22561 ggcgttctgg tgtgatcttc actggcactg catcagctgg atcttttgct gtcgttttta
    22621 gcaaaagtgc aactaaatct tgtgcagaat attcttctaa taatttatct gctgtttgca
    22681 ggtatttatc tagaccattt tctgcaagtt ttgtttcgat ttgttcaact gcagcaccta
    22741 attgaccttt gaatgcttct ttttcggttg gtggacgtaa agtcgtcatc cgttttttcg
    22801 tcaagttttc aatcacatgc aagtagtcca tttcatttgg tgtaacgaaa gtcacagaca
    22861 taccgccttt tccggcacgg cctgtacgtc cgatacggtg aacgtagctt tctggatctt
    22921 gagggatatc atagttgtac acatgagtga cacctgaaat atctaatcca cgtgcagcaa
    22981 cgtctgtcgc tacaaggata tctaaatgac cgctcttaaa tgaacgcaat acgctcattc
    23041 gtttttgttg agacaaatcg ccatggattc cttctgcacg gtaaccgcgt gcttctaatc
    23101 cgcgtgccaa ttcgtctaca cggcgttttg tacgtccgaa gacgattgtt aattcaggtg
    23161 tttgaacatc aaacaagcga gtcatgatat cgaatttttc gtattctttt gcgcggacat
    23221 agtattgatc gatcaagtca gctgtcattt ctttcgcttt gatcttcaca tgatgtggat
    23281 ttttcatgaa tttaacgcca atattcttga tagctggcgg catcgttgct gagaaaagta
    23341 atgtttgtct ttgatcagga acttgtgaaa tgattttttc gatatcttcc aagaagccca
    23401 tattcaacat ttcatctgct tcatccaaaa ctaatgtttg aacggttcca agtttcaatg
    23461 tgtggcggtt aatgtggtca agcatacgtc ctggtgtacc cacaacgata tgtggacgat
    23521 ctttcaagcc acggatctga cggccaatat ctgctccgcc gtaaacggct tgtacacgta
    23581 cttttttgtc gcgccctaaa cgatataatt cttcttgtgt ttggatagct aattcacgtg
    23641 ttggtgcgat aactaaacct tgtaattcgt gacgatctgg atcgattttt tctaacattg
    23701 gtaatccaaa tgcagctgtt ttccctgtac ctgtctgtgc ttgtccaata acgtcttttc
    23761 cagctaatgc tagtggaatc gtttctgctt ggataggcgt tgcttcttca aaaccagcgc
    23821 gttcgactga tttcaacaat tctggtgata attctagttc tttaaatttc aaatgaatcc
    23881 tcctatatgg ttgttaactg aggatgtagc ttttttgcta ccccgtcgat ttgttcggtc
    23941 aaagtgtatt gtttcttttt gacagtggcc acgcacgttt ttatccattc ttagcccctg
    24001 tggcaccacc gaaaaatcac tttgcgaagt ttaggcatta gaaaagccaa acgggtcgcg
    24061 ttcagcttta tcattattat gacatctggc ttcaacaagt tgtttctatg gcaaaaccag
    24121 tccaatttct cttcatcttt cggcaatagg ttattctaac atagtttttc gttttctgca
    24181 agtttacaga tttttatttc atttgctgaa gttgttctac cacttcaaat aagcccatgc
    24241 tgttgctgcc ttttagcata atactatctg ttgcttcaag attttgtttg atagcatcaa
    24301 tcaatttatt cttttctttt tcaaaataga acacaggtag ttgggggtat ttttggttca
    24361 attcttcttt tagtgcatgc atttgttccc cataaaggaa aatcatggcg aatttctcag
    24421 gatcgatatg ttcactcatt tgcgcatgca tatttaaaga ctctttccct aattccagca
    24481 tatctgctaa cacagcgatt ctgcgtcctt ttgttggcag atttttaaaa gtatctaata
    24541 ccagtcccat ggctgttgga tttgcattgt agacatcgct caaaatagct gcaccatttc
    24601 ctgccgttag ccattcggtt ctgttttgag tgatagaaac atgggcgagc ccttggcgta
    24661 tctcaggtat ggacagtcca aagaagcgcc cgatcgtata cgcaatcaaa gcattcgtta
    24721 cattataact tccaggcagc gggatcgtaa atgtttctcc ttctactaca aaatcggttt
    24781 gtgcttttcc ttttgctgtc acttccgcat gaacatcgcc atttccaata ccgaatgttg
    24841 tgactgtttg tactaatgtt gccgttaaag gtgtcagcaa cggttcatct gcgggcacaa
    24901 cgagtaatcc gtctgataca agtccgtcag tgatttccat tttggcttta gcgattcctt
    24961 ctcgcgaccc aagattttct atgtgtgctt caccgatcat tgtgattgct gcagcttttg
    25021 gttgagccat aagtgaaagt tccgtgattt cattggcgtg atccatgccc atttccaaaa
    25081 cgatcttttc tgtatcttgg ggcatgtgca aaatcgtgta aggaagacca atattattgt
    25141 tgtaatttcc ttgcgtctta tatgttttgt atttttcaga caagacagac gcggttagat
    25201 ctttcgtggt ggttttacca ttgcttcctg taattgcaac gacttctgcg cctacttttt
    25261 ccaagtaata ggttgccaat tgctgcatgg ctttcaaagg atctgctaca ggaataactg
    25321 gaaaattttt tggagcttgt tcaacaggca agctccaaaa tgaagcagat gctccgtttg
    25381 tgatcgcttg ctggataaat tcatgtccat ctcgcgtacc agcaagagga acgaataaac
    25441 ttccttcggt tatcttccgg ctgtcaaatt cgacattggt aatctttgtc agtgcagagc
    25501 attcgctgcc cacggcttgt gcaatttctt gtattgttag attcattgag atctctccta
    25561 aaaaaggttg tgaaaaaagc gtttggccta aacggcgggt tcgcatgact ctcacttcca
    25621 agtaaatttc tctattcgta tttagaagct agaatgaacg cggttacgca atcactccag
    25681 cctcttcttt atttctcttt attcattttt ttcaaaaaaa gattgacgct gatggtatcg
    25741 attcattcct aactggatca gttcttcaat caaatcaccg tatttcaagc ccatattttc
    25801 ccataagagt gggtacatac tgaactccgt aaatcctggc atagagttta attcattcag
    25861 gaataattca tttttatttg tcaaaaagaa atcgcaccgg ctcaatccgc ttccacctaa
    25921 catcgtgtaa gctaacttcg cgtactcttg cgctttttga taaacttctt ctggcacttc
    25981 ggctggaatc tgcatttcga ttttattatt gatatatttt gcttcataat catagaatgc
    26041 tacgtctttt acgacttcac caggcaaagt cgtccgaacg tcttcatttc ctaatacagc
    26101 aacttcgatt tcgcgcgctt caattccttg ttcaacgatt gctcgagaat catactgata
    26161 ggctgttgct aaagcatttt gcagctcttc tcggttttct gcttttgtaa tgccgacact
    26221 agaacccata ttcgccggtt tgacaaacat cggataaagc aaagaacctt cacattgatc
    26281 aaatactttt ttaggatttt ctttccattg attcttaagt actggtacat aaggaacttg
    26341 cggcacacca gcagcttgta aaatatactt ggtcatgatt ttatccatgg cacatgcact
    26401 ggtcaatacg cctgcgccga cataaggcat attcaatgtc tctaagaagc cttggatcgt
    26461 tccatcttcc ccgtttggcc catgtaaaac tggaaaaacg atggctcctt cttctttgat
    26521 ttcgcccgga ttgatcactt ttcctgtaaa gccttcctct gtctgtccac ttgggtccca
    26581 tgaaagatgc aagacatctt tgctggcagg tttttctgtt agtaatggac ctttgaccca
    26641 ttgtccttct tttgtaataa atacgagttg aacttggtaa taattataat aaatggcatt
    26701 taaaactgaa aatgcggaaa gaatggacac ttcatgctct gcgctgcgtc cgccatatag
    26761 taaagtaatc ttcaaaagat tgtcctcctg tattctaaat cgttcagtga tttactctca
    26821 tattttagca caaaacaaaa ataaacgaat aacttattta taaaaaaacg agccagcttc
    26881 taaaagaacg agcgtcattt attttttgtc agctagatta tttgtcccgt tttttataaa
    26941 aagttatgat aaagaaaagg agggatgatg atggcgcaaa caaatccacg cagccgcttg
    27001 gcagaaatca ttcgagtgtt catcaattac aatgtagtgc caaactttgt acagcaaaaa
    27061 aatcccgaac aggtaaaaaa agcctttgaa gaactaggcc ccaccttcat caagatagga
    27121 cagatgcttt ctgttcgaga agatttgctt tcttctgcct tcactcaaac attcaaaaca
    27181 ttacaagata gtgtacctag cgacacattt tcaacggtca aaaagacgat cgaaacagaa
    27241 ctttctcttt cattatcaga tatattcgat gatttttcaa aatcgccttt tgcctctgct
    27301 tctatggggc aggctcatcg tgccaagctg aagaacggtg acgcggtagt cgttaagatc
    27361 caacacccta acatcgccga agagatccga cttgatcttc aactatttga acgagcgatc
    27421 cctttgatca aatacattcc tgaaactagc gtagttgatc taaaaggggt actccaagaa
    27481 gtaaaacgtt ccttgatcaa tgaaatggac ttcttaaaag aaagtcaaaa tggcgaacaa
    27541 ttctatcaaa agaacaatgg ctggaaagag atccgcagcc ccaagattta tgacgctttt
    27601 tgttcgaaaa aagtgatcgt gatggaagaa atgtctggta aaaacttgaa tcatttaatg
    27661 aacgccgaaa acaaaactga aacttttatc actggaattc aaaacaagca gctgaaacaa
    27721 gaagttgcaa agcttttagt tgagaacttt atgaaacagg tgtttgatga tggttttttc
    27781 catgctgatc ctcatccagg gaatctgcta ttccatgtac taacaaaaga agaacagaca
    27841 caagctagcc gaaaaactga aacagtccat gaaaaagagt tcggttcctt tgcttttcga
    27901 gcctccactt ctgcagaaga ccctgttgcg ccatatacca tcaactacat cgattttggt
    27961 atgatggggc atctttctgc aggacttagg caaaaactca cacaagccgt tttagcgctg
    28021 tatacgaaag atgcttatcg aatcgaaaaa gcggtccttc gactttgtca gcaagaaggc
    28081 tcgtttgatg aaagtcggtt ccaccaagaa ctgacaagtt ttcttgaaca gtattatgat
    28141 tctcctattg atgaaatcaa cttgcaagaa gtattcacac atgtcgtgac gatttgtcat
    28201 caaaataatc tgcagttcga tcgtgatatc acgcttttgc tgaaagcatt tgggacatta
    28261 gaaggggtga tccgcgtcct cgatcctgaa gtttccctca tggaagtcgc ttcgcctttt
    28321 gctcaacatt attttctcac tcatctggat gtagaagata cattgaaaca aagcggatta
    28381 gacttattgg aagggatgaa ggctgcgcct aagatccctc aacagctcca ccatctatta
    28441 gaaatgtgga cttcgggaca aggaaaagtc aatttggaat tgaaaaagca agacaaatta
    28501 ttgagcagga tcgaaagtat gatcaatcgg cttgttttcg gtatgatttt agctgcattg
    28561 atcgtagggt cctccctgct tgtccaagca gcacctgtag aaaacgcaga ggtcgtttcc
    28621 ttattaggga tatttacgta tgctattgcc gcattcgtca ttattttttt ggcaatcgat
    28681 gcattgatcc aaatgtataa gaagaggaaa aagtagaaaa aggttgtgac agaaagaatc
    28741 agcttcaaga aataagaagg ggttttacat aaattgtttc tcaaattttt gtgaaaattc
    28801 ggcttatttt tcgaagaggc tacttctgaa acaccgagaa taaaaaatgt gaaaaagctg
    28861 ttctgcaccc agtaataaga acaatcaaaa agggaacatg gaacacattt atcctgtttc
    28921 cctgttccct ttttgatgta ttcgagcata aataaaatac cttcgttacc tactatcttc
    28981 tgtacttggt aaaccttagt caattgcctt ttttaacgct tgacgaaaag acatatgatc
    29041 tttctccgta aagggttttg gaccctttgt ccttatgcca gcttttctta actttccact
    29101 atgataacgt tgttctagaa gcgtgccgat attcgcttcg tcaaattctt ttccagagtg
    29161 atggaacact cgcacaccct tcggcaatac aagtgaagct aaaccataat cttgcgtgat
    29221 caaaaagtca ttcttcttaa ccataccgac gattttataa tccgcactat cagctccgcg
    29281 gtctacgtag acgatttgga catgattagc gtattctttg gtcgtataat ggtccacact
    29341 ggtcacgata accacgtcaa gaccatagga ttctcctaat tttatgacat cttcttttac
    29401 tggagaacca tctccatcaa tgaatagcct cattcttttt cgccttcttc cataaatgat
    29461 aaacagttac taatccgctc agtaaaagac caacattgat ccattttgcc aagataagca
    29521 gttgtacact ttctatcggc actgattcat ggttcagcgt gatcaataat agatggattg
    29581 gctctcccat ttcttttgct aaaacaaaca aaagcgtcat caataaaaac tggtggatca
    29641 cactcccttt attttgagta gtatacttga caacgatccg gcgatccatt ggaatagctg
    29701 tatcagtttg ataatattcc ttatttagcc agctgcctgt tactacgtgc cagaaactaa
    29761 gcagaaagac acctatcgca aaaccatttg gaatcaagag gaccaataaa gaagaactca
    29821 gtccaagcaa ttgcatagcc aatggagacc atgttaaacg tttcaaaatc catggtccga
    29881 ctatttttgc tgcaatcaag cctgctgcat aaggcaaata cataaaaatc gaaagttttt
    29941 ctaatccgta cagtatgcca acataaaaac tgctaaataa aaaaaggaaa ttccctagca
    30001 ttccatttag aaaagtaaac agatttagcc agcttggcaa cttccattcc ttcttctggt
    30061 gtcctaaaac aaacacgaac aagatgaaca gcagcaagaa accataaata gcaagatcaa
    30121 aaagcctttc atcgaataac aatcgggcat ttctcaaaag aaacaataag ccaaagaata
    30181 tcaaaaataa aacaagctct cgcgtagcta ccagatttct tttgatgtct ttgaaatcca
    30241 gttcgtaacg cggataatga ctaaccgtat ggtaggccat gacgtaaaaa agtgtataaa
    30301 tagtaaagct tgctgcaatc tgagtcggtg caggcaactc aatcgcttga tacaggagaa
    30361 atagccagat agctgcaaat aagtactttt tcccatccat attgataaaa ccttgcgtct
    30421 tttcgtgaaa attgaccgtg gtattagcag gtacaagcca tgctgcactc agccctagca
    30481 aaacacttga aaaataaaat aaaggaaaat aaaatacgcc taatattcca agcaatgaac
    30541 cagcaccacc aatcagcaga gcgatcatca gcaacgtgta actatctaga ccaaatcgta
    30601 gactgttgac taaaaatagt ccagtcatcc gaaaggcata aaacagcgta aatggcaaaa
    30661 tcgtcagcca attatgcgag tctgttagtc ccaaaaataa aagataagga ataaaaataa
    30721 ccgtgttact taagataaag ggcgttgttt gtgtaaaatt acgcccaaat cgtttgagtt
    30781 tttcgaacat gacaatggct ccttaaacag tcttataact aatctgctct tcgattttag
    30841 cattaaaggg gaaataaacc aattttacag aatatattct tgtaaaaaaa aatacagaaa
    30901 gaagcataag cttctttctg catttttacg gtacttgatt actcaagcag acaagccctt
    30961 ctccacaaaa gtcttgcccg acacccctgc atccggcagg tgataaagat agaaatcaat
    31021 tatcctgtgc ctccaaaatc aattaggagc tctgtaaacc agagtccttc tcgacccgtc
    31081 gcataaattt actttaacac agttcctatg tttatgcgag agcttttttc attttataat
    31141 cgaccatttg aaatccttga ccgatatctg aaataagttc ttctgtaatc tcaaatcctt
    31201 catgcttata aacctcgatt gcttgatgat tcccctgatt cactcgcaaa aagatctctc
    31261 tttcctttgt ttgcgcagca agttcttcat accagcgaaa aactgaagaa gtcaatcctt
    31321 gaccacgtac tttatttagc aaatataatt tacttaaata aatttttcca tttatctctt
    31381 cataagcagt gtaaccgaca gtcttttctt cgctttttaa taaaaagtag gacacacctt
    31441 ctgtcagttc tttttgaatc tgtttttttg actgataagt tttcagcatg taatccactt
    31501 gtttttgacc aatgatcggc acaaaaactt ccggccatac ttcttgtatg actgccatca
    31561 gctcatccag ttcattttct gttactttta ttttttccat acacccacgt ccttttttac
    31621 attataaatg accttgcgct tgatggaata aaaagagcat gatcatgcta tacacaccca
    31681 ccgaccacgg tttcaagaaa atcacaatct gcataaattc cctaaaagat aatttcgtca
    31741 aaccagctac tagacagatc aagtcgtctg gcgcaaaggg aagcagcaag gtaacaacta
    31801 gtactttttt aatatctttc gtttttcttg tcagcaattc atcaaatttc tgatactttt
    31861 ttggcgataa aataagctgg acaaaggcta cgccatagta acggacaagc aaaaatccga
    31921 ttgcttcccc aatcactagg ccaatacaac tatataaaag cccaaatcca ttgccaaaca
    31981 tcagcatgcc cgctactgag gagatccctc ccggcaaaat aggaatgatc acttggatca
    32041 cttgcaacag aacaaatatc atcactgcat acttgccaaa ttgctggata aacgcttgca
    32101 aagacgtgct cgatcgaaaa atcccatgat gataagcata aagaatcaac acaaagaaaa
    32161 aaaacagacc aataatgggc atgatctgaa gacatttttg taaaactgat ccttttttag
    32221 acatctatat tccccacatc ttttttcatt tattaaaact gcctcct
//
LOCUS       DAFLVO010000029        31290 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.029, whole genome shotgun sequence.
ACCESSION   DAFLVO010000029 DAFLVO010000000
VERSION     DAFLVO010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.029"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            147..1016
                     /locus_tag="L1U99_001368"
     CDS             147..1016
                     /locus_tag="L1U99_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HBN1211918.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1225..2250
                     /locus_tag="L1U99_001369"
     CDS             1225..2250
                     /locus_tag="L1U99_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBN1211919.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2289..3239
                     /gene="manA"
                     /locus_tag="L1U99_001370"
     CDS             2289..3239
                     /gene="manA"
                     /locus_tag="L1U99_001370"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBN1211920.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            3333..5036
                     /locus_tag="L1U99_001371"
     CDS             3333..5036
                     /locus_tag="L1U99_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1211921.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5038..7071
                     /locus_tag="L1U99_001372"
     CDS             5038..7071
                     /locus_tag="L1U99_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBN1211922.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7082..7522
                     /locus_tag="L1U99_001373"
     CDS             7082..7522
                     /locus_tag="L1U99_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1211923.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(7722..8849)
                     /locus_tag="L1U99_001374"
     CDS             complement(7722..8849)
                     /locus_tag="L1U99_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1211924.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLLDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(8852..9529)
                     /locus_tag="L1U99_001375"
     CDS             complement(8852..9529)
                     /locus_tag="L1U99_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1211925.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9793..11559
                     /locus_tag="L1U99_001376"
     CDS             9793..11559
                     /locus_tag="L1U99_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HBN1211926.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11574..12011
                     /locus_tag="L1U99_001377"
     CDS             11574..12011
                     /locus_tag="L1U99_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1211927.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12024..13175
                     /locus_tag="L1U99_001378"
     CDS             12024..13175
                     /locus_tag="L1U99_001378"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBN1211928.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(13237..13935)
                     /locus_tag="L1U99_001379"
     CDS             complement(13237..13935)
                     /locus_tag="L1U99_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HBN1211929.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(13928..15280)
                     /locus_tag="L1U99_001380"
     CDS             complement(13928..15280)
                     /locus_tag="L1U99_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HBN1211930.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(15503..16903)
                     /locus_tag="L1U99_001381"
     CDS             complement(15503..16903)
                     /locus_tag="L1U99_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HBN1211931.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            17064..17801
                     /locus_tag="L1U99_001382"
     CDS             17064..17801
                     /locus_tag="L1U99_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HBN1211932.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            17926..18405
                     /locus_tag="L1U99_001383"
     CDS             17926..18405
                     /locus_tag="L1U99_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HBN1211933.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            18402..19169
                     /locus_tag="L1U99_001384"
     CDS             18402..19169
                     /locus_tag="L1U99_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211934.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            19399..19968
                     /gene="lepB"
                     /locus_tag="L1U99_001385"
     CDS             19399..19968
                     /gene="lepB"
                     /locus_tag="L1U99_001385"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBN1211935.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(20072..20674)
                     /locus_tag="L1U99_001386"
     CDS             complement(20072..20674)
                     /locus_tag="L1U99_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBN1211936.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            20780..21249
                     /locus_tag="L1U99_001387"
                     /pseudo
     CDS             20780..21249
                     /locus_tag="L1U99_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            21355..21939
                     /locus_tag="L1U99_001388"
     CDS             21355..21939
                     /locus_tag="L1U99_001388"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBN1211937.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            21942..23015
                     /gene="prfA"
                     /locus_tag="L1U99_001389"
     CDS             21942..23015
                     /gene="prfA"
                     /locus_tag="L1U99_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBN1211938.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            23008..23847
                     /gene="prmC"
                     /locus_tag="L1U99_001390"
     CDS             23008..23847
                     /gene="prmC"
                     /locus_tag="L1U99_001390"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBN1211939.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            23840..24019
                     /locus_tag="L1U99_001391"
     CDS             23840..24019
                     /locus_tag="L1U99_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211940.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            24041..25066
                     /locus_tag="L1U99_001392"
     CDS             24041..25066
                     /locus_tag="L1U99_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBN1211941.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            25257..26501
                     /locus_tag="L1U99_001393"
     CDS             25257..26501
                     /locus_tag="L1U99_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBN1211942.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            26654..27601
                     /locus_tag="L1U99_001394"
     CDS             26654..27601
                     /locus_tag="L1U99_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1211943.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            27735..28364
                     /gene="upp"
                     /locus_tag="L1U99_001395"
     CDS             27735..28364
                     /gene="upp"
                     /locus_tag="L1U99_001395"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBN1211944.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(28503..28745)
                     /locus_tag="L1U99_001396"
     CDS             complement(28503..28745)
                     /locus_tag="L1U99_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211945.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            28866..28938
                     /locus_tag="L1U99_001397"
     tRNA            28866..28938
                     /locus_tag="L1U99_001397"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:28899..28901,aa:Thr,seq:cgt)
     gene            complement(29057..29695)
                     /locus_tag="L1U99_001398"
     CDS             complement(29057..29695)
                     /locus_tag="L1U99_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBN1211946.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(29818..30450)
                     /locus_tag="L1U99_001399"
     CDS             complement(29818..30450)
                     /locus_tag="L1U99_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBN1211947.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            30801..31100
                     /locus_tag="L1U99_001400"
     CDS             30801..31100
                     /locus_tag="L1U99_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBN1211948.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT        10686 a         5455 c         6296 g         8853 t
ORIGIN      
        1 tttataagag tttttactca ttaatttaca aaaaacaagc aaaatgcgaa ttttctcaca
       61 ttttttttaa caaaatcaaa gttattgctt gaaagaagaa gaatccatcg ttaaaataaa
      121 gcttgacgta gaggggagca agaaatatga aagattttca attgggggct gccacctatt
      181 taaaaagtgt agccattcgg gtgaaagacc gagataaaat gattgatttt tacaagaacg
      241 ttgttggctt tgatttgaaa agagaagaaa acgaattagc cattttagga acagaagaag
      301 ctggaagtga aatgttgctg ctggaagaaa gtcctagagc gaatgatcac atgggggtga
      361 tcaaaaagct gaaccgtttt tcattgatta tccctagcac agaagaaatg gcagatatcc
      421 tttgtcgtat ccgtaaaatg aattatccaa tcaaagaagc tttagaagat catggacgta
      481 tggggatttt gctcgtagac ccagaagaga atgaattgga aatttaccat gaagagaata
      541 agaacgacca aagagaaatt ccagaaacaa tggatcaaga agcattatta agaaaatctg
      601 aagaaaaatt cagtaaacta tcaacaggtt cttattttga aaaaatccat ttaaatgtta
      661 ctaacttaac aaaagaacgc caatttctta atcatgtact tggtttgaag gtacataatg
      721 aagaagaggg catccatgta ttgaatgaag gagatttcca tgttggtttg acagaagcta
      781 gcggaggcgc aattgatttg cctacagatg aagtgattgg acttgatttt ctgaaattca
      841 tgatcgatac tgaaagcatg gaaggactga ttgctcactt gcagcaacta tcagttgatt
      901 tcttcttaga caaaaagcac acagtactca caatctatga tgctatagga atcgaatggt
      961 ggttcgtcag tgagccaaaa gaaaagaata aaactgacat tcgatgcgac gcttaacttt
     1021 ttctttctta acgattgtcg catgtctcgt cattttatga acggtcatac tatcgcttat
     1081 tctagagata gaaagagaaa atagtatacc gggggaaact gcgcggtttt tcgcgcagtt
     1141 tttttgtgta aaaaaggttg attcctcata gattaagctt taagcttgga ctgtaagaat
     1201 ctgatagaaa agcaggagaa aaagatgtat ccacacacga aacagcttat tttgaaaaag
     1261 atggaagaag gattttatcc aggtgtagca gtcgccttca taaaagaaaa tcaagtagaa
     1321 acatttacag ccggctttgc ccaagtcgtt cctgaaaagc agctgatgac agaagatctg
     1381 ttgtttgatg cagcctcact gacgaaagtc gttgcaacca cttcattagt tttacgtcta
     1441 ttagaagatg gaaagataga actcgatcaa ccgcttcata aatatcttcc tgaatttgaa
     1501 aatcagacaa tcactttgcg tcatttactg acacatactt ctgatatcaa aacatggata
     1561 ccaaacagag ataagctatc tcaggaagaa ttgatcgccg cttatttgaa gctagaacca
     1621 ggtgagcaac taggaaaaga agtaaaatat acagatgccg gtacgattct tcttgggttg
     1681 atgctagagg aaatttacca agaaactgca gtggaaatct ttcaagaaca agtattggaa
     1741 ccattaggaa tgatgaacag cttatttctt ccttttcctt ccaaaaaaat cgttcccaca
     1801 gaacaactgc cttcgggtga ggttttgcgt ggacaaactc atgatccgaa agcaagagtt
     1861 ttggctgaac atgcaggtaa cgcgggtctc tttattgatt tgaaagacag cattactttt
     1921 gtccaaatgt atttgaacaa gggaaaaatc cgtaatggtc gttttttaga agaagagacg
     1981 attgattctt tactgcaaga tcaaacaccg aaaaaaaatg gctatcgttc tttaggatgg
     2041 gacttaaaaa aggatgtaga agacggtcat gcgattcttt ttcatactgg ttatacaggt
     2101 acgtttttct tgattgatat aaaaacacaa gaagcgttga tatttttgtc aaatcgcgta
     2161 catcctgtcg atcatcgtgc ggagtatctc atatgtcgag atgaaattgt tgaaaacttt
     2221 ttgaaagaga aagcggtatt accgaaataa tgctataata gctatgaaaa atgagaggag
     2281 tttgaattat gcaggaacct atgtttttaa aaccagtttt tcaagaaaaa atttggggag
     2341 gaagtcgttt acgttcagtc tttggttttg atatccctaa cgataaaatc ggagaagatt
     2401 gggcgatcag tgcgcatcct catggtgtca gtgtagtaga aaatggcgaa ttcaaaggga
     2461 aaagattaga tgaactatgg tcagaacaca aggaattgtt tggccatcct tcagaaccag
     2521 tgtttccatt attgatcaag atcttagacg cagaagatga tctatctgta caagtacatc
     2581 cagatgatgc ctatgggatg aaacatgaag gtgaattagg aaaaactgaa tgctggtata
     2641 tcatcgatgc tgaacctggt gcagaaatca tctatggtca tcatgcaaag acaagagaag
     2701 aactagctga gatgatcaaa gatgggcgct gggatgacct tttgaagaaa gtaccagtta
     2761 aaaaaggtga tttcttttat gtaccaagcg gaacgatcca tgctattggt aaaggaatca
     2821 tgattttaga aacacagcaa agttctgaca cgacttaccg cgtgtatgac tacgacagaa
     2881 aagatgcgca aggacaaaca agagagctgc atatccaaca atcgatcgat gtaacaactg
     2941 tccctgcgaa aacaccagaa ttacaaatca aagaagtccg aaaagggaat tcatcgatcg
     3001 tcacttattt agaaactgag tttttcaatg tatatgagtg ggatattaaa ggaatcacat
     3061 ctttcaaaaa acaagcccct tatacattga tgacggtaat cgaaggagca ggagaccttg
     3121 tcgttgacgg aaaaacatat ccattagaaa aaggaacaag ctgtattatt ccaaatggcg
     3181 tttctgagtg ggcggtccaa ggtgaactag caatcattgc gtctgaacca ggcaaatagt
     3241 tcccagatag ctgaaagcag cagacggttt ttcgtttgct gctttttcta cataaaatcc
     3301 gtccatcaat aaatagaagt ctggtgaaaa agatggaata caaatggaaa gcaaacaaca
     3361 gcagtcgcgt gtctatgaaa caactgagaa aagctggaca tcacttaaat gaaatgatca
     3421 tgccaaatct aagtctgttt atcgcttggg gaatcttgtc attagcaaca aaaggtgtgt
     3481 ctggcgattt gcacaccaca ttagaagagg tatgccattg gatgatccag ctgcttttac
     3541 ccatcttgat cagttattca ggcgggaaat cggtaggggg acaaaaaggg gcagtcgccg
     3601 gtgcaattgc ttctttaggg ttgatcgctc gttccaatgc tccacaaatc gtaggagcga
     3661 tgattatcgg gccgcttgcc ggcatcgtat atgaacaatt tgtttctaga ttccatgtga
     3721 aattcaaggc tggatatgaa atgcttgtca gcaacctact agtaggactg actggtagcg
     3781 ttatttgtat aattggaatc gtttttattg aaccagtttt aaatagtgtt cacttgttgc
     3841 tcgcctccgt tgtgtcttgg ctagtcacaa tgaatctgtt accacttgtc agtctgatct
     3901 tagaacctct aaaagtacta tttttcaata atgcaatcaa tcatggtgta ttgacacctt
     3961 taggaatcga attctcacaa acagtcgggt actcttcctt atttttgatg gaggcaaatc
     4021 ctggacctgg tttagggatc ttactttcta tcctttgttt tgcagaaaaa caggaaaaag
     4081 taaatgcgag tggagcattg atgatccatg cgattggcgg gattcacgaa atctattttc
     4141 catttgtctt gctgcgaccg tatctatttt tagctgtaat ggctggtggg gcaagcggca
     4201 cgttgatatt tcaatggtta gatacgggat tagctgcacc tgtatcgcct gggtcactac
     4261 tcgtgatttt tgccaatgcg ccttatccac aactagctgg ggtaagtata gggatagcaa
     4321 tcagtacatt tgtgaccttc atttgtgcag cgatactatt gaaattacca aataaagaaa
     4381 aagagaacaa aacggtcaaa gaaaggggag aaatcttgga accatctatc attcattccg
     4441 tcatttttgc ttgcgactca ggtatgggat caagtgctat gggagccgcc ctgctgaaaa
     4501 agaaattagc agcagaaaaa atcgatcttt ctgtcggata cagctctatc tatgaattga
     4561 ataaccaagt aaatcagctg gttatcgtgc aacatgaact agcgggtctt gcaagagaaa
     4621 aagtacctca aagtcaaatc tatgtactgg atcacttttt ggaaacagat atcttgctgt
     4681 cacgaataaa agaagcgatc caatttccaa agcgggaaga aaaaaaagag atagcagata
     4741 tcacagaaca aaaaacgtcg cctgctaata ttgtattttt gtataaaaac aacagacgcg
     4801 gctcacaaac tatgggcatg acgattttaa gtcaattagc aaaaaaagcg aaaaaacagt
     4861 ttgttatctc aaaagaatca atagaaaaaa tcaaaatcca agaagaaacg atttatatcg
     4921 cacaaagaga actagctgta actgaacagc tagaagaaaa gatccctcgg ctagttctag
     4981 ttgaacattg ggtagctacg aatgaatacg aaaaactcgt gaagggagaa atataagatg
     5041 tatttatcgc ccagagaaaa acaattatta gcagaatttc tcagtagccc gtcacctgta
     5101 tctatccaaa aaatgatgaa tttattgaag gtcagtaaac ggactattta ccgcgaatta
     5161 gataatcttg aagtctcatt gaaatcggta aatgcttctt tgaaaaaagc agctagaggc
     5221 tcatttgtca ttgaggcatc agaagaagta ttagagcaat taaaagaaaa tacagatggg
     5281 aaaagtaatg acttatccac tgctaaacga caacacgcga ttttagccga gttgttactg
     5341 acgacagagc cgttgagtct tgctcatttc atggaatcat atcgcatcag taataccact
     5401 ttttatgcag atatcaaaca gttggaagaa agtattcgcc aactgccttt ggaaatcatt
     5461 cggaaccagg gatacgagat cgaaggaccg gaaaaatacc gccggcttct gacagcgaat
     5521 gtattagaat tagaaatcaa tgaatatgaa ctttttcata gtatttcttt cgatgcatca
     5581 ctgaattatt tttttcgatt cgttgatccg caacatctat ctcttgcacg caaagtaatc
     5641 ggggaagaat tgatccaaaa aaagaccaat ctaagtgata gaaagcttga acatttggtt
     5701 ttgatgctga cattgacgat ggagcgtgtg acgaaaaatc atttactgac aaatgagaca
     5761 tataatagtc tggcaaacaa agaattacta cagacagcta aacgattgtt ttcacggatc
     5821 gcttctgaga caaaacaact ttatccagta aatgagatcg tcttttttgc aggattatta
     5881 aatgacttca cgaactcatt tgatcagaat ttctttgaag agacgttcga tacacagctt
     5941 gcttatttag taaaacaact gattcaagaa gtaagtgaag agacgaatgt ccatttttat
     6001 gaagatgaaa ctttgtacaa aatgctgttg actcatttat ctggtgtgtt ttcaagagcc
     6061 gttttacaag aagagacact gaccaatccg attttagaaa aaatcatggt tcaatacgag
     6121 gaagttgcga atgcaatccg taaagcagta gagcggattt ttcaagaaaa aaaattatcc
     6181 gaagaagaga tcgcttatat ggtccttcat tttgcgaatt cattggaacg aagtccgaaa
     6241 gaaagcaata tcagtattgc aggattttcg ccaagtggat tagcttctac tagcatgttg
     6301 gaactacgat tgaaaaggta ttttcccttc atccaacaaa ttcatttcta tcggattgct
     6361 gatttaaaaa aaatcgattt acaagaagaa tatgatgttg ttatttctac atctatttta
     6421 ccaggatacg gtggaaaata tattttagtc tccccgctac tgctagaaga tgaagtcaag
     6481 cagctaaaag aagctttttc gcatattgag aagaaaaaaa ggcaaaaaat tacgtataac
     6541 agcaataacg agtggatgat agaagatact tatgaggaaa caatgcattt catggatcaa
     6601 atcaatcaat tactcggtcg tttttttatc caagaactgg ataatcctga gacgatttcc
     6661 gaaacgattc gcagcttatt tccttatttt cctgaaggac tagtaacgga tgaagaggtg
     6721 gttcatcgcc ggctgcttaa gcgatatgaa caagcaccta tcggtattcc tcatacaaat
     6781 atggggttat tccatacatc cagctcattg atttctaaac cgatcttttg tattttcaat
     6841 ttgaaacatc cgttgaccat tgaagggatg gatagacagc cagtcgattt gtcccgtatg
     6901 ttagttatgc tggcgccttc gccaatccaa gaaaaagacg ggattctttt aggaaagatc
     6961 agtggagcaa tcatcatgaa tgacttgaac accgagatct tccgctcagg aaataaagaa
     7021 atcgtttatc agttgttagc gaaaatcctg attgaagaaa taaagaaatg aaggtgaaaa
     7081 gatgatacag ctaccagcag aaaaaatatt gctcgatcaa tcctatcaaa attggaaaga
     7141 agcgttgacc gagatcggcc agtggatgac ccaacaaggg ggaatcaaac cggcatatat
     7201 ccaatcaatg atcgaaagac aagaaaaagc gagtgtctat atcgggaatt tcgtagcctt
     7261 gccacatggg actgacaaag atgaagaagt agtagaagaa ggaatctatt tagtccaagt
     7321 gcctgatggt gtggactttg gaacaaaaga ggaaccaaaa atcgcgacac tcttatttgt
     7381 agtggcttta aaaaaagaac atcagttagc ggtgctccaa gatttagcct ttttctgttc
     7441 agacatcgac caagtaatgg cgctcagtga tgcggaaacc attgaagaag tccaaatgat
     7501 ttttgaacat ggacatatat aaccaatgtt cacagtaaaa aaagctgcct tgcatcaagt
     7561 aataacttca accaagataa aaataagagg agctattttt gttgggaggt tcttattact
     7621 gcggatgcaa gcttttgaaa actatttatt ctagaaaacc gtttatttga aataggggac
     7681 ggtgacaagg tttttgtcac cgcccctatt atttttgtgt tttaatagct cttttttata
     7741 tagatagtgc ccatacctat gaataataaa acgatactcc atataccaag tgtcaagata
     7801 ccattcatga aagtaacctg ttctgaagct agtggcgaga aaatatctcc tcctatgatc
     7861 acattttgaa aatcaacata agaagttggc aagtaatgac tgattgattc tatccatcca
     7921 atcgaagaaa acaagcgata ctctgctaag aaaagacaaa gaagtgtacc taaaagattg
     7981 actagagaat gttcaaataa agcagataga agaaaactga ttgtacttaa aaagagcacc
     8041 cacaacaaca ggaacagaaa gctctggaaa agatactcat acatcggcag gattcgtatc
     8101 tcctgaccaa tgatcgttcc tacaggataa cggaagtctc ccaaaccatt tttgattatt
     8161 actagtatag agacgatcaa aaatggcatc acgagactta gcatagctgc accataataa
     8221 atggtaaaac ggatgctatg tttctttacc atactatcca gtaatagatt gactagagag
     8281 attacctgct ttcttttttc ataagagatg atggaagaaa gaaacaaggc ggttatacat
     8341 aaaatcaaaa aactagaaat cattcctgaa aaaatatttt cgtagtaatt tgctaaagag
     8401 agatgcgctg gcaagtcaaa aatagaatat ctttggatct gatgttcttt catataacgg
     8461 agcaactcga cacgtttttg ttgttcaatg attggaattc cttgtctttg accagaaatc
     8521 agtcgatcca gtatatcttt ttcataatga taagttgctt cgaccatttg ctggacattc
     8581 cctgtgtttt ttgcatgtaa gattgcttcg atcagtttgt tgcttttctc taaactttcc
     8641 acaaattctt tctcattctc atcttctttc aacgtttcaa tcaaacgttg catctcttca
     8701 tagttatgat tcagttcatc gaattctgta taagcaagtt tatgatcaaa aaaaagtggg
     8761 aatgcaaaga gcacgaccaa caatagagga aataaaaagt ttactttgtt ttttagtaag
     8821 agattgcgtt caaatgtaag taaagacata gttacacctc atataattta cgataaatag
     8881 ctaaaatctc ttccatattt gaggattctg tgacgatttc tccatttttt agaaaacatg
     8941 ctttagaaca aatcgattgg atattcgcga tagcgtggga agaaagaaga atcgtcttcc
     9001 cctctttctg ccattgtctg atgaggctat tcaagatatc aatacttcct gggtctaatc
     9061 cgttcaacgg ttcatcgaat aacatgacag atgaatcact gatcaagtaa gcagcaagca
     9121 agacatgttg tttcattcct agagacattt ttccaatcgg caaagtaagg tactcagtca
     9181 tcttcaatcg ttggaaaaca gtttggcatt ctactttgct ctgccaatag tatttgatca
     9241 aagtcaaata atcaacagcc gatagatagt cggataactg attcgttgat tctagaaaaa
     9301 agaaagaccg gcgataatct gtataagcag taggagagat gttgtgaagg gacaattgat
     9361 cataagttgt tggcagcagt tgggcaatgc cattcagcaa agttgttttg ccaaatccgt
     9421 tcggggcaat caaagcagct acttctcctg attctactaa aagattcaat tgtcgaatca
     9481 cacgtttttt accacgtttc atgttcatgt ttttgatcag taatgtcata gataggcctc
     9541 caatataaaa tttaataaca taatagaatg gaaaacatct aaattaaatg ctaacaaaag
     9601 ttattgtttg catattataa aaaaattaaa ataacagttt tatttaaaat tgaagttttc
     9661 tgataccgaa atctttttat tttgctgaca tactcaaacc tttggcacaa agtttcgtgc
     9721 caaagtacga ctatttctct ttttagtaag cggatacaat tagagtatca aaaggagaga
     9781 gggagagaca aaatggaacg gacgattccc aaaaacaaca tttcgctaaa agcgagggta
     9841 caaaaattag gcagtacttt atcaagcatg gtcatgccaa atattggagc actgattgcc
     9901 tggggtgtat taacggctct atttatccca gatggttatt taccaaatga ggctttcgct
     9961 accatggtaa gcccaatgct aacttatctg attcctttat tgatcggtta tactggcgga
    10021 aaagtaattg ctggtgaccg cggatcagtt gttggggcaa ttgcaacgat gggtgtgatt
    10081 gtcggaacag atattccaat gatgctaggc gcgatgatca tgggacctct tggtggatat
    10141 gccatcaaga aatttgatca gctattccaa aaacggatca aatccggttt tgaaatgcta
    10201 gtcaataatt tttcagcagg tcttatcggt tttggattag cgttattagg tttttctgcg
    10261 attggtccag ttgtcgatgc attgactcaa gcaatggcaa aaggtgtaga gatcatttta
    10321 tctgcccatt tgattccatt gacaagtatt tttattgaac cagcaaaaat cttatttttg
    10381 aataatgcaa tcaatcatgg gattttgaca ccattgggaa ctgaacaagt agcagaggct
    10441 ggaaaatcta ttctattctt gcttgaagca aatcctggtc caggacttgg cgtattactt
    10501 gcttttactt tgtttggcaa aggagcagca aaatcttcag caccaggagc catgatcatt
    10561 cactttttag gcgggatcca tgaaatctat tttccttacg ttatgatgaa accgttatta
    10621 ttcttatcag ttataggcgg aggaatgtca ggaagtttca ttttccaatt gatggatgct
    10681 ggactaagag cgccagcttc tccagggtcg atcattgcga ttctagcgat gacaccgttc
    10741 aattcttacc ttcctgttat tttgggcgtg attgttgccg cagctgtttc gtttggtatt
    10801 tctgcagtaa ttttgaaagc ggatgcgaaa gatacaaatg aagacttcga aaaatctgtt
    10861 caagagacaa aggcagctaa gcaagcttcc aaaggtgccc aaggtattcc tcaaggagct
    10921 acattctctg gcgtacaaaa aatcattttt gcttgtgatg caggaatggg atcaagtgcg
    10981 atgggcgctt cgatcttgag aaaaaaagta caggaagcag acttgcctca aacggtgacc
    11041 aatcaagcaa tcagccaact gacagatgac tcgaatacat tgatcgttac tcaggtcgaa
    11101 ctacaagaaa gagcaaaaca aaaagcaccg agcgcgcgtt ttgtctcagt agaaaacttt
    11161 ttgaattcac ctcgatatga tgaaatcatt caagaattaa gcagcaagca gaaaacatca
    11221 gtttctgaaa ttgagaatga gccagcagaa gagtttcttt cagcaaacat caaacaaatc
    11281 aaagagattc tacttgtcca cgatgatcgt tccggatcag caacaatggg gatgaccgtg
    11341 ctcaaagata tattagacaa gaaccattta actatcccgt taagaaaagt caatatccaa
    11401 gatttaaaag atgaacctga ttcactgatc gtagccaaag aaagtttagc ggaaaaagta
    11461 cagatggctg cacctcaatc cattcattta tcagtcaaca gcatggtcaa tccgcaaaaa
    11521 tacgaatcga ttgcacaata tttgaaacag acagcttaag ggaggaaaac agcatgcaaa
    11581 gtttgccatt cgacatgatc gagctcaatc gatcttttaa aaccaaagaa gaagcgatcc
    11641 gctattgcgg tcagatgctt gtagaagcag ggtgcgttga tgaggaatat atcgatgcca
    11701 tggtagatag agacaaaatg ttatctgttt atatggggaa ttttatcgcg attcctcatg
    11761 gaacagatga agcaaaaaaa tatgtgaaaa aatccggcat ctgtgtcgtt caagtaccag
    11821 atggtgtaga ttttggtacc gaagaagaag aaaagattgc gactgttttg ttcggtattg
    11881 caggagtcgg agatgagcat ttgcaacttg tacagcaaat cgcactttat tgcagtgata
    11941 tggacaatgt tgtccagcta gcagacgcgc tcagcaaaga agaagtaacg gaaaatctag
    12001 caattgctta aggagagaga aaaatgagag cagtacattt tggtgcagga aatatcggtc
    12061 gaggatttat tggagaggtt ttggcagcta atggatttga gattactttc gtagatgtga
    12121 atcacacgat cattgatgct ttaaatgaaa gaaaagaata cgaaatcgaa ttagcagatg
    12181 aatcaaaaga aaaaatcact gtaaaaaatg tcaaaggaat caacaatcaa acaaatccag
    12241 aaaaagtaat ccaagaaatc gctgaagcag atttagttac taccgccatt ggcccgaata
    12301 tcttaccttt tattgctgag ttgattgcaa aaggtatcca agaaagagaa aaggaaggaa
    12361 gcacaacatc tttagatatc attgcctgtg aaaatatgat tggcggttca gcatttctag
    12421 aaaaagaagt gtataaatat cttccggaaa catcatttac tgacaaatat atcggctttc
    12481 caaatgcagc agtcgatcga atcgtcccat tacaacacca tgaagatcct ttattcgtcc
    12541 aagtggaacc tttcaaagaa tgggtcattg acgatagcca aagaaaaaat aaaaaaatcc
    12601 aattaaaagg ggttttatat gtagatgatc tagaaccata tatcgaacgc aaactattta
    12661 gtgtcaatac tggtcatgcg actgtcgctt atacaggtgc cttgttaggt taccagacca
    12721 ttgatgaagc aatgcaagat gcgttagttg tggcacaatt aaaatcagtt ttgcaggaaa
    12781 caggaagttt gctgattgcc aaatgggggt ttgatgcaga gcagcatcat gcgtatattg
    12841 aaaaaatcat tcatcgcttc caaaacaaaa atatctctga tgcgatcaca cgtgtcgctc
    12901 ggacaccatt acgtaagtta ggttatcaag aaagatttac acgtccagtg agagaactac
    12961 aagaacataa cttgacttgc ccacatttga cggcaacaat ggggattatt tttaattact
    13021 atgatcctga agatgaacaa agccgtcaat tgcatgaaat gaagatccat gaaaacttgg
    13081 aacaattgat tcaagaagtc acaggaatca atgatccgaa aacaatcggg aatatcaagc
    13141 aaaacgtgaa ccgttatgcc aagcaagtcg cttaaaatag gatacgaaaa aggggaatgt
    13201 gacgaaattt ttgtcacatt cccctttttc gaataactag gctgtttgtc cttcaagata
    13261 gggcagatcc aattctttac cgtaacgttg ttctaaagct aggcggatca aacgagctgc
    13321 caggttctca tttcttgcaa ggataggtcc atggaaataa gaaccgaaga catttcggta
    13381 aatgacacct tcagattggt cttcaccatt atttccttga ccttgtacca ctttccccaa
    13441 aggtcgttca ccttcaccta agaaagtccg accattgtgg ttttcaaatc cataataagt
    13501 ttcattgaat tcttcgttat ggataacgat atcaccgata aaccggttat tttcctgact
    13561 taacgtgtag tgatccagtg cactgattcc ttggatcttt tctccattag ctcccatgta
    13621 gtagtgacct agcaattggt agccaccaca aatggctaac atgacgccat cattttcgat
    13681 atagttgatc aaagaatctt tctttttctg gatgtctttt gaaatgatta attgctcaaa
    13741 gtcttgacca ccgccaaaga aaaccaagtc atatttatca gcatcaaaag gttcatgtat
    13801 actaacgatc tccgtatggc aagaaacccc cattttttct gctatatatt tcaacatcaa
    13861 aaggtttccg ttatcaccat atgtgttcat caaatttcca taaaggtggg cgatattgag
    13921 ttcataatta gccacggttc attcctcctt tgataaatcc ttgagcagct agttctttac
    13981 gaagctgcaa tacagcagtg taagtagcta aaatatagac atgctcagtt ggcaattctt
    14041 tgattttttc gattacttct ggtaattctt ttgtttctgt caatttattt tctggaatcc
    14101 cggcaacttt tagacgtaaa gtcatatctg tatgacggtc tcctccagaa ataacagctg
    14161 ggatatccat atcggcaaag ttttcaaaat taccatccca aatccagctg acatcgattc
    14221 cgtctgcgta attggcattt aataaagcca ctaaagaaaa tggataagga gctagaccaa
    14281 tcatatcgat tacttgattg atacctacag gatttttgac aagtactaat gtacattttt
    14341 tcccattgat attgatgact tcttgtcggc cgaatacttt ctcgtcatat cctaaacctt
    14401 gtttgatttt atcaggatcg acattgaagt actctgccac tgcagtagct gctaaagcat
    14461 tgtagacatt atacataccg ccaacttcga ttccgtattc atgaccatcg atcacgaaat
    14521 ctgctgacac attgtccatc cgtaccatat cagttaatcg ataatccaat tcaggacgtt
    14581 tgaagtcaca atttggacag taatatttcc ctaagtttgc ataagtgatc attttataat
    14641 gcaagatgtg atgacaattt ggacataaga caccgtctgt attgtaatga gccatttgtt
    14701 cacgatcttc ttcatggtca aagccataat attttctagg attgactgtt tcgatagaat
    14761 tgaagattgg tgaatcaccg ttactgataa tcgttgcatt tggtgacttt gcggcaccgt
    14821 ctacaatcat tttataggtc gtatagattt ctccataccg atccatttga tcacggaaaa
    14881 tatttgtaaa taagaacagt tctggtttca tatattctgt gactttgctc aaacttgctt
    14941 catctatttc taggacagca aactttttct gtcctttttt tggttttgcc tgcaagaaag
    15001 tcgatacaat tccctgtacc atattcgcac cagtagggtt ggttagaact tcatcgaatt
    15061 gctggcgcaa aatattgact gttaaagcgg tagtcaatgt tttaccgttt gttccggtga
    15121 caacgacgac ttggtagtct tttgccaaac tatctagtat atgtggatcg actttcagcg
    15181 ctagtttacc tggtaaactt gatccgcctt taaaaaaagt ttttaatgcc cattgcgacg
    15241 tttttccaac tgcaatcgca aaatgactgc gtattcccat tatgtaacct ccaaaaacga
    15301 tttgctgacg aataaattca actaatcata ccatatgttg aaaaaaaggt taaattgctt
    15361 ttcttattct taagaaaagg ttacggctga aagtgcatga aatcggacaa aatcgcatga
    15421 tttaacaaaa aaacagcttg aaacaaaatg attgtttcaa gctgctgtga ttttattatt
    15481 ccctcttacc tatattccca ttttaaccga taataatttt ctcgcttgga tattcatagc
    15541 ctagatctcg tgtttctttt ggcacgaata acatcaatgt atatagcatt ccgatccgcc
    15601 caataaacat cagtgtagca atcgtgattt tgcccacaac agacaagtct ccggtaatcc
    15661 ctaaagataa accagttgtt ccaaacgcag aagttacttc gatgatgatc gagatcagcg
    15721 tttgttcttc tgtagcagat aaaaaaacga tacaaaagaa acacatacca agagaaagca
    15781 taaagacaac gactgatttt cgcacatcat cttgatcgat tctccgtcca aaaatattga
    15841 tgttatcttc acttttgagg aaggaatata gatacaaacc gatgattgct acagtagttg
    15901 ttcgaatccc gccgcctaca gaactaggac tgcatccgat aaacatcagt aaagaaaaaa
    15961 tgatcagtgt tgtgatttga aaatcaccca aatcgtgaat ctgcagacca gcattacgag
    16021 tcgtaatcga ataaaacatc gaattgatcc atttgacact catattggaa tcttggaata
    16081 aatggtcctt ttccaataga taaatcaaga cagttcccga aacaaacaag ataacaaaag
    16141 ctaacacagc taatttggta aacaaggaaa aacgaaacgg aagcttcgca ttggaacgtt
    16201 tgtataatag ccattcccgg cactccatca atacaggaaa accaattcct ccgacaaaaa
    16261 tcaaaaacat gatcaggatc aagaaaaaat agtcatgtgc aaagggcttg atggaatccc
    16321 cagtgacgtc aaacccagag ttcgtgacag ccgatatcgc ctgataaaaa ccgtaaaaaa
    16381 cggcatcacg ccaacgatca aaatagcctc tgtaataaaa ataaatagaa aagaatgtcc
    16441 caaaaagtaa ttgaaaccag attaaaatag caaaagtgat ccgaatcagt cggacgatac
    16501 cagacaaacg cggttgattc atatccgtca tgatcagctg tcgctgtttc agtgtgatcc
    16561 gtcgtttaga aaaaatgaca aaagcagtag aaatcatcat gatccccaaa ccaccaactt
    16621 gaaataatat ttccagcagt ataataccgt tatcattgaa cacagaattg atatcaaaag
    16681 tcgatagtcc agtcacactc actgtactga ttgccatgaa cagcatgtcc acaaaagaaa
    16741 catggctatc tggttcgcga aaaatcggca tataaaatag aacgagtgat aagaccgtca
    16801 tcaatatata ataaaaaacg atgatttgga tcgatgagaa atgattggca gcaaacttct
    16861 gtcctcgccg ctgcagcctt cgaaagaata aatcaacatg cacagtacta tcctcctgac
    16921 aatagtcgtt tctaccagta tacaagggga attaggaata ctcaaagaaa ttatcaaaca
    16981 gataacaata cagctttcga ttaaaataga aatggcttat aataaggaaa atcctagaaa
    17041 aaagaaggag gaggaataac aaattgatta atgctcaaca aatcgtagaa aaaatgaaaa
    17101 atcaaaaaat aaattatgat acagttctga aaaaaatgat catgcaatgg gagaaagaag
    17161 aagtaaagcc taagatatta atacatacat gctgtgctcc ttgcagtacg cacacattgg
    17221 aattcatgtc tcaatatgca gagatcacgt tatttttttc aaattcgaat attcatccta
    17281 aaagtgagta tttgcgaaga ttacatgaac aaaaacgatt tgtagaccaa tttaatgaga
    17341 aaactgacca tcatgttgcg ctaatcgttg atgaataccg tccaaatgaa ttcaccaaaa
    17401 tggttttaac aaaccatctt gaaaacgaaa aagaaggtgg tgctcgctgc agtgcatgct
    17461 tcaatatgcg attagatctt gttgcgcaaa aagcgcaaga actaggatac gattactttg
    17521 gaagtgccct gaccatctcg ccaaagaaaa atgcagcttt gatcaatcag atcggaatgg
    17581 atatccaaaa gatttacggg acacaatact tgccaagtga tttcaagaaa aacaaaggct
    17641 atgaacgctc tttgcaaatg tgcaaagagt atgatattta tcgccaatgt tattgtggtt
    17701 gcgtgttcgc tgccaagcag caaggatgcg atctgaaaga aatcaatcgg gaagcaaaag
    17761 cttacttaaa aacatcaacc gtagtttttg aggaaaatta aagaaatctt tcggaaaaac
    17821 gtaagaaaaa aataaagaat ttatggtaga aataaggtag actgtataat ttgtccgtag
    17881 taaagtaagg aaacaagaat aaatttcaat gaaggaagag ataagatgcg aaaagtagca
    17941 cctattttga agccaatcgc tgtattaaca atctcgacga ttgtcgcgac tactacaggt
    18001 attgtgaata gttccagcta ccgtgcacca agttcaagtt ctagtactgt agaagaaaca
    18061 acaccaacta cttcagtctc gacatctgaa ccaacaacaa cggaaagttt gaatgaaacc
    18121 actacgacaa gtacatggga cgatacaaca actagttcgt cgtatgatga gacatataca
    18181 actgacagct caagcgaaac aagtaatacg gtaccagatg gcactccatc ggattcaacc
    18241 aatccaagta caagtccgga tacaagtgct agctccgaaa cgataccaag cagtacgact
    18301 gtagatgata acacgcaaaa tgatgatgca gcacgtacag cacagcaaaa ccaagattca
    18361 ggaaataccc aaacgtataa ccagcaagca ggtgattctc aatgacattt ttactagacc
    18421 ttatcaacgg ggtgcataaa ttccttggct atttagacat cagtcctaaa tatcttaacc
    18481 gtggatatac gattttaagt gtgattccca cgctttattt attgagaatt gtttatggac
    18541 tttggcaaaa ccaaaactat cttcaatttt tcttatatgg acttgcattt ctagtgcttg
    18601 tttattttac tgttttaaat gtattttatt actttttaga taaaaacacg aaagccgatg
    18661 tcactcagct ttttgtgaag tatttacctg atgaagcgtt caacatccag acagaagaat
    18721 cgatagataa tggaaattcg atcgataaag tgaatacaca agaggtcatg gtttcttatg
    18781 acgaagatta tcaattgaaa ttagccgaga atatgcggta tttgattgga aatggtgaga
    18841 tcaaaacaaa tgaactcggt cgcatggatg gatttctggt cgatagaaat acattgtatc
    18901 cttattacta tgtcaagaaa acaggagaga aagagtatgt tctaaatatt ggacgaagct
    18961 actcggacat ggaaaaagta gggaccattc gacttgactc aacagaagac acattggaac
    19021 ctgtcggatt gttcatcgtc ggcggtgatt ttgtcaaaga cgggttacgc tatcatgagc
    19081 cttatcgtct gaaattgatt gcaaaaaagg cacagtcgca ggaagaacca gtggtttata
    19141 gtcgtagcca aagaagaaga cattcataat gtgatgaaac gccgtgtatc agtggttgcg
    19201 ataaaaacgt ttattcggaa taagggggat gtgacacgtc ttttgtcacg ttcctttttt
    19261 atataacgag aaagataaga cgaacacatc acttattctt tcctttcatt tataaacatt
    19321 gtagaataaa gaaagtacaa cgaagtattg tgaaaaaacg taataaataa cgaggaaaat
    19381 acaagtagga ggtaagctgt gaaagaattt ttgaaaaatt gggggatttt gatccttgta
    19441 ttagcggcta ttttattagc tagagtgtac gtgtttacac cagttactgt aaacgggcat
    19501 tcgatggacc ctacattaag tgatggacaa cgattgattt catctaagat ctcaaactat
    19561 gaacgaatgg atattattac tacaaaggaa ccgggggatg aagaacggat gattgttaaa
    19621 cggatcatcg gtatgcctgg agatacagtc aagatggaaa atgaccagtt gaccattaat
    19681 ggcaaaaagt atgatgaacc ttatctggat gagttcaaaa aagaattttc agaagataag
    19741 ttacaaggag aatatgctta tagctcagga ttccaagcac aagcagaaag ttcatccacc
    19801 tttacgagtg actttgaata tactgtgcca aaaggaaagt atcttgttct aggcgataac
    19861 cgcttgattt caaaagacag ccgaatgttt gggttagtcg acaaagatat gatccaagga
    19921 aaagttgttt tccgttattg gcctctttca gaaattaaaa tcatgtgatg aaaaaataaa
    19981 aagaagctgt gacatgtttt ttgtcacagc ttctttttcc gaaaattcct tcttatttct
    20041 tggagttgct cacttttttt gcaatctcat tttaagcttt ttggctgatg gataagaaaa
    20101 gcgaagcgtt tttgttcata aatagctttt ccccacgatg gaaggtatga ctagtagcag
    20161 agacaaagcc cgttttttcc aatcgattat tcaattcttc ttggctaaag ccattatgga
    20221 ctttcggatg actaatttgt tcattcttgt caaagtctac gatgatcaat tgaccgccag
    20281 gagctaaaat ttcataaagt tttgtaagaa tattctccgt atcaggaatg tgtaaaagta
    20341 caagtgatag aaggatgaga ttagcttgga cagcaggaaa ttcgacagaa gcatcagcgt
    20401 ggatcgttcg gacatttttc agatctgctg cttggatctt ttcttctgcc attttcagca
    20461 tagtttctga agcatcggca atgatcagtt ctttgaatct ttccgcaagc ggtaaactaa
    20521 caagcccagt tccgcctccg taatccagca ggactttttg gtggctgtcg cgcggtagat
    20581 aagtagttag ttcttcgcga ataatcttgg ctaatgcttg acggtcaggg gaatcataat
    20641 ggttagcgat ggaatcaaaa atattttttg tcatcaaata gctccttacg taaaactttg
    20701 aaattttaac ttattatagc acgtgaaaag aaagaaagca tgctatactc aattcaaaaa
    20761 gggagaatct agaaagaata tgccgatatc gtttgtaaaa gatagagagg aaaaaggaaa
    20821 gtgtgtccga gaaatattac tagacttgcc tgagtggttt gggcttcctg aatcaacgga
    20881 aaaatatatc gaggaatcaa gtaaactacc tttatggtgt gaaaaaagaa aagaagaata
    20941 tttaggcttt atcactcttt cacagacaag tgaagatact gccgaaatct attctattgt
    21001 atgggaataa aaaaagacta tcatcaccaa ggattaggaa caaaactttt taaagaagca
    21061 gaaggttacg cagcaaaaca ttacaaatat ttgcaagtga agactgtaga cgaggggcac
    21121 tactctatat atgatcaaac tatttgtttc tacgaatcat taggattttc aaggttggaa
    21181 gtttttccaa atttatggga tgaatggaac ccatgtttag ttcttgtcaa aaaattggaa
    21241 caaaagtgag caatagattt aatactaatc tgtgcttgat gaaaattctc actgtaaaaa
    21301 atgctgaaaa tcaagtataa taccatagga acaaactgga aggtgaaaaa gagcatggca
    21361 caactatttt ttaagtatgg cgcaatgaat agcggcaaga cgatcgagat cctaaaagtc
    21421 gcacataatt atgaagaaca aaataagcca gttgtcttaa tgacaagcgg tattgataca
    21481 agagatggtt taggcgttgt ttcaagccga atcggactga aacgtaatgc gatgccgata
    21541 tttgaagaaa cagacgtatt tgacgtaatt cagaaaatgg aaagcaaacc ctattgtgtg
    21601 ctgatcgatg aagcgcaatt cttaaaaaag aaacatgtca ttgcttttac gagaattgtg
    21661 gacgaattgg atattccggt tatggcattt ggtttgaaaa atgattttcg aaacgagtta
    21721 tttgaaggat caaaatattt attgctttat gcagacaaaa tcgaagaaat gaaaacaatc
    21781 tgttggttct gccacaaaaa agcaatcatg aatttacatt atattgatgg aaaccctgtt
    21841 tatgaaggcg atcaagtgca aattggcgga aatgaagctt attaccccgt ttgtcgaaaa
    21901 cattactttc acccatcaat gattacagaa ggagaataag catgtacgat caattacaag
    21961 caattgaaga ccgttatgaa gagcttggag aacttttaag tgacccagaa gtgatttctg
    22021 atacaaagcg ttttatgcag ctttcaaaag aagaagcaaa cacgcgcgaa acagtcgaag
    22081 tttatcgtcg ttataaagaa gtagtacaag gaatcaccga tacagaagaa ctgcttggtg
    22141 aaaaactgga tgatgaaatg gctgaactag caaaagaaga attatctgaa ttaaaaaaag
    22201 aaaaagaagt cttagaagaa aaaatcaaga tcttgctttt accaaaagat ccaaatgacg
    22261 ataaaaatat catcatggaa atccgtggag cagcaggcgg agacgaagca gcattattcg
    22321 ctggcgatct tttcaatatg taccaaaagt atgctgaagc acaaggctgg aaaacagaag
    22381 tgatggaagc taacgttacc ggaatcggtg gatataaaga agtgatcatg atgatcaccg
    22441 gagacaacgt atattcgaaa ttaaaatatg aaagtggtgc gcaccgcgtc cagcgtgttc
    22501 cttcaactga atcgcaaggg cgtatccata cttccaccgc aacagttgtc gtgatgccag
    22561 aagctgaaga agtagagatc gatattgaag acaaagatat ccgtacagat atctatcatg
    22621 cttcaggtgc tggcggacag cacgtcaata aaacagcatc tgctgtacgt ttgactcact
    22681 taccaacagg gatcgttgtt gctatgcaag atgaacgttc tcaaatcaag aaccgtgaaa
    22741 aagcaatgaa aatcttgcgt gctcgtgtgt acgataagat ccagcaagaa gcacaaagcg
    22801 agtatgatgc caatcgaaaa tcagcagtcg gaactgggga tcgttcagaa cggatccgga
    22861 cgtataattt cccgcaaaat cgtgtgactg atcatcgtat cggattaact atccaaaaat
    22921 tagatcagat tttagcaggg aaattagatg agatcgttga tgcattgatc atgtatgatc
    22981 aaacatcaaa actggaagct atgcaaaatg ggtaaaatga cctatcgaga agtcctgtca
    23041 cgggcttctt cttttttaga ggatcatggg aaagaagcat atagtatcca atttttattt
    23101 ttggaacgaa aacaatggaa aaaacttgat tggctccttc atatgaacga agagatttca
    23161 gaagaagaac agcggttgat cgaaaccgat ctgcgacttc tgcttgcaga tcatccacct
    23221 cagtatttgc taggatatgc agatttttat gatcatcggt taaaggtaac tgaagcaaca
    23281 ctgatccctc gaccagaaac agaggagtta gtcgaatggt gtttagacga gacgcctggt
    23341 gtaccgttag aagtgataga tattgggaca gggactggag caattgctat tagtttgaaa
    23401 gcagcaagaa aaaattggca tatatctgct gtggatcttt cagaagaagc attagaagta
    23461 gcgaaagaaa atgctcagaa agaaggaacg aaaatcagtt tttatcatgg agatacatta
    23521 ggaccagtaa tggatcagca atttgatgtg attatttcta atccgccgta catcagtcgg
    23581 aatgaatggg aactgatgga tgaaagtgtc cggtcattcg aacctaaaat ggcccttttt
    23641 gctgagaacg atggattagc tatttatgaa aaaatagcag ttgaagcacc aagcgtacta
    23701 aaatcaaatg gaaagatttt tttagaaatc ggatttcgcc aaggtgaagc agtaaaaaaa
    23761 atatttcagc aagcatttcc agataaaaaa gtggcgataa aaaaggatct ttttggcaat
    23821 gaacgaatga tccaagttta tggttgaagt tgtggatgaa aaatttttta tttgtttttt
    23881 tattataaaa aaacacttat ttgacaagga tgtaaacgac tttttggttt atcaacaagt
    23941 ttatccacta ttgacaaata gattatccac aaacagtgga aaacttgagg ataaactcag
    24001 acaaaataag aatgtatgaa aaaggggttg tggataaact gtggaaacga aacgatatga
    24061 tgaaacagaa ttgcaagagg cagccgaagc actgaaagaa ggagaacttg ttgcttttcc
    24121 taccgaaaca gtatacggat tgggcgccaa cgctctttta ccaaacgctg tcaagaaagt
    24181 gttttctgta aaagggagac cgcaagataa tccattaatc gtccatgtcg cctcttttga
    24241 acaagtaaaa gagtatgtgg acaactttca tccggcagca gagaagattg tgaagaactt
    24301 ctggcctgga ccattaactt tgatatttaa gatcaaaaaa gacactttgc cctcagttgt
    24361 gacgggagga ttatccacag ctgcatttcg tataccggat aacaaaaaaa cactagaagt
    24421 aatcgaactt tccggtgttc cgcttgtcgg tccaagtgca aatacgtcgg gaaaaccaag
    24481 tccaacgact gcagatcatg tatatcatga tctacaagga aaaattaccg ggattattga
    24541 tgatggagct acgcgaattg gtgtagaatc cactgttctt gatttaagtg atccaacagc
    24601 catgcctatg attttacgac caggtgcagt aacgaaagaa caaatcgaag cagtcatcga
    24661 atctcctgtt gctattgatc agcatcttgt aaaagaaaat gaaacaccaa aagcccctgg
    24721 gatgaaatac aaacactact cacccgatac acgtgttctg atggtcagag atggcgattg
    24781 gtcaactgca gttcaatggg caaaaaataa gaagatccgt gcaggtgtca tagcaagccc
    24841 cgaaattgcg gatcaagtgc ggacagatac tgcagctgtt tatatgtata acgacaactc
    24901 agtagaagcg gcggctaaag gattgtttgc aggtctaaga ggattagatg aaccaacact
    24961 tggattagat ttgatttttg tacaagtgta tccagaaact ggattgggga atgcttacat
    25021 gaatcgcttg aaaaaagcag caggacaaaa ttattttgaa aaatgatcaa ttggttattg
    25081 tcgcattctt ttagtatgat acaatgctat caagtaaatc ttctatcagt gaacgaaaaa
    25141 ctaagcgtaa ctaatcgtaa tagaagagat acgaatattt ggcaatttgt ttttgatggg
    25201 aaaaataaaa ttgtaggaaa ataaaattgt aggaaaataa aaaggagctg ttgtttgtgg
    25261 tagattacaa aacgtttgac cctgatcttt gggctgcgat cgccaaagaa gaagaaagac
    25321 aagaacataa tttggagctg attgcctctg aaaactttgt ctccgaagca gtgatggctg
    25381 cacaaggaag tatcttgaca aataaatacg cagaaggtta tccagggcat cgctattatg
    25441 gtgggtgtga atttgtcgat atcgttgaaa atttagcgat tgaccgtgca aaagaattat
    25501 tcggagcgaa atttgcgaac gtccagcctc actccggctc tcaagccaac acggctgctt
    25561 atctcgcttt ggtagaacca ggggacacga tcttaggaat ggatctttcc gcaggcggac
    25621 atctaacaca tggatcacca gtcaacttca gtggcaaaac ctatcacttt gttgcttacg
    25681 gtgttgatcc gacaacagaa gttattgatt ataatgtggt acgtatttta gctagaaaac
    25741 atcaaccaaa attgatcgta gcaggtgcca gtgcttacgg acgaacgatc gactttgcga
    25801 aattcagaga aatcgcagat gaagtaggcg caaaactgat ggtagatatg gcacatatcg
    25861 caggattagt agcagcagga cttcatccta atccagttcc ttatgcagat atcacaacga
    25921 ctaccactca taaaacattg cgtggccctc gaggcggcat gattttgaca aacgatgaag
    25981 cattagcaaa aaaaataaat agtgcggtat ttcctggtat tcaaggcggc cctctagagc
    26041 atgtgattgc gggtaaagca gtagcattca aagaagcatt agatcctgca tttaaagaat
    26101 atagtgaaca aatcatcgcc aatgcaaaag caatggtcaa agttttcaat caagcaattg
    26161 gaaccagagt catttcaggg gcgacagata atcatctgat gttgatcgat gttcgcgagt
    26221 taggtataaa tggaaaagaa gcagagagca ttttggacag tgtgaatatc actgtaaata
    26281 aaaactcgat tccttttgaa acactaagtc cattcaaaac aagcggtatt cgaatcggca
    26341 cgccagcaat cactactcgc gggttcaaag aagaagatgc tgtaaaagtg gctgaactag
    26401 ttgtcaaagc attacaagca aaagatgata acgctcaact agacgaagtc aaaacaggtg
    26461 tacgcgaatt aactgaaaaa tttccgttgc ataaaaaata aaaatttaaa ttccattagt
    26521 aaacagaaaa gttcaatgtt gggcttttct gtttattttt tgggaaaacg gattctttga
    26581 caatatcggt gatgctctct agtatatgag gtgtaatttt agtcttcaca ctaaatctca
    26641 gggaggaaaa gtcatgactg atcgtatctc gttagaaaag gaagcagtag cattcagtga
    26701 tgcaaatgcg cctcatccgc gtatctatga actagcaccg gaagaaggaa gagttttact
    26761 agaagaagta caagaatcac ctgtgaacaa atattccgtc gatattgaag acttgatggt
    26821 ggatactggc gaatggggaa aactcaatat tcgtctcgta cgaccagaag ggaatatgga
    26881 taaattacca gttatttttt atattcatgg agcaggctgg gtttttggca gtgctcaaac
    26941 ccatgataaa ttgatcagag aacttgcggt tcgtacgaat tccgtcgttg tctttccaga
    27001 atatagtcga tcaccagaag caaaatatcc aacagcaatt gaacaaaatt atgctgtgtt
    27061 gcaacagctg aataaattag ccaagtcaaa aaatctggat ctcgagaatc taatcgttgc
    27121 aggagattca gtaggtggta acatggctac agtcatgacg atcttaacaa aagaacgaaa
    27181 gggcctccca atatccaagc aattgctgta ttatccagtc acaaacgctg attttgatac
    27241 agattcctat catgaattcg gagaaaacta ttttttgaca agagaaggaa tgatgtggtt
    27301 ttgggaccaa tatacgacga atgaagaaga gcgtgctgaa atcacagctt cgcctttgag
    27361 agcaaatata aatgaactaa atgatcttcc ttcagcaatg attttaacgg gagaagcgga
    27421 tgtattaaga gatgaaggtg aggcttatgc gcgcaaactt cgtgatgcag gggttcctgt
    27481 tacacaagta cgcttccaag gaatcatcca tgattttgtc atggtaaatg ctatggatca
    27541 gacaaaggca acgcgtgcag caatggcatt atctacttct tggatcaaga aaaaagaata
    27601 agctttgctt gtccgcagga aaacttcttt tcaaaaacgg attttcttag gaaaaatggc
    27661 gagtttgact agtcaatcac ttgattttgt tttacaatta aaaagaaacg acagaacaaa
    27721 ggagagctta aaaaatgggc aaatttcaag tgatcgatca tccattgatt caacacaaac
    27781 taactattat tcgggacaaa aactgcggaa caaaggtttt tcgtgaagta gtcgatgaaa
    27841 tcgctatgtt gatggcatat gaagtatcac gggatatgcc attggaagac atcgtgatcg
    27901 aaacaccgat cactgaaaca acacaaaaaa cgttgtctgg taaaaaagta gcgattattc
    27961 caatcttgcg cgcaggtatt ggaatggttg acggtatctt ggaattgatt ccagctgcta
    28021 aagtgggaca tatcggtctt tatcgagatg aagaaacatt ggaaccacat gaatatttcg
    28081 tcaaacttcc agaagacatt gatgcacgtc agttgtttgt agtagatcca atgttggcaa
    28141 caggcggatc agcaatcatg gcaatcgatg cattgaaaga acgtggcgcg tcgaacatta
    28201 aatttgtttg tttggtagca gcacctgagg gagtaaaagc tttgcaagaa gcgcatcctg
    28261 atattgacat ctatacagct tctctagatg aaaaattgaa tgaacatggt tatatcgttc
    28321 ctggactagg ggatgcgggt gaccgtttgt ttggtacaaa ataagtaaat acgaaaaagg
    28381 gtgtgacaca acttttgtca catccttttt tggtcatttt taacgtttga tgcagaacag
    28441 ctttttcaca gctttcgttt gcatataaaa aaaccatccc aaaaatgcag agatggtcaa
    28501 attcaaatct tttttagttc tttgtagtta acgattacta cacccttact ttgcgtcatc
    28561 aagttcgcat tttctgcagt ttcatcaatc tcaacaacag cggaattttt caattgcttt
    28621 gaaatcgttc cagtttgcga cttgccgtga attgtgaaca ttacgtgagt attgatcttg
    28681 aatttttcac caatttccga tggtacgata gttgtatcaa attttccaaa agttgccatt
    28741 ttcataaaac ctgcctttca catcaattat accacgtttt atgaaaaata tcatgaaatt
    28801 aaactaattt tccatcggac tctttacaat cagccaaata gagtatataa tttcttttgg
    28861 ataaggccag cttagctcag ttggtagagc aacgcactcg taacgcgtag gtcgtaggtt
    28921 cgatccctat agctggcatt aaaagagaag acagatatat caaggatttt taatccattg
    28981 atacatctgt ctttttgttt aaaggaaata aagtatgctt tcttagcaat agagcatgta
    29041 ttatttctat aaaaatttag gagaataaaa cgactagcaa tatagctgtg aaatcaaata
    29101 tcacatgaac tgcccaactt gtaatgatcg agttgctttt aatggcagct tggttgaata
    29161 acaatcttgc caccccttgt atcaaaagga tgtgtgctac agtgtgtaaa atatttccat
    29221 tatcataagt actgtaatgg ataaatccaa agatgattgc tgacaagaaa ctagcgacag
    29281 gaatgctgaa cttactagaa aaaatagcga gaaaatacac tgagaacaat tcttctccaa
    29341 gtatcatgat aggcaaaata ataaataata acgggctgaa agcctcattt attggattgc
    29401 ctgttaaacc ccatttcaaa atttgttgca aaaataccga gactgcggca ctgattacta
    29461 cattgataaa aaaatatttg gctatatttt tgacaggagc gacaggtttc gagaacattt
    29521 ttttcgtatc ttttttacca aaaacaagtg taaatgctat aaatccagtg atagttaaag
    29581 aaaaaatgct aataatggat ggcgcaaata gcaaccctaa caaaccgagt acaacgacaa
    29641 tagtgcccaa tatccctttt ttaagttcta ttttttttcc taaaatgtta ttcatgataa
    29701 taactcctac tattcagttt ttgaagatag agtcagtata catgaagagt taaaataggc
    29761 aatgtttttt tatggatatt tgtattgcta aaaatttatc ttatatattc attttgatta
    29821 tactactttt atttgtaaaa attttctagc aaaaccaagt gcttgcaact gattaagcgt
    29881 acaatttttt agatgttccg agcgtacttc aatcatttca aaggagttgc tacttaaatc
    29941 gatatttttt aaatcagtat caaaaaagct agcattttct aaatcattag tagaaaacat
    30001 tattttagtg agggaacagt ctacaaaatc tgcgcttgat aagacagagt gctcaaaggt
    30061 actttctttt atgtttgaac cagataaatt tacatagtcc attttacaat tctcgaataa
    30121 cgtgttccca atataacttt ccatcaattt agtacctgtt aatttacaat tgacaaattt
    30181 cacgcgatgc aacatgcttt ttgtcaatat acagcctgaa aaatcacagt tttcgaatat
    30241 acagtcggta atctccattc tttgaaaatc attggaagca aaaaatgcat acttgaaaat
    30301 agatttgtaa ataattggat ggcagattat ttggttttcg atgacctctt tttgtgaaag
    30361 gatattatac agttcaaaat cttcgttttc atagatatga aaaaaggatc ctttattcaa
    30421 gcttgcttca ttaactttag gaaaaatcat atttaattac ctccattttc ataaagtcat
    30481 attaacaaaa gctaaaccaa cttacattag cagaaaatga gataggtttt cgcctttttc
    30541 gataacgata gtgtcgctat ctcttgaaac gttcttagaa ttgccctgag agacacaaat
    30601 taggcgtaat tctaataaaa atcttagaat aaaaattttt actgatttaa tttagaatgt
    30661 ttttaaaata aaaatcgttg ccataacagt gtattgaaag gttttaacaa tccagtaatg
    30721 atttaaaaaa atctagatgt agcgtatact ttgtttatag aatgtagtgg gaagaaatat
    30781 atttttggga ggaaatcgtg atgtctaaaa gtgaagaaat agaaaacatg gtactaaaat
    30841 tatatgatct cgttttaaat ccagagatca aagaaaagga acgtatactt ttgatagacg
    30901 caaagacagg cttagaaaaa ggtcagtatt atcctaaagt cataaataat ttggaacgta
    30961 gtttacgtcc gttagcaatc aggggagaat tgtctaaacc agtatcaccg ttttatatgg
    31021 agatatcaac aataggaaaa tttgaaaaag aattaggtcg aggaatggct tcggcaccga
    31081 ttacttttgg gcatttataa aaacgagtta ttcatctcaa tgaattaaaa agtatagtca
    31141 atctcataat gcaggctagg ttcatttatt tgaacagagt ctgtattttt ttattctaaa
    31201 taaagaaaca gatgtttctt tatattgtat tttatccttt aattaacaca aaaacagcta
    31261 gtataaacta ataatgttaa ttaaaagtgt
//
LOCUS       DAFLVO010000030        29957 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.030, whole genome shotgun sequence.
ACCESSION   DAFLVO010000030 DAFLVO010000000
VERSION     DAFLVO010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29957
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.030"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..616
                     /locus_tag="L1U99_001401"
     CDS             <1..616
                     /locus_tag="L1U99_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBN1211949.1"
                     /translation="FVFAPLEGEDLASFLVGAAIMMIGMTLFLFGADYSMMEVGDLVG
                     KYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQQVYDISDGEIGRVLLIGIVSVGT
                     GVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFTSSEFMPIAFDSGGVTTGPVTVPF
                     ILALAGGMTSMIKQKKNENDSFGMVGIASLGPILAVMILGVIFQ"
     gene            613..1386
                     /locus_tag="L1U99_001402"
     CDS             613..1386
                     /locus_tag="L1U99_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBN1211950.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            1383..1781
                     /locus_tag="L1U99_001403"
     CDS             1383..1781
                     /locus_tag="L1U99_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HBN1211951.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            1966..2637
                     /locus_tag="L1U99_001404"
     CDS             1966..2637
                     /locus_tag="L1U99_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211952.1"
                     /translation="MNFLVVLKDTLIERFTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            2696..3136
                     /locus_tag="L1U99_001405"
     CDS             2696..3136
                     /locus_tag="L1U99_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1211953.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            3148..3816
                     /locus_tag="L1U99_001406"
     CDS             3148..3816
                     /locus_tag="L1U99_001406"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBN1211954.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            3880..4503
                     /locus_tag="L1U99_001407"
     CDS             3880..4503
                     /locus_tag="L1U99_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBN1211955.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            4559..4945
                     /locus_tag="L1U99_001408"
     CDS             4559..4945
                     /locus_tag="L1U99_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HBN1211956.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            5158..6549
                     /locus_tag="L1U99_001409"
     CDS             5158..6549
                     /locus_tag="L1U99_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HBN1211957.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            7160..7528
                     /locus_tag="L1U99_001410"
     CDS             7160..7528
                     /locus_tag="L1U99_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HBN1211958.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            7708..8649
                     /locus_tag="L1U99_001411"
     CDS             7708..8649
                     /locus_tag="L1U99_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HBN1211959.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            8718..9449
                     /locus_tag="L1U99_001412"
     CDS             8718..9449
                     /locus_tag="L1U99_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBN1211960.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            9593..11773
                     /locus_tag="L1U99_001413"
     CDS             9593..11773
                     /locus_tag="L1U99_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBN1211961.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            11793..12275
                     /locus_tag="L1U99_001414"
     CDS             11793..12275
                     /locus_tag="L1U99_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HBN1211962.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            12291..13052
                     /locus_tag="L1U99_001415"
     CDS             12291..13052
                     /locus_tag="L1U99_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBN1211963.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            13183..14517
                     /locus_tag="L1U99_001416"
     CDS             13183..14517
                     /locus_tag="L1U99_001416"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBN1211964.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            14824..15309
                     /locus_tag="L1U99_001417"
     CDS             14824..15309
                     /locus_tag="L1U99_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HBN1211965.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            15302..15985
                     /locus_tag="L1U99_001418"
     CDS             15302..15985
                     /locus_tag="L1U99_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBN1211966.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            16111..18756
                     /gene="polA"
                     /locus_tag="L1U99_001419"
     CDS             16111..18756
                     /gene="polA"
                     /locus_tag="L1U99_001419"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBN1211967.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            18801..19637
                     /gene="mutM"
                     /locus_tag="L1U99_001420"
     CDS             18801..19637
                     /gene="mutM"
                     /locus_tag="L1U99_001420"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HBN1211968.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            19601..20230
                     /locus_tag="L1U99_001421"
     CDS             19601..20230
                     /locus_tag="L1U99_001421"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBN1211969.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            20282..20614
                     /locus_tag="L1U99_001422"
     CDS             20282..20614
                     /locus_tag="L1U99_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBN1211970.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            20926..21417
                     /gene="nrdR"
                     /locus_tag="L1U99_001423"
     CDS             20926..21417
                     /gene="nrdR"
                     /locus_tag="L1U99_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBN1211971.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            21440..22813
                     /locus_tag="L1U99_001424"
     CDS             21440..22813
                     /locus_tag="L1U99_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBN1211972.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            22813..23739
                     /gene="dnaI"
                     /locus_tag="L1U99_001425"
     CDS             22813..23739
                     /gene="dnaI"
                     /locus_tag="L1U99_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HBN1211973.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            23868..24308
                     /locus_tag="L1U99_001426"
     CDS             23868..24308
                     /locus_tag="L1U99_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBN1211974.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            24452..25153
                     /locus_tag="L1U99_001427"
     CDS             24452..25153
                     /locus_tag="L1U99_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HBN1211975.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            25150..26271
                     /locus_tag="L1U99_001428"
     CDS             25150..26271
                     /locus_tag="L1U99_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBN1211976.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            26286..27518
                     /gene="pepT"
                     /locus_tag="L1U99_001429"
     CDS             26286..27518
                     /gene="pepT"
                     /locus_tag="L1U99_001429"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBN1211977.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            27650..28558
                     /locus_tag="L1U99_001430"
     CDS             27650..28558
                     /locus_tag="L1U99_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBN1211978.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            28593..28865
                     /locus_tag="L1U99_001431"
     CDS             28593..28865
                     /locus_tag="L1U99_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBN1211979.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            28876..29922
                     /locus_tag="L1U99_001432"
     CDS             28876..29922
                     /locus_tag="L1U99_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBN1211980.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
BASE COUNT         9966 a         5142 c         6584 g         8265 t
ORIGIN      
        1 gtttgttttt gcaccgttag aaggagaaga cctcgcttca tttctggttg gtgcggcaat
       61 catgatgatc ggaatgacgc tctttttgtt tggagcagat tattctatga tggaagtcgg
      121 agatctagta gggaaatata tgatcaaaaa gaaaagtttg accgttttgg tcagtttggg
      181 atttgctatc gggatcgtga tcacgattgc tgaaccttcc gtgcaagttt tgggacaaca
      241 agtatatgat atatctgacg gagagattgg cagagtgttg ctgattggga tcgtcagcgt
      301 cggcactgga gtatttctag cctttgcgct gcttcgggtc gtattcaagc tatcctatta
      361 tcaattgatg gctataggct acataggcgt tttgatcgcc tcatttttca ccagttccga
      421 atttatgccg attgcttttg attcgggggg agtgactact ggtccagtaa ctgttccatt
      481 tatcttggcc cttgccggag ggatgactag tatgatcaaa caaaagaaaa atgaaaatga
      541 cagttttgga atggtcggta ttgcttcgtt agggccgatt cttgccgtga tgattttggg
      601 ggtgatcttc caatgagttt ctggcagcaa gtgatagatg gaatcgaaat cgttaccatg
      661 gaagtcattt tggcagtggc acctatcgta atcctatttg ttttaatgaa tatcattagt
      721 tttcgtatgc gcaaaaagcg tttctttgac attatgaaag gtttcttgat aacgactatt
      781 gggttgatcc ttttcctgca cggagtcaat atggcttatg taccggtagg acagcattta
      841 ggcagtgcta ttgcgggatt gccttacaat tatatactgg ttccccttgg ctttttaatg
      901 gggttcttag tagggtttgc tgagccggcg attcatgtaa tgatcaaaca ggttgaagaa
      961 ttgagcgagg ggagaatccg atcgaaaatc atgctgatgg taatttcaat tgggatcggc
     1021 gcagcagtag gattgtctat gtggcgtttg ctcgtcggat tctctcttta ttatttcttg
     1081 atcccaggat acgggctagc atttatttta ggacgaaaag tggacaagat ctttttagca
     1141 atggcttttg ataacggtgg agtagcaacg ggcccgatgt gttcgacatt tattttatca
     1201 atgagcgtgg caatcgctgc acaaattgaa ggaagagatc cgatcattga cgggtttggt
     1261 gtggttgcaa tgattgcatt gacaccaata ttatccactt tagtactagg atatatttat
     1321 aaacgaaaag atgaaaaaga cagaatcgaa aaagaaagat tgcaaaaatt gggggaaagc
     1381 aaatgaaaga tcttgtagca ttgaatcttc acatgattgt gacgatcgtt gacggaggaa
     1441 tgggcgaaga tgttatcgac ttttcaaaag aagcaggtgc agcaggcgga acgatcttac
     1501 atggaagagg ttctggtgta catgattcag ggaaattttt aggtttggac atttcgccag
     1561 aaaaagatat tgtgttgaca ttagtacccg atagtttgac gaataaagta atggatgcga
     1621 ttggtcaagg catcaacatc gatattccag gtaatggtat ttgttttagt attgatgtag
     1681 acaaagtcat tggtatcact aagattcatc aatatcgaga aattatcgga atgcaagaac
     1741 ttttagatga aaataacgat agagaaaagt ctgaatcata gacaagcgtt tgaagaggaa
     1801 ataaacacaa acaagaaggc ggatgagcgt tatttccgct tttttgtttg tatttttctc
     1861 gtgaatactt atgaaatagt aaatttttat gaaattctac tctaagcatc agactttctt
     1921 ttcaaaatat gctattttaa aaatgatgaa aaaaggggga gaaaaatgaa ttttttagtt
     1981 gttttaaaag atactctgat tgagcgattt acatttctat atgttcaatt gcaggaaaat
     2041 aaaacattgc tgcatttttc accagagttc catctagagg ggctaacatt aggagaaatc
     2101 tatcaagcag aagggctgtc ggctgttttg cactttttta aggtagaatt ggaattacca
     2161 gtaaaagatt atatcgagct ttctcttgaa tcttgggatc gagcagtggt tgaactgttt
     2221 ccagaaggtt taatgatcga tacaaacgat gggaagatcc atctgactgc agcagaactg
     2281 caaaaacaaa tgcgttatca aatagatgac gaaaattctt tttctatttt tagacgtcag
     2341 caaaagattc taaaaagctt tttaaaagtg atcagtaaaa aacggaatct gatcaaaacg
     2401 acacagctgt tgaaaaaata tccaggtctg cttcacacgt ctattcaatt tcctcaattg
     2461 attacgatga tccatcgttt tatacgtatg caacagctac catctaagaa gctgtttctt
     2521 ccattgacgg acacatttcg agtagtcaac agagaagata aaaagaaagt gattgtgatt
     2581 gactttacca gaaatcggaa tgtccttcac caagttgcaa tggaaaaggc caattaaggc
     2641 tttttctttt tggatttttt tgtcataata aatattagat gatggaggag ataatatgat
     2701 gcaaacatgg ttagaaaggc taatacgatt tcagcagaac tatcacaaac ttatgcaggg
     2761 aagatatgcg aaatttgatc agttgaatcg cggtctattg atcgctgcgc ttgtctttag
     2821 tttgctaagt cgttggttgc cctatagaat cggacaattg ttgttcatcg tctttttcgg
     2881 atggatgata tttcgtttcc tatcaaaaaa aatctacccc agactaaatg agaatcaacg
     2941 ttatttgaaa tatcttgata gagtcaaaga aaaatatcat cagataaaaa acaaaaagca
     3001 agtcaaaatg gatcgaaaaa gttatacttt ttttgagtgc ccgaattgtc atcaaaagca
     3061 gcgtgcacct aaaggaaaag gacgaatacg tgtgacatgc aaaacatgtg gtataaaatt
     3121 cgaaacgaat gtttaaggga gaaaagaatg aaattagtat tattacgtca tggcgaaagc
     3181 gaagcaaatt ttgaaaatta ctggacagga tggctagatg tcgccttaac agaaaaagga
     3241 aaagaacaag cagcagttgc cggtcaaaaa atgcttgaag ccggacttca attcgatgcc
     3301 gtttatacct ctgttttgaa acgtgcgatt cttaccggac aagtcgcact agaagaaatg
     3361 ggtcagttat ggcttcctat aataaaaaca tggcgtctaa atgaacggca ttatggggat
     3421 cttgtgggta aaaacaaaga taagatgaaa gaaatatacg gaaaagatca agtaaaaaca
     3481 tggcgcagag gatatacgga agttccgccg ttaaccgcag aaaatagatt tgaccgcaga
     3541 tatgatcact tggatccgca tttgatccca tacggagaaa gtctggaaat gacagtgaat
     3601 cggatcattc ccttatggca agatcatcta gcaccaaaac taaaagatcg gcaagattta
     3661 ctagttgtgg gtcatggtaa tagcatccga gcactgacaa aatatttaga agatgttcct
     3721 gaagatcaaa tggatacgat cgatatccca aatgcacaac caatccagta tacattagca
     3781 gatgatttga caattctgga caaaaaaata ctttaaagaa cacctttatc taaaagtgag
     3841 agatagaaaa aagaagcaaa ggaatggaac aaaaggaaca tgaaaaatta tatatgggac
     3901 tttgatggta cattgtttga tacgtatccc gcaatggtag atggtgcatg gcaagcacta
     3961 aaagattttg gtatcagtat ggacaaaaaa gaaatctact tcaaaatgaa aaagtattct
     4021 actagttatt tgatcaatga atcaaacttg aatgccagag agtttaatga attatttcac
     4081 cgatatgaaa aagaaagtac ggaagtttcc cgtccatttc cagaaacgaa acaagtactg
     4141 gaaatgctaa aagacaacgg cggtcgtcat ttcatcctga cccaccgttt gacagaatca
     4201 acatggggcc tgttaaaaga acatcgattg gcacatctga ttgaggaagt agtagggatc
     4261 gatcaggact ttcctcgtaa acctgatcca gcatctttaa attatttgat cgatactttt
     4321 catttagaaa gaacagacac gatgatgatc ggcgatcgtc gtttagatat cgaagcaggg
     4381 aaaaatgcag gagtcgctac ttgtctttac gacatcgatc attttctggg tgagatcccg
     4441 gcagattatg tggtaggaaa tctgaatgaa atccttacct tgcagagcat cattaaaaag
     4501 tagtatcccc tttcaaagga gatatgttat aattttcata aaggagtgat aaaattatat
     4561 ggaaatcaga agacaaaaag aagttgtaga agcatttcat tatgatatga gattgccgaa
     4621 ccaagaagta gaaacagatt tgaaagtagg cttctcgcct ttaaaagaaa cgatcgaaaa
     4681 ctatccgaaa gaacatagca tcgtaggagc acgcttagag ttccgtttag tgtttgatac
     4741 atatgtttta tctggaagtg tgagtcagat caatcatatc ctcaatcgga aaattgaagg
     4801 tcaaaatgat gtcacacaag aagaagtgga cgagctagta gcaccgttat tcgatatcgt
     4861 acgccgaatg tcttatgagg tgacagagat cgccttagat cagcctgggg taaaattgaa
     4921 ttttcaatca gaaaaacaag aatagacagt aaaaacatac ctgcgataga ttaaagctat
     4981 cacaggtatg tttttttatt actaattgta agcaaaaaga atgtcatttc gataaaaatc
     5041 gtctaaaata taaaagtcac tgaaaaaaat tttttcagga ggatggttga agaatcattc
     5101 tcgggaacct ttacttcctt cgatggactt gtcattaata atatgaggag gagaaaaatg
     5161 acaacactca tcacagtttt agtggttcta gtttttgcgg cattattata tgtgttctat
     5221 cgtatgcaaa agcgccatac aaaattttca acacgcgtct ttacagcatt aggagttggt
     5281 atcgtctttg gcggtctgct tcaattgatc tttggtgtag acgacaaagt cgttactcaa
     5341 tcaatggaat ggatcgggat tgtaggtcaa ggatatgtat cattcttgca aatgctagtt
     5401 atgcctttag tgtttatttc gatcattggt gcattcacaa aaatgaaagt ttctgaaaag
     5461 ctagggaaaa ttagtgcgac tgtattgact tctttacttg gaacaacagc tattgcagca
     5521 ttgatcggaa ttggttcaac aatgctgttc ggactccaag gagctaaatt cacacaagga
     5581 gctgcagaaa cagcacgaat ctctgaactg gcaacacgtc aggaaacagt tgaaaactta
     5641 tcgattccac agcagatttt atcctttatc cctaaaaacg tttttgctga tttagcaggt
     5701 agtcgtgcaa caagtacgat tggagtcgtt attttcgcgg catttgtcgg aatcgcttat
     5761 ctaggcgtga aaagaaaagc gccaaaagaa gcagcattct tttcagattt agtcgacagt
     5821 ctgtataaaa tcattatgcg gatcgtgacg cttgttttgc gtttgacacc ttatggagta
     5881 tttgctttga tgacaaacgt tttggcaaca agtgattttg cagctatcgt caatttaggt
     5941 aaatttgtcg ttgcttctta cgtagcattg cttgctgttt tgattgtcca ctcactgatt
     6001 ttgattggtg caaaagtcaa tccaatcaac tatttcaaaa aagcctttcc ggtattgagc
     6061 tttgcgttta cttcacgttc aagtgctgga gctttgccat tgaatatcga gactcagaca
     6121 aaagctttag gagtagatga tgcaacagct aatttctcag caagttttgg tttgtctatt
     6181 ggacaaaacg gctgtgctgg cgtttatcca gctatgttgg caacgatcgt cgcaccagca
     6241 gctggagtga atgtctttag tttggaattt attttgatgc ttgtggcaat tgtaacaatc
     6301 agttcttttg gtgtagctgg agtcggtggg ggcgcaacat ttgcttcact gatcgtttta
     6361 ggggcaatga acttgccagt agcaatcgtt gggttagtta tctctgttga accattaatc
     6421 gatatggcac gtacagcagt aaacgtcagc ggtagcatgg tagctggtat cgtgacaagt
     6481 gcacgcatca aagatttaga tcgcgatgtc atcaatgatg attctaaagt gatcgatgtg
     6541 aatgcatagt caaaaagagg ttgtgataga agtggtcagc tttaagaaat aagaagaagt
     6601 ttcctaaaaa tagtttctca aatttttgtg aaatttcggc ttatttccga gaagctactt
     6661 ctgaaacacc gtgaataaga ggttgtgaaa aagctgccct gcatcaagta ataagaacag
     6721 ccaaacaaaa atagttcctc atattttacg tttggttgag cttattaccg cagatgcaag
     6781 cttttgaaca ccgtttaaga aagaggtcgt gagcctgccg tttcactctg agtcacaaag
     6841 agcaatttca aaaaatagct tctcatgttt gttgaatatt gtgtcttgtg accgaggagt
     6901 tgtcaggaga acaccgttta ccagaggttg tgacttgttt ttagtcacga cctctttttt
     6961 tatttattcc atataaatac acattattta ttccgaaaag tgaaagcgca aataacaaaa
     7021 acaaccaact tatttattat taaagaaaag cgtatttaag taggacgatt ctgttgagag
     7081 ctttcgtaga ttttcccatt ttcctatggt aaactgacaa agttgagaat gttagaacag
     7141 atcgtttagg aggaaacaga tgtttacgaa tgaaataaaa atcatgcttt atgtggacga
     7201 tgtagaaaaa aatgcaacgt tttggagagc agttggcttt gcggaaaaag atcgtcaaga
     7261 aatggatggg acgcttataa ttgaagtagg agttgaggac agtcaaacct catttctgtt
     7321 atatgatcga gcatttgttg agtcccattc acctggcaca gctactagtg ccccatcttt
     7381 gatgttttac agtaaagata tctttggact atataaaaaa atgcagacgc aatcagtcac
     7441 attaggtgat atggtacagc ttggagaaga atatgtcttt aactttgctg atcccgatgg
     7501 caactacttt gcggttacag gtaaataata gaaataaaga ctttgttttt ctgtgcgaaa
     7561 caggaaagcg aagtcttttt aattcaaata ataatattat gtaaacaaaa aactttccat
     7621 gcgtaattat acacaagcaa ataaatcgtc aaatgcgaac gccttcttta tactgtttag
     7681 gaacgaaaag aaggaaggaa gaaatacatg gattatcaag tactgcttta ttacaattat
     7741 acaaaaatcg aagaaccaga ggaatttgcc aaaaatcatt tagccttttg caaatctttg
     7801 gatcttaaag gtcgtattct agtagctgaa gaaggaataa atggtactgt gtctggaacc
     7861 gttgaaaaca cgactgccta tatgaaagca atgaaagctg atcctcgatt tgctgatacg
     7921 atgttcaaga tcgatccaag cgaaggacat gcctttaaga agatgtttgt aagataccgt
     7981 ccagagcttg taagtttaaa gctagaagag gacattgatc caaaccaagt gacaggtgcc
     8041 tatctttcac cgcaagaatt taaagaagct attttagatg aacagacagt ggtgattgat
     8101 gcacggaatg attatgaata tgacttggga cattttcgag gggctgtacg cccagatata
     8161 cgcagttttc gagagcttcc agactggatc cgcgagcaca aagaagaatt tatggaaaaa
     8221 cgggtagtga cctactgtac tggtggcatt cgttgcgaga agttttctgg ttggcttgtc
     8281 cgtgaaggat tcaaagatgt cggacagctg catggcggta ttgctactta tggtaaggat
     8341 cctgaagtcc aaggagaatt atgggacggc aagatgtatg tgtttgatga acggatcgct
     8401 gtcgatatca accaagtaga taaacaaatc gtcggtcgcg actggtttga cggaacacca
     8461 tgtgaacgat atatcaattg tagcaatcct gagtgcaatc gtcagattct tgcttccatt
     8521 gaaaatgaag aaaaacattt aggagcatgt agcatagagt gtgcgaaaca tccgcgcaat
     8581 cgctatgttc aagaccatgg aatctctcca gaagaagcag aactgcggtt tacagcttta
     8641 attaaataga aaacaatagt tttgattgtc gaccatttcc aatatgcgct atactagcgt
     8701 tgaggatggt gatccacatg aaatcattga tttatgctat tggggatgtc catggcaaac
     8761 atgagctttt tgaaaaactt attcactatt atgatccaaa gatccatcag cttgttttat
     8821 taggggatct caatgatcga ggtcctcgta caaaagaatg ttttttatta ggaaagcaat
     8881 tagtcgaaga aacaggagcc atttacctcc ggggaaacca tgaagaatat tttttgcaat
     8941 ttctgcaatc accggaggac tggtatgcgc cttatatgag aaatggtgga aaagaaacgt
     9001 ttgaaagcct gattcaccca ggggcatcgg aggaatactc cccaactgaa atctcgatga
     9061 tgatccaatc gagatattca gaactgatta aatttttagt ccagcgcccc ttgtattatg
     9121 aatgggaaaa ttatcttttt gtccatgccg gtgtggattt gacaaagaaa gactggcgta
     9181 agacaagtct aagagacttt atttggataa gggaaccatt tcatgaaggg aaaaacaata
     9241 caggtaagac aattgtattt ggacatacga ttacaccaat gctccatgga gatatgcaga
     9301 caacagacct ctggattcag gatcataaaa tcggaatgga cggtggggct gtattcggag
     9361 ggtcattgca tggggttgtt tttgacaagg aaggtattct tcaagatatt gaatatcaga
     9421 acaacgaagg accttggcat ggaatctgac taatggaaag aatgaaggag ctgtgacttt
     9481 gttgcggctc tttttatttt tatagagaat attgtttctt tcagtagttt aacccaggat
     9541 aaaaagtatg atagaataaa gaagcaattt ttagcagaaa agaggcattt taatgacgga
     9601 aaatttgaac cagacgatca ttcagcttgt acaaaaagaa ctttcagact atcgtcctaa
     9661 gcagttgact actgtactta atttgttaaa tgaaggaaac actgttcctt ttatcgcgcg
     9721 ttaccgaaaa gaaatgactg gaagtcttga tgaagtccag attcgtgaaa tcgaagagcg
     9781 gtatgcctat cttgaaaact tagaaaaacg taaaactgaa gtgattcggc taatcgatga
     9841 acaagggaaa ctgactcccg agttagaagc agaaatcacc caagccgtga aaatgcaaca
     9901 agtggaagat ttgtatcgtc catacaaaca aaaacgacgg acaaaagcaa cgattgctaa
     9961 agaaaaagga cttgaaccac tcgcgaagtg gctgatgcag cttacagatg gagaggtgca
    10021 atctgaagca gaaaaatata ttgacaaaga aaaagaagtc tcttctgccg aagaagcgtt
    10081 gcacggtgct catgagatta ttgctgaaca agtcagcgat aatgcaaaat ttcggacttg
    10141 gattcggtct tatacgtata acaaaggtat gtatgtcagc aatgtcaagg atgagcaagc
    10201 agatgaaaaa ggcgtatatg aaatgtatta tgactttgca gaacccgtcc ataaaatggt
    10261 ttctcatcga atattagcta ctaatcgtgg agaaaaagaa gatattctga aagtattctt
    10321 tcaagtagat gaagcagcaa ttttagctta cttggatcgc caaatagtca aaaatcctgc
    10381 ctctccttct tcttcattcg tcagagaagc ctatcaggat agttataaac gctttattca
    10441 gccagcaatc gagcgagaac tgcgcaatga attgactgaa aaggcagatg agcaagcaat
    10501 cgctattttc ggcgaaaacc tccgtaatct tttgttgcaa ccgccactaa aaggtaaagt
    10561 tgtcctggga tttgatccgg cttatcgtac tggatgtaaa ctagcagtcg tagatgcgac
    10621 agggaaagtt ttagcaatcg aagttattta tcctcataaa cctgcagcgc aagcaaaaag
    10681 agaagctgct ggaccagctt ttatccaatt aattaataaa tatcaagtag atatggtagc
    10741 tatcggaaat ggtacagcca gtcgggaatc tgaacttttt gtggctgagc agttgaaatc
    10801 cgccgaccat aaaacctatt acgctatcgt caacgaagca ggcgcttctg tttactccgc
    10861 tagcgaaatt gcacgaaaag aatttccgca tctacaagtt gaagaaagaa gtgctgtttc
    10921 tattgcccgt cgcctgcaag atcctttagc tgaattagtc aaaatcgatc ctaaagctgt
    10981 cggagtaggc cagtaccaac atgacgtttc tcaaaaacgt ttggctgaac aattggattt
    11041 tgttgtggaa acagcggtta accaagtagg tgtggatgtg aatacagcaa gcccgcagct
    11101 cttgcagcat atatcaggat tgaataaaac aactgcccaa aacattgtca tttatcgtga
    11161 agaaaacgga gaattcaccg cacgaactca attgaaaaaa gtgccacgct taggaccaaa
    11221 agcatatgaa caagcaatcg gattcttgcg agtccctggt gggaaaaaca ttttggacaa
    11281 cacaggtatc catcccgaaa gttattctat tgcaaaagaa atattaactt cagtccaact
    11341 ttcagaaaaa gagcttggta cagaagaagc agtagaaaaa ttgacacgat tatccgtaga
    11401 gaaactggct gaaagcctat cagtcggaga agaaacgtta gccgatattt tagctgggct
    11461 gacacaacct ggacgagata tgcgtgatga gatgccagcg cccttattac gtacagatgt
    11521 attgagtatg gaagacttga aaccagggat ggaattgact ggaacggtcc gtaatgtcat
    11581 tgacttcggc gcatttgttg atatcggtgt gaagcaagac ggacttgtcc atatatcgaa
    11641 actcagcaaa aaattcgtca agcatcctac agatgtcgtg tcagtaggag atatcgtaac
    11701 agtttggata gaacaagtcg atacgaaaaa aggcagaatc agtttgacga tgctttcccc
    11761 ttatgaagag taacaatgag gagtaacaaa aattgacaca agaagaactg cagcagttag
    11821 tagaagagat atcattaaaa agcttccagc ttcctttcaa gcaccaagca atgttcaatc
    11881 cacgcttacg tacaactggc gggcgctatc atttaaacga tcatcattta gattttaatg
    11941 cgaagctatt tgaagagtca gacgaagaga cgattgcagg aatcatcaaa catgaacttt
    12001 gccattatca tcttcatcta gctggaagag ggtatcagca taaagatatg gatttcaagt
    12061 atcttttgaa aaaaacagga gggttgcgct atgcaccagc cttgacgaag aaacagataa
    12121 agatggagta ttatcgatgc caagattgtt ctgccacgat ctgccgcaag agaagaatcg
    12181 atgtacgcaa atatcgttgt ggaagatgtc atggagaaat caaatggatt gagacaaaaa
    12241 gagaagactt taatgaagca caaaaaatca gatgaaagga tagaaggcct ttggaaaaaa
    12301 gtgagcagag gaatctaaaa gactggaatc agctattaaa ttttttagcc gcacctgaag
    12361 agggaaattt tgaggaactg acggcaccta cacttatttt agctggaaac tgtcttccta
    12421 tcttagctga taaagcagca caaatgtatt taaatggcca agtagatcaa ttgtttttgg
    12481 tcggaggggt ggggcatgcg actagaatcc tttatgagaa ttttgaaaag caaggatttc
    12541 attttgaaga tggcatgagt gaaagtgaaa tctgtcgtca gtatctaaaa gaagtctatg
    12601 atttgcccga taaggctttt ctgatagaat cgaagtctac aaattctgga gagaacgcca
    12661 ctttttcact ggagattctt cattccttag gagctgtacc agaaaaaatc ttattgatga
    12721 atgatccgac actgcaacgc aggactcgag caacttttga gaaagtatgg caaaatgaac
    12781 aaactatttt cgcgaatgct gtgccatttg tgccggaaat ccttcacttt tctgaagaga
    12841 tcatctttac agcaaaagaa ctgaatcatc aatggcctaa ggaatatttc catgcgctag
    12901 tattaggaga aatggaacgt ctccatgacg atgagaacgg ctatggtccg aaaggaaaag
    12961 attttattcc tcacattgat atatcagagg aagtttggtc ttcttacacc agaattaaag
    13021 agtcaataaa aacggatttt tctcgtactt gaccatttta gcaagcgaat cctcctttcc
    13081 aaataaattt ggttgaaatt ttcaatcgtt tataagataa tgaggagcgt gttgaatgta
    13141 atagctaaaa gaatggacgc tagataagag aagaggattc aaatggaaaa tcaaaataaa
    13201 ttgtatcatt ttgttggtat caaaggttca ggaatgagct ccttggctct tgttttacat
    13261 gaacaaggtc taaatgtcca aggatcagac attgaaaaat atttctttac acaaagagat
    13321 ttagaaaaag caaatatcac gattctgcca tttaacgcag ataatgtaaa accagggatg
    13381 acgatcattg caggaaatgc atttcctgat tcacatgaag aaatccagcg agcaaaagaa
    13441 ttaggtttgg aagtgattcg ctatcacgac tttattggtc attttatcca aaattatacg
    13501 agtatcgctg taacaggctc tcacggaaaa acaagtacga ctggactgct ctctcatgta
    13561 ttgagtggtg tccgtccaac aagttatcta attggagatg gaacaggaca tggtgatccg
    13621 caagcggaat tcttttcatt tgaggcctgt gaatatcgcc gtcatttcct tgcctattca
    13681 ccagactatg caatcatgac caatatcgat tttgatcatc cggattatta tacaagtatc
    13741 gacgatgtat ttacagcttt ccaaacaatg gctggacaag tgaaaaaagc tatttttgcg
    13801 tatggtgacg atgcttattt acgcaaatta aaagcaaatg tgccgattta ttattatggt
    13861 gtcacagaaa acgatgatat ccaagcacga aacatcgaac gcacaacttc tggttctgct
    13921 tttgatgtct atcatgggga tgaatttgtt gggcacttca ctgtaccagc attcggtaaa
    13981 cacaatatct taaatgcttt aggtgttatt gcagtagctt atttcgaaaa actggatctg
    14041 aaagaagttg cagaagaaat gctgactttc ccaggagtaa aacgtcgatt cagtgaaaag
    14101 atcgtagcag acatgaccgt agtcgatgat tatgcgcatc accctgcaga gatcaaagca
    14161 acgattgatg gcgcacgcca aaaatatcca gataaagaaa taattgcagt tttccaaccc
    14221 catacgttta cgcgtacgat tgcattgatg gatgaatttg cagaagcact tgatttagct
    14281 gataaagttt acttatgcga tatttttggt tcggctcggg aagaacaagg aaacgttaag
    14341 attgaagacc ttggagcgaa aatcaaaaaa ggtggagaag tcatcaaaga aaataatgta
    14401 tctccattgt tagattatca tgatgcagta gtaatcttca tgggtgctgg agatgttcaa
    14461 aaatttgaac aagcgtatga aaaactttta agcagcacga cgaaaaatgt actgtaatac
    14521 aattactgca gtgtccttat aaaaatagaa agagggggag tggcaaaaat cttgccaagc
    14581 cccctttttt gcaacttatg ataaacggtg ttcaaaagct tgcatctgcg gtaataagcc
    14641 caatcaaatc aaaaacatga gaagctgttt tttcttggct gttcttatta tttgatgcag
    14701 gacagctttt tcacgacctc tgtaaactat aggaatctgt taaatcaagg gagcagaact
    14761 tgccttttac gctacttttg gtacaataat gtatgattaa aaataaactg gagggtttct
    14821 atcttgaaca taggtaagcc gagaaaacta ggaaaaacaa taaatgaaat cgaggaaggc
    14881 gactcgttat ccttaacaga atctattgaa gataaccagc ttttgctgta tttgggattg
    14941 acgaatgatg caaatccttt gtatatccaa catgactttg cacaaaaaac agaatatcaa
    15001 cagccaatcg ttccatcagt gatgctgatg gggatcatca caagtgcaat ttcaaagcat
    15061 cttcctggac caggatcaca tgttgtcaat ttttctgtca attttattga accggttttc
    15121 cattatgaaa cactgacttt tcagtttgag gtcataaaag tagataagat gaaggatgtg
    15181 gtgacgattt ctgtagaagc ggagaatacg aacgaagatc gtgtgttgga tgctgtcgtt
    15241 atggtccaac cgccacaagt tcctgaattg gaaatagcaa tcgaaagtga aggtgaattg
    15301 aatgaataat ccaagtacat caatgtcagg tatcaatcgt ttttatgcaa aagtttatgg
    15361 atttttaggt atgggacttg cccttagtgc agtcacttct tacttggctc tttgggtatt
    15421 tcctttgcaa ttagcaactt ttatcaataa ttttccacta ggctttgtgg gtctgtggat
    15481 cgttgaactg attttagtaa tggttctagg cgtaaaagca caaaagaatc cgagcttagc
    15541 aatcggtgga tttattgcct actctctttt gaatggcata acattagcgg ttactcttgc
    15601 atactacgat attggaacag taacgcaagc tttcttgaca gctactttga tgttcatggg
    15661 gatgtctgtt gtcggagtaa caacaaaaag agatcttagc ggggttggaa gagcaggaca
    15721 ggcagcttta atcggagtga tcattgcact agtcttgaac atcttcattt tgagaagtag
    15781 cgtagttgag ctgttcatct ccctactgtt agtcgtcatc tttgcaggga ttacagctta
    15841 tgataaccaa agcatccgta atatctatgt ccagacaaac ggaacagcac atagtggaat
    15901 tgctgtattc atggcattga agctgtattt ggactttatc aacttgttct tggcgtttct
    15961 gagaatcttt ggacggaaca actaaaaaag aaaaaaattc atcagttggg gctataccga
    16021 attatttggt atggtcccgc tttttctttt cgcattccgc aggattcttt gttagaatga
    16081 ataagaactt tacagtaagg agttaagaag atgacaaaaa ataaattatt actcgttgat
    16141 gggaacagtg tggcttttcg cgcattcttt gcgcttcaca attctcttga acgtttcaaa
    16201 aatagaaacg gtcttcatac aaatgcaatc tatgcattca atacgatgtt tgaaaatgtt
    16261 atgcaaaaag agcaaccgac tcatgttctg gttgcgttcg atgcaggaaa aacgactttt
    16321 cggacagaaa tgtatgcgga gtacaaaggt ggaagatcca aaacacctgg cgaattcaaa
    16381 gaacaaatgc catatatacg tgatttgttg acaggactag gggtacagta ttacgaattg
    16441 cccaattatg aagcagatga tattatcggt actttggcag aaaaagtaga caaagatcaa
    16501 tttgatgtcg tcgtgctttc aggtgatcgg gatttgactc aattagctag taaagaagta
    16561 aaagtggata tcactgtaaa aggtgtcagc gatatcgaaa gctatacacc agaacatgta
    16621 gcggaaaaat atgatgggtt gacgccaaaa cagattattg acatgaaggg actagccgga
    16681 gatgcctctg acaatatccc cggtgtgact aaaatcggtg aaaaaacagc tatcaagcta
    16741 ttgaaacaat atggctcagt cgaaggaatt tatgaacata tcgatgaaat gaagcaaagc
    16801 aaaatgaaag aaaatctgat aaatgacaaa gagcaggctt tcttatcgaa aaaattggcg
    16861 accatcaata cttcagcgcc tgtggatgtc tctatcgact cattgaagta tgaagggaaa
    16921 aatctcgata aactcgttcc gttttataaa gaaatggatt tcaatcagtt cctttctaaa
    16981 ttgaatatcg tagaagaaga agtaaaaatg gatgatattt tgtttgaagt cgttcatgaa
    17041 ttcaaagagg aaatgtttac tacggatatg gcgttgtacg tggaaatgat gggcgacaat
    17101 tatcatacag aggaaatcgt cggagtagcg tgggggacag aaaagaaaat ttatgtcacg
    17161 aacgatctat ctgtattcga aaaccgagcg ttccattctt ggatcactga tccgactcgg
    17221 ctgaaaaaag tatatgatgc gaaacgaact tatgttgctt taaaccgcta tactggaaaa
    17281 acgaaaggaa tcgattttga tgtcttgcta ggtgcatacc ttctcgatac gaatgaaaaa
    17341 agcacagata tcgaaggaat agctgctcat tacggataca acgatatcca atcagatgaa
    17401 gctgtatacg gcaaaggggc gaaaaaaggt ttaccagaag aagaggaact cttttttgct
    17461 catttagcgc gaaaagtagc tgcaatcaat gcgttgacac caaaattgag ccaagaactg
    17521 gcagaaaaaa accaagaaga tcttttccgg aaaatggaac tgccattgtc tatcattttg
    17581 gcagagatgg aaataagcgg gatcaaagta gatgcgactc gcttacaaga aatgaagggc
    17641 gagttctctg ctcgcttaag agagatcgaa caaaaaatct acgaagaagc cggcgaagaa
    17701 ttcaatttga attcaccaaa gcaattagga gtgatcttat ttgaaaaaat gggattaccc
    17761 gttatcaaaa aaacaaaaac tggatattcc acagccgtag atgtactgga acagcttcgt
    17821 gaacaagcac caatcgtaga ggatatcctc acctatcgtc aaattgcaaa aattcaatct
    17881 acctatgtcg agggactgct gaaagtgatc caatcagatg gaaaagtgca tacccgttat
    17941 gtccagacat tgacccaaac aggacgatta agctctgttg atcctaattt gcagaacatc
    18001 ccgattcgat tagatgaagg gagaaagata cgtcaggcat ttgttcctag agaaaaagac
    18061 tggctgattt attcttctga ctattcacaa atcgagttac gcgtacttgc gcatatctca
    18121 aatgatgaac atttgaaagc tgccttccta gaaggtcaag atatccatgc cagcacagcg
    18181 atgcgtgtat ttggaatcga aaaggcagag gatgtcacac caaatatgcg taggcaggca
    18241 aaagcagtga attttggtat cgtgtatggc atctctgatt acggactttc acaaaatcta
    18301 ggaatcagcc gaaaagcagc acagcaatac atcgatacgt actttgaaaa atacccaggt
    18361 gtcaaagaat atatggaaag aatcgtacgc gaagcaaaag accaaggcta cgtcgaaacg
    18421 ctgtatcacc gccgtcgata tctgccagac atcaattcaa gaaattacaa tatccgttct
    18481 tttgcggaac gaacagctat caatacacca atccaaggaa gtgctgctga tattttgaaa
    18541 atcgcgatga tcgaattgga taaacgatta aaagaaacag gtcttcaagc tacgatgctg
    18601 ttacaagttc atgatgaact tgtcttcgag gtaccggaaa aagaacttga atcattagat
    18661 aaattggtga aggaagttat ggaacaagct gtttctcttc atgtaccact gatcactgac
    18721 agcagttggg gaaaaacgtg gtacgaagca aaataaacat tgtttaagac agagcaatat
    18781 aatgaaggtg aaaagaaaaa atgccagaat taccagaagt agaaaccgtt cgtaaaggat
    18841 tggaacggtt agtagtagga aaaacgattc aaaaagttca ggtcttgtgg cccaagatca
    18901 tcgagcaacc agagacaccc atctttgagg cttctcttgt tggcgaaacc atccaatcca
    18961 ttggacgtag agggaagttt ttaatttttc atctcgatca ttgtgaactg atctcacact
    19021 tgcgaatgga aggaaaatat caatttacga aagaaaatac accaatcgat aaacatacgc
    19081 atgtactttt cttttttgag gatggaagcc aacttcgcta caacgatgta cgaaaatttg
    19141 gtcgtatgac aatcgtcgaa aaaggagcaa gtgcaactta ccgaggaatc atgaaattgg
    19201 gacctgagcc tttgccagat agcttcttat tagcagattt cgcaaatgga ctgaaaaagt
    19261 cccacaaagc aatcaagcca ttgctgctag accaacgtct agtgactggt ctaggtaata
    19321 tttatgtaga tgaagcatta tgggaagcga agatccatcc agaacaaccg gcgaacacac
    19381 tgcgccccaa agaggtagaa caattacgtc tatcgatcat tgatgttttg gatcgtgcaa
    19441 tagaagccgg aggtaccacg attcgcagtt atttgaatgc attaggagaa tcaggcggat
    19501 ttcaagtagc actgcatgtc tatcagcaaa ctggcaaacc atgtatacgt tgtggaacgc
    19561 cgatcgtgaa aacaaaagtg gcacaaaggg ggacgcacta ttgtccgaat tgtcaaaggc
    19621 taaaaatcgc aaagtaggat ttgttttagg tttgacgggt ggaatagcta ccggtaaaag
    19681 tacggcagcc aaagtctttc agtctcatgg atttcctttg atcgatggcg atgtgattgc
    19741 cagagaaact gttgagcctg gaacgcttgc tctgaggaaa attgtatcag tgtttggcca
    19801 agaggtattg cagcctgatg ggcaactaga tcgagggaaa cttgggatga ttgtttttcc
    19861 atcaaaggaa aaacggcaaa aacttgatca gctattagat ccgtttatcc gaaaagcgat
    19921 aaaagatcaa atcgcctctc taagttccaa tcatccttta gtaattgtag atatcccatt
    19981 gctctacgaa ggtcattatg accactatat ggatgcagta gctgtcgttt atactacgcc
    20041 agaaactcag cttcagcgtt tgatgaaacg taatcaactg acgctagaac aagcgcagca
    20101 gagaattagt agtcaacttc caatcgaaga aaaaaagcag cgtgcggata ttttgttcga
    20161 caacaatgga acaaaagaaa tacttgtggg acaaatcgaa aattggcttt ttgctaatcg
    20221 ctttctttga gtatctgtgt caattttgct atcctgagta tatagaaagt gagggatagc
    20281 gatgggatca ttaaaaaatc aaaaggataa agtcgtaggt aacgcaaaag aaaaaatcgg
    20341 cgagatgctc aataaagaaa atctaatcga tgaaggtcgt acgcaatcag aaacagcaga
    20401 agaaaaagaa aagcagtacc aagcaagaat cgatgaaata gaagaccagc aggcagaaga
    20461 agaagcgaag cggcaagatt tgactcaaga acgaaaaaat ccgacacctg atcgtagtaa
    20521 aacaccgctc ccagaaagtg accacattcc cgatgagcaa aaaatcgagg aacagcgaat
    20581 gaaacactat acaggaatcg aagagaagtt ataaaatagt aaaaaatcga gatgtgactt
    20641 gaagcagatg agaaggtgtt catctgcttc aagttttttg tgctagatga ctaaatcagc
    20701 ttttgtgtaa gttatttctc agtaatcaag gtgatcagta ttggaaaatt gaaatttagt
    20761 aaggacaggg gacacaatta cgcatgaaag tagaaaaaat tgttcttata tccgtgtttt
    20821 ttgggtagga cagtcgcgtt tgtgatttgt ttcgtgttat aatacaacta gttgtaaaga
    20881 aagacacatc ctttatataa aatgcgatgc aagaggtgag acaaaatgag atgtcccaga
    20941 tgtcaacata ataattcacg agtaatcgac agccgtcaag cagatgatgg acgtgcgatc
    21001 cgtcgccgtc gcgaatgtga gaattgttcg ttccgattca ctacatttga acgaattgaa
    21061 gctgctccgt tattagtaat caagaaaaac ggggaacgcg aagagttcaa tcgcgataaa
    21121 attttaagag gactcatccg ttcagcagaa aaaagacctg tagctatgga acaaatggaa
    21181 caaatcgtca accatgtcga aaaccgcgta cgcagtctcg gagaaaacga agtatcgacg
    21241 aatctaattg gtgaatatgt gatggaagat ttagttgatt tagacgaaat cgcttatatt
    21301 cgttttgcaa gtgtttatcg ccagttcaaa gatatgtctg ttttcttaaa agagttgcaa
    21361 gatatcgtgg ataaagcaaa agaaaataat aaagagaata ataaagaaaa caattaagaa
    21421 acaaaaagga ggcatttcct tggaaaatgc ttggaaagag cttcaaccaa aaaatattta
    21481 ccaaggaaga aaagcggctc cgctgagaga agacagcaag aacgccttgc tgtatcttta
    21541 tcagccacta atcggcggag aagccttgag tatctatttc accctgttat cagaaatctc
    21601 tcaagaatct ggcaaaggtc ctgaagggat gcatgcagat ctgcttagta gtctaggctg
    21661 cggtatcccg caattttatg atgcaagaaa aaagctagaa ggaatcggct tactggatgt
    21721 ttattttaaa gaagatagtg atctgggacc tcgttttatt tatgagctgt tagaaccact
    21781 cattcctaaa gcatttttca aagactctgt tctggctttt cttcttctgg aaaaagttgg
    21841 tgaacgacga ttccagaagc ttacccaatt ctttgaacct aaaaggcata cagcagaggg
    21901 atatcaaaaa atcacaaaaa aatttttaga tgtttatcgc ttcaatgaag cagtgtacgc
    21961 tgctaatcaa gaaaacatcg aatcgctgaa taaatctttt gaagaatctg aatcagtagc
    22021 attacttgaa gcagattcga cattcgattg gcagtttttg aatgattggc tggcaaaaaa
    22081 acatattgca agtcttgatg atccaatcat caaacaagtc gacatgtatc atcagcttta
    22141 cggtttcgat gaattgacac ttggcgaact gatcagtcaa tcttatgact ttagtgaaca
    22201 aaaagtatct gaaaaagaac tgcaaaaagc cattttggca atgcagagac gtccggtgaa
    22261 gcaaacaaaa gaaacagttg cggtttctga aaacagtaat gaaccctcgt caaacgaaca
    22321 tttgacaaac gcagcgcttc agctgataaa agaagcacag agcattccac cgatgaaata
    22381 tctggaagca atcaagtcag aaaaaggcgg atatgtttct aaacaagaaa actggttact
    22441 gcaagatctt gtttctcaat caggtctttc cagtagcgtg atcaatgttt tgctgaatta
    22501 tgtactagtg atcaagaata atgctagctt aaatgccagt tatgtaaata cagtggcaaa
    22561 tgaatgggca caaaagaaaa tcgccacagc agaagaagcg atccagcaca ttcggcaaat
    22621 aagtaatcaa gcaaaacaat caaaacaaaa gaagcaaaca aattatcaaa ctggcaagcg
    22681 aaatgttcga cgggaaaagc ttcctgattg ggtcaaccag ccaaaagatg aaaaacagat
    22741 cagcagcgag aaaaaagcag agattgaccg ccgttttaaa gaatacctgg caaaaaagga
    22801 gggtgatatc tagtggaaga cgtaggcaaa gaattgaaga ggatcatcag caaacgcaat
    22861 tatcaagaaa agtatgctga aatgatcgct gaagtcttaa atgatgcgga tgttcaagct
    22921 tttctaagcg cacaccaaga agaattgaca caagcggata ttgaaaaaag ttacgctaaa
    22981 ttgtatgaat tcgtgcaaga aaagcgtaaa tatcaaaaaa acgatccaac gatgatcgct
    23041 cccggctatg agccgaagct gacgttgaat tttcattatg tggatgtcac ttatgtacca
    23101 acggaagcat tgttagcacg gcaaagacaa gaagaaatca gaagccgagt aaaagcaatg
    23161 gatatgccaa aagatattca atcggcttct tttgaaaact ttgaacgtac agatggacga
    23221 ggatatgcga gcttagaagc cctagatttt gtagagaaat atactgctga tccaaaaggg
    23281 tatcataaag gactgtatct agtaggaagt tttggtattg gaaaaacata tttattagga
    23341 gcaacagcga gagaattagc gattgctgga ttcaccacga cgctagtcca ttttccgaca
    23401 tttgccgttg agatgaaaca ggcaatcgga aaagatcaag tggcagaaaa gttagatgca
    23461 gtgaaacgtt cacctatttt gatgatcgat gacattggtg cagatgcgat gagtagttgg
    23521 atacgagacg aagtattcgg tgttatcctt caatatcgga tgcaggaaca gttaccaacc
    23581 ttcttctcat cgaattttac aatggatgaa ttggaacagc atttgtccgt cactcaacgt
    23641 ggagatgaag agccgctaaa agcgaaacgg ataatggaac gcatacgtta tttgacaaaa
    23701 gaaatcgaaa tgactggtcg caaccgacgc aatggttgaa cagttgacaa gtccaactga
    23761 catttgacct agtagtaaaa gcaggtcagc gaatcattat atggacagaa atgaccggag
    23821 acaatcaccg caacaagtaa tgcagaaact taaacggagg attttttatg agggctattt
    23881 tttctagtat atctgtagtt ggtctatttt ttcttttagc aggctgcggt agcgcagata
    23941 gcaacacagg ttctgttgat tcgattgatg cgggtcaaac agtaaaaaca agcagtacga
    24001 aaacggagag acaaagcata tttgtcggaa cgattgaaag tatcactcaa gtagaagcag
    24061 aagaagaaac gcttcagttg aaactcgtcg atgtcatggc caaagaagat ccagcgaata
    24121 tgggaacgtc attcagcaat gacggagtga tcttaaatgc tactgctgaa aaaataagcg
    24181 tggacataaa tgaattgaaa atcggtgaca aagtccaatt tacattagtt gagatgccga
    24241 tcatgacgat gtctatccca ccgcaagttc ctggagattc gattattgat gtttcattga
    24301 acaaataacc aataacattt tttcaaaaat aagaaaatgt tgttttatag aacgaaaagg
    24361 tatatttttt aaggagatat gggaattttt ttattcctag tctccttatt ttatttggaa
    24421 aatgctataa ttatctagaa ggagtgaagc tatgaaccat ttagatttat ctcagcgctt
    24481 agccgcagtg ggtgactttg tccctgaatc cgctcgttta gcagacattg gatcagatca
    24541 cgcttactta cccgttgcat tgatattaag aggaaaaatc gaatatgcag ttgctggtga
    24601 agtcgttcaa ggtccttatg aatcagcacg taagcaagtc aaaaaagatg gattagaaga
    24661 ccgtatcacc gtacgccttg caaatggtct agatgctatc cagccacaag atggtattac
    24721 agctgtcacg attgcgggta tgggaggttc actgatccga gatatcctag aagctggcaa
    24781 gttgaatcaa cgcttaagcg gacaagaacg tttgatcctt cagccaaaca tcggagagcg
    24841 tacattacga tcttggctgc aagaaaatca gtataaaatc caatcagaaa aaatacttga
    24901 agaaaataaa aaaatatatg aaatcattgt agccgaaaaa gaacaaaaac cagttactta
    24961 caatgaaatg gagctgatgt tcgggccatt tctgcttgaa gagaaaagtg agatcttcaa
    25021 atcaaaatgg acaagagagc ttcaacaaag aaaagctatc cgtgaacagc tcaaacaagc
    25081 agctaatcaa gaggcacgtc aaaaacaaat cgagcaggaa atccaaatga ttgaggaggt
    25141 tttaaagcca tgacaatcag cggacgcact ttcatccaaa agtttgaaag ctattgtcct
    25201 cagtggctag ctgaagaagg agacccagtc ggactgcata tcggaacatt ggataagcca
    25261 atccaacgag taatgatgac attagacgtt cgtccagaag tggtcgaaga agcaatcaag
    25321 aaaaaaatcg atttgctgat tgctaaacat cctccaatct ttcgtcctgt aaaacggctg
    25381 gttactgatc agccacaaga aaaaatgtat gcagatttgt tgaaacatga tattgccgtc
    25441 tatgcagcac acacgaacat ggatattatt tgggatggac tgaatgactg gttttgtgaa
    25501 cttctcggta ttgaagtgga gagttattta gtaaagactc atgagattca ttataaaaaa
    25561 ctggccgttt atgtacctgt ggatcatgca cagaaaatgc gtgaagtatt agctgcagct
    25621 ggtgctggta cacaaggtga ttataccggt acaagtttta cctcgattgg acacggtcga
    25681 tttactccgg aagctggtgc acaaccagcg attgggaaag tagggaagac agaacaagtt
    25741 caagaggcaa aagttgaggt tattttgccg gaaactatcg aaaaacaagt gattcaagcc
    25801 atgcggtcag ctcatcctta tgaggaacct gcttatgatc ttttcgctat agatgaacca
    25861 gtcgaaatgt ttgggttagg acgagtaggt gaattgccgc aagaaatttc tatagaggca
    25921 tttgtagaac aagtaaaaga agcgttccaa ctagatggac tgagaatagt ccagccaaaa
    25981 aatgcaaaat cctctgtgaa gcgcattgcg atttgcggtg gaagcggtga aaaattttat
    26041 ccgcaagcaa tcgcccaaag agcagatgtc tatatcacgg gagatatcta ttatcatacg
    26101 gctcatgata tgcaaagcgc tgggttgatt gcaattgatc ccggtcatta tattgaatcg
    26161 ttatgcaagc aacgatttat cgagaaattt gaatcttgga aacaagaaga aaattgggat
    26221 attaactttt tcgtttctga aacaaataca aacccatttc aatttaatta aaaggagaga
    26281 atactatgta cgaaaatctt ttgccacgtt ttttacgata tgtcaaaaca gaaacacgct
    26341 ccgatgcaac aagcaaaacg actccatcga ctcagacaca agttgctttt gcgcaagaat
    26401 tgaaaaaaga attagaagag ttaggcttag ctgatgtttt ctataatgaa gataacggat
    26461 tcgttatggg aacattacca agcaatgttg atcatgaagt gcgttccatt ggatttattt
    26521 cccacatgga tacagcagat tttaatgcag taggagtcaa tccacaaatc attgaaaact
    26581 atgatggcga gtctacgatc gtactagatg cggaagaacg ctatacattg aatacaaaag
    26641 attttccaaa tttgaaaaat tatgaaggcc acacattgat cacaacagat ggcagtacat
    26701 tactgggagc agatgacaaa tcagggattg cggaaatcat gactgcaatg gagatcttga
    26761 tcaataatcc ttctatccct cacggtacca tcaaagtggc ttttggtcct gatgaagaaa
    26821 tcggtgtcgg agcggataaa ttcgatgttg agcaattcga tgtagatttt gcttatacag
    26881 tcgatggtgg tcctttaggt gagttgcagt atgaaacgtt tagtgctgct caagcaaata
    26941 ttacgatcca agggaaaaat gtacatccag ggacggcaaa agatacaatg atcaatgctc
    27001 tacagttagc aatcgatttt cataatcagc ttccagccga tgaagttcca gaaaaaacgg
    27061 aaggatacga aggtttcttc catttgatgg cattggatgg gaatcctgaa gaagcttcta
    27121 tgagttatat cattcgcgat catgatcgtg aaaaattcga agcacgcaaa gcacaaatca
    27181 cacatatcca agaagagttg aatcagcgat ttgatcaaga acgaatcaaa gtagatatgt
    27241 atgatcaata ttacaacatg aaagaaatca ttgaaaaaga tatgagcatc gtggaattag
    27301 cgaaacaagc aatgatcgag cttggtatct ctccagtgat cgaaccagtt cgtggaggaa
    27361 cagatggttc aaaaatctct tacatgggta ttccgacgcc aaatctattt gccggaggag
    27421 aaaatatgca cggacgattc gaatttgttt ctttacaagt aatggaaaaa gcaacagacg
    27481 tgattgtaaa aattgcagaa ttgaacacaa agagttaaaa tcgaaaaaga acagcttatg
    27541 acaaggcgtt cgtcccaatg atggaatgtc atctgtctaa ggctaaaggg caggacaatg
    27601 gaattggttg tcccgccctc ttttttgaag agtaaatagg aggtaaagaa tggaaaagct
    27661 gctagttttt tataacaaaa gttcagggaa agatgagggt gagaaattag cacgctggtt
    27721 tcaagattat gtaaaagaaa agcagccaga attatatgta gaactagctg aaactggccc
    27781 atcgattgat gatgcggaat tagtcaagaa agcagaagcc atagaagctg atactttagt
    27841 aattataggt ggagacggca cgattcatca tatcgtccaa gcgttccaaa aaacattatc
    27901 tcaataccat gtcggattac ttccaggtgg aactgtcaac aaccttgcac gtgttcttga
    27961 gattcccctc aaaaaagaag aagctgctga cgtgatcctg gaaggcaatg tacggaaaat
    28021 agactatggt caagtcaatg atgaagtcat tatctctaca ctgacaatcg gaatcttagc
    28081 agatacagca gtttggatca gtcaagaaga aaaacagcgt tacggctcgt ggatctttat
    28141 caagaagttt tttaagttat tgctgaagaa gaaaaaatat catttggatt tagaaacaga
    28201 cgaggagcat tggaaaggaa aatcccaact gttgacagtc acgatgtcta actccgtggg
    28261 cggttttaca aattttgacg actcagcgac cctagatgat ggaaaatttc atgtaacgat
    28321 cgtaccttcc ttagatattt tccgatttat tttttatttg cctagaatca tgagaggcaa
    28381 attctatacg atccccggca ttacttattt cacagccaaa cgcatgaaaa tccaagcgca
    28441 ggaaaaatct gtgggcactc gaacggatgg agacacgaca gatgatcttc cagttgaatt
    28501 atctgttgta tcaaaaggat taacagttta ttcaccaaag aaagaagaaa aagcttagaa
    28561 atagtagtta acagaaagtt ggaagaagag taatggatgt attgttacac aatcctttgt
    28621 ggttttacct tttcattgtg aatttttact tattttgtct gatggggtat gataaacatc
    28681 aggctagaac tagcggctgg cgtgttcctg agaataattt gatatttgtc agcctgttag
    28741 gcggtggttt gggaggattg atctctcgaa aagttttcca tcataaaact cggaaaaaga
    28801 agtttactat aggattcgct gcaggtgtac ttgttgattt gattctcatt tattttttcc
    28861 attaaggagc aggagatgtc gtctaaagga acgaaaacta aaatcattct gaatctgctt
    28921 ttgctgattg tgatttttgc cattatttat tatttaatca atcaatcatt tgcagatatc
    28981 tttgccgaat tgctgtctac cagtgttgtt gttttggcag cggctgttat attagggaca
    29041 gtttaccaaa tcgctgaagg gcgctcaatc aaagaaattg ctgaaccttt cgcgccgaat
    29101 tttacaacga aagatgggtt cttgacctct agctatattg cgttttaccg aatcgtttcg
    29161 tttggtacag gaacgctgat ctcggagatt tatttttata acaaaaaagg aatgaagcta
    29221 tcccagggag caggggtgac agcactccat atgattatgt acaaactggc agtgatcact
    29281 tatgcattag ctggcttggt catccaattc tctctttttt attctaatgg tccatcaatg
    29341 atctggttta tcatcgctgg tatccttttg acgatcgtga ttgttgcctt tttattggcg
    29401 atgtccgtca gcttgaatgt tcaaatattt tttgtcagct tatcgaataa gttatttaaa
    29461 agtgagcgtt tgcggaaatg ggtggataca tgcaatcagc agatctactc tttaagggaa
    29521 acggtccaaa ccattatcca agacaggact gcgctattgc ggatttatct atggaatatg
    29581 ttaaaacttg tattttggta tgtacttcct tatttgattc tgattgaaaa ccatcctaaa
    29641 atagattttc tactgaccat ttcgtttatc agctttgcag tagtgctttc aggggttatt
    29701 cctacgcctg ctggtattgg ttcctttgaa tttgtctatt tgttattatt cagaccagtt
    29761 gttggaacag ttgacgcagt ttcttcgctt ttactgtatc gtttcagttc ctttatcttg
    29821 ccatttctct atggatttgt gtatgtgatt gctgaacggc gaagagtgat caaagaagaa
    29881 ataatagaag taaaaaaaga gaataaagaa aatcaagggt aggtctttta taagatctac
    29941 cctttttatc aaatcaa
//
LOCUS       DAFLVO010000031        29860 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.031, whole genome shotgun sequence.
ACCESSION   DAFLVO010000031 DAFLVO010000000
VERSION     DAFLVO010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29860
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.031"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(157..1101)
                     /locus_tag="L1U99_001433"
     CDS             complement(157..1101)
                     /locus_tag="L1U99_001433"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBN1211981.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1397..2341)
                     /locus_tag="L1U99_001434"
     CDS             complement(1397..2341)
                     /locus_tag="L1U99_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1211982.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2562..3776
                     /locus_tag="L1U99_001435"
     CDS             2562..3776
                     /locus_tag="L1U99_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1211983.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            3798..5813
                     /locus_tag="L1U99_001436"
     CDS             3798..5813
                     /locus_tag="L1U99_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HBN1211984.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(5896..7269)
                     /locus_tag="L1U99_001437"
     CDS             complement(5896..7269)
                     /locus_tag="L1U99_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBN1211985.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7295..7579)
                     /locus_tag="L1U99_001438"
     CDS             complement(7295..7579)
                     /locus_tag="L1U99_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1211986.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7581..9596)
                     /locus_tag="L1U99_001439"
     CDS             complement(7581..9596)
                     /locus_tag="L1U99_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBN1211987.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(9775..10080)
                     /locus_tag="L1U99_001440"
     CDS             complement(9775..10080)
                     /locus_tag="L1U99_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HBN1211988.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10169..11200)
                     /locus_tag="L1U99_001441"
     CDS             complement(10169..11200)
                     /locus_tag="L1U99_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1211989.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11407..12282
                     /locus_tag="L1U99_001442"
     CDS             11407..12282
                     /locus_tag="L1U99_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBN1211990.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12434..13276)
                     /locus_tag="L1U99_001443"
     CDS             complement(12434..13276)
                     /locus_tag="L1U99_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBN1211991.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13368..15245)
                     /locus_tag="L1U99_001444"
     CDS             complement(13368..15245)
                     /locus_tag="L1U99_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBN1211992.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15242..16663)
                     /locus_tag="L1U99_001445"
     CDS             complement(15242..16663)
                     /locus_tag="L1U99_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBN1211993.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(16666..20055)
                     /locus_tag="L1U99_001446"
     CDS             complement(16666..20055)
                     /locus_tag="L1U99_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBN1211994.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20312..21703
                     /locus_tag="L1U99_001447"
     CDS             20312..21703
                     /locus_tag="L1U99_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1211995.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(21776..22423)
                     /locus_tag="L1U99_001448"
     CDS             complement(21776..22423)
                     /locus_tag="L1U99_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBN1211996.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22431..23117)
                     /locus_tag="L1U99_001449"
     CDS             complement(22431..23117)
                     /locus_tag="L1U99_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1211997.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(23123..24196)
                     /locus_tag="L1U99_001450"
     CDS             complement(23123..24196)
                     /locus_tag="L1U99_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1211998.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24418..25092
                     /locus_tag="L1U99_001451"
     CDS             24418..25092
                     /locus_tag="L1U99_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1211999.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            25097..26437
                     /locus_tag="L1U99_001452"
     CDS             25097..26437
                     /locus_tag="L1U99_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1212000.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26586..27572)
                     /locus_tag="L1U99_001453"
     CDS             complement(26586..27572)
                     /locus_tag="L1U99_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HBN1212001.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            28296..29327
                     /locus_tag="L1U99_001454"
     CDS             28296..29327
                     /locus_tag="L1U99_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1212002.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            29436..>29860
                     /locus_tag="L1U99_001455"
     CDS             29436..>29860
                     /locus_tag="L1U99_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBN1212003.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIP"
BASE COUNT         8843 a         5601 c         5373 g        10043 t
ORIGIN      
        1 aatttcatat gttcatatgt acggatacat tttcggaccg attaatttta accattctat
       61 ttatttgctt acctattaga tatcaataaa aaactgctta acagctattt cagctgttaa
      121 gcagttttag gatttttagt tcatattcat tgtttcttat aatacagtgt tcaatacttc
      181 tcttaaagca cttgttgatt tgctgaacat tgctttttct tcttcgttga ttgataattc
      241 aacaacttca cgaacaccat tttcgtcaac gattgatggc acacctgtaa agatatcttt
      301 ttcgtcgtat tcaccagtta aataagcaga tacaggcaat acagcttgtt cgttattcaa
      361 gatagctttt acgatacgtg cagtactcat accaatacca tagtaagttg cttttttacg
      421 atcaatgatc tcataagcag cattacggac tttatcagca atcacatcta attcatcttg
      481 ggcaatacga tggtcttttt ctacaatttc aaacactggt ttaccaccga cagttgtatg
      541 tgaccatgca gcaacttctg aatcaccatg ttcacctaag atatagccgt ggacgctgcg
      601 tgggtcaact tttaatttca atgcgatttc tttacggaaa cgagttgtat ccaatgttgt
      661 tccagtaccg ataacacgtg atgttggcag accagattcg ttccaagcga tatatgtcaa
      721 aatatctact gggtttgaag caacaacgat aataccgtcg aatcctgatc ccatgatttc
      781 ttttacgatt tggcgcatga ttgacgcatt tgttttaact aaatctaaac gagattgacc
      841 aggtttttgg ttgataccag ctgtgataac aacgatatca gcatctttac attcttcata
      901 gccacctgac catacagcca cattttcatc gccccaagcc ataccatcta aaaggtccaa
      961 tgcttcccct tctgcttttt cttgattcac atcgatcaat actaattcat tagagattcc
     1021 ttggttgatc attgcataag cgatacttgt tccaacaaaa cctgtaccga cgattactac
     1081 tttacgactt gtttttttca tgaataaaca gctccttttc ataactattt gttactttca
     1141 tgaaaagtat agtcttgttt attcatttta tcaacatgtt aattataata gttgttatta
     1201 taatttttga tggaaacgaa ttcctgaata cgcataacag ataaatgaca aatgtttaca
     1261 cctatatccc ctgataatac aaccaaaagt ttagaactga aaataaatcc aaaaaaattc
     1321 gctgcaacga tataataaga cagcaatcgc acctaaaaca attttccttc atatgcttta
     1381 gtgaaagatt ttcttcttaa tgtttatttc tccattcatt gggagtacat gttgaatact
     1441 tcttgaataa tttgaataaa gaagtcgttt gtttatatcc gatacgatta gcgatttctt
     1501 ccaacgaaaa actcgtttct tgaatcagtt ccaacgcaaa gtcgaatttt ttctttagaa
     1561 ccagttcttg aaaggaagca tcaaaataca ttttcaattt attactaaga tagaccggat
     1621 tgtagccaaa atgagctgct gtttctttta acgtacaaga agtaaaatgc ttatcgatat
     1681 aatctaatac tctaagcatc tcattttctg cgcatccatc tgctgatgaa aagctttgtt
     1741 gttctaataa atgagtcaat tcgatcagta atagtgatgt atagagattt aacgaacgga
     1801 tcttatgact gtatgtatca aaataaatca acagcatatt ttcaatcaaa tgcgtcaaac
     1861 gacttgtttt tccgccgcga aaatgaatga attgtgtatg ttcccctttt tcttttgatg
     1921 catttatcaa aaaagaagaa agtagattat ttgtgcttgc caaatgattc aatatctctg
     1981 tagataaggt ttcttctttt aataagatgt tgattaaaat atcctcttgc cctgtgtatt
     2041 cgattctttg agtagcttct ttatcaatga tcaccacgtc actttcttcc atctctatcc
     2101 tttctccatt aataatttgt aaacatgtac cgctatacat ataattgatt tcaacaaaat
     2161 catgtgtatg ctcgggaact tccgcatatc gacggtgttt actgatatga atatttccct
     2221 gttgaaatag atcccctcgg tggatttttg gcggtgtctg aagatggtaa gctaagttta
     2281 aatcattgat attcattcct tgttcacgct gcagagtttc gattgattct tcgttacgca
     2341 aaaaaaatgt ctaattcagc tagttccaat tgactccctc ctttttgtaa gcggtttctt
     2401 tcgcttatta gttcacgctg tactgctatt atatgcaaag ctatttttgg tttcataaag
     2461 actttctatg gttgggacat gaacttcctg tgattccgct attgagagaa taaccacttc
     2521 atactatatt tttgataagc gcttacaaaa atgaaaggaa catgcttatg aataaaaaga
     2581 tgatgaaatt ttctctgctg tcagtctctc ttattttgac ttctgctggt gcagtcacgt
     2641 ctgcaattcc cagtatgtca gctacttatg ccacgcgttc tttatctgct gttgaattat
     2701 taacgactgc tccctctttt atggtcacta tttttgtttt gattagtagt tttattgcta
     2761 ggaaaatcgg acaaaaacaa actgtgatca tcggattagt gattgcatcg atttgtggta
     2821 tcctccccct cttctcacaa agttacagta ttgtcttagc ttcaagagct ggactaggta
     2881 ttggctttgg attgatcaat tctttggcag tcagcatgat tgctgccttt tatcacggag
     2941 atgaacgagc ctctatgatt ggttttcaaa gtgcatttca aggatttggt gcagctttaa
     3001 tgacatttgt tgcaggacag ctagtacagt tcggttggca atataccttt ttagtctacg
     3061 ccatcagctt acctattctt gtcttgtttg ttttgtttgt tcctacacct gaaacaactg
     3121 aacttcaatc gcatggcaca gccccaacaa gacaagtaat caaaacgaat cctaaaatga
     3181 ttagttatgg tatttttctc ttgctggtca tcgtggtata taatgctgta tcgattaaat
     3241 tagccacagt cctgacgact tattctctag gaaacgaaac taatgcagcg aatatcttaa
     3301 caatcatgca attggcaagt atggctgccg gagtttgttt tggctggctt cagacaaaag
     3361 cacatcgcta tatgcttaca ctttctttac tactgatggg aatcggcttt gtattgattg
     3421 ccactgtgat aaacctgtat gtgattgggt ttggtgcgat cctaacagga atttcttttt
     3481 cgttattcat tccttactta ttcaaccaag taagtatcca agcgcccaag tacgcggaga
     3541 gtttcaatac ttcaatctta ttggttggcg ctaatttagg tactttcatt gcaccatatg
     3601 gtttgctctt tctctctttt gcttctcttg ggagtaaaac acttgctgtt ttcgtcaatg
     3661 gcagtatctt gctgttgatt agcgcgctta ttagccttct agtagtacac aggacgaata
     3721 gaaagacagt gataagagta gatgaagaaa taaaagaaca attgacaaca aaataaattt
     3781 gatggaggtc gtgtaaaatg acaaatgaaa aacataaaga tagatggctt tggtatcctg
     3841 gagactttga gatccgccat ggactgctac aaaatttcca acgggaagaa cgaggttttg
     3901 actggccagc gtactggtac atggatgatt gccatcggaa cgtcaagttt aagagatatt
     3961 actttcttga tcaaccttcc atgtttaaag tgacgatcca aggagttggg tatgtagaaa
     4021 ttaatggaca aaaacatcca tgtggaaaat ggctgacttg tccagctggt aaagcaaaaa
     4081 ttcgtatctt tgtaggacat acatcagggc taccagcgat gtttatcgag ggagacgaag
     4141 taaaatcaga tattggctgg acagcaagta attttattga agaatatcca gctggctgga
     4201 gtccgcttta tgtcgatatc gcaaaagatc caaatcaaat ctattatcaa aaagaatgcg
     4261 tccatccagt cactgaaacg gagattggcg gaggaatctt attcgatttt gggcgagcag
     4321 tgaatggctg tgtagaacta atatctctgg atgaccatat cgaatctatc actctatgtt
     4381 atggagagtc cgatgtagaa gctatggata tcgattattg ctactataag caaataggaa
     4441 tgacaagaaa aatgaaagct cgtaaacgcg cttttcgcta tttgtttata ccagaggttt
     4501 ctactggaat ggttcaactt caagtttttc atgaattttt atctctttcg aaacaagctg
     4561 ctttttcaag cgattcttct ttactgaatc agatctggtc agtatcagaa gaagccttca
     4621 agttatgtag tgatttgttt tttatcgacg gtatcaaacg agatcgctgg atttggtctg
     4681 gagatgcgta tcaatcattc atgatcaatc aatatctttt ttttgacgag gaaatcaata
     4741 aacgaacgat attagcatta agaggacaaa atgaaatcaa gcagcatatg aatactatcg
     4801 ttgactattc gatcttgtgg ttgattggta tcgaaaacca ctatatgatg acgaaagact
     4861 atgaattttt acgcatcgtc taccctaaga tgcaatcatt aatgagatac ttgatggagc
     4921 aaacgaatga attagggttt atttatggga gagcaaaaga ttggatattt attgattggt
     4981 ctgaaatgga taaagaagga acgcttgctg cagaacaagt cttattactg aaagcctatc
     5041 attccatgat cacttgcgga gatatcttag ctgaaacata tggagagaac gaaaattatc
     5101 atactcatct ctatcaagaa aaatatcaac tattgaaaca aaacctattt gactactttt
     5161 gggatgaaga acttggcgct tttatcgatt gctatgaatc tgggagaaga aatgtgacgc
     5221 gtcatgcgaa tattttcgct gttttattcg attttgctaa caaagaccaa cagcaatcga
     5281 tcttaaagaa tgtcttattg aatgacacta tcacacagat tactactcca tatttcaaat
     5341 tctatgaaca agatgcttta tgcaaactcg gacagacgaa tatcgtctac caaacgattc
     5401 ttgattattg gggagggatg ttatctcatg atgcggtaac tttctgggaa gaatacgacc
     5461 ctactcaaac aggaaatgaa aagtacagta tgtatggaga tccttatgga aaaagcttat
     5521 gccatgcatg gggagcaagc ccaatctatc ttttaggacg ctattttatc ggtttgtatc
     5581 caacaaagcc aggttatgaa gaatttatga tacaacctaa tctagattca tttgaaacac
     5641 tgaattgtac gctacctatc aaagatggaa agatttcgct tgaaaaaaca aaagataaga
     5701 tcgtgattac ttctgataga acaggcggaa cagtgaaaat gaatggtaaa agttatcctc
     5761 ttctagcaaa acagccactt gtcttaacaa gctattcaaa aataaatgca taaaacaaaa
     5821 aactgcttgc gacatatcag aagactttaa atcttcttct gatattgtcc aagcaatttt
     5881 tattttgaag tttgcttaat tctgttcttt agaaacaatg tttgttcttt ttccggcaaa
     5941 aagaaagcta gataatacga caagtaaaaa gaaagcgatg attccaactg tcaaggctat
     6001 ttgaccgtat tctcctagtt tcccaagtac aagtcctggt actagataat cagtatcggc
     6061 aaatgtagaa gaagcgattt taagatctcc taatactgga aggataaata atggcagcca
     6121 actaatcaat aagctattga aagcagaacc taataccgcc cctcttctac cgccagtcga
     6181 gttgccgaag acaccagaag cagctccgca gaagaaatgt cctactaccc caggaatgat
     6241 aactgtagtt tgcaagccta tcatagcaaa catggatagt gttcctacaa agaagctaac
     6301 aaaaaagcca attaatacag cattaggtgc atatggaaaa acgataggaa catctaatgc
     6361 tggtttagaa tcgggtacga gttttttagc aatcccttgg aatgctggaa cgatttctgc
     6421 caacaccatt cgaacccctt gaaggacgat aacaaaccca gctgtgaatg ttccagcttg
     6481 gatcagtgca aagattacag cgttgtctcc attgcttagt tctctttcaa caaatccagg
     6541 accagctaac aaagcaagtg cgacatatac gatcgacatc aagagcatga tcgatacagt
     6601 agaatctcgc aaaaagctga aacttttagg aatctttatg tcctctgtag aacggtcttt
     6661 gtttccaaaa aactttccga tccatccact agaagcataa ccgatatttc cggtatgccc
     6721 taacgcaact tgattgtttc cagtgatgtt cttcataaac ggttgacaaa gagcaggcgt
     6781 aatagttaat agtgttcctt cgaagacccc gcctaataag atcatccaca aatttgcagt
     6841 aaaccccgcg cttactaaaa tgactgctgt tagacaagaa acataaagca ttgcttgacc
     6901 tgtaagaaaa atgaatttat atcttgtgaa tctagcaagt aaaatattca cgatcatccc
     6961 tactagcatg atcaaagcag taggtgtacc gtattgttgc aaagcaatcg ccactactgc
     7021 ttcattgcta ggaactactc cttgagtatg cagagctgtt tggaacatcg aagcaaaagg
     7081 ggttagtgaa ttactgatta aaccagcacc gccgatcagt actaggaatc cgacaaatgt
     7141 tttgatagtt ccttggatca cttctgaaaa tttcttcttc tgaagaacga gaccaagcag
     7201 tgcaatcaaa gaaacgagga tggagggctg actgacgatt gacacaaaca aattcaacaa
     7261 tttatccatt gatagttcct cccttgaatc atttttattc ttttgacaag atcttcgtta
     7321 ctttttcttt tacttcttcg ctgtcaatga tcgattgcaa aggtacgagc ttttcatcag
     7381 gtatagaagt tagcgtatct ttcaaagaat gctcaatgaa gaaataatca gccatatcgc
     7441 tagatacact tccaacatcc gtatgactta cttcaaactc gtccacatct gctccaagat
     7501 ctgcaagtgc ttgtttgatg ttcatctcta ccataaaact tgttcctaat ccactttgac
     7561 atactgcaaa aattttcata tcattcgtct ccttttctta tgatcgctaa tatttcttct
     7621 tttgttgatg cgtgtaataa atcttgaaga ttttgtttat tagaaagtag ctttgttaaa
     7681 tttgccaaag cccgaagatg tgcctcatta tcgatagcag ctaaacagat gaacaaacta
     7741 atgggatggg ctggattatc aagcagatcc acaggttgtt gaagtttcag caaagacatc
     7801 cctacttcgt ttacgccatc ttctggacga gcatgaggta atgcgatgtg atcgccaata
     7861 tggataaacg caccatactg ctccacgcgc tcgatcatag ctttgatata actttcttct
     7921 attttatttt ctgataatag cggctgtgcg gcaaatgtga ttgcttcttg ccagtttttt
     7981 ggttgatccg ataattggat catttcttct gttaataatt cagatagcat aggacgttga
     8041 tcctccttct tttctaaaag tttgttcatt ttacgattta atacttgata gagcttttct
     8101 tcgtctacgc cttcttttaa ttcgatataa ggcagtagcg ccgacaacaa ttcttgggca
     8161 gaaggcattg aaaatcctgg tatcagccaa tctctttgta cttgattgat cagctgattt
     8221 ttttccaagt cagtcatgat tggatgcaga acatagagag actttttctt atcagtaagt
     8281 gtgagaggta cagtagaaaa aataatatcg taagaagttt cgtcaacctc gtgtaagcgg
     8341 tcagctgaat tagtctctgt aaaaaagatc atcgggaata attgctgaag ttcacttttt
     8401 aagatcaatg aagagctaat gccacttgga cagacgatca cggctcttat ttttctattt
     8461 ctttcttctg cgtccgcttt tctgatctct ccgccaaata gtatagtgaa aaaaccaatc
     8521 tcttcttcag ggatgctctt ccctattcgt ctttctaacg gaagtaatgc ttttcttgtc
     8581 atttcgtaga tggaagcata ttgatgctta atttgatcga tcatcacatt aggtaaataa
     8641 aaagaatagg aaatacgaaa ataggcaggg accaagtgat aaaagacatt catcaataat
     8701 tcacgaaacg aagcaaattc tacggccatc aggaattcca tgcgatggat gacttctgaa
     8761 gaacattcca gcaaaaaatc aagtgcaggc tcctggacat ctccttcaac gatcgatgct
     8821 aagcaaagag agaaaaatat aatctccgaa ttttgatgtt cggaatagcc aaggccagtc
     8881 aatacttgtc gactaatgtc agtgactgca agagaagcca acagttcagc atcttttacc
     8941 agttccatgg atgtttttcc aattcgaatg gttgtcaaac tcaaataata agctaattca
     9001 tccattcgat ttggtgcgaa tcgaagatct gatagtgaaa tcgttttatc tagcaaatct
     9061 ctaactttgg cgtaataatc aatggaaagg gttgcggtta aatacgtgag cccaaatctt
     9121 ccagcaagtg actgcatcaa acgagcagtg cgattttttg cttctcttct taatattgct
     9181 tctgacccta gcagcctaaa accagttttc ctagtatacg acagctgaca atcttccact
     9241 tctaattcat ttcttatctt tttgatatct gacaggactg tccctttaga aacctgaaga
     9301 aaatcttgaa aatgaaaaac agaaacagac gttgcagtcg aataaaccat caaataaaga
     9361 agatctcttc gctcttgttc ggtatacaca gcttcaaatc gagtaatatc caaaaatttt
     9421 tctgcccagt cgattgctcg gaatttcttt atacggatac gggtatcatc cacatattcg
     9481 gcaaaaggag ttaattgttt gatcgcctcg cttgtattta cttcgatgat ctctgctgct
     9541 ttttctagac tgatttctct tggtgttttc aggagataac taattttgta gttcacagcg
     9601 ctgttcacct cctacttata ttctagtatg gtagcgcttt taaatcgagg ggtgtttggt
     9661 acaacttaca gttggatttt ttttacgact gtaccgaacg atttctatcg aatggataca
     9721 gaaaaaaagc aggtgaccaa atgtctcctg cttttatgaa ttgatttcgt ccgatcaatg
     9781 atgatcatgt ttattttttg aggtcagttc ttcaaatttt tctttgacat cttcaaccgc
     9841 tttttcgata tctttttcaa agtgattggg ctcattaggc tttgtttcct cttctacaga
     9901 atttgaacca gataaagctg tttctttatt ttctgtttca ccagagtttg tgccagctaa
     9961 tgattcttct ttgtcttctg tttcaccaga attagttcct gctaaagcca cttcttcttc
    10021 tgttttaggg gccattgaac ctcttaatcg tttgtgtttt tcaccgtcat aatttgtcat
    10081 gttggttcct cctagtagtt ctatactttt tcatcgtaca ataagacagt ttatgcgtca
    10141 aaaaacaaac ccgattctta caaatatgtc atatttttcc ttctgattct tgaatgcttt
    10201 tgattccttc ttccaaaatt ttcatttgta agattgtttc ttcatctttg atgacttttt
    10261 ctgcgccatt aactaatgtc tcgtaaatcc cttcgtagac acggctgtaa tcaccaacct
    10321 cggaaattac tttttcttca tgataactcc cttgttcatc tatataggtc aatacaccat
    10381 aatgttcggg caaatcgata ccaaagtctt catgatcagg catgtaaaac attttcagat
    10441 gttcttcttg tcgatctttt gtttgtttca cgaacatccc tttttttccg taaacgacga
    10501 aacttggacg ttctttgatg cggaaataac tggattttat cgaaattttc atatttccat
    10561 agaaaaaatc cagatcgaag taatcattca ttcgtccttt ccctaaaagt tgacgtacat
    10621 catagctgat atcatctggt tcgccgaaat aagaaagaac ttgatctact gtatgacaag
    10681 catgtccata taaatagctg ttcgcagtag aaaattcatg cgtattttct ggtacttccg
    10741 gtctgaaata atcataatgc atttctactt ctaaaatatc ccctaatttt ccgctttcga
    10801 ttactttttg gactgtcaag aagtcagaat cgaaccgtct gttttggtaa cattggataa
    10861 atagaccttt ttcttttgct aatgcaaata actcttctgc ttcctttgac gtttctgcaa
    10921 aaggtttctc tactagtaca ttcttaccat gttcgagtgc catttttcca tattcataat
    10981 gaaattgact aggtgtagtg atgacaacta attggatctc aggatcatcc caaagatcag
    11041 acagctgatc agtatattcg atgtcttcga atgttttcca cactggttca gatggggaaa
    11101 aaattttttt gatattgatt ttgttcgtaa gttttcttga aaaaggcaaa tgatagcgat
    11161 ttgtactctt tccattgcca agataagcga ttgtaagcat gagtggtgcc tccttttatt
    11221 gatgttttca gtatatccta gaaaagcgca gaaagtattt ataatagcta ttctggtaaa
    11281 aaagttcaga aaaacacttg ttatcattcg gtttggtgaa attaatgttc aaagtaagga
    11341 taaaaatcaa aaagatagta gcggaaccaa gtgtttatca gtaagataga atttggaggt
    11401 cagatcatgc ttattgaaga aaaactaaca aaacaagagt tgtttaccac gacagagaaa
    11461 cggattgtcg attacatccg taggaatatc gaagctgcag tctacatgac gattgaagaa
    11521 ttagcaaaag ctacgtatac ttcccattca gctatcattc gtttatgcaa aaaaatggga
    11581 ttcagcggat ttaaagaatt ccgtttcgag ctggggcggg aagttcatca attgattgct
    11641 cagttcaatc aaacgattga tcctaatttt cctttttcaa gtgaagatag cactcagcaa
    11701 attgcaaaga aaatggcgga tttatcgatc cagtcaataa aaaaagcaca attgcagatt
    11761 gaacatgaag atttagatca aatcggtaaa gtattgaaca aggcacagcg aatctttctt
    11821 tttgcaaaag gtgattctca aatcacggca aggaaattcc agaataaaat ggtcaagttg
    11881 aataagtttt tgatcatggc tgaagaatac agtgattctt cttggaatgc agccaatttg
    11941 actagcgagg attgcgccat ttttattagc tacagcggtc gcatccatca ttatgaacga
    12001 ataatgacct atttgaagca tgtagaggcc cctaccttgc tgattaccgg aaatcagcat
    12061 tcagaaatgg ccaaacaggc tgatatgtgt cttgttatat cgcaggagga atatgatttt
    12121 gctaaagtag cgactttctc ctctcaaatt gccttcgatt acgtattaaa tacgttattc
    12181 tcagtgatat attctcaaaa ttttgaagag aatatccgca acttgaaaaa caaacaagaa
    12241 ttgatgcaaa aaggccttct taaagaatat cggaaaactt aagaaaagat cctcatttag
    12301 taataagaaa gatagtgttt gataggctct ctttgatatc atcataaaaa caggctgaag
    12361 ttttcttttt caaacctcag cctgtttgtt tacggaacga ttcgaataga tatattatag
    12421 aaatgaggaa tagctaactt ctgtttctta ttttgaacga ttgacgaaaa agatatataa
    12481 gaaggaggaa aatcagtata catgcagcta acaatccata caggaaaaat cgtttgttct
    12541 cggatacttt ctgtacttct ttttgaactt cttttgcatg ataaggaacc cggtgccctc
    12601 tgacaagtaa gcgatgactg ttgaccatat aaggtgtaca agttaggagt gtcacgaaat
    12661 cctgcccttt ttcgattctc agatcttttg tatcagtcgg ttctaccgtc ttgatctgat
    12721 cgacttgata agcgagtgtc cgtccattga tttcgatata gaaagaatca cctaaagtca
    12781 gtttcggtaa gtctgtgaac aactttgctt gaggcagtcc tcgatggctg gaaataacgg
    12841 catgtgtatt ttctcccccc gtaggataag acgttccttc caataatgag gcaccttttt
    12901 ctagcagcac agtattcgtt tcatcaaaaa ttggcaaatg gacattgatc tcagggatcg
    12961 tcaaaatacc gatcgtatgt ttctcaaaat aggttctatc ctttttcgca ggttcttttt
    13021 tcttagtaaa gggatctgca cctggatttc caccttcttt tgctaattgc tggtttttct
    13081 ttgtcatgtt ttcttggatt ttagccatga cttcttcatt ttctttgacc gcttgttgct
    13141 gataatgaga gatgatctgc tgatccagat aattattcag cgcgtcgcta acaaatggat
    13201 aagctagtat ccctattcct gagagaagca agaaaagcat cagcagatct agaagtttcc
    13261 ttttctttgg tttcatttgt gttctccttg tgatgactgt ttgataataa aagaaaaagg
    13321 agcatttgcg taatccgctg ctcctttttc caattcttgc aaaaagacta aatctgactg
    13381 tgcttgcgtc tagcaaagta cagtccagca atcagtagaa ggactactcc tgcaccgata
    13441 tacacataga ttcccttacc gcctgttgaa ggaagtgtac ctttgtgttt atttggtatt
    13501 ttttcaggag aaatcaactg tcctgctgtt acataagatt gttcatcgat agtaaatgct
    13561 acacggtttg ttaatggaac atatttttct ggcgctttcg tttcttccag atagtacgtg
    13621 ccatatttta gacctgtcac atcgattaaa ccgttacttg tggttgtaaa aaccgttgct
    13681 gattctttcg ccgataccca gctgacggct tttgtggatg ggtcgatcga taaatatttc
    13741 gctgtgtcac tatcttgatc acgaacgacg aattctgctc cagcaagtgt ttggtctgat
    13801 gtaacgtcac catctacttt aacaaatcgt ttgcccccag taacgacatc gactgacggt
    13861 ggtgtttgat catttgtatg cccgttatcg acatttgctt ggttagaaaa tcctttggtt
    13921 ggatctgctt tttcgttcaa atgcatatag taaacgaatt tcaatgtacc gccaggagtt
    13981 aatgaaggaa tataattcgg atcaactgaa accgtgaatc cgtctgtttg ctcagtgaca
    14041 gaataattta ctgggtcgat ttctttattt ccatcatata aggcataagc atacgttcct
    14101 gaagaatcat tatcaaatgt taaagcagcg tcatgagtat cgataagttt gaatgttgtg
    14161 tacttgtttt gcgttccttc tttatcagcg atacctaatg ggatattgac agaaatctca
    14221 tattgaattt tttcaccgat tgcgacatct tttccattca attgaggtgt tgttttatca
    14281 actttagacg tatcattttt gatggtcttt tctactggtg tttggctatt tgccaggatc
    14341 tcaaaaggcg tgattgtttg cttttcaatc atttccgcat tatcaggagc ttttacttct
    14401 tctaaattat attttccaac ttctaaatga ttaacgatca actggccttt ttcaatagat
    14461 gcctcggcaa agtcattgtt gccgatgtca taagaatgac cagtaatgaa atgtttggct
    14521 ttggtttgat cagttgtcca agtgtacaat ccatctgtga cactttggat gtattttttg
    14581 acgcttggtg ttccttcttc tttagaaata ataaattctg ctccatttag tgcttcgttt
    14641 tcggcagtac cgatttttgt aactttcaac gttccatcat taccgactgt atttttaggg
    14701 tagagatgga tagtatctag ttcttctgtc ccgtatttat aagagccatc tgcttgtttg
    14761 atcatctcat atacagggaa agctaaaacc atgtttgcgg cagctgacac tccgtctttt
    14821 ggttcttctt tgatcgtgta gactgcatct ttcccatttt gttttttagg taaagataaa
    14881 gtgacatttc catcagcatc tgtcgttcct gaagcaactg gtgtaccagg agtcaaagac
    14941 tggactgctt gttttgctgc atccacggac gctcctttat ctcgttgcgc ataaaattct
    15001 tgagtgacgt tataaactga aaatgaaata tcggctaatc cttggtattg atcgaattcg
    15061 ctcatttctt tcccgctgtt ttggattaaa ggatcgggta aatcagtcat tttcttttta
    15121 tgaaggatga cttgagctgc tgtctcctct gcaaacactt tttttgcgcc gaagctgttt
    15181 gtgagtaatg gtaaaataag gaaaaggact cctaacataa cgtttatttt tttatgattt
    15241 ttcatttttt cactcctgtt ctttttttga taaacaacca gattgcaaag cttgcgaata
    15301 ccataccaac aacgcctaaa agtgtatttt tcgtttcgtt tgtttttgga agaaatggac
    15361 ggctattttc ttttttattg actactttca atatactgtc cgcctcttta tcctcagaaa
    15421 gaaaagttga aatggtaaac ggaatttctg tttcacttaa aatataacca gaaggtgctt
    15481 cgatctcttt taatcgataa cttcctgttt tcaacccgga aattgaaaaa gcgccatttt
    15541 tatcggaaat caggtgaagc gcatctgatt cgttctttgt ccacttgtat ccgttggctg
    15601 tttgctggag gtaatttcct gctttgtttt taataaggaa tactgcgcca gctaatcgtt
    15661 tatctggttt atttgtctcg attttgacaa attgcttact ccctgtatat acagagactt
    15721 tctttgtact gacaccaaaa ccaaaatcca gtgttccgtt gttgttgatt tccttgttcg
    15781 cctgtgctgt actgcttagc tgcatctgat aagaaatggt cagttttttt ccagcatatt
    15841 tttccaacga agggatcgaa aataaaacat caaatccgtg aggtttcttg tgtatgacaa
    15901 agccttctgt cagcttttct ccattcgatg aaatcgttaa actattaggt aaaaacgtta
    15961 atgcttcatc cgcactatct gacaattcga acttttgata gtcaaggata tttacaggaa
    16021 ttgtcgtatg caaggaataa gtgatttttt caccaatcgt aaaatcattt ctaggctctt
    16081 ctaatacctt ctcaaaaggt ggatcagggt agtcgttttc ttcattttta ggatacaaat
    16141 ggatagttga aagtttttga ttgttttgtc catgtacagg aagaacaact accatattct
    16201 ctgccttttc tttgacgact tctggtactt tggattcaat gaaaagatac gctttatctc
    16261 ttttttcttg atctttagcg gccagagaaa aagaagcgat accatcttcg ttgttaagag
    16321 ttgtagttgt tgcttctgcg gtaaacatac cggaagacgc accgtttttt gcgatctctg
    16381 cttgtgcttc ttctaccgtt ttgccctttt cccgtagatg gtaaaaagaa tctgtgacat
    16441 cataaacttg gaatgtgaca ccatttaatc ctcgatacgt ttgtaataaa gctttttctt
    16501 gtccgtcatt tggatgattt ttcggcagtt gcccgtttgg gaaaagcaat ttgtgtaaag
    16561 taatctgaac catttctgtt tctgtttctg ttgctacctg agtaaaagct ggtttaaata
    16621 gtaacaagaa gagacacata ctaagccaac caagtttttt catatttagc tgccccctct
    16681 ttcttttttc aaaaaaagat accaaataga aaacgcacaa ccaatcatcc ctactagata
    16741 gattcctaaa cggccaattc ctcccgtttc aggtaatggt acttttgcct gattcgtgat
    16801 gtctaaagaa atctggttgt ttttggctcc tggtgacaga acagattcat gatcttgtcc
    16861 atccacttga attgacccat cttcgtgtat aactatagta actggctctt ttagaccttg
    16921 gtatccttct ggtgtaaaag tttcggtcag cgtataagtt ccaggtttta aattttcgaa
    16981 tagaaaggta tctgtttctt gtccatcttt tggcgattct aagtccattt ctggtccctg
    17041 cagtctgaat tttgctcctt ttaatgtctg tccgttgtct tcttttttgt gtaccgttag
    17101 atcaaacgct tttagtcgat tttgatgagt gagcgtccat acattatttg tcatctcggt
    17161 attttttccc gtgtaaatga tttttccata tttatcgatt tggaattcat aatttcccgg
    17221 cgaagtatca tatccggcag gaccagctgt ttcaacgact cgatatttac caggtgtgag
    17281 tgaatcaaaa ctggcaagac ctttttcatt cgttgtttgg ctgtcaattg gctgataagt
    17341 accatttgct tcttttttct gtagggaaaa tgctgctcct ttaagattta tctctttgtc
    17401 cgtcccttgc atcgcatact tacgtactgc tacaggaact tcaacaaaag gattttcaat
    17461 agtcaactgg atcgtatcat cggaagtagt gactgttttt ccatcaatgg ttaccgtacc
    17521 atcagaagcg atcttgattt cccaagtagt ctttttgctt aatccatgcc cttctggagc
    17581 ttttgtttct gtcagcgtat aggtcatttc tttttgcaat ttgacatttt ctggaagaga
    17641 ataggttccg tcgccatgat ctgttagtaa agtatcaata gaatctcctg ttaatttgaa
    17701 aacagcgcca ataagatcct tttcacctgt agaggaattt ttcgttattt tcaagtttaa
    17761 cggtgtgaat tgtttagtat ttttccatgt cattgcatct atttgttgag aatcgtatcc
    17821 tggtacaggt aattctttga ttgtttggta actgaatgct tgaccttgat tattgtattg
    17881 aggtagtgat aatatctctt gataactttc tccgctattt gcagataatt tgtcaatgtc
    17941 tgcacgttcc cacgtatttg ttgtatcttt agctggttta atgattcgaa tatatccgtt
    18001 tttccaagct gcagcatttg tcgtatgttc ccgttgaatc tcaaaagtaa cttgatctgg
    18061 acgatcagct agattgttgt caaattcttc ccataacttt ttgatgtgaa gactgactcc
    18121 gggagcttta gcagatggta taccgaattc agctaattca ttggtatcaa tgtttggctg
    18181 gaaagttgtc ctgccgttca tttgatacca gaaatttgga tggaagtcct cattttctgt
    18241 ttggattctc acttggtaat ggatttggat ttcttggtct tttcctaaat agatctgatt
    18301 gctcttgatg gtatttcctt ctatggaaat agatggagtg accgttgtag gacttgtccc
    18361 cacactcttg actgaaagtg taccaggctg ataaatgaat ggttctgcga ttggatcatt
    18421 tatttgtcca ttgcttacag ttgctgagat ctgtacagct tttttggcta ggtattcaga
    18481 gatatctgtt gcatgatcag ctgattcata gtaaagatcg cctttttcat ctgatgaaac
    18541 catttgtcgc atacgagact ctacttctgc ttttgagaga ccagctgccg gatcgctttg
    18601 aagttggatg ccaagaccat gtatttcgat tcctcgttct ttgagtgcca tcgcttctcc
    18661 gatggttgcg ataaacgtac tgtcgattct tctggataga ttgttttggt caggtgcatc
    18721 atagattctt gagattagag aagtatttcc cggccgatct tgcgtattag aaaactgagt
    18781 tccgtaataa ttgctgcttg attgtgcgtg tacccgctgt actttatagg aaaatgttgg
    18841 tacaccatcc gtcagcaaaa cgatcacttt tttatgtcca tttggaacgg atagcatgct
    18901 tcctgcatct cttagtgctt tttgtgtaaa agtaccacca tttgtccgtg aaggtgtaat
    18961 ggattttact tgatttttca ctgaatcaaa tgaacccatc tgtactgcac cgttactgta
    19021 gctatatcct tcgcttgagt agccgacata tcccatattg attttgtctg tgataccgct
    19081 atctgctaaa gtatcgacaa aacgatcgac accaatcttt acttcaccga tccgattatt
    19141 gtcgttcata cttcctgacc agtctacgac caatacgaga tcaagaggcg tgatatcttt
    19201 ttgtacattt ccacgagcat tcaaataaac atcaaacaat ccgggtgtac ttgtttcctt
    19261 tgcatacttt cgtatcgcat agtctgcttg attaccggtt cctccatatt cgatatacga
    19321 atgggtccga tcattaggat ctccattcca agaatttata ccatcccatt gatttgttcc
    19381 gtttttattg ccttgatgat caagaacatt tgtatttcct gtaggttgcc aactggcttt
    19441 aggataagtg ccctgatcat ctgttgtata ttctgtagga atcgtttgat tagatggcac
    19501 actcacagct ggcaaggata atgtaggcaa tgtaaatggg ctgacagaat tttcgttttc
    19561 ttttgatgat tcttcttcta tttcgtctgg ctttggtact gacacatctg tatctttctt
    19621 attttctgtc tcatcaataa tgtcatattc tttattatcg acgatcagct tgtttgcctg
    19681 gctgtggtaa agtgctggat cgattggaaa actcagatcg atagtttgtt tagtgtttga
    19741 tgagatttcc aacgtaattt tcccgctatt tacctgataa gcatagccat ctccttcttt
    19801 tctttccaca tcacttaagt aattttcgac tagaccaatt tctttttcta tcttttcagc
    19861 actggtgtta ttcgcattta gcttgatgtt cagtgctttt tttccagact gatccgaaat
    19921 gacttcagct gaaattgttt ctaaaactgt tggatcatct gtagtgtctg ctattgcaga
    19981 taatggcaca aagtttgata aactcaatat tatcagcatg aaaataactt tcagtttctt
    20041 ccctgtggtc gtcatttttc ccctcctttt tctttttttc tgttttgacg tgaatagtga
    20101 aaattattaa aataaacagg cgttacataa ttttatttat tttaatatga taattattat
    20161 acgaagggcg ctaaagggaa tcacaccaat tttcatacca attggtttca tttatgaagt
    20221 tgattccttc gattaatgag cgtttcattg aaagaaaagg gttgagggag aaaaacatat
    20281 gatcaggttg ttggaaggaa actatagaaa gatggaaaaa atcattcgaa ttctgtccat
    20341 ttctgacaag tggatgacta aaaaagaact tgccaaacga attggtagtt cagaatctac
    20401 atttgtaagg tatatcgaag agatcaaaat ccgctgggga acggatgtaa cgattcaatc
    20461 ttcacaaaaa ttggggtatc gtcttgaaca tttgaatgta ccagcttatt taaatgttct
    20521 gatggaaatg tcgcaaagtt ctacaaacag tcgtttatta aatgagatta ttgtcaatcc
    20581 gggtaaaacg attgagtatt attgtgaaaa aatttccatc agccggtctt cttttacacg
    20641 taagttgaaa caatgcaatc aaattttaga aagctattta ttaaaagtga tcgttgacca
    20701 aggttttcag ttaactagcc ttaaaagtga gctccagttg cgtatctttg ttaccttttt
    20761 ctttttaagt tactacggaa gacgcacgtt gccatttcca atcgaaaaaa agaagatcaa
    20821 agaaattatg gtcaagaata attgtcagat gaatttgttt caggaagaaa gcccatatga
    20881 gcaatctttc tttattatgt attttgttgt gcatctcatg agagaatccc aaggaactcc
    20941 atttgaatgg aaagctggag actcttatgt acagttgata aatatcgata aaaaagactt
    21001 cttaatcttg aaaaatctct taggaaaatt gaagtacagc agctatataa aagtagtgaa
    21061 ctattttgtc aatacgattt tttcagaatt ttcggagaaa gaaaaaaatg aaatcagtga
    21121 gcagatacga aaaaatatgt cctactgttc gttttcatcc gctgattgca aagaaaaaaa
    21181 cgaagaatat gttgttcaat tattaacgca aatttatttt ttctcccgta ttttcccata
    21241 cgatacgact catttgacga tccgtgcaac ttactttgca cagcagatgc aacaccgcca
    21301 gatacgtcta tatgctggat ttcgtgcaga acttcaattt tattccactc tactgaatca
    21361 gaatctgatt tattatttat ctagctatat cttttggatg cttatcggta atcctgaaat
    21421 tcaccattat acttctgata aaaaaatact gattatcagc gacttaagtc ttcgacatag
    21481 tcaatatatt gaagaatata tcagtgatat tcttgctgtg cataaaattc actctgagac
    21541 aactgctatt actgaagatc agctgtcgaa atacaatctt ctcgagtatg atctgatcgt
    21601 tacgaatcaa cccattttga atgcccatgt tcctcatata ttgattgatg atagtgtgtc
    21661 attcgcaaat gaagaagaac tcatccgctt attcgagtta tgaataatca aaaaacagct
    21721 atgtataaac caccctgata aaaatttcag gacaaataca catagctgtt tctttttatt
    21781 gtattccttc agcaatccaa cgagatttat agcgaaagtc ttttaacaac tcttcttttg
    21841 tccaattatt tgcaatgaga tccgtcaaag tgttcattac gagggtcatg gaaaagtata
    21901 ggaaactaac tgcttcttcc gacgattgaa tggagaaatg attgattctt aataattcca
    21961 gccatttttc gttcattgga gaatcagccg atagttctct acgtttggtt gtctgctgat
    22021 catttcgctg ggttaacaag tataaccttt gccaatagat actttcgtga tctaagtcgc
    22081 agcaccactc taaatatttt tcgatcccca aaaagaaatg ttgtttgttt tcgctaatga
    22141 attttaagat atcttgatgg actatgtgag aactgctttt gatcgtatac aaataagcat
    22201 cttccaaatc ttgaaaatat ttataaaaag caccgcgcga catccccatc ttgtcaacga
    22261 tttctgagac tttgacttgg ctgatgtgct gtgagcaaaa tatctccagt aataggtcat
    22321 cgattctctg tttctttgcg ttcgataaat tgaaaaaagt ttcttttggc atccacatct
    22381 ctcctttatc tctgattata cgtggatagc ccttcattgt catgaaggat tcattccttc
    22441 tttttctctt cttctgtcaa gtacccatct tccattcgat aaacgcgatc actccattga
    22501 atcatacgga catcatgagt aaccataata gtcgcttttt gtttctcatg agcttcttta
    22561 actagtaatt tgacgacttc atatgcatga tctgtatcca aactagctgt tggttcgtct
    22621 gctaagatca agcttggctc attatataaa gcgcgagcaa ttgccactct ctgtctttct
    22681 ccaccagaaa ggtctttagg ataactattt ttaagtgact ggatatctaa agattgcagc
    22741 aaggaatcga tttttgttga atcttctttt tttgaagtaa cttggtcaac tagttcaaat
    22801 tgttccttta ccgttaaaaa aggaatcaaa ttagagcttt ggagaataaa tcctatttct
    22861 ttaaagcgta aatctgctcg ttttttttct ggaagctcag ttagtgagtg accgttgatc
    22921 actatttctc cggaagtcgg tgtttgcaat cctcctgaaa tggtaaggaa agtactttta
    22981 cctgaaccag aaggaccaat gatgctgacg aattctcctt cctttacata aaaatcaatt
    23041 gctttcaaag ctgagacctt tgtatgacca gaaccaaatg ttttggtaac ttttttcatc
    23101 gttaatattt ttttcatttt tattaacctc ctattgctgt aattgggtct actttggtta
    23161 tcgtacgtat cgaaaacaat ccgcctagca ttgcgacaat gatcaaaatc ccactatata
    23221 gcaaccattg tgaccaaaaa acagcaaaag gcatcgcgct tggtaaaatc agactagtca
    23281 aataagcaaa caaaagagca agcagaacgc ctaccacccc aacaataaag gactgtgcta
    23341 ctaaagattt agcgatgaag aaatttttga tcccttgtgc tttcattact ccaaaaatag
    23401 cagtcttctg aagtgtcatc acgtacatga aaataccgac cacggcagca accactaaga
    23461 acaaaaagta tatcatcgca tttaaggtca tattttgggc agaatagcca ggaatacttt
    23521 caatgaatgt cccaatagtt aataactgta gacccttcga tgctttttct ttcgaaattt
    23581 tagctgaatc ctttattacg atcccattga tcggctgttc ttcttcagaa gcaaacggct
    23641 gttgtccata cttcaaagca gtccacgtat ctagggacgc atagatgacg ggagaaactg
    23701 tgtaataagt ttcaggaaag ataccgacaa tcgtcaaagg atcgtcgtaa ctgccaattt
    23761 tgatcgtatc tccaatttta tagcctgaat cagccagatt ttgagagatg atgatttcat
    23821 tctttgtttt aaattcatgc cctttcgtga gttttggtaa taaaaatgct tctttcgttg
    23881 tgccgaaaac tgtaacattt tctttgtttt ttcctttgat tgctccgctg tacaatccga
    23941 ttggtgcttt ctctcctcct tcaatgtatt tcagatctcc tcttgttaat tgtgaagctg
    24001 caaatacttg atttgcatcc tccgacaaaa caatctcttg tgcgtcccaa tcatcgattg
    24061 cttttttaaa ctcttctgaa agtccattcg ctagtcctga caacatgaat acgacatacg
    24121 caatcaagaa cataataccg acgatcaagc catatcgtaa tttagaatag cgaatttctt
    24181 tgatagctag aaacatttgt ttttcctccc tatgatagat tgatagtgac aaaatgtcac
    24241 ttgttgaata gtgtaactct aaagtgacaa tttgtcactt gtgttgtttt tttcttatca
    24301 ataaattgtc taagacatct ttcgataaaa ccttaacatg agtcataaaa aatttattta
    24361 agccttattt atgctttcca tgataaacta aagtgaccaa atcaatgagg tgggaaaatg
    24421 attaaactat tagtagtaga agacgataaa gtattatcca ataatataaa agaaatactc
    24481 gctgcaatcg gcgagataac acaagtttat gatggtagtg aaggactgtt cgagttggaa
    24541 agtggagttt atgatcttgc aatcttggat ttgatgatgc cggaaatgaa tggatatgaa
    24601 gtgttagcaa aaatacggaa agaaaaaata cagactccag tattgatttt gactgcaaaa
    24661 gatagtttgg aagataagat tgaaggattt gaacgaggtg cagatgatta tctaacaaaa
    24721 cctttctatc gagaagaact gatcatgcgc gtgaaagcat tattgaaacg ctcgctaggt
    24781 ctctttgatg aaaatgttct gaagtataag gatatcagtt gtgatttaaa aagcaatgaa
    24841 gtcttgtata aagaacaagt tttgcccata caaggaaaag agtttgaatt gctcgtttat
    24901 tttttacaaa ataagggaat cattttgaca aaagagcaga tatttgaccg gatctgggga
    24961 tttgattctg atacgacgat tacagttatt gaagtttata tgagcaactt acgaaaacat
    25021 ctgcgaagta ctggattgga taaagaaatc aaaaccttac gtaatgtcgg ttatatactg
    25081 caaagggtgt gatgcaatga atggagatat tacacgaaag caacgtagtc gcttttttgc
    25141 gacaaatgta gcagcatttg cttttatctt ttttcttttg ggattcatta ctttacagat
    25201 attaaaccaa tctgcataca gagaaacaga tctgtcatta gagaaaataa attttgattc
    25261 tcgaacagta caattagaga tacaaagata tcagcaaggc gatccctttt taaacccgac
    25321 tcaaacggaa caaaacagaa caaacatgga acagccatta atggaaccat caaatgaccg
    25381 ttttaacact caagtgatct tgtggtctaa aaatggtgag atattgaata aagcagctat
    25441 tggtgggcgt ttcaaccaaa tcaaagaatt aaaaatggat acgaaaaatc tgaataccat
    25501 ccaaaatatt gaattaaatg aagacagtgg ctcatctgcc ctctctttcc gttcgattac
    25561 gaaaaaagcg gagacgaatc aagatggcgt tgcctacatc caaattttag aaaatacaaa
    25621 tcaaatcaag aattcattag cgacttttcg cacgattatg attttgtgta tgattgtttt
    25681 ttggattctc tctattggta tcagttatta cttgtctagt ctaagcatgc gccctattat
    25741 tctttcttgg agaagacaaa aagaatttgt tgagaatgct tctcatgaat tgcgcacacc
    25801 gttaacgatt attcaaaata gtttggaaca tctttttacc aagcctaatc atactattat
    25861 tgaagaatcc gaaagcatcg ctcaagcatt gtcagagacg aggcgcctca ctggattgac
    25921 ttcggatttg ctgacaatcg ctcggaatga ttctgatcag cagctgcttt caaagcaaat
    25981 gatcaataca caagaatata tcgaacaact tgttaaacca tttcaagaga tggccatcat
    26041 agatggaaaa gagtttattc tccataacga tgcaacatta gaagtaccaa ttgatgaaaa
    26101 aaaaatccat caagttttgg ttattttgct ggataatgca ttaaaatata cgaatccaga
    26161 agataagatc attttggatt catctgttaa ccataaagaa tggctgattc acgtaaagaa
    26221 tactggccct tctatcagtg aagaagatca agcaaggatt tttgatcgat tttatcggga
    26281 agatcaatct cgggcgaaag agactggcgg atacgggctt ggcttggcaa ttgcaaaaca
    26341 ggtaatcgaa cagcatcatg gacagatttc tgtatccaat tatcttccac aaggagtcga
    26401 ttttaaagtc caattgccgt tgaagcctaa aaaataatgc ttatccctaa aaaagggctg
    26461 tgacaaaaat cttgtcacag cccttttttg ttgcgaataa acggtgttcc agaagtagct
    26521 tcttcggaaa taagccgaaa tttctttaag ctgaccactt ctgtcacaac ctctttagct
    26581 tacgcttacg attttttatt gcggtcttca atgtgtacat caccgcttgt gtcaatatcc
    26641 aattcttctc ggctaacatc ttctgtcact ttttcaacat cttcatgttc ttctttatga
    26701 atcccaactt cttcacgaat aactgtatgt ttgcttacat ctacttgctc ttctttgatt
    26761 gggatagtaa tcgtgtcatc ttccaatttt tcgtctgttc cctgtgaaga ttgatctgtt
    26821 actggtttgc gttcgatgac gatttcttca cgtttgaccg gtacttctac cgtttcagta
    26881 tcgttgacca catgtttgtg gatgtcgact tctccagttg tcacatcatg tgtatttaca
    26941 tctaattttt cttcttttag ttgaattgta tcatcatcta gatttggttt gcgatcgatg
    27001 tcttcagtct tgcttgtacc cattgtatca gtctcgccag gtacgtccat cggatcagtt
    27061 cctggtgtca tattcaatgg atccgttgta ttttgaaagc ctgtcgtgcc acctacgtcc
    27121 attggatctg ttccagtgcc agtttctaat ccagtcccca ttgtgcttgc tgggctaaca
    27181 gtatcttgtg tatccattgt atcttctgtt gtttctggct gacgatagcc ttttactgtg
    27241 atgacaaatt ttccatcaga aatatctcct ctatattgat ataaaggatc attttctggt
    27301 gtagccgtct cagaatcata ggtatcaaaa gaaaaagtat cttttatttt ttcccataaa
    27361 gaacggtctt cttcaccatc catccgattt tcatctgttt caacatctat accagacaat
    27421 ccgtcaaatc ctagtctaga tgctgcttca tcagtagtat aaataacgat atcatctcgt
    27481 tcataccctt cgttacgcaa ccgttcaatt actgataatg cttcttccct cgtactatag
    27541 cttccgatga ccgttaaatt tttctcttcc atgtaaattc ctcctagcaa atagatttat
    27601 gattggtata ttgttactta taaatttatt ctataggaga cgattgtttt ctacaaatat
    27661 ttagattgga atttgattaa aacaatttaa ttgaaatttg aaaacattta tgttaatgaa
    27721 agtcatattc taataaaatg tcatttgttt ctatatgaat ttttatgaaa aatttcatat
    27781 aatttccact cgttgtgatg gtttaattta tccaatccat caataagcaa acaacttata
    27841 taaaaaagga ttaattctca atataattgc tcctaccata gaataaatct tcatgtaaag
    27901 taatgaagta ccaactattt ctaatacttc tttaagaatt atcccaacaa tatcgttaga
    27961 caaaccatta ttgaataaat ggagagccaa tcgattctga aaaaatgttt tctaattttt
    28021 cggaaataaa agaaagagcc tcctgccatt agaacgaacc aaatccattt cattgctcat
    28081 gaagtaacca catagctaaa aagaggataa atcaattaaa agatcaaaag aatgactgca
    28141 ctaataaaat aactaaaaat gtatcttctt acttcatatc ttttagctag tacttagtta
    28201 aaaatttgct tcctaagatc aagacaaact gtctatcttc atttgatgaa atgcggtaaa
    28261 atatagaaaa tgaacactat tggagggaat ttgtaatgga cagcaaaact agaaaacaac
    28321 tgcaagaaaa gttaaagcaa cgtacacact tgctcccttc cgtctttcaa cagtttttag
    28381 aagaaaatcg ttcttccctt tcattaggca gtcgctatga atacgcaaaa gattttcatc
    28441 tgtttactga ttatttgaga aaagtatttt ctgaagaagt ggatgatcag ctgattatcc
    28501 atttagaaaa acaagattat cagaatttct tagctaaaat ctatcgacat actcgttcgt
    28561 tccaaactac agcgaaccaa gaaacggagc aattgtttga aaatagctat tacgggattt
    28621 caaggaagca atattcatta aatcattttt tacgattttt gtatcaaaaa ggactgattg
    28681 aagaagagat ttctcttttg ggtacaagtt taccggaaac aaccaaagca gctccgcgat
    28741 atatcgatgc agaacttttc aaagattttg agcatttgtt tatcccgatt gaaggctttc
    28801 aaacaagcag agaagctagc tttgaagaaa agaatagacc gaggaacctt gcaattactg
    28861 ccattcttct gtattgcgga ttaaagatcc atgaagtagt agaacttaaa cgtaaagatg
    28921 tatctttgac caagcagatt cttaatctga atagaaaaga aaacagactg aataaagtac
    28981 caataccaaa agaagcgatg ccatttctgg agaactattt taagttaaca gcacaaaata
    29041 cggacgaaaa ttcttttgtt tttcgttcct cacatgatca gcaaatttct cctcggacta
    29101 ttcgccaaat tttgagcaaa attacagtat ataaaaacgt atcgccagaa ctatgcagaa
    29161 aaacatatcg ttattatgca gaactatatt tagatgatgc tgacgcggta aattatttat
    29221 gtggtaatcg atacctctca tcccattctt ttcaagatat ctgggaaaag atggttgatt
    29281 tttcttatca cgaattagcg gcattcgttc gggtttcttc catataaaac aaatgtatga
    29341 tctttttttc acaataaact atgttattat ataaaggatt atgttacgat tatcttgaat
    29401 ttgtatatta cttaacaaaa gataatggag tgtgaatgat ggagaccata acgtattccc
    29461 ctttgaactt atttacgaat tttcaagaag ctgcagctaa cttttccgag accccgatta
    29521 tctttgatga gccactttca gctttcccag aattaggact tgaaacaact tacaaaaaat
    29581 gctgcgaaag tgtgttgaaa cgggcttatc aattggctca tcttggagtg aaatccggag
    29641 acaaagttat tatttataag agttccgctt ttgacacata ccttctagct gtttctgtgt
    29701 cttaccttgg tgcagtgcct gtcatgactt cttatcatct accaacaaca acaatggaag
    29761 tatttatcga tcgtttagaa gaccctttca ttttatttga tgatgagaca aaaaagcgag
    29821 tgagagaaat ttcaaatgga acaaaatcaa aacagattcc
//
LOCUS       DAFLVO010000032        29491 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.032, whole genome shotgun sequence.
ACCESSION   DAFLVO010000032 DAFLVO010000000
VERSION     DAFLVO010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29491
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.032"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(222..1223)
                     /locus_tag="L1U99_001456"
                     /pseudo
     CDS             complement(222..1223)
                     /locus_tag="L1U99_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321067.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
     gene            complement(1223..2005)
                     /locus_tag="L1U99_001457"
     CDS             complement(1223..2005)
                     /locus_tag="L1U99_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212004.1"
                     /translation="MLDFQSKPNIFEEMSYEEAVKWLLRQAAIHYDGSDHDAHVLATE
                     SNAGFATPETVMQARGRWLRDYKLPQKYPNILDIPPGKYATKAGWGADNPDGIEDDSF
                     VEMMVFADHDSRKLIVAFARYSGEIYIKMTHNSEPVEGYNSLGWRRVYTTSVLFEGEL
                     RKGQSVNLPDDTFRYQTLRIHYTDGDGDFVEEVKRQRYARITKANLWNGDAGVTFIEF
                     ELTIEARKITMSNGRALDISSGNVSNPAMSNNVKITKIEGVK"
     gene            complement(2022..3779)
                     /locus_tag="L1U99_001458"
     CDS             complement(2022..3779)
                     /locus_tag="L1U99_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HBN1212005.1"
                     /translation="MQETTSISKGGIVMAETQHKMVLSTTEPNNGINLVRIRQGDVLT
                     QKFVVEVVEHGKLKTFEGLVPFFINTTKFGENQPVEQKVQEYSPAQARLVYTLSEPDW
                     QWGGENTAHFSFRSLNGDGTWSEQFSTQDFTYRVISGISRSQLRDSGYVWTFEDLLRK
                     FKDYMDQGKNDWEQWLEDNREILENIDPGGMIINILNEAKGDYESLADRLNQKYQVPV
                     GSSQIRETTRFFDYDTMKYVDLVPRNLNTVVNSVNNSKFNFSFITDIHADNHNLRIDG
                     VGYKDASYLRHWRAIPQFQKLGNKTDVMIYGGDNIDGGLGSLGSDIGIIDEWSARHSM
                     LGTLKRFTNAAVAGQEKPVIICKGNHDACFDPAWRKRKGMLCNADFEEYWNGLYGGVL
                     FPDKNAAIYRFDTCDFYEGGTGDKYVDGYSDTAPGAFSAKQINAFGEWLVNVPRNYHV
                     ALVGHTPLGLSKFPVRNENMISTLIEGFKSGSPVTIDWSKLGQPNDGSFGGLKTFAMN
                     TKGAGVVVGYFCGHWHEQVEGAFGTVKMILCDVGFSHTASQVDTPDELAFYKIEVDTA
                     TRKVTSKGVGRARDFTYNY"
     gene            complement(3754..6585)
                     /locus_tag="L1U99_001459"
     CDS             complement(3754..6585)
                     /locus_tag="L1U99_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBN1212006.1"
                     /translation="MSETVYFFDHLQKLIKRKNTRSLIEVSQEKEISSDKSDLMKDTL
                     YVTTKYDKEIEDARYMAIRENESSFSLYRITKVSDPFETLEFTGLGFATNELDAYIIK
                     DIRPSGQPLKNVLDRLIEFTEGNWRVGHVEAMLPTVTATFYYVSVKEALKELQTLGME
                     FVFRCSLNSDGIKDKWIEVYEQIGEESNTRFVYGSKALTVVREIDRSSISTSMIGRGR
                     GEEVGDGYGRRIEFTDVEWKKSNGDPLDKPKGQNWLEDPESTQKYGIPQKDGSMRKRE
                     TVVVFDDIDDPTDLLKNTYSTLIDSARPLVQFKAEVTGGDVIGNTVTIHRYDKGYHYK
                     TRIYKTTFNRLTGQTNIELGDNLTQDVRKQTASIVNNINSLESSKMTFYESTEIGKYQ
                     DDIMRGAGDNGGSIYWVNGIEAGVSDSREIYETVYMDGPNIPRSRFFMVQNNSGISFK
                     QCKKGEWQTIQDVHNGDSTTAWTLDGTFNANFIRAGILSGILVQGVALKTFDDKDFQL
                     VAEGGELSFEKQVKSTGLDDVHGERLGSIVSTYGSKGINGFAVWKEPNYIFSINAGDG
                     GDRGNPIFQIPADVTADKRKYNLYGDGNFSEGNITIDGRLDVKELYVNGTKIDTNGGG
                     NSGGNDNGWNGQYPPEVTTDRDKRYWQIWATAIGAGFTQQAAAALLGNAQGESDANPT
                     ADEGNGAPGFGYGVWQWTDSSGATSGRVYMINLMTKAGISDDPDTITAQFKLLMWHAP
                     NGQWIATSAYPYTWTQFMNLTDINTAAQAFVANFERPRDPHPERTAWSQEWYDKFKDL
                     EIPVSKGYMKPIADPITVTSEFGWRTSPITGAQEFHNGIDLVNGNPNTPIFASADGEV
                     IVAGDANYFDWYGNWTVIKHADGMYTGYAHQSRVDVSKGQKVTAGQQIGLMGTTGPST
                     GEHLHFQFMDEFYPSSSGHFHNARDYIDF"
     gene            complement(6582..7349)
                     /locus_tag="L1U99_001460"
     CDS             complement(6582..7349)
                     /locus_tag="L1U99_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HBN1212007.1"
                     /translation="MYSFKDTTINLTSSKRFLPTSAMMYDGMYLEDLIDGYQTLTVEG
                     REMLSVEVEQQEIQIGSIITNQKIPSRTLKITYKLEDRDPEKLQFKFKELLNYLYRNE
                     DVEIRFHDELDYYYYGRYTSTDTVPGDSNSIISSFNVFCADPLKYTKECVSDGYIGNP
                     IQFPITPRKIEVTLSMNNSIKITNGEQNITITDAAIKTGDVLVFDFSDEQVTVNGEDC
                     TSMIDLESDFENFYLKQGQKITSNNGKLKIFYRGATI"
     gene            complement(7382..10501)
                     /locus_tag="L1U99_001461"
     CDS             complement(7382..10501)
                     /locus_tag="L1U99_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBN1212008.1"
                     /translation="MEQFSVEALLKATDSGFVKTFKDAQDAVKTFEKNSNSMTTAVGK
                     VMQGTGAAMTKYITTPLIGVGVAAAKVGGDFEAQMSRVKAISGATGDTFEQMKQQAID
                     LGAKTAFSAKESAAGMENLASAGFSAQEIMKAMPGLLDLAAVSGGDVALASENTATAL
                     RGFGLEASEAGHVADVFARAAADTNAEVGDMGEALKYVAPVANSMGISLEETAAAIGI
                     MSDAGIKGSQAGTTLRGALSRLARPTKAMQDTMDNLGVSFYDADGKMKPLKTQVELLK
                     KAFEGLTPEQQQNALVTLYGQESLSGMMALIDKGPDSLGKLTKSLKDSDGAADDMART
                     MQDNMNSSIEQMFGAFESAAIVIQKILAPSIKKVADAISGLVEKFVSAPESTQKLVVA
                     IGAIVAAIGPLIFMIGSVIIWINRVKVAFKALSESSKLFSGLSKAMGLLTNPVFLVIA
                     AVALLVVGFIYLWNTSEDFRNFWIGLWEGIKSAVSSAVEWIQNAWKSTGEWFNNLWKS
                     IKEGADNVWTTVQEAPGKAADWIKNKWTGTKEFFSNLWSSIANSASEIWNSLKEGVIS
                     VIDDLVSSAGEKWEGFKNTISTAWKTITSKIKSGFDFILKYIGPFVSSFSDVFSNIVK
                     AITSIFAEVKNIIVNAWEIIKSLIAAPLLFIIDLITGDFEQMKEDLDLIWNTLVQSVV
                     NIWTSVKNIFTEYIGAIVNSAVSLWTGFIQSISNIWNEVVYQATMIWIDLKLFFTNLW
                     IDIKYSAIQMWINLKFSIIQTWIDTKYGAIELWNNLKQWFFQTVNNIVQTLIKSWNSL
                     KQGTIDLFNNTVQGAKDIWTSFKSWIGDLITGTKDNIIQGWENLKQGTIDTFNNLVNG
                     AQEAWDNLVNAVSDTVDRVTGWFDNLKNIDLLAAGKAIMDSFLEGLQNAWKSVQDFVG
                     GIGDWIREHKGPIQYDRKLLIPAGQAIMNGLNKGLTGGFNDVQNTVGSMADFIAELFN
                     ANSDVDIAANLKNANKNIGAQVEHKINMGGSTKPAVFKINLGRQSFRLFMDDISQAMG
                     EGADINLEF"
     gene            complement(10518..10805)
                     /locus_tag="L1U99_001462"
     CDS             complement(10518..10805)
                     /locus_tag="L1U99_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212009.1"
                     /translation="MTNISDIERMTLYEYNIRMTAAQLSWLDKEKLIHELAWANQQVQ
                     AEKKVGKKTVPVYRSFEEFFNYQKIEDSIMGVSELSKQDKKFQSLLTKANS"
     gene            complement(10859..11227)
                     /locus_tag="L1U99_001463"
     CDS             complement(10859..11227)
                     /locus_tag="L1U99_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HBN1212010.1"
                     /translation="MKLKIKGKEYSFKFGTKFVRELDKVMPFVDGNMEFGMGLSAKVL
                     PELRSYNVNTLSRVLEIANRTEDESITLDELDDYIDEVKDIEKLFDEVLKELAESNAG
                     KLAVRNLNQKLKEAEKQQVE"
     gene            complement(11273..11785)
                     /locus_tag="L1U99_001464"
     CDS             complement(11273..11785)
                     /locus_tag="L1U99_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HBN1212011.1"
                     /translation="MEALKGIDVILLYRLLKKETQEAAWKMAFQTEHENGLSRDSDST
                     VTKDGNVQSLSPVEYDFSATSIVAKGDSHVDEMKQALLNGDIIEIWEINKAEQGTDDN
                     ANKYKATYYQAYVSEFTPSAAAEDNVELSLSFAVNGVGQDGYATLTEDQADVVQYAFK
                     DTVKATSTGA"
     gene            complement(11796..12188)
                     /locus_tag="L1U99_001465"
     CDS             complement(11796..12188)
                     /locus_tag="L1U99_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HBN1212012.1"
                     /translation="MIKTRDQSIFDELFKISQNKLGYKTYDYKTLEDVGYPFVEFENT
                     QTIHEVNKTDIKGSVIVVLSVWGLQKKRKQLSDMASALFNEARLIEATEGYYWALNYQ
                     ASGIQVMDDTTTNTPLKRAVVTLEFRIR"
     gene            complement(12188..12526)
                     /locus_tag="L1U99_001466"
     CDS             complement(12188..12526)
                     /locus_tag="L1U99_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBN1212013.1"
                     /translation="MKAQLEYKGIDQLMRHLKKAATLNDVQKVVKSNTAEMTERMQKG
                     APVDTGYLRRSINMNLLEAGLTGIVGPTADYAPYVEYGTRFMSAQPYVRPAFNYQKVK
                     FMAEMKALVK"
     gene            complement(12510..12836)
                     /locus_tag="L1U99_001467"
     CDS             complement(12510..12836)
                     /locus_tag="L1U99_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212014.1"
                     /translation="MRFTDEIIFVKRSSDSKYDPDLGEWVEGKPERTRTEANVTDIGT
                     DRSVTIFGSVEEGAKVIRTQPLFSIPTFDYIEIEGKTWQQKTARNPAYRNSLIVQEVV
                     LDEGTT"
     gene            complement(12833..13162)
                     /locus_tag="L1U99_001468"
     CDS             complement(12833..13162)
                     /locus_tag="L1U99_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HBN1212015.1"
                     /translation="MMIADDIKKLLKGTIDEKLEVIERRTNERMKTLLNTQEVPKEFE
                     TVVYEVSLKRFNRIGQEGMQSYSQEGLSMAFPDSDFSEYQNEIDEFKRKDQEELYKPK
                     RGRFKFV"
     gene            complement(13174..13437)
                     /locus_tag="L1U99_001469"
     CDS             complement(13174..13437)
                     /locus_tag="L1U99_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212016.1"
                     /translation="MPNQKTWTGKVGDTKTFTISAVPADASDAAAVVAATTATSSDGA
                     IATVTKNENGGFDGTIAAEGSATFTFTSGEFTTSINVTGQPAS"
     gene            complement(13455..14378)
                     /locus_tag="L1U99_001470"
     CDS             complement(13455..14378)
                     /locus_tag="L1U99_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBN1212017.1"
                     /translation="MKKKQLLPMNLQMFAQTWDPDNVLVYETKEGKIPDKYNTLILSE
                     VMENSKIMQLAKYEEMTDKEKKFEYFAEGPGAYWVGEGEKIKTSKPKWMQATMTAKKL
                     GVILPVSREYLNYKLSDFFEEMQPKIAEAFYKKFDAAALLNKENPFPQSLDGSVISAG
                     NVVEGGLTYDNILALEDKLAENEFEPNAFISNRKNRTELRSAAQTVGSNVEFIYDRST
                     NTIDGLPVVDLKSLDKGTLYAGDFNYMFYGIPYNISFKISEEAQLSTLTNEDGTPVNL
                     FEQELIALRATMDVGFMIVKDEAFGKISPKA"
     gene            complement(14391..14993)
                     /locus_tag="L1U99_001471"
     CDS             complement(14391..14993)
                     /locus_tag="L1U99_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HBN1212018.1"
                     /translation="MKKRLFMPMNLQFFSEPGDGGSGDEGQQGNLPAGSQETPPEAKE
                     ENNTGKTFSRDEVAKMIAAETNKAKAAWEKELAAKKEEAKKLAKMNAEEKLQHELEQK
                     EAEIAELKRGQALSEMTKEASKMLTDANLPHDDDLLGLIVSDDADATKQAVAVITNFA
                     SLIKRENARQTPPNEGGQFTASKNTKETVAKLAAKNRIIK"
     gene            complement(15120..16046)
                     /locus_tag="L1U99_001472"
     CDS             complement(15120..16046)
                     /locus_tag="L1U99_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBN1212019.1"
                     /translation="MNSQEYWIKREKEWQKQQIKDDKKRMAEIKSRMQYAQDAIQKEI
                     DAQWDSFSNGQKITRSEAMKRASEMDVKAFARKAKKYVKEKDFSPTANQELKLYNLTM
                     RVNRLELLKANIGLELISLFNELDKYFSNELTKAGLAELKRQAGILEMTIASSGYAKL
                     IELVINSSFLSDDVSFSDRLWMYQSELKSELDRLLVRSITMGKNPKQLASKLAEYLTA
                     EGRENTKFNTQRLMVTETTRVQVGIQERSYRDAGITQYIYIAEPTACKLCIPLNNQVF
                     DVADMQPGSNAPNMHPFCRCSTAPYIERISSR"
     gene            complement(16051..17550)
                     /locus_tag="L1U99_001473"
     CDS             complement(16051..17550)
                     /locus_tag="L1U99_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBN1212020.1"
                     /translation="MDKVNEFEYGADIHYSNDVNTNYVKFSVDSNLHYRFSSAEDLLN
                     DLDTLAAMIKHHHEYQVKRLSVLDDYYKARNTNIMDNRRRREKEKADHRSAHNFGKVL
                     CTFDVGYNTGNPIKVQIEDTNQQKEIEEFNTNNDIDGLNAELWLDMDKYGRAYEIIYR
                     DSDDTDYVDLANVFETFVVYDTTVKREPILAVRYPKTRFNKDADKQYIQPIVYTKEKS
                     ITYDETTLTAIELKNPQDEPHEYKEVPITEYSPNRFRMGLYEDVLSLIDLYDAGQSDT
                     ANYMTDLNDALLVISGDIEAAGLSTEDAIKQKEANMLLLESGTDVNGNKTSVTAGYIY
                     KQYDVNGVEAYKYRVRKDIHEISMVPDLTDDNFSGVQSGEAMKYKLFGFEQMTATKQR
                     LFKKGLMRRYRLLFSLKSSISEMDNSDLKGLRVIFTPNLPKAILEELKSLVDAGAELS
                     QETILGLASFVPDVQAELKRVNKETQKQIGIFDSDGEEVINNKKDETGG"
     gene            complement(17563..18807)
                     /locus_tag="L1U99_001474"
     CDS             complement(17563..18807)
                     /locus_tag="L1U99_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HBN1212021.1"
                     /translation="MALVDIYNPKQIDVLNKTIKNDWFITLLHGAKRSGKTKINNDLF
                     LFELRRVRKIADEEDIKEPMYILAGVSSATIQKNILQELYNMYSIEPKFDKHGNFKLF
                     GVKVVQAYTGNIGGVGAIRGMTAYGAYINEASLARQEVFAEIVSRCSGTGARILADTN
                     PDNPEHWLKKEYIDNSSKNIQSFHFELDDNTFLSERYRNNIKESTPSGMFYDRDIKGL
                     WVSAEGVVYRDFDASKHYIQSKDLPPLSNFYCGVDWGYEHWGSIVVIGETDDGTAYLI
                     EEHATQFEEIDYWVDVAKGIQERYGLRVPFYCDSARPEHVARFVREKINAKNAHKARL
                     SGVEEVAKRFKQDKLFICQDRVMKFRDEIYQYIWDKKKGEPIKEYDDVLDSVRYAIYT
                     HELLKKPKVNVNEKIKRIKRMF"
     gene            complement(18794..19327)
                     /locus_tag="L1U99_001475"
     CDS             complement(18794..19327)
                     /locus_tag="L1U99_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HBN1212022.1"
                     /translation="MVNLTPKQKAFADEYIKNGGNATQAAIKAGYSKRSARVIGKENL
                     TKPNIIQYINERLNPIEKKRKLSAEDALNELIDIWQGEVQISVSKQIDRLEKNKVIKH
                     MQYEYTPDLESKLKALDLYLKYKSLLSQTQLEKAQTEIKLMQAKLEQLQINSERSTEE
                     KLDELLEKISGELDGTS"
     gene            complement(19354..19578)
                     /locus_tag="L1U99_001476"
     CDS             complement(19354..19578)
                     /locus_tag="L1U99_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212023.1"
                     /translation="MRNYWYVSLSNKYPQPNADDPIRVVQSVQIKKKYSIIEMTREAT
                     PKEIDKYNLRYCGHGYFSEQNIQTNIERYC"
     gene            complement(19585..19797)
                     /locus_tag="L1U99_001477"
     CDS             complement(19585..19797)
                     /locus_tag="L1U99_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212024.1"
                     /translation="MNENQLRELFKTNEANKTMEATFYETQKSLALIAKQAKYFYDQL
                     ILQGFNDAQAMEFMMRTFSASNQQKE"
     gene            20147..20338
                     /locus_tag="L1U99_001478"
     CDS             20147..20338
                     /locus_tag="L1U99_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HBN1212025.1"
                     /translation="MVKNLYFVIREATNGQYYFVIKSDNNEVVATSETYLTKYSAEQT
                     INSIKNGITKDSQVIDVTK"
     gene            complement(20331..20672)
                     /locus_tag="L1U99_001479"
     CDS             complement(20331..20672)
                     /locus_tag="L1U99_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212026.1"
                     /translation="MEVEQIKYQGMDRERLIDIIEQQRLELIQKEAVCKEYKKHLEQV
                     IEYHSVEKYRSVVQKNRATSPDPRQDVSISIKTPVFNSVKSEKLESISTALVEKAAEM
                     NSLANEVSRLI"
     gene            complement(20971..21438)
                     /locus_tag="L1U99_001480"
     CDS             complement(20971..21438)
                     /locus_tag="L1U99_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HBN1212027.1"
                     /translation="MVLFDVKKYETPEAKDVDMDRTKHNVGVFLSAYLSARCRIGQPR
                     EPKVTASYSLVPPSTANNTFEAERMMIEREEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            complement(22030..22317)
                     /locus_tag="L1U99_001481"
     CDS             complement(22030..22317)
                     /locus_tag="L1U99_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012197617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212028.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKKRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVARLVDMKAI"
     gene            complement(22314..22523)
                     /locus_tag="L1U99_001482"
     CDS             complement(22314..22523)
                     /locus_tag="L1U99_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212029.1"
                     /translation="MKIYVVKFGNKFYRSDERSIGANTLFIVDILQSARWFDSLEEAN
                     QVSRRLGGLTQVYELVTVDHEEVER"
     gene            complement(22520..22717)
                     /locus_tag="L1U99_001483"
     CDS             complement(22520..22717)
                     /locus_tag="L1U99_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212030.1"
                     /translation="MKAYTIKFYGNKTYVYILSGLRLDFRGYSKEDLLESLYGYGYLN
                     EDELISLEKFTNAWTIEEEAE"
     gene            complement(22714..23040)
                     /locus_tag="L1U99_001484"
     CDS             complement(22714..23040)
                     /locus_tag="L1U99_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212031.1"
                     /translation="MNYTQQELTDLCPKHVAEFINNEVLPKYADGLNTAENVTDFMIN
                     DAIDRLIFLEIDCIAYYRLHAEVALIDPYIALSQNRKILVAYIDTKQILEGRDVEIEI
                     DEEEVG"
     gene            complement(23037..23318)
                     /locus_tag="L1U99_001485"
     CDS             complement(23037..23318)
                     /locus_tag="L1U99_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212032.1"
                     /translation="MGDMGEYWKDIKPHLKERRKQHVRKMGNSATKNIETLGFEFTHY
                     PNNHQFAINTHNGIIDYWGTTGTWIERKTKKRGKGIRSLRKYINQEDSK"
     gene            complement(23331..23549)
                     /locus_tag="L1U99_001486"
     CDS             complement(23331..23549)
                     /locus_tag="L1U99_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr domain protein"
                     /protein_id="HBN1212033.1"
                     /translation="MISLTIFWCVIGGLLAMLGAYLIYESAKGKKYTAVGIILFVVGI
                     LVAIGAEINLYLNGTTEELMWFLLWTRR"
     gene            complement(23546..23857)
                     /locus_tag="L1U99_001487"
     CDS             complement(23546..23857)
                     /locus_tag="L1U99_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBN1212034.1"
                     /translation="MDELITKVEQWAKDKGLDQADSSKQMLKTIEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLNQAYNEIKGRTGKMVDGVFVKSSDLEDS
                     K"
     gene            complement(24034..24348)
                     /locus_tag="L1U99_001488"
     CDS             complement(24034..24348)
                     /locus_tag="L1U99_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HBN1212035.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKAKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYREILNEYFE
                     ED"
     gene            complement(24348..24647)
                     /locus_tag="L1U99_001489"
     CDS             complement(24348..24647)
                     /locus_tag="L1U99_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212036.1"
                     /translation="MGKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKPKRK
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            complement(24650..24811)
                     /locus_tag="L1U99_001490"
     CDS             complement(24650..24811)
                     /locus_tag="L1U99_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBN1212037.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERIKAVMVNETARKAINLHIVNL
                     RREIRRLEE"
     gene            complement(24826..25185)
                     /locus_tag="L1U99_001491"
     CDS             complement(24826..25185)
                     /locus_tag="L1U99_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBN1212038.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            complement(25182..26033)
                     /locus_tag="L1U99_001492"
     CDS             complement(25182..26033)
                     /locus_tag="L1U99_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1212039.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSFVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            complement(26050..26883)
                     /locus_tag="L1U99_001493"
     CDS             complement(26050..26883)
                     /locus_tag="L1U99_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HBN1212040.1"
                     /translation="MSDNKRYYYLKLKENFFDSDEMVLLESMPDGYIYSNILLKLYLR
                     SLKHEGKLMFNDRIPFNSTMLATITRHSVGVVEKAVQIFRDLQLIDVLDNGAIYMSDI
                     QSFIGKSSTEADRKREYRKKIEEAKRNLITGGQVSDKCPDKTTPELEIEIEKDIDIDK
                     EEKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEY
                     VINWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKNNHKKQSQKLQYSNPSEYDDLP
                     I"
     gene            complement(26890..27576)
                     /locus_tag="L1U99_001494"
     CDS             complement(26890..27576)
                     /locus_tag="L1U99_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212041.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RIIEVRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHNIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            complement(27582..28328)
                     /locus_tag="L1U99_001495"
     CDS             complement(27582..28328)
                     /locus_tag="L1U99_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBN1212042.1"
                     /translation="MSEKEQPLKNRSDNTLFNTLYKINVKDVTEKRNNLTYLSWAWAW
                     AEVSKVCEAVDYEIYHDPETYLPYVFDKKTGYMVFTSITVNGVKRDMWLPVMDGANKA
                     MKDEPYTYEVNDYQWNNETKKKEIVGKIEKRVEAATMFDINKTIMRCLVKNLAMFGLG
                     LYIFAGEDMPEDVSMLEPATQRSKKLFLDALQLVANKYEKSIDEAIVALTDAASITAD
                     DSKWTKRDLGILKRGVNWIEDQYREETKEK"
     gene            complement(28321..28662)
                     /locus_tag="L1U99_001496"
     CDS             complement(28321..28662)
                     /locus_tag="L1U99_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212043.1"
                     /translation="MKKELSTLDQYLTDPSWGKSNIKETSNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSRKSKKTEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            complement(28841..>29491)
                     /locus_tag="L1U99_001497"
     CDS             complement(28841..>29491)
                     /locus_tag="L1U99_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HBN1212044.1"
                     /translation="AESFDKKHRHVLTAIDELKEGVAENWADLFWEDTYVHPQNKQSY
                     RIIYMNRDGFSLLAMGFTGKKALSFKLQYIEAFNKMEKELKDQLPSIPATKREMALLA
                     LAANEETNERVDAIESDLNDLKNNQLLAEPDYRTISNMVRNKIRVICNQQHLNSKAKA
                     ELFKDLNGGIKRITGAVARNRIKAKQFDDVIDFINNWMPSTATMTIIKQMELLEDE"
BASE COUNT         7912 a         6375 c         4673 g        10531 t
ORIGIN      
        1 attttgatgt cgtacaactt aaatccgcca tttattttat ccctgtcaac aaagctaata
       61 ctcatataaa atcgatctaa atttgtgatt tgataattaa cgttagctgt acctttgatt
      121 gttatttctt tccctacatc atctgttgta atatttgtac tatttgcttc caataatatc
      181 ttttctcctg gtgatgtacg atacaccaaa cgtaatttat caatagctcc tgtagttcct
      241 tcatcaaatc gaactttcgc actcagagta taggttttcc cactagcaag ctgaggtgta
      301 ttaatacgcg taaacataat aatgcttcct gtaccatcag aagtaaaatg tagcttttcg
      361 ttatccgaag ttagtgaccc gtggtaacca acgttaaaat cgctcgattt tagtttggac
      421 attaaattcg gattcccact ataatcataa ttcccgaagt cgatgctgtt actgtacatc
      481 tttttcagct tgccgaggtc gccgatttgc tgattggttt gattcatctt gtcttcaact
      541 gctttaagat tgttttgtgc cgatgtaacg ttttgagaaa cggtatcaat cttagtttga
      601 gtagcttgta gttgctctgt tacctcgtca acagtttgat caattgcttg tgtggctccc
      661 tctacaaatt catttatttg ttggtttgcc ttttcaatcg tagaatccac atttgttaat
      721 gctgcgttaa cagcatctgt tgcttcttgt ttgactccat caagtaattg ttgaaagtct
      781 gcaataaagt agtctgcttt atcttgcgct agtccgtcga ttgctgaacg cttcatacgg
      841 aaggtgaagc ctaagttatc acttgttgat ccgtctggat actcgatgta aacataagct
      901 tccaccatac cgttataagc tttcatcgct tctggcaaga tatatacgac ctgtccattc
      961 aagaagcttt cagtgatgag gtttttcgtg ataaaaggga ttggctcttt cgtgatcatt
     1021 ccatctactt catcatagat aaacatcaac aagcgcaagt tagctcctag caagtccgcc
     1081 ggtgtgccgt tctgttgttc gacgttgaac tctaacgcta tttgattatc gtatgattta
     1141 aatacaagcc ccgttgcttg caaatcgtag tctttcggct gtgtaggtac tttgatagag
     1201 ccttttttga tgacatgcgc cattatttca caccttcaat cttagttatt ttcacgttgt
     1261 tgctcattgc gggattggaa acattgccgg atgaaatatc taaagctctg ccgtttgaca
     1321 tcgttatctt tcgcgcttcg attgtcagct caaattcgat gaacgtcact cccgcgtctc
     1381 cattccataa attcgctttt gtaattcgcg cgtatctttg acgtttcact tcttctacaa
     1441 agtctccgtc accgtctgtg tagtggatac gaagcgtttg gtaacggaaa gtatcatctg
     1501 gcagattgac tgattgtcct tttcttaatt cgccttcaaa aagaacagaa gtagtgtaaa
     1561 cgcgccgcca gcctaacgag ttataaccct ctaccggttc gctgttatgt gtcattttga
     1621 tgtaaatttc gccgctataa cgagcaaaag cgacgattaa ttttctcgaa tcgtgatccg
     1681 cgaataccat catttcaaca aaactgtcat cttcaatccc gtcagggttg tctgcgcccc
     1741 atccggcttt ggttgcgtat ttgccgggcg gaatgtctaa aatgttcgga tatttttgtg
     1801 gtagcttata atcgcgtaac caacgcccac gcgcttgcat aactgtttcc ggtgtagcaa
     1861 agcccgcgtt gctttcagta gctaggacgt gcgcgtcgtg atccgagccg tcgtaatgga
     1921 tagccgcttg acgcaataac catttcacag cctcttcata actcatttct tcaaaaatat
     1981 ttggtttgct ttgaaaatct aacatttaat tgttcaccgc cttaatagtt ataagtgaag
     2041 tctctcgcgc gccctacgcc tttgcttgtc acttttcttg ttgctgtgtc aacttctatt
     2101 ttataaaacg ctaattcatc cggtgtatca acttggctag ctgtatgaga gaagccgacg
     2161 tcgcaaagaa tcatttttac tgttccaaac gccccttcga cttgttcgtg ccaatgcccg
     2221 cagaaataac ctactacaac gccggcgcct tttgtattca ttgcgaaggt ctttaatccg
     2281 ccgaacgaac cgtcattcgg ttgtcctaat ttagaccaat cgatagttac cggactacca
     2341 gatttaaacc cttctatcaa cgtgctaatc atgttttcat tgcgaacggg aaacttgctg
     2401 agacctaaag gcgtatgtcc tactaacgcc acatgatagt ttctcggaac gttcactaac
     2461 cattctccga aagcgttaat ttgtttggca ctgaaagctc ccggcgctgt atcgctgtaa
     2521 ccgtccacgt acttgtcgcc tgtgccgcct tcataaaaat cacaagtatc gaaacggtaa
     2581 attgctgcgt ttttatctgg gaacaacacg ccaccgtaca aaccgttcca atactcttcg
     2641 aagtcagcgt tgcataacat tccctttcgc ttgcgccacg cggggtcgaa acaagcgtcg
     2701 tgattccctt tgcagataat aaccggtttt tcttgtcctg ctaccgctgc gttagtgaag
     2761 cgtttgagcg tgcctaacat ggaatgtcgc gcgctccatt catcaataat gcctatatcg
     2821 ctgccgagtg aaccaagtcc gccgtcgata ttgtctccgc cgtaaatcat cacatctgtt
     2881 ttgttcccta atttttgaaa ttgagggatt gcgcgccaat gtcttaaata agaagcatct
     2941 ttgtaaccga cgccatctat acgcaagttg tgattatctg cgtgaatgtc tgtaatgaaa
     3001 gaaaagttaa atttgctgtt attaacactg ttgacaaccg tattcaaatt gcgcggcact
     3061 aggtcaacgt atttcatcgt gtcgtaatca aaaaagcgtg ttgtttctct aatttgtgag
     3121 ctgccgactg gcacttggta tttttggttt aaacgatcag ctaatgattc gtagtcgcct
     3181 ttagcttcat tcagaatgtt aatgatcata ccacctggat cgatattttc cagtatttca
     3241 cgattatctt ctaaccactg ctcccagtca tttttgccct gatccatgta atctttgaat
     3301 tttcttagca aatcctcaaa tgtccacaca tagccagagt cacgtaactg gcttctagat
     3361 attccagaaa tgactcgata ggtaaaatcc tgtgtgctaa attgttcact ccaagttcca
     3421 tcaccattaa gtgatcggaa actgaaatgt gcggtgtttt caccacccca ttgccagtca
     3481 ggctcactta aggtgtaaac aagccttgct tgcgctggac tgtattcttg tactttttgt
     3541 tcaacaggtt ggttttcgcc aaattttgtt gtattaataa aaaacggcac taggccctcg
     3601 aatgttttta gtttgccatg ttccaccact tcaacaacga acttttgcgt taaaacatcc
     3661 ccttgccgaa ttcgaaccaa atttattccg ttgtttggtt cggtggtgga taggaccatt
     3721 ttatgctgcg tttctgccat gactatccct cctttagaaa tcgatgtagt ctcttgcatt
     3781 gtggaaatga cctgaagaag atggataaaa ctcatccata aattgaaaat gaagatgttc
     3841 tccagtggat ggtcctgttg tccccatcag tccaatttgc tgaccagcag ttaccttctg
     3901 accttttgag acgtctactc ggctttgatg cgcgtatcct gtatacattc catcagcgtg
     3961 tttaatcact gtccaatttc cataccagtc aaagtaattt gcatcacctg caacaatcac
     4021 ttcgccatcc gctgaagcaa aaataggtgt attaggattt ccatttacaa ggtcaatacc
     4081 gttatgaaat tcttgtgctc ctgtgattgg agaagtgcgc cagccaaatt cgctcgtcac
     4141 tgtgattgga tccgcaatcg gcttcatata tccttttgat acaggaattt ccaaatcttt
     4201 gaacttgtca taccattctt gtgaccatgc cgtccgttct ggatgtggat cacgtggacg
     4261 ttcaaagtta gccacgaatg cttgtgctgc tgtgttgata tcggtcagat tcatgaattg
     4321 tgtccatgtg taaggataag cgctagttgc gatccattga ccatttggtg catgccacat
     4381 caacaattta aactgtgccg tgattgtgtc tggatcatca ctgatgccag cctttgtcat
     4441 taaattgatc atgtagacac gtccgctagt tgcgccagaa gaatcggtcc attgccatac
     4501 accataaccg aaccctggtg cgccattgcc ctcatcagcg gttggattag catctgattc
     4561 tccttgtgca tttccaagta aggctgcagc agcttgttgt gtaaaaccgg cacctattgc
     4621 cgttgcccaa atttgccaat atcgtttatc ccgatcagta gttacttctg gtgggtattg
     4681 tccgttccaa ccgttatcgt tccctccgga attgcctcct ccattagtgt caatttttgt
     4741 accgttaaca tagagttctt ttacatctag ccgtccatct atggttatat ttccttctga
     4801 aaaattgccg tcaccataaa gattatattt gcgcttatca gcagtaacat ctgctggaat
     4861 ttgaaaaata ggattccctc gatcgccacc gtccccagca ttaatggaaa aaatatagtt
     4921 tggctctttc cagacagcaa agccgttaat ccctttagaa ccataagtag atacaattga
     4981 gcccaagcgt tctccatgta catcatctag tccagtagac ttgacttgtt tttcaaaaga
     5041 aagttctccc ccctctgcca ctaattggaa atctttatcg tcaaatgttt ttaaagctac
     5101 cccttgcacg aggataccag acagaatgcc tgcgcgaata aaattagcat tgaaagttcc
     5161 atccaacgtc caagcggtcg tgctatcacc attgtgtaca tcttgaattg tttgccactc
     5221 acctttttta cattgtttga aagatatccc tgagttattt tggaccataa aaaagcgtga
     5281 tctaggaatg ttaggtccat ccatataaac agtttcatag atttctctac tatcactaac
     5341 accagcttca attccattta cccaataaat agaaccgcca ttatctcctg cacctcgcat
     5401 aatgtcatct tgatattttc caatctctgt cgattcgtaa aatgtcattt tgctagattc
     5461 taaactatta atattattga caatagaagc cgtttgtttt ctaacatctt gtgttaaatt
     5521 atcccctagt tcgatattcg tttgaccggt aagccgattg aatgtagttt tataaatacg
     5581 agttttatag tgataacctt tatcgtatct gtgaatagtc actgtatttc ctatcacatc
     5641 tcctccagtg acttcagctt tgaattgtac taacggtcta gcagaatcga ttaaggttga
     5701 ataagtattt ttaagtaaat ctgttggatc atctatatca tcaaacacta ctacggtttc
     5761 tcgttttctc attgatccat ctttttgtgg tatcccatac ttttgagttg attccggatc
     5821 ttcaagccaa ttttggcctt taggcttatc taaaggatca ccattcgact ttttccattc
     5881 aacatcagtg aattcaattc ttctaccgta accgtcacca acctcttcgc ctcgcccacg
     5941 acctatcatt gaagttgaga ttgagcttct atctatctct cttacaactg ttaatgcttt
     6001 actaccatat acgaaacgtg tattcgattc ttcgccaatt tgttcatata cttcgatcca
     6061 tttatccttt attccatcag aattcaaaga acacctaaag acaaattcca tacctaaggt
     6121 ttgcaattct ttcaacgctt cttttacaga gacatagtaa aaagttgcag ttactgttgg
     6181 taacattgct tctacgtgac caacgcgcca atttccttca gtaaattcaa tcaatcgatc
     6241 aagaacattt tttaagggct gcccactcgg cctaatatct ttgatgatgt aagcatctaa
     6301 ttcatttgtc gcaaatccta accctgtaaa ctctaatgtt tcaaatgggt cgctaacttt
     6361 agtaattcga tacaacgaaa aagacgactc gttttcacga atcgccatat atcttgcatc
     6421 ctctatttct ttatcatatt ttgtcgtaac gtaaagagta tctttcatta gatcactctt
     6481 atcagaacta atttcttttt cttgggagac ttcaatcaaa cttcttgtat tttttctttt
     6541 aataagtttt tgcaagtgat caaagaaata aactgtctca ctcaaattgt cgccccccta
     6601 tagaatattt taagcttccc attattgcta gttatcttct gaccttgctt aagataaaag
     6661 ttctcaaaat cactttctaa atcaatcata gaagtacaat cttctccgtt tacagttacc
     6721 tgctcatcgg aaaaatcaaa aaccaacacg tctcctgttt ttattgccgc gtcagttatc
     6781 gtgatatttt gttctccgtt tgtaattttg attgaattat tcatggataa agtaacttca
     6841 atttttcttg gtgttatagg aaactgtatc ggatttccaa tatagccatc actaacacac
     6901 tctttcgtat actttagtgg atccgcacag aatacattaa aactcgaaat aatcgagttg
     6961 gagtctcctg gaacagtatc agttgatgta tagcgaccgt agtaataata atctaattca
     7021 tcatgaaacc taatttccac gtcttcattc cggtataaat aattcaacag ttctttgaat
     7081 ttaaactgta gtttttctgg atctctatct tccagcttat atgttatttt tagtgttctt
     7141 gaaggtattt tctgatttgt aatgattgaa ccaatttgta tctcttgctg ttcaacttct
     7201 acagaaagca tttctctacc ttccaccgta agtgtttgat aaccatcaat caaatcttct
     7261 aaatacattc catcgtacat catggcagac gtcggaagga atcgtttaga actagtgaga
     7321 ttaatggttg tatctttgaa tgagtacatt ttattttctc gttgatccaa aatattccct
     7381 cctaaaattc cagattaata tctgcacctt cgcccatagc ttgtgaaata tcgtccataa
     7441 acaatctaaa cgattgtctt ccaagattga ttttaaatac agctggttta gtagagccac
     7501 ccatatttat tttatgttca acttgtgcac caatgttttt atttgcattt ttcaaatttg
     7561 cagctatatc tacatcagaa tttgcattga aaagttccgc gataaagtct gccatacttc
     7621 caacagtatt ctgtacgtca ttgaatcctc ctgtcagacc tttattcaga ccgttcataa
     7681 tagcctgacc agctggaatc aatagctttc tatcgtattg gataggtcct ttgtgttcac
     7741 gaatccaatc accaatacct ccaacaaaat cttgcacaga tttccatgca ttttgtaacc
     7801 cttctagaaa actatccatg atagcttttc cggctgctag taaatcgata tttttcaagt
     7861 tatcaaacca gccagttact ctatcaaccg tgtcactaac agcatttact aaattatccc
     7921 atgcctcttg agcaccattt actaaattgt tgaaagtatc tatagtacct tgttttaggt
     7981 tttcccatcc ctgaatgatg ttatctttgg ttccagtaat taaatcacca atccaagatt
     8041 tgaatgaagt ccaaatgtct ttagcacctt gaactgtatt gttgaataaa tctatcgttc
     8101 cttgctttaa gctgttccaa ctttttataa gagtttgcac gatattatta accgtttgga
     8161 aaaaccattg ttttagatta ttccaaagtt caattgcacc atattttgta tcaatccaag
     8221 tttgaattat ggagaatttt agatttatcc acatttgaat tgcactgtat ttaatatcaa
     8281 tccataaatt agtaaaaaat agtttcaaat caatccaaat catagtcgct tgataaacta
     8341 cttcattcca aatattagaa atactttgta tgaatccagt ccataaacta acggcactat
     8401 ttactattgc accgatatat tccgtaaata tattttttac agatgtccaa atatttacca
     8461 ctgattggac aagtgtgttc cagattagat ctaaatcctc tttcatttgt tcgaagtcac
     8521 cagtaattaa atctataata aacagtagtg gcgcagctat taaagactta atgatttccc
     8581 aagcatttac tattatgttt ttaacctcag caaatatact tgttattgct ttcactatat
     8641 tagagaacac atctgaaaag ctacttacaa atggaccaat atattttagt ataaaatcaa
     8701 aaccagattt gattttactt gtaattgttt tccatgcagt agatatagta tttttaaacc
     8761 cttcccattt ttcaccagca cttgaaacta aatcatcaat aactgatatg acaccttctt
     8821 ttaaactatt ccaaatctct gaagcagagt ttgcaatact tgaccataaa tttgaaaaga
     8881 actcttttgt tccagtccat ttgtttttaa tccaatctgc cgctttccca ggggcttctt
     8941 gaactgtagt ccaaacattg tctgcgcctt ctttaatgga cttccataaa ttgttaaacc
     9001 attctcctgt agatttccat gcattctgaa tccattctac tgccgagctt acagcagact
     9061 tgattccctc ccataagcca atccaaaagt ttctaaaatc ttcactcgta ttccaaagat
     9121 agatgaaacc tacaacgagt agtgctaccg cagctataac cagaaaaacc ggatttgtaa
     9181 gaagacccat tgctttactt aatccactaa acaattttga actttcactt aaagctttaa
     9241 aagctacttt caccctattg atccatataa ttactgaacc aatcataaaa attaacggtc
     9301 ctatagcagc gacaattgct cctatggcca ctactaattt ttgagttgat tctggagcac
     9361 ttacaaattt ttctactaag ccggatatgg catctgctac ttttttgatg gatggtgcta
     9421 gaatcttttg aattacaata gctgctgact caaaagctcc aaacatttgc tcgatggaag
     9481 aattcatatt atcttgcatg gtccgagcca tatcgtcagc tgcaccatca gaatctttca
     9541 gagattttgt taatttgccc aatgaatcag gtcctttatc aatcaaagcc atcatccctg
     9601 ataatgattc ttgcccatat agtgttacta aagcattttg ttgttgttca ggcgtcaggc
     9661 cttcaaaagc ttttttaagt aattctactt gagtttttaa aggtttcatt ttaccgtcag
     9721 catcataaaa cgaaacacct aaattatcca ttgtatcttg catagccttt gttggccttg
     9781 ctaacctaga caatgctcct cgcaacgttg tacctgcttg agaaccctta atgcctgcgt
     9841 cactcataat accaatagct gctgcagttt cttccaaaga aatccccatt gaattagcta
     9901 caggagcaac atacttcaat gcttctccca tgtctccaac ttcagcattg gtatccgcag
     9961 cagcacgagc aaatacatca gcgacatgtc ctgcttcact tgcttctaaa ccaaatcctc
    10021 tcaaagcagt agcagtattt tcagaagcta gagccacatc ccctccagat acagctgcta
    10081 agtctaaaag acccggcatt gctttcatga tttcttgtgc gctaaatcca gcagaagcta
    10141 agttttccat tccagcagct gattcttttg cgctaaaagc agtttttgct cctagatcaa
    10201 tcgcttgctg tttcatctgt tcgaatgtgt cgccggttgc tcctgatata gcttttacac
    10261 gactcatttg tgcttcgaag tcgccaccaa ctttagcagc tgctacgcct actcctataa
    10321 gaggagtggt aatatacttt gtcattgcgg caccagtacc ttgcatcact ttaccaacag
    10381 cggttgtcat actatttgaa ttcttttcaa aagttttaac agcatcttgt gcatctttaa
    10441 aagtctttac aaatccacta tctgtggctt ttaataaggc ttcaacagaa aattgttcca
    10501 tgattctcct cctttcctca agagttagct ttagttagta agctttggaa ttttttatct
    10561 tgttttgaaa gttcggaaac tcccatgatt gaatcttcga ttttttgata attgaagaat
    10621 tcttcaaagg atcgatatac aggaactgtc tttttgccta cttttttctc cgcttggact
    10681 tgctgatttg cccacgctaa ttcgtgaatc aacttttctt tgtcaagcca agataactgg
    10741 gctgcagtca tacgaatgtt gtattcatat aacgtcattc tttcgatatc tgagatattg
    10801 gtcattccca aatatcgaaa agaattgata agaatttgtt cgtatgccag tgcagaatct
    10861 attccacttg ttgtttttcc gcttctttca atttctgatt caggtttcgg accgctaact
    10921 ttcccgcgtt cgactccgcc aattctttta ggacttcatc aaacaatttt tcaatgtctt
    10981 taacttcatc gatgtaatca tccaattcat ctaatgtaat agattcatct tcagttctat
    11041 ttgctatttc cagaactcgt gataacgtgt taacgttata agaacgtagc tctggtaaga
    11101 cttttgcgga gagtcccatt ccaaattcca tatttccatc gacgaaaggc atcactttat
    11161 ctaattcacg tacaaattta gtgccaaatt taaacgaata ttctttacct ttaattttta
    11221 atttcaatgt ttttcatcct cctaaaataa aaaagagagc atctaagccc tcttatgctc
    11281 ctgtcgaagt tgctttcacg gtatctttga atgcatattg aacaacatcg gcttgatctt
    11341 ctgtcaaggt tgcataacca tcttgaccaa caccatttac tgcaaatgat aaacttaatt
    11401 caacgttatc ctctgcagca gccgatggag taaattcaga cacatatgct tggtaataag
    11461 tagctttgta cttatttgca ttatcatctg ttccctgttc tgctttatta atttcccaaa
    11521 tttcaatgat atccccattt aataaagctt gtttcatttc atctacatga gaatctcctt
    11581 tagcaactat tgaagtagcc gaaaaatcat attcaaccgg gcttaaactt tgaacgtttc
    11641 catcttttgt cactgtagag tctgaatctc ttgataaacc attttcgtgt tctgtttgaa
    11701 atgccatttt ccaagcggct tcctgagttt cttttttcaa taagcgataa agcaaaatga
    11761 catcaatacc ttttaatgct tccatgttct tcctcctatc taattctaaa ttcaagtgtg
    11821 acaaccgccc gttttagcgg tgtattcgtt gttgtgtcgt ccatcacttg aattccactt
    11881 gcttgataat ttaaagccca ataatagcct tctgtggctt ctatcaatct agcttcatta
    11941 aaaagagcag atgccatatc tgacaactgc tttcgtttct tctgtaatcc ccaaacggat
    12001 aaaaccacaa tcacagaccc tttaatgtca gttttattta cttcatggat tgtctgagtg
    12061 ttctcaaatt ccacaaaagg ataaccaaca tcctctaaag ttttgtaatc gtatgtttta
    12121 tatccaagtt tgttttggga tattttaaaa agttcatcaa aaattgattg atctcttgtc
    12181 ttaatcatca tttcaccaag gctttcattt cagccataaa tttgactttt tggtaattaa
    12241 acgctggtct aacataaggc tgtgccgaca taaatcgagt gccatattct acataaggtg
    12301 cataatctgc tgtcggtcct acaataccag ttaaaccagc ttctaaaaga ttcatgttta
    12361 ttgatcttcg taagtaacct gtatccactg gcgcaccttt ttgcattcgt tcagtcattt
    12421 cagcagtatt acttttcacg actttttgaa cgtcattaag cgttgctgct tttttcagat
    12481 gtcgcatcag ctgatcgatt cctttatatt caagttgtgc cttcatcaag aaccacctct
    12541 tgcacaatta aactatttct atatgctgga tttctagctg ttttttgttg ccaagtcttt
    12601 ccttcaatct cgatatagtc aaatgtaggg atagaaaaaa gaggctgcgt cctaatgacc
    12661 ttcgcccctt cttccacact accaaaaata gtcacacttc tatcagtgcc aatatctgtc
    12721 acgtttgcct ctgttcttgt tctttctggt ttgccttcaa cccactcacc gagatctgga
    12781 tcatatttag agtcagatga acgtttaaca aatataattt catctgtaaa tctcatacaa
    12841 atttaaacct ccctcgcttt ggcttgtaca actcttcctg atctttacgc ttaaattcat
    12901 caatctcatt ttgatactct gaaaaatccg agtcaggaaa agccatagat aaaccttctt
    12961 gagaatatga ctgcatacct tcttgaccaa ttctattgaa tcttttcaac gatacttcat
    13021 atacaactgt ttcaaattct ttaggaactt cttgcgtatt taacaaggtt ttcatacgct
    13081 cattcgttct tcgctcaata acttcaagct tttcatctat tgttccttta agaagttttt
    13141 taatatcatc tgcaatcatc atatttttac ttcctaacta gcaggttgac ctgtcacatt
    13201 gattgaagta gtgaattctc cagaagtaaa tgtgaatgtt gctgaccctt ctgctgcaat
    13261 cgttccatca aaaccaccat tttcattttt ggtcactgtt gcgatagctc catcacttga
    13321 agttgctgta gtagctgcaa caacagcagc tgcatcgcta gcatctgcag gcacagctga
    13381 aatagtaaat gttttagtat cgcctacttt accggtccat gtcttttgat ttggcacaat
    13441 accggtagca ggcgttacgc ttttggggaa atcttcccaa atgcttcatc ttttacaatc
    13501 ataaatccaa catccattgt tgcacgcaaa gcaatcagtt cttgctcaaa caagttaact
    13561 ggggttccat cttcattagt taaagtagac aattgggctt cttcagaaat cttaaatgaa
    13621 atattatatg ggatcccata aaacatgtaa ttaaagtctc cagcgtaaag tgttccttta
    13681 tctaaagact taaggtctac tactggtaat ccgtcaattg tattagtaga gcgatcataa
    13741 ataaactcaa catttgaccc gactgtttga gctgcagaac gtaattctgt acgatttttt
    13801 cggtttgaaa taaacgcatt aggttcgaat tcattttctg ctaacttgtc ttctaaggct
    13861 aggatattat cataagtcaa tccgccttca accacattcc ccgcactaat aactgatccg
    13921 tctagtgact gaggaaatgg gttttcttta tttaataagg cagctgcatc aaatttttta
    13981 tagaaagctt cagcaatttt tggctgcatc tcctcaaaga aatctgataa tttataattt
    14041 aaatattcac gagaaaccgg aagaatgaca ccgagttttt ttgcagtcat cgtagcttgc
    14101 atccatttag gtttagacgt tttaattttt tcaccttcac ccacccagta tgcgcctggt
    14161 ccttctgcaa agtattcaaa tttcttttct ttgtcagtca tttcttcgta ttttgctaac
    14221 tgcatgatct tagaattttc cataacttca ctcaaaatga gcgtattata tttatcagga
    14281 atttttccct ctttcgtttc atataccaag acattatctg gatcccatgt ttgagcaaac
    14341 atttgcaagt tcattggtaa aagttgtttc tttttcatta agttttcctc ctatttgata
    14401 attcgatttt tagcagctag tttagccact gtttctttag tatttttcga tgctgtaaat
    14461 tgtccacctt catttggtgg tgtttgtctt gcgttttctc tcttaatcaa agaagcaaag
    14521 ttagtgatga ctgctacagc ttgttttgtg gcatctgcat catcagaaac aatcagacca
    14581 agtaaatcat catcgtgtgg taaatttgca tctgtcagca ttttagaagc ttctttcgtc
    14641 atttcagata gtgcctgtcc acgctttaat tcagcgattt cagcttcttt ttgctccaac
    14701 tcatgctgta gtttttcttc cgcattcatt tttgccagct ttttagcttc ttcttttttt
    14761 gctgctagtt ctttttccca cgctgctttt gctttattcg tctcagcagc gatcattttc
    14821 gctacttcat cacgagaaaa tgttttgcca gtattgtttt cttcttttgc ttcgggcggt
    14881 gtctcttgtg agccagctgg taggtttcct tgttgtccct catcaccaga tccaccatct
    14941 cctggttcag aaaaaaattg taagttcatt ggcataaata aacgtttttt catgattaat
    15001 cctccacggt tacgccgcta cccgataaat ttgaccagtt acgccggtca gccgaaaata
    15061 gctttctctt taacgcctgt aagctgtaag aaggcacaat aaaaagccgt taatttgtgt
    15121 taacggcttg atattcgttc tatataaggt gctgtactgc atcgacaaaa tggatgcata
    15181 ttaggagcgt tacttcctgg ctgcatatcg gcaacatcaa aaacttgatt atttaacggt
    15241 atacatagtt tgcacgccgt tggttctgct atatagatgt actgggtaat gcctgcatct
    15301 ctataacttc gttcttgaat ccctacctga actctagtcg tttcagtcac catcaaacgt
    15361 tgagtgttga acttagtgtt ttctcgtcct tcagctgtta aatattctgc caatttagat
    15421 gcaagttgct tgggattttt ccccatcgtt atacttctga ctaacaacct atctaattct
    15481 gatttcaatt cagattgata catccataag cgatcactaa aagacacgtc atcactcaaa
    15541 aaggagctgt ttattactag ttctatcagc tttgcatatc cacttgaagc aatagtcatt
    15601 tctaaaatac cggcttgtct cttcaattca gctaaaccag cttttgttaa ttcattcgaa
    15661 aagtacttat ccaattcatt aaacagtgaa atcaattcaa gcccgatatt agcttttaag
    15721 agctctaatc tatttacacg catcgtaaga ttgtatagct ttaattcttg gtttgctgta
    15781 ggagaaaaat ctttctcttt gacatacttc tttgctttgc gagcgaatgc tttgacatcc
    15841 atttcactag cacgcttcat cgcttcgcta cgagtgattt tctggccatt ggagaaactg
    15901 tcccactgcg cgtctatttc tttttgtatc gcatcttgtg cgtattgcat gcgactttta
    15961 atttctgcca tgcgcttttt atcatcttta atttgttgct tttgccattc cttttcccgt
    16021 ttgatccaat attcttggga gttcatttaa tcacccccct gtttcatctt ttttgttgtt
    16081 aattacttct tcaccatctg aatcaaaaat gccaatctgc ttttgcgttt ctttatttac
    16141 tcgtttcaac tctgcctgta catctggaac aaaagaagcg agtcctaaga tcgtctcttg
    16201 actgagttca gctccagcat caaccaaaga tttcaactct tccagaatgg ctttaggtag
    16261 attaggcgta aatattacac gtaagccttt caaatcggag ttatccattt cagaaatact
    16321 tgattttagg ctaaataaaa gacgataacg ccgcataagg ccttttttga atagcctttg
    16381 ctttgttgcc gtcatttgtt caaatccaaa taatttatat ttcattgctt ctcccgattg
    16441 cactccggaa aaattgtcat cagtaagatc aggaaccatg gatatttcgt gaatatcctt
    16501 gcgtactctg tatttgtatg cttctacacc gttcacatca tattgtttgt aaatatatcc
    16561 tgcagtcaca cttgttttat taccgttcac atcagttcca gactcaagca aaagcatatt
    16621 cgcttctttc tgcttgatgg cgtcctctgt ggatagtcct gctgcttcaa tatcaccact
    16681 aataactaga agagcatcgt ttagatcagt catataattg gcggtatcag actgccctgc
    16741 atcgtataga tcaatcaaag atagtacatc ttcatacaag cccatccgaa aacgattagg
    16801 agaatactct gtaataggta cctctttata ttcatgcggt tcatcctggg gattctttaa
    16861 ctcaattgct gttagtgtcg tctcatcata agtgatactt ttttcttttg tgtatacgat
    16921 tggttgaatg tactgtttat cagcatcctt gttgaatctt gtcttaggat accgtacagc
    16981 caaaataggc tctcgtttta ctgtagtatc atatacaaca aacgtttcaa atacattagc
    17041 caaatcaaca taatctgtat catctgaatc tcgatagata atctcatagg ctctcccata
    17101 cttatccata tcaagccaga gttcagcatt taacccatct atgtcattat tagtattaaa
    17161 ctcttcgatt tctttttgtt gatttgtgtc ctcgatttgc acttttatag gattgcctgt
    17221 gttgtaccca acatcaaacg tacaaagaac ttttccaaag ttatgtgctg atcggtgatc
    17281 cgctttttct ttttctctgc gcctacggtt atccatgata tttgtatttc tagctttata
    17341 ataatcatct aatacactta gcctttttac ctgatattca tgatgatgtt ttatcattgc
    17401 tgctaaagta tctaaatcgt taagtaaatc ttctgctgag ctaaatctat agtgaagatt
    17461 tgagtctacg ctaaacttta cataatttgt gttcacgtca ttagaataat gtatatcagc
    17521 tccgtattca aactcgttta ccttatccat ttttcacact ccttaaaaca tgcgtttaat
    17581 acgtttaatc ttttcgttga cattaacttt tggtttctta agaagctcat gagtatatat
    17641 cgcatatcga acggagtcta gcacatcatc atattctttt attggctcgc cttttttctt
    17701 gtcccaaatg tattgataaa tttcatcccg aaatttcatc actctatctt gacagataaa
    17761 caatttatct tgtttaaatc tcttggcgac ttcctcaact ccagataacc gtgctttatg
    17821 agcattttta gcattaatct tttctcttac aaacctagcc acatgctccg gtctcgcaga
    17881 gtcacaataa aaaggtactc gtaagccgta acgctcttga atgccttttg ccacatctac
    17941 ccaataatca atctcttcaa attgagtagc atgttcttcg attaaataag ctgttccgtc
    18001 atccgtttca cctataacta cgattgaacc ccagtgttca tatccccagt caacaccaca
    18061 ataaaagttg ctcaaaggtg gtaagtcttt tgactggatg tagtgcttgc tagcatcaaa
    18121 atcacgataa acgacacctt ctgcagaaac ccataaacct ttgatatcac gatcataaaa
    18181 catgccgctt ggtgttgatt ctttaatatt gttacgatat cgttcagata aaaatgtatt
    18241 atcatctaat tcaaagtgga acgattgaat atttttgctt gaattgtcga tatactcttt
    18301 ctttagccag tgttccgggt tgtcagggtt tgtatcagct agtattctcg ctcctgttcc
    18361 tgaacaacgt gaaacgattt cagcaaatac ttcttgtcta gctagcgatg cctcattgat
    18421 ataagcgcca tatgctgtca taccacgaat tgcgccaaca ccgccaatgt ttcctgtata
    18481 agcttgtacg accttaacgc caaatagctt aaagtttcca tgtttatcga atttaggttc
    18541 tatgctgtac atgttgtata gttcctgtaa gatgttcttt tggattgttg cacttgaaac
    18601 tcctgctagg atatacattg gttccttaat gtcttcttca tcggcaatct ttcgcacacg
    18661 tcgcaattca aacaagaaca aatcattgtt tatttttgtt tttccagaac gttttgctcc
    18721 atgtaataaa gtaataaacc aatcattctt aatggtttta tttaacacgt cgatttgctt
    18781 tgggttataa atatcaacta gtgccatcta attcaccact aatcttttct aacaactcat
    18841 caagtttttc ttcggtagaa cgctctgagt ttatctgtaa ttgttctaat tttgcttgca
    18901 ttaattttat ttctgtttga gctttttcta attgcgtttg tgataacagc gatttatact
    18961 tcaaatacaa atccaaggct ttcaatttgc tttctaaatc tggtgtatat tcatattgca
    19021 tatgtttaat aaccttgttt ttctccaagc ggtctatttg cttgctcacg cttatttgta
    19081 cttctccttg ccaaatatct atcaattcat ttaaagcgtc ctcggcactt aatttgcgct
    19141 tcttttcgat aggatttagc cgttcattaa tatactgtat tatgttaggt ttagttaggt
    19201 tttccttacc tattactctt gctgatcgtt tgctataacc tgctttaatg gcggcttgag
    19261 tagcattacc accatttttt atatattcat ccgcaaaagc tttttgtttt ggtgtcaaat
    19321 ttaccacatt caagccacca cctttcaatt ttattaacaa tatctctcaa tatttgtctg
    19381 tatgttctgc tcactaaaat atccatggcc gcagtaacga agattgtact tatcaatctc
    19441 ttttggcgta gcttctctgg tcatttcaat gatggagtac ttctttttaa tctggactga
    19501 ctggacaact ctaattggat catctgcgtt tggttgcgga tatttatttg ataatgatac
    19561 ataccagtag ttcctcatta cgtatcactc tttctgttgg ttactggcag aaaaggttcg
    19621 catcataaat tccatagcct gtgcgtcatt aaatccttgc agaataagct gatcgtagaa
    19681 atacttagct tgttttgcga ttaacgctaa gcttttttga gtttcgtaga atgtcgcctc
    19741 cattgttttg tttgcttcat tcgttttaaa caactctctt aattggtttt cgttcatttt
    19801 tttactcccc ttccaaaata aaaagaccac tcgatgagtg atctaatatg taaaaactac
    19861 acctcataaa cgagatgcag ttatagttct atcaagcaac ctacaccgat tccatcgatt
    19921 actatcgacc tcgccttgct cgtgtacttt gagcgcccat ttccaaccct cagttgccaa
    19981 agtcactggc aaggaatcga accttgcatg gttgccgaag cattgaccta acacacatgc
    20041 ttagcgtcta ccctttccgc cacagtgaca aattaatatt gtgaaaataa atactaagtg
    20101 tataatttta tttatcagcg agtggtccgc tgaaataaat taaaaggtgg tgaaaaattt
    20161 gtactttgtt ataagagaag caactaatgg ccaatattac ttcgttatta agtccgataa
    20221 caatgaagta gtagcaacta gcgaaacata cttgactaaa tattccgctg aacaaaccat
    20281 taattctata aaaaacggaa tcaccaaaga ctctcaagtt atcgatgtga ctaaataaga
    20341 cgactaactt catttgctag ggagttcatt tcagctgctt tttctaccaa agcagttgag
    20401 atactttcta gcttttctga tttaacagaa ttaaatactg gcgtcttgat actaatcgat
    20461 acatcttgac gaggatcagg actcgttgct ctattttttt gcaccactga tctgtacttt
    20521 tctactgaat gatactcaat tacttgttct aaatgttttt tgtactcttt acatacagct
    20581 tctttttgga tcaattctaa acgttgttgc tcaataatat caatcaaccg ttcccgatcc
    20641 ataccttgat actttatttg ctcgacttcc attcgttttc cctccaatac ataaattaat
    20701 aaacagcaac ggatgataga taataagaac aatttagaag gagttggaat tcacatcctt
    20761 attcttaata tttccgttgc tgtctatcga agcttaattg tgaaacaata ataaaacgat
    20821 gttcctttta ttattatttt gtctcagacc tatcactaat ctttcgacac tatcataata
    20881 aatcatttac caggtaagtg attggtataa aaaaggtata aaatggaaac caaatgggta
    20941 atcaaagggt ataaaaagtg taaaaactgg ctacttaaaa gcaaccagtt ctaacgatga
    21001 agcaaattgg atgataattc tgtttgattc tactttaacc gattcttcgc tagtattatt
    21061 cctttgagca gttacataaa tgggcagacc attgatataa cgatcataga atatcttctt
    21121 gcgcctttct gttacatcag gtttatgcgg atgctgaatt gctgaatagc cacgaacaaa
    21181 taatttgtgc aagtactcaa attcttcttg cgcttcctct ctctcaatca tcattcgttc
    21241 tgcttcaaat gtattatttg ctgtagaagg tggaaccaag gagtaagatg ccgttacttt
    21301 aggctcccga ggttgaccta tcctacatct agctgacaga tatgctgaaa gaaaaacacc
    21361 aacattatgt tttgtgcgat ccatatccac atcttttgcc tctggtgtct catacttctt
    21421 tacatcgaaa agtaccatcc attgattcct ccatttatga tataataatt gtgtcagaat
    21481 tattaattaa ggtcggagga atccggcttt ttttataccc atgcttatgc taagcttttc
    21541 aagtagcgag gttgcactcg ttacccatat acatgttgag ctatctggcg gaaaacagat
    21601 ggctcactat ttcaatattc tgctaaggac agccagtggt cggctgtctt ttttatattt
    21661 taatgagaag ccttacttat ttttttatct ttattacgaa aaatgatatt atctattgat
    21721 aataaagcgt ataggagatg gttgagtgac tatgtggagc atgctgttat tttggattcc
    21781 cgtttgtatt ggtatcgtcg cattttgtta ctttgtcaaa cactctagaa caaataagct
    21841 cctcatgtta tcttttttac ctatagtatt ttttattgta caaattgtta aatataccta
    21901 tattgaatcg caagaaatat tcatttttta tgtggtaggt ttatttatct ctgtggtctt
    21961 tttcataatg atactttcct atttttataa aaaataaatt tttctcttag aagtacattt
    22021 tttcgctgtt tatatagcct tcatatccac caatctcgct acagctaaat tctctttgct
    22081 tttcgctaac cacttatcac attccatcgt gttttcaata cgaatgatcg ctgagtgatt
    22141 atagacgtgt tctacatatc cacgaaatgg atagatgaac ccttctgctt cgcagcgaac
    22201 catgtcaccg actttgaatt ttggtttctt acgtttttta ggattctttg tcggcatatc
    22261 tagcattaaa ccgccgatac catgactact agcgtaaaat ccgtctttta atttcatctt
    22321 tctacctcct catgatcgac agtgaccagt tcatatactt gtgttaatcc accaagtcgt
    22381 cgtgaaactt ggttagcttc ttcgaggcta tcaaaccatc tcgcactttg gagtatgtct
    22441 acaatgaata atgtgttagc ccctatagag cgttcatcac ttctataaaa tttattcccg
    22501 aactttacta cataaatctt cattctgctt cctcctcaat cgtccaagca tttgtaaatt
    22561 tctctaagct tattagttca tcttcattta aatatccgta accatataag gattctaaaa
    22621 ggtcttcttt tgaatagcct ctaaaatcaa gtctgagacc gcttaggatg tatacatagg
    22681 ttttatttcc ataaaacttg attgtgtatg ctttcatccc acttcctcct catcgatctc
    22741 tatctcgaca tctctgcctt ctaaaatctg tttggtatca atataggcta cgagtatttt
    22801 tcgattttgg cttaaagcaa tatacggatc aatcaaagca acttctgcgt gtagacgata
    22861 ataagcaata caatctattt ctaaaaatat caaacgatca atagcatcat taatcataaa
    22921 atctgtaacg ttttctgctg tatttaaacc atctgcatat ttaggcagga cttcattatt
    22981 gatgaactca gctacatgtt ttggacataa atcagtcagt tcttgttgtg tatagttcat
    23041 ttgctgtcct cctgattaat atatttcctc aaactacgta tccctttacc acgttttttt
    23101 gttttgcgct caatccacgt tcctgtagtt ccccagtagt caataattcc attatgggta
    23161 ttaattgcaa attgatgatt gtttggataa tgagtaaatt caaatcccaa ggtttcaata
    23221 tttttagttg ctgaattgcc catctttctg acatgttgtt ttctacgttc ttttagatgc
    23281 ggtttaatat ctttccagta ttcgcccata tcgcccattt cgctgtcctc ctatctcctt
    23341 gtccacaata aaaaccacat caactcttct gtcgtaccgt ttaaataaag atttatttct
    23401 gcaccaatcg caactaaaat tccgacaaca aacaaaataa tccctactgc tgtatatttt
    23461 ttgccttttg cactctcgta aatgaggtat gctcctaaca tcgctagtaa gccgccaatt
    23521 acacaccaaa atattgttag gctgatcatt tgctgtcctc caaatcactc gacttcacga
    23581 atacaccatc taccattttt cctgtgcgtc ctttgatttc gttgtatgct tggttcagac
    23641 actcgtacaa atccatatca ttttgcatag ctaaaataat caaggttact actacatctc
    23701 caattccgtc tcttaaacca tgttcatctt ttctagctag agaagcggca acttccccga
    23761 tctcttcgat cgtttttaac atttgcttgc tggaatcagc ttgatccaat cccttatctt
    23821 tagcccactg ctctactttt gtgattagtt cgtccattat tcattctcct ttatatattt
    23881 aagttggata atacaacttg taacaaatga agctaatgtt aaaattgtgc cgattggtgt
    23941 taaaaaaccg ctttttatcg cattaattaa tatagctaca aatatcgtta tatagaataa
    24001 aaagtgaatt gacgctaacg ttgaattaaa catctagtcc tcctcgaaat actcattcag
    24061 tatctctcta tacttttcta caaatttgaa acgatcctga tgaagtttct tgctccaatt
    24121 tgtttgccga tccagctcac gcatctgatc gaaccctttt tgaatttcgt tgtaataaaa
    24181 ttcaatgttt gctgctgctt tccaatgcct gctacttcgc actcctgctc ctgtttcagc
    24241 catttccaac ttaactaatt ccgctcgttc ttttgctttt ttatctttct gaatcttcat
    24301 catgattttc ttgaggatga tatcactgta ttgtgtaatg agatccatta tttctcctcc
    24361 acatacctaa actgtcgccc ctttgaatca atccataagc tcctagctct atcccagatg
    24421 atgtttttgc tcagtccagt aatttcagat aactgttcag ctgtacccgt tactagaatt
    24481 cgatcaccat gccagattgc aatttttctc ggcgttttcc gtttaggctt ttcagtccac
    24541 attgatttac cgagcttttg gacttctgca actatttctt tgtcttcttg ccaattctca
    24601 gaatgtgtca gttcaatgat tcgtttcatt gctgctttct tacccacgct cattcctcca
    24661 atctacgaat ttcccttctt aaattcacta tgtgcaaatt gattgccttt ctcgccgttt
    24721 cattgaccat cactgccttt atccgttcca gatcgtcaat ctcacgttga aggcttcgaa
    24781 tacgcatttg aatcacttct tctgttgtca tgatggacca cctcgttaaa aacgctcttc
    24841 cttgaacgta ttccgatatt ttttagctaa tatcaacggc acttgatatt gatgacagaa
    24901 caactttgcc ttgatcttaa agtcttttgt ctgcattcct ttgacatcta cgactttgac
    24961 aagtttgccg tttttataaa atgtgaagtc gggaatatac tcgatcttgc gatacttttt
    25021 tccatctagt tcaaatttcg gcatcagctc aaatctttcc tgaagtttta ctttccagcc
    25081 gttcgcttct gcttgccaca aggctaaatc gtaatactct gcttccgcga tagaatcaaa
    25141 cttgatacct cgatgaacag ttttcttatt acggtattta ttcatgcgat actacctttc
    25201 actggtttta tgcgcttgtc tgctgtttgt tggaatttca gcgcataacc ttctgaattc
    25261 ttaaatattc tagaaacaat tctttcgccg taggcttctc ttagttcagg accggataag
    25321 tttgttgtga tgatcgttgc cttgttctgt ctggcttcta agagcgtgtt taacgtgttg
    25381 tttgtaaact gcctactatt tgataccccg ctacctaatt cagctccaat atcgtcaaaa
    25441 accaccaaat cagttgtttt gatatcggct ataagcgatc cttcaatttc ttttctcagt
    25501 tcagcattgt tataagaaaa ctttatttgc tctaataact cttgatagct tataaaaagt
    25561 attttcttgt cataatttga gcgctcaagt atttcccaag ctgtcgccat tgacaagtgg
    25621 ctttttccgc ttcctgattt ccctgataga atgaaatgtg caggatggtt cagtaagaca
    25681 tcatttacaa agcttttagc tctttctaaa gcaattttcg tttcttggtc cactacgtga
    25741 taattctcca ttttgcattt aaacaaagtt ttatctgtta ataccgaacc attttgaaaa
    25801 aaactcaacg ctcgtgcttt taagctgtcg ttatatatcc gttcggtctg tatatcctct
    25861 ttcacacgta acgctttata accacaactc atgcatgttg gtttacaacg ttctgaacca
    25921 tccttatttt tagctcgcca actatacaaa ggttcgctac attctggaca tttcccgctt
    25981 tgcactaata ctcttcttat tagtttctcc atagcatttg ctaggctttc catgtgatgc
    26041 atctcctttt taaattggca agtcgtcata ttcactagga ttgctgtact gtagtttttg
    26101 actttgcttt ttatgattat tcttgtctgc tttgatttcg aatttgagct tctcaaattt
    26161 ttctctcaat ttcttagcac ttctaatatt tccaaaccaa aattcatttg taggtagcca
    26221 attgatcaca tactcaatcg cttctataga cgctttatct ctttcttcca tcaacctgat
    26281 tgtgtctgcc catttttcga tatctacttt gttcatttct tttggaaaat cttcagttaa
    26341 attactttgc aattttttag caaggcgtaa gtgttcgtca gaatacttac ctttcttttc
    26401 ttctttatct atatctatat ctttctctat ctctatctct aactctggtg tagttttgtc
    26461 tggacatttg tccgacactt gtcctccagt tattaaattc cgttttgcct cttctatttt
    26521 ctttctgtat tctctttttc tatctgcttc agttgaggat tttccaatga aactttgtat
    26581 atcagacata taaattgctc cgttatctaa tacgtcaata agctgcaaat cacggaaaat
    26641 ttgtaccgct ttttctacga ctcctacaga atgtcttgta atagttgcga gcattgtaga
    26701 gttaaatgga atcctgtcat taaacatcaa cttaccttcg tgttttagac ttcttaaata
    26761 aagtttgaga agaatattag aataaatata gccatctggc atactttcta agagaaccat
    26821 ctcgtcacta tcgaaaaaat tctcttttag ttttaaatag tagtagcgtt tgttgtcaga
    26881 caatattttt taccctccta ttctaagttt cttaattgtt tcctggttta acttgatccc
    26941 tttgatttga tatttatttt tgaaattgat cacacctata ttgtgtttct ccgtgtgatg
    27001 aatcctgcag agtgctgcaa atgtgtactc tgaatgatca acttctttgc gctttcgtct
    27061 tcctagcgct ttgtcaaagt gatcgatgtc agctcctgtt ttgccacaga tgcagcagac
    27121 tctttttgtg atgcatttgt agaagtaata ttcttgattc gctggtaaaa tctcatagcc
    27181 ttctttgaaa ggaatatgat gttcaaagat gaaatctaag atgatatttg ctaagacatt
    27241 agcatcactc acagttgtat tcgattcgtc tttgaggctt attttgcgcc ctgtgacgcc
    27301 ttcaaaacgg aagtaaaaga attccttcca gaagtccgtt ggcatgcctg tatcgatgaa
    27361 aatatcgcct atcagcgcat agatgaagtt tcgttgctgc acagtaaatc gacgtggatc
    27421 aataaatcga acttcaataa tccgatcgcc atcatatccg tcatacatcg tctttagtcg
    27481 atcaatgttc acttcttcat tgatcgttgc acctatgtct tttcctttga actttttcag
    27541 aaccgctgaa tatgaatcga tcaatggttt aaacactcat atcacttctc ttttgtttct
    27601 tctctgtact gatcttcaat ccagttaacg cctcgtttta gaatgcccaa gtctctcttg
    27661 gtccatttac tgtcatcagc ggttatagaa gccgcatcag tcaatgcaac aattgcttca
    27721 tcaattgatt tttcgtactt gttagcaacc agttgtaaag catccaagaa tagctttttg
    27781 cttctttgag tagctggttc aagcatcgag acatcttctg gcatatcttc gccagcaaat
    27841 atatatagcc ctagcccaaa cattgctaga ttttttacaa gacagcgcat gatcgttttg
    27901 ttgatatcaa acatagttgc tgcttcaact cgcttttcga tttttccaac aatctctttt
    27961 ttcttcgttt cgttattcca ctgataatca ttgacttcgt aggtatatgg ctcatctttc
    28021 attgccttgt ttgcaccatc catgactggt aaccacatgt cacgctttac tccgttgact
    28081 gtgatactgg taaaaaccat atagcctgtt ttcttatcaa agacatacgg cagatatgtt
    28141 tctggatcat gatagatttc ataatctact gcctcacaca ctttgctaac ttctgcccaa
    28201 gcccatgccc acgaaagata agtgaggtta tttcgttttt cagtaacatc tttcacattt
    28261 attttgtata aggtattaaa aagcgtatta tcacttctat ttttcaaagg ttgttccttt
    28321 tcactcatca aattctgcct ccatttcagc aatgtatttc ttacctgatc cgtaataaga
    28381 gatatcaatc aagttatctc tgtcatactc ttctagcgca tcaatcaagc catcttcgat
    28441 gacatagata tattcagttt ttttggactt cctcgataaa tggataagat agacatgatc
    28501 ccaaatactc acaaaatttc ccaaatcgtc ttgatcacat gctagttctt catccgtcaa
    28561 aagattacgt ctgatttttc gattgcttgt ttccttgata ttcgatttgc cccaactagg
    28621 atcagtcaaa tattgatcta gagtggaaag ttcttttttc atgtggtaac atctccttag
    28681 atgtattttc tttgtgactc attgctttgg tcggctgagt cactttttta tttgttgcca
    28741 tgctttttgc ttatcaatat gttgttggct taggatgttt ggtttattgt gtctccacca
    28801 gcgattagca attattacgc ctatttttag cgcttcagct ctattcatcc tctaacaact
    28861 ccatttgctt aataattgtc atcgtcgctg tagaaggcat ccaattgtta ataaaatcga
    28921 taacatcatc gaactgtttt gccttgatac gatttctagc tactgctcca gtgattcgct
    28981 taattccgcc attcaagtct ttaaacaatt ctgcttttgc tttgctattt aaatgctgct
    29041 gattacaaat aactctaatt ttgttgcgaa ccatattaga aattgttcgg taatctggtt
    29101 cagctagaag ttgattgttc ttcaaatcgt ttaaatcaga ctcgatagcg tctactcttt
    29161 cattcgtttc ttcgtttgca gctagagcaa gtaatgccat ttctcgttta gttgctggaa
    29221 ttgatggcaa ttggtctttt aattcttttt ccatcttgtt gaaggcctca atatattgaa
    29281 gtttaaaact taaagctttc ttaccagtga agcccattgc taatagagag aagccgtctc
    29341 tattcatata aataattcgg tatgattgtt tattttgagg atgaacataa gtatcttccc
    29401 aaaataggtc tgcccaattt tcggcaaccc cctcttttag ttcatcaata gccgtcaaaa
    29461 catgtctgtg ctttttatcg aagctttctg c
//
LOCUS       DAFLVO010000033        29097 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.033, whole genome shotgun sequence.
ACCESSION   DAFLVO010000033 DAFLVO010000000
VERSION     DAFLVO010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29097
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.033"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..1031)
                     /locus_tag="L1U99_001498"
     CDS             complement(<1..1031)
                     /locus_tag="L1U99_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1212045.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1113..1802)
                     /locus_tag="L1U99_001499"
     CDS             complement(1113..1802)
                     /locus_tag="L1U99_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBN1212046.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="L1U99_001500"
     CDS             complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="L1U99_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBN1212047.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2329..2832)
                     /locus_tag="L1U99_001501"
     CDS             complement(2329..2832)
                     /locus_tag="L1U99_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBN1212048.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3036..3163)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="L1U99_001502"
     CDS             complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="L1U99_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBN1212049.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="L1U99_001503"
     CDS             complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="L1U99_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBN1212050.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4800..5468
                     /gene="sdaAB"
                     /locus_tag="L1U99_001504"
     CDS             4800..5468
                     /gene="sdaAB"
                     /locus_tag="L1U99_001504"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HBN1212051.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5481..6353
                     /gene="sdaAA"
                     /locus_tag="L1U99_001505"
     CDS             5481..6353
                     /gene="sdaAA"
                     /locus_tag="L1U99_001505"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HBN1212052.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6444..7463)
                     /locus_tag="L1U99_001506"
     CDS             complement(6444..7463)
                     /locus_tag="L1U99_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBN1212053.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7636..8541)
                     /locus_tag="L1U99_001507"
     CDS             complement(7636..8541)
                     /locus_tag="L1U99_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBN1212054.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="L1U99_001508"
     CDS             complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="L1U99_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HBN1212055.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9246..9416)
                     /gene="secE"
                     /locus_tag="L1U99_001509"
     CDS             complement(9246..9416)
                     /gene="secE"
                     /locus_tag="L1U99_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBN1212056.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="L1U99_001510"
     CDS             complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="L1U99_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBN1212057.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9754..10398
                     /locus_tag="L1U99_001511"
     CDS             9754..10398
                     /locus_tag="L1U99_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBN1212058.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10454..10957)
                     /locus_tag="L1U99_001512"
     CDS             complement(10454..10957)
                     /locus_tag="L1U99_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBN1212059.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10970..11016)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11554..12519
                     /locus_tag="L1U99_001513"
     CDS             11554..12519
                     /locus_tag="L1U99_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBN1212060.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12618..13790)
                     /locus_tag="L1U99_001514"
     CDS             complement(12618..13790)
                     /locus_tag="L1U99_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1212061.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13777..14922)
                     /locus_tag="L1U99_001515"
     CDS             complement(13777..14922)
                     /locus_tag="L1U99_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1212062.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14936..15868)
                     /locus_tag="L1U99_001516"
     CDS             complement(14936..15868)
                     /locus_tag="L1U99_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1212063.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15985..17064
                     /locus_tag="L1U99_001517"
     CDS             15985..17064
                     /locus_tag="L1U99_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBN1212064.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17061..17679
                     /locus_tag="L1U99_001518"
                     /pseudo
     CDS             17061..17679
                     /locus_tag="L1U99_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(17789..18016)
                     /locus_tag="L1U99_001519"
     CDS             complement(17789..18016)
                     /locus_tag="L1U99_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBN1212065.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18119..20707)
                     /locus_tag="L1U99_001520"
     CDS             complement(18119..20707)
                     /locus_tag="L1U99_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBN1212066.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20727..21386)
                     /locus_tag="L1U99_001521"
     CDS             complement(20727..21386)
                     /locus_tag="L1U99_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBN1212067.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21435..21938)
                     /gene="trmL"
                     /locus_tag="L1U99_001522"
     CDS             complement(21435..21938)
                     /gene="trmL"
                     /locus_tag="L1U99_001522"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBN1212068.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22159..23025)
                     /locus_tag="L1U99_001523"
     CDS             complement(22159..23025)
                     /locus_tag="L1U99_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBN1212069.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23134..23775
                     /locus_tag="L1U99_001524"
     CDS             23134..23775
                     /locus_tag="L1U99_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBN1212070.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23837..25198)
                     /gene="mgtE"
                     /locus_tag="L1U99_001525"
     CDS             complement(23837..25198)
                     /gene="mgtE"
                     /locus_tag="L1U99_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBN1212071.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25216..26115)
                     /locus_tag="L1U99_001526"
     CDS             complement(25216..26115)
                     /locus_tag="L1U99_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBN1212072.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26117..26914)
                     /locus_tag="L1U99_001527"
     CDS             complement(26117..26914)
                     /locus_tag="L1U99_001527"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HBN1212073.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26892..27596)
                     /locus_tag="L1U99_001528"
     CDS             complement(26892..27596)
                     /locus_tag="L1U99_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBN1212074.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27727..28302
                     /locus_tag="L1U99_001529"
     CDS             27727..28302
                     /locus_tag="L1U99_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HBN1212075.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28420..29097
                     /locus_tag="L1U99_001530"
     CDS             28420..29097
                     /locus_tag="L1U99_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBN1212076.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8560 a         6167 c         5232 g         9138 t
ORIGIN      
        1 aatacagtat tatttcggtt gcttgctgct tcacctagcc cttgtactcg tgtttgattg
       61 gcgacttgac caaattgatt cccgacgtct aataaaataa tagctaaaag caaaatggcc
      121 aaatggcttc cgccaaccaa taaagcaata aagcttattg tttgcataac aagtcccata
      181 tacacgattt ttctttcaga ataagaatct gccagtcgtc ccacgatagg tgcagcaact
      241 gctccagaca aaccaaaaat cgctaatatc cctgcttcga atgttcccca attgtaggcg
      301 ggactgctga tataaaaaat caacgtagac caaaagatcg aaaatgttcc aaacatgaaa
      361 aatccactga ctgccgcttc tcttaataga cgttgagaag caactaaatg cggcaaactt
      421 ttaagtgaat caaggtatga aacagctgta ctactttgct ggacagaacg cggcattttc
      481 cagtaaagca gaagtgtaag aattccgact gcacataaag caaataaata gatcatccgc
      541 caagaaaaaa gactggcaac aataccagat accgtccgag aaagcaaaat ccccacgagt
      601 aaaccgctaa gcaatgtacc catgaccttc cctcttgctt ttggtcccgc tagtaccgca
      661 ccgtaaggaa tgatgatttg cggcacgatc gaaagtaatc ctattaaaaa agaagcgcat
      721 gcaaataacg taaacgaagg cgcaaaaaaa gcggccaaca gagagacggc agataacgct
      781 accattcgaa tgatcaattt tggacgatcc accacgtccc ctaaaggaac taaaaacagt
      841 aaccctaacg catagcctaa ttgggtcaac atcgtcaata tcccgactgc acttgtgcta
      901 acagataaac tagctgctac ttttgttcca atcggctgga tgtaatacat attggcaaca
      961 acaacgccac aagtgattga taatagtaaa ataagcgaag ttgttaaagg tgttttttca
     1021 ttactcttca ttgatttccc ccatttccta tcttagttta caacttatgg aaaagattgg
     1081 aaatagaaaa atacaactat tcgccacact tattatttgt gcttttgttt tccttgtttt
     1141 ttcttgcgat ctttataaat gaagacaact aaccctacta gcacagtaac acttgcaacc
     1201 aacgtgactg cagttttgtt atatccgtga aacagagctt ctccaccaca cgcatacaac
     1261 acagacgaag ggatgactcc aatcacgatc gacaatatga tttgctgtag aggcaatttc
     1321 atcgcatctg cagcaaaatt gaccatagaa gatggaataa ccggtatcat atagcctaac
     1381 attacaccta tttttggatg tttcatttgt cggattgctt gcacccaatg attcgtttcg
     1441 gttttcttat ctaaaaattt taagcgatgc ataaggaaaa ttgcagtgat gttaccaaga
     1501 gcattaccca aaatgttgat gatcgcacct gtcagtggtc caaagctcaa accagcaatg
     1561 actccaacta ctgaagtagg aatacctgga acagcacaca tcaccgctgt caatacgatc
     1621 aagagtatcg atgcaaaagt cccatgcgaa cgaatatgtg cgagtagctc tgccttactc
     1681 gctctcggat ttaaaaataa ttggatgtct gtctgatatt ctaaatacaa ccgatagccc
     1741 actaccagta tcagaatgat tcccaacgag atcaacatca atcggattat tttctttttc
     1801 atatttcctc ctgaaaaaaa tctatattca ttaaataata gtttaacata aaaacaaaaa
     1861 agcaccgaaa tccaacatag gatctcagtg cttttaaata gtaaaaatta tttaacagtt
     1921 acagatgcgc caacttcttc aagtttagct ttcaattctt cagcttcttc tttagatacg
     1981 ccttctttaa ctggtgcagg agcgccatca actacagctt tagcttcttt caagcctaaa
     2041 ccagttgctt cacgaactgc tttgataact ttaacttttt ggtctccagc tgcagttaat
     2101 tctacagtga attctgtttg ttcttcagca gcagcagcgc caccagcagc agctacagct
     2161 acaggagcag cagcagatac gccaaattct tcttcaatag ctttaactag gtcgttaagt
     2221 tctaggatag ttgcttcttt taactcagca acgatgtttt caatgttcaa tgccattata
     2281 atttcctccg tttaattgtt cttttttatt taatgcttta tgcggcaatt aagctgcatc
     2341 tccatcttct ttgtctgcca ctgctttgac agcgtaagcc acgttgcgga ctggcgcttg
     2401 tagtacagat agcaacatag atagaagtcc ttcgcgattt ggcaattttg ccaatgctgt
     2461 gatttcttcc aatgaagaga ctttaccttc gatgataccg cctttgattt ctaatgcttt
     2521 tgcttcttta gcaaattcgt ccatgatttt cgctggtgcg actacatctt cgttactgaa
     2581 tgcaacagct gtaggtccag tgaatacttc gtccatgcct tcaaggccag cttttttagc
     2641 tgcacgtgaa agaatagaat ttttgataac tttcatttct acgttagcat cacgaagttg
     2701 tttacgtaaa cgtgttactt catcaactgt taatccgcgg tagtcaacga ctactactga
     2761 tgcagctgct gtaaattttt cgcttacttc atcaacgatt gctgcttttt ttgcgataat
     2821 tgcttcactc atttttgagt ttcacctcct gaattttgat ggaagagttt tttgcactga
     2881 aaaggcaagt cacttttata gttactttgc tcaaccagta ttattcatca cctattcact
     2941 tcgttcatag tgattctact cgctttgctc gaaaggaaac tcctttcgct ttgctcaacc
     3001 agtattgttc atcatctctt cacttcgttc atagtgattc acaataaaaa actctatgcc
     3061 accgcagaca tagagggact attgaatata ttcaataaac gtcctcggta ggaaattaag
     3121 gcttgatgcc acctactgtc ttcggtacaa gttaattatt aacctcaact agcttagcat
     3181 gctaaactag ttgagtcaag aattattttt cagttggatc aatcaacatt ctaatattta
     3241 attagaaaga agcttggtca acatggatac caggtccaaa tgttgttgtg atcgttacat
     3301 ttttcatgta ttgaccttta gctgctgatg gtttagcttt tagcaataca tcatggattg
     3361 ctgcaaagtt ttcaactaat ttttcatcgt caaatgaaac ttttccgatt ggtacatgga
     3421 tatttccagc tttgtccaca cggtaagtta ctttaccagc tttcacttcg tttactgctt
     3481 ttgttacgtc cattgtaact gtaccagttt tagggtttgg cattaagcct tttggtccta
     3541 atactcgtcc tagacgacct acagtagcca tcatatcagg tgttgcaaca actacatcaa
     3601 agtcaaacca tccgttttgg attttttgaa ccatgtcgtc gtcacctacg aaatctgcac
     3661 cagctgcttc agcttctttt gctttgtctc ctttagcaaa aactaaaaca gtttgtgttt
     3721 taccagttcc gtttggtaat acaacagcac cacggatttg ttggtctgct tttttagggt
     3781 ctacgttcaa acggtatgca acttcaactg ttgcatcaaa ttttgcaatg tttgtttctt
     3841 ttgctaaagc tactgcttcg gcaacaggat aaactttact tgaatcaact ttttttaatg
     3901 catcttgcat ttttttgctc tttttagcca ttttggttcc tccttgattg tggttataac
     3961 ggttgtacct cccacgtgtt ctatatcttt caatatagag ccaactgaga agctgctgtc
     4021 ttagggtgta tagattattc tacagtgatc cccatgcttc gtgcagttcc ttcaaccatg
     4081 cgcattgctg cttcaacgtt agctgcgttt aggtcttcca tttttaattc agcgatttct
     4141 cttacttgat cgctagaaac tttcgcaact ttatttttgt ttggttcgcc tgaacctttt
     4201 tcgattttag ctgctttttt caatagaaca gcagctggcg gtgtttttgt aacgaatgtg
     4261 aatgaacggt cttcgtatac agaaataaca accggaatga tcaaacctgc ttgatcagct
     4321 gtacgagcgt tgaattcttt tgtgaatccc atgatattga tacccgcttg acctagtgca
     4381 ggacctactg gtggagctgg agttgcttta cctgcaggaa tttgcaattt aacgattttt
     4441 tctactttct ttgccacgag acatacctcc ttaagtccgt gatgtggtta attggagatg
     4501 catatttctc ctcccacgtt ttatctgatc tgaaaaaatc cagacaaata atgtgcaaaa
     4561 caatgcacac tggtacagta tagcaaattt atttgttttt tcaagatttt tttctgctat
     4621 ttttacattt tgcttgaata aacgctaaat ttattctaaa aaaacaacaa tttttcgttc
     4681 tcatttcttc ttttatgtta cacttgcgct agcatggttc aacagatgaa agcaaacaat
     4741 aacacggttt tttagaccct tgtacaaaga ttcctacata acaaaatgag gtggagaaaa
     4801 tgaaagattt aaggtataga agtgtctttg atattattgg acctgtgatg attggtccaa
     4861 gtagctctca cactgccgga gctgctagaa tcgggaaaat catacgtagt atatttggcg
     4921 aacagcctga ttctgtagat atttatctat atgaatcatt tgcaaaaacc tatcgggggc
     4981 acggaacaga tattgcatta gttggcggcc tgttagggat ggaacccgat gatgaacgtt
     5041 tagctgattc tttgaaattg gcatatgaag ccggtatgga agtcttgttt gttcctaaga
     5101 gtgaaaaagc cgaacatcca aactctgtaa agatgcttct aaaaaaagga acacgaaagc
     5161 tttcagtcac tggcatttcg atcggcggtg gcaatatcca gatttctgaa ttgaatggat
     5221 tcaaaatttc tttaagcatg ggtactccta ccttgatcgt tgtccaccaa gatgttccag
     5281 gtatgattgc taaagtgact agtatacttt ctgagaccaa tacgaatatc ggcactatga
     5341 cagtgacacg ggaatcaaaa ggtgaaaatg ccattatgat aattgaagta gatgatcctc
     5401 aagtagaaga aacggtaaaa agactcaaac agctgccaaa tatcgacagc gtaaattatt
     5461 tcgattaagg agctaaaaaa atgtttttat cgattgaaga attagtagat caagcaaaag
     5521 cttatccaag tgtagcagaa ttgatgattg cagttgaaat ggaaatgagt ggccgttccc
     5581 gtagtcacat catcgagatc atggaaaaaa acctctcagt aatggaacaa tcaatcaacg
     5641 agggaaaaga aggtgttacc tccgtcacag gaattaccgg tggtgatgca aaaaaattag
     5701 atgattattt aaatgaggca gactttttaa gtggagaaac aatcttaaaa gctgtacgca
     5761 atgctgtagc tgttaatgaa gtcaatgcaa aaatggggtt gatttgtgct acaccgactg
     5821 ccggaagcgc gggtgttgtt cctggtgtgc tgatggctgt ccgagatcgg cttgatttga
     5881 cacatgaaca gcaattggaa ttcttattta ccgctggcgc tttcgggtta gtcatcgcaa
     5941 acaacgcttc tatcagtggt gcagaagggg gatgtcaagc agaagttggt tctgcaagtg
     6001 caatggcagc agcagctttg gtttgtgcaa aaaatgggac tcctcatcaa gcagcacaag
     6061 cagtagccat tacattgaaa aatatgatgg gactgatttg cgatcccgtt gcaggcttag
     6121 ttgaagtccc gtgtgtcaaa cgtaatgctt taggctcttc tcaagctttt atctctgctg
     6181 atatggcatt agcgggtatc gaaagtgtca ttccgccgga tgaagtcgtt gctgcaatgt
     6241 accaagtcgg acgtcaaatg ccgtcgattt tcaaagaaac agcagaaggt ggcttagctg
     6301 ttacgccaac tgctaaacga cttgcggaag agattttaaa taagagggcg tgataaagct
     6361 ccttaatttc gagtattaag agattagtta tcttcataac aaaaaacgaa gagaggacta
     6421 attgcccttc tcttcgtttt ttattaatcc atcaatttcg tattttttac ttcatcgatc
     6481 gtttttgttc ctgcaagttg catcgtgatc gacaattctt tgttcaggtg ttcaaaaaca
     6541 gatgttactc cttctgcccc acctagattc aacccataaa tcactggtcg gccaatcgca
     6601 actaagtcag caccacttgc cagagctttg aagacatgct ctcctcgacg gacaccagag
     6661 tcgaaaatca ctggtacacg tttgttgact acttcggcaa tttttggcaa tacttcaaag
     6721 gacgcaggac ctccatctag ttgacgtcca ccatgattgg atacccagat accatctgcc
     6781 cctgcagaga tagcgattac tgcatcttct ggcgattgta ttccttttac gataactgga
     6841 agatgggtga tttctttgat tgttttgatg tcatctggtg tcaagccttg ttttgcagct
     6901 gcataaattt ctgcgattcc ttttccttcg ccattaccac ttgcactttg ttcgctatac
     6961 gcagctaagt taggcattgg taatggaaat tggaattgat tgatgacgtc ttcttcacgg
     7021 taaccaccga gcgttgaatc tgccgttaaa atgatagctt tagcccctgc ttctactgct
     7081 ttgttcaaaa tgaactcatt gaatctgtcg tctttactca tatataattg gaaaaactgc
     7141 ggtgcgcctg gcgctgcatc ggctgcgtct ttgattgtcg tatttgcata agtgctgatg
     7201 gaaaagattg atccagcagc agctactcct ttagctgtat cagcttcccc tttttcatgt
     7261 gccaatcctt gggccgctga tggcgcttgg ataatcggtg tatctaattc aattccgaaa
     7321 acagatgtat gcaaatcggc tgagtcgatt ccgcgtaata tccgtggcat gattttcttt
     7381 gtattaaaag aagtcgtatt ttctttcatc gtccactcat cttcagaacc accgcgaata
     7441 tagccaaaag ctcctgcttc catgcgctct tttacacgac cttctagtta ggcaatgttt
     7501 acaatatcga ttggatgttc ttcattactt gtatgataag tcatagtaga tccttctttc
     7561 atcttcttga ttacatataa atcatactaa acttacaaaa agtaagcaaa catttactct
     7621 cagatacttt tatcgctatt ctttccaaat aaatcgactt acaagctgat ctacttcttg
     7681 gttttcatga agcatactat gagaggcatt ttcacctgtc actacttttt cctctatttc
     7741 atttccgcgt tgcttcaaca acgcatagac cgctaatgca ctgtttaacg gtactgttcc
     7801 atcactcaag tctgtttcat ctagttgacc agcaatcaag aaaaatcgag tggttatagg
     7861 aatattaccg atcatttgct ggtaatcttg atagcggtta gaaacgacag caggcccctt
     7921 tgctaactca tctgtcagag actgcgcact atcatcgaca aaatcattaa aaggcgcgcc
     7981 aattgctgtt aatgtctgaa cttgtggcaa tgacgtatcc tgtccatacg ttcctaaata
     8041 gcgtagtgca ctaactcctc ccatggaatg ccccactatg ttgactttat ctatgccgta
     8101 gttttctttc agatacaaaa gacaagtttt gatccattct gcttgattcc actcgttatt
     8161 tttattatct tcaaacaata cttggaccat cggattgtct gcttttccag acaaatctcc
     8221 tgttgcttgt atttgtccat ctgttcctac tgttaaaacc aattctttta ctgcttgctg
     8281 atttttttcc aaacgccgca acatcccttt aaaggaattt tctgtcccgc tgtagccgtg
     8341 gaaaaaaagt gttggaatag tggttttttc tatcacttta ctggattctg ccgttttttc
     8401 tttatcagaa acttcagtag tatttatctt cgtcgtctgg caaccactta acgcaaacaa
     8461 actgataagg actaaagctg ctgcagttgc acgtttgcat aaatttttga ttggttctgt
     8521 catacacctc ttcctttcca tatagaaaaa agaaagactt gaaaggccaa tcatatgatc
     8581 gacatttcaa gtctctttat taatcgattt tatctacttg atcgaaatca agttctgtac
     8641 tggtttcacg tccaaacata tcgatgttga ctttcaattt ttctttttct ccgtcaactt
     8701 ctgttacttg tccttctaat ccagcaaatg cgccttcgat gattttcacg acttcgccaa
     8761 cttctacttc tagatcattt tgtcgcaggc tcataccgat agaacgcaag atatgattga
     8821 cttcttctgg aagtaatggt gctggtttgc ttccggctcc gtgtgaacca acgaatcctg
     8881 tcacaccagg tgtgttgcgg acaacatacc atgaagcgtc tgtcatgatc atttcaacaa
     8941 gtacgtatcc tgggaatgtt ttatgaacga tttctttttc tttcccattt ttgacttcag
     9001 tttctttttc ttcaggaaca acgacacgga aaataaagtc ggccattttc atactttgcg
     9061 cacgagattc gatatttgct tttactttgt tttcatatcc tgaatatgta tgcaagacat
     9121 accagttttt ttcaaaagat tccattgaag gctcctcatt tcattgtaaa ataaaaaaac
     9181 ctcagtacac ccgaagtttt tctttcgctt cattatagca ctaaaagtac gttgtggcta
     9241 gcgagttatt ttaaaatcca gccaaataag ctttggatgg ctgtatccat tacgtaaaac
     9301 atcaatccga aaataataga agtttcgatg actactaacg tatctttacg gagttgtttt
     9361 ctgcttggcc aagttacttg tttgatttca tcttttacgc tttttagaaa tttcatgaga
     9421 caacctccct tgctactgtt tatttcgttt ctttatgtaa tgtatattga ttacaatatt
     9481 tacaaaactt attgatttcc aaacgttcgc cgctttttcc ttcactgact gattttgtgt
     9541 agttgcgaga cccacaaacg gaacaagcga gtgctgcttt tttctttgcc atttacttct
     9601 gcccccttgc tgagaatcag acttatactt cataacagta tcacgtaact ttttacttgt
     9661 caatttgtga aataaactat ctattgtttt ggataaaatt atgatatgat taatttgaaa
     9721 ttaagctaaa atgagacaat tggaggtata gcgatgctat taaaaacact tgtatataag
     9781 aaaaaagatc tgacaaccgt tacagagact agtacattag aagaagcatt aaaaatttta
     9841 gaaacttccg gataccgttg tgtgccgatc ttagattctt caggtaatat tttccgtgga
     9901 aacatttaca aaatgcatat ctatcgtcat aaagcaaatg gcggtgatat gacgcttcct
     9961 gtcactcatc ttttgaaaaa cgctacaaag ttcatttacc tggatacttc tttcttcaaa
    10021 gtattcttta cgatcaaaga gcttccttat attgctgtcc ttgacagtga aaatcatttt
    10081 tatggtattt tgacacatag tacgttgctt aatatgctct ctcaatcttg gagcgtagaa
    10141 caaggaagct atgtactgac aattgcttcc acaggaaagc aaggagattt ggctgctatt
    10201 gcaaaaatca tttcaaaaca cagcagcatt gccagctgta ttactcttga tatcgaaaaa
    10261 gacgaataca ttcgacgtac attgatcacg ctaccggcta acactgaagc gaaagtatgt
    10321 gaaacgatcg tcaaccactt agagaaaaag aattataaag tggtagaaat tgaaaatttg
    10381 caaaaccaag aagcataatc aaaaagcgaa aaaagaaaac agctaatctg ctttcttttt
    10441 tcgcttttta taattagaca cgcttttcaa aatcaagcgc gcgatctaaa taatacatca
    10501 atggtgctga aacagccatg acgataaact cacttaatgc aagcgtgcca taggttgtcc
    10561 aaaatgcttg gccacctgtt ggaactaaca tataagcaat cagtcccatg ctgatggtaa
    10621 agaagatcgt gttcaatact aaacgcatct ttacattttt cactttgttt tgcaataaag
    10681 ctgtcaggcc taaagaaagc aatgtttggc cgccaccaaa aaccacatcc atgataccaa
    10741 aaccaaagaa ggcattatag acgatgaccc cgcctaaaac tccccaaagc aatttacggt
    10801 taaagacaac taaatgattc aaactttctg aaatacgaaa ctggatcggc cctgaggata
    10861 caggcgcaac taaaatagtt aacgctagat aaagagccat gatgatgcca tttacaacga
    10921 ttacggataa ccgttgtctg cttttcgttt tttgcatttt ctctcctctt ttctcctagt
    10981 ttttttaacg cgggatggtt gatgaaccgc ggttatgtga aacaaacaat aattataaca
    11041 gacttttcat ttatttcaat ccgtcttatc tgcttttaaa aaagcaaaag cttaaacaat
    11101 gtaaacgttt gctaaaaatc gtgggatatg gtataaagta agtgtaaggg gtcataagaa
    11161 ttcccagtaa agcagacgaa gtaggatctg caagaacaga attgttgtga aacttaaata
    11221 aataaaaaag gatgtgggaa tttgagcaac ctcttactag agaacggtct agcaagcagc
    11281 tgaagatcta agtggacatg ccgaaccttg gaacttctcc ttacgtaagt aatggatcat
    11341 gcgcttgcta ggcttttttg tgtttttcgg tcttcggacc tttttcattt tcctagactt
    11401 ctgctataat aaccaagaat taattttgta acagattttt ttgaaaaaac aagtttcttt
    11461 cattcaaaaa atagaaaaag cttgctaatt attggttaac cagcaaacag gagtattaaa
    11521 atatcttgtt ttattgaata gcaggaggaa atcatgaaat tccattatca tatattgatc
    11581 aatccatcgg caggcagcgg aaatggctat aaagtagcag aaagaatttt accggtatta
    11641 aaaaataagc atattgacta tacacttcat tatagtgaat acaaaggaca cgatgctgag
    11701 attgctgaaa ctttggcaaa agaaacattg attccttgga tagaagaaga acagaaaaca
    11761 atcgatactt tccccctttt gatcatcgta ggaggtgacg gcaccttaca tcaggtactt
    11821 gatactttct atcagatgga agtagaattc ccagttgctt atattccagc aggttctgga
    11881 aatgattttg ctcgaggggc aggccttcca aaaaatccca aaaaaggact tcagctgatt
    11941 ttagcagctc aatcaccaga aaaagtccac ataatggctt atgaagaaaa aataagtgaa
    12001 aaaaaaggaa tagctgttaa taatttcggt ataggattag atgcagctat cgtccatgcg
    12061 acaaatcatt cttccacaaa aaagcgattg aacaaataca acttaggatc attttcgtat
    12121 ttattctcta ttctccgtgc tttattcact caaaaaggat ttccaattct ggtagatgca
    12181 ggaggaaaac aattaagttt ttcaaacgca tttttatgta cagcaacgaa gcatcctttt
    12241 tttggcggag gaatcgcgat tgttccaact gctgatgcgt ctaaaccagt cattgatttt
    12301 gtcgtggtcg aacgaatcaa tttctttaaa atcttgtggc tcattctttt acttatacag
    12361 aaaaaacaat tgaaatcgaa atatttccat cactacacaa caaacagatt acgtatcgtt
    12421 tcaacaacac cgcaacatgg tcaagaagat ggagaagaaa tggaaaaacg accttttgat
    12481 atcacaataa ccacaactaa acagttgttt tggtgttaat aaaagaggtt ttgtcagaag
    12541 ctacatctgg aacaccgttt attcggaaaa aaggactgtg acacgacttt tgtcacagtc
    12601 ctttttttac tatgcagtta attctttgcc caattgggtt gccatcgata gtttctttct
    12661 ttacccaaaa taaattggat cattgaaaac accgcagcaa aagcaactaa gacacaacca
    12721 ttgaaccaaa aagattctgc aaatgtttga ttgtaactga gtgtttcact gatcaagtta
    12781 ttattttgaa caaaccaata tgttggtgtg aatgccgcta ttttgctaac catttctggc
    12841 aagtattctg ctggtacaaa caccccaccg ataaagcaac tgcctgtgat aaaaatatct
    12901 ttgatcccac cgctggtttc tgagtttttt accaatgaag tgatacaagc cgaaaagcta
    12961 atgatcggca ataaaaacaa gaaagtattt aaaatatgat accataccgt tatatcccac
    13021 gaggtgtgga tcactaacag aaccattaga agtaagaagc cactgaacaa cagcagcgag
    13081 taactaatca aactaaaggt tactttgcga ttcaagtttc gtttggtaat gggcgcactc
    13141 tggtttcgtt tactgatctc tttgcgatta aacgctagat tgatgacgct gaaaccgcta
    13201 aaaatggata gaaacaaccc ataagacaag aaattaaagg ttgtgcccgt caacagcttt
    13261 ttcatccgct gactatatcc cgcacttagc tcaacttctc cagtaaccga gagtgccatt
    13321 tgtgtctgtt ccatagctgc atcgattgtt ttatcttctt cttgaaacag aatcagtgtt
    13381 tgcaaaaagg tgttcacttg ctgtgtaaca actgttttag aaaaggcatc tgggcgactc
    13441 tgtatcttga tcgtcgccat ctttcctact tcgacttgtt cggtaaagtc tgcaggcaga
    13501 tgtaagataa tgtttacacg attaaaataa agagcatcat cgatttcttt ttgtgaggtt
    13561 ccatccaatg taacgactgt ttccttgtca ttcaaatatt tacgaaggcc atcgactaca
    13621 ggcgactctt cttcactaat caaggcgatt ttcgcatctt gcagagaggt attttcaaca
    13681 tcaatatttt gcgcaaaaaa gaatgtggca acaacagtga taattacacc tatcagtaaa
    13741 ttcgatttat ttgctttaag caatgtccaa atcgttttat aaagcgtcat aacgcacccc
    13801 tctttccatc caagcatttc ctaacgcaaa aaggaaaata aatccgatca accatagaag
    13861 attggtataa aaactagcca aatcagtgta gaaataaagt ttatacaaac tttcgctgat
    13921 caagttgacg agatttaatt gaccaacaat cggaatatga agatcaatcc aatacttcac
    13981 ttgttccgac cccatcatac cagcaaaaaa gctcatcgca atcgtcactg aaatcaagat
    14041 gctatccttt tgcaccagat tcatttttgg tatcaaatta ccaaccaatg tacctaacaa
    14101 aatcgcacac aacgacccca gagcggtaac aatcatcaac cattgccaac gttcaccaaa
    14161 gtctacttga tagataaaac gaaagacagc taacataata taaatctctg tcaaaacaat
    14221 cgtaaagctt gctgccaaat tagcgattga aactaacgat tgctttctag gaatcaagga
    14281 caagcgaata ccatttgacg attgatttgc ttgctgatcc tgtacattgc ggacccccca
    14341 catcgtcccg tagagaatcg ccattccaat cagagtgaag aaataaaaac ttttgaaact
    14401 catattacga cctgcatgaa cttcttgaaa agatacttct tgttcaaaaa cagtcatgat
    14461 gggcgcgaga tcaacgttct ccacttctgc cactttactc gaaattatac caatacgctg
    14521 taaaaattga tccatgacgt ttttcatcaa cgtctgactc attcctgctt gacccacatg
    14581 gagcgaaaca gatgaaccat caatgagata aaaaccagcc aaatcatctg catttagctt
    14641 ttcattcgct tctacttccg atagttcctg tacttcaaat aatggtttat cattgacttc
    14701 gacttgttct aagactgtgg taaaattttc cgaaagcgct gtttgatccg ctttgattac
    14761 aattccagta ttaatcgttt caagattgcc accttgatca atctcgccaa aggccgccat
    14821 aaacatcaat cctaaaagaa ttggaaaggc caatgtccaa aacaacatgg atttatttcg
    14881 cagcagtatt tttgtgcgat atttataaaa atgccaaaac attatttccc ctcctctagt
    14941 ctctcaaatc cttgccagta atctctaaaa agacatcatt caaggacgct tctttggttg
    15001 ctatttttcc gtaactgatc ttttcttctt gtaagattgt aagaatcggc aacaatactg
    15061 tatttagttc agtagttgtt acttggagct gacctttttt ataagcgatt ccatcagaag
    15121 ctattgttcg ctgaatcgct gacaacacat tttctgggag taatgggatg tcgatcgtca
    15181 aacgatccgc cgtccgtacc atatctttta gagattcttt ggttccttta gcaatcacct
    15241 gtccttgatc catgatcacg atctggtcgc aaagaatttc tacttcttcc atgtaatgtg
    15301 ttgtatagac aatggttgct ccttgtcgat tcagctcctt gatactttct aaaattttat
    15361 tccgactttg ggggtctaca gctactgtcg gctcatctaa aaaaattaac cgcggcttgt
    15421 gggcaatccc acatgcgatg ttcaaccgac gtttcaagcc accactaagt tctcctggac
    15481 gaaacgaaac atatttttct aatcccacta attgaatcac ctcttcaatc aaggctttcc
    15541 ttttctcttt ttcggaaaca tataaaccgc aaaaataatc gatattttct tgcacactta
    15601 gttcgtcaaa gaccgcaacg tcttgaggaa cgaccccaat cattgccttg acagcataat
    15661 tttcaggagt cattgttgtc ccgaacaatt taatggttcc tttgtcataa tttaacaaag
    15721 aaagcataca gttgatggca gtcgatttcc cactgccgtt tggacctaac agacctaaga
    15781 cttctccttc ttgtacttgc agatcaaaat gattcaatgc tacaaaatct ccatagcgtt
    15841 tgactaattt atcaatttcg ataatcatca tgaaaaactc cttccaaatt tcttgttgat
    15901 ctgactataa taaagtgcaa gaaaagaaac tagtgacgat tggctaaacc acacatgaca
    15961 tttgtcacaa tgaaggagtc tgctatgcat aaatctcggc tactcaacga aactagcttt
    16021 ctactggtta tctcattgct tttgctggta agtcaaggat tcgttgctat gcaagttatc
    16081 tatttattga tcgccgtttt attcactggt gtcagttatt tactgcctac aaagccaaat
    16141 tggattttcc aagttattct atttctttta tgtgcctttt tacctgatct tgtcctgttt
    16201 ctgccagcga cgatgcgagt gatcgcccct gaagaaagcc accttgatta cttgtttttg
    16261 ttaggttttt tgttgatttc gacggttggt aatcatcccc ccatcaaggt cgcctttgtc
    16321 gtaattttgc tgtttttttc cttttactta cgaaaaaaag atcaacgaac gaccgatctt
    16381 gagaaaaagt acattgtctc caaagatact cattgggaaa aacaacaaga gttatcggaa
    16441 caaaataaag cattggccct gtcacaagaa acacaattag ccttgcaaat tgtggaagaa
    16501 cggaaccgaa ttgcccgaga catccatgac aatgtcggtc atctgctgtc aagtgcgatt
    16561 ttacaaattg gtgcgcttga aatgatcaat caagaaccaa aactaaaaga accattagaa
    16621 aatttaagtg ccaccgttca cactgggatg gatcggattc gtcaaagtgt ccatgacctc
    16681 catgagacat cgatctcttt tcaacactcc ttagagtttc tgatcgctga ttttccttct
    16741 tctgttacga ttgaaggaaa cttgtttgaa ggattgaatg aaacgcagca aaactgcttc
    16801 ttaatggtca tcaaagaagc cttaaccaac agtatcaaac atagtcatgc caaaaccgtt
    16861 gttttacatt ttcgaacgtt gccggccttt tatcgcttgc aaatcacgaa tgatggcacc
    16921 agcccacaaa aaaattctgc tcccggtatt ggtttgaaaa cgatgcgtca acgtgttcaa
    16981 gaacaaaagg gacaagtcca tattttccaa gaaaaccagc aatttcagtt aacgatcatt
    17041 ttaccaaggg agggacacca atgataacag tagtcattat tgatgatgat ccatttgtga
    17101 cgaaatcgtt acaaaccatt ttagaaagca cgaaagagat ccgtgtgtta ggcattggtc
    17161 attgtgccaa ggatgcgcga aacccatcgt cccgatgttt tgctgacgga catccgcatg
    17221 cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc caaagccatc
    17281 cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt ttccatcggt
    17341 gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt caaatccgct
    17401 tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca aatgatgaag
    17461 aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga gcttgcaatc
    17521 atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt gtacttgagt
    17581 gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt acgggatcgc
    17641 acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa cacaaaaaaa
    17701 cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt caattgtccc
    17761 gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca ggattcgttg
    17821 gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt tctagttttg
    17881 attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat tctttttcca
    17941 tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct aatttatctt
    18001 cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca tatcacactg
    18061 aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat ctttaaaatc
    18121 aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca atcatcggat
    18181 ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa acagcaggtt
    18241 ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt tccactgttt
    18301 ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt agcttttctt
    18361 ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt ccgaccaaag
    18421 aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca ttatccatga
    18481 tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa gtgacatagg
    18541 cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc gtgtagagca
    18601 aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc atcttgaatt
    18661 cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta ttccattcgt
    18721 ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc actttatctt
    18781 cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg aatacattca
    18841 attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg gtgtcgttcc
    18901 aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc attttattta
    18961 acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata tcttgtgcac
    19021 ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca atttgataag
    19081 catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt ggcagacgtc
    19141 cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc cgataaatct
    19201 gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt acttgaccag
    19261 gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata ttcgtcggaa
    19321 tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca tcaacaatca
    19381 aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt ccattcagcc
    19441 ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt cgtttagctg
    19501 ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat tttgaaggat
    19561 ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc acagtagttt
    19621 tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct tcagcgatag
    19681 cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc cgaatattct
    19741 tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg cgctggatcg
    19801 aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta gtctcttctt
    19861 gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga tcaggctgga
    19921 tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat gtctccgccg
    19981 gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag atagctgctc
    20041 gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta tctgcacgtt
    20101 tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg atgatatcca
    20161 aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg aacccgtaac
    20221 gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc tcagcaagca
    20281 tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga tcagcaatga
    20341 ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt ttcttcccga
    20401 ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt gttggctttt
    20461 cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc actaattctc
    20521 cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg actacaatct
    20581 ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact ttgtaaaaat
    20641 tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc atttcttctg
    20701 gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt ttcagttcct
    20761 aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca aggctcttca
    20821 gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa ctcacttagc
    20881 tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc tacgaataaa
    20941 agtgggccat ctttatgtcg ggcaaccgca tctgctacaa cagtttcgat acgtgtgatt
    21001 gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa atgattacgc
    21061 aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg accttctaaa
    21121 gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg acgagcaagc
    21181 tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga ataaattgct
    21241 ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta actttgtggc
    21301 aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca ttgtgtcttc
    21361 ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt ttattttact
    21421 ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa ttctaaatta
    21481 gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt cgataaattc
    21541 aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc gttttcacgc
    21601 ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg ctcttctcca
    21661 tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa atgtagttta
    21721 cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat atttacatca
    21781 ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa acctagtggc
    21841 tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt tccagtgttt
    21901 gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc tctcatattt
    21961 atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt atcaactcgg
    22021 tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt tatcagaaca
    22081 ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc ctcaactttt
    22141 ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag ttccttttaa
    22201 taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg ctttgattcg
    22261 ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat tttcctctgg
    22321 tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt cagcaaactt
    22381 ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat aaaaagcctg
    22441 acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc catcttctga
    22501 gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa ccgcgttgaa
    22561 tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg cttcggcaga
    22621 ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag cattttgaat
    22681 ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa catctaatag
    22741 cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat acatgccaga
    22801 ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt taaccgcatg
    22861 ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat ttttgcatat
    22921 caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga acagctgatg
    22981 attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc cccctcattt
    23041 ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg atacaatgcc
    23101 tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg cgctgaaaac
    23161 tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt gtgtgacaac
    23221 ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt aagttatgct
    23281 ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga cttcgtctat
    23341 aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa attagggacg
    23401 gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga ggccttagaa
    23461 ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt tgacagtatt
    23521 cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt tgaccgtatc
    23581 ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg gcttaaagaa
    23641 ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt cactgcagag
    23701 aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac caaaatcgtg
    23761 gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa tgcttattgc
    23821 aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata ttgaaataaa
    23881 tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct actgctggat
    23941 caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc gccactgtga
    24001 ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt ttccaaaaac
    24061 ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg gtcaagactt
    24121 cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca agtcgacgaa
    24181 cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc agcgaaatga
    24241 agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt aaagaagcgg
    24301 tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac gctgccttta
    24361 ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa tcgctagcag
    24421 cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac aaatgatcat
    24481 cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt gccacatctt
    24541 cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca gaaatcattg
    24601 cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc tgaccttctt
    24661 gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc ttcagcacgt
    24721 acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt gtcatgatcg
    24781 cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca tcgtctgccg
    24841 acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc aagtcaacag
    24901 cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc atttcatcta
    24961 ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc gctaattctt
    25021 taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat tggtagaatt
    25081 gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga atattatttt
    25141 cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt tcatccaaac
    25201 caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt ctgcggctaa
    25261 aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca gatcataaca
    25321 atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat catcaccgag
    25381 cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc ctgtatgcag
    25441 ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact cagtctgtgc
    25501 cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc gggcgatcgg
    25561 caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta aggcctgata
    25621 ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg caaatccatg
    25681 ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt cgcgtcacca catggattac
    25741 ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca ttgtcccatt
    25801 tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta ccagaacgtg
    25861 ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt catgttctcc
    25921 ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca agacattttc
    25981 tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta acagaccctt
    26041 tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt tctcataatc
    26101 ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga tgccaaaaat
    26161 gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa taaattgagc
    26221 ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct tctgtatttt
    26281 ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc aaagtacgaa
    26341 acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata ctaggatgga
    26401 tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta gaaatcgtca
    26461 atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg gctaccatcg
    26521 tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg tccggtgttt
    26581 catccaaata actgatccga acatccagca agggataact aacactttgt tcccggttcg
    26641 ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg taaaacccta
    26701 aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg tagtgatgga
    26761 acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc tcatgatcat
    26821 ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact tctatagtct
    26881 ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct ttcgctttct
    26941 ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg ggagaataac
    27001 cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa ctgataggca
    27061 gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc ttgatattta
    27121 taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg aatctggatt
    27181 tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat caccagatga
    27241 taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg gagaactttc
    27301 atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac aaactgacac
    27361 atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat tggaatatgc
    27421 cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt gacaaattca
    27481 atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag tttcactttc
    27541 aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg ttccatagct
    27601 gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa gttttttcgt
    27661 actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca aaaaggagtc
    27721 gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa gcaagagtac
    27781 gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca gactaatatt
    27841 tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg gatccgtttc
    27901 gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg tctcgaaaca
    27961 acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg tctgcctcgt
    28021 tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc attaatccaa
    28081 accggaaagc ttacaacaaa acgagctgaa ttccctattg aagaaggact tttagctatt
    28141 gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt aggggatgca
    28201 tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc ttatcgtcct
    28261 gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt cattttcaca
    28321 aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg aaagaatcta
    28381 gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat ctatttattt
    28441 gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca atttatcgaa
    28501 gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc tttggtcaat
    28561 ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa tcttgaggaa
    28621 cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc ggcgcagttt
    28681 caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt cggctgtaat
    28741 gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg cggcgatttg
    28801 aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt ttctgatcaa
    28861 aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta caattatgcc
    28921 tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct ttggagaatc
    28981 acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga acatttacat
    29041 acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc taattaa
//
LOCUS       DAFLVO010000034        29096 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.034, whole genome shotgun sequence.
ACCESSION   DAFLVO010000034 DAFLVO010000000
VERSION     DAFLVO010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29096
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.034"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            278..1063
                     /locus_tag="L1U99_001531"
     CDS             278..1063
                     /locus_tag="L1U99_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1212077.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            1076..1927
                     /locus_tag="L1U99_001532"
     CDS             1076..1927
                     /locus_tag="L1U99_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HBN1212078.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(2051..2503)
                     /locus_tag="L1U99_001533"
     CDS             complement(2051..2503)
                     /locus_tag="L1U99_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1212079.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(2968..3336)
                     /locus_tag="L1U99_001534"
     CDS             complement(2968..3336)
                     /locus_tag="L1U99_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HBN1212080.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            3486..3968
                     /locus_tag="L1U99_001535"
     CDS             3486..3968
                     /locus_tag="L1U99_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HBN1212081.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            4005..5015
                     /locus_tag="L1U99_001536"
     CDS             4005..5015
                     /locus_tag="L1U99_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBN1212082.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(5130..5843)
                     /locus_tag="L1U99_001537"
     CDS             complement(5130..5843)
                     /locus_tag="L1U99_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212083.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(6033..6623)
                     /locus_tag="L1U99_001538"
     CDS             complement(6033..6623)
                     /locus_tag="L1U99_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBN1212084.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            7107..7334
                     /locus_tag="L1U99_001539"
     CDS             7107..7334
                     /locus_tag="L1U99_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBN1212085.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            7350..8516
                     /locus_tag="L1U99_001540"
     CDS             7350..8516
                     /locus_tag="L1U99_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBN1212086.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNAHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            8750..9793
                     /gene="hrcA"
                     /locus_tag="L1U99_001541"
     CDS             8750..9793
                     /gene="hrcA"
                     /locus_tag="L1U99_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HBN1212087.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            9887..10450
                     /gene="grpE"
                     /locus_tag="L1U99_001542"
     CDS             9887..10450
                     /gene="grpE"
                     /locus_tag="L1U99_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBN1212088.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            10501..12330
                     /gene="dnaK"
                     /locus_tag="L1U99_001543"
     CDS             10501..12330
                     /gene="dnaK"
                     /locus_tag="L1U99_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBN1212089.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            12481..13647
                     /gene="dnaJ"
                     /locus_tag="L1U99_001544"
     CDS             12481..13647
                     /gene="dnaJ"
                     /locus_tag="L1U99_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBN1212090.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(13729..14394)
                     /locus_tag="L1U99_001545"
     CDS             complement(13729..14394)
                     /locus_tag="L1U99_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1212091.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            14370..14543
                     /locus_tag="L1U99_001546"
     CDS             14370..14543
                     /locus_tag="L1U99_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212092.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(14588..15325)
                     /locus_tag="L1U99_001547"
     CDS             complement(14588..15325)
                     /locus_tag="L1U99_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBN1212093.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(15327..16829)
                     /locus_tag="L1U99_001548"
     CDS             complement(15327..16829)
                     /locus_tag="L1U99_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HBN1212094.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            17088..19082
                     /gene="uvrB"
                     /locus_tag="L1U99_001549"
     CDS             17088..19082
                     /gene="uvrB"
                     /locus_tag="L1U99_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBN1212095.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            19092..21908
                     /gene="uvrA"
                     /locus_tag="L1U99_001550"
     CDS             19092..21908
                     /gene="uvrA"
                     /locus_tag="L1U99_001550"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBN1212096.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            22171..23436
                     /locus_tag="L1U99_001551"
     CDS             22171..23436
                     /locus_tag="L1U99_001551"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HBN1212097.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            23440..24171
                     /locus_tag="L1U99_001552"
     CDS             23440..24171
                     /locus_tag="L1U99_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HBN1212098.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            24306..25190
                     /gene="rapZ"
                     /locus_tag="L1U99_001553"
     CDS             24306..25190
                     /gene="rapZ"
                     /locus_tag="L1U99_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBN1212099.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            25187..26185
                     /locus_tag="L1U99_001554"
     CDS             25187..26185
                     /locus_tag="L1U99_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBN1212100.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            26219..27154
                     /gene="whiA"
                     /locus_tag="L1U99_001555"
     CDS             26219..27154
                     /gene="whiA"
                     /locus_tag="L1U99_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBN1212101.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            27697..28347
                     /locus_tag="L1U99_001556"
     CDS             27697..28347
                     /locus_tag="L1U99_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212102.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            28534..>29096
                     /locus_tag="L1U99_001557"
     CDS             28534..>29096
                     /locus_tag="L1U99_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HBN1212103.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT         9565 a         4897 c         6176 g         8458 t
ORIGIN      
        1 aaggggctgt gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa
       61 gtagcttctt cggaaataag ccgaaatttc ttgaagctga ccacttctgt cacaacctct
      121 ttctttatag aaataaaagg acactagcaa ttcatgaaaa cgattgctag agcgtatcat
      181 ttgctttaga ctatatatct tggtgtacac tcactttaag gcggaaataa aagttatccg
      241 taataacagg tttaggtatg aaaaaggagt gggtactatg tacaaggaat tagaaaacaa
      301 agtcgcagta gtaactggtg gctcaaaggg gattggaaca gcgattgctc aacgattcgg
      361 gaaagaaaaa atgaatgtag ttgtcaacta taactcggat aaagaaggag cagaaaaagc
      421 agtcaaagca atcgaagagg caggcggaaa agcagtctct gtacaagcag atgtcagttc
      481 tgaagaagga atacagcgtt tacttgatac ggctttagaa aattttggga cactggacgt
      541 ttgggttaat aatgctggga tggaaaatca gcatccaacc catgaactta gccttgaaga
      601 ttgggaaaga gtgttaaaag tcaatttgac tggcgttttt atcggaacga aagcggcttt
      661 aaattacttt acagagaata ataaaaaagg aaatatcatc aatatgtctt ctgttcatga
      721 acagatccca tggccaacgt ttgctcatta cgctgcttca aaaggcgggg taaaattatt
      781 taccgaaacg gtagcaatgg agtatgcacc gaagggaatc agaatcaata gtataggccc
      841 tggtgctatc cgtacaccta ttaatgcggc aaaatttgat gatcctgaac aaaaagaact
      901 cttggaaagt atgatcccac taggacgcgt aggtgaacca aaagaaatag cggcgacagc
      961 tgcatggttg gcttcagacg aatccagtta tgttacaggt attacactat ttgcagatgg
     1021 tgggatgact ttatatcctt ctttccaagg tggaaaagga taagggtgaa taaaaatggg
     1081 tttattgatt gcattgatcc cggcagttgg ctgggggatc cagccactga ttttgaaaaa
     1141 gattggtggc agaccaacaa atgagatatt aggaactggt attggagcgg tgcttgtcgg
     1201 cttactcgtt caattattcg cttctccagc tggtatttca gtgactacat ttttgattag
     1261 tttactttct ggtgcatttt gggttattgg acaaacagga cagtatacat ctttcaactt
     1321 gattggtgtt tctaaaacga tgccaatttc gactgcatta cagttagtcg gaacctcgtt
     1381 gattggtgtc ttcgcttttg gagaatggtc tggaagtatg gggaaaatca ttggagcagc
     1441 agcaatcatt cttcttgtat ttggttctgc tttaacggca atcagtgatg atcctggaaa
     1501 aaaaggcggt atcacaaaag gaattagtct attagcatca acaagtattg gttattgggt
     1561 atacagtgca ttgcctaaac tagttgatgc aagcggactt tccattttct ttccgcaaat
     1621 gatcggtgtc tttttagggg cagtgattta tgtgattttc cgtaaaccaa ccgcattttc
     1681 tgaagacaag agttggaaag caacgatcgt tggagccatc tttagtgtgt cagcattggc
     1741 ttatattttt tcagcaaatg aaaatggggt tgctactgca tatatcatta cacagctaaa
     1801 cgtagttatc tctacattag gcggtatgta catcctgcat gaaaataaga caccaaaaga
     1861 aaaaaaatta acgattatcg gattattgct gatcgtagta ggaagcatgg tcacggtctt
     1921 tatttgagga taaagatggt aaaatttcat ttattaaaaa aatatttgtt tgaaccaaac
     1981 agtaagtact tataaaaaaa tagcgctaga atttccaaca tctctggaat ttctagcgct
     2041 ttttaattgt ttaagataca agggaaatat ctgtctggat caataatttt tcattgatcc
     2101 attgactaaa gtttacgaca taattgaagt taccaccgat tagtatctcc gcatgattgt
     2161 ctttataaag atcgtattgt aaaagacggt cttttttatt tgcgtaaaca tcgttatggt
     2221 actggactaa ttgttctcgg aattgattga ttgctgtaaa atcacgatat tgaaggttga
     2281 aacgcatcgt gattggtgca tttagcatga atcgctgcat ttcttttgct gcttcctctg
     2341 cttgatctcc gtataggaac tcaaaaagat tacgttcaga aaatttccat tgcccgccaa
     2401 cctttgttcc ttttagtttt ccttcatgaa gataatttct gatagaacgt gtagtaacac
     2461 ctaattgttc ggctaattca tttactgagt aaaaatcttt caatgttcac cctcctatgt
     2521 gaatggttct actgacttag ttgatatttg cttaatcacg aaatgtagaa agaacgattt
     2581 taattaaggt cattgtaaaa atcaagtcag aaaattctaa cttttatttc tctaaagaaa
     2641 ttcgttctct cctaaagtga tattatattt aaatatacct gaaaataatg ggcagtatta
     2701 tgaaagatca ctgatatttt ctcgtatttt ttccttattc aaaagttttg caggaaaatt
     2761 gctgaaaaaa taattttact aagtagaaaa ttcaaagcca ttcaatcagt gatttttttc
     2821 agcacaagaa agactcctta taaaaatagc agatactttg tcaattaagt gtttaaccag
     2881 ggatgataaa aaggatagga ttgaacaaaa cctgtataag gtgatgaata gtttcctcgc
     2941 cagtaaaagg tttattcgta taaagcttta tcgccaaaat ttatcatgac cttttttatc
     3001 ttcaatatta aatgaaatca attgttcaat caattcccag ttgattacac ttttccaagg
     3061 aactttgatg acgttatccg tatatacgta gcctgcttct tggatatttt tttcaagggc
     3121 acgaatcgct gctttttccg gtgcgataga aaaatgattt ttagcaaaac taaatgcaat
     3181 aataaaggta ccatggtcag taaacatagg ttggttccat tttacagttg tgtctagctg
     3241 gggatacgtt tctgttatct tagcaaaaag gtctttgatc ttttgttgat gttctttttc
     3301 tttgatttga ttgatgatcg gctgaaattt ttccattcta aaacgcctcc attaagtggt
     3361 ttgatttatt ttaccagaaa aacaatagtt atgtataaaa aacgaacaaa acacaagtaa
     3421 tgttgtaacc gctatattta tatgataaga tgtctcaaat aataaaatag aaaagagaca
     3481 taaaaatgat tgacttggca aagaaattct tacacgaaaa tatatatttt gagttgtatc
     3541 atcatcgagc catttataca aatgaagatg ctttggtaat aaagaaagaa caaggattta
     3601 caggtacaga gaccaaaagc ttattcttaa aagataaaaa agataataac tacgtatatc
     3661 tgacttttac tacgaaacaa acggatttca aagcattagg gaagatcgtc ggtaaaaggc
     3721 tttctattgt ttcatcagaa cgcatggaag aacaaacggg acaaaagcag ggcgctgttt
     3781 ctccgtttgg ttatgaaaaa cagattccga ttattattga tgaagagctc ttatcaaatg
     3841 aaaaacttgt ttttgcacca ggtagaccag atcaaacgat ggtcatccaa acggttgact
     3901 taaacaaaat catccagcta cttgagatgc cgatattttt gatgccggca aacgaaaaaa
     3961 acaattaacc aagtaaaata gtgcatactt ggaggtgaag caacatgata agttatccat
     4021 tattagaaag aaatgcaacg attggggtta ctgcaccatc ctcaggcgta tcagaggaac
     4081 accattcgtt actcgaatca gctttaaaga gaatggaaga aaaatctttc caagtagtta
     4141 ctggaaagac gctttggacg caagataagg aaaaatcagg tccagcaaga aaacgagcag
     4201 atgaattcaa tcaaatgatg caagatgaaa atatccaaat gatctttccg acttggggag
     4261 gagaattatt gattgagatt ctcgattttg tcgattttga tgctctacaa ccaaaatgga
     4321 tagtaggtta ttcagatatt agtacgttgc tacttgctgt cacattaaaa acagggatag
     4381 ccactgcaca tggaactaac cttattgatt taagaggaga gtacttggat gaaacgacag
     4441 caatgtggga aagtgtactg aaaacaagag aaggagaatc gattctacag caatcttctg
     4501 aaaagtatca aaaagtgtgg ccccatgagc attcatcatc ttctgttttc catctcactg
     4561 aaccaacaaa ttggcaatca gtcagcggag atgcagtaag gatgaaggga cgattattag
     4621 gtggttgtat tgatacgatc aggcatttaa tcggtactcc ttatggagat gtccaatctt
     4681 ttaaaagaaa gtataatgat ggaaagccga tcttgtggtt tctagaaaac tgtgagctat
     4741 cgtcagttga tttaagaaga tcacttgttc agatgaaact ggcaggctgg tttgatggca
     4801 gctcggggat catgttcggt agaagtgcgg cagaggattt gttagattat aaaatgaagg
     4861 atgtatacga agatctgtca aaggaattaa aactaccgat cttgtatgat attgattgtg
     4921 gtcatgtacc gccacaactg acattgatta atggtgccta tgcagaagta gcggtagaag
     4981 atagaaaagc gactgttttg caaacgttta tttaaaaaat tttttcctgc cttggagtct
     5041 atcaaagacc aataaatcta aatagaaaag aaagtgaaag aagctgacaa aatgctgtca
     5101 gcttcttttt gtataacata ttagaaagtc taattatcta taactgtcac atcgattaac
     5161 tgtttcacgt cattgggatt tcctgtagga atagctacta cagatgcatt atcaatgatt
     5221 tcttgagttg tttctctaat gaacgctgga taagatgttt gatctgcagg catttgccaa
     5281 tgtgaaggaa ctggataact agtgattgtc ccgtcatggt tacttgaata cactaaaact
     5341 ccctggtaac tgtatttccc agtgagcata accacatctt tcggatagac tgcactccct
     5401 gcatcataag gggcgatagg tgttcctgca ggataatgaa taacatgtaa ttcgaaatca
     5461 cccgatgtat ctctaaaagt attacctcta atagctagcc aaacacgtgc gtactcaatt
     5521 tgtagatcag aatatcctgc taacggatct attgactgag aagactgtga ggaggttgtg
     5581 tctattgttg aagaagaaat atttgtctca actgtactac tagatgtaga agaagtattg
     5641 ggctctgaga ctttactgct tgttgaagat gtattcgttt cagtagaagc tgatttctga
     5701 gtacttgatt tttcagctga actggtttgt ctgattgaac ttttgtctgt ggtcgcagat
     5761 ggatcactat tttctttact aggagacgta catcctacaa ggaataaaga gaccaacaat
     5821 aaaataaaac ctaacttttt catataaaat acctcattat ttttttaata ccagtatagc
     5881 ataatcctga atttttgaat ccgtaaaacc ttgtctatga atataaatag agtgtatctt
     5941 ctttgataaa tgtcagaaaa agtgtgacaa ataatcatca gtaaaattac ttgtcacact
     6001 attgataagg agtatttaat tgaagagaat gattaggaga aaggatctcc gtacttttta
     6061 tagtaatcat agaatccaag tttgtataga cgaatcgttt tttctcttat ttcttctgtt
     6121 tcaaaatgga ctgcttgaag aatcaagtct gtgaattcta taggagctgt tccattcgca
     6181 gtaatcaaat tacgatcttt cacagcttgt tgttctataa aatcttcttt attctgataa
     6241 ttttccgatt ctaaccaagg aaattgcgca tttccggtgt gtttgtaacc ttgcaataat
     6301 ccgctctgag ctaaataatc aactgcccca caaatagcag ctactggtac gtctgttttt
     6361 aacaatttat cgattatttg atataaatga tgatttttta tgtcccatga attgccaccg
     6421 atcataataa aaaggtcaac tttttcaggt atttgttcga ttaagtaatc gatttttgtt
     6481 tttaatcctc caatggaagt gacctctgat tggatagaag cagttttgtt ttgccatttc
     6541 tcattttggt ttagtgtgct agtaatataa gcaccttccc aatcggcata ttcctctaat
     6601 agaaacgtaa tcgcagtttt cattttcaag ctctccttta ctatctataa caaggacaac
     6661 agttttaacc tacagacatt cattaaaatt gggtagcgac agcgaaaaca acaattctta
     6721 agttttagac agagtataca gatagtcaac ttaattaaat acgaactaaa taaaaatgac
     6781 aggtaatcat ttttgtttac cagcattata acattttgca tacatggatg acaaaagaac
     6841 caattcccac ttgcttgagt acaatattaa aagaaactgg aaggcaaaaa gtaattatag
     6901 aaacgaaaaa taaatcatat cgggcactca gacatgaaaa caaccctaga gatatataac
     6961 taggtaacca gtttaatgaa agaaaaaatc atccaagaag tcgattcttg gattttttag
     7021 tggatttgtt cgccaaatac gtttagtatg cgtatatgag aggttgtaag caaagcgttg
     7081 tggtctgagc acttaaggag gaatctgtga aaatagcttt tcatattttt gcagattttg
     7141 acttaatgcc gaaggtcagc tttgcgatta ccgtttatcg agaggctgta aaagcaccgt
     7201 gtagctccga tgacaataag caagcatttt tagagctagg tttccttgat tctaaatatg
     7261 cggcttattt caatgagttg gtgcttgaac gcgattttaa gaaggtcgaa aacaggcacg
     7321 acttttcgac gtaaggagaa agaatttcaa tgatagaaac aataaatccc gcagaaaaca
     7381 aggtttctgc gtacattcat atcccatttt gcgagcatat ctgctattac tgtgatttta
     7441 ataaagtttt tttagaaggg cagccagtag atgagtatgt ggaaatgctg ctgaatgaaa
     7501 tgaaaataat gctagaaagt catccgacag cgaatttaga aacactttac gtagggggcg
     7561 ggacaccaac ttctttatct gctaaacaac ttgatcgact gttatcaggt gctagagaga
     7621 tcctgccttt tcaaaatggt aatgagttta ctgtagaagc gaatccaggt gatttgaccc
     7681 gtgaaaaact tcaagtaatg aaaaactatg gcgtcaatcg tttatccatg ggagtgcaga
     7741 catttgataa tcgcttattg aaaaaaattg gacgtaaaca caccgcagaa gatgtgtatc
     7801 aaactatgca atttttagaa gcagaaaatt ttaccaatgt aagcatcgat ttgatttatg
     7861 cattaccggg acaaacacta gaaggatatc tggatacttt ggaaaaagct ttggctttgg
     7921 atctgcctca ctattctttg tactcattga tcctcgaaaa caaaacaatg ttcatgaact
     7981 gggtacgaca aggaagactc gaactgcctg atcaggaaac ggaaaccaga atgtttgaag
     8041 agacgattga agcaatggaa aagcatggac gtcaccaata tgaaataagt aactttgggc
     8101 tctccggaca tgaatctcaa cataacctca tgtactggaa caatgcccac tattttgggt
     8161 ttggagctgg tgctagcggt tatcttggag atattcgtta ccgcaacaaa ggaccaatcc
     8221 aacactattt acgcccatta cgagcaaatg aacgcccggt attggaagaa gaaaaattga
     8281 cacgaaaaaa tcaaatagaa gaagaaatgt tcttaggact aagaaaaaaa acagggatta
     8341 ctaaaaaaca tttctatgat cgctatcaaa aaacaattga atcggtgtac ggtgatgtgc
     8401 taagggaatt agagcaagaa gggttacttg ttaatgaaga agaccgtgtt tatttgacac
     8461 caagagggac ctttttgggg aacaatgtgt ttgagcgctt tttgtttgaa aaatagttta
     8521 aagaatattt gttttttatc tgaatttaaa taaaaaaagt tcaaaaatac aataaaggac
     8581 tattgaaacg ttgatataac tggatttaca tcaattattt agaattagca ctcttgtgtt
     8641 tagagtgcta aaaaatggag tctttctctt gacaggagaa gggcttcttg ctatatttat
     8701 aagtggatta gcacttagaa tatatgagtg ctaatgagag gtgaggaaga tgttaacaaa
     8761 gcgacaaaac gacattttac gtctgatcat ccaacactat acgagtagtg gcgtgcccgt
     8821 tggttccaaa acattgatgt ctgagggagt caaggccagc tcagcaacga ttcgcaatga
     8881 tatgaaagca ttagaagatg aaggattgct gttgaagact cactcttctt ctgggcggat
     8941 tccatctgct ttaggctatc gttattacgt ggatcatttg ttaaaacctg ctcgcgtagc
     9001 agaagatgat ttgctgctga ttcgtcagtc tctaggcaga gaatttcatg aaatcaatga
     9061 gattattaag caatctgctg agatattatc tgagctgaca agctatacga ctttttcatt
     9121 gggacctgaa ataaaagacc gccgactgac tggctttcgt atcgtaccct tgaataatcg
     9181 acagattatt gctatcgtcg taacagatat ggggaatgta gaaagccaag tgttcactct
     9241 tcccgaatat atgggaagtc aggaactaga aaaaatggta cagattgtaa acgaccgtct
     9301 agtcggagat cctctgatga cggtgtacca taaacttcgt acggagattc cgatgattct
     9361 tcataaatat ttccaaacga cagaagggat gtctcagtta tttgacaccg ttcttggtca
     9421 tgtttttgaa gataaggttt atgtcagtgg acaaatgaat ctcttggatt atgagccccg
     9481 tcaagatctt gatcagttca aatcgatgtt ttcttttatg aaagactcag acggacttac
     9541 acaaatgatc actccgatgg atagcaatat tcatatcaag attggtgctg aattaggcaa
     9601 tgatttattg cagaatatga gtatgattca agcaagttac gagatagatg gtcatggaag
     9661 aggtacaata gccttgttag ggcctactag tatgccttat tctcggatgt tcggtctagt
     9721 cgatgtttat cgaagagaac tagcagctaa acttgctgat tactaccgtt cgcttgactt
     9781 gtcaaactcg taatgtgaat aacgaagcta tttgcagctg atcgttctct ctttcttagt
     9841 aagagcaatc aaacagctga ctgaataatg aaaggaagac tgtatcgtga aagaaaatca
     9901 agaagaacta gataaagaaa tgacagatgc tcagccagaa ccggaaatcg atgtcgaagc
     9961 tgcagaagat tcgggtattt cagaagctga agcggaagaa ttcgaaacag cgaaattaaa
    10021 agctgagtta gaagaaatgg aagataaata cttgcgggct cgtgctgaaa tcgcaaatat
    10081 ggcaaatcga ggaaaaaatg agcgtgagca attacaaaaa taccgttcac aagatttagc
    10141 caaaaaatta cttccatcaa ttgacaacct ggaacgtgca ttagccacag aagtgtcaga
    10201 tgatcaaggg gcaggtttga aaaaaggcgt ggaaatggtc ttggaaagtt tgcgtaacgc
    10261 actggaagaa gaaggaattg aaaaaatccc tgctaaagga gaagcctttg atcctaatct
    10321 tcatcaagca gtacaaactg ttccagcgac tgaagataca ccagccgata cgattgtaga
    10381 agtactacaa gaaggctaca aattacatga tcgcgtgtta agaccaacca tggtcattgt
    10441 tgcacaataa ttgtgcggat ataaaactta cactttcaat taaagaagga gacgttaatt
    10501 atgagtaaaa ttatcggtat tgacttaggt acgactaact ctgcagtagc agtattggaa
    10561 ggaaacgaag caaaaatcat cgctaaccca gaaggaaacc gtacaacacc ttctgttgta
    10621 tcattcaaaa atggagaaat ccaagtaggg gaagttgcaa aacgtcaagc tgtgacaaac
    10681 ccaaatacga tttcatcaat caaacgccat atcggtgaag caggttacaa agtagatgta
    10741 gaaggtaaat catatacacc acaagaaatc tcagcaatga tccttcaata tatcaaagga
    10801 ttcgcagaag actatttagg tgaaaaagtc gaaaaagcag ttatcactgt gccagcttac
    10861 tttaatgatg cacaacgtca agcaacaaaa gatgctggta agatcgctgg tctagaagta
    10921 gaacgtatcg tcaatgaacc aactgcagct gctcttgcct atggtttaga taaaacagat
    10981 cgcgacgaaa aaatcttagt attcgacctt ggtggcggta cttttgacgt atctatcctt
    11041 gaactaggag acggtgtctt tgatgtattg tcaacagctg gcgacaacca tctaggtggg
    11101 gacgactttg ataacaaaat catcgactac atggtagcag aattcaaaaa agaaaacagc
    11161 attgacttgt ctcaagacaa aatggcttta caacgcttga aagacgctgc tgaaaaagcg
    11221 aaaaaagatt tatctggcgt atcaagcaca caaatcagct tgccatttat cacagcagga
    11281 gaatctggac cattgcattt ggaaatgaca ttgacacgtg caaaatttga tgaattaaca
    11341 gctgacttag tagaacgtac aaaagtacca gtacgtcaag cgctaaaaga tgcaggttta
    11401 tcacaatcag aaatcgacga agttatttta gtcggtggat ctactcgtat ccctgcagtt
    11461 gtagaagcag tacgtaaaga aacaggaaaa gaaccaaaca aatcagttaa ccctgatgaa
    11521 gtagttgcta tgggtgctgc tatccaaggt ggcgtgatca ctggtgatgt gaaagatgtt
    11581 gttttacttg acgttacacc attgtcatta ggtatcgaaa caatgggtgg agtgttcact
    11641 aaattgattg accgcaatac aacgattcca acaagtaaat cacaagtatt ctcaactgcg
    11701 gcagataatc aaccagcagt agacatccat gtattacaag gtgaacgccc aatggctgct
    11761 gacaacaaaa ctctaggaag attccaattg acagatattc cagcagctcc tcgtggtatt
    11821 ccacaaatcg aagtaacatt cgatattgat aaaaacggga ttgtaaatgt atctgcgaaa
    11881 gatctaggta cacaaaaaga acaaaaaatc acgatcaaat cttcttcagg tctaacagac
    11941 gaagaaatcg aacgtatggt aaaagatgca gaagcaaatg cagaagcaga taaagctcgt
    12001 aaagaggaag ttgacctacg taatgatgta gatgcattgc tattctctgt ggacaaaaca
    12061 ttgaaagaat tagaaggcaa agtggacgaa gaagaagtga aaaaagcaga aacagctcgc
    12121 gatgaattga aagccgctgt tgaagcaaac aacatcgaag aaatgaaaac taaacgcgat
    12181 gcattgaacg aaatcgttca aaacttgact gttaaactat acgaacaagc ggcacaacaa
    12241 caagctcaag aaaacccaga agcagctcaa ggcggagcag atgatgtcgt tgatgctgat
    12301 tttgaagaag tcgatggcga cgataaataa tcagttcact gaatttcgag agaaggccaa
    12361 agttgctact ttggcttttt cttttgaaaa atagtttgaa gtatcggttt ttgtttcaaa
    12421 caaaatatga tatgataaca agcgacgtga aaatgatgag aaccaatagg aggaaagcct
    12481 atggcaacaa aacgtgatta ttatgaagtc ttagggctct caaaaggagc atcagaagat
    12541 gaaataaaga aagcttatcg taagctttcg aaaaaatacc atcctgacat caataaagaa
    12601 cctgatgcgg aagaaaaatt caaagaagta tcagaagcat atgagatttt aagtgacccg
    12661 caaaaacgcg ctgcatatga ccaatacggg catgcaggca cagatccaaa ttacggtgct
    12721 ggtggagctg gtggcggatt tggtggattc ggcggcttct ctggtggcgg cttcggtggt
    12781 tttgaagata tcttcgactc tttctttgga ggaggcggtc ggtcagtcga tccaaatgcg
    12841 cctcgtcaag gtgctgattt gcaatatacg gtcgacttgt cttttgaaga agcgattttt
    12901 ggtgtagaaa aagaaatcaa gtataatcgg gaagaaatct gtcatacttg tggtgggaac
    12961 ggtgcaaaac caggcacaca accaactact tgtcataaat gtcatggtgc aggtacgatt
    13021 aatgtagaac gccaaacacc acttggacga gtgatgagcc gtcaaacttg tgatgtttgt
    13081 catgggacag ggaaagaaat caaagaacct tgtccaacct gtcatggctc aggacatgag
    13141 aagaaagcac attcagttaa agtgaatgta ccagctggtg tagaagaagg acaacaaatg
    13201 cgtttagctg gtcaaggaga agctggagaa aacggcggac catttggtga tttgtatgtg
    13261 gtcttccgtg tagaagaaag tgatatcttt gatcgtgaag gttctgaaat ttactatgaa
    13321 ttgcctttaa gttttgtaca agcagctttg ggggatgaag tccaagtacc aactgtccat
    13381 ggagatgtga aattgaagat ccctgctgga acacagacag gtacgaactt ccgtttacgt
    13441 ggaaaaggcg ctccgaagtt acgtggtggt gcaacaggcg accaacatgt caaagtaaaa
    13501 ctgatcacac cgaaaaatct aaatgaacaa caaagagaag cattacgtgc attcgctgaa
    13561 gctggcggca tcaaagttga agaacagcaa gaagacggtt tcttcgataa gtttaaagat
    13621 gcttttggcg ggaaaaagcg gaagtagttt ttctagtaaa aacgctaagt cattaataat
    13681 taaaaaccag acgaacaatc atatgttcgc ctggtttttt tgtagttgtc atgtttgtac
    13741 caacaaaaaa gccagcttta gaatatgata atcgtcatag tttctagggg tataaccagt
    13801 gagagaatgg aacttgttca atcgatattg caaggtgttt ttatgaataa ataattcttc
    13861 tgagcaattt ttgatgcttc cgttattttt actgaagcat gccaaagtct tcttgaacaa
    13921 atgtacttct tcttctgtca ggcttttcaa aatacgtttt acatataatg ttcgttgatc
    13981 tgacgggatt gctggtaaaa cgatcccgag gtctaaatct tcaaaaaagc ggatctcgtt
    14041 cacagattga tggaaagcta tccattcgca aacttgtttg gcatgaagga aagattgcgg
    14101 tgtctcttgc tctgtataac aaagcgaccc aattccaaag tttagctgta actgatacat
    14161 tttattaaac tttgtctgga ttttatcaag caatgatagc aatgaggctc tggaaatccg
    14221 attgactagg ataatgattt gttgtctatg tacagtgagc aaagcctgtc cgtaataaga
    14281 gaagaccctt tcgagcaact ccaataaagg attgatccgt tcttgacaca attgctgatt
    14341 gtcagaaagt tgtcccacaa ctacataata tggagaagaa aaatcaagct caattaagtg
    14401 agggtggtat cgactatgta cttgatatca tcaatgaacc gatggtactt tcttatgcga
    14461 tggaacaggt agagcgattg cttgtttgtg caggaaaaca agcgatgcgg ctgatacgat
    14521 taggtgagaa aataagaaga taaaaataca cggtcccttc atggcgaccg tgcatttttg
    14581 gtttttatta aatatttaat actttattca agaaatcttt tgtccgttca ttttgcggat
    14641 tttcaaagat ttgttgaggc gttccatctt ctaaaaagtt tccgtcgtca atgaacatga
    14701 cgcgattggc cacttcttta gcgaacccca tttcgtgcgt aacgataacc atcgtcatac
    14761 cttgttctgc taactttttc atgacgttca agacatcacc gaccatttca ggatcgagtg
    14821 cagaagtagg ctcatcaaaa agcatgatgt cagggttcat cgctagagca cgagcaatag
    14881 ccacacgctg tttttgtcca ccagaaagca tttcaggata catatctttt ttatcttcta
    14941 gaccaactgt ctgcagtaat ttgattgctt ttttctctgc ttcttctcta gattctttct
    15001 tcaggtccat cggtgctaaa atgatgtttt ccaaaataga aagatgaggg aataggttaa
    15061 agtgttggaa taccattccg atatgttgtc tcaccaagtt gatatctgtg cttttatcca
    15121 tcaagtgggc gccgtcaata ataatttcac cgtcagaagg ttcttctaaa cgattcaagc
    15181 aacgcaagaa tgtacttttt cctgaacctg aagggccaat gatacagacg acatctcctt
    15241 cgttgatgga tacattgatg tcgtttaata ctgtgttatc gccgtatttt ttgactaaat
    15301 gctcaactaa gattttttct gccatcttac ttcaccttct tttctaaaac ttttgctaat
    15361 tttgtcaatg ctgtgatcaa aatcaagtac atgatcgcaa tgatcaagta aacatacgta
    15421 ctttgtgttg tacgtgcaac aatgatctta ccagtttgca gcaattcgac tacaccgatt
    15481 gcggaaatga tcgttgtgtc ttttaatgag ataacgaact gattgacgaa tgatgggatc
    15541 atgatgcgta tcgcttgcgg caaaatgatt ttttgcattg tccgattata agaaagacct
    15601 aaacttctgg aagcttccat ttgtccgaca ggaacggcgt tgatcccgcc tcgaacaatc
    15661 tctgcgatat aagcacttgc gttaagagtc aaggtgataa caccagcaag gaagtcagga
    15721 atcgtaaatc caacgatacc aggcaaccca aagaaaataa agaacgcaag aaccatcatt
    15781 ggaattcctc ggatgatatc gacataaata ctagcaattg tgcgaagagc gcgtattggt
    15841 gctacactga ataatccaaa aatcacaccg attactatag ccaaagcaaa ggagatcaaa
    15901 gttaggagaa ttgttctcca aagtcctttc aacaatgctt gatagttgtt ttggataagt
    15961 ccaagaaatg ttgattcatc agcagtggaa gactcactgg aagtttctga accatccgct
    16021 acatattctt taataatctt atcgtattcg cctgttcttt ttaattcttt caatccttca
    16081 ttgaacatat taagaagctc aggattttgt ccttttttaa cggcaaatgc atattttccg
    16141 ccagattctt ttttgatcgg tgtttccaat tcttgtcctt gtttgatcgc ataaccgatt
    16201 accggataat catccatcat tgcatcgatt gcgccaactt ttaacccgtc gtacaattga
    16261 tcagcagcat caaaatattt gatagaatag ccatattcag attcatggtc gcttaaaaat
    16321 tcagcacttt cggtaccaac ttttgctccg actgtttttc ctttcaaatc ttcataagac
    16381 ttgatcgaag tatctccttt tttgacagct aattggatcc cgctatcaaa gtaagaatca
    16441 gaaaaatcat agcttttctt tcgttcatct gttacagtca ttccggcaat cattccgtct
    16501 gcttgtcctg attccaaagc ttgcaaagca gcagagaaac cacggtagtc cattcggatg
    16561 ttaaatcctt gcagtttggc gatgttttcc atcaatttta catcgatgcc ttcgtactcg
    16621 ccctttgcgt tttgaaattc aaatggagca aaagcagagt cactggcaat tacgtatacg
    16681 tcttttttgg gctctatttt ttgcattgtc tcgcttgtgc ttgactctgc cgttgtagtg
    16741 ttgtcagctt gtgcaacatg accaaacgca agtgtcacaa gtcctgtcat taagaaaaca
    16801 aatgagtgaa ataaatgctt tcttttcata atcaacctcc taaatttcca atattttatt
    16861 attataggcg aaaagtgctg aatcagacaa gactgtaagc tcgaaaaaat gaaaaaaatg
    16921 cgagtttcta acattttatg ttataaaaca taacatgtat aataagataa aaaagtggcg
    16981 aaagtatgtt cggtgtggta taatttttta gtaaggaatg cctttgcttt ccttttcttt
    17041 ttattggtcg taaaatgaaa aggaatgaat gaaaaggagg acgaagaatg attgagagag
    17101 atacctcccg acactttgag cttgtctcga aataccaacc ggctggtgat cagcctgaag
    17161 cgattaacca attagtggat ggcgtagtcg gcgggaaaaa agcacaaatc ttattaggtg
    17221 cgactggaac agggaaaaca tatacgattt ccaatcttat tgagaaagtg aataaaccaa
    17281 cactgattat tgcccataac aaaacattgg ctggtcagct gtacggggaa ttcaaggaat
    17341 ttttccctaa caatgctgtt gaatattttg tttcttatta tgattattat cagcctgaag
    17401 cttatgtgcc ttcaagcgat acgtatatcg aaaaagattc aagtgtaaat gatgagatcg
    17461 acaaattacg acattcggct actagttcat tattagaaag aaatgatgtg atcgtcattg
    17521 catccgtttc atgtattttt ggattaggct cgccttttga gtaccaaaaa caagtagttt
    17581 cgattcgaca gggagcagaa ctagatcgca atcagttgat tcgtgactta gtcagtatcc
    17641 aattcgaaag aaatgatata gattttcagc gcggtcgttt tcgagtgcgc ggtgatgtcg
    17701 tggagatttt tccggcttca agagatgaac gtgccttacg tgtggagttt tttggagatg
    17761 aggtcgaacg tatccgagaa gtcaatgcac tgacaggtga agttttagga gaaacggaac
    17821 acgtagcaat cttcccggcg actcactttg tgacgaatga tgaacatatg gagcatgccg
    17881 tagcgaatat caaagcggaa ttagaacagc gtttaactgt cttgcgaaat gaaaacaaac
    17941 ttctggaagc tcaacgttta gaacagcgaa ccaattacga tattgaaatg atgttagaaa
    18001 tgggctacac gtcgggaatt gaaaattatt ctcggcatat ggacggacgt aaagaaggtg
    18061 aaccgcctta tacgctattg gatttctttc ctgaagattt tttgatcgtg gcggacgaat
    18121 cgcacgtaac catgcctcaa atcagaggaa tgtataatgg tgaccgagcg agaaaacaga
    18181 tgctagtaga ttacggtttc cgtttgccat ctgctttaga caatcggcca cttcggttag
    18241 aagagtttga aaaacatgtc aatcagatca tttatgtctc tgcgacgcca ggaccatatg
    18301 aacatgaaca aacagatacc gttatccaac aaatcatccg tccgacaggg ctgcttgacc
    18361 cagtgatcga agttcgtcca atcatgggac aaatcgatga tctagtaggc gaaataaatg
    18421 aacgagtcga aaaagaccag cgggtgtttg taacgacatt gacgaaaaaa atggcagaag
    18481 acctcacaga ttatttcaaa gaattaggga tcaaagtcaa atatttgcat agtgatatca
    18541 aaacgctgga acgaacagaa atcattcgag atcttcgatt aggtgaattt gatgtgttag
    18601 ttggaatcaa tttgcttcgt gaaggattag acgtacctga agtttccctt gttgctatct
    18661 tggatgcgga taaagaaggc tttttacgta gtgaacgttc cttagtccaa acgattggac
    18721 gagctgctcg gaatgaagaa ggtaaagtaa tcatgtacgc agacaaagta acagattcta
    18781 tgcgtctagc gatggatgaa acgtcaagac gtcgtacgat tcagcagaag tacaatgaag
    18841 aacatgggat cgttccaaaa acgatcatta aagaaatccg agatttgatt tctattacga
    18901 aagaatcgga agatgataca aaagaagcgg tacaagtctc gtacgaagaa atgacgaagg
    18961 aagaaaaaga cacgttattg atgaaattag aaaaagaaat gaaagatgcg gcaaaagctt
    19021 tggattttga aacagccgcg aatgtgcgag atatgatttt agaattaaaa gcttcaaagt
    19081 aggaggacaa catggctaac gataaaatta cgattcatgg tgcacgtgcc cataacttga
    19141 aaaatataga tgtaacgatt ccacgagata aattcgtggt cgttacaggt ttgtccggtt
    19201 ctggaaaaag ttccctagca tttgatacgc tgtacgctga agggcagcgg agatacgtag
    19261 agagcctttc tgcttatgct cgtcagtttt taggacaaat ggataagccg gacgtagata
    19321 gcatcgacgg attgagtccg gcgatttcta ttgatcagaa aacaacaagt aaaaatcctc
    19381 ggtcgacagt aggtactgtg acggaaatca atgactattt acgcttgttg tttgcacgtg
    19441 taggacatcc gatttgtccc aacgatcata tcgagattac cagtcaatca gtagatcaaa
    19501 tggcagatca agtaatggct ttgcctgagc gcacaaagat ccaagtgttg gcaccgatcg
    19561 tggtaaagaa aaaaggacaa cataaaaaaa tattcgaacg aatccaaaaa gagggatacg
    19621 tccgcgttcg agtcgatggt gagatctatg atttaagtga agtgcctgag ctggagaaaa
    19681 acaaaaaaca tgatatcgcg atcgtcatcg accggatcat tgtgaaagaa gggattcgtt
    19741 ctcgcctatt tgattcttta gaggcggccc tgcgattagc agacggctat gctctggttg
    19801 acgtgatcgg tgaagaagaa atgttgttta gcgaacacta tgcctgtcct tattgcggat
    19861 ttactgttgg cgaactagaa ccaagactgt tctcattcaa tgcgcctttt ggagcttgtc
    19921 cagactgtga tggtttaggt gtcaaattag aagtcgatca agatttagtg attccagata
    19981 gaacgaagac acttagtcaa ggtgctatcg ttccatggaa tccaatcagc tctcagtatt
    20041 atcctcaaat gttagcgcag gcttgtgaaa gtttcggtat cgatttagat acaccattcg
    20101 aagaattacc ggaagagcat caggagatca tcttgaatgg gacagatgat cttttccatt
    20161 tccattatga aaatgatttt ggtggcgttc gcgatgtaga aacgactttc gaaggggtat
    20221 tgaagaatat cgagcgtcgt tatcatgata cgaacagtga tttcacgcgt gagcaaatgc
    20281 gtctttatat gacagaatta acttgtcaga catgtaaagg ttatcgattg aatccccaag
    20341 ctctatctgt tcaaatcaat ggaacgaata tcgggcaaac aaatgagttg tctattcaaa
    20401 aagcagtaga tttcttctca aacttaacgt tatctgaaca agagaaagta attgccaaac
    20461 cgattttaaa agaagtaaat gacagacttt cattcttgga aaatgtggga ctagactatc
    20521 taactttgag tcgcgcttcc ggaacattat ctgggggaga agcgcagcga atcagattgg
    20581 ctacacaaat tggatcgaat ctttctggag ttttgtatat tttagatgaa ccatcgatcg
    20641 gattgcatca acgcgacaac gatcgactga ttggctcatt aaagaaaatg cgtgatcttg
    20701 gcaacaccct cgttgtagtc gaacatgatg aagatacgat gtgggcagca gattatttga
    20761 ttgacgtcgg acctggggcc ggagaacaag gcggacaaat cgtggctgca ggcactcctg
    20821 aagaagtagc taatgatgaa aattctttga cagggaaata tctttcaggg aaaaaatcaa
    20881 tccctgtacc aaaagaacgc cgtaaaggta atgggaaagc aatcaagatc actggtgctt
    20941 cagaaaacaa tctgaaaaat attagtgttg aatttccatt aggagaattt gtagcagtca
    21001 caggtgtgtc tggttctgga aagagtacat tggtcaatag tatcttaaag aaatcgttag
    21061 cgcaaaaatt aaataagaat tctgctaagc caggtaaatt caagacaatt tccggctacg
    21121 aaagtatcga aaagatcatc gatatcgatc aaagcccaat cggccggacg ccgagaagta
    21181 atccagcgac ttatacaagt gtatttgatg atatccgtgg gttatttgct caaacgaacg
    21241 aggcaaaaat gcggggttat aagaaagggc gttttagttt caacgtaaaa ggcggtcgtt
    21301 gtgaagcttg tcgcggggat ggaattatta agatcgaaat gcactttttg cctgatgtct
    21361 atgttccttg tgaagtatgt catggtaaac gatataattc tgaaacatta gaagtgcatt
    21421 acaaaggaaa aagcattgct gatattttgg aaatgacagt agaggatgct gtagaattct
    21481 tcaagcacat tccaaagatt catcgcaaac tgcaaacgat tgttgatgtt ggcttaggtt
    21541 atgtgacgat ggggcaacca gcaacgacat tgtccggtgg tgaggcacaa cggatgaaac
    21601 ttgccagtga attgcacaaa atctctaatg gaaagaattt ctatatacta gatgaaccaa
    21661 cgacaggact tcatagcgat gacatcgccc gcttgttgca tgtattacaa agattagtag
    21721 atgctggtaa cacagtttta gtgattgaac acaatctaga tgtaatcaaa acagcagatt
    21781 atatcattga tttaggacca gaaggtggag aaggtggagg aacgatcctt gcgactggaa
    21841 caccagaaga aatcattaac gtaaaagaaa gttatacagg tcactatttg aaaaaaataa
    21901 tggtataaag aggatagata gctgagatag ttaaaaaaac ataaaaaaat gaatttttgc
    21961 ttgttttatt aatatcagtg ttctagaatc attacatggt agttctttct acactgattg
    22021 gtatagataa aaacttccta taagttcaat ccgttcaaaa aagaattgag caatcggagg
    22081 actttccttt gattgctttt ttctttatgg tatgatattc cttgtgtagt tggaaaagaa
    22141 aaacaagaga ttatgagtaa gtgagagata atgatgaaca gtattgaaaa tgaagaattt
    22201 atccctatat tattaggaag cgacatgaac gtttatggta tggcacgttc ttttaatgaa
    22261 gcatacggca aaatctgcca agcatatgct tcggatcagt tagcccctac ccgctacagt
    22321 aaaattgtca atgtagaagt tattccagga tttgataaag accctgtatt tatcgagacg
    22381 atgcttcgtt tggcaaaaga aagatattct gataagagta aaaaatatct tttgattgct
    22441 tgtggtgatg gatatgcaga attgatctcc caacataaac aagagctgtc agaatatttt
    22501 atctgtccat atattgatta ttctttattt gaaaggctga tcaataaagt aagcttttat
    22561 gaagtttgtg aagaatatga tcttccgtat cctaaaacat tgatcgtcag agaagaaatg
    22621 ttagtaaatg gacatttgga acaggaattg ccttttgaat tcccagttgc tttgaaacct
    22681 gcaaacagtg tggagtatct ttctgtccaa tttgaaggaa gaaaaaaagc ttttatttta
    22741 gagactagag aagagttcga tttaatttta ggccggatat acgaagccgg ttataaaagt
    22801 gaaatgattg tacaagattt tatcccgggt gatgatagta atatgcgtgt gctaaatgcg
    22861 tatgtagatg aagatcatca agttcggatg atgtgccttg gtcatccact attagaagat
    22921 cctacaccag catcgattgg taattacgtt gtgatcatgc cagattataa cgaaaaaatc
    22981 tatcaaacca ttaaggcatt tttggaaaaa atcgaatata caggctttgc caatttcgat
    23041 atgaagtatg atcctagaga tggagaatat aaattatttg aaatcaattt gagacaaggt
    23101 cgtagcagtt tctttgtgac attgaacggc ttgaatctgg ctcgttttgt cacagaagat
    23161 cgagtgttca acaaaccctt tgttgaaacg acctatggaa cgaatcaatc agataaagca
    23221 agattatgga tgggtgtgcc caaaaaaatc tttttagaat atgctcggga aaatgaagac
    23281 aaaaaactag ctgagcaaat gatcaaagaa aatcgttacg gtactactgt attttatgaa
    23341 aaagaccgat caatcaagcg ctggttgttg atgaaatata tgttccataa ctatattcca
    23401 agattcaaaa agtattttca tgtgaaagaa ggctagttca tggagaattt tttcagtatt
    23461 ttaggcggaa tgggcacgat ggcgacagaa agttttgttc gcttgatcaa ccaccgaacg
    23521 aaagctacaa aagatcaaga atatttgaat tatgtcttat tcaatcatgc aacagttcct
    23581 gatcgtacag cttatatttt agatcgatca gaagaaaatc caatgccgtt tctgctggat
    23641 gatattgaga aacaaaattt attgcgacca aacttcattg tgttgacttg taacaccgca
    23701 cactactttt ttgaagagtt acaagcggca acggatattc ctatcttgca tatgccaaga
    23761 gaagcagcaa atgaacttgt ccgtcagcat acgacaggga gagtagcgat tctaggaaca
    23821 gaaggaagta tgaaagctgg aatctatgaa cgcgaagtca aaaatcttgg tttcgaaaca
    23881 gtgattcctg atactgcgct tcaagaaaaa atcaattacc tgatctatca tgagatcaag
    23941 gaatcggatt atttgaatca agagctctat tacgaaatct tagaggaagc ggtagagcgc
    24001 ctaaactgtg aaaaagtcat cctaggttgc acagaattat ctttgatgca tgaatttgct
    24061 gaagataatc attacccagt gatcgatgct caatctattt tagcggatcg aacgatcgaa
    24121 cgtgcattag ctgaaagaag cgaggcattg gatacagcat cggaaaagta aaaaaattgg
    24181 atttggggca aatatcctaa aagatatttg gtccaaatct ttttgtaaaa gaaaaagaaa
    24241 actggtaatg atacgcccgg gatgatataa ttttattatg cacaatgtga gaggggttcg
    24301 taaatatgac agataatttg caattagtca tcataacagg tatgagtggt gcagggaaaa
    24361 cagtagctat ccaaagtttt gaagatatgg gctatttttg tatcgataat atgccgcctc
    24421 gattgattcc aaaattctgg gaattgatca aagaatcagg taaagtcaca aaaatggctt
    24481 taggagtgga tttgcgttct cgttccttct ttgaagaaat ccaaaacatg ctgatcgaaa
    24541 tcgaaaatac gaacttcatc gacacttcta tcttattttt agatgcttca gacgaagaac
    24601 tagtggctcg ctacaaagaa acaagacgag cacatccaat ggcgatggac ggtttgatca
    24661 ctgaagggat acgtaaagaa cgggcgatac tagacgactt gaaagcccaa gcttccgtga
    24721 tcattgatac gacaacattg acaccacgac aattacgtga aaaaatcaat gagtcattca
    24781 aatcaaaggg agaccaagga tttcggatcg aatttgtatc atttggtttt aaatacgggt
    24841 tgccgatcga ttcggatatt gtgatggatg tgcgtttttt gcccaaccct cattatatcc
    24901 cggaactaag accattgacc ggaaaagatc agccagtcta tgattatgtg atgtcctttg
    24961 atgaaacgca atcattctac cataaatttt tggatcttct ggaaactgta ttgcctggat
    25021 acattaaaga aggaaaaagc agcttgacag ttgcaatcgg ctgtacaggc ggtcaacacc
    25081 gttctgtggc attgactgaa cgtttggcaa atgctttagg gaaaaactat aaagtcaatg
    25141 tgacacatcg ggacaaggat aaaaggaaag agacggtgaa ccggtcgtga aaatgaaaac
    25201 ctaccggata agaaaaccaa agatcgtagt ggtcggcggt ggcactggtc tgccagttat
    25261 cctgaaaagt ttacgaaatc aaggagcaga tatcacagca gtagtgactg ttgcagatga
    25321 tggtggaagc agcggtgcaa tcagagaatc gatcgctatg gctcctcctg gtgacttgag
    25381 aaatgtctta gtggcgttat cggatatgcc acaattctat gaagatattt tccaataccg
    25441 tttcaaaaag gaagatcagt ttttagccaa tcatacgatc ggtaatctga tcattgccgc
    25501 agtttccgag atgcggggaa gcacttatga ggcgattcaa ttattagcaa aaatgatgca
    25561 tgtagatgga catgtttatc cttcttcaga aactcctttg accttgcatg ctgtttttaa
    25621 agacggaacg actgcagtag gagaatctaa aatcgcgatc aaccgtaaaa ccattgaccg
    25681 tgtgtatgtc tgcaacacaa atgataaaag tgaagccaaa gcggctcgaa aagtcgtttc
    25741 agcaattatg gacgccgaca tggtcgtttt gggacccgga agtttattca ccagtatcct
    25801 tccaaattta gtgataccag aaatcggcga agcaatgctc aagacaactg ctgaaaccgt
    25861 ctatatctgt aatatcatga cccaaaaagg ggaaacggaa catttcacag atgccgatca
    25921 tatacgtgtt ttacacaagc atttgaatca gccttttatc gatacagtat tggtcaatac
    25981 ggaaaaagtg cctgaagatt atatggaccc agagatctat gatgagtatc tagtacaagt
    26041 cgcacacgac ttcaacggat tgagaaatga aggatgtcga gtgatttcca ccgacttttt
    26101 agaattgaaa gatggtggtg tcttccacga tggagacaaa gtagtagaag aattgttccg
    26161 tttagttttc ggttcaaaat attaagcaat ttattgttgg agaaaggagg agaataggat
    26221 gtcatttgct gcagatgtga agaaagaact aactggtttg gaagttcatc gagaacatgc
    26281 gaaagcggaa ttagctgctt tgctgcgaat gaacggctct ttaggtattg tgaaccagca
    26341 gtttattttg aacgtccaaa cagaaaatgc tgcaattgcc agacgtatct attctctttt
    26401 gaaagatcat tatcaggtac gaagtgagct actcgttcgt aaaaaaatga aattaaaaaa
    26461 gaacaatgtc tatatcgtcc ggttgaagca aggcacaaaa gatgtgttga tggatcttga
    26521 tatcatggat ggtatgatgt tcaatggaca cgtttcggac gagattatgg gaaattcgca
    26581 aaaaatgcgt tcttacttac gtggtgcttt tatggcctca ggttcagtca ataatccgga
    26641 aacgagtcgt tatcatttgg aaatattttc tatttatgaa cagcataacc aagacatttg
    26701 cgatatgtta aattattacg gtctacatgc tcgaacgctt gaacggcgca atggctatat
    26761 ttcgtattta aaaggagcag aaaaaattgc tgatttctta acattgattg gtgcaaccaa
    26821 ctcaatgctc cgatttgaag atgttcgaat cgtacgggat atgagaaatt cggtcaatcg
    26881 tctagtcaat tgtgagacag caaatctgaa caagacgatt gatgcggctt ctaaacaaat
    26941 cgaaaacatc gaattgatcg aagcaaaggt cggtctacat gcccttcctg aaaaacttca
    27001 ggaaatcgca gaacttcggc ttcaacatcc agaggtcagc ttgaaagaat taggggaaat
    27061 gattccctca ggtgcaatat caaaatcggg aattaatcac cgaattcgca aaataaatga
    27121 atttgcggaa aaactgcgtg aagaagcagt ttaatccaaa gaaaaaactg atacatgaag
    27181 caggagatgc gaatgtatca gtttttttta aaagctatac ttgcttttct tccgtcaaac
    27241 tataattcca actttactgg agtaacataa tgttgaaagg cttctattgt tttttaatac
    27301 aatcgtataa aaagcgggga gacaactgaa tgaagatttt agttttatac ataaactttt
    27361 gcttaatata gaagtcctga tatagatagg atcaagtatt tatctataac tggagattaa
    27421 ttaaaaactg gaaggaactg ctcgatcaac cttgagaact gtttttctta cttctggtca
    27481 agattctcgt ggttggtgga taaggatggt tgataagttc attggattag ctagtcgaaa
    27541 acaaccaggt gtaattaatg tagaagtttt aacaagggga tggagtgatt tattcagtga
    27601 taatcataag ttcataaata gtaattggga tgtatggttg gtatacgtta tacctgaact
    27661 tgaactatca agatttggtt tagaatttga gaatcgatgt ttataaaggg agggcaaaaa
    27721 atgtgctttt ttacaacttt tactatcatt atgattgcag tactttttat ttttctagat
    27781 atagcaaagc gaaatacagc atttttatta tatcgggttt tacttcgagc aggtctcata
    27841 acatttatat cgatcgttgg attttttcta ttcacagtta ttgtatttat ttggagaact
    27901 acagcaccac cattgccaga gattacatat ggagaatttc cgtttagtct tgaatatgaa
    27961 atagatgagg aaagaatttt gattgaagat acggtgattg cagaatttat aggaagtttt
    28021 agagggaatg tgacaactca acctagacga agttggagta taaaactttt aaataatagt
    28081 ggagagttga aagcatttca ttatgaattc ttaataatag aaagtgaaga tgtaacaatc
    28141 actttaagta gtggctctgc tggatatttt atgaatgatg gtggaagcaa gccacagctc
    28201 acagtccgtg atcgtattgc aggttttatg catttttctc actatgactt agaagaagct
    28261 cgtaaaatac ttgcagaata tgggatcaca ttaatcaatt gggaatatgc gccaccgata
    28321 agaaattttt tcaatgatta ttattagtct tataaaaaac agaatgtaaa atttatgtgc
    28381 gcgagtattt agttttccat tttttgtttg atagatatat agcattgttg aagcatggga
    28441 tagtggtgcc aattttatca atgaggttgg tcaggcagtt aacataattg gtgatgctat
    28501 aaatccattt aattggaatt ggaggaatta ggtgtggaaa cagtgagatt atggatattc
    28561 atgaaaaatt ttcgttcggc tttgagatat gttattctgg aatcaaaatc aggttattat
    28621 ctgattgaca cagatcacta tactttttgg ggaggctacc tttttccgat ttttaattgg
    28681 ataatccccc ataaggttat gaaaattaac ttgcctgcag aagaaataaa tagattaata
    28741 ctcaacaaag atttacaaag gaaaagagag aaagaacatt ctaatgttgc ttggataggt
    28801 ccagcatttg cagtagtgac ttcttcaatt gtcggtccta tgctagagag tatttatagt
    28861 gatttttcta ttggaatacg ttatttattt gttactttaa gtatagctgt tcttttgtgc
    28921 ataaagggtt atgttagcaa gaagaataaa gatattttaa cactaatcgg tgtaaacaat
    28981 ttatctagta ctaaaattat actgtttcct gaatctataa aagaaggatc aaggttgttg
    29041 ataattttta taatgcttat actgttttct gttttatttg gggtgatgtt tataga
//
LOCUS       DAFLVO010000035        27812 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.035, whole genome shotgun sequence.
ACCESSION   DAFLVO010000035 DAFLVO010000000
VERSION     DAFLVO010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27812
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.035"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(547..909)
                     /locus_tag="L1U99_001558"
     CDS             complement(547..909)
                     /locus_tag="L1U99_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212104.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(983..1363)
                     /locus_tag="L1U99_001559"
     CDS             complement(983..1363)
                     /locus_tag="L1U99_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBN1212105.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1427..2620
                     /locus_tag="L1U99_001560"
     CDS             1427..2620
                     /locus_tag="L1U99_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBN1212106.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            complement(2697..3281)
                     /locus_tag="L1U99_001561"
     CDS             complement(2697..3281)
                     /locus_tag="L1U99_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBN1212107.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3482..4480
                     /locus_tag="L1U99_001562"
     CDS             3482..4480
                     /locus_tag="L1U99_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBN1212108.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4592..5101
                     /locus_tag="L1U99_001563"
     CDS             4592..5101
                     /locus_tag="L1U99_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HBN1212109.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(5131..5790)
                     /locus_tag="L1U99_001564"
     CDS             complement(5131..5790)
                     /locus_tag="L1U99_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBN1212110.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5792..6556)
                     /locus_tag="L1U99_001565"
     CDS             complement(5792..6556)
                     /locus_tag="L1U99_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HBN1212111.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6564..7241)
                     /locus_tag="L1U99_001566"
     CDS             complement(6564..7241)
                     /locus_tag="L1U99_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HBN1212112.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(7278..8663)
                     /locus_tag="L1U99_001567"
     CDS             complement(7278..8663)
                     /locus_tag="L1U99_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBN1212113.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSCLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8873..8957)
                     /gene="ffs"
                     /locus_tag="L1U99_001568"
     ncRNA           complement(8873..8957)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="L1U99_001568"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(8980..9495)
                     /gene="tadA"
                     /locus_tag="L1U99_001569"
     CDS             complement(8980..9495)
                     /gene="tadA"
                     /locus_tag="L1U99_001569"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HBN1212114.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9601..10458
                     /locus_tag="L1U99_001570"
     CDS             9601..10458
                     /locus_tag="L1U99_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1212115.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10539..10874)
                     /locus_tag="L1U99_001571"
     CDS             complement(10539..10874)
                     /locus_tag="L1U99_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212116.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(10941..12311)
                     /locus_tag="L1U99_001572"
     CDS             complement(10941..12311)
                     /locus_tag="L1U99_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBN1212117.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(12389..12925)
                     /locus_tag="L1U99_001573"
     CDS             complement(12389..12925)
                     /locus_tag="L1U99_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1212118.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            13234..14715
                     /locus_tag="L1U99_001574"
     CDS             13234..14715
                     /locus_tag="L1U99_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1212119.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLIKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(14818..15525)
                     /locus_tag="L1U99_001575"
     CDS             complement(14818..15525)
                     /locus_tag="L1U99_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBN1212120.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(15604..15942)
                     /locus_tag="L1U99_001576"
     CDS             complement(15604..15942)
                     /locus_tag="L1U99_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBN1212121.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(16053..17015)
                     /locus_tag="L1U99_001577"
     CDS             complement(16053..17015)
                     /locus_tag="L1U99_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HBN1212122.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(17030..18361)
                     /locus_tag="L1U99_001578"
     CDS             complement(17030..18361)
                     /locus_tag="L1U99_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBN1212123.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(18369..19049)
                     /locus_tag="L1U99_001579"
     CDS             complement(18369..19049)
                     /locus_tag="L1U99_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBN1212124.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(19268..19747)
                     /locus_tag="L1U99_001580"
     CDS             complement(19268..19747)
                     /locus_tag="L1U99_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HBN1212125.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(19874..21553)
                     /locus_tag="L1U99_001581"
     CDS             complement(19874..21553)
                     /locus_tag="L1U99_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBN1212126.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            22101..23603
                     /locus_tag="L1U99_001582"
     CDS             22101..23603
                     /locus_tag="L1U99_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1212127.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            23616..24278
                     /locus_tag="L1U99_001583"
     CDS             23616..24278
                     /locus_tag="L1U99_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1212128.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(24379..24582)
                     /locus_tag="L1U99_001584"
     CDS             complement(24379..24582)
                     /locus_tag="L1U99_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBN1212129.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(24693..25877)
                     /gene="iadA"
                     /locus_tag="L1U99_001585"
     CDS             complement(24693..25877)
                     /gene="iadA"
                     /locus_tag="L1U99_001585"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBN1212130.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(26034..27773)
                     /gene="yfcC"
                     /locus_tag="L1U99_001586"
     CDS             complement(26034..27773)
                     /gene="yfcC"
                     /locus_tag="L1U99_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBN1212131.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
BASE COUNT         8258 a         5803 c         4706 g         9045 t
ORIGIN      
        1 gagtgtttcc cgattcgttt ttggctgccg tagcaacttt tatatcatat cagagagaca
       61 agcgattgtc aactcttttt taaaagtttt tttcgatttc gtttttcgaa atctttcagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcgt
      241 tagtaacatg tcaataacta ttttttaaat tttttagaaa tgtgatataa catccacttc
      301 agaatcaacg ctgttaaatt tatcatgtat ttcttccttg gtcaactata aattaagcat
      361 tactttgtga aatgattttt cgatcaatta ttattattcg ttatacaacc gttttcaaca
      421 tattttgaaa ataaaatgca ctaaaaaact atctttagca gaacatttca ttgtattttt
      481 tggaccaaac aataaaaaaa gaagtttgaa aaaaattcaa acttctttgt tcgcttaatc
      541 tgtattttag aagaaaggca ctccctctac ttcgtaagtt ccaagaacag agcgcatttg
      601 acctggttct tcccaaatat atccttcgcc taattcttct ctttgattct tttgttcagt
      661 ttcaaagaca aacaacggaa cattttcctc tttaatatgt gtatttgtca attccatcaa
      721 actaatcttg ctaacatcga tatgaactat ttcttttaag aaattaagta tattcgctaa
      781 accagtcttt ccttcagaaa gttccgctaa cgcaaattcc aacttgtcat caattgaatg
      841 gaccaaaaat tttttagtac catcctccaa atgcaacata attgtaccag caactctttt
      901 gcttgccaaa atttccacct cgatcaactt gttctatggc ttacataaaa attctagcac
      961 attttcagaa aaaatacact ttttatttct tattttcttt ccgttctagt tcagataatg
     1021 cttcttctat ccaaataggt aactgctccg caatagtggt aaatccgatc ttacgatttt
     1081 tattcgtgaa ataccttttt ctgcgatatg gaacagctgg atttgttttt tctaacgttc
     1141 ttaaagataa actgattttt ttggaatatt catcaatgtc gatgatctga actgttactg
     1201 gctgtccgac ttttaacaat gaatggatat ttttcgtata accggattgt acttctgaaa
     1261 catgaataag tccttgcgtc tcgttatcaa gagaaacgaa tgcgccataa ggctgtatcc
     1321 ctgtcacttt tccttcaatt atttgtccaa ttttataagt catctacttc cctctcttcg
     1381 catttatcat tatactgtaa atagctcaaa aaaagaagcg acgaaaatga ctggaggtct
     1441 taagatgatc gaatttgata aacagatttc aagaaaagat acagaaagtg taaaatggga
     1501 cgcaattgct gagacatatc aaatggatga cttacttcct ttgtgggtag cagatatgga
     1561 cttcttgtct cccggtgggg tagctaaagc gtttagtgaa tacatcaaac atggaatctt
     1621 tggttatgcc actctgtctg ataaactata tcaggctatc attcattggg aacgccaaca
     1681 ccatgctgtg gagttgacga aagaaaatat cgtttttaca agtggtgtgt taaccagttt
     1741 agctgcagca gtacaaactt ttacaaaacc aggcgattct attttgattc atgacccagt
     1801 ttatcctcca ttttcctcta ttatagaaac aaatcaacgt cacatcgttc gaagctcttt
     1861 gctagaaaaa aataatcatt tcatcatgga cttgtctgac atggagaaaa aaatcgaaga
     1921 aaacaatgta aaagcaatga ttttatgcaa tcctcacaat cctggagggc gtgtttggag
     1981 caaagaagaa ttgaaacagt taagcgaatt gtgtttaaaa catcaagtga ttctgtttag
     2041 tgacgagatc catcaagatt taactttatt cgatcataca tttacttcca tgctaacgat
     2101 tgatcctaat ttagatgatc tactagttgc ttttacttcc gcaaccaaga ctttcaatct
     2161 agctgcaatc aaaaattcaa tggtatttat caaaaatcca gagatgaaag ctgattttga
     2221 aaaacattta gtgatgaacc aacagcacga aatcaacact tttggactga ttggaaccca
     2281 agcggcttat gagacgggtg gagaatggtt aagccaactg attccttatc tagaaaaaaa
     2341 tgttcaaaca gttaatcagt tttttgaaca gtatcttccg aaagtgagaa taatgaaccc
     2401 tgaaggaact tacttaatgt ggttagattt taccgcctat atttcagacg accaagaatt
     2461 ggagaacact cttgttcgga aaggaaaagt cgtattaaat cctggcatca cgtttggtcc
     2521 ttccggtcat gggcatatgc gcttgaatat tgcttgtcca gaagaaactt tactggaagg
     2581 acttaatcga atcaagtatg ctttagagac aatcgattaa atcatttatt caaaataaaa
     2641 ggacgagacc ttactaggtt tcgtcctttt tcataattac tccgtaccat accaaactat
     2701 tctgaaattt caattgtttc aatcactaca tcatgtacag gtcggtcttg tggaccacgt
     2761 tgtacatttg cgatttcatc tactgtgtcc atcccttcta gtacatgtcc aaagactgta
     2821 tgtcggaaat ctagccaagg agttccgcca cctttatacg cttcaatgat ttctgatggg
     2881 aatccagcac cttctagttg tccaagcata ttagctggca catttgtgtt atttacaata
     2941 aagaattggc ttccgtttgt gtttggacct gaatttgcca tagataaagc tccgcgaagg
     3001 ttgaacagtt cacgactgaa ttcatcttca aaactttcgc cataaatact ttcgccaccc
     3061 attcctgttc cagttggatc gccgccttgg atcatgaaat caggaataac gcggtgaaaa
     3121 atcacgccat cataataacc ttttttggaa agttcaatga aattttgaac cgtcttcggt
     3181 gctagttcag ggaataattg aacagtaatg tcaccacggt ttgttttgat aacagctttt
     3241 ggtccttttt cactttttaa atctagttgt gggaatgcca tattgtttcc tcctaatatt
     3301 tgcatacttc ataataataa taacataata cctaacctct cgtaaaaata ctagatttgt
     3361 tttcttttat ttttcatcac tagatacatt ctataactta ccgtttcgat ttcgaattca
     3421 aacatttttg agaagcattc tcaattaaat tctgatatag tgtgaaaagg gaggaatttt
     3481 tatggaaatc tatgacatta caatcatcgg tgcaggtcct gtagggatgt ttgccgcttt
     3541 ttacgcagga atgcgccaag ctaaaacaaa aatcattgac agtctacctc aacttggtgg
     3601 tcaattagca actttgtatc ccgaaaaata tatttacgat attcctgggt atccagcaat
     3661 aaaagcaagt gaattaatcg atcaattaga aaaacaatta actactttta accatacatt
     3721 ccatttaaaa gaagaagttc tctcgcttac tcgtgaagac gaagttatcg agattactac
     3781 aaataaaggc atccattatt ccaaagcagt cattttagct ttaggaaatg gttcattcca
     3841 gccaagaaaa ttgaatttag ataatgctga atcatttgaa aaccacggat tggattattt
     3901 cgtgaatgat ttgatgaagt atgctggaaa aaaagtcgct attgctggag gtggtgattc
     3961 tgctatcgat tggacgttga tgttagagcc tattgcaagc gaagtttact tgattcatcg
     4021 tcgcccggaa tttcgtgcgc acgaacatag tgtatcacgc ttgaaatctt catctgtcaa
     4081 cttgcttact ccctatctca tcgatggatt atcaggcaat aatggggaac tgacagatat
     4141 ccggttaaaa aaagtgaaaa gtgacgagac gattgatttg atgattgatt ctctgatcgt
     4201 caattatgga ttctcttcta atttagaaca tctttcttct tggggacttg atagtaccag
     4261 aaatgccatt actgtaaaat cagatatgtc tacttctatt ccaggcgttt atgcagctgg
     4321 tgacatctgt acctatgaag gaaaagtgaa actgattgct actgggctcg gtgaagcacc
     4381 tactgcagtg aacaacgctt tacactatat taatccaaag gaacgaactc agcctggtca
     4441 cagcacaagc ttatacgata aaaatcttcg tcctagttga ttttttatat ctctttgcat
     4501 ttcaagttaa acccgaaagc agtttcttgc atttttttca tgttccgtta acatgaaata
     4561 gagaaagaaa aaataaaggg ggagcaataa tatggtcgtc aaaactgaga ctttagaaga
     4621 aaaggcaaga gaactattga aggaacgtgg cgtaactgta gaagatatcg cacaacttgt
     4681 catgttttta caaaaagact atatttctga tttgactttg gcggattgta ctgaaagtgt
     4741 caacagcgtg ctaacaaagc gtgaagtaca taacgccatt atcactggaa tccaattaga
     4801 tatattagca gaaaagaaaa aattgatgag tccgttgcaa catattatcg aagatgacga
     4861 aggcctttac ggtatcgatg agatcctagc cttgtcaatc gtgaatgttt acggtacgat
     4921 cggctttacg aattatggtt atatcgacaa ggtgaaacct ggtattttaa aagaactaaa
     4981 cagccacgat ggcgttcatg tccatacctt cttagatgat atcgtcggag cgatcgccgc
     5041 tgctgctgcc agtcgattag cacacaaaga accagaaaaa agaagtcgcc ttactcaata
     5101 attcaacaaa aaaagaaaga aaacgtctat ttagacgagt tctttctttt ttgtttgttt
     5161 caagctattt tttcctaaga aaagaaaaac agcaaaaaat aattctaata atacaaaaaa
     5221 taagataaag ctatgcatga aaaattcttc tggaagtaca ttgatgattg gatcagtaac
     5281 gggatcgaat aaccagtcat cgttgttgaa aaacgtttca tgaaaaagga taaaaaagcg
     5341 atcaaatcct atcatcatga aaaaaccgaa aacaactggc agtaacatgc cgatttgaaa
     5401 cggacgaatc aaccgccaaa gccgatcatt cttttgcaaa tatttgataa acaaaatact
     5461 cgggatcaaa gtgatgaaaa acacagcata atccactaaa aacaaaattt tcacttcata
     5521 aaagtgatgg gctccgctag cagaaactgg gaaatctggc aagctgagga tggttttgaa
     5581 gggattattg agataattca ttaggtgatc aaaatttttc agtaacgtct cttgatctaa
     5641 agaagtataa tccaaaattt gcaaatgtcc gatatcaaat acgtatagtg gtcgaaagtt
     5701 gatcgtcaca ccaactgcca gactgatcag tgtcagaaat aggctgaaca atccagcata
     5761 ttccatccac tgccatctcg aatttttcat attagaagct ccattcatcc agtgattgtt
     5821 tcacataggt agctgggata ggcaacccag gtacatcttc ttcttttgta aaacctgata
     5881 aaacgagcaa agtatctata ttattgcgta tcccagcttg gatatctgtt tcatagttat
     5941 ctccaaccat gattacttct tctttttgca gccctaatac ttcaacggct ttatccataa
     6001 tgatggcttc tggttttccg atgtagatcg gcggcgtttg ggttgctgtc tctacaaaag
     6061 agatgactga ccctgctcca ggaagaaggc cgcgttcagt aggtatattc ttatctgggt
     6121 tcgttccaat gaaagtagca cctttttgaa tagcaagtgt tgctttaact actttttcat
     6181 aggtcagata attatctaag cctaccacta catagtcagg agcctcttct tcccatgtaa
     6241 atccggcagc taaaatcaag tcaatcaatc ctgcttctcc gataacatag acttttttcc
     6301 cttttccatc tgctttcata aaatcgattg ttgccaaagt agctgtgtag actgtctctg
     6361 gagctacatg aatgtcaaac tcatctgcta gacgattagc tactgtttct ggtgacttag
     6421 tcgtgttatt ggtaacaaac aagaaaggta attttctttt ttgcaattct tccacaaatc
     6481 gtttaccggc cggtatgggt tgtgtcccac gataaatcgt tccgtctaaa tcaattaaat
     6541 atcctttata gtccattcat ccactactct tccctttttc tgatcgtaaa tgctgttttt
     6601 gttttttcta cttgtttagg ttgttcttgt ttttttactt tttcagaggt ttttgctgac
     6661 tctgtttttc gatttttaat aaccggtttt ttgcgattag atgcgactgg tccttttttc
     6721 tcatcgatat acgcacgatt atggtttttt ttcttttttc ggcgctgagt tgtcttttct
     6781 tttttaccgc cgattctctc gatgacaaaa tacgcacaac caaaattgca atattcgtaa
     6841 agatagtctt ccaaggaatc gattcgctga tctggatgcg cccgtcgatt atccgcttgg
     6901 aaaaatcctt ttaggcgtag ttgttcataa ccccaatctc ctacgatata atcatatcgg
     6961 gctagtacat cactgtaacg ttctccaagc ttttctgcat taaatccttc acgataatcg
     7021 gacacaagcc gataatgtct ttcacctatc aaaaaattac tgtcatctaa cagtgtcact
     7081 agctcgcctt tgactttttc tgctttaggc tcctcaacga tttcttccaa agcagctgtc
     7141 agttcttcgg tgactgttgt ttcctgttca gctgatgatt ttttcttagc aatttctgtt
     7201 ttatgctcaa cgttctgctg ttcattttgt tttgcagaca tgcgttcacc acctatcttt
     7261 tttattatac cttgttttta tttgattggg tagtgagctt tcaagtaatc tcctaccaca
     7321 cttcggataa attcagggaa caaaaattca ttttttccag caatctcaat cgttggaaaa
     7381 aatggaacaa acatcaaatg atctacggta gtaaaagtat aatttttatt cagatcgatt
     7441 ggcttgttct tccaaaagac ttgatggtta atagaatcat atgtgattcc attatagacc
     7501 atctgcccaa aaatcttacc gcgaaatccc attcccttca taggatagtt acgtaaaaag
     7561 ttacgatttt tttctatttc taaaactaag cggatcagat catttccacc caatgtgaca
     7621 tttaacaagt gcatcggatg cggcaacgca gtgtgaagct gatcctgatt gacccgccct
     7681 tttggaattt cagttaaaaa cagaccactg tttaatattg ctgcttccgt ctttcctcgt
     7741 tctttcaccg cctcaaaggc tacttggata aacgaatgct cattgaagat atctagactc
     7801 agagaaaatg gcaaatctgc tacttctttt tcttttaata attcatgccc acgttctaga
     7861 caactattta tttcttgttc atcttctgta aaagctgtca ttgtttcggt agggatggct
     7921 ttggctgaat gcttaaggat ttttttctct tcatcgatgg ttaaatggac ttcaccgaca
     7981 tactgcccgt actttccagc ggctgctatt tggacatcat tgattacgtg accttctctg
     8041 aataaatgat gggtgtgcga tcctaaaata acatcaattg ctggtatttc ttttgcaatt
     8101 tggaaatcat cctgaatccc gagatgactc atcaaaacta aaacatccac ttgtgaacgt
     8161 aaatcttcga ctaattctgg caaaatatca taaggattcc gtatgtccca gccattcgga
     8221 ttataagtaa gcggaaatgg agcagtaaat gcaattagtc cgattttcgt ctggtgtttc
     8281 gttgtaatga ttttatatgg tttcgtccat gccggtggct ggagcgtatt tttatcgaat
     8341 aagttatcca ggatgatatc aaactcagca tgatcgtata aatgattcaa ctcttctttg
     8401 gaatttccta cgccttcatt gtttcctatc gtcgctgcat cataaccaac ttcattcatc
     8461 agcaagatat tttcctgtcc attcgttgct tctgacaatg gatgccaacg atccacaaaa
     8521 tcacctagat ctactgcaat cgttgtcgtt ttttctttct tttcgttttc tcgtttacgt
     8581 tgatccaaaa accttctgat ccttggccaa ttttctaaat gagaatgcag atcattcgta
     8641 tgtaaaatca ctattttttc catgtaccct ctcgcctctc tttatcttta tcataccata
     8701 ggcagctttt tcttccattg aaacaagctc tatttcagag tttttcctgc cttgaagcaa
     8761 attgtataag tacaatattc gataaatcag tctggctaaa aaatcaggaa cattcatttt
     8821 tacagtacta taaaaataaa aaaaacagac ccgaaagtct gttgtcgttt cattataatc
     8881 agacacatgg cggaacctgc ttagtgctgc ttccttccag acctgacacg cttcacaagc
     8941 ccaccattgt cctagccttt cggcaaagaa tagtatacct tatttttcat tcgttgacca
     9001 gtcttttttt aatttctttt ttcgctggcg gagctttcgg aaaaagtcag tcaaaatcat
     9061 cccacattcg tcttctaaaa tgccaccttc tacatatgct tggtggttaa accgctcgtc
     9121 ctccaaaaga ttcatcaagg taccggctgt tccgcctttt ggatcatacg cgccgaaata
     9181 aacttctgct acacgagaca aaatcatcgc gccgctgcac ataggacaag gctctaaggt
     9241 aacaaaaagt gcagcatctt ccaagcgcca gcttcccact ttttcacagg cttccttgat
     9301 tgcaagcatt tctgcatgtg tagtagcatc ttgcgtggtt tctctaaggt tatatcctct
     9361 tccaatcact tttccatcca atacaaccac tgctccaatc ggaacttcat gaagcatttc
     9421 tgctttcttt gcttctgcca atgcaaggcg catccatttt tctttttcta ctgcatcaag
     9481 atttgtattt accaattacc cttccctgcc tttgtttttt cttgttttac tttagcatat
     9541 gataaaaagg ctgtaactaa ctttttttct atggtaaaat aaatacaaga ggtgaacaag
     9601 atgaaaatgg ataaattact tgctctttac ccacaagcac agaaaaaaaa ctctccagca
     9661 tcagaagcgg atatcctttc ttttgcaatt gatgatgctt ttatctggat caaacaagat
     9721 tcattatctc aacaagaaac cagccttttg aaagcgttat tccctgtaat caacgatcaa
     9781 aaaaaacacc catggtatca ctatcttttt aaagatgctt cttgtgttca agaaaaaagc
     9841 tttcgtttga tccagcttca cgtcgaatca aaaggagaat tcttaaaaaa agaatggcaa
     9901 gatactattt tggaattatt tcgctattct gctgatttct ttttttatac agacacagat
     9961 gcgctcttag tcgaacaaat aaaccgtgat tatcttgatg ctactgaaat caacggtatt
    10021 tttctatctt tagatgctga ttttgatacg acaacgtctg tattcgttgg ttctttccat
    10081 tcacctggca ccgacctcgt ccctttgttt gctgaagaaa gaaaaatttt tttaacagag
    10141 caaaacaatc tttatactca cagccgtact ttttctatgc aagatgtggc tttacattac
    10201 tatacaaaag atactgtaaa agatagtaag ttgatcaaaa gttacataga actgatcaaa
    10261 caaaatgaaa tggaagtgat cattcaagaa ttatggaatg aattaggcaa tgtcagctct
    10321 gctgcaaaaa cactgtttct tcatcgtaat actctaaaat atcgaatcga aaaatttcaa
    10381 gaacagtctg gtttcaatct aaaaaaagcc aacgatttac tgttttgcta tcttttattg
    10441 cttcatgaac ataattaaag atagattaaa ggggttgtga caataatttt gtcacaaccc
    10501 cttatttcga atgaatagtg ttcaaaagct agtttctctt acatcatttt ttcaacaaaa
    10561 tgcattagcc ggtcttttac atcttcggtt gaatctttga ttgaatcacc ataaacagag
    10621 attttctttt ttcctgattt gatttttgct aacattccca tcaaagaatc caagtcacta
    10681 tctgaaagac catctacgat ttctagtaat ttttcatttc catcaaattt gtcatagacg
    10741 aattttttta ctttcgtccg agtagtcata tgatggatct tttccattac ttttcccgat
    10801 acaacgactg ctgtcgctac actggcagcg gctgctacgc ttaatccgat tgttactttt
    10861 gttgatgttt tcataagtat cagctccttt ttatctatct ccatcatagc atagacaaaa
    10921 aaataaacga actaatccac tcagtgaaat ctcaatcctt tagggaaaaa gttctttact
    10981 gttcctttta cttgtttccc aaatccgaca ggtatcttat ctaatactag caaaacccat
    11041 ccttgattcc catcacgttg aaatgtttct cctgctgtgt aagattgcca ttccttttga
    11101 gtgatcggca agcaaggtat attctctatc ttttttgtag caagcgctaa tgcatagcta
    11161 ggttcaaatc gattcttttt gaaatctcct aaatgcaaac ctgtacgtac gacttttaaa
    11221 ccatcgagag aaggggctaa ctcaggaact tcccaaagat ggtcgttgaa cactaaaagt
    11281 cttccagtag cttcataatg aaaatcattt gaaaactccg tccagagttt ttcctgctct
    11341 tttgtcattt gcactttact tttttttcgt gtcttctttt ctttatgcat ctgattttgt
    11401 ccatgaaaag tcagctttgc aacaaaatgt ccttcaccct gatctttatg aggccatata
    11461 cgtattgttt tttccaaacc agctacgctt ccccattcag aacgtcctga actaacggat
    11521 tgagtcaaag gaatctcctc aatcgttact ggataatttt ctacaagcca gctaatgatc
    11581 tcttcatttt cttctggtgc aaacgtacaa gtcgaataaa tcagttgtcc tttatttttt
    11641 agcattttta ttgctgaaga caaaatctct tgctgacgtt tttgacagta tagcggagat
    11701 tcttctgtcc actcttttat tgcatttgga tcttttcgga acattccttc tcctgaacaa
    11761 ggagcatcaa ccacgatccg atcaaaaaag cccgaaaaat gagggacaag ttctgcgggt
    11821 gcatgatttg tcactattgc gttcgaaact ccccatcgtt ctatattttc tgataaaatc
    11881 ttcgcacgtt tcggaaagat ctcattcgtc actaataacc ctttcccctt catttgagca
    11941 gctaattggg ttgatttacc accgggagcc gcacacaaat ccaaaacttt ttcaccgggt
    12001 tttgctgcag cagctgttcc aacgatcatt gcacttggtt cttggctata ttcataccca
    12061 gcttgatgga ggaaagactt tccattgaca gtgccaagaa atccctcatt gctgtaggga
    12121 gcgggttgta attcttcgct atggtaagtt tggaccatgt ccaatcctgc cggttttagt
    12181 ggattccacc gaaatccttt tttcacgctt ccttgttcaa gcgcagaaaa aaaatcggat
    12241 gcttcttcgc ctaaaagaag acgatatttt ttgataaatt gctgtggtaa cgttgtcgct
    12301 tcctccttca ttccaatgtt tcgttagaca ttttacaatc ttttttacga aaaataaagg
    12361 tggctgatct actttttcat gttgctgcct aaggtgactg ttcctttaag atattttcca
    12421 agtattcatc cgtcacctcg tttttatccc aaacagcgtt catcatttca agaaaatctt
    12481 gagaagaatc atctgagcgc aaacttccca atgcattaag ccataccaat tcaagcgact
    12541 tttcttcttt gatcttcgtg tgacctttga catatgagaa aaatggccgc ttaaatagcg
    12601 aatccatgtc taaatcagat tttgcaatga tttcacgaat actttcatgg atagaaaaaa
    12661 aatctttcaa taagtagaca atgcttaaaa catcatcgga actgcattca gctaagtagt
    12721 tttcaaaata aacagtgatt tcttctaata tcttctcttt taacccgctg attgatttga
    12781 aatgtgtata aatcgggtat gtagaacaac cgcagaactc tgctaactct cttgcagtaa
    12841 ttgacttcat tccatattct tccacgtata ccatactttt gaacagcaaa tattctttac
    12901 tataatttgt tactctcccc atcattctta cctccgtctc ttttcatcta cccataaata
    12961 aataacataa ataattctaa aaatattatt gataattatc aaaacatatt tagttatatc
    13021 cattaaaaat caatttttcc gccttaaaaa caagaatatc ttgacaaaat accctaggaa
    13081 ataaacaata gaataaacaa ggtaacaaaa aaattaaata acgttatata aaaaagaagg
    13141 cgacactctg tgagaataac acagactgaa atgactttcc actcacagtt tttgtctaac
    13201 tatatacaaa aacagaataa aaaggaggta tttatgctaa ttgaagcaag aaaaaaagag
    13261 ttacttgttc tacaaatggt cattcaaaaa aataattgtt ctttacaaga attatccaat
    13321 gacttacata ttccaaaacg gacaatcaaa gaactgatcc gaaaaataaa tgtatcactc
    13381 aagcaatttt tattgattga tgaatttatt tattctaatc ataaaggaga gatccaaacc
    13441 aaagaaaccg atcaaactaa aaagttagct gttttttcta agttaaaatt atgctaccta
    13501 aaagaatcca atcgttttaa ctatttgatg ttactaatca attatccaca aactgctgta
    13561 ccaaaaaaat atttacttga acaactttat atatcgccct cctatctcga aaaactgaca
    13621 aaacagctca atcattcctt aataaaattc catttacgga tcctatctgt aaaaaattgc
    13681 tgtactcttg aaggaaatga gttatctatc cgtctctatc tttacttttt tctttcagat
    13741 acatttggag gtaacgattg gccattttcc tcacttgaat taaatgcact aaaaatgaac
    13801 agtacagatg agcaaataga aaaaatttca aaacaagaaa aaaatatcta cttgctgtta
    13861 actttattca tattacgaaa caaacaacag gcatattttc caaaaacttc ttctgaaatc
    13921 actgaattga tggacttatt gcagcataca catgattatt cagaatactt tacttctttt
    13981 tcagtgagtc gcccttgtga agagacagaa acagagagag cctactttaa ttattttttc
    14041 tattgttttt ttccaaatca aatctctttt cgacaaaaac aggagattgg ttttttattt
    14101 tccacaagca aaaaccttat ttgtcgacaa gtcggtcaat tgatgactta cttaactcaa
    14161 cagtttcctc tcaaccattt agaaaataaa ataccaattt atttttattt tcttgtgttg
    14221 gcagttgttt ttttcgaact gttgggtgaa tccagcagta gtttttctac actttgcttt
    14281 ccagaagcca cgtccaatca ttctagttct tttatacagg aaaagaaatt aagagaaaaa
    14341 atcgatacaa ttttttcaaa aaatggggaa agaaaccaaa tcagtcaata ccttagtcaa
    14401 ttgatccaac acttactaca aacagaaacg aaagagcagt tactcatcca tttgcagata
    14461 accaaacagt ttacaggaaa ttatcatctt caaagccatt tgcagcagtt atttcgcaaa
    14521 gatgctgtta aaattaccgc atattcagaa catgctgatt tgatcattac agatcagcat
    14581 gagaaaattt cagatgaaac ggagactttc tatctggata caacgcacaa tacagtgtta
    14641 tttggcaagt taataaaagc ggttcatgaa ctgtatatga aaaaaggtta tgagaacaaa
    14701 acaaagagga tgtgacaaaa ttcttgtcac atcctcttat tccaaataaa tggtattcaa
    14761 tcagctaact ctcggtatta gctcagatca aagcgctgat ttcacaactt ctttatttta
    14821 atctcttcgg ttgccgccga acaataagat caagcgcaac agctgcagga atgtcgaaag
    14881 cgctgctgca acataagtca gtgctgctgc aaataatacg tgtcttgcca tcggtacttc
    14941 ttcttccgtc agtagtccgc cttcactcaa aatttggatt gctcgccgag acgcgttaaa
    15001 ttcgactggt aatgtcacca attggaaaag taatgctaaa gaaaaagcga aaatcccgat
    15061 attgattaac gtagagttcc agctaagcaa tacacctacc ataatcaagg ggaacgaaat
    15121 catcgaacca aagttagctg ctggaacaag tgctgcacga atcttcaatg ggacataacc
    15181 cgaagcatct tgtaccgcat gtccgcattc atgagctgct acacctatcg cagcaactga
    15241 agtagactgt gcagttgctt gagacaaact caacatctta ttacctgaat tgtagttatc
    15301 tgtgagatct ccggcaattt gttgaacacc gacattattt atctgttgac tttgtaatat
    15361 atattgtgct gcttgtgtac cagtcacatt gtttttgctt ctcacttgat cgtattttcg
    15421 gaaagtacta ttgacgtacg ctgacgcaat tccggaaata actaatccaa gaatgaccaa
    15481 aagaaatgtc ggatctaaaa aaccatacat tccataacca tacattttcg tttcactcct
    15541 tttcgtttac tttattttat cattagtagt aggaaaagaa tgtgaaaaga ccttgaatat
    15601 tctttaattc tttttcacaa attccgattt cagtttcatc ggtccaaatc cttctacctt
    15661 gcaatcgata ttatgatcgc cttctactaa acggatgttc ttgacttttg ttccttgttt
    15721 aatggcacct gacgcacctt ttactttcaa gtctttaatc actgtcacgc tatcgccctc
    15781 taacagacgg tttccatttg catctaatac cactaatccg tcttctatga cagtttcttg
    15841 ttcttctttg ttccattcgt tcccgcattc tgggcaaatc aacaagcctc gatcttcata
    15901 tgtgtactct gagccacatt ctgggcaatt tggtaatgtc atcttctttc tcctttaaaa
    15961 tctttagtga gcactattgt aacggaaaaa gaagatcttg aaaagataca tttgtgattt
    16021 ttactacaaa aggcacgttt tcgaacgaag tatcattctg tttttctgct cttatacgat
    16081 tggcatatat cttggatctc tttatagatt tcctctactt ctgctaaatc ttttgcattc
    16141 gcaccacttg ctaatggatg gcctcctcca tgatggcgtt tagccaattc attgatgatc
    16201 ggccccttag aacgtaaacg tacgcggtaa taccctgaag gctgctgaac aaaaatcccc
    16261 caagccagca cttcgtcaat cactccagga agtgaaacga tcgaagctgt ctctgaatca
    16321 tcgattccat atttatcaag aatttcttgc ggaaggatta ttcttcctgc accattttca
    16381 tccacctgga tattttgata aagataaccg gaaagtttag cgactttcat cggcatttgt
    16441 tcaatctctc tgttcaaagc acttgcatca aatggataat ttctcaatat cgaagcaatc
    16501 tctaatgtac gggacgtcgt ggagggatac aaaaagcgcc ctgtatctcc gacgattcct
    16561 gcataaagta accgtgcagc cttaacgttc atctttaaag attcaggaaa catcaaagca
    16621 aattctgcaa tcatctcact acagctactt gcttttgtat ttacccacac aagatctcca
    16681 taagggtcat cattgggatg atggtcgatt ttgatcagtt tttctgccaa ctgatatctt
    16741 tgatcactga ttctgggtga attagctgta tcagtcacga tgactagcgc tccttggtag
    16801 aagacatctt caacttcttg catttctgct aaaaagcgaa gcccttcaat cgtttcacct
    16861 acttgacgta tttctttttc tgggaaactt tcccgtaata gttcggctaa tcctacttgt
    16921 gatcctaatg catcaggatc agggcgcaaa tgcctgtgga taatgatttt atcgtatttt
    16981 tttattgtat ctactatttc ttgctgtact gtcatttcac tcctgctttc taagaacgtt
    17041 ccattacttg acaaacaacg attgctttgg aaacgatggt gttttcaata aacacttcga
    17101 tatccagttt agcggaacgt ctgccgattt ccaatacacg tggacgaatg tctaattcgc
    17161 tttccaattg gatcagccgc aaataatgta ggttcacttg ttcaatcaag atatttcgtt
    17221 tttggttcat caccattgtt ttttgtgcga catcagaaat gatttcgcta agtacgccaa
    17281 aagaaatggt tccaacgcca ttgaccattt gtggtgctac tacgaatttg aacttagggt
    17341 tttccaaacg atttccttca cggtcagtat caatcgtatg gatatttcca gatatctgat
    17401 ccgaaatcgt atctgcaatc tgcggttgtc gctggacaag ctgcatcgct ttcattacat
    17461 cttgccgggt aatcaagcct tccaatgtca agtcatcgga aacgaccggc atgacttcta
    17521 gcccatccca gatcatttga tggctaacag aggcaatact cattgttttc tttacactga
    17581 ttggttcttt cgtcatcacc cgatcgatga tctggtttgg cgatttccct aaaacatctt
    17641 ttgccgtaac aatccccatc aaacgatgat ggcggttgac gactggaaaa cgcgaatgct
    17701 gcgtttcttc tgacaaacgc tgataatcag aaatcgtatc tgtctgctgc aaataatgag
    17761 tcttttcagc tggcatatag atatcactga caagcatgat atcttttttg atcaattggt
    17821 cgcttaacgc tcggttgatc atggttgcga ctgtaaatgt atcataagag gtgcgtaaga
    17881 tcggcatttc aagatcatca gctagctttg caatctcagc agtcgtattg aatcctcctg
    17941 tgatcaatac tgcggcgcca tcttccaatg ctaatttttg gacttccgcc cggttgccga
    18001 cgatcattag tgatcctggc gtaatatagc gttccatggc atgtttagtc atcgcgccga
    18061 tgacgaattt attcaagacc ttgtctaatc ctgccgcccc gcctaaaacg tccccttcaa
    18121 tgatcctgac gacctcgcca aatgtcaaac gttcaatatg tttttttaat ttgcgttcga
    18181 tacggatggt ccctactcgt tgaattgttg aaactagtcc gacattttct gcatctttga
    18241 ttgcacggta cgctgttcct tcactgacat tcaattcttt tgcgatgctt cttacagaaa
    18301 ttcgattgcc aacaggtaaa ctttcaatat attctaaaat caaatcatgt tttgtcgcca
    18361 ttttctgcct acacttccag cgtttccgag acgctcatta tttttccttc actatcttcc
    18421 agtaactcta caaaagattc gggatcttgt tcaatgacag ggaaagtatt gtaatggatt
    18481 ggaactactt tcttggcacg aattgtttgc gcagcctttg ctgcatcttc tggccccatc
    18541 gtatagttat cgccaatcgg caagaaagcg acatcaatat cgaattcttc tgcaagcaat
    18601 cctagatcac tgaaataagc agtatcccct gcatgataaa tcgtttttcc ttctgcttga
    18661 ataataattc cgctaggctc gcccatatac tgaacgatac cgtctacttc atagcttgaa
    18721 ctatgctgtg catgtacgaa ttttaccacg ccgaatggaa acgcatgttt tccaccgata
    18781 ttcataccga atgaatctac tcctctgctg ttcgcataat cagcaatctc aacaatactg
    18841 ataattgtgg cttgattttc ttttgcaata ggaatcatat ctcctatgtg gtcactatga
    18901 ccatgagtaa tcagcaacca atctgtcttt acttcttctg cagttaagtc tgtcaatgga
    18961 tttcctgtaa taaacgggtc aatcatcacg cgttggccat tttccatttc aattgttaaa
    19021 caggaatgtc catgatacgt aattttcata ttttacacct cgcgttttct ctgtatcttt
    19081 tttattaaaa acgatttcat cacttgcaca tcaatgaaaa aatatagctg ctaaatatat
    19141 tttcattgga ttgatagtac agtatgtaca aagcaattgt aacagataat acaggatgca
    19201 ccaagtacca agcagatata atctcaagtt tgaggtctct gctctgctta gcttctcttc
    19261 tcgtccctta actaattaaa tcagcgtaaa taggatggac gatcttttct aaatcggcta
    19321 cttttatccg aaggcttctc ccgatttcac cgcttgacac aattacttct tctttttctt
    19381 ttaaagaact gtctgctaaa aaacaataat caggatgtgc gagttttatt ccaatagggg
    19441 tgtttgctcc gtggggatat cctgtatgca ttaatacaaa atccattcca ggaaaaccaa
    19501 ctttacgatc tttcgtcact tgtctcgttt ttttgtaatc taagtgatcg ttcaaaggaa
    19561 tcaatgcgat gatcacccca gttttgtttc ctttcactac gagagtttta catatcaaag
    19621 ctggatcaat ccctcttttt tgtagttctt ctgtgaaaga ttcttctacc acatgactaa
    19681 aatcaagtgg ttgatagctg atcttttgtt cttctaaata acgttcgact tttgtttgac
    19741 tcatcattga ttcactccct ttattctatc gtttattata aagcgaggga tgctgtattc
    19801 aaaaattatt tgtttttcgc aaaaaaagag caagacgagc actctataga gaggttcatc
    19861 ttactctttt tgtttatttt ttatttcgac gttgagtagc ttccataatg actggcaaga
    19921 tcactgggcg gcgttttgtt tgttcaaata agtaacggcc taattgatct cggatgtctt
    19981 gctttaattt gctccactca aaatcattgc tttctaaatg tttctcaacg attgtttcaa
    20041 tcatattgct gctttctttc atcagatcac ggctagcttt tacgtaaacg aatccccgtg
    20101 aagtaatttg aggttttgaa atgattttct tttctcgccg actgatagtg acaaccgcta
    20161 cgaaaatccc gtcttctgac aagatttttc gatcacgtaa aacaatgttt ccgatatcac
    20221 ctatgcctaa tccatcaatc attacatttt ctgcacttgt agttcctgca acactcatac
    20281 gcttgttctt atattccagc acgtctccgc gtccagtaat atagatattt ttgtatggca
    20341 tccctactgc atgagccaaa tctgcatgag cagctaattc acgatactct ccttgaactg
    20401 gcacaaaata tgttggtttc atcaaattga tcattaattg caagtcatta ggattggcat
    20461 ggccagaaac gcgcatattc tcagagatca acttcactgt tccaccagct cgataaatga
    20521 tatcttccgt tttcgccacg atggtttcca tcgcgatgct tggcgtagta gtgatataaa
    20581 ccaaatctcc ttcttcaatc ttgacattac ggtgtgtacc gtttgccatt ttttgcagag
    20641 acttgatggg ttcacccatt cggccagttt ctaaaatgat cagttcttct ggatcatagt
    20701 ttttcatgtc tttcaacgta acaagcagat cttcacttgg taattgaagt ttttctaaac
    20761 gcatcgctgt gcgaataatt cgttcgaaat cttgaccagt caagacaact tttcgttgtg
    20821 ctttttctgc tgcatccaat acttgttgca ctcgttgcaa attacttgct acacaagcga
    20881 cgatgatacg cccttcccaa tatttgatcg tatcaaatac ttcatctgct atttgggctt
    20941 cagaagctac aggctgagga ttttctgcat ttgccgattc acttagtaag gctaagactc
    21001 cttctttgcc gatttccgcc aatcgtgcat aatctgtttg atacattggg atagccgttt
    21061 ggtcaaattt aaaatctccc gtataaacga tactaccttc ttttgttttc agattgatcc
    21121 ccactgaatc tggtatcgta tgagtggtac ggaaaaagct cactactgtt tcaccaaagt
    21181 ctatttctgt atgctcatct accacatgga aatccttaaa tcctttggct gcttcattac
    21241 gactgacatt caattttgct aactcgatcg tcaactctgt cccgaatact ggtacagaaa
    21301 tttttgacaa caagtaagga agtgccccga tcgcatctgc atgtccatgt gttaaaaaga
    21361 caccagctac acgatcaatg ttttcttcta aatacgtaaa atcagggatt acgacgtcga
    21421 tccccaacaa ctcattttca ggatatttta gcccacaatc taaaataaaa atatcctcgc
    21481 ccacttctgc gacatacatg ttttttccat tttcacgaac gccgcctaat gggataattt
    21541 taatggtact cacaaacttc acctcttctt atgacatcca agtttaaaga tgtcgatttt
    21601 cttctttatc taaatatatg agccattcca atgaagcata tgcaaaatca ctatttctca
    21661 acttatggag aatcagcagg aaaattacca gcacatccgc gttctgacag ttggatgggc
    21721 attttatttt ggatatactt cattaacaaa atggatcttt tgcgaaacgc tatagccaga
    21781 atacttatat aagtattcag ctgttcccca ttattataca acaaataaac taaatcgcta
    21841 gtatcagcaa ttgttagaac aactatgcac gtaaaaatcc ctctgtagca tctaggattt
    21901 cttttgctat tcctctttca tttcttcttc gtcggtttga aacatacttt tttcatttta
    21961 ccacattttt tgcaataact atagtgactt tttatatata cagaacctca tgttgatggt
    22021 gtgcaaacag cataagattt aagctagctt taagataggt tgtctattat caaatgcatc
    22081 tactaggagg gatgcaaaat atgaatttta tgaaacgtgc atggaaaagt acaaaagtaa
    22141 aatggggacg ttcattgtta ttgtttgccg tgttcacagc cattcttatt tttgtgctag
    22201 ctggcctcac gattcgaagc gctgcagaag aagcagcgaa tcaagcacaa aaagaagttg
    22261 gagcaacagt gactttaagt gccaatcgag aagcttcatt taaaaaacag gaacaaactt
    22321 cttcaagcgg ttctaccact gaagaacgtc cagatccagg cagtttttct cttacaccag
    22381 tttccttaac ggacgcggaa aaaatagctg aattagataa tgtaaagagt tattcctttg
    22441 aaagttccgc ctcagctatg gcaaaagatg gaataactgc catcactagt tctgattcaa
    22501 gtgaagacag ttcagaaact actgatgcag gcggtgaacc tgctggagga atgggcggga
    22561 atccgcaaat gactcaagca gactttcaaa tcagtggtgt gtcagcaact gcacaaaata
    22621 gtaatttttc tgatggaaca gcaaaaatca cggatggtga aggaatagat gacagcgaca
    22681 aaggcacaaa caatgtagtc attgattcta ctctagcaga aacaaatgac ctggcagtcg
    22741 gagatacttt cacaatcacg agtactgaag atgaagatac cacttatgaa atgacgatca
    22801 aaggaattta tgaatccagc gaaacaagcg gcagtatggg tatgaaattc aacttcatga
    22861 atccgtcgaa tacactttac acttcttaca cttttgcaaa tgaactaaat gggacatctg
    22921 acgataacac gatagattct gctatttaca ctctatctga tccagataaa atggatgagt
    22981 ttctcaaaga agctgagaag ctgatcgaca cagatacatt tagcttacaa tcaaatgatt
    23041 ccatgtatca gtcaatgttg gaacctttaa acaacgtggc aagtttttct aaaaatgttg
    23101 ttttactagt ggctgtagcc ggtattatca tacttactct gatcattatg attaccattc
    23161 gggagcgtcg gcatgagtta ggcgtcttgc tatctttagg agaatccaga agtaaaatca
    23221 ttctccaatt gtttaccgaa gtggctattt gtatgattct tgcattagga gttgcttcgc
    23281 ttagcggaaa cgtcgtcgcg aatgccgtgg gacagcagct acttgaccaa cagacagaaa
    23341 ccacgacaca aaaccagcaa gctcctggcg gtggacaaat gccaggtaac agacaagaac
    23401 aaggcggtca acgcgatggt caacaaggaa ccacgaataa tccatttgct gtttctgatc
    23461 aagtcagcga attggaaatc aatgtcaaac ctgcacaatt gggactatta gccggagtag
    23521 catttggaat cagtctgttt tctgtctttt tagcttctat agggatatta agattaaacc
    23581 caagaaaaat cctattaaac taaaggagga atttgatgtt acggacagaa caattgggat
    23641 tttggtatca agatccgcaa gatgcgcttt ataaagatgt agaactgaat ttcgaagctg
    23701 gaaaaatgta cgctatttta ggagcaagtg gttctggaaa aacgactttt ctttcgctta
    23761 tttctggact agatgcacca aaagaaggaa aggtatacta tcaagatcgt tcactgaaca
    23821 aaatcgggtt aagaagttat cgtaaaaatg atgtctcgat tattttccaa gcttacaact
    23881 tgcttcctta tttatcggct ctagacaacg tcatagcagc aatggaaatc actaagacca
    23941 agcaagagaa ttatcgacaa gttgctttag atcgactggc tcgtgtagga attgatgaaa
    24001 tattagcaaa aaaacaggtg accaaacttt cgggaggtca gcagcagcga gtcgctatcg
    24061 ttcgtgctat ctgctgtgaa catcaactaa tcgtagcgga tgagcctact ggaaatctag
    24121 atgaaacaac ttcacaagat atcgtcaaac ttttccaaga aatcgcccat gaacaaaatc
    24181 gctgtattat catcgtgact catgagattg aagtagcaaa aagctgtgat gaagtctttg
    24241 aactaaaaaa taaaaaattt caaaaaatcg aagtttaaaa aacaggataa tgatcaaata
    24301 aaaaatccga accatatctg tctcgcagat atggttcgga ttttttattt gcttgattca
    24361 attagtaata agtggttttt attttttttc gtcttttcga gaaaacttgt ctttgacttc
    24421 gtcgcctaaa tttcgagctt tttctttgat gtcagcacct agtgattgtg ctttcccttc
    24481 tgtttctttg ctcttgtcgt ctgttgcttt gccgtatgct tcttttcctt caccgactac
    24541 tttatctttc atatctttag aacgtccttt taaatctgcc attgtgcttc ctcctcttag
    24601 tttgtttatt gatctacctt cagggtaaca tcaacaacag atacagacaa acagaacgct
    24661 cgttttctaa aaaagatagt tagagctgtt gattaaaaac ttttttcgaa agtcccccat
    24721 actttgactt ctttttcttg gaccattatt tctcctttag cgataactgt atcaatatca
    24781 agcgtttctt tatccaagat acacagatct gcatcagcac caatttcgat ttttcctttt
    24841 ttatccaatt tcaatatacg tgctggatta ctggttatag ctcgtaaggc gatttccaaa
    24901 gggatacttt ctttttgcac agcttctttg atccctacta gcaatgcctt ggcacttcct
    24961 actcctaacc ctaggaaatg attgttttca tcaaaataag gcaagcttcc ttgtccatct
    25021 gaggtcatcg tgaaattatc taaagaaaca tcttcctcga tcaatcgttt cagtgctttg
    25081 ctgaagcgaa cttcaccatc tgtcttctcc caaaaatcag gatcttcgct agcagtgaag
    25141 tcaatcgtgc caccacgttt ggcaaatgcc acgcaagctt caaataattc tggtgtgcga
    25201 tttgcatgag taggcaaaaa ttgtgtgatc ggaatttctg tttcttctac gattcgtgtc
    25261 aatagctcta gctttctttt tcctccgcct aagtggacat tgatgatccc agcttttccg
    25321 gataacatgc ctcctacacg agcatctgct actgcacgag cgaactcttc aaaacttggc
    25381 tgagaagaac ggtgatcgga tactgcgatt tctccgattc cgataatttt atcaattgtc
    25441 aaaaagtctt tgatgataga atctgttact gtttttaccg gcaatcggta cgaaccttcg
    25501 tatacataag tggagattcc ttctgcttcc agacctttcg ctttgctgat caacgcagtc
    25561 atatctctac cttctccgtc tgttcccaaa caaccgacaa ctgtcgttac accagctgta
    25621 gtcaattggc tcaatgtgac ttctggcgtt cgattttgat aaccgccttc tcctcctcca
    25681 cctaaaatat ggaaatgaca gtcaatgaaa cccggggtta gtacttttcc ctcacctgaa
    25741 agttcttcta cttccactcc ttcgtagccg ccttctagct gttcttctac agccaaaatc
    25801 ttcccaccgg caatcagtac atccattttt cctaagtaat ctggtgcaaa cacttcaatt
    25861 tgtcgaatga ttttcataca tttttcctct ttctttaagt ataactgatg ataggatctt
    25921 aaaaaataat ccaaacgata ggatctttac tcctttgatt ttaccgtaaa atgacggttc
    25981 ttggagtcct tatctactgt ttggattact tttttattta caggtctcca gtactactgc
    26041 agacctattg caatggcaat catgatgaaa atagttccta aaacaaacag gaatccttgc
    26101 atcttgattt ggaatcttgc ccattttgcc cattcgatcc gtgcaacacc tagcacacca
    26161 atcaagctgg ctgatacggg tgtaaaagcg tccataaaac ctgaaccaag ctgataagca
    26221 agaactgcta cttgtctgga tacacctact aaatctgcca gtggagccat gattggcata
    26281 gtcaaagctg cttgtcctga atttgatgta acaaccaagt tgaacaaact ttggaagatg
    26341 tacatcgccc aagcaccaat gacagctgga acaccggtca acgccgtccc gatcccatgc
    26401 aaaatcgtat tcaaagctga aggaacagat gcatcagatc ctcccaagac aagaagaatc
    26461 cctttggcca tacctactac gattgctgta ccagctaaat cagctgcacc agattggaaa
    26521 gaagaagcga tgtcattgac tttcattcca tctaatttga aaagaacagc aatgattcca
    26581 gcaactaatc ccatcacaaa gaattgagaa gcgatttctg gaatgtaata gcctttttga
    26641 gtcacgcccc aaacgatcca gacaaggaca actaacatct ctaataagat caatttatgc
    26701 ccaagcatga attttttatt ttcatcagat gtctttttga tatgagaacg gaaataatca
    26761 tctgatttgt aagtcaacga actttctggt tttttacgga ttttttctgc atatatcatc
    26821 atataaccag cggctaatgc agtaacaact acccacataa tcaatcggaa tgtcgcacca
    26881 gacaacacgg ggattccagc aatcccttga gccaccgcta cgctaaacgg gctcatccaa
    26941 gaggtcgcat ttccgacttg agatgcgaca taagtcacgg ttactgctac gatcgagtca
    27001 tatcctaacg caatgacaaa tggaaccatc accattgaga atggaattac ctcttctgcc
    27061 atcccgaatg tagcgccacc gaatgaaaaa gcaaagaata atagcggtaa agctaaacgc
    27121 tccagtccct tagttttact gataaacgca tagatacctg cgtcgatcgc tccggtacgc
    27181 ataataatac caaaagcacc tccaacaaca aggatcaatg cagcgatccc tacagcagat
    27241 ccatacttat ctccagatac tagtccttca aaaacaaaat ttaagaaacc aaagccgcca
    27301 aaatcatctg ttccccatat tttggctgtt ttatgcaatt ttttagaagt atcatagata
    27361 ttttcgccgt actgatcgta aagcacatca tctgtcaagg agatttcatc tagtttttcc
    27421 tgcgtaagat ttttttctcc gtcagcaatg actttttcca atcctttttc cggaacatcc
    27481 agtttttcac gttctgctgg atgatcttgc agttcttcta attgatcaaa cacatacgac
    27541 ttatccagct cgtaagcata acggaaggaa tcttgacgta aaacagtacg agtacttgtt
    27601 tcgccatttg catctttgta ttcaatatct tgcgtgctga actttcctgc tggaacgaca
    27661 aaagtcagta tccatgcaaa gatgactaca ccaaaaataa tgacatacgt atggggtgtc
    27721 gataatttag tgaagtcgcg tttcggtttt cctgaagaat ttgttttctt caaatttatt
    27781 tcttcctttc ttttttcagt aattttgatg aa
//
LOCUS       DAFLVO010000036        27094 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.036, whole genome shotgun sequence.
ACCESSION   DAFLVO010000036 DAFLVO010000000
VERSION     DAFLVO010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27094
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.036"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..1245
                     /locus_tag="L1U99_001587"
     CDS             <1..1245
                     /locus_tag="L1U99_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1212132.1"
                     /translation="NLTDIKNLRRIYFQRSKIARLLTEIVDSKVTIEKFAENHFLSIS
                     RAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFGVYFGVFNGFSMPFRESVMNE
                     AKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGNQPIGKRFFSDEYFKSSEGMK
                     IIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELDGAFGLAEAHFHDIHMISQKM
                     SVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNWIFDFEMTSFTSKKQLQFFFE
                     TYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFLLVGICPVSYFEAPIHVCIDF
                     SQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSDCLLEKFNKEQIIWKNPPTPD
                     DWEYFGNTIIREKNRHLTEKIS"
     gene            1522..3582
                     /locus_tag="L1U99_001588"
     CDS             1522..3582
                     /locus_tag="L1U99_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HBN1212133.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            3665..4234
                     /locus_tag="L1U99_001589"
     CDS             3665..4234
                     /locus_tag="L1U99_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1212134.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKSDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(4409..5215)
                     /locus_tag="L1U99_001590"
     CDS             complement(4409..5215)
                     /locus_tag="L1U99_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212135.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            5353..6867
                     /locus_tag="L1U99_001591"
     CDS             5353..6867
                     /locus_tag="L1U99_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HBN1212136.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(7270..8253)
                     /locus_tag="L1U99_001592"
     CDS             complement(7270..8253)
                     /locus_tag="L1U99_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HBN1212137.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(8258..8905)
                     /locus_tag="L1U99_001593"
     CDS             complement(8258..8905)
                     /locus_tag="L1U99_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1212138.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(8990..9622)
                     /locus_tag="L1U99_001594"
     CDS             complement(8990..9622)
                     /locus_tag="L1U99_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBN1212139.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(9638..10189)
                     /gene="coaC"
                     /locus_tag="L1U99_001595"
     CDS             complement(9638..10189)
                     /gene="coaC"
                     /locus_tag="L1U99_001595"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HBN1212140.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(10186..10923)
                     /locus_tag="L1U99_001596"
     CDS             complement(10186..10923)
                     /locus_tag="L1U99_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HBN1212141.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(10920..11909)
                     /locus_tag="L1U99_001597"
     CDS             complement(10920..11909)
                     /locus_tag="L1U99_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBN1212142.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            12167..12709
                     /locus_tag="L1U99_001598"
     CDS             12167..12709
                     /locus_tag="L1U99_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1212143.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            12726..13811
                     /locus_tag="L1U99_001599"
     CDS             12726..13811
                     /locus_tag="L1U99_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1212144.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            13823..14629
                     /locus_tag="L1U99_001600"
     CDS             13823..14629
                     /locus_tag="L1U99_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1212145.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            14630..15457
                     /locus_tag="L1U99_001601"
     CDS             14630..15457
                     /locus_tag="L1U99_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1212146.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            15454..16527
                     /locus_tag="L1U99_001602"
     CDS             15454..16527
                     /locus_tag="L1U99_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1212147.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            16955..19651
                     /locus_tag="L1U99_001603"
     CDS             16955..19651
                     /locus_tag="L1U99_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1212148.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            19728..20216
                     /locus_tag="L1U99_001604"
     CDS             19728..20216
                     /locus_tag="L1U99_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1212149.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            20228..20722
                     /locus_tag="L1U99_001605"
     CDS             20228..20722
                     /locus_tag="L1U99_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1212150.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            20743..21552
                     /locus_tag="L1U99_001606"
     CDS             20743..21552
                     /locus_tag="L1U99_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1212151.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            21549..22370
                     /locus_tag="L1U99_001607"
     CDS             21549..22370
                     /locus_tag="L1U99_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1212152.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            22421..24520
                     /locus_tag="L1U99_001608"
     CDS             22421..24520
                     /locus_tag="L1U99_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HBN1212153.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            24517..25635
                     /locus_tag="L1U99_001609"
     CDS             24517..25635
                     /locus_tag="L1U99_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBN1212154.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            25674..26552
                     /locus_tag="L1U99_001610"
     CDS             25674..26552
                     /locus_tag="L1U99_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1212155.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            26743..26895
                     /locus_tag="L1U99_001611"
     CDS             26743..26895
                     /locus_tag="L1U99_001611"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBN1212156.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
BASE COUNT         8623 a         4666 c         5669 g         8136 t
ORIGIN      
        1 aatttgacgg atatcaaaaa tttaagaaga atctactttc aacgatcaaa aattgctcga
       61 ctgttaacgg agatcgtgga ttcaaaagta acgatcgaaa aatttgcaga gaatcatttt
      121 ttaagcatat caagagccta tgtaaaaaga agagaattag tctcttttct tgaacagcat
      181 caaataaagt taaagaaaaa catattagtt ggggaagaaa taaacatacg gaacgtatta
      241 tttggggtat atttcggggt ctttaatggt ttttctatgc catttagaga aagcgtcatg
      301 aatgaagcaa agagtatcgt gcaatatttt gaatatctgt tcaatttaaa actgtctgca
      361 acaaaacgaa tcaaattcaa tttgctaacc actattagtt tgttgagggc ctatgggaat
      421 caaccaatcg gaaaacgttt cttttcagat gaatacttta agagctcaga aggaatgaag
      481 atcatcaagg atttatcaca tatttctttt cttcatatcc ctaaagagca gatcattgat
      541 gagatttctt atatcatgtt gtttttgatc acggaagaag aatttgaatt agatggcgca
      601 tttggacttg cggaagctca ttttcatgat atccacatga ttagtcaaaa aatgtcagtg
      661 gaattgattg atcaattacc attttcgatt gaaatctctg aagaagaaag actatatata
      721 cgaaaagaac ttcgtatggg tatgatgcat gtcaatcgaa aaaattggat attcgacttt
      781 gagatgacta gctttacgtc taaaaagcag ctacagtttt tcttcgagac gtatccaata
      841 ttcagtacag caatccaaaa ggtcatacaa gagaataaac gctatttctt gggaaaagat
      901 gaacgtttca tgattcgctt attttatgat tatctctttt tattggtcgg tatttgtccg
      961 gtatcatatt ttgaagcacc gattcatgtc tgtattgatt tttcgcaagg atctgcttat
     1021 accgattaca ttatttctca agtgaaagga tttaaaaatt acaatattgt gattgagagt
     1081 cgaatcactt ctcgtacgaa tatttattta tctgattgtt tacttgaaaa atttaataaa
     1141 gaacagataa tttggaaaaa tccaccgact ccagatgact gggaatattt tggaaatacc
     1201 atcatcagag aaaaaaatag acatttaact gaaaaaatca gctagtattt atggatggca
     1261 gctttgtctc acatatttat tagctgattt atgttttttt caaagaaaag gtaactagat
     1321 ataactagat ataactagat atattactta acaaaattaa aaagtacata agttattatt
     1381 ccgattttct tgaaacaata aaaaatcaaa aaaaatactc tcctaatagt ccatcttctt
     1441 ttgattttat ttatataatg aaatcatctt atgaaaatta ctacttcatg tttagacaag
     1501 agtagggagg actaagaata aatgtgttca aaaagacgtt caaaacaact aaataaacac
     1561 gcttgtcgtt tagataagga acggtcgtgt tctgaaaaac actacgttaa gtttatgatg
     1621 cgcacgatgc tgatcagttt atctgtaggt gtctatatgc atgtacccgt tcaggcaacg
     1681 acacaaacca tcaaggtcgt acgtacctct gtttctgaga ccactgattc ccctatcact
     1741 attactcata ctttcactga tgcaaatgga aaacagctac ttcctgcatt gacttcctat
     1801 aataaagtca gttatcctcc aacgataaac cactactggt taattcctaa caaaacatta
     1861 tggacatcgg aaaccggaag cagtgtgccg ctttctatct tttccgatat gactgatcct
     1921 acaaaaggtg atcagttaaa acagatcact gatattttga atcatgcttt gacagatata
     1981 aaggacggtg gaagcgcaca agtttcttat gtatatgaaa aagattattc acagtttgaa
     2041 agaaagaaaa tcgatgttct ggcagggaca aaagtttcga tatctgatct ggtagaaagg
     2101 ctgaagaacg cagatggaac acaaggagat atgtccaaag taatttcaaa caatgggaat
     2161 atcgtggata cgactaatac aggaacatct actatttcct tgtcctattt tgatccaatt
     2221 gctttaaaaa caatgactgc atctgctgtg atccatgttc gtgctgatca aacagctatc
     2281 aaaggaaaag atcttcactt aagaacagga gagagttacg cccctaaaga tcttgttgaa
     2341 tatgtaacaa aaagcgatgg aacttcagga aataaagaag aaatcaaaat gaacgggaca
     2401 gtagatacta caactccggg agaatatccc gttgtattaa cttatataga ctcgaaaaca
     2461 tcaaatgtgg cagaaacaac agctgtagtt tatgtagaag catctgctgc ttcatcgact
     2521 gtcatcactc attttataga tagtcaaaca aataaagaac ttcaagcaga aacacatatg
     2581 agtagtgtaa atcgtattcc tgatttgcgc ctacctgctg aattttctga tcgagtgcca
     2641 aatatagatt tatcgactta tgaacaaaat gggaaagtca cttctatttc tgattggatg
     2701 caagcaaacg gattagacag aaaaagtcac tggtcggaga tccttgaagt acttcactca
     2761 gaactgatga ataataggaa gcaatcagga ggggaaatta cctttactta tgtttatata
     2821 ccagacaatc gttcattaga aggtcatgat cttattgttc atccaaacga aaaaataaac
     2881 aaagaagagt tgatccaatc agcaacaaat tccttaggta aacccgtacc gttaaaggat
     2941 gtatcggtta caatcaatga agtaccattg gaggatggtt atttgaccaa acaaacaggt
     3001 gattttacga ttatgtatag ttatcatgac ccgtattcac tccaagaact ccatgctcag
     3061 tcactattac atgttttacc attaaacaaa cagatagatc aaaaagaaca aaaaagacaa
     3121 gaagaaagct tgtcagaaaa aaaacaacaa atggctcatg cagtttctcc aacagggaaa
     3181 gtaaaacaaa caagaagcct agagttagca agaatatcta gaaaaatctc agaatctaat
     3241 aaaacgataa ggcaagaagc tcatttggcc ccacaagttt ctggattgga aaatgaaatt
     3301 ttagagccta aaataaaaca acaatcagaa aaagaatttg ttgctaaaca gtcggaagat
     3361 cagaaggaat cagatgacca gaaggaaacg aagaaaaaac gcttgtcaac tattgattcc
     3421 accgatgagc atctgcagcc gcaagtacca cttcctagtc cgggaacacc cgcacctggt
     3481 ggaggtattc cttcttctgc tttaggagat ttcatgcgag gtatggcagg aacatgggta
     3541 tacgctaatc gaaatgaatt tgacgcagat gactggttct gatttatatc tctatctgtt
     3601 atagtcaaat aagtagctga gtcatatgtt atttggcata atggagacga ggagggatag
     3661 aaaaatgtta gataaaacgt taccttacgc agaaatctgg atgacaagac cacttcaaca
     3721 aaatgttcca atcacgcctt tagcggaagg ttttgaattt cgattttatc aaaaagaaga
     3781 tgaatctgct tgggcggaga ttgagacttc cgttggggaa tttcaaacga cagatgaagc
     3841 acttgagtat tttcaacaaa actttgctcc ttatcctgaa gaacttgaaa gaaggatgtt
     3901 ttttgtagag acaaaaaaag gagaaaaagt agcaacctgt accgcttggc gaaaaaaatc
     3961 aagagagcaa gtgtatccgg tttttcattg gttagcagtg aaatcagatt accaaggaaa
     4021 agggctcgca aaagcattga ctgccagagt cttgcaagaa tttcctaccc tccatacgga
     4081 cggaccaatc tatcttcaca cacagacatg gagccatcag gcgattgctc tttataaaaa
     4141 aatgggtttt acttttattg ctgaaaatct agacggcaca cctaatccag attatgaaaa
     4201 agttatgcag gttttaagta aattagataa ataacgaaat ggtgaaataa gtcctcagta
     4261 ttgggataaa aaacgaaata gtcattcctc atatcttact tttttgagtt aatactatcg
     4321 gataactaat ggcatgccat acattcaaaa aagaaggggc agtgacaaaa gtattgtcac
     4381 tgccccttct cttgtttttt agcatgtttt atcgtttgat ttttttagga ataaaattct
     4441 tgatgaacgt aaatttttgg taatcgtttc gactatagag gtaaccaaat acactgaaaa
     4501 caactgctcc aataaaatta acaaataaat ccttcatagt atccatgatt cccacgtcta
     4561 agtaaccatt ttggatgatt gttttatctg ttttaccatc tgcattttga ctttcaatga
     4621 ttgtccgagt gatatctgga acatgataga cagtgtttcc gtctttactt aactccacac
     4681 tattgatttg ctggatgatc gtatcttttt gcatatcgaa ttgcagtaat ttatctgctg
     4741 aaaattccac aaactcccac ataacaccaa ctgtcatcga aaaacagaag gaaacaactg
     4801 ctagtaataa aggagtcaag ttcatggttt ttgtattttt attgagcaaa taaacaaggg
     4861 aaaagccgac acccccagct aaaaatccgc tgaatgcatg tagaaaagta tcccacattg
     4921 aaaaatagcc ataaaaatca cttaactctc ctaaaactgt tgaactaaaa ataaaagata
     4981 acaaaatgat ttctagcata tttggaatct gtatctttaa tatcttttcc agaaaataag
     5041 ggatttcaaa taaaattaat gtcagtaata aaagcattgt atttccccag tgttggttcc
     5101 agacctgatc cactagcata ataacgacga tgatacgtaa taaaatatag attccgtttg
     5161 tgattctacc tgcagttttt gtactgttcg taaaaaaggt tttcaaatga ttcataaaat
     5221 aactccttca tgtatatcct taattatact aagaagcgtg tgtttaccaa agctatatga
     5281 cttaaagaaa aacagagttg atattgtgaa aaaaatcact taatatagta taaggagaaa
     5341 agggggatac aaatgaaaaa attagttgct ggtttattaa cagccgttgc acttcttgct
     5401 atgagcgcat gcggcgcaga tcagaaaaat acagcgcaga caagttctag tacgaaggaa
     5461 tctgccgaag tatcatcagg cgcttctgaa caagtatata cagatccaaa agaaatgaaa
     5521 gaatcttatg atgtcgtgat tattggagct ggtggtgcag ggatggcagc agctatcgaa
     5581 gcaaaagatg ctgggttgaa tccagtaatt ttggaaaaga tgcctgttgc cggaggaaac
     5641 acatctaaat catcaagcgg tatgaatgct tcagaaacaa aatttcaaaa agaagaagga
     5701 atcaaagact cgaatgatgc cttctatgaa gaaacgctaa aaggtggtgg aggaacgaat
     5761 gataaagaaa tgcttcgata ctttgtcgat cactctgctg atgcggtcga ttggctagat
     5821 caaaacggta tcaaactgga caacttaacg atcactggag ggatgagtga aaagaggaca
     5881 catcgtccgt ctgatggctc ggctattggt ggatacttag tggaggggtt attgaataac
     5941 gtccatgagc gggaaatccc tatttttgtc aacgcagatg tgacagacat taagaaaaat
     6001 ggggaaacgg tcaatgaagt gactgtacat gttcaaggag aagaaccaaa agaggtcacc
     6061 ggaaaagcaa tcgtagttac cacaggcggt tttggtgcca gcaaagaatt tattgaaaaa
     6121 tatcgtcccg atttagctga ttatattacg acaaatcaag aaggatcaac tggagatggt
     6181 atcaccatga ttgaaaaatt aggtggacaa accgttgata tggataaaat acaaattcat
     6241 ccaactgtgc agcaggatga gggggtcttg attggtgagg ttgttcgcgg agaaggagca
     6301 atcttggtcg atcaagaggg gaaaagattt gtcaatgaaa tggatacaag ggataaagta
     6361 tctgcagcaa ttacagcatt gcctgaaaaa tcagcttatt tgatttttga ccaaggcgtg
     6421 cgtgatcgtg ccacagctat tgaattttat gaccaaaaag gatatgtcac aactggaaag
     6481 acaatggaag aattagcaga aaaaatcgat ttaccaaaag aaacactagc aaaaacagtt
     6541 gatggatgga atacggatgt tgcggagaaa aaagatgctc aattcaaccg tgccacagcc
     6601 atggaacatg acttatcgtc tccgaattat tatgcgatca aaatcgcacc aggaatccat
     6661 tacacgatgg gcggtgtgaa aatcaatacg aacactgaag tattagataa agaaaaccag
     6721 ccaattaggg ggttatatgc tgctggtgaa gtcacaggtg gcttacatgg aaacaaccgg
     6781 atcggtggaa attcagttgc ggagatcatt atttttgggc gacaagcggg catacaagca
     6841 gctcgatttg cttcggaaaa tgaatgaaat agaacgtaaa taaaaagagg ttgtgaaatc
     6901 agcgttttga gctaataccg agggtcagct gattgaacac tgtttagtga agaggttgtg
     6961 aaaaagctgc cctgcatcaa gtaataagaa cagccaagta aaaacagctt cttatgtttt
     7021 taacttggtt ggacttatta ccgcagatgc aagcttttga acaccgttta ttcggaaaaa
     7081 gagcgtggga caaaagtaaa gaacactttt gtctcacgct ctaaacacgt ataaacggcg
     7141 gaagcagaag aaattccttc ggaaataagc tgaaattcac aaaaatttga aaagcaattt
     7201 tcgtgaattt cttcttattt cttggagtta aacgcttctg tcccagcctc ttttttgatc
     7261 agcatgattt tattcagtta tcttcaaaat gatttttccg atgtttttgt ttgcttccat
     7321 atattcatgc gcttgtttga ctgcgctgaa ttggaatgta cggtcaatga ttggccgaat
     7381 cttgccattt tctagaaaag gcccagcttt ttgcataaaa gtttgtgcga gctctgcttt
     7441 atactgatca cttctaggtg tcaataatgt accaagcagt tggacacgtt tcccaatcaa
     7501 tacaccaagg tctatctcag gcacgatggt cccacctagc ataccaatca agacccaacg
     7561 tccatcaacg gctatagaag ctaaattctt ttcccagtaa gaagcgccga tgaaatccaa
     7621 aataacatcg actccccgac cttcagtgat ttttcgtacc tcttcttgaa agtcttgttt
     7681 tttatagttg atcaattcat ctgcaccaag ttctttacaa aaggcgagtt tttcttctga
     7741 tcctgcagta acgatgattt tcgcgtgaga aagctgtcta gctaattgga tcgctgctgt
     7801 tcccacacca cttgctcctg catggatcaa gacagtttcg ccttcttgta attttccaag
     7861 ccagtaaagt gtttgataag cagtcaaaaa aacttctgag attccagcag cagaaacata
     7921 gtctagcgta tcagggagaa ggattgcacg atcggcaggc atcacagcat attcggcata
     7981 accacctaga ttgactaatc cgtatacttt tgtcccagga gtaaaagtgg agatatcact
     8041 tttattctca actacctctc cagctacttc gactcccaaa atagggtagg gaggtttcaa
     8101 agagactgat tctcttttca taatatctgt tcgattgaca gctgctgtat ggactttgat
     8161 cagtaattcg ccttgttttg gtttaggaac aggcacttca atttgttcta atacatctac
     8221 agaaccagga tgcttgattg aaatggcacg catggatcta ttcctccttt gcccattctt
     8281 ggaatgctgt attcaactct ttgctacctt cagaaagtac tagagtcgta cgagaaatat
     8341 ccgtttcttc cactagagcg gcaagtacag cagcaactgt agagcgagtg atcgtttttg
     8401 atgccttctc attaggctta gttaattgaa tggaagtaac ttcttcatcg ttagtcaatg
     8461 tgactggttg aagaatgaca aaatctaagt tagttcgttt cagccattca tctgcataat
     8521 gtttagtaat ataataatct gtcatggact caggccattt tgctggttca tctgcataaa
     8581 cagcactgac catcagatag cgagagacat gcgcattttc agctgcgatc actgttttga
     8641 ttgcgccatc caagtctact tgcagaagat tctttccttg agagccggca gcaaaaatca
     8701 atacatcgat gcctttgaat gcttcggtca ttttttccac ggaccaagtt aaatcaaaag
     8761 agacatacga aacattctct ttttttacta atgtttggga agcaacatct ctcacccctg
     8821 caaaaatttc atgggaactt ggagctaaat cttttatcag gtgtcggcca atttgtccgt
     8881 ttgcacctac aacaaaaatt ttcatttgga tcatcctttc gacgtcaaat ctttccattc
     8941 aatagtaaca ccaaaagaga aaaaaatcag agatcggcta cgatgactat cagttagtaa
     9001 gagaagggtg cttgaagtat cttaacaaga cattgcatac tgctgcagtc gcaagacctg
     9061 cgacgattcc ttcaggtata ccacttgtaa aaataaccgc tagaatagct gaataaacag
     9121 catttaaatt tgttccgatg actttggcat aatcttgctg gaataaaaag tagatcatat
     9181 tcatcactaa aatcgtattg gtcaatgaac cggaaagtcc agctaagaat aaagaaacgg
     9241 aatctgcttt ttgtttcatt agtttgcgca gacctttata aacgaaataa ggaaccaccc
     9301 caatcaagat gcgaggaata aacgcgatca gcaaggcttt ccagcttcca tgttctgttc
     9361 cgatgactgg gataaacgga gaaaagacaa aagacaaagg tgtttggata actgtgctac
     9421 ggatcatgct gatcagtcca aatgtaccgc caagaaaagc acctagtctt ggtcctaaaa
     9481 cgatcgaagc aatgattaca ggaatatgca tggttgttgc attgattgga ccgataggga
     9541 taaaacctaa aggcgtaaca gctaataaaa tcaaaatagc taaaaacatc gcagttaatg
     9601 taaagttttt tgtatttttc ataagtactc cttttttcta agcatttctt tcattaagag
     9661 tcagcatgac ctgttcgatg atcgtctgaa tatcagctaa ggcacctttt ccaaaatctc
     9721 cacaagctaa aagagattct cttggttcaa tttcctgata gccgacagat ctcaatgttt
     9781 ccagattacg ctgagtgatc gggttttgat acatattcgt gttcatggca ggggcaatca
     9841 attttggtgt tcccactgga agcgccattg cgactgttga aagaagatcg tctgcaatgc
     9901 cgtttgctag cttgccgata atgtttgctg tagcaggcgc gatgagaaac aagtcagctt
     9961 gttttgctag ttcgatatga ttgattacct gcggatttga ttcttgcatg acgtctgtat
    10021 ggactgcgcg cttcgacaga gattgcaagg ttaatggcgt gataaaatgt gtgctgcttt
    10081 tagacataat cacatctacc tgggcaccta atttgacgaa ttgacttgta agatcagcgc
    10141 ttttgtaagc agaaatactt ccagtaacgc ctagtaagat ctttttcatt ttgattcctc
    10201 cagtctaatt ttctcagtaa tcaatgcagc aatctcagat ttactttgag cttcttccac
    10261 tgttccatct ttagataaga gatagccgtg gtgtgtctcg ccatggattt ccgtcaaatc
    10321 atttgcgaaa ataaaatcag ttttgttatt tatcagacta ttttttgcga ctgccagaag
    10381 agattccttt ggtacatcta ctaatagttt gaaaccaatg atttttgctt ttggctgcca
    10441 ttcacgtaga taagaaatga tttttggtgt tttcttcaaa acgagcacaa gatgctcggt
    10501 gttagaagag atctttgaaa cagtggtatc tgtctgttca ttttccgcaa accaattgtc
    10561 cagttcttct tgcgttgaag aagtgggtag gttttttgcc agctgttctt ctgaaaaact
    10621 aaaagcagga gtaaaatcac tgactgccat actgtggata atcgcatcgt agtgttcttt
    10681 tttcgttagt tcttctaatt gtaaaaataa gtccagtgca gattcgatcg tataaatcgt
    10741 tatattggag tgtcttttcg gtttcagtgc ttgtttcgta gtcacgtaat cgattgtggt
    10801 atccggattg gcagctaaat aatcagctaa tgcttgccct aatcgtcctg tcgaatgatt
    10861 tgtaatagca cgtacttgat cgattttttc agtcgttcct ccagctgtga ttagaatctt
    10921 catttatggt cacctacatt tactagtgtt cttccttggt gtgttccagc aagtagttta
    10981 gatgctgttt caggcaattg atccagagta atctcttgga cgaccagttc atctgcaatc
    11041 tgcaaatccg ccatctgttg ccataaagaa agacgttgat ctattggtac attgacagaa
    11101 tcaattccaa tcaactggat gtttcgcaga ataaaaggca agacagtcgc gtttagtttg
    11161 attcccccag cattgccaca taaagctact gcaccgttat aagagatcaa tggaagaaga
    11221 ctgcttagct gctcgccacc tactgtgtcg atgacatagt cgatttgctg ttttcctaaa
    11281 gcttttgttg tctctggcag aaattcatca ggtcgtacga cttgcaaagc acctagactt
    11341 tttagccatg tgacagactc ttcttttctg gaaaaggcaa tgattgactg gaatcctagt
    11401 ttatgtaaca gggctatcgc tgtactgcct acaccgccag aagcaccagt aacgacaact
    11461 tttttatcgg aggtcatacc ttgacggatt aaagcgttca cacacaacat agcagtaaac
    11521 cctgctgtac caaggatcat cgcttgacgc agcgtcatat tttttggtag aggaactaac
    11581 cagtctcctg gtactttttg atattggcta taaccgcctg gatgggtgac gccaagccca
    11641 aaaccagtag caagtacaag atcttctttt gaaaaacgtg gattgttact ttggacgaca
    11701 gttccggata aatcaatccc tggagtcatc ggatatgttc gtatcacctg accagactcg
    11761 ctcattgcca atgcatcttt ataattgaca tcagaatagg caatttttac caagacttca
    11821 ttttcagcca actcagtaaa tggcagatca ctgattgctg tatggaaaac aggttccttt
    11881 attacctgaa aagatcgaaa agcgttcatt cgtgagacac tccttttaaa attttctttt
    11941 atcataccat aaagcctact cttttattct tgttcttccg taaatttaga caaaaattag
    12001 gtgaaaaata aagaatcaaa caactagaat ttattccaaa agataaagaa atattcagca
    12061 aaaaaaattt tacaaagggt tgcctttttc aataaatttc gtatactaat acgagtggta
    12121 gtaaacagga agtttactat tagaaaactt cgattcggag gaaattatgg aaattggtga
    12181 gaagttaaga aatttgcgca tccaaaagaa tttgacacaa gaagaactag gcgaacgcac
    12241 agatttgtca aaagggtata tttcccagtt ggaacgagat ttaagttcac catcaatgga
    12301 aacattcttt tctattcttg aagtcttagg tgtgactcca gaagaatttt ttcatcaaga
    12361 agcagcgaat ctgcaagtgg tttattcaaa agaagatcat acggtttatt tcgatgaaga
    12421 aaacgggtat gaattggaat ggctcgtggc tgattcgaat gaaaaagaaa tggagcctgt
    12481 cttgctgact tttgaaggtg caggagaata taagacgttt gaaccttcat tatctgaaac
    12541 gtttattttt gtattagaag gggaattaga gttaagctta ggagagacgg tctatgtggc
    12601 aaaagcagga cagtcgatct attatcaagc gacaaaacaa catcaattaa ggaatcatct
    12661 caaaaaacga acaaaagtat tgattgttgc aacgcaatca tatttgtaat atagggggta
    12721 aaaacgtggg gaaaccaatc atttcatttg atcaagtagt gaaacgctat gatgatgaaa
    12781 cagtattaaa aaaagtaagt tttgagatcg aacaaggaaa attttataca ctgcttggtc
    12841 cttccggctg tggtaaaaca acgatcctac gtattatagc tggattcacc gaagctacag
    12901 aaggggacat ctattttgaa gggaaacggt tgaatgattt gccagctaat aagcgacaag
    12961 taaatacagt cttccaagat tatgcacttt ttcctcatat gaatgttttt gataacgttg
    13021 cttttggatt gaagatcaag aaaatgtcca aatcagatat cgaaaagaag gtaaaagatg
    13081 ctttgcgtat ggtccagctt cctggatacg aaaaacggga gattagtgaa atgtctggtg
    13141 gtcaaagaca gcgtgtagcg attgcacgag caattgtaaa tgaaccgaaa gtattgctat
    13201 tagatgaacc gttatcggcg cttgatttga aactacgtac agatatgcag tatgaactgc
    13261 gggatctgca acaacgatta ggaatcacgt ttatttttgt tactcatgac caagaagaag
    13321 cgttggcaat gagtgatgag atttttgtca tgaataaagg gaaaatcgtc caaagtggta
    13381 cacccgtaga tatttatgat gagccaatca atcatttcgt tgctgatttt gttggggaga
    13441 gcaatatcgt ggacggtgta atgatcgaag ataatctagt tgagtttgtt ggtaagcaat
    13501 ttgaatgtgt cgatggcggg atgcgtctaa atgaaccagt tgaagttgtt ttacgcccag
    13561 aggatttgac gatcacgaca ccagataaag gaaaactagt cgtaacggtc gatactcagc
    13621 tgtttcgtgg tgtccattat gaaatcatct gttatgatga acagcaaaat gaatggatgg
    13681 tccattcaac gaaaaaagct aaagaaggaa gcaaagtagg attggccttt gagccagaag
    13741 atatccatgt catgcgtttc aacgagtctg aagaagaatt cgatgcacgt cttgacagct
    13801 acgaagaata ggggggacaa gaatgaaaac aatgcgcagg atctattccg tcccttatat
    13861 tttgtggctc ggtttattcg tgatcgcgcc tgtattaatg atcatttatc aatctttttt
    13921 tgatatgaat gggcaattca cgctgaataa ttatctatct tattttacgt cggggacatc
    13981 gctttctatg acgatcaatt ctgtatggta tgcatttttg atcacgtttt tcacgctgat
    14041 catcagttac ccgactgctt attttttaac aaaactgaag cacaagcaat tatggctgat
    14101 gctgattatt ttgcctacat gggtgaatct gctgcttaaa gcttacgcat ttattgggat
    14161 tttcagtgtg cacggcagcg tgaatcattt ctttgatttt atcgggatcg ggccgaaaca
    14221 gatattattc acagacttca gttttctgtt cgtggcaacg tatatcgaga ttccatttat
    14281 gattatgcca attttcaatg cattggaaga gatgaatcct tctttgatca gtgctagtag
    14341 agatttaggc gcgaatagct ttgagacctt ccgacgagtg atttttccgt tatcattaaa
    14401 tggtgtgaaa agtggtgtcc aagcagtatt tattccttct ctttctttat tcatgctgac
    14461 tcgtctgatt ggcggaaatc gggtgatcac tttaggaacg gctatcgaac agcatttctt
    14521 ggttacacaa aactggggga tgggttctac aatcggtgtg attttaatca ttgctatgtt
    14581 catcgtgatg ctcctgacag gcgagaagaa aaaaggaggt cgctcataaa tgaaaaaatt
    14641 taaatggtcg tatctttatt tagggatcgt ctttttattc ctatatgcac cgatcttcta
    14701 tctgattttt tattccttca atgaaggagg aacgatgaac agctttacag gatttacttg
    14761 ggaaaattat gaagctgttt ttgaagatac acgtttgatc attatcgtat tgaatacgtt
    14821 catgctggct ttcttatctg cattgatcgc cacgatcatc gggacatttg gggctatggg
    14881 aatctattac acgaaaaaac gacgtgcacg gacagcgttg ttgagcatga ataacatctt
    14941 attagtctct cctgatgtta ttatcggtgc tagtttcttg attttcttta cactactagg
    15001 attcggatta ggttttcaga gtgtattgct ttcccatatt gctttcagca ttccaatcgt
    15061 cgtcttgatg gtcttgccaa aattgcagga aatgaacgat tcaatggtcg atgcggctag
    15121 agaccttggt gctaataatt tccaagtagt caaaaatatc attttgcctt atctttctcc
    15181 aggaatcata gctggatatt ttatggcatt tacctattct cttgatgatt ttgcggttac
    15241 atttttcgtc acaggaaatg gctttacgac gctctcagta gagatctatt ctcgtgcaag
    15301 acaaggaatc agtttagaaa tcaatgcgct aagtgcgtta gttttcttgt tctccatgat
    15361 attggtcatt ggatactact ttattagtaa agaaaaccgt ccaaaacggc tgaagaaaaa
    15421 cagaagagta cgcgaggggg tggcacggct gcgatgaaaa aattacaatc tctgttttta
    15481 ggtattctca tcattattgc ggtgctgctg cttggtgttc gtcaacttga aaaaacaagt
    15541 ggcatgagtg gagcaaaggt acttaccatc tataactggg gagattatat cgatcctagt
    15601 ttgatcacga aatttgaaaa agaatatgga tacaaagtga attatgaaac atttgattct
    15661 aatgaagcga tgttcacaaa aatccagcaa ggtgggacaa actacgacat cgctatacca
    15721 agtgaatata tgatccaaaa aatgatcaaa gaaaaactag tacttccatt agatcattcg
    15781 aagatcaaag gattaaataa tattgatcca cgatttttag acttggattt tgatccagat
    15841 aatcagtatt cgattccata tttttgggga actttaggga tcgtatataa cgataaattc
    15901 tttgatgcaa atcaaattaa gcattgggat gatttgtgga agccggaatt aaaagacagt
    15961 ttgatgctga ttgacggtgc acgagaagtt atggggcttt ctttgaatag tttaggctat
    16021 tctttgaata gtaagaatat ggcacagctg acagaagcag caaataaatt gaatcattta
    16081 acaccaaatg tcaaagcaat cgtggcagat gagatcaaaa tgtatatgat caatgaagaa
    16141 gcctccgtgg cagtgacatt ttctggcgaa gctgccgata tgatgtggga aaatgaacat
    16201 ttacattatg tgatcccacc agaaggatcc aatctttggt ttgataatat cgttatgcca
    16261 aaaaccgtga aaaataaaga aggtgcctat gatttcatca actttatgct agaaccggaa
    16321 aatgcggcac aaaatgcaga gtatattggt tattctacac caaatgaaga agcaaaagcg
    16381 ttattgccaa aagacatttc gtcggacgaa caattctatc catctgatga cacgatctcc
    16441 catcttgaag tctacaaaga tctaggatcg aaatacctag gcatctataa tgacctattc
    16501 ttagaattca agatgtatag gagataatgg caaaactcag taagaatggg gacttatcaa
    16561 cgttctaaag agctaaaaat cgtccttttt ctatctgagt tttccaatct tctaccaaaa
    16621 gcggatgaaa cgccgctttt tttgtgttat tttatttttt ctaccacgtt tttctaccag
    16681 agaaaagtgg acaaaaccat tgtaaaatag ggcccgagac gggctagtaa atctaagatt
    16741 gaaaaagtta cagaaggata aagtaattgg aaactatgca aatatactta acccttctgt
    16801 aatctattaa taaaactaat atatgaatcc agttcaatat ttgtagctat gaaaaaacat
    16861 aaaaatcata ttagataaaa actaaattgg tagataaatt attttgtcag atatctgagg
    16921 caaatattcg actatttgtg tttcaaagta aaaattggaa tacaaatata gaatagacat
    16981 attgcagccg atagtttatt atgcttttag acacattaaa ctggaggaaa aaatgaaaaa
    17041 gagcgctaaa gatcgagttt ttgatgagct gatacgacta acagggaata tgtcttctgt
    17101 cactgccgag aaaatttcga agaatctagg tatctctcgt cagaatgcca gccattattt
    17161 gacgagatta gtggaagata aaaaggtcga gaaattaccg ggaaagcctg ttttgtggaa
    17221 gcctttagat gaatatgcgg ttgtagataa tacggagcaa ataaacgaag cctttcattc
    17281 tgtagttggt catgacggaa gtctgagaga ggtcattcaa aaatgtatag ccgctgtcaa
    17341 atatccgcct aacggactca gtgtattaat aaatggagcc acgggtgttg gaaaaagttt
    17401 tttagccaca aaaatttttg aatacgctat ccatgagcaa attattgaaa aagatgcacc
    17461 atttgctatc ttaaactgtg ccgattatgc ggacaatccc gaactgcttt cggcaacact
    17521 gtttggatac aagaaggggg cctttacggg ggctgaaaag gataccgatg gtttattggc
    17581 aacggccaac aacggctatc tttttctcga tgaggtccat cgcctatcga aagaaaatca
    17641 agaaaagctc tttctattta ttgatactgg aaactatcgt ccagtcggtg aaaatgtaaa
    17701 ttggcattct gctaaggttc gttttatttt cgccacgacg gaaaaaggtg aaaattattt
    17761 attagacacc tttgatcggc gtattcaaat tagtgttatg ttgccaactt ttgaagatcg
    17821 ccccattcga gaacgattag agctgattca attatttttt caaaatgaag cggatgtttt
    17881 acaaaaagat attattgttt caagagaagc cttgtcttta atgttatctc atccctttag
    17941 tgggaatatt ggtaagctga agaatatcat taaaatcagt tgtgcggatg tgtatagtcg
    18001 aacacaagaa gaaccattaa cgattgggaa aaatgagatc ttgattcagt taaatatgct
    18061 ggaatccgaa gtagaaagct tgccgattgc tagtttattg ataaagaaaa atcaaaagat
    18121 aaaaacggat cgaatcaaac cgtttgatta tgattcgatt ttggaaaaaa ttactcagct
    18181 gataaatgaa ggtaatttca atgaaaattt ttcttcgata aagaatgaag tacagcattt
    18241 ggtgcatcac attgataagg attctttttt atcaatgagt agaaaattga tgattcagat
    18301 gtttagaaag gtctgggtat ccgttttagg aaaaacgtac ggattgacga cgagtggacc
    18361 tgttgcagaa attattagca gatcctatgt catttcccca agctataaga cagacttaac
    18421 cgggataaat cgtacattag ctgcaaatct acctcggacg acttacttat gtaatcagtt
    18481 cttggagcat ttaccaccgc tctcagaaaa ggacgagaac tttctaagac tgcttattgt
    18541 cgtgacttta tctgattatg tagatgaatc catcgagctg aagggcctgt tgcttgctca
    18601 cggagatagt acggctagca gcattcaagc agtagtgaat caattatgcg gcaattatgt
    18661 ttttgaagcg ttggatatgc cagtagagag taatgtgtca gagattgtcg aatcgacaag
    18721 gaatttcgtg aaacggcaag tgaatacaga tagtctagtg ctgatcgtag atatgggctc
    18781 tttaaatcaa atttacacac agatcaagaa cgatttaaaa ggggagttac ttcttctgaa
    18841 taatttgacg acttccattg cacttgatat tggcttgaag atgacgatga atgcgccatt
    18901 taaacagatt gcggaggatg cagcagacaa gtattcaatc aatgttcaat actttgaagg
    18961 cttttctcaa agtagcaaca ttatcatttc ctgtatgtcg ggtttgggga tttcggacaa
    19021 attgaaagat gtttttcgtc atcatttatc ggatgaatcc atcgaagttt tcacgaagga
    19081 ctacagagaa ctacgtgaat taatcgacca aaatgatgaa acttattttg acaagacaaa
    19141 attggtcatc acgacttcgg atcttccacg ttccttttca attcctaata ttaatgttta
    19201 tgacatctta gacggtgatg gagcagccaa tttggagcat attttgagtc ctgaaatgaa
    19261 gccggcagaa tttaaccgct tgattcagga gctagtaaaa ttcttttcgt tggaaggaat
    19321 tgcggaccgt ttgaactttc tgaacccaac gatcgtgatg agtgaagtgg aaacagtcat
    19381 ttctaaatat gaaaattact atcatttcac tttaaatggc cgtgtaaaac taaatctcta
    19441 tatgcatacg gcattgatga tggaacgttt attcttggct cggacagaaa aatctgaaga
    19501 accgaattat gatttgaaac cagatgaaga tgaattttat tatgtttcta gaagtatttt
    19561 tcaatcaatg gagatgaaat ataattttaa agtcaatgct tatgagcttt cgctgctcta
    19621 tgaattatta ggaccgtata ttcaaaaata aagtgtctaa aaaagtgtct aatctgtttt
    19681 ttttaggtta gacacttttt ttaatgtgaa ttaacgtgat taaaccaatg tttttaaaag
    19741 ttggcacagg aattgcttat ataaaagtga acagaaagaa aggaattaac catatgaaga
    19801 aaattctaat agcgactcac ggtcacttag cttcaggctt tcttagcagt attcaattac
    19861 tgacggggaa ggttcaagag attacggtga ttaatgctta tgtggatgag tgtgattttg
    19921 aacaggagtt gaatgtattt gtaaaccagg tgaacgagca ggatcagatt tttgttttta
    19981 ccgatttatt tggcggaagt gtcaatcaga agattaccaa aacctttttg gagaaagaga
    20041 ttgctgtaac tattttgtct ggctttaatc tgccaattct gctcgaaata gtattggcaa
    20101 ccaaggaatt aacaaaggag gatattcagg aactggtaaa taaatgccaa caggaattaa
    20161 agatgaccat tcttgatgag gtacatgtag taaatgaaga ggaagatttt ttttaggagg
    20221 aagaaaaatg attaaagcag tgcgaattga tgaacgatta attcatggac aagtagcgat
    20281 gacttggaca aagagtctaa atttaaccgg gttagtagta gcaagcgatg aggcggctac
    20341 caacgatatt caaaagatga cattgaagat ggctgcacca tcgaatgtca aagtcattat
    20401 taaaacagtt gatgacgcga ttcatttgtt aaaagatccg cgggcgaagg acatgcgctt
    20461 gatggtttta gtccctaatg tcaaagatgc ggtaaaagtt gcgaaagctt tcccaacgga
    20521 aatcgaatta atgaacgtgg ggaatgctgg gaaaatgaca ccgccatcgg aagataagaa
    20581 aaccttatca aaggaagtga tgttaacgac gtcagaaatt caagacttaa aagaattagt
    20641 tgaactttat ccagataccg tttttcagcc tacaccggcg atggaaaaac gttcagctat
    20701 ctctattttg agtgattttt agaaaaagga aggagaaaaa ttatgtatga tgcatttgta
    20761 gtcgctttgg ccgtttttat tggagttgct ggacatgaaa tgttcgggat gtccatgctg
    20821 agtcgtccga ttgttgttgc tccgttagca ggagcgttga tgggggattt gcagacgggg
    20881 ttgattgtcg gggcgtcact agaagccatc tttatgggtg tcgtcaatat cggaatctct
    20941 agtacggcgg agccttcttt ggctgctggg ctggctacag cgttcgcaat caaaatggga
    21001 ggaaacgtgg atgcgattat tcccattgtc tttccactag cagtattagg attacagtta
    21061 atgaatatga ttttttcttt tgtatgtgga ccgatggctg ctaaattttt caaatttgca
    21121 aaatctggtg atcaaaaagg aatcatcaat ctgcacttct ttatgtggtt tgtccactat
    21181 gcgctttatg ctcttattcc attctttgcc gttttatttg gagcagatgt tgtcaaaagc
    21241 gtcttggata atattccaga ggtcatcatg aacggattaa cagtcgctgg aaatctgctg
    21301 ccggcagttg ggatggcgat gctgttacgg atgctttgga gtaaaaatat tgctgtgtgg
    21361 tttttctttg gggccgttgt tatggcgtat ctcgagttac cattgattgc aattgccgca
    21421 gttggaacga ttattgcaat tgttatagcc caaagagatc tacaactaaa aaatatatct
    21481 gttcatgcag ttcaaagcga tgctgctgta aatgcaacgc ttgaccaaga agaggaggat
    21541 ttctttcaat gaaattagct gatggaattt ctaaagatga gaaaaaattg gttcggaaga
    21601 tgttttggcg ctcgatgact atgtatgctt cggtgaatcc ggtgacgatg ggcggcggtg
    21661 gtttcgccta ttctatgatg cccttcatta atcatttcta caaaagtgaa gaagatcgag
    21721 ctgcggcgct ggaacgtcat acacagtatt tttcgacgac cattccttgc gcgtcctttg
    21781 tcatggggat tgcggcatcg atggagaagg aaaattctga aaaagctggt tttgacgtgg
    21841 aaagtatcaa cgcgatcaaa acgagtttga tgggaccatt ggctggaatt ggcgattcat
    21901 tgttctgggg agtttggcgt gtcgttaccg cgggactagc gatcaactta gccaatgccg
    21961 gaaatatttt ggcaccaatt atctttttag ttatgttcaa tatacctaat tacttgatgc
    22021 gatactatgg cggcgtttta ggctattcat taggctctaa atatattgaa aagctgtatg
    22081 cgaacgggtt aattgaaatt ctgacaaaag ctgctagtat cttgggtctg atcatggtag
    22141 gtgcaatgac gatcagtatg gtcaaattca ataccgtttt gagcttttca atgaagggcg
    22201 aagaactaat gaatgtccaa gaaatcctcg atagtatttt taaaggaatt gtaccgttat
    22261 tggtaacatt gagctgtttc aaattactag ataaaaaagt cggcgtcatc aaaattattt
    22321 ttggaatggt cgtcttggga attttattgt cattacttgg aatcgcatag taggaagctg
    22381 cagctactag gctgcagttt ttttagcaag gagggaaaag atgactatta atgaagtaat
    22441 ttattcaccc aaacacccat tttttaatgc tgagttaaac gacggaaatg tgactacttc
    22501 aaacgaatac agctactatc ggaatattcc tgatgtaaag ggattgacct tcgatgtaag
    22561 taatcaaaag acattagcaa accttgatgt ttgcgggacg attcaaacgt tgacctttta
    22621 tcgagaaaat ttactaactg aggaaaaacc aggtgtttgg gtcaataaac agctctctca
    22681 aaccaattcg ttatccttaa aggttgaagt aaacgggatt gtctaccatt tgtcagaatc
    22741 ggatcatcgt attgaagtcg atgtgattca agactgtttg cctagatata ttcatcatta
    22801 ttcgacgttt aaggtcattg tagtatcctt tgctcccata ctggctaata agcgtttaag
    22861 tatgcttgtt caacaggttt acattgtgaa tgaaacacac gaaagccttc aagtttcagt
    22921 gaaagatgtg ccttcgtatc aagagaagta ttcggatcag caaaatgtgt tgatttctca
    22981 aaaaggaaat aaggacacga tcgcacaaca ggaagtggca agcttcgcca ttgcttttgt
    23041 ggacccaaat gcttttgaag aagtaatgac ttttcaggaa tctgatatcg aaaaatggct
    23101 gaaggaaaca ttgaactatt ttgctcagct atttgggcag ctgtcaatgc caaacgatag
    23161 agttgtccat ctctatcgtc gtgcacttta tcaaagcttt tctagtttcg gtatgaatcg
    23221 acagggacag gtcgtcggca gcaattgggg cagctatcct gctactaatc gaatttggaa
    23281 taaggatatg tattacgcat cattgccatt caccatgttt gaaccggagt tatgtcaaaa
    23341 aacggttcta tggtttgatc aatatggcgt taagtttcct ggttcaaaat ttacaggagg
    23401 tatcaatcat tctctgagta attcgttatc cagtgcgtta ctggctagtc tttattttga
    23461 acatactggg gatacaaaat tctttgagcg gtgtccgcag gttctactga atgcttcaag
    23521 aattattgag gacatattag ctcaacgtcg gtcaggggaa ccaatgcttt ttccatctgt
    23581 ttggttatca gacgcctttg cacttggaaa gtatcatacc ggcagcaatc tttgtctttg
    23641 gaaggcctgt attggacttg cagaaatttt tgaagcccta gaacaactga gtcttagcaa
    23701 gcgatacaaa aacattgcct gtaaactaaa ggaatcaatt tgtaaacaaa tgactatcga
    23761 tggtcctttt ggtgagcaat ttttggaggg aatcggtgat gaggagaaaa caacctattc
    23821 agtgaagcac tatcaaaaac cgattcttga gcaagggtta atctttttaa gtgatgtgat
    23881 tgtggatgga aaaattaatt tattgatgca tgatggagaa gaatcagaca ctacgttgat
    23941 gcctttttat caatttttag ataataaaga tcatttatat cagaacacca tggccttttc
    24001 tgctagttct ttcaatccaa cctatagcga ggaaatcaaa ggcatcactt ggggattaga
    24061 atccggcgcc acttttcctg gctttatcac tgttttaatg agcgagctgc acaaccctca
    24121 agctttcgta acccgattag aagaactaat ttgtttggca gatttagacg gttcgtggtg
    24181 gtggtggccg tatcgcttag aggctcaaca aggagaagtc gtgcgagact ttggctgcgg
    24241 caaatgcggc tgggcatcgg gtctttttgt cagcctaatg atcagtcaat atttcggatt
    24301 gaaattcaaa aaaggagtat tgcaaattga tcctgttgat aatttaacgt tttcttggaa
    24361 gaatttgaag ttcggtcaag ccttcatttc gattgaatgt acgcaatccg agttgagtat
    24421 ttcaaatttg tcagaaaagc cattgaaaat aagtgatacg aaaaaaattc ttcacgtaga
    24481 aaagggaaaa acgattcaca ttcaaaggag aaaaagatga gtatactaaa aaatattacc
    24541 caatttaaaa aaatccagag tcgagcaatc actcccgaaa atccaacagg cgagaaaggt
    24601 aaagctgcga tgttgccaag cgagctagga ccaagccgca aaggtcgtgg cgcaattccg
    24661 ctgacttctg gtgaagaaac tgtgattgcg gatattactg gaacgggaat aattcgtcat
    24721 atgtggatga cgattcgtga tcgaacagaa tttggcagtt ttgttttacg tgatttaatc
    24781 ttaagaattt attgggatgg gtcggatagc cctgctgttg aaagtccttt aggggatttc
    24841 ttttgtaatg ggtttggaga gcgttgcgag gtgaactcgt tgccgatagt ggttaatcct
    24901 acagggggct ttaattccta tttcgaaatg cctttccaaa catccgctaa aattacgatc
    24961 gagaatttac atccgaagga tatgtcctca tttttttata cgataaatta cgctttggtg
    25021 gacgaattgg aagaaaatag cctatatttt cacgcaaatt ggcatcggga acgcattacc
    25081 aaattacagg aggattataa gttaattgat cgattaaagg gtcaaggcta ttacgtgggt
    25141 acttaccttg cgcttacctg cctagaacgt tattggtggg gcgaaggcga gtttaaattc
    25201 tacattgatg gggatagtga gtatccgacc gtaacctcaa caggttcaga agattatttt
    25261 ggcggggcgt gggcctttca tgagtacgat gagttcggac gtccacatgc gaaaaactat
    25321 tcaacagcct ttttagggta tccttaccaa tcaaatagag atgccacaag agatcgtttt
    25381 gaaacgggaa aattgaatgc cgttcatgcc tttggtgacg acgcaatgcc acgacatggt
    25441 ctttatcgtt ggcatcttca agaccccatc tgttttaccg aagatttatc ggtcacttta
    25501 caacaaatcg gcaacgatga tgttcgctta tttgagcggc aagacgatgt tgctagtgtc
    25561 gcttactggt attcaacaga agcttcagga aatactaaac gtcatttcac tgatcgagaa
    25621 cgcttgccgc gttaatgaag tgtttttcac atattcgaag ggaggaacct atgatgatat
    25681 atggggcaat tgaagctgga gggactaaat ttgtctgtgc agtcggtact gaggaattaa
    25741 cgattttgga aagagtcagt tttcccacaa caactccagt tgaaacaatg aagcaggtca
    25801 ttgatttttt taaacctttt aaggaacaat tggcaggcat cggggtcggc tgctttggtc
    25861 caattgatat tcaatgcaaa tcaacgagtt tcggtcatat cacatcaaca ccaaaacttg
    25921 cttggcaaaa tttcaatttt gtaggaacgc taaagcaata tttcaatatt ccgattgaat
    25981 ggacaacaga tgtcaatgcg gcttgctatg gtgaatatgt tgctggttct ggcaaagggt
    26041 tagcaggtgt tgcatacttc actgtgggaa caggtatcgg aggtggtgcc ttgttcaatg
    26101 ggactttcgt ggaagggttc agtcatccgg aaatggggca tatgttgatc aagcgacatc
    26161 caaaggacaa tttttcagga aactgtccct tccaccaaga ttgtttagag gggatggcag
    26221 caggaccagc gattgaaaaa cggttgggtg taaaaggcca gaatttattg gctgacgatt
    26281 cgttttggca gattgaagcc ttttaccttg cccaatgtgc atacaataca acactgatgt
    26341 tttcgccaga tagaattatt tttggcggtg gtgtaatgaa acaagaacac atgaagaaaa
    26401 aagttcagga taaatttgtt gagcttataa atggatatgt tgaaatacca ccaattgata
    26461 gctacattat tacgcccgaa ttaggtgata atgccggaat aatcggcgga ttagcattgg
    26521 ccagaaaagc ggtaagaaat aagcaaccat aattaatgaa tgtttcattg atactcatgt
    26581 caaaagtatt taaccgagta atcaaatgat caaatgaagt tggataaagc gaaaatgaat
    26641 tcaaataaaa aggctctaag tcaaatcgtg ttgttttcat taaatcactg aaaggaaatg
    26701 cttctgcgtt tccttttttc tttttgttgt gcgctgtata ccttgaggat attcactggt
    26761 ggcgtacact taaatagtaa tatattgtgt tactttatgt ctgtggtaat agttatagtt
    26821 gcttaccaat gtatgttcat ttttcgaaat gttgacttca taatccttgg cttaatgttt
    26881 gaattttttt ggtgatagat tttttcagcc gtataaaata aatcgtaatt ctattataga
    26941 gagttgtgat tataaaaaga tagcaagaaa aaaaaagaaa gtttctatac attttaaata
    27001 ttttattcct atttctattg ctaaaaaagt agaaattcta tatttacctt taactctcgc
    27061 ttctcttgca aatgtagtta gcattttaat cgat
//
LOCUS       DAFLVO010000037        25706 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.037, whole genome shotgun sequence.
ACCESSION   DAFLVO010000037 DAFLVO010000000
VERSION     DAFLVO010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.037"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(132..509)
                     /locus_tag="L1U99_001612"
     CDS             complement(132..509)
                     /locus_tag="L1U99_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212157.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            765..1493
                     /locus_tag="L1U99_001613"
     CDS             765..1493
                     /locus_tag="L1U99_001613"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBN1212158.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1493..1747
                     /gene="purS"
                     /locus_tag="L1U99_001614"
     CDS             1493..1747
                     /gene="purS"
                     /locus_tag="L1U99_001614"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HBN1212159.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1749..2420
                     /gene="purQ"
                     /locus_tag="L1U99_001615"
     CDS             1749..2420
                     /gene="purQ"
                     /locus_tag="L1U99_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HBN1212160.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2421..4643
                     /gene="purL"
                     /locus_tag="L1U99_001616"
     CDS             2421..4643
                     /gene="purL"
                     /locus_tag="L1U99_001616"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HBN1212161.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4628..6067
                     /locus_tag="L1U99_001617"
     CDS             4628..6067
                     /locus_tag="L1U99_001617"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBN1212162.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6090..7142
                     /locus_tag="L1U99_001618"
     CDS             6090..7142
                     /locus_tag="L1U99_001618"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBN1212163.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            7139..7717
                     /gene="purN"
                     /locus_tag="L1U99_001619"
     CDS             7139..7717
                     /gene="purN"
                     /locus_tag="L1U99_001619"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBN1212164.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7714..9249
                     /gene="purH"
                     /locus_tag="L1U99_001620"
     CDS             7714..9249
                     /gene="purH"
                     /locus_tag="L1U99_001620"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBN1212165.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9265..10539
                     /gene="purD"
                     /locus_tag="L1U99_001621"
     CDS             9265..10539
                     /gene="purD"
                     /locus_tag="L1U99_001621"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBN1212166.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10661..11575
                     /locus_tag="L1U99_001622"
     CDS             10661..11575
                     /locus_tag="L1U99_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBN1212167.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11708..13273)
                     /locus_tag="L1U99_001623"
     CDS             complement(11708..13273)
                     /locus_tag="L1U99_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBN1212168.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13266..14717)
                     /locus_tag="L1U99_001624"
     CDS             complement(13266..14717)
                     /locus_tag="L1U99_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBN1212169.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14731..15747)
                     /locus_tag="L1U99_001625"
     CDS             complement(14731..15747)
                     /locus_tag="L1U99_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1212170.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15967..17055
                     /locus_tag="L1U99_001626"
     CDS             15967..17055
                     /locus_tag="L1U99_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HBN1212171.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17109..18635
                     /locus_tag="L1U99_001627"
     CDS             17109..18635
                     /locus_tag="L1U99_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBN1212172.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18637..19842
                     /locus_tag="L1U99_001628"
     CDS             18637..19842
                     /locus_tag="L1U99_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1212173.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20099..21076
                     /gene="guaC"
                     /locus_tag="L1U99_001629"
     CDS             20099..21076
                     /gene="guaC"
                     /locus_tag="L1U99_001629"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HBN1212174.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            21340..22764
                     /locus_tag="L1U99_001630"
     CDS             21340..22764
                     /locus_tag="L1U99_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBN1212175.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            23225..24334
                     /gene="pdhA"
                     /locus_tag="L1U99_001631"
     CDS             23225..24334
                     /gene="pdhA"
                     /locus_tag="L1U99_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HBN1212176.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            24337..25314
                     /locus_tag="L1U99_001632"
     CDS             24337..25314
                     /locus_tag="L1U99_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBN1212177.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            25339..25587
                     /locus_tag="L1U99_001633"
                     /pseudo
     CDS             25339..25587
                     /locus_tag="L1U99_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863426.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
BASE COUNT         8322 a         4383 c         5783 g         7218 t
ORIGIN      
        1 caaaaaagaa gcagatccgt tagcggttct gcttctttta gtttattata ttttcttatc
       61 aataatagga acctgatttt aaaagcggct acctctttac cgtgcctctt tacatacaaa
      121 aaatagagga attaagcgta aatggcttgg ctattataac taaaatgctg gttatggaga
      181 tgttgcagca agttttcgag aaaagcgtat tccatctctt gtccattgaa taagatctgg
      241 atacgataat gatttttgaa acgcttctgt tcatgaatct gactgattga aagttcgcct
      301 ttgtgttctg tctgataaag aaaagtcctt ttacggcatt cagcacagcg cttggttgct
      361 cggcggattt ttcggaatgt ataaaaacta gtatctttat tgcataaata aacgtctttg
      421 atcgacagca aatcattata tagacaggaa cgttcttcag ctgttaattc tgataaaaaa
      481 agctgacctt gttttattgc atcttccatc ggcaagtgcc tcctcgaacc cattatccaa
      541 atttttagtt aattctaata taccatcatt aagtataaat gtaaacgctt gttgatggta
      601 taagattttc gtttctgata aaacacgaac attaaaagaa tctaatgcct taaatgtaca
      661 tatttttgtt gatttataaa aagatgattg ctaaaattta aagtgaaaaa acgaacaaaa
      721 aacgatgtat ttgcttttaa tgtaaataaa aaggagagac gtacatggag aagaaagaac
      781 ttttgtatga aggaaaagcc aaaaaaatat atcttacttc tgatgagaac ttgatttgga
      841 tagaatattt agatcaagca actgcgttga atggcgcgag gaaagaccag ataagtggaa
      901 aaggagaatt gaataatcaa atcacaagtg caattttccg ttatctgact caaagaggaa
      961 taaaaaatca ttttattgaa caattgtcta aaaccgaaca attagcaaaa aaagtacaaa
     1021 ttatccctct ggaagtggtt atccgaaata ttgcagcagg aagtttctca aaacgtctag
     1081 gtgttcccga aggtaaagaa ttcatcaaac caatcattga attctactat aaggatgacc
     1141 agttggatga tccatttatc aatgaagagc atatctattt cttacaactt gcaaagccgg
     1201 aagaaatcag tgagctgaaa gcccaagcgt tggctattaa tgaaattttg accgaattat
     1261 ttgctaaggt cggtttggtt ttagtagatt tcaagctaga atttggccgg tcgaatggac
     1321 aaattttgct tgcggatgaa gtaacaccgg atacttgccg attatgggat gaacgtacga
     1381 atgaacatat ggacaaagac gtttaccgca gagatctagg tgatttgatc ccagtctatc
     1441 aagaagtata taaccgtcta tcggaactaa ctgaagaaaa ggagcgagta tgatgtattt
     1501 cgtaaaagta tatgtaacct ataaagattc agtgttagat cctcaagggg aggcagtaaa
     1561 aaaagcagtc catcgtatgg gatatgaaac aatcgaagat atccgaatag gaaaatactt
     1621 tgagatacaa cttgctgatg cagaagaacc aatcgataca gtgattgaaa cgatttgtga
     1681 caagctgctt gcaaatgtaa atatggaaac ataccgatat gaaatcaaaa aaatggagga
     1741 agtataacat gaaatttgcg gtcatcgttt ttccaggttc aaattgtgac gcagatatgt
     1801 tatgggcagt tcgcgagatc atgggcgctg atgccgaatt tgtacggcat gatgagtcct
     1861 ctttagaagg atttgatggg gttttactgc cgggaggatt ctcctatggt gactatttga
     1921 gatgcggtgc gattgctcgg ttttctacaa tcatggaaga agtgattcgt tttgctgaag
     1981 aagggaaacc agtattcggt acatgcaatg gattccagat attgacagaa gcaggacttt
     2041 tgccaggtgt actgagacga aatgagtctt tgcattttat ttgcaaaact gtaccattga
     2101 aagtcaaccc caagacggcc tttacttcag agtatgaagc cgacgaaata atctatcttc
     2161 cagttgctca tggggaagga aattatttct gtgacgaaga aacacttcaa gaactaaaaa
     2221 aaaataatca gattgccttt acttataatg acaacatcaa cggcagcgtg gaaaacattg
     2281 cagggattac gaacaaagca gggaatgtgt taggaatgat gcctcatcca gaacgtgcag
     2341 tagaagactt gctaggatca gaagatggga aacggttctt tgcttccatt ttaaaaaact
     2401 tcggaaaggt gaccgtatag atgaaaacat tgaaagaacc gacagctgaa gagatcaaga
     2461 aaaaaagaat ctatgccgaa tggggattga ctgatgaaga atatcgaatg atcgaagaag
     2521 atatcttagg aagaatgcct aattatacgg aaactggact gttttctgtt atgtggagcg
     2581 aacattgttc ctataaaaat tctaaaccgg ttctacgcaa atttcctact agtggacctc
     2641 atgtgttgca aggccctgga gaaggcgcag gcatcgtcga catcggtgat ggactagcag
     2701 ttgtcttcaa agcagaaagt cacaatcatc cttcagccgt ggagccttat gaaggagctg
     2761 cgacaggagt tggcggaatc atcagagata ttttcagcat gggggctcgt ccaattgcgt
     2821 tgctagattc attgaggttc ggcgaattag ataatccaag aacgaaatat ttactagaag
     2881 aagtagttgc aggtatcggc ggatacggca attgtatcgg cataccgact gtaggcggcg
     2941 aaattgcatt tgatccttgt tatgaaggaa acccattagt caatgcaatg tgcgtaggtt
     3001 tgattgaaca caaacatatc cagaaagggc aagccgctgg cgtcggtaat tcgatcatgt
     3061 atgtaggtgc aaaaacaggt cgcgacggta tccacggagc aacttttgcc tcagaagaat
     3121 ttaatcaaga agaagaacag caacgttctg ctgtacaagt aggcgatcct tttatggaaa
     3181 agctgctgct tgaagcgtgt ttggaattaa tcttgcatca ttcggattct ctaataggta
     3241 tacaggatat gggagcagca ggacttgttt catctagtgc ggaaatggct tcaaaagctg
     3301 gctcaggact tatattgaca ttagatgaag tcccacaaag agaaactggg atgacacctt
     3361 atgaaatgat gttatcggaa tcacaagaac ggatgttgat ttgtgttaaa tcaggagagg
     3421 aagaaaaaat ccaagaacta tttcagaagt atgatctaga tgcagtcact atcggtaaag
     3481 taacagacga cgggcaatat cggctatatc atcaaggaga agaagtagca aatctgccag
     3541 tcgatgcatt agctgaagat gcaccagttt atcataaaga aatgaaagaa ccagctcgaa
     3601 tcgtagaatt tcagcagtta gctccttatc agccagttat cgaagaacct ggacaagtat
     3661 tgcttgatct gctgcagcaa ccgacgattg cttcaaaacg ttcaatctac gaaacttatg
     3721 attcacaagt acaaaccaat acagttgtcc gtccaggaag cgatgctgct gtgatgaggg
     3781 ttagagggac gaataaagcg ttagctatga ccacagactg caacgcgcgc tatctgtatt
     3841 tggatccaaa aatcggagga caaatagcag tggcagaagc tgctagaaat attattgcta
     3901 gcggtggtaa gcccttggcg atcaccgact gcctgaacta tggttctcct gataaaccag
     3961 aagttttttg ggaattatcg acttcagctg acggaattgc tgctgcgtgt gaaacgttag
     4021 gaactcctgt tatttcagga aatgtctctt tatataatga aacggatggt caagcaatct
     4081 atccaacacc aatgattggt atggtcggat tgattgagga tcataaacat atcactactc
     4141 aggaattcaa aaaatcaggg gatctaatct atatattagg taagacgttt gcagattttg
     4201 atggcagtga attacaaaag atgcagcttg gaagaatcga aggtgtgatc cgaaactttg
     4261 atctatccat tgaaaagaga aaccaagagt tagtattgac agccatccaa aacggattga
     4321 ttgaaagtgc tcatgactgt tcagaaggtg gcttggcaat tgcactggca gaatcagctt
     4381 tcaaacatca gctagggata tctgtacagt ttgaattgtc ctctgctcaa ttatttgcag
     4441 aaactcaatc aagatttgtg ttgacagtcg caccggaaaa taagacacga ttcgaagaaa
     4501 tgatgggaga tgctgctgtt ttagcaggta aggtgacgga tgaagcgata atcgaaattt
     4561 cagcaactga cggtcagatc aaaatagaaa ctgcagtagc aagaaagtgc tgggaggatg
     4621 caatcgtatg tcttatgaag tgaagagttt aaatgaagaa tgcgggatct tcggtgtttg
     4681 gggtcatcca gacgccgcta gtgtggcata cttcgggctc catagtcttc agcatcgagg
     4741 acaagaaggt gcaggtatcg tgtccaatga tcgaggaaag cttaaggggc atcgagattt
     4801 ggggctgctt tctgaggtat tcaaagatca aagaaaattg cagcagttaa caggagaagc
     4861 tgcaatcgga catgtacgtt atgcaacagc aggcaatgga agtgtggaca atattcagcc
     4921 ttttctattc aaatttcatg atcagtcgat cggcttagcg cataatggta acttgatcaa
     4981 tgctcgttcc cttagaaaag agttagagga aaatggggcg atcttccatt ctaactccga
     5041 tacggagata ttgatgcatt tgatccgacg aagtgaagaa acagattttt taaataaatt
     5101 aaaaagtgct ttgaatgaag tcaaaggtgg ctttgcctat ttattaatga cagaaacggc
     5161 aatgattgcc gctttggacc caaatggttt tcgtccatta gcaatcggac aaatgaaaaa
     5221 cggagcatac gtgattgcct cggaaacttg tgcattagaa gttattgggg cacgttttat
     5281 aagagatgtc cagcctggtg agatagtgat catcaatgac gaaggaatcc agattgattg
     5341 ctttacgaag gacacgcagc tttctatttg ttcgatggaa tatatctatt ttgccagacc
     5401 agattcaaac atcgcaggga tcaatgtgca tactgcacgg aaaaatatgg gacggaattt
     5461 agcgaaagaa tcgccagtaa aagcagatat ggtcgttggc gtacctaatt cttctttgtc
     5521 agccgcaagc ggttatgcgg aagctagtgg aatcccttat gaaatcggat tagtaaaaaa
     5581 tcaatacatt gcccgaacat ttatccagcc aacgcctgag ctaagagagc aaggtgttcg
     5641 aatgaaatta tctgctgtac gaggagtagt ggaaggtaaa aaggtgatta tggtcgatga
     5701 ttcaattgtt cggggtacga caagcagacg gatcgtccat cttttgaaag aagcaggggc
     5761 aaaagaagtc catgtgagga ttgcttctcc tcctttgaaa tatccatgtt tttacgggat
     5821 tgatattcaa acgcgtaaag aactcattgc ggcaaatcac acgattgatg aaatcaaaga
     5881 atgtatcggt gcagattctt taggtttttt aagtgaagag ggtctgatcg aatcgatcgg
     5941 tctggaaaaa gatgctccgt attcaggatt gtgtatggct tatttcaacg gagattatcc
     6001 gacgccgtta tatgactatg aagaaaaata tcaggaatca ctaaaagaaa aagtatcgtt
     6061 cttttaaaag cagaccaaga agggagtata tgaattcaat ggcaaatgca tacgcaaaag
     6121 ctggcgtaga tgtcgaagct ggatatgaag tagtagaacg gatcaagaag catgtcaaaa
     6181 aaacggaacg tttaggtatg atgggcgcta taggaggatt cggcggttgt tttgatttat
     6241 cggtctttca attaaaagag ccagtccttg tctcggggac cgatggcgtg gggacgaaat
     6301 tagcagtggc aatcgaagca gacaaacacg atacaatcgg gatcgactgc gtagcgatgt
     6361 gtgtcaatga tatcttagca caaggcgcag agccgttata tttcttagac tacttagcaa
     6421 cggggaaaaa tgatccgtta cgtttggaaa atgtagtaaa aggtgtagca gatggatgtg
     6481 ttcaaggaaa tatggcgctg attggcggag aaacagctga aatgcctggt atgtactcag
     6541 gtaatgatta tgatctagcc ggatttgctg tagggatagc tgaaaaatct caattattga
     6601 caggagaaac gatcaaccca ggagatgtgt tgcttggaat agcatctagc gggattcatt
     6661 caaatgggta ctctcttgtt cgcaaaattt tctttgagca gcagcagttt tctttatcat
     6721 caaaactgcc agaattgaaa aaaacacttg gcgaagaatt gcttgagcca acgaaaatct
     6781 atgtttcttc cttgcttccg ctgatcaaag aaaagaaaat aaaaggagct gcacatatca
     6841 ctggtggagg gtttgtagaa aatatcccgc gaatgttacc agaatctatg gctgcacaaa
     6901 tcaaacttgg ctcatggccg attcttccaa tattcggctg tttacaaaaa tatggtgaaa
     6961 ttcctgagat ggagatgtat gaaatcttca atatgggcat cggtatggtc ctggcagtcc
     7021 aagaatcgaa agtaaaagaa atagtacacg aaattgagca agctggcgaa aaagtttatg
     7081 aaatcgggaa agtgatcgcc aaagaaaaac atcgtgtggt gtttatagga gaagaacgat
     7141 gagaatcgct gtttttgctt ctggaaacgg aagcaacttt caagcgctag ccgattatct
     7201 atcgaaaaaa ggattggaat cttcgattga ctggttgttt tgtgatcagc ctgaagcata
     7261 tgttttgaaa cgtgcaactg cgttgagtgt accggcagat tgtttttcac ctaaagaatt
     7321 tgattcaaaa aaagagtatg aagaagcaat tttgcataaa ttgaaagaaa aaaagatcga
     7381 tttgatcgta ttagctggat atatgcgaat cattggaccg gtattgctga aaaattatga
     7441 taaaagaatc atcaatatcc atccgtctct tttacctgcc ttccctggtt tgcatggcat
     7501 acgtgatgcc tttgaagctg gagtaaaaga aacgggtgtc acaattcatt atatcgacca
     7561 aggtgtagat actggaccaa tcatccggca ggaaaaagtg agaattgaac aggaggacac
     7621 gttcgattct ttagaagaaa aaatccatag agtagagcat cgaatctatc cagaagtgat
     7681 tagtgaaatt attgaaaatg gaggctatct gaaatgacaa gagcattgat cagtgtatca
     7741 gataaaactg ggattgtagc attcgcccaa ggtttgattg aacaaggagt agaaatcatt
     7801 tcaacaggag gaacaaagca tgcgttggat aaagctggga tcaaaacgct ttcgatcgaa
     7861 gaagtgacag ggtttcctga aatgatggat ggccgtgtca aaacacttca tcctaaaatc
     7921 catggtggtc ttttaggaag acgcgatctc cctagccata tggaggcaat ggaaacggaa
     7981 aatatccaac caatcgactt tgtttgtgtc aatttatatc ctttcaaaga aacgattatg
     8041 aaaccagatg tcgaaatagc agaagctatt gaaaacattg atatcggtgg tcctagtatg
     8101 ctccgtagtg cagcaaaaaa ccatgaattt gtcacctctg ttgttgatcc atctgactat
     8161 gaagaagtac tttcagaatt acgtcagtat gggcatactt cactttcttt cagacaaaaa
     8221 ctagcggcaa aagtctttcg tcatactgcg gcatatgatg cactgatcgc tcaatactta
     8281 acggattggg tggaagaaaa agaaccggaa aaattgacac ttacgtatga acgaaaacaa
     8341 acgcttcgtt acggtgaaaa tagccatcaa gccgctgcct tttatcagtc cgctcttctg
     8401 gaaaaatatt cgatcgcagc agcaaaacaa ctccatggga aagaactttc ttataataat
     8461 atccgagatg cagatgctgc gctacggatc atgaaggaat atgacgagcc aacggtagtc
     8521 gccttgaaac acatgaatcc ttgtggtatt gggacagcat ctacgatttt agaagcgtgg
     8581 gaagcagcgt atgaagcaga tcctgtttca atctttggtg ggatcatcgt tttgaatcga
     8641 gaagtagatc tgccaacagc agaacagatg cataagctgt ttctagaaat catcattgcc
     8701 ccttcttata cacaagaagc tttggaatta ctgcaaaaaa agaaaaacat ccgattactg
     8761 acagtagact ttgcgcagga agaaaatcaa aatcgagaag aaacggtctc agtcttaggt
     8821 ggacttcttg tacaagatca agatctggca atagaaaatg aagaagagtg gaaagtcgtg
     8881 acaaaacgta agccgactcc agcagaagca aaagcattag cgtttgcttg gagagctgtc
     8941 aaacatgtga aatctaatgc gatcgtactg gcaaacgaac gtcagacagt aggaatcgga
     9001 gccgggcaga tgaatcgagt cggttcagta aaaattgcga ttgaacaagc gcaagagaaa
     9061 atggaaggtg cagttttagc tagcgatgct tattttccaa tggatgattc ggttgaatat
     9121 gcagccaaac atggtataaa agcaatcatt cagccaggag gaagcatcaa agaccaagat
     9181 tctattgata tggcgaataa atacgatcta gcaatggtct ttactgatgt tcggcatttt
     9241 agacattaga gaggagtcgg ataaatgaac attttggtga tcggtgcagg tggtcgtgaa
     9301 catgcaataa gtaaaaaact tttagccagt ccgaaggtgg atacggtgta ttgtgcgcca
     9361 ggaaatccgg ggatgacaaa agatggtatc aattgtgtcg ctatcagtga gcgagatcat
     9421 tcagcgttaa tccattttgt taagaaagag gctattgatt ggagtatcgt tggtcctgaa
     9481 gttcctttgt taaatgggat cgtcgatgat tttatggcgg aaggattgaa aatcttcggt
     9541 ccgacaaaag cagcagctct gatcgaaggt tcgaaaagtt ttgctaaaca attaatggat
     9601 acttatcaaa tcccgacagc taaatccaga agttttgaat gttacgaaaa agcagcagcg
     9661 tatatcaaag aaaatggtgc gccaatcgta gtgaaagcgg acggcttagc agctgggaaa
     9721 ggtgtagtcg tggctaccac agtgaaggaa gcgctggatg cggcagaaca aatgttgaac
     9781 cagcatcgat ttggggatag tagcaaaaaa atcgtcgtag aagagttttt ggcaggagaa
     9841 gaattctccc ttttggcgtt tgtccgtaat accaaggtgt atccgatggt catttcgcaa
     9901 gatcataagc gggcatttga taacgataaa gggccaaata caggcggaat gggtgcttat
     9961 tcaccagtac cgcaaatttc aaaaaagatg attgaaaaag ctgtggaaga agttttaaaa
    10021 ccagcggctt tgggaatgaa agaactagga cgctctttca cgggtgtttt atatgcgggt
    10081 ttgattgcta cgaaggaagg accaaaagtg atcgaattca atgcgcgttt cggtgatcct
    10141 gaaacgcaag tcgttctttc tcggttgaag agtgactttg cgcaagtaat cgatgattta
    10201 ttagagaatc gtacagtaga gttaaagtgg cagcaagaag gatacaatgt aggcgttgtg
    10261 gttgcagctg ccggttaccc cgaagaatat gagacaggaa tggttctacc agattttctg
    10321 gaagaagagc tttctgttta ctatgctgga gtttcctcaa ataacggcaa actagttgga
    10381 gcaggaggac gtctttattt agtagaagca tacggtgaga cgatcaaaga agcacagaaa
    10441 aaaatttaca ccgcgttaat ggataaaacg acagatggaa cattttatcg tacagatatt
    10501 ggagaaaaag ctgccaatag cgaactgatc gtgaagtaaa tcagctgctt ccatttataa
    10561 aaaatacaac aaacataatc ggaagcgccg attttagtga agccttttca taaagagtgt
    10621 ggtacacttt tgttgtgtat ataaataagg aggagttcag atgaaaaaaa ttcaattagg
    10681 tacttctgat cagaaagcag ctgcagtgat cttaggctgt atgcgtatca acaatgcgga
    10741 agatccagta aaagtgattg agacagctta tgaaaacggc attgattttt ttgaccatgc
    10801 agatatttat ggaaacggtg aatgtgaaga aatctttgca gatgctctag caaaaacatc
    10861 aatcaaacga gaagatcttt ttattcaaac aaaatgtgga atcgttccag gtgtgatgtt
    10921 tgatttttct aaaaaacata tcattgaatc tgtagaaaaa agtttgaccc gtctgaaaat
    10981 ggattatgtg gatgctttac ttcttcatcg tccagataca ttggtagaac cagaggaagt
    11041 agctgaagcg tttgatgaat tggaacggtc aggaaaagtt cgttattttg gcgtcagcaa
    11101 tcaaaaacca atgcaaatcg aattgctgaa aaaatatgtt cgtcaaccat tagtagctaa
    11161 tcagctgcaa tttggcttga aacatactgg aatgatcgat caagggattc atgtcaatat
    11221 gacagatgaa gcaagtatcg atcatgacgg tagtgtactt gattattccc gattgcatga
    11281 tatgacgatc caagcatggt caccatacca gtatggattt tttgaaggtg tatttatcgg
    11341 gaacgaaaaa ttccctgaat taaaccaaac attagaagaa ctagcagcta aatatcaaac
    11401 gacaccaact ggcttggctt ctgcttggat tttacgccat ccagccaata tgcaagtgat
    11461 cgccggtacg atgaacgtag ggcgaatcaa ggaaatcgct caagcttcag aaattaatat
    11521 gtctcgggaa gattggtacg aattgtaccg tgctgctgga aacattttac cttaaagatt
    11581 gtcataagca ggtcaaaagg gctataaatt aaaaagacag aataacttga aagctgtttt
    11641 cagcttcgag atattctgtc tttttttatt gcaaatggaa agagtatcat tgtacggatt
    11701 tcgtttatta gttatttttg tttttaagga aaagctgtgt ccgatattct tttggagaaa
    11761 tcccttgttt tttcttaaat aaataactga aatagttagg gtcattataa ccaatttcaa
    11821 aagcaatatc tgaaatacga tagtctgatt gctgcaataa tttttttgct aattcgattc
    11881 tttgttctgt cagataatcg atgaatgttt ggttaaacga ttgagaaaaa atcgtactga
    11941 aatgagaggg acttaatgca acttgttgag cgacccaagt taaggacata tctggatcgg
    12001 taaaattttc tttgataaaa tccaatgcat ggttcaaaat tggctgatat ttgttccttg
    12061 aaggctgtga gggcagagca gttaagaaag aaatgaacat ataaactgtc gaacggtaaa
    12121 gcgagtcgtc ggcgctgatt gctaagcgtt gactggtgga tgtgcaatga accatttctt
    12181 gcgggatttt cttttctttc aggcagacat gctggagtag cttagtcaag acaaataaac
    12241 gatataatcg tgttcgagtt ggtgtgcctt gtggtttcgt caagtgttcg atgtacttag
    12301 atacttcgtt tttcgataat gaagacaaat caagtgagag gtcaaagtaa aagacagaat
    12361 caactggaag tttcgcttct tgaatcaaat cctcatagct gataatttgt tctttaaggg
    12421 aactggcggt ttcaagtatc atctgcgtga tctcaaaaga tgcaggtaat tcgctgattc
    12481 tttctgcgac aggaccaatg gcgacagaaa aattattttt ttgtcccttt tctaattcat
    12541 ggaccaacgt ttgggctacc tgataactgg tctcgatcac attttcttca agagaatcaa
    12601 ctattaaaaa tttgatgaat cgagaggaaa cagcagagaa gatcacttgt tgattctccc
    12661 taaataaaaa cttcaaataa tcactgagat gagcgtaatc ttcaaagtct gtactgactt
    12721 ggtttgctgc taataatacg gtcatttttt tccctgctaa agagcgattg aaagattcag
    12781 caagtttcaa tgtttcactg atcgtaagtg agcctttgaa caaaccgttc aagaaatgat
    12841 tttttttcaa ttcgaaaaca agatcagaag aagtgtgcgt ttctttttgc tgcaaatcta
    12901 aagcagttac tgctttttct attgcttgtt tcaattcgct acttttaatc ggtttaagca
    12961 gataatcatc tgcctgtacc tggattgctc ctttcatata atcgaaatcg tcgaatccac
    13021 taataaatat gagacgagtc caaggaagta gtttccttgc ttcttttgaa aaagtcaacc
    13081 cgtccatgaa aggcatttgg atatcagtca gaatgatgtc gggctgtaag tcgataattg
    13141 aagacagtgc catctcacca tctccagctt cgccgacata agtgattgga taataagaac
    13201 caaggacagt tatttgttcc cgcaagttat tgcgaatgag gtattcgtct tcgatgataa
    13261 aaactttata catgtttgtt tcctccaatt gttttgggag atagagggat catcagtgtg
    13321 acagttgttc cttctcggta tttgctgtca atcgtgatag gtttttgatc atttccgtaa
    13381 taaagaagga gacgcttgtt tacgttgtaa agtccgtagc cgatactgaa atctgaatcg
    13441 atccctttgg ctaactcttt acgtatttct gccagttttt ctgcagggat gccaatcccg
    13501 ttgtctataa ctttgaattg gatcatctca tcaattttgc atgtggtaat acgaataaat
    13561 cctttgtgac ggacgtactt cgttccatgg tatacagcat tttcaatcaa tggctgcaag
    13621 atcattttta aaatagaaac aggaaaaagt gtttctggta tatcgatctt atagtcaagc
    13681 atatggccgt atcttatttt taagatgact agataatcat tgatatggct aatttctttt
    13741 tcaagaggaa tccagtcttg tcctttgctt aaagacgtac gaaaaaagcc ggaaagtgca
    13801 tgggtcatag tcagagcttc ttcaaagcag tcttgttcga tcaaagaaat aatggcatcc
    13861 aaactgttat aaataaaatg gggagtaatc tgagcttgca atacacgaac ttcactttgt
    13921 gctaaatggt attgtttcaa agcgttctcc cgtaaagact ggtttagatc ttccgccatt
    13981 ttattcatgc tagcggtaag tgtttgtaat tccagtgttt ccggcagggt taaacgaaag
    14041 ccaaggttcc ctgaagaaag ttgttctgac atctcgatca gctgattgat cggttcttgg
    14101 acctttctct ctaaaaagcg acgattcttt ttcgcataga aaaaaatggt actaagaact
    14161 ccaagttcca ctattgttaa tagaatgagc gagcggacaa gtgtcgtatt ttttttgctt
    14221 gctaagtcga tctccacacg aacaaaatct tgtaagatat ctgacagcag ttgagtgaca
    14281 gaatctacct gattgatgat ctcttcattg gtatccataa aatcttttgc caagatatta
    14341 ttgatcagct cgttttgata atcttccagt gtatcgatcg tacgtagcga tacatctaac
    14401 gtactaattt ctttaagtgt atttgtatta tttttgatct ctcgaatatc attcctaagt
    14461 tcttctagga tattttcctc attgaactca tctacggtta cttggccaga aatcaagtcc
    14521 cacatacttt ccaaaacttt ttgatcaacc ttcaaagcaa ttgcatctgc tttttggata
    14581 tttgcgatcg tctgttgata aatcaaaagc tgttgcgaat ataacagtat gctcagtagc
    14641 aaagggataa cagcaaatag aagcatggct ttgtttgctt gggcaaaaat ctgttttatg
    14701 cttaaatttt ttgtcatgat acttctccag tcaataattt ctggttggga tgttagctat
    14761 attctgctgg gaaaagacag tctcggaaat aaaaatatct ttaggtaatg tttttcctgt
    14821 ttgaatattt ccaaaataac gagtaacggt attggctaca taccagccga catcaggttt
    14881 acactcgact acacaattga cgattcctga gcgtagcttc tcgatcatat cttcttgtcc
    14941 atcaatagtt acaatgatca aatcttctcc aggtttgatt gatgtttctt ttatcgcagc
    15001 taaagcaccg tgagtcattt catcactatg gctgtataat acatcgattt cggataaatc
    15061 atttgtttct aaatatcgtt tcatctggtc ttttcctttc atccgaataa aatcaccgac
    15121 aattcggtga acaatagtca tcggaggttt atggtcgatg gttccatctt tttttagggt
    15181 tggtttacga ttgattgatt ccaaaaatcc ttcggagcgt agcttggtcg gtgtggagtt
    15241 ctctgaacca gcaagttcta ggattctgat ttcctgtttc tttgaatttg tgaagtgatt
    15301 gctgacaaat aaacccgccc gatttccttc tgctttgaaa ctggggccaa tgtgggtgac
    15361 gaaaagctcg ggatcattcg tttgaatatg tctgtcgaca agtatgacag ggatccctgc
    15421 tcgctttgct tcttttaata cagagtccca cccggattct tgcaaaggag taaaaatgat
    15481 catatccact ttataggcaa tgaacgtccg tatatcttgg atttgccgtt cctgattcat
    15541 gtagccattt cggtagagaa cttggtaatc ttctttttca agcgcagtga taattgattc
    15601 agtatgcttt ttccgccagc tactctccgt tcctgattgc gaaaaaccaa cgactagtgg
    15661 gtcaggtgct tcctttgtat taggtgtaca ccccatcatt tggtaagcga ttacaacaag
    15721 ggctaaaaaa aataaaacac gtttcacttt aaatcactcc atctggattt gttagtacta
    15781 tcttatcaga taaaagggaa aatcaaagtc aaaaggaatc aatcgaaaaa aatccaagaa
    15841 acttaaaaaa atccaagaca aaaaaagtac acctaaaaaa tttaaagtaa atcccataaa
    15901 aaaatcaatg ttaacgcttt ctttattagc tatactcggt gtatcaattg aaatggggga
    15961 taaaaaatga aaaacaaatt tagaaagatt gttgggacta tcgctatttt gaccgcaagc
    16021 attctattaa gtgcgtgtgg caattcagga tctgcagatg atagtacggg gtatgtagga
    16081 atcgctatgc cgaccaaatc agcagaaaga tggatcgctg atgggaacaa catggtctcg
    16141 gaattagaaa aactgggtta taaaacagat cttcaatatg gagaagataa agtagaaaat
    16201 caagtagcac aaatagaaaa tatgattaca aaaggggtag atacacttgt gattgcttct
    16261 atcgatggtt cggctttaac tgatgtgtta gctaaagcaa aagaagcaga tatcaaggtg
    16321 atcgcctatg atcgtttact gatgaattca gaaaatgtcg attattacgc gacttttgat
    16381 aattttggag taggtgtatc gcaagcagct tatattgaag agcacttagg attgaaagaa
    16441 ggaaaaggac cattcacgat tgaattattt ggtggctcgc ctgacgacaa caacgcacta
    16501 atcaattaca acggagtgat gtctgtttta caaccatata tggacaacgg tcagttggtc
    16561 gtgccatctg gacagacgag tttcagtcaa atcgctacgc ttcgctggga tggttctacg
    16621 gcgcaagcaa ggatggataa tctgttaagc gcaaattata ctgaccaaac attggatgct
    16681 gttttgtcgc catatgatcc aataagttta ggaatcattt cgtcattaaa aggcgtgggg
    16741 tatgggagtg aaagtaaacc tttacctgtg attactggac aagatgcgac agttgctggc
    16801 gttaaatcga tcattgccgg ggaacaaaca caaacgatct ttaaagacac acgtatctta
    16861 gcaaaaaata cgattgaaat gatcaaagca atcagtgatg gagaagaggt tccggtcaat
    16921 gatactgaaa cttatgataa tggggtgaaa actgtcccta cgtatttagc aaatacagta
    16981 tctgtcgata aagataatta tcaagcagag ctgatcgaca ccgattatta taaagaatcc
    17041 gatctgaaaa attaagagga accaaacaag gaactaaaga gatctaagtc agagagagga
    17101 taagaattat ggcggattgt attttaaaaa tggcagatat caccaaaaaa ttttctggaa
    17161 tccgagcgtt agattgcgtg aatctgatga ttgaacgtgg ggaaatccat gcattgtgcg
    17221 gagaaaacgg agcgggaaaa tcaacattga tgaatgtctt gagcggcttg tatccatatg
    17281 gctcctatga cggggaaatc ttttatgatg gaaagctgtg tcaatttaaa gatttgaaag
    17341 atagtgaaga aaaaggcatc gtcatcattc atcaagaatt agcactaagt ccttatcttt
    17401 caataaaaga gaatattttt ctcggaaatg aacaagcaga aagaggcgtg attgattggg
    17461 aactgacaga aaagaaaaca tatgaactgc tgaataaagt cggtttgtct atcgacccga
    17521 atcttctagt atcccagatt ggcgtagggc aacagcaact agttgaaata gctaaagcat
    17581 tatcaaaatc cgtccgtctg ttgattttgg atgagcctac cgctgcattg aatgaagaag
    17641 aaagcgcgaa tttgctgaga ttgatccgag agttgaaaga gcaaggtgta acctccatca
    17701 ttatttcaca taagctgaat gaaatcgtgg atatcgcaga tcgaatcacc attttacggg
    17761 atggacagac gattgagaca ctagaaaatg aaatgatcag cgaagagcat attattcgcg
    17821 gaatggtggg cagagattta gttgatcgtt atcctgaaag aaaaccggat attggagaag
    17881 tttattttaa agtagaagac tggacggtct atcaccctct tgatcacgag cgaatcataa
    17941 acgaccacat caacttgcat ttgaaaaaag gagagattgt aggaatagct ggactgatgg
    18001 gagcgggcag aactgaattc gctatgagtc tatttggaca ttcttatgga agcaagatat
    18061 ccggacgtat attaaaggaa ggggcagaga tatcagttaa gaccgttcct tcagccattg
    18121 caaacggact cgcttatgtc tcggaggacc gaaaatcttt aggactgaat ctgctgatgg
    18181 atattcggga aaacgtgacg ctgagcagtt tggataaaat aagtcaaaaa ggagtattag
    18241 ataaagaaaa agaagtaact gaggcagaaa atttccggaa aaagatgcgt ataaaaacaa
    18301 actccatcca tcaaattgtc agtagtctta gtggtgggaa tcaacaaaaa gtcgttttat
    18361 ccaagtggct gatgacacaa cccgatattc tttttttgga tgagccaacc cgtgggatag
    18421 atgttggggc aaaatatgag atctacacga ttatcgaaga aatggcagca aatggcaaag
    18481 ctgtctgtct tatctcttct gaacttcctg aaatattagg gatgtgtgat cgaatctata
    18541 cgatgaacga aggacgtatt acaggagaag tctcgcgaga agatgcagat caggaagtct
    18601 tgatgaaatt aatgacgaaa gaagaggtgg gttaagttgg aacaggcaaa aaatcttacg
    18661 gataaaaaag agaaaaaact aaatttgaaa agtagagcag ctgatctttt tggtcgctac
    18721 agcatggtga tcattttagc gggactactt attgcgtttc aattgatgac ggatggtatt
    18781 ttctggcgtc cattgaatat aactaacctt gttctgcaaa atagccatat attagtacta
    18841 gctgcaggga tgttattagt tgtgctctta ggtcatgtgg atttgtcggt agggtcagtg
    18901 atggcgtttg ttggtgcaat tgcgggcatg atgatggtca atcgccaaat gaacccgtgg
    18961 atgacagtta tcgcatgtct tgcagtaggc gggctgatcg gcgcatggca aggtttttgg
    19021 gtagcttatg cagggatacc ggcgtttatc gtgactttag caggattgct gatgtttcgt
    19081 ggactgacac aagttgttct aggaggccaa tctctagcac cttttccagc tgttttccaa
    19141 aaaatgtcta cgggttattt accagactta agcgaaggaa gcagccttca cttcttgaca
    19201 ttgattttag gaatgatcat cacgatcgtg ttagttgttg gtcaatggcg aacaagaaat
    19261 cgtcggaaaa atcatttatt tgaagtggaa tctccaacag ctttcttggt aaaggcggta
    19321 tttacagcag tcgttgtact aggaataact tatatctttg cctcttatca agggtatccg
    19381 attattttga tcattcttgg tttgatcgtt gcagcatatg ggtttttgac aaataaaaca
    19441 gtagcaggtc gacagattta tgcgacgggc ggaaatcgaa aagcggctga actatcaggg
    19501 atcaaaacaa agcgaatcac gttctgggta ttcgtcaaca tgggagtcat ggcagcttta
    19561 gctggattag ttttagctgc tcgattgaat gcggcaacac ctcaagcagg tacatcgatg
    19621 gaactggatg caatggcggc agtatatttt ggtggtgctt cgacttccgg cggcattgga
    19681 acaatcatgg gtgcgattgt cggtggcttg gtcatgggtg tattgaacaa tggcatgtcg
    19741 attttaggcg tcggggtaga ctggcagcag gcaatcaaag gattgatctt gcttttagcc
    19801 gttgtgctag acttgtataa taagaaaaaa cgaacaacgt aggagaacgc cggttattca
    19861 gaaaaaagac tgtgacaaga catttgtcac agtctttttt tcgctaaaag cgaacattca
    19921 ttgtttcgtt tgtatagact aaaaataata tatgtttttt taccattcgt ataaattctc
    19981 tttttgctct tgattttttt gcttaattga gttaaattac atagggcgct aaaaaaagcc
    20041 ttgattaaat taataatgtt cgtgttttgc tggatgtgaa catcaggagg ataatgtaat
    20101 gaaagtattt gattacgaag atattcaatt aattcctaat aaatgtatcg taaatagccg
    20161 ttctgaatgt gatacaacgg tcacattagg taaacataca ttcaaaatgc cagtagtgcc
    20221 tgccaacatg cagacgatta ttgatgaaac aatcgcagaa ttcttagcgg aaaatggtta
    20281 tttctatatc atgcatcggt ttgatgaagc agctcgaatt ccgtttatca aaaaaatgaa
    20341 aaagcgtgga ttgattacct cgatcagtgt tggcgtcaag aaagaggaat attcctttat
    20401 agagaagttg gcagaagaat cgctaaatcc tgattatatc actatcgaca tcgcgcatgg
    20461 acatgctaac tcagttattg atatgattca gcatattaaa aaatatttgc ctgaaacttt
    20521 tgtgattgcc ggtaatgttg gtacaccgga agccgtccgt gaattggaaa atgcgggcgc
    20581 agatgcaaca aaagtcggga ttggtccagg aaaagtatgt attacaaaaa tcaagacagg
    20641 ctttgggact ggaggctggc aactggcagc tcttagatgg tgtgcgaaag cagctcgcaa
    20701 gccgatcatc gctgacggtg ggatcagaac acatggcgat attgcaaaat ctgtccgttt
    20761 tggtgcgaca atggtcatga ttggttcatt gtttgccggt cacgaggaat ctcctggcga
    20821 aacaaaagtc gaaaatggaa tcgtgtataa agaatacttt ggttctgctt cagaattcca
    20881 aaaaggcgaa aaacgaaatg ttgaaggaaa gaaaatctgg atccaacaca aaggatcttt
    20941 gaaagataca ctagtggaaa tgcaacaaga ccttcaatca tctatttctt atgctggagg
    21001 aagagatctg gaagccattc gaaaagttga ctatgtcatc gtgaaaaatt cgatttttaa
    21061 tggagacaca atctaaaaaa taaataaaat attaggatgt tgtgaaaaag ttgtcctgca
    21121 ttaagtaata agaacagcca aacaaaaata gttctttata tgttttgttt ggctggaatt
    21181 attatcgcag atacaagctt ttgaacatca ttattcagaa taagggactg tgataagatt
    21241 tttgtcacag tcccttatgt tttgcaaaaa aagtttttct tttttctcgt aaattcggta
    21301 aaatcaaaag aaaaaataga caatagaaaa gagaagctta tgtgggaaaa agtagagaaa
    21361 aaacaaggac cgatttatcg tcaaattatg gaacagatta tgagagaaat cgaaaacgga
    21421 aggatcaatc ctggaagtca acttgaatca gaacgaaaac tagggcaact ttttggtgtg
    21481 aatcgttcca ccgttgtcca tgcattggaa gagcttaggg agcttggggt actaacgagc
    21541 aaacgtggca gcggatggtt tgttaatcag actgaatggg ggaaattcgc tgttccaaga
    21601 atcgattggc ggcaaatgat ctctcctcgt tatgagcaga cggactggta tgagcaaaaa
    21661 ataagagaag caaagcagat ccaaaaaaca tcgtttcttg atttatacgc tagcgagatg
    21721 ccagatgagc ttttgccgaa ttttgagttt ccttcttatt ctcttgaaga aatcttagcg
    21781 gaagaaaaag aaatggatct tttaggctat actccgttac gtaacaaaat caaacggtat
    21841 ttggaaagta aatttgaatt ggcattttcc cccaaccagc ttcttgtgac tggtggcggt
    21901 cagcaagcaa tctttttgat tttacaaacg attctttcag ctggagaggg gatagctgta
    21961 gagtcacctt ctttttttta ccgattacct cttttcaaag cttcaggaac gcgtttattt
    22021 gggataccga tggatgaaga agggatcgac ttagaaaaac tgaaagaatc gatccataaa
    22081 aataaattga aagcagtgct tatcaacccg aattttcaaa accctacagg aaaagtgatg
    22141 agtcaaaaac gacgagaaaa gctagtagaa ttgtgtcgac agtatcggct tccaattatt
    22201 gaagacgatg tatttacgga tctttcattt ctaaaccaag aagaagtcct tcctatacga
    22261 acgattgatc cggataatgt gttatacgtc ggttcgttat ctagggtttt aggaaaaaca
    22321 acgaaaatcg gttgggtgat aggacctgag acttttatct cgcaactagc tcaagcgcaa
    22381 gaaatgatgg agttttcgat gaatatcctt acacaaatca cagtggctaa tgtatttaat
    22441 gaagcaattg atttgaaaat gcaagatgta agaaaaaagt tgaaagaaaa aagccgactg
    22501 ataagcgctt ggggagattc acaatcgttt ttcaagcttc attcaatttt aggtggttac
    22561 tatgcctgga ttacttggga tgggaaaaaa ctagaccccg aactagcaga aaaagtagta
    22621 gatatgggtc ttggaattgc accaagtcta ctttttgggc aagatataaa tggaatcaga
    22681 atcaattaca gtaggctgga tgaaaaccaa ataccgttgt tttattcaaa gatgaaaatt
    22741 ctagaaaagt ggttaacaga ataatttcac aaagtaaata gattaaagaa tataacagct
    22801 tggatttaaa tttcaagctg tttctttttt ttcggaaaaa gaatacgata taaagaaact
    22861 aagaaaaaac cattatttgt acgtccgttc acgatgtgta aataaaataa atgtttgcaa
    22921 caaaactgta taacaccaac gtttttaaat agaaacagat ggttgtaagt ttgattagaa
    22981 aatagaaaaa atgcagatga aatataaaac gctttcctta ttgtgatttt attcactaat
    23041 gctgttaata tgcggattgg cataatttcc tttcatcgtg aaaatttgtg cttttagctt
    23101 gtatttctca taaatccatg ataatttatt aatgaagacg gttaaatagt gatacagttt
    23161 tattcactgt ttcaatcgca gaatgaagag attttcttat agatgagaga ggaatgtgtg
    23221 acaaatggca aacaaaaaag caccgatcga cttccaagca ctgctagatg aagtcaatgc
    23281 agatttccca gtatatcaag cacttgatca agatggaaac gtagttaaca aagatttagt
    23341 acctgattta tccgatgatg aactcgttga attaatgact catatggtat ggtctcgtgt
    23401 attagaccaa cgttcaacag cgctgaaccg ccaaggacgc ctaggctttt ttgcaccaac
    23461 tgctggacaa gaggcaagtc agctggctag tgcttacgca tttgataaag aagatgttct
    23521 tcttccaggt tatcgggatg tacctcaact agtaaaacat ggtttacctt tatctcaagc
    23581 ttttttatgg tctcgaggac atgctgcagg taattcttat ccggaagaat tgaaagctct
    23641 accaccacaa attatcatcg gtgcacaata tgtacaagca gccggtgttg cattaggttt
    23701 gaagaaacga aacaagaaaa atgtcgtctt cacttatact ggtgatggcg gttcatcaca
    23761 aggtgatttt tacgaagcaa tcaatttcgc tggcgcttac catgcaaatg ccgtatttta
    23821 tatccaaaac aacgggtatg cgatctctac acctcgtgaa aaacaaactg cagcaaaaac
    23881 acttgcacaa aaagctgtcg cagctgggat tcctggtatt caagtcgatg gaatggatcc
    23941 gcttgcagta tatactgtat ctaaaatggc acgggaatgg gcgatcagtg gaaatggacc
    24001 agtcctaatc gaaacactga cttatcgtta tggaccacat acactatctg gtgacgatcc
    24061 aacccgctac cgtacaaaag acacagatga cgattggcag aaaaaagatc cattgatccg
    24121 cttccgtaaa tatttgacgg aaaaaggact ttggtctgaa gaaaaagaag aacaagtcat
    24181 cgaagcaact aaagaagaaa tcaaagcagc tattgctgaa gccgacaaag taccaaaaca
    24241 aaaggtttca gatttcttga aaaacatgtt cgaagtatct ccacaatcaa tcaaagaaca
    24301 aattgcaatt tatgaagcga aggagtcgaa ataatcatgg cacaaaaaac aatgatccaa
    24361 gcaatcacag atgccttagc acttgaacta gaaaatgacg agaatgtcgt tgtttttggt
    24421 gaagatgttg ggaaaaacgg aggagttttc cgggcaactg aaggattgca ggaaaagttc
    24481 ggagaagacc gagtattcga tactccttta gctgaatctg gaatcgcagg attgagtttc
    24541 ggtcttgcgt tagaaggatt tcgtccagtt cctgaaatcc aattctttgg ttttattttc
    24601 gaagcaatgg acgaagtagt agctcaaatg gctcgtacaa gatatcgaat gagcggcact
    24661 agaaatctac ccatcacaat tcgttcgcca tttggtggcg gtgttcatac accagaattg
    24721 cattcggata atttagaagg tttgatcgct cagtctcctg gtattcgagt agtgattcct
    24781 tccaaccctt atgatgcaaa aggactattg atttcttcta ttagaagtaa cgatccggtt
    24841 gttttcctag aacacatgaa actatatcgc tcattccgag aagaagtgcc ggatgaagct
    24901 tacgaagttc ctttggataa agcagcagtt actcgtgagg gaacagatgt atctattatc
    24961 acatacggag caatggtgcg tgaagcaatc aaagcagcag acaatcttgc aaaagaaaat
    25021 atatctgttg aaatcattga tcttcgtaca gttgcgccat tagatgtaga aacgatcatt
    25081 caatccgtgg aaaaaactgg tcgcgtagtt gttgtccaag aagcacaacg acaagcgggc
    25141 gttgccgcgc aagtagtttc tgagatctca gaacgcgcta tcctttcatt agaagcccca
    25201 atcggacgag tttctgcacc tgatacagtc ttcccatttg gacaagcaga aaatgtctgg
    25261 ttgccaaatg caaaagatat cgaagacaaa gtaaaagaaa tcgcggaatt ttaagaaaag
    25321 aagggacgaa acaaagtcat ggcttatcaa tttaaattgc cggatatcgg tgaaggaatc
    25381 gcagaaggtg aaatcgtcaa atggttcgtc aaaccaggag atacgatcaa tgaagatgat
    25441 acattactag aagttcaaaa tgacaaatca gtagaagaaa tcccgtcacc tgttacagga
    25501 acggttaaaa atgtgattgt tccagaaggt accgtagcaa atgttgggga tgtattagta
    25561 gaaatcgatg caccaggaca cgaagacaat gaaggggaca gtggtgtagc cgcagaatcc
    25621 caaactccag ctaaaccggc tgctgaaccc actgttgata cagaatcagc tggatcgtca
    25681 agcgaaggag tcttccaatt taagtt
//
LOCUS       DAFLVO010000038        24144 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.038, whole genome shotgun sequence.
ACCESSION   DAFLVO010000038 DAFLVO010000000
VERSION     DAFLVO010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24144
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.038"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(44..1339)
                     /gene="purB"
                     /locus_tag="L1U99_001634"
     CDS             complement(44..1339)
                     /gene="purB"
                     /locus_tag="L1U99_001634"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBN1212178.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1352..2476)
                     /gene="purK"
                     /locus_tag="L1U99_001635"
     CDS             complement(1352..2476)
                     /gene="purK"
                     /locus_tag="L1U99_001635"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HBN1212179.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2469..2957)
                     /gene="purE"
                     /locus_tag="L1U99_001636"
     CDS             complement(2469..2957)
                     /gene="purE"
                     /locus_tag="L1U99_001636"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBN1212180.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3373..4680)
                     /locus_tag="L1U99_001637"
     CDS             complement(3373..4680)
                     /locus_tag="L1U99_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBN1212181.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4683..5264)
                     /locus_tag="L1U99_001638"
     CDS             complement(4683..5264)
                     /locus_tag="L1U99_001638"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBN1212182.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5380..5477)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5836..7128)
                     /locus_tag="L1U99_001639"
     CDS             complement(5836..7128)
                     /locus_tag="L1U99_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1212183.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7125..7748)
                     /locus_tag="L1U99_001640"
     CDS             complement(7125..7748)
                     /locus_tag="L1U99_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212184.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7751..8587)
                     /locus_tag="L1U99_001641"
     CDS             complement(7751..8587)
                     /locus_tag="L1U99_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1212185.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8604..9491)
                     /locus_tag="L1U99_001642"
     CDS             complement(8604..9491)
                     /locus_tag="L1U99_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1212186.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9507..10790)
                     /locus_tag="L1U99_001643"
     CDS             complement(9507..10790)
                     /locus_tag="L1U99_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1212187.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11473..12156)
                     /locus_tag="L1U99_001644"
     CDS             complement(11473..12156)
                     /locus_tag="L1U99_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBN1212188.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12174..12791)
                     /locus_tag="L1U99_001645"
     CDS             complement(12174..12791)
                     /locus_tag="L1U99_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBN1212189.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12801..13625)
                     /locus_tag="L1U99_001646"
     CDS             complement(12801..13625)
                     /locus_tag="L1U99_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBN1212190.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13618..14178)
                     /locus_tag="L1U99_001647"
     CDS             complement(13618..14178)
                     /locus_tag="L1U99_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212191.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14352..15308
                     /locus_tag="L1U99_001648"
     CDS             14352..15308
                     /locus_tag="L1U99_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1212192.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15613..16569)
                     /locus_tag="L1U99_001649"
     CDS             complement(15613..16569)
                     /locus_tag="L1U99_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HBN1212193.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16673..17275
                     /locus_tag="L1U99_001650"
     CDS             16673..17275
                     /locus_tag="L1U99_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBN1212194.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17363..18862)
                     /locus_tag="L1U99_001651"
     CDS             complement(17363..18862)
                     /locus_tag="L1U99_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HBN1212195.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18878..19402)
                     /locus_tag="L1U99_001652"
     CDS             complement(18878..19402)
                     /locus_tag="L1U99_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBN1212196.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19700..20449
                     /locus_tag="L1U99_001653"
     CDS             19700..20449
                     /locus_tag="L1U99_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBN1212197.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20440..21225
                     /locus_tag="L1U99_001654"
     CDS             20440..21225
                     /locus_tag="L1U99_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HBN1212198.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21194..21910
                     /locus_tag="L1U99_001655"
     CDS             21194..21910
                     /locus_tag="L1U99_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBN1212199.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22012..23046)
                     /locus_tag="L1U99_001656"
     CDS             complement(22012..23046)
                     /locus_tag="L1U99_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HBN1212200.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(23050..24108)
                     /locus_tag="L1U99_001657"
     CDS             complement(23050..24108)
                     /locus_tag="L1U99_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBN1212201.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
BASE COUNT         7145 a         5212 c         4213 g         7574 t
ORIGIN      
        1 ttttgctatt ctattttaat tgaattttgc aactcactct tctttattcc aaacctactc
       61 gtttgaatat cacgtcaacg tttttcaaat gatgatgata atcaaaggca tcgtctattt
      121 cttctttaga taataccgat gtgatggttg gatcttcttc taacagcggg cggaactgca
      181 cttggttgtc ccaagcgtac gcagtttttg gctgaacaag atcataagct tcttctcttg
      241 tcattccctt atcgatcaat ttcagcataa cgcgctggct ataaatcaaa ccaaatgttg
      301 cagacatatt ccgcttcatg ttttcaggaa agaccgttag atttttaacg atattgccaa
      361 aacgatttaa catgtaattc aataaaatcg tggtatcagg caagatgatt cgttctgctg
      421 aagaatgaga aatatctctt tcatgccata atgtgacatt ttcataggca gtgaccatgt
      481 gtccgcgcac cactctggct agaccagcca tattttctga accgatcgga ttccttttgt
      541 gcggcatagc agaagaacct ttttgacctt tcgcaaaaaa ttcttctact tcacgtgttt
      601 cggatttttg caatccgcgt atctctgttg caaaacgttc aatacttgta gcaataagcg
      661 ccatcgctga gaaatattca gcatgtagat cccgagggag aacttgagta gagatttctt
      721 gtggacggat ccccaattgt ttacatacat actcttcaat aaatggcggg atatttgcga
      781 acgttcccac tgctcctgag atttttcctg cttctactcc ttttgccgca tgttcaaatc
      841 gttcgatgtt ccgtttcatt tctgaatacc atgtggcaag tttcaatcca aaagtagttg
      901 gttcagcatg gacaccgtgt gtccgaccca tcatcactgt atatttgtgt tcttttgctt
      961 tttcgccaat gatttccgta aaacgtttca agtcttcccg taaaatatca tttgcttgct
     1021 tgatgagata gccataagca gtatctacga catccgtact tgttagacca taatggaccc
     1081 attttctttc ttctcccaat gtttcagaaa ccgctcgtgt aaacgcaacg acatcatggc
     1141 gtgttaattt ttcgatttcc aagatccgat cgatatcaaa tgatgcatgc tcacgaattt
     1201 ttttcacatc ttcttgcggg atttcaccaa gttctgccca agcttcatct gctaaaatct
     1261 cgacttcgag ccacgcacgg tatttgttct cttccgtcca gatattcccc atttcagggc
     1321 gtgtataacg ttctaacatg ttttttctcc tctaatccca aatattcgtt tgtttgattt
     1381 cttccagcgt ttgctggatg tcttctgtca agatagtgat atgtcccatc ttgcgacctt
     1441 tttttgcttg tttttttcca tagaaatgga attgccagtc tggcttattc tcaatcaagc
     1501 gatagctttc cagcagttgt tctcccaaaa cattgaccat tactgcattg cttatcaaac
     1561 gtactttttc tcctaatggc caaccacaaa tacctcgaat atgggcatcg aactgactca
     1621 tagaacaagc ttcaatagaa taatgtccag aattgtgagg acgaggagct aattcattca
     1681 catatagccc gcctgttttt gttaaaaaca tttctacccc taaaacacct gaaaggctca
     1741 ctgcttctgc aatcacacgg gcaatacgct cagcctcctc gatcacatcc tgatcaatcg
     1801 cggctggagc aatcgtttca tgaagaatat tgttgtggtg gatgttttcc acgaccggaa
     1861 aagtcgtgaa atctccttga ccatttcctg ccaccatgat cgaaatctct ttttcaaacg
     1921 ggatccatgc ttctaaaaca caggttcctt ctcttaaaag gtccatggca ggagctagat
     1981 ccgcccgact tttcaaaaca tactgcccct tgccatcata gccgcctcga gtggttttca
     2041 aaacacaagg atagccgatc ccgtcaatcg catcttggat atccgtcgga ctgacgatcg
     2101 ttgcataagg agcaatcacg atgttattcg tttccaaaaa agatttttct aacaggcggt
     2161 cttgcgtaat cgcaagcaag tctgtccctt gaggaataaa tgacatgggt aaaatcgcat
     2221 ttaacgcctc tacactgacg ttttcgaatt cataggtaat gacatctgtt cttctggcaa
     2281 gctctttcag cgcaaaggtg tcatcataga cactttcaat gtgccaatct gcaacttgtg
     2341 cggctggaca atcgctcaca ggatccagca cacctacttt aaagcccatt tcttttgcac
     2401 taatcgccat catacgacct aattgaccgc caccgacgat cccgatcgtt gaaccaggca
     2461 acaaaggttt aaccaagttg atcactactt tctataacag ttttagccaa cattgaacgt
     2521 ctttcagcca atttagcctc caattctaaa tcatacatgg aaagcatctg tatcgcaagt
     2581 agtccagcat taattgctcc cgcttttccg attgctgtag tagctacagg tactcctcca
     2641 ggcatttgga caatcgaaag aagcgaatcc aaaccattta atgttcgtga ttggaccggt
     2701 acaccgataa ccggcaaagt tgtttttgat gcgaccatac ccggcagatg cgcggctccc
     2761 cctgctcctg caataatgat tttgattcct ttttttcgag cgttttgtgc atattcaaac
     2821 atcaaatctg gggttcgatg agcagaaacg accttttttt cataagacac accgaattca
     2881 tccaatattt gacatgcttc tttcattgtt tcccaatctg aagtactccc cataatcaca
     2941 gagatttttg ctgtcattgt ttttcctccc agtttttcta cattcatatt ttaacaatca
     3001 ctttttttga tgtcaaagaa atttcgaatg ttaacaaaga aaaacatttt attgttcgtg
     3061 tttattaaag ataaaaaaaa ggaatgtgac aaaagttagg tcacattcct ttttatggat
     3121 aaacggtgtt ctcctgccaa ctcctcggtc acaaggaaca atattcaaca aacatgagaa
     3181 gctttttttt gaaattgttc cttgtgactc ggagatgaac ggcaggctca cgacctcttc
     3241 cttcaacggt gttcaatcag ctgaccctcg gtattagctc aaacaaacgg caaaatacga
     3301 ggaactattt ttccgtttgt ttctctaaca atcaggtcaa aacgctgatt tcacaacctt
     3361 tcttttgctc tattacttct tgaaggcttc ttccaatatt tcttcatctt ttttcaatcc
     3421 attaaagatc aaattcaata tgatagccgt aatgctactc attacgatgc catttccagt
     3481 gaacatttgc aatgtttgcg gcatttgact gaataatgtc ggcgtaacat tgaaacccag
     3541 cccaaatcca acagaaacag caacaatcaa tagattttta tcattgctga aatcaacttc
     3601 caacagcata cggattcctt ggactgccac catcccgaac atgactaaca ttcctccacc
     3661 aagtaccggc tcagggatga tttgtgctaa cgcaccgatt ttagggaata atcctaaaac
     3721 aatcaagaag aatgcagaga aatagatggg ttttcttgtt ttgattcccg aaagttgaac
     3781 caatccgaca ttttgagaaa agccagtata agggaatgta ttgaaaatac cgcctaagat
     3841 aacggcaagt ccttctgcac gatatccctt tttcaattct tcttctccaa catttttccc
     3901 agtaatgtca ccaagtgcaa aatatacacc tgttgattct accatgctga ccatggaaat
     3961 gatgatcatt agtaaaatcg accatacgtc gaaagttggt ttaccaaaat aaaagggttg
     4021 tggaacatgg aacaacggcg catctccaat cgcgctcaga tcaatcattc ccatgaaagc
     4081 agctaagatg cttcctccga ctaaaccaat caataccgcg attgaacgaa tgaacccttt
     4141 tgccagcatt tgcacgccta caattaggag aatcgtcaca aatgcaagta gcagatttgt
     4201 tttgtcacca aaatcagctg ctgttgcatt acctccaccc attttctcga ttgctacagg
     4261 aatcaaagtc aaaccaataa cggtgataac cgttcctgtt actataggag ggaatagttt
     4321 tttaatttta gaaaagacac cagaaactaa cacaacaaag atcccagaag cgataataga
     4381 tccgtagata gctcctactc cttcattggt tccgatcaag atcagtggag ctactgcttg
     4441 gatcgcacat cctaaaacga caggcaagcc aattccgaaa aatcggttaa ctgtcaattg
     4501 caataatgtc gctaatccac acataaagat atcaattgaa atcaaataag tcatctgttc
     4561 ttgattaaag cctagtcctg taccgatcaa aagaggcacc gctactgctc ctgcatacat
     4621 cgctagcaga tgctgcagcc ctaaaaccgc agcttttcca ttttgtgttt ctttttccac
     4681 gattatgcgt cctcctcaag aaactcaact tgtccattcg tcaaggaagc aatacgcgca
     4741 agagaaacga ctctcaatcc catttcttca agtaactgac gtccatcttg gaaagacttt
     4801 tcgatgacga tcccgattcc ttctacttgc gctccagctt gctggcataa ttcgatcaat
     4861 ccttttgccg cttgtccgtt tgccaagaaa tcgtcgataa tcaatacttt gtcttctgaa
     4921 gataaaaatt tacgagaaat agaaatcgta cttgtcactt gtttcgtaaa agaataaaca
     4981 gaagctgtca ataattcttc atccatcgtc aaactttttg cttttctagc gaagatcatt
     5041 ggaacatcta attctcttgc agcaaataaa gctggtgcga tcccagaagc ttcaatggtc
     5101 acaactttcg tgattccttg ttctttaaat acttctgcaa accgttttcc catttgttcc
     5161 atcaatacag ggtctacttg gtgagtgacg aagctgtcga cttttaatac gccctcgcct
     5221 aatatacgtc cgtctttttg aatacgttca actaattctt tcactttatt tgctccttta
     5281 tcatttatta ataccgaaat aaccgctttt gtgcaaaaac ctactatgtt tctgttaaag
     5341 aaaaacaccc tccactttat cataagaaaa gaagggtgaa atagccaatc ttttacttat
     5401 agtccagcat ttacggtact ggctagaaac tgtcatccat attatgacga tatataagta
     5461 ggtatgtaaa actaataata gtgtaaattc attttcttgc aactgttttg cacgtgaagg
     5521 cagtttgcca tatttgaata aaaaatgttg tttcaaatat tgaaaacagt ctaacactac
     5581 tttctgaaac tgacaacgtg gtttacttat ttttttgtaa aatctaatga tttttaatgc
     5641 attattcctt tttgttcggg tttaaatagt tatttttatt ttctcctatc taaaaaagca
     5701 gcccacataa aaagaaggca tgacaaaaag catgtcatag cccctttttc cgaataaata
     5761 gtgttcaaaa gacagcctat cggcaataag gcaagatttt ataaactacg ggaagtaatt
     5821 tccgtaaatc tattcttatt cttttaagct gacaagctcg tcaatcacta ctgcttttcc
     5881 tgaagcaata gaatgatttg ctgcgattcc tgtcaaaatc gacaaaatac catctacgtg
     5941 agttgctgcc cgattccacg gatcttcttc tttttcttca ccaaatagat catctaataa
     6001 acgcggatct cctccgccat gtccgcccgc ttcttgttcg acgattacct catatggctc
     6061 accgaacatc ggatagacat ggatggactg aagaacggct gctccttcat cctttttatc
     6121 tccacctgca ttgatgtaag acttttcgat cactttcatt tcgatccgtc ctttgctgcc
     6181 attgaaagaa acattgaatc cttcccacgg catatacgcg tttagcgaat acgtcaaaat
     6241 cgcaccagtt tcatatttga ccgttacgcc tagtgtatct tcaatagaga tatcatcgga
     6301 aaatacactg cggtcacgaa tatatccact gtctttttct gcttctaaat acatttctcg
     6361 caattcctca ttggctgaca ggtctatagc aaatggatca gctttagcta gttcgcttcc
     6421 atagcatcga ctgtaaaata tttctactcc gcgtttctcc gcattatgca tcccataaaa
     6481 gtttaatcca ccgaatgcaa ataccttttg gggacggctg ttcaaccaaa aattcactag
     6541 atcaaaatga tgggtagatt tatgaacaag aagcccgccg ctattgtgct tatttcgatg
     6601 ccatcttctg aaataatctg ccccgtgttg cgtatttaac agccattcga agtggataga
     6661 aaacacatca ccaatcacat cactttctat cagttccttt atcttcgtgt gatacggtgc
     6721 ataacgataa ttaaaagtga ctcgcaggct tcttcccgtc tgtttttgga ccgttattat
     6781 ttcttgagct ttttcctcat cgatagtcag aggtttttcg caaataacat catatccttt
     6841 tttcattgca cgaatgatat aatcatgatg cgttcgatct actgacgtaa taatgacttc
     6901 agccggccgt acgtcatcca gtagttgctc aaattgtgat ggcatacatg tctttacttt
     6961 tttctgtcca tacttgttca caagtatccg atttgcataa tccatccttg tttgagatac
     7021 atcacaaaaa ccgactagtt cacaagtttg atgatacgta gaggcaattg cctcataaaa
     7081 aaaacgcgct ctcccaccaa gtccgacttg tacatatttt ttcttcattt aaagtcattc
     7141 tccttttctt ttaagcaaaa tactgtgaca aatggcagcc ctggatacag taatgcagtg
     7201 agtaaaaaat catgctgtat acaccagaac agtccataca aaaggcataa ataccacaga
     7261 aaccccttga cgttttttga caacagccag atattccttt tgatcaaata aacaagacta
     7321 tctgctttat cttctttgca gatatcaatt agcgtactaa aaaaactatg ggatacaaaa
     7381 agcaacagac acaatagaaa aggaatcaga taccaagctc caatctttcc cactaataaa
     7441 taccaatcaa ctgcaaaaat aatgacaaac agctgaaaca acgtaatgat gaaacacatc
     7501 cgtttgattt ttcctttcct ccaacatacc tttttttctg ccaagtaatg gacagataga
     7561 taataagaag gatacatcat caaaaaataa atcagataga caacacgagc agacagcact
     7621 aatcctaaag tgaacaaaca tcctagaact aaagcgaaaa gagcattact gataagactg
     7681 gttaaaaaaa tccgacagac atagtagttg agcttgtaaa gaaacatctc ttctattggc
     7741 tttttcatat tcagcccttc agaccgcttg tactgatccc ctggacaaga tatttattga
     7801 agaataagaa aatcagaaaa accggtagca gcgacaacgt agacatcgca aacatactcg
     7861 cgtaagtcgt actagatcca gcgtctgcaa ataatttgat ggcaatcgat accgtgtaag
     7921 atctcggctt gtttaaataa atcaatggtc ccatgaagtc gtcccatttc caataaaact
     7981 ggatgatgat cgtcgtgatg atcgaaggtt tcagcaaagg aaaaataatt ttggtaaaga
     8041 cactatactt gctgcatccg tcaataatcg ctgattcatc taactctttg gggatgctga
     8101 ccatgaattg catgatctgg taaatgaaaa atgcttgtcc aaaaaaatgt ggtaaaatca
     8161 gcggcacata cgtcccaacc aaattcagcc gattgtaaat aataaactgc ggaatcaaaa
     8221 tcacttgtgc aggaatcatc atcgttacta acatgacgac gaaccagaat ctttttcctt
     8281 tgaaatcgat tctcgataat gcgtaagcaa tacaagtcga gctcagaact gtccctatcg
     8341 tcgaaactgc agagatgaca aacgaattcc taaagaaagt aaaaaatgaa attccagcaa
     8401 accccgccca tccttttgcg taattttccc attgaaaagt ctctggaatc aaattcagcg
     8461 aaccactcat aatctcttga tccgttttaa aagaacctgc gatcatccat aagaccggat
     8521 aaatcatgac tagacctaat agcaaaataa aaccgtattg aaaccatttc gttactgtat
     8581 tattcatttc ttcctcctct cattcacaca acgacccatt tttttgatga tttgaaaatc
     8641 agaaaggtga cagctcccat aatcaacagc atgatccacg aaatagcact agcatacccc
     8701 atagaattaa aagaaaaagc ttggttatac acataaagag cataaaagtt cgtggcatca
     8761 ttcggaccac cttgggtaat gataaatgcc tgcgtaaaag tcataaacgc cgcgattgtc
     8821 tgcataacca agttatacaa aatgatcggc gaaagaagag gtaacgtgat cttgtaaaac
     8881 gtctgccatt tgttcgctcc atcgatctct gccgcttcat aatacgagcc tgggatctct
     8941 ttgatacctg cagcaaagat gatcattgcc gaaccgaatt gccaagcaga catcaaaaca
     9001 agagggatca tgaccagttt ttgatcgcta aaccaggaaa gcgcaggtgc gcctaatcgt
     9061 tccaggaaaa tattcactaa cccgttttta gaaaacaact cccgccaaac tagagcgata
     9121 gaaatactgc caccgatcaa actaggcaca taatacaaag aacgaaagaa agtcgttcct
     9181 ttgatattcc tcgttaaaag ataagcaatc aatagaccaa agatcagttt cacaggtaca
     9241 gatgcaaata catagagaaa agtgactcgg atggagttca aaaaacgggc atcactcagc
     9301 atctttatat aattatccaa gccgatccat gagactggat ttcccaaacg ataatcggtg
     9361 aacgaataat aaagtgacaa gatcatcggt atcactgtta tcaatagaaa tcctaggatg
     9421 aatggagaag caaatacgta accgaccaca ttgtcttgat ccaagaaccg ttttagtttt
     9481 tcttttttca tgccttcctc ctgctgctat cctagaatgt ttgacgcaaa ctcataaaga
     9541 ctctctgctg cttcttctgc tgttacttct tcataaatga ctttttcaac taaaagattg
     9601 tattggtctt gaatttccgg attcaaagca ctatcaaaga cattcacttc gccgttgtcc
     9661 atatcggaaa tcatttctaa ataatcaaat gtcgcttgca aagttgcatc atctgcacga
     9721 gcgagctgtt ctcgaatatt cgacatgatt ggtacaccac gttctccttt taaaatttca
     9781 ttggcttctt cactgttttg aaagaaatca ataaacttag cagcttcttc tttatgggct
     9841 gagctttttg ccatactcag catttgcgaa gaacgtaaag ggataccaga ttctccatct
     9901 gcttttctgc gaggtggatt aatcaactga atctccatat cttcaggagc ccctgacaat
     9961 atttctgtca actggttact tgatagaaac accattgccg cttctctatc cctaaccgcc
    10021 tgaaaagaca gatccgtcgt acttgcagct ccaccacctg gttctggatg ggcccctttg
    10081 tctaccagat ttttacgcag ctggaaaaaa tctgttagat agtctggatt ttcaaatccc
    10141 aagctgttag atagatcttc ccgattataa aaattcaatc ctttctcaac ttgtggtatt
    10201 tgaataatac agccagctat aaaatcttcg aatcttgaaa tagcatagat tcctaattct
    10261 tcagtgattt gatagctgat ttgttcaaat tcatcccatg tccaatttga agctggttca
    10321 gggatattta attgttcaaa tatattttta ttgtaagcaa tcgcaaacga attcaccccg
    10381 ttagacagtc caactaattg cccgtcgtaa gtcgtcgttg ctaaatagga ttcatctgca
    10441 ttagaaatat caattatccc ttgctccaca tattcatcta atggttcaat ctgattgatg
    10501 tattgaggaa attgattgtt cagttggaaa atgtcccaga tatcatctga tgctgctagt
    10561 gtacctaatt ttgtgtaata tccttcataa tcataaaatt cataatcgat cgtcacatgg
    10621 ggattttttt cttcataaag ctcgattact tttactgttg catcgtgtcg gacttgcgaa
    10681 ccccaccaag ccatgttcag cgtgattttt ttgtcatctt cttgcccaca agccgtcaag
    10741 aagaataaca taacacttaa agctaagatg attctcattc ttttcttcat tctctgcacc
    10801 tctacttcca ttgttatttt tcaatatact gtatttttat acagaacata tttattaaac
    10861 gatctttttc aaggggaata aaaaccaaga cttgccttat cgttctgcct aggatgaaca
    10921 actcaatact ttcaagaaaa attagatagt gctgattctt ctttcatcgc taaaaacact
    10981 tcttgcttca atgatgggag gataattacg caaagaaaaa aggatatcag acaactgccc
    11041 aatatccttg acatagctaa ataagcatgc ttcttcgtgt gcgctcttcc ctaaaaaaca
    11101 gaaaaataac tagtaattct gtatgaaatt aggtacaata tacacgtcga tgcacaagca
    11161 ttgactatgg caacttgatt ggtcagttcc cgctgacttt tcaagccccg acaatttagc
    11221 tgctactaaa ttgtcgggtg ccttttttag tttttattcg tttttcattc tatagaaagc
    11281 gcttcaataa atcaagacat ttttttgtta gaatgctaat aataacaaaa ggttttaact
    11341 cttcttatgt acattacagg taaaaaaaca aaaaaatttc tctttttttt gaattctgaa
    11401 caaatagtac tggagtacaa aagacgagga agagccacta tctgctcttc ctcgtctttt
    11461 gattctcacc tgttattcat gattcttttt ctcagtttcc cgatattttt ccattttacg
    11521 actaaaaagc tctccgctac ttggtggcgt atatgtgatg gcatttgctc ctgcttgaat
    11581 ggtctcagca atactttctt ccgttggacc acctgtcgca atgataggaa gttcaggata
    11641 ttttttacga aaatggcgta ctgcttctgc agtttcttta cctgcactga tattgataat
    11701 cgaaatacca gctgctaact tttcatctat ttctgtatat ttcgacgtta ccgtactgat
    11761 aactggaata tcaactactc gacaaacttc ttttactgtc tctaaaggcg taggaccgtt
    11821 caaaacgacc cctaacgaac cttgcgcttc tgcgaacatg ctcatgtagg aagaacgagc
    11881 accttgtgtc aaaccaccac ctacaccgga gaaaactgga atgtcagctg cctcaataat
    11941 gcttttagta atcgctggat gaggtgtaaa aggatacaca gcaattactg cattcgcatt
    12001 tgtattacgt atgatcgcaa tatccgtagt aaagatgatc gaacggatca attttccaaa
    12061 tatcttgatc ccgcttgctt ctaaaatgat ttccggtact cttacgatat cttttctcaa
    12121 ttccgtcatg atttctggcg taaattgttc tgccatcagc cacttctcct ttgctatctc
    12181 cggtcatact gattcaattg atacgtctcg atgacctgga tgattttttg cgcataaccg
    12241 gggtctgtcg cataacctgc atcttgcaat gcttgtgcgg cttcctgata gttggtggcc
    12301 gtaatcactt tttcatacag cgcaggattc caatctactc cttggacgaa cagttgtgta
    12361 tggtcatcca tggactgttc ccatgaatca tacactttga agtctccttg gatagttatc
    12421 cattcttcgt taacaaattc ctttgtttcc aggcttactt tcttctgatc cccataagcc
    12481 ttgatcccga aaagattatt gtatttgcta gccaaggtac tttttcccca atttgattct
    12541 aatatagctt gtcctaaaat gatactagga agcactccat aaccatcttg tagttcttgg
    12601 gcatgcggaa caagccgttc aataaattgc tgatgggatt gcgcttcatt ttcttgctga
    12661 ttatcagtaa aaggagaaga cagattcttc aaggaaaaaa caaaggctaa gagtatcact
    12721 gctacaccgg caaccactgc tggccaacgg atattcttgc gcttttgctt tttccacttt
    12781 tttttcgcca tgatcaattc ctacttttca tttaattcat tcagatattc ttctagcgtc
    12841 aattggtgtt tggtgatata ctcagcgttt tctttaccga cataacgtaa gtgccaaggt
    12901 tcatatgtga tcttagttat atcttcgtgt ccttttggat aacgaacgat aaatccatac
    12961 tgcgcagcat tatctgcgat ccatttagct ccaggctgat ctccgtaact tgcatccaat
    13021 acagtagaag gataactgtt gtaccagttt tgatcgacga catcgactgc cagacctgtg
    13081 tggtgttcgc tgtatcctgg ctccgtaatc gtttctttag taatctttgt cgcctcctct
    13141 tctgatacac cttgacgact catcacatct tggacatttt gttcgaaaac ttgttgttgg
    13201 gatgatacag accggtaagc tgagaccatc actaatggaa atccagctgc ttcagcagcc
    13261 ttggcaaatg cttcatattc tggagcaatg cgtttgtcga tcaagtatcc gttacttaat
    13321 gatgccaatt gagtagactc atcaatttct ttttctaatt tgtgatctgg accaaccaaa
    13381 actagcttcc aatcgtctgt tttaacatct ggcaattgtt tggacgtacg atcttttgtt
    13441 tctttgtcct ttaccttgct gctggttgtt tgactgttct tttctttact agcagttgtt
    13501 ttggtgcttg ttcgttcgac tgcttgattg ccggcttgaa catgcgaatc atcatcgcta
    13561 aaaataacat agcccattgc tgcgatcata atcacaactg ctccaaatcc taaaaattta
    13621 ttcacttgaa aaatcctttc gttgttcttc acgttcccca ttcgcctcat gaacgtaagt
    13681 ttcttccaga ttttcattca cccaatcgag aagttcgatt ttttctcctt cgatctgttt
    13741 ttgaacatct gctggcagac gaaaattcaa aatatcatca tagccccatt catcatattg
    13801 aatacttact ttcaagtcaa ggtatctacc agcctgctga ttatttttca aagggatcag
    13861 ctcgactttt gctgctttgc tgctaagcca tttttgcgcg atgcgtgttt tgatttgctt
    13921 gtactctgca acggcaacgt ttcgtttttc gggaaaaata atcgtttgac gcaaaatctt
    13981 ttgcgttagc atccattcat aatcagtgaa aagatttttt actttctgca tcgcttcaga
    14041 tggcagattt ttctcgccat ctttccattt ttgccattgt tctggactga tcagcaagta
    14101 ttcatctaaa aaattttttt cagtttcaaa ctgttctaat aatacactca taataagatc
    14161 aatatatact tgatgcacgt ttatcccctc cttttaacta ttctacttaa gttttgatca
    14221 aaaagcacct cttaaatcgc tgctttcatt ttttttaatg tttcaagtcc tctcctcttt
    14281 attcttcgtg atttttgtta taataataga cagacaagaa actcaatcca actatgaagg
    14341 agcgttttca gatgaaaaaa tatcaatggg gaatcgttgg tcttggtacc atcgcacatg
    14401 agtttgccga aagcttcaat caagagacga gcgaactaac agcagttgct tccagaactt
    14461 cagaaaaagc ggaaaacttc gctcaccgtt acaatattcc aaaagcttac ggaagctatc
    14521 aagaaatgtt agacgatgct gaaatcgaca tcgtgtacat tgctgtacca aatagacagc
    14581 atatcgacca tatcttggca gcattggaag caggcaaaca cgttctatgt gaaaaagcca
    14641 tcacgatgaa taaaaaagaa ctggctgacg ctatgcgctt agcagaagaa aagaatttga
    14701 tcttagcaga agcgatgaca atcttcaaca tgccacttta tcagcagtta cgctcaataa
    14761 tggatacagg aaaactgggg gctttaaaaa tgatccaagc acctttcggc agttacaaag
    14821 aaccagaccc taaaaaccgg ttcttcaatc cagaattagc tggaggagct ctgttggata
    14881 tcggtacgta tgctgtatct ttcgctcgtt tctttttgag ctctcaacct gaagtagttg
    14941 cctctacaat ggttcctttt gaaacaggcg tggacgaaca atccgtcact atcttgcgta
    15001 acaaagaaaa tgaacttgct gctgtcagct tgacttttca ggcaaaaatg ccaaaagtcg
    15061 gtatcgttgc ctttgagaac ggttatgtga cgattgctga ttacccgcgt gctgatcgtg
    15121 cggagatctt atttacagat ggtacaaagg aattcatcga aagcgggaat acatctgaag
    15181 caatgaatta cgaaataaag aatatggtac acatgattga aggtgacttg cccaatcgct
    15241 ctctcttctt gacaaaagat gtcatcgaaa tcttggatca aatgcaagtt ctatggaaaa
    15301 atatgtaatt ttaaaaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
    15361 acaaaaatag ctcctcctat ttttcgtttg gctggactta ttaccgcaga ggaaagcttt
    15421 tgaacaccgt ttaagaaaga ggttgtgagc ctaccgttca gctccgagtc acaaggagca
    15481 atttcaaaaa acagcttctc atgtttgttg aatattgtga cttgtgaccg aggagttgac
    15541 aggagaacac cgtttaaaga agaggttgtg aaatcagctt tttgacctga atattagctg
    15601 aattcacaac ctctattttt ggattttttg ttgggagaat tctgccttga tttcaataaa
    15661 acttttaaaa gactgcaaaa actggaacaa ttctgctcga tcctcgaatt cagggcgact
    15721 agtcggcaga ggcatttgcc gatacaatac ataaacttct tcaatacgtg ttaaaatttg
    15781 tctgccatca tttgactctg aaaatgtttc tgcagtataa atcaataaac catagatatg
    15841 ttttccataa taagctggtt gctggattct ctctagattt tccagcatgt ctttaatcac
    15901 attggcctgt gctcttctca tagagaagta agtttcgtag tatagcggct gtctgagcca
    15961 gtagttttct tgatgttctc tggcatcttc ttggctttcg cgaatgaatg tcagtaaatg
    16021 ttcgcatttg atctgcacat cttctttatt ttctgataaa agaaattctg ccatttgtct
    16081 caaaatattt cgaaattctt tttcgatctg tatttggttt tccttcagct gcttcgtacg
    16141 atctggcatg taaacatttg caagcaaagc aaatactaat ccaatcgcca ttaatcccgc
    16201 ttcattgccg atcagctgcc aagacatgtt ttcctccact aaataatgag tgaccaaaac
    16261 cgaatttact actatccctt cggttaattt gaagcgagag gcaagcggga tgaacaggaa
    16321 taaaaaaaga ctgaagccaa aaatagtata cccaacagca aaaaaactga acagtgctgt
    16381 tgccgtagct aatataaagg ctgcgattcg attcatgccc gtacgcaatg tagagcgctt
    16441 ggtatttcct acacttaata atgcaatgat ccctgcagct ggccaataca acagcgataa
    16501 gctacccgct gtgaccatcg aaaagaagac actgatcact gttttgactg ttcgcattcc
    16561 tatacgcatt tacttccccc ttttttattt taattatact tgaataatga aaaactagct
    16621 atcagacaaa agtttaggta tgatagtaaa aagaccaaaa aggagaatct ctatgcaatt
    16681 tggccgtttt cgactaggta tgcgtacgat caaaagtgcc ttagctgttt ttttatgtat
    16741 cttgtttttt catttgactc aacgaggaat cccgatgatt gctgcattat ctgctgtttt
    16801 ttctttgcgt caggacttga ctacaaccgt ttcttttgga aagtctagga tcatcggcaa
    16861 tacattaggt ggtacattag ctatcattta tttttttgtc aaaagctatt ttcacaatga
    16921 ttttttggta gaattgatct tgcttcctat tctagttatt attgtgatcg tcgtgtcaga
    16981 tggtattaac aataattccg gtatcatttc cgcaatagct acgttgttgc tgattgcgtt
    17041 gagcatccct caaggcgaat ccgctttgta tgctatccaa cgtgtactag atacttttat
    17101 agggacattc attgcaatcg gtatcaattt ctttcttcgt cctcctgaaa cagaaaagaa
    17161 ggaagaacta tcagaagatt tggtcgaact ccaaaagaaa gaacgattgc taagaacaaa
    17221 tttacaagag atagaagcta agatccaaaa acaaaagaaa aatagcgagg actaattttc
    17281 ttttgcaata aaataaaaaa atggagagaa gaactttaaa aagtcttcct ccatttttga
    17341 ttgaacggtg aagtgtacta ctttattctt ccttcatcga gttttgttct gcctcttttg
    17401 gcgcttcata catatttact tggctagtag tcccacgtgt cgacaaattc tctacgattt
    17461 ccttcaagtc aagtcctgtt gtcgctttta gtgtttcttg agtagaagaa agcaaatttg
    17521 tggcataatt tgtcactcgg ttcgctccac tggtttctcc tgaactgctt cctgtatcga
    17581 caacagagat tttttcgata tttcctagcg gctgtgctgc ttcgcgcatc aattgcggta
    17641 gcatatcgat aaccatactc aagacagctg cttcgccata ttccttgaag gcattggcga
    17701 tcttttgttt tgcttcggct tctgcttttc cttttgctag tgctgcttcg gcttctgctt
    17761 gtccagctaa acgtgtctta ttggcttccg cttctgccag tgcttccaca cggaatcgtt
    17821 ctgcttcggc ttcagtcact tctttgactt tttgagcttg tgcttcttgt tctttagcgt
    17881 accgatcggc atctgctttt ttcttcactt ccgaatcata ttgcttttca cgacgtgtga
    17941 tttctttttc ttccagttcg atttgttttt gacgttctac gattttaatc tgcatttcct
    18001 gttcgattac ttgttgttgt gctcgggcac tttctaaatt gtaggcttgg tctgcttttg
    18061 ctttagcaac atcttgttct tgtttgtagg ttgctaattt cagttctttt tcttttaatg
    18121 attctgcgat ctctgtttgt cgctgtaatt cagctgcttg tgattctttt tctgcttgag
    18181 cttttttgat acgcgtttct tttagagctt ccgcttctgc tatatctgca tctcttttga
    18241 cttgggcgat tcttggtttc cctaaagagt caagataacc gtttttgtct ctgacctctt
    18301 tgatagtgaa agaaacgatg atcaacccca tttttgcaag gtctacagaa gcgacttctt
    18361 gtacgctttg actgaactta tcgcgatttt gatagatttc ttctacagtc atagaaccaa
    18421 gaatcgagcg caagtgtcct tctaatactt ctcttgcttc attttccagt tcttctcttg
    18481 tcttgcctaa aaactgttct gctgctgtag caatctcttc tacagatgaa ccgattttga
    18541 tgatcgaagt accatcacac atcaccggta cgccttgttc cgtatacact tcaggggtgg
    18601 agacgtccaa tttactcgat aatagactga tccgattcga acgttgaaaa actggcaaga
    18661 cgaatgcgcc acctccacgc acaattttga ttttgttatt gctttcatca atgtgcacat
    18721 ttttgcttcc taaataactt ccactgatga tcaacgcttc atccggtttt gctgtctggt
    18781 acttcgctac aaagacgatc agcaacatca gtaaaatcaa agctgcgatt gcgatcgcga
    18841 taaaaacaac tggtatttcc atttaacaca cgctccttta agcttttatc atgctttcat
    18901 aaggcatgac ataacagatt ctttccttga tctcaatgat caatactttc gttccccgct
    18961 cagctgtctg ttcttggggg ctgtaaaaac aagctggacg actaatggaa ccggtaacac
    19021 ttttcaactg aatttctccc atacctcgta cagggatcgg tgtgatcaca acagctactt
    19081 gtccttccag agttttttca gaagacgaca tcgttgattc ggcatgtttc atcggcatca
    19141 atatatagaa attaagcaaa aataccaaca ctatcgatat gcctccacta gcaataaata
    19201 aaaataaaga tgattgatct gttaaacgct cacctagaaa accaaataag cttgtgaaag
    19261 ttaaccaagg gataataagc atcggatcaa gcgggccatc aaaatcgaat acatctccaa
    19321 aaataatcaa taggactgcc aatcctgcac aaatcagcaa tgtataccaa taaatcgtct
    19381 caagtgcgat tccccctatc atatacacgc ctccttccat ttctacgtct atcataccaa
    19441 tgtttgaaaa ttctgtatag cttcttttac cgactcagtg gtgtttttta taggaaggtt
    19501 gtgtttatcg ttgacaattt gttaaatttt tgttttcatg ttaaaatttt cacaataaat
    19561 tctttcgagg tagcctatgt ttcctttttt taagaaaaaa ccattaaagc tccagaacac
    19621 gatcatcctt gtcgtttgtt tctccacatt cgtttctttg attgtttctg ccatattgat
    19681 caggaatttt attctttcga tgaaccgatc tagtgtgtca gataaaatct ctagcattgc
    19741 taaaatcgtt gccaatgata aactcatcca aaaaaagctg cagactggtg acccgacaca
    19801 tgcgattcaa ggaataacaa atgaaatcat gattgcatcg aatttagatt ttatcgttgt
    19861 catggaccct gaaggcattc gatattctca cgcagaccca agttacatcg gtcttccttt
    19921 ctcaagtcat gaagatgtga aaaaagtgat tggaggacaa gaatttttct ctgaaaaaga
    19981 aggaatgtta gggttcggct tccgctattt cgtccctatt tattatgatc aagagattat
    20041 tggtgcagtt tgtgttggct taacaaacaa cacgattgac aatcaagtca aagatggaca
    20101 aaaaatgatt gttttttcat tgattattgg acttagcgta ggcatcatag gcgccgtttt
    20161 tcttgcccaa aaaatgaaaa aagtactgct tggacttgaa ccacaagaaa tagcagaaca
    20221 gttaagtgaa aaaacgatta tcgaaaatga agtagatgaa ggaatcttag ccatctcttc
    20281 tgataaaact atcctcttga tcaatacacc tgcaaaaaac attttctacc aaacagagca
    20341 gctattggat ttcgaagtag gaaaaaaatc agtgataatc tatatgacgt tttgtttaaa
    20401 gagacgattg agcatcaaac gaccgttcgg actcaatcca tgtatttaaa tgggatagaa
    20461 actatttcta gcgttacacc tctttttagc aatgaccgtt ttttaggagc agtcgcaact
    20521 ttacgaaatc gatcagaagt aatgaaatta atggaggagc ttggggggac gaaacaatat
    20581 ataaactcca tgagagctca aacccatgaa ttcatgaata aacttcatgt catttctggt
    20641 ttgattgatt tgaagaagta tgaagaagtc acccatttta tccagcagct aaatcaaaat
    20701 tataaaaaag agattggcca agtctcaagt ctgatcaaag tacctgcaat tgccggtttt
    20761 ttattaggca aaataaacga agccaaagaa caatctgttg aaatgctgtt agaaagcgat
    20821 tcttttatcc ctaaaatgga gatggatgac tccatccatt cacttttgca agtgttaggg
    20881 aacttacttg ataatgcaaa agaagccgtg ctacaaaaac atgaaagaaa cggacaggtc
    20941 cggattcatt taaactatga cacagaagct gaagtattca tcgtgaccgt ctgcgatgac
    21001 ggtgtcggga tatcagaaga aatctcagaa aaaatattta cgctaggttt ttcgacgaag
    21061 ggaatcaatc gtgggtttgg attgaatctc atccattcaa tcgtcaaacg ccacggtgga
    21121 tttttagaat tttccaaaca aacaaatggc ggtacaatcg tctatctaga attaccaaaa
    21181 aaggaagatc aaaatgatga caaatgtcct gataatcgaa gatgatccaa tggttgcaga
    21241 attgaatcgt acttttgtgg aaagcatccc taatatgaac gtaatcgaaa gtttcagaaa
    21301 tgtagaagaa ggaaaaaaat atttcagaca aaaaaacgca gatctgctgc tgcttgatgt
    21361 atacatgcct ggcgaaagtg gtatccattt tttatcttgg cttagacagc aaggaaatga
    21421 tatcccagtg attttgatca ctgctgcaga tgatatcgaa accataaaga atgtgatccg
    21481 ctacggtgcc ttagattatt tgatcaaacc gttcactttg caacgttttc agctggcgat
    21541 cgaaaagtat cttgctttct ctcagacaat ccaaacgact gaaaaagccg atcagaaatt
    21601 gatcgatcaa gtattcaacc acaccactcc cattcacgaa ataccatcat tcatcgattt
    21661 gcctaaaggt ctgtcaaaac tgactttaaa aaaaataagt gcatttattc taaaagaaga
    21721 tactattttt tcaacaaaag aactggctca aaaaagctca ctgtcacgta tatccgtcaa
    21781 gaaatatttg aattttttag tagaacaaga tatattgaac gaaagaatca aatatttgga
    21841 aatcggccgg ccgctaacct gttatgaatt gacaaagaat gggcggaaaa agctcacaga
    21901 ttactgttga gtcatcgaat tatcccatac aaaatagtcc aagtatacag aagtaacaac
    21961 tgtttacttg gactattttt aaacatttta ttgacgaata tccatgtttt cttatcttaa
    22021 ttgacgggct ttaggaagag atacctcatt tttcgttttt ccagtttcta ttatttcacg
    22081 aaagttctcg aaacttgtcg aaatcatatt tgataatgcc tcatctgtat ttgaacctac
    22141 atgcggggtt acaagaactc tagggtacat ttctactaat tgctggatag cagggtctgg
    22201 aatcgtctcc catggcttga aggatcggaa aaaaacctct gtttcatttg caaaaacatc
    22261 ggttgcaaaa ccagctaaat gattgctttt caaagctctt aaaatagctt cattatcttg
    22321 aagctctcca cgggctgtat taatcaagat gctacctttt ttcatttgag ctaaaaatcc
    22381 ttcattgatc atttgatcgt tttcacctgg gatatgaggt acatgaatac tgacaatatc
    22441 gcttttggct aataactctt caagcgagtg gaacgtcaat acttttttag cagcttctgt
    22501 ctgatgaata tcgtagccga tcactttggc tcctagtccc ttaaacaaaa cagcttccgt
    22561 caaccctatc ctgcctgttc ctatgatccc tactgtgcaa tttctgattt cacgactaaa
    22621 catttgctca tccactcgaa aatctttgaa agatgttcgg atcgtcgtat acgcagtatt
    22681 tctcaaaagc atcatggcaa aagtcaaaga taactctgct atcgcatttg gcgaatacga
    22741 tggtacacgg gctactgtca taccaaaatc agctgccgct tgtagatcga tatgattgac
    22801 tcccacagtc cgtgtaaaaa cataacgaat cccatattcc tgcatttttg caagattggt
    22861 ctcatctgct atacaatttc ccctcaacaa tacagcatca tggtcctttg ctgacacgat
    22921 attgtcatgt gtcaacagtt cttcataaag actgagatca taatggtaaa tattcaattt
    22981 ttcaaaaaaa tctatctcgt tcggacgaac accgtaacat gcgattctca tactttcttc
    23041 ctccatttct tatgaaaata aacctatgcc atgaatcatt tgtaatacaa cgatccatac
    23101 aggtgtcagt accacagcaa aaatagttga cagtaaggat gcattggagg ctaaaagtgc
    23161 ctccctatca aaactgatag cataggctgc tgccactgtt gcagctggtg tagccatcat
    23221 gataacgatt gttgccagtg cttcaaaatt gactggtaga atattcgttg ccgtcaaaac
    23281 tgctagaatc acgatattca atgcaggtac aaataccact ttgactagac tgtaatacca
    23341 tgaagttttt tcagatgcag cttttttgaa gcttacttca cctaatgttg cgccgattgc
    23401 tagccacgcc aatggtgaac ttaaaccagc taaataatcc atcggctgaa atagccacgg
    23461 tgcagtctgg tcaattcgca aaaacgctac ttggcttatc tctccttctg cacctgtaac
    23521 tgacacttgt ggcagatacc cttggaacag ccaaatgaaa aggccggcaa aagtagcgat
    23581 aatgattgga ttgacgaaca tcgctttgat atttttagct tccatcttca agccactcat
    23641 ttttatgtat ccataagaat acaaaaagat tcggtagcca atattgaaaa ttgaggaata
    23701 catcacgccg acaggaccat aaatcgcact gacgataggc gttccgaaaa aggtcgtaga
    23761 accaaagatc gtcaggacac gcaacgttgt ttgcttatcc cctttatagc ttaagaaaaa
    23821 aggttttgaa actagaataa gaataatata aataactaat ccccaaatca agacattgat
    23881 tccttgcatc agtaattctg tattgatatc ttgcatgaaa gctcgaaatg ccagtgctgg
    23941 caaagccact gttaagacga ctttcgatag aatttttcca acagattcag aaaaaatccc
    24001 cttttttcta caaacaaacc ctaataatat aataaaaact gttgaagtga ttgcactgac
    24061 aatcgacata tctgtcaaag tcgatcgaaa aatgtcaaat aagttcatct ttctcctcct
    24121 aattatgttc atttattcac aata
//
LOCUS       DAFLVO010000039        24001 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.039, whole genome shotgun sequence.
ACCESSION   DAFLVO010000039 DAFLVO010000000
VERSION     DAFLVO010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.039"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(1237..1902)
                     /locus_tag="L1U99_001658"
     CDS             complement(1237..1902)
                     /locus_tag="L1U99_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1212202.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            2082..4064
                     /locus_tag="L1U99_001659"
     CDS             2082..4064
                     /locus_tag="L1U99_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBN1212203.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4068..4706
                     /locus_tag="L1U99_001660"
     CDS             4068..4706
                     /locus_tag="L1U99_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1212204.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            4734..5162
                     /locus_tag="L1U99_001661"
     CDS             4734..5162
                     /locus_tag="L1U99_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212205.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            5619..6530
                     /locus_tag="L1U99_001662"
     CDS             5619..6530
                     /locus_tag="L1U99_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBN1212206.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            6747..7184
                     /locus_tag="L1U99_001663"
     CDS             6747..7184
                     /locus_tag="L1U99_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212207.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            7279..8163
                     /locus_tag="L1U99_001664"
     CDS             7279..8163
                     /locus_tag="L1U99_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBN1212208.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            8387..11554
                     /locus_tag="L1U99_001665"
     CDS             8387..11554
                     /locus_tag="L1U99_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212209.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            11574..12119
                     /locus_tag="L1U99_001666"
     CDS             11574..12119
                     /locus_tag="L1U99_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HBN1212210.1"
                     /translation="MNRIWNKSHRNNCSLLMILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILI"
     gene            12147..12602
                     /locus_tag="L1U99_001667"
     CDS             12147..12602
                     /locus_tag="L1U99_001667"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HBN1212211.1"
                     /translation="MKLKKAYADQSDGRNVIKANLQNPNASYMFGLTTSVEIYKKETK
                     EPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKGAWKEKRWNLHTDFEITD
                     DAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFILKERRKKK"
     gene            12599..13357
                     /locus_tag="L1U99_001668"
     CDS             12599..13357
                     /locus_tag="L1U99_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBN1212212.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(13443..14183)
                     /locus_tag="L1U99_001669"
     CDS             complement(13443..14183)
                     /locus_tag="L1U99_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1212213.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            14244..15497
                     /locus_tag="L1U99_001670"
     CDS             14244..15497
                     /locus_tag="L1U99_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBN1212214.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            15819..16046
                     /locus_tag="L1U99_001671"
     CDS             15819..16046
                     /locus_tag="L1U99_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBN1212215.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            16169..16495
                     /locus_tag="L1U99_001672"
     CDS             16169..16495
                     /locus_tag="L1U99_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBN1212216.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            16563..17276
                     /locus_tag="L1U99_001673"
     CDS             16563..17276
                     /locus_tag="L1U99_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBN1212217.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            17586..18436
                     /locus_tag="L1U99_001674"
                     /pseudo
     CDS             17586..18436
                     /locus_tag="L1U99_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            18557..20422
                     /locus_tag="L1U99_001675"
     CDS             18557..20422
                     /locus_tag="L1U99_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1212218.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            20470..21879
                     /locus_tag="L1U99_001676"
     CDS             20470..21879
                     /locus_tag="L1U99_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBN1212219.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            21987..22688
                     /locus_tag="L1U99_001677"
     CDS             21987..22688
                     /locus_tag="L1U99_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1212220.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            22847..23326
                     /locus_tag="L1U99_001678"
                     /pseudo
     CDS             22847..23326
                     /locus_tag="L1U99_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
BASE COUNT         8085 a         3919 c         4943 g         7054 t
ORIGIN      
        1 actacctgta ttagtcctct tttttgacca gattttgacc agtctatttt acattctaat
       61 atattcatat gagctaattt tatgattaaa tggtaagtgt ttccttgttt gttttagttt
      121 aaactagtgt gtaatttaaa aatctatatg gaagggtctg tggggtaata cttaaataaa
      181 ggctaggaac ctgataacat caaggttcct agccttttta taataaaatg aagcgaaaat
      241 aatttctttt aaagagccga gattatcagc tatataagag tgaatttgat gcaaaaaaca
      301 gagccgaaac agtcttggtg ttcgtagctc tgcttatatg tttcgaattt aagacaaaga
      361 gttggcaaaa gatgttgata aggaagataa gataactgtg ttatataaac taggtaacta
      421 actgtaacaa gctaatttta agagattctt attagaagac gtttaggaat ataactaaga
      481 aaatgattat acaggtaatt gtcatttcaa taatgttttc taattttcgc gtctttgttt
      541 taagaaaaag gccagaatca gttggaaaaa agttcgtacg atagtgaaga ggggcaaaat
      601 ttcctactaa tattcccact aacaagagat aaaacggcca ggttggtgtg attcctctat
      661 aaaaaaatgc ccatgctacc gaaatcccat agattaacaa ctgaacaatt tttacaatga
      721 aaaaattgtt ctgccattac tcaaagtctc ttcctccttg tatcgtttat ttgtttcatt
      781 ttatcattat gataggcgct tgaacaatcc attttgtatt ttattgagta ctcttggata
      841 aactaccagc gattatcata tttatttatg ttactgtaag ccatcatata aaagtaaatg
      901 agcagatcat agaaatataa aaaagaacta aaattgatct aaattatgtg cagcttgact
      961 acgtaccaat ctatattact tactagattg gtcgttaatc tattcggatc gaatgagcaa
     1021 aatatttttg tgaatgtcca tccttgatta tgattccaaa aagaatcatt gggaggctgt
     1081 ggcgtaaata ttatactata agccagaaat acctatcatt ctgaactttt ttatttagga
     1141 actttcatct caaggctttt tcaattaatt tgtacccctg ttttttggat aagatcatgt
     1201 gcattgattt tttctatctc tacgttcatc tcctacttaa tgcctatctg gctcctgagg
     1261 gcttcttttt aaggcgtcgt catagtcttg gctgaggatt tcttggtaat ctgagggaat
     1321 ggcttcccaa gtgagcaggc gaacgttcat gacgtgtttt cctttgtgtt tgattacagc
     1381 atggtttttc tctttttcta cctctccagc gtgaaaagac agccatgtac catggccaaa
     1441 gatatcatta catacccaac gttcgatgga attgtccacg tatcctacag ggagtgtggt
     1501 atagccgatt tgtggtttca aaaaaggatt gaatcgatcg atcgtttcat ttttgtattg
     1561 ataattgata agaaaaagat agaccaaaca aaagacgagc agaaagaaag atagtgtctt
     1621 tttgagtgag aagggttgtt ttgatgaata agatttcttg ttaacaagag gttcatctgg
     1681 caatgttggt tctattgatt cggtagctga ttcaatagaa ggaaaatcaa tcggcagacc
     1741 taaagtatga tgtaaaagtg acagcatttc aaggtctggc attgtacgag aattttccca
     1801 actagaaatc gttttatcgg aaacaccaat tttttcgcct aattcttttt gcgtaagctt
     1861 acaatttctg cggtaagttc gtattttttc tccggtgttc atcttcttct cctttcgatt
     1921 ctacagtata tagatttatt ctacatgacc tatacacttg atagatacgt ttttttgatg
     1981 aaaaacggta tgattttatc aaagaatcat ttaagtaagg gagagtggtg ataatcaaaa
     2041 aaaagttcac agttttactc acaatcatag tgaccggtat catgagtggt tttgccttgg
     2101 ttagtataaa taaacaggta ctctatcgga caaatgaatt tttccatcaa acagatactt
     2161 atactccgat tcgattgcca caacatttta ttgggcaaga agaatatgag cagctaatca
     2221 tggtatttga aaatgtctca tcagaaactg agctttctta tatgaaaaaa acagtaaatg
     2281 aatccaatga agtagataca tcttggaact tcaagataca gccaaagctt gaaatgacat
     2341 tgtattatca aggggatgtc aaatcttctc acgagaaggt accctattct aatacctcct
     2401 ttcgcgtaac gtccattgaa gaatcgatca aaataaaaga ttttgaaggt gaatttttct
     2461 tgatgacgag agaaaaagaa gcctatgaac ggttcatttc actattcact gatcgattca
     2521 atcaagcatt tcacactgat tatgccacta atatttttga agactttgaa aatagctatt
     2581 cgtattcggt tatttcaaat acagacgtat ataattatcg agtgtattta actattggat
     2641 tgattctttt attccttttg ttatcatcct ttttcttatt gatgaataaa gaaatcagtt
     2701 tattgttgaa taatgacttt tcattacatc aagtattgtg gtgtttattg gggaaaaaga
     2761 aaatcattat tacattcata attgcaggaa tcattggtgg ttttattttt atgtattata
     2821 aggagcaatt tctttatttg ttccagatgt acgttttctt gttcagcgga atatatggta
     2881 tctctttgat ttctctttta ttagttgaaa aaatcgcttc gttaagagaa gcgttcaact
     2941 atatccaata cattcttttt acatttggat tgttgttttc tcttcttttg accgttgcca
     3001 atgtcgaatt agcaactatc gttttttctt cttcacagtt agctgtttcc catgaaccac
     3061 caaaagaaat cgctggtgag gactatcatg tattttatcc agtaaccatc gggaaaaacc
     3121 acgtggattt tatttattcc aatcgttttg catcagcagc agatcaggaa ttatatgaaa
     3181 ctttgaataa aaacggaagt atattagtca atgtatcaga ttacttgaat gaagaaaatg
     3241 aacagtttgg cagagggata aaaataaatc tgaattatct taagaaattt cctttgattg
     3301 atgtctctgg aaggttgatc caaataaccg aaaaagaaac gcaccctgtt atattgatcc
     3361 ctgaacgata tagacataca gatttaaaaa atgacctggc gcaaataaca gaatattatc
     3421 aagaaatcag tgaaaaagaa ccgaaatttc tatttataaa aaacaatcaa cccatttata
     3481 catttattcc ttctatcccc tggatcgaac attatccggt tgttgaaata ctgacattga
     3541 aaaacagtat gtatttggaa agaaatattc tcagcggaga aatctatcca ccgttaaaga
     3601 tcaagatagg ctctttgtcg aaagaaaggt tatttgagct gattgaagaa agtcagttac
     3661 gtgataactt gcagttatca tttccgtata ctcagactga agagatagct gtcaaagtgt
     3721 taagcagatc atttcattac ttgatacaga tatttttact cactttcttt tctttcttct
     3781 tgttgagcta tgtcatgtta tgcatatatt ttgtctacaa ttgtcggaaa atcgctatct
     3841 ttcgttcaag tggttattcg ctctttgaaa cgtataaaga tttcttcatg atgaacctca
     3901 tcaaatgggg aacgacaagt gtaatcttcc tttttcttat agaaagagag cctaaatatc
     3961 tttttaatat ttttttcttt agcttcattg attttattct ttcagttgtt tttattttgt
     4021 ctacagaaaa gaaaagtcag ttattgctga tgaatggagg ttaacaattg gagccgttga
     4081 tagtgataaa aggtgcgaaa aaaatcattc gaaacaaaac gattcttcat ttggatcgtt
     4141 tcactgcgga tgctggggat cttgtgactg ttgttggaga aagtggagca ggtaaaagta
     4201 cgttattgaa tatattagga ttgaatgatc agttcagttc aggacaattc tatttgttcg
     4261 atcaagagac gaaacaatta actgggagag agaagcgctt gataaaaaga aataccatat
     4321 cttttctttt tcaagatttt gggttgattg aatatgaaac aatcgatttt aatttagata
     4381 ttggattgaa gttttcgaat ttaaatgttt cagataagcg aacagcaaag tatgaggcat
     4441 tgaaaaaagt aaatataaac aagaagctaa gtacgcctat ctacacatta tctggtggtg
     4501 agaagcaaag aatcgcctgt gcgagagtct tattgaagaa tagcaaaatc attttagccg
     4561 atgaaccgac tgggtcattg gataaaagaa ataaggataa agtagttgaa atcttatcgc
     4621 aacaagcttc ccaaggtacg ttagttatcg tagtcacgca tgatccatat ctgaccaaaa
     4681 taggaaacaa gaagatcatg ctttaaaaat caaaaaggaa aggatgtcgt tttatgaaaa
     4741 aagcagttat tatttgtgca ctagggatag gttttgttgg aggaaacgct atgtcatctg
     4801 aagtggaagc aaattcagtt cacggtgaaa tctattacaa atctttaaag ccaggagaga
     4861 ttcattttga tgctaaaggt aatattatta agtcaaattt accagtagac cgggaaattt
     4921 ctagaacagc aattaatcat agctctggaa gatgggttta ttatagtgat acaacttgta
     4981 cgagaaaaac aggtcattct aaccactata gtcgtgtcta taatcgtcac ggtgcaaaag
     5041 cgaaagttgg aaactctatt cgatcagcaa atgcaacaaa aggagtatgg gcctatgcaa
     5101 gtgcgacagg aaatagaact gacacattct catgttggta caatccaacc ggttggtatt
     5161 aagtatccaa aagtttatat aaaatagaaa aaacatataa tgaaacagcg ttaaaagtta
     5221 tttttggtag ttttaatata ttcattttta gttgtataaa aatatatcat aataaaaaca
     5281 acaaaaaaat gtctggaaaa tcgaacataa aagtgtctga tttgaatatc ccagcagcgg
     5341 aagaagaaaa acaaaatcga taacatttgt tctaagaatt agttacgtta aatacggaac
     5401 gcaagataga cttgaaaaac ggtaacaaaa gaagtagtat attaaggtgt gatgtgctac
     5461 ttgacattta ttctgctgag cgaactttct ggattgtgta gccttatatc tattcaggac
     5521 gtatcgagca gattagtaaa ggtgttcttg atgattttca tcttgaacac ctttgttttt
     5581 agcaattcgc aaaaaacgaa aagtaggaga attgataaat gaaaaaaaga tttttagcac
     5641 ttgccatcgt actaggcact ggcttattgt caggctgtac gaatgccggt gaaaaaacag
     5701 ccgttagtta taaaggcggt acaatcagcg aacaagaagt aatggatagc ttgaaaaaaa
     5761 tgcaaggagc agattccgct gtgcaacagt tgatcgttta tcaagtattt gaagataaat
     5821 atggagatga cgtatcaacc aaagaaatcg attctcaata tgatcaaaca aagaaacaat
     5881 tgggtgattc atttgattca caattgaaat ctgcaggtta cacagaacaa acattcaaag
     5941 acagtatcaa acaaagtcta gcctttcaag aaggtctaaa gaaacatatc aaattgaccg
     6001 atgaagattt aaaaacggct tgggaatctt tccatccaga agtggaagct caaattatcc
     6061 aagtagcaag tgaagatgat gcaaaagatg tgaagaaagc tgctgataag ggagacgatt
     6121 tctctaaatt agccaaagac aagtcaactg atactacgac aaaagaagat ggcggaaaag
     6181 tgaaatttga ttccactact acaacggttc cggcagaagt caaagaagca gcctttaagt
     6241 tgaaagatgg tcaagtttct gatgtgatca cttctaccaa tgcttcaact tatactacgg
     6301 aatattatgt ggttaaaatg gtgaaaaacc aaaacaaagg caacgacatg gataaataca
     6361 aaaaagaatt gaaagaaatt gcaacagaca caaaattaag tgacagtacc ttccagaata
     6421 aagtaattgg cgaagtattg aaagacgcta atgtaaaaat caaagacaaa gactttgaaa
     6481 atgttttgag tacattcact tcagattcta gtacagcaag tagtaaataa gcggtataaa
     6541 taaaaaatat gaactattta aatcaataaa actgttcatc taaatctttt tattagaact
     6601 aaatcaacag tagtttaatt actacttgat ttagttcttt ttattttaaa aatttttttt
     6661 acttagaatc cagcgaccct agatattttt ctgtataatc ttaaataaag aaaacaatat
     6721 caaaaaatgc acgtagaagt agataaatgg agtggttttg caaatttctt ttatttctag
     6781 aagttattca cgtatacgga tttgtttttc tcacaaataa aaaggcagga agtacaatgg
     6841 atcatttgta tataaaatat attcatcaat tttccgtttt ggtgttaggc acactaatta
     6901 tagcggggat tgtcgcattt attattcaag gccgtgacat attaacagta catcaagagt
     6961 ttttcagtta tgcatttggt attcctctga tcgctataag gtctgataac aaaaagtgga
     7021 agaaacgcta ttacattctc ttgctatttt tgtgttttta tctgccacct aagattttta
     7081 ctttattagg tatacaatgc ctatcatttt cttttatttc ctatatcatt gttttaattt
     7141 tcctcagttt catagtatgg atgttttatc ttgtcaaaaa ataaatgaat gtttcatgaa
     7201 cagtacttca tcacagccta atttttttct ttatgctatc gttatattaa agaaatcaat
     7261 cagaagggaa agaaagtgat gaaaaaagtt ttattagtgg taaaccccag ttcaggcggt
     7321 gaacaagcaa aggaatttga gcaattagcg atagcaaaat tggaatcggt gtttgatgaa
     7381 gtggtcgtct tgcatacaaa aaaagcaggg gatgcaaaaa actttactcg cgaagcggct
     7441 acggaagggt atcatagtgt gtttgtcatg ggcggagatg gaacagtcaa cgaaggaatc
     7501 agtggaatcg ctgaacaaga acatcggcca aatttcggat ttttcccatt gggtacggtg
     7561 aatgacttgg ctcgagcatt agggataccg ctagaacctg aggaagcgat caatcatttt
     7621 tcgattgaat cagtcaagcc attggatatt ggaaaaataa atgacgacta ttttatgaat
     7681 gtcgtcgcaa ttggctctat ccctgaatca atcaatgatg tagatgcgga gaagaagacg
     7741 aaatttggaa aactagctta tttcatgtca ggaatcaaac agttagcttc cacacaatcc
     7801 tactcgtttc acgtagaagt tgatggaaag aaggaagaaa ttgagagcag taccttgctg
     7861 ataggactaa ctaactcagt cggcggtttt gaaacattac ttccaaatgc aaaagtggat
     7921 gatggtaagc tccatttggt ttatttaaaa gattcttctt tgatcgatac gcttaaaaca
     7981 ttgccagacc tattaaaagg agtagatgaa tctacgaaaa atctagccta ccttacttgt
     8041 gagcaattag ttgtgtcatt agctgatgag gaagaattga cgacgaatgt tgatggagat
     8101 gaaggggata aattacctgt gacaatcaaa gtattgccct cacatttaca ggtttattgt
     8161 taaaatggag gttgtgaccg aggagttggc gggagaacac cgcttgttcg ggataaggga
     8221 ctgtgacaag acttttgtca cagccttttt tttgtacaaa aaagaaattt acacctaata
     8281 gaaaaatttt tccataaaaa tacatatttt aaatatgaaa gtacaattgg aaatagatta
     8341 aaacgataaa ataaaattgt caaaacgtca gagaggatgg tggagaatga atcaatgtgt
     8401 aaaaaagctg attgcgtcga ttttgtttgt cttccctctc ttgatggtga catccgtttt
     8461 tgccgatgta gagaaaacaa acgaatcaac gcaatcagag aatcaaagtt ttgacaagac
     8521 tactttttca gaagaatcga ttacttctga aactacagaa tctcaaagtg aggcttctac
     8581 taataaaagg caagaagaaa ataagacaag tgagacctca gaagtagctg aacaaacgtc
     8641 tgatagcagt gaagcggcac tggcaagagc tgtttcagcg gatgggtaca gcgaagctgc
     8701 cacaacagaa gaactggcgc agcttctcgc agacgaatca gtaactaaga tccgactgat
     8761 tcagcctttg actttagaca gggaattaga gatcaaacga gatatcgtta ttgattttgg
     8821 tggattcgct cacaatttcg gcacacacca tatttatatc aatgagatac ctcagtcgat
     8881 cgagttccag aattttaaag gaacagctgc acatccaggt ggattgacac caaatatcga
     8941 tggaaatgcc attatcattg cttatatgac cgatttttgg ggaagcagat atcattttac
     9001 gggagaaata aaatttaccg ggacacttga tttgtatgat gggtccaaat taggactgat
     9061 ttacgctcct cgtgcaactg tcacattaga tggtgtttcc ggtgtgttgg atgtccaacc
     9121 agtgaaggaa ggactgaatg ccgctccggg taaagcctat ttttgtagaa gctatcaatt
     9181 gaatgtgatc aatggtagtc aactttatgg accgtatcta gggaaattct acggttttct
     9241 agattcagga gatgagactg gtagtggaaa aacagcgcca ggaatccata tcttaagcgg
     9301 ttcaaaggtc tctcttgatt atgatcgggc agatggcgtt agcgatgaag gagaggcagt
     9361 cgatacgcta cctggtaatg tcatgtttga agtcagtggt tcgggaagcg aattttcggt
     9421 aaatacaaag atcaatatta ccaatgacaa caatcgcgga atcatccaaa tgagaggttc
     9481 aggatcgaaa gtcactgtat cgaatggtgg gaaaatcacc atcaatacag caactacggg
     9541 cggatttcgc ttgcaaggag attctagtca aatccatgta tcaagtggtg gacaaatctc
     9601 ggtcaaaatg gctggagatg acgatcaacc cgggaacaat gggatgcgtt ttgtaggaaa
     9661 aggcctttct ttgatcgtag aaggagccgg atcagttatc gacatcgata agcagagtgg
     9721 gcgttccagc gcagttcgtt ttgagaatgg tacgcaaaag ctgacagtaa ccaatggagg
     9781 ctcattgagg gtaagaaata caggtgatgg caaatcttac gtgaacagac tcaatcaagg
     9841 aaatcaagcg atccaatttt atgacgcttc tggttttcta gaaagtccag gttcagctga
     9901 ttttacagtc actggagaaa aatcaaatat cgatatacgc gcagattccg gagcaactgt
     9961 agatacaact ggagatattg atttaaattt tacggcaggt gaaaaaactt atttagtcat
    10021 ggtcgggaaa acaggggaag ataagaccgg catcatcagt ggggatgtgt tgaatgtgga
    10081 cttagaatct cctacctatt ttgatttcca aaacaaacgg attggaagcg agaccaatgg
    10141 cataggcggc tgggtattcc aaggaaatgg agattcttct ttaaagatcg cccattcaga
    10201 aatcgcttta tggcgaaaaa caggcgcaac attcgataac tttgaaaaag acccggatta
    10261 tttttctgat atgacagact tatcgatcaa tgggaccgac ttaggcaatt tcgtatcaag
    10321 ccctagtgca ggtttaacaa atgaatttgc tcagacaggt gccggaatga aaaattataa
    10381 tcgaatcagt gccaataatc agctcccgat gattgaatcc ttaagagtgc caacgaatgc
    10441 agataaaaaa atctatgggc atgtcgttgt tcccgaaggt gtcgaggcaa agccaagaga
    10501 tgcttggaca ggcgaagtag aagtgacttt acgtattact tacgcagata cgacgaaatc
    10561 atctgtagaa attactgctc tcacgcaagg acaaacagat gaaaatgaag gggcaggata
    10621 taacccatgg ggagaaggcg aacaaggcgg cttgttcgaa gttcaagtac ccaatgatga
    10681 gagattaaaa acggaggatc aagtgcaagt tgttgctgct aaaaaagtaa gaggtggcca
    10741 agaagtgaca gaactggact ctgccaaaac gacagtcgat gtgattcctc ctgaacctgc
    10801 taatttaagt accacattga tcaatgcagc ttctcgcacg atcacaggta caggtgaagc
    10861 aggagccttg gtttcattga aaaaaaatca agctgttttg tcagaaacaa ctattgatga
    10921 tacaggggaa tttgttcttt ctatcccaga aaatcaactt tttgcaggag atgtattaga
    10981 aattgtatta aacgaccaag caggagaagc tactgctaag ggtgtgcaga acaagccaag
    11041 taccaacgat gaaattggga atcacaatcc aagtgatacg ccagttgttt atcatgatgc
    11101 cccgcctttt gcacctgcta cgaagatcgt agtagaaggt ggtctctcat ttcttgcccc
    11161 ttccaaactc gattttggtc agatcaaagc aactggtttg acacaagaag catttggcca
    11221 aatggatata caggaaaaat tatggattta tgatcagcga gaaacgaaaa atccgtggat
    11281 cttaacgata aaattatctc agcctttcac aaatgatgca ggattttcta tgcaggatgt
    11341 cctatatttc aagaaaggag aggagtatca attagtgaat gaagaagaac tggaaattgt
    11401 cagaggacaa aattcaacga atgtgcaagc agattattca gaatatttaa ataacggtcg
    11461 ggcgtttaaa cttgtcttaa ccaaagaaaa tcagatagct ggtaattact cagcagagat
    11521 aacatggaca ttagcagatg cgccgacaga ataaagatca aggaggatga ttgatgaatc
    11581 gaatatggaa taaaagtcat cgaaacaact gctctttact tatgatcctt ctccttggat
    11641 tcatcctttg gcagacacct gtccatgcct ccgaattcaa ttttgcggta gattttgaat
    11701 taccggctaa tcagattgat aagaacaaaa catatataaa tgtaaggatg gagcctggga
    11761 aaacacagga aatcccctac acggtcttta accgaacaga taaatcagta acagttgaga
    11821 cattgatcca ctccgctacg acgaattcaa acggtgtgat cgaatatgga gaatcaaaaa
    11881 gtaaatttga tgaaacatta agttatgata tgaaaaactt agcaaaaaca gtgggagaaa
    11941 taactgttcc tcctcaaagt gcggtcactg agacactttc actgaaagcg ccagaaaaag
    12001 agctggctgg tgtggtcgca ggagggatca cgtttcaaga aaaaaaagag aacgtttcta
    12061 acaaaagtac agttggtgtc gtcaatcagt tttctcaagt gaaagcaatc ttgatttgaa
    12121 atagcgaaaa agagtcttcc ccagatttga aattaaaaaa agcttatgcg gatcaaagcg
    12181 atggaagaaa tgtgattaag gcgaatcttc aaaatccaaa tgcttcttat atgttcggct
    12241 tgactacatc ggttgaaatc tacaaaaaag aaacaaaaga gccttacctt tcaataaaaa
    12301 aagaaaaaat agatgtagca cccaatacaa attttgattt acttgtccca ttagaaggaa
    12361 aaaaattagc tccgggacat tatcaagcgg ttgtgaaggg tgcttggaaa gaaaaacgct
    12421 ggaatctcca taccgatttt gaaataactg atgatgcagc ggaccaattg aatgaaaagg
    12481 atattgattt aaaaaatcag ccagaaacat ttgactggcg atggctgata cttgttggag
    12541 tcattcttat tggcttattt gctggattat ttattttaaa agaaagaagg aaaaagaaat
    12601 gaaaaaaaca attgcattaa gtaccgttct agctggaagt ctattattat gtacacaaag
    12661 tgtttttgct gagaataaga gctcagccac tacagaagga acgatttctg tgaccaaacc
    12721 agatgctgca aatcctgaag acgttgttcc agttcctcct gttgatccaa atgatcctga
    12781 tactcctttt acacctgacg aaccaaatca gggaacatcc ggattactga cgattgacca
    12841 agctccagat cttgattttg gaacaatcaa gttaggtaca gcaaaaacag tatatgctgc
    12901 attacaaagc ggaacggaca gtactggagc acaaacacaa gtacagaatt tcgtacaagt
    12961 aacggataaa agcggaaatt atgccggttg gaaattatca gtcaaacgaa cagaatttat
    13021 tggtacaaca tctgatacga ataaactaac tggttcaaag gtgaaattca aaaacgccgt
    13081 gattcgaaat agcgcaacta atagcagtgg aatgccatct accgtttctg gaactggcgc
    13141 tgaaggaatc gaaatcccag cagatcaggc agtagatcta gtaactgcag gagcaaatga
    13201 agggattggc acatggattt attcattagg agagaatgtg gaacaaggga gacaatcagt
    13261 ggaattattt gttcctgtat ccaattatgc tgtagacaac tacgtttcaa cattcacatg
    13321 gtcgttaaca gatgctccta cagaagagga agcgtaaaat catatcaacg atttcaggga
    13381 gtggagccga ttcaaggccc actccctgaa atctgctatg cttacgtctc agctcttatt
    13441 catcaactcg aagcagtttt ttggaagtca tggaaacgtt cctttgtctt ttcaaagatc
    13501 tttcgaccaa cgagtaagga gtcaccgttg aaaaattcta acacataatg agcagaatca
    13561 attttctgca attgcgataa gttgatacag taagatttta aaagtaaaaa gtaagcatac
    13621 ttttctaact ctgtcttcaa ttgttttaaa gaagtattca ctaatttatc ttctgtagtt
    13681 gttttgacca taacttggtt tttcaaacct ttgatacttt caatatataa aatttcccga
    13741 ggatacagga cgagacttcc acctttttga tcaataaaga ttttatcgac atttacgatc
    13801 tgctgttctt tccaattgat ctgttctagc acttgacgaa tttgttcaga taaattcctg
    13861 tcttttctga tatatccaat cggaaggatt ttccgattga tgatctctac tgcaaaattc
    13921 gtataagcgg tgaaaaaaac aatattacta tgtgcatttt ttttacgtat ttgttcggcg
    13981 acatcaatac ctgtgagtga ttgcttcaag tcgatatcga taaagaaaac atcgtgatta
    14041 tcaatagtgc ccaactggat caactgattg atttgagaga tagaagtgag ctgcacgata
    14101 ttctcgatat gatgattgac caattctctg atgatccatt cgctgtgaaa ctggttatct
    14161 tctatgataa aatacttttt catatgcagg ctcctattaa aaaaatatgt gtacattttg
    14221 aaacaaaaca atggaggaat aagatggtcg caacagtgac actttatttg acctttactt
    14281 tgattttaga tttaggtatc tatttattct tttcgaaaca actgctagta aaaaacagct
    14341 ttggttgtat agctttgatg gtggtgacac ttttacttcc tatccctaaa gtgagctttc
    14401 cttacctagt tggcttatta ttgatgtttc ttttttattt tactacgaaa aacctgttta
    14461 tcagctgttt gatcagtaat cttttttttg ctatcactgg actcagcttt tttctggttt
    14521 ttgatctgat ggattattta ggaaagagac atcttggaac agcaagtttt tttgcactac
    14581 ttatcgcatt tattttctat ctattagtaa aaagtataga caaacagacg agatttctca
    14641 acttgctttt tacttatcca actgaacact attttggagg tatttgtatt ttattaagct
    14701 ggggcgtgat ttacttggta ttgggaagtg ttcacttccg ctcatctaat tatctgcttc
    14761 tatctctttt gtcgatagtc atcagttttt tttctttgtt tttttccatt atgttgatca
    14821 gtttccaagt aaaagaaaga caacatcagg aatcgcttca actgtatcaa ataaatgaag
    14881 aatattacca tcatctagag gaattcaaac atgattataa aagtctactg ttttcattaa
    14941 aaattactct tcaggaaaat aaaaaagaaa cgttggaatt tttagaaata ttagaagatc
    15001 attctgcagc tatttttgaa aaaccgcaaa tacaacagct aacaaatatt gtatccccag
    15061 ctgtcagggg tgtcttttta aaatttctag aaaaagcaga atcggagaaa atcccgatcc
    15121 aagtagttat tcctgtcgaa gtgaaaacaa tcccgattga tctggttgtt tttattcgct
    15181 gtttatctat ttttatttct aacgcattcg atcatcgtgt agccgatcag agtccgatta
    15241 cgatcaatct gctggaagaa aaagagggat cacgttttag tatagcgaac aaggcaaatc
    15301 caacgaattt gacgctatcg gagatggtca aaagaggaaa aacctctaaa aaaaatggcg
    15361 ggttaggtct atacagtgcg aaaaaaatgt tggatgttta cgaaaatgca gaactaaaaa
    15421 tcgaattttc aaaacagaat cactattttt ttgtagaaat gtatctggca tctagaaaga
    15481 gcaaatcagc ctactgactt actgtcaaag gataagtttg aggaaagtct acacggagat
    15541 agagacaaca acacagcata ttcaaaagaa acagaagcgt gatgaccgtt gtcacccttc
    15601 tgtttctttt gctatgtagt taaacaaagt agttgacact tccgctactt agtattagta
    15661 cgaaagtata cttcatgata ctaagtagat aagaagtgaa aagcggaacc cacgatcgtc
    15721 aaaatgctaa ctgctttgct tacaccagat aaagggaaga gcaatatcgc ttattttagg
    15781 cgtggagaag caagcaaatc cctacgatca caaaaaaaat gctgacccag cagttaagag
    15841 agttagaaca agatgaaagt atccatcgaa aagcctataa ccaagtcccg cctaaagtag
    15901 agtactcgct caccgaagaa ggaaaatcat taagagagat tctagtagcg ttgtctgttt
    15961 gggaagaaga acgtatcgaa aaacaaaaag cctcaaggga agaagacacg ctactgcata
    16021 cacatggtgg ctacctaaat tattgatttt ctatgacatt tattttaaat aaaagaaaac
    16081 aggagttttt ttaaaagcat catctatttt ttatgtaaaa aaatggtatg attaatcaag
    16141 taagaagtga ttggaagaag gcaagcaaat gaatagtatg gaaaaagtca accagtttag
    16201 agatgaacgt aattggcgac aatttcataa cgaaaaagat ttggctatct ctatttcttt
    16261 ggaagcatct gaattgttag aactttttca atggaaaacg ccggaagaag taaaagaaac
    16321 acaattagaa cgaatcaaag aagaactggc agatgtattg atctattcat acatgatggc
    16381 agacaacctt cacctggatc tagatgagat cattgaagaa aaattgatca aaaataattt
    16441 gaaatatcct gtagaaaaaa gcgcaggtgt acgaaaaaaa tacacagagt tgtagaaatg
    16501 tgtcattcgg ctgttggaaa gagcaaaaga aaaacagtaa aatgagtctg gagggagaga
    16561 aaatgaaaaa aaaaggaaaa gcaaaaagat ggctagtcaa tatcctcttg ttcctcttgt
    16621 tattagtagg actagctttg attttcaatg aacagatcaa ggattatttt gtcagagaga
    16681 caggagataa atatgctata gcgaatgtaa caaaagaaga tctgaaaaag aataacgata
    16741 aagatgtcag ttttgacttt gatgcggtag aaccaatgac gacagaaggg gtcatgaggt
    16801 cgcaaatgag aggaacagat ctaccagtga ttgctagtat cgcagtccct tcagtttcaa
    16861 tcaatttacc ggttttcaaa ggcttggata atacgtcact actttacgga gcaggaacat
    16921 tatctccaga tcaagaaatg ggaaaaggaa attatgcctt agcaagccat cgtgcaacga
    16981 accctgaatt gctgtttaca ccgctagaaa atttagagat gggtgccaag atctatttga
    17041 cagatttaga aaatgtgtat acatacaaaa cattttttaa agaaaaagtt gctcctacag
    17101 atacccaatt actgaatgaa gtcgagggaa aagaaattgt cacactaatt acttgtggcg
    17161 acatggacgc cgtcacgcga ctagttgtac aaggagaact ggaaagtgtt acatcgataa
    17221 aagatgcgac agatgatatg agatctgctt tcaatctaga gacaaaaaca ttttaggata
    17281 ctgggacata agtcgttaca gattaaaaac agccaaagga tatgaatcga taaggaaaaa
    17341 ccaatttgct gaaaaaaaga gaaacgcaaa gaggtgcatc tctgatttgg ttgttttcta
    17401 gatagacttg tgttccagtt tttttatttt ttatatgaaa aggcttgcat aaataaaaat
    17461 tcgatggtat gatgattttg aataagaaat ggattgttac tgtacggcag gcaaaaccag
    17521 aattcagcta agaaacagta ggcgaattct aggttttttt atttttcttg agagggcgaa
    17581 gcaaaatgaa aattgataaa attttgaata acaatgtcgt catttcgaaa aatggattcg
    17641 gggaagaagt cgtttgtatg ggaaaaggac tagcttttca aaaaaagatt ggggacgaga
    17701 tttcgccaga agcggtccaa aaagaatttg tttaagagat tcttttgcta aaaaccaatt
    17761 ccagcagctg atggctgata ttccggcaga ggagatcgaa tgggtcaaac aagtagtcga
    17821 actggctgaa gataaactaa aagttgaatt ttcgcctaat atttatctga cattgaccga
    17881 tcatcttcat tatgcgatca cacgagcaaa agaaaatatc caactgccta atccattatt
    17941 atttgaaaca aaaaaatttt atccgaaaga atatcaagca gcgaaagagg ctcttttgtt
    18001 cgtgaaacaa aagacgggtg tggaactttc tgaggatgaa gccggtttta ttgcctttca
    18061 ttttgtgaat agccaacaag gaaacgaaga catgcaagtg acgatgaccg ctaccacaat
    18121 ggtaagagat atactgagta tcatcagtaa attcttcggc atcgtgttcg atgaagaatc
    18181 tttgaattat cagcgtatca ttactcatct gcagtttttt gcccagcgtt atctcaaagg
    18241 ggaaggatct gacgagcaag atgaatttct ctacgcatta gttcaaggaa agtatccaaa
    18301 agcgtttcat tgtgtcgaac ggatcaatga gtatcttcga caaacgcaaa aacaggaaat
    18361 ggggatcgca gagcagattt atttaacgat tcatattcaa agagtagtaa gtgagaaaaa
    18421 aagcatccaa tcataaggat tgttactgta tggcaggcaa aacctggatt gaaaaaatag
    18481 gttcacgaat gtttgtgact gtttttttca atctgggttt ttatttttta aataaaaaag
    18541 aaagaaggaa aaaacaatgg ataatcaagc agttggtcgt cgtgtatggg aagcggtagg
    18601 aggacaaaag aatgtcaaaa gtttagtaca ttgtgctacg cggttgcgat tcagattaaa
    18661 agatgaatct ttagcagata cgcaaaagtt aaaagaagac ccggacgtga tccaagtcgt
    18721 acaaagtggc ggtcagtatc aagtagtgat tggcagtaat gtagcagatg tttatcaatc
    18781 gatcgtggat gaggaaggtc ttgcagtttc ggaggatgga aaagaagagt ccaaaaatat
    18841 tttgaatcgt ctgatcgata ttatctctag tatatttaca ccttttctag gggcgatggc
    18901 agccgccggg gtattgaaag gattcttatc attggcaacg gtgatgggct ggctgacagc
    18961 tgatagcggt acttatcaaa tattgtttgc tgcagcagat ggtgtcttta ccttcttacc
    19021 tgtcatgctt gcttttacag cagctaaaaa gttcaaagcc aaccagtttt tagcagtagc
    19081 aattgctatg gcacttgtgt atccagctat cacagcagtt gctggtgcgg gagaagctat
    19141 cagtttcttt gggatcccag tgattctttc accatctggt tatacttctt ctgtcatacc
    19201 aatcattcta gccgtatggg ttcaaagtaa attagagcca ttcgtaaaaa aagtgattcc
    19261 gcaatttctg caaatgattt tagttccgct tgtcgtttta gtagtgatgg ttccattaac
    19321 atttcttgct ttaggaccaa tcgggacggt tgccggtaat gctttaggcg gtctcttcaa
    19381 ctcgatttat ggatttagtc caatcgtagc aggtctaatc atgggaagtt tatggcaagt
    19441 attcgtgatg ttcggcatgc attggggatt cgtaccgatc atgtttttga atatcgaaca
    19501 atatgggttt gatgtattga tgccaatgct tcttccagcc atcttggcac aaggtggggc
    19561 tgctttagct gtagcattgc gaacaaaaga tacgaaactt cgagcattag ggatttcttc
    19621 tacagtgact tcgttatttg gaatcactga accaactgtg tatggtgtga cattaccttt
    19681 gaagaaacca ttcattgccg cttgtatttc tggaggtatt ggtggagcta ttatcggatt
    19741 ttccggagta aaagctttct ccagcagttt ggtcagctta ttgacgattc cgactttcat
    19801 taatacggtg gatggtgtag agtcaaatgt gacagtagca gtaatagcta caggaattgc
    19861 ttttgttctt gcattcgtag gtacattgat tttaggattt gacgaacaaa cacaagacaa
    19921 tcaattagaa aacaaacatg cgaatgcagg agaaccgatt acttcagcac ggcatacctt
    19981 aaaaagtcct ttaacgggta aagtactgcc attgagtgaa gtaccagacc aagttttttc
    20041 ttctggcgtg atgggaaaag gtatcgctat tgatccagaa gtaggagaac tagttgcacc
    20101 tgcagacgga gagatcacga ctatttttcc aactggacat gctgtaggga tcacaacgac
    20161 tgacggagcg gagattttga ttcatatcgg gatggataca gtagaattaa atgggaatgg
    20221 ctttgagatc ttagtcaaac aaggggatct cgtcaaagca ggagatttat tgattcgttt
    20281 tgacatcgaa gcaattagag cagctggcta tagcgtaatc actccagttg tcattacgaa
    20341 tactgatgca tttgccgata tacttgaatt agaccaaaaa gagattattg caaacgaaga
    20401 tgttctggca attgtaaaat aaggaggaaa tcaggatgca atcacgtttt tcagaaaaat
    20461 ttttatgggg tggagcaact gctgccaaat caattagaag gggcttatga tcgagacgga
    20521 aaaggactat ccgttgcaga tgctatgcct ggaggtaagc agcgctttgc gattatcggc
    20581 agtgaagaat ttgactggac gattgatcaa gaaaaatata tttacccgaa tcatcgagga
    20641 atcgatcatt acgatcgttt caaagaagat cttgccttgt ttgcggaaat gggattcaaa
    20701 tgttatcgtt tttcgattgc ctggacacga atttttccaa atggagacga aggtactcct
    20761 aacgaagcgg gattagaatt ttatgatcag ctgattgatg agtgcttaaa atatgatatt
    20821 gaacctgtga tcacgatttc tcattacgaa atgcctcttc atttggcaaa agaatacggt
    20881 ggctggaaaa atcgaaaact gatcgacttc tatgaacgat ttgctcagac agtattagag
    20941 agatacagca gtaaagtcaa atattggatg actttcaatg aaatcaattc ggcctttcac
    21001 tttccagctt taagtcaagg attagtaaaa agcaatggag caggagagta ccaaaatatt
    21061 ttccaagcat ggcataatca attcgttgca agtagcaaag ccgtaaaaat cggccacgaa
    21121 ttgcgttcgg atatccaaat cggctgcatg attatctatg caacaactta cagcatcgat
    21181 gccaatccag tcaatcaggc agcaacaatg atccaaaacc aagaattcaa ttttttctgc
    21241 acggatgtcc aagtacgtgg agaataccct gcatacacag cgcgtaccca taaaaaatat
    21301 ggagtcgatc cggaaaaatt agagcaaacg gaaaaagact tccagttgct aaaagaatat
    21361 ccagtggact acatcggatt tagttattat atgtctacgg caatcaatga gactgatcca
    21421 caagcagcaa cttcagaagg gaacttgctg ggaggagtaa aaaatccgtt tcttgaggca
    21481 agtgaatggg gctggcagat cgatccagaa gggctgagaa tcgcattgaa tgaattatac
    21541 aatcgttacc agaaaccatt attcattgtt gaaaacggtc ttggagccat tgatcatatg
    21601 gaagaggatg gcacgattat tgatgattat cggatcgatt atttacgtcg tcatatcgaa
    21661 gcgatggcta atgcagtagc agacggtgta gatttgatgg gctatacgcc ttggggatgt
    21721 atcgatcttg tcagtgcatc aacaggagaa atgagtaaac gttacggctt tatctatgtg
    21781 gatctagacg atgaaggaaa tgggacactg aatcgatcaa agaaaaaatc ttttgattgg
    21841 tataaagaag taattgcctc aaatggcgta aacttgtaat taaagcagct gaatgaaaaa
    21901 gaacacactt ctcacatgtg atttgtgttc tttttttatt ttttatgtgc tattctttta
    21961 gtaatagtaa agcaaagggt gacgttatga aaaggacacg tgtactatac ttggaagtcg
    22021 cagataaaat taaagaagat attttctcag gaaaatatcc agtcggttcg atgttgccga
    22081 cagaaagtga attagaagaa ctgtttcaag tcagcaaaat cactgtccga aaggcaatcg
    22141 aactgctggc atcagatgaa tatgtcgcaa agaaaagtgg tcgtgggacg acggttctaa
    22201 gcaatcgtcc ttacaatcga ttatccaaag cggcaagctt tacgcaaatc ttggagaact
    22261 cccgatatga agtccggaaa gaaacgctgg atttgcaatt ggtccatata aagaaggaag
    22321 atcctttgtt ttcctttttc ggtgagcaag ctgtttgttt taagcgctta tattatttga
    22381 acaatcagcc ttatatttat tttgttcatt atcttccaca agaaatgatg caattcagca
    22441 gagaagaatt tggcaaagaa tctttgtatc gtttgctgac gaaaaaagga tatactattg
    22501 actcattttc tgatgatttc tcggcagtat ttttaacaga agaagaacaa ggaattctga
    22561 aaacagacgc acagatcggc atcaaacgga tacggaaatc gtctacgcaa attggggaaa
    22621 tgattgaata ttcggaggcg gtctaccata cggagctgca tccttaccat attgattatg
    22681 aaacataaat aaaaaaagag gttgtgaaaa agctgccctg catcaagtaa taagaacagc
    22741 caaacaaaaa tagcttctca tatttttcgt ttggttaggc ttattaccgc agatacacgg
    22801 ctgtttctgg attaccattt attctggata agggggtgtg gcacgatttt cagaaggaat
    22861 ctatgaacca atcactgtat tgattttagc ttcgatggta accccattcg gcttgacgat
    22921 cgcttatttc ttagggaaaa tcattcgtaa aaatatactc aatcgtcaag aaatcgatac
    22981 attgaagacc gcttttccta tggggatctg tcagatcaca gagggatgtt tccctatcgt
    23041 attgaacgac ttggcacgca atgtcatagc aacgggagtc ggtgggacag taggtggcgg
    23101 attaagcatg ttttggggcg cagatagccg tattccggca tcgggaatgt ttgcagtcgc
    23161 tacgatgacc agaccatggg cattcattgg tgcattgtta gctggttctt ttgtcacagg
    23221 aataaccatt ttattattga aaaaaccagt agatccgaat gcagaaatca tccaagaaga
    23281 aaaagaggaa gaagacatat cttgggatga tttgacaatt agttaggaga ggcagaatgg
    23341 attacaagaa aaaagtacaa tagatgtacc ttgagacagg aatggtatga aagaatcaga
    23401 gttagaaaga atcgaatata cagattttgg tttaggagcg atcgaaactg tccagagcat
    23461 cggcaccctc cttgaaatga cgatgaagga aaaatgagaa cctttcgttg tcgaaagggt
    23521 ctggtatacc ttatgtcgaa ggaaaggaaa caaaaaaact ttcctgtact attccaaaaa
    23581 ggaaagaaag ttattataca gtaaaaaaag aaattattct tcatgctaga gatcagtaca
    23641 cgttcgagcc caatatcaaa cactagttcc aggcaggcgc aacaggtgcg gttatcactg
    23701 aattttcttc cagcagtgac gattcaagtg atatttttac aaatccagct atttatcgtt
    23761 aacaaaaaga tttttaggag aagctgatga acaaaaatga tcaaattttg atcgtttagt
    23821 tcgtcggctt ttttatttag agaaacatca tttatcagtg aaacataaca cgagaacaaa
    23881 atgatttttt cgttaataaa agaaacaagt atttgttgtt taaaataata cacgttattg
    23941 gcatatagga cgaaatccca gtatcttcta taagtaagtc atttcatatc gatgaaaaca
    24001 c
//
LOCUS       DAFLVO010000040        23828 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.040, whole genome shotgun sequence.
ACCESSION   DAFLVO010000040 DAFLVO010000000
VERSION     DAFLVO010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23828
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.040"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(53..787)
                     /locus_tag="L1U99_001679"
     CDS             complement(53..787)
                     /locus_tag="L1U99_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBN1212221.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="L1U99_001680"
     CDS             1114..1524
                     /locus_tag="L1U99_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBN1212222.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="L1U99_001681"
     CDS             1517..2218
                     /locus_tag="L1U99_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBN1212223.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="L1U99_001682"
     CDS             2218..3804
                     /locus_tag="L1U99_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1212224.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="L1U99_001683"
     CDS             3823..4044
                     /locus_tag="L1U99_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HBN1212225.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="L1U99_001684"
     CDS             4041..4802
                     /locus_tag="L1U99_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HBN1212226.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="L1U99_001685"
     CDS             5182..5691
                     /locus_tag="L1U99_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBN1212227.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="L1U99_001686"
     CDS             complement(5766..6305)
                     /locus_tag="L1U99_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBN1212228.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="L1U99_001687"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="L1U99_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBN1212229.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="L1U99_001688"
     CDS             7318..8169
                     /locus_tag="L1U99_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBN1212230.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="L1U99_001689"
     CDS             8197..8832
                     /locus_tag="L1U99_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBN1212231.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="L1U99_001690"
     CDS             8852..9625
                     /locus_tag="L1U99_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1212232.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="L1U99_001691"
     CDS             10033..10830
                     /locus_tag="L1U99_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HBN1212233.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="L1U99_001692"
     CDS             10808..11221
                     /locus_tag="L1U99_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBN1212234.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="L1U99_001693"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="L1U99_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBN1212235.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="L1U99_001694"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="L1U99_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBN1212236.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /gene="maf"
                     /locus_tag="L1U99_001695"
     CDS             15998..16558
                     /gene="maf"
                     /locus_tag="L1U99_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBN1212237.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="L1U99_001696"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="L1U99_001696"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HBN1212238.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="L1U99_001697"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="L1U99_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HBN1212239.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="L1U99_001698"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="L1U99_001698"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HBN1212240.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="L1U99_001699"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="L1U99_001699"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBN1212241.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="L1U99_001700"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="L1U99_001700"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBN1212242.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="L1U99_001701"
     CDS             21905..22483
                     /locus_tag="L1U99_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1212243.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="L1U99_001702"
     CDS             22535..23017
                     /locus_tag="L1U99_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HBN1212244.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="L1U99_001703"
     CDS             23134..23508
                     /locus_tag="L1U99_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212245.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7781 a         4286 c         5115 g         6646 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaca
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcaccgggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaacaa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcatagcatg acagcattcg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ttagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagttt
//
LOCUS       DAFLVO010000041        23653 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.041, whole genome shotgun sequence.
ACCESSION   DAFLVO010000041 DAFLVO010000000
VERSION     DAFLVO010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23653
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.041"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(26..601)
                     /locus_tag="L1U99_001704"
     CDS             complement(26..601)
                     /locus_tag="L1U99_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBN1212246.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(606..1580)
                     /locus_tag="L1U99_001705"
     CDS             complement(606..1580)
                     /locus_tag="L1U99_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleosidase"
                     /protein_id="HBN1212247.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(1604..1648)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1863..2831
                     /locus_tag="L1U99_001706"
     CDS             1863..2831
                     /locus_tag="L1U99_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1212248.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            2928..3221
                     /locus_tag="L1U99_001707"
     CDS             2928..3221
                     /locus_tag="L1U99_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBN1212249.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIVDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            3339..3575
                     /gene="secG"
                     /locus_tag="L1U99_001708"
     CDS             3339..3575
                     /gene="secG"
                     /locus_tag="L1U99_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBN1212250.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3678..4433
                     /locus_tag="L1U99_001709"
     CDS             3678..4433
                     /locus_tag="L1U99_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBN1212251.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            4436..6793
                     /gene="rnr"
                     /locus_tag="L1U99_001710"
     CDS             4436..6793
                     /gene="rnr"
                     /locus_tag="L1U99_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBN1212252.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            6815..7279
                     /gene="smpB"
                     /locus_tag="L1U99_001711"
     CDS             6815..7279
                     /gene="smpB"
                     /locus_tag="L1U99_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBN1212253.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            7581..8300
                     /gene="atpB"
                     /locus_tag="L1U99_001712"
     CDS             7581..8300
                     /gene="atpB"
                     /locus_tag="L1U99_001712"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBN1212254.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            8353..8568
                     /gene="atpE"
                     /locus_tag="L1U99_001713"
     CDS             8353..8568
                     /gene="atpE"
                     /locus_tag="L1U99_001713"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBN1212255.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            8659..9183
                     /gene="atpF"
                     /locus_tag="L1U99_001714"
     CDS             8659..9183
                     /gene="atpF"
                     /locus_tag="L1U99_001714"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBN1212256.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            9170..9712
                     /locus_tag="L1U99_001715"
     CDS             9170..9712
                     /locus_tag="L1U99_001715"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBN1212257.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9735..11291
                     /locus_tag="L1U99_001716"
     CDS             9735..11291
                     /locus_tag="L1U99_001716"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBN1212258.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            11305..12207
                     /locus_tag="L1U99_001717"
     CDS             11305..12207
                     /locus_tag="L1U99_001717"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HBN1212259.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            12230..13636
                     /gene="atpD"
                     /locus_tag="L1U99_001718"
     CDS             12230..13636
                     /gene="atpD"
                     /locus_tag="L1U99_001718"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBN1212260.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            13650..14072
                     /locus_tag="L1U99_001719"
     CDS             13650..14072
                     /locus_tag="L1U99_001719"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HBN1212261.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            14541..14771
                     /locus_tag="L1U99_001720"
     CDS             14541..14771
                     /locus_tag="L1U99_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HBN1212262.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            14868..16169
                     /gene="murA"
                     /locus_tag="L1U99_001721"
     CDS             14868..16169
                     /gene="murA"
                     /locus_tag="L1U99_001721"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBN1212263.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            16182..16358
                     /locus_tag="L1U99_001722"
     CDS             16182..16358
                     /locus_tag="L1U99_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBN1212264.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            16493..16789
                     /gene="yidD"
                     /locus_tag="L1U99_001723"
     CDS             16493..16789
                     /gene="yidD"
                     /locus_tag="L1U99_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBN1212265.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            16853..17320
                     /locus_tag="L1U99_001724"
     CDS             16853..17320
                     /locus_tag="L1U99_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1212266.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            17405..18289
                     /locus_tag="L1U99_001725"
     CDS             17405..18289
                     /locus_tag="L1U99_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1212267.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLIGAAANYLAVRQGEN"
     gene            18403..18639
                     /locus_tag="L1U99_001726"
     CDS             18403..18639
                     /locus_tag="L1U99_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HBN1212268.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            18727..18807
                     /locus_tag="L1U99_001727"
     tRNA            18727..18807
                     /locus_tag="L1U99_001727"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18761..18763,aa:Tyr,seq:gta)
     gene            18814..18885
                     /locus_tag="L1U99_001728"
     tRNA            18814..18885
                     /locus_tag="L1U99_001728"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18846..18848,aa:Gln,seq:ttg)
     gene            19011..19181
                     /locus_tag="L1U99_001729"
     CDS             19011..19181
                     /locus_tag="L1U99_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212269.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            19401..20108
                     /locus_tag="L1U99_001730"
     CDS             19401..20108
                     /locus_tag="L1U99_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1212270.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRRDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(20167..20811)
                     /locus_tag="L1U99_001731"
     CDS             complement(20167..20811)
                     /locus_tag="L1U99_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBN1212271.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKNFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSANHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            20938..21225
                     /locus_tag="L1U99_001732"
     CDS             20938..21225
                     /locus_tag="L1U99_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212272.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            21333..21653
                     /locus_tag="L1U99_001733"
     CDS             21333..21653
                     /locus_tag="L1U99_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1212273.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIA
                     LIGE"
     gene            21971..23047
                     /locus_tag="L1U99_001734"
     CDS             21971..23047
                     /locus_tag="L1U99_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBN1212274.1"
                     /translation="MFDQPEAKPREVVFFWTGQLTEKQTEIAKRILCHSEKRHHLIWA
                     VTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNELFLRYRYVFPEEKITLLHGNTA
                     TAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYNGDAGLAHAVQTAIRSNGRFIY
                     LSATPDEKLLKEIKQTFELHKLALRFHRRLLPEPVLVFMNNWRQKCGNKKKINSLVRI
                     IQQLIKENRILLFCPSITMMHRLKITLQEAFPEYEITDVSSQDDQRAKKVQKMREAIY
                     EILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQIAGRADRKGPYTNSRVYFFYE
                     EKTSAIRKACQEIKEMNEEGKQML"
     gene            23044..23653
                     /locus_tag="L1U99_001735"
                     /pseudo
     CDS             23044..23653
                     /locus_tag="L1U99_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
BASE COUNT         7820 a         4125 c         5092 g         6616 t
ORIGIN      
        1 attttgctaa tccagctctg tttattcagc ctatttttct ttttgaatat atcaagcgtt
       61 gtggcaacat agtgatgact aatgaaacaa cgacgataga caacaaacga tcaaggtagt
      121 ctgtacctgc ctgtaccaag atcacacttg ttgtctgact taaacctaac ccatgtaata
      181 gctgaacgat catactggat cctgaggagg tgatcccgcc aaataactga acggtaatga
      241 tcgaagaaac gatcgttcca ggtaccgaca aaatcaaagc gagtaataac agtttcaagc
      301 tgtttttatc tttgccgaga tatcttggca aaatcaatcc agcaagcaag cctgtgagaa
      361 tttggattgg cgaataatac agagaaaaaa tatctgtagt cactccactt aaaataccgc
      421 tggacaatcc tgtcagcatt ccaggtacag gcccaagcaa tgcaccagca aaaatcgttc
      481 cgatagaatc gagatagatt ggcaaacgaa gccataaagc aatcgttcct ccaatataat
      541 tgatcccaat acacaaagcc atcactgtaa gtacgcgagt tgccattttg tttttattca
      601 ttttgttagc ccatctttaa cctttccaaa tctttcataa tcgtttcttc ttgtgcattt
      661 aaaagaacgg ttaaaaactt tcggaaaaaa agacgagtat ctacttttgt cataatttta
      721 ctgttagcag gtttctgcca aaattcataa cgatcaacca atgtttgtcc acgacttatt
      781 ccttgagttt ccacagcagt gaagcttttg aaaccttcac agatggcctc ctcgataaaa
      841 taagcaacag ctaacggatc attgatgaca catcctaaaa ttctttcttg tttccagtgg
      901 aagtcaaaat aaaaacgagt gatcgctttt agatactctc cctcttcagg attcatttga
      961 cagcagtatt cgaggatagt cggtgtcaag acgatttctc ttgtcacatc taacccaacc
     1021 atttctatcg tttgtttgag attctcgaat acataagaag ctgcttcagg atcacaccag
     1081 taattgtatt cagcaactgg cgaacagtta ccatggcttt tgtaagttcc acccatcgag
     1141 acaaaacgtt ccatatgttt cccaatattt gggttgactt tcaaagcaga agcgatattg
     1201 gtcaaaggac ccaaagcaat gactgatgta tttgtctttt ctttgaaata atcagccaaa
     1261 aaatcaacgg catggagagg ttctgcctgt tttctcaaga tcatcgggaa atttgtttcc
     1321 cctaaaccat ccataccatg agtgtcttgt gcactgatga aaggttgctt caaaggtttt
     1381 tccattcctt gataaacagg aatgtctaaa cgatcacagc gttccaggca tttcagcaca
     1441 ttctgcgtac ctatatctgc agggacattc ccacaaacta cggtaatagc aactacttcg
     1501 atatcagggg atttgacagc taatgataaa gctaaagtgt cgtcgatccc tggatcgcaa
     1561 tcaataatta cttttcgcat tatttccaat ctcctttctt tagagatact tagtttttta
     1621 ttctgggaag tttccgaacc agtccaagac gagcgtcttg attataatgc acgaaattag
     1681 tatactggct tttattgcga atgtaaatgc tctcttacaa gtaaatctat tgaggagaac
     1741 tttaagtaaa tgatacaatg aaaaagaaat ggaatttacg tgtgccgaaa ataaagaatc
     1801 ctatggatcg gtacattgga taatagatag attatagttt ggcagaaagc ggcgggtgta
     1861 caatggttat tttttatttc attcttattc tgataattat agggatcagt taccattttc
     1921 tttcttattt ttatgcaaag aaattagtaa gagcgggagt acagagagga tatgactggt
     1981 atgaagacac tggtcatcgt ttgatggacc ctgctgcagt cacgtcagta gaaaaaaaac
     2041 gacaaaaatt agaagaagag tgtgaaagct tttgggagca gggaacaccc aaaacaatca
     2101 aaagttatga cgggttgaaa ctagctggtc agatgttcat ccatccaaat aagcagaata
     2161 aatgggtcat ttgcgtacat gattaccgaa gcacagggaa aagagacatg tctcatatag
     2221 gtaaaagata tgcagagaaa ggattcaacg ttcttgtacc tgatttacgt gcgcacggag
     2281 aaagtgaagg agaaatcatc ggaatgggat ggctagatcg gctagattta attgcctgga
     2341 tccaactcat cttagatgaa cagccgaatg cgtccattat tttacacggc ggatcaatgg
     2401 gagcttctac gatcatgatg gcaagtggtg aaaaacttcc atcagcggtc aaaggattta
     2461 ttttagacag cggatatgtt tctgtttatg cagaattccg atatatgtta agtaaaatca
     2521 ctgtctttcc taaaaaaatg gtcatgagat atgcgaatca ttatgcccag aaatacgccg
     2581 gttactcctt aaagcaagca tcagctacga gacagcttgg cagcaatcat ctgcctttat
     2641 tagtcatcca tggtgaaaga gatcattttg tccctacaga agcagcgtac acgattcaaa
     2701 atgctacggc aggggataaa gcactgctgc ttgttccgga agcagaacac ttggaagcat
     2761 cgatgaaaga tccgaaaacc tattggacag tgattttttc atttattgaa caaagaataa
     2821 cgatgaatta attttctctt cttttttgta agtaattcga ggataaataa ttgtttatag
     2881 atcaggagac tgctaaaata aggtaggaat aaaaaaatat cagttatttg aggagtgcgg
     2941 catatggaaa tcaaagaaga aaaaatcgtc ttgctttatt caatgatgaa caacaagaga
     3001 tcggagaaat gacatggtca gatgcgggcc cagacatcat gatcgttgac catacatttg
     3061 tagatccagc atatcgtggt caaaagttag ctgaaaagct agtgtatact ggagtagaat
     3121 tagcaagacg agacgggaaa aagatcattc ctttatgccc ttatgcaaaa aaagagtttg
     3181 aaaagaaacc agaatatcaa gacgtcttac gtcagtcata agaataacag ctgaaagttt
     3241 tgaactttca gctgttattc catttatata gagttgtcac ggacttttat ctatgataaa
     3301 gttaaagaga cgatatcttt tgggaaggag gctgcgatat gtataattta attttgggaa
     3361 tcgtgatcgt tttatcgatt gttatggtca ttgcgattat gatgcagcca agcaagcaaa
     3421 atagtgcagc gagtgcattt accggcggtg cggatcaact attcggcaaa caaaaagctc
     3481 gcggctttga agctgtcatg cagcgatcaa ctgcagttat gggagctatc tggatgatct
     3541 tattatttgt cctagcatat ttatcttcga agtagttgaa taagcctctc gcaaaacggc
     3601 gggcggcttt ttttattgca aagagaacgc ttaagaagaa gttatgaaag aaactatggt
     3661 aaaatgaggc gaaagaggtg agacgagtga gacaattacc aaaacccctt tatgcaaaac
     3721 atggaaagcg agcggttttg ctgcttcacg cttactcagg aagtccaaac gatgttcgaa
     3781 tgctcgcacg atttttggaa aaagcagatt atacagttta tgcgccgctt tttaaaggac
     3841 acggaacaat ggagccatat gatatcttgc aagaaaaagc agaaagctgg tgggcagaca
     3901 ctaaaaaagc catccatttt ttacagtctg agcagttttc tgatattgcc gtattaggat
     3961 tatcaatggg cggcatcttt gctgtacgag cactagaaga agaatcagtg attggcggcg
     4021 gttttttctg ttcgcctttg tctcctgtaa aaacaaacgt gcctgaaaac tttgaaaaat
     4081 acgtacgtca agtgctgaag acagcaggta aatcagagaa agaaatcaat gaaaaagcag
     4141 ttgcttaccg ctcgttagct gaacaacaat taatggatat acaagatcag gcagcaatcg
     4201 tagaaagtag gttgtcagat atccaacagc cgatattttt agctcaagct gggaaagatg
     4261 aaatgatcga ccctaatggc gtatttgaaa ctgcacgcaa gttgagccgt cagcgagtga
     4321 cacttcaatg gtatcctgaa agtggtcatg tgattacagt tggtacagca agacgcgaat
     4381 tagaaaaaga cgtcttggaa tttttagaaa aattaccttg gaatgaggaa taaatatgac
     4441 aaaagaaacg ataaaagaga aaattctctt tttcatggaa agcagtcgca aacgcagttt
     4501 ttctatggaa gaaatcgctg aaggtttagg gttccaaaaa agcgatgatt ttaaattact
     4561 agtacaaacg attgctcaaa tggaaagaga acagagtata gttttcaata aaaaaggaaa
     4621 agtgaaactt cctttaaaac caatcctgat cgaaggaaca tttcgagcaa atgaacgagg
     4681 atttggattt gtaacgattg atcccgaaga agatgacatc tatatcccaa aagaagcgac
     4741 tggttttgca atggatggag acaccgtagc aatcgatatc atgaagcgag caaatacaga
     4801 tatggatcgc ggagcagagg ggaaagtagt cgagattcga gaccgggcga ctactcagtt
     4861 agcaggggaa ttcgttgctt attcagaaga agaaatacaa gaaacagatc tttacggcgt
     4921 tgttatcccg aaagatagaa agctcaacca atttaaagta tatgcagcag cagagggagt
     4981 tcgtccagtt gacggaagta ttgtgctgat cgaactgacc cattaccctg aaaaagggta
     5041 tgcgactagt ttagaaggga taatcaagca agtgattggt cataagaatg accctggcat
     5101 ggatatcctc tcaattgtcg tggctaatgg tatccctacg aaatttcctg atgatgtatt
     5161 gtctgaagca gatgaagttc cagatcaaat cagcgaaaag gatataactg gacgtagaga
     5221 tttaagaaat cagctcattg ttacgattga tggagaagat gcaaaagatc tagatgatgc
     5281 agttacggtt aaaaaattag ataacggtaa ttattttctt ggagtacaca ttgcagatgt
     5341 ttcttactat gtgacacaag gcagtcaatt ggacagagaa gcatatgaaa gagggacaag
     5401 tgtatatttg actgatcgag taattccgat gatcccgcaa cgtttatcga atggtatctg
     5461 ttcactgaat ccccatgttc caaggctgac catgagttgc gaaatggaga ttgatccaaa
     5521 tggacaagta gtctctcatg atattttccc aagtgtgatc caaacaacag aacggatgac
     5581 ctacacagct gtcaatcaaa tcttagaaga tcaagacgaa gaaacgatgc aacgctatgc
     5641 tcagctcgta cctatgttcc aagaaatggg tgaattgcac cgaatccttg aaacgatgcg
     5701 aatcaaacgt ggcgcgattt cttttgagga tcgcgaagcg aaaatccttg ttgatgctga
     5761 aggacaccca aatgacatcc agctaagaag cagaggaatt ggtgaacgct tgatcgaatc
     5821 tttcatgctt gcggccaatg aaacggtagc tgaacattat aataaattaa atctgccgtt
     5881 tatttaccga atccatgaac agccaaaaga agaaaaaatg cagcgcttct ttgattttgc
     5941 ttcagctttg ggcattctgg tccgaggaac gaaaggaacg atcacaccaa aagatttaca
     6001 gcatgtgatc gaaggagtag aagacaaacc agaagctgca gttatcaata ctatgttgct
     6061 aagaagcatg caacaagcac gctattcaga agacaatttt gggcattatg gcttagcggc
     6121 agattactac acacacttta catctcctat tcgacgctat cccgatctaa tcgtccatcg
     6181 tctgatccgt tcttacagtg aagataaaag tgaaagcaat caaagttcgt gggctgcgga
     6241 acttcctgaa attgcagatc atagttctaa gatggaacgt cgtgcagtag aaacagaacg
     6301 tgaagtagat tccatgaaga aagcagaatt catgatggac aaagtgggag aagaattcga
     6361 tgggatcatc agctctgttg tgaaattcgg cctgtttatc gaactgccga atacagtaga
     6421 gggattgatc catatcaatg aattgaaaca ggactacttc cattttgttg aaaatcattt
     6481 agctcttgta ggtgaaagaa ctggtctgac ttttaaaatc ggacagaaag tgcgagtaaa
     6541 agtagtcaaa gctgatccag atgaacgagc agtagatttt gaacttgttt ccgcagaaga
     6601 ggttacagcg ttggaacggc caaaaacacg aaatggaaaa tcaggaaaac gcgaaggaaa
     6661 acaagcagga aaacgcccag aaagaaatgg caagaagaac aaacgatata gcgatagtaa
     6721 gcaaacgttc ggtaagaaaa aagggaagaa gccattttac aaaggtgtta aaaagaagaa
     6781 aaagaaaaaa taaaatgagt tggaggaaac agctatgcca aaaggcgagg gaaaattaat
     6841 tgcacaaaac aagaaagctc gccatgatta ttcgatcatc gacacgatgg aagcagggat
     6901 ggtcttgcaa ggaaccgaga tcaagtcgat acgaaacagc cggatcaatc taaaagatgg
     6961 atttattcgc gtccgcaacg gagaagcttt cttgcataat gttcatatca gtccttatga
     7021 acaaggaaat atttttaatc atgatccgtt gcgcacgaga aagttattat tacacaaaaa
     7081 acaaatcatc cggcttgaaa atgaattgaa aaatactgga atcactgttg ttcctttaaa
     7141 agtctatatt cgtaacggct atgccaaggt attgattggt ctggcgaaag ggaaaaaatc
     7201 ttatgataaa cgggaagatt tgaaacgaaa agatatcgat cgacaaattg atcgaacatt
     7261 aaaaaatttc tctagataat ttcattatcc tttttcgcat attcggtgct tttgctttta
     7321 cttaatgata aaatttgtta gcatttaatc tgataaaaca tgattatcat aggttttttc
     7381 ttagatcagg agcaccgtgt ataaagaaaa attcgcttcg tttttgactg aaataaaaaa
     7441 gtgtctaatt ttcatgaaaa tgttttgaat tttctgtttc atggtggtat gataccgtgt
     7501 ggttagaaac cgattggaaa aaaccagata cgcacatgaa ttgattttat gtgaatttcg
     7561 gggaaaagag gtgaaatgga ttggatgaac gctcgctaac gttccacatt ggaccaattt
     7621 ggtttgatgg tacagtttgt ataatggtgt tactgacctg tttgattgtt ttcttcttag
     7681 cttacttttt tacaagaaat cttaagttga aaccaacagg caaacaaaat gcgatagaat
     7741 gggtcattga ttttagtcga ggaatcgtaa cagataatct gcctagaaaa gaattgagca
     7801 atttccattt gttggcattt acattgtttt tatttgtttt tgttgcaaac aacatcggtt
     7861 tagtaacaaa aatcgtttta cctaacgaaa caacactttg gaaaagcccg acagcagacc
     7921 cgtttgttac tttaactttg gcatttataa tgatcttact tactcactta ttcggggtga
     7981 aaaagttagg cttcaaagga tatttcgtaa attcgttctt gaaaccctat agttttatgt
     8041 ttccgatgaa actgattgaa gaatttacaa acttattaac acttgcttta cgtctttatg
     8101 ggaatattta tgcgggggaa gttttgctaa ccttgattgc aaaaatgatg acaagcttag
     8161 gctggttctc attaccatta gcaattccat tagagatggt ctggatcgcg ttctccttgt
     8221 ttattgggag catccaagca tttgtctttg tcactttgtc aatggtttat atgagccata
     8281 agattgaagt agaagaataa tactcggtta aaaaacaaac tactatttat ctattttagg
     8341 aggaaaacaa ttatgaatta tatcgcagca gcaatcgcaa tcatgggagc agcaatcgga
     8401 gccggttatg gtaacggtca agttatctct aaaacaatcg aatcaatggc tcgccaacct
     8461 gaaatgtctg gtcaattccg tacaacaatg tttatcgggg tagctctagt tgaagctgtt
     8521 cctatcttag gggtagttat cgccttgatt ctagtttttg ccgtttaatt gaatcagtat
     8581 taaggcagaa acaacatcgt ttgttactgc ttttttacat ggaaactaga aatactccaa
     8641 agaaaggaag gctcgcctat gctgaatcaa ttggcaattg cagaagttgg caatgcgatg
     8701 ttaggtaata tcatcgttgt cagcggctca tttttgatac tactggctct cttgaagcac
     8761 tttgcttggg gaccaatcag cgatattttg aaaaaacgtg aagacaagat cgccaatgat
     8821 ttagattctg cagaacaatc tcgcatcaac tcagcgaaaa tggaacaaga acgcgaacaa
     8881 caattgttag cctctcgttc tgatgcagct gatatcatca aaaatgcgaa agaaagtgga
     8941 gaattaagcc gccaaaatat tttgaaggat gctcaagaag aagcagctcg tctaaaaagc
     9001 aaagcccaag ctgatatcac tgtagaacgt gattcagcgc tgaactctgt aaaagacgac
     9061 gttgcagaac tctctcttca aatcgcggaa aaaatcttga acaaagaatt atctccagaa
     9121 atgcatgaat cattaatcaa tcaatacatt gaaggtctag gttcttcaaa tgaaactaga
     9181 taaatataca gtaggaagac gttacgggaa agctttattt gaactggcga tcgattcaaa
     9241 tcaagcagaa gaaatctatc aagatctcgt aagtttacgt caaatctatg aacaagtacc
     9301 tggattaggg aatatgttaa gtgatgttcg tctagaacct catgaaaaac gagaaatcat
     9361 ggacaagctt gtcagcggtt atgatgggat cgttaaaaac tttttagaag ttgtttatga
     9421 gtataaccga atggatgacc ttttgttcat gatcgaagaa tatgaacgtc gatatgatga
     9481 acatcaaggg ttactattgg gaagtgtcac aacagcagtc ccactttcag acgaacaacg
     9541 aatacaatta gaaaagaatg ttgcaaaaac aatggactat caatcagttg aattaaaaca
     9601 aatcgttgat tcttctatta ttggtggcgc gattgttgaa gccaaccatc gagtaatcga
     9661 cggaagcatt cgcacgcaat tagaaaaaat gcgtaatcaa ttaaacagat agtacaaaga
     9721 ggtaggtgaa tcgaatggcc atcaaagcag aagaaattag tgccttgatt aaagaacaaa
     9781 ttgaaaatta tcaaaacgtg ctttcagtcg aagaaatcgg taccgtaact tatgtaggtg
     9841 acgggatcgc tcgtgcacat ggtttagaaa acgcgatgag tggtgagttg cttgaatttt
     9901 caaacggctc atacggaatg gcgcaaaact tagagtcaaa tgatgtaggt atcattatcc
     9961 ttggcgattt cgagtccatt cgtgaaggag ataaagtaaa acgaacaggt aagatcatgg
    10021 aagttccagt tggagaggcc ttgatcggtc gggtagtcaa tccgctaggt caaccaatcg
    10081 acggactagg tgaaatcgtt actgacaaag ctcgtccagt agaagcgatg gcaccaggtg
    10141 ttatgcaacg taaatctgtt aacgaaccaa tgcaaacagg gctaaaagcg atcgacgccc
    10201 ttgtgccaat cggacgcgga caacgtgaat tagtcatcgg tgaccgtaaa acagggaaaa
    10261 cttctattgc gatcgatacg atcatcaacc aaaaaggtca agatatgatc tgtatctatg
    10321 tagcaatcgg acaaaaagat tctacagttc gtacacaagt tgaaacattg aaaaaatatg
    10381 gcgcaatgga ttacacaatc gttgtgaatg ccggtgcgtc tcaaccagca ccattgcttt
    10441 atatcgcacc atatgctggt actgcaatgg gtgaagaatt catgtacaac ggtaaacatg
    10501 tattgatcat ttttgatgat ctttcaaaac aagctgttgc ttatcgtgaa ctttccttgc
    10561 tacttcgccg tccaccaggt cgtgaagctt atcctgggga tgttttctac ttgcactcac
    10621 gtttattaga acgtgcagca aaattaagtg atgatttagg tggcggttca atgactgcct
    10681 taccatttgt tgaaacacaa gctggagata tctctgctta tatcccaaca aacgttattt
    10741 cgatcactga tggacaaatc ttcttagaaa gcgacttgtt ctacgcaggt actcgtccag
    10801 cggttgatgc cggactatct gtatctcgtg taggaggttc tgcgcaaatc aaagcaatga
    10861 aaaaagttgc tgggacttta cgcctagact tagcaagtta ccgtgaatta gaagcattta
    10921 cacaattcgg ttctgacttg gatgcagcaa cacaagcaaa actaaatcgt ggacgccgta
    10981 cagtagaaat cttgaaacaa aaattgcatg caccgctagc tgttgaaaaa caagtagtga
    11041 ttttgtatgc tttgacacat ggattcttag atagtatccc tgtagacagt attttagact
    11101 tcgaacatga attattcgaa tatctggata ccaatcattc agatatcttt gaaacaatcc
    11161 gtacaacaaa agatcttcca gaagaagaag cgttgaacag tgcgattcag gaatataaag
    11221 acatgttctt agctacaaaa ggaagtaatt cctctacaga agataaattg aaatccattc
    11281 aaaatgcata gtgaggtgag atgaatgggt gcttcattaa atgaaatcaa gacacgtatc
    11341 gcttcaacga aaaaaacgag ccaaatcacg cgggcaatgc agatggtgtc tgcttctaag
    11401 ttgacaaaat ctgaagcttc ttcacagaag tttcaggttt atgcaacaaa agtaagagaa
    11461 atcgttacgc atttgactgc tactcagtta aatgatattg cctcagaaaa tcctagaggg
    11521 gatatcaatt acaacagcat gctgctcagc cgtcctgtga agaaaactgg ttatatcgtc
    11581 atcactgcag atggcggttt agtcggtgga tataacagct cgatattgaa acaaacgatg
    11641 tctattttag aagaagacca ccaatcaccc gatgattacg tgatgatcgc aattggcgga
    11701 actggtgcag acttctttaa agcacgcggt atcaatctag catatgagct gcgcaatcta
    11761 tctgatcagc caagctttga tgaagtccgc aaaattgtaa atatggcaac aactatgttc
    11821 caaaacgaag tattcgatga attatacgta tgttataacc atcatatcaa ttcgctaact
    11881 agtcagtttc gtgtagaaaa aatgctgcca atctcagact tagatccaga agaagcaacg
    11941 actttcgaac aagaatatat ttttgaacct tcaaaagaag aaatcttgtc tcagttattg
    12001 cctcagtatg ctgaaagttt gatctacggt gcgatcgttg acgccaaaac agcagaacat
    12061 gctgctggta tgacagcaat gaaaacagca actgataatg ctgctaatat cattgatgag
    12121 ctgacggttt cttataaccg tgcaagacaa ggggctatta cccaagaaat taccgaaatt
    12181 gttgccggag cttcggcact agaatagtat tgagattgga ggaaaaaaga tgagttcagg
    12241 caagattgtt caagtaatcg gtcccgttgt cgacgtggaa ttttctttag accaatcctt
    12301 accagatatc aacaacgcat tagttgttta taaaaatgac gaaaataaat caaaagttgt
    12361 tcttgaagca gcgttagaat taggggacgg agtgatccgg accattgcga tggaatcaac
    12421 agatggttta caaagaggaa tggaagtcat tgatacaggc aaagcaatct ctgttcctgt
    12481 aggtaaagaa acattaggtc gcgtattcaa cgtactagga gatacgatcg atttagaaac
    12541 acctttccca gaagatgcgg aaagaagcga aattcataaa aaagcaccag cctttgacga
    12601 attaagtaca agtacagaaa ttttggaaac agggatcaaa gttatcgatt tgcttgcccc
    12661 atatttaaaa ggtgggaaag tcggactatt cggtggtgcc ggtgttggta aaaccgtact
    12721 gatccaagaa ctgatccata atatcgccca agaacatggt ggtatttctg tatttaccgg
    12781 tgtaggtgaa cgtactcgtg aaggtaatga cttgtattat gaaatgaaag attcaggagt
    12841 tatcgaaaaa acagccatgg tgttcggaca aatgaacgaa ccaccaggtg cacgtatgcg
    12901 tgttgctttg actggtttga cgattgcgga atatttccgt gatgtagaag gtcaagatgt
    12961 actgttgttt atcgacaaca ttttccgttt cactcaagct ggatctgaag tatcagcctt
    13021 gttaggacgg atgccttctg cggttggtta tcaaccaaca ttggcaacag aaatgggtca
    13081 attgcaagaa cgtatcacat ctacgaaaaa aggttcgatc acatcgatcc aagcaatcta
    13141 tgtgccagcc gatgactaca ctgacccggc gccggcaaca gcattcgccc atttggatgc
    13201 gacaaccaac ttggaacgta aattaacaga acaagggatt tatccagcgg tagatccatt
    13261 ggcttcttct tcaagtgctt tagcacctga aatcgtggga gaagaacatt ataaagtagc
    13321 aacagaagtc caacacgtat tgcaacgata tcgtgaatta caagatatca ttgctatctt
    13381 aggtatggat gaattatccg atcaagaaaa agtgttagtt tctcgtgccc gcagagtcca
    13441 attcttcttg tcacaaaact ttaacgtggc tgaacaattt actggtcttc caggttcata
    13501 tgtccctgta gaagaaacag tgaaaggatt ccgcgaaatc ttggaaggca aatacgatga
    13561 tcttcctgaa gaagctttcc gaagtgttgg ccgaatcgaa gacgtcgtag aaaaagcgaa
    13621 aacactaggc tactagaaag gggtgcccca tggatcaata tttaacagta aatgtggtaa
    13681 ctcctgccgg tttggtctat gatcaccatg cagctatcgt cgttgcacgt acgacagctg
    13741 gtgagcttgg gattttgcct aaacatgcac caatcatcgt tccattgacg attgatgaag
    13801 ttcgtgtaaa acgaacagat tcagataccc acgtcgattg gatcgctgtt aatggcggaa
    13861 tcatggaagt tcgtgataat gttgtttcaa tcgttgctga tagtgcggaa cgtgaacgtg
    13921 atatcgatgt atctcgtgcg gaacgtgcaa aacaacgcgc agaacgccaa atcgaagaag
    13981 caaaagcaaa acaagatacg aacgaattga aacgggcaac tgttgcgttg caccgagcaa
    14041 tcaatcgtat caaagtatct aagcactcat aaaatgagat gcggatgttt atccgtgttt
    14101 aagaacagta aaaagaggtt atgacagaag tggtcagctt caagacataa gaaggaattt
    14161 acgaaaattg cttctcaaat ttttgtgaaa tctcagctta tttttcgaag aagctacttc
    14221 tggaacaccg tatatcagag gttgtgaaat cagcgttttg tcctgagtat tagagaaaca
    14281 aatggaaaat agttcctcat attttgccgt tttttgagct aataccgagg gtcagatgat
    14341 tgaacaccgt ttatttggaa taagggactg cgacaagact tttgtctcag tccctttttt
    14401 tgcatatttt tagcatttat ttcctaaaaa atgtaagggg attcctatat ttttaagtat
    14461 acttgttttt ccttttatac attttatggt attatcattt tattagttat tataaaacaa
    14521 tcgttagaaa ggacgtcatt atgcaagtat acggaattga tgcggtgctt cgaatcgtga
    14581 gtcatttggc gtttatctac ttagccttct ggtctttacg ttcgttacgc attgaaactt
    14641 ttttcagacc aatgcataat acgcaaatta gaatggcaat cgtacttttt tcaatttttt
    14701 tagggtacac tgcaagtaat tttttcttag aggttatcgc tttatgccga aatcttttcg
    14761 ttagcctgta aattttaaaa aaaggtacta ttttaaaagc aaggatgtta taatagaaaa
    14821 gattttgagt aagtgtatgc tcattggaat tttttggagg gaacaacatg gaagagatca
    14881 tcgtaagagg tggcaatcaa ttaaatggaa cagtaagaat tgaaggagct aaaaatgctg
    14941 ttttgcctat tttagctgct agtttgttag cagaagaagg tattacgaca ttagacaacg
    15001 ttccgattct ttctgatgtc ttcactatga atcaagtgat tcgtcactta aacgtagatg
    15061 tagattttga tgaacaaaag aatcaagtaa caatcgacgc ttcaagacaa ttagaaatcg
    15121 aagcgcctta tgagtatgtt agtcaaatgc gtgcttcaat cgttgtgatg ggtccgctac
    15181 ttgccagaaa tggacatgca aaagtagcta tgcctggtgg atgtgcgatt ggtaaacgac
    15241 caatcgattt gcatttaaaa ggatttcaag ctttaggagc aaaaattatt caaaaaaacg
    15301 gctatatcga agcaattgcg gatgaattga tcggtaacac gatttattta gatttcccta
    15361 gtgtaggtgc tactcaaaat atcatgatgg ctgccgtaaa agcaaaagga acaaccatca
    15421 ttgaaaacgt agctcgcgaa ccagaaatcg ttgatttagc aaacattttg aataaaatgg
    15481 gcgctcaagt ctatggagct ggtactgaaa caatgcgtat tgaaggcgtg gatcatttac
    15541 atgcagtcaa ccactcaatc gtacaagatc gtatcgaagc aggtaccttt atggttgctg
    15601 ctgcaatgac acaaggcaat gtgctgattg cagatgctat ctctgaacat aaccgcccat
    15661 tgatttctaa attgatcgaa atgggtgcag aaatcattga agaagaaggc ggagtccgtg
    15721 tcatcggacc aaaacatatc ttacctacag atgtaaaaac gatgcctcat cctggtttcc
    15781 ctacagatat gcaagctcaa atgacagcta tccaattagt tgcagaaggt acaagtgtgg
    15841 tgactgaaac agtgtttgaa aatcgtttcc aacatttaga agagatgcgc cgtatgaacg
    15901 ctcatgtcaa aatcgacgga aatgtagcaa tcatggatgg aaaccatgaa ttgcaaggtg
    15961 cagaagtata tgcaacagac ttgcgggcag cagcagcatt agttttagct ggcttgaaag
    16021 caaatggaat cacacgtgtg cgtaacttga attatctaga ccgtggatat tataatttcc
    16081 atatcaaact acagcaatta ggtgcagacg tcgaacgtgt agacatggat caaacttctg
    16141 ctgaaaaaac agcacaaacg attgcttaag gaagtggctg aatgagtaac caacgatata
    16201 tcttattaac tttgataaag attttagtgg tgatcttatt gcttatcctt ctttttgtgg
    16261 ccggaacgat gatcggatat ggtgtcatcg gtggcggcaa tccatttaaa gtattccagc
    16321 caagtttgtg gattcatatt cgagactttt ttcattgata aataagaatc acagtggttc
    16381 tagtcgatat gaagtgagcc atgaagcaga acatgataaa agaaaacaga agggaacgtt
    16441 gacgttagtc gcgatccctt tttttagtaa aagaaaagaa ggaatctaat tgatgaagaa
    16501 gatattgatt tatttagtta gaggatatca gcgctttatt tcgcctgcat ttccacctag
    16561 ctgccgttat tacccaacct gttccaatta tatgataaaa gcaattcaaa cccatggtgc
    16621 gctaaaaggg acggtaatgg ggactgcacg gatcttacgc tgtcatcctt ttgtcaaagg
    16681 cggtatcgat tatgtaccat tgacattccg attaacgcga aataagaaag ataaaaaaga
    16741 accagattat aaaaaggttg tgaaaaatac gggtagcact gagcgataaa gaaaaagagg
    16801 aaatttattg tcaaagtaac aactccgcaa ctacttatat gggggacaaa aaatgatcga
    16861 agaactaaac aagaaagatt taccatggtc cttgttatta gatgcagatc ctgataaaga
    16921 aaaagttcaa gtatatgttt ccagagggag tggctggata tggaaagaaa aagaaaaaac
    16981 aataggtgta ctgatctatg tggcaaggga aaaagaatac gaaatcgtca atgtagcagt
    17041 aaccccaacg tatcaaggaa aggggattgg cggaaaatta cttgagacag cttttcagaa
    17101 gctttcacag ctagcttcaa accaaactcg gatcattata cgtactggca ctactagtag
    17161 cgctgcgtta cacctctatc aaaaaatggg ctatgtggag attggtcgag tcaaagacta
    17221 ttttatccat cattactctg agcccatttt tgaaaatgga gatcaattaa gggatcaagt
    17281 gattttagca attcacttac ctaaaaatag ctttaactaa taaactttca attcgagaaa
    17341 atgctttcaa atgctaaata gatacattac aatagcttta gcaaacaaaa aggagaatat
    17401 ttttatggga atattagttt ttgattttgg tggatcggct gtcaaatatg gttgttggga
    17461 tggcaaagag attaaaggta agggacaatt tgcaacgcct gaatcttggg aagaaatgaa
    17521 aacgcaatta tttcaagttt ataaaaaaat actcgtttct tttgaagtcg aaggaattgg
    17581 aatcagctct cctggagtag tgaataatga gaaacaggtg attgagggaa tcagtgcgat
    17641 tccttatatt catggattta atattttccg agatttggaa actctgtttc aactcccagt
    17701 aacgattgaa aatgacgcca actgtgccgg aatggctgaa ttttatgaag gtgctgcccg
    17761 tgattatcaa gatgttgctt ttgttgtggc aggaactggg attggcgggg cgttgttcac
    17821 gaaaggacaa ataaataaag gggcacatct ttacggtgga gaatttgggt tgatgttctt
    17881 agatggcgat aagacattca gtaaacttgg tacagcggta cagatggctt ggcgttattg
    17941 tgaacgcaaa ggtctcgata aaaatgctta taccggaaaa gatgtctttg aattagcaga
    18001 aactggagat gcaatagcaa aagaagaagt tgagagtttt tatacgtatc ttacaaaggg
    18061 attattcagt attcaatttt cgtttgatcc agaagtgatc gtattaggcg gcggggtttc
    18121 tgcaaaagaa gggctcattg atgagatcaa aagccgaatg aagaagctga cagaacaatt
    18181 cgatctgcat gatttcgaac cgcagatttt attatgtgag tacagaaacg atgctaatct
    18241 tataggtgca gcagcaaact atctcgctgt acgtcaagga gagaattaag agctttagag
    18301 aaggtgcagc ttgcataaaa gaagagaatg aaatgaatag gagattttta cctaaggaat
    18361 gttttatttg ctgcagtatg ataaaatatc tgagaggtga aaatgatgtc aaaaaaaaat
    18421 aaagatattg aagtgcgtat agaagaagtg aaaaaagata tcaaaggtaa gaattatgaa
    18481 gtcactcagt tatttatagg gaaaaaaatg attggtgaga tcttagccta tgggccaaaa
    18541 gaatatgaaa ttttctttgg tgaagaagat tttggaaaag aaaaaagtct tgaaaatgcg
    18601 atagaaacag tgattcgaca ctggaatctg cacgaataaa aaaatatcaa aaaaactttc
    18661 aataaagggt tgcaaaaatc tggaaaatta ggtattataa ctaagtcagg ttgatacaaa
    18721 cctttcggag gagtagcgaa gtggctaaac gcgacggact gtaaatccgt tccttagggt
    18781 tcagtggttc gaatccactc tcctccattt cattggggta tagccaagcg gtaaggcaag
    18841 ggactttgac tccctcatgc gttggttcga atccagctac cccagtatac cacaatcgta
    18901 agctctcgtt agttcgagag ctcttttttt ttgctttgct accttgttcc ttgaagattc
    18961 tgctgaatta agatagagtt aagttaacta caagaattgg agggatccac atgaaatgga
    19021 aagaaaaagt agacgaagca gctgaaaagt tatatgattt ggtcaaatca gaaaaataca
    19081 atattgaagt gaatattccg aaaaaaggcg gaaaagcggt ccaggtaaaa tcaaaacgcc
    19141 caacgaatca tacaaaaaaa tggatggcta aaaaccgcta ataataacaa aagatccata
    19201 agtcggcatt ttcatcgatt ttagggtctt ttgttatttt ctaggttgaa catatctaaa
    19261 aaattgtttc tgacaatagg agtagggaga acgatgtgtg tctaaatcct ctgttgatgg
    19321 atagaaacct ttatcttttt cagttgtgaa tcaggtatat accagttata atagaagaaa
    19381 cgaaaggacg ggtgtacgtt atgtcgaatc aattacctgt atatatacag attcatgacc
    19441 aattaaaaaa tgaaatcgaa caaggtatat ggaaagtcgg agaccgtctt ccttcagaaa
    19501 gagaattagc agtgaaattc aatgtcagcc gtatgacgtt gagacaagca attcaaaact
    19561 tggcagatga aggaatctta gaaagaaaga tcggttcggg tacgtatgtt gcgcgagaaa
    19621 aagtacaaga aaaaatgtct ggtgcaacaa gttttacaga aattatggaa tcacaaaatc
    19681 gagtaccgtc tagtcggaca atctcttatt tcttgacttc gccaagctca agtgaaatgg
    19741 aaaaactaaa cttgagtaaa gatgacacga tcttgcgaat ggaacgtatt cgtttcgcag
    19801 atgatgtccc tatttgtttt gaagttgcca gtgttccaca aaagctgatc gatggctaca
    19861 gcaaagcaga gattactgaa tcgttgtatc gcacgctaga agaaaaaggc gggaaaaaga
    19921 tcggtccagc gaatcaaacg attactgctg tgttggcttc tgagaaaatt gctgactatt
    19981 tagaggtaaa acgaagagat gcagttcttc gtttgcgcca gatttcttat tttgaagacg
    20041 gtacgccgtt tgagtatgtg cgtacgcaat acgtaggaaa tcgttttgag ttttatttgg
    20101 aaaaataaaa aacaggtgat ccctgattcc ttattagaaa taaaagagaa tcagaatcac
    20161 ctgtttttat atatgatcag ttatcagttg ctcgtgataa gaaacagaac cctcttcaaa
    20221 ttggacttgt ccgttcagca gctcaatgat ggattcttta aagtggttag cacttttttc
    20281 atctacagca cagatgacgc taacttgatc agtatattgg atttctttta taaaaaaatg
    20341 ttggagttca agataattct gtaattttcc tagttgcgga tacgtgatca tcacagagat
    20401 ctcctgttgc aaggtacctt ctacgattcc aatgtcagac aatgcttgag agaccgcatg
    20461 agtgtatgct cgtattaatc cgcctgtgcc gagtttcgtt cctccaaaat atcgagtgac
    20521 tactgcagct acattgatca gttgattttt tttgaggact tccaacatcg gtacgcccgc
    20581 cgttccactt ggttctccat catcgctgct tcgctggatt tcattttttt ctccaatgat
    20641 gaaggcgctg cagttatggt tcgctttcca atgttctttt tttatttctt gaatgaaatt
    20701 ttttgcttgg tcctctgatt ctattcgtct aagagaacag ataaagcgtg attttttgat
    20761 ctcaatctca ctttgtccat tttcttttat tgtacgatag cgctcgatca tcttgtcacc
    20821 tctttttttc attttcttta ttcagtataa ataaagttct aggttgtttc aacactgtaa
    20881 cggttgcgca attgctgtag tatgcgataa taaagacaaa ggcaggtgga tctggggatg
    20941 caggaacgaa tgaaaaagta cgatgcaatt acgcattatt tgaagaacaa tggcggctct
    21001 caagtaacgt tgacctttac ccaatttgac gaactgctgt ttcccagtaa cggacttccc
    21061 aaaacagcaa gggaaagtac agattggtgg gcaaatgatt ataaacaccc tgaaaaaggt
    21121 gcctatggct ggataaatgc aggctatgaa gtagttgtca tcaatttgga caaagaatat
    21181 gtcgtgttca ataaattagt gaaatctagt tggctatttg attaaataaa ccgcgtttag
    21241 aaaacgttga caaatttctt tctttttata taataaagta acagacgcga agaaaacgtt
    21301 tgcgtagttt gttttaaaaa ggagagaaaa atatggctaa aaaaacaatc atgcttgtat
    21361 gttcggctgg tatgagcaca agtttactag taacaaaaat gcaaaaagct gctgaagcaa
    21421 aaggaatcga ctctgatatt ttcgctgtgt ccgcttctga cgcagataac aatcttgcaa
    21481 ataaagacgt ggatgtgttg ttattaggcc cacaagttcg ctttatgaaa gctgattttg
    21541 agaaacgtct ggaaccaaaa ggcattcctt tagatgtcat caatatggct gattatggta
    21601 tgatgaatgg cgaaaaagtg ttagatcaag caatcgcgct cataggtgaa taaatagaac
    21661 agtataacta tcgaacaagc gatccaaaaa atagatcgct tgttttttcg tatatttttt
    21721 tagggcgaat aatatgaatc atttttgggg tagaaggctt ctgacgagag atattaaagc
    21781 aatagactgt gaggaggtaa atttaccaaa ttatgagaag atcgcagcag tggaacgttt
    21841 gggcaactgg attctttgtc atcgctgtgg aatgaggacg tccgtcattg ttggacagct
    21901 tgcagattac ggttattttt gtacacattg tctatattta gggtgatgcg acactcaaca
    21961 agatttatat ttgtttgatc agcctgaagc aaaacctcga gaagtcgtct ttttttggac
    22021 aggacagctt actgaaaaac aaacggaaat cgcaaagaga atactttgcc attcagaaaa
    22081 aagacatcat cttatttggg ctgtaacagg tgcagggaaa acagagatgc tttatcctat
    22141 tttagtggaa actttaaaag ctggaggaag agtagcgatt tgtacaccgc gagtcgatgt
    22201 ttgtaatgaa ttgtttttac gctatcgtta tgtttttcca gaagaaaaaa tcacgttgct
    22261 ccatgggaat acagcaacgg cttatacctt tacttctttt gttatctgta cgattcatca
    22321 gctataccgt ttttatcggt cctttgattt aatagtgatc gatgagatcg atgcgtttcc
    22381 ttataacggg gatgctgggc tagctcacgc tgtgcaaaca gcaatcagat caaacggccg
    22441 attcatctac ttaagtgcca cgcctgatga gaagttacta aaggaaatca agcagacatt
    22501 tgagctccac aaacttgcct tgcgctttca tcggcgcttg cttcctgaac ccgtgcttgt
    22561 tttcatgaat aattggcgac aaaaatgtgg aaacaaaaag aaaatcaact ctttggtgcg
    22621 gatcattcag caactaatca aagaaaaccg tatcctttta ttttgtccaa gtattacgat
    22681 gatgcatcgt ttaaaaatca cactgcaaga agcttttcca gaatatgaga taacagatgt
    22741 ttcttcacaa gacgatcaac gggcaaagaa agttcagaaa atgcgagaag caatatacga
    22801 gatactgtta accacaatga tcctagaaag aggagtcaca tttgaaagaa tctctgtcat
    22861 cgttttagga gcagatcatc cagtttttac taaatcctct ttggtgcaaa tcgcaggaag
    22921 agctgatcgt aaaggtcctt atacgaacag tcgagtctat tttttctatg aagaaaaaac
    22981 ttcagctatt cgaaaagcct gtcaggaaat caaagaaatg aacgaagaag ggaagcagat
    23041 gctgtgagat gtagttgctg cggtaaagac atcattcaaa atttaacatt cagcgagatc
    23101 atcggagtgt cgaaatctag acttcctcag acatgttcag tttgccgcgc acaattccat
    23161 ttattagaag caaaaggttg tgcaggttgt caaaaaccaa tccatttgaa atacgaggag
    23221 acgaaaaaga aagcaaatac tagtttcgtt tactgcaacg actgtcaaga atggaagaag
    23281 aaatatcctg catatgattt tcaacaccgc gcctttttta cgtacgatga aaagatgcag
    23341 gcttggatca atcggtacaa gtttatggga gatatccgat tagcagggac ttttgcatat
    23401 aaatggactc agataaaaaa aagattaccc ggcatatatt tattgtccaa tacctttatc
    23461 tgaaaaaagg tggctagaaa gaggattcaa tcaagtaagc gagatgttga aagcagcaaa
    23521 aattcctttt cagatgctgc tcaaaagaga gcaacatctg cttgctcaag caaaaaacac
    23581 gcgaaaggaa agattggaga tgcctcagcc ttttgagctt gccgtacctc tttctaagat
    23641 acaacataaa aaa
//
LOCUS       DAFLVO010000042        23653 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.042, whole genome shotgun sequence.
ACCESSION   DAFLVO010000042 DAFLVO010000000
VERSION     DAFLVO010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23653
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.042"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..506)
                     /locus_tag="L1U99_001736"
     CDS             complement(<1..506)
                     /locus_tag="L1U99_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1212275.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQVILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSM"
     gene            779..3250
                     /locus_tag="L1U99_001737"
     CDS             779..3250
                     /locus_tag="L1U99_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBN1212276.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(3353..5089)
                     /locus_tag="L1U99_001738"
     CDS             complement(3353..5089)
                     /locus_tag="L1U99_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBN1212277.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(5086..5790)
                     /locus_tag="L1U99_001739"
     CDS             complement(5086..5790)
                     /locus_tag="L1U99_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1212278.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5921..6424
                     /locus_tag="L1U99_001740"
     CDS             5921..6424
                     /locus_tag="L1U99_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBN1212279.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            6384..6722
                     /locus_tag="L1U99_001741"
     CDS             6384..6722
                     /locus_tag="L1U99_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBN1212280.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6743..8161
                     /gene="ffh"
                     /locus_tag="L1U99_001742"
     CDS             6743..8161
                     /gene="ffh"
                     /locus_tag="L1U99_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBN1212281.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            8273..8851
                     /locus_tag="L1U99_001743"
     CDS             8273..8851
                     /locus_tag="L1U99_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HBN1212282.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8855..9376
                     /locus_tag="L1U99_001744"
     CDS             8855..9376
                     /locus_tag="L1U99_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBN1212283.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(9455..10009)
                     /locus_tag="L1U99_001745"
     CDS             complement(9455..10009)
                     /locus_tag="L1U99_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBN1212284.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            10262..10537
                     /gene="rpsP"
                     /locus_tag="L1U99_001746"
     CDS             10262..10537
                     /gene="rpsP"
                     /locus_tag="L1U99_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBN1212285.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            10549..10800
                     /locus_tag="L1U99_001747"
     CDS             10549..10800
                     /locus_tag="L1U99_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBN1212286.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10925..11716
                     /locus_tag="L1U99_001748"
     CDS             10925..11716
                     /locus_tag="L1U99_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212287.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11886..12407
                     /gene="rimM"
                     /locus_tag="L1U99_001749"
     CDS             11886..12407
                     /gene="rimM"
                     /locus_tag="L1U99_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HBN1212288.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            12397..13158
                     /gene="trmD"
                     /locus_tag="L1U99_001750"
     CDS             12397..13158
                     /gene="trmD"
                     /locus_tag="L1U99_001750"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBN1212289.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            13294..13641
                     /gene="rplS"
                     /locus_tag="L1U99_001751"
     CDS             13294..13641
                     /gene="rplS"
                     /locus_tag="L1U99_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBN1212290.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            14014..14676
                     /locus_tag="L1U99_001752"
     CDS             14014..14676
                     /locus_tag="L1U99_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212291.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            14755..17982
                     /gene="fss3"
                     /locus_tag="L1U99_001753"
     CDS             14755..17982
                     /gene="fss3"
                     /locus_tag="L1U99_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBN1212292.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            18096..18410
                     /locus_tag="L1U99_001754"
     CDS             18096..18410
                     /locus_tag="L1U99_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBN1212293.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            18423..18797
                     /locus_tag="L1U99_001755"
     CDS             18423..18797
                     /locus_tag="L1U99_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBN1212294.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            18807..19151
                     /locus_tag="L1U99_001756"
     CDS             18807..19151
                     /locus_tag="L1U99_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBN1212295.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDVEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            19222..20574
                     /locus_tag="L1U99_001757"
     CDS             19222..20574
                     /locus_tag="L1U99_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBN1212296.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            20634..21776
                     /locus_tag="L1U99_001758"
     CDS             20634..21776
                     /locus_tag="L1U99_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBN1212297.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            21801..22055
                     /locus_tag="L1U99_001759"
     CDS             21801..22055
                     /locus_tag="L1U99_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212298.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            22311..23495
                     /locus_tag="L1U99_001760"
     CDS             22311..23495
                     /locus_tag="L1U99_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBN1212299.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNQKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVNNTRLSDRHKKILEQQSMAIENL
                     II"
     gene            23492..23629
                     /locus_tag="L1U99_001761"
     CDS             23492..23629
                     /locus_tag="L1U99_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBN1212300.1"
                     /translation="MKRGIVMEIVKDILLVFGGSMLGVTVMCLMHASAAADRAMEKKG
                     K"
BASE COUNT         7832 a         4218 c         5073 g         6530 t
ORIGIN      
        1 ttcattgatt tgaactcatc catacacaac accgtcggaa ggaagttcat acgtggctgg
       61 taatgcttcg ttgcttcacg caagatccgt gtcaccgtcc catccgagac gaagtacttc
      121 ttagcgatta gtttacgtga ttgattttcg tacagttcca tgagaatcac ctgcttcagt
      181 tcctttgtta gttgatgatg ttcatcaact aagtccgttt tcgcagaaaa ggtccttcca
      241 caatcatggc agagaaaacg ggtacgtttt aattctaaaa tagttaactt ttctttgact
      301 ttcaacatct gagtgcgtgt cgtataggaa ccgttgcgga taatacgaac cgatcgacag
      361 tgttcacaat aggaagaaga gtcatccaat tttcctttaa taaactgcgc ttgaacgcct
      421 ttatattctt tttcaatcag ccattcttca tcaaaaaata aatgtttatc tgttaatccg
      481 agtaattttc tagtatgatt atccattgag agactccttt ggtaggatga cgttttggtc
      541 gactaaattt taccaaaagt gagtctcttt ttgagttgaa acgaagaaaa agtgttagta
      601 gaaaatcgcc ttcgattttc caccaacaca aaatattata gaaccctttt tttttgctat
      661 atgacaggaa tgaaaggtgt ttgcaagctt aatgtgagga acactttcca tatctgttct
      721 atactggata ggagaagttt ggaaatatcc agaaaacgaa atcaatcgag gtagccacat
      781 gaagaataaa tggataaatc gaagtaaaaa aaagaaagta acacaaagat catcagataa
      841 agtcatccgt ctttttccat cgtataaaga aggattaacg gcagatcaag tcaaggaacg
      901 aatagaaaaa ggtgcagcaa ataattcagt cgatcccaca ttcaaaacaa atcagcaaat
      961 cgtattggaa aacatattta cgtatttcaa tttgatcttt cttatcttag ccattttgct
     1021 ttgtttagta gaatcctata agaacttgac ttttttacca gttatcatag ccaatacagg
     1081 aatcgccatt tttcaggaaa ttcgatccaa aaagatcttg gacgaactaa atgttttaaa
     1141 tacagcaaaa gtcaatgtca tacgagacgg gatagaacaa acaatagata tagaagacct
     1201 tgtaatagat gacattgtta ttttagagac tggatatcaa attccagcag atgcagaggt
     1261 cgtggaaggg aaactgcaag ttaatgaggc tttattgaca ggcgaagcag atgaaataac
     1321 caaagaaata ggtgatccat taatgtccgg cagtttcatt gtttccggaa aagcttacgc
     1381 ccgattagac aaagttggag cagattcgta tatttcccag ctgacagtca aagccaagac
     1441 aatgggagaa ggagaacagt cggagatgat tgcttctctt aatcaattga tcaaatggat
     1501 tgggatcatc attattccta tcggtatcct gcttttttct caaagttact tttttaatgg
     1561 aaacacgatc aaagaaagtg tcgttgcaat ggaagcagca ttgatcggta tgatacctga
     1621 aggactgtac ttgctgacga cgattgcatt agcattaagt gcgactaaac tagcaaagca
     1681 aagagttctt ttacacaata tgaaaagcat tgagacattg gcaagggtaa atgtcctttg
     1741 tgtagataaa acaggaacga tcacagaaaa taaaatgtct gttcaaaaaa tgatcgtctc
     1801 taaaaaacaa gaaataatca gtcagtcaga tcaattggaa gcatgcattg ctgactatgc
     1861 aaaagcgatg gcaggagaca atgcaacaat ggaagctgtt aaagcatatt ttacaaaaac
     1921 cactgatcaa tcctatcacc atgttattcc tttttcttct gtccaaaaat tcagcagtgt
     1981 agcgttggca gacaaggtgt atgttttagg agcgcccgaa atggttttgc gcgatcaatt
     2041 gccggaatat gcggaagagt ttgtttcttt cgctgaaaaa ggctatcgcg tgttggtctt
     2101 tggtgtgtac gatgggattc ttgaagaacc agtattgaca gaagcagtca caccattagg
     2161 ctatattctg attgctaatc ctatcagaaa agaagcaaga gccacatttg attacttcaa
     2221 aaaacagcaa gtagccatca aagtgatttc tggagataat ccgctcaccg tatccaatgt
     2281 agctgtccaa gcagggattt cacatgctga tcagtacgtt gatgcatcta aattatcaga
     2341 agaagaatat gaagcagctg tcgaaaaata tacagttttt ggacgcgtca agccagaaca
     2401 aaagaaaatc ttcgttcaat tgataaagcg taacaataca gtagctatga caggtgatgg
     2461 cgtgaatgat attctagcca tgaaagaagc agactgcagt atagcgatgg cttccggaaa
     2521 tgaagccgcc atgcaggcct cacaagtggt cttacttgat tctgactttt cacgcatgcc
     2581 agaagttgtt gcagaaggac ggcgcgttgt gaacaatatt gagcgatcag ccagcttgtt
     2641 tttagtgaag aatattttct cctttttgct ctcactgttt tcagtgatct ttgctctgac
     2701 ctatccttta gaaccatcac aaatcacatt gattagtttg tttactatcg gacttccatc
     2761 tttcttgctt gctctagaag aaaacaaaaa gcgaatcaga gggaaattca tcatgaatgt
     2821 gatggaaaaa gctgtgccag gtggactaac agatatgatc gtagtcggtg cgttggtgat
     2881 ctgcggggtg actttgaatc taaataaaac agatgtttct acagcatcta ccatgctttt
     2941 gattgcagta gggttcctcg ttctctataa aatctgttca ccgctgaata aattcagaag
     3001 tcagatcatt cttttctgtg ctagcggtaa ctttttttcg gtcatctttt tgcataagct
     3061 gttttcaatc accggtatct cagctgtatc acttttgctg ttgagcattc tatttttctc
     3121 ggcagattcg atttttaggc atttgaccac attggtagaa tatttgtttg aacgtaaaaa
     3181 tgaaaaagag caaaagccgt ttagtcgcgt agctaaaaaa tttctatcga tatttaaacg
     3241 agaaaattga cgaaaagtat ctcaaaaaag agtaaaaaag aacaaccact cgtgtatctt
     3301 tcgaagcagg atgagtcatc caactttaaa acgcacgagc agttgctctt ttttacattt
     3361 tcggaatggt aacggtgaaa gtcgaacctg ttccaagatg actgtctaca gtaatcgtac
     3421 cattaaggag ttgcacgtag tcttttacaa tcgctaaccc taatccggtc ccgcctgaat
     3481 gtcggcttcg cgccttgtct acgcggtaaa aacgctcaaa gatccgttcc tgatcctcaa
     3541 tgtcgatacc tataccaaag tcttggacag aaaacgatag atcatctgtt gcctgatagc
     3601 ggataataat ctcgctgtcg ctttttgaat attggacagc attttcaatt agatttttga
     3661 taattggata aaggatatct gttttagtag taaatggttc gttctttcca atcaatcgaa
     3721 tcgtcaaccg tttcttttcg atgattggct gataattttg aacgatttgc tggaaataag
     3781 gttctgtata aattgtctgg atctcgtaag aattctcgcc atcttttgac agctggatga
     3841 tttcccgaat cagtttatct aaccggatcg catctttttg catgatctca agaaaagaag
     3901 tcagagtttg cgggtcatct tttgcaccat ccagtaaagt ctcggtaaaa ccaatcagtg
     3961 aagtcacagg agtttttaat tcgtgagaga cgttgccaac gaaatccttt tgtagctttt
     4021 ctaaacgtcg cactttcgtt aagtcatacg ccacccctag aatctgtccg gtaccttctg
     4081 aattagtaaa gtagcgcaaa ctcaagtcta atgtctgccg accttctgta agggtgatct
     4141 cctgatggat cagcggatgc tcaggagtca cttgatgaat cagctgaatg agttttggct
     4201 cttgaatgac ttctgtgtac cgctgttcag gttgatagct taccacgttt aaatgtagct
     4261 gcatctttgg attaagcagt agtaaacgag aatcagcatc atcaatcagg aatacgccaa
     4321 tcatcagttc gttcagtaac gtatataatt gctcttctgt ggtagtacac gcccgataca
     4381 tcttactcat ttgttcgctc aacgcattaa tcgtctgata caattcttcc cattgatcgg
     4441 gtgtttgcat gattacttcc gcctgattag gattttgcac catttttttt agtacgggca
     4501 gcacggtttt caatggctgg tttttttgat agatcagata atagatcatt cctgcaagaa
     4561 caaggaagaa agacagaaag aagaaaaaga cccaacggcg aaaactctca gttctcggta
     4621 aaaaaccgct tgtcggttct gcgatacgta aaatggcttc taactggcca ctttttttga
     4681 ctggtaatgc gacatataaa agatcctcat tcaaagtagt acttttgcgc aaagcgctac
     4741 ctaggttccc accattcaat acggctttga tttcgggacg ggagtttcgc tgttcattca
     4801 atgtttcatt gtttgtgtca aataagatct ttccagtagc atccattaaa gtaatccgtt
     4861 cgttcgactg atggacgaat tcttccaaag cagttttgtt ttgcgctgct tggaggtttt
     4921 cgacatctaa ttgccggatc agcagttgtg ctttttttgt caggtagctt tcttgctgtt
     4981 ccacgatctg ctgttgaaaa taatgggaaa tcaattgcca gccaccaaaa aacaaactaa
     5041 ctaaaagaat aagaaagaag agacgttcat aaattttttt ccatttcatc gtttgggttc
     5101 ctgaaactta tagccaaatc ctctaatagt caccaagtac tttgggtgtt ttggatctcg
     5161 ctcgattttt tctcgcaaat gactaacgtg tacatctacg attcggcttt gtcctgcgaa
     5221 gtcaaaattc caaatgcggt ctagcaatgt gtctcggtcg atcacacggt cttttcgttt
     5281 catgaaataa acaagtaatt caaattcttt cggtgttagt tcaatcagat ggtcgtctac
     5341 ggtcacttga taattggtca aatcagcagt gatttgtcca atcgatagat attcaggctc
     5401 agcttcatct tttgattgct tacgaggttc aattcgtctg aatattgctt tcatacgggc
     5461 taatacttcg cgaggactaa atggtttggt caaatagtcg tcagcaccta tttctaggcc
     5521 aatgatccga tccacttggt catctttagc cgtcagcatc aaaatcggtg tttcattttt
     5581 ttcttgacgc agccgctgag tgatctccat gccatccatc gttggaagca tcacatctaa
     5641 aatgatgaaa tcaaatgatt gttctaatgc taattctaat ccttcgcctc catctgtggc
     5701 actggttacc ttgtagcctt ctttttccaa attgaacgtc aagagcgtta caatagaagg
     5761 ttcatcatca acaactagta tttttttcat tcaaatctcc tttaaatagg tttcattctg
     5821 tttatatttt agcatagaat cagtacaaag ggctatttta caaaagaaat aaatggtata
     5881 ataggaaggc actttgctga atagaaagga agagcagtca atgattggaa tcagtgcatg
     5941 tttaggcggt ctggcctgtc gctatgatgg acagaaaaaa gaagtaccag aattgatgga
     6001 actagttgaa actggagaag ctgtcatggt ctgtccagaa gtgatcggcg gattaccaat
     6061 tcctagagat cccgctgaaa tcattggtgg aaatggattc gatgtgtgga aagatcaagc
     6121 aaaagtatgg acgacaagcg gcgaagatgt aacggaagcg tacaaaaatg gcgcgatcaa
     6181 agcctatcaa aaattgcagg aaaaacacat tgatctagtc atcatgaagg aaaaaagccc
     6241 ttcatgcgga acccattcga tttatgacgg aagtttttcc ggaataaaaa aaaatggtgc
     6301 cggagtggct actgcttatt ttattcagca aaaaatgact gtgctctctg atgaagaatg
     6361 gctgaaaact agaggtgagc agaatggaaa tcgaaaagac caatcgaatg aacgcgctct
     6421 ttgaatttta ttcgacctta ttgacagaaa aacaaatgaa ctacatggaa ttatattatg
     6481 cagatgattt ttcattaggt gagatcgcgg aagaatacga agtaagccga caagcagtat
     6541 atgacaatat caagcggaca agcaagatct tggaggatta tgaaaaaaaa ctccatcttt
     6601 tttctaatta tattgttcga gaacaggtat tggaaaatat gactgcatat attacagata
     6661 agtacccgga agataaaaaa ctacttgaat atgtacagca aattcaagca atcgaagaat
     6721 aaataaaagg aatgaagaaa atatggcatt tgaaagctta actgaacgtc tccagcaggc
     6781 gatgggaaaa ataagaaaaa aaggaaaagt atcagaagct gacgtaaaag aaatgatgcg
     6841 ggaaatccgc cttgccttac tagaagccga tgttaacttg caagtagtca aagattttac
     6901 taagcgcgta cgcgaacgtg cggtaggggc agaagtgctg gaaagtttat cacctgcaca
     6961 acaaatcgta aaaatcgttg atgaagaatt gacgatcaca cttggttctg aaacagcaga
     7021 gttaaataaa tcaccaaaaa taccaactgt tatcatgatg gctggtcttc aaggggcagg
     7081 taaaacgacc tttactggta aattagccaa ttatttaaag aaaaatgaaa atgctcgtcc
     7141 gctcctaatc gcaggggacg tatatcgacc agctgcgatc gaccaattga aagtattagg
     7201 tcaacagcta gacgttcctg tatttgatat gggaactgaa gtcagcccgg tagagatcgt
     7261 ccgtcaaggg atggagttag caaaagaaaa gaaaaacgac tatgtattga tcgatacggc
     7321 aggacgtctg catatcgatg aaacattgat ggatgagttg aaacaaatca aagaattgac
     7381 gcaaccaaat gagattttgc ttgttgtcga tgccatgact ggtcaagatg ccgtcaacgt
     7441 agctgatagc ttcaaccagc aattaggtat tacaggggtc gtcatcacta aacttgatgg
     7501 ggatactcga ggcggggcag cactatcgat ccgctcagtg acaggcgcac caatcaaatt
     7561 catcggttct ggtgaaaaat tgactgactt agaagtattc cacccagatc gtatggctag
     7621 ccgtatcctt ggtatggggg atatgctgac attgattgaa aaagcgcagc aagactacga
     7681 cgagaaaaaa gcggaagaac ttgcacagaa aatgcgggaa aattcattcg atttcaatga
     7741 ctttattgaa cagcttgatc aagtgatggg tatgggccca ctggaagatc taatcaaaat
     7801 gatcccagga atgaatcaag tccctggaat cgaaaacgtc aaggtagatc caaaagatgt
     7861 tgaacgcaaa aaagcgatgg tttattctat gacgccagca gaaagagcaa atcctgatct
     7921 gttgaaccca agccgtcgtc gccgaattgc tgccggttct ggaaacagtg ttgttgaagt
     7981 gaatcgaatg atcaaacaat tcaaggaatc aagaaaaatg atgcagcaaa tgtccaaagg
     8041 ggatatgaac atcccaggta tggaccaaat gtttggttca ggcgtcaaag gaaaactagg
     8101 caaaatggcg atgaatcgaa tgatcaagaa aaataagaag aaaaagaaaa aacggaaata
     8161 agatgaaaaa aacagcttcg gtacagactg aaaatgtcta ctgccggagc ttttctatca
     8221 gcaattttta ttctttacta atacaattac tctaaacgaa gaggtggcac agatgagatg
     8281 tccgtggagt gaacaaacag aaagtatgcg gcaatatcat gatactgtct ggggtgttcc
     8341 tgaatatgat gaccaaaagc tgttccgaaa attgatgctt gatattaatc aagccggatt
     8401 gagctggcag acgattttaa ataaaagtga agcattcgat gaagcatatg atcgattcga
     8461 tatcaaaaaa gtcgcaaatt atggagaaac aaaaatcagt gaactaatgg aaaacaaagg
     8521 aattattcgt aaccgaagaa aaatcgaagc agccgtccaa aacgccaaag cagtcttgaa
     8581 aattcaagaa gaaatcggca gtttttcaga gtatctttgg tcgttttcta atggaaaaat
     8641 cgttgattct tcttatcatt cacaagaaga agtcccaaca acaagtcctc tttcagatga
     8701 attagcaaaa gatctaaaga aaagaggatt taaatttatc ggaagcacaa caatctatgc
     8761 ttttttagaa gctgtcggga tcatcaatga tcaccttgac agttgtttcc gcaaagaaga
     8821 ggtcgtacgt atcggcagaa agggcgaata aagcatgcga aaaatcatat tttatggtgc
     8881 tataagttta gatggctatt tggcaacgaa aacggatgat cttcaatggc tttttgacac
     8941 tccaacaggt aagcaaacta cttatgaagc tttttatgaa acaatcgata cgaccatcat
     9001 gggcagaaaa acttatcagg aagcaaaaaa atatttggag accgaagcaa tttatccaga
     9061 gaaaaagaat ttcgtttttt ccacccacgc acaattacaa ttgccagatg ctgaggtcgt
     9121 aaacgaagat cctgttgctt ttctaaaaaa tctacaaatg acagaaggaa aagatatctg
     9181 ggttgtgggt ggcggtcgat tgatcaaacc gctattggaa catcaaatga ttgatgaatg
     9241 gtatatccag attacccctg tattattagg ggacgggatt cctttattcc aaaaaggaac
     9301 atatgaagcg cgttttgaaa tgctagacac gacacgattc ggtgaattta tcgaattgca
     9361 ttatgtacga aagtagaagt aaataaaata aaaaaggcaa ctatatgcag aaatgtcctg
     9421 tacatagttg ccttttttat taccgttatg ctttttactc tgttaatttg ttagaaaaat
     9481 ctagatacgc atctaaaatc gtttggaaga aacttaatgt tccttcaacg atattaccat
     9541 tttcatcaat tagattcgca acgtttccga tatatgcttc cggttgctgc aaggttggca
     9601 cattcaaaaa gacaagtgat tggcgtagat ggtggtttgc gccaaagccg ccgatcccac
     9661 ctggtgatgc agtaacgact aaacctggtt tatgatccca aacactgtgt ccataaggtc
     9721 ttgagcctac atctaaagca tttttcaata ctgctggcac agaacggttg tattcaggag
     9781 taacgaaaac gacaccgtct agtcccctca cttcctcacg aaaacgagtc cattcagcag
     9841 gagcctgttc tggagtttcg agatcctcat tgtaaaatgg cagatcatcg atttttacaa
     9901 atacactttc gtacccttca ggaagcaatt tcgcaaaagc ttctgctact tttttgttgt
     9961 aagaatcttt tcttaaacta ccaataaaaa atccaatttt ttttgtcata cgatttttcc
    10021 tccttcaaac tatctataat aatcttacaa aagataagta actggagcaa ataaaaacac
    10081 ttactgacaa aagctacata gaagatagat tacttatttt taacaaaaaa gaagtctaaa
    10141 atcttctatt ttctaaaaaa aatcgaattt aatcaagctg taaagaaaaa aagctttaca
    10201 gggtaaaaaa aaactgttac actacatctt gtgaataaaa caatggaggt ggaaataaat
    10261 aatggcagtt aaaatccgtt taaaacgtat gggttctaaa aagagtccgt tttaccgtat
    10321 cgtcgtagct gattcacgtt ctcctcgtga tggacgtttc atcgaaactg taggtactta
    10381 caatcctttg aaagaccctg cagaagtagt tttaaaagaa gacttagttc ttgactggtt
    10441 atcaaaaggt gcacaacctt ctgacactgt acgtaacatc ctttcaaaag aaggcgttat
    10501 gcaaaaacac cacgaagcta aattctcaaa gaaataaggt gaccggatat gaaagattta
    10561 agcgacttag tcttaacaat cgttcgtccg ctagtcactt atcctgatca agtcaagtta
    10621 gacgtcgtag agtcgaaaga cttttacgag tacaatctaa cagtggctcc tgaagatatt
    10681 ggccgtatca ttggaaaaca agggcgtgtt gctaaagcaa tccgcacaat cgtttacggt
    10741 gttcggatca atgcaccgaa aaaagtgcgt ttgaatatca tcgatgataa ggaaaagtaa
    10801 ataaacgtgc tgtactcgaa ttttcgagtg cagctttttt gtttttttta ttaattgaag
    10861 aaatgattat ttggcaaaac aagcaagaaa gcgtatcctt ataggaggag ggagtgaaca
    10921 gccaatgaga aagaaaatgt tatttattcc atttgctcta ttgttaagcg cttgtagttc
    10981 ggttactcaa gaatcagaca atacacatct atcaagcagt atatctgaaa ctgttaccag
    11041 tccagaaaaa agtagtacca aaacggcttc caccactgaa caaacaatgg ctacctcaaa
    11101 taatgagaaa aagactgctt tagaccagtt gaaagaacaa cagccaaatg ttcccatgcc
    11161 tctagatgta ccagtctctt caggctatct caatatcgca gcgacacata caaagcaagg
    11221 ttattctatt ttatattaca gaacagatcg tcccctcggg ttgaatgctg acgaattgaa
    11281 tcaagaaacg cctattgcaa cctatctata tcaatatggg tttgcttcta gtcaagaaac
    11341 aatccaagtt ttgcagccat ttgagatcga cacaaatggt cagcaagtgg acttaggttc
    11401 tcgaatcaca gggtatcagc aaggtgcagc aggttcaagt tttcttgaat ggcaagaagg
    11461 aaactggcgt attcgaatcc gtgggaataa tatagaaggc caagatccct tactattagc
    11521 taaagaaatc gtagcttatt tggaagaaaa cagtctacca gcacctgaac aatttggtaa
    11581 aattactgtt gatatgggtg atacgacgaa tcgagccgta gaagtaagct ggcaagaacc
    11641 gaaaaatgcc tatacgatca ctcatcaaga tcctatgtct gcgttgaaga tggcagtttc
    11701 tatgaagagg ttgtgaaatc agcgcgctga tctgagccca tcatttaact ccaagtcaca
    11761 ggaagtaatc aaaaatagca cgccgcattt ttgcataatt ttggcttaat accttaaaag
    11821 aaaactagaa ttgcctcttc acacatgcta aaataaaaca gacaaaaaag aaatggggat
    11881 ataagttgac tgaatacttg aatgtaggaa aaatcgtaaa cacacaaggt atcaaaggcg
    11941 aagtccgtgt tatctcaaca acggatttcc cagaagaacg ttacaaaaaa ggaacggtgc
    12001 taacactatt ccaagacgga aaagcacctg tggaattaac agtcaaaagt catcgcaaac
    12061 ataaaaattt tgacttattg agttttgaag gacatccttc tatcaatgat gtggaaaaat
    12121 atcgggatgg catattaaaa gtgtcaaaag acaactctgt agatctagct gaaaatgaat
    12181 tctattacca tgagatcatc ggtctgcatg tattagaaga tggaactgag ttaggtaaag
    12241 taaaagaaat cttgtcacca ggtgccaatg atgtttgggt cgttcaacgt ccgaaaaaag
    12301 ctgatatatt gcttccatat atcgcttctg tcgtcaaaga agtcgattta gaagctggag
    12361 tggtccgtgt agaaattcca gaaggactga ttgacgatga agattgatgt attgacttta
    12421 tttccaagaa tgtttgaagg tcctatgggg gaatccatca tcggtaaggc tgtagataaa
    12481 ggattattag atatcaatat ctctaacttc cgcgattatt cagataacaa acatcagaca
    12541 gtagatgatt atccatacgg cggtggagca ggtatgctgc tcaaagtcca gcccatctat
    12601 gataacatcc aagccattga aaaagctgca ccggatgtca aaaaaagagt aattcttctt
    12661 gacccagctg gtaaacgatt cgatcagaaa atggcagaag aattttcaca agaagaacac
    12721 ttagtattca tttgtggtca ttatgaggga tatgatgaac gtatccgcac attagtgaca
    12781 gatgaagttt ccttaggaga ttatgtcctt actgggggag aattaggtgc gatggtcatg
    12841 atcgatgcaa cagttcggct tttgccagat gtgttaggga atcagacttc agctcaaacg
    12901 gattcttatt caaccggttt attggaacat ccccaatata ctcgcccggc agaatataaa
    12961 gggatgaaag taccagaagt attgacaaat ggaaatcata aattgattga agaatggcaa
    13021 ttaaaagaat cactaagaag gacctatcaa cgtcggcctg atcttttgga aacacttgaa
    13081 tggacacctc aaatgacgaa atttttagaa gaaatcaaga aagaagaaca agaaaaaaca
    13141 gcagatgaag ccaagtgact ttttctaaaa tcttctttac agtaggttga taatatgtta
    13201 gtattttatg gtgagtgcaa aagcacttaa ctattacgat attccgctgt gagaaaagct
    13261 cataagaata tttggaataa ggagaagaaa accatgaatc cattaatcga agaattaaca
    13321 aaagaacaat tacgttctga catcccagcg ttccgccctg gtgacactgt gcgtgttcac
    13381 gcaaaagttg ttgaaggtac tcgtgaacgt atccagttat ttgaaggtgt tgttatcaaa
    13441 cgccgcggtg ctggaatcag cgaaacttat acagtacgta aagtttctaa cggagtgggc
    13501 gttgaacgta cattcccatt gcatacacca cgtgttgcaa aaatcgaagt agttcgctac
    13561 ggtaaagtac gtcgtgcaaa attgtactac ctacgtgcat tacacggaaa agctgctcgt
    13621 atcaaagaaa tcagaagata aacacggaaa acttccttgg aaatctgaaa tttgtgaaaa
    13681 gtccttgtat atcaagggct ttttcttttt tctctatcac agttttaagc catttttggc
    13741 tgttttggac catttttcaa tcatattccc ttaaaaattg tcctagattg tccgacattg
    13801 actatcagtg tcgtcaaaat agggcaaaat ttagtagtca gcttgacgac aaatataata
    13861 cgaaaaatac caaaacattt accgaattta gcaacttttg aacccaagtt tctcaaaggg
    13921 tcagctatta gcaaaaaaga caaaacatgt acttttctac taaaaagttg atgtgatagg
    13981 cttctatcta aataactatt aggagttttt atcgtgaagc aaaatgatgg acgtatcatt
    14041 tggaaaaatc aaagtgagtt aaaactgatt ttaacaatta atgaattcat cgaaaaacac
    14101 ggaattacat ctagccgtca ataccagaaa aagctatcag aaaatccaaa ttctgcacca
    14161 agtatgtggt tcattaacaa aaaatatgga tcatgggaga atttattgat tagtatagga
    14221 cgagaaaata ctgggtatgg aaaatgggct agaatgtcag aacaagaatt attggaaata
    14281 gtagaagcct ttattaagtg cgagaagata acctctcaac gaatgtacga acaaaaatca
    14341 gtagggaaga atattccttc acttagtacc attaaaaaga tgttaggaga tatacgtcca
    14401 ctttttaaag aaaaaaatga tggatctcga tttactgatt tcgaactgct gttagaacta
    14461 aaaaatgaaa taatccgatt aaaactacag gatgatttat caatgacaaa gtttcgaaaa
    14521 ctagttcaat ccccaaaact accatcagtt gatacaatta tgaaaagaac gaacaaaaat
    14581 tgggaggaat tgatggcaga gattggattt gattatcgaa gaatcaaaat ttataagcag
    14641 agaaacaacc tatccaagac aaagaaaact aaatagtatc actctaaatc agacgttcaa
    14701 aattaaaatt tggacgtctt ttttattacc caaaaacgaa aggagattta ttttatgaaa
    14761 aagccaagat ttaagaattg gcgtttgctc gcaacactga gtctattatg ccaaacaatt
    14821 ggtggatcgc ttggcccaac gattgccttt gctgatgaaa ttactcatcc acaaacggta
    14881 actgtggaat tggatttggc tcaccagtat gctgtcgaag gtacatttag cgatggtcgt
    14941 cccatgtcag aagttaccgt tccgcactat gcagtttaca atggtgtgaa gcaagatatt
    15001 ttctgtattg agccaggggt gccgatttac aatgagttca ctcctggtta tgagaaaaat
    15061 ccattgcctg atatgtcgga gaaagcgaaa ttagtttccg ttttatggaa ggaagctggt
    15121 acggatgtgg atacacatat tgtggcccag aagatgattt ggcaagaagt taatggctac
    15181 acgcttcact caattaaacg ttctgatggt agtgcagtaa atatcgcagc cattgagtca
    15241 aaaatcaatc aagccattgc ggattatcaa aagaaaccaa gcttccataa ctccacagtg
    15301 aaaaccgtgt taggtcaatc gactactgtg acagatacga acggcttgaa tttatcggag
    15361 tttgatgaag ttgtcgagaa tatcgcaaat attgattatc gtgtgaacgg caatcaacta
    15421 gtgattactc caaatgccaa ttcaaaagag agtggtgaat taaccctaaa gaagtcagct
    15481 aatacaggaa caccggtagc ttataaaatg gctggtcaac aaactttgat ggcgggggca
    15541 attgataagc ccaataccta cacaatcaaa attgatgtgg aaactgaggg ttctttgaag
    15601 attaaaaaag tcgataaaga aacaggaaat gttgtaccgg gaaccgtttt ccatttagac
    15661 tttggaaaaa cattacctgc aaaagacgtg accaccgata aagaaggcat tgcgacattg
    15721 gatgagattc ctcatggcgc gaaagtaacc attactgaaa aatcagtgcc agctccttat
    15781 acgattgaca ctacaccaat caccgcaacc attaaatctg gtgagactat ttctgtgact
    15841 tcaaaaaata ctcgcgaaaa aggtcaaatc attttgaata aaatgggggt ggaaacagga
    15901 actgatcttt ggaacgacaa atactcatta gccggaaata cgtttgccat tcgcaaagac
    15961 agtccaaccg gtgaaattgt ccaagaaatg accacggatg aaaaaggtca tgcggaaaca
    16021 ccaaaagaga ttgccaatgc gttggaattg ggaacctatt atgtgaccga aaccaaagct
    16081 agtaatggct ttgtgaatac ctttaaacca gtaaaagtcg aattgaacta tgtcaatcaa
    16141 accgtggctc ttgttaccag taacgtaaaa gggcaaaacc aagaaatcac tggtgaaacc
    16201 actttgacaa aagaagacaa agataccggt aatgaaactc aaggtaaagc tgagtttaaa
    16261 ggagctgaat atactctctt tactgcaaaa gatggtcaag cggtcaaatg gagtgaggct
    16321 tttaaaccag agttagtgaa gggaacgaaa gcttctgatg aaacggtgac tttgacttta
    16381 gatgaaaaga atcaagttgc tgttaaacac ttagcgatta atgagtatta ctggcaagaa
    16441 accaaagcac ctgaaggata taccttggat gaaacaaagt accctgtttc catcaaaaag
    16501 gtggatgata acgaaaaaaa tgccgtgatt acccgagatg ttacggcaaa agaacaagtc
    16561 attcgctttg gctttgattt ctttaaattt gctggatcag ctgctgggac tgccgaaact
    16621 ggcttcaatg atctgacctt taaagtatcg ccattggaag gaaccagtga gattacaggt
    16681 gccgaagatg aagcaattac agcttataac gagcaactag gttttgatgg ctatggcaag
    16741 tttgaaaatc ttccttatgg ggattattta cttgaagaag tagaggctcc agaaggattt
    16801 caaaaaatta cgccattaga aatccgttct acttttaaag aaaataaagc ggattacact
    16861 aagagtgaat acatttttac gattaccgaa aaaggacaaa aacaaccaat taaaacggtg
    16921 accgttcctt acgagaaact gacgaataaa gcattttctg ttagcttgaa tcgtttgatg
    16981 ctctatgatt tacctgaaga agaagatagc ttaacttctc ttgggacttg gaaagacgga
    17041 ggcaaagaat tgacagacct tgattctacc gagctagttg ataaattgag ctataacttg
    17101 catgaaatca aagaagactg gtatgtggta gcgcaagcca ttgatgtgga agcgacaaaa
    17161 gctgcccaag aaaaagatga aaaagccaaa ccagtggtaa ttgccgaaac aaccgcaacg
    17221 ttggcgaata aagagaaaac aggaacttgg aaaattttgc ataaattaac cgcagaacaa
    17281 gttttggata aaaccatcgt cttattcaac tatgtgtatg aaaacaagaa accctatgaa
    17341 gcaggtgatg atccagtagc gaaagatgct agcttgaaca atcaagccca aactgtcaat
    17401 tgtacggtgg aacgccatgt ttccatccaa acaaaagccc acctagaaga tggttcgcaa
    17461 acctttactc atggggatgt ggtggatatg ttcgatgatg tgtcgattac ccatgatgta
    17521 ctggatggct caaaagaagc ttttgaaaca attctgtatg cattacttcc ggataatacg
    17581 accaaagaaa tttggaaatc tggcaaaatt gattatgaag tgaatgacaa agaattcact
    17641 aaaaccgtac ttgcggaaaa agtggacaca agtaaatatc cagaaggtac aagttttacc
    17701 ttcaaagaaa ttaactatgg caaagacgga aacatcaatg ggaaacacaa tgaggatcta
    17761 aaagaaaaaa ctcaaacttt aacacctaaa aaagttccga caacaccaag tgcaccagaa
    17821 caaccggaaa taccaactgt tccaagtgac tctcaagaat ctagtcctac agtaaagaca
    17881 ttcccacaaa caggggagaa aaattctaat gttctgctgt ttattgggtt taccttgatc
    17941 tttgcgactg ctgggtatta tttctggaat cgccgaaact aaggtgatgt gatgaaacaa
    18001 ctaaatagga aaaaccaacg tgcgcgaccg cctcctaaaa aaagtggtcg cgctattttt
    18061 gtatccaaaa ctaaaaatga aaagaggaaa agaagatgga attgaaattt gttgtgccag
    18121 atatggccga aacctttgga aagataaggt atgccggcga aggcgaagtt ttaactgaag
    18181 gatatgggcg gaatactaca gtaattggtc gtagttatca tttgtattcc agtaagcaac
    18241 gagccgatga tattgaagtg gtggtagctg cggaagccgg cgaaaaggat tttgatcaag
    18301 atcaaccact aaaagccgtg aatccccatt tggttgccaa aggctatgag attgagaatc
    18361 gtgggtttac cgactacgtg ttgtatgtcg atgatttagt gaaagcatag gaggaaaaga
    18421 agatgagatt aacagaaggt attgttgtag attcaggact aacgtttggg aaattacgat
    18481 tttccgcatt acgccgagaa gtacggaagc aaaatgagga tggaacggtt agtaacgagg
    18541 taaaagaacg gacttataat ttgaaatcct ctgcgcaagg tcgaatgatc caagttagta
    18601 tcccagcaaa tgtaccctta cgcgagtttg cctatgacgc agaggtagag ttggtcaatc
    18661 caatcatgga tacggtcgcc aattatgttt tccgagaagg aactactgtc aattggttca
    18721 ttaaggccga tgatttagtc ttgaaacgac aaccagatca gggaaattct acaaaccaaa
    18781 atgaaggaaa gaaataggtg aagcgtatgg aaattaatgt tgaacatatt ttagattgtc
    18841 tcgatcaata tggaaaaggt gagctaacgg aggaacaact cactaaagca ttaacctatg
    18901 atgaaaaaat gtttctgatt atgcatcaag ggttactgga agtaggtaac gatgtcgaag
    18961 aagattttga tgtactgaat tggttagggg aagaagagtc cttctttatg gttatcgaag
    19021 taaatgaaag tctatgtcga gaagccgaaa ccgtattgga agaaattggt gtggaaatgc
    19081 cggatgccat tgaagttttt ttaaagcaac tagtggaaac gaaacaactc cctatagcag
    19141 taaatgacta gcataactgc ttgaaattgg atcaatgaaa tcctatgaag cttttttcga
    19201 ttggaggtgg aaaccataaa aatgtacaaa gggcatcgta tacgggcagg agatcagcac
    19261 ttggtttatc actttgttct tggctggcta ctcgctctgt tcatcggttg gatgagcgtc
    19321 ttttattttc aagagcttag acaatttgat atttctaagc tatcactttc tactatagaa
    19381 atcgttcgtt ctataaaaga tttaatctat ttgctaggaa gtctcgttct ttcaggaagc
    19441 acgatgttgc tttatataca cttttttcag gatcattggc gcagtttgtg gcatcgacaa
    19501 aagctagccc ggatgattct agaaaatcat tggtacgaag taaaacaaac tcagagtgaa
    19561 ggatttttca aagacctcaa tagtagtcga accaaagaga caatcagtta cttccccaaa
    19621 atctattacc gtatgaagga tggtttactt tctattcgcg ttcaaatttc actgggaaaa
    19681 tatcaagatc agcttttaaa gctggaaaag aagttagaaa gtggtctata ttgtgaacta
    19741 gtagaaaagg aactcaaaga ctcctatgtg gagtacactt tactgtatga tataattgcc
    19801 aatcgaattg ggatagacga agtagtggca gaaagtgggg ctttgcgatt gatgaaaaat
    19861 caagtatggg cttatgattc tttacctcat atgttaatcg ctggcggcac aggtggtggg
    19921 aagacttact ttttactcac tatcatcgag gctttattaa aatctgatgc cgagcttttt
    19981 gttcttgatc ccaaaaatgc ggacttagcc gatttaggta cggtaatgcc tcatgtctat
    20041 tcccaaaagg aggaaatttc tgcttgtgtg gaagatttct atgagcgcat gatgactcgt
    20101 agcaaggcaa tgaaagaaat gcccaactac aaaacaggag agaattatgc gtttcttgga
    20161 cttccaccaa actttttaat ctttgatgaa tacgtggttt atatggaaat gttaacgacg
    20221 aaggaaagtg cggtgatttt gaataagctc aaacaaatcg tgatgttagg tcgtcaatct
    20281 ggtttctttc tgattctagc ttgtcaaaga ccggatgcga aatatttagg agacgggatt
    20341 cgcgatcaat ttaatttccg ggtggctttg ggtcgtatga gtgaactggg atattccatg
    20401 atgtttggcg aggttgataa aaaattcttt atgaagcgta tcaaaggtcg aggctatgta
    20461 gatacgggag ggagtgtgat tagtgagttt tatacgccac ttgtaccaaa aggatatgat
    20521 ttcttaaggg aaattagcga cattggtgga ttaaacgtta atacggaagg ataaaataat
    20581 agtatgtagc ctaggagtgt caagaatcct gggctttttt tacgaggtga tttatgacat
    20641 ttttagattt attcgctggg attggtggct tttgcttagg tatggaacaa gcgggtcacc
    20701 agtgtatcgg cttttgtgaa attgatgatt ttgctcgcca gagttataag gcaatccatg
    20761 atacaagtaa ggaggtggaa atgcatgaca tcacaagtgt atcagacgag tttattcaat
    20821 ctctcggacc agtggatatc ctttgcggtg gatttccgtg ccaagctttt tcaattgcgg
    20881 gaaagcggca aggattttcc gatactcgag gtactttatt ctttgaaatc gctcggttcg
    20941 ccgctattct ccaacctaag tttttattcc ttgagaacgt ccggggatta ctcaatcacg
    21001 aaggaggggc tacgttcgag acgatcctcc gaacgctgga tggattgggg tatgatgtgg
    21061 aatggcaagt gcttaactca aaggcctacg ttccccaaaa ccgtgagcgg atcttcctta
    21121 tcggacattc tcgagacgca tgtaccgaac aagtatttcc tatcattgga tcgtctccaa
    21181 catctgatca aaacatcaga aacttattaa atatcaaccc ttccaatcga ggaatggggg
    21241 gacaagtcta tgggtcagat gacgtagcgc ctaccttgac cggtgatgaa ggaatcaaaa
    21301 tcgcattgcc ggtagatgat ggaatttctg tagcgggtat gttactggga aattttgaac
    21361 aaggcaatcg ggtttatgag ataactggaa cagcgcctac tttgtcaacg aaacaaggcg
    21421 gaacgaagat catgcttcgg aaaaacgaaa cagaatatca agaggtgaag ccagggaaca
    21481 gtgtgaacct ggcttttcct aattccacaa gtcgtcgagg ccgtctggga aaacaaagtg
    21541 tgcatacctt attaacagga gaccaacaag cagtcgtcac ggatcagtat caaattcgaa
    21601 agttaacacc tagggagtgc tggcggcttc agggctttcc ggactgggct tttgatcgag
    21661 cttctcaagt caattcagat agtcagttgt ataagcaggc tggaaattct gtaacagttc
    21721 cggtcatttt tgatattgct agaagattaa aggaggtaaa aacagatgat ttatgatgag
    21781 ttgattgggg aatctactgg gtgattggca agattcagtc agatccggaa ttggaagaag
    21841 aactgtaccg gctcaatttt gatattcgca aaaacggggt gaaagtccct gatgatccgt
    21901 atgtaattga tgaggaaacg gatgctcgaa tggagctgaa tcaagtcatc agtgaattgg
    21961 aacgaattgc ggactttgct aaagaacctg atatccgcca atacttgttt gagataaaag
    22021 cagagttgga aattgagggt attaccgcgg agtaacggcc aaataaacca ctgataggca
    22081 ctgaccgcgg gggatttgcg aagcagaaat cctccgtggt gctgtgcctg tttatggacg
    22141 gcgttagccg gccatgatgt ctcacccccc gtatctaaca ggggggtaca aaaacacaaa
    22201 aaataagcaa gcaacgataa ggaatggctg tcctatcaag gataataagc aatttgtgta
    22261 gatgttaact gatttgaaaa agttaacacc ttaaatttgg aggtgagaac ttggcacaaa
    22321 ggaatttaga ttatcggcta ttaaaagacc ggcgtaatga atatggcgtt tcacaaaata
    22381 aattagctac gacttgtgga cttagtcgcc cgtacttaaa tcagatagaa aatggtggcg
    22441 taaccgcatc gacaaaaacc atgaggaaaa tttttgacca actggaaagt ttcaatcccg
    22501 agttaccttt aacgttactg tttgactatg taaggattcg ctttcccaca acggatgcga
    22561 ggaaaatcat tcaagagatt ctccatttga aatttgatta tatgctccac gaagattacg
    22621 ccttttactc ctatcaagaa caatatgtta tgggagatat tgtggtgatg ttgtcacatg
    22681 aagaagataa aggcgtcctt ttagaattaa agggtcgtgg ttgtcggcag tttgaaactt
    22741 ttttactcgc ccaaaagcgt agctggtatg actttttcga agattgtcta aaagccggtg
    22801 gcgtgatgaa acgcttagac ctggcaatca atgatcgagt tggcctgtta gatattcctg
    22861 atttaacgaa aaaatgtcag aaggaagaat gtatctcctt gtttcgtacc ttcaaaagct
    22921 atcgttccgg ggaactgttg aaacctgatg ataaagatgg tatgggcaat actttgtata
    22981 ttggcagtct taagagtgag gtctatttct gtttgtacga aaaagactat gagcaatata
    23041 tcaagttagg gattccttta gaccagaccg aaacgaaaaa tcgttttgaa atccgactga
    23101 aaaatgatcg agcttatcat gcaattcaag atttgttaaa aggtcgcagt attgaaagta
    23161 ccacattttc cattattaac cggtacttgc gatttgcgga taaggtggaa ggcaaaaggc
    23221 gaactaactg gcccttgaat gaacaatggg ggcgcttcat tggacggaat cagaaggaaa
    23281 ttcaattaac ttctgaaccg aagccttata ccattgaacg aacgttgaac tggcttggac
    23341 gacaagtcgc ccctacgtgg aagatggcca aggagttgga tcggttgaat cagacaacgt
    23401 acattcagga tatggtaaat aatactcgac tatcagaccg gcacaaaaag attttggagc
    23461 aacaaagtat ggcaattgaa aatttgatta tatgaaaaga ggaatcgtga tggaaattgt
    23521 gaaagatatt ttattggtgt ttggtggcag tatgcttggt gttactgtga tgtgcttgat
    23581 gcatgcaagt gcagcggcgg accgagcaat ggaaaagaaa ggaaagtgat gaaatgaatt
    23641 tcggtcaaaa ttt
//
LOCUS       DAFLVO010000043        23523 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.043, whole genome shotgun sequence.
ACCESSION   DAFLVO010000043 DAFLVO010000000
VERSION     DAFLVO010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23523
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.043"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            118..1779
                     /locus_tag="L1U99_001762"
     CDS             118..1779
                     /locus_tag="L1U99_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1212301.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(1849..2211)
                     /locus_tag="L1U99_001763"
     CDS             complement(1849..2211)
                     /locus_tag="L1U99_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HBN1212302.1"
                     /translation="MKEQSNEKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFL
                     WSLPFLIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLII
                     AGILIALSAIFMLFSLLG"
     gene            2279..3220
                     /locus_tag="L1U99_001764"
     CDS             2279..3220
                     /locus_tag="L1U99_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1212303.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3221..4264
                     /locus_tag="L1U99_001765"
     CDS             3221..4264
                     /locus_tag="L1U99_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1212304.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4270..5340
                     /locus_tag="L1U99_001766"
     CDS             4270..5340
                     /locus_tag="L1U99_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1212305.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5330..6283
                     /locus_tag="L1U99_001767"
     CDS             5330..6283
                     /locus_tag="L1U99_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1212306.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6295..7305
                     /locus_tag="L1U99_001768"
     CDS             6295..7305
                     /locus_tag="L1U99_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1212307.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7590..8411)
                     /locus_tag="L1U99_001769"
     CDS             complement(7590..8411)
                     /locus_tag="L1U99_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBN1212308.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8508..8786)
                     /locus_tag="L1U99_001770"
     CDS             complement(8508..8786)
                     /locus_tag="L1U99_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212309.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9054..11063
                     /gene="metG"
                     /locus_tag="L1U99_001771"
     CDS             9054..11063
                     /gene="metG"
                     /locus_tag="L1U99_001771"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBN1212310.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11542..12129)
                     /locus_tag="L1U99_001772"
     CDS             complement(11542..12129)
                     /locus_tag="L1U99_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212311.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12304..13626
                     /locus_tag="L1U99_001773"
     CDS             12304..13626
                     /locus_tag="L1U99_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1212312.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13781..14557
                     /locus_tag="L1U99_001774"
     CDS             13781..14557
                     /locus_tag="L1U99_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBN1212313.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14550..15119
                     /gene="rnmV"
                     /locus_tag="L1U99_001775"
     CDS             14550..15119
                     /gene="rnmV"
                     /locus_tag="L1U99_001775"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBN1212314.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15112..15996
                     /gene="rsmA"
                     /locus_tag="L1U99_001776"
     CDS             15112..15996
                     /gene="rsmA"
                     /locus_tag="L1U99_001776"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBN1212315.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16447..17076
                     /locus_tag="L1U99_001777"
     CDS             16447..17076
                     /locus_tag="L1U99_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212316.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17200..18309)
                     /gene="ugpC"
                     /locus_tag="L1U99_001778"
     CDS             complement(17200..18309)
                     /gene="ugpC"
                     /locus_tag="L1U99_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBN1212317.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18518..18940
                     /gene="mgsA"
                     /locus_tag="L1U99_001779"
     CDS             18518..18940
                     /gene="mgsA"
                     /locus_tag="L1U99_001779"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBN1212318.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            19263..19799
                     /locus_tag="L1U99_001780"
     CDS             19263..19799
                     /locus_tag="L1U99_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBN1212319.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(19839..21602)
                     /locus_tag="L1U99_001781"
     CDS             complement(19839..21602)
                     /locus_tag="L1U99_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1212320.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21605..23320)
                     /locus_tag="L1U99_001782"
     CDS             complement(21605..23320)
                     /locus_tag="L1U99_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1212321.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
BASE COUNT         7586 a         4303 c         4781 g         6853 t
ORIGIN      
        1 ttattttatg aaaaagacaa aaaaaagtgt tgatttttta ataattattc attaaactct
       61 taaacaactt cagaaaatat taattattct gaaaattcca ataaaggggt acgtaaaatg
      121 aaaaagaaat ttacatttgg tttggttgcg gtatgcggcc ttgtacttgc tggatgttat
      181 ggcggcagtt cagccacaag cagtagttca gcaaaaagcg gttcagcaga tggaggaggc
      241 gtatttaact tagtcgtgcc tcaagaaatg cctacagctg acttatcagt tgcaacagat
      301 acaatcagtt ttacagcatt gaataacgtt tatgaaggaa tttaccgtct tgatgaagac
      361 agcaaaccac agccggcagg agctagcgag ttggcagaag tcagtgaaga cggattaact
      421 tacaaaatca aattacgaga agacgcaaaa tggtcaaatg gtgatcctgt tacagcagcg
      481 gattacgttt atggctggca acgaacagta gacccagcta cagcttctga atatgcttac
      541 ctgtatgcgc cagttgaaaa tgcagaagac attacagctg gaaagaaaga taaatcagaa
      601 ctagggatca aagcagttgg tgactatgaa ttagaaatca aattgacgaa acaaacacca
      661 tatttccaat atctgcttgc tttcccatca tttttcccac aaaaacaatc cgtagtggaa
      721 gaaaatgggg atgcctatgc atctgcaagt gataaagctg tttataatgg accattcaca
      781 ttagaagatt ttgatggacc aggaacagat acagaatgga cttataagaa aaatgatcat
      841 tactgggaca aagatacagt aaaactttct gaaatcaaag tcagtgtagt aaaagaatct
      901 tctactgcat tgaacttatt caaagatggc caagcagatg acgtgatctt gtctggtgag
      961 ttagcacagc aaaacgcaaa cgatccagct tatacttctg ttaaagaagc gcggacaagc
     1021 tatatcgaat tcaatcaacg tgaaaagaat tcaccattca acaatgtgaa cctaagaaaa
     1081 gctatttctt attctatcga tcgtgaagct ttagtaaaac aagtactagg tgacggatca
     1141 gttgtctcta caggattgat cccatcagat atggtaaaaa gtccaacaac gaacgaagac
     1201 tttgcaaaag aagctggaaa attagtttct tatgacaaag ataaagcaaa agaatattgg
     1261 gaaaaagcga aaaaagaatt gggcgttgat tctttagaat ttgatttgat ggcttctgat
     1321 gatgattcat cgaaaaaagt aatcgaatat gttcaaaact caatccaaga aaacttggat
     1381 ggcgtaacag tcaaaccaac acctgttcca ttctctgtac gtcttgaccg ctcaacttcg
     1441 ggtgattttg acgcagtact aggcggatgg gctgctgact atgcagaccc aagcagcttt
     1501 actgatttgt ttgtcacagg taattcatac aaccgtggtc gctggagcaa tgcagaatat
     1561 gacgaagcag ttaaagcagc ttcatcaaca gacgctggcg atgaacaagc ccgttgggat
     1621 gatttccaaa aagcaatcaa gatcatctct gatgatatgg gtgtcgttcc ggtgtaccaa
     1681 aaagcagaag gtcacctagt gaatgaaaaa atcaaaggta tcgttcacca tgcggcaggc
     1741 gcttcatggg attacaaatg gacatacgtt gaagaataat cgttaatacc gtgagcatga
     1801 gaaaaaacga ggctgcggca aatgtcgcaa cctcgttctc atattcactt atcctaacaa
     1861 agaaaaaagc atgaaaatag cagaaagagc aattagtatt ccggcaatga tcagccaaaa
     1921 gctgtacata ccgtagctgg cagacgagag cgtggaaaat tctggttttt tctttcggtt
     1981 ccttgttcgt gcaagatgga ccgatcgctg aaaatgatcg aagaaacccg aagaaaagac
     2041 ccataaaaaa ccgccgataa tcagaaacgg caatgaccat aagaatagat cattagataa
     2101 ttgaatgagt gtaaaggaat ggttgatgag attttttatt aaaataacca gaatcagtag
     2161 aaaagctact gcgtagggga tagatttttt ttcatttgat tgctccttta tttttggttc
     2221 attatctaat aatgtagcga aacatctgtc agaagtcaaa agctaggggg aaacattagt
     2281 gaatagttat atcaaatatg tattaaaacg tgtctttttc atgatcatca cgctttggtt
     2341 aattgcaaca atcacctttt tcttgatgca attgctgccg ggcacgccat atacgaatca
     2401 ggaacgtttg agtcctgaaa caatcgagat gctaaataaa caagtcggtt tggataaacc
     2461 agttatcgta caatatggga tttatctttc taatttgctt caaggagatt ttggaatttc
     2521 cttccaattt aaaaaccagc cagtcgcaca tttgttagct ggaagaatcg gaccatcctt
     2581 gcagttaggg ttacaggcaa ttatctttgg aacagtccta gggacgattt taggaacgat
     2641 ctctgccatg aagcaaaata catgggcaga tacatcttct acactcgtag cgatattagg
     2701 tcgttccatt ccaaactttg tatttgctgt tttattacaa tatatctttg caatcaaatt
     2761 acaagttttg ccaatcgcaa aatgggatgg ctttgtgtac acaatcttac caacaattgc
     2821 gttggccatg tcgccgcttg ctgactctgc tcggtttatc cgtacggaaa tggtggaagt
     2881 actgcatagt gattatgtgg aattagcaaa agcaaaagga ttgagccgtt gggaaatcgc
     2941 ctttaaacat ggtcttcgaa atagtttgat tccattgatg actttattag gaccgttagc
     3001 tgtagcattg atgaccggat cactggtggt agaaaatatc tttgctattc ctggtatcgg
     3061 ggaacaattc gttaagtcaa tcacaacaaa tgattatcct acgatcatgg ctgtaacgat
     3121 cctttactca tttatgctga tttttgttat tttgatcgtg gatctattgt acggtctagt
     3181 tgatccaaga attcgtgttt cagaagggag ccgaggataa atggaaatga taccaaagcg
     3241 ttatgaaaca gttgcagata tccctgcgga tgaatttctt ccattacaaa aaaataccga
     3301 agaagaacgt gaacagatta ctgcaccttc tttgaatttt atccaagatt catggcgccg
     3361 tttaaagaaa aacaaagctg ccgttatttc aatggtttta ctattggtca tcattttgat
     3421 ctctgtgatc acaatctttg tttctcctca tgatccaact gcccaaaacg tggcttatat
     3481 caatttgcct cctcgtattc cgggaatcaa tatcgatgga ttgaatggaa aagcaatggt
     3541 tggtggtgaa cttgttgata aatatgctca agcaaacgtc ccttcaaacg taaatttctt
     3601 tttaggaaca gacggtttgg gacgtgatgt attaagccgc ttatttatgg gaatgagaat
     3661 ctcgttgctg atcgcattta ttgctgcatt actagatgta acgattggtg tagcttacgg
     3721 gttggtttct ggtttgttag gcggacgtgt cgataacgtg atgcaacgtt ttttggaaat
     3781 cttatcagga attccaaacc tcgttgtcat gattttgatg ttggtcgttt ttgaaccagg
     3841 aattttttca atcgtggctg ctatggccat cacaaactgg ataccaatgg cacgtatcgt
     3901 tcgtgcacaa acaatgaaat taaaagatca agaatatgtt ttagctggat tgacattagg
     3961 tgaatcaaga atgaaaattg cattcaaaca tattttgccg aatatctcta gtgtcattat
     4021 tattcaaatg atgtttagta ttccatctgc tattttcttc gaagcctttt taagctttat
     4081 cggtttaggt cttacgcctc cgtcagcttc attaggaacg atgttgagcg aagggtacaa
     4141 gacattcctg tatctgcctt atctattatg gattccggca gtaactttat cggttatcat
     4201 gattggcttt aacttacttg ctgatggatt gcgtgatgcc tttgatccta aaatgaaaga
     4261 gtgaagacga tgacgaaaat tttagaagtg aaagacttag aaatctcttt tgatacgtat
     4321 gctggaaagg tacgagcgat tcgcggtgtc aattttcatt tgaataaagg agaaacattg
     4381 gcgatcgttg gggaatctgg aagtggaaaa tcagtgacga ccagaagcat catgcgcttg
     4441 ctgtcaagca acgccaatat agatgctggt caaatcctct ttaaaggtaa cgatatcgtt
     4501 ggaaaatcag aaagagagat gcaaaaaatc cgtggtaaag aaatagcgat gattttccaa
     4561 gatccaatga cctctttaga tccgacgatg cccattggga agcaagtcgc tgagtccctt
     4621 agaaagcata ataaagtttc aaaaaaagag ggacaaaaag ctgcattaga attgcttaaa
     4681 ttagttggaa tacccgaagc tgagaaacgt atcaacagtt atccgcatca gttctcagga
     4741 ggtcagcgtc aacggatcgt gatcgcgatt gcactggtat gttatccgga aatcctgatt
     4801 gctgatgaac ctacaacagc gcttgatgtg actattcaag cacagatttt ggagctgctg
     4861 aaagaaattc agacaaaaat cgatacatca attatcttta tcactcatga ccttggtgta
     4921 gtagcgaatg tcgctgatcg tgtcgctgtc atgtatggag gaagaatcgt tgaagttgga
     4981 acatcggaag aaattttcta caacccgcaa catccctata cttggggact gcttggttca
     5041 atgccgacat tagatagtgc gaacgatcga ttgtatgcta ttcctggttc tccaccggat
     5101 ttattgaacc cgccaaaagg agacgcattc tatccaagaa atgaattcgc gatgaaaatc
     5161 gatgcagaac aagaaccacc attttttgaa ctatcaaaaa cacacaaggc agcaacttgg
     5221 ctacttgctc cgcaggcacc caaagtgaca ccgccagaag aaatccaacg tcgctgggct
     5281 atctttaaag agaaacaaaa acatacttac ggtcaaggag gaattgctga tgccaaataa
     5341 actacttgaa gttaaaggat tgaaacagta tttcaatgta ggaaaaaaga atgaagtaca
     5401 tgctgtaaat gacatcagct ttcacattta tgaaggagaa acattcggtt tagttggaga
     5461 atctggaagc ggaaaatcca ctactggccg tacgatcatt cgcttgaatg aacctactga
     5521 tggtgagata ttattcgacg gtcaagatat aacgaagatc aaagataaaa aaggtttgac
     5581 gaaattccgg catgatgttc agatgatctt tcaagatcca tacgcttcgt tgaatcctcg
     5641 tatgaaagtc agagatatca ttgccgaagg aattgatgtt aatggactag ctaaatcatc
     5701 tgaagagcgt gcaaaaaaag tcgatgatct attgagaact gttggattga atccaagcca
     5761 cggtactcgt tatcctcatg aattttcagg tgggcaacgc cagcgtattg gtattgcacg
     5821 agcattggca gtaaaaccgc gttttatcat ttgtgatgaa ccaatttctg cactagatgt
     5881 gtcgatccaa gcccaagtgg tcaatttgtt gcaagatctc caaaaagaac atcaattgac
     5941 ctatctattt attgcacatg atttgtcgat ggttaaacat attagtgacc gaatcggtgt
     6001 aatgcataac ggcttgttat tagagatggg aacaagtgat gaaatctata atcacggtgt
     6061 tcatccttat acagaaagtt tgttatctgc tattcctcta ccagatccag accatgagag
     6121 aaaacgcaga agaatcaaat atcaacctga accagatgac ggacaagtac gtcaacttcg
     6181 tgaaatcgca ccagaacatt ttgtctatgc aactgagcag gaagtcccat attacgcaaa
     6241 aaaactaaaa cgacaaaagg aatctcttct ggttgctaac taggagggac atagatgcta
     6301 aaagctttta aattccgtat gtatccgaca gaagaacaaa aacagcaatt gattcgtact
     6361 tttggatgtg ctcgatttac ctataaccat ttgctgaaaa agcggcagaa aagttggcaa
     6421 caaacaggag tagccaattt ttcgctcaca cccgctacat taaaaaaaga atacccattc
     6481 ttaaaagaag tagacagtct tgctttagca aatgcacagc ttaatttgga tcgggctttt
     6541 cgcaattatt tcaagggacg tgccagcttc ccaaagctta aaacgaaaaa aagtatgtgg
     6601 caatcttata cgaccaacaa ccaaacccgt acgatctatc tggaaaatgg ctacttaaag
     6661 ttaccaaaac aaaaagaact aatcaagata aatcagcatc ggccagttga aggatcgatt
     6721 cgctccgcta cgatttctgc tcgatataat gaagaatttt atgtcgcact actttgtgat
     6781 gtttcgccag taaaaaaaga atctttagct aaatggatcg ggatcgccta tcatccgaag
     6841 acattgatcc aaacatctcg acctctagaa gtaactttac caaaatttca ccagacagaa
     6901 gaaaagctgc aacatgcaca gcggaaattg aatgtgaaag tccgctccgc tcaccataga
     6961 aagatcaggt tagatcaggc aagcaattat cagaaacaaa agagaaaagt aatggatctt
     7021 tatctgaaac aaaagaacca gcgagaagat tatcttgaac aattatctgg gaaattggtc
     7081 aaacaatatg actacttatt tgtagaatct tttccaaaag aagaggcaca tgctgatttt
     7141 tctattcacg actggcataa attaataaca aaattgcgtt ataagtccca atggtataat
     7201 aaaaaatttc ttttgatcaa taccgacgga gcagaagaaa gcaattccgt aagaaagagc
     7261 caagtagtag aaaaaatggg cagacattcg gttatcaagg gataaaaaat gaatgaaact
     7321 gataggagcg ttagggttag ccttgttaat aaaaagtctt aatgactttt gtttctagga
     7381 atttttcttt tgaagaaaag ctcactaatt atgacaaacc aataaaacaa tagcagaaaa
     7441 agttcgtacg agctttttct gctattgtta attttttatt cagaaagttt acgaatacat
     7501 caaaattctg aaacaaaaaa cgtaactcac aaagagttgt ttttgcgttt tttcttgaat
     7561 gattaggtct gaatcttttg ctcacaacct tattcatggt gccccggctt gagctgatag
     7621 atttttgaag gacggccgat tcctacagga cgttcaccga tctcatcgaa atattggagc
     7681 atagctttct taaaattgga atgatcgatc gttttataat cgatccctaa gaatttagca
     7741 aatacttttc gagcttccgt aatcgtgaaa tctttaccta aaacttgtag aacttgcggc
     7801 tcgtgttcca ttttattgac tacacggttg aatgctttca agatgatttg actatggtca
     7861 aaagccaaag tatctttgcc agaagactct ccagtgacta aatcaagcga gatagccact
     7921 tctccgctag ataaatggat cttgttacta tgacgttcta gtgtgaacca gcgtacttcc
     7981 ttggcatcat ctccggcgat tagcggttct tctccaataa aggctaagta gctgactgtg
     8041 acgacccagc ctcgcggatc tcgattaggc gtactgaatg tatgcagttg ctcaatattt
     8101 tcttttgaaa taaccacacc agtttcttcc tttgtttctc ttaagacgct ttctccagtt
     8161 gactcatcct tttggacaaa gccaccaggc aatgcccatg aatttcgata aggatgccct
     8221 tttctttgga tcaacaaaac tttcagctga tcttcttctt tgttatagca catcagtacg
     8281 atatcgacag tcaaagaggg cttgtcatat tctggacgtt cctgtttttg ataccagtta
     8341 agaaattctt cttcacttgc tttatgttca taatataatt tttcttcttc tttagaagca
     8401 aaacggttca tctgaccacc tccattgaca gtaaaagtac tttttacctt attgtagcag
     8461 actctgaaaa aaaaccaagg atttacttga aaaatctagg ttatcattta aatatgaaaa
     8521 ataaatggaa gtatgagatt gaataaaaag aaaagcagat aaaacggcaa tactttatac
     8581 cgctcttcac gaatggcaaa gaagccacaa ataacgatat atacgtcaat gataaaacgc
     8641 aaaatccaag ctgctgtcat aaaactgttc aaatgcccat ggaggttaaa ataaccatac
     8701 atacgaatat aaaaatagct gaatattaaa tgtgctaatg aaagaaaagc aatactaagt
     8761 gtaaaaaaaa gatgtttctt ctgcatgatt gttccagtcc cttactaaga tagatagtct
     8821 ttattatacc acgtgtgagg ggagaaataa aaagccgttt tttagtagat atgaaacaaa
     8881 acaaaaaccc gcatttattc aacctattca tccttttaaa ggatagattg aacgtagata
     8941 gaagtcgttt atccagtctt tttcattttg aaaaaaagct aacagcatgc tttttttatg
     9001 gtatactagc aaggaaacga attcgcatca tgcgataaag gaggaagagc cccgtggcag
     9061 aaaaggaaac tttttatatc actacgccaa tctattatcc aagcggcaaa cttcatatcg
     9121 gcaactcgta tactacgatt gcatgtgacg caattgctcg ttataaacgg ttgatgggct
     9181 ttgatgtgtt ttatctcact ggagtggatg aacatggtca aaaaatcgaa acaaaagcag
     9241 aagaactagg tgtaaaaccg caagaatatg tagataaaat ggcggctgat gtcaagaaat
     9301 tatggaaaac gcttgatatc agttatgata aattcattcg cacgacagat gattaccata
     9361 aagcagctgt tcaaaaaata tttgatcgtt tattagaaca gggagatatt tacttaggtg
     9421 aatatgaagg ctggtactct gtttctgacg aagaattctt tacagaaaca caacttgcag
     9481 aagtgtacaa agatgacgaa ggtaacgtga tcggtggtaa agcgccaagt ggacacgaag
     9541 tagaattggt aaaagaagaa tcatacttct tccgcatgag caaatacgca gaccgtctat
     9601 tggaatacta tgaagaacat cccgaattca tccagccaga atctcgtaaa aacgaaatga
     9661 tcaacaactt tatcaaacca ggattagagg atcttgcagt ttcacgaaca acttttactt
     9721 ggggagtacc agtcaagagt gatccgaaac atgtggtgta tgtatggatc gatgcattat
     9781 ccaattatat tactgcacta ggatatggct ccgaagatga aagtctattc gaaaaatact
     9841 ggcctgcaga tgttcagatg gtcggtaaag aaatcgttcg ctttcatacg atctattggc
     9901 caatcatgct gatggccctt gatttgcctc tacctaaaaa agtatttggg catggctggc
     9961 tattgatgaa agacggaaaa atgtctaaat caaaaggaaa tgtcgtttat cctgaaatgc
    10021 ttgtggaacg ttatggttta gatgcactcc gttattattt gcttcgtgct gttccgtttg
    10081 ggtcagatgg tgtctttacg ccagaagatt ttgtttcccg tgtcaattat gatctggcaa
    10141 atgatctagg gaacttattg aatcgaacga ttgctatgat caacaaatat tgtgatggac
    10201 tcgttcctga ctatgcctca cttgtcactc catttgatag tgaactgtct acgacggctg
    10261 ctaacgttgt cggacgttac catgatgcaa tggaaaaaat ggaattcaat acagcattgg
    10321 ctgaaatctg ggtgctgatt tctcgtgcaa acaaatacat tgatgaaaca gaaccatggg
    10381 tattagcaaa agacgaagaa aagaaagctg aattgaatag tgtcatgatc catttagctg
    10441 aatctttgcg tatcgcagcg atattacttc agccaatcat gacagaaacg ccagagaaga
    10501 tcttcaatca actaggattg gactctgaaa caatgaatct tgaaggatta cactttggcg
    10561 aatttccttc aggaacaaaa gtagttgcaa aaggtacacc aatcttccca cgtttagata
    10621 tggaagaaga agttgctttt attcaagaaa aaatgtctga aggtactcaa acaaacgaag
    10681 atacagtcaa atgggatcca gaagaaacag aacttgtttc aacgaaagaa aaacaaatca
    10741 aatttgatgt atttgaaaaa gtagaactaa aagtagcaga agtcatcaac tgtcaaaaag
    10801 tagaaggggc agataagttg ctgcaattcc gactagatgc tggagacagc caagaccgtc
    10861 aaatcttgtc aggaatcgct gaattttatc ctgatccaag cgaattgatc gggaaaaaag
    10921 tcgtcattgt agcaaatctg aaaccacgaa agatgcgtgg acaaatcagt caaggaatga
    10981 tcctttctgc agaagcacca gatggctctt tacaagtaat cgaagcacca aaatccatgc
    11041 caaatggctc agaaatcgca tagaaattca aagggggtat gacactagtt gtgtcatacc
    11101 ccctttttcc gaaatttgag aagcaatttt cgtaaattcc ttcttattac ttgaagccaa
    11161 tcatataata cagaaacaga gaactatcca aaataaatcc tagaaaaaga agtacgagct
    11221 tcgctgattt ttgttaattt agaataatac taataggaat cgtaaaaaca gaaaaaaagc
    11281 ataatgataa agggtcgggc agattttaat tgattcatct ggtactcttt tttattgtcc
    11341 ttacattcat aaagtttgaa tgcaatgact ttattacatc tatatttata tctaacagta
    11401 gcgttgatgt gttaattata agttctatca ctttatgttc aattagtttg tgctcttata
    11461 tgtgtgattg aaaatataga taaaaaaaca atcatcggct ttgacttcga tgattgtttt
    11521 ctttattttg taaaaatcct atcacttgat tttatggtaa ccttttattt ttgtcttcaa
    11581 acggcttggt aagagagcag taagcagtgc aaatgggatc gaaaagacat accagaaaat
    11641 cgtacgtccg ataccataat gttgatagag ctttgtcaac atcacgtgta acaagatcaa
    11701 ccctaaaagc aaggagccag ctataaacca atgattatcc caatgcatga cttcactaag
    11761 tgccatcact ccaaaaggat agaaataaaa atagatcccg actaaggtca tccgccagtt
    11821 ctttgtaaat gttccgatat tcaataaaaa gaaaatcgct gaaagcaaaa taccgatagg
    11881 cggaaaaagc ccaaccaaaa aggaatacaa catcccccac aagatcatca caggaccttt
    11941 gatcaatgca acgattgcga tgaacaaagt cagcaatatt agtttttgtg ataacgttgc
    12001 aacagtcatt aatccaaata aaattaatgt gaaccaatgc caatgggact gctgttgttc
    12061 tttacgggaa aaatcgaccc ggttggataa ataatctgct aatttcggat aagaacgctt
    12121 aaaatccata aactgttcct ccttcgtgga aaaggtaggt ttagtatacg aaaaataaaa
    12181 aagaaataca tccgtcttaa gagggagttt ttcactgaaa gtggagaaaa aagaatggta
    12241 aattaaaata ttctcagtta tactgaaaat tataccaaat ttcaaagaag aaagaggatg
    12301 ggaatgaaag gcaaactaaa acgagaaatc aatctgtttg gcgcattagc taccgttatg
    12361 ggaaccgtga tcggtgcagg cgtcttcttc aaaactgctg ctgttactgc tagtactcag
    12421 tctacaagtt tgacattgct agcttggctt ttgggtggtt tcttaacgat ctgtgctgga
    12481 ttgacagtgg ctgaattagc tacagcaatc ccggaaactg gtggagctgt aaaatatatt
    12541 gaagctgcgt atggaaaatt gcccagcttt ttattaggat gggcgcaaag cttgatttac
    12601 tttcctgcta atattgctgc attatcgatt atctttgcga cacaattgac gaacttatta
    12661 caattatcta ccgattatct tttgttgatt gcagtgatca ccgctgtttc tgtgacaggg
    12721 ttgaatttgt tagggacaaa agtcggtgct tctgtacaat cagtgacgtt gattgttaaa
    12781 ttaataccaa ttgctgtgat tgtcatatgg ggattattga ccccaggaca aggaactgtc
    12841 cagttatttc caatcgaagc tggaaaagat gttacttttg tcgaaggatt gagcagtgcg
    12901 ttgttagcaa cgttgtttgc ttatgacggc tggttaggtg tcggtgcaat ggcaggggaa
    12961 atgaaacggc cggaaaaaga tttgcctaaa gcaattattc ttggtttgag ttttgtaaca
    13021 gtcgtttatc tattgatcaa ttttgttttt ttgaaaactt tgccgattga tcatcttgcc
    13081 ggtaatttga atgcagcttc tgaagcatca gacgtcattt ttggaggaat cggtggaaag
    13141 ctggtcacta ttgggatctt gatctcggta tacggtgcat tgaacggtta tacactaact
    13201 gggatccgcg tgccttatgc gatggcttta gaagacgagc tacctttcag taaacagctg
    13261 acaaagcttt caaagaagtt tacggttcct tatgttcctg cggttttcca gttagcagta
    13321 gcttgtatta tgatgagcct tggttctttc gactttttaa cagacatgtt gatttttgtg
    13381 atgtggctat tcagtttact gatttttatc ggtgtcttta ttttaagaaa aaaagcgccg
    13441 gaattgccac gtccatataa agtaccactt tatccaatcg ttccgattat tgcgattctc
    13501 ggtgctattt tcattttagg tatgacgatg atgacgcaaa cgaaattagc attgatcggt
    13561 ataggtgtta ccttgatagg tatcccagtc tattatcaaa aaaagaaaaa acgctcagaa
    13621 gagtaaaata tttcaacaac agacagaaaa agtacgaact aggtcctcta gatcttcgtg
    13681 ctttttctat ttcaataaaa caagttcttc tattttgatt tttgctactt ctgcaagtag
    13741 tgcttatgtg ctaaagtaag aatgaaaagg agagataaac atgatatttg attctcatac
    13801 ccatttaaat gctgaacagt tcaatgaaga tattccagaa acgattcagc gagcacaaga
    13861 aatgggggta acgaaaatgg cggtcgtggg cttcgatacg ccaacgattg aaaagtcttt
    13921 gcaattaagc catgactatc caaatatata cagtattatc ggctggcatc cgacagaggc
    13981 tggcagttat acgaaagaaa tcgaaaataa attacaagaa caattgactt taccaaaggt
    14041 tgtagcatta ggggaaattg gcttggatta tcattggatg gaagacccga aagaagtcca
    14101 agataaagta tttcgcagac agattgctat cgcaaaagaa atgaacctac caatcagtat
    14161 tcatactaga gaagcacttg aagacacgta tcaaatccta aaagaagaag atgttcgaga
    14221 tatcggtgga atcatgcata gtttcagtgg tgattatgaa tgggcaaaac gatttcttga
    14281 cttagggatg catatttcat ttagcggtgt cgtcactttc aaaaaagcat tagacgtcca
    14341 agaggctgca gcaaatgtac caatcgaacg attacttgtg gaaacagatg ccccttatct
    14401 ggcaccagtt ccttttagag gaaagcgaaa tgaaccaggc tatactcgtt atacagtaga
    14461 aaagattgct gaacttcgga atcttccgac agaagaagtg gctgcccaaa catggacaaa
    14521 tgcgcaccga ttatttggtc taagcgaaca tggataagat gaagatccaa gagattatag
    14581 tcgttgaagg aaaagacgat acaagaaggc tgcgggaagt agttgatgca gatacgatag
    14641 aaacaatagg gtctgcaatc aatgaagaga tcctgatgca aattgaacat gcccaagaga
    14701 ctcgtggagt gatcgttttt accgatcctg atttttcagg agaaaaaata agaaaaatca
    14761 ttatggaagc tgttcctcag gcaaaacatg cttttttgcc gcgcacacaa gctaaaccaa
    14821 agaaaaaggg aagccttggt gtcgagcatg caagtgatgc tgctatttta gaagcattga
    14881 aaaaggtcgt gacgccagac atttcccaaa cggctgtttc tgaaatcact agacaagacc
    14941 ttttagacta tggtttaata gctggggcac aagcaaaaga aaaacgagaa aaactaggtg
    15001 acgagttgcg catcggttac acgaacggca aacaattgga aaaacgtttg aagatgtttc
    15061 gtattacgcc gaaagaactc gcccaagcaa tgaaaatagt ggaggaacaa catgagtgaa
    15121 tatcgtgaaa ttgcgacacc ctctagaaca aaagagattt tattgaaaca tggtttttca
    15181 tttaaaaaaa gtttaggaca aaattttctg actgaaccaa atattttaag gaaaatcgta
    15241 gaaactgcgc aaatagatga acatacgaac gtgatcgaag ttggaccagg aatcggtgca
    15301 ttgacggaac aattagccaa gcatgcaaaa caagtcgtag catttgagat cgatgatcgt
    15361 ttgatccctg tattggctga tacgatgcaa ccctatgaca atgtgactat tgtacatcaa
    15421 gatattttaa agaccgattt gtcaacagct gttagagaaa catttcatga ggagcttccg
    15481 ttaaaagtcg tagcgaattt accttactat attacgacac cgatcatgat gcattttctt
    15541 gaatcagatt tggttgtgga tgaactagtc gtcatgatgc aaaaagaagt agctgatcgt
    15601 atctctgctg aaccaggaac gaaagcttat ggttcattat cgattgctgt tcaatattat
    15661 atggaagcca gtttagcatt catcgtacca aaaacagtat ttgtccctca gccaaatgta
    15721 gattcagcga ttttgaaact gacaagaaga gatataccgg cagtcgaagt gacagacgaa
    15781 aaagcatttt tccgattgac aaaagcggca tttcagcaaa gaagaaaaac gctttggaat
    15841 aacttgcagc attcgtatgg caaagatgac cagacaaaag catggttagc aaaaagcttg
    15901 gaaacagctg gaatcgatcc aaaacgtcgt ggggagactt tgtcattaca agaattcgcc
    15961 gcattaagca atgcgatgtc agaaaatatg cagtaaaaaa agaggttgtg acagaagttg
    16021 tgaaaaagct gtcctgcatc aagtaataag aacagccaaa caaaaatagt tcctcatgtt
    16081 tttcgtttgt ttgggcttat taccgcagat gcaagctttt gaacaccgtt taagaaagag
    16141 gttgtgggcc tgccgtttaa ctctaagtca caaggaacaa tttcaaaaaa cagcttctca
    16201 tgtttttgag ttagttggtc ttattacttg atgcaagctt ttgaccacta ttatgccgaa
    16261 caaggagatg tgacacaaat tttgtcacat ctcctatttt tgtttcttga tcaaaaaatt
    16321 cttatacttg atactcacac tcattttgta tggatttaga aaagaatatg tgtcttgaca
    16381 gttattagta agtgagttat actaagtcga catttatgtg tcaagacata ttaggagaga
    16441 gaaaaaatga gaaaaaattc agttcgaaaa ctaacgattt ctgctttatt gattgggatg
    16501 ggggtcatta tcccaatggt catgcctaaa atcatgattc caccagcttc ctttactttg
    16561 gcgtctcatg tgccattatt tattgcgatg ttttttacac caggagttgc agtggctgtt
    16621 gcgctaggta cgacatttgg tttcttttta acaacgccgg ttatcatcgc attgcgagca
    16681 ttgtcacatc ttgtgtttgc gttgattggg gcttggtact tgcaaaagca tccgagtatc
    16741 gttttaaaaa atggacagtt tacttttgct aattggcgtt tccaagggtt caattttgtg
    16801 atcggtgtga ttcattcttt agcagaaatg ctagtagtca gcatctttta ctttattggt
    16861 aatatgcctg aaacatatta ttctcaagga tatttttata cagtattcat cttgatgggg
    16921 attggtgggc ttatccacag tttagttgat tataatattg cttattttat agcaggaaca
    16981 ctcagcaaat attttgatat ccccgtattt acggcagcaa aaaaagaaaa tcggaaagag
    17041 tcgattcaag ggtacgcgaa gaaaacgaca tattagacat gatctctcaa aaaaaaaact
    17101 ctcatctagt aatggataat aaatcctcta agatgagagt tttttgtcct aaaaagagct
    17161 gcaccaacat cttctggcac agctctaaca gggggcaatt tatggaagtt tgatgacttg
    17221 ttctgtttct ttatcaaaga agtggccttt gctgatgttg aaggcaaggt cgactatttc
    17281 gcctggttta tggaaatctc ttgcatctac ttttgagatg aactcagtag aaccagtttt
    17341 tgtgtaaagc atcgtttcag ctccaagtaa ttcggaaacg acaacttctg atttcactac
    17401 ggcttcaggt gaagcttcaa gggctacttg ttcactgtgg atgtcttctg gacgaatacc
    17461 gaagataact tcttttcctt cataaccttt ttcaactaat actttgtttt ttccttcagg
    17521 aatacgaagc ttaagcccat gtccatctgt gataacacca tttttcaatg tcacattaaa
    17581 gaagttcatg gcaggagatc caataaagcc ggcaacgaac atattgacgg gtgtatcata
    17641 aacttctttc ggtgtaccga tttgttggat aaatccgtct ttcatgataa cgattcggtc
    17701 agccatagtc attgcttctg tctgatcgtg agtaacatag atggtcgttg tttcaagacg
    17761 ctggtgaagt ttggcaatct cagcacgcat ggctacacgt aatttagcat ctaaatttga
    17821 taatggctca tccattaaga agacttttgc atcccgaacg attgcccgtc ccaatgccac
    17881 acgttggcgt tgtccaccag ataaagcagc tggttttcgt ttcaagtatt ctgtcagacc
    17941 taagatctct gctgcattgt ccacacgttt tttgatgtct gctttatcat atttacgtaa
    18001 tttcaagcca aaagccatat tatcaaaaac agtcatatga ggatacaatg cgtagttttg
    18061 gaaaaccatg gcaatatcac ggtctttagg tgccacgtca ttcatgactt ttccgccgat
    18121 atttagttct ccttcagaga tatcttccag tcccgcgatc attcgcaaag tagttgactt
    18181 tccacaaccg gaaggaccaa caaaaacgat aaattcacgg tctttgattg atagattaaa
    18241 atcagttaca gaataatttt ctgcattgtc atatttttta tatacgtttt tcagagccat
    18301 ttctaccata atacgttcca cactttcttt tttagtttta ttaactattt aaagtataaa
    18361 tgaaagcgtt aactaacttc aatgtcatgt tgaacaagaa ttttttcttt tttttgtcaa
    18421 tgtgctagtt ttaagcttta ataaatatcc ataagaaata aaaactgata cactggagta
    18481 aataagtatg ttaacaatat caaaaggagt gtctcttatg aaaatcgctt tgatcgctca
    18541 tgaccgaaaa aaacctatga tggtgaaatt agcaacagcg tataaaacaa tattggaaaa
    18601 acatgaactt tttgctaccg ggacgactgg gcagaggatc acggaagcaa ccggcttgcc
    18661 gatccatcgg tttaaatccg gaccgttagg cggggatcag caaattggag ccatgatttc
    18721 ggaggatcag ttagatttgg tgatttttct tcgagacccg ctggctgcac agccccatga
    18781 accagatgta acagcactta tccgtttatc tgatgtctat gagattccgt tagctacgaa
    18841 tatcggaaca gctgaggtgc tactaagagg actggaagcc ggcttcctag attttcgaag
    18901 aatcgtccat gaaatagaca agcatccact ttcattttga tggataagcg tatggaaaaa
    18961 taacgtttaa tgttcgccta tatgtagcta taaaagctaa acaaactgat aatatgcgat
    19021 ataatacgaa cgtattggat aatataaaca ataatattag tttttcgtat ttgcagtaaa
    19081 tgtgaaaata tgctatagtt tctgtgggaa aagatcccaa aaataataca gagtagaaaa
    19141 taaagcgtta agtgctaaga ggatgggatg ttgcctcttg gacgaaggac gtaatgttcg
    19201 cggttttatt ttcgcattcg ctgcatgata cgatgtagca gctcttaaag gagatgctaa
    19261 aaatgaagaa acaccggtta gacgcacgta tgattgctat tatgggctta ttgattgcat
    19321 tgatggtcac tttgtcccga ctggtagcaa tcgagacccc atttattaaa atcagtgtca
    19381 catttattcc acaagtgatc atgggcattc tttttggtcc tttttggtca gggataggcg
    19441 cagttttagc tgatttagta ggaatggccc tcttctcgaa atctgcattc tttattggat
    19501 ttacattgaa tgcatttatt gaaggagcaa tctacggatt ctttttctat cgaaaagaga
    19561 tcacttggaa aaatgccatt ctggctacgc ttagtgtcac gctgatcatc aacttatttt
    19621 tgacaccatt atggcttgcg ttgatgtacc atgtgccatt gttcagctgg gtcgtttggg
    19681 cgccccgcct gttaaaaaca gtaatatggt taccgattca atcaattgcc atttattacg
    19741 taggacgtag tattccttac aaaaaaattt taagaagttt agcgatccac gctaaataaa
    19801 aaacaagcag tcttcccatc ccagaagact gcttgttttt attgtgctgt gaattgtgct
    19861 tgatagagcc gtcggtaata accatctttt tgaagcagct catcatgggt gcccatttcg
    19921 acaatagctc cctgatccat cactaatatc tggtccgcat ttttgattgt ggacaggcga
    19981 tgggcaatca caaaactggt ttttccttcc atcattgcta agaaggcttg ttggattttt
    20041 ttctctgtca atgtatcgac tgagctggta gcttcatcta agatcaacat agggggatta
    20101 ctgatcatcg ttcgagcaat cgtcaacagt tggcgttgtc catctgatat ctttaaccct
    20161 tgaccgccaa tcttagtatc taatttttcc ggcaaacgtt ctacaaattc atacatataa
    20221 gaggctttta gggcatcatt gatttctgcg tcacttgctt ccggattccc aaaacgaaga
    20281 ttttctcgca atgtactgtc aaatagccaa gtatcttgta acaccattcc aaaactttta
    20341 cgtaatgtat cacgttggat agagcggatg tcatggtcat cgactgtaat tgttcctttt
    20401 gttgtgtcat aaaaacgcat cagcaaatta acaagtgtgg attttccggc ccctgttttt
    20461 cctactatag caatggtttg acctggataa gcagtaaaat tgaaatcttc gatcaaacgc
    20521 tgcttggggt cataagaaaa agaaacatga tcaaaagaga cttttccttt gatatttttg
    20581 ggttccaagg cataggcatc tggcaaatca ggcttttctt ctggctgatc gatcaaatca
    20641 aatgctcgtt ctagaccaga aaaagcggtt tgcagttgtg tcgtgattcc agaaagttcg
    20701 ataaatggtt tagaaaactg acttgagtag atcgtaaagc tggaaatcac accaacagtg
    20761 attgacgaac cactcttcaa tgccaatagg ccgccaacta aaccaatcga taaataagca
    20821 aggtgatcta caaaacgaga agacgggttt gtcaaggaag aagaaaattg tgcccgttgt
    20881 cctttttcat atagatcagc atttagcagt tcaaattgct gttgactagc ttcttcttgc
    20941 tgaaaagctt tcacgatttt ctggttaccg attcgttcgg tcacaaagcc cgagatatcc
    21001 ccaataatcc tttgctgtct atcgaaattt gtttgtgaag cacgagcaac gatccaactc
    21061 acaaggaaaa taattggtgt agaacaaaga acgaccaatg tcagaagtgg acttagacgc
    21121 atcataaaaa taaacgaaag aatgatgatt gccactccag aaaataattg attgaaggcc
    21181 gcagaaattg caatggaaat attgtccata tcatttgtaa atcgactgac gatatttccg
    21241 tgggagtttt gatcataata acgaagtggc aatcgattca gatgagcaaa tgcatctttt
    21301 cttaattttg caacggataa gtaagctaac cgattgctta acacttggat gagccattga
    21361 ctgactacgt tgattaaaac gataccaccg aatagaataa gtaaatggaa cagtcgattg
    21421 aagcggacct gtccttctcc aatcatttga tcgatacttt gaccaatttg taacgtcatc
    21481 acaactgttg caatcccatt gatgattcct agtatcacag ctagccaaat gtcttttgca
    21541 taggcagtaa ggtaaggaat gaatcggcgg agcgtctgca aggataattt ttttactttc
    21601 ataactattc ttcctcctgt gatgcgacga tttcctgata ttctgctgat tgagcaagta
    21661 attcttcatg ggtaccctga gcagcaatct taccttgatc catcactaag atatgatgtg
    21721 cttcttgaat agagcggaca cgttgggaga taataatcac tgtactgcca agataagtct
    21781 gtagcgcctt acgcaaatcc aagtctgttt gataatccaa cgcacttaaa gagtcatcta
    21841 aaatcagtaa tgctggcttg gcaatcaaag ctcttgcaat cgtcagtcgc tgtttttgtc
    21901 cgccagagaa atttttccca ttttccatga cttttgtatc taaaccattt ggaagctgac
    21961 ggacaaattc ttctgcctga gcgattttca gagcttccca acattctttt tctgtggcgt
    22021 ctttcttacc ccattgaagg ttttcacgaa tagtcccggt aaatagtaca gaagtttggg
    22081 gaacaagagc aatttgctga cggagatgat ccagctgcca agaacgaaca tccattccgt
    22141 ccattataac tgtaccggaa ctgacatcat agaaacgcgg aatcaattgt gtcaaagtcg
    22201 ttttcccgct tccggttgga ccaatgattc caaggactgt atttcgcttc agctgaaatg
    22261 taatattttg gagagaaaga ccagaatcag gagtataacg gaagtcaaca tggtcaaaag
    22321 cgataattgc ttcagaagaa aaatcgggag tagtactgac ctcagcttca agaatcgaat
    22381 tttctgtgtc tagcacctct ttcacccgat ttcctgaagc ttcggcacgt gtgaagatca
    22441 cgacgaggtt tgaaacaacg atcagtgcca aaagcatttg attcatataa ttgatcaaag
    22501 caagaacttg tccttgttgc aagctaccaa tatttacttt gatcccgcca actgtcagca
    22561 aacagatgat cccgacattc atgatcaagg ttgtagcagg tgataatagg gcagagatat
    22621 tggaaacacg taaataattg ttcgctagat catttgtgct tttatcgaac ttctctgttt
    22681 ctttttttgt ctgcgcaaat gcgcggatga cacgaacacc gctaagattc tgactaacgt
    22741 gttcattgag ctgatctagt ttttcttgca ctttttggta gagaggaacg gtttttttga
    22801 tgataaaaaa taaaatgatt gagaaaatag gcaataatgc taagaaaaac agacctactt
    22861 cccagtcgat cacaaaagcc atgaccactg acccgatact taaaaacggt gctctgatca
    22921 ataaacgaat gaccattgct aaagctagct gaagctgatt gatgtcgttt gtcattcggg
    22981 tgatcaaggt atctgttcca aaatgattca actcgttgtg agagaaagta ttgatttttt
    23041 tgattagctg attacgtaac tctgtaccaa atccttgtga agctactgaa gcatagtatt
    23101 ggcaaatgat agcacaaatc agaccaatca cagacatagc gaccatccat aagcccattt
    23161 caatgatttt tcctcggtca ttcattttta gtccattatc gatcaaggaa gccatcatta
    23221 aaggcaggac aagttcgaag acagcttcaa gaaatttgaa gaacgggccc aaaatgattt
    23281 gcttacgata gtcttttgca taacgtaata actgaatcat atgattcctc ctattattta
    23341 tttgtccaca attgaaaaaa caagtactac cacattgtag cttaggaaat ttagaatgaa
    23401 aagagaacaa gccttttcat aaatgaaagt tttattatga agaagcttta gaaattgaat
    23461 agactatttt ttttaaaaaa aagaaaatga gaaaacatgc cagtctcttc attcatagga
    23521 acg
//
LOCUS       DAFLVO010000044        22743 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.044, whole genome shotgun sequence.
ACCESSION   DAFLVO010000044 DAFLVO010000000
VERSION     DAFLVO010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22743
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.044"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..161)
                     /locus_tag="L1U99_001783"
     CDS             complement(<1..161)
                     /locus_tag="L1U99_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212322.1"
                     /translation="MLLLIGLILLIIGITKLSKANTIKKEAYELEQKNDEKLNKLHDR
                     ERFILSKEET"
     gene            complement(252..704)
                     /locus_tag="L1U99_001784"
     CDS             complement(252..704)
                     /locus_tag="L1U99_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBN1212323.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(717..1127)
                     /locus_tag="L1U99_001785"
     CDS             complement(717..1127)
                     /locus_tag="L1U99_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1212324.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            1402..1614
                     /locus_tag="L1U99_001786"
     CDS             1402..1614
                     /locus_tag="L1U99_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1212325.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            1617..1829
                     /locus_tag="L1U99_001787"
     CDS             1617..1829
                     /locus_tag="L1U99_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212326.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            1969..2124
                     /locus_tag="L1U99_001788"
     CDS             1969..2124
                     /locus_tag="L1U99_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212327.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGKKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(2121..2345)
                     /locus_tag="L1U99_001789"
     CDS             complement(2121..2345)
                     /locus_tag="L1U99_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBN1212328.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            2423..2611
                     /locus_tag="L1U99_001790"
     CDS             2423..2611
                     /locus_tag="L1U99_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212329.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            2937..3272
                     /locus_tag="L1U99_001791"
     CDS             2937..3272
                     /locus_tag="L1U99_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212330.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            3505..4446
                     /locus_tag="L1U99_001792"
     CDS             3505..4446
                     /locus_tag="L1U99_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HBN1212331.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            4448..5338
                     /locus_tag="L1U99_001793"
     CDS             4448..5338
                     /locus_tag="L1U99_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBN1212332.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            5381..6181
                     /locus_tag="L1U99_001794"
     CDS             5381..6181
                     /locus_tag="L1U99_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBN1212333.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADNIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            6196..7047
                     /locus_tag="L1U99_001795"
     CDS             6196..7047
                     /locus_tag="L1U99_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1212334.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            7248..7709
                     /locus_tag="L1U99_001796"
     CDS             7248..7709
                     /locus_tag="L1U99_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1212335.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            7735..8187
                     /locus_tag="L1U99_001797"
     CDS             7735..8187
                     /locus_tag="L1U99_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212336.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            8293..8487
                     /locus_tag="L1U99_001798"
     CDS             8293..8487
                     /locus_tag="L1U99_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212337.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNGFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            8518..8904
                     /locus_tag="L1U99_001799"
     CDS             8518..8904
                     /locus_tag="L1U99_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212338.1"
                     /translation="MKKLHQLISEKESELQNLEDSLGLGFPIVEQAKMTQISHLRLEL
                     EDLRQIEKSIQLNDNQKIVLEWLKSETILTREAPILSVNAFSDKNLLGKLPDKVRKAY
                     KLLACKQEYEVLSAFAQWGLEQEEAE"
     gene            8901..9104
                     /locus_tag="L1U99_001800"
     CDS             8901..9104
                     /locus_tag="L1U99_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HBN1212339.1"
                     /translation="MNNRHRRITKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASNAIRKFGISILNDDRKWEEMR"
     gene            9101..9397
                     /locus_tag="L1U99_001801"
     CDS             9101..9397
                     /locus_tag="L1U99_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212340.1"
                     /translation="MKIKDGFYASSHGIGGLMLDMPIKNPKTRQKSKFKIGDMVRCKA
                     EEFIYPFRGYVEHVYNHSAIIHIENTMECDKWLAKSKDNLAVARLVDMELINDK"
     gene            9473..9889
                     /locus_tag="L1U99_001802"
     CDS             9473..9889
                     /locus_tag="L1U99_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBN1212341.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCDVNKHSNYEI
                     GQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLVQYR"
     gene            10150..10287
                     /locus_tag="L1U99_001803"
     CDS             10150..10287
                     /locus_tag="L1U99_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212342.1"
                     /translation="MDKEIKVTVKLDLTELKELLNKASDQVEQLQETLDEIANFKIQV
                     S"
     gene            10697..10927
                     /locus_tag="L1U99_001804"
     CDS             10697..10927
                     /locus_tag="L1U99_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212343.1"
                     /translation="MRNYWYISLTNEYPRTIDDCSVRVVRSVQIKKKYSIVEMTREAT
                     PKEIDKCKLLYCGHGFYDEPNIQNNINKNLRD"
     gene            11086..11919
                     /locus_tag="L1U99_001805"
     CDS             11086..11919
                     /locus_tag="L1U99_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HBN1212344.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELKSNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPKRNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            11912..13327
                     /locus_tag="L1U99_001806"
     CDS             11912..13327
                     /locus_tag="L1U99_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HBN1212345.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPENMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTTVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            13339..14868
                     /locus_tag="L1U99_001807"
     CDS             13339..14868
                     /locus_tag="L1U99_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBN1212346.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEYMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKDPTAKAEYVTKKLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            14786..15838
                     /locus_tag="L1U99_001808"
     CDS             14786..15838
                     /locus_tag="L1U99_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBN1212347.1"
                     /translation="MTIETKYWTKRRELEDQARLKQENQTLKKLTSVFPEALKEIQAK
                     LLSQADLHNITYPEMMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            15840..16157
                     /locus_tag="L1U99_001809"
     CDS             15840..16157
                     /locus_tag="L1U99_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212348.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            16284..16907
                     /locus_tag="L1U99_001810"
     CDS             16284..16907
                     /locus_tag="L1U99_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HBN1212349.1"
                     /translation="MSMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            16922..17812
                     /locus_tag="L1U99_001811"
     CDS             16922..17812
                     /locus_tag="L1U99_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HBN1212350.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            17835..18050
                     /locus_tag="L1U99_001812"
     CDS             17835..18050
                     /locus_tag="L1U99_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212351.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            18062..18403
                     /locus_tag="L1U99_001813"
     CDS             18062..18403
                     /locus_tag="L1U99_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212352.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            18403..18774
                     /locus_tag="L1U99_001814"
     CDS             18403..18774
                     /locus_tag="L1U99_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212353.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            18767..19162
                     /locus_tag="L1U99_001815"
     CDS             18767..19162
                     /locus_tag="L1U99_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBN1212354.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGAVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            19164..19541
                     /locus_tag="L1U99_001816"
     CDS             19164..19541
                     /locus_tag="L1U99_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212355.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNKPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            19542..20150
                     /locus_tag="L1U99_001817"
     CDS             19542..20150
                     /locus_tag="L1U99_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1212356.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            20150..20491
                     /locus_tag="L1U99_001818"
     CDS             20150..20491
                     /locus_tag="L1U99_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212357.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGPVVEEAAEVMEG
                     MQNAVDGKSVSEALSRAYSFIADILFEGQFTGEDYRQGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            20733..>22743
                     /locus_tag="L1U99_001819"
     CDS             20733..>22743
                     /locus_tag="L1U99_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBN1212358.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANSFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWI"
BASE COUNT         8217 a         3308 c         4681 g         6537 t
ORIGIN      
        1 gtttcttcct tacttaatat aaatctttct ctatcatgta atttatttag tttttcatca
       61 tttttttgtt ctaattcata agcttctttt tttattgtgt tagctttcga cagtttagtg
      121 attcctataa ttaataaaat aagtccaatc aataataaca ttcaaaactc ctcatttctt
      181 tgatataatt attgtagagt ttactcagaa atgaggaaag agtccatgtg aaagcatggg
      241 cttttttatt tttaatgttg taatactaaa tgttcaagat tatgaggaag ccctaaatat
      301 tcaataattt ggaactgact catatcagat aaatcttgtt catctattgt tctagttaac
      361 atttcaattg caaacatatt agcttcagct tctataccat aaatcataca actaaggttg
      421 tttgctctaa aagctgctgt gcaaatacct ttatggagtc taacgtgggc tatttcatgc
      481 cataatacaa atcttttcat agaaggtgat aggttttgat taattaatat cacataacat
      541 cttttattgt gtatcgtttg tcctaatgtt ttattcccta aatcagtttc aattaaatct
      601 atatcagaat atttgattat tttatatgga ttaatcgcat cagatccaaa ctctacaaat
      661 aatttttcta tttcttctaa tatccagtat ttgtttaaat gcataccaaa gcccacctat
      721 tgacgatatt ttttaggagt gaattttttc tttgctttaa ctttggttaa ggcaagtgca
      781 agttgaatgg catcgtataa tttttcctta tcttcatcgt ctaaaggttc accataataa
      841 tttgtttcag catctgaatt caagccttca agtaattttt cagcttgtaa agcaatatct
      901 tgtttatctt tttctgttaa atcataataa tggcgtttat cagtacgtcc taaaagataa
      961 tcagttgata cattaaagta atctgcaact ttttgtattt tatctccaga tggagtactt
     1021 ttattccatc tagacatgct tccatttccg aaatttaact ttctttcaag ttctgccaac
     1081 gtcattgaac gttcttttaa taagattttt atacggtcta atagcatagg atatgcattc
     1141 ctttcaaaat accgacaaaa aaagtatttt tctgcaaatt atctatttac aaatagagaa
     1201 tttgcagtta tactagtttt gtaagcaaga tatttacggc atacaaagac taaaagcaat
     1261 aaactaatag tctccccaga catcagtaag ctcgcttttt gtgcgctgta ttttgtatgc
     1321 ttacataata gcatatttgc agtttttgtc aaacttatta gacaaaaata ttagaaaata
     1381 ttcgataagg gggtatgaag catgacttta aaacagcaag tattaattgc tttagtaaag
     1441 aaaggttgga gtcaaagaga gttagctcga cgaatgggta tatcaattac ttatttacga
     1501 gatatcttca tcgaaaaaag aaaacctaag gaacgtttaa aacaaatcga agaacttttg
     1561 gatatcaagt tagaagtaga ttctaatgat cagccatcag aacaggaggc gtaaaaatgg
     1621 tacaacgttt gagcaaagcg gagtttaaag agaaatataa gtattctgaa agtacttatc
     1681 aaagaagaat gaaggaattt aaaaaatcac gttttagtga ggggtataac gcagttactt
     1741 ccaaagaaat aacaattgat gtcgatttat atgaacagtt tagaacatgg cgttctaaaa
     1801 atcgatttag agttagagct gtttgttaat agctaaaaaa tctaaattca ccacttctga
     1861 aaagaggagt tgctgctctc ctttcaagtt tgccaaagtc cacgtttttt cattttggca
     1921 actcctcttc ttggaggtgg tgacggcgag agacgaagga gggatgacat gaaggaagaa
     1981 tcaaaaatag ggattttgaa tgagaacaat tacacaagat taattattga aacagaagaa
     2041 gggaaaaaag tagcagaagt tacattgacc gatgcaactc ctgctgacgg ttatcgtatt
     2101 cgattaactc ctaaatatga ttaacctttt ggtgggtgtg gatcgtttcc gtgactatca
     2161 cggctttgaa tttttccatc tctgccatga ataaatagct cagatccttg atttttagaa
     2221 atctctctag cgatttttac tgcttctgat tttgtattag tatgtgcagt cgctttagaa
     2281 tttccagcac ctttgacatt ccaaccacca ttggaattag gtacaacatg ttgatttttt
     2341 cccatagttt tcacctccat ttctatagaa atattttatc aaatagaaat ggagaaattc
     2401 aataaacgaa aggagaagtg atatggcata taccttgcaa caagaacatc aaattctcgg
     2461 tttgattaaa caacgcagga aacaattaca agatgaccgt gcagcgctta gaaaagccga
     2521 tgagctatca gataggcaag ctgaactaat tgcttctgaa cttgaggatt tgagaatgct
     2581 agaaataaaa aatagggaga ttagattatg aagaagacag acacactttt tataggattc
     2641 attttggggt tattagtgat tgtagcgcac caaagtatta tcgggggaag cttgttcgca
     2701 gcattgatgg ttttaatcaa tctgcttgat tcaaaagaaa ggagcaacta tggcacgaga
     2761 agaagcgcta aaaatcggta aagtgattgc tgataatcgg tggggaaata gccgccctat
     2821 tattttaagc aagcaacata tcgaaaagca aaaagcatgg caacaaataa aaaagtgact
     2881 ctgccagcca gcaaagagtc acatacaaat ttataaaact aggagaatta tatcacatga
     2941 ataagaaaat tgaaaatctt atcgaagaat tgaaacgtga atgccaaaag caaggtgttt
     3001 ctattatttg tacagcccaa aaagaagggg aacttaaaag tctcgtttat ggtgagacaa
     3061 cagaaatttt actttgtctt gctatgcaag aagaacattt agatgaaaat ctcccattgt
     3121 cagcacatat tatgcgtaga attgctgtgg atgcttacga acaagcgaaa aatgaagaag
     3181 aaaatcaacc ttcaaatcat acttttgtta ttaataacaa ggaagattta gctgatgtga
     3241 tgactcgtat tctcaagggg gaatttcaat gatgaatgaa aaaacaattg atctactcat
     3301 tattttattt ttcacgttag tgattgtagc gaaaagttat gtaatctttg gcttgttatt
     3361 cgcaattacc atgcttgtgc tttgcgtgtt agcaagcaga aaagaggtta aacatgaacg
     3421 agttagcaaa tcttgacaac tatttaactg atcctgatta tgctaaacca ccatatgaag
     3481 caccaattga tgaggaggat gaagatgagt aaatctacct tagaaatgag ccatcaagaa
     3541 tggcttgaag accgtaagaa aggcatcgga ggttcggatg ttggaacaat tttaggattg
     3601 aataaatgga aatctcctta tcaactatgg ctagaaaaaa caggacaagt agtacttgaa
     3661 gaatcaggaa gtgagcccgc ttattggggt aatgttttag aagaagtggt tgctaaagag
     3721 tttcaggaac gtacaggcaa aaaagtacgc agaagaaacc aagtatttga acatccatta
     3781 catccatttt taagagcaaa tattgatcgg gaagtagtgg gagaaaatgc cattctggaa
     3841 tgcaaaacag ctaatcaatt tctcggtaaa gaatgggaag gcgaagaggt accgcttagc
     3901 tatctctgtc aagttcaaca ttacatgaac gttctaaaca aagactattg ttacatcgct
     3961 gtcttaatcg gtggtcaaaa atttatctgg aagcggattg aacgagatca agagctgatc
     4021 gatacaatca ctgaacaatt agtagagttt tgggaaacaa acgttcttgg aggtatcgag
     4081 ccaattattg atggtagtca agcgacagct gatttcttga aagagaagta tgcagatgtt
     4141 gaagacgttc aaacgacgtt accaattcat ttcgatgaac tagttgaaca gaaaaacgaa
     4201 ctcaaacgga ctaagaaaga aattgaatca gctatccgtc aagtagacaa cgagattatc
     4261 agcgagctag gtaaacgtga agccagtatc ggtatcactc aaaaaaacat catcagttgg
     4321 aaatttgtcc gtacgagacg tatgaactcg aagaaactag cagagaaata tccagatgtc
     4381 gcaaatgatg aagagattta taacgttact gaatcaagaa ggctaaccga aagggagatc
     4441 aaataatatg gcaacaaatg aatcgttaaa aaatcaattg gcagcaaagc cacagaaaca
     4501 agttgcacca ggtcaattag gacttaaagc tttgatgaat acaccaacaa tgagaaagaa
     4561 gttcgaagag gtgcttcatg acaatgctaa tgcttttatg tcgaatgtta tgactcttgt
     4621 atctaatgac agttatcttg cagatagtga accgatgtct atcatgagtg gtgcgttaac
     4681 tgctgcaaca ttaaatcttg ggctagataa gaatttaggt tatgcatatt tagttccatt
     4741 caatagtaaa aacaagcaaa caggaaaatg ggaaaagaaa gctcaattca tgcttggcta
     4801 taaaggatat atccaattag cccaacgatc aggtaaatac aaagcattaa atgtgatcga
     4861 agtttacgaa ggagaactaa aaagctggaa ccgactgaca gaagagtttg agtttgatcc
     4921 aaatggtaga acgtctgatg aagtcattgg atatgttggc tatttcgagt tactgaatgg
     4981 attcaaaaaa actgtctatt ggaccaaaca agaaatcgaa gctcatcgga ttgctaacaa
     5041 taaagatcgc gataagacaa agttaagtgg tgtgtgggca tctgattaca atgcaatggc
     5101 acgaaaaact gttttgagaa atcttctttc taaatgggga atcttgtcca tcgaaatgca
     5161 agaagccacc acatcggatg agagagtcca aagggttcaa gaagacggca gcattattgc
     5221 tgaaacagaa gttgaagaag atattcctga aagaaaagaa gcagaggtta tatctgaaga
     5281 aaatgaagat gtacaaactg gattatttga tgcatctaat ccgccgttaa acaaataatg
     5341 agggagcttt ctcccttgct tttctagagg agaaatacga atgaacacag gatatgtcaa
     5401 attacatcga aaagtgatga attcattcgt ttggaccaat ccttatatgt ataaattatg
     5461 gaacttgtgt ttgatgaaag cgagtcatga gaatcgcaag atacttttta atggaaaaga
     5521 gatacaagtg aacagcggag aattcgtcac agggcgcgat gctatcacat ctgagatgaa
     5581 cgaaggcgtg aaacgtgaac atcaagtgaa cagcggttct gtatggagat ggctaaaaca
     5641 atttgaaaaa aacggaatgt tgaacatcaa atcaactacg aaatacagcg ttatatcaat
     5701 aaaaaactgg tctttgtacc aaagcagtga acaacaaatg aacatcaaac gcacaacaag
     5761 tgaacaacaa gtgcacacaa acaagaatga aaagaattat aagaatgaaa agaataataa
     5821 aacatcatcg tcgcaaccac gcaaaaagcg tgtttacgac accgactcag tttactacat
     5881 tctcgcggag gagttattca aacagatttg tcagaatcag gaaatcaaaa agccgaatct
     5941 gcaaagttgg gcagataaca ttcggaaaat gatcgagatc gacaagcgga ccgaaaacca
     6001 ggtacgggga atgattgaat ggagtcagca caatgtgttt tgggcatcga atattttatc
     6061 tgctaaaaaa ttgcgagaaa aatacgacac aatggcagcg caagccaatc gtgattataa
     6121 aacaaaacaa actaaaacgc ttgaatacga gaaatttagc acagatgagt tgcctatttg
     6181 agaggaggcg taggcatgga aactgttggg gaaatcatgg aaaagctgat acagaaagtg
     6241 cttgtccaac gtggcgaatg tcctgaatgc ggacagcctt tgtatggatg gcgtacgaag
     6301 aaccctgatg gctcagaacg ttgtaagcca acctgtatgc aatgtgggta taaagcattg
     6361 cgagttcagg aagacttaca aacagaacga atttacaacg agagcctgaa agcaagagca
     6421 atcaattttt tcaaaggtgg ttctgttgtg cctaatcaag cgttgtttga ttgcacattg
     6481 cagaattatc aaattgtcga tcaagaaaca agacaagcgg ttgaagtaac caaacgcttt
     6541 gttaattcag tcttgttagg aaatccaagt caccttgttt taactggaaa acaaggaaca
     6601 ggtaaaagtc acctagcgat ggcagcggct tgggaagtct tgaagcgatc aaactacgat
     6661 aaaaaaatct tatttatcgg gttacaggaa atgctggatc aaatcaaatt ttcgtacaac
     6721 aatcctgaac tcagaaaaac gattgaggga tcgttgattg cagatatcaa aacagcggat
     6781 ttagtcatca ttgatgatat cggttcagaa ctaggaaaag atgcatcaga tagtcgagcg
     6841 tttggcataa acacgctaaa ttcgttcttg gatgcacgac agaacctagc aacgattatc
     6901 acaacgaact tgcttggtga agaactgaaa aaagcttacg gtacgagaac aatatcaaga
     6961 atgtttgtca actctgatgg atttacgatg gtattttctc aaacagcaga caagcgcata
     7021 aaaccagtca aaggagcgat cgcatgaatt tgactaaaca agaaaaaaga atctgtcgtc
     7081 agataatgtt gcaaattata ggtgatcgtg acatggacga attatctcaa caagagagtc
     7141 gaatggttcg gaagataagt aagctaatta tttatcggga tacagaaaga tttctcactg
     7201 ttttaggtaa cgtctacgag aatccagagt tattggaggt agagtaattg ccaaaaatat
     7261 tagatgcatg ttgcggtagt agattgttct ggtttgataa gaacaattct gacgtaacat
     7321 ttatggattg tcgtcagcag tatgaagaat tatcaacagg tcatgtgatc aatgttgatc
     7381 cagatgtggt cgcagacttt cgcgatatgc cttttgaaga tgatgtgttc gatatggttg
     7441 tatttgaccc gccacactta agacatgtcg gcgaaaactc atggcttgcc aaaaaatatg
     7501 gaaaattaga cgaactttgg ccagaagaca tcaggcaagg ttttgcagag tgtatgcgag
     7561 ttttacgacc ttcaggaaca ttaattttta agtggaacga ggaacagata ccactttctg
     7621 atgtgttaga ggctattgga gaacagccat tgtttggtaa taaacgaagc aaaacacatt
     7681 ggcttgtgtt tatgaaaaaa ttcagctaac ggaggaaaca aaggaggaaa agtaatgaag
     7741 attgtattaa ataaatgttt tggtggcttt gggttgagcc atgaagcaaa aatggaaatt
     7801 tttaaaagaa aaaatattga agtattccca tacatcaata actttagcta tgactcagat
     7861 gatgaataca cgagatacac aggccaaaag ctaggttcga tggattttat ctactatttc
     7921 aaaaaagacc cgaaaatcga caaagttaca ggaatttata gcgaaattga ccgactgtac
     7981 ggaattgctg atgattccag tttttcaagt gattcaaaca gaggtgataa ggacctcgtt
     8041 gctgttgtcg aaaaactagg aagtgaggcc agtggaccat atgcaagtct taaagtcgtt
     8101 gatatacccg atggggctga gtgggaaata agtgattatg acggcgttga aactgcacat
     8161 tatggttttc aaacaggtag tatttagtcc actaatgaca actaaagagg aggcagaagg
     8221 atgagtgaag atgaatactt tgaacagtag tctattaacg acagagattt ttaactggaa
     8281 aggggtgtag tcatggacgc atcggaagta gtaaataaaa ttaatagtct caaagaggtt
     8341 ttcggagacg tcgaagtagt gataaacgca caaggctatg acaacggatt ttttaagcag
     8401 attaccgaca ttagcattca gcaaggaatg gaagacgaag atggaaactt tatcgatgaa
     8461 gtagccattt tagtgacttg cgagtaagta attgacagct aaagaggagg cagaaggatg
     8521 aaaaaattgc accaactcat atctgagaaa gaaagcgaac tccaaaattt agaagatagt
     8581 ttgggattgg ggtttccaat tgttgagcaa gctaaaatga ctcaaatcag tcatctacga
     8641 cttgaattgg aagatttaag acaaatagaa aaatcaattc aactcaacga caaccagaaa
     8701 atcgtgttgg agtggttgaa aagcgagaca attttaacta gagaagcacc aatattatct
     8761 gttaatgctt tttctgataa aaatttacta ggaaaattac ctgataaagt acgcaaagct
     8821 tataaactat tggcttgtaa acaagaatat gaagtcctat cagcattcgc tcaatgggga
     8881 ttagaacagg aggaagcgga atgaacaaca gacatcgcag aataacaaaa ctaagaaaac
     8941 aggaactgaa tgtactaaag acaaagtttg aaaaagaata tggaatttca gcagaagaaa
     9001 catataaagt ggcaagtcag tttgttgctg atgcgagtaa tgctattcgt aagtttggga
     9061 tttcgatatt aaatgatgat cgtaaatggg aggaaatgag atgaaaataa aagacggatt
     9121 ttacgctagt agtcatggta tcggcggttt aatgctagac atgccgataa agaaccctaa
     9181 aacacgtcag aaatcaaaat tcaaaatcgg tgacatggtc cgatgtaaag cagaagagtt
     9241 catctatccg tttcgtggat atgtagagca tgtctataat cattcagcaa tcattcacat
     9301 tgaaaacacg atggaatgcg ataagtggtt agcgaaaagc aaagataatt tagcagtggc
     9361 tcgtttggtg gatatggaac taatcaatga caaataaaaa agccggatcg ctccgactga
     9421 ttcaataaat ccaacacatt tattatatca cataaaggag cggtttgact tgatgcaatt
     9481 gttacgagag gtagatttca aacagacaag atgtaatgcg agagatgtgc tgaagaactt
     9541 tcggcgtttg gagcggatgg caggtcgctc tttgatagat attaagtcgc cgattattac
     9601 ggatatgccg aaggcaccga agcacggcaa taaggcagaa gacgcgatca ttcagatgat
     9661 ggatatagaa gcggagagag acgcaatact agcggctttg atggctctta gtctgattag
     9721 ccgtcagata ctctactaca gcttctgtga cgtaaacaag cactctaatt atgaaatagg
     9781 gcaattgata cgaggatacg gagagaagaa tgtagagaag ttgaaatcca tcgcattaat
     9841 cgaatttgca gaagcataca aaaaaggcgt gttagttcag tatcgttgat tttgtagggt
     9901 ttttgtaggg atagtgtagg gtttttgagc ggtttaacgt gatattatgg tagtgtcgaa
     9961 agattagtga taggtctgag acaaaataaa atgtaaggga ggaaatctcc ctcatcgttt
    10021 taacttaagc ttcgatagac agcaacggaa atattaagaa taaggatgtg aatttcaact
    10081 ccttctaaat tgttcttatt atctatcatc cgttgttgtc tattaattta tgcatcggag
    10141 gaaaaacgaa tggataaaga aatcaaagta actgtcaaat tagatttgac tgaactaaaa
    10201 gaactgctca acaaggctag tgaccaagtc gaacagttac aagaaacttt agatgaaatt
    10261 gctaatttta aaatccaagt ttcttagcag tatatttttt agcagctgca ctcataaaat
    10321 cataccaagt atcagaaaaa tataacttaa ctaaataatt aaaaaaggtg ggtaaataga
    10381 aatgacggcg ttaataattt caatttttgc gctctgtctt aatgtctata tgattggatt
    10441 taaaaatgga caaaataaaa aatagtagca gccgagaata attttatagt gtcactgtgg
    10501 cggaaataga agacgcaaag gtggaggtag gaagcgtatg gcgcactatc gggaccttgt
    10561 acaaaactag aaaggactag tacgtgtgtg gtgcgagccc tagggaggaa caggataacc
    10621 gcctgtgtgt aggttgctat tacatattag atcactcttt gagtggtctt tttatttaca
    10681 taaaggaggc tacataatga gaaactactg gtatatatcg ctaactaatg aatatcctcg
    10741 aaccattgat gattgttcag tgcgtgttgt gcgttctgtc caaatcaaaa agaagtactc
    10801 cattgttgaa atgaccagag aagctacgcc aaaagagatt gataaatgca aacttcttta
    10861 ttgcggtcat ggtttctatg atgaaccaaa cattcaaaat aatattaaca agaatttgag
    10921 ggattagaat gcaagaaatg gcttaaaaat ctccaatcag gacaaatcaa gttagacaaa
    10981 gtttccgatt taaagatatt gattgaagct gatttaatgc taaaagatat tgaaaattag
    11041 aaaacaaaac tcaacctaag aagattgcga ggtggtgtgt attgaatggc aagacaacgt
    11101 gatccaagac gtgatgaagc caaaagaatt tggttagaat ccaacggaga aaagcagtta
    11161 aaggaaattg catctgaatt aaatgtttca gattctcagg ttagaaaatg gaaatcgcaa
    11221 gacaaatgga gcgctgaatt gaaaagtaac gttaccaatg gcaaaagtaa cgttactaat
    11281 caaggtggcg ctcctattgg taatcaaaat gctaaaggta acaaaggaaa cagcagagca
    11341 tcaccgccaa agagaaataa gaatgctctt aaaactggtg agtatgaaac aatatttttt
    11401 gacacgttaa ccgataatga gaaggacatc tattctagtt tgaatgatga tccttctttt
    11461 gctttgtccg aagaaatacg acttcttaaa ataagacaac ttcgaatgat gaaaagaatc
    11521 caacaagctg aagctggact aaatgatgaa gaagtcgaac gattgcagca gctaagaaag
    11581 attaaaactc cgattgaaaa aaatggtaaa aagctagaaa tcaagcgtga ggttatgcaa
    11641 gatgtgcaga ttagcagaaa aaaacatcgc aaaattgatg atattctttc aattgaagat
    11701 tcattgactc ggattagcaa ccagttagct aaagccatca agcaaatgaa tgaactttat
    11761 atgaatgaat acagaactga tttaattaaa gctcagactg ataagatcca agctgagaca
    11821 aatgaaattg gcggaaataa ttcaggtgaa gaaatagaag aatggaaaca ggcagtttta
    11881 aatgccgcaa acaaacgggc ggtgaaagaa aatgaataat gaatttattc cttttgctga
    11941 tattggttct gccattgatt attactatga taaaccagta gctttttgcc aagatatttt
    12001 gcatttgaat cctgatgaat ggcaagaaaa tgttttaaat gatttagctg aattttcaaa
    12061 ggtttctgtt cgttctggtc aaggagttgg aaaaacagca ttagaagcag gagcaatact
    12121 ttggttctta acgtgtcgac cctacgctaa agtaatagca acagctccga caatgaagca
    12181 actttacgat gtactttggg cagaggtagc taaatggtta aatgatagct tgatcaaaaa
    12241 cttactgaag tggacaaaga ccaaaattta tatggttggt gattcagagc gttggtttgc
    12301 tacggctaga acagcgacta aaccagaaaa tatgcaaggt tttcacgagg accatatgtt
    12361 gattgtggta gatgaagctt ctggtgtgtc tgatccaatt atggaagcta ttcttggtac
    12421 gctatcaggt tttgataata agctgttgat gtgtggaaac cctaataata ttgaaggtgt
    12481 cttttacgat tcccacaatt cagaccgtga taaatacaga gttcataaag tatcaagcta
    12541 tgatagtaaa cgtacaaaca aagacaatat agaaatgatt cttaaaaaat atggaaaaga
    12601 aagtgatgtt gctcgtgtcc gtatttttgg agaatttccc aaaggtgcgt tggattcatt
    12661 tatcagtctt gaaacggttg aattggctac agaaaaacaa attagtgatt ctttagtcaa
    12721 taaaacaacg gttgctcata ttggtgttga cgtagctcga tatggtgatg attctacgat
    12781 tctctttcct agaattgcta ccagggcatt ggagtatgag aagtattcaa aacgtagcac
    12841 tatggaaaca acaggatatg tcatcaacat ggccaagaat ctaatgagtc aatatccgag
    12901 tattgataaa gtgatgatta aagtcgatga cactggtgtc ggaggtggtg taaccgaccg
    12961 cctagaagaa cttatagaag acaagcatta tccttttgag gtgtttggag tgaataacgg
    13021 ttcaacatca gaagacgatt tttacgataa tttaggtact caactatggg gaaacatcaa
    13081 ggaaatgtta gaagaaaata tgacagcaaa tcttaacgga gaacagcctg ttattgaatt
    13141 gccttctgat agttcgttaa tcaaagaatt aagtactcgc aaattcaaaa tgacaagtag
    13201 aagtcgtata cgtttagaaa gtaaagatga tatgaaaaag cgaaatattg gtagtcccga
    13261 tattgctgac gcactggctt tagcgtttta tgagccacca agtcactatc aatttattca
    13321 attttaggag gtgagttttt gattagtaca gtattatctt tagagagata taagaagcta
    13381 cgtgttaaat atgcaacaca aattgaagat ggaatgtttg atccgaatgg ttttatagaa
    13441 tatatgaaac cattttttgc tgatcgcgaa agaaaatatc tagcttatac tagcgaaaag
    13501 aatgaaatag acaatagacc aaagcctaac actgatattg taaaagttaa taataaactt
    13561 catgctggta tgtattcaat tgtcgtagac caagcagtca atcattttac tggtatacct
    13621 atcaaatggg attacgatgt atcggaacaa aaaagaacac tcattcaaag attaaaagat
    13681 aaattcttaa aaaatgatat agaacttcca acagttccag aagcttttaa caaattaaca
    13741 agcaatcttg attccatgag attcgcaatg cttgattctg aaactgcaac ttttcaagga
    13801 gcttgtggag tagctttccg attgttagag cctgtggaag aagatgatgg ttggaagtta
    13861 agagcaagta atattgaacc ttggagagca gaaagatatg gaaatgccgg aatctatatc
    13921 aaagaaaagt atgactctta ccagaaaaaa ttttttcaag aaatgaaagt tatgacaaga
    13981 aataaaattc tgacatatgc ttgctatggt gatttgaatt ttgttacaag cggaacgttc
    14041 aaaaaaattg atgagaccga taaccctttg gggacgatta ccttggcaga atttaaaaat
    14101 aatacgaatc gttattgtga ttttgaagta gctgaggaaa ttggagatgc aattgatcgt
    14161 gctttgtctg atcaacaaaa cgaaatcgaa caatttaagc ttgcgtacat gcttgttact
    14221 ggcacaacaa tgagcaaagg cactgctaaa gaaatgatga atcagctagg gattatcaac
    14281 ttaaaagacc ctactgcaaa agctgaatat gtcacaaaaa aattagcaaa agatttcaat
    14341 gaatatcata tggatctatt gaaaaaacag ttttacacca tttgtaaagc aatcgatttt
    14401 aacgatgagg tgtttaaatc aaacagttct ggagaagctc gcaagtggca aatcattagc
    14461 ctagaagcga aaacaaatac taaagagcaa tattttagag aaggattgaa agaatgcgca
    14521 gaaacaattg ctgcttttct taagtttcat gacaaagtag aaattgagcc tgaaaaaatt
    14581 atttttactt tctctagatc tttgccaact gatttaagtt atttagctga agctttacct
    14641 aaacttgcac catacgtatc caaacgaact attcagagcc aaattccatt tgtaacagat
    14701 gttgattatg aaaatgaaat gatggaattg gaaagtggaa gtgcttatcc agatagtgaa
    14761 tacaattttg gcggaggtgg caatagtgac gatagaaacg aagtattgga ccaaacgtcg
    14821 agaactggag gatcaagcaa ggctcaaaca agaaaatcag acacttaaaa aattaactag
    14881 tgtatttcct gaagcactga aagagataca agcaaaacta ttatcacaag ctgacttaca
    14941 caatatcact tatccagaaa tgatggagtt ttacagtaca agtaatcaga aaaaatatcg
    15001 tgaatatgtg gaaaaaaatt ataagtcatt aaaaatgtat gatgcaaaat acaaagagtt
    15061 tatcgatgaa ttttttccac catttgacta tgcaaaagtc aatcgcttat tacaaatacg
    15121 atcagatgta tttaaaattc ttgcagaata tgcgatggat gcagatgtga atcaatattt
    15181 ttctgatcgc ttagaggaaa ttcttcaaag aacatattct tctaatgcta atgtttttgt
    15241 tcaactttta aacgttgata taccaaatta tttaccagaa aatgaaatta aacattattt
    15301 gaactatcca tggtcaggaa agacattttc aagaagactt tggggaaata tttcatcgct
    15361 tgaacagaaa ctctctaatg ctattgtaaa aagtgttgct agtggagaag gcgttataca
    15421 cgcattaaac accatgagat tagactcaga aatttgtgac atgtttaagt tagaagaatc
    15481 aaagtataac aaagcgatag aaaatctcgt tcgaacggag tatgcaaaat ttgcacaaga
    15541 tggtattgaa aaatcatatt tagaaacagg tattgaggaa tacaacgtat tgactgcaaa
    15601 agatgagaga gtttgccgga tttgtggagg aaaggcaagt aagaatccct ataaactgaa
    15661 agatgctgtc ataggtgaaa atcgagcacc tttccatagt cgttgtagat gtacggatgt
    15721 tcctaattta ccaaaattag gaaaggatat tgatgaagaa tatgaccgtt tatttggcga
    15781 tttattagat gagtttgcac atgattcttt tggaattaat ttgaaacgga ggaagtagaa
    15841 tgaaagattt ttttgaagca gtactaacaa ttaatgtaaa tgctgatatt gcagaagcct
    15901 acaaaacagc tattgagtct gagaaccatc ctaatggctt gagagaccat tggaatggca
    15961 attatgccta cgtggttatt ggcgatcaaa ctgttaatta tcaagataat actccagttg
    16021 ataagaatac cgttaattta acgattcaat tattatctca ttcattacca aatttaaaag
    16081 aaacagttga ttggtatgaa aagatgggat gtattgttgt tagaactgac tacaaagaag
    16141 gaaagtctag taattaggct tttttatttt gtccgaaatg acgttaaact agcgcaatac
    16201 tgggcttggt tgaatggtgg ggcgcaacta ttaaaactca aagcaatgcg gggcgtgaaa
    16261 acgaatcgtg gggcgaaagg agaatgagca tgaaacacaa atcattaatg ccaatgaatt
    16321 tgcaatactt tgccgaaggt gacgatcaaa agttttcttt tgatgacttc aaatcttttg
    16381 tggaatccaa tgaagaagct caaaaattta ttcagtcaca atctcaaagt gttgccgaca
    16441 aacaattgga agcttggaaa caaaataact tagataaaat taaacaggat accatcaagg
    16501 aatatgagga atctaagaaa aacaagtcac ctgagcaaat tcaactggaa aaactacaag
    16561 ctgaatttga agcagaaaaa gcgttgcgtg tgacaagtga taataaagca tttgttgcag
    16621 aacaaattgc tggattagaa ctagatggag agttaaaaga gtctatttct caatttatgc
    16681 taaataatct tgttagttcg gatacagatt tcactaagaa tgctgttgaa ggttttacaa
    16741 gtgttttgaa tgcaattaat gagaaacatg cagatgcatt aaaagaacta caaatgaagt
    16801 ctgcatttgg tggaactcaa caatcgaata accaggttca gcagaacaat gaaacattaa
    16861 caaatccaga agaacaatta ggacaaattc ttcaacaatt taactaggag agtgaaaaat
    16921 tatgaaaaaa acatctttaa ataatttaga gtatttggat atttcaccag cgattaatgc
    16981 tatgcaagta ccaaatacac cttttttaag ctatttactt ggtgctggaa aaacagagcc
    17041 agcaaactcg acagaaatta aatggcgtga atatgatatc aacaacgatg attcttctga
    17101 aaaacttgag ggcggagaat atccagatgc tgaatcaggt cgaacttggt ttaacaacta
    17161 tactgaaatt tttagaaaat caacctctgt atctggtaca ttagatgcta ttaatgtgaa
    17221 tggagtcgga aatgaattaa ctaatcaagt agcactacgt ggtatggaaa tgaaaattga
    17281 tttgaaccga aaattgatta ctggtgtaaa agctgatgaa aatggttcta aaggtcgtcg
    17341 aatgaatggg attttgaact tgatcaattc agcaaataag gcagaaacag ccactgcggg
    17401 tgcagtaaca agaaaagata tcgatacttt atttaaattg atgtatgaaa aaggttatat
    17461 gggagaaaaa ctatgcttga tttctccaga tatgcaggag ttaatgactg atgagttaga
    17521 tggaaaatca acaaaaattg ttcagttcgg ggaaagagta acttttggat tgcaaattgg
    17581 aaatatcgtg tctaattacg gtacaggtat tgctctacta gaaccatcat tgccaaaagg
    17641 aacaattgcc gcaatcgata ctaattatgt gaaactacgt ccattacgtg aatggagagc
    17701 agaagaactt gcaaaaacaa cggattctag acgtatcggt cttgtaggtg aatactctct
    17761 tgaatacaat gcttcaaact ctggggcaat tttaaattta aagtctgaat aaaagggagt
    17821 tagtactccc ttttttgata ggaggaatta cagtggtaaa aaaagatgaa actaaaaaag
    17881 atgaagtcgt gaaatataga gtaggtaaaa ctaaaaattt tgttgggttt gttcatccta
    17941 aaactcgtag atttatcaca gcagattcaa ataacgaatt tatcatttct atagatgata
    18001 aagaagcaat tgcaattttg gaagatgcaa ttgatgttaa tgaaatttag gaagtgatct
    18061 gatggatgaa tcgctaaaaa cggaaatcat tgagtctaca aaagaagatt ttccagattt
    18121 gagtgaagaa cgcataacta atttattaga aataattttg ctagaaattg aatcatacaa
    18181 cacttgtaaa aatgatattt catgggaaaa gttaaaaagc gtgattagtg aagtgttgta
    18241 taaaataata aaaaatgaat cagaaaaaac agtatcttca gttagacgtg gcgatacaac
    18301 gattagttat gcttcaacaa caaatgatgt tagtgagtta cttctaggct atggtgattt
    18361 gatacgaaga gttattggtt gtggaggatt ggagtttttt taatgaatga agcagatatt
    18421 ttagaaacta cttatgaaga tagttgtatt attgaaagac tgacggacat tgaagattct
    18481 aatacaaata ttactattca agattacaaa aaagtatatg ataatcctat ttcttgcgct
    18541 ctttcacaag gtcaaatcga tggactagca gtcatagaag atggagagat ggtaaatgtt
    18601 tcaactgaca catataaatt atttgttcat cctaagatta aactaaaaaa aggagatcga
    18661 ataacaataa ctcaaaaggc cagtggctta attttttctc tatttgctac taagcctttt
    18721 tactatccta gtcattgtga agtgaatttg ataggaagtg agaaaaatgg gtaatctcaa
    18781 atatgaatca aatgcagaaa agatcattga gaattttaaa aatatgactg taattgctca
    18841 aaaagaagga atatccttcg ttaacgattc aatgaataaa gtcgttagtt tagctaaacc
    18901 attaactcct gtaaaatcag gtaatttaag gcgaggatat cgtgtagtaa aagctagaaa
    18961 actatcaagc ggtcgaattg ttggagcagt tataaacaat gaacattatt ttaaatatgt
    19021 agaagaaggt cataggacta aaaatggtgg ctttgtcaaa gggaaattca tgttaactcg
    19081 tgcaacgaat cttgcaaata tgtcttatat tcctcgaaga tttaaacaaa tggcaataaa
    19141 aatcgttaag aaaggaaagt aacatgaaag atgaaatcat tgctgcaatc agtagcaaat
    19201 taaaagaaat ctatcctgat gggacaatat atcttgattc agttatgcag tcaactaaag
    19261 atttttattt cgttttatca gtaatggaat ctggaactga aaatgtagga attgatattc
    19321 aaaatgtttc tttcttaatt gatattgcat tgattgataa taaacctaat agaaatttaa
    19381 ttaatgaatt agtctcacgt tgtgggactt tttttaatac gattacaatc gatgagcaaa
    19441 tattatttcc aaaagcctat ttacctgatg aagcagatgg tgttcaacat attcgtttta
    19501 cattagaatt tccacaatat attgaatgga gtgaaagata aatgggagaa aaaagaagta
    19561 aaaccggaat tatttctgtc gaaaaaccta cttggtttcc tttggaagat gagacaggga
    19621 attttccggt atatggtact gcgttgccaa tgggaacagc agtaagtatc aaaccaacag
    19681 ctaattatga aacaacacaa gattatgggg attcagtggt tcaagatcaa tttacagctt
    19741 ttggtggtgc agaagttgaa ctggaagcaa atggatatac tcataaagtt ttatctacaa
    19801 ttactggagg gaaaattgtt aaaggtggtg ccttgcgttc tggagaagat attgcgcaag
    19861 atggtgcgtt tgcatataga cgtaaaaaat cgaatgggaa ataccgttat acggtctttt
    19921 ataaaggaca gtttgctcta gattcagatg aaacatcaac gattgaagga agtaaagtaa
    19981 gttttactca tccaacttgg aagggttcat ttgtagatgt accaggactt ggatatatgt
    20041 attcagttga tgaagatgat gaaggcgtgg ataaagcaat gatcggaaat tggtttacaa
    20101 aagtagcaat tccaattgaa gaagcagaac tttcaggagg tacagaataa tgtcaaaata
    20161 tcaaacaacg attaaattaa cgaaaaaaga tgaagaaggt aaatatgagc aagtacaatt
    20221 taaatctgct gaatttctac caggcccagt cgtagaagaa gcagcagaag taatggaggg
    20281 aatgcaaaat gctgtagatg gaaaatcagt atcagaagca ttaagtcgag cttattcatt
    20341 tattgcagat attttgtttg aaggacagtt tactggtgaa gattatcgtc aagggatcga
    20401 tgctcgagaa attgcttcgt tgacaggtaa gttattaaaa tctgttactg caggctttga
    20461 tgaaacttat acagaaacga aaaaaaagta agcgaagctc tcaaatatcc tttttttaaa
    20521 cattcgatta cttatcgaga attagattta aagacgcaat tactcgaagc aggttggacg
    20581 ttaccagaaa ttgaacgtac tgactttgac gagttaatgc gtctttttgc ttttcgagat
    20641 gcagtaaaag agcatgagga tgttgagtac tacgataact tcacccaatt ttaggaggtg
    20701 atactttgaa taacgatgac ctaattctga agatgatact agatgaatct ggttttactg
    20761 ccggtatgaa taatgctgtc aaaaagttga actcttttga tgaaacaatc gaaagaaaaa
    20821 gtagaaatag tggcagttca ttaggtagta tttggaaaat atttgctgga agttttctag
    20881 ctagcggagt aactagaatc gtaggagctg gctttgatct aatcaagggt tccataagtg
    20941 gagcggttga tcgagtagat acgatgaata acgctctacg aaatttccaa aatatgggat
    21001 ttagtaattc agaaattatg aagaatatcg gaaagaatgg gcttttatct caaggtattc
    21061 aaggacttcc tactgctttg aatgatgcga taagtcatgt tcaacttctt gcttcttcta
    21121 caggtgattt aactcgttca actcaaatat ttaaagcttt aaatgatgga attcttggtt
    21181 tcggtggttc aactgatcaa gttaatgaag ctgttattca attatctcaa agtttctcaa
    21241 acggaaaagt agacgcacaa acttggaact caatgatcaa cgctcaactt ggacctactc
    21301 tttctgctat tgctaaaaag atgggaatta caatgggaga tctgaaagaa ggtttatctc
    21361 aaggtaagat ttctgttgaa gaattccaaa atcaattaat agaaatggat accaaaggtg
    21421 gcggaggact taaatcatta agtcaaatcg ctaaagattc tactaaggga attaaaacct
    21481 ctatacaaaa tgcaaaaaca gctgttacac gtggtgttgg tgaggtaata gaaggattaa
    21541 ataaagcatt agtagattca gatttaggtg gatttaaggg aattattgat aaagtgggca
    21601 gttcaatgga atcgttctta aaagtaattg ctgcaaatat tcctacagca gtatcatttt
    21661 taagtaattt atttaacgaa attcaaaaat ttggttctgc tttgaaattc atgatgccct
    21721 ttcttgttcc tgcagctacc gcttttggag cgttcatgtt tcaacttaaa ggtataccag
    21781 caataataaa aagcttcaat aattttaaga atgccataat tggcgttgga aattcattaa
    21841 agattatggg ggcaatagct gctgctaatt catttgtttt aattattggt gcagtcgttg
    21901 gtgcaatagc tgttttcggt tactttatgg caaccaatga agagcttaga aacaaggtta
    21961 tatctatttg gaatgatgtg aaagattccg taattggtgt attaaaaaat ataaaggact
    22021 ggggaattga tacttggaat tctgctaaag aaatggcatc aaatgcagtt gagggtgtca
    22081 aagatgcttg gtcaggaaca aaggaatggt tttctaacac ctggaaaggt attaaggatg
    22141 gggccacagg tttatttgat aaaacagtag agacttcaag aaatgcagtc gatagtgtaa
    22201 aaaatgcatg gtctaatatg aagaaatggt tttctgatac ttggcaaagt ataaaagatt
    22261 cagccagaga aaaatggaat ggaatcaaag gttctattat gtcagttgct ggtccattga
    22321 ttacaggtat aaagaatgca tttttacatg ttacttttta tctagagacc ttatggaata
    22381 atttagttga gattggtaaa aacgtctttg agattttaaa aaatgttata cttgcgccgg
    22441 ttttgtttat tacctccatg atttctggtg gatgggaaga aacaaaaaat aatatgattg
    22501 ctgtttggaa taatattaaa gaaagtgcca taaatatttg ggaatctata aagaatatat
    22561 ttgtaagtta ttttacaaat atttattttg ctgcactcaa tatttggaca gggttcaagc
    22621 ttacattgat aaatatttgg aatgaagtgg taaatcaagc taaatcgatt tggttaaaca
    22681 taaagtattt ttttattaat ctttggattg atataaaata ttttgcaatt cagaaatgga
    22741 ttg
//
LOCUS       DAFLVO010000045        22733 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.045, whole genome shotgun sequence.
ACCESSION   DAFLVO010000045 DAFLVO010000000
VERSION     DAFLVO010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22733
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.045"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(26..1957)
                     /locus_tag="L1U99_001820"
     CDS             complement(26..1957)
                     /locus_tag="L1U99_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1212359.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(1975..2889)
                     /gene="pfkB"
                     /locus_tag="L1U99_001821"
     CDS             complement(1975..2889)
                     /gene="pfkB"
                     /locus_tag="L1U99_001821"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBN1212360.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(2886..3638)
                     /locus_tag="L1U99_001822"
     CDS             complement(2886..3638)
                     /locus_tag="L1U99_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBN1212361.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(3797..4006)
                     /locus_tag="L1U99_001823"
     CDS             complement(3797..4006)
                     /locus_tag="L1U99_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212362.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(4017..5344)
                     /locus_tag="L1U99_001824"
                     /pseudo
     CDS             complement(4017..5344)
                     /locus_tag="L1U99_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5480..5635
                     /locus_tag="L1U99_001825"
     CDS             5480..5635
                     /locus_tag="L1U99_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212363.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(5709..6296)
                     /locus_tag="L1U99_001826"
     CDS             complement(5709..6296)
                     /locus_tag="L1U99_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBN1212364.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(6379..7629)
                     /gene="clpX"
                     /locus_tag="L1U99_001827"
     CDS             complement(6379..7629)
                     /gene="clpX"
                     /locus_tag="L1U99_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBN1212365.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(7876..9165)
                     /locus_tag="L1U99_001828"
     CDS             complement(7876..9165)
                     /locus_tag="L1U99_001828"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBN1212366.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(9319..10251)
                     /locus_tag="L1U99_001829"
     CDS             complement(9319..10251)
                     /locus_tag="L1U99_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212367.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(10408..11067)
                     /locus_tag="L1U99_001830"
     CDS             complement(10408..11067)
                     /locus_tag="L1U99_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBN1212368.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(11070..12095)
                     /gene="sppA"
                     /locus_tag="L1U99_001831"
     CDS             complement(11070..12095)
                     /gene="sppA"
                     /locus_tag="L1U99_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBN1212369.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(12108..12398)
                     /locus_tag="L1U99_001832"
     CDS             complement(12108..12398)
                     /locus_tag="L1U99_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212370.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            12807..14612
                     /gene="glmS"
                     /locus_tag="L1U99_001833"
     CDS             12807..14612
                     /gene="glmS"
                     /locus_tag="L1U99_001833"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBN1212371.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(14684..16039)
                     /locus_tag="L1U99_001834"
     CDS             complement(14684..16039)
                     /locus_tag="L1U99_001834"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBN1212372.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(16063..17232)
                     /locus_tag="L1U99_001835"
     CDS             complement(16063..17232)
                     /locus_tag="L1U99_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212373.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(17229..18116)
                     /locus_tag="L1U99_001836"
     CDS             complement(17229..18116)
                     /locus_tag="L1U99_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBN1212374.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(18305..21997)
                     /gene="nifJ"
                     /locus_tag="L1U99_001837"
     CDS             complement(18305..21997)
                     /gene="nifJ"
                     /locus_tag="L1U99_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBN1212375.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            22196..22717
                     /locus_tag="L1U99_001838"
     CDS             22196..22717
                     /locus_tag="L1U99_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBN1212376.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
BASE COUNT         6330 a         4939 c         4044 g         7420 t
ORIGIN      
        1 aaacccagcc tcttcttttt tatttctatg cttctgctac tgcaggagct tttctcaata
       61 aaccataaat cacaccagat acgactgctc cgatagcaat aaacaccaaa tacatgaccg
      121 ggtgactcag taagaataca acgaaaatcc cgccgtgagg agccagtaat ttgattccga
      181 aagctccgac taatccgcca gttaaagcag aaccaataat aaaacttgga atggcacgaa
      241 tcgggtcagc tgctgcaaat ggaatcgatc cttccgtgac aaacgatagt cccatcacga
      301 tgttcgtcaa accagcatct tgatctgttt tgctgaattt attcttaaac aaacgtgtag
      361 caacgaaaat tgccaatgga ggtaccattc ctccagccat aacagaagcc atcacgacac
      421 ttccgccagt tgcaacagtc gtagctaaag ttgctgtacc aaacacataa gcggctttgt
      481 tgattggacc gcctaaatct gccgccatca ttccagctaa taatgcacca agtaaagcag
      541 cattcgaacc actcatactt gtcaagaaac cgttcaatgc atcattgatt gctttcatag
      601 ggacattgac cagcaacatc aagaaaccag taatcagtaa gccaaacact ggataaaaga
      661 ggatcgtttt aattccatcc aatgattttg gtaagttctt gaataattta cgtaaaaata
      721 cgatgacata accagctaag aatccaccaa tcagtgcacc taagaatcct gcaccgcctg
      781 tattagctaa tgcaccagca gcaaatccaa cgatcaaacc agggcggtca ccgatacttg
      841 aagcaataaa tcctgctaat accggcagca tgaaaccaaa tgcagcttgt ccgatttggt
      901 tgaaccagct agcagcttga ttgtaattcc ctagatttga taattgatca tgtggcacgc
      961 caataaattg gtcgatcatg aaagaaagcg caatagcgat tcctccacca ataacgaaag
     1021 gtaacatgtg tgatacgccg ttcatcaaat ctttgtaaat tctttgtccg atagtaccat
     1081 ccgcatttcc ttcttctgaa ctgctttctt ttccatcacc atggaatact ggtgcagtac
     1141 cactaagggc tagattgatc aactcttctg gtttacggat accatcactg acaggacgat
     1201 tgatcagttc ttttccgtca aagcgattca tctctacttt tttgtctgct gcaacgatta
     1261 caccttctgc acgggcgatg tcttcagcag tcaatcggtt tttgattcct tctgaaccgt
     1321 tcgtttcgac tttgatctcc acacccattt ctttcgcttt tttcttcaaa gcatcttctg
     1381 ccatgtaagt gtgagcgatc cctgttggac aagctgtaac ggcaacaacg aattttcttt
     1441 ctggatgagc agaagcttct gcagcttgtg tttcttgttc tgctttttct tctgcttctt
     1501 tttgctcttc agctgtttgg aacaagtctt ggacttcttc tggtgtattt gcttctttta
     1561 attttcctac gaaatctgca tcaatcagca atcgagatag tgctgctaat gcttgcaaat
     1621 gtgtgtcgtt tgcgccttct ggagctgcga tcatgaaaaa cagataagtt ggctgtccgt
     1681 ctaaggcttc ataatctact cctttttggc tttttgcgaa taaaactgtt gcttctttaa
     1741 ctgcactgtt tttcgcgtga ggcatggcga ttccatcacc aagacctgta gaagtttgtg
     1801 cttcgcgggc tagaattcct tctttatatg tttcgatatc ggaaatccgg ccggcatcaa
     1861 acattttttg gaccatttca tcgattgcgc cttttttatc agtcgcttgc aaatccatga
     1921 tcatcgcttc tttgaccatt aaatccttga tattcatgat tatcctcctt gaaactaatc
     1981 aatttttgtg atttcaactt ctggcagcaa ctcatcaatc aattcgcgag ctgccaagtc
     2041 atcagaaaaa gctgttgcgc ttccgcaagc aactccccat ttaaaggctt cgattggatc
     2101 tttcgtacgg ctgtaagccc caataaagcc agcaatcatt gaatcccctg cacctactga
     2161 atttttcaat gggcgaacta atacattcgt tttataagtt ccttgttccg tgaagagcaa
     2221 agcaccgtct ccagccattg agatcagcac attctgtgcc ccttcagcta gtaatttttt
     2281 cccatacgga atgatttctt ctacagattg gaaggttgtg ttgtaaagct cagctaattc
     2341 gtgattgttt ggtttgatca acaacggttt cttaacaagt gcatttttta ggtcatcacc
     2401 tgttgtatca atcacgaaat ctgcaccttt ttctcgaatg atatcaatca gttcttgata
     2461 aaatcctttt cgcaggctag ctggcgcgct tcctgacaat acgacgatat ctccttgtcc
     2521 tactgttcct aatgcttgct tcaactcatc gatttcttca tctgaaatag atgggcctaa
     2581 gccattgatc tcagtttcag tgtctgattt tagtttgata ttgattcttg tatcttcttt
     2641 tacggttgtg aacaaagact ggatttgttc tttttcaagc cacttcgaaa taaattcgcc
     2701 agtgaaccct cctaaaaacc ctagtgctgt agattgagaa tcgatccgtt tcaaaatacg
     2761 ggaaacattg atcccttttc ctccaggtaa cttgaagtct tccttcattc ggttcaaatc
     2821 gcctagtttt aacccatcta cgcgtacgat ataatcaatt gatggattaa gtgttactgt
     2881 gtaaatcatt gtattgcctc cttaattgtt gtcttttcac ggaattcatt aacgaattct
     2941 aatggacaac gctcggttat gatcgtggct gcttccaaag gtgcaacaga ggtgaaggac
     3001 aactggttga atttggtatg atcaatcaat acaaatgtct cttcggaatt tttcatggct
     3061 aaacgtttaa cagctgcctc ttctggatcc ggagtcgtga atccttgttc aagatgggca
     3121 ccgttcattc ccataaatgc tttattaaaa tgaaaatttt ttagttgttc tatcgcatta
     3181 gatcctaaaa cagcattagt tgccagcttt atcgttccac ctaaaataat ggtagcaagc
     3241 tccaaatcaa ctaaatttgc cgcatgttga acggaatttg tcactactgt gatctgtttt
     3301 ccttgcagaa aaggaatcat ttctaacgta gtagagccag cgtctaaata aatgacatct
     3361 tcgtcattaa tggtttcagc tgccgatttg gcgatttgct gtttttcgtg aacgtttttg
     3421 agtgattttt cactcatatt ctgctcaaaa ttcaataatt gctctttctt agctccgcca
     3481 tgaactcttt ctagaaaccc actattctcc agctcttgta aatcacgtct tatcgttgat
     3541 tcagaagcat tcaaaaggtt tacaagatct tgtgatttca cgattttctg ctgttcaagc
     3601 aagtctagga ttttttgtct gcgttcctct gtaagcattt tcacgatcac ctcaatacaa
     3661 ataatagcat attttttttc tactagcaat ataaatcagt caaaaacgtt cataaaaatt
     3721 ataaatcagt caaaaaaaaa taaaaaacca gtcagaaaga ctggtttttt atttttttgt
     3781 ctatcatcaa gccgttttat cgttttttat tttcgcttct tgtttttttc atataaacag
     3841 aagcaggttt tctttcctta tgaagaagat aataataaag tcccatcccg ccaaacatga
     3901 ccaaaaaacc gatgactgat cgaataggaa aattaggaac aaaaaagaga cagacggata
     3961 ataatgatgc cggaaccatt attcgataat agagttgttt atccattttc ttcacctcat
     4021 attttttgta aagtaatcaa ttgttctaat tctcggtaat ctaaaaattg cacacgcaga
     4081 tgctgctcac ctttcttgac atcgaattgg atacttcgcc gctttttctt tattcgtttg
     4141 aaggtaacat cagagagtct atgtttgatt tcctttaacg gtaattctga cagggattct
     4201 gaaggaacat agattcttaa ggataaaaga tactcttgat atttttcatc tgttacctct
     4261 acttctagat attccctaat ataataacaa taagcttcga ttccattatc caaagcaaca
     4321 gtcggatcga taactttata gcacatcatg cgtgatcgat tctcgtcaac ccaaggaaaa
     4381 tacgcctgag catttagtgt tccgcgaaca cgcctttctt tataatctcc ttgttggata
     4441 tcataacttt ttgttacaaa aaatgaagca ttctttttag gaacaggttg catttgtgca
     4501 ttctgatact ggacagattg gatcgtatgg tcagtgtaaa tgtattcaac gaatggcggt
     4561 ttcaataaac cgacaccatt gtcccaagca agatgatcaa acccaagctg gtccctaaaa
     4621 taggattgaa acatttgatt gtttggcttt tgccagttaa aggggtctcg ataaagctgg
     4681 atacatatga cttcgttttc taattccttc actttttcta cttgttggat gtcgagaaaa
     4741 atcggtttag ggatgatttg atgataatag cgactataat acatttccca acacgaagtg
     4801 aaacataaac cttggtaaaa aagatcgtat cctggaaatt ggttgcaatc gactactact
     4861 tccccgtttt gttgtttcat tttaggtaaa tgttcgattt catccttttt ctcaaacaat
     4921 agccgttgag agatctgttt tgtattgtga tagataaact cgctataagc tcgcatatag
     4981 gcgaacaccc catgagcaat catttttttc tgaatgaagt ctcgaatcaa aaattgcttt
     5041 tctttgaaaa cagagataga caatacattt tttatcaata attgattatc ttccaagcga
     5101 aaactacatt cgttctcgtc atttcctaca actaaccaac tttcgtctct taccgatgct
     5161 agcattattt tttcttgaag ctttcgaaga tcatacggat ccgcttgttg tgtgaaagag
     5221 cggataaatg ttggctggat caacagacgt gtcaaaatag cccaatcgct tatttcctgt
     5281 ttttttcttc ttcatttaag tctgtgagct ggatagtcat caataattta tcttcgccaa
     5341 tcattttctc acctctttca aatcttttta taatttaatt ataaccaatg ataaagaaaa
     5401 actaaaactt tatgtcttag aaaccaattt ggacgattac atgatagact aagtaaaaag
     5461 aaacaaagag gtgtttacaa tggggttgaa atttgaacgt acagataatt tagataaact
     5521 tttcgaatca tttgctgtcg atccggaaaa aacagttgca ccaaaagaag agatcgatcg
     5581 atttctaaaa ccacagccac aaaatgaaaa gaaaaaagac aagaaacaaa agtaagttaa
     5641 gctcaaaaaa agacttacca gccaaacttt tatgaaagag tttgactggt aagtcttttt
     5701 tattcttttt atgattcaat tgcttgttcg attgctgccc acgcttcttc ttttccctgt
     5761 tttgtaacgg aagaaaagag aataaacgtg tcattgcgat caaaatccaa cgcttttttg
     5821 atttcgctct catgcttgtt ccatttacca cgagggatct tatctgcctt agtggcaaca
     5881 acaattacag ggatatcata atacttcaaa aattgataca tctggatatc ttcttgagaa
     5941 ggcttatgac gcaaatctac taaagaaacg accgcacgta gctggtctct agtcgttaaa
     6001 tatgtctcga tcatctttcc ccattttgct cgctcagttt tggatacttt tgcataccca
     6061 tatcccggaa catcgacaaa atgtaatgcg ttctcgatca aataaaaatt caatgtctgg
     6121 gtctttcctg gcttaccgga agtacgggct aaattctttc gatcaatcaa tgtgttgata
     6181 aaagaagatt tccctacatt tgatcgtcct gccagagcta tttctggcaa ttgtgtatct
     6241 ggatattgtt ttggtgccac tgcacttatg ataatttcag cttgatggac tttcatggtc
     6301 tctctcctta acaaggtgat gaataaagca agcggctgtc gcaaaagcca aaatgacttt
     6361 tacggcagcc tcttttcatc aacccgcttt tttctctgaa tctttataga ttactgttgg
     6421 ctcaccagac aattcagctg cttcttttgt gataatcact ttttcgatgt tttcatttga
     6481 agggatatca aacatcacat ccatcatgat ttcttcaatg atggaacgaa gtcctcgagc
     6541 accggtattg cgttcgattg cttttttcgc aatggctctc aacgcttcag gttcgaattc
     6601 aagttcggta ttatctagag aaagaagttt ttgatattgt ttgactagcg catttttcgg
     6661 ctcagtcaag atccgtacca gatcatctgt tgtcaatttc tctaaagctg ccataacagg
     6721 taatcgtccg ataaactcag ggatcaatcc gaattttagt aaatcttcag gaatgatatg
     6781 ctgcatgaca ctttcgtctt cagaaagttt ttggttttgt gtaccaaatc caatcgtctt
     6841 ttcgcccata cgattcttca caatcgtttc gatgccatca aatgcaccac ctacgatgaa
     6901 caatatgttc gtcgtatcaa tctgaataaa ttcttgatgt ggatgtttac gtccgccctg
     6961 aggtggcaca cttgcaacag ttccttctag aattttcagc aaggcttgtt ggacaccttc
     7021 gccggaaacg tcacgagtaa tagatacatt ttcgctttta cgcgcaattt tatcgatctc
     7081 atcaatatag atgatccctt tttctgcaag ttccacattg taatcagcag attgaagcaa
     7141 tttaagcaaa atgttttcta catcttcccc cacataacca gcttctgtca aacttgtcgc
     7201 atctgcgatt gcaaaaggta cattcaatgt ttttgctaat gtttgtgcta aaaatgtttt
     7261 accagaccct gtaggtccga tcaagcagat attgcttttt tgcagttcaa catcatctgt
     7321 gttttcttgt gcttgctgat tgacacgttt atagtgattg tatacggcaa cagctaacga
     7381 gcgttttgcg cgatcttgtc caatcacgta gttattcaat acttcaagaa tttctagtgg
     7441 tttagggact tcagtgaatt cgcgtacagc ttcttcataa aattcttcat caatgatttc
     7501 tttacatagg tcgatacatt cattacagat gtagacccct ggaccagcta cgatcttttt
     7561 cacttcttct tgggttttcc cgcaaaaaga acagcgtacg gtctcattgc tacttggatt
     7621 gtcatacatg gtcttcaccc cttaacttgc aaaaagtatg caagaaacta tcaaagactt
     7681 tacagtcttt tactatcata acatagttta gtaaaaagaa aaagtgttta acaaaggatc
     7741 aactgaccta tacctttgca ttttttactc ttaacaaaaa ataaggaact gtgacaaaat
     7801 cgtgtcacag tcccttattt cgaataaaca attttctaga agtagcttct tcagaaatga
     7861 tttattactt gatttctatt ctttcgcttc tgtcgctgta cctgtgatca attcgattgc
     7921 ttttttcatt gtcacatcat gttccagcat atcttctgtc aacacgcgtt tgatttgttc
     7981 gattggcatg ttgtatgttt ctgataattc ttggatttct gcattgattt cttcttctgt
     8041 tgcttgaaga ttttcagcag ctgcaattgc ttcgatcaca agatttgttc ttgtgcgcat
     8101 ttctgcttca ccttcgaatt gtttatgcaa gtcttcttct gtagaaccag ttaattgata
     8161 gtacatttca ggagagatac cttgacgttg catgttgttc aagaattcgt ccattgaacg
     8221 atgtacttca tcatgaacca tcacgtgtgg caattcaacg atttctgcgt tttcaacagc
     8281 catacggatc gctgcttcat cttttgcatc gtccgctgct ttttcttttg tttctactaa
     8341 ttctttgcga tatttttctt tcaattcgtc taatgttgat acttcgtcat caacatcttt
     8401 tgcgaattcg tcatctaatt caggcacttc ttttgctttt acttcatgga ttgtcacttt
     8461 gaagactgct tcttttccag caagatcttc tgcttgataa tcttctggga aagttacatt
     8521 tacatctaga ctttcacctg atttatgacc aactaattga tcttcaaaac ctggaatgaa
     8581 tgagcctgaa cctaattcaa gtgagtaatt ttcgcctttt ccgccatcaa acgcttcgcc
     8641 atctacaaag ccttcgaagt cgattactac tgtatcgcca ttttcagctg cagcatcttc
     8701 tttgataact aattcagctt gtgcttcttg ttcacgtttg atacgtgcat ccacgtcagc
     8761 atctgttact tcacggtctt gtttttcaac aactagatct ttatattgtc ctaattttac
     8821 ttctggtttc actgttactt cagcagtgat tacccagtct tgaccttttt ccatgctttc
     8881 aacatcgatt tttggttgag aaacaggatc gatgccagct tctttgacag cagcttcata
     8941 agcttctggt aatacagcat tcaatgcatc ttcatataaa gcttcttcac cgtacatacg
     9001 gttgaatact tgacgagaaa ctttcccttt acggaatcca ggtacgttca agcttttttt
     9061 cactttatta aacgcagttg ttaatccttt ttggatttcg tcttgcgcaa tcgtaaattt
     9121 taaaacacca tcattcgtgc cttttttttc aaatgttgca gtcatttaat tccctccgag
     9181 tttagaaatt cattttatac atcaaaaacg tttcatgcat acctttaaat agtacactaa
     9241 ccctttcaaa ttgtaaacat attgaatgga tagaatcctt gtttttcata acatttttat
     9301 ctttttcact gataaaatct aatggaagaa gatcatttgc tgcaaaattt tttctctttt
     9361 ttttaaaaaa tcttgttttt catcttctgt accttcatac atcgtttttc ctgtacacgc
     9421 ctctacagtc agttgaaacc agcgcttcgg gtcttcgatg tatgtatcat agacaggata
     9481 aacaattgca gattgcaacg tgaattcttc ttttaacacg gaactaagca gcgcatcttc
     9541 attcccgtaa cgatctgaaa atacacataa ttgctggtaa cttgcctgct gctgcggctt
     9601 tggcagatct tttggtatga ctttgactaa cttttcttca atcgtcaaat agaaaacagg
     9661 atggcattcg ttcaattgcc taagtgtctc cagtaatttt gcccttgcta aaatatggac
     9721 ctctggcgat acaataagtt tactcgctgt ttggataaac tcatgataag gaagctgttc
     9781 gatctcatca atagacgcaa gctgacgtgc aggttccaac gaaggaagtt cctccgattt
     9841 attgtggagt gccttgatct tctgcctctc catttgtccg gataattctt ctgcaaattg
     9901 gattttttca atgacccgct gctcgaaagc ttcataaaaa tctgtacttg ctatcaattt
     9961 tctagcatat aaaaaatctt gtgtactgat taacaagtca aaataaaatt cagcaaactc
    10021 ctcattttga agatactgtt tttcatgcaa gagtgcttgc ttcaatgctt cttttttctc
    10081 gtccaactcg taaagacaaa aaacaagcag gctattagcc tcaaagcttt ctttcaactc
    10141 gtaagctcgt tgaaataatt cttttgcctg ctgatattgc tggtttgcta gtgcttgttg
    10201 tgccactcgc attaaattct catatttttc tggaaaatca atcggcttca cgcagtgtcc
    10261 tcctcttgct catattcagc tcatgttcaa tagtagcaaa acaaaaaaag catgacaatt
    10321 aaaaataact gaagcaccct ctaaaagcta gattttagat ctgactttta gaaggtgctt
    10381 tcaactgtta ctgcttttta ttgctcatca gctgttgact tcctggttga acgctttgat
    10441 cagattgatc gtaacaacac ttgtattagt gaaaaaatcg cccagatgtt gctttttctg
    10501 attaaagact gctggaagat accctaacat cagcaaagga aattttagaa tgaaccggca
    10561 agcaccttct ctaactaaaa cggttgacca gctaagttct tcttcatcaa agctgatgac
    10621 tcgaatacca aagatcattt tcccaatcgt ttggccatga ttgaatttcg tcaataaaat
    10681 aaaatacgct agataaataa gtaaggctgt gaatccgtag agactcagat aagaatctga
    10741 aaaattaagc caacctagat ttttggcaat accaagtgtt aaacgcgtaa tagctccgat
    10801 acacaaaaga tcgaccaaga aggcaaacat tcggataaaa aaacctgcat agaaatactt
    10861 aggaaaatca tttgcttttg gcggttcatt tcttgtgtcc gtatactttt tccatttacg
    10921 ttgtttcttt ttgatttctt cgggcgtcaa aggctctctt tcaaaagagc tcagtacctt
    10981 ttgggaaaag ttggagtcag gtcctacagc aggctgctgt tgcttatctt tttcttgttc
    11041 cttattttca tttgaaagct ctgacatgct tactcacctc cgtaataata cattgctttt
    11101 ggtgattccg ctgtccctag attctcaaga acggataaga tctgactagt ctcagaaggc
    11161 ttcaatccct ggaattctgc tagtttactt cctaaccatg tactagcaaa cccagatggc
    11221 gtggaagaat attctactag ttccgcatct tcaagctgtt gttcctttcg tatagctttt
    11281 aaagcatctt caggaaatcc caattcatcg actaaaccta cttcttttgc ttggacacca
    11341 tcataaatcc ttccatcagc aatttttttg acttcttctt cagatttatt ccgtccctcg
    11401 ctgacgattg ctacaaaacg actatatgcg ctgtcgatat atgcttgaag caccgcttct
    11461 tcttcttttg tctctggtcg cgttcctgaa cccatatctt tcaacgctcc gcttttaact
    11521 gttgtatctt ccacacccag tttttctaga agtcctgaat aattcaatcc tgacatgatc
    11581 acaccaattg agccggtcac tgtttcttct gttgcaaaga ttttatctgc ttgagcagaa
    11641 atatagtagc caccgctagc tgccatgttt ttcatgctga catacattgg gatatcatgt
    11701 tctttacgaa tcgtatccaa tttcttagcg atttccgcac tttcgtagac accgccacca
    11761 ggagaattta cttctaaaaa gatacctttg actgttggat cttcttcaat cgccttcagt
    11821 tgttccataa aatttttatg attgtaacct tcagaagcaa ataaacctga agaccctccc
    11881 gcagcaatcg ttccatctac tgataatttt acgatttttt gcgtactgtc tccctcttcc
    11941 aacacatttg gagctagttc ttcatcccca tataaccaac tgttcaatcc ctcaatttga
    12001 tcgttttcct gaggcttagt caaactagct gaaactaacg aaaccacaaa taatcctgca
    12061 gcaatcagaa ctgctgccca acgtctttta ttcattcttt ctcctttcta atacaagttt
    12121 tttatgacga tcacagtttc tgactgctca gaagtgtcga accgctctgc tttttcttcc
    12181 cgcgcatacc cggaaaacga ctcttttgtt aattcatctt ctaccgtaaa ctcacgagct
    12241 tgagcaactt ccaaggcatc aggtgcgatt tcttggatgc tatcccagcc agtatctaaa
    12301 aatattttcg tatcatctga tacaccagct gatgcttcga atttggacaa ttgttttttt
    12361 aacattccca gtgtcatgat ctcaattttt gaatccattt ttactcctcc tctatccgat
    12421 tactttctat tgtaccgaac tcctgaaaaa gatgatagat aaaaacccat tattttttga
    12481 cataaaaagg acatttgaca aagaatttga tatataccaa tttatttttt attctttttt
    12541 tgttgacaag aacattcgca aaaggttatg attttaaatg tttccagata aaaaacaaaa
    12601 aggaggatag ttataccttt taggatagcg ccaggtctgt gtaaacagat gacgaggaga
    12661 gggtttatcg aaagattcgg cggatggccc tagggactgc actctacaga aaatccacaa
    12721 aaaatgtctg caaagataaa acaaaaggat tttcctgcag ctggaagcat tcatacgaat
    12781 tcattataga aagtaggatg ttttttatgt gcggaattgt tggaatgatt ggattaaaaa
    12841 atgtaacacc aggattgatt gacggtctag aaaaattaga ataccgtggt tatgattcag
    12901 ctggtatctt tgtctcagat ggcacaactg attatctggt caaagcacaa ggcagaattc
    12961 aaaatttgaa aaacaaaata aatattgata ctacaggaaa tataggtatt ggtcatacac
    13021 gatgggcaac tcacgggcaa ccttctgaag aaaacgccca tccacatact tcccaaagtg
    13081 gacgcttcgt gctcgttcac aacggcgtaa tcgaaaactt tgaagaactt aaaattgctt
    13141 atttagcaaa tgaccacttt attggtgaga ccgatactga gattatcgct catctaattg
    13201 aaactttcgc gaaggatact acaacgcaag aggcgttttt aaaagctttg cgggtcatca
    13261 aaggttctta cgctttcgct ttgattgatc ggacagcacc tgatgttatt tacgtcgcta
    13321 aaaataaaag tccactatta atcggactcg gcgatggatt caatgtgatt gccagcgatg
    13381 caatggctat gcttgctcat acgaaggaat tcgttgagat tgaagatgaa gagatggtta
    13441 ccgtcacatc agaaaaagtt attattcaaa attttgcagg tgacatcgta gaacgttctt
    13501 cattcgaagc acaagtagat gcttcagata tcgagaaagg tacctatcct ttttatatgc
    13561 tgaaagaaat cgacgaacag cctattatca tgcgtcgtat cgctcaaaaa tacgtaacag
    13621 aagacaatcg tgtctctctt gatcaaaagc tggtcgatac attgtctgat agcgatcgaa
    13681 tctatatcgt tgcttgcgga actagttacc atgcggggtt agcaggtaaa cagactttgg
    13741 aaaaattgac acagattcct gttgaggttc atttagccag tgaatttggc tataacacac
    13801 ctcttctttc aaaaaaacca ttctttattt tcttgagtca aagtggcgaa acagcagaca
    13861 gccgccaagt gctggtaaaa atcaaccgtc tcggctaccc ttcacttacg attacaaatg
    13921 ttgctggttc tactctttcg cgggaagcat cctttacact gctattgcat gctggacccg
    13981 aaatcgcagt agcatcaacg aaagcttata ctgcacaaat agctgtacta actttattag
    14041 ccaaagctat cggtgataaa aaagaatttg aaacttctct tgtattcgat atcactcatg
    14101 aattgagttt agttgctaat gcgatggaat cggtcatcgc ccaaaaagat tatttagaag
    14161 agttggcaga agtatatctc agcgatacaa gaaatgcctt ttacattgga cgtggtgctg
    14221 actacaacgt ttctcttgaa gctgctttga aattgaaaga aatcagttat atccaggcag
    14281 aaggttttgc cgctggcgaa ttgaaacatg gaacgattgc tttgatcgaa gaaggaacac
    14341 cagtgatcgg aatcatcagt gaagaagtga ctggtgcgca tactcgagga aacctgaaag
    14401 aagtcgaaag ccgtggcgct aaaacactag ttattgtctc agagggatta gaaaaggaaa
    14461 gtgaccagct ggtgctacca actgtccacc cttatctaac tactctaacc acagtcgtac
    14521 cgactcaatt acttgcatat tacgcaacgc tattacgggg attcgacgtt gacaaaccac
    14581 gtaatttagc gaaatcagtg acagtagaat aataaaagaa caaggaccag tgtcagacat
    14641 ctgacactgg tccttgttct tttatttttt atgaaaatat ctcttaatcc agtccgattt
    14701 cttctttgac tactgccgcg attttatcga catagtaatt aactttctca tcagtaggcg
    14761 cttctgccat cactcgaagt aatggttctg taccggaagg acgaactagg attcttcctt
    14821 ctgatcccat ttcagcttct gcctcttcaa tcactttttt gattgccgga acatccatcg
    14881 caccgttttt atcacttacg cggatattca ctaatttttg cggatagatt gttacctctg
    14941 ctgcaagctc tgataatttc ttacctgtct gtttcatgat attcagtaac tgaattcctg
    15001 aaagcatccc atctccagtt gtgttaaaat ctaagaaaat catgtgccca gactgctcgc
    15061 cgccaaagtt ataatcgttt ttgcgcattt cttctacaac gtaacgatca ccaacttgtg
    15121 taacgacatc tttcaaaccg attccttcca ccgctttgtg gaatcctaag ttactcatga
    15181 cagtcgtaac gatcgtatct tttttcaatc gatttttttc tgccaagtat ttagcacaga
    15241 taaacatgat tttatcaccg tcgacaatgt ttccaagttc atccaccgca ataatacgat
    15301 cgccatcgcc atcgaaagct agtccagcat ctgctccttt ttcaacgacc atctcagcta
    15361 aacgttctgg atgggtagag cctacgccgt cattgatatt taacccgtct ggatttgtgc
    15421 ccattgtata aaaatctgtt tcaagatcgg caaacaaacg attaacactt gttgaagttg
    15481 ctccgtttgc tgcatcgaca caaatggtca aaccggaaag gtcaccgttg atcgtttgta
    15541 caaggaattg agaatatttc aataagcctt ctggaaattc ttctacagtt cccaatcctt
    15601 cagctgatgg acgaggcaat tcatccactt cagcatctaa taatgcttca atttctagct
    15661 cttggtcatc tactagttta aaaccatctg caccgaaaaa tttgattcca ttatcttgtg
    15721 ctggattatg agaagcagaa atcatgaccc ctgcgcttgc tttttgcaaa cgtgtcagat
    15781 aagcaacacc tggtgtagag atcacaccta gctggaacac ttcgataccc accgataaaa
    15841 gtcctgaaat cagcgcttct tctaacattt gacctgagat tcttgtatcc cgccctacta
    15901 acacgcgtgg gcgttttcct tcttcttcat gctggcttag gacataacct ccgcaccgtc
    15961 ccagcttaaa tgcaagttct ggcgtaagtt ccttgttggc ttcaccgcgt acgccgtctg
    16021 ttccaaaata tttacccata gttgtaaaat tactccttta acttaatttt ctgaggaatt
    16081 tgttctgctc atttgtgttg attcgcttgt ttctgatgtt tcttctgtac ttgtggtcga
    16141 gctgcttgtc ccagattccg aactggaaga aatggttgtt gtcgatggtt ccgttcctga
    16201 atcagcagat gaaatacttc tactcgtact tgtattttct tgtgtccgac tgctcgtcga
    16261 agcagagcta ctgcttgacg tttgcaacac gggtgtaatc tccacactaa ctgattcggg
    16321 cttgatactt aacccctctt ctactggtat ttcaatttta cgagttgttc gatgattgat
    16381 acctgagaca ttgatcggta cagcaatact gtcaccgatc gatgcaagca aatcgctaga
    16441 gccgcttact tctgcttcca gttttgaaaa actgaaatca tagctttcta ccccggcagc
    16501 tggtgttcct tgctgtatcc cataaagtcg taccgacttg cttggcttga tcgaatcagc
    16561 tctcactgtt acttgcactg gatcagagac gatacttaat acttcccctg ctgcattcag
    16621 cgcctgtatt gggacctcac tattaatccc atcatctgtg accatcgaag cgtccacatc
    16681 agctactact cgtttgattt ctgccaatgt tttgtcacct gtagtgatag agactttttt
    16741 aggactaacg gaagtatcat caagttcata tccagatggt gtgaacgttg aaggaatcaa
    16801 cgtttccaca tcgaaatctt ttattacctt tttctcaacc gttactgtaa tagtcgatgg
    16861 ttcgatcttt gctgtgacag cactgctcaa attttgaatt tttagcggaa cttcatgtgt
    16921 tccttcgccc agcttagtga tatctgctgt gacgcggaac atccgtgtat cttcgtttgc
    16981 ctctgcattc aactgaactc ggtttgcact ggaaagtttg acagtcactg cattttcata
    17041 tccatggata tagtagcgct ttgaatcata agaaatcttg atcggcaccc ccgtaactgt
    17101 ttgattatac gcttcatttc cagaaagcgt atttggaacg gactggccat ttgcattgaa
    17161 gtacagcgca atactgaaca gcaatgcaat aaaactgtaa agaatgcttg tccgtttctc
    17221 ttttgagatc atttgcgatc ccctccctta gtcataccgt ctaggaaaga ttgaatcacg
    17281 tttttcttgt tttttgtttt ctcttcagca attagttctc tacgcaagat tgccaaatat
    17341 tcttgctggg ataagccagc catcagttca ttatctaacg tgatgctgac gtccccggtt
    17401 tcttcagaga caacgatggt aatcgcgtca ctgacttcgc ttataccgac agctgcccgg
    17461 tgtcgagtcc cgaattcttt agggatcaac atactttctg atagaggaag ataggcgctt
    17521 gctactgcga tctttccttc ttttacaata actgcaccgt catgcagcgg tgtattagga
    17581 ataaagatat tgatcagcag ctccccagtg atatctgcat ctaaagcaat ccctgtctca
    17641 atatactcat ctaatccagt atgacgttcg atagtgatca acgcaccgat ttttcgcttg
    17701 gacatatatt ggatggcttt gtcaaaagac aagatcatct tctcatcttc ctgctgttcg
    17761 ctttttgatt gtttgaaaag cgaactgcgt ccaagatgtt ccagtcctct ccggatttcc
    17821 ggctgaaaaa tcacgatagc agctatcacc ccgtacgtaa tgacttggtt catcagccaa
    17881 gacaaggtgt gcagaccaat gatttccgct acgattcgga taacaataaa aatagctaca
    17941 cctttcagaa gctgaatcgc ttttgtgcct cgcagcagtt ggatcagttt gtatacaaga
    18001 taccagacaa ccagaatatc aagtatgttc accaaaaaat tcagagagaa caagtcaccg
    18061 gaaaacattt gctgccaata gtccaaatta aaaagttccc cgatttgaaa tgacataaaa
    18121 agcctctctt ctcttttgag atttcctctc tagtatatca tatgttttaa ttttagaggc
    18181 tgatatgctc gtatttttct tgagaaaaac gcataatttt caagaaaatt gcaagtatgc
    18241 gttttatttt tctctgcaat aaatattttt aaacttcaga gaattattca ttatattttt
    18301 tctgttattt ttcctttttt tcttttgtag cttgttccat ttttttacgt cgttctgctc
    18361 tggcagctct tctagcagct cttctttctt ctgcttcaag gtccgtcgtt ttttcttttc
    18421 tagtcttaac gggtacatcg atagattcct ctggttcaag tcgtttcttg attttttcta
    18481 attctcccgt cagtgcagca tagttgtaaa aacgtgtttt agcgtcgtgg acagtctttt
    18541 caaataaagc ttttgcaaga tttggatttg cgttatctag cgaggaaaag cgaacttgtt
    18601 tcctcatgaa atcaggcata gcagagaaat caggtttttt gtagtccaaa gtcattgggt
    18661 tcttgttttt ttcgaccatt gtagggttat atcgatataa tgaccaataa ccagaagaaa
    18721 cagcttcttt tgcttcttta agcgattctt tcattccgcc aagcaagcca tgtgtgatac
    18781 aaggcgtata ggcaataatc agagaaggac caggatactt ttctgcttct tcaaatgcct
    18841 tgatcgtttg catttgattg gcacctgaag caatttgcgc cacataaaca tttccatatg
    18901 tcatcgccat cattcctaga tctttctttg aagcatactt tccactagcc gaaaatttag
    18961 cgattgccga agctggtgtt gcttttgagg tttgaccgcc agtattggaa tagacttcgt
    19021 tatccaaaac aaggatattc acgtctgctc cgctggcaag tacatgatcg atcccgccaa
    19081 aaccaatgtc gtaagcccat ccgtctccac caatcatcca ttggctgttt tttacgaata
    19141 gatcctttct cttgtatata tcctccagtt cagggaaaat tgatcgttcg ctttcgatcg
    19201 cagcttgcag ttttgctgct ctttgctgcg ttccttcact ctcaaacatg tgtactaacc
    19261 agtcttccat caattctcgt agttcttctg atacttttgg caatacttct ttgattgaac
    19321 ttgccaaagc ctcgcgacga gtctgtgccg ctagaagcat accataacca aattcagcat
    19381 tatcttccaa taaagaattt gaccatgcag gcccttgacc acattcattg gtcgtataag
    19441 gagaagcagg agaagcaccg ccccaaatag aagaacagcc tgtcgcattc gcgatcatca
    19501 ttcgatcacc gaacatttgt gtcaataatt ttacataagg tgtttcgcca cagcctgagc
    19561 aagcgcccga gaattcaaga agcggttgat tgaattgtgt agacaagaca gtattctttc
    19621 ctttgactgg atttgctttt tgtcttaatg tcattgcaaa agcccaattc acagcttgtt
    19681 ctttctgttc ttcataaggc ttcatcacta aagctttttc ttttgcggga caagcctcta
    19741 cacacagacc acaacctgta cagtcttcca ctgaaacttg gatacggtat tttacgccgt
    19801 ctgcgcctcg catttctctc acgataaatc cttctggcgc ttcttccatt tcctcttcat
    19861 ctgctaaaaa tggacggatg gcagcatgag gacaaacaaa ggcacattca ttacacatcg
    19921 tacagcgatc actaatccac tcaggtactt ctaaagcgac gccccgcttt tccatagaag
    19981 ccgttcctaa aggcatttcg ccagttgtca ttccatttgc tacaagtgta ccaacagaga
    20041 gttgatttcc ttcctgtgca ttcactggtt caagtatttc ttgtatataa ccagtgttcc
    20101 ttttattgat tttttcaggc atctccaacg ttctccaatg gtctgggatc gcgacttgat
    20161 gaagcagttc ggtcgtccga tcgattgctt gtatgttttt ttctacgata gccattgatt
    20221 tatgtccata gcttttcagg gcttcttctt ttagcagcgg aagcacctca tcaaaaggaa
    20281 tgatgtcagc taatttaaaa aaagccgttt ccattgccgt attgatccgg cgtcccaaac
    20341 cgacttcttg ggccaatctc atggcattga tcgtatagaa tctaatgtta ttttcagcca
    20401 agtaacgttt taattttaag ggcagatgcg tttctaattg ttcgtcgctc caaagagtat
    20461 tcaataaaaa aatgccacct ggcttcaatc ctttgaccaa gtcatagcta tgcaggtaag
    20521 ctggtgtgtg acaggcaaca aggtccgcat gctcgacaag atacgctgaa cgtatcggcg
    20581 tatctccaaa acgaagatga gagacagtca gaccgccaga ttttttcgaa tcataataaa
    20641 aatagccttg cgcatattta tcggtgtgat ctccaataat cttgatagct gatttatttg
    20701 ctccaactgt tccgtcagat ccaaatcccc aaaacttggc ctggaatgtt tgcggttctg
    20761 tcaaatccag actttccttt ggttccaaag attgataagt cacatcatcc acgatcccta
    20821 tggtaaaccg ttttttgcgt atgcttgggt cttttttcaa ttcatcaaaa actgctgaga
    20881 tttggtcggg agtcacatct ttagacccca atccgtagcg accaccaata acagccgggc
    20941 gaagttcaga atcatataac gcactttgaa cgtctaataa gagaggttct ccacctgccc
    21001 ctggttcttt acttcgatca agaacagcaa ttgtttttac tgtatgaggc aacttttgca
    21061 cgaatgtttc cactggaaaa ggacgataaa gatggatatt caaaaaacct gttttccgtc
    21121 cgtttgcatt caagtaatca atcgtttgtt caatcgtctg tgcaactgat cccatagaaa
    21181 caatgacttc ttccgcatcg tctgctccgt aataagtcac caagtcataa gaagttcctc
    21241 gtaatcggtt gatctctttc atatattttt gaacgatttc aggtaattta tcataatagg
    21301 ggttgatcgt ttcccgttgt tgaaaatgga tgtctggatt ctggttcgta ccactaacag
    21361 tcggatgatt gggattcatc cctcgtttac gaaatgaagc taatttctcc tgattgatca
    21421 gaggagctaa ttcttcatat tccaaaactt cgattttttg aatctcgtga ctcgtacgga
    21481 atccatcaaa gaaattcaaa aaagggactt ctccttcaat agaagcaaga tgggcaacag
    21541 gtgctaaatc catcacttct tgtacactgc tttcagctaa catagcaaat cctgtttgtc
    21601 ttgcagccat cacgtctccg tgatctccga aaatattcaa cgcatttgtc gtcactgccc
    21661 gactagcaac gtggaaaaca cttggcagta gttccccagc aatcttgtac atattcggta
    21721 tcatcaaaag cagcccttgt gaagcggtat atgtagttgt cagtgcacca gttttcaatg
    21781 atccatggac cacaccagct gctcctgctt cggattgcat ttctactact tttactggtt
    21841 gaccgaatac gttttctttt cctgctgctg accattgatc tactaattca gccatggtcg
    21901 aactgggtgt tattggatat attgcagcaa tctcggtaaa tgcataagaa atatatgcgg
    21961 ctgccgtatt gccatccatt gttttcattt ttcgcatgat tcatcatcct tgttcatatt
    22021 ctctcttatt atctgttcca ttataacgta aaacatgcca tttttttctt ttatttataa
    22081 aaatatttta catgtatcta tttgaattgg tcatctaatt tttagacaaa cagtctaaat
    22141 cgttgccttt ttttgtcaga catgtataaa ctataagcga aagaggtgtt ttaacatgga
    22201 tatatcagtg attgatgcaa cgaaaacaaa tacacaaaaa ggaatccttt atggttcatc
    22261 gaatgctcct aaaaaaatgg tcgaattcat caacttagct tgtccgtatt gccgacaatg
    22321 gtttgaagaa tcttatgagc tattagaaga agcagtccaa agcgggcaat tgcagcgagt
    22381 gatcaaattg ttcgataaag aaaaagaaag cttacagcga gggaacgtga tgcaccggta
    22441 tctcacaatc agcgatggcc aaaaagcgat caaagagatc aaacaaatat tcgatactca
    22501 agacgagtgg aaacatcttt ctctccaaga agtagcggat tttgcagtag ataaactaaa
    22561 gctgacagaa caaaaagacg aacagctgag ccaagctgtc atcaacgaag ctgagcaagc
    22621 acatattcga tttgttccaa ctgtcatctt gggtaaagaa atctttgatg aatctatttc
    22681 aatagaggaa ttaaaagaat tgatccaaac aaaataaaaa aataaggagc gtg
//
LOCUS       DAFLVO010000046        22656 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.046, whole genome shotgun sequence.
ACCESSION   DAFLVO010000046 DAFLVO010000000
VERSION     DAFLVO010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.046"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            133..3660
                     /locus_tag="L1U99_001839"
     CDS             133..3660
                     /locus_tag="L1U99_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBN1212377.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="L1U99_001840"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="L1U99_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBN1212378.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="L1U99_001841"
     CDS             7448..7789
                     /locus_tag="L1U99_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1212379.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="L1U99_001842"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="L1U99_001842"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBN1212380.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="L1U99_001843"
     CDS             9146..11566
                     /locus_tag="L1U99_001843"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBN1212381.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11735..12745)
                     /gene="trpS"
                     /locus_tag="L1U99_001844"
     CDS             complement(11735..12745)
                     /gene="trpS"
                     /locus_tag="L1U99_001844"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBN1212382.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            12999..13736
                     /locus_tag="L1U99_001845"
     CDS             12999..13736
                     /locus_tag="L1U99_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBN1212383.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13750..14565
                     /locus_tag="L1U99_001846"
     CDS             13750..14565
                     /locus_tag="L1U99_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBN1212384.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14578..15225
                     /locus_tag="L1U99_001847"
     CDS             14578..15225
                     /locus_tag="L1U99_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBN1212385.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15241..15897
                     /locus_tag="L1U99_001848"
     CDS             15241..15897
                     /locus_tag="L1U99_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBN1212386.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16059..16880
                     /gene="racE"
                     /locus_tag="L1U99_001849"
     CDS             16059..16880
                     /gene="racE"
                     /locus_tag="L1U99_001849"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBN1212387.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16883..18238
                     /gene="rph"
                     /locus_tag="L1U99_001850"
     CDS             16883..18238
                     /gene="rph"
                     /locus_tag="L1U99_001850"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBN1212388.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18239..18757
                     /locus_tag="L1U99_001851"
     CDS             18239..18757
                     /locus_tag="L1U99_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBN1212389.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18864..19364
                     /locus_tag="L1U99_001852"
     CDS             18864..19364
                     /locus_tag="L1U99_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBN1212390.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19644..20564)
                     /locus_tag="L1U99_001853"
     CDS             complement(19644..20564)
                     /locus_tag="L1U99_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HBN1212391.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20729..21742
                     /locus_tag="L1U99_001854"
     CDS             20729..21742
                     /locus_tag="L1U99_001854"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HBN1212392.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21852..22607)
                     /gene="fabI"
                     /locus_tag="L1U99_001855"
     CDS             complement(21852..22607)
                     /gene="fabI"
                     /locus_tag="L1U99_001855"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HBN1212393.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
BASE COUNT         7547 a         3950 c         4824 g         6335 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tcttttttga ttttaaaaaa ggaatagcac agagacgaga taaaaaaaca
    11701 ggcctttaca gcctgctttt ttagagtaaa tgaattaatg gaagtaattg attcccattg
    11761 ctgattttac ttcagaaagt gtttgtgcag ctactttagc agcttcttca ctacctttac
    11821 gtaagatttc cataacagct gaaggatctt tttccaattc ttctcggcgc gcacggatcg
    11881 gtgcaaattc agcttccaat acatcaatga ggtatcgttt gatctttaca tcaccaagtc
    11941 cgccgcggcg gtaatgagct ttcatttctt caattgcttc tttatctgtt ccgaatacat
    12001 ccaagtaggt gaagaccata ttcccttcta cttgtccagg atcttgtaca tggatgtggt
    12061 ttggatcagt atacatactc atgacttttt tctgtaagac atcggcagga tcggagatat
    12121 aaataccgtt tcctaacgat ttactcattt tgccatttcc atcgattcca ggtaatctac
    12181 ccattccttt tggtgggaat acgccttttg gttccaccaa gacttcacca tatgtatgat
    12241 tgaagctttg tacgatttcc tgtgtctgct ctagcattgg tttttgatcc tcaccaacag
    12301 gtacaagatt cgctttgaat gcagtgatat ctgctgcttg agaaacagga tagataaaga
    12361 atcctgtagg cacgctttca ccgaattttt tttgttcgat ttctgttttg acagtcggat
    12421 tgcgccgaac gcgtcctacg ctgactaagt tcaaataata catggttaat tcagctaatt
    12481 ccggaatttg tgattggata aataaagtag attttgcagg atctaatccc acggctaaat
    12541 agtctaaagc aacttgcaag acatttgatg aaaccttctc aggattttta gcattatctg
    12601 tcagtgcttg catgtcagca atcatgacaa acagttggtt gtcttcatct gcctgcatag
    12661 ccactcgggt ttttagagaa ccgacgtaat gccctaaatg cagcttccca gttggtcgat
    12721 ctcccgttaa aataatattt ttcaaaaaag acacctcttt acgatttgta agtctgagca
    12781 cttaatatct taccgttttt cctgaaaaga aacaacagtt cctaaggaaa aaacaaggaa
    12841 agaggataaa ataactaata gattagaaat ggaagaaata tttatgggag aataaacgtt
    12901 ctaagaaact ttacaaatta ctaaactatc agatataatg tattttatta tacatcttta
    12961 aaagaaatct tactaaataa taatgggagt gtaattctat ggcaatgatt aaatttgatc
    13021 acgtggataa atattatggc aagttccacg cattaaaaaa tatcaatctc gaattcgaga
    13081 aaggagaagt tgtcgttgtc attggtcctt ctggttcagg aaagagcacg atgcttcgct
    13141 gtatcaatgg attagagacg atctcttcag gtaagctgct gattaatgat actgacttgc
    13201 atgataaaaa gacaaaactg acagaagtcc gaaaaaacat cggcatggtt ttccaacatt
    13261 tcaatttgta cccaaataaa actgttctgg aaaacatcaa attagcacca atcaaagtgt
    13321 tgaagcaaga ccaggcaact gcagtcaaaa acgcggagaa atttttgaaa actgtcaata
    13381 tgttagataa gaaagattct tatccttcca tgttatccgg gggacaacag caacgggtgg
    13441 caatcgccag aggtttagcg atgaatcctg agatgctgct gtttgatgaa cctacttctg
    13501 ctttggatcc ggaaatgatt ggtgatgtat tagacgttat gaaaaaattg gctcatgacg
    13561 gtatgtcaat gattgtcgtg acacatgaaa tgggctttgc caaagaagtg gcggatcgtg
    13621 ttatcttcat ggctgatgga gaagtattgg aagacagcag aaatgtgaga gactttttcg
    13681 aaaatccaaa tgaagtccga gcacagcaat ttatcagtaa agttatcaat cattgatagg
    13741 aggaaaaaga tgcgcaggtt aaaaaaaata cgcctgattt tccttttagg cattgctttt
    13801 cttgcactag ccggatgtaa aggaaatggg ttggcaaatg aagatatttt agagcgaagc
    13861 aaatctacca atgaaatcat ctggggtgtc aagtatgata ctcgattatt tggaatgatg
    13921 gatattgaga gcagaactgt acaaggattt gatgtagata ttgcaaaagc aatcactaaa
    13981 aagatccttg gtgacaatgg aaaaacagaa tttgttgaag tcacttctaa aactcggatt
    14041 ccattattga aaaacggaaa tatcgatgca attattgcaa cgatgacgat cacagatgaa
    14101 cgaaaaaaac aggttgactt ttcagatgtc tatttcgatg ctggccaagc tttgttggta
    14161 aagaaaggaa gccaaatcaa aagtgtagat gatttgaatg cttctacaac ggttctagca
    14221 gtcaaaggtt ctacatcggc tgcgaatatc cgacagcatg caccagatgc aaaaatttta
    14281 gaattagaaa actatgcaga agcatttact gctttacaat ctggtcaggg agacgcgatg
    14341 actacggata atgcgatttt gttagggatt gcagatgaaa atccagagta tgagttagtt
    14401 ggtggaacgt ttactaatga gccttacggg attgcgatca acaaagggca agaaaacttc
    14461 ttgaaagctg ttaaccaagc gctagaggaa atgcatgcag atggcacata cgataaaatc
    14521 tatcaaaaat ggtttccaaa tgaaactgaa ggaaaagtag agtaaggggg agaggcaatg
    14581 agcgaattga tacaaactta tggaccaatc tttgtcgacg ggttcaagat cacattgttt
    14641 tcgagtgtct tagcacttgt gtttagtttg attatcggaa cgttaatggc aatcttccaa
    14701 ttatcaaaga ataaagtagt gagcgcctta gcaaaggcat atgtagaatt ttttagaaac
    14761 attccattat taatcatcgt gatgtttttt tatgttgtcg taccgattta ttggtttaat
    14821 ctagatggat tccaagcagg tacgattgga ttaacgatct atacatctgc ttttattgct
    14881 gaaacagtac gttcagggat tcaaaccgta ccaaaaggtc aaacagaagc aggactatct
    14941 tctggtttta cctattcaga aatcatgcgt tatattgttt taccgcaagc attcaaaatc
    15001 gttatcccgc cattaggcaa ccaatttatc aacctcgtaa aaaactcatc tattttagca
    15061 atcgtagctg gtttagattt gatgtatcaa ggagacttga tcgctagtga aacattcaat
    15121 accttcgata cgtatatcat cgttgggtta ttttacttag ttatcacgct accgttatct
    15181 tacttaatgg tttatcttga gaaaaaatgg gcggttcgtt catagaagga ggggaaatac
    15241 atggatttta gcggcgcttt ttcatggatg aatatccgtt ttttattgga aggattaaag
    15301 gttactgttg aagtttcatt gttttcgatc atttttagtt tcttgatcgg tggtctgaca
    15361 ggtgtgattc gttttgcgaa tatccctttc ttttccaaaa tccttggtgt agtgattgat
    15421 attatacgga atcttccatt attattgatc attttcttca cttactttgc cttacctcaa
    15481 atcggcattc agatgaacat cttctggtcc gctgtcgcag cattaacgat ttttgagtca
    15541 gctatgttgt cggaaatttt ccgagctgga ctcaatgctg ttccaaaagg acagatggaa
    15601 gcaggattat caacgggact gacttatgta gaatcgatgc gaacgatcgt gttaccgcaa
    15661 gcatttaaat caatgatccc ggcaattgtg agccaattga tttcactgat caaagatact
    15721 tcattagcag taatcatttc tttacctgaa ctttctcatc aggcacgtat tatttatgga
    15781 cagaacacca attatgtgct tccgatgttc atcatcatga cacttatgta cttcgtggta
    15841 tgttacgcgc tttctctgct ttccggttac ttggaaaaga gacggtacag ttattaatag
    15901 atgattcttt tagcggttgt ggcaaactaa agtcacaacc gcttttcctc tttccattcg
    15961 aaaaaaagag atttcgattg ttttaagcaa gtaagagcac ttgaaaattc acgctaaaaa
    16021 gtacacaata gggaggatag aatttattga aaaaaaggat gatacgattg acagataatc
    16081 gccctatcgg atttattgat tcaggtgtcg gcggcttgac tgtagtaaaa gaagccctga
    16141 aacaattacc gaatgaaaat attttatttg taggagacac agcacgctgc ccatatggcc
    16201 ctagacccgc ggaacaggta atccagtata cttgggaaat gacggattat ctggtggagc
    16261 aaggaatcaa gatgctggtg atcgcctgca ataccgcaac tgcggtggct ttagaagaaa
    16321 tcaaagctgc tctttctatt ccagtcatcg gtgtgatcct tcccggtact agagcggcag
    16381 taaaaaaaac acaaaataaa caagttggca ttatcggtac gattggtacg gtaaaaagtc
    16441 aagcttatga aaaagcactg aaagagaaag taccagaatt gactgtgaca agtcttgctt
    16501 gtcccaaatt tgtttcagtt gtcgaaagta atgaatacca ttcatcggtg gcgaaaaaaa
    16561 ttgtggcaga aacattagct cctttaacca ctaaaaaaat cgatacattg attttgggat
    16621 gcacccatta tccattatta cgccccatca ttcaaaatgt aatgggagaa aatgttcaac
    16681 tgatcgattc tggagcagaa acagtaggtg aagtatctat gctgttagat tatttcaatt
    16741 tgagcaattc accgcaaaat ggtcggacat tatgccagtt ttatacaact ggctctgcca
    16801 aacttttcga ggaaatagct gaagactggc ttggaatcgg acacttaaat gtagaacata
    16861 tcgaattggg aggaaaataa ggatgcgtca tgacgggaga aaagcccaag agcttcgcaa
    16921 actggagctt caaacaaatg ttttcaaata tccagaagga tcggtagtga tccgttttgg
    16981 tgatacaaca gttatttgtt ctgcaacaat agaaaattct gttccccctt ttttgagaga
    17041 aacaggaaca ggatgggtga cagcagaata tagtatgctg cctcgagcaa cgagtacgag
    17101 aaatcgtaga gaaagcagca aagggaaact ttctggtaga acaatggaaa tccagcgtct
    17161 tattggtcgt tccttgcgtg cagtagtaga cttggaaaaa ttaggagaac gtagtatcat
    17221 cgtagactgc gatgtgatcc aagcggatgg cggtactaga acagcaagta tcactggggc
    17281 atttgtggca ttgaaattag ccattgaaaa acttttaaga gaaaaagaat tgtcagaaga
    17341 tccaataaaa gaacatcttg ctgcagttag cgtaggaatc ttaccagatg ggacttgcgt
    17401 cacagatttg gattaccaag aagattccgc agcacttgta gacatgaatc ttgtaatgac
    17461 agaatctgga aaattcgtgg agattcaagg aactggagaa gaagcaacgt ttgatggtga
    17521 acagttgaat gaaatgctct tttttggaaa aaacgcgatt gaagatttga tcaaagagca
    17581 aaaacatgct ttgctaacag agtttgctca aaatgatgag cggatagaag aaacaaaaac
    17641 aatcatcatt gcgacaagaa atccaggaaa agcagaagag tttcgaaata tgttcaaaga
    17701 agcgggatat catgtaaaaa cattacttga ctatcctgaa ttgccagatg tggaagaaac
    17761 tggcagcaca tttgaagaaa atgcccgatt aaaagcagaa acgattgcac aattgcttga
    17821 tcagccagtc ttagcagatg attcaggttt gaaagtggat gctttaggcg gtatgccagg
    17881 aatctattct gcacgttttg caggggaaca aaaaagtgat gcggggaata acgccaaatt
    17941 attatatgaa ttgacagatg tgccggatga aaaaagaaca gcacaattcc attgtacgtt
    18001 agtattcgcg gcacccaaaa aagacagcct tgtagtagaa gcggaatggc ccggtcgagt
    18061 agcccgtata ccatctggcg aaaatggctt tgggtatgat cctttattta tcccagaagg
    18121 taagaaacaa acagcagcag aattatcgag cgaagaaaaa aacaagatca gtcatcgggc
    18181 tcaagcaatg aaaaaattga gtgccgagtg gaaacaatgg ctggaaggag agagatagat
    18241 gcggtattta gtagtaagtg ataatcatgg agacagagat atcctcgttg acttagtaga
    18301 tcgttatcgt tctgaagtgg atatcttttt ccattgtggt gattcggaat tagaagcttc
    18361 tgacccatta tgggatacat tccaagtggt tcaaggtaat tgtgattatg gaccaggatt
    18421 cgaacagaaa aaagtgatcc aaactggtca ggatacagta ttcatgactc acggtcattt
    18481 atcgaatgtc cgatttggtt tgacacagtt agcaatcgaa gctcgagctg caactgccga
    18541 tatggtgttt tttggtcata cccatcaaat aggctgtgag atggatcaga aaatcctgtt
    18601 tttgaatcct ggtagcattt ctcagcctag aggcccgatc caaatcccat catatgctct
    18661 tatcgaaagt ttagatgacc aaatttctgt tcaatactat aaccgtgccc atcaggcagt
    18721 tgaagagttg gccttttctt tttcgagaga gcgctgaata aaaaaactct aatttttaat
    18781 aaaaataagc tttattttat gaattttgca tccggtttcg gtaaaatagt agtgttgaat
    18841 gaaatagaaa tggaggccat cagatgattg gacctatagt aagagaaatg ctgctggaaa
    18901 atcaggaaac gtttttgatt cctgcagaaa atgtggcaaa tgttatgtat catcatccat
    18961 tgtcccatgg tttacttgtg ttatcgaagg tcggttattc caaaattcct gtattaggaa
    19021 aagatgatca ctttgtagga ctagtaagtt tatcagatgt ggtcaataaa atgattgact
    19081 tgcaaacaat cagcatggac ccgttagaag gactaacggt tgctgatgtg acagaaacag
    19141 atgttccgac aattgatgaa aattgggaac tagaagaagt actccatttg ttagtcgatt
    19201 cgcctttttt accggttgtc acagaagatc ggattttcaa aggaatcatt acaagaaaag
    19261 agctgcttaa agccgtaaac ttcatggtgc atgaattaga acgtcgtaat atattgtctc
    19321 cgaaaatcga agaattaaaa gaacaaatcg atatcgtgag ctaaagaacg agaaactaaa
    19381 agataatcaa aaaataagta gaaaaaacag cgtaccagtt ttgactttat cttgaaaaag
    19441 aggctgggac aaaagcgttt aactccaaga aataagaagg aattcacgaa aattgctttt
    19501 caaatttttg tgaatttcag cttatttccg aaggagttgc ttctgcttcc gccgtttata
    19561 cgtgtttaga gcgtgggaca aaagtgttct ttacttttgt cccacgctct ttttagtgag
    19621 attcgttgca tcgtttgtcc aaattatttt ccgacagcaa ttggactgtt cggaatcgtg
    19681 aaaccagaag ctgtcaattc tttgacatag gagctcaaga actcttcttt taaggcatat
    19741 tgttttccgt tcaatgcgta gcagaccgta cgaatcgcaa aattgctgtt tccaagatcc
    19801 actaatccaa agatagaagg ttcagtttgg agctcttctt ggtatttttc agctaatgta
    19861 cgatttactc gatcaatgat ctcatagatt ttgtcatatc cttcttcagg aacaatccga
    19921 atatctaaaa gtacttgcat atttgcacga gagagattgc tgatcgtggt gatgtttcga
    19981 ttcgggatga aatggacagt accatccgtt gctttcagct gaagggtacg gataccaaca
    20041 gatacgacgg ttccttcaat cgttaagttt gctagcttga tgtagtcccc aacatccatc
    20101 tgttgttcca tgataataaa aaatccggta ataacatcac tcatgaaccc ttgggcacca
    20161 agaccgattg ccacacctgc aattccggca ccagccaaaa gtgatccgat cggcacaccg
    20221 atagcagata aaattgcata gataaaaaag aaaccaaggg tataatgaaa aatagtattt
    20281 aaaagactat gtaaagtctt taagcggctc tcgtttagaa tggctttttt agaatactga
    20341 ttaaaagact tatcaatcag atattttccc acacggtgaa gaatccaaaa aaggacgatc
    20401 aaaaaaatca gatataaact tttttggata aaggcagcca aaatggcgtc ccaatcaatc
    20461 ccgtcccaaa accgctgaaa cgcatttact ttgctgacag cttgatctgt caatgtctcg
    20521 ccagaagagt ctgtcgtacc ggcagttgct aataatgaaa acataaaatc ctcttttcta
    20581 aaatttgatt ctttctgtat tgtaccaaga agttttcaaa aaaggaaata gcaaaaataa
    20641 ctataatgaa ggaaaaaagc tgaaaataaa atgacaaata atatggataa tgataaaatg
    20701 tggagaaaat aacgaaggtg gtaagtatat gcaaatcgat tggaacaatc taggtttttc
    20761 ttatatcaaa actccttggc gttttattgc caaatggaaa gacggacaat gggaagaagg
    20821 agaattgaca gaagataatt acctgacgat tcatgaaggc tctccagcgc ttcattatgg
    20881 tcagcaatgt tttgaaggtc taaaagctta tcgtcgaaaa gacggcaagg tcaatctctt
    20941 tcgacctgaa caaaatagtc gacggatgaa tcaaagtgct agacgattgc tgatgccaat
    21001 ggtccctgaa aagatgttcg ttgatgctgt caagcaagtg gtaaaagcaa atgaagattt
    21061 tgtgccgccc tatggaacag gcgctacatt atacttgcgc cctttactga ttggggtcgg
    21121 tgaaaacatt ggtgtccatc cagctccaga atatttattt gtcgtcttct gtacgccagt
    21181 aggagcgtat ttcaaaggtg gactaaaacc aacgaatttt attgtatctg attacgatcg
    21241 tgctgctcct aaggggactg gtgcagcaaa agtcggcgga aattacgcag cgagtttact
    21301 tccaggaaca gaagcaaaag aactggatta ctcagattgt gtttatcttg atccagccac
    21361 acatacgaaa atcgaagaag taggtgcagc aaatttcttt ggaattacaa aagacggaaa
    21421 attcatcact ccgcaatcgc cctctatctt accaagtatc acgaaatatt ccttgttgca
    21481 gttagctgaa gaacgactag gactgcaagc aattgaagga gatattttca ttgatgatct
    21541 agatcaattt gcagaagctg gtgcatgtgg tacagcggct gttatttctc caatcggtgg
    21601 gatttatcac aataacaatc ttcatgtatt ttatagtgaa acggaagtag gaccagtaac
    21661 aaaacggttg tatgatgaat tgacaggtat tcaatttgga gacatagaag caccagaagg
    21721 ctggattgaa gtcgtggaat aatttcaaag taatgagttg aaaaaaacgt aaaaagaaaa
    21781 aatcaggaag agactttaaa aagttttttc ctgattttta tatgttttac tttaaagaat
    21841 gcaacaaaag tttatgaaag atggacacct ttgtcaacgt agataatatc accgatgatt
    21901 ccgctggaaa gtgggctgat taagaaagca caagcattac cgacttcttc gatcgtcaca
    21961 ccttgctgat caggcgtacg agattcagat aactggatca gtttttgata gtctttaaca
    22021 cctgtgacag ctaatgtttt gattgcccca gctgagattc cattgacccg aattccttta
    22081 ggcgagaact cagctgccaa ataacggata gcagcttcaa gagaagcttt cgcaataccc
    22141 atcatgttat aattcgggat tgcgcgttct gaacctagat aagtcatgct aacgatcccg
    22201 ctgtttggtg caagaaacgg ttgtgcgtat tttgatacag caattaaaga gtagctgctg
    22261 atatcttgag ctaattgata gccgtctctg gaaatatcag acacatttcc ggacaattct
    22321 tctttgttgg cgtaagcaac tgcatggaca aggccgtgga tctccccagc atattcaccg
    22381 atggcattca ttgctttttc gatgctttcg tcgctagaaa catcacattc tacagtgaat
    22441 gcttcttcgc cgaccaattt gactaatgat tttttcattc gttcattttg gtaagtatag
    22501 ataatttctg ccccttgttt caacattgct tcagcacaac cccaagcaat gctttttttg
    22561 ttagcgacgc ccataatgac gatttttttt ccttctagaa atgacataat gactctcctt
    22621 tgtttctgat aaaaatttga tagtcgtaaa aaaata
//
LOCUS       DAFLVO010000047        22464 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.047, whole genome shotgun sequence.
ACCESSION   DAFLVO010000047 DAFLVO010000000
VERSION     DAFLVO010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22464
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.047"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            144..542
                     /locus_tag="L1U99_001856"
     CDS             144..542
                     /locus_tag="L1U99_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBN1212394.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            526..1220
                     /locus_tag="L1U99_001857"
                     /pseudo
     CDS             526..1220
                     /locus_tag="L1U99_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
     gene            complement(1814..2701)
                     /locus_tag="L1U99_001858"
     CDS             complement(1814..2701)
                     /locus_tag="L1U99_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBN1212395.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2886..3725
                     /locus_tag="L1U99_001859"
     CDS             2886..3725
                     /locus_tag="L1U99_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBN1212396.1"
                     /translation="MIRIIRLIGSVLIVFVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3921..4895
                     /gene="sgrA"
                     /locus_tag="L1U99_001860"
     CDS             3921..4895
                     /gene="sgrA"
                     /locus_tag="L1U99_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HBN1212397.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSEISTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5193..5549
                     /locus_tag="L1U99_001861"
     CDS             5193..5549
                     /locus_tag="L1U99_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212398.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5552..6709
                     /locus_tag="L1U99_001862"
     CDS             5552..6709
                     /locus_tag="L1U99_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1212399.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6735..7175)
                     /locus_tag="L1U99_001863"
     CDS             complement(6735..7175)
                     /locus_tag="L1U99_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBN1212400.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7335..7841
                     /locus_tag="L1U99_001864"
     CDS             7335..7841
                     /locus_tag="L1U99_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBN1212401.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            8009..9922
                     /locus_tag="L1U99_001865"
     CDS             8009..9922
                     /locus_tag="L1U99_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBN1212402.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9927..10928
                     /locus_tag="L1U99_001866"
     CDS             9927..10928
                     /locus_tag="L1U99_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1212403.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(11130..11336)
                     /locus_tag="L1U99_001867"
     CDS             complement(11130..11336)
                     /locus_tag="L1U99_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HBN1212404.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11982..12830)
                     /locus_tag="L1U99_001868"
     CDS             complement(11982..12830)
                     /locus_tag="L1U99_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBN1212405.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12829..13896
                     /gene="gnd"
                     /locus_tag="L1U99_001869"
     CDS             12829..13896
                     /gene="gnd"
                     /locus_tag="L1U99_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HBN1212406.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            13898..14899
                     /locus_tag="L1U99_001870"
     CDS             13898..14899
                     /locus_tag="L1U99_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBN1212407.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALIERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14896..15180
                     /locus_tag="L1U99_001871"
     CDS             14896..15180
                     /locus_tag="L1U99_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBN1212408.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15213..16010
                     /locus_tag="L1U99_001872"
     CDS             15213..16010
                     /locus_tag="L1U99_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBN1212409.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            16024..16857
                     /locus_tag="L1U99_001873"
     CDS             16024..16857
                     /locus_tag="L1U99_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1212410.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16875..17732
                     /locus_tag="L1U99_001874"
     CDS             16875..17732
                     /locus_tag="L1U99_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1212411.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17754..18263
                     /locus_tag="L1U99_001875"
     CDS             17754..18263
                     /locus_tag="L1U99_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1212412.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18300..18701
                     /locus_tag="L1U99_001876"
     CDS             18300..18701
                     /locus_tag="L1U99_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212413.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18813..19166
                     /locus_tag="L1U99_001877"
     CDS             18813..19166
                     /locus_tag="L1U99_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212414.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19200..19643
                     /locus_tag="L1U99_001878"
     CDS             19200..19643
                     /locus_tag="L1U99_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBN1212415.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19660..20745
                     /gene="uxuA"
                     /locus_tag="L1U99_001879"
     CDS             19660..20745
                     /gene="uxuA"
                     /locus_tag="L1U99_001879"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBN1212416.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20738..21451
                     /locus_tag="L1U99_001880"
     CDS             20738..21451
                     /locus_tag="L1U99_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBN1212417.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(21658..21807)
                     /locus_tag="L1U99_001881"
     CDS             complement(21658..21807)
                     /locus_tag="L1U99_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212418.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            22203..22403
                     /locus_tag="L1U99_001882"
     CDS             22203..22403
                     /locus_tag="L1U99_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBN1212419.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         7746 a         3451 c         4641 g         6626 t
ORIGIN      
        1 tccatacatc cattgtactc tgagaaatca cacaatatcg aaacaaattc cgttaggaat
       61 gtgttattca ataaatttta taatctagaa acattttgaa taaaaactat tagacaaatg
      121 atattttacg aggaggaaca gagatgacga tctttgaaac ggttgtaaca gatgttggta
      181 tagaagcaga agtattcagg aaagaaaaaa taatgatttt atttggagat gaagcaccgg
      241 aaacattaac agattattgt tataagattg aattgaatca ggtaagaaaa gaaataactt
      301 gtgatatgaa gctctgtttt gataaacaaa tgtatgtaat cacagcagta ggagatgttg
      361 tccaaactaa tttgaatgaa ttaggacata tcacgataaa atttgatgga tctcatgagc
      421 cggaacttcc aggaacaatg tatgtagaag ataaggaaat gccgcattta agaaagggga
      481 caatcattaa aatcgatcaa gaggatcaga atgggggaaa gctatatgga aatcatgctt
      541 gatacagcaa atacaaaaag tatttattct tgtcaacagt ttttgaattt aacaggcgta
      601 acaacaaatc ctacaattct gaaaaaagaa ggagcgtcaa acttcttctc gcatatgaaa
      661 gaaatcaaaa aaataatcgg acagattcct atccatattc agacaatagg aagaacggaa
      721 gaagaaatga tagaggatgc tcgagttatc atagaagaac tgggaaaaga tacgtttatc
      781 aaggtgccgg tgaatcaagc aggccttcaa gcgatcaaaa agttgaaaaa agaaggttat
      841 ttgattaccg gtacagctat ttacacagaa ttacaagggt atttagctat taataatgga
      901 gcagattata ttgcacctta ttataacagg atgcaaaatc aaggcattga tgctatgaaa
      961 gtgattgatt cgttgcggac tgagatcgaa cgtacgcaaa gaccaacaaa aatattagca
     1021 gctagtttca aaaattgtga acaagtcact acagccattc gatctggagc tcagcgataa
     1081 cgttaggtaa agagctacta gatcaagtat tagagatgcc ctcgattgat aaagcagtga
     1141 ggggcttcca agaagattgg gtgcaaactt tccaagcaga aacgattggt gaactaaaaa
     1201 aggtcgctga ttacttctga atcaatttct ccataaaata aacgatagcc ttctcgaaaa
     1261 ctcgaggagg ctatctgacg attcaatatt cattaattta aagtttgggt gactattact
     1321 aactattact tatttctcat ttaaacgatg tattccctaa cctctaatac atccttgtaa
     1381 ctctgaagtt acgccagttt tgaataaatt tcataaaaac aaatgaaaag tgtcgcataa
     1441 aaatatcttt cgtgtttctc tagtataaca gaataagaag aacaagtcca gaagggatat
     1501 ttttagtctt ttttaaaata acttttcagt cgagtttgag tttatgatag ttgtttttga
     1561 agcgatacgg caagtgaaaa aatagggaag catgaaagaa tctacttaat ggcgcattga
     1621 ttcatgtgat agaaataaaa aactttttta aattatatcc tcatgattgt aacaaatcca
     1681 gtgatttgtt ttggtacaaa taaaaaaagg ccccgatgaa gttgtggcaa aagtggtttg
     1741 cctcaaaaat aagaaggaat ttccaaaaat cacttctcaa attttgccac atccccaatt
     1801 gggtcaaatt tgtttatttg aatatatttt ttacataagg atctttaata gttacattgt
     1861 cttttttcat cactttacgg attgttttat ccatgaattc cgtatcaaga gtttttgctt
     1921 cggtagcaat tttttctagc tcagatttgt atttgtcttt attagaacct ttatcctgtt
     1981 tttttaccat ttttactaga taatagcttt gctgataagt cgttggatct gttacaggaa
     2041 tgatatcaga aacttccccg ttttttagtt taaatgctgc tttttttact tcagtaggaa
     2101 tctctggatt ggttgaatca aaattcattt ttccatcagt ttcctttaat gttttatttt
     2161 ttccataagc ttgaacaagc ttggagaaat tttctccttc atttgcttct ttttttgctt
     2221 tatctgcttc ttctttagtc gaaaatagaa tgatctgtgt actaacttct ggatagaatt
     2281 ctttccaagc agtgtctaga tctttatctg ttaattttac attggctttc aaaccgtatt
     2341 ggaaagccag catctgttta aagagtttct tatatgtctc ttctgtttgg ccaactgctt
     2401 ttaattgttc cttgtagttt ggaccgagtt ttttgatttg ttcattatat tcttttgtta
     2461 cttcctttga agaaatctct tttccgtata catcatcaaa tgctttgaag acaatcattt
     2521 tttttaatag tgtttgatta tttgatttaa cttttgggtt atcataaaaa tcctgaactg
     2581 taagtgttcc acctttaaac gttgcaatcg tttcattgga cttgctacaa cctgagaata
     2641 gtaaaattgc acatgctgaa aggcacataa ttagtagttg ttttttcaaa aaatttccca
     2701 tcctttcctt attaaaaaca gtctaacaga agaattaggg agacagtctt tcattttcgt
     2761 aaggttgctg tagatattct tagttcgtaa aaatctattc tctctatgat ggagaacatt
     2821 tacatagttt tcacgagaca agaaagaaaa gggttgttaa acttaatata aaggagggat
     2881 gaaagatgat caggattatt cggttgattg gatctgtttt aatagtcttt gttggttttg
     2941 ttttaggaat tcttgtcaat aatgcacttg cggatatgtt tattggaaat agtgaatgga
     3001 ttggagcaat tgccggtacg gtcggacatt tagctgtttt tttactagct ttatttcttg
     3061 ctagtaaggt cgaaggaaaa agaatagaag attatggtgt ttctgttcga ggaaaagact
     3121 gggggtattt agcgggaggt ctcgttgttg gaattggagt gtttctgctt attactagtc
     3181 cattatattt gacgggggcg tatcggttag attcaggaaa cgcaaacatt gtgccgctga
     3241 taacgagttt tattttattt attgcagtgg gggcatcaga agagctttta ttccgtggct
     3301 tttttcagca tcagatgctt agatttggtc cgttaatagc aatgattgga tctgctgcat
     3361 tatttgctct tttgcacgga ttgaatccta acatgacatt tctggcagtt ttcaatatct
     3421 ttttagcagg ttgctttttc agcgcactta tctacagtac aggaagttta tttacggcta
     3481 ttggtgctca tattacttgg aattggacac aaggagctat tttgggtata ccagtcagcg
     3541 gaacgcaaga acaaggtttt ttctccactc tgatccaatc gcaaaataca ataattactg
     3601 ggggaaactt tggggctgaa gcatctatat caactacatt attcttgtta gtcttgattg
     3661 ttggtttgtt actctatgca tataaaacaa agcggatgaa gaaatacact gctgtttatc
     3721 aataaaagat gaagaaagca aggctgatat cggtcttgct tttttaagtc tgtcattgat
     3781 taaacgaaaa agtaaacaaa ttcaagcgaa tacacgacat cttttgttag attttcacaa
     3841 ctgactgtcg tgttctcatc attttcattt tatataattc ctttatcaaa tagaaggtaa
     3901 ttatatggag agtgatagaa atgaagaaaa cagcgaccgt attatttgtt attcttgggc
     3961 tgagtataat tgcagcaatg attggaatca gtacttctgc aaatgaacgg gcaaatgaga
     4021 atctttcatt tactgtgaaa actgatcgga ttgtttatga catgacacaa caagtcatta
     4081 ctattccagt caaaccaaac aaaagcgtga atgctagtga tgtacatgct gttctaacat
     4141 atggttggga tggtaatgga agttcagaaa aagttattgg ggaagtttat ttaaaagacg
     4201 tacaatggac cgctggtatt gagtatacaa taatgatttc tgcagaacta tcgattgatg
     4261 agatcaagag taaagataaa gttgatttga ttgtttttta tgatggacag atgacgatca
     4321 cggagaattt gaaaccaagc agttggacag ttgttggacc gccaagcagt acggatagca
     4381 caagtagtga aagcagtaca gaaaacacga gcggtgaaag cagtacagag agtacgagca
     4441 gtgaaattag cacagaaaac acgagcagcg aaagcagtac ggagagtacg agtagtgaaa
     4501 gtagcacagg aagcacgagc agcgaaagca gtacggagag tacgagtagt gaaagtagca
     4561 caggaagcat gagtagtgag agtagcacag gaagcacgag cagcgaaagc agcacaggaa
     4621 aagtaaataa tgaacttgat ttggtaccta tcataccaac taaggaacaa aagagaaatg
     4681 cagggagcaa cctaaaaagt gtgctaaaac agcctgattt tgtttctcgt ggaattgatc
     4741 atcaagaaaa agcgaaagaa acagataata gaaaaagcga tttaccagaa actggtagta
     4801 gaaccttgaa caagctaatt acatggatgg gtgtgttact cattttgatt gtaggagcaa
     4861 gctattttcg ttctctcttc catcgagtga aataaagaat aaaagcaaca gatctaaaat
     4921 tgaataaaac gatagatttt tgagtgaata tttcattcga gagtgctgta ttgcctggcg
     4981 aagttgtagc tttgccagat ctatttttgt ttactaacat atttgagaaa caggaaataa
     5041 caggaacaca aatggaaaat aagagcaaga ataattgaca atgcacactg cgcatggtag
     5101 tatctctgaa aaatcagtaa cgaatctatt tgtacgttat tcatgtagct gtcggaataa
     5161 gtctaaataa tagataaaaa ggagtatgta ctttgtttga agaatttatt gatatcaatg
     5221 aaaggcaagt atatcaattt ttgaactatt gttatgaaag agacgagaaa ttatatgtgg
     5281 tgaaggatat cgctttagat ctaaactaca ccctggctaa gatgaattcg gtgattcaac
     5341 aagcagaatc gttttgcgaa aggtatccag aatataaatt atcttttctt tcagaaaaca
     5401 agatgataaa agtcgagttt tcttctcagt ttttactgag taaagtttat tctatacttt
     5461 tagagggaac gattggttat attttactgg attcacttta caaaggtact tatcaatcct
     5521 tagaaaatct tagtcaaaaa attatataag tttgcgtacg attcaaagaa aattaagaga
     5581 acttaatact attttgaaaa actatcattt atcttgcagc ttgaaaaaag gtaatccgat
     5641 agaaggagaa gaataccgta tccgatactt ttttcacttg atgtattggc agtcattcga
     5701 cgaaaatcat tctgatatat tatcaagtat aaaaaataaa cgtcaactat tagaaaaatt
     5761 tgcgaaacat gcgccatata cgcgtagtat agatagaaag aaatggatca gcctactaag
     5821 aatttcgttg caacgaatga aacaaggcca ctcgattacg tatgtcccag aagagatgaa
     5881 caaatttgtg catccattga taacaaaaga agagtttacg cattacatac tagagccttt
     5941 ttttgaagca aacttctggt cgatgaatca catcactcca acagagcaag cttaccttta
     6001 ttttatgttt ggtgtaatga acacctattt ggaagaagat ttgttggata ctccagataa
     6061 agtacaagaa agttggggct ggattgaatc gtctattgta gaaaattttg aaaaaaactt
     6121 caagatttgt tttacaactt cagaaaaaaa ttatctatat gtcaatttgg caatgatcca
     6181 tttgtattca agggtttttg ggacaaaaaa gaaggtggat gcttttggaa aatcagcaga
     6241 agacagagat tttcagcata tatttccagt gatgtatcca atcatgcaac agttttttag
     6301 tggggtagct cgcagaattc cagagcttaa tacttattat gaaaagaaca gacggttgat
     6361 ttttcaatac tgtatgttag tcagggatat ttttataaaa cacgaacaac ctgtcatatt
     6421 ctatattcaa tcaaagtatg gtaaaacaca ggaattatgg gcaaagaaaa ggatattatc
     6481 tatgactgaa cgcccaataa aatatagtgc atccgctgat cagttacctg atattgtcat
     6541 tagcgattat cctatcgaca aaaaggcata tgatcaaacg aatacacaga tattttactg
     6601 gaatggacaa cctacaaaaa atgattgggc gcgtctgaaa gctgaaatca taaaaatcag
     6661 gaatgagaaa aatagatcca tattggaaaa attggatttc gttaattaag aaaagcagat
     6721 tgtttatgcc aaaattaaga cattgcaaaa agattatttt ctttaaaatc gacaagatga
     6781 ccagaaagca agagttcgtt gagctcttgc tttcttttag ttttagaaag gaacatcctg
     6841 attttatctt cgctaaatcc agtcaaaagt tttgcagatt ggtcgtagat aatcggtttt
     6901 ttcaataaag aaggggatgt acgaatctca atatatagtt cactcaaact gagttcatct
     6961 attctgtgaa caagattttt ataactaata gaatgagtag agagcatttc ggtcacgccg
     7021 ttgtttgtca attttagtaa gtggataaat tcatttttgg ttagtggttg acgaattaag
     7081 ttctgttcga taaacggtat atcatggacg ataagccaac gttttgcgcg tcttgaagac
     7141 gagcagccag aacctgtata caatttaatc atcatacatt cctccaatag ctaagtattt
     7201 atgaaataat aacatgaaga aatagtcgaa aagtgccatt tagaggtgta aaataagaaa
     7261 atgttgtcac gtataatgga actagctaga taagaaatac tattaaatca agaaaaaaga
     7321 aagaaggcac aagtatgtca aacacagccg acgcaatagt agtgatcgat ttacaaaaag
     7381 gggtatgttt tgattcttcg ccgatacacg aattagaaac agtgacagca ttagtgaata
     7441 aaagaatcaa aacatacgaa acgattggga aaccagttat tttcgttcaa cacgaagatg
     7501 ctcaattagt gccacaaaca aaaccatggg agctattgtc ggaattatct attcctgagc
     7561 acagttattt tgtgagaaaa acccatgcga attcatttta taagactaat ttgagtgttt
     7621 tattaactga attggactgt cattcgatcg aattatgtgg ggcacaagca gagtattgta
     7681 tagatacgac tgtgaagttt gctcatggat taggatacca gcttatgatg tgtagaggag
     7741 caacgacaac ttatgataat ccttttatga aagcaaagga aacaatcgct ttttacgaga
     7801 aaatttggga taaacgattt ctgacatttt tggagcaata agttgtttct tcgtttaaaa
     7861 aaagcagaat ggatactggt ttatccattc tgctttatta cgtaaaatga gaaaataatc
     7921 ctgttctatt tttatgggat aaaccattta ttttttgtat aaaaaatgtt tgcgtttaca
     7981 tataattctc ctagaaacat aaaaaggagt gaatagcttg agaacaaaac aagtattaaa
     8041 gggagcgttg gtcatcttat ttgctgtaag tacaagcgtc ccgcaatgga cagtatatgg
     8101 agagagcatt tcttccgaat cggaatctcg ggaggtagaa accacagaaa ctactgatgc
     8161 tggaaatgaa acgaaatcga gtacttcaca aacagaaaca aatactgaaa caacggttga
     8221 gacatctgtt actagcacag atcaagaaac gaccgctacc acagataacc aacaaacaga
     8281 agaagcaaca gctacaaaaa tgtcaaacga cgaatcctct tctgctaaag taagtgacaa
     8341 agagaatggg acagaaaatg atgatatcgg taaaggtgaa aatttcaatg gtaaagaata
     8401 tttgaattac ttcggtaaac agatgacaga aatacttaat ggaccaacag aagacatcaa
     8461 gtcaaaatta atagagttat tagtcactga gcttgctgtt aatgattatg gtgtagataa
     8521 agagattatc aaacatctga ttgctactta tctattgtac gatatcgctt ttgcaaaaaa
     8581 cagtgtgttg atgtcgatgc ttggaggtac agatgatggg acaacgccta cagaaaacac
     8641 aggcttctat ccaaatacaa aacaacttca tcaaactgta ctaaacaaac aagatggcaa
     8701 aatgatggat gtatatgcat attatgtcga tcaaggttca gataaaacag tcatgatcca
     8761 tggcggattt cgagggaatt ggaataacgg gatcgttaca gaagaataca atgattttta
     8821 taaggccggg tataatttat tatttgttga ttccagagcg actggtaata gcggaggcga
     8881 ttatgtgacc tatggacaat atgagtcaga tgacgtcctt tactggataa atcaagaagt
     8941 tcgagagcgg ccatctcaaa agattttact ttatggtggt tcgatgggag cagctacgat
     9001 gatgtctgta ttagcgaaag atattcctgt caatgtcaaa ggaattattg aaaattgcgg
     9061 atttgcatca attgatgaac aactacgttt tacgtacagc cagacagtag cccccgcact
     9121 accggatgcc ataaaaaatc agttagacat cattggggat caagagcatg aagatttatt
     9181 tatgggcctt ttgaaacaat actattttga tcaggagatg catttggata caaaagctgc
     9241 tctacctacg attggaatgt cagattcatt gcctaaattg attatccatg gaacagcaga
     9301 tgatgtagta cctgtgtcta acgcgcaaaa attatatgag ttatcaggag ggtataaaga
     9361 tcttttatta gtagaaggag cagggcatgg aaaggcacag gaagttgacc atgctgccta
     9421 cacgaaacat gtaacggact ttttgaaagt agtgttccat gatcagataa acgtaaagta
     9481 tgtggatgaa aacaataaaa gtctactcaa agaccaggac gaaatccagc tttacggagc
     9541 ttatggagaa aattatatga cagagcaaaa gacattcgaa ggatacgaat tagcaaatgt
     9601 tgaaggaccg actgaaggga tttttaatga gacgatacca actattattt tctattacaa
     9661 aaaaatccca gtagctccac caaaaaagca agatccgaca gagaatgcag acaataaggg
     9721 aaagaatgaa cctcgagagg atcaatcaag tgatgatacg caaccgattc agatgacagt
     9781 gaaagtacaa aaaaagacag atgcaaaaaa aagaatgttg ccgaaaactg gagaaaagaa
     9841 acattcgctt ctcatttatt caggtggatt tttatctgtt agcacgatta tcacatggat
     9901 ttggcgaaga aagagagggt aaatgaatga aatggttcaa gcgaatagtg attgcagtac
     9961 cagttatcat cgtagttatt ttagtcactg tatttttgat taatcaaatc acaccaaagc
    10021 cgattagctt gcttgttaga aaacaatttg acacaagtga aaaagaacaa gtatatgccc
    10081 gaccagatga tttccagcaa aaaatcgaac aaatcgatat aaaaaaagaa atatcctatc
    10141 cttcaaagta caaaaataat aatatggata tctacacacc gaaagtggaa aagaaaaaat
    10201 taccgattct tttctggatg catggaggcg catatgtagg aggggataaa aatgattgtc
    10261 gtgattattt ggaatatcta tgttcagaca cgcagcaaat catcgtaaat atagattatg
    10321 aacgatcacc ggaagcaaaa catcctacac cagttatcca attgaacgaa gccattcaag
    10381 cagctaaaaa agagataaaa gatcaagcag attggtcgaa tatttcgatt ggtggaaatt
    10441 cggcaggtgc acaaattagt ggagaatatt tgttagcact tcaaaatgaa gaaattaaaa
    10501 aagctgatca tcttgatccg actttggaga acaagcagat tacgaagttt atttctttgt
    10561 ctggtctgtt ggatccttct gcacttactc aagtaagtga taaaatctct agctttcttt
    10621 atgaaaaatg tggatgggct tactttgata ataaggactt tgaacaatca gagaaggtca
    10681 aaagtttagc cttggtcaga catgcggatc gttggacgca aaacacattc ttaacggatg
    10741 gaaatacaaa tacgtttacg aaacaaatgg aagaagtaac ttctgtattt gagaaagcgg
    10801 gggtgaaagt cacaaaagta gattatgcgg agaaaaatgc tgttttgaac catgaatatc
    10861 agtttgattt cagcaataaa caagcgcaag aaacatatca aaagttagta atgtttttca
    10921 aggagtaaag tcttatgatg caaaagaggt tgtaatctgt cacttagctc caagtcacaa
    10981 ggagcaattt caataaacaa gcttttcatg gtttatgaat attgtaactt gtgactgagg
    11041 agttagagat ggcaaggggc accttttatt cgaaatttgg gaatatcaca cgattattgt
    11101 cacgatctct tttacgtaaa ttttataagt cagatttgtt gttttgatcg tttaaaaaaa
    11161 gcaacaaatc cgaagcctgc ggaggcaaga agggacaaaa agccgagtgg taagcaaaag
    11221 aatgctggtt ccactaatat tccgttgtta ttgatataag gctgggaaca aagatgaata
    11281 gcaaataaaa tcaatgcact agcgaaaaaa agcaaagaaa tatggatagc tttcataagc
    11341 agcacctcct tttttataat tgtatgataa atagattaag aatctataaa tgtgacaagt
    11401 ttgttaggat gtgaataaaa tgatcatcta gcgaacttga aacaaagatg gctaatgata
    11461 agcaattaat gattcagcaa tcagataggt acaaagttta ccatcatacg tctagaccaa
    11521 taatagaaaa tatgggaata taatagaaaa gatttaggat acccccaaaa gaatttcccc
    11581 aaaaattcga tgtatcctaa acttttttat tttacataac aatcatatca actgtgaaat
    11641 aaaattacaa atgataacct aaaatgaggc caaaagccag tgttatcaag gaaatactta
    11701 attcaccaaa atttttttta attttttaga aaataagaaa caaaaataat aaaaaaaaga
    11761 aaagataaat tttttactac tgtatactaa ctttgttatc gcatctaaca agtaactcga
    11821 ataataccaa tacaaccttc tccaaagatg cgatgacata cgttctaacc caccgactat
    11881 tgatgttctg taccaccctt gcagaaccaa aaaagccact accaaatatt tggtagtggc
    11941 tttttttgtt ttatggattt ttcgcttttt ctgttatggt gctattcttt gatttcagaa
    12001 atagtatgtc gaactttagc gatagaacga cgtgattctt tttcgttgta aaacatcaaa
    12061 atcacatata gagagtccaa aatgcttagt tgagaaatac gggaagctaa agcttcagat
    12121 cggaattctg tttcttcaga aatagaaata aaaacgacat cgccaagttt agcaagggaa
    12181 gaattagctt ggctagtaat aacgattgtt tttgctccag tttttcttac ggtttcagca
    12241 atatggattg tttcttttga ttgccctgtg tgagaaatca aaacagcaca gtctttttcc
    12301 gtcaataaag aagcttccat caattgaata tggtaatccg tgctgtgaga agttgcgata
    12361 ggggaacgca aaaatttatg ataagcgtca gttgctacaa tctctgaacc gccaacaccg
    12421 aaaaaataga cacgtttaga ttcattgata atagtagccg ctttttttag atccttttgt
    12481 tgtaacaact tttttgtgtc atttaaagtt gaaatactag actcgaacac cttttgcgcc
    12541 atagtgagct cagtatctgt tttctgaata ttttcgtgga tagaaatagc agatagatca
    12601 ttttcttgga tcaacatggc cattttaaaa tctttaaatc cattataacc aagttttttt
    12661 gtaaattgaa aaaaagtaga gtcagcaatg cccagttcac ttgctaaatt gctaatagga
    12721 ctatgactta ctttgcttgg attttctaaa atataatcgg cgatagcctg ttcttttggg
    12781 ctgaagtcgt tgtacattgt tttgatttgt agtcttatgg agacgctcat gagaattcct
    12841 cattttcata ataagattat cattttttcc gttctcatta atgttaaaga tacaaggaga
    12901 gtaggaaaaa atcaaacaaa aaatattttt gtaaaatcta tttacaaaaa aatttttttg
    12961 tataatgagg gtataagaaa tggaggcgct atcatggaaa ttggtgtaat tggtttggga
    13021 aaaatgggat tgaatttagc tttaaactta aaagagcacc atcacaaagt acaaggactc
    13081 gacatttcaa gtacagctgt tagtcaggca agagaaaatg acattcctgc ttatcaagag
    13141 atctctgaat ttctagctac ttttgagcag aaaaaaatca tctggttaat gcttcctgct
    13201 ggagagataa ccgaaaacat gttaagaaaa ctttttccaa aactcggacc aggagacatt
    13261 attattgaag gcggaaactc ttattataaa gattcaatcc gtcgagcaga agagtttcag
    13321 aaaaatgaaa tcggttactt ggattgtggg acttctggag gaatcgaagg agcacgacat
    13381 caagcctgct taatgattgg aggagataaa gaaacttttc tatccgtgga acaattattc
    13441 aaagatgtag caattgaaag aggatatctg tatgctggtg catccggaag cggacacttc
    13501 ttgaaaatga tccataatgg aatcgaatat ggaatgatgc aagcaatcgg tgaaggattc
    13561 caacttgtac aaaaaagtga gtatgctttt gacttggaac aagtcgcacg tgtttggaat
    13621 catggttcgg tgattcgcgg ctggctgatg gaaatcatgg aagatcagtt aaacgaacat
    13681 cccaatttaa gtaattatcg gggaatcgtt tctgcatcag gtgaagcaaa atggacggtt
    13741 gaaacagcgc tagaaatggc tgttccagtt ccagtaattg caactagttt gttcatgagg
    13801 aatctttcac aggaagaaga tagtttttca gcaaaagtag tttcagcact aagaaatggg
    13861 tttggcggac atgaaatagt tgaaaagggt gagtaaaatg ccagattatc atatagcaat
    13921 cgttaattcc agcagtttcg gaagagtctt tccacaccac ttggaaagat taaagtcagt
    13981 tggagacgtt catttcttta ctgttgatca agagattcca ggaaaagaac tagcggagtt
    14041 acttaaagga ttcaatatca ttattgcaag tgttacgcca ttttttcgac gagatttttt
    14101 tgaaaacaaa gatgaactgc tattgatttc ccgacatggt attggttaca acaatattga
    14161 tttaaaagca gcaaaagaac accagacaat cgtatctatc atacctgctt taattgaacg
    14221 aaatgctgta gcagaaaata atataactaa tttgttgtcc atgcttcgac gcacgacaca
    14281 agcacaagca agagtcaagg acgatcgatg ggaagatcgg gcggagttcg tcggtaggac
    14341 gctgtttaac aaaacagttg gtgtgattgg tgcaggaaat accggaagcg gagtaatcga
    14401 aattttgcgt aacggttttc gctgtgatgt tctagcttat gatccttaca aatcagattt
    14461 atacatcgaa agctttggtg caaaaaaagt agaacttcaa gaattactgg aacaatcaga
    14521 tatcatttgt ttatgtgcga atttgacaga agagaactat cacatgattt ctgataaaga
    14581 agtcgatcag atgaaagaaa atgtttatct atctaatagt gcaagaggcg ctctagttga
    14641 tgaagaagcg atgattaatg gtctgaaaag cggaaagatc gcaggatatg ccacagatgt
    14701 tttagaagaa gaaccgggac gtcaagatca tccgtattta gcgtttgaac aagtagtgat
    14761 tacgccacat atatcggcct acacaaggga atgtttagaa gcaatgggtg aaaaatgtgt
    14821 cagagatgtc gaacagatca gtcagcacct tcttcctgaa cgttctgtcc agacaaagag
    14881 caactatata aaaggatgat gaagaaaatg gtgaacggtt taaaagtgaa aacaggccct
    14941 caattttatt tatatgaaga aggtggtatt tcaaaagttt ctgatctctt gaaatcatac
    15001 ggcgcgaaaa gagtactggt cacccacgga acggtatcat gggaaaaggc gctacctaaa
    15061 ttagtatttt tgaatgacga aacgattcaa tttttttatc atcgttattc tggagaatgt
    15121 agttatgctg aagccagacg aatagctaca atcatcaaaa aaatgaaatc gatttcgtag
    15181 ttggcgttgg cggaggaaaa ctgaccgatc tagtgggtta tagtgccaat cttgcaagaa
    15241 tcgatttcgg agtcatccct actttagcta gtaattgtgc tccatggaca cctcttgctg
    15301 tcatgtataa ggagaatgga caagcagaag ggaaaacaga acacttttac agacaagctg
    15361 ctttttttat aacagatccc caattagtga ttgattcccc tgttccatat ttcattgccg
    15421 ggttagcaga tacactagca aaatggtatg aatctgagct catcttagaa caagattttt
    15481 tgcaagatga atcatttttg aagctagcac aagatactgc gaagatctgc aaagaagaga
    15541 ttttgaatca ttctgctaaa gcaatccaag atatggcaca aagaaaactg acatcggagt
    15601 tcaaacagct ttcagagatt atctttgctg ttgctggttt agttggagga ttaggagata
    15661 aatacgcaag aaatgcggca gcacatgcta tgcatgacgc tatcagtaaa tatattccgg
    15721 aaagccatcg ttttctacat ggagaaaaag tagcgtatgg gattttctat caactggcac
    15781 tagaaggtcg ctgggaaaaa atagacgagt tatatccttt gtatcgggaa ttagaactgc
    15841 cggtttctct agaacaaatg ggattatttc cgaaagataa acagataata gataaaatgg
    15901 ctgaatttat tgattcgaaa gagaaagtgc atttgattcc tatagaggta acacagaaat
    15961 cactgataca gtcaatgatg gaactggaag gttatatcag aaagatctga aggaggagga
    16021 cacatggaaa cattaagtgt agtacaaagt ttgttgattg ctttatgggt agccgcggtt
    16081 atgtcccgct ggttaggtgg aggagccacg ttgaccttac gtttttctcc tttgatgact
    16141 ggattagtcg tcgggttgat catgggggaa gttgcacaag cgatgattgt tacagccgct
    16201 ttgcaaatga tttatatggg ggttttttct ccaggaggat caatgccagc tgaaccatct
    16261 attgcagcag ctatcgcagt accagtcgca ttattagggg atctgtcgcc agaagcagcg
    16321 attgccgttg cggtgccagt cggattgctc ggaagttact tgtatcagtt tcgttttttc
    16381 atcaatactt ttttaggtaa atatacagac aaagctgtag aagatttgaa tacaaaagct
    16441 atggcccgat caattattct ttatccaacg gttgcctcat ttttattatt cgttccgctt
    16501 gttttcattg ctttatattt aggggcgcca ttgatcgctg atgtaatcaa agctttagag
    16561 ggaacagtcg ttatccacat tcttgaagta gtaggtggag ggttagcggc aatcggtatc
    16621 gcgacaactg tatacgttat cggtcgaaaa gattatctgg tctttttctt ccttgcttat
    16681 tttatgagtg ttgttttgaa atctttagat attacgatgg ttacttatgc catttttggg
    16741 attattatcg ctttgatctt tgtccagtcg caaaaaggga aacaagtaca gcctgccaca
    16801 agcaataaca attcagcatc ttttgatgac gaagatgact atgatgacgg attttaattt
    16861 aggaggaatg ggaaatggct gaaataatgg ataatcaaac aggtgctcct gaagaaatca
    16921 cgaaaaaaga tgtaacaaaa gcctatctga gatggcattt tgcaaacgaa attcctcact
    16981 cttttgaacg ttacttggcg ccatcactac tatacggaat gatgccaatc ttgaaaaaac
    17041 tttataaaga tgaagactct ttaaaagcag catataaacg gcagttactg ttcttcaaca
    17101 ctcaattaag ctggggtggc ggtgtgatta ctggcctaat gtcttctatg gaacagcaaa
    17161 gagcagaaga agagtatgaa gaaaaagaga tcttgatgca ggatgacttg atgtataaca
    17221 cgaaagcggg attgatgggg gcactagcag gaatcggaga tgcaatcgat tcaggaaccg
    17281 tccaatatat ttttatcgca atcgcggtac cttgggcaca acagggaagt cctttaggcg
    17341 cactttttcc ttttatctgc tttgggttgt atcaggtttt actaggggta tttttcgcaa
    17401 gacaagcttt cactatgggc cgtaatgcta caggcctaat gcaaaacact ggtgttcaga
    17461 cagcgattga aatgctatca gttttagggt tgtttatgat gggggtgctt gcgggaaact
    17521 atgtaaaagt agaatcttca ttgaaatttg cgatatccgg acgtgagttt gttatccagg
    17581 aaattcttga tcaaatcgtg ccagggatat tacctttagc tgtcgtaatg ggtgtgtact
    17641 tgttctatac gaaaaaagga ttgaaagtca cacaagcatt attatggctg actggaatat
    17701 taattgtgct agcaggaatc ggtattttat aaaaagaagg gaacgtgaat aagatgggtg
    17761 tagtcaattt agcgcgtgtg gatgagcgtt tgatccatgg gcaagtaatg gtaacgttat
    17821 ctcaaaaaag tggagtgaat tccatttttg ttgtagacga agttgtagca aaagataaat
    17881 ttatgagaga tctttacaaa aatgcaggaa gccgtacagg acaaaaaaca attgtcatta
    17941 caccagagaa agctaaattc tattgggatg aatatcaatt taaagaatac aattgtattt
    18001 tgatcgcaaa aacagtccaa acgatttacg acttagtaaa acacggaatc cccatggaag
    18061 aattgaatat tggagggatt gctcaaaaaa atcctgatac agatctttta gtgacgaaat
    18121 ctgtttattt aaataaatca gatgctgaaa aattgaaaga aatgaatgaa caatatggcg
    18181 taaagaatat ttattttcaa gccactccat ctgcacctaa aacaggatta aaagatgtat
    18241 tgaacaagtt tgatttgtca taaacaaatg cttagaaaaa agataaagag ggcgaaaaaa
    18301 tgaagaagaa cgagctgttt cgtgattggg aatttcgtta tcgctatatt taccgtaagc
    18361 gccgtacaaa aaagagtaaa cagcgttttc tttcagcatt agtatcagat atttacagta
    18421 tgagaacaga tgtgacagtc attgcttacg atacgctagc ctaccgatca aaaaatattt
    18481 atgttggaga tatcgaaaaa gcagagaaag ttatctgtac ttattacgat acacccgttc
    18541 atgcattagg aagttatttc atgtttgatt ggaaagacca aaggaaaaaa acaatctact
    18601 ctatattatt gtccttcatt ttgttgttca gtttaggttg gtggggaatg atgatatata
    18661 acaaaaatcc tcatcacgta ttcgatctgc tatccgtata aacaggtatc actgtactag
    18721 catttgggag ctactttttc ttattgggaa aagcagctcg cggatggcct agcagacaaa
    18781 cttttattcg aaatacttca tccatattaa cgatgctaga aatgatccgt acgattgatg
    18841 atccgagtgt agcgtatgcg tttgttgatg aaggctgtta tggagaaaag ggcttagaca
    18901 gcgtgagatc gggtatgaaa aaagaggcta ttctttttta tctagactct gttggggcag
    18961 atacaccgct acagttttcg ggaaattatt tttcaaataa agaacagtgg ctgaaacaag
    19021 ttgataagtt gaaagaaaaa aacgtcaatt atatttttag tgcaagaaaa aagcaagcgc
    19081 agttcttcta tttgaccaaa acagatttac gagggaaaac atttaattgg caaaatgcca
    19141 atcagattat tgctcttttt cgataagtaa aaagtgcaaa acaaggagtg agaagactaa
    19201 tgttggaaat catgatcgtt acacatggta agttgagcga aggactgaaa gatgcggcgg
    19261 aagtaattgt cgggacatcg agccatattg aaacaatgtg cttagagtct ggggaggaca
    19321 tccaaacatt cggagagaag gtcaaagaaa aattaactat gatcaacaca gcagaaccca
    19381 tgctagtatt tgttgatcta attagcgcaa gtccgtacaa tcaagcgctc ttggcagtca
    19441 atgaactgac tgaagaaaag aaagcagcca cttatgtcat agggggcgtg aatctgccaa
    19501 tgttgttaga agcaatcaat catcagatgc ttcacacacc gatagaagaa gcggtggaac
    19561 aaattgtcaa acaaggaaaa gataatttaa ctgtttggca tgcttcagcg gaagaaaaaa
    19621 aattagatga ggacgatttt tagaaggaag gctgaaaaga tgaagtgggg atttagatgg
    19681 tatggtgaaa aaggggattc gatcccatta aaatatgttc gccaaatacc gggaataaat
    19741 gggataattg gaactttgct gactaaaatg cctggagatg tttgggagat ttcagaaatt
    19801 gaggagttga aagcatctgt tgagagccaa ggactggaac tgcttggaat tgaaagtgta
    19861 gcgatccacg atgcaatcaa ggcagggaca gatgaacgag attactatat tgataactat
    19921 atacgaacaa tcaaaaactt gtctcgatgt ggggttcgat tgatttgtta tagcttcaaa
    19981 ccaatttttg gatgggcgaa aactgatttg tttaatgaaa acaacgatgg aagctattct
    20041 cttttatacg atcagaaaat cgtcgatcag atggagccag gagaaatgta tcaattgata
    20101 cacagccagt caaagggatt caaattgccg ggttgggaag aagaacggtt gaaaaaattc
    20161 gctcagctgg aaaaactgta tgaaggaatg accgaagaag aattatttga aaatctgact
    20221 tattttttag aaaaagtgat tccagtgtgc gaaaaagcag atgtaaaaat ggctatccat
    20281 ccagatgatc cgccatggga actttttggt tttcctagag tgacgaaaaa tcttggcgac
    20341 ttgaagaaaa ttctaaatgc agtagattct ccatataatg gactaacgct gtgcacagga
    20401 tctttagggg caaatccgga aaacgattta gttgaaatca tccatgaggt aggttcgcgc
    20461 atccattttg tccacttcag aaacgtggag tttttaggag aaagaaagtt caaagaaacg
    20521 gcacatccct ctacagaagg ctcccttgat atgtatcata ttatgaaagc gttggtgcaa
    20581 gaagggttcg acggtcctat acgccctgat catggtagaa ccgtgtgggg tgaagtggct
    20641 atgcctggat atggcctgta tgatcgtgca atgggactca cttacatgca aggtctatat
    20701 gaggcgataa gtaaggaaaa accactggga gagcattatg aataaaatca agctcttcat
    20761 ctttgatatg gatggccttt tattagaaac tggacgttta gcttatcgtg cttatgtaaa
    20821 atcagcacaa aagtatgatt atgaaatgcg taaggaagtc tattatttac taactggcca
    20881 aacagaaatg gcgataagag aacaaatggg cattttgtac ggagaagatg ttccatatat
    20941 caaatggcga gaagcaatca atcaatataa agaaaaaatc gtgaaagaag ataagagagt
    21001 atatacgaaa aaaggagcag aagaaatttt atcttttgca aaagaaagag gaatccatac
    21061 aatcgtggct tcgtctaata cacgggtaaa agtagaaatg tatttaaaaa tggaaaatct
    21121 atatgccttg tttgatcaaa tcatttcagg ggatgatgta aaaaaaggaa agccggaacc
    21181 agagatcttt ttgaaagctt gttcaaaaat gaatattcct ccaagtgaag cacttgtatt
    21241 tgaagactcg attgcaggga tcgaagcagc aaggcgagcg ggcattttgt cttttctcat
    21301 caaagatcat ttgatagggt tgcccgatca taatgggaag cataagttga aagtagatgt
    21361 aagtttatat gaatccaata aagcagacta tgaattttat gacctgcatc aagcaaaacg
    21421 atttttagaa agtaaagggt tgtatctcta ataaagagga ctattttcta gtcctcttta
    21481 tttattgtcc tgcacgactg agggaacaga tgaaaaagaa gtaatttttt attttgaagt
    21541 atctacctta tttgtagtga acaatttaga acaaacacaa aacgcatcta ctgttatcta
    21601 ccagtagatg cgtttaaaga gaagaacgag aatcgtccat atgagggttt ccactcctta
    21661 tgcagatttt tttaattctt gcactgcttg ttcgatcgta acacctgtcg ctacatgatt
    21721 ggtattttct ttgtcaaaaa cgacaaatag attcaaatct gtatccaagg ttactcgata
    21781 ttgtatatct ttgttataga atgtcatagc cattctcctt tctttaaata cttgctgaaa
    21841 ggcaacgaac gcgttgataa cgaaattcca tttataagta taccaccaat tgaaaggttt
    21901 tcatagttaa gaaattttaa agtcaaaagt tgcagataaa agcaaataaa caagaaaaca
    21961 aaaagtgaat caatcgcggt tattcaactt tttcttcgat tcgaagacaa tagaagacaa
    22021 tgaattttat atttcattgc attatccttg tgttattaga aaaagcatga tatattaaat
    22081 gagtaatcta ttttgaaacg taatttgagc gatatatcta catagataaa actccttttg
    22141 cctatcaaat atttattgca acgaaaaaac gtacattgat acgtatcagg aggaatttat
    22201 ttatgaataa cggtacagta aaatggttca acgcagacaa aggttttggc tttatcactg
    22261 gtgaagatgg aaatgatgta tttgcacatt tttcagctat ccaaggtgac ggcttcaaaa
    22321 ctttagaaga aggccaagca gtgtcttacg atgttgaaga tggtcaacgt ggccctcaag
    22381 caacaaacat tgttaaagct taataaaaat tgacttttaa ccgtcttttc gaaagaaaag
    22441 acggtttttt tgtacgaaaa aatt
//
LOCUS       DAFLVO010000048        22164 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.048, whole genome shotgun sequence.
ACCESSION   DAFLVO010000048 DAFLVO010000000
VERSION     DAFLVO010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22164
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.048"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            230..2065
                     /gene="tdc"
                     /locus_tag="L1U99_001883"
     CDS             230..2065
                     /gene="tdc"
                     /locus_tag="L1U99_001883"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBN1212420.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            2370..3848
                     /locus_tag="L1U99_001884"
     CDS             2370..3848
                     /locus_tag="L1U99_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1212421.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            3814..5145
                     /locus_tag="L1U99_001885"
     CDS             3814..5145
                     /locus_tag="L1U99_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1212422.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            5259..7811
                     /locus_tag="L1U99_001886"
     CDS             5259..7811
                     /locus_tag="L1U99_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBN1212423.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(7818..9257)
                     /locus_tag="L1U99_001887"
     CDS             complement(7818..9257)
                     /locus_tag="L1U99_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1212424.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            9603..9965
                     /locus_tag="L1U99_001888"
     CDS             9603..9965
                     /locus_tag="L1U99_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HBN1212425.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            complement(10152..11009)
                     /locus_tag="L1U99_001889"
     CDS             complement(10152..11009)
                     /locus_tag="L1U99_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1212426.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            11129..12040
                     /locus_tag="L1U99_001890"
     CDS             11129..12040
                     /locus_tag="L1U99_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBN1212427.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            12047..13698
                     /gene="mdcA"
                     /locus_tag="L1U99_001891"
                     /pseudo
     CDS             12047..13698
                     /gene="mdcA"
                     /locus_tag="L1U99_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
     gene            13800..14099
                     /locus_tag="L1U99_001892"
     CDS             13800..14099
                     /locus_tag="L1U99_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HBN1212428.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            14089..15765
                     /gene="mdcD"
                     /locus_tag="L1U99_001893"
     CDS             14089..15765
                     /gene="mdcD"
                     /locus_tag="L1U99_001893"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HBN1212429.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            15769..16362
                     /locus_tag="L1U99_001894"
     CDS             15769..16362
                     /locus_tag="L1U99_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HBN1212430.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            16386..17462
                     /locus_tag="L1U99_001895"
     CDS             16386..17462
                     /locus_tag="L1U99_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBN1212431.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            17487..18356
                     /gene="mdcB"
                     /locus_tag="L1U99_001896"
     CDS             17487..18356
                     /gene="mdcB"
                     /locus_tag="L1U99_001896"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HBN1212432.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            18467..19231
                     /locus_tag="L1U99_001897"
     CDS             18467..19231
                     /locus_tag="L1U99_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HBN1212433.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            19720..21813
                     /locus_tag="L1U99_001898"
     CDS             19720..21813
                     /locus_tag="L1U99_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBN1212434.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            21838..22140
                     /locus_tag="L1U99_001899"
     CDS             21838..22140
                     /locus_tag="L1U99_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1212435.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
BASE COUNT         7178 a         3787 c         4722 g         6477 t
ORIGIN      
        1 ctttttttag gttatctatt ttagaagact gatttattga aaaattgttc gcttttttgc
       61 gttgaattat cagaaaaatc cgactttatt tatttttgtt tgtaaaaatc tacgtggatt
      121 tgatgttata aaaaaaaaat tctcattttt ggcgctatag tgaagaggtg ttacagataa
      181 acacatgtat ctgcaagaca ttgaccaaca aaatatggag ggaagaaaaa tgaaagatat
      241 ggatatcaag gccgtcttta taggcgacaa agctgaaaat ggaccagttt ataaaatgtt
      301 gttgaacaag atggtagatg aacatcttgg atggagagaa aattatattc cttcagatat
      361 gcctgcaatt agcgaaggag ataagctcac tccagattat ctagccaccc gcgaccatat
      421 gatagaggtc ttggatgaag tcagtcagcg attacgcgca ggatcgatcc catggcattc
      481 agcaggccgt tactggggac aaatgaatgc tgaaacattg atgcctgctt tattagctta
      541 caactatgcg atgctgtgga acccaaataa tgttgcattg gaatcttcta tggcaacttc
      601 gcaaatggaa gcagaagtag gacaggattt tgcttcatta ttcaatatga cagacggatg
      661 gggacacatt gcagcagatg gttctattgc taatcttgaa ggattatggt acgcccgttg
      721 catcaaatcg attcctttag ctgtcaagga agtgctgcct gaaaaagtga aaaaaatgtc
      781 tgagtgggaa cttttgaatt tatctgttga agaaattttg gaaatgaccg aaagctttac
      841 ggacgaagaa atggatgagg tcaaagcagc ttcttcccgt agcggaaaaa atatccaaag
      901 attagggaaa tggctggtcc ctcaaacaaa acactattct tggatgaagg cgttagatat
      961 ttgcggagtc ggcttagatc agatggttgc tatcccagtt caagaggatt atcgaatgga
     1021 tattaatgct ttggaaaaaa caattcgtga attagctgga caaaaaatcc caattctagg
     1081 tgtggttgct gtcgtaggaa cgacagaaga aggtcaagta gacagtgtag ataaaatcgt
     1141 ccaattaaga gaaaggttaa aagatgaagg gatctatttc tatttacatg ttgatgccgc
     1201 atatggcggc tatgcgcgtt cactgtttct aaacgaagca ggagaatttg tgccgtatgc
     1261 ttccttagct gaattctttg aagaacatca tgttttccac cactgcgtaa cgattgacaa
     1321 agaggtatat gaagggttca gagctatttc agaagcggat tctgtcacga tagatcctca
     1381 taagatgggc tatgtccctt atgctgctgg aggaatcgta atcaaacata aaaatatgag
     1441 aaatatcatt tcttatttcg cgccatatgt gtttgaaaaa tcagtaaagg ctccagatat
     1501 gttaggagct tatattttgg aaggatcaaa agctggagca accgccgccg cagtctggac
     1561 agcacatcgt gtattgccat tgaatgtgac cggatatggt caattgattg gggcttcaat
     1621 cgaggcagct caaagattca gagaatttct cgatcatctg acttttactg ttaaaggaaa
     1681 aacaatcgaa gtctatccat tgaatcatcc tgattttaat atggtcaatt gggtattcaa
     1741 agaacaaggc tgtacagatt tgaacgctat caatgaatta aatgaaaaaa tgttcgatcg
     1801 gtcttcttat atggatggcg atgtttatgg tgaacggttt attacttctc atactacatt
     1861 tacacaagaa gattacggtg attctccgat tcgttttgtt gaaagaatgg gtctaacgaa
     1921 agaagaatgg aaaaaagaac agaaaatcac tctgctacgt gcggctatca tgactcctta
     1981 tttgaatgat gatcgaattt tcaattttta tacaaaaaaa atcgccaaag caatggaaaa
     2041 gaaactaaac gaaatcatcc aatagaactg atttttgtgt gaaagaataa caagagacat
     2101 atggagaaca gacaattatt tgcttcatca aaacaattgt atttccccct gtttttcata
     2161 tattcctcgc caagatattc ttttttataa aacgttctat aagttggatc gttcgtttca
     2221 tgtatcaaac ccagttcact aagatcgttc aatggatgtt tcggtgatac tgggttttgt
     2281 actgaatcga tgaaaccttg tcatttctgt tcttgaacaa aaataaaaga aaacaaaaac
     2341 atatgtcgct attgaaagaa ggaataaaga tgaaagatac tggttcatca aagcaaatca
     2401 cgaccatgac ctttatcgga atgacctgcg cccttgtagc aagtgtacga aatattccag
     2461 atgtagcagc aacgagctgg acgatgattt tttacatgct ggttgcagta ttattgtacg
     2521 cttttccaat ctcattgatc tctggtgaat ttgctggaat gtttccccaa aaaggtggtc
     2581 cagaactttg ggtatcgaat gctctaggaa aaaaatgggg gttcgttgtc tcatggctgt
     2641 tatgggtcca aatgtttcct gggatggtga tggtcgcttc agcactcgct ccgttgtttg
     2701 gtaatattat cgataatgtg ccgcttggtt tgaacagcaa atttacatta gttgtcattt
     2761 tagtcgttta ttggatcatc acttttttga atttgaaatt tgatatggca aaaatcggcg
     2821 gaaaagtcgg tgtttggtta ggattgtacg tgcctttgac gatgatgctc ttattagggt
     2881 ttgctgcgtg gatcaaagtt gggatcgtac caaccggaac attaggcagt ttttcatggg
     2941 acaaattaat accagatact acgactgcat cctcatttgt ttattttgcg ccgatcatgt
     3001 ttatttttac tggtatcgaa atgtcctctg tgtatatcac tcgattggaa aatccagtta
     3061 aaacgtatat tcgcggagta tttgccgcgt taatttttat atttttcgtc aatattttga
     3121 atgctttagt tgtagcaaat gtcgtaccaa aaggacaaat ggaattgaat aatatcgcgc
     3181 aatctatttc gatttattgc caaattcttg gtttgccaca tcttattgtg aatctgttta
     3241 gtttacttgt cttcattggt gtagcagtcc aattatctgc ttgggcctca ggaccagcaa
     3301 agacagtgac agaaagtgct agaaaaggtg cgtatccacc aaaattcaat ttttggaaga
     3361 cgaatcaatt tgacgtatcc aaatccgtta ttttgactca gtctgtcatt atctcaatct
     3421 ttgcactttt ttatttgctg attcctggcg tcaatcaagc atttttgatg ctcgtaaatt
     3481 caactactgt tatctactgt atcgtctatg tcatcatggg gatcgcagtt ttgagattgc
     3541 gttatacaca tgcaaagttg aatcgaccat ttagaattgg aaaaaaagag aaaaagagca
     3601 atcttggagt ttggactgtc gttattgttt tatttgcggc aatcggattt tctgtcggac
     3661 tgacgatgaa agctggaaca tggatcaatc taattgcagt cacagccatc agtgtcattt
     3721 tgtttgtagt accactctgt attgaaaaaa taaagaaacc ttcttgggaa caggaagtcg
     3781 ccatgctgct tgaaaaagaa aaaggtgaac ttgatggaaa aaccggcaat gaaacggact
     3841 ctaactaatc gaaatatcca gttaatcgca ttaggtggcg caattggaac aggattattt
     3901 ttaggttcag caaaggcaat tgcatcagca gggccagctg ttattctcgt ttatttgata
     3961 tgcggtttgg ctatttatgg tttgatgcgg gccatgggtg atttattttt agcaaatagt
     4021 acatttaact ctatcagtga tttcgttgac tattatttag gcaaaaagtg ggcatttttt
     4081 gtcaattgga cttattggct ttgctggctt ggagctggac ttgcggaatt aacagcaata
     4141 ggattgtata tccatttctg gtttgtacat gtaccagctt tgataagcgg aggtagcgca
     4201 ctaatgatct taatggcagt caaccttgtt gcagtcaagt ggtttggtga attggaatct
     4261 tttttctcaa tcatcaagat cttggggatt ttccttttta tcttattggg tataggattg
     4321 agtgtctcag attttcatac ccagtctatc ggaatcaaag aaaattttgg acagatcgat
     4381 gaattactac cgtttggctt tgctggaatg gtagtctcat ttcctatggt tttattcagt
     4441 tttgctggaa ttgaaatgat cggcttaacc gttggcgaga caagtgatcc gcaaaagaat
     4501 ttgaaaaaag caatcaactg tctgccttgg cgtattctct ttttctatat aggaacgatt
     4561 ttgtcgattt tatttgttgt tccatggcat tgtttagatt taaaagaaag tcctttagtg
     4621 actatgctgc aagtgatcca ttgccaaggc ggagcagcaa ttgtcaatct aatgattttg
     4681 gttgcttctt tgtcctcagc aaatagtgca gtctacagta ctagcaggat tttatatcaa
     4741 acagcaaaag aaaaaagttt gccccattgg ttttgtgcgc tttctaagaa aggcgtacct
     4801 ttacacggta ttttaattac aggaatgtta ttttttgccg gtctttgtct acattttttt
     4861 gtagctgata gtcgattgtt ttttcagctt ttggcaggca tgacaacgag ttgttttcta
     4921 tttgtgtggt cttcgatctt gtgtgcacat gttcaattta ttaaagaaaa gaaacggaac
     4981 actacacaaa gatataaaga tcttgctttg ttggtgtttt ttacttcaat tgctttcagc
     5041 ttgttattcg aaagcacgac acgctttatt ccttttttat tggttatctg gtttgtattc
     5101 ttaaattttg tatataaaag aataagcaat agaaatatca gttaggccca gatacatttt
     5161 gcaaaacgaa ttatttcaga cccccctgaa ataatcgata cgcctgaaaa aacttccctg
     5221 cgtataataa cagtatcaat taaacaggag gggataggat gaactggtac agattgacgg
     5281 tagaagatgt attgaaaaac tatcaaacat caacagaagg cttgtcgcaa gaagaacgac
     5341 agaaacgcct gactgatcaa ggatataatg aaataaaagc aaggcagcag acaaaacgat
     5401 ggaaaaaaat agcaaagcat tttactgatc tgctgatgat cgtgttgatc attgcctctt
     5461 ttttgaaatt tgcttctagt gaatatattg aaggaagtat tattttattc gtagtgatcg
     5521 tcaatggact cgttagttac tggcaagaaa gaaaagcgga agaatcattg aatggtttga
     5581 agcagctgat gggacaagaa gcgatagtac tatcaaacgg gatgcaagaa aaaatccctg
     5641 cgaaagaact ggtaaaagga gatgtcattg tcttacgtgc cggagatgtc gttccagcag
     5701 atatccgatt aatcgaagca catgatttat tagtggaaga atcgattttg acgggagaat
     5761 cagaagcatc tgaaaaaagt catgccgttt tgacagaaga agaatcgatc ggcgaccaga
     5821 aaaatatggg tttttcagga acgcttgtac aatctggttc tgcagtcggt gtcgttgtag
     5881 aaacaggaaa cacgacagaa atcggtaaaa tcaatcaagc attgcaatcg gtcgaacaac
     5941 aaacgacgcc tctgattaaa aaaatcaacc gattaaacaa acaaattttt caaggcattc
     6001 tttgtttgag cctattctta gttattttta cgacatttcg atatggtatg gattggcata
     6061 tccttctttc ggctacgatt gctttggtgg tgtcaatggt acccgaagga ttgccagctg
     6121 ttttgaccat gattctatcc gttggagtac atgaaatggc aaaagaaaag gcgatcatca
     6181 aaggacttcc ttcggtagaa acattaggtt ctatgacagt gatctgttca gataagacag
     6241 gaacattgac aaaaaatgaa atgacagttg tggatgtagc tgcaaaagaa gaagcctgcg
     6301 tgttgtccat tatgaaaaac tgtcaggaat taaaaacaaa agaagaacag aaaacagaaa
     6361 atttaagtgg caatccgaca gaagttgcgc tgattcgaca cacagaaaca gccaatctac
     6421 ctttgaaaaa aatagaagca aagattccgt tcagttctga atacaaatat atggcaacga
     6481 tgcatgcgga ggaaaaagga gcggtgattt acgtcaaagg tgcaccagaa gtattatttg
     6541 ctaaatcaac tctttcttct gcagaacaag aagcatggag tcagacagct gcagaatttg
     6601 cgagaaaagg tcagcgtgtt ttaggatttg cttataaaaa agtagattcg aaacaggaac
     6661 tcacgcatga gactttaacc caattaactt ttgcagggat cgccggattg atcgatccgc
     6721 caaaagaaag tgcagtcaaa gctgtaaagg aatgccaaca agcagggatc tcagtgaaaa
     6781 tgattacagg ggatcacaaa gacacagcaa aagcgattgc ggaacaaatt ggcttaaaac
     6841 atactgccaa agttttagaa gggatcgatt tggatcttat gtctgatgaa gagttgattc
     6901 agcaagtgcc aatagtcgat gtctttgctc gaacgacacc agaacataaa ctgcgaattg
     6961 ttaaagcttt gcagaaaaat ggagaaatcg tcggaatgac cggagacggc gtaaatgatg
     7021 cacctgcttt gaaaagatcc gatgtaggaa ttgctatggg aatcaaaggt agtgaagtaa
     7081 gcaaacaggc agctgatatg gttttaggag atgataattt ccatacgatt gcaaaagccg
     7141 taaaagaggg ccggcggatt ttggataatt tgcaaaaaac catcaatttc ttcttgccaa
     7201 ctgcattagc tcaaggattg atcttgattt gggcacttat gctgaatcgc ccgctacctt
     7261 tgtccccagt acagatttta tgggtcaata tggtaacgac aatcacttta tcttatgcac
     7321 tagggttcga gtcgccagat ccagaaatca tgaagcgccc accaagagat ccaaagcaag
     7381 gaatcctatc tggttatcat ttgtttcgga tcatctatgt ctccctactg atcatggttc
     7441 ctgcctattt attggctatg cagtttgaag ggcaaagctt acagcaaacc attcttctgc
     7501 aaaatatcgt cttagctcaa gctgtttaca tgatcaattg cagagagttg tccaagccgt
     7561 cattgaacca aggtcttttg caaaacaaag cgctttttct ttcattaggt atccttgctt
     7621 tattgcaagg gatggttatt tttctaccag tcggccagca gctgatcggt acagtaagtt
     7681 taacgatgac acaacagtta ttgattggag caaatgtgat tcttctattc ttagttgtag
     7741 aaatagaaaa agggatcatg aacaaactgt ttcgcaaaaa agaaaaaaca gctagagaat
     7801 acagtcgcta gccgttacta taaaaaagtt ttgaaagtga gttcagtcaa acgattgagc
     7861 tcatttttcg ttggaataga agaaatgtat acaataggga tatctagaga atctagaggg
     7921 aaattggaaa tcaagatatc tgttttttca aaagaaatag tggaaagatc ggttagttcg
     7981 ataggtaaga agcagacacg ttttcctaag taatctttta attcctgctg caagaacgcc
     8041 ttccatgaag gttctccttg gaaaataaaa tagacattga acaaattcgg tttgatagaa
     8101 aaaatcgttt gttggatcag tagagacaag agttggagaa agtaatttgg ttcattgatt
     8161 tctatttctt tttttagatc gttcagtaaa ttctctttct gttgatacaa gtgtgcatat
     8221 tgctgatcat atgtttctaa aaaacgatgg tattgacggt ccaatgcttc aatcaatatc
     8281 ggcgattcat gatattttaa tatgaggaga gccaagttat cagtcagaga tgtttttttt
     8341 agttgatcaa gagacagctc tgaagctagt tcctctacaa acgtttcgag gacctctaaa
     8401 aatggagaat gatgcaggca gcgagcggtt tcttgtccat agttattgtt gtaattccaa
     8461 ctttccagaa agcagaaaga agcaaaagaa agctcagtgt ctttaagata aataccttcc
     8521 gttaaataca attttttcaa tgcagagtca tacagggagg agagtgtgct gttggtatgg
     8581 atagaagaat ctaatcggca attcgctttt atacggatcg tattgataaa gaaccaacat
     8641 gttccgaaaa tctcttctgt ttcaaccgct agttcagttt gactgaggtt tcttaaaaat
     8701 tgaaaataat gggattcatg gatcgaataa tcctcgaaaa aatagttgtt atgagtgaaa
     8761 ggaatcagca atcgatgata aaaagtacga atcgcacgct cttttccaag aatacaagct
     8821 gtatatttcg tcaaatcgat ctgcaagtcg taacttgcta aacgctgatt gattttagtc
     8881 acatgtcttt tcaatgtccc ataagaaagc ccatggtcgg ctagaaaatc agggacagca
     8941 actttttttg taaaaagcag atttttcagc agttcgacac tgactgattg tttgaaaaaa
     9001 atctcccaaa ggtcatttgt taataaattt tgctggtttt gcaaactgat tcctgcttga
     9061 tcgctgatga tgtcccagcc ttcgggcagc tgagagcgaa tagattgaag gtcagaaaaa
     9121 atcgttcgtt cggttgtccc tatgatttca gctaattcat ttacggttat ctttgtatga
     9181 ttcagcaatt gttctactaa agaaacatga cgtcgaatat ctttttcggt aatgattttt
     9241 ttcattagtg aatacatcaa tcagactccc ttctattcta agaatacgga gaaaataaac
     9301 ggtggtcaag tttcaactga tttttcaatc attgtttatt tttctggagc atttactgat
     9361 gataagaatt tcatcatgaa cttgaaaaat gataccacta aaatcaaaaa ataggtgggc
     9421 aaacaataat aaacatttta atagtagatg gtagcaagac caacacaggc ggattgaaca
     9481 tttaagagtt gataaaaaag aaaaatatcg aagtatttga ttagcaacta cttgtattca
     9541 tttttctatt cttacgtggt atctttgaat aaagcgaatc aataagaaag agatggaagc
     9601 agatgctaac gaaaaaagaa ctaatcgatc acatcaatga aacatacaat ttgtctccag
     9661 aatatatttt taaaaaattt cctgattatt gcgtattcag acatcaaaaa agcaaaaaat
     9721 ggtttggggt cctgatgtct gttccagaag aaaaaatcta tgatgatgca agtgaccata
     9781 ggatcatcaa tattcttgat ttgaaggtcg atcctgaact tggcggaatt ttgcgaggaa
     9841 aagaggggta ttttccagcc tatcacatga ataaagaaca ttggatctct attgatctac
     9901 gtaaaataga aaagctagat gaactagcag atttgattga tggaagtttt aaatcaacgc
     9961 aatgaatgtc taggacaata gagaagaggt tgtgacagaa atgtttagct tcaagaaata
    10021 agaaggaatt tacgaaaatt gcttctcaaa tttttgggaa atttcggctt attttctaag
    10081 aaattacttc tggaacaccg tttgttcgaa aaaagagctg cgacaagaat tttgtcccag
    10141 ctcttttttt tttattttcc taaataaaat tcccgcatcg tttttgcaat cattttgatc
    10201 aaaggatgat cttctgtgaa gctagaagat aaataaattg ttcgtgtcaa gggcaaatct
    10261 ttgatttccc gcaagacgaa aggatcattt ttatcgtaag accaagaaac ttttgggaaa
    10321 aagctaacag ctaatccttg cttgacaata gaacgtaatg tcgcaggatc atctgtcgtc
    10381 gaactgatcg tcaattcgat acttttcgct tcaagtgctg catccagtgt atgacggaag
    10441 gcgttgctct ttgacagcat caagatgggg gtgcgttgga tatcttctaa ttgcagatgt
    10501 tcttttttag caagaggatg tttcttagga atggcgacat aaacaggttc tttcatgata
    10561 ggaatattgg tcatgccagg cttcatctcc gaagtgatgt acagtacagg atcggtaata
    10621 tcatctggta aatgatgttg catgatcgtt aattggatat caggatgctt ttccataaaa
    10681 attcggacca agttcggaat agaaacagag gctacctcta aatacaatat gacggaagta
    10741 acgatcttct cattgaccga agacaataat ttgattcctt cttctaatgt gtctaatgtc
    10801 ttgactgcat atggataaaa ttcttctgca taaacggtcg tctcaatgtt tctgccgcta
    10861 tggtaaaaca aagggacacc taattcgttt tccaaatgtt tgatcgcacg gctcaaggca
    10921 ggttgagaaa taaataattc tttggctgct tgggtaacat tttttgtttc gaatactttt
    10981 ttaaaatact gcagatgaag caatttcata attatccatc ccatccatac ctttttgtta
    11041 tggttttttc tttttttggc attttttatt atagcagaaa ttgactaaga tagcagtgga
    11101 aaaagtaagt gctgaggagg cgaggctcat gagtacaggt ttcttatttc ctggacaagg
    11161 cagtcagaag ttagggatgt tagcggatat ccctgaaatg tacatggaac gtttagaaaa
    11221 tgtgacgggg tatcggttag ttgataaaga agaaaactat caagatacgg tttttatcca
    11281 gctagcatta ctgacaaaag cagtatttta tttagatgaa atggaaaaaa acggtattca
    11341 gcctgatatt gcagcaggac attcgattgg tgctttttgt gcagctgttg cttgtcgatc
    11401 tttgagattt gagaatgcag cggaactagt ctatcaccgc gcagtcttaa tgaaagaagc
    11461 ttatccaagc ggttatgcaa tgggcgtagt agtaggtgtg acgagaagcg aagctgagga
    11521 aattgtagca aaaacatttg atcctgacca tccagtttat ctgtcaaatg aaaattgtcc
    11581 gatgcaacat acgttatctg ggagtatcga aggtttatcc gttacgttgg cagaagccaa
    11641 acggcaccaa gcgcaaacag cgaagctgct gaaagtccct gtgccatctc actgtctctt
    11701 gatgaatgat acggtcaaga aattcaagcc gtatatgcag tctgtccatc tatctgatgc
    11761 tagatgtttg tatataaaaa atacggatgg aagagccact caggacgcag aagagattcg
    11821 taaagatttg ttggaaaacc tagctttccc tgtgcagtgg aaccaaatga tggacttggc
    11881 aaaagaatta ggaatggatc tgacgattga atttcccccc ggcaatactt tgacaaagct
    11941 gattcataca aaatttggtg tagataaagg gatccgtacg atcaatctag accaacatgg
    12001 tattgatgac gccacgtttc tatatcaaaa atggagatga ctaattatgg aaaaaccaaa
    12061 ccgcaactgg gcttctaaac gcgaaaaaaa agcgcagcga ttggaaaaaa tcagcaactt
    12121 gctcaatggc aagtatgtag aaactgaaaa aatcgtagaa gtaatggaaa aactgattgc
    12181 tcccggcgac aaagttgtat tagaaggcga caatcaaaaa caagcaagtt ttctttcaga
    12241 aagtcttgaa aaagtagatg cagaaaaagt gaatgatctg catttgatca tgtctagtat
    12301 ctcacgacca gaacatttga atatttttga aaaaggaatc gcaagcaaga tcgatttctc
    12361 ttatgctggt gcacaaagct tgcgtgtcgc ccaaatgatt gaagacggca caatgaaatt
    12421 aggtgatatc catacttatt tggaacttta tggacgctta ttcatcgatt tgattccaaa
    12481 tgttgtttta gtagctgcag ataaagcaga taaagacggc aacttgtaca caggtttcaa
    12541 tacggaagaa acaccaacaa tcatcgaagc tgcagctttc aaagatggta tcgtgatcgt
    12601 tcaagttaac gaagttgtcg attctttacc acgtgtagat atccctggtg actgggtaga
    12661 cgttgtcgtg aaagcagata aaccttatca attagaagct ttattcacac gagatcctca
    12721 aaacatcaca gaattgcaaa ttctaatggc aatgatggca atcaaaggaa tctacgcaga
    12781 acacggcgta caatctttga atcacggtat tggattcaat acagcagcta tcgaattgtt
    12841 actgccaact tatggtgaat cactagggtt aaaagggaaa atcgcgaaga actgggtatt
    12901 gaacccacat ccaacgatga ttccagccat cgaatcaggt tgggttgaaa gcatccatag
    12961 ttttggtggc gaagttggta tggaaaaata tattgctgct cgcccagatg tcttttttgt
    13021 cggtaaagac ggcacgatgc gcagtaaccg aacattatca caagctgcag gacaatatgc
    13081 catcgatatg tttatcggtt caaccttgca attagattac gaaggaaact cttctaccgt
    13141 aacaaaagga cgtttatctg gttttggcgg tgcgcctaac atgggacata atcctggcgg
    13201 tcgtcgtcat tctacaccag catggcaatc acttcgcgac aatgatgatc cattagggaa
    13261 aggccaaaaa ttagttgttc aaatggttga aacatatggt tcaaataaaa aaccagtctt
    13321 tgtcgaagaa ttagatgcac tagctgttca aaaacaagca ggcttagcca atgcaatgca
    13381 ccagtgatga tttatagcga agatactaca catatcgtga cagaagaagg aattgcttat
    13441 ttgtacaaag caaaaacaaa agaagaacga caagcagcaa ttgcagcaat tggcggtgtt
    13501 acacctcttg gaatgactag cacgaaagaa tcactagata gcttgcgtgc agccggcatc
    13561 gtgaaattac cagaagatct aggcatcaaa cgtagtgaag cgaaacgttc attattagct
    13621 gcacaaacca tcgatgattt gatcgaatgg tcagatggcc tgtatgaacc accaatgaaa
    13681 ttcagaactt ggtcataaaa ttggcgagaa aaaccttttg tcgccattta cccagatgga
    13741 agaagaaaga cgaataagca gaacgtgtat gctctgtttt acaaaaaggg gagagatcca
    13801 tggaacaatt agcttataaa tatccaacga aacagccgat caataagaaa atccatgtag
    13861 gagtggtcgg ttcaggagat ttggaaatct tgatgtttcc aacagaaaaa acagaatcta
    13921 ctgtaaaaat ttgtacagga agcgatggct tcggcgaagt atggaacaat gtattaacga
    13981 gattttttga tcgttatcca atttcagcag atatcgtgat caatgacttc ggtgctacac
    14041 caggagttgt gtacctacga ttgacgcaag caatggagga actttcagat gaaaaatagt
    14101 tttgtagaat taaacgccag agaacgagtg aacgctctac ttgacaatgg acgtgaattg
    14161 attgatccat tcgatcaaat catcgcgcca agtttaccag cacaaggaat cgtccctgaa
    14221 agtgatgacg ggatcgttgt cagccgtggc acgatcaatg gcaaacaagc agtagtaatc
    14281 gctatggaag gaaaattcca aggtggcggt atcggtgaag tttccggtgc aaaaatcgtt
    14341 gctgcacttg aacatgtgtt agaagaaaat aaaaaaggaa atgagatctt tccagtcatt
    14401 gtactagata caggtggtgt tcgtttgcaa gaagcaaact acggactgtt atctatttca
    14461 gaaatcggaa atgtaatcat tgctctaaaa caatatgtac cagtcatcgg tttgattcca
    14521 ggacgtgtag gatcatttgg cggtatgtcg attacttcag cattaatgag ttatttaatc
    14581 gcaacaaaaa aagcgagagt cggtttgaat ggaccagaag ttattgaaca agaagcaggc
    14641 gttcgagaat ttgattctag tgacaaagac ttgatttgga atacattagg atctcgtcaa
    14701 cgggtagaat caaaaatcat tgatgaatta gtgactgata gtgtagaagc aatcaaagct
    14761 gctgtcatcg cagcaatgga cgaacgaaaa gacacgcatc gcagtgaaag ctcagcattt
    14821 tatttatcat tacttgattc tttagatctt tcaaaaccaa tggccattga cgattacaat
    14881 gaagcaattg ctaaccatca agcaaaatca attgacttac cagaagtagc agaaggaaat
    14941 gaaccagctg cagcaagtgt tggttacgat tggtttgcgg cactaactgg catgaaaaat
    15001 ccaacttctt ctattagtac tgtgtattat ggtaaatcaa gtaaattcat agaagaagcc
    15061 atcgtgacat caatcgtacc tgatcctaaa aacccgatgt accgtgtacg aaacggtgaa
    15121 gttggtttag ttgaaggttt ccgcatggga caaattttgg atcacgttta cgaagaagat
    15181 aaagacaaaa aagtgaaacg gccaatcatc gttgtgatcg atgtaccaag ccaagcatac
    15241 ggctataacg aagaattgat cggtatccat gtggctttgg ctaatagtgc tgctgcttat
    15301 gcaaaactcc gtcaagctgg acatccagtt attggattga ttgcaggaaa tgctatttca
    15361 ggtgcatttt tagcacatgg attacaatca agccgcttga ttgctttaaa caataaagaa
    15421 attaccgtcc aagcgatgtc taaagaaagt gctgcacgtg tgacaaaacg ttcggttgct
    15481 gaaatcgaag cagctgctga aaaagttcca gctatcgctt acgatatcaa taattataca
    15541 aaactaggag cgatctatca tttcctagaa gatatcaccg accaagctgc ttcagaacaa
    15601 aatgtcagca aagtcatcga agcaatcaat gaagccattc aagatgtccg caatacaaat
    15661 gacacgatgc tgacaaatcg atacacaaac gaaacagcca aaacattcgg acgtgtcgaa
    15721 acaaataaag tccgtgccaa aatggacgaa gaatgggatg cataaaaaat gattcaagca
    15781 catgatattg tcctttttga taaacatgaa atagaagggt tcaccttgcc tgaatgggtc
    15841 gttctaactg aaaagatgtt cggaacagtt cgtcgtgcgt cgacggatca cgcagaaata
    15901 ctaccgattg gtttacgtgg acctgcccgc aatcagagat ggtcaacaga aatctcaaaa
    15961 catgccgtca aacaagtcat tcatccgtgg gacatcatcg aacaagaatc gtatagacaa
    16021 gagaaaatca tggattatcc tgtttatcag caatttcatg ctgctagaaa catattatca
    16081 ggatgtaaat ggggaatcgg cggcagctta ggatttgaat tatcgactgg gattccggca
    16141 gtaaaagaaa ccagtgattt tgatttgctg ctgtacgcaa attcaccgat tgaattgcca
    16201 attcaggtaa ttcaatcgca tcctgctttt tttgagcaat tcgataccca agtagtgact
    16261 cggcaaggcg gtttttcact aaaagagtat ttgagagagc cagagaaaaa aattctattg
    16321 aaaacagtcg aaggacctaa attaaccaaa gaactttggt aataaagaaa aagagagaga
    16381 aagagatgtt tgaaaacaaa aaaatcaaaa tcaacgtaag tgacttccag aaagtatcag
    16441 ctgtaacggc tgttatgatg caaacgatat tgagctttgc tttggcaaac agccacagcg
    16501 caacaaatac agcttttctt ggtacctttt acgtcatcgt taaatacaca gcaccaatgt
    16561 ttatttttgc aattgtttat aatatggtaa aaacaagtca gcatttgtct tattgggaat
    16621 ttttgaaaga aaagtttttt gaactagtcg ttccgtatct tctatggacg acggcttatc
    16681 tttggctatt tccagcagtc caacaacaaa ctccgtatac ggatactgca agctttttac
    16741 tgaaatatgt cacaggtgat ggagcgcctc atttatggta taccgttatg atgctgcaga
    16801 tccaattgtt catgccgttt tttgtttggc tcggttacaa agtatttgct aataaaaaat
    16861 atgtatggcc agtattgatt ggttcaacga ttttatatgt cgcatggtat ctgttctatc
    16921 aaacacaagt attgactggg ccttatcatg acagctggta cttattagat cggtttgttg
    16981 ctagtttcat gatttatggg gtagccgcat ttgtttatca cgaaaaagtc tatcaatatt
    17041 tggacagagt acgttatctt ttcttacctg ttgccttagt tatcgcgttc ttttctgtcc
    17101 gttcattgct cgcacatcca ggagacttga gctttgcgaa tgcaccttac ttgaatacga
    17161 tccaaagttt atacagttta gtcatcatct ttgctgtctt cataggcgct tccaaaatga
    17221 ttgtaaacga ttcgccaaaa ttgccattgt tcaaatggtt gtctgtttat gcttatcgta
    17281 cgtatttagc caatgtattt gttttccaag tactgttatt attgtttaaa gatagttggc
    17341 tgcagttacc ttcaggagtc atgattcttg tagcttatct aatgacggca agttgtgcat
    17401 ttgctttaag ctggttactt catatcattt gggtagctat caaaaaaggt ttcagcaagt
    17461 aatagtagga agaaggagtg agtgtcatga taaatgacga acgaaaaaaa gcagtgactc
    17521 agcaactcgc tgcgttggta gaggaagcat tgatcgcaga agtaacatta agtccaaaac
    17581 ctggattagt ggatgcactg gatgcgggtg cacattccga tatggactat gctttatttc
    17641 ttaagtctgc taagacgcta actccttttt ttgaagaaat ggctcaaata gcatggcatc
    17701 atgctattga tcaggagtta agagaaagaa ttgctgagat tgggcgaaaa gcggaaaagg
    17761 caatgctgat tgctacaaat ggcatcaata cccataaagg agcgatttgg gcaatggggc
    17821 tattgatcag tgtcattgca caaaaaatca gtatggaaca gcctttttct ttatcgaaaa
    17881 tacttgatga tgtcagcaag cttgctgctt ttcctgatac aaaatatcgt cataaaaaaa
    17941 ccactcatgg tcatagggtg aagcaaaaat atggcgtaaa tggtgcatat gaagaagcga
    18001 tattagggta tccgcatatc aggcttgcaa ttcaagcagc taaggagcta gataatgatt
    18061 catatgtaca gaaacaaatg catatgttgt tagttttgat gagttcgcta gatgacacat
    18121 gcgtattgca tcgcagtgat cagaaaacgt tagtggaaat gcaaaaactt gctcatgctg
    18181 ctagtcaaag tgctttacca aatcgtccat ttacagcact gttgcacttt tgtcaggaaa
    18241 accaaatctc tcctggagga agcgcagatc tcttgtctgc aagcttgttc atgctgaaga
    18301 tagaggaatt atggactgcc gacacataca tttgtccgat gttactcaat gactaaataa
    18361 gacaaaattg ctaaaaaaac agtttatgca tctggttatt gactcttcct tttagcaagg
    18421 ctatcataaa aatagttttt tgtaataaaa gataacgagg aagacaatga aaaaaatcaa
    18481 ttatttagca atcattttgt tagtgggcct atgtttgttt gctctgccga cccaaggatt
    18541 cgctgtcgcg ggtggtcatg gtggaggtac atctagcggt cgaagttcgg gcagaggttc
    18601 atttggtggt cgttcatatg ggggcagtta ttttggcagt cgttcttacg gcagagattc
    18661 ttatgggtat tatggtccag gtacaggtcc ttctagttat gagcaaacgg gatttcttgc
    18721 attagctgtt ttgtcagtag gaggggtttc tgctttttct atcgtcaaga ataaaagaca
    18781 aaagaaaagg ctgaaagcgg agatattgtc ccgcatgtca ggaacggcta aagaaaagaa
    18841 agcacagttt ctggaaatcc aaaagatatt catgaagatc caatccgctt gggaagaaga
    18901 aactcctgaa aaagccagaa gctgttatac agacaagctg tttgccgaac atcagaaagt
    18961 tctgcaaaaa aacaaagcag acggtgtaag aaatcatact aaaaaaataa ctattcagga
    19021 agtaggaaat tatcgacaga tccacgaaaa tagttttgcc atccgaattg atttcagatg
    19081 ctgtgattat tcagtcgatc gaaaagatgg gcgattgatc tcaggaagta agacacaacg
    19141 acagtatttt tctcagatat ggtattttga tttttctgag aaagaaaaaa gatggcaagc
    19201 cgattttatt cagccgatta tgctggattg acaggaaata tttatgaacg gagttgtgac
    19261 aaaagccttg tcgcagctcc tttttctgaa taaacggtgt gccagagata gcctatcggc
    19321 aataaggcac gattttgtaa aatatgggaa gcgatttttc aaaatcgctt cttatcgctc
    19381 aaggctgaac atctctgtca caacctctcc actaaatggt gtttaaaagc ttgcatctgc
    19441 gataataaga acaaccaaac gaaaaatagg aagcactatt ttagtttagt tgttcttatt
    19501 acttgatgca ggacagcttt ttcacaacct cttttttgta tagatgggca aaatttttgt
    19561 aataataggc gtatgtcttt ttcgttgagg agatgaaaaa gcatatggct tattttttgt
    19621 ttgctttgct tactttcttt ccacttcaag tggcagaaat atctactttt tattatgtaa
    19681 gcggaaccat atacttgaaa tcagaaggag atcatttcta tgaaaacaag aacaattgaa
    19741 atacttcaca gaatcatgac agcccaatat ccagtaaaag caaaacatct agcaagtgag
    19801 ttcaatgtca gtcagcggac gatccgtcag gaagttcttg aagcgaatat ctggttgagc
    19861 agtaaaaagc ttccggagat ccgtacaatt cgcaacaaag gttttttgtt gaagctggaa
    19921 aaggaaaagc aagctcgatt agaaactgaa ataaaagatg tgaaagacgg ctttttgaat
    19981 cggcgcgaac gtatttttga tctagtttta gccgttgctt acagccgaat cccgatccat
    20041 ctaaacaaaa aagaagaaga atttcaaatc tctaaaagta cattagatga agatatgaga
    20101 cggttacgag caacactggt cagttatggg atagagatcg tcagttatgg aaagcaagga
    20161 ctggtttata aaggttcaga acgatctatc cgtacgatga tctatgattt tatcaatcag
    20221 aatctgggaa tgaccgactt ctttatgaat caagatgcac aattaacacc ggctcaaaaa
    20281 atctttctcc attattttcc tttggtggaa atcaaaaaaa tacaggagat ctattccaat
    20341 aagttgttga aacaagaaga tgatatttat aaaaaacaaa tcctgctttt tacattgatc
    20401 tggatccagc gaatcaggaa acatgaattt atctctgcca ttaattggaa aaatacagaa
    20461 ataaaagaca gtagcttttc tgcatttatt gaccacatga tcgaggaatt tcaattggac
    20521 aatgtcccgc aagtagaaag aaattatctt cgtttcacta ttgagacgtt caatgctaga
    20581 gatatctcca attcaatcga gtgggtacaa gctcaattac taacgatcca attgatccaa
    20641 tttgtagaga acgagacaca cgtacctttc catctaaagg aagaagcttt attcgaaaat
    20701 ctctataagc acatggctgc actgattgta agaatcaaga atcatatcca agtcatgaat
    20761 ccattgaaag aaaacatccg aacaaattat ttcccaatct accgcgcagt cactcatttt
    20821 gttcctacga tcgaagaagt aattggtggc aagatactgg aggacgagat agcttttctt
    20881 gtcatccact tttcgacgat cgccagtgta atcaagcgag acttgaatta tgtttataaa
    20941 tcagtcgttg tctgtaacca tgggatggct actggaaatc tgttagcaga gaatctgaaa
    21001 gaaaagtttc ctcagatcga gattactgca gttttaagtt caaaagaaat cgaattagta
    21061 gataaattgg atgtcaatct ggttttcagc acctttcaat tgaattatcg aaataagccg
    21121 cttttagttg tcgatccgat tttaactgag acgaatatct tggttataga agactttttg
    21181 aaaagaaatg aagaactaca gcggttagag cctaacagtc atgaatcgac ggagttattc
    21241 actcaaataa tagatgtcat gaaagaaagt ggtggccgag tagatcgaat catctatggc
    21301 aagttagaaa aattattcga aacaaacaat ttagaaatca acaaaaggga gatccagcct
    21361 atgttaaaag atattttgac ggacagcaat atcatgatca aagaaaaagc cactacttgg
    21421 gaggaatcga ttgaactagc tgctagacca ttggttaaag aaaacattgt cgaagagcgc
    21481 tatgtcgaag cgatgattcg tgcagtgaat gattacggac cgtatatcgt gattggcaaa
    21541 cacatggcac tagcccatgc ccgaccagaa gatggggtca ataaattagg agtcagcgta
    21601 gctacgattg agcaaccaat cgatttcggt aatcctgaaa tggatccagt aaagattatt
    21661 ttttgtttgg cagcagtaga ctcctactcg catctgaaca tcatgaaaga actaattgaa
    21721 ttgatcaaca acgaagagaa gttggatcga ttgattgaat gcacaaatat cgaagatttc
    21781 aaacaactgc ttttttcagt agttgagaaa taataaatga tacgggggag aacaaagatg
    21841 aacaaattga acattttatt cgtatgcggt gcaggtttag gaagtagttt tgcagcacag
    21901 atgtctgctg aggatgtttt gaacaaatta ggagtagaag ccaaactgga ccattgtgat
    21961 atttcttccg cagtttccat gaaaccagat gtgatcatca cagcagaaaa ttttcgttcg
    22021 cagttcgaaa agttcgcagt tgatcctaaa acggcgatga tctatttgaa aaatattgtt
    22081 tcaaaaaatg aaattgaaga aaaaatcacc ccagttctgc aagataaggg agttatctaa
    22141 atacaaaaag aaaagagggt aaaa
//
LOCUS       DAFLVO010000049        21813 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.049, whole genome shotgun sequence.
ACCESSION   DAFLVO010000049 DAFLVO010000000
VERSION     DAFLVO010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21813
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.049"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(530..2026)
                     /gene="lysS"
                     /locus_tag="L1U99_001900"
     CDS             complement(530..2026)
                     /gene="lysS"
                     /locus_tag="L1U99_001900"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBN1212436.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2137..3141)
                     /gene="dusB"
                     /locus_tag="L1U99_001901"
     CDS             complement(2137..3141)
                     /gene="dusB"
                     /locus_tag="L1U99_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBN1212437.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3142..4029)
                     /gene="hslO"
                     /locus_tag="L1U99_001902"
     CDS             complement(3142..4029)
                     /gene="hslO"
                     /locus_tag="L1U99_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBN1212438.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4246..6357)
                     /gene="ftsH"
                     /locus_tag="L1U99_001903"
     CDS             complement(4246..6357)
                     /gene="ftsH"
                     /locus_tag="L1U99_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBN1212439.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6447..6992)
                     /gene="hpt"
                     /locus_tag="L1U99_001904"
     CDS             complement(6447..6992)
                     /gene="hpt"
                     /locus_tag="L1U99_001904"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBN1212440.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6992..8437)
                     /gene="tilS"
                     /locus_tag="L1U99_001905"
     CDS             complement(6992..8437)
                     /gene="tilS"
                     /locus_tag="L1U99_001905"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBN1212441.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8557..9027)
                     /locus_tag="L1U99_001906"
     CDS             complement(8557..9027)
                     /locus_tag="L1U99_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HBN1212442.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9073..9498)
                     /locus_tag="L1U99_001907"
     CDS             complement(9073..9498)
                     /locus_tag="L1U99_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBN1212443.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9565..9834)
                     /locus_tag="L1U99_001908"
     CDS             complement(9565..9834)
                     /locus_tag="L1U99_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBN1212444.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9845..11440)
                     /locus_tag="L1U99_001909"
     CDS             complement(9845..11440)
                     /locus_tag="L1U99_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBN1212445.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11455..14976)
                     /gene="mfd"
                     /locus_tag="L1U99_001910"
     CDS             complement(11455..14976)
                     /gene="mfd"
                     /locus_tag="L1U99_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBN1212446.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14993..15553)
                     /locus_tag="L1U99_001911"
     CDS             complement(14993..15553)
                     /locus_tag="L1U99_001911"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBN1212447.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15906..16880
                     /locus_tag="L1U99_001912"
     CDS             15906..16880
                     /locus_tag="L1U99_001912"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBN1212448.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            17050..18450
                     /locus_tag="L1U99_001913"
     CDS             17050..18450
                     /locus_tag="L1U99_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBN1212449.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18528..19250)
                     /locus_tag="L1U99_001914"
     CDS             complement(18528..19250)
                     /locus_tag="L1U99_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1212450.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19329..19835)
                     /locus_tag="L1U99_001915"
     CDS             complement(19329..19835)
                     /locus_tag="L1U99_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBN1212451.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19958..21757
                     /locus_tag="L1U99_001916"
     CDS             19958..21757
                     /locus_tag="L1U99_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBN1212452.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
BASE COUNT         6053 a         4752 c         3911 g         7097 t
ORIGIN      
        1 gagtgtttcc cgattcattt ttggctgccg tagcaacttt tatatcatat cagagagaca
       61 agcgattgtc aactcttttt taaaagtttt tttcgatttc gtttttcgaa atctttcggc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcgt
      241 tagtaacatg tcaataactt ttttgttatg tttttgaata aatattttct tctgtctttt
      301 ggacaagtaa taatatacca actaaattta gcttggtcaa cgaatttttt gtattttttc
      361 aagttttttt caataaacga ttattcataa cttttctttc tttatcgttc gttttcgtct
      421 tctttaatgt ctagaatagt cggcattagc ttttgaactt tcgttattat ttattccttt
      481 ctacacagca aaagctgcct aaggaattcc ttagacagct tttattcgat tatctcattg
      541 ttgggaatag caaaacatcc cgaattgatt gtgcatcagt tagcaacatt actaatctgt
      601 cgatcccgat gcctagacca ccagttggcg gcataccgta ttctaaggct tccaagaagt
      661 cttcgtctac accgtgagct tcgtcatttc ctagttcacg ttctttttct tgcgcttcga
      721 atctttctct ttgatcaatt ggatcgttca gttctgtaaa ggcattagca aattcgcgcc
      781 ccactatgaa tagttcgaat cgatctgtga atcgaggatc ttctggattt ttcttcgcta
      841 aaggcgaaac ttcgactgga tgtccgtata caaacgtcgg ttgtgtcaat gtttcttcaa
      901 caaatgtttc aaagaattca ttgataacat gtccgacacc catagcttcg gttacttcta
      961 cattgtgttt ttcggctaaa gctaatgctt cttccaatgt catttcttgc cagaagtcta
     1021 caccagtttg ttctttgatt gcatctacca tatggatgcg tttaaagtca ctttctaagt
     1081 cgacagcttg tccatcatat gtgatttttg ctgttcctag tactttttca gctgcgttac
     1141 ggataatacc ttctgtcaga ttcattacat cattgaaatc agtatatgct gtgtatgctt
     1201 ctaacatcgt aaattctgga ttatgtgtag tatcaattcc ttcattacgg aaaacgcggc
     1261 cgatttcata aactttttcc attccgccaa caattagtcg ttttaaatga agttctagcg
     1321 caatacgcaa atataaatca atgtccagtg cattatgatg cgtgataaat gggcgtgcgg
     1381 cagctccacc tgcctcattg tgcaatactg gtgtttctac ttcaatatag ccattgccat
     1441 ctaaatagcg acggatttcg ctgataattt ggcttcgttt cataaatcgg tcaaagcttt
     1501 cgcgattact gattaaatcc aagtagcgtt gtctgtagcg ttgttcaata ttcgttaagc
     1561 catggtattt atctggcagt ggacgaagtg cttttgacaa aatcgtgatt tctgaagctt
     1621 tgatagaaac ttcgcctgtg tctgttttca tgatttgtcc agttacacca aagaaatctc
     1681 caaggtctgc atgtttgaat acttcatagg cctcatcacc tacttggtct tttcttacat
     1741 aaatttgaat ttggccttca cgatcttgta gatgcgcaaa tccagctttc ccttttcctc
     1801 ggcgagtcat catacgacca gctacactag cggtcaatcc catttctgct agttcttctt
     1861 ttgttcttgg atcaaatagt tcatgcaatt cttctgagtt gtgcgtgcgt tcaaatcgtt
     1921 ttccaaatgg atcgattcca tcttcacgca attgttccat tttttgacga cgtacaagca
     1981 tttgatcatt taaatcttct acttgatgtt gttgttcctg tgtcacaaaa gttcctccat
     2041 tctcatgtta atctctttcc tataatgcca atgaaacaca aaaaaagcaa gccgaacttg
     2101 gaatttcggc ttgaaaattc acgaaaaact tagaaatcac aacgtttgtt tcaatagtac
     2161 tttttccgct ttttctacaa attgatccag caggtcattg atttcttgct gtttttctgt
     2221 ctgattgatt gctactttca ctttcgctgc tcgaggaatc ccttttaaat aataagccgc
     2281 atgtgttctg aattctctac aagctacttt ttctcctttg agatctgcta agcgttgtaa
     2341 atgaagttta gctgtagcaa ttttttcggc tggtgttggt tcaggaatca gttcccctgt
     2401 ttcgagataa tgctgtgtgc ggtgaatcat ccatggattg cccagcgctg cacgaccaat
     2461 catcacaccg tctgcaccga catagtcaag catccatttt gcatcttctg gcgttttgac
     2521 atccccgttc cccataaatg gaatcgtcaa atgttttttc acttctttca atacttccca
     2581 gtccgctttt ccttcataca tctgaacccg tgtacgtcca tgcatagcga tggcacttgc
     2641 tccagctgat tgtgctgcta atgcattttc tacagcaaag acgtgctctt catcccaacc
     2701 aatacgcatc ttgattgtta ctgggatatt tactgctgaa gaaacagctt ggaccatttc
     2761 gtatactttc tcaggatcta aaagccattt tgctcctgct tctgctttga ttactttatt
     2821 tactggacag cccatattga tatctattat atcggcagct gtgttttctt cgacaaattg
     2881 agcagcttca actagactat ctttatttcc gccaaatatc tgtaaactta atggatgttc
     2941 tgtttcttca atgtggagca tctctaaagt ttttttgttt ctgaaatgaa taccttggtc
     3001 actgatcatt tcacatacga ctaagcccgc accaaattct ttgacagtga ctcgaaatgc
     3061 tgaatttgtt attccagcca tcggtgcaac aacgacacga ttagggattt ccacattgcc
     3121 aattttccat gtgtgttcca cttaaatccc tcctaaggct tctttcttca atccatctaa
     3181 ttcttcttcg ctatacttgt atttgttatt acagaaagaa caaaccgctt ctgcaccgtg
     3241 atcttcgtct atcattgctt ggatttcttc tgcacctaac gcgataattg cttctgcaaa
     3301 tttttctttt gaacagtcac atttgaattg aacaggcatt ttttccaaaa tgttcaattc
     3361 ttctgtacca agcaatcctt tcaatatttc ttctggtgtc tgtccttcat ctaagagggt
     3421 agagattctt ggtgtcgttt ttaattgttc ttcgatcttg ctgattgttt cttcatcggc
     3481 acctggcatg atttggatca tgaatcctcc cgccgtcttg atgctgtcgt cagtattgac
     3541 caatacactc agtccaacag ctgaagggat ttgttctgag atagcaagat agtaagtaaa
     3601 atcttcagcg atttctccag aaacaatcgg cgtttgccca gaaaaaggtt cttttaatcc
     3661 taagtctttt gtgacagtaa acattccttg tgttccaact gctccccgca catcgatttt
     3721 accttcacta tttagaggaa gactgagatg cggatttttg atgtaacctt tcacatctcc
     3781 ctttccattt gcatctacta caattcctgt tgctggacca tcgccttgga ttcgaacagt
     3841 tagtttgtct tctcctttga gcgtcgcacc aagtagcaga ctaccgacca atgtccgtcc
     3901 caaagcagct gaggaggtgt gccaagtatc atgacgtctt tgtgcctccg ctacggtatt
     3961 tgttgcttga acggcgtatg ctcggacgaa tccgtcgtga gcaagtgcct taaccaaata
     4021 atctttcatt tgttatgtac tcctttttcc gtttttaaac tcatagtgaa tcatactagc
     4081 aactactgct tttttcaact ttggaatgct tcttttaaaa ataattcaga atcatctaga
     4141 aaacaggaca tcaccctatt tacaacttaa ataaagaaat ctcccgaaaa ccggtttttg
     4201 ttccggtttt cgggagtcat atcagatcaa ttgacctata tttttttatt tgtattgatc
     4261 gtctgaatga ttatcttctg attgttgaga atctgaatca tgttctgctt tattttcctc
     4321 attcagttca tgttttgctt cttcaaaatc acgtttttct tccgcttgtt tttcagcgtc
     4381 tttttcttcc aaagcacgtt ttgcttcttc aaaagttttc gcttcttttt cgcttggata
     4441 atcatttgac tcagtacctt caggcatcac accgtgttca aacaatgact tgattgcttt
     4501 ggcatccaat gtttcgaatt ccaaaagttt ttcagcaatc agtttatgct gtgcacgatg
     4561 agcttcgatg atttctcgag ctttatcatg agcttccatc aagatttttc gtacttcttg
     4621 atcaatctcg aaagcgactt gttccgagta agcttttgtt tgaccatagt cgcggccaac
     4681 aaacacttga tggtttcctt catattgaac aggacctaaa cgatcactca ttccatattc
     4741 tgttaccatg cttcgtgcta gagctgtcgc ttgctcaaag tcattggaag caccagttga
     4801 ttggacattg aagatgattt cttcagctgt acgtccacca agtaagccta cgatttgttc
     4861 aaacatatct tctttcgtca tcaagaactg atcttctttt ggtaaagcga tcatatatcc
     4921 gccggcgcgt ccgcgaggga tgatcgttac tttgtggacg acccgagcgc gactcaatac
     4981 taatccgaca atcgtatgac cagcttcgtg ataagcaacc atttcgcgtt cttttttgct
     5041 gattacgcga tcttttttag ctggacctgc aatcacgcga tcttccgctt catcgatatc
     5101 agaagcatcg attttctttt tatttcttct agcagctact aacgctgctt cattcaagac
     5161 attttctaaa tctgctccgg caaaacctgg tgtctgttga gccacaactt tcaagtcaac
     5221 gtcatctgcc atcggtttat tccgtgcatg gactcgcaag attgcttcac gaccttttac
     5281 atctggacgt ccaactaaaa tctggcggtc aaaacggcct ggacgtagta acgctgggtc
     5341 tagtacatca gaacggttgg ttgcagcaat gacgattact ccttcatttc cgtcgaagcc
     5401 atccatttct acaagcaatt ggttcaatgt ttgttcgcgt tcatcatgtc cgccgcccat
     5461 accggcacca cgttgacgac ctaccgcatc aatttcatca atgaaaatga tagctggtgc
     5521 gtttttcttc gctgtttcaa acaaatcacg aacacgactt gctccaacac cgacaaacat
     5581 ttctacgaaa tcagaacccg agatcgagta aaacggtact ccagcttctc cggcaacagc
     5641 ttttgctaat aaggttttac ctgttcctgg aggtccttct aaaagtacac ctgccgggat
     5701 acgggcacct aattcaacaa atcggcgagg atctttcaga aattcaacaa cttcaactag
     5761 ttcttgtttt tcttcttccg cacccgctac atcagaaaaa cgtacgcgat tagctttttt
     5821 gtctgcttct ttggcttttg atttaccaaa gttcatgaca cggccgccac cgccaccgcc
     5881 gccgccttgt tgtcccatca tcatgtaaaa gaaaaagatg atgattacga ttggcaagaa
     5941 gctaagcaat agggaaaccc atataccgct gcttgattct tcttttactg ttgtagcaac
     6001 tttgttttct tttgccagtt ctgttacttg gctcaatgtt gtatcatttg gcaaaatgat
     6061 tgttgtgaaa tgggtagtag tcgtatctgt tgaacctaag atagctaacc caccgctgtt
     6121 agcgacggtc tgctgttctt tgtattcacc agtgatctta tatacaccat ttgcaggctg
     6181 cacttcaaat tctttgatct tgcctgcttg tagttgttct gtgaattttg agtactcgat
     6241 atctgacgat cgctggccgt tattaccaaa aatgaaataa acgaccatta ccatcgctaa
     6301 gattacgagg acataataca aggcattttt catcatgccg ttgttctttt tgttcatagt
     6361 tgccctccct aagcgtcaat ttaatttaac agttttttat caatcctgac cattctattg
     6421 taccataatt taattgagat acagcattaa tttgattgat aaacactagg tttcaataca
     6481 ccgatgtacg gaaggttacg atatgcttct gcataatcca agccataacc gaccacaaat
     6541 tcatttggta cgttgaagcc aacataatct gcttcgatat ttactactct tccttcaggt
     6601 ttgtcaagta gtgtaacaat tttgactgat tttgctttgc ggtatttgaa aagatccact
     6661 aaataagcaa gtgttcttcc gctgtcaatg atatcttcaa cgatcaacag atcgcgacct
     6721 tctacattcg tatctaagtc tttgacgatt tttacttccc ctgacgagac tgttgcattc
     6781 ccgtagcttg aaacatccat gaaatccaat tccaaatacg tatcgataga acgaacgata
     6841 tctgccatga atggtaccgc tccttttaag acacctacta ctaggggatt ggtgttttgg
     6901 taaatttctg ttaactcttt gcctagttct ttgcaacgaa cttgtatctc ttcttgtgag
     6961 atcaaaattc tctcaatatc cttttccaac atcaggttct ccttccaatt gcttcttttt
     7021 gatatttgta aagaagtatg tagtgtattt tatcagtttc ttcacgaata ctcaaatatg
     7081 aaaaggcaaa aggtatcaag ctatatatat ttcttttggc atctgtaatg atccaagcat
     7141 gctgcctttg tgaattaggt actttctgat cgataaaata tctagatact ttttttgtga
     7201 gattctctgt taatttaatg cggtctcctg cttttctttt ttcgacatac agttgcacat
     7261 cagcaggaat ccaaatgtca tgagaaaata gagaccatga atctgttgct ttgatgtccc
     7321 ctgcattttc aggtttgacc agaccaatcc attctgtttc attcaaatat attccttgtt
     7381 ctggaatcag caacaagcgc tggtcttctg tctggctagt tgcttgtttt tcttttttag
     7441 agagtacaac aaaatgatac tctcttttca gtatccaatt attgccaata ctgagttgcc
     7501 attggctttt tttctgttgc cactggtcta aaatcgactc catttgttgt tctttcaaaa
     7561 taattcctgt ttttgagaat gctttgtcga aaaaggagta aaaaaaatag tatcgttcag
     7621 catctgtcat ttcttcaatc atttctgcag aaaatcgaaa ttgttcctcc cactgttcga
     7681 cttccttttc gatcaactgt cccatatatt tttgaatgac ttggtctgcc cattggatct
     7741 gttgcgaaaa ttgctggaaa tgtctcaacg cctgtgtatt ttcttgtttc aattgaggaa
     7801 ctaccaaatg acgaagccga tttctctgga tatctaacaa ttggtttgtc tgatcctcaa
     7861 agtaaacaag ctgcgattcc gctgcataag tatataggtc ttctttgcta aaactcagca
     7921 acggacgaat cagtctgccc gtagcaaatg gttgtacttc tttgattcca gaaaaagtat
     7981 ttaactgtcc cccacgaacg attttcatta acaccgtctc gatttgatca tctccgtgat
     8041 gagcagtcat caacgtgtca tattgtcctt cttccatcac gcgagtgaat tcttgataac
     8101 gaaagttacg agcttctgtt tctatggcgg atttggctgg atcttcccaa atacttacat
     8161 ataaagggag attcttctct tcacaatatg agcgaagata ggcagcttct tctgctgatt
     8221 cttctcttaa ttggtgattg atgtggacga tacctaaaga aaaaccgatt tggcgttgca
     8281 cttgtaaaag taaatggagc aaaaccatcg aatcaacacc acctgatacc gctgctaaaa
     8341 ttctcgatcc ttgttgccag aatccttgtt cattcccgtg ccgaataaat gactgctgta
     8401 atagcggtgc ttttttcccg cctttttcaa cgttcatcct ttccacaccc tttcttccta
     8461 aaaaaaagag agcgggaaaa cgtctaaaac gacaattaac ctgccctctg ttgatactat
     8521 gacccaaata gtcgcactat cattatttgc ggctttttag ctgcgacgtc cgccacggcc
     8581 accgcgcttt ccttctgtgt ttcgcttcaa tgaagataag cggtcatcgc tatctttcaa
     8641 aaatgaactc atcaatgaat cgaagtcttc tttttgagct gaaggttgac tgcgagaaaa
     8701 agattttttc tgtgctggac gatttcggtt gtcacgggga tctttttgtt gatatttttt
     8761 aggacggctt tcttctccag attcagcagg ttgttcctgc gctttccgga tagatagtcc
     8821 gatttttcca tcatcattta ctgaaataac tttaactgtt acttcatctc ctacacttaa
     8881 aacatcatgg atgtctttta catagccatt tgacacttcg ctaatatgaa ctagacccgt
     8941 ttttccagca cctagatcaa taaacgcacc aaaatttgtg attcctgata cttttccttg
     9001 cagttttgct cctacctcga ttgacataaa aaaaatgttc ctcctaatta tttccctttt
     9061 ttatattcct gcttattttg cagttgtaga actagttgat tgatctgttt catttgtcga
     9121 gctgtctgta tttgattcta atataggata aactttttca ccgtcttttg agtaaaagaa
     9181 tttgcttctg gcaagtttag ctacatactc atcatctttc agcaatgaaa catcttggtg
     9241 cagctgatca acgtctgcgt tgacttcttt catttcagta tttgcttcga ctctcaattc
     9301 gttcaattga tgcatccttt gcatgtcatg gaaaatctgc acacctatta tcgcgaaaat
     9361 gaccaaagca ccaacaaaaa ttgcagccag tctgcgtctt cgaaaaatca gttgacgttg
     9421 ttgttgctga aattcagcat actttttctt tgcatattcc gtatctagcg cagcgatttt
     9481 attgcttttt ttcgtcactt ggattcgctc caatcttttt gattgtcttt ttcattatac
     9541 caatatcgtg aaagcttgtc taatctattt ctctagtgtt tctgtgcgat tttcagaaat
     9601 aatttcgtac attttttgtg catcttcttt tttggttgat tcatgtaatt ccgtaatttt
     9661 cacttccaac gttttgttgc caaactggac tttcaaaata tcgcctactt tgacatcact
     9721 ggaagatttc gccaatttac cgttgatttg aattcttcct ttatcagcta cttcttttgc
     9781 tactgatcgt cttttgatga ttcgggaaat ttttaaaaat ttatctaatc gcatatctta
     9841 ttcctcactt tttaattttt ttatttaatc gcaggatttt cttaccaaaa ggcaacatta
     9901 gccattctcg tactgtaaac agacgaagac gaatcactgc ataaatgaac acagaagccc
     9961 cgatcccaac tcctatcacg ctgacaaaaa aagcagtgga acgatgagtt acaggaccaa
    10021 atactatatt caatacacca taatacagca gcagtactac tgtcatacaa agaaggctga
    10081 acatcaactt ccgtccaaaa tgccgttctt tccaaaaagc atttagctct tttgtttcaa
    10141 ttcgaacaaa ataccaaagc gtcacaccta atcctaaaag ggtagacagg cttgcacctg
    10201 ctgttcctaa taaaccggtc agaaaagaag tagtcaatcc ttttaccaat agtccccatc
    10261 ctgcgccttt taaagaaggg cgaaacgagt tcttgctttg agcaatactt tgataagctt
    10321 ggatgactgc agtgaaagca atggaaaaaa caaataatac aagcgctgca tttcccgcat
    10381 aatctttaaa caacgcataa ttgatataag ggagcagcaa ggctaatccc aaagacgcag
    10441 ctaatgctaa agcggtcgtc aatctaagat agattttggc tgtctgtaaa aactgacgat
    10501 agatccggtt ggtcaaatga cgagtcaacg caggcaggaa tgtcgcactt aatgcagtgg
    10561 caatcactaa acctaattgt actaaaggct gacctcgatc atagacccct tttgctatct
    10621 tcgcaccgta ttctgacagt ccgtaaactt ccaaagcatt ttttacaaag aaagagtcga
    10681 tcagctggaa aaagataagc aatccactat aaatcgaaac cagtccgcct tctaccagaa
    10741 aacgccggat caagggcttt gacggctgtt tgaacaatgg aaaccgtcgg aagcttaacg
    10801 ctcctccatg aatcttttgt tcatagtagt gaaggatccc atatgcgcat aaaccgccaa
    10861 aaacagctcc actcattgct gccgtccctg tttggtacac cgtccatcca agctttctaa
    10921 aagcaaacgc actacagaca atcacaaaaa cacgaacgaa ctgctcaact acttgagaaa
    10981 cagcagttgg ttccatcaag aatcttcctt ggaaattccc tcgataaaaa gatagaccag
    11041 gcatcagcaa aaaggtaaag gaaactactt ggatcagcgg tttcaattgt atgtctccca
    11101 tcatccaagc aatccagctg ctaaatgcaa agacaaacaa ccacaaaaag acacctgtcc
    11161 aaaatactaa gggataaaga ttttgcaaag cttgctttcg ctcgaaagga ttctttcttt
    11221 ctgcaacgta ctttgatatg aactgcggaa gaccggataa agctaaagtc attgctatcc
    11281 cataaattgg ataaacttgc tgataaacat aaaaaccttc gtcgccgact aagttttgga
    11341 ggggaattcg gtaaagggca cttaatactt ttgctatgaa agaagcaatc gtcaatacaa
    11401 atgctccttg catgacgcgc cgcatttctt tatgatccaa atcattgctc cttcctacgc
    11461 tgacagatat ttttgctcac gcaacgcttt gacaaacttt tggatttcct gaagccatac
    11521 tgcttcttcc atttggttgg ggatcgtcaa gcgtatcacc atctgttctt tttcaacgcc
    11581 tagactggct tttagttttg tcgctgtcag tgcttcgaat aactgttcca cactatagcg
    11641 ttttgttcca actttactta gagtaaagac tatatgcgcc tcctgtttcc ttatcgtttc
    11701 taggagcgct cgatcgccat ccattttgat ctgcccaatt gtcaagagat gtgctacttc
    11761 ttctggatat tctccaaaac ggtcgagcag atcatcttct agttcatcta gcatttcttg
    11821 cgaatcaagt tcacgaattc gtttatagat ctcgattttc tgccgttgat ctgccacgta
    11881 tgtttcaggt agatacgcat cgacaccgag gtcgatctca acagtggtct tctccacttg
    11941 actattcttt ccttgtttac gagaaacagc ttcgcttagc atttgagaat acatatcgaa
    12001 accgactgca tcaataaatc catgctgctg agcacctaag agattacctg caccgcgaat
    12061 ggaaagatcc cgcatcgcaa tcttgaatcc agatcccagt tctgtaaaat ctttgattgc
    12121 ctgaagacgt ttttcactga cttcgttaag gatcttctgc tgctcataca taaagtaagc
    12181 atatgcgaca cggctgcttc ttcctacccg ccctcgcaat tggtataacg tggataatcc
    12241 catataatca gcgttctcaa cgaacaacgt atttgcgttc gggatatcta ctcctgtttc
    12301 aatgatggtt gtagtgacaa gaacatcata ttgaccttca ataaattcaa aaagcgtatt
    12361 ttctaattgc gcctctgtca tttgcccatg agcataaccg atccgtgctt ccggaacgag
    12421 ttcttggatt tcttctactt tttgttcgat cgtttctacc cgattatata aatagaatac
    12481 ttgtccacct cgtcccattt ctcgatggat tgcttcgcga atagccccag gatttttttc
    12541 cataacatac gtttggatcg gataacgatt cgcaggcggt gtttcgatta ctgaaagatc
    12601 ccgcacgcct aacatcgaca tatgcaaagt tctcggaatc ggtgttgcag tcagagtcaa
    12661 aacatccact tgtgcacgta actgtttcaa tcgttcctta tgttttacac caaaacgttg
    12721 ttcttcgtca atgatcagta gacccaaatc gctaaattca atatcttttg acaaaattcg
    12781 gtgggttcct acaacaatat caacttgacc tgtacgcagt tgttcgatgg tttctttttg
    12841 ttgctttctt gttctgaaac gacttaatag cccgatattt acggggaaac cttcaaatct
    12901 ttccagcatc gtttcatagt gctgctgtgc caagatcgtt gttggaacta aaaaggctac
    12961 ttgtttgctt tcctttatcg ctttaaaggc cgctcgaagc gctacttctg ttttcccata
    13021 accaacatca cctacgagta gtcgatccat tggtttttct ttttccatat cccgtttgat
    13081 ctccgctgca cttctcaact ggtcatcagt ttcagagtag gggaaggcat tttcgaattc
    13141 tttttggtag gcgtcatcag gtccaaaagc atatcctttt tctgactctc ttgcggcata
    13201 taatttgatt agatcgtcag cgatatcctc gatttttgaa gagacttttc gcttggtttt
    13261 cgtccattca cttccgccta gcttattgat gcgaggcgct ttggcttcag aggcgacata
    13321 tttttggatc agattcagtt gagtaacagg aataaacagt ttgtcgtcgt tttgatacaa
    13381 aatagtcata tagtcttggt gaacgccatc tacttctagc gtttccatcc caatgtattt
    13441 cccgatacca tgattggcat ggacaacgta atctcctgct tttaactcat tatagctttt
    13501 caatcgctct gcgtttgtta ctgtttgacg tctcgtttgt tttttcgtcg ttttttggaa
    13561 aatttctttt tctgtgatag ctactatttt ttcttgagga agttcaaaac cagcctgcaa
    13621 agctccttca actaattgta cctgtcctct gatcaatgca tttttttctg tttctactac
    13681 taatatgtct tcatctcgaa gcatttgttc tgctttgcgt attctgtcct ttgtcggaat
    13741 aaagatcaca acagtctgtt tttgcttgcg ccaacggtcc atttctgttt tcagcaatgg
    13801 catttgtccg aagaactgtt gcatcgtccg atattgaaaa ttatggattg cttggaaacg
    13861 aagatttccc atcccttttt ggaagagtga gaaaaaggtt gtggtgaact tttccttctg
    13921 cacgattttt tgtatatctg ctgaaaatgt ctgctcagaa aacacccgca attcgctgat
    13981 tttttgagtc tgccattctg ccgcttccct ttcgatttcc cgatttgttt ccatgattcg
    14041 ctgataatca tcaacgacta gtaaactatt tgaagggaaa taatccaaga tcgtcacaga
    14101 ttcttggtaa agaagatctg agtagaattt tgcttcttct gtcgggacac ctgcttgcca
    14161 gcttgaagtc agctgaccga agtaatcttg caaaaactcg cggtctgctt cttctgtggt
    14221 cgcagcaagc cgtttttcta gcattttttg catttgctct attccatgtt ctagatcctc
    14281 tggtccgtag acttgttcac tcgttgggga aacccagatt tcttccgttt tttcgattga
    14341 gcgttgtgtt tctgcttcaa aataccgcat agaatctatc tctacatcaa atagttctac
    14401 acgaacagga taggttgtcg ttaacgggta aatatcgata atgcttcctc gaatactgaa
    14461 ttctcccggt tttgcgacca tctcttctcg tacatagccc atcaaagtca attggcgagg
    14521 aagattttcc acgtctatct catcaccaat atgccaattc aattgcgcct gtagccaagt
    14581 tttcttattc ggcagtcgtt tgtgcaaaga tgcgactggc aacaaataga tacctgcttt
    14641 tttttcttga agtgcgttaa gcgttgcaac tctctcgcct cgcgcttctg gagaagaaaa
    14701 ggccatttca gcagaaagca cttcatccac tggaaataaa tggatctgat cttgcggaat
    14761 cacatgttgc agatcttctg ctaactgatt cgcataatac aaatttggca tcagaataat
    14821 catgttttta tttgttttct taaacgctcg agcaaataga agtgttttcg ctgagcccgc
    14881 taatcctgtg attagttgtc taggcatttt ttcttctaaa ttgctgaccc attcttttac
    14941 ttgcggatct tttccgacta attgaataat atccattcct tttcctcctt cctcaattga
    15001 atcgattcat cgcatccacg aacgaatgcc cttctatgag atattcgact gctttaacag
    15061 attgacacat gctttcttct atcaaaggct gattttcttt gctgaaagga ctaagcacat
    15121 gctggactac tgtttttttc ccttctggcc tgccgattcc caccttgatt cgatcaaaga
    15181 cattcgtatt caaatgggaa ataatacttt tgataccgtt atgcccgccg gcacttccct
    15241 tttgacggag ccggattttt cccactgcca gatccaaatc atcgtagatt acgactaatt
    15301 cctctggata aatcccaaaa taagtcatta gtgggccgac tgcacgacca gattcattca
    15361 tgaatgtttg tggtttgact aaaaggatct tttctccatt atgaaaaaat tcggcaactt
    15421 ctgcttcgaa cggatttttt ttgaaagtag cttgatgctc gcgtgcaatt ttatccacga
    15481 ccataaagcc gatattgtgt tttgtatatt ggtatttggt acctgggttt cctaacccga
    15541 cgatcatttt catttttgtt ttccacctaa ttctaaaaag cagcacaaaa ggctggactg
    15601 ctaattagcg gtccagtcca tcgagctttt ttctttttta cacttgtcaa tgcatagtat
    15661 aacacaaaac aaggcgtttc ggctaaaaga gaatcgttaa taaatgataa agaaattaaa
    15721 aatttcttca aagtttaatg aaataattga tatataaaaa tagtgaaata acgcacatgt
    15781 aagcttttac atataataca accttgttat ctgttatatt ttatagccaa atagcgtgac
    15841 atggggcttg agaaatgtta gcataagcat gggaaaaaac aaatcaatgg aaggattgat
    15901 actaaatgac tgcagctgca gaaaaaaaag atcatcaaaa agttattctt gttggagacg
    15961 gcgccgtagg ttctagctat gcctttgctc tagttactca aaatatcgct caagaagtag
    16021 gtattgtgga tatcaatact gctaaaactg aaggagacgc aattgacttg tctcacgctt
    16081 tggcatttac ttcacctaaa aaaatctatt ctgctactta cgcagacgca catgatgctg
    16141 acttagttgt tattacagct ggcgcaccac aaaaaccagg tgaaactcgt ttagacttag
    16201 taaacaaaaa cctaaaaatc aaccgcgatg ttgtcacaca aatcgttgaa tcaggattta
    16261 acggtatctt tttagttgcc gctaacccag tagatatttt gacttactca acttggaaat
    16321 tctcaggttt ccctaaagaa cgcgtaatcg gttcaggtac ctctcttgac tcagctcgtt
    16381 tccgtcaagc acttgcggaa ttagttgacg ttgatgcacg taacgtccat gcttacatct
    16441 taggtgaaca cggagattca gaattcccag tttggtcaca tgcaaatgtt gccggcttgc
    16501 aaatctatga atgggtaaaa aacaacccag aaatcgatga agaagctatg gttaacctat
    16561 tctttggcgt acgtgacgct gcttacacaa ttatcgagaa aaaaggcgct actttctatg
    16621 gtatcgcagt agcattagca cgtatcactc gtgccatctt agatgatgaa aatgctgttc
    16681 ttcctttatc agtattcatg aatggcgaat atggattgaa cgacatctac attggtgcac
    16741 ctgctgttat caaccgtcaa ggtatccaaa aagtaatcga aattccttta agtgacagcg
    16801 agcaagaccg tatggctgct tctgctaagc aattaaaaga aattctagat gaagcttttg
    16861 ctaaactaga cgctgaataa tctttgaaca tgacggaaaa catctattcg gtgttttccg
    16921 tttttttatt ttatcaccct tatggtttct aaattttttc ataaagtaga gataaccttc
    16981 gtcttttcct ctaaattatg ctatcatgag accgttccac cctaaacttt tacttaagga
    17041 gttgtcgata tgacaagatc ttcgcatcga aaaaaatcga aacatgttgc tttgctttca
    17101 gttcttggtg ttctcttagt gctgatcagc ttttatacct atcgcagtac atactacaca
    17161 aagcattttt tgccgaatac agaaataaat ggaataaatg tcagcaatct aacagtcgaa
    17221 aaagcaaatg aaaaattaaa agaagcttat tctgataaaa aactggctat taaagaagat
    17281 ggaaaagtct ggcaggaagt accaaaatcc gagctcggct acaaagatga tttcacttcg
    17341 gagctttctc cgatcctaaa tgaacaaaac ggatggactt ggggaatgac ttatgtctca
    17401 gcggcagaaa aacaagaaat agatcctgtc agtcaaaacc accaaaaact agacactacc
    17461 gttcagacat tgacaactaa gctgactgat ttgaacaaag accggacacc tactactgat
    17521 gcaacgatcg aaaaagcagg tgactctttc gttatcaagc ctgaagtcaa tggaaatacg
    17581 atcgacgtcg atgctgcggt caaacaatta aaaagtgcgg taaactctgg taaagataca
    17641 attgaattga ctgaattcaa agaaaaacca aaagtaacat ctgaagacag ctcactgaaa
    17701 gaacaactcg catccatgaa tgctatcgca aatgtaaaag ctacttacag tataaacggt
    17761 gagactttcc agatcccatc aagtgatatt atgagttggc tgacctacaa tgatggaaaa
    17821 gtcgatttag atacagaaca agtacgtcaa tatgtaacag atttaggcac aaagtataac
    17881 acaagtacga atgacacaaa atttaaaagt acaaaaagag gagaagttac ggtcccagtt
    17941 ggcacttaca gttggacgat ccaaacagac agtgagacag aagcattgaa aaaagcgatt
    18001 ctggcaggcc aagattttac tcgttcaccc attgtgcaag gtggcacaac cgctgatcat
    18061 ccattgatcg aagatacgta tatcgaagtt gatctggaga accagcatat gtggtattac
    18121 aaagacggaa aagtggccct tgaaacagat atcgtttccg gaaagccaac tacacctaca
    18181 cctgctggag tcttctatgt ttggaataaa gaagaagatg caactttaaa aggaacaaat
    18241 gacgatggaa caccttacga gagtccggta aactactgga tgccgattga ctggacaggt
    18301 gttggtatcc acgattcaga ctggcaacct gaatacggtg gagacttatg gaaaacccgc
    18361 ggttcacacg gctgcatcaa caccccacca agtgtaatga aggaattatt cgggatggtc
    18421 gaaaaaggaa cgcctgtatt ggtcttctaa caaaaataat atataaaaag aaagcacccg
    18481 tacgattggt acaggtgctt tctttttatt atctaacaat gtgctactta catttcagca
    18541 gcagtaaaga cttctgaaac atcatcatcg tcttctagct tatctactag acgttccaat
    18601 tgctcttttt gttcctcatt taaatcaatc gtcgtttgtg gaatcatcgt caattctgct
    18661 tgcgccaaag tgaactcttt ttccaactca tctcgtacag cagcaaaatc ttctggtgca
    18721 gtataaatct cgaatacttc aggagaagtt tgcagatctt ctgcccccgc ctctaataca
    18781 tcctcaaaca tcgtctcttc atcaacagtc aacccatcgc gttcaatagc gatatatcct
    18841 ttgcggtcaa acaagtaact gactgaaccc gtttctccca gtgatccacc gtttcgagta
    18901 aaagctactc ggacatttgt cgctgtccga ttacggttat ctgtcaatgc atggactaag
    18961 attcctactc cacccggacc atatccttca tacgtgattt catcgtaatt cgtttcatct
    19021 acggcactcg tagccttttt aatcgcccgt tccacattgt cgttaggcat atttgcagct
    19081 tttgctttgt ccacaacaag ccgcaaagct ggattcatag atggatcagg accgcctgct
    19141 ttagctgcca tataaatttc acgagaaagt ttctgaaaga ctttccctcg ttttgcatct
    19201 tgggcatttt ttcttccttg gatattatgc catttactat gtcctgacat gatttttcct
    19261 cccttgttct tttgagaata cacttctatt ctagtactat ttcacaaaaa aacaaagcca
    19321 cagccaatct ataaacgctt cttgaatgcc gcaaaaagca cacataatat cacagcagtc
    19381 agagcaccga tcgaatccaa catgacatct tggaacatag gtgttcgtcc accggtcatc
    19441 atctgatgga attcgtccaa acctgcgtac cctgttgctg aaagccaagc aaggatcgct
    19501 gtcagccacc aaatttttag cttggggaaa acacctaaaa acaagctgcc tcccaaaata
    19561 aaataggtac cgaaatgtgc gcccttcctt aaaaagaact ctaaaaattt ggcgtagccc
    19621 agatggttga tactcaccat acttccacca taattaaaac gtatacccgc taatgtgtct
    19681 ttaaatggct gattaggcag ccagctttct aatcgcgaaa cttgtgattg ctgtccgtaa
    19741 gtttgagaag aactgtaaaa taagattata acgactatca gtgcgattac taaataaata
    19801 tttccgtttt tcatttgttt ttttgaagaa ttcataagtc acctctgtat tttatcttag
    19861 actttttttg aagaaacaac aatcattttc atagagactt cttccataaa aaagtgctat
    19921 acttaatttt gtattacaat atgaagggag ttttttcatg agttattcat taaattggaa
    19981 tctagattct attttttccg gaggcagtca ttctgatgct ttgaaccaac ggatgaagca
    20041 attggaagac caaatgaacg agtattatca ccgcgtaaca aaatggtcac ctagttctga
    20101 caatgcagag cagttaaacg ctattcttca attgcaagaa acgattacga atggttttac
    20161 ccaatgcagc agctatatta ctgcattgct ttctgccaat gtcaatgatt cagatgcaaa
    20221 ggtcttatca ggcaagcttt acgcaatgct gcctcgtctg caatcagccg aaactgtatt
    20281 gtcaaagaaa tttgcagaaa tatctgacaa tgattggaat cagatgcttt ctcaatcttc
    20341 gtttgaaaca attgcttttc gtttaaacga gattcgtcgt gatggctcac aattattatc
    20401 agaagctgaa gaaaacatta taaatacgct ttctttagat ggtctaaatg cttggagcag
    20461 tcattatgat acgattgtag ccagcatttc gattcccttc gaacaagatg gacaagtagt
    20521 cgaattatct gctggacaag ccttcaataa gatgatgggc gatccagatc caaaagtcag
    20581 agaaacactt ttcgcagcat gggaagaagc ctggaaagaa aaggcacccc tcttcacgga
    20641 tactttgaat catttagatg gttttagact ttctgactat gaacttcatg gtgtcacaga
    20701 ttttctacaa aaaccattag agtacaatcg gttgaagaaa gaaacattgt ctgtcatgtg
    20761 ggatacaatc cagaaaaaca aacaacccct tgttaattac ttgactagaa aagctaatct
    20821 tttcggtaaa gaaaaaatgg aatggcaaga tcaagatgca cctattattt taggcgattt
    20881 gaaagaaaaa acctttagtt ttgacgaagc agcagcattt attatcgaaa actttaacaa
    20941 attcagtcca aaaatggcta aatttgccca atctgctttt gaaaagagct ggatcgaagc
    21001 agaagatcgt cctgggaaac gtcctggtgg ttattgtact gagttaccag aaacaaaaga
    21061 atcaaggatc tttatgacct acagtaattc tgttaatgag gttgcgacac ttgctcatga
    21121 actaggacat gctttccata gcagcacgat gtgggattta ccttctttaa atcgcgaata
    21181 tgccatgaat gtcgcagaaa cagcaagtac attcgcagaa ttgatcgtag ccgatgctac
    21241 attaaaagtc gcaaaaacaa aagaagaaaa aatcaatttg ctagatacaa aactgcaaaa
    21301 tgctttagct atgttcatga atatccattc ccgattcatt tttgaaaatc gattctatga
    21361 agcacggcaa gaaggattag tctcagaaga taagatcaca gagatgatgg ttgaggcgca
    21421 aaaagaaggc tatcaaggag ctttagctac ttaccatcca tatttctggg ctgcaaaatt
    21481 gcatttcttt attgatgacg taccgtttta taacttccca tacacatttg gctacctctt
    21541 tagtttgggc atctatgctt acgccaacca aaagggagca aattttgaag aagaatatat
    21601 ccatttacta cgcgatactg cctcaatgac gacggaagat cttgcgaaga aacatttgaa
    21661 tgtcgatctt acccaaccag atttttggca agcaggtatc gacatggtga ctgaagatat
    21721 ccaaacgttc atggaattga cagaagaatt tatctgattt ctattttatc acaataaaaa
    21781 aagagttagt ccagaatggg ctaactcttt ttg
//
LOCUS       DAFLVO010000050        21560 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.050, whole genome shotgun sequence.
ACCESSION   DAFLVO010000050 DAFLVO010000000
VERSION     DAFLVO010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21560
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.050"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            242..943
                     /locus_tag="L1U99_001917"
     CDS             242..943
                     /locus_tag="L1U99_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBN1212453.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(1552..2568)
                     /gene="tsaD"
                     /locus_tag="L1U99_001918"
     CDS             complement(1552..2568)
                     /gene="tsaD"
                     /locus_tag="L1U99_001918"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBN1212454.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(2565..3029)
                     /gene="rimI"
                     /locus_tag="L1U99_001919"
     CDS             complement(2565..3029)
                     /gene="rimI"
                     /locus_tag="L1U99_001919"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBN1212455.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(3036..3578)
                     /gene="rimI"
                     /locus_tag="L1U99_001920"
     CDS             complement(3036..3578)
                     /gene="rimI"
                     /locus_tag="L1U99_001920"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBN1212456.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(3562..4284)
                     /gene="tsaB"
                     /locus_tag="L1U99_001921"
     CDS             complement(3562..4284)
                     /gene="tsaB"
                     /locus_tag="L1U99_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBN1212457.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(4475..5455)
                     /locus_tag="L1U99_001922"
     CDS             complement(4475..5455)
                     /locus_tag="L1U99_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1212458.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(5479..6963)
                     /gene="galT"
                     /locus_tag="L1U99_001923"
     CDS             complement(5479..6963)
                     /gene="galT"
                     /locus_tag="L1U99_001923"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HBN1212459.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(6975..7964)
                     /gene="galE"
                     /locus_tag="L1U99_001924"
     CDS             complement(6975..7964)
                     /gene="galE"
                     /locus_tag="L1U99_001924"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBN1212460.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            8212..8379
                     /locus_tag="L1U99_001925"
     CDS             8212..8379
                     /locus_tag="L1U99_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HBN1212461.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(8441..10252)
                     /locus_tag="L1U99_001926"
     CDS             complement(8441..10252)
                     /locus_tag="L1U99_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HBN1212462.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(10249..10614)
                     /locus_tag="L1U99_001927"
     CDS             complement(10249..10614)
                     /locus_tag="L1U99_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HBN1212463.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(10777..11172)
                     /locus_tag="L1U99_001928"
     CDS             complement(10777..11172)
                     /locus_tag="L1U99_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBN1212464.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(11190..12152)
                     /locus_tag="L1U99_001929"
     CDS             complement(11190..12152)
                     /locus_tag="L1U99_001929"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HBN1212465.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(12152..12364)
                     /locus_tag="L1U99_001930"
     CDS             complement(12152..12364)
                     /locus_tag="L1U99_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HBN1212466.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(12385..13083)
                     /locus_tag="L1U99_001931"
     CDS             complement(12385..13083)
                     /locus_tag="L1U99_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBN1212467.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(13103..13645)
                     /locus_tag="L1U99_001932"
     CDS             complement(13103..13645)
                     /locus_tag="L1U99_001932"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBN1212468.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(13777..14781)
                     /locus_tag="L1U99_001933"
     CDS             complement(13777..14781)
                     /locus_tag="L1U99_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBN1212469.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(14778..15767)
                     /locus_tag="L1U99_001934"
     CDS             complement(14778..15767)
                     /locus_tag="L1U99_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBN1212470.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(15764..16570)
                     /locus_tag="L1U99_001935"
     CDS             complement(15764..16570)
                     /locus_tag="L1U99_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1212471.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            16736..17692
                     /locus_tag="L1U99_001936"
     CDS             16736..17692
                     /locus_tag="L1U99_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1212472.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(17769..18287)
                     /locus_tag="L1U99_001937"
     CDS             complement(17769..18287)
                     /locus_tag="L1U99_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBN1212473.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(18375..18524)
                     /gene="rpmG"
                     /locus_tag="L1U99_001938"
     CDS             complement(18375..18524)
                     /gene="rpmG"
                     /locus_tag="L1U99_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBN1212474.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            18752..19198
                     /locus_tag="L1U99_001939"
     CDS             18752..19198
                     /locus_tag="L1U99_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBN1212475.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(19393..21288)
                     /gene="asnB"
                     /locus_tag="L1U99_001940"
     CDS             complement(19393..21288)
                     /gene="asnB"
                     /locus_tag="L1U99_001940"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBN1212476.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT         6495 a         4563 c         3708 g         6794 t
ORIGIN      
        1 attaaaaaaa taaattatat tatcgttgtt agcgtttact atatgtatta ttgttgtttt
       61 ttatacacaa atcattcgct tcaaaacaaa ttattcaata ccattgtata ttttttacat
      121 aataacaaat tatatttgta aagtattaaa acttgtttct aatgttggta tgttaaaact
      181 ttacaaattc tttaaaaaaa gtgacaataa atatagtgaa caataaggag aggacttttt
      241 aatgcgtgtt aataaaatcg attttcactt ttcaaaactc agatatcaac ctgattttga
      301 acatttctcg gatgaagagt tccaacagat caaggaacat actgttcttc gttcttataa
      361 aaaaggacag atccttttcg acgatggtga tcccagacaa cggttgtata tcttgaccaa
      421 aggactcgtt cgtttagaac gttatgatga aagtgcaact tattactact atgactatgt
      481 gaatacaaat aacctttttc ctatgtcagg aatgtttgga gaagagacct acacttatac
      541 agctcaagcg atgactgata ttgaaacatt ctaccttcct gtttcctact atgaaaaatt
      601 agcacgaaaa aatcccgaac agttgatcta tatgatacaa aaaatttcta aagtagttga
      661 aatacatgaa ttgcgtatcc aaatcggatt gacctctagc gcctttgacc gggtaaaaca
      721 aaatttattc attttgaaag aagaattggg cgtaccaaca aaagatggtc atatcaccat
      781 tccttatccg atcaccttaa aagaattagc agtgaatagc ggcacgacac gtgaaactgc
      841 tggacaagta atcaaacaac tacgtgattc cgggctgtta gattatgaca aaaagcgttt
      901 tactttctgt aagacagcta ctactccagc tatgagagaa taacgcgaac aaaaataagc
      961 agtgaccctg ataaatatca gggtcactgc ttattttcct ccctaaaact tctgaaagat
     1021 ccggcagttt tagatcactg gacaagactc aaagattttc tatgtgtgtt tcagttatgt
     1081 aatattcact gtttgcaaaa aatactgtta gattaactag atgaagcgtc ttgtcctcat
     1141 ccgatctaga ttattcgata ttcctcgaca ataaacgatt actcagtgag ggcaatcaga
     1201 ggaacggata atgataaata agctgtaaaa aatagcaaaa taacaataat gattaaaagt
     1261 atgtaaaaaa tagggctttg acaaaaacgt gtcacagccc tatttcgatt aaacggtgtg
     1321 tacctgtcaa ctcttcggtc acaagtcata atgttcataa acatgaggag ctgttttttg
     1381 aaattgttcc ttgtgaatca gagttaaacg acaggcttac gaactcttga ttaaacggcg
     1441 ttcaaaagct tgcatacgcg gtaataagaa cagccaggtc aaaaacatga gaagccgttt
     1501 ttcctgggct gttcttatta cttgatgcag ggcagctttt tcacaacctc tttattcaga
     1561 taaaaccaag cttggatcag cattcaactg atagctagca aaatttcttt tttgcatttc
     1621 cacatgtgct gctgctccaa tcattgcagc attatctcca caaagtcgaa gagggggaat
     1681 cactagttct acctcaggga gtttagctgc caaagcatcc tgcaatcctt cacgcaaccc
     1741 ttgattggcc gctacacctc cagctataat cagttgcttg actggataat tttgacaagc
     1801 tcgaagtgtt ttagtaatca atacatcgat cacacttgct tgaaagctag ctgctaaatc
     1861 atttttgtct agatcttctc cacgctgttg tgcattatgc accaaattga taaatgcact
     1921 ttttaatccg ctaaaactga aatcataatt atcttcatgg atcatcgctc gcggaaaatg
     1981 gtaattatct tttccctgat gagctagctg atcgatttct tttccgcttg ggtaagaaag
     2041 acctaatact cttccaactt tgtcataagc ttctcctgct gcgtcatctc ttgtctcccc
     2101 aatgatttca tatgatccat cttcttgcat atagactaat tctgtatgtc ctccgctaac
     2161 aagaagtgcc atcaatggaa actggaatgg tttaaccaga cgggctgcat agatatgccc
     2221 tgccatatgg tttacaggaa taagcggcaa ttggtgtgcc caagcaaaag ccttagctgc
     2281 agaaatacca atcagcaacg agccgacaag tcctggtcca taagtgacag cgactgccga
     2341 taaatcttct gccgacacac cagcttctac cagtgcatct tccaagcata aggtgatttg
     2401 ttctacgtga tggcggctag ctacttcagg tactacgcca ccaaaacgtt tatgactgtt
     2461 tatttgagaa gcaacgatgt tagataagat ctctgttcca tttctaacga ccgctacact
     2521 cgtttcatca caacttgatt caatcgccag aatcaattct tcattcattt catcgtctcc
     2581 gtttttaact ttctgctcat aatgatcgca tcttccgtcg gattgcgata atatgatttc
     2641 cgtttaccta atatacgaaa cttttctgat tcataaagtt ttcttgctgc ttcattagat
     2701 agacgtactt ctaaaaaaac atgcagcgaa tcttttattt gttccgtaat cagtaattgt
     2761 aacaaatgcc gtgcatgccc ttttccttgt tctgaaactg caacagcaat atttgtgatc
     2821 tcgacttcat ctattacttt cgagtatcca ataaagccac agatctggtt atcttcagct
     2881 aaaagcagat aatcagagtg aggctgttgg atgtctgcca aaaactgcat tttcgtccaa
     2941 ggtgaaccat gtggataagc attttcgcta atcatccata cgcattctgc caagtacgct
     3001 tcatcaaaat ctttttttct gcaaatcaac taatctcact cattttctaa aagttttatc
     3061 atatccaacg catcttcttt tgtttcagtg taatatcttt ttttgatcgt tgttgcttga
     3121 aaccccaatt tccgataaag tctttgtgca tcttgattac tcatacgcac ttctaatgac
     3181 atcgtctcac agcgattcat tatagcaaag ttctcgattt cgtcaataag cagcgaaccg
     3241 attcgtttac gctgatatgc cggtcgaacg gcaatattcg tgatatggca atctaaaccg
     3301 aacgctcttg aaccgataaa accaatcatt cttccattat caaagatacc tagatataga
     3361 tgaggaagcg gtgacttcaa ttctgatata aaggcacttt ttgtccatgg caattcgcca
     3421 ttatagactt ctcgttcgac atccagcagc tctttgatat cttctgtagt caattctctt
     3481 agtacgtaac gacgatcgat ttgttcgact gttttttctg tataaatcat tttatcttga
     3541 aaaaagcttc tggcatacgc tctaaatttt ttcaacataa ctttcgtctc caggtgtgtg
     3601 cgtctccaac catttttctt ctgcttctac tcgttttaaa tagcgaggaa gaaaagcttg
     3661 tttctctgca actggttcaa ctaaagcacc taattgagcc acagttacac cacttggaat
     3721 atcccatgct ggaactgtat taatcatcgc actaggcaat atttccttta tttcagagaa
     3781 gaatttgtga caatcactcc cgacgaaata aatagcttca ttcagctttt gtagttgtgt
     3841 gaacaaatca gaagcagaaa tatgtacatc ttcaagtaca gtttctaatc tattttcttt
     3901 ccagcggtat gccccagcgt atacattttt tcttcgagca tcaaacatgg gcacaataat
     3961 attatccaca ccgatgcaat tagccgcgat ggttttcaga ctagatactc ctactagctc
     4021 tttatctaat gtataagcaa tcgtttttgc tgtcgttaca cctatacgaa gccctgtata
     4081 agaaccggga ccatcagaaa ccgcgattcg gtcaatgtct tttggactta tttgaagatc
     4141 tgcaaacaat tggtcgattg caggcatcag tgttacactg tggttgcgtt tgatatttgt
     4201 ttgtatttgt ccaagaattt gttcgtcttc taccacaccg atcgccaaag tttggtttgc
     4261 agtatctatt cctaatgtaa tcatatattt gatcctttct gctatgacat tctcgccttc
     4321 cattgtagca tactttttta ttctgaggat gaaaatacca aaggcaaaac tagtacaata
     4381 atacatgatt atctgctggc gggcaaattt tgccccttcc tgaaacacaa aaaagctgcg
     4441 gtatcactcc attttcccac agcttttcca tcttttattt cgttgattct cgaataatca
     4501 actctgtttc cacaataatc tttcttgaaa ccggtgcttt ggaattactt aattgaagaa
     4561 tcgtctccac tgctagctct cccatccatt cggtataaac ttttacagta gaaagcgagg
     4621 gcgttacata tttcgctaca ctgacatcat tgaagcccat cacagaaata tcttctggta
     4681 ccactaaacc tttttcttga atcgctttca gtgcgccaat cgctaatgca tcattagctg
     4741 caaaaagcgc atcaggaaca tgcggattcg tttttaaata ttgcttcact gcttgatatc
     4801 ctgactcgac agaaaaatct gcttcgataa ttggaccttc gtcgtagcct ttttctgcca
     4861 aaacttgttg aaatgccata attctgggat cttttagccg ctgatggttt ttcttcgtat
     4921 attctgttcc agcaagcata gcgatatgtt gcgctttatg ggagacaaag tgttcaatga
     4981 ctttttgaac acttgactta aagtcgacaa ctagagagtc gattccttga gaagtgccgt
     5041 cagaatctac caaaagcaag gcattttggg atcctttcat ttctaataac tgagcttcgt
     5101 cgaattttcc tagtgcgatc gttccatctg ccggaagatc actaatggaa tcccacgttt
     5161 ctttcaataa agtaacgttt gcttcttctg cctttttttc gattcctagg cgaatagata
     5221 aataataaag atcttcaagc tcttccgtat cgtcgtacca ctggatcagg cgaagcgttt
     5281 gcttagtatt tgctgcattt ttacgatgtt tcgtataatt taagcgttct gctgcttcaa
     5341 aaattttttg ctttgtggct aagccaacgg aaagatcagg atcatagttg agaactcttg
     5401 aaacagtagc aggagaaact cctgccaact gcgcaatgtc tttaattgtt gccatttgtc
     5461 tctcctcctt ttttacgttt ataaaatcgc agtaaatcgt tcaaacgctg cctgtccttt
     5521 ttcatctcgc ttgaatactc cagcgtcttc cagtacacgt gcaaaaacct gacctacaga
     5581 tttttgtacg acatcggtga ccgtatcttt cgtcaaatca ggatgttctt tttttaattg
     5641 ttctgcccac ggacgatgat attcagccat ctggttttct tctcctaata agaaatgctc
     5701 tacttctact agttctggtt tcaaacgagg tggtaaaaca gcaagcccca ttacttcgat
     5761 caacccaatg ttctcctttt tgatatgttg gacatcttta tgtggatgaa aaatcccatc
     5821 aggatgttct tctgaaacat tgttgtctcg aaggacaagg tccaactcaa agtaattgtc
     5881 ccttcttcgt gcaattggcg taatcgtatg gtgtggtgta ccatctgctg aaaaagctct
     5941 gatagatact gtttcatccg aatatgcttt ccatttttcc aatactgagt tagctgcttc
     6001 aataagcaag tttttctctg ttgattgcaa acggatcaca gacatcggcc atttcacgac
     6061 tcctgcgatg acttgcggat aatcttctag tttgataagt ttttctatcg gtgcttttgc
     6121 cataggaaat tcatgacgtc ctgcctgata atgatcatga gaaagaatcg atcctccaac
     6181 aattggtaag tcagcattcg aaccaacaaa gtaatgaggc aagacttcag taatccgaag
     6241 cagtctagca aatgtttcct ttgtgatttt catcgggcgg tgttgttctg ataaaatgat
     6301 cgaatgttca ttgtaataag cataagggga atattggaat ccccagcttt caccgtctag
     6361 attcattcga ataatccggt gattggtgcg ggctggatag ttcaagcgac ctctatatcc
     6421 ttcgttttcc atgcaaagca tgcaggtagg atagtctact tttaccgcct cgcgttctgc
     6481 tgcgatttgt tttggatctt tttctggctt agataaattg attgtgattt ccagttcacc
     6541 atactccgac tctgccggaa atttgatgtt ttttgcgatg gctcttgttt tgatgtagtc
     6601 atttttctta cttaaattaa agaaatactc agttgcttcc tctgggcttt tcgaatagtg
     6661 ctgtgcaaag aatgcattga cgactgaagg tggcggtgtg agaaaatcca ttaattgcgc
     6721 ttcaaaaatc tcttgttctg ctggcaattc tgaaagaaca ccattttctc ttgccttagc
     6781 gacaagctga tccaataagt ctacagattc ttccttaact ggtcttactt caatgctttc
     6841 tagagcatct tctcctacca tccctaaaag acgattctgt aaatataagc ggtccatttc
     6901 catccatccg ccagcttcga tcgcaagtgt ggcaaaatca caaatcgttt gactgattga
     6961 catatctcat tcccctattc ttcataacca tttggatggc tgacatgcca atcccatgct
     7021 gttttgataa tcgctttgat atctgtgtat tcaggtttcc agcccagaat ctctctcgct
     7081 ttttcacttg aagcgactaa tcggctagga tctccagctc ttcttggtgc tatttctgct
     7141 ggaatttctt ttcctgtcac ttctctagct gcttctagca tttccttgac tgagtatcct
     7201 ttgctgctgc ctaaattgaa gaagttgctt tcatttcctt ctttcaagta ttccaaagct
     7261 aaaatatgtg cagcaatcaa atcttctact tgaacataat ctctgataca tgttccatct
     7321 ggtgtatcat aatcgtctcc ataaacagcc aaggcttttc tttgaccaag agctacttgt
     7381 aaaatgattg ggacaagatg cgtttctggt gtatgatctt ctccgataga tgcatctgct
     7441 tttgctccgg ctacattgaa gtagcgcaaa gcgacatagc gcatgccata tgcttggtca
     7501 caccacttca tcattttttc catcatcaat ttactttcac catacggatt tttaggatta
     7561 gctggtgtat cttctgtgat tggagactct ttcggctctc cataagttgc tgcagtagaa
     7621 gagaatacga ttttattcac gttgaactcg tgcatgactt caagtaagat ttgcataccg
     7681 tatacgttgt tgttgaaata catcaatggt ttttcgacag attctcctac taaagagctt
     7741 gcagcaaaat ggattactcc ttcaatcggt tccttttcaa atacggaacg tagaaattct
     7801 ttatcccgga tgtctccttc ataaaaatga gcatctggat gtactgcttg tttgtgacct
     7861 gtgagcaaat tatctaccac agctacttga tacccctttt gaactagctg gtctacagcg
     7921 tgcgaaccga tataaccggc tccgcctagt actaaaattg tcataaaaaa cactcctttg
     7981 attagtaaaa ttgtgtttgt tgattctata taatttaaaa aacgaagttt acttttatgg
     8041 tgaaaacaaa caaagtaaaa tttcgtaaat tcatatggta aatttataat aaaacattta
     8101 gtaaacattt tcaagggttt tttgcaaagg tttacaaaca aacgtaaaac tagccttttt
     8161 ttctcttttg ttccataata gatataacaa ataataaatg aggtggattc aatgaaaaaa
     8221 tttgtatctg gaatattagt aggaagtctg gcaacagccg ctgccgttgc tggtttggtt
     8281 gcttctgtga aaaaaacagt gatcgatcca attgacgaaa aagaagcaat gatcgaagaa
     8341 aaccgtaaaa aagcaatgcg taaacgcgtt tctcgttaat aattatttaa aaatacgcat
     8401 gaagactttc taaaaaacag ataagtcatc atgcgtattt ttatttgtca gtcaatataa
     8461 gttgtgctat tttatctgcc tgtctcagat tccatggatc tgtataaggt ctagctactg
     8521 ctgcagttag ccaatccaca ccttcaacag gtattccata gcaataaaag tcagactgga
     8581 tttcccctga agcatcaatc acgcgattcg tacctcgctc aacatctata gcttctgaat
     8641 gataacttcc tgtattatct gaaaatgaaa aagggcgaac aagtttgttt tccttcaaat
     8701 tttttatgac aggattactt gaacgagaaa agcttgtttg tggcaatcga gcttcaatca
     8761 aatagcgact gctgatttct ttatcttgta gagaaataac atagcggttg tgcttttgct
     8821 gaatatcaaa tggcggttcg atcaaatgaa aaatacccgc atctatcagt gctgctaatt
     8881 ctttcgtccg aatgattggc ggaccgatcg ttaaaaagct atttagatga gtaaaccatc
     8941 cccatagtat ttctttgtat tccttagcag aaaaaacgtg ccattcaata gcctgccgga
     9001 ttggatcacg ccagtctttt aatgcatcaa atgttgaagc aaatgctcct gtgcaattgc
     9061 ctttttccgc ttcttttatc tgcccttcaa taaatattcg gctagcttct gaaaagggct
     9121 cattctgata ggcaagagga gtttctaaat acgaccaatc ccatctataa gggattagtg
     9181 ctggatgctt tccgagacac tcctctgaag agagggagag aaaatcatgc tcaaaatttt
     9241 tctttggaat cggcaagtga tattcttcga tgattttctt gtaataaaac aactcaacgt
     9301 cttttttcag atagtcaaaa aatgtttcgc cagtcaaaaa tcccgactga tgccattgct
     9361 ccaggttttc ttttgttagt aaccgtggcc atgccattgc tccgccttgc ttttgatttc
     9421 ttcctcgagg gtaataaggg agcccccttc ttgatccact gtatacaatc ggttccttgc
     9481 ctgatggatg atagaccagt tttccctttt cgttctcgaa gcgccctcct cttgatactg
     9541 taaacaatcc gacataatca aaaaaactta agcctagacc tcttaaaaag acattttctt
     9601 taggcggtat cttcgaaaga tctacatctg caggattaga aggaagctga tacagtaaaa
     9661 catttttctt tgcgtagtct acccacactc tttcttcttc tgtctcatca ttttcccagt
     9721 gaccgcttgc taaaacaagc tgatcgatag aatagctttg ctgatctgtc tgtaaaagat
     9781 aaccatcttt tcttttgctt acttttttta ctaaagaata aacaaactga atagaagctg
     9841 gaaattcttc ttgcaacttt gagaaaaacc agcgttgata gagtccgtat aaacatcgag
     9901 tagattgctg atctttttcc agacgattga tttcttctat aattagttgc ttatttttgg
     9961 ttaccgtctg ttcgatataa tctgtagcag gtcctttact ccattgaaac aagttgggtc
    10021 cctgtgttac caatcctcca ctggacaatg tttcatctgt aaaaagcgtc acttgttgag
    10081 aaacagaatt cattaataac tccggtggct gattcaaccg ccaaactcga cctccaggac
    10141 cattgggatc gaaaagaaaa agttcaagag aatgtctgtc ctgattatta tggagaatcc
    10201 tttctgctac acttaatcct ctaggtccgg caccaatgat ccctattttc atttgcatgc
    10261 ctccatttcg ataaattttt tcaataaaac agcatggttc tgatgttcat tttttgcacc
    10321 ataaacaaaa gtaatgactg gatgttcttt cataagttga ctgagtttaa aaatagcttg
    10381 cttcttttct tcttcgaaaa tcaattcttg ctggtatttc tttgcaaatg aagcaaatcg
    10441 ttctggtaca tggtcaaaag ttttgcgtgc ttcattacta ggtgcaattt ctttcaacca
    10501 cagatctaac tgcgcttttt cttttgaaat tcctcgtggc cagaatctat ccacgagtat
    10561 tctatagcca tcctcttttt cagcatcaag gtaaacacgt tttaatttga tcatagttgt
    10621 ttccttcttt ctaccttttc gcttagctta tatatgtaga taatagcaca aaataaaaaa
    10681 aatgaacggc acaactatcc attgcgccgt tcatgtgatc ttggtcaaaa tctaatgatt
    10741 gattcggttt ttaaagctgt catacaatca tctgttttat acttttttac ttttgatttt
    10801 tccagaccat ccgtcatatc cacccttaag taaataaatc tcttgataac ctgctttacg
    10861 taatttattt gctgtacgga tgctcaaact tttcttttga tcgtaaatat agacaggctg
    10921 gtcttttcga atagatccta atgaatcttt caaaacagtg taagggatgt ttcttgcacc
    10981 taaaatatgc ccagcatcaa acacatcttt ttcgcgaaca tcgattactt gtgcttttct
    11041 cattccttct cgaaattctt cttctgtcaa agtcgttgct gaacgtttgg ccattactcg
    11101 tagatagact tcccaaagga tgattgcaag cacaatcaat agcaaaatga tattaattac
    11161 ccataaaacc atgtaatgcc tccgtttttt taagcaaatt tcaaggctaa tgaggcagca
    11221 ccaatgacac cagcttcatt accaagctct gctaatttga tttttgttga ttctcttact
    11281 tgcgggaaag taaattcttt aaaatatttc tctacacggc tacgtaaaaa ttctcctgct
    11341 gccgatactc ctccacctaa cacgatactt gacggattta atgtattccc caagtttccg
    11401 caagctaaac ctaagtagaa gcatacgcga tcaacaacca tcaatgcaaa cggatcgtct
    11461 tcttgagcca tttcaaagat atctttactt gttacttctt ctccgttgtc tagcattgct
    11521 ttcagttttg aatcccctgc gtattcttct gccaagaaac gacctaggcg taccacacct
    11581 gtagcgctag atacagtttc taaacatccg cgtttaccgc aagtacattc gaacccttca
    11641 ggatccacag tgatatgtcc gatttctcct ccagctccgc tcacgccgtg aatcaaattt
    11701 ccgccagcaa cgatacctcc gccaacacct gttcctagag taacgaatac aacgtctgga
    11761 tcgttttctc cagcaccttt ccatcgttca cctaaagcag caacattcgc gtcattatcg
    11821 atagcgaatt tgattcctgt tcctgcctcg atcagttttt tcacaaattg aacttctgtc
    11881 cagtttaagt tatacgcacc aataaccgtt ccagcttcgc tgtccacgct tcctggggta
    11941 cccatgccga ttccgataaa gtcttcggct ttcatattat ataaattcaa acgatgattg
    12001 attgattcaa tgatttcagg aacgatatgc ttaccatcat ccaaaatatt ggtatcgatg
    12061 ctccattttt gctgaatctc tccttctggt gttaaaattg caaattttgc tgttgttcca
    12121 cctaaatcaa tcccaataat cttcttgtcc attacaaatt tcctttcttt cggctttctt
    12181 caattcggtg ctctcttttt aatatgcgcc acgctgtcat gtatgtatca tgatcaatca
    12241 aacggctatc atacagatta cgcaattcga tagtcattaa ttcaatgtca tagatgcgtg
    12301 cacccacata gataaagatg ccaaattttt tgaacagctg ctgtacatca tataagctct
    12361 ccatctttaa gcacttcctt catattatac aagtaaacca tattttttta aacccagtaa
    12421 aatacatatt acaaaaagaa atacaaaaac tagtgtagaa agaatccttt ggtgtatcga
    12481 atagcttgtc tgttgtttcg gtagacccaa aacattccct aacactaatc cgccaattag
    12541 cccaccgaca tgtccccaaa catctacaga ggtatccaga agaccaaaaa caaatgtcaa
    12601 cacaataaat aaaagaaaat gtctgactag ctgctggatc gctgggttat gtttaaaatg
    12661 aaaccctaag ataaacaacg caccgaacaa accgaatatc gaagtacttg caccaccaga
    12721 cagaacattc gcttcgttaa aagcaaagct tgctgtattt cccattatcc cgctgaacat
    12781 ataaatcaag aaaaaacgcc aatggccata gattgcctcg atttgctgcc ccataaaata
    12841 cagtatcagt gagttcatta cgaaatgcat cagtccaaaa tggatgaaga ttggtgtcac
    12901 taaacgccac cattcattga agtgaacaag ataaggacca tacattccgg cataataagg
    12961 gatctcaagt cgcggaaata attccatcat gaggaagacc gctgtctgta tccctaaaaa
    13021 agcataggtc cataacggtc gtcttaacca tgcacgcaat tttatttgct gttgataatt
    13081 catgaaaacc tcccatttca ttttagtcaa taaacaattg ttggatcttc tgatcaaagc
    13141 tctccggttg ccattgttca ttcaattgtt cacgaaaaac aaggctacat gtttttttat
    13201 gaaaattatt taaataccgg tcgtaataac caccgccaaa accgattcga taaccggctc
    13261 tattgtagat aatacctggt acaatgagga gatcgatcat ctccggcaaa tagagcttct
    13321 ctgattgtgg ctcaagaaca ccaaaactcg aacgtacaag aacggactgt tcatccattt
    13381 cataaaacgc catctgacgt ttcggcaaag ttttaggtac aactattttc ttttgttctt
    13441 tttctgctcg ttggataacc ggctgtgtat ccagttcaaa ttcattcgat aaagtcgtcc
    13501 ctatcacttt tgctgacttc cagtactcgc tggcgaatag ctgtttatag attcgctgtt
    13561 ctttttcctt tttcttgcca cttttggcca gatttttcag cttttcgatt cctttccggc
    13621 gtaatcttac tttcaattgg tccaaaaact cacccttcct tctctcataa aatggtatag
    13681 gaaaaaaaga aaaatagcaa tcgaactttc aaataaatgc ataaatagaa taaaaagaag
    13741 acctagaaat gattggcctt ccttttttaa tgaatttcaa ctgttcagcg cgtgtttttg
    13801 tctgataaaa agtgcataca gaaaatatgg cgcaccaaaa agggcaatca aaattcctgt
    13861 aggtacttcc ccacttggta gaatcactct agcaaccata tctgcactaa gcagaaaaat
    13921 ggaaccgaac aaaccgctca gaacaaaggt ccagttattt tctttacgta cgactagctt
    13981 cgcagcatga ggagctagta gtcctacaaa agataaacta cctgtcaccg ctacactacc
    14041 gcttgccaaa gcaacagcta acaacaaaag gattttttga cttttagcca cgttaaggcc
    14101 taatccttgc gcgcgttctt gaccaaatga tagcaataca atcctctgtg cataaagtcc
    14161 tcctagcgga attaagataa ccgcccatgg aagcaatgcc caaacataag gccagctcgc
    14221 accccagatt gatcccgcta accatgcatt cacaaatcca taattttcct tagataattg
    14281 gatcgtgcat agcaatgtta atgcagaaag gccggcatta acggcaatac cggacaataa
    14341 gattcgattc atacccaaaa agccatttcg atcataggcc gcaagataga cacagcaagc
    14401 agctaaaaca ccacctagaa aggctacaac tagcaataga aacggcagcg aatagtgcga
    14461 aaagaaacct aaataaagca tcactaaaaa tcctgctccg gcattaatgc ccaatatact
    14521 agaatctgcc aattcatttc ttgttactcc ttgcaagata taaccagaaa cgccaagaca
    14581 agctcctgct aataaactga tcagtaatcg aggaactcga aattctctaa caatcagcgc
    14641 caaagaagat gattctttcc ctatgaacgt ggcaaaaagc tgatccaggt aaataaaagg
    14701 cgtaccaatc attaaactac ctatagacag gatgacaagt acaaaaagca agaaatagaa
    14761 cgtccaatat atttttttca ccgttgttcc ctccttactt gtatcagtaa aaacggaacg
    14821 ccaatcaatg caatgactaa tccaaaaggt gtttcaaaag ggggattgat catcctcgct
    14881 gtaaaatccg ccaacataac caatccaccg ccaactaaaa aagagacagg tagaacataa
    14941 cgatagtccg ttccaaccat tccgcgaaca actggcggaa ccaacagccc aataaatgaa
    15001 acaggtccga ctaacgaaac ggcaatggct gctaacactg caactagaca gaaaacaatc
    15061 aaccgcgttc gtttaggatg acttccaaga gctaatgcat gtgtttcact caaatgaatc
    15121 aaagatattg cttttcctaa tgaaaaagaa accaaaacag caagtatata taaaggaaac
    15181 aatactgcta attgtttcca tgtgatattg gcagctccgc ctacaaacca aaaagcaaga
    15241 tcctgctgca gattaaagaa ttgggtaagt gcttggctga tagcagtaaa aaaagaacta
    15301 atagctacgc cagctaaaat cagctgtaaa ggattcatgc ccattttcga aaactgcaaa
    15361 aaaccaaata cgagcaaagt tacagcaaaa gaacctgcca atgacattag aaacacagaa
    15421 aaatcagaag ctttaggcca aaaagcaaaa ctaagggcca ttgccaacga agcacccgcg
    15481 ttgattccta gtaagcctga atctgctaaa ggatttcttg tcactccttg catcaatgca
    15541 ccgctcaatg caaaacaact ccctacaaga aatgctcccg ccacacgagg caaacgaata
    15601 tttcgtatga tttggtgact ttgttttgat ctatcaaaat caaacaacgc ctgccaaaaa
    15661 tctgcttttt ccacagtcgc tgcgccattt gaaagagcaa caaaaaaaat aatcaaaaga
    15721 acaaaacaga ccaaaagcag gagtctattt ttcttcatag tcctcataat tgatcctcct
    15781 gctcttttgg caacaaatca taggttagaa aaactggttt atttgttctt ggaagcgtga
    15841 caatcgttgc atcaatctca aatatttttt tcatacactc ttttgtgatc acttcttcag
    15901 gtgtaccttc tgtgatcaac ttaccgtttt tcattgctaa taaataatct gaaaaacgtg
    15961 aagcatgatt aatgtcatga atcgacatca agatcgttgt ttgtttcatt tgattgattt
    16021 cagtcaataa ctgtaggatc tctaattggt gtgccggatc taaaaatgtt gtcggttcat
    16081 ccaagatcaa gatatctgtt tcctgagcaa gcgccatagc gatccagaca cgctgggttt
    16141 gtccaccaga cagcgttgcg atatcccgca tacgaaatcc agctagacct gtagcatcca
    16201 acgcccactc aattgcttca tgatcttgcg tgtccatgcc actgaacagt ttttgataag
    16261 ggtatcgtcc gtaagatact acttcttcta ctgtcatacc tgtagggtgt tcactagttt
    16321 gtgctaataa tgcaattttt tttgcaagtt cttttgaact gtatgtagag atatcagagt
    16381 tattgacaat gatctttcct gatttcacag gtagtatacg ggtaaaactt ttcaataaag
    16441 tagattttcc acttccattt ggcccaatca aactagtgat tttcccttca ggaatcgtaa
    16501 cagacatgtt ttcaatgatt tttttgtttt cgtagccggc tgcaatgtca gctgctctta
    16561 atctcgtcat ttcacccatc ctttcgctga aaatcattct caattatgac gctgtttcaa
    16621 catttcgtca agcgctactt tcatatctat agccaaatga agcggttgac agcgttcgaa
    16681 atatcaggaa taataaccaa tgagaaagat tctcaattat gttaggagga aagaaatgaa
    16741 attaaaaaca aaagtattca cattatctag catattgctg ctggctggag tactgagcgc
    16801 ttgctccccc tcttcagata aagaaacagc tacaactgcc aattcgacga cttcatccaa
    16861 tagtactcat acagtcacag atacacttgg acataaagta gagattccaa acgcgcccaa
    16921 acggatcatc ggcagttact tagaagacta tctgattgca ctaggggaaa aacctatcgc
    16981 ccagtggact gttggcagtg gttccattca agattatctg caagatgatt taaaggatgt
    17041 cccaacgatt tcttatgacc ttccttatga gaaagtgtta agctttgagc ctgatttgct
    17101 gttgatttct tcttccgcta ctgtcgaagg cgggaaatac gaacaatata gcaaaatcgc
    17161 gccaacttat gttgtaaaaa acggaacaga tgtcacatgg gaagaacaac taaaagatgt
    17221 cggcaaagct ttggcaaaag aaaaagaggc agaaaaaatc atttccgatt atcaaaaatc
    17281 catcaagaaa actcgagaag aactagcaga taaaatcgag aacaagacag ctgcagtgtt
    17341 gtgggtgacc aacaactcag cctttatggt cagcaaaaat cggtcaagtg gaagaatcgt
    17401 atacgacgat ctggaatttg gtgttcctga tctagtggaa gaggtctcca aaaaagccac
    17461 ttctgactgg tctgctgttt cctctgaaaa gctagctgaa ttagatgctg actacatcat
    17521 ccttgtgaac agtgacaaag atgctgccat gttcaatgaa ccaagctgga agaatctaaa
    17581 agcagtgaca gacaatcatg tactgcaatt cggacctgaa tctagttggc tatataacgg
    17641 acctattgcc agtcaggaaa tggtcaatga tatcaaagaa aaactaaatt gattttaact
    17701 aaaaaaagca tcttcacgat tagtcgtgag atgctttttt tcttattaac aaactagacg
    17761 catagatttt attcttcttt tgaagcaacc ctatttttta ctctttccca tttttgaaaa
    17821 cgatgggcat atagattttc ttgatccgtt atcccctcat actcctctat aagggcgaag
    17881 tctgaaaaat caatattccc aatatacgta tcgccttcaa acgtgctatc gatcaatgtt
    17941 cgccagatcc gaccagtgta aggaagaagt tcttgaaaaa tccgactacc acccgaaaca
    18001 tagatatctt ctgagatcgt ttgactatac gacaaaagtt catcgatcga atgcattact
    18061 tccgcatttt ctttcgtgcg aaaatttggt tgcgttgtca acacgatgat atggcgataa
    18121 ggaagtgaaa gatcccccat tccttcatag gtctttcttc ccatcactaa aattcgatcc
    18181 attgtatgtt cgcgaaagaa acgcatatca tttggcaatc gccatggtaa caaaccattt
    18241 ttgccgatca gaccattttt atcttgtgcc cacatggaaa taaacatatt atccgctcct
    18301 tatgatttta gatgttttga gataaaaaaa gtctcaattc tttgaccagc aaggaattga
    18361 gaactttaaa aacattattt tgtttcacgg tgcaaagtaa ctttgcgttc gcgtgggcaa
    18421 tatttttgtt tttccaaacg atcaggattg ttacgtttgt ttttgcttgt tagatagtta
    18481 cgttctttac aagaagtaca ctctaaagtg atgtttacgc gcatgttttt ccctcccatt
    18541 tttacaagaa tcctctaaga tgactctcag acttgattat cttaccatga ttttttctag
    18601 attgctagtg tttttcacga ttttgttaag taaaactact tgacgataaa tacaacggtt
    18661 ttacttctca aacaaaatct ttttcttttt gtataaatac ccttacactt gtttatatag
    18721 attatgtttt ttaataaagg gggatactaa tatgccatgg aacatgaagg actttcctgc
    18781 atcaatgaaa aacttagata aattgacaag aaaaaaagca atcgacatcg caaatgcatt
    18841 attagatgaa gggtaccctg ataaccgtgc gatcccaatt gccattgatc aagcaaaaaa
    18901 atggtatgaa gatgctagtg aatcagaaaa acgaactttc gaaaaagaaa aaaatccaag
    18961 caagacggat gaacacgata cgaatcctcg tgctggaaaa ctgcttgatt cagatgtgat
    19021 cgtagaatat gaggaagaac aatggatcgt gaaatctaaa ggggcaaaaa aggcaagcaa
    19081 ccattttgat acaaaaaaag aagcaatcga aaaaggaaag caagtagcac aaaacaaaga
    19141 atcaactttg ttcatttata aaaaagatgg gacaaaagaa aaagaaatcg attattgaac
    19201 atatgtaaag gggttgtgac gaaaatcgtg tcacaacccc cttatgttcg aaacaatggt
    19261 gttcctctgc caactccgaa ccataagtca taatatctat aaaacgggaa gagctgtttt
    19321 ttgaaattgt ttcttatcac tcagtgttaa acggtaggag aaaacctctt ttttattgat
    19381 atttgatttt catcaaacag tcacatagtc gattgcttct gcttgcggaa tcgtttcatc
    19441 tacaaagtag actttatacc atgtcaagaa actgaagatt gtccagattt ttctttgctc
    19501 ttctttacgt ccttcgtgat ggtcatctag caacttcatg attttttctt gatcaaaaaa
    19561 ttcttttgca aaatctgctt cgaataatgc tttgacttgt tcgtagccgt gttcttcttt
    19621 caaccaagct ttgattggca cagggaatcc taatttcaca cgattcgacc attcttccgg
    19681 aagatgtttg ttcgcagctt gtctgaaaat atcttttgtg ttgttttgat tcaataaaaa
    19741 cttacttggt atttgttgag ccaatttcat gacttcgata tccaataaag gtactcggac
    19801 ttccaaagaa cttgccatag aaagtttatc tgcctttaac aagatatctt ttggcatcca
    19861 ttgatgaaga tcgacatatt gcatcttatt gacttcatct ttgattcctt ctgttttctc
    19921 gtaatgaaca gtcatgattt catccacaga tggtgctgtt tgatattttg gtgttaacac
    19981 ttctgatgct tctgattctt cgaacactcg agcatgaccg ataaaatatt cttttgcagg
    20041 agcaagtgat tcatataaat ggatccgtcc atggaagttt ttcatttttc cgattttacg
    20101 tcctaaatta tagcgtgttc cttttggtaa ttttttcaat ccttgagcaa tcacacggat
    20161 gaattttgaa ttcgtatgga atccatacgt ttggtatccc gcaaacagtt catccgcccc
    20221 ttctccagat tggactaccc gcacactttg tgaagcaaga tttgctaaaa agtacaaagg
    20281 tacgcaagaa ggatttgaat caggttcatc taagtgatac tggatcaaag ggaatgcttt
    20341 gaacgacatg tctccgtcga tcactgctgc tgtattatct aagtccaata gttcggttag
    20401 ttttctggct tcaatcgctt cattataggt tttatcatca aacccgattg agaaagaatg
    20461 atctggtttc aatacagagg ttacataact ggaatcaacc ccgctggata agaaagaacc
    20521 aacttctaca tcactgaccg tatgtgcttc aatagaagct tgaacggttt cgtcgatttt
    20581 ttcgatccat tcttgtcggg aatgcgtttc ttttgtttca aaatctgcat cccaatattg
    20641 ctgaatgtct atttttccat ctttatacgt ataataatgg ccttcaggca aacgatagac
    20701 atctttgaag aatgtttcgc cgtttaatgg agaatattgg aaagtcatat aaggtttcaa
    20761 cgcttctttg ttcaattctt tgttaaaatc aggatgaggc agaaaacttt tgatttctga
    20821 accaaacata aatgttccgt tcatttctgc ataataatat ggtttgatcc caaagtggtc
    20881 tcttgcaccg aataactcat tcttttcatt atcccaaata gcaaaagcaa acattccgcg
    20941 gatcttttgc aataattctg ttccccattc ttcgtaacca tgcaaaagga cttctgtatc
    21001 tgcatgtgtt tgaaaaacgt ggccagctgc aatcaattct tctctcaaag gctggtaatt
    21061 atagatttcg ccattaaaaa taatgatctt tgtccgatct tcattgtaaa taggctgagt
    21121 accgccctct aagtcaataa tacttaatct tctgaatcct aaagcaacat gtttatcgat
    21181 atattctcct gaactattag gtccacggtg aacgattcga tccatcattg tattaataat
    21241 tgtttttttg ttgtccttgt cgttaacaaa acctacaata ccgcacattt aactttcaca
    21301 tcctaatata aaattactgt ttatttcatt catatgcatc ttatcataga ataaatagcg
    21361 gacgaatatt ttctctctta caatttcgtc acgtgaaaac aaaagatgaa agtttctgtt
    21421 tttacagaaa ataaagtccc aatatctaat ttaccatgtt ttcttttttg aggctacctt
    21481 attctcttcg tgttaaaaaa atattagtgg atgctatttc caaaaaaacc agcaaaaaaa
    21541 gacacgacct aaagatcgtg
//
LOCUS       DAFLVO010000051        20902 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.051, whole genome shotgun sequence.
ACCESSION   DAFLVO010000051 DAFLVO010000000
VERSION     DAFLVO010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20902
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.051"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            591..1280
                     /locus_tag="L1U99_001941"
     CDS             591..1280
                     /locus_tag="L1U99_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1212477.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="L1U99_001942"
     CDS             1267..2475
                     /locus_tag="L1U99_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1212478.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="L1U99_001943"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="L1U99_001943"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBN1212479.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="L1U99_001944"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="L1U99_001944"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBN1212480.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="L1U99_001945"
     CDS             complement(6578..7273)
                     /locus_tag="L1U99_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HBN1212481.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="L1U99_001946"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="L1U99_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBN1212482.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="L1U99_001947"
     CDS             complement(8472..8663)
                     /locus_tag="L1U99_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBN1212483.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="L1U99_001948"
     CDS             complement(8684..9574)
                     /locus_tag="L1U99_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBN1212484.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="L1U99_001949"
     CDS             complement(9561..10328)
                     /locus_tag="L1U99_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBN1212485.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="L1U99_001950"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="L1U99_001950"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBN1212486.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="L1U99_001951"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="L1U99_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBN1212487.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="L1U99_001952"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="L1U99_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBN1212488.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14899..15282
                     /locus_tag="L1U99_001953"
     CDS             14899..15282
                     /locus_tag="L1U99_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212489.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15450..16208)
                     /locus_tag="L1U99_001954"
     CDS             complement(15450..16208)
                     /locus_tag="L1U99_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HBN1212490.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="L1U99_001955"
     CDS             complement(16226..17044)
                     /locus_tag="L1U99_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBN1212491.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="L1U99_001956"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="L1U99_001956"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBN1212492.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="L1U99_001957"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="L1U99_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBN1212493.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18172..19506
                     /gene="dnaA"
                     /locus_tag="L1U99_001958"
     CDS             18172..19506
                     /gene="dnaA"
                     /locus_tag="L1U99_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBN1212494.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19704..20834
                     /gene="dnaN"
                     /locus_tag="L1U99_001959"
     CDS             19704..20834
                     /gene="dnaN"
                     /locus_tag="L1U99_001959"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBN1212495.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
BASE COUNT         5979 a         4254 c         3833 g         6836 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgtggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tgtattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gaatcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa aggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggcgatttc ctgtgtattc cgtctcctaa ctattggtat atctgtattt
    17941 tttatccaca gacgcaagag gaaatctatt ggtttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt tgacaactgt gtttttctct tttttctttt tgtcgattgt
    18061 gtggataatt gtaattaaaa aatttttttc ttcggtttct gtggaaaact attgaaaaaa
    18121 atgctaaatt agtactagtt attcactttt taatgaagga ggaggcctta tatggtatcc
    18181 ctcgatgctt tatggaatga attaaaagca acataccaaa aggatttatc gcctgctagc
    18241 tataatacat ggatcgaaac agcgaaccct cgaacccttg atcaaaacca gctcgttgtt
    18301 gaggttccta gcaagattca taaagaatat tgggaaaaaa acctggcgac aaaaatcgtt
    18361 gaagtcggtt atatgttatc aggaaatgag attatccctc gctttattac tggcgaagaa
    18421 gcagagcaag aagaagttat agaagaaaaa aatccaaaag ttgtggcacc tagtccgcta
    18481 aaaaaagcca tgctgaaccc taaatatacc tttgatacgt ttgtcattgg taaaggaaac
    18541 cagatggctc atgcagcagc gctcgttgta gcagaagatc caggttctat ttataacccg
    18601 ctcttctttt atggaggcgt gggacttggt aagactcact tgatgcatgc aattggtcat
    18661 caaatgctgc aaagtcagcc taatgccaaa gtaaaatatg taagcagtga aacttttgct
    18721 aatgatttca tcaattcgat ccaaaacaaa acagcagaag agttccgtca agaatatcga
    18781 aatgttgatt tactgctagt ggatgacatt caattttttg cagaaaaaga agctacgcaa
    18841 gaagagtttt tccatacttt caatgccttg tacaatgaag ggaaacaaat cgtactaacc
    18901 agtgatcggt tgccaaacga gattccgaaa ctgcaagaac gccttgtttc tcgctttgca
    18961 tgggggctgt ctgttgatat tacaccgccg gatcttgaaa caagaacagc gattttacgt
    19021 aaaaaagcgg cggctgaacg tctagagatc ccagatgaca cactaagcta catcgcagga
    19081 caaattgatt ctaacattcg tgaattagaa ggtgcgcttg ttcgagtgca agcttttgct
    19141 gcgatgaata gtgaagatat ttcgactagt ctagctgcag acgcactgaa aacgttaaaa
    19201 tcaggaaaag gacatcctca attgtcaatc ctgcagatcc aagaagaagt ggcaaagtat
    19261 tatcacatcc aattgaaaga tctcaaagga aagaaacgcg tcaaatctat tgttgttcct
    19321 agacaaatcg ctatgtattt ggcacgtgag ctcacagata attctttacc gaaaatcgga
    19381 gctgaattcg gtggcaagga tcatacaacg gttatccatg ctcatgaaaa aatccagcag
    19441 ctgatggatt ctagtgtcag tatgcaaaat gaagtatcag aaatcaaaaa ctttttacta
    19501 aattaatttg tcgattctat caactgaaaa tagcatgtgg ataaaagaaa aaaacgttca
    19561 aaagttatac acactttttc cacagctgtt ttttcgtttc tctcttacgt tttttgagtt
    19621 ttccacagaa tcaacatgcc ctattacttt tattattctt tttaactaat aataaataaa
    19681 caaacattca aaggagatac atcatgaaag ttactttaaa ccgagctagc tttatgcagg
    19741 aattgcaaac tgttcaacga gctatttcaa gcaaaaccac gatccctatt ttgacaggtg
    19801 taaaaatcac actgacacaa gaaggtttga ctttgacggg gagcaacgct gatatatcaa
    19861 ttgaaacttt tttgtctgtt gaaaacgaaa aagcaaatat gcaaatcgaa tctactggtt
    19921 ccattgtttt acaagcacgt ttctttagcg aaatcattcg gagacttcct gaagaaacat
    19981 ttactttaga agttttagaa aataaacaag tagcgatcac ttctggaaaa gcgaatttta
    20041 tcgtaaatgg attagatgca gataactatc ctcatcttcc tgttgtcgaa agccataacc
    20101 agatgaaatt acctgtacac gtattgacta aactaatcaa cgaaacagtt tttgctgtct
    20161 cacaacatga gagtcgtcca atcttgacag gtgtgcattt cattttatct gataattctt
    20221 tattagctgt agctactgat tctcaccgtc taagtcaacg cgtgattcca gtagaacaag
    20281 cggctgatca ttttgatatt gttattcctg gaaaaagttt gatcgaatta tctcgctcat
    20341 taacaaatga agaagaaatc gtcgaaatca gcattatgga aaaccaagtg ttgttcaaaa
    20401 cagaaacgat gtatttctat tcccgtttgc tagaaggaaa ctatccagat accaatcgtt
    20461 tgattccttc aagttttaat acagaggttg aattttctgt tcctagcttt ttagcggcga
    20521 tcgaacgggc ttctttactt tctcatgaag gccgtaacaa catcgttcgt ttatctattc
    20581 gtccagatgc ggttgtttta tacggaaatt cgccagaaat cgggaaagta gaagaaagct
    20641 tgagttatac agcaagcagt ggcgatccat tagatatttc tttcaatccg gattatatga
    20701 aagcagcgtt gcgtgcattt ggagatatga gcatcaaagt gaaatttatc tctgctattc
    20761 gtccatttac attggaacca acggaagatg gcgttcaatt tattcagctg attactcctg
    20821 tacgtacaaa ttaacaatga ttttcaatgt tcttgaaaat ttaattgaaa agaaatagaa
    20881 aaaataaaat tttaaacaga ag
//
LOCUS       DAFLVO010000052        20400 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.052, whole genome shotgun sequence.
ACCESSION   DAFLVO010000052 DAFLVO010000000
VERSION     DAFLVO010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.052"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(387..1853)
                     /locus_tag="L1U99_001960"
     CDS             complement(387..1853)
                     /locus_tag="L1U99_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1212496.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(2144..4228)
                     /gene="cadA"
                     /locus_tag="L1U99_001961"
     CDS             complement(2144..4228)
                     /gene="cadA"
                     /locus_tag="L1U99_001961"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBN1212497.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKKFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TTNIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPLSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKKEDE"
     gene            complement(4753..5112)
                     /locus_tag="L1U99_001962"
     CDS             complement(4753..5112)
                     /locus_tag="L1U99_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HBN1212498.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(5142..5483)
                     /locus_tag="L1U99_001963"
     CDS             complement(5142..5483)
                     /locus_tag="L1U99_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212499.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            complement(5480..6154)
                     /locus_tag="L1U99_001964"
     CDS             complement(5480..6154)
                     /locus_tag="L1U99_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBN1212500.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     KFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(7330..8628)
                     /gene="asnS"
                     /locus_tag="L1U99_001965"
     CDS             complement(7330..8628)
                     /gene="asnS"
                     /locus_tag="L1U99_001965"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBN1212501.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(8668..9858)
                     /locus_tag="L1U99_001966"
     CDS             complement(8668..9858)
                     /locus_tag="L1U99_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBN1212502.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(9879..10406)
                     /locus_tag="L1U99_001967"
     CDS             complement(9879..10406)
                     /locus_tag="L1U99_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HBN1212503.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(10453..13242)
                     /locus_tag="L1U99_001968"
     CDS             complement(10453..13242)
                     /locus_tag="L1U99_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBN1212504.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(13389..13589)
                     /locus_tag="L1U99_001969"
     CDS             complement(13389..13589)
                     /locus_tag="L1U99_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBN1212505.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(14042..14362)
                     /locus_tag="L1U99_001970"
     CDS             complement(14042..14362)
                     /locus_tag="L1U99_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212506.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(14865..15983)
                     /locus_tag="L1U99_001971"
     CDS             complement(14865..15983)
                     /locus_tag="L1U99_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212507.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            16454..17761
                     /locus_tag="L1U99_001972"
     CDS             16454..17761
                     /locus_tag="L1U99_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBN1212508.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            17882..19081
                     /locus_tag="L1U99_001973"
     CDS             17882..19081
                     /locus_tag="L1U99_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBN1212509.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNIFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(19108..20376)
                     /locus_tag="L1U99_001974"
     CDS             complement(19108..20376)
                     /locus_tag="L1U99_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HBN1212510.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVRKGILFLPIVKRMKEKNKV"
BASE COUNT         5906 a         4344 c         3559 g         6591 t
ORIGIN      
        1 aataaatggt gttcaatcag ctgaccttca gcattagctc aaaaagcggc aaaatatgag
       61 gagctatttt tccgtttgtt tctctaatac tcaggtcaaa tcgctgattt tacaacctct
      121 tccttaaacg gtgttccaaa gcttgcatct gcggtaataa gcccagccaa acgaaaaata
      181 tgaggggcta tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac
      241 ctctgattca cggtgttcca gaagtagctt cttcgaaaaa caagccgaaa cttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttgt aacaagtatt tctattttaa ggctgaacca ctgtttctgg ttcagtgatt
      421 tctttgtttt tgtctcgacg agcaattgct ggcaagatca tacctaataa gatcaagacg
      481 attggtgtga tgatattcgt aaataattgg aaccaccatg ctttaggatc agcagtataa
      541 tctacttttg gcaccattcc taggatacat gcaaacgcag tgaaggcaaa gcaccaagca
      601 ccaaagataa aaccgatttt tggattttta acaaatttat attcagaatt gaatttctta
      661 taagctttat tcaacatcat atatgccaag aacacccata ggtaacgcat tggcatgaca
      721 actgagttca agttcgtcaa ccattttact aattcattca tatctttgat accaaaaatc
      781 ggcaacaaaa taatgattcc tactagtata cctgtcagaa gataaccatt caccaatgta
      841 cctttacgat tacgtttacg tagccagttt ggtacaaatt ctggatccgc atctgctaac
      901 aagattttta gtggtgcatc aattgaaaag gctaatgcgg agatttgtcc aatcatgttt
      961 gtcaatgcgt aaatgatcat caatgagtta ccgataccat agtaattacc taaaatttga
     1021 aaagcactgt atgccccatt tgccatcaag tctttaggaa tattatcact agcaaacagc
     1081 atacccattg cgactgagcc taatacagca caaatcccta ccattgctgc taagaagatc
     1141 atccctttag gaaattcctt tgcaggattt cttgtagagt tgacataagg ggatattttt
     1201 tccgcccctc caactgcaaa tactagcatc gaaacggttg tgaaataact gaaatcaaat
     1261 gttggaatat atgttttcac ttgattcata tgtggtgtgg caaattccat cgttggattg
     1321 atgaacggtg ccgttacagc taaaagaata aataagatcg acatgacgaa catcgctgtt
     1381 ccggccagtc cgccaatcac tttcaaagta gaaagtcctt ttgttgataa atataaaaag
     1441 gcaagaaata taataagtga aataactgct accatttgta ctgacatcgt atttacgata
     1501 tttccatttc cttggactgc ccaaccacca gcaatcagaa ttgcttgagg cttttgtgcc
     1561 aaataaggaa tatggacgac ccagtaagtc caagcggcat agtatgccag tcgtttatta
     1621 gatgtcgtat tttcgaccca tgaactgacg cctcctttac tatccttgaa ggctgatcct
     1681 aattgtccaa cgatcaatgc gtatggaata aaataaatgg ccaaaatcaa tagccaagag
     1741 gtgacaactg atactccttg ctgagcatag ttattaacta cattccccat gccccaaacc
     1801 atgttaaatg caattaacgc aacagtaaac cagcgtaatt gtttgttgtt cattcgttct
     1861 ctcctttatg ataaaaattt gttatccaga tgtaatcata ttcaattttt aacaaactta
     1921 caagacagtg ttattttatg tgtgtattct tttatttaat acacatcgtt ttttcatatt
     1981 ttttccatca aaaaaataag ttattttctt ttatttcatt gaccttattg aatttcaagc
     2041 tattttgaat tttctgcaaa attaaaaaca ttagttattt tataatccta tctattttct
     2101 ttacattttt cattaagaaa aggatataaa aaaaagagga cgttcattcg tcctcttttt
     2161 ttacatgcaa gcttcgcatg gcattcaaaa cagctaatac tgtcacccca acatctgcaa
     2221 atactgcatc tcccattgat gcaaaaccaa aagcacctaa ggcaagtacc aaaattttta
     2281 tcccaatagc aaagacaatg ttttgtttga cgattttcaa tgttttcttt gctaaatgga
     2341 ttgcttctgc aatcttcgat ggttgatcat tcatgatgac tacatctgct gcttcaattg
     2401 cagcatcgct tcccaatcca cccattgcga ttcctacatc tgctcttgct agcaccggtg
     2461 catcgttgat tccatctccg acaaatgcgg tctttttatt gtttctttgt aagatttcct
     2521 ctaaccgctg cactttatct tcaggaagca attcgctata tatcttgtcc acgcctactt
     2581 gcttcccgat atgatcagca atttttttcg agtcgcccgt caacatgact gtgttcttca
     2641 caccagcctg ttttaattga accaatgcgt ctacggcatc ttctttcaag gtatctgcaa
     2701 taacaagata accactgtaa ctttgatcga tcgctagata aagcaatgta ccgatttctt
     2761 gacttaaagg aaaagagatt tcaaatcttt ccatcaattt gtgattacct gctaatactt
     2821 gtttgccatc aacttcagct aagatccctt cacctgcaaa ttcctggata ttagttgttg
     2881 gtaaaagcgg acctgcgtag ccttctaaaa cagattgagc aatcggatgt gtagaaaact
     2941 gttctgcact cgcaatatat tgcatgaatt tctttggatc gatttttgta tcgatcgtct
     3001 ggatcgaaaa gtcacctttc gttaatgtgc cggttttatc gaataccact gtctcggttt
     3061 gcgcaagcaa ctccaagtaa tttgaacctt ttactaatac accgatttta cttgcgcctc
     3121 cgataccgcc aaagaaacta agtggcacgg aaatcactaa tgcacatgga catgagatca
     3181 ctaaaaatgt caatgctcga tagatccatt cagaaaacgc cgctccagaa acaacaagtg
     3241 gaggtaaaac agctaataaa acggccaatc ctacaacgac tggtgtgtaa tagcgcgcga
     3301 atttagtaat gaaattttca gctggtgctt ttttactgct ggcattttct actaattcta
     3361 ataatttgct gatagtagaa ttttcataag atttttctac ttgaactaaa aatggtttat
     3421 ttttattgat aaatccgctt aatactgttt caccaacata tacagattta gggactgatt
     3481 ctcctgtaag tgctgacgta tcgactaatg attctccttc gatgatcgtt ccatctaacg
     3541 gtacacgttc accaggcttc acaagtacaa actgaccgat ctgcacgtct tcagggttca
     3601 cggtcatcaa tccttccgtc gtctgcacgt gagctgtttc tggacggatc gccatcaatt
     3661 cgcgaatcga ttttcttgaa tgactgactg ccaatccttg gaaatactcg ccgatttgat
     3721 aaaatagcat cactgctacg gcttctggat attcaccgat caacatagcg ccaatcgtag
     3781 caacagacat aagaaaattc tcatcaaaga tttttccttt gacgatattc atcactgcct
     3841 tcttcactac atcatatcct atcagcagat aaatcaataa ataccctatc aagcgaattg
     3901 gttcattaaa atcaaataat agcaataaag cgatacctgc aagggaaaat aaaatccgga
     3961 acagcgtatt tctctctttt tcatttccat gttcagatac tttttcctta tctatttctg
     4021 ttactttgac atctggttct aattccttca ctactttttt tgtttcttgt tcaatcgtag
     4081 ccaaatgatc ttcctctgcg tcaatcgtta gttttccaga agtgaagttt accgttgctt
     4141 ccttgactcc attgatcttc tgaactcctt tttcgatttt cattgcacag ttcgcacaat
     4201 ctaaaccttc taatctgtaa cttttcattt taatgacctc ctcgcctcaa catatgaaca
     4261 tctcttcata actaattata aatgaatggt tattcatatg tcaaggtatc cgaaagaaaa
     4321 aatgaaaaac atctgcatcg gaaaatttct tccatacaga tgttttggct tattctttct
     4381 ttttctcttc gatcattgcc cctgctctta tccaacccgc acttgccttc ttgatcttga
     4441 caggatagca actaagtttg aagcctgttg ctggcaattt gtctaaattc attaattttt
     4501 cgataggaca atatcttttt tcaatccctg caaaatgtcc ttcccagata ttcgaagctc
     4561 cactacgctt tcaaaaatat agaaagagtt ctttaatgaa aattatttca actttccata
     4621 aacagtaatc ccatataaat aaaagacgta aaagtcacat gggagaactt atacaggaaa
     4681 acacatagag tcaggtgaaa tacatgtatc ccacctgact ctatgcgttt tctaaccttt
     4741 attattctct ttttatacaa tttctgcacc gaatggcatc aacgccaatc gagcaagttt
     4801 gaaagattgc ttggcaaaag gtatccctat gatcgtgata catagaagga tgccgctgac
     4861 gacatgtgcg agagcaattg gtaggcctga aacgatcagc cagatgatat taacgatcaa
     4921 tgacatgcca gactggtgat aaattacttc tttgccaaaa ggcgcaaaag aaagggaggc
     4981 gatcttaaaa cattgcatac cgattgggat acctatgatc gtgatacacc aaagtatccc
     5041 cgctgctaac cagctaagac caccgattag tccgccgaat ataaaccaga tgacatttcc
     5101 taaacaactc attgtatttc tccttctatt actgtttttg attaaaactg ggcaaaaatt
     5161 gattttattc ttcttttttt agcttccagc atcaagtatt ctgcaaattt tttttggatt
     5221 tcttccgtat tttcttttgt tactaatgtg tgttggatta gttttcctga tggtcgctga
     5281 tccacccgtt cttctgactg ttgcacgtcc gcttgcgcaa atccgataat ccgtttttct
     5341 tttgttacag caacgagcaa tagtttattc ttatcattta ggtcagctgc cgtttttgct
     5401 tttacgaatg attctggatg atcagtaatc agctgattga tttgaggtaa atcttctttt
     5461 actgcccacc gtatttccat catttctcac ttttctttcg ctcattttta tctccactaa
     5521 aaaaatcgac tgcggcaatt gcatctatcc agctttgtgc aatgatctca tgtccgccaa
     5581 tcgttgggtg gaccccatct tctcttgtat atttcgaaaa accataagca atccctaaag
     5641 cattgaatat gccatctaaa ggaaccagca atgcgccata ttccttagca agtttacgaa
     5701 caatttggat tttagggtct aagtctttac gccagccatg acggtcgtcg gttataggaa
     5761 gtacaaacgg ctccatcaag atgatgttgc agatttccgc tgtttgaagt tcatttagta
     5821 attttcgata aacggattca aattgctgcg cagatttctc agttccgaat atagcctgat
     5881 cgctagtatt atgccaggta tcattgattc cgatcaaaat cgatacatag tcaggttgta
     5941 aagctaaaca atcttcttgc cagcgtactt gcagatctgc aattttgtct cctcctatcc
     6001 cacggttcat gcattcaaat ttcatcgttg gatattggga gattagtttt ccggcaatca
     6061 aaagtggata acctttacct agatcagttg cttctgctcg gtctcttcct gcgtctgtaa
     6121 tgctgtcacc gataaataat atacgttttt tcatttgtca aaaactcctt tttgaataaa
     6181 acgatgattt tcttccttat attatcccat aagccctatc aagacgaaag agaaaatata
     6241 tgtataaaaa atgacaccag cctagtccct tcaatcaatt gaatgaacgc tcatcaagtg
     6301 tctagttttt tatacttttt ttcttaacgt gccggattcc ccttgattcc ttcgttgttt
     6361 ggtccagaga aatcgatcac acctaagctt ccgtcaatca gaccactgat gacgccatca
     6421 gaacatatat ttataggctc atctaagact tccagtaaat gttcttttac taatatctct
     6481 tctagattgc ttgggataga ttggtcataa ctttatctgg tccgatgatt tcaaggatga
     6541 attaaactta catatggatc attgcatgct gaaaatacgg acctactcca tcttcgaatg
     6601 ttactattag tttgttttca ggtactagat gctgctttat ttcaacagca gaagcatcat
     6661 caaatcagat ttccatttga ataaccttct ttgtatatgt ttgattgatt gcgatttcgt
     6721 tatagaacct tgtgaatcaa atagcaattt cttttgcttt cttctcttgt ctgctggaaa
     6781 cttcctttat cccgtatttt aaaaaaagaa ctgcgagagt tcgcagttct tttttttaaa
     6841 taaacgttgc tctccggcca actcctcggt cacaagtcac aatagtcatc aaacatgaaa
     6901 aactgttttt tgaaattact ccttgtgact cggagctgaa cggcaggcgc acaacctctt
     6961 gatataaacg gtgttcaatc agctgaccct cgatattagc taaaaaaacg gtaaaatatg
     7021 agaagctatt tttccgtttt gtttctctaa tactcaggtc aaggcactga tttcacaacc
     7081 tcttccttaa acggtgttca aaagccagtt tctcggtatt aagccaaatt tatgcaaaaa
     7141 tgtggaaagc catttccaca aaatttttct taatactcga aactaaacag ctttttcaca
     7201 acctctccac taaacggtat tcaaaagctt acatctgcgg taataagtcc cgccaattca
     7261 aaaacatgaa cagctgtttt tgcttggctg ttctaattac ttgatgcaga acagcttttt
     7321 catcacctct tatggataaa ttcggttcaa caaacgtggg aatggaatag cttcacgtac
     7381 atggtcgata ccagcaatcc aagtgactgt tcgttcaagg cctagaccaa aaccagagtg
     7441 cggaacagaa ccgtatttac gtagatcaag ataccatgaa tattcttttt catccaaacc
     7501 gtgattacgg atttgttcta gcaagaaatc atagtctgtt gcccgttcgc ttccgccaat
     7561 aatttcaccg taaccttctg gtgcgatcat atctgcacaa attaccacgt cttctcttgt
     7621 tggatgtggt ttcatgtaga atggcttgat ggcttttgga tagtttagga taaagacagg
     7681 ctgttcgaat gaattcgcaa tgaacgtttc atgaggtgaa ccaaagtctt cgccccattc
     7741 gatgtcatca aatccatttt tcttcagtaa ttcgattgca tcatcgtaag taatacgagg
     7801 gaatggcaat tttgtataag tttttaagac ttctttgtct cgtcctagta catctaatgc
     7861 atattcgcaa tgatctaaaa cattttgtac taagaatgct acatattgtt cctgtacttc
     7921 taaactttct tcttgatgag tgaaagccat ttctggttcg atcatccaga attcgatcaa
     7981 atgacgtcgt gtttttgatt tttcagcacg gaaagtcgga ccgaatgaaa agacttttcc
     8041 gaaagccata gcagcagctt ccatgtataa ttggccactt tgagataaat aagctttttg
     8101 atcaaagtaa tttgtttcga atagatccgt agtgccttct ggtgcagaac cagtcaagat
     8161 cggcggatcg attttgacaa aatgatgttg attaaagaat tcatacgttg cacgaatgat
     8221 ttcatttctg atctgcataa tcgcatgttg tcttgaagaa cgcagccata aatgacgatg
     8281 atccatcaag aaatctgttc cgtgttcttt tggtgtgatc ggataatcgt ggctctcgct
     8341 taccacttcc acatttgtaa ttccgatttc ataaccaaat tttgaacgac tgtcttcacg
     8401 gatttctcca gttactaaca cggatgtttc ttggtgtaga tttttagctg tttggaaaac
     8461 ttcttccgac acttcgcttt ttacaactac accttggaaa aaggctgttc cgtctcttaa
     8521 ttgtaaaaat gcgatttttc cgcttgatcg cttatttgcg acccaagcgc cgattgttac
     8581 tgtttctccc acatggtttt tcgaatcgat gatttgaatt tgttccacgt atgactctcc
     8641 ttttatattc cttgaatttc ttcaggatta attttgactt ttactctcaa taaattgctt
     8701 gattctgcgt accgcttctt ctaacgtagc gcgatcagtg gcataactca tgcggacatt
     8761 ttctggtgcc ccaaagcctt cgccagtcac aagcgctacc cctgtttctt ctaaaagatc
     8821 ttctacccat tgtgtgacat tttcatactt acacatgcgt agcgtttctt ttacattagg
     8881 aaaaagatag aaagctcctt gcggcttttc aagagaaaca cccggcagtt ctgccacaag
     8941 cggatataac gtattcaggc gttcttcaaa ggcgttccgc atttcttcta ctgtatcttg
     9001 ctcacctttc aatgcttcaa cagctgcata ttgactgact gctgtcggat tgctagttga
     9061 ttgggaagca acagcgatca ttccattgat gatcacagga tttcccaccg cataaccaat
     9121 gcgccagcct gtcatcgcat atgttttaga cacgccgttg atgatgatgg tctgattttt
     9181 gattgcttct gaaatcgttg caattggagt aaactcattg ccattataaa ctaaacggcc
     9241 ataaatatca tcagcaacta tcaaaatatc attttttact gcccattcac cgattgcctg
     9301 cagttcattc ttgctataaa tcattccagt cggattcgat ggagaattga tgattacggc
     9361 ttttgttttt tctgaacgtg cttgttctag ctgttcaaca gtaactttcc agctattgga
     9421 ttcttcccct ttcacaaaga caggaagtcc ttctgccagt tttacttgct caccgtaact
     9481 gacccagtaa ggcacaggaa tgatgacttc atcttgcggg tcaaggatcg tttggaaaag
     9541 ggtatacaaa gcaaatttcg ctccgtctgt tacgactgtt tgtgaaggtt catagacaag
     9601 tccatagttt ttcttcagat aatcaacgat tgcctgtcga agctctggga ttcctgctgt
     9661 tggtgtataa tagctagctt tcccattgcg gattgcttcg attgctgctt cttggatgtt
     9721 ttctggtgtc gcaaaatccg gttctcccac agtcaaactc agcacatctc tgccttttgc
     9781 ttttaatgcc ttggcctttg ccgcagctgc caaagtgaca gacggttcta atcgttttgt
     9841 tctttttgat aactccatcc cattcattcc tttacctttt aaattccctt gattgtcttg
     9901 acttcatctc cagattcaaa gccaatcagg taataattca gtttcccatt tgtttctttt
     9961 cctactactt cccacacagg ctgatcatca tacatcccta aagcagcttt ttcgatttgg
    10021 atttcaggat gggccgcagc aattgtctgt tttgcttcgt tttcagtcag tccctttgtt
    10081 tgatccaata cttttacttt ttcaccagat ttaggaatga taacggcgat ttcttttcct
    10141 ttatcatttg tacctgtcag tgaaaagtat gtcttctttc gagtaaacca ataaaaatga
    10201 tcggtttcct caagatttgc atatttcttt gcgatttcta ctgcttcttt cttcgcctgc
    10261 accgccggac gactggaacg caagtaaaaa atcgagctga tcacgatgac cgctaataaa
    10321 aatacgatca agccaagtaa cacgcgatta atcgtttttt cctttgtctg ttttttcttc
    10381 aagggtcgtc gctcctttat cttcattcct tttcattata gcagatttta attatgaaaa
    10441 aagacagctc ctctaacttc cttcttcatt tttctttaag aattcatgga tatcctgata
    10501 gatttcctcc atagctagct ctttgatcgg tacttttttc ggtaatgcat ggatgatccg
    10561 tgcgccatat tttgcagtga ctagtcttcg atccaaaata agcaatacgc cacgatctgt
    10621 ctccgtcctt atcaagcgac ctaatgcttg gcgtaacttc aaagctgctt taggtacgga
    10681 ttcctggtaa aaaggattga tcccctctga ttctaaataa gcgttcctag ctttgaccat
    10741 cgggcgaagc ggattatcga agggtaaacg tgtgactaca acgatctgca aagcatctcc
    10801 aggcaaatct acaccttccc aaaagctgtc agcgccaaac aatacgcttt tttctgacaa
    10861 aatgaagcgt ttcaaaagct tctcccggct tccaccaaac ccttgagcta gtatttctcg
    10921 tcctttttct agcatagaca gatgcatttt ctgatagacc ttctgcaaaa catcatgaga
    10981 agtgaataac acaagtattg gccgatcttc ttgttcgatc agacctgtaa gtgctgtctc
    11041 taaataatcg atatatgctt gattgctgac ttgatggacg gcaggtgcct cttttggcac
    11101 atagatcctt gcctgtttct cataatcata aggagaggca atcactttaa gaggtgctgc
    11161 ttcaatgcca agcctcttag agagatagtg tcgattaggg ccgatcttca gcgttcctcc
    11221 aatataaaga atacgatcat atcgaggata ccaaacagtc gacggcaaca tagccgcttg
    11281 aaaatcatgg agatgaaaaa tcatctgctg cgctgtgttc ccaggaacga accaatggat
    11341 caaatgatct cgccagtctt ccagccattg atccatcagc aagtattgct tgtctaattg
    11401 atcaaatagg ctatataaac ttgctaaatc gatccgcatc tggtttgtcc agctttcttg
    11461 gataatctca aaagtcagac gcatttgtga ctgtagctgc tggatctcct gataaaaaag
    11521 ctgcaggtga tcaatggctg tcccagattc cagtggcagc tgatccaaca tctcttttgt
    11581 catcatgact tcttctggat actgtccgtt aggttgcttg ccgctcacta aactcattaa
    11641 tccttctgcc atacaaatct gtgcttcgca tagcgcagaa agttcttctc gataaatcga
    11701 taaccagcgt aaggcttcat gttctttcgg taaatagctt tgtattcggt caaacagctg
    11761 atttggttct tctaattgct ggatttgttt atggaaatag ttaatactta atcgtttgtc
    11821 atttactttt tcagcgattt ccggcaaatg atgtacttca tcgatcaaca aaaatggact
    11881 agctggaagc aatggttctt ttcgctgtgt ttcttgtact aaaaacgcat gattgacaat
    11941 caaaaaatta ctttgcctga ttttcttttg caagaaacga acaaagtctt gttcgtaaaa
    12001 tgactgattt cttgctaaaa atccaatacc tctgtgcgcg atatctgcaa agaatgaatg
    12061 gttcaaattt gttaaatgta attcatccaa atcaccagtc ttcgtttgcg tcagccaaac
    12121 taagaccgcc atttgataca aagcatattg tttttgttct ggcggttcca caagtgtgcc
    12181 tttaaaacgc tgcaaatcaa tatagtggcg atagcttttg ataattacag gttgtatggg
    12241 ctgatctagc aattgattca gcaatggaat gtctttttct atgatctgct gctgcaaaac
    12301 tagcgaaacg gtactgatga cagcgggttt ttcaggtgta gccaaataac tcaatggcag
    12361 cagataaccg attgttttac ccattcctgt agctgcttcg atcatcaaat cttttgattc
    12421 atcttttgtg aaatggtcgt agaccgcatt catcagtctg ttctgttctt ttcgatacat
    12481 cagtgtttta ccaaacattt tttcttttgc ttgttttttt cttggatatg tccgctcgcc
    12541 ataatggacg gatgtgaata gttccacttc ttttttctgc aaagctagcc catcgacgat
    12601 ttctaatgag ggatcaagtg gctctggttt ttctttcatt tcttcaatca catgataaat
    12661 gaaacgactc gtatccatac ctgtgtgtct acttaatcgc gcaatctgct ctaacgtgat
    12721 gattggcaat tttctcatcc gttcttcgat cagcaaaaga agttgacctg tcacttcggc
    12781 atcactatct gcctgatgag gattctcatg aataaatcca aggctttctg acaaatcagc
    12841 taagcgaaag cttggttccg tcggcaagaa aatttgtgca agttctactg tatcgatgcc
    12901 tggtatcttc aaactaggaa gtccgcatcg catgagttca tggttcaaaa aattataatc
    12961 aaaataaata ttatgcgcga caaatatggt gtctgccaaa agattgtaaa tcgtttgggc
    13021 gacatcttcg aaataaggcg ctttttggac gcgttgattc gtgatccctg ttaaatgctg
    13081 gatttgtttt gaaatcttcc gccctggatg aatatcgatc gaaaaacgtg aagtgatccg
    13141 acctgattca atcatgacgc agccaaattg gatgatccga tcttcttttg gattcgtccc
    13201 agtcgtttcg atatcaacga ctgcataagt tcttggtttc aaaatatctt cctcttctcc
    13261 tgcctctaat gttcttttga aattatacta caaagtgcag aaaaatactc tcatcgcttt
    13321 ttaaagaaaa tagacaaaaa cgcccagaca cgcaaatgtc tgggcgttta ttttttagta
    13381 taggttaatt aagctttagt aacgtttgtt gcttgaggtc cgcgttggcc ttcttcaaca
    13441 tcgaaagtta ctgcttggcc ttcttctaaa gttttgaatc cgtcgccttg gatagctgag
    13501 aaatgaacga atacatcgtt tccgttttct gcagtgatga atccaaatcc tttttctgag
    13561 ttaaaccatt ttactgtacc tgtttccata ataaaaatcc tccttgtgta tcaacacata
    13621 ttttgcaatt acttgaatgg tgtatatctg gaagatgttt atttgaaaca agctaccaca
    13681 gattaccgaa caaaaactac tcctatagta tatcataccg tttacaaaaa agctagagtt
    13741 tttcgacttt ttttattaaa aaaagttttc tcagcgatta cataaagtga aaaaccgaac
    13801 ttttttttaa aataaacgac atattgttca gttggtgttt ttttgctctg atgttctttt
    13861 ttaaactaaa aaaattattc tttctgacta cttatcggtt ctgtttcaac ggtcgaggct
    13921 ggggaagatt ctttagtagg tctgatgttc tcatggtatt tctgatagcc tatgacagtt
    13981 accagaagaa caaggcaaac caatacgacc aacgagatta gtttttcttt tttgctcata
    14041 tctatacctc ataaataaca ggatgatgtc catcatattt ctgagtatga gtaaaagcaa
    14101 aagctgcagc tgtagaatgt aagaaatgcc agcaactttc ataatcacag gtcggacagt
    14161 accaaaagta accaaatctt ggctgcaaag accgttcttc tgtttcagga atcgcagaat
    14221 caagatctgg tgtctgtaca taaacatttt tgtacagacg tgtgcctgta ataggaaacc
    14281 gctgtgtttc ttcagcaaaa actggctgac ttgttaaact tagggataga gacagcaaac
    14341 accataacag tctttttttc ataaagacct ccttatcgat aagtttttcc caattaaaat
    14401 catatctcaa gaacgcccgt tattcacatt ttgttcataa atgatgtttt ttgtatcata
    14461 atcgtcaaaa agaggtcgtg accacgtcac aacctctttt ttaaacggtg ttccagaagt
    14521 agcttcttcg gaaataagcc gaaatttcac aaaaatttga gaaataattt ttgtcaatct
    14581 cttcttattt cttgaagctg accacttctg tcacaacctc ttccttaaac ggtgttcaaa
    14641 agcttgcatc tgcggtaata agcccaccaa acaaaaaata tgaagagcta tttttgcttg
    14701 ctgttcttat tacttgatgc agaacagctt tttcacaacc tctcatacac ggtgtttaat
    14761 cagctgacct tcggtattag ctcaaaaaac ggcaaaatat gtgaaactat ttttccgttt
    14821 gtttctctaa tactcaggtc aaaacactga tttcacaacc tcttttaata acgaagaatc
    14881 gctgtcagac tcttttcatc tggcgcatct ttttgatcca aaataaacac ttttccgcca
    14941 ttaatgatca catcatctgc taatgcattc aacacttgac gccgatcata ttctgtttca
    15001 ggatcttcac cgaaaccatc agctaagttt gacgtagcga taaataaatg tgacactttt
    15061 ccttctttcg cagctggaac gatatcaact aactgatcga tgaatttctt atctaagagt
    15121 ttattgtatt cttttgattc ttgagctgcg agttcacttg acagcttctt cgccccttct
    15181 tcgatatctc taaaggatag ctgcgcagga gaagcagaaa tcgcaacgtc tgcacaataa
    15241 tagggatttt tagcaatttt tttgaacatc gtctgatttt ctggtagagc aaataaataa
    15301 atcggccatt gttctggatt ttcgaaagaa tccttcaagt acgtatcaac tgcttggtaa
    15361 tagttgaccc aatcgatctc tacttcttca tcttttggat ttacgccatg gaaagttact
    15421 ccatctcggg ctccgcctcc tccattagaa gagaagttca aaccgccacc tgtcagttca
    15481 gatcccaatg cagtaacgac atcaaccggt gccccttctg gtagagatac ttcttttact
    15541 tgtttgttgc tgacttcata caatttcatg gagtcgcggt tcaatcccaa taaataataa
    15601 gaatagttga actgcccatt tttgataata gccagtaaat aaggaagatc acttacatag
    15661 tattgatcgt ctaccgggat actcaaacga tggatatagg tttggtcagc agttataatg
    15721 accgctacac tcgtagttgc actacgccaa aacgaaggat ctcctaacaa attttcaatt
    15781 ttttcttgga acggggacca gtcatgttcg gaatattttt tctcaaaacg tttctttgct
    15841 tctttcgcaa aatttttgaa tttgatctga tctttttcca catcttgatg ggcgacatgc
    15901 gtattcagca tgatcgtgac gaatggtcct ttagcgcctt ctgaagtcaa ttgtgacaat
    15961 aattctttat ccttttttgc cataaacgta cccctcctaa aaaaatcatt cctttgtttc
    16021 tatctaaagt ctaccacaac actatttttc catacaataa aacgtatcta aaaaaataaa
    16081 acggtttcta cggttttaaa tttagctatt tttttaagtt atcttcataa tttcctcaat
    16141 tatttagccc cagtcttcaa ctattcttca tgaaatgctg ataaactaag aaaaagaata
    16201 aaagaggtgg atcttatgca tttgattatg attttcagtt tattaagtat tatcagttta
    16261 tttgctttca gcgcttcccg cttattagat gcggaaacac agcctattcc tgtaaaagta
    16321 cgtaaaaacg accgctaacc ttccataacg tgcgttctta tcctaaagtt ttttcagaaa
    16381 cattgaaact ctctcccctc tctgataaaa ttttaatttg tagcgaaaca aattaattac
    16441 aaggagatcg gatatgtcca taaaaaaaac acgtctagtc ctattattgg ctagtctcat
    16501 tctttgcctt gcttcttttc taccagctgt tgctgtgcaa gctgaagata ctttcaaagt
    16561 aaatgcaaaa gcagcctttg ctgtagatgc gcaaagcggt aagattcttt atgatcaaga
    16621 tggagaaaaa accatgggga tcgcttcaat cacaaaaatc atcggtcttt acatcgtcct
    16681 tgatcaagta aaagaaggga aactatcatg ggatgataaa gtttcaattt cagattatgc
    16741 agaaaatttg agtgtcaccc cagatttatc aaatgttcct ttgcataaag aaaacaccta
    16801 caccgttaaa gaattattcg actctgcaat catccagtca gccaacgctt caatggttgc
    16861 cttggcagaa aaaatctctg gcagcgaagc aaaattcact gaacgaatga aagaacaatt
    16921 gaaagattgg ggtatcaaag atgcaacgat cgttaatgca tcaggactga ataactctta
    16981 tcttggcgaa aaccgaccag aaggtactgg agaaaacgac gaaaatcaaa tgtctgctca
    17041 agatgtggct atcgttgccc gtcatttgat cttggatttt ccagaaatac tggatgtatc
    17101 tagcactacg acacaaatgt ttggcgaaaa cacgcaatca ccagtagaaa tggtcaactg
    17161 gaactggatg ctcccaggat tcgtgaatta taaagaaggc gtggacggat taaaaactgg
    17221 tacgactgaa cttgcaggag cctgtttcgt cggtacgatc actaaaaacg atcaacgaat
    17281 catcactgtc gtattgaatg cagacggcca tgcggaaaac ccaagtgccc gtttcaatga
    17341 aacagctcgc ttaatggatt attgctacga caattggtca gaaaaagagc ttggaaaagc
    17401 caatgcaagt atccctagtc taaaaaccat tgatgtaaaa gacggaaaag aatcaacagt
    17461 gcccgttgtg cttaaaagtc ctgtaaaagt atgggtacgg aacgatatgg atactggaaa
    17521 attaacaatc acaccaactc ttgacaaaaa acaagtcact gacaatgaga tccaagcacc
    17581 tatggataaa ggaacaaaaa tcggtaccgc aacgatcacc ttggcagaag ataaattagg
    17641 ttatcttgaa gacaacaacg cgccatccac agaaatcatc acggataaaa ccgtagaaaa
    17701 agcaaatatt ttcgttattg gctggcgacg cgtcgcagaa tttttcggta acttgtttta
    17761 attgaacaaa aagaaaaaag catctttcca tgtggaagat gtttttttgc tttttctagt
    17821 ttaaataaca gcttttttca tctattttcg ttatactgta taagaaaaag gagttgaatt
    17881 tatgaatcta accagagatc tgattttttt ggttctctat cttattgggg tattctccat
    17941 cgtttattgg cgaaaacaga aaaaggatcc ttccttgttc ttttacagca gtacatggac
    18001 gtttgcggta atcttgactt attttgtcgt gttggaaatt ttttattcga ccttttattt
    18061 tttgattccc ttagtgtttt tcagtatctt tgccttttcc tatttttcag aaaagcgaag
    18121 gctgttgaat ggtcttttat tcaatatttt cctcattagt tttggtatct acttgtttgt
    18181 cttgctatac gaaacacaaa atatttttct tggcggactg attgccttga tcacgatccc
    18241 gttactgctt gtctttctat tcggcattta tggattgatc gtttttcttt tttggaacgg
    18301 tgtcacagtt ttacgtagag agtcgcattc attagctaat cttttaacgt tgatactagc
    18361 catttttctt acattgtttc ttgtttttga ctttttcttg ttaaaatatt taccacaatg
    18421 gataaatgct ttgtttttct gcatcccatt gatcttgatc tatctattta tcgtattcta
    18481 caactttttg actgtctcat tcttgtatca gttcaaccgc cctcgataca accaagactt
    18541 catcgttgtg ttaggcgccg ggttgatcaa tggagaaaca gtttctcctc ttcttgccaa
    18601 gcgaatcaat aaggcgattg ctttttattg ggcacaaagc cgtgcgacat taaatccgcc
    18661 tatcctatta atgtcgggtg gacagggagc agacgaaaaa gtaccagaag caatggcgat
    18721 gaaacaatat gccatggaac aaggaattcc tgaaagagat attcttgtcg aaaccaattc
    18781 gacaaccact ttggagaata tgcgctattc aaaggaaatc atggatcagc aaatgaaagg
    18841 tccctatcgc gcgatcttca gttccaacaa ttaccacatt ttcagagctg gtctctatgc
    18901 acgacaagcg aaactgaagg caaatggcat tggggcaaaa acagctttct attacttgcc
    18961 taacgcgttt ttaagagaat acatcgccat cttgatgatg aacaaaaaaa gacatatgat
    19021 catttgcgga ttgcttttcg caggttccgc attcttatca ctgatcactt tacttttcta
    19081 aaaaaacaag gtgtgacaaa acatatgtca caccttgttt ttttctttca ttctcttaac
    19141 tattggcaaa aagagtatcc cttttctgac cgctacttgc tgagcagaat aaataccgct
    19201 gttgcctgaa cacataaagc tgatcaagca gatcataaag aagtatactg ccgcttgtga
    19261 accgaacaat tcgatcccca tcacaaagca ggcaatcggt gtatttgtcg caccagaaaa
    19321 tactccgata aagcccaatc ctgcaagaaa aggaacagaa acatggagca aaggcgctag
    19381 tgctgcacca agcgttgcac caatttcaaa caatggtgtc acttctcccc cttgatatcc
    19441 cgcgcctaaa gacaaaactg tgaagaataa cttcccaata aaatcataga catgtgcctg
    19501 tccattaaat gattcctgca gtaatggaag actcaatccg agataacgtt gtgtttgcaa
    19561 aatcaatgct gcggctacaa ctacagcccc acctatcgta tttcgccaaa caggatgagg
    19621 aatccattgt gcatatcgcg cttttaaaaa gacgatcgaa cggctgaata cccaaccaat
    19681 caaaccaaaa gcaatcccag caacaaaaac tttgaagaac agcaacatac tccattcagg
    19741 aatcacaccc atttggtaat gtagatgaga aacaccatag ctttctgtca taaaatttgc
    19801 aaacagtgca gcaaagaagc tagggaagat cgcttctgtt cggactttcc cgattgccaa
    19861 cacttctaat ccaaataatg ttccagctaa aggtgtgcca aatacagaac taaaacccgc
    19921 actgattcca ctgataatca agatttcccg ttctgattta tccaatcgga acaaacgtgc
    19981 tgtattatct gctaacgctc cccccatttg gactgctgtt ccttcacggc caacagatcc
    20041 tccaaataaa tgggtagtta tggttccaaa cagtgtaagt ggaataagtc gcaacgggat
    20101 tttttcttct ccaccatttc cttgatcgat cactaagttg tttccacgac tagaaagacc
    20161 gccgtgatac gcatagagat aagcaaaaag cgcaccacta actggtagta gataaaggag
    20221 ccaaggatgt gatagtcgga tatctgtcac aactgtcagg ctatttaaga aaaaagcaga
    20281 taagctcccc atgaatatac cgagaatcgc tgtgatcacc agccacttca gcatgtacac
    20341 taaaatgcgt actggactcg gtaattgttt ttccataaaa aattcctcct caataaaaaa
//
LOCUS       DAFLVO010000053        20262 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.053, whole genome shotgun sequence.
ACCESSION   DAFLVO010000053 DAFLVO010000000
VERSION     DAFLVO010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20262
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.053"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(89..1648)
                     /locus_tag="L1U99_001975"
     CDS             complement(89..1648)
                     /locus_tag="L1U99_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HBN1212511.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            1803..4037
                     /gene="pcrA"
                     /locus_tag="L1U99_001976"
     CDS             1803..4037
                     /gene="pcrA"
                     /locus_tag="L1U99_001976"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HBN1212512.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            4054..6090
                     /gene="ligA"
                     /locus_tag="L1U99_001977"
     CDS             4054..6090
                     /gene="ligA"
                     /locus_tag="L1U99_001977"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBN1212513.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            6196..6501
                     /gene="gatC"
                     /locus_tag="L1U99_001978"
     CDS             6196..6501
                     /gene="gatC"
                     /locus_tag="L1U99_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HBN1212514.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            6501..7973
                     /gene="gatA"
                     /locus_tag="L1U99_001979"
     CDS             6501..7973
                     /gene="gatA"
                     /locus_tag="L1U99_001979"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HBN1212515.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            7970..9400
                     /gene="gatB"
                     /locus_tag="L1U99_001980"
     CDS             7970..9400
                     /gene="gatB"
                     /locus_tag="L1U99_001980"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HBN1212516.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            9410..10465
                     /locus_tag="L1U99_001981"
     CDS             9410..10465
                     /locus_tag="L1U99_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBN1212517.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            10576..11949
                     /gene="rlmD"
                     /locus_tag="L1U99_001982"
     CDS             10576..11949
                     /gene="rlmD"
                     /locus_tag="L1U99_001982"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBN1212518.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            11952..12080
                     /locus_tag="L1U99_001983"
     CDS             11952..12080
                     /locus_tag="L1U99_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBN1212519.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            12520..12708
                     /locus_tag="L1U99_001984"
     CDS             12520..12708
                     /locus_tag="L1U99_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HBN1212520.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            12786..13799
                     /locus_tag="L1U99_001985"
     CDS             12786..13799
                     /locus_tag="L1U99_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1212521.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(13866..14900)
                     /locus_tag="L1U99_001986"
     CDS             complement(13866..14900)
                     /locus_tag="L1U99_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1212522.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            15014..17239
                     /locus_tag="L1U99_001987"
     CDS             15014..17239
                     /locus_tag="L1U99_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBN1212523.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            17257..19140
                     /locus_tag="L1U99_001988"
     CDS             17257..19140
                     /locus_tag="L1U99_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HBN1212524.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            19121..20095
                     /locus_tag="L1U99_001989"
     CDS             19121..20095
                     /locus_tag="L1U99_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HBN1212525.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
BASE COUNT         6822 a         3719 c         4342 g         5379 t
ORIGIN      
        1 ttttcccagc ctcttctttt tttatagaat catatagaat caagtagtgt agatgaatag
       61 ttgttgtaaa atagtttttc catgttcgtt aaaatgattg cttcaaattt gtgatagaag
      121 atttagcctc gatttcctgc ttgattcttg gcaagtttgc ttcatcagtc aagataacca
      181 aaatatctcc tacattcatg atcgtatcac cgtgagtcaa gatttcctga tttcctctgc
      241 gtatagagat tagcagcata tttttaggcc aattgaagtc tcgtaccatt aatccgtcta
      301 aagaactctc tgccgttact ggaaaatcaa aagttgtcct tgcacctttt agtgaggcgg
      361 tctgagtatt tccaagtaga cgttccaata atgattcgta aattggatta ccgccgagaa
      421 ggtcattgac gatataagca acaagagcag ccaatcctaa aggcatcaga tgattaagag
      481 agccaaccat ttctgtcact aaaataattg ctgtcagcgg tgcttttcca atcgctgtga
      541 aataaccagc catggcaata acgacaaaat ccttgatgta gattggatcc atcccgaaat
      601 caaccataat gtttccataa aagctaccga ttaaagcccc caatgtcaat atcggaagga
      661 aaatcccccc tggaagaccc ccaccgtaag aaatcatgga aaaaacgaat cgaagaacaa
      721 acaaaccgat aatcataatg attggcaagg aagcatgtcc aaaagctaaa acgatttgat
      781 tgcctccgcc tagagtacta ggccataaat aaccaattgg caaaatcagc aagaaaggaa
      841 cgaacccgtg aaaataagct ggtaaaggca atcggttgta aaattttggc aaagccagca
      901 agacattctg ataaataaaa cctaagatgc ctagaagtac tcctaagatc actaaggaac
      961 cataatattt caacggcaaa gaaggaaggt cacctagata taaaacaggt ctcaagccga
     1021 aaaagtaaag agagacgaag ttagcagtga ttgctgaagc aaatgatgtc agccaaacaa
     1081 gtggagaaaa ggagtgatgg atttcttcta aaacaaagag taatcctgcg ataggagcat
     1141 tgaatgctgc tgcaagtccg ctacttgcac cgctagaaat taaaatcttt tcttctgaag
     1201 atggactccg aaacaattgt ccagctcctt gtccaatgga tgcgccaagc tgtatagaag
     1261 gtccttctct acctagaaaa aggcccgcac caactgaaag tacaccgcca atgaactttt
     1321 tccataaaac agagaaccag ttcattgata attccccgcg aagctgtccc tctacttgtg
     1381 gaatcccgct tcccttgata tccggttcat ttttgaccag ataacccacg aaaaatgctg
     1441 caaggatgca gcaaatagct aggccaatta agtaaatcgg ctgttcccga ctcatttcat
     1501 agatacttcg aactaaatcg cttagctttt cgatagataa tcgaaacagg ctaacgacga
     1561 ttcctgtcag cagtccaaca aatattcctt ttagaataaa atatatctga gtcttatcta
     1621 atttcttgat ttttcctttt ttttccattc aaacgcctcg ctttctttta atttagcgcg
     1681 aaatcaacga attgacaagg aaaaatccat aaaaagaaac aaatgatttt gaactagcta
     1741 gtttaatgaa agccaagaaa atgctataat taacaagatt gataaaagaa aggatgttgt
     1801 taatgtcatc caaagctgaa ttattaaacg ggatgaaccc ccgtcagaaa gaagctgttc
     1861 ttcacactga cggaccatta ctgctaatgg caggtgcagg aagtggaaag acgagagtgc
     1921 tgacacaccg cattgcctat ttgattgagg aaaaagaagt caatccttgg aacatcctag
     1981 cgattacttt taccaataag gctgcaaaag aaatgaaaga acgtgtcaat gcgattctcg
     2041 catctggagg cgaagatgtc tgggtatcga cttttcactc gatgtgtgtg cgtattttaa
     2101 gaagagatgt tgattttatc gggtataacc ggaactttac aatcatcgat tcttctgaac
     2161 agctgacctt gatgaaacgg atactaaaag aactgaacat tgatccgaaa aaatatgatc
     2221 ctcgaagtat attaggaaca atctctcaag caaaaaacag cctgcagacc cctcaggatt
     2281 ttgcaaaaat gcaaggcagt tattacgaag agattgcggc aaaatgttat gctgcttacc
     2341 aaaaagagct tcaatataat caatgtatgg actttgacga cctgatcatg aatacgattc
     2401 gattatttga agaacatcct gattcactca cgtattatca aaacaaattc cattatattc
     2461 atgtagatga gtaccaagat acaaatcacg cacagtatac gctagtcaat ttattggcag
     2521 gtagatttag gaacctgtgc gtcgtgggag atgcagatca aagtatttac ggctggcgcg
     2581 gtgcagatat gcagaacatc ttggattttg aaaaagatta tccagatgct gcagtaattt
     2641 tgctagaaca aaactatcgc tccacgaaaa acatccttag cgcagcaaac caagtcattg
     2701 aaaacaatag caatcgaaaa ccaaaaaact tgtggacaga aaacaaagaa ggaaacaaga
     2761 tcacttacta ccgtgcagat aatgaacgag acgaaacccg ttttatcgta gaccggatgc
     2821 aagaagagat tcgaagcaat catcggaatt acggcgactt tgccatcttg taccggacga
     2881 acgcacaatc tcgtgtaatg gaagaaactc tgttgaaagc aaatattcct tataaaatgg
     2941 ttggagggca caagttctac gatcgtaaag aaatcaaaga tattttagcg tatttgaatg
     3001 tgctggtaaa tcctcaagat tcaatcagtt ttgagcgtat cgttaattcg cccaaacgag
     3061 gcatcggacc aggatctatc gaaaaactac gcagttttgc ttctcttcat gaatggccac
     3121 tgcttgaagc agcgcaaaat gtggatctgg caaatatcgg tggaaaagca ggacagcaat
     3181 taggtgcatt tggagagatg atccaagaag tcactcagat gatcccatac ttgacagtga
     3241 cagaattgac gaaagaggtt ttggatcgta gcggatatct agaagactta aaaatccaaa
     3301 atacattaga agcacaagca cgcatcgaaa acttggagga atttttaacg gtcacacaag
     3361 aattcgacaa acaattcgaa cagcaaaatg aagaagacgc tgatgcacca gaagaaaaac
     3421 taacggtctt cttaaatgat ctggcacttg tttccgacat tgacaattta gaagaagatg
     3481 cttcccaagt gacattgatg actttgcatg cagccaaagg attagaattt ccagttgtat
     3541 tcctgattgg tctagaagag ggggtttttc ctttatctcg agcattgatg gaagaaagcg
     3601 aactggagga agaacgccgt ctcgcatatg tggggatcac gcgagcagaa gaagcgttgt
     3661 atttaacaaa tgctttctcc agaacattat atggacggac gcaatataac cgaccttctc
     3721 gttttgtaga agaaatcgat caggagttac tggaaatcga aggcatgcgt cctacgccta
     3781 aaaaaacgcc tgtattcgct aaaaaaacag catatagcta taaacagcca gagacagcgg
     3841 ttgttccctc taaaagtgct actggagggg aaaataacag ctggaaacct ggagataaag
     3901 tcaaacacaa aaaatggggt ctaggaacag tcgtccgagt aagcgggacg tcgaaggatc
     3961 tagaactaga tgtggctttc ccaagtcaag gagtaaaacg tcttttggct gcctttgcgc
     4021 caattgaaaa agcttagtag tggagggtaa atgatggaac atgaaatgac gattgacgaa
     4081 gctgctaaac gagcagaaga acttcgtaca agactgaacc aatggtctcg cgaatactac
     4141 gtagaagata aaccaacagt ggaagactat gtttatgata aagaatacgc agaattagta
     4201 gcaatcgagg aacaatatcc tgatttgatc acgtctgatt ctcccactca acgagtaggc
     4261 ggaaaagtat tagaaggttt tgaaaaagtc actcatgata ttccgcttta cagtttgaac
     4321 gacgttttca gcaaagaaga gctgatagct tttgatcaac gtgtacaaaa agcagtggga
     4381 cgtgtagttg actattgctg tgaactaaaa atagatggac tttccgtttc tttgcgttat
     4441 gaagatggaa atttcgtgag aggtgcgact cgcggggatg gaactgtagg agaaaacatc
     4501 actgaaaacc taaaaactgt ccggtcggtc ccaatcaaat taaaagaacc aatgaacatc
     4561 gaagtaagag gcgaatgttt catgccaaaa cggtcatttg tccaattgaa ccaagacaga
     4621 gaagcagagg gaaaagatat ctttgcgaat cctcggaacg ccgcagctgg ttctttgcgt
     4681 cagttagatt ctaaaatcac agcgaaaaga aatctggaca cttttttata cacagtagct
     4741 gatttcggtc ctatgcaagc aaaaacccag tatgatgcgc tagaagagct agaaaaaatt
     4801 ggattccaca cgaatcggga aaaacgtcta tgtcattcga ttgatgaagt gtggtcatac
     4861 attgaagaat atcatgacaa acgtgtggat ttgccctatg aaatcgatgg aatcgtcatc
     4921 aaagtgaatg aattctcgct acaagatcaa cttggtttta ctatcaaagc accgagatgg
     4981 gcagcagctt acaagtttcc gccagaagaa gttgaaacgc taatcgaaaa catcgaatgg
     5041 acagtcggtc gaacaggggt agtaacgcca acagctatca tgacaccagt ccgagtagca
     5101 ggaacgacag taagccgtgc cagcctgcat aacggtgatt atattaagtt gaaggatatc
     5161 cgcttgaaag atacagttct gatttataaa gcgggagaca tcatcccaga agtttcgcaa
     5221 gtcgtgttag ataaacgacc taaagacagc gaagaatacc aattgcctac acattgtcca
     5281 gtttgtggaa gtgaacttgt ccatttggat gaagaagtag ccttacggtg catcaatcct
     5341 aaatgccctg ctcaaatgaa agaaggtttg aaccactttg tttcaagaaa tgcgatgaat
     5401 atcgatgggt tggggccgcg cgtactagaa cagatgtatg ataaaaaact agtagcagat
     5461 gttgctgatc tttacaaatt gacagaagaa gagttattga cgttggacaa aataaaagaa
     5521 aaatcagcaa ataatatttt gacagcaatc gacaacagca aagataattc ggtcgagcgg
     5581 ttgattttcg ggttaggaat ccgacatgtc ggagcgaaag cagcaaaaat tttagcagaa
     5641 catttcggtg atctagaaac attgagtaaa agtgactatg agtcgattat tgcgcttgat
     5701 acgatcggtg atatcattgc cgacagtgta gtcacttatt tcagtaacga agaagtccat
     5761 gaattgatga atgaattaaa acaagcaggc gtcaatttcg aatacaaagg gcttcgaaat
     5821 gcccaattgc aagaagtcga gtctcctttt aaagaaaaaa cagtagtcct tactggtaaa
     5881 ctaacacgat ttactcgtga agaagcaaaa gagacgatcg aaaatcttgg cgggaaagtg
     5941 actggtagcg tatcgaaaaa aacggatatc gtggtagcag gagaagatgc tggcagcaag
     6001 ctgaccaaag cacaagaatt aggaatcgaa gtttggacag aagatcaaat ggcagatgca
     6061 ttggctaaaa gtcgctcagt agaagaatga aaaatgagtt ttttcagaca aatttcaata
     6121 aacaatttca gacacggcac tcttgtgtta aaatagagag caaagttttt aactcgttta
     6181 gaaagaaggg gtagtatggc gattagtgaa gaacaagtga aacacgttgc caaattagca
     6241 aaacttgcgt tcgcagatga agaacttgca agttttaccg accaattagg taaaatcatc
     6301 gatatggttg aaatgctgga agaagtagat acggaaggtg ttccatttac gtcgaatgtg
     6361 gttgaaacag taaacgtgat gcgacaagat cgggcgcaag ctggatggaa ccgcgatgaa
     6421 ttattgaaaa atgtgccgga aacagaagac ggctttatca aagtacccgc aatcatcgat
     6481 aatggggagg ctggcgcata atgacagaat tacacaatcg ttctctagaa gaactgcatc
     6541 atatgcttgt atcgaaagaa atcactgtac aagatttgac aaaaacaaca tttgaacgaa
     6601 tcaaagaaac agagcctgag gtcgaggcat tcattacatt gaacgaagaa aaagcattgg
     6661 aacaggcaaa agctttagat gaaaaaggga ttgatgaaag caacgtcctt gctggtattc
     6721 caattggtat caaggataat atcgtaacaa aagatatctt gacaaccgct gcatctaaga
     6781 tcctttacaa ttttgaacca atttatgatg caacggtcat ggataaaatc tatcaagcag
     6841 atatgatccc tgttggtaag ctaaacatgg atgaatttgc tatgggtgga agtacagaaa
     6901 cttcttattt caagaaaaca aaaaatgctt gggacccaac aaaagtacct ggtggctctt
     6961 ctggtggttc tgcagcagca gttgcagctg gacaaattcc agtttcttta ggtagtgata
     7021 ctgggggaag tatccgccaa ccagcagctt ttaacggcat cgtagggatg aaacctactt
     7081 atggccgtgt ctcacgtttt ggtttgattg cctttgcttc atctcttgac caaatcggac
     7141 caatgacccg tacggtgaaa gataatgcat tagcattgac agctatcagc ggttatgacg
     7201 aaaaagacgg tacttcttca ggcgtttcag ttcctgattt tgcagaggga ctgacaggcg
     7261 acatcaaagg aatgaagatt gctttaccta aagaatactt aggcgaaggt gtggcccctg
     7321 gcgtaaaaga agctgtattg aaagcagcag aaacattccg ttcattaggt gctgttgtgg
     7381 aagaagtcag cttgcctcat tcaaaatacg gtgtggctgt ttattatatc attgcctcat
     7441 cagaagcaag ttccaatttg caacgattcg atggtatccg ctacggttat cgctctgaaa
     7501 atgtgaaatc attagatgat gtatatgtca actcacgttc agaaggattc ggtgaagaag
     7561 taaaacgccg tatcatgtta ggtacattct ccttaagcgc gggttattat gacgcttact
     7621 tcaaaaaagc aggacaagtc cgtacattga tcaaacgaga ttttgaaaaa gtctttgcag
     7681 attatgactt gatcatcggg ccatcttcac caacagttgc attcggaatc ggtgagaaca
     7741 ttaacgatcc aatcacaatg tacatgagtg acatcttaac gatccctgtc aacttggctg
     7801 gacttccagg tatgtctgta ccggcaggtt tatcagaagg attaccagtt ggattgcaga
     7861 tcatcggtaa ttattttgat gaaaaaacga tgtatcaagc ggcatatgcg tttgaacaag
     7921 caacagaatt ccataaacaa caaccagcta ttttaggagg gaaagacgaa tgaattttga
     7981 aacagtcatt ggactagaag tccacgtcga gttaaaaacc aactcaaaaa ttttctctcc
     8041 agcgccagct cattttggtg cagaaccaaa cagcaataca aacgtgatcg actggggtta
     8101 tccaggcgtg ctgccagtaa tgaataaagc tgcgctggaa ttcgggatga aagcagcttt
     8161 ggcattaaac tgtgaaatct ctaaagatac tcattttgac cggaaaaatt acttttaccc
     8221 agataatcca aaagcatatc aaatttccca atttgatcaa ccaatcggtc atgacggatg
     8281 gatcgaaatc gaagtagaag gtaaaaagaa aaaaatccgg atcgaacgtg tccatttaga
     8341 agaagatgct ggaaaaaaca tgcatggtat tggcggttat tcttacgttg atttgaaccg
     8401 acaaggcacg cctttgatcg aaatcgtttc tgaagctgat atgcgttcac cagaagaagc
     8461 atacgcttat ctagaagcat tgcgatcaat tatccaattt acagaagtca gcgatgtgaa
     8521 aatggaagaa ggctctatgc gctgtgatgc caatatttct cttcgccctt atggacaaga
     8581 agagttcggt acgaaagcag aattgaaaaa cttgaactct ttatctttcg tgaaaaaagg
     8641 tttagctttt gaagaaaaac gtcaagcaaa agttcttctt tcaggaggag aaatccaaca
     8701 agaaacacgc cgttttgacg aaacaacgaa taaaacagtt ttgatgcgtg tcaaagaagg
     8761 gtctagtgat tatcgttact tcccagagcc tgatatcccg aaattcgtga tcgatgacga
     8821 atggattcaa aaagtaaaag ctagtttgcc tgagatgcca gcttctcgtc gcgaacgcta
     8881 tatccgtgag tttggacttc cagagtatga cgcaatggta ttgacactta caaaagaaat
     8941 gtctgatttt tttgaagctg ttttggaaaa tggtgcagat gccaagcaag catctaactg
     9001 gttgatgggt gaagtttctg cttacttgaa cagtgagaaa ctggaattag ctgagacaaa
     9061 attgacacct gagaacttag caggaatgat tcgtttgatc gccgatggaa cgatcagctc
     9121 aaaaatcgcc aaaaaagtct tccgtgaatt gatcacaaat ggcggagaag cccaagaagt
     9181 agttgaaaaa aatggttggg tgcaattatc tgatccgaac aaactactgc caatcattaa
     9241 tgaaattttg gataacaacc aacaatctgt cgatgatttc aaaaatggaa aagatcgtgc
     9301 ggttggcttc ctagtcggtc aaatcatgaa agcaactaaa ggacaagcaa atcctggtgt
     9361 cgtgaataag ctacttaaag atgaattagc gaaacgatag aggctgaaaa tgaaaaaagc
     9421 acgcgtaatt tataacccca cctcgggaaa agaattattg aaaaaaaatt tggcggatat
     9481 cctacaggca ttagaagaag caggatttga agccagcgcc tatgcaacta caccagaacc
     9541 agattcagcc aagaatgaag catgtagagt cgcagaacta ggttttgatc tagtagtggc
     9601 agctggtggc gatggcacaa tcaacgaagt ggttaatgga atcgctccgc ttgaacaccg
     9661 tcctaaaatg gccatcatcc cagctggtac aacgaacgac tatgctcgag cattaaaaat
     9721 tcctagagat aatattaaag cagcagcaga agtgataaaa aaacaccaaa ccgtaaaaat
     9781 ggacatcggc ctttctgata acagttactt catcaatatc gctgcaggtg gctatttgac
     9841 agaattgact tatgaagttc catcagaact aaagagtatt tttggttatc ttgcttatct
     9901 tgcgaaagga gcagagatgc tccctcgagt aaagccaatc aaaatgcgct tgaagtatga
     9961 tgaaggggaa tatatcggaa atgcttcgat gtttttccta gggctgacga actctgttgg
    10021 aggattcgaa cagatcgcgc cagatgccaa attggatgat gggaagtttt ctttaatcat
    10081 tgtgaagaca gcaaatatct ttgagatctt gcatattgca gcactcatgc tgaatggcgg
    10141 tcgacatgtc gatgatccaa gaataatcta taccaaaaca agcagtttgt tcgttgaaac
    10201 agaagatgat atcaatcgac cagtaatgat caacttagat ggtgaatacg gcggggaagc
    10261 accgatgcat ttccaaaatc ttcatcaaca cattgagttc tttgccaata ccgatcagat
    10321 tcctgatgaa gcaatcacag gtacagatga agaagaatta gaggttgtca gcaaagaatt
    10381 cgtaaaagaa gtcgaacgtt taacggatga agatatcgac ggtgacggaa aaatagcaga
    10441 cgaaacacct aatcaaaaga attaatcaaa agccggtgct gaacgtagta aggtcagtgc
    10501 cggttttagt tgtgtaatta gctgatttat agtagagttc agtaggattg aaaaataggc
    10561 ttaaaggagc aaaatatgac agaacagcaa atagtaaaga aaaacgaacg atatacagtc
    10621 gaaatcgtcg acttgagtta tgaaggaatg ggggtagcaa aaatcgatgg ttatccatta
    10681 tttatcgaaa atgcactccc tggagaagaa gtagaaatac tagtagtaaa agcaggcaat
    10741 aagtttggat atggaaaagt cgaaacattt attacacaat cacctgatcg tcagcctgta
    10801 gaaaacaatg cattacttcg cataggtatc gcacctttag cccatttgaa gtatgaacaa
    10861 cagcttgtct tcaaacaaaa acaagtagag catgtaatgg cgaagattgc taagatgcca
    10921 gaagttcctg tacttccaac ggtcggaatg gcagaaccat tcggctaccg taataaagca
    10981 cagatccctg ttcgccgtat cgatggacag ttagccaccg gtttttacaa aaagaatagc
    11041 catgatctag tccctatcga agatttttat atccaagatc ctgtcatcga tcaagcaatc
    11101 aaagtagtca gagatatctt gcaacggttc caagtacgag gatataatga agaaaaaaat
    11161 gaaggacagc ttcgtcacat cattatccgt cgtggtcatt attcccatga aatgatggtc
    11221 gttttagtta ctcgtaaaga aaaattcttt aaatccaagg aaattgctga agctattcat
    11281 gaagaattgc cagaagtggt ttcggtcatc caaaatatca atgaagaaaa aacaaatgtg
    11341 attttaggag acaaagaaaa agttttatat ggcagagact atatcgaaga tcagctatta
    11401 ggaaaaacct atcgaatctc agcaaagtca ttttatcaag taaatactca acaagcagag
    11461 tatctgtacc aaacagccat cgagtttgcc gagttagata aaaaagacat tgtgatcgac
    11521 gcttattcag gaataggtac gattggcttg tctttagcag acagagtgga taaggtgtat
    11581 gggatggaag ttattccaga agcaattgaa gatgcacagt tcaatgcttt aaataataaa
    11641 atcgaaaatg ttcattatga agtcggaaaa gcagaaaaag ttatgaaaaa atggcaagaa
    11701 aaagggatca aaccatctgt gatcgtagtt gaccctccac gaaaaggatt agatcatcat
    11761 tttattgaat cagcaatcga aatgtcacca gaacgaatcg tctatatctc atgtaatccg
    11821 gcaacttttg caagagatgc taagttattt gcagaagcag gttatgccgt gaagaaagtt
    11881 cagcctgtag atcttttccc gcaaacccat catatcgaat tagtcgcttc attcgttaaa
    11941 ggagaataaa aatggaccaa aaagaaaaaa tgaaagaatt gatcaaaaag aaacaaggtg
    12001 gaggccgatc caaacaaatg gaaacaccta agaatgatcg taaaaacatg agaaaaggcc
    12061 ctaaaatctt taataaatag acgtgctaaa gaaagactaa gaagtgttaa cttttgttat
    12121 tgtttcttag tctttttagt tagtctacat tattttggcg atttgccaat aaggactgtt
    12181 gagttgtgca aaatcaaatc tgggtcagaa tgaacgtcat tctgtctcag atttttcgtt
    12241 atttcaattt gattaactga ttgatcaaaa agatttttat tttcatattc tcaaatgatt
    12301 caacactaaa tatacatgtt tgacgcggaa attattattc gattttggcg gcatcagggg
    12361 ggatgacgac gtagcagacc cattatttta ctcaagaaaa tgtccgtgcc tattatttag
    12421 aatacgatag tgaacgtgct gggagttttg ttcttttaga gaaagtctct gaagataaat
    12481 tagttgtctt agattttgac tgtaacgaaa aatggcgaaa tggaagagca ccagcaagtg
    12541 attgaccgga tctacgaagc gacacgatat ctgcctttgg atcgtttgtg cttaagtcct
    12601 caatgtggat ttgcttcaac agaagaagaa aatgttttgt ttgaagaaca atggaaaaaa
    12661 tttcttttgt caaaagcatt gcagaagaag tttggggaaa atcattaaat catctaggag
    12721 agcttgatag gaaataacac tatggtataa tcagaatgct taatactaac tactgaggga
    12781 gccttatgaa aaagaaaatt cttaaattta tcggatggtt cttcggaatc attcttggga
    12841 tcgcgtttgc aatctttctt gccttccagc tttcccccag acctggagca ttcttgatca
    12901 accatatgtt ttcaaatact gttcaaatca ctgataaaaa aacgttcgat caagcagaaa
    12961 aaaacgtggc gaaaaaaaca gatttgacgt atgagtccaa gtataaagag aatacttatg
    13021 acatctacta tccaaaaaac agcaaggggc ctgttcctgt tctattttgg gtacatggtg
    13081 gaggattcgt cggcggagat aaatcgggtg tcaaagaatt tgcgacaaaa ttagtttcag
    13141 acgccaacat cgcagtggtt gcgatgaatt atgaattagc gcctgattca gaatacccta
    13201 atcaagttct tcaagtgaat gaactgatca aagatttatt agctgaagaa aaagacgaca
    13261 aattgctaga catggaacaa ttattttttg gtggagatag tgcaggttca caaatcgcat
    13321 tgcaatatgc agctatacaa acgaatgatg cgtatgctaa acaaatgaaa atcaaacagc
    13381 tacttccaaa agatagtctg aaaggaacca tttcttattg cggacctgtt gatttgaagc
    13441 taacagcaca gcagcattcg gatgatcgat ttatgaagtt tttcgtcaaa accgttgcgt
    13501 ggtcgttgat tggaacaaaa gattggaaaa cgagtgagca attgaaagaa gctagtgtgg
    13561 ctgaccatgt ttctaaggaa tttccgccaa cgtatataac tgacggaaat gcatactcat
    13621 tccaggagca aggtcaagca ttagaaaatc ggttgacaga attaaaggta cccgtgcaat
    13681 ccttgtttta tacagataca aaaaaagaga ttacccatga ataccaattt gattacacgc
    13741 taaaagaatc gcaaaattgt taccagcaga cattggattt tgtgaataag tataagtaag
    13801 aggttgtgaa aaagccgttt cgttttgagt atgaagaaac gaagcggctt ttcacaacct
    13861 ctctttcaat acctttttgt tcttgggata aaactttccc taacaatcaa tcgtgcagga
    13921 taagtcaaaa tgattggttc gtcccgtata ccgtcaattc gctccaatgc cattcgaaca
    13981 gctgcttgcc caattgattt cgcattgatt tgaacactgg tcaagccagg ggagaggttt
    14041 gcgattgtct cgatattatc aaagcttgct acaacaatct cttctccaat ttggatattt
    14101 ttttgtttca atgcccgata gacaccaatt gccattggat cgctcccgac aagaatggca
    14161 gtaggaagag gggattcatt ttctaataga ttagtcgcaa gtacctcacc ttgtttttct
    14221 gtccagccac ctagatgata agacatatat ttttctaagt gatgatcgat cataaaatgc
    14281 tgataggcac gcatcctctt ttcatttata gaaatctgct tcccaccgaa ttcatccata
    14341 tcgactttat atcccccgat ataggctatt cttttatgac cattttctaa gaacaattcc
    14401 agtacggttt tagtcatccg ttcaagatct gcatacacca tatcgacctc ttgctggatg
    14461 tcagggttat ccacgacgac tatttgcatg ttttgtttta acaaggcggt aatcgattct
    14521 ttcgtaacag tcccaacaac gatcaccgca cctaactgat ctagatcttc ccattgttta
    14581 ggattatcag atagattata gattcgattc atccctaaat gcagacgtcg agcttcttct
    14641 tccatcccta ctcgcaaatg tttgtaatag atatcctgtt cttcgctcgc tttgccgatc
    14701 gtagagatca caccaatcga aggcattctc tttttgatat atttacgagt actgatgtca
    14761 taatccaacg cagcagctgc ctctactatc cgttgccgag tagtctgagc cacatggatc
    14821 gtctgatcgt tattcaacac acgggaaact gtagcaggag agacatttgc ctttcgtgcg
    14881 acatctctaa ttccaaccat ttttacacac tcctcaaaaa aataaaaaat ttttattgac
    14941 aaaattgttt agtaaacagt atacaggaat tataaaaaaa gtaaacggtt tccgttttgt
    15001 tgggagtgaa atgatggata ttacgcatag aaaaacagat aaaaatttca tcttatttga
    15061 tgaaaagagc cgagtcttcc atttacgaaa tacatttctt tcttatctga taaagataga
    15121 agaaagcaat gtattggcgc atatttattt tggcaaacca gtcaagcagt acaaagacaa
    15181 taaaaattat ccccgaagag atcgtggatt ttcaggaaat gttcccttaa atcctgaccg
    15241 gtctctgtcg aaagatacac taccgcaaga atactcttct catggcagca tggactttcg
    15301 aacgcccgca tcgatcattc agcgcaagaa tggatcagac ttactggatc tgagatatga
    15361 cagccattat attacagatg ggaagccaga gatcgaaggc ttgcctcaaa cttatgtgat
    15421 ggacaagtca gaggcacaaa cgttggtgat ttcacttaag gatagagaaa cagcgattta
    15481 tttcgatttg ttctatacca tatttactga tagagcagtg atcacacgat ctgtaaagat
    15541 aagaaatgaa accggagaaa caatcaaact agaaaaagcg gctagtttcc agctagactt
    15601 tgcccatact aggcgatttg atgaagtcat tgctttgcca ggagcacatg tcaatgaaag
    15661 acagatttca cggcaatctg ttttatctgg aacaaaagta tttgaaagcc gtcgaggaac
    15721 gagcagtcac catatgaata actttattgc tttagttcat catcatacga cagaaaatac
    15781 tggagaagcg atcggacttc aatttgttta ttccggcaac cattctttcg aacttgaaaa
    15841 agatcagatc aatcaattga gagtcgtcgg tgggatcaac agccatcgtt tttcgtggga
    15901 attgaatgca ggccagtctt ttcaaacacc tgaaatgatc ctttcttact caagtcaggg
    15961 attgaacaaa atgagtcaga tccaccatga gttgctacgt gaaagaatcg caagaggtcg
    16021 tcatcaattt gctgaacggc cgattctggt caataactgg gaagccactt actttgactt
    16081 caatagtgaa aaaatcaagg cgatcattga tgaagcaaag gagctaggca tcgaaatgtt
    16141 cgtattagat gatggctggt ttggaaaaag agatgcggac aattcttcat taggagactg
    16201 gttcgagtat gaaggcaagt tgacaaatgg attacgtgaa atagcagatt atgctcatag
    16261 caaaggattg aaatttggtt tatggtttga acctgaaatg atctcggttg attctgaact
    16321 gtatcgaaca catcctgatt ttcttatgca ggagccaggt agaatgcctt ctgcttccag
    16381 atcacaacat gtactggatt ttacaaggtt agatgttcgg cagacgattg agaaacaaat
    16441 gagaaagatt ttagatacga ttcctcttga ctacatcaaa tgggatatga accgttcgct
    16501 ttcagatgtc tattcgatta cccttgaccc acagagacaa ggagaagtag cgcatcgtta
    16561 tatgctcggg ctttatgaac tacttgaaca tttgacaact gattatccgg aaatcttatg
    16621 ggaaggctgt tctggtggag gtggacggtt tgatgccggg tttatttatt atatgccgca
    16681 gtcatggaca agtgataaca cggatgcagt ggagcgtatg aaaatccaat atggaacaag
    16741 ccttgcttat ccgatttcgt ccatcacagc tcatgtatca gctgtaccaa atcatcagac
    16801 cgacagatct acttcgttga aaacaagagg agaaacagct atgagcgctg tttttggtta
    16861 tgaactggat ttgacaaagc tgtctcctga agaaaaaaag caagtaaaag accaaattat
    16921 atcctatcaa acgattcgtc cggtgatcca gtatggccat tattatcgtt tggcgagtcc
    16981 ttttgaagaa aatattgccg catggatgtt tgtgtctcct aaacaagatg aagctattgt
    17041 gtttttaggg aggatactag cttcagctca accagcgttc catgaagtat atctgatggg
    17101 gttagatgat gaggcacttt atcaggaaca gacctcgaag cggatatttt cgggggccga
    17161 attgatgaca gttggacttt acttccccga ttttcaaggt gatttccaaa cagaactgct
    17221 tcatttcaaa aagttatgag agagaaggaa aaaagtatga aagcaaatat aaaatggtta
    17281 gatgatccac aagtttttag agtgaaccaa tcaaatgcac atagcgatca tgtttgttat
    17341 gcaacaaggg aagaagtaga aaccacatcc tcccttaaac agtctttaaa tggatcatgg
    17401 cgtttttgtt attcgccaaa tccttcggta cgaccaaaaa cattttataa aaaagatttt
    17461 gatgcctgtt cttttgatga aatcactgtt cctagtcata ttgaattagc aaattatgac
    17521 aagatccatt acatcaatac gatgtatccg tgggagggac atgtatttcg ccgtccccct
    17581 ttcacgacaa gccctgagaa agaggcggaa gggatctttt cagctgctaa agacaatccg
    17641 gttggttcgt atttgacgac ttttcgatta gaagaaggtc taaagggaaa acaaatctcg
    17701 attcattttg ctggtgtaga acaagcaatg tttatttggt tgaatggtca ttttatcggg
    17761 tatgccgaag attcgttcac tccgtctgaa tttgatttaa caccttattt ggaagaagaa
    17821 aatattctag ctgtggaggt ttacaaaaga agtacagctg cattcttgga agatcaggac
    17881 tttttccgat tttttgggat cttcagagat gtcttcttag ttgctcgagg acaaaaccat
    17941 ttagaagatc tttggatcaa acctcgctta gatgacaaat gtcaaaatgg caaacttgaa
    18001 gtagatttgt cttttgagca agtagccaaa aacagtcagc tgaatgtagc gatactagat
    18061 cctgatggga aggaaatcta tcaacagcaa tatccgttaa aagagcaaat gacgattcgc
    18121 atcgatggat ttgaaaatgt ggcactgtgg gggcattttc agcccaattt atataagctt
    18181 gaattggaga cgatagacga agaaaaaaga gtaacggagt atattgacta ttccttcggt
    18241 tttcgtaaaa tcgaaatcaa agataaaatc atctacttca atggaaaacg gatgattatc
    18301 aacggggtaa atcgacatga gtggcatccg aaaaaaggac gcgccatcac tatagaagat
    18361 atggaaaaag atttggctat cataaaaaat gcaaagatca acggcgtacg gacatctcat
    18421 taccccaacc agatcacttg gtattattta tgcgaccaag caggaatcca tgtgatggcg
    18481 gaaacgaacc tcgaatccca tggctcatgg caaaaaatgg gcgcatttga gccttcttac
    18541 aacgtaccag gtgcagtacc tcagtggcag gcggctgttc ttgatcgagc aaaaacgaat
    18601 ttcgaaacat taaaaaacca tccaagtatt cttttttggt ctcttggaaa tgaatcttat
    18661 gcggaagaaa acattcgaca aatgaacgat tacttcaaaa aagtagaccc cgatcgactt
    18721 gtccattatg aagggaattt tccaaatcca gcattcgaag attcgatttc agatgtaaaa
    18781 agctgcatgt atgcgccacc agaagagatc attgactacc ttgaaaataa agcggaaaaa
    18841 ccgttcatct tatgtgaata tatgcatgac atggggaatt cgttaggtgg aatggattct
    18901 tacatgacgt tgcttgatcg ttatgaaatg taccaaggag gctatatatg ggattttaaa
    18961 gatcaggcga tccaagtgac tgatccaatc acaggcagag aagtgatgcg ctatggcggt
    19021 gactttgacg ataaaccaag tgactatgaa ttctcaggga atgggatcgt ttttgcagat
    19081 ggacaagaaa aacccgccat gcaggaggta agatattatt atgaaaaata cagtaaataa
    19141 aagtcatatg gatacggaaa aagttgcaat cgtcttcggc gactgtacat taggtgtcaa
    19201 atcggggaat acgcattata ttttttctta tacaagaggc ggactggaat cgctcaataa
    19261 aaacggaaaa gaatggctat accgggaaac acttccagtt ttttggcgag caacgaccga
    19321 taatgacaga ggtagcggat ttggatttaa atccggtatg tggttaggag ccggattgta
    19381 tccaaaagtc aaagaaatag aagtactggt ggacaataaa aagatcgatt tgccgattgc
    19441 tccagtaaat aatcaatatt caagtaatga atacgctgaa acggttgaaa tcatttttac
    19501 actggaaatc aacacagtac caaaaaccca agtgacaatt tcctaccaaa tcgctggaga
    19561 gggtaaaatg cttgtcaata tgcattatta tggacaaaaa ggattaccgg aattacccgc
    19621 attgggttta aggttcatta tgccaacgaa agcaaaattt tttgagtatg aaggcctatc
    19681 aggggaaaca tatccggatc ggatggctgg tggtgtcgaa ggtatttata aagtggcagg
    19741 actccccgtt tccccatacc ttgttcccca agaatgcggc atgcatatgg aaacgaaatg
    19801 ggtagaacta acaagaaatc aaacgttgga taatacggat aaagatcaag aagatttttc
    19861 gttgcgattt gaacagcagg atacgccatt tgctttttcc gctttaccat tcaaagcaga
    19921 agaactggaa caggcaacac atatagaaga actaccgcca gaaagacgaa cggttcttac
    19981 gatttttgca aaagtaagag gagtcggggg tatcaatagc tggggagcgg atgttgagtc
    20041 accttaccga atcagcagcg aagaggacca tgaaatcggc tttattattc agtagcaatc
    20101 tttagattat tatttgaaaa acggagttta caagacaaag ctgctttatt ctatatgtca
    20161 tgaacaagag agtaaaaaag ttctcagata cttttgttca tgactatttt cttcaataaa
    20221 accaattgtt atttttctga aaaacaaagt taactatcag aa
//
LOCUS       DAFLVO010000054        19995 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.054, whole genome shotgun sequence.
ACCESSION   DAFLVO010000054 DAFLVO010000000
VERSION     DAFLVO010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19995
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.054"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            30..842
                     /locus_tag="L1U99_001990"
     CDS             30..842
                     /locus_tag="L1U99_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBN1212526.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            839..1639
                     /locus_tag="L1U99_001991"
     CDS             839..1639
                     /locus_tag="L1U99_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBN1212527.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1800..3068
                     /gene="rseP"
                     /locus_tag="L1U99_001992"
     CDS             1800..3068
                     /gene="rseP"
                     /locus_tag="L1U99_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBN1212528.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3136..4845
                     /locus_tag="L1U99_001993"
     CDS             3136..4845
                     /locus_tag="L1U99_001993"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBN1212529.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            5057..9415
                     /locus_tag="L1U99_001994"
     CDS             5057..9415
                     /locus_tag="L1U99_001994"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBN1212530.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            9560..10033
                     /gene="rimP"
                     /locus_tag="L1U99_001995"
     CDS             9560..10033
                     /gene="rimP"
                     /locus_tag="L1U99_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBN1212531.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10056..11231
                     /gene="nusA"
                     /locus_tag="L1U99_001996"
     CDS             10056..11231
                     /gene="nusA"
                     /locus_tag="L1U99_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBN1212532.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11253..11546
                     /locus_tag="L1U99_001997"
     CDS             11253..11546
                     /locus_tag="L1U99_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBN1212533.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11543..11854
                     /locus_tag="L1U99_001998"
     CDS             11543..11854
                     /locus_tag="L1U99_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HBN1212534.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11867..14173
                     /gene="infB"
                     /locus_tag="L1U99_001999"
     CDS             11867..14173
                     /gene="infB"
                     /locus_tag="L1U99_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBN1212535.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14200..14547
                     /gene="rbfA"
                     /locus_tag="L1U99_002000"
     CDS             14200..14547
                     /gene="rbfA"
                     /locus_tag="L1U99_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBN1212536.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(14704..14877)
                     /locus_tag="L1U99_002001"
     CDS             complement(14704..14877)
                     /locus_tag="L1U99_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1212537.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            15325..17687
                     /locus_tag="L1U99_002002"
                     /pseudo
     CDS             15325..17687
                     /locus_tag="L1U99_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            18055..18978
                     /gene="truB"
                     /locus_tag="L1U99_002003"
     CDS             18055..18978
                     /gene="truB"
                     /locus_tag="L1U99_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBN1212538.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            18982..19923
                     /gene="ribF"
                     /locus_tag="L1U99_002004"
     CDS             18982..19923
                     /gene="ribF"
                     /locus_tag="L1U99_002004"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HBN1212539.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
BASE COUNT         6853 a         3519 c         4389 g         5234 t
ORIGIN      
        1 ggaatctttt aagtatagga ggaaaaagaa tgttacgttt ttttccgcaa aaaaacaaat
       61 atattcaaga aaaaagcgaa tttcaattta ataccgatgg accaattcct cagcacattg
      121 ccatcatcat ggacggcaat ggtcgttggg cgcaaaaccg tcgtttgcca cgagttgctg
      181 gccataaaga aggcatggaa acagtaaaga aagtcacaaa aaaagcatca aggcttggag
      241 tgaaagtgtt gacgctttat gccttttcga ctgaaaactg gaagcgacca aaagatgaag
      301 taagttttct catgcaacta cctgtcgact tctttgatac gttcgtacca gaattgatta
      361 aagaaaatgt caaagttcat gtcatgggtt atgaaaacgt attgccagaa catacgcaag
      421 atgctgtaag acgtgcaatt gagcaaacaa aaaacaatac tggaatggta ttgaattttg
      481 ctttgaatta tggaagcaga gcagagatcg tgactgctgt ccaagaaatt gccgaagaag
      541 tagcaaaagg agaaatacac gcagaagaaa tcgatgatga attgattgct aagcatttaa
      601 tgacaggttt cttgcctaaa gagttacaag atcctgagct gatgatccgt acaagtggag
      661 aagagcgaat tagtaatttt ctgttatggc agatcgcata tagtgagctg tattttacaa
      721 aagcgctttg gcctgatttt gatggtgcgc atcttgaaga agcaatcgcc tcttatcaaa
      781 atcgagaccg tcgattcggc ggtgtaaaaa aaacagaaga tgagaaaggg gatcagtcat
      841 gaaacaacgt gtggtcacag cagccgtggc gctagtcttg tttattccga ttatatggat
      901 cggaggcata gcggttgagc ttacagcagc aatcttagca gtaataggag tttacgagct
      961 gtttcggatg aaaggattga cactcttaag ttttgaagga gttttatccg ccgttggtgc
     1021 agtgttactt gttttgccaa aagaaagatg gtttttcttt cttccagaga atgtaagtac
     1081 atttatgtta ttttatctta tagttatgat tcttttagga acatcagtta tttctaaaaa
     1141 tacgtatacg attgatgaag caggttttcc tgtgcttgtc agcttgtatg tgggaatagg
     1201 tttccagaat tttgtcaatg cacgaacaga aagcttggct gttttgatat ttggtctatt
     1261 tattgtttgg gcaactgata tcggagcata tatggttggt cgacgttatg gtcagcataa
     1321 gttaagtcct gatatttcgc ccaacaaaac gattgaaggt gcgctcggtg gtattggtag
     1381 tgctgttgta gtcgcatttc tttatttatt gctataccca gcaaaagaac tatttaatca
     1441 tggtatgttt gtcatgcttc tgatgacgat tattttttca gcagtcggac aatttggtga
     1501 tttggtcgaa tctgcaatca aacgtcatta tgatgtgaaa gactcgggaa atatcttacc
     1561 aggccatggt ggaatcttag accgtttcga cagtttgctg tttgtatttc ctatcatgca
     1621 tttatttggc attatttagt aagtatacct gcgtttcttt gtgaatttca taaaagacgc
     1681 aggtttttat ttttcattat attgatacta ttggtgtctt tggtatacta tggtaaaatt
     1741 atagtgtttt atcgttgttt tataaaaaac acaaaaaaca agtaaaggag aaaaaagcta
     1801 tgaaaacgat tctgacattt atcatcgttt ttggtatatt agtgattgtt catgagtttg
     1861 gtcatttctt ctttgcgaaa cgatcaggaa tcctcgttcg cgaatttgct atcggtatgg
     1921 gtccgaaaat ttatgggcat caagcaaaag acgggacaac atatacgctt cgcctattac
     1981 ctattggcgg ttatgttcga atggcaggca atggggatga tgaaacagaa atggcaccag
     2041 gaatgcctct ttctctttta ctaaattctg acggcatcgt agagaagata aatttaagta
     2101 agaaaatcca attgacaaat gctatcccga tggaattgag ccgttatgat ttagaagatg
     2161 agctgactat cactggttat gtgaatggag acgaaacaga agtagtaacc taccctgttg
     2221 atcacgatgc gacgattatt gaaaacgacg gaacagaaat cagaattgcg ccaaaagacg
     2281 tacagttcca atcggctaaa ttgtggcagc gtatgctgac caactttgct ggacccatga
     2341 ataactttat tttggcaatc ctgttattca tcattctggc atttatgcaa ggtggtgttc
     2401 aagtgacgaa cactaatcgc gtaggagaga tcatgcctaa tggagctgcg gcagaagcag
     2461 gcttaaaaga aaatgatgag gtagtcagtg tggacggaaa agaaatccat tcatggaatg
     2521 atctgacaac agtcattacg aaaaatccgg ataaaacatt agactttaag atcgaacgag
     2581 aaggtcaggt gcaatctgtc gacgtgacac cgaaatctgt agagtcaaat ggcgaaaaag
     2641 ttggccaact tggtataaaa gccccaatga atacaggttt tatggataag atcattggag
     2701 ggacgcgtca agctttcagc ggttcattgg aaattttcaa agccttagga tcactattta
     2761 caggtttcag tttagataaa ttaggcggac ctgtcatgat gtaccaattg tcttcagaag
     2821 cagcaaatca aggtgtaaca actgttatta gtttgatggc gcttctttca atgaatctcg
     2881 gaatcgtcaa tctgcttccg attcctgcct tagatggcgg gaaattagtc ttgaatattt
     2941 ttgaagggat tcgcgggaaa ccattaagtc aagaaaaaga aggaatattg acattagctg
     3001 gctttggatt tttaatgttg ttgatggtgc tagttacatg gaacgatatt caacgattct
     3061 ttttctagaa aaagttgaca aatagggtat aataacaaac gataactatt ttgaggaaat
     3121 aaaggagtat atagaatgag acaatcaaaa atgttgattc caacattacg cgaagttcca
     3181 aatgatgcag aagtattaag ccatcaaatc ttgctaagag ctggatatat ccgccaagta
     3241 tcagcgggta tttattcata tctgccatta gcaaatcgtg tattggaaaa actgaaacgc
     3301 attatgcggg aagaatttga aaaaatcgga gcggtagaaa tgctgatgcc tgccatcttg
     3361 ccagcagaac tttgggaaga atccgggcgt tacgaaacat atggaccaaa cttgtatcgt
     3421 ttcaaagacc gcaatgatcg aaaaatgatc cttggaccaa ctcacgaaga aacttttact
     3481 gatttgatgc gtaatgaaat caattcatat aagaaattac ctttaaatct ttatcaaatc
     3541 caacctaaat atcgtgacga aaaacgacct cgcttcggtt tgcttcgcgg aagagagttt
     3601 atcatgaaag atgcgtattc tttccatgca acggaagaaa gtttggacga gacatataaa
     3661 gattacgaaa aagcctacac cgaagtattc aagcgttgtg gcttagaatt tcgctcgatt
     3721 atcggagacg gtggcgcaat gggcgggaaa gactcaaaag aattcatggc gatctcagaa
     3781 atcggggagg atacgatctg ttattcgact gaaagtgatt atgctgcaaa cttggagatg
     3841 gctacaagct actatgtatc aaaaaaatcg catgaaacac agcttgaatt ggagaaagta
     3901 gctacaccta acgtaaaatc aattgacgaa gtagcagatt tcttttctgt tgaacctcaa
     3961 aaaatcatca agtctgtatt gttcattgcg gatgaacaac ctgtccttgt tttggtacgc
     4021 ggagaccatg aagtcaatga cgtaaaactg aaaaactttt tatctgctga ctttttagaa
     4081 gaagcaacag aagaagaagc acaaaaatat ctaggtgctg agtttggttc tgtcggacca
     4141 gtcggtgttt cagatgacgt aaaagtatat gcagaccgtt atgtccaaga tttagcgaat
     4201 gccattactg gagcgaacga aacaggattc cactataaaa atgtgaatcc agaacgcgat
     4261 ttcactgtac tttcttatga agatcttcgt tttgtacaag aaggagatcc ttcaccagac
     4321 aacaatggtg ttcttgcctt tactcgagga atcgaaatcg gacatatctt caaaatcggc
     4381 actcgttaca gtgaatctat gggagcaact gtactagacg aaaatggacg agaaaaattt
     4441 gtgattatgg gctgttatgg tatcggtgta agtcgtttat tatcagcaat cgtagaacaa
     4501 cattcagatg aacaaggaat caactggcca aaaggaattg cgccatttga tttgcatatc
     4561 gtccaaatga atctaaaaga cgaataccaa acaaacctga cgaatgaact agaagaagcg
     4621 atgacaaaag ctggctatga agtactggtt gatgacagaa atgaacgcgc aggagtgaaa
     4681 ttcgcggatt ctgatttgat tggctgtcca atcagaatca ctgtcggtaa aaaagcagtg
     4741 gatggaatcg tagaagtgaa aatcaagaaa actggcgaaa tggttgaagt acgtaaagaa
     4801 gaattggtga atactttacc aatcctcttg aaccaaggcg aataataagc gttaaaacac
     4861 agaaaataaa aatagctgaa tcagctgttt ttgacaatct gatgattcgc ttttaaaatt
     4921 ggaactgcga tttgaatcgc agttccaatt ttttaatgta aaactcagaa aaaacgagta
     4981 tactaaaagg tactgaaaaa gaagaggata agatgcgatc aattgcattg tttctcatca
     5041 gaaagggcgt atatctttgt cagaaaaacg agatttattt gaaaaactgt tggaacaaat
     5101 ccaactagag gaagcagaaa aaaatcatcc actgcttact gctggtgaaa tggatagtgt
     5161 agtggtccat cgtaaatcgc gtttatggga atttacgctg catttttcca aaattttgcc
     5221 tattatgcta tatcggtcat tgactcagca tctgactatc gcttttaaag atattgcaca
     5281 agtcaaactg aatatcttag cagatgacca gacattcgat gaacagctct tgcaagatta
     5341 ctgggcccaa gctttggaaa atcagcaatg cgatacacca ctagcacagc aagtattgaa
     5401 aacgcaggta cctgtgataa aagatcgtaa agtcatcttg ccaatcgaca gtacaggagc
     5461 tatttcttat ttgaagcaac aatacttgcc attagtagaa gagttgttcg tcagttacgg
     5521 attcccaaaa tttcgtatcg aaccagaagt ggatgagcag caagcggaac gagtattgaa
     5581 actttttgaa gaacgcaaac aagaacaggc agaagccttt atgaagcaag cagctgaaag
     5641 tctagttgtc cacgaacaaa agaaaaagga aagaaaagag caatcgccag ctcttgaagg
     5701 acccatccac atccagctag gacgaaatat tccagccgat gaaccaacga caccaatgat
     5761 cagtatcgtt gaagaagaac gaagagtcac acttgagggg tacgtattcg acaaagaagt
     5821 cagagaacta cgttcaaaac gcaagatctt gactttgaaa atcacagatt atacttcatc
     5881 atttatcgtc aaaaaattct cgaacggcga aaaagatgaa caagtatttg atgcgatcag
     5941 tgtcggtagc tggttaaagg tacgaggaag tattcaagaa gatacgtttg tccgtgattt
     6001 ggtcatgaat gcgcaagata tcatagaagt caaacataca cctcgcaaag attatgctcc
     6061 tgaaggggaa aaacgagtag agcttcatgt tcatagcaat atgagtacga tggatgcaac
     6121 aaacagcatc tctgatcttg tggcacaagc agggaaatgg ggacaccgag ctatcgccat
     6181 tacagaccac ggtggtgcgc aagcctttcc ggaagcacat agtgctggaa aaaaagcagg
     6241 tgtgaaaatc ttatacggcg tggaagcgaa tgtcgtagat gatggtgtcc caattgctta
     6301 taatgatgca catgaagcat tgagtgaagc cacatatgtc gtatttgacg tggaaacgac
     6361 aggattgtct gcagtatatg acacgatcat cgagctagcc gcagtcaaaa tgtataaagg
     6421 aaatgtgatc gaaagctttg atgaatttat cgatccagga catcctttgt cacgaacaac
     6481 ggtagatctg actggtatca cggatggaat ggttcgagga tcaaagtcgg aagaagaagt
     6541 attgcggatg ttccttgaat tttcaaaaga tacaattttg gtagcccaca acgcggcttt
     6601 tgatatgggg ttcttgaata ctagctacgc aaggtatggt attcctgaag cggccaatcc
     6661 agtcattgat acgttggaat tagctagata tctgtatcct caattcaaac gtttcggatt
     6721 aggtgtgtta tctaaaaaat ttggtgtcag cttggaacag catcaccgag caatctatga
     6781 tgctgaagca actggtcact tagcatggat ctttgtgaaa gaggcaatgg acaatcataa
     6841 catgctttat catgatcagc taaatgagca tatcggagaa ggagattctt acaaaagggc
     6901 tcgacctttc catgtaacga ttttagcaaa aaatcaggca ggactgaaag atttgttcaa
     6961 actgatttca atgtcgaatg tcgaatactt cgaacgcgtc ccacgaatac cacgctccca
     7021 attgaaaaag atgcgtgaaa atctattgat cggctcagct tgtgataagg gagaaatatt
     7081 cgaagccatg atgcaaaaag gggtagaaga ggcaagaaac cgagcaaaat tctacgatta
     7141 tattgaagtt atgccaaaag cggtctatgc gcctttgatc gagcaagaat tggtaaaaaa
     7201 tgaacatgat ttggaagaaa ttatccaaaa tttggtagaa atcggaaaaa gtttggataa
     7261 aatcgttgtt gcaacaggta atgtacatta tctgaacgaa gaagatgcca tttaccgaaa
     7321 aattttgatc aattctatgg gcggagcgaa tccgttgaat cgtcatagtt tgccggatgt
     7381 ccatttccga acaaccgatg agatgctaac tgcatttcac tttttagggg aagaaacagc
     7441 gaaagagatc gtagtagaaa atacgaataa aatcgcagat atctgcgaag aagtgattcc
     7501 agtcaaagat gaactttata caccgaagat tccaggttca gaagatgaaa tatcagaatt
     7561 gagttacaca aaagcaaaac aaatgtacgg agatccgtta cctgagatca ttcaaaaacg
     7621 attaaaaaaa gagttgaatt ctattaatgg taatggcttc tcggttattt atctgatcgc
     7681 ccaaaaacta gtgcataaaa gtaatgaaga tggctatcta gtaggttcac gtggctctgt
     7741 tggctctagc tttgttgcga cgatgacagg aatcactgaa gttaatccgt tagcccctca
     7801 ttattattgt ccagagtgcc aatattccga gttttttgaa gatggtacgt atggttctgg
     7861 atttgacatg ccagaaaaac aatgtccaaa atgtggtgca cgcttaaaca aagacggtca
     7921 tgatattcca tttgagacat ttttaggatt ccatggagac aaagtgcccg atattgattt
     7981 gaacttctca ggtgattatc aagcagaagc ccataactat acgaaagtat tgtttggcga
     8041 agactatgtt taccgtgccg gaacgattgg tacagtcgcc gacaaaacag catatggcta
     8101 tgtaaaagga tacgaaaggg acaataatct gcagtttcga agtgcagaag tcgacagatt
     8161 agcaaaaggc gctactggag tcaaacggac aaccggccag catccagggg ggatcatcgt
     8221 tattcccgat tatatggatg tctatgattt tacgccgatc caatatccag cagacgatca
     8281 aaattcggaa tggaaaacga ctcattttga ttttcactcg attcacgata atgtattgaa
     8341 attagatatt ctagggcatg atgacccaac tgttattcgg atgcttcaag atttatcagg
     8401 gatcgatcca caaacgatcc ctacggatga cccggaagtg atgcggatat ttgccggtcc
     8461 tgaagtactt ggagtaagtc aggaacaaat ttattccaaa acagggacat taggtattcc
     8521 agaattcggc actcgttttg ttcgagggat gctagaagaa acgcatccta caacttttgc
     8581 agaactactg caaatttccg gactatctca tggtacagac gtatggttag gaaatgcgga
     8641 agaattgatt cgacgaggag atgcgacact ggcggaagta atcggctgtc gtgatgatat
     8701 tatggtttat ttgatccatg ctggattaga tagcgggatg gcatttaaaa tcatggaaac
     8761 tgttcgtaaa ggacaatgga acaagatccc tgatgaattg cgagaaacct atctatcggc
     8821 gatgaaagaa aataatgtgc ccgactggta tatcgattct tgttcaaaaa tcaaatatat
     8881 gtttccgaaa gcccatgctg cagcttacgt attgatggct cttcgtgtcg cttatttcaa
     8941 ggtttatttc cctattttgt attactgtgc atacttttct gtacgtgcag acgactttga
     9001 tctagtctcc atgtgcaaag gaaaagatgc tgtgaaacaa gcaatgaaag aaatcacgga
     9061 caaaggatta gatgcttccg taaaagaaaa gaatcaactg acagtgctgg agttagccaa
     9121 tgaaatgctg gaacgaggat tcaaatttgg aatgattgat ttgtataaat cggatgccgt
     9181 taactttgtt attgaaggtg atacgttgat cgcaccattt agagctgtcc caagtttggg
     9241 aaccaacgtg gcaaaacaaa tcgttgaagc aagaaaagac ggtccatttt tatccaaaga
     9301 agatcttgcc acccgcggta aagtttcaaa aacattgatc gaatatatga acgacaatgg
     9361 cgtattgaaa gatctaccag atgaaaatca attatcgtta ttcgatatgc tataagcatc
     9421 tgttttcctg tctgcttgta attttaagca gagtatggta tagttcttat aggtaatgat
     9481 actaactgtg agtgagcgga tttttcgctc actcttttta atggaattac gcacttaatt
     9541 ttttaaggag gcgaaacttt tgagtagcgt cgttgaaaca gtcacagaaa tggtgacacc
     9601 gattttagat gaacaaaatt ttgaacttgt cgaagtcgaa tttgtaaaag aaggaaaaag
     9661 ctggttctta cgagtattta ttgacaaaga aggcggtatc gatatcgaag aatgcgcctt
     9721 tgtcagtgag aaactgagtg aaaaacttga tgcagcagat ccagatccga ttcctcaagc
     9781 ttatttcctg gaggtatcct ccccgggagc agagcggcca ttgaaaaaag aaagcgacta
     9841 tgaaaaggca cttggtgatt atgtccatgt ctccttatac caaccagtag atggcgaaaa
     9901 acaatatgaa ggatttcttc aatcatttga tgctgaacag cttacattga aaatacgcat
     9961 aaaaacacga gaaaaagaat tgacttttga ccgaaaaaat attgcaaaag ctcgcttagc
    10021 tatccaattt taatcacgga gaggaatcag aaaaaatgag taaagaaatg ttaaatgcgt
    10081 tagacgcttt agaagctgaa aaagggatct caaaagaaat cgtgatcgat gctttagaag
    10141 cagcattggt ttctgcatac aaacgtcact atggccaagc acaaaacgtc gaagtggaat
    10201 ttgatcagaa aaaaggaaag atccatgtct atgcggtaaa agaagtaacg gaagaagtga
    10261 tggattcaca gttggaagtc tcattgaaag atgcactttt aatcaatcca gcatatgaga
    10321 tcggtgatac gatccgtttt gaagtaacac caaaagattt tgggcggatc gctgcgcaaa
    10381 cggctaaaca agttatttta cagcgtgtac gtgaagcaga aagaacgatt atttataacg
    10441 aattcagtgc ttatgaaaaa gacatcatgc aaggaatcgt cgaacgccag gataaacgtt
    10501 atatttatgt caatcttggt aaaattgagg cagttctttc taaacaagat caaatgccaa
    10561 atgaatttta tcaaccacat gatcgaatca aagtttatgt ttcccgagta gaaaatacgt
    10621 ctaaaggtcc gcaagtattt gttagccgca gccatccaga cctattgcgc cgcttatttg
    10681 agcaagaagt accagaagtc tatgatggaa tcgttgaaat tgtcagcatc gcccgtgaag
    10741 ctggcgatcg ttcaaaagtg gcagttcgct caaatgatcc aaatatcgat gcagtcggta
    10801 catgtgtcgg gccaaaggga caacgagttc aagcaatcgt caatgaatta aaaggcgaaa
    10861 acatggatat cgtcgaatgg aatgaagatc cagctgtatt cattgcaaat gcattgaatc
    10921 ctgcacaagt catggatgtg atcttcgatg agacaaatcc aaaggcctgc acagttgtcg
    10981 ttccagacta ccaattatcg ctagcaatcg gtaaacgcgg acaaaacgca cgtttagctg
    11041 ctaaattgac taaccataaa atcgatatca aatcagaatc tgacatgacg gaattttatg
    11101 aaaatcaaga acaacaaaaa gaaacagaag aactgcatga tgaagcaatc gttcagtcag
    11161 atttaacaga cgatgaatat gaaacaattg cattcaacaa tgaaacggtc gaagaaaaac
    11221 cagaagctta actttagtaa ggaggcaaag agatgaaaca aaggaaaatt cctttacgca
    11281 aatccgtggt ttcaggtgaa atgaaaccta aaaaagagat ggtccgaatc acccgttcaa
    11341 aagaagggga agtatcgatc gatccaactg gaaaaatgcc tggacgagga gcgtatgtct
    11401 cacttgagcc ggaagaagta caacaagctt gggataaaaa aattctcgat cgagtactcg
    11461 aaacaacatt aacagatgag ttttatcaag aacttcttga ctatgtcact caccaaaaag
    11521 cacgtaaaga gttatttgga aaatgaatac agttaatcgg caaaaagcca tgaatctcat
    11581 cggtctagcg atgcgcgcgg gaaaactaat cacgggtgaa gaactgacca ttgctgaaat
    11641 ccgcaaacaa aaagcaaaat tggtgtttgt ggcaaccgat gcaagcgaga atacaagaaa
    11701 aaagataaaa gataagagtt catattatga agttccttgc tttgagctat tttctgaagc
    11761 agaaatcacg cagatgatcg gaaaacctcg caaggtattc ggaataatgg atgccggatt
    11821 tgcgaagaag accaaggagc taattgaagg ttaggaaggt gattgcatgg gcaacaaaag
    11881 aatctatgaa ttagcaaaag aactcaaaaa atctagtaaa gacgtcgtgg aaaaagcaca
    11941 acaacttggc atcgatgtga aaaaccatat gggtgcgatt actagcaatg atgagaagaa
    12001 attgcaacaa gcgttcaaaa acccaagcac gaaacaacaa gctgcacaac aagcaagcag
    12061 aaaaccagcc aatcaacagc cgaacgatca acgtaaaaaa gaaacaacga acaatcaaca
    12121 aaaaaataaa aataaccgca gttatcaaga tcgcggtcaa gggagcggtc aagtgaatca
    12181 aggaaaaaaa ccaacaacaa accaaaataa tacgggaaat accagcagcc aaaatcgtca
    12241 aggaacgagc caaggcggca atcaaaaccg tactaacaat aacaacaaac caaacaataa
    12301 caatcgcggc aaatttaata ataataaccg taatcgttat aataaaaaag gtaaaaaagg
    12361 caaacagcaa caatcaacta aaccagctgt accaccacgc aaattccgtg aattgccaga
    12421 tgtattagag tatactgaag gtatgaacgt agcagatatt gcgaaaaaaa ttcatcgtga
    12481 gccagcagaa atcattaaaa aattatttat gcttggtgtc atggtcaatc aaaaccaagc
    12541 actggataaa gatacgattg aactgttagc gacggactat ggcatggaac cacaagaaaa
    12601 agtccaagtt gacattgctg atatcgataa attcttcgag gcagaagaag tcgatccaga
    12661 taaattagtc tcacgtccgc cagtcgtaac gattatggga cacgtagacc atgggaaaac
    12721 aactttattg gatacattac gccattcacg tgtaacaagc ggcgaagccg gcggaatcac
    12781 acagcatatc ggtgcctacc agatcgatat tgatggtaaa ccaatcactt tcttggatac
    12841 accaggacat gcggccttta caagtatgcg tgcacgtgga gcaagtatca cagatatcac
    12901 gatcttagtt gttgctgcag atgatggcgt catgccacaa acagttgaag caatcaacca
    12961 tgccaaagct gcaggcgttc caatcatcgt cgctgtaaat aaaattgata aaccaggtgc
    13021 aaaccctcaa catgttatgc aagaattaag tgagtatgag ttaattcctg aagcatgggg
    13081 tggagaaacg atctttgttg agatctcagc gaaattcggc caaaacatcg aagaattgct
    13141 ggaaatgatc ctgttagtcg cagaagtaga agatttaaaa gcagatccaa cacaacgcgc
    13201 aatcggaaca gtgatcgaag cacgtcttga taaaggtaaa ggtcctgtgt caaccttact
    13261 tgtccaagaa ggaacacttc atgttggtga cccaatcgtt gtcggtaata cttacggacg
    13321 tgtccgtgta atgacaaacg atcttggccg tcgcgataaa gaagcaggac ctgcaacgcc
    13381 agtagaaatc actggcttga atgatgtacc tcaagcaggt gaccgtttcg tagtcttcga
    13441 agacgaaaag acagcacgtg cagcgggtga agaacgcgcg aaacgtgcat tattagaaaa
    13501 ccgtgctgcc acaagccgtg tgactttgga taacttattt gaaagcctga aagaaggcga
    13561 attgaaagaa gttaacgtaa tcatcaaagc agatgtacaa ggttcagcag aagcactggc
    13621 tgcatcattg aagaagattg atgtggaagg tgtccgtgta aaaatcgtcc attcagctgt
    13681 cggagcaatc aatgaaagtg atgtaacctt agcagcagcc agcaacgcta ttatcatcgg
    13741 tttcaacgtt cgtcctacac cgcaggcaaa agtgcaagct gatactgaag aagtcgatat
    13801 tcgtcttcac cgtatcatct ataaagccat cgaagaaatc gaaactgcga tgaaagggat
    13861 gctagaccct gaatttgaag aaaaaatcac cggtcaaatg atcgttcgtg aaaccttcaa
    13921 agtttctaaa gttggtacga ttgcaggtgc ctatgtaaca gaaggatata ttcgtagaga
    13981 tagcggtgtc cgtgtaatcc gtgacggaat cgtaatctat gaaggccaac ttgcaagtct
    14041 gaaacgattc aaagatgacg tgaaagaagt caaaatgggt tatgaatgtg gtgcaatgat
    14101 tgaaaaattc aatgacatca aagtagatga cgtaattgaa ggatttatca tggaagaagt
    14161 caaaaatgac taaaaactga taaaaggagg ccaatcatta tggctaacta ccgtgaccgc
    14221 cgagtcggtc aagaaatctt aaaagaagtc aatgatattt tgcgcaaaaa ggtccgtgac
    14281 cctcgtgtgg agaacgtaac gatcacagat gtgaaagtta cgggggactt acagcaagca
    14341 acgatctatt acagcatttt atctgactta gcatcagata agaaaacagc acaagatgga
    14401 ttgaataaag catcaggatt gattcgtcga gagttagggc acaatctaag tatttataag
    14461 acacctgaat tgttctttga acttgatgaa tcagttgtct atggcaacca tatcgatgaa
    14521 ttgcttcgcg acttgaacaa agactaatca aaaactcccg caaatcctgt gaaatcaggg
    14581 gttgcgggat ttttttgttt tcattaagac gtattaccta agagttccat gactttagtc
    14641 ttgcggcgtg tcagctaacc aaaaaagaga aaaagaaaag taaaaaattc gactttcttt
    14701 tttctagtag tatataaatt tttgcatata gataaagatc aagataccga taacggaagc
    14761 tagattgtaa tctattttag tgacagtcag gtatagccaa gtaactagaa gatcagtgga
    14821 acctgcacca taaaagtttg agtttgtcgg tccgttgaca gttaaaagaa aaatcacgtt
    14881 gaagttattg atatttccga ttacgccgct tcgatttggt cacgatccaa attttggata
    14941 atccctgtag aaattagcat agtagctggg ataccaattc acatattgac aaagataaca
    15001 gagactttta cataaaacgg atcaatcagg aaaggaattg ctcgatccag ccccagtttt
    15061 ccagcaatgt gttaactggc ccagcgtcat tcagcaaatt atgcatgatg aggagcgaaa
    15121 tgaactgcgg aacagccatt gtgataacga caagtttttt ggatcaatgt aaaaaacgtc
    15181 agcgaaagga aaaatttcgt ggttttttat acctgttcat ttggctagat ataaaatcca
    15241 aacaaatgaa cagaagtgct tattaggttt caattgggag tatctgcgct agaataagag
    15301 taataatgaa aaggagtgtt atgtatggat tattctagta aagaatactt tgataaaatg
    15361 acggcttggt ggcgtgctgc taattatctt tctgttgggc aactttatct taaagataac
    15421 cccttactga gacgtacact gaaacccgaa gatgtcaaaa aacatccaat cggtcattgg
    15481 ggaacgattc ctggccaaaa ttttatttat gtccatttga accgagtcat caataaatat
    15541 gatttgaaca tgttttatat tgaagggcca ggacacggcg gacaagtcat ggtatcgaat
    15601 gcttatttag atggaagtta cacagagatc tatccagaag taacggaaga tgagacagga
    15661 atgcaaaaat tattcaaacg attttcattt cctggaggca ttgcttctca tgcagcacca
    15721 gaaacaccag gttctatcca tgaaggcgga gagcttggat actctctttc acatgcagtc
    15781 ggagctgtat tagacaatcc tgaagtaatc tctgctgtcg tgattggtga tggtgaagca
    15841 gaaaccggtc ctttagctgg aagctggttc tcaaatgtct ttatcaatcc agtgatagat
    15901 ggagctgttt taccgatcct tcatttaaat ggtgcaaaaa tagccaaccc aacgatcttg
    15961 gcacgtaaat cagatggaga attagcaaat tactttaacg gacttggctg ggaacctttc
    16021 tttattgaag gaaatgattc agaaaaatta aatcctgtta tggctgaaaa aatggatcaa
    16081 gcaatcgaga aaattaaatc catccaaaaa gaagctcgcc tgaagacagc aacagatgtc
    16141 gtgatgccaa aatggccagt attgatcgta cgcacaccaa aaggatggac cggtccaaaa
    16201 gaatgggacg gggaaccaat tgaaggaacc ttccgagcac accaagtacc gattcctgta
    16261 gatcaagaac atatggatca tgcagatgct ttactccgtt ggctgaaatc ctatgaacca
    16321 gaaaaattat ttgatgcaca aggacgtatt ttagaagaaa tcagagaaat cgcgcctact
    16381 ggtgaccaaa gaatggcaaa aaatcctatc accaatggtg gaatcgatcc aagaccgctt
    16441 attatgccag attggaaaaa atatactttg caatttgaaa aaccaggctc cgttaaagca
    16501 gaagatatga ccgaacttgg taaattcgtt cgcgagatca ttgagaaaaa tccagaaaat
    16561 ttccgtatat ttggaccaga tgaaacaaaa tcaaaccgat tgaatcaagt tttcaaaacg
    16621 acaaatcgcc aatggatgga aaaaatcgaa ccagaaaatg atgaatggct ttcgccatct
    16681 ggtcgcgtca tcgacagtca attatcggaa caccaagatg aagggttctt agaagggtac
    16741 gttctgactg gacggcatgg ttttttgcaa gttacgaatc attcttgcga gtggttgact
    16801 ctatgttgac tcagcacttc aaatggatgc ggaaatcaca tgacctttct tggcgaaatg
    16861 attatccttc gctaaatctc attgcaagct caacagtctt ccagcaagat cacaatggat
    16921 atagccacca agatccagga atattgacac atttggcaga aaagaaggcg gagttcatcc
    16981 gtgaatatct gcctgcggat gcaaatacat tgctcgcagt catggataaa gcattccgct
    17041 cgtcagaaaa aatcaatttg atcatctctt ccaaacatcc gcgtgctcaa ttttactcag
    17101 cagaagaagc agccgtctta gtgaatgaag gcttgaaaat cattgattgg gcttcgacag
    17161 caaaagagga ggaacctgaa ttggtcattg ctgctgcagg aacggaatct aacttagaag
    17221 cattagcagc tgtaactttg ctgctggaag aattcccaaa actaaaaatt cggttcatca
    17281 atgtcgtaga tttattgaaa ttacgtcatc caagtcaaga tccgcgtggg ttgagcgatg
    17341 aagaatttga tcaatatttt acaaaagaca aaccgatctt atttgctttc cacggttatg
    17401 aaacattggt ccgcacgatt ttctttgatc gtcataacca tcatttaatg attcatggct
    17461 acaaagaaaa tggagatatc acgacaccat ttgacatgcg tgtagtaaat gaacttgatc
    17521 gttatcattt ggcaaaagac gcagctttaa aaatcaaagg aagtcaagca gaagattttg
    17581 cgaaaaaaat ggatcagaaa ttacaagaac atcaaaacta tattcgtgaa aatggtattg
    17641 atctgccaga agtattggat tggaaatgga aaaatcttga ccaataaaat gataaaatcg
    17701 atcccgcaaa atagaatttt ttacattgat taagaaactg aaaaaataaa taaaaaaaac
    17761 ggaaaaaaga ctggaagaat ggccagtctt ttttttcgtt tttgggaagt gaaaaccaaa
    17821 ctatttacct gtaagccacc cataaatcca atcaaatggt gcaaagaaaa aatcttccat
    17881 tctattccct cctttaaaaa agcataacat gatttctatt tacgtgagca tgaattttgt
    17941 tacgttttta ttgccgaaaa ataaaaaccg ttcattatga tgtcaaattc gtcagtaatt
    18001 gatgcaatgt gttataataa ttcagttaaa tcaaaaatga aatggagaaa agacatggac
    18061 gggttattac ctttatggaa agaacgcgga atgacaagtc atgattgcgt attcaaatta
    18121 agaaaaatct tacatacgaa aaaaatcgga catgggggta cgcttgaccc agacgtagac
    18181 ggtgtgttgc ccatttgtat tggaaaagcc acaaaagtta tcgaatattt gacagattct
    18241 gggaaaatct atgtaggcga gataactcta ggtttcagta caacgacgga agatcgatcc
    18301 ggagaacggg tagaaacaaa accagtagat atgtctttat ctgaaaaaaa aatagatgaa
    18361 gtgatggctt catttattgg tgagatcacc cagataccac caatgtactc agcggtaaaa
    18421 gtcaacggta agcggttata tgaatatgcc cgcaataatg aaacagtgga gcgtcctgtt
    18481 agaaaggctc agatttaccg ttttatccgg acaagtgaat tgacaagaga cgaagtgaca
    18541 ggaaccattt cttggcgctt cgaagtagaa tgcgggaaag gaacctatgt ccgcacatta
    18601 gctgtagata caggcaagaa acttggttac cctgcgcaca tgtctgatct gacccgaaca
    18661 gcaagtgccg gtatgtccca gaaggatgct ctgacattag aagaagtagc tcaagctgtg
    18721 aaaaatggga caatcgatga ttgtttgctg ccaatagaaa aaggagtgga acggttcaaa
    18781 cgagtagata ttactgatga agtatggcag aaagtaaaaa acggtatgag acttgattat
    18841 actgtatttg cgctcccaga aatgccgtca gaagaaattg ctttgtttta taaaggaaaa
    18901 gttgtcagta tttatcagcc aaacccgaaa gaaaaaaaca aattaaaacc tagtaaagta
    18961 ttgagaaatg aggaataacg aatgaatatc atcaagatca gacatcctta ccaatcagaa
    19021 caaattccag aagacgatgt cgttttagtg ctgggatttt tcgacggcgt gcatatcgga
    19081 caccagaaag tcataaagac aggtatggaa attgcacaaa aagaaggatt gaaattagca
    19141 ttgatgactt tcaatcagca tccatctatt gtctttaaaa agatcgatcc tagcagcgtg
    19201 aaatatttga ctagccttaa gcaaaaagaa gaaaaaatgg ccgctttggg tatagattat
    19261 ttatatgaag ttgattttac ttcttctttt gctcatttag caccgcagga atttgttgat
    19321 caatacatcg tagggttaca tgcaaaatat gctgtttccg gttttgatta tacgtatgga
    19381 ccaaaagaca ttgcagatgt cgctcatttt cctgaatatg ccaaaggaag attcaaaatc
    19441 gtcacagttt ctaaagaaga agaacaaggt gaaaaaatca gctctacccg tattcgtgga
    19501 ttactagaca gcggacaagt aaaagaagca gcaaaactat taggttgcac atatgaggta
    19561 gaaggggtag ttgtccatgg cgatgcacga ggcagactac taggattccc tacagcaaat
    19621 gtcaaagtaa agagcacggt tcatttgcct aaagaaggtg tttatgtgtc ggaaataaaa
    19681 attggggaaa catggtatcc agccatgggt tcaattggac ataatgatac attcggtgaa
    19741 ggacgggagc tgactgtaga gttgtatatt ttggacttta atcaagatat ctatggtgaa
    19801 catgtcgcgg tacgctggaa tcaattttta agagatcaag tgaaattttc tagtgtagag
    19861 gaattgattg aacaactcaa ggaggatgaa caagcaacag ctgaatattt ttctcagcaa
    19921 taaaacatta tgcataaaat ctcttgttta tgtataacta gcaattacaa taaaatgggt
    19981 gataaataag cccag
//
LOCUS       DAFLVO010000055        19633 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.055, whole genome shotgun sequence.
ACCESSION   DAFLVO010000055 DAFLVO010000000
VERSION     DAFLVO010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19633
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.055"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="L1U99_002005"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="L1U99_002005"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HBN1212540.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="L1U99_002006"
     CDS             complement(1172..1867)
                     /locus_tag="L1U99_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBN1212541.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="L1U99_002007"
     CDS             complement(1880..2596)
                     /locus_tag="L1U99_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HBN1212542.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3534
                     /locus_tag="L1U99_002008"
     CDS             2926..3534
                     /locus_tag="L1U99_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HBN1212543.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            3859..4182
                     /locus_tag="L1U99_002009"
     CDS             3859..4182
                     /locus_tag="L1U99_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBN1212544.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4364..5734
                     /locus_tag="L1U99_002010"
     CDS             4364..5734
                     /locus_tag="L1U99_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBN1212545.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5864..7165)
                     /locus_tag="L1U99_002011"
     CDS             complement(5864..7165)
                     /locus_tag="L1U99_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBN1212546.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(7519..9477)
                     /locus_tag="L1U99_002012"
     CDS             complement(7519..9477)
                     /locus_tag="L1U99_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HBN1212547.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9654..9920)
                     /locus_tag="L1U99_002013"
     CDS             complement(9654..9920)
                     /locus_tag="L1U99_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBN1212548.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10430..12556)
                     /gene="pnp"
                     /locus_tag="L1U99_002014"
     CDS             complement(10430..12556)
                     /gene="pnp"
                     /locus_tag="L1U99_002014"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBN1212549.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12744..13013)
                     /gene="rpsO"
                     /locus_tag="L1U99_002015"
     CDS             complement(12744..13013)
                     /gene="rpsO"
                     /locus_tag="L1U99_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBN1212550.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13264..13827
                     /locus_tag="L1U99_002016"
     CDS             13264..13827
                     /locus_tag="L1U99_002016"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBN1212551.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(14080..14601)
                     /locus_tag="L1U99_002017"
     CDS             complement(14080..14601)
                     /locus_tag="L1U99_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBN1212552.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14604..15446)
                     /locus_tag="L1U99_002018"
     CDS             complement(14604..15446)
                     /locus_tag="L1U99_002018"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HBN1212553.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15439..16164)
                     /locus_tag="L1U99_002019"
     CDS             complement(15439..16164)
                     /locus_tag="L1U99_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBN1212554.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16340..16636
                     /locus_tag="L1U99_002020"
     CDS             16340..16636
                     /locus_tag="L1U99_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212555.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17204..18796
                     /locus_tag="L1U99_002021"
     CDS             17204..18796
                     /locus_tag="L1U99_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBN1212556.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18809..19549
                     /locus_tag="L1U99_002022"
     CDS             18809..19549
                     /locus_tag="L1U99_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBN1212557.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5620 a         4028 c         3724 g         6261 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcaaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 gaaagcacag gtgaaggtgg cgaaccagaa gtgatcggtt caacagaaga ataatactga
     3541 aacaatcagg tggtgttaga agcggcgggt cagcagcttt taacacgcct tttttatttc
     3601 taatcgttta ttttcatatg gggcttccac ttttgtaaat ggctttacaa acgaaaaatc
     3661 ctaatttacc aagcttttcc tcgcatactt ttatcgtacc tttataaaaa tttatacttt
     3721 gaaaaaaagt attcaattat tgttgcattt ttcctgattc tttattagaa tgaaccctcg
     3781 ttgaagtaag tatttctagt ttatcctagg attaattata aaaataaaac attcgttgat
     3841 tcgaaggagg ttaaacagat gtttgaaagt tttgatagca gccgcaaccg ttacgcttca
     3901 gttggtgtcg tatcaagttt gccagatgaa ttgattgaca gtatatggtt tattattgac
     3961 ctagatctta agggagtcat tccattagaa aatatattaa cctttgattt gatcgaaaat
     4021 cgtggaaaag tgacgatgca tttttctcaa gcaggaagca atgtggaaat ggatattgat
     4081 ttgccgtttg cctattcgaa ccaatttcct gctcaagtat acgcctatga tgacggtacg
     4141 agagaaacga tccttttacc aagtgagatt agacaatatt aaggtgatag ataaacgtgg
     4201 atgtccctta ttttacagac caggccaagt tgttgattct ttgactcaat tcttggcttc
     4261 tttttatgga gtttcataaa ttatcattga tttctaattg gtattctcag gataaacgct
     4321 atatactact aactaaattt taaagatata aggagtttaa aagatgcgcg atttaacaaa
     4381 aggaagcccc gctaaactga ttttgatgtt cactgttcct ttactgatcg gaaatgtttt
     4441 tcagcagttc tacaatatga tcgatatgat catcgtgggt cagacgctag gtaaaaatgc
     4501 gctggcagcg gttggtgcaa ctggaagcct gacatttttg atcattggct ttgcccaagg
     4561 tttaacagct ggtttagcca ttattaccgc acaacgttac ggtgcaaaag attatcgggg
     4621 tctgaagaaa agttttgctg ctagtgttgt cattagtctt gtcgtcactg tgattttaac
     4681 tgtcctaagt ctcctgttta ttcgtccgat gcttcaattg atgcaaactc ctcctgaaat
     4741 acttgatcaa gcacaaacat ttatttcaat tattttatta gggatctttg catcagtcag
     4801 tttcaatttg ctttctaatg tcattcgcgc acttggtgac agccgcacac cactattctt
     4861 tctgatcatt gcggtcatca tcaacgtcgt acttgatttg atctttatta tctattttgg
     4921 catgggtgtg gaaggtgcag ctattgctac agtaatcgca caagtttctt ccagcgtact
     4981 gtgtctagtg tatatcaaga aaaaaatgcc tttgttacag ttacgcaaaa aagatttcaa
     5041 atttgaaaaa gaagagtttg ctgtacacct aaatgctgct ttgccaatgg cgtttcaatc
     5101 ttcgatcatc gctgttggtg ctatcgtgtt acaagcagca ctaaatagtc tagggacaga
     5161 tgtcgtagct gctcaagccg ctgctggtcg tatcgaccaa tttgcaaatc agccgatgat
     5221 gtcatttggt attgcaatgg caactttcac tgcacaaaac tatggtgcga aagaatatgg
     5281 ccgaatcttg caaggggtac gtcaaacttt actgatgagt gtcggattta gtctcttagc
     5341 aggtgctatc gtcattttct tcggtcattt ctttgttcaa ttgtttgtta gcccatcaga
     5401 aacacgtgta tttgaattag cacaaaccta cttcaatatc aatgggtctc tttactggat
     5461 cttagcagtc ctgttcattt tacgctacac acttcaaggg cttggacaaa gcaagatccc
     5521 tacgatcgcc ggtatgatgg aattgcttat gcgttctttt gcagctatcg ttcttacagg
     5581 aatgtgggga tacccaggag cagcagcagc ttctccttta gcttggatcg gttctgttgc
     5641 cgtgttgctt tactcttata tgcgttcgat gaaacaattg aaacacatgg gtgaagagga
     5701 acatttcaca ttagaacatg cagaagcaag atagccttga ttaaaagaaa tcgttgcggc
     5761 taaaaatgaa aacttttatt gaaaatatct tcttcgttta ccgaaaacag gttttttaga
     5821 taacaaaaag gctgtgacaa aaaatgtcac agcctttttt cttttattct gtttttcttt
     5881 ccgtggactc tactttgaaa taatcgatat gtgcatgctg gtattctaat accgtgaaac
     5941 ggaatgatgc aatctcaatg attgttcctg cttttatttc tttatatcgg ctagaagcaa
     6001 agcccgcaag tgtagtaaaa ttcgtttctt caaactctgg aatctctaca tgaaaataac
     6061 gctggaaatc atctaatgtt agtttgccgg agatgatata agagccatct gactgttccg
     6121 ctatcaatgc ttcgtccaaa tctgtctcat ctcggatttc cccgacgatt tcttctaaaa
     6181 tatcttcaat cgtcactaag ccgcttgtcc ctccgtattc atcttttaag atagcaatat
     6241 gcttaccctt ttttcgcatg atcgtcaata atttttttat agggatcgtt tcagttgtta
     6301 cgatcggctc ttcaatcaac tgttctactg tcagctggtc atctttataa gattgcttga
     6361 tcaaatctgg caaggtgaca taacctaaaa cattgtcttt tgattctaag ataaccggat
     6421 agcgagtatg tccttgttca atcgaagctt ttatcgcttc tttgacggtt tctgaagctt
     6481 cgaatacttg catggacgta cggtctactt gtatatcttt tgccaaggta tcatcaaatt
     6541 caaacacgtt ttccaaataa taatattctt ctttggtcaa ctctcctttt tcataagaat
     6601 tcaatgcgac taatgtcagc tcttcttgag acaatgtctc ttctccttca gatacgagac
     6661 gcacacctaa tagcttccct agccctgcag ctgaatgatt caatacccaa ataaaaggaa
     6721 acattacttt ataaaaataa tgaagtggtt taactacgaa caagacgacc ttctccgtat
     6781 tgacgatact atagctctta ggaagcagtt cgccaataac cacatcgata tacgtaacta
     6841 aaataaatcc cagcgccaca gagattgtac tgctaatagc cgaactaaaa ggtagtttac
     6901 cgatcactgg ttctagtaaa gccgcgacag atccttcacc gacccacccg atgatcaaac
     6961 cggttagcgt aattcctaat tgactagctg ataaatagtt atctaaatgg tgtgtaacat
     7021 gaagagctag cttggcgttc tttacatttt ccttttctag ttgttccaat cttgatcgtc
     7081 tgattttcac taaagcaaat tcacttgcta caaaaaatga agtaattgca atcatcaaaa
     7141 ataaaataat gaaattgata accatattct cccgcctttc tctttttcta ttgtaccctt
     7201 tttctacaaa aagattgaaa ataatgcgta ttcatattta ggaataaaaa aggagatgcg
     7261 gcatttttca gccacatctc cttatcactt caaaatcatt gcgttacttg ttgctaaaca
     7321 gctttttcat gacctctgat aaaaacggta ttcaaaagct tgcatctacg gcattaagcc
     7381 caaacagatg aaaaacatga gaagctgttt ttatctgctc gttcttactg cttgttgcag
     7441 tacagctttt tcatgacctc tgataaacgg tgttcaagta gctgacattc gacattagtt
     7501 caggtcaaag cgctactttc acaaccgctc tttcaaccat gttttccgag tatttccaat
     7561 gataagcgga acagtttcat gttttacttc gctgtactct agcccaaacc atgtttctgg
     7621 cgaggtagcg atttttttga ttgccagttt tgcctgcatg atttgacgtt gccattttcc
     7681 tagagttgtc acattggaaa ctacttcatc aatcaggaca aattggaaat cgccaacttc
     7741 tcgccctggt gtcagagagt atctttgtgg ctgttttggc aaacggcctt gtttcatcaa
     7801 atcatggatg acttggcgaa catatacgtt gatttcctgt tggaccctga aacctaagaa
     7861 cagattcact tggacaataa aatcagtgtc catcatatct acttgatatt ctttcgtata
     7921 tggctcatcc gtcacttcca catgaacaaa ccaatagact cgtgctcttt taggccgttt
     7981 atctaaaatc gaatagatga actgtcggcc aactttatct tcagccatat caggaaccaa
     8041 gaagaccaca tttgtctgat agattggtaa agaagtatca tcacgtaatt ctctaagctg
     8101 cgggatataa tctctcaaag acacatcctc ggttgacgat tcgcgaataa tgttcccttg
     8161 ttcccaaata aacatcacga ctaagatgat caaaccaatc agaacggcta caaaaccgcc
     8221 tcggaagaat ttgacaacac ttgagataaa gaaaacgact tctatcgcac cgaagaaaaa
     8281 ggtaactaaa tatgcaagcc aacgagaatg cccattttgg ataagataaa agtaaagcag
     8341 tgctgttgtc atcaacatcg tcacagtgat cgatagaccg taagcagctt ccatatgatg
     8401 agacgttcgg aatgtgacaa ccactagaga acaggcgatc cataaaatca gattgactgc
     8461 tgggatatac atttgcccga tactgttccc aggatacatg atctttaacc gaggcagcag
     8521 tttcaacttg attgcttctg aaactagcgt aaacgaacct gtaatcaatg cttgcgaagc
     8581 aatgactgca gcgactgttg caaaagcaac gccgatcacg atccaacttt gaggcatcat
     8641 ttggaagaat ggattcaggt tcttgatttg ctgtgcttca gggttttgat aaacattcaa
     8701 caaccacgca gcctgcccaa aataattgat aaccaaacaa attttgacgt aaggccagct
     8761 cagacgaata tttcgtttgc cgacatgtcc aagatcggaa taaagcgcct ctgcacctgt
     8821 cgtagccagg aaaatatttc caagaatgaa caagcctaat ttgttatctg cactaaaaag
     8881 cagctggata gcataataag gattcagtgc acggataact gtccagtctt gactgaagtt
     8941 cattaatccc attacgccta aaaaagtaaa ccaagcgaac atgattggtc cgaatgcttt
     9001 tccgacaata tctgtaccaa agcgttggac catgaataaa acaaaaataa taactaaagt
     9061 gataatgacg atcacgttct ggttattacc gaaccggtca aaaaactgcg gaattcctcg
     9121 caagccttca atcgcagtcg ttaccgtcac agcaggggtc aataccccat ctgctagtaa
     9181 ggcagctcct ccgatcattg caggaatgat caaatatttc ccaccttttc ggacaagtgt
     9241 gtagagtgag aaaattccac cttcaccatg gttatctgca ttcaatgcaa tcacgacata
     9301 tttgattgtt gtcagtagag tcaatgtcca aaaaatcaat gagactgatc cgataacaaa
     9361 atcaggattg attcctgaca atccgccatt atcttcaaca atcgatttca taacgtaaag
     9421 cggacttgtc ccgatgtctc cgtagacgac tcccatcgct acaagcaggc cagccattga
     9481 tatctttttg gtattgtgcg ttgttgccac gtttttccct catttcttgt tatatggata
     9541 tcctttaggt aagcttgaat gatagatgat attcttatcc atgacacccg ctttcctaaa
     9601 ttgcttctaa ttatccaagt aacacactga agtgtcaact tatttgaata aaattattct
     9661 ttctttggac gttctctgat acgtcttgcc acaaatgaat aaagagcaag gcaaaaaatt
     9721 gcacccaata atgctggtat caaataaaaa ccgccgagtt ccggtcccag tggtcctagt
     9781 aaaaattcgc cgagccaact acctaaaaaa ccgataatga tatttccaga tacgcctccc
     9841 gggacttcct ttcctaaaat tgcgccagct atcaaaccta atataccgcc gataaataac
     9901 gaccataaaa aattcagcat ctcctttccc tcctttatcc atatttctca cttttatttt
     9961 acgctttatt cagaaggact ccaaaaatat gcgccaagaa actccagaaa aaaagaagtt
    10021 gtaacaaaag tgttcagctt atttccgtag aagctgcttc tggaacaccg tgaatcagag
    10081 gttgtgaaat cagcggtttg acctgagtat tagagaaaca aacggaaaaa tagttcctca
    10141 tattttgccg ttttttgagc taatatcgag ggacagctga ttgaacatcg tttattggag
    10201 aggttgtaaa aaagctgttc tgcatcaagt aataagaaca gccaagtaaa aacagctcct
    10261 aatgttttta acttggctgg acttattacc gcagatgcaa gcttttgaac accgtttatt
    10321 cgaaaaaaaa ggactgtgac acggcttttg tcacagtccc cttttttcga ataattattg
    10381 tccccctgtc accttcacga tcacaagtac attattccta tgaattaaat tatttttctt
    10441 catttttcgt tgaaccatct tcgttcaaca ttgcttttct tgacagattt acgcgtcctt
    10501 gtttatcgat ttcagttact ttcacaagga tctcatcacc tagtttaaca acatcttcga
    10561 ctttattgac acgatcgttt gctaattggg aaatatggac aagtccatct tttcctttga
    10621 tcaagttgac gaatgcaccg aatttttcga tacggacaac tttccctaga taaacttcac
    10681 caactttgac ttctttggtc aaatcttcga tgatcttgat agcttttttg atcatttctg
    10741 catcagctga agcaatactt acttttccat cttgatcgat atcgattttc acaccagttt
    10801 catcgatgat tccgttgatc gtatcgccgc ctttaccgat aacatctttg attttagcag
    10861 gttcgatctg gatcatttcg atttttggtg catattggct taattcttca cgtggagcag
    10921 caatcgttga agtcaattct tctaagattt ccatacgtgc ttgttttgct tgagttaatg
    10981 cttcagttag gatttgttct gtgattcctt gaatcttgat atccatctgt aaagcagtga
    11041 taccatcttt tgtaccggca actttaaagt ccatatcgcc aagatgatct tccagccctt
    11101 ggatatcagt taggatcgta tagttttcac catcagaaac aagtcccatc gcaataccgg
    11161 cgactggcgc tttgattggt acacctgcat ccatcaatgc taatgtgcca gcacagatac
    11221 ttgcttggga agaagaacca tttgattcca atacttctgc tactaaacgg atcgtataag
    11281 gaaattcttc ttctgaaggg attacttgtg ctaacgcacg ttcacctaat gcgccatgtc
    11341 cgatttcccg acgccctgga gagcctgcac gtcctgtaga accaacagaa aattgaggga
    11401 aattgtagtg gtggatgaat cgtttgctga cttccacccc taaaccatca atgatttggt
    11461 gctctcctag aggtgcgagt gtacaagctg ataaagcttg tgtttgtcct cgtgtgaaca
    11521 aacctgatcc atgtacacgt ggcaataagc tgacctctga tgacaatgga cggatttcat
    11581 ccaatttacg cccgtcagga cggatcttat cgatggtgat caattcacgt acgacatctt
    11641 tttcaagatc ttctgtgatt tgtttaactt ctttcaacaa gtgatcttca tcttcatgac
    11701 ctgcaaattt ctcagcataa gcttcgcgga tatcgatctt cacctgctcg atattatctt
    11761 cgcgagcaag tttttcttca gtcattactg ctgctttcat tgtagcgtaa gaagcatcaa
    11821 agatttcttt tttcaatact tcatcaactt gcagtaaagt cacttccatt ttttctttcc
    11881 ctactgcttg aacgatttct tcttggaaag caactaactc tttgatagcg tcaaaaccaa
    11941 acagcaatgc accaagcatg tcttcttctg aaacttcttt cgcgccgctt tcaaccatat
    12001 tgatggcttg tttcgttccg gcaacagtca attcgatatc tgtttgttct gcttgttcta
    12061 ctgttggatt caagacgtac tcgccattta cacgaccaac ttctacgcct gcgattgggc
    12121 cgtcaaatgg gatatctgag attgatagtg ctaaagaaga acctagcatt gctgccatag
    12181 ctggcgagca gtctgtttct acactcatca cgatgttcgt tacttggact tcattacgga
    12241 agccttctgc aaacatcggg cgaattggac ggtcgatcaa acgggcagtc aatgttgctt
    12301 ccgtacttgg acggccttct cgtttgatga aacctccagg gattttccct gctgcataca
    12361 ttttttcttc ataattgatc gttaatggga aaaagtctgt atcttttgct tctttagagg
    12421 ccacagctgc acttaagact actgtatctc cataacggac taaaacggct ccgtttgctt
    12481 gttttgctag ctgaccgact tcgatttgta agggacggcc gccccatgtc gttttgaata
    12541 cttgtttttc tgacataact tctccttttc cttctcgtga aagcaagacg ctactaaaca
    12601 aatgaaaact gccgaaagcc gtcttttgag cagctttcat ttggttagta ggagtccatc
    12661 tagcttgatc acggaatttt acttaattga tatacgagta aaaaaagtga gattcatgtg
    12721 aatcccactc tttttgacta aaattaacga cgcaagccta aacgtttgat caattcgcgg
    12781 taacgttgaa cgtcagtttt acgtaagtaa gctaacaagt tacggcggtg accaactttt
    12841 ttcattaggc cgcggtatga atgatggtct tttttgtgca cgcgtgcatg ttcattcaag
    12901 tggttgattt cttcagttaa tacagcgatt tgtacttctg gagaaccagt atccccttca
    12961 tggcgagcgt attcgttgat gatttcattc ttgcgttctt ttgaaattgc catttctttc
    13021 acctctttcg attattcccc tgcgactgag taaaacgttg gtgattcgct taaccaagtg
    13081 gcaggtcatg tgcctagagc acacagctat actttacctg aaaccgggtt gaaaatcaag
    13141 tagttaatca ttaagaaaag gtagttttca aacaatctta ctactacttt tccatttttg
    13201 tggtaaacta taatgcgaaa atagacttga aacacagtct tttaagaaag gggtacatat
    13261 tccatgatta caatggatga tatcattcgt gaaggaaatc cgaccttacg cgaagttgca
    13321 aaagaagttt ctcttccatt aagcgaagaa gatatctctt taggaaaaga gatgcttgag
    13381 ttcttaaaaa acagccaaga tccaatcaaa gctgaagaac tacacttacg aggcggtgtt
    13441 ggcttagctg ctcctcaatt agatatttct aaaagaatca ttgctgttca cgtaccaagt
    13501 cctgacccag aggcagatgg accttctcta agtactgtta tgtataatcc taaaattttg
    13561 agccattctg ttcaagatgc ttgtttaggg gaaggtgaag gctgtttatc tgttgatcga
    13621 gaagtaccag gatatgttgt tcgccatgcc aaaatcactg tgtcttatta tgatatgaat
    13681 ggtgaaaaac acaagattcg tttgaagaat tatgaatcga tcgtcgttca acatgaaatc
    13741 gaccatatca acggtgtgat gttctatgac cacatcaacg atcaaaatcc atttgcacta
    13801 aaagaaggcg tattggtgat cgagtagaga attggcaggt tccttcgata ctatgctaca
    13861 agaaagcttt ataaaaaagg ggagtgctca aaagctgcac ttcccttttt tatgtttctc
    13921 cactaatcga aatttagata gacatctaga aatcgcaatt ccaaaaaatt ctgtgtattg
    13981 gatacgcatc ttttcttatt ttttcttatt tcttccatat gggtgtttat ctcagagatg
    14041 atagaatagt ttctaggata aaaagtagca gctacgatgt tatccttcgt agaggattcc
    14101 tgcttcagct agtttttgtt tgatgttttt cagcatatgc ttttctgggt agcggatcgt
    14161 atgcagatgg atgccgcctg ttaattcgga taacaaagta gcattacttt tttgataacg
    14221 tctcataaag gaatcgatat cttgtggcgt tttgatgtgc aaagttcctg ctaactcacc
    14281 gtaaagggga tgttccacaa ttacatcaat gatttcacca ccattttcaa cgattagtct
    14341 cagttcttct tctgtttgat cttttccatg ctggacagcg attttactga tgtgcccagt
    14401 attggtttct tctgtttcga ggatataacc tcttgctgtt gccacgatac ttttacctgc
    14461 agctcgtagt aaagcaatat cgcctacaat gatctgacgg ctgactccaa aagttttcgc
    14521 aaacttgcta gcactcactg gtttttctgt atttgccaag gtttgcatga tttgttttcg
    14581 ccgtgtctct ccttcgatca cacttattcc tccttcattt tgttttggta ttcgcgcgag
    14641 tgtttcatca aatcaacata cgtgtctgtt attgtttcct tatatccctt atttttcagc
    14701 agactaacaa ctttatccaa tacttgctgc tctctttttg catcataaac tgcttggttt
    14761 tcttcttttt tcacttgtcc tattttagtt accgtatcca ttcttttttc taataaagca
    14821 accaactctc gatcgatcat atcgatctta tgacgtaatg tttcaagaga ctcttctgtt
    14881 agttcttcct ctactgtctt gatgatacga gcaggatttc ctgcaatcac tacattgtcg
    14941 ggaaaagatt tggtcacaac cgaacctgcg ccgactacta cgttgtcccc tagagtgaca
    15001 cccggcgtga cgataactcc tccgcctaac caaacattat taccgatttt aatgggtttt
    15061 gcgtactcca gaccgctgtt acgtttcact ggatgtagtg gatgcgtcgc cgtgtaaagc
    15121 tggacattcg gagcgaacat gcagttatca ccgatttcaa tcgtgctgac atctaaaaat
    15181 gtacaattga aatttgcata aaaattctcc ccaacaaata tattatatcc gtaatcaaaa
    15241 ttgataactg gctccatata gatttttttc cctgtacggc caaaagtctc tttcaacaat
    15301 tgggatcgca gttccgctga ttctgcttgg ttgatgattt ggctttgact tcttgcaaac
    15361 atacggtcgg caaccagctc aggatcattg gcaaaataaa gctcgcctgc aatcattttt
    15421 tctttttcgg ttttgaattc agtcataatc tgctcctaat tcttgtattt ttttgaaaac
    15481 aaccgctccg tcttcttgaa taaacgtata aggctccgct aaataaacag gcgtttgatt
    15541 gattactaag attttggctg acggctggcg aaactgtacc agatcacaaa acggatgaac
    15601 ttgaaaactc gttccaacaa tgacgatcag ctctgcttgg ctgacggcat aagccgcctg
    15661 ctccatgact ccatcttgaa acccttcacc atataacacg atgtctgggc gtatttgtcc
    15721 tccgcatgct tgatgtttgt cgctgtgaag atattctttc cagtctaccg tttgttgaca
    15781 ttttcgacaa tgacattgat acagactccc atgaaaattg acgagttgcg ggcttttagc
    15841 ctttgcgtgc aaaccgtcga tgttttggga aacaacccaa acattttttt ctttcgctag
    15901 atgtgctatt tccaaatgaa tgatattggg ttttgcttca ggatgataaa tctttttgac
    15961 aaattgatag aatttatccg gttcattcac cattgcttga tgactcagca agtattccgg
    16021 ctgctccatc ccgtggtaga ttcctgacaa agatcgatag tctggcactc cagaaggtgt
    16081 ggatacccct gcaccggtca aaaatgtaat ttgctgataa gctaatatct cttttgctgc
    16141 ttcgtctact gttaattgtt tcatgttttg tcacctcact ttccattata gcccatactc
    16201 gaacaaattt attgttgaaa agtcagaaaa atgggaataa aaaagtgtta tgggcatttg
    16261 agcaatttat cacaatgttc actgacaaaa gaatgaaaac gtgttacaat actgctgtat
    16321 aaaagtgagg tgaatcgata tgttaccatt ctttatttat tggggcgtta ttctggcttg
    16381 tatcgcctgg ttagcgttaa gcgtttattt ctctgttttt tatcttgtac gcaaagaaaa
    16441 tggaaatctt tgggcttttg ctttattcaa cgtgattgcc gcaattgttt tagccattac
    16501 attagccgta tatcgaacat ggggctgggg aatcacccaa tactcaagtt tgatttatct
    16561 aatattagcc atttatggcg tcgttgttct tttgcaagcg atcctaggac gtgagccaaa
    16621 gaaagcggca gcttaaatga tcgagatgga actggacaca ggaaattttc tgttctagtt
    16681 ctttttttat tgtattacat acatttttgt gtataattat actatcgttt gcaatggata
    16741 gatgattcac attttgattg ttttttcggt aaaagtaaag atttctatat ttatcagtat
    16801 tttttcaaaa accagcagtt atagattgac aaagcctctc gagtatcgta aacttttttt
    16861 gtataaataa ctgaatacga gatgcctcaa tcaatgaggt agaggtcgcg agaatcatta
    16921 accctgtgga gtgaagcaaa catggagaag caggaatagg gaggatcgcc gaaatgtgca
    16981 cttttttgct tggagtgtat gttgggacgc aagttaagag cttgcggact gtcttagcag
    17041 tgatgctaag ttgcgctatg ttttgtgaga ggtttatcac cttatggaat tttagcggcc
    17101 tttttatatc tataaatcgg tcgcttttta ttttttcaga taaagcttta ccgcatttca
    17161 tctagaccgc tcgtgtatca tataatcaga aagggagaaa aaaatgaaaa aaaatatggt
    17221 ttcagttgcc gtactatttg cttttgtctt ctcactattc agtgtgggat ctctggcaaa
    17281 tgcagatgaa aaaacaccga gcgatgagtt tcgcgtaggt atggaggctg ggtatgcacc
    17341 cttcaactgg tctcaacaaa cagatgagaa taatgccttg ccaattcaag gccaaaatag
    17401 ttacgccggc ggttatgatg ttcaaatcgc taaaaaagta gcagatggtt tagggaaaaa
    17461 attagtcatc gtccaaacga aatgggatgg tctggctcct gcccttcaat caggcaagat
    17521 cgacgcgatc atcgccggaa tgagccctac tgctgaacga cgaaaagaaa ttgattttac
    17581 cgatccttat tacgaatcac aattagtagt agtagttcaa aaagatagca aatatgcaaa
    17641 agcaaaaagt ttagcagatc tttctggagc aaagatcact gctcagttaa atacattcca
    17701 ctatactgtg atcgatcaga taccagatgt gcagaaacaa caagcaatgg ataatttctc
    17761 agcaatgaga acagctttag cttctggaat gatcgatggt tatgtcagcg aacgtccgga
    17821 aggtgtaacg gcaactagtg tgaacaaaga cttggaaatg cttgaattca gcggtgcaga
    17881 tggcttccag acaaacccgg aagatgttca gatttctgtt ggtatgcgta aaggcgaccc
    17941 ggatatccaa aaagtaaacc agattctttc tggcatctct aacgatgaac gaaccaaaat
    18001 tatggaccaa gcagtcaaag atcagcctgc tgcaactgat agtgaagaaa aacctggcat
    18061 catttctgat ttcactacga tttggaaaca atacggcaat atgttcttac gaggtgctgg
    18121 acttaccttg ttcatcgcat tgatcgggac agttgtcggt actacacttg gattactgat
    18181 tggtgtcttc cgttcggtac ctgaatcagg aaatgcactg actcgcttct tccaaaaaat
    18241 cggaaatgca cttctttcta tctatgtcga agtattccgc ggaacaccga tgatggtaca
    18301 agcaatggtc atcttctacg gtctggcact cgcttttggc atttcattga accgaacgat
    18361 tgccgctttg tttattgtct ctctcaatac tggagcttac atgacagaga tcgttcgtgg
    18421 ggggattttt gcagtagatg aagggcagtt cgaagctgcg caagccattg gtatgaccca
    18481 tggccaaacg atgagaaaag ttgttattcc acaagtttta cggaatatct tgccagcaac
    18541 aggaaatgag tttgttatca atatcaaaga tacagcagtt ttaagtgtaa tcggcgtagc
    18601 tgatttgttc ttccaaggaa actctgcttc cggtgcgaat ttccaattct tccaaacatt
    18661 tacgatcgtc gggatcatct acttagtcat gacctttacg atcaccagaa tcctgcgggc
    18721 ggtagaaaag aaaatcgatg gtccttcagc ttataccaag cttgaagaaa tcgacaattc
    18781 aaatttgcag gaataaggag gaagaatcat gaatgaaaaa attattgaaa tcaaacatct
    18841 aagaaaaagc ttcggtgaaa atgaagtatt gaaagatatc agcgtaacag tcaataaagg
    18901 tgaagttgtg acgatcatcg gttcttccgg ttctggtaaa tctactttct tgcgctgtat
    18961 caatttactg gaaaaaccaa caggcggcga gatcatttat aatggagaaa atgtattagc
    19021 tcctaaatat aatttaccta aatatcgaac gaatctaggt atggttttcc aatccttcaa
    19081 cctgttcaac aatatgaatg tcttggaaaa ctgtatgtct ggtcaaacaa ctgtcctgaa
    19141 acgagataaa gaaactgcca aaaaagtagc aatcgaaaat ctggaaaaag ttggtatgga
    19201 tcgttatatc gaagccaaac cagcacaatt atctggtgga cagaaacagc gtgtcgcaat
    19261 tgctcgggca ttatcaatga atccagatgt attgctattc gacgaaccta cttcggcgtt
    19321 agaccctgaa atggttggcg aagtgcttaa tacgatcaaa gacttagcac atactggctt
    19381 gacaatgctt atcgtgacgc atgagatgga atttgcaaaa gatgtatctg accgtgtcat
    19441 ttttatggat aaaggtgtga ttgcagaaga aggtacacca gaagatatct ttgtccatcc
    19501 gaaagaagaa cgtacaaaag aattcctttc acgtatttta aatgcttagg atcaatagct
    19561 gattgggaca aagagctgcg gtgtttaccg cagttctttt ttatgaatta ctcataaaag
    19621 gtaaatttct gaa
//
LOCUS       DAFLVO010000056        18538 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.056, whole genome shotgun sequence.
ACCESSION   DAFLVO010000056 DAFLVO010000000
VERSION     DAFLVO010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18538
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.056"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            133..780
                     /locus_tag="L1U99_002023"
     CDS             133..780
                     /locus_tag="L1U99_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBN1212558.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKLLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    909..1125
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1173..3818
                     /locus_tag="L1U99_002024"
     CDS             1173..3818
                     /locus_tag="L1U99_002024"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBN1212559.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            4128..5441
                     /locus_tag="L1U99_002025"
     CDS             4128..5441
                     /locus_tag="L1U99_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBN1212560.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            5431..6084
                     /locus_tag="L1U99_002026"
     CDS             5431..6084
                     /locus_tag="L1U99_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBN1212561.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            6139..6831
                     /gene="radC"
                     /locus_tag="L1U99_002027"
     CDS             6139..6831
                     /gene="radC"
                     /locus_tag="L1U99_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBN1212562.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            6981..7181
                     /locus_tag="L1U99_002028"
     CDS             6981..7181
                     /locus_tag="L1U99_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBN1212563.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(7435..9114)
                     /locus_tag="L1U99_002029"
     CDS             complement(7435..9114)
                     /locus_tag="L1U99_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBN1212564.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(9116..9328)
                     /locus_tag="L1U99_002030"
     CDS             complement(9116..9328)
                     /locus_tag="L1U99_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HBN1212565.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9721..11451
                     /gene="efrA"
                     /locus_tag="L1U99_002031"
     CDS             9721..11451
                     /gene="efrA"
                     /locus_tag="L1U99_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HBN1212566.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            11448..13208
                     /gene="efrB"
                     /locus_tag="L1U99_002032"
     CDS             11448..13208
                     /gene="efrB"
                     /locus_tag="L1U99_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HBN1212567.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            13303..13500
                     /locus_tag="L1U99_002033"
     CDS             13303..13500
                     /locus_tag="L1U99_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212568.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            13653..14138
                     /locus_tag="L1U99_002034"
     CDS             13653..14138
                     /locus_tag="L1U99_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBN1212569.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(14242..14835)
                     /gene="clpP"
                     /locus_tag="L1U99_002035"
     CDS             complement(14242..14835)
                     /gene="clpP"
                     /locus_tag="L1U99_002035"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBN1212570.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            15015..15542
                     /locus_tag="L1U99_002036"
     CDS             15015..15542
                     /locus_tag="L1U99_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212571.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            15633..16370
                     /locus_tag="L1U99_002037"
     CDS             15633..16370
                     /locus_tag="L1U99_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBN1212572.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            16374..17291
                     /gene="miaA"
                     /locus_tag="L1U99_002038"
     CDS             16374..17291
                     /gene="miaA"
                     /locus_tag="L1U99_002038"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBN1212573.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            17293..18522
                     /gene="hflX"
                     /locus_tag="L1U99_002039"
     CDS             17293..18522
                     /gene="hflX"
                     /locus_tag="L1U99_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBN1212574.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT         5992 a         3208 c         4028 g         5310 t
ORIGIN      
        1 attaccgcag atgcaagctt ttgaacaccg ttttatttgt ctcacaccct tttccttcct
       61 acttgtaacc ttgctcccgt gttagaaaca tgttacacta aatatgtgaa attattaaca
      121 aggagcgtcg ttatgcgaga aaaaacagat acactgccaa aagcaactgc gaaaagatta
      181 cctttatatt tacgctactt gaagttgctg gatgactcag gtataagtag aatcaaatca
      241 aatgagttca gcgaaatcac ccaaattcct tctgcaacga tccgcagaga cttctcgcaa
      301 ttaggcgagc taggcagaag cggatatggc tatgatgtcc cttttcttat cgatgtattc
      361 aataatatcc ttaatactaa agaagaaaaa cgaatcgcat tagtaggata tggaaatctt
      421 ggcaaagcat tgaaacacaa caattttaga agaaatgaaa atctaaatat cgtgtgcgtc
      481 tttgataatg atccagcact gatcaatcga gtaattgatg gagaaatgat ctatccgatt
      541 gatcgtttcg cggagatagc caaagcaaaa aatgtgacag tagcaatctc tacggtacca
      601 agtaaatatt cacaatctgc tattgatgaa attgtcaaag gaaatgtaac cgctatactt
      661 aattttgcgc ctgacagagt aactgtccca gcttatgtca atgttcaata cattgatttg
      721 acaaccgagt tgcagacgct tatttacttt gatgagaatt actcagaagt tttttcttag
      781 gaaaatttga gtaggcttat tgatcttgcg agaactcgtc gtaattcttt caaaaatttt
      841 ttagtactaa atgaagtggt tttttcacga ccacttgttg actaaaaaaa aaaaccattg
      901 tagaatgaag cataacgctg aacaagagga gtaactggca cattcattct tagagagaga
      961 actatctgct gaaaggttct caatgacaac cagtgaaggt agcttgggag tttctgtctt
     1021 gaatggagta gagatagacg agtcgtgatc gttaactcac ttgagaggca ataatgattg
     1081 attattgcaa tttaggtggt accgcgtaaa tcatacgtcc tagaatacga aagtatttta
     1141 ggacgttttt tagtttaaag gaggaaaaca gcatgacgga agaaaataac ctatcaacaa
     1201 aatataatcc gcaagaagtt gaagctggac gttatcagca ttggttagaa caagatttgt
     1261 ttaaaccgag cggagataaa aaagcaaaac cttattcaat cgtaatcccg cccccaaatg
     1321 ttactggaaa acttcattta gggcatgctt gggatacgac cttgcaagat atgctgattc
     1381 gtcaaaagag aatgcaagga tatgatactt tatggctgcc tggtatggac catgcaggaa
     1441 tcgcgacaca agcaaaagta gaagcgaagc ttagagagca agggatttct cgttatgatc
     1501 taggtcgtga aaagttcatc gatcaagtgt gggaatggaa agaagagtat gcgagccaca
     1561 tccgcgaaca gtgggctaaa atgggcttat ctttagatta cagtagggaa cgttttacat
     1621 tagatgatgg attatctgaa gcagtacgta aagtttttgt taccttatac gaaaaaggtt
     1681 tgatttatcg tggtgaatat atcatcaact gggatcctca agcacgaaca gctctatctg
     1741 atatcgaagt tattcataaa gatatcgaag gcgcctttta tcatatgagc tatgaactag
     1801 cagatggatc aggcgtagta gaaattgcga caacccgtcc agaaacgatg ttgggagata
     1861 cggcgattgc tgttcatcca gaagacgagc gttatcaagc gctcatcggc aaaaaagtga
     1921 ttctaccttt agtcaataaa caaatcccaa tcattgcaga tgaatatgta gatatggaat
     1981 tcgggacagg tgtagtaaaa atcactccag cacatgatcc aaacgacttt gaggtaggta
     2041 atcgtcatga tcttccacgc gtaaatgtta tggatgatga tggtacgatg aatgaactag
     2101 caggaaaata tgctggaatg gaacgttttg ctgctcgtaa agcaatcgtg caagatctga
     2161 aagaaatcgg tcgattgatt aaaatcgata cgatgatcca cagtgtgggt cattccgagc
     2221 ggacaggtgt cgttgttgaa cctcggctgt ctactcaatg gtttgtaaaa atggcgccgt
     2281 tagcgaaaaa agccattgat aaccaagaaa cagatcaagc agtggaattc ttccctccaa
     2341 gattcaatca aacgttttta cgttggatgg aaaatgtcca tgattgggta atctcacgac
     2401 aattatggtg gggacatcaa attcctgcat ggtatcacaa agaaacaggt gaaatgtatg
     2461 tagggatgga agcaccagcg gatagtgaaa actgggtaca agatcctgat gttttagaca
     2521 cttggtttag ttcagctttg tggcctttct caacaatggg ctggccagat acggaaagcg
     2581 aagattataa gcgatacttc cctactagca ctttagtaac cggttatgac atcattttct
     2641 tctgggtaag cagaatgatt ttccaaagct tggaatttac tggcgaacgt ccatttgaga
     2701 atgtcttgat tcatggattg attcgtgacg aacaagggcg gaagatgagt aaatcattag
     2761 gtaatggaat cgatccgatg gaagtaatcg aaaagtatgg agcagatgct ctccgctggt
     2821 tcttatcgaa tggttctgca ccaggacaag atgtccgctt cagctatgaa aaaatggatg
     2881 cttcttggaa ctttatcaac aaaatctgga atgcttcacg tttcgttatc atgaatatcg
     2941 aaggaatgac cgtagaagag atcgatttat ctggagaaaa atcagtggct gaccggtgga
     3001 tccttactcg tttgaatgaa acgatcgaac gagtaactga gctatttgat cgttttgaat
     3061 ttggtgaagc aggtcgacaa ctgtataact ttatctggga tgatttttgt gactggtaca
     3121 tcgaaatgag taaagaagta ctttatggag atgatgctgt ttcaaaacaa accacccgta
     3181 gcatcttagt ccatacactt gatcagatcc tacgtttatt gcatccaatc atgccattcg
     3241 ttacagaaga aatatgggaa catattcctc atcagggaaa ttctctagta gtggcagaat
     3301 atcctgttgt acgtccagag tttgatgatg aaacagcttc taaagggatg gaagtattga
     3361 aagaattgat tcgagccgtt cgaaatattc gttcagaagt gaatacacca ttgtctaaac
     3421 caattacgtt gctaattaaa acaaacgatg ctaaaatcga tcaattttta gttgaaaata
     3481 caagctatat cgaacgcttc tgtaatcccg aagagttgac gatatcaagt gagatcactg
     3541 cgccagatct agcgatgtca gctgttctga caggtgcaga aatcttcttg ccgttagcag
     3601 gattgatcaa tattgaagaa gaaatcaaac gattagaaaa agaactggaa aagtggacaa
     3661 gcgaagtaaa acgtgtccaa ggaaaacttt ctaatgaacg ttttgtttct aacgcgccgg
     3721 aagaagtagt agaggcagag cgtgcaaaag aaaaagatta tttagagaag caaacggctg
     3781 tcaaagaacg aatcgaaagt ttgcgtacta ttcaataaga atagaaaaag agagtgtgaa
     3841 atcagctagc tattactaaa agctagctga ttgaacatcg ttacaggaaa gagtttgagc
     3901 ctcactctta gcttcgattc ataaggagat gtgacataaa ttttgtcgca tctctttttt
     3961 agtctactct tattatgtag gagaaggagg gaggtggatc atgtatcaag agtcaataaa
     4021 gtagttgata aaatcgttcc tctctctgtt tcttttctct ttgtcatact tttatttttc
     4081 ttatgtgttc tatttgttat aataaaagag aaatggggga attgttgatg acgattgaag
     4141 aagcaataga atggatccat agtcgattac catttggttc acgtcctggc cttgaccgag
     4201 tcgaagcttt attagaagtg gtagggcatc cagagagaaa agtaaaaacg atccatatcg
     4261 ctggaacaaa cggaaaaggt tctactgtag cttatttgag aagcctatta gaagaggctg
     4321 ggctgacagt aggtacattt acttcacctt atatcgaaac gttcaatgaa cggatcgcaa
     4381 tcaatggcaa aagcattcca gacaatgatt tgatccagct tgtaaaaaaa tatcagccac
     4441 tgatcaaaca acttgatcaa tttgaagcag tagctggtat tactgaattc gagacattaa
     4501 cagcaatggc atttgattat tttttgatga agaaagtgga cgtagcgatt atcgaagttg
     4561 gcttaggcgg cttattggat tctaccaatg tagctgtacc aatgctgacg ggaataacaa
     4621 cgattggact tgatcatacc gaaatacttg gagatacaat tgaagaaatc gctgcacaaa
     4681 aagctggaat catcaaacaa ggcgttccag tagtaacagg aaatattgcc ccagaagctt
     4741 ttactgtcat ccaacaaaca gctaaagcaa aaaatgcacc gctttatgta tacggggaaa
     4801 attataaaat aaactatctg catcctgatg agatgtgggg agaagtattt gaatttttta
     4861 atgaaatagg aaagatccct caattaacca ctccgctttt agggcaacat caagctgaaa
     4921 atgcaggagt agccatcgaa ttgtattttg tttactgtca attggaaaag ctgcctttcc
     4981 gagaaaaaga tgttttgaag ggattgaaga aatctcgatg gccaggaaga atggagcgtt
     5041 tgagtaacga gccattagtt gttttagatg gtgcccataa tacgcatgca atgaaccggc
     5101 ttgttgagaa tttgaaaaaa gaattcaaag gatatcaaat caacattttg ttttccgcct
     5161 tacgaactaa aaatgttaga gaaatgctag aacgattgca gcaagtacca aatgtccata
     5221 tttatttgac gacctttgaa catccaaaag ccatcgaatt aagtgaagta tcagatttag
     5281 caagtgagag agtatcaatc gtttcattgt ggcaattcgg attagcagat atattggaaa
     5341 agatgacaaa tgaagacgta ttagttgtga ccggttcact ttatttcatt tcagaagttc
     5401 gccatttatt aatacaatta ggaggagatc atgaagtata atgcagtgat ttttgacatg
     5461 gatggtttgc tgttcgacac agagttagtg tattacgaag ccacacaagt agtagcagac
     5521 aagatgggtt ttccttatga taaagacctg tatttaaaat tcttaggtgt ttcagatgaa
     5581 gaagtatggg cgaattatca tatgattttc tcggaatttg gcaaaacaag tgtacaaaga
     5641 ttcatagatg attcatacca ggaaacgctt gaacgttttt cgcaaggagc ggtacaaatg
     5701 aagcccggtg tgttggaact cctctctttt ttagaagaac atcagattcc caaagttgtc
     5761 gcttccagta accaacgagc agtcattgaa cttttattga agaagaacaa tctgtttgaa
     5821 cgatttgaga cgattgtttc tgcagaaaat gttcaacgag caaaaccaga cccagaaatt
     5881 ttcttgttag ctaatcagaa gctaggtaca gcgaagaaag aaacattgat tttagaagat
     5941 tcacaaaatg gtattttagc agcttctgcg gctgagatcc cggtagtcat ggtaccagat
     6001 ctgcttccac catcccaaga attgatcaaa aaaacagctg gggttgtttc ttctttacat
     6061 gaaatccctg cattgttaaa ataaaaatcc atctcttttc gtatcttatt ttagataaga
     6121 tagaaaggag atgttttttt gggaaaacga ttgatcaaag aagtacctac tagctcttta
     6181 ccaagggaac gtatggaaat ttatggcgcg gaagctttat cggatcagga gcttttggca
     6241 atcttactgc gtaccggtca acacccttat agtgtgatgt cgattgctgg aaatctgtta
     6301 aaaacgtttg gaggactggc ctctttacga caggctactt tgcatgagtt agaagagatt
     6361 cgagggatag gacgcgtgaa agcaatcgaa atcaaagcct tgatcgaatt aggtcgacga
     6421 attcagacgg atcatgaaag agcggctcca ccggttcgta ccagctacga attggcccag
     6481 caattgattc tggaaatgaa agatcacaaa caagaacatt tggtttgtat ttatttggac
     6541 acgaagaatc aagtgatctt aaaaaaaaca gtgttcatcg gttcgctgaa tcagtcagtc
     6601 gctcatccta gagaaatttt ccattatgct gtacgttatt gtgcagcaag gatcgtttta
     6661 gcgcataatc atccttctgg taatgttatt ccatcgcagc aggatatgaa ttttaccaaa
     6721 aggatacaaa agtgtggaga aatgatgggg atcactgtac tggaccactt gatcatcgga
     6781 cgcaaacgat attttagttt gagagaagaa ggaatgatgg aagagaagta agttgctttc
     6841 ttgcaaaaaa aatgaagcaa gtgtacaatt atattgtaat tttgtttggg aatagaagtt
     6901 gaaacatctg ttgcacctct atcgtacacg agcaatgtta caatttaaat tagtgctttt
     6961 ggcacgagga ggatattatt atggaaaacg gaacagtaaa atggttcaac gctgaaaaag
     7021 gatttggatt tatctcacgt gaagatggaa gcgacgtatt cgttcacttc tcagctatcc
     7081 aaggtgacgg attcaaaaca ttagaagaag gtcaagcagt gactttcgac gttgaagaat
     7141 cagaccgcgg cccacaagct gcaaacgttg taaaagctta attttatctg taaatcaaat
     7201 tgatggtaga catcaatttt tacgagagaa caaagcgagt aacaaaaata cctgccacaa
     7261 gagacaattt ctcttgtggc aggtattttt ttgtatgaaa aagtaaataa atttaagagg
     7321 ctatgaaaga gccaccttgt atcaaggaat aagaacaaac aaaaatggct tctcatgttt
     7381 ttcatttgtt ttctcttata ttcaggacaa ggtgctgatt tcataacctc ttatttattc
     7441 ttcatctggt gtcattacca ttggcaaaat cattggatgt ctttctgtac gttcgaataa
     7501 gaaaggctga agcgcgccag tcatcgcttc tttcaattta tattctgaac agtcaggtcc
     7561 attcaaacat tctcttaaag cgtggaataa gattcgctga gcttcattga tcatttctcc
     7621 tgattctcgc atgtagacaa atccacgaga gagaatatct ggaccagcca agatttcttt
     7681 tttcttgata tccactgtcg cgacagctaa tacaagacct tcttctgaaa gcaggtgacg
     7741 gtcacgtaaa acgacattac caatatcacc gatcccgcta ccatcgatat acacatctcc
     7801 agccacaaaa tgcccagcag gacgcgcaga atcgctagtt aacgctaaaa catcgccatt
     7861 ttccatgatg aagcagtttt ctgcaggaac acctacatct tgtgctagag aagcatgtac
     7921 tttcaacatg cggaattctc cgtggacagg aataaaatat tttggcttca tcaaacgaag
     7981 cattaatttt tgttcttctt gtccaccgtg accggaagta tggatgttat tgatttttcc
     8041 gtgaatcact tctgcaccag cttcagacag caaattgatc aaatgattga cacttgttgt
     8101 attaccagga ataggtgaac ttgaaaagat cactgtatcg tctggctgga tttggatttg
     8161 acggtgagta ccattcgcga tgcggctcaa cgcggccatc gcttctcctt gagaacctgt
     8221 acataggatc atcgtttcat tggcaggcaa gcgattgatt tcgtgtgcat ctacaaatgt
     8281 gccgtctgga actttgatat atcctaaacg ttgaccgttg acgatggcat tttccatgct
     8341 tcgtccgaaa acagcgattt tacgaccagt tgccacagcg gcatctgctg cttgctgcaa
     8401 acggaagatg ttagaagcaa agctggcaaa aatgatacgt ccttcgattt ttgaaaagat
     8461 cttcaaaata gaatgcccaa tcgttttttc tgatttagta aatgttggaa tctcagcatt
     8521 tgtactatca gataaaaggc acaagactcc ttcttccccg atacgagcca ttttatgcaa
     8581 gtttgctggt tcgccaacag gagtgaaatc gaatttgaag tctccagtcg ctacgatatt
     8641 tccagaaggt gttttcacca cgatccctaa tgcatctggg atactatggg tcgttctgaa
     8701 aaagctgaca gaagtctttc taaaacggat gatcgtatct tcattgatct catggagctc
     8761 tgcatctcga agcaagccat gctcatctaa tttgtttgtg atcaacgcta atgcgagagg
     8821 accagcatag ataggaatat ttgcttgttt cagcaagtag ggtattccgc cgatgtggtc
     8881 ttcgtgcccg tgagtaatca ccaaggcttt tactttgtgt aagttttgta tgatgtagct
     8941 gtagtcggga atgacatagt caattccaag taaatcgtct tccgggaatt tgatcccggc
     9001 atcaatcaaa atgatttcat cttggaattg taccccatac gtatttttcc cgatttcacc
     9061 taatccacca atagcaaaga cgcctgtctc gttatttttg atggaaagtt tcatattaaa
     9121 actccactaa tgagaaatca gcattttctt tttcgtactc tagatgactt ccttctagaa
     9181 gttgaacgaa ttcaatattg tatggggtat tttcttccac acgttggcga gcgtctacat
     9241 cgctttttgc ctcaatgtaa agagattttg tttcttcccg tttagggttg cgtacttttg
     9301 tttcttgata ataaacttta tagatcattg ttttgtctcc tttatctgcg taaagcagtg
     9361 atttagctag ttgatttttt tagacaacac aaaacgaggg gacaagccac ctggtttttc
     9421 atatgctttg actagaatac tggattcgag tcaaagagac aagcctcgtt tttgcttatc
     9481 tgttcggata ttttttcaac cgtaccttct gtataaaaaa tatacaacaa ttaattgtta
     9541 ttctagcata aaacagcaaa taagtataga aatcaactag attgaaagaa aaaatcaatg
     9601 tttatcatcc cgctataatc ataatgactt ttttatgaga gaagtgttct attaataggc
     9661 tcgttgtgct atcattttta gtaatgaaaa tgtaacaaaa gattaaaagg agatgagaaa
     9721 gtgaaactaa tgtggcatta taccatgcgt tataagaaat tcttgttttt caatttcata
     9781 tgcgtatttg gttttatttt gattgaatta ggacttccta cgattttagc acgtatgatc
     9841 gatgtaggaa tccgcaatga tgattttgat tatgtgaagc aacaagggat atttatgatc
     9901 gttattactg taatcggtat tattttgaat atcttgttag gttattttgg ttcgaggatt
     9961 acgactaata tcgtagcaga tattcgagat gatttgttcg aaaagatcca aagttattcg
    10021 catcaggaat acgaaaatct aggcgtatct tcattgatca ctcgtacaac aaacgatgct
    10081 tatcagatca tgttgttcct gcaaaatatt ttacgtatcg gttttatggc accaatgatg
    10141 ttcattgtca gtttgtacat ggtcatgcgt acaagtgtga cactcagttt gtatgtagta
    10201 ggtgcattac ctttactatt attggcagtc gtagcgattg ctaaggtgtc tgaaccgtta
    10261 tctaaaaagc aacaaaaaaa cttagataaa atcaacagta tcttgcggga aaatctttca
    10321 ggattgcgtg tgattcgtgc attcgtcaat gaaaagtttg aagaaaaacg ttttgctgta
    10381 gtcaatgaga attatgcttc tagttcaaaa agcttattcc gtttgatggc tgttgcacaa
    10441 ccgggttttt atttcttatt taatatcgta atggtattga tcatctggag cggggcagtg
    10501 caaatcgatg caggcgagct tcgtgtagga gatttgattg cgtttatcga gtatatattc
    10561 catgccttgt tctcattcat gttatttgct agtgtgttca tgatgtatcc aagagcagct
    10621 gtttcagctg gacgtatcca agaagcccta gatgccaaac cttcgattgt agaagatcca
    10681 aatggtatat ctgatacaaa aactaaaggg tatatcgaat ttcaaaatgt aacatttgct
    10741 tatccaggcc attcgcaaga gccagtgata cgaaatgtca gttttacagc ctctccagga
    10801 gagaccgttg cttttattgg aagtaccggt agcggaaaat ctacgttgat ccaattgatc
    10861 cctcgctttt atgatgtgag tgaaggaaag atcttgatcg atggagtaga cgtgagagat
    10921 tatcggctaa gcaagttgcg agataagatt gggtttattc cgcaaaaagc gctgctattt
    10981 actggaacga ttgcagataa tttgcgatac gggaaagaag atgctacgca agaagaaatg
    11041 gaacgtgcag ctgagattgc tcaagcttca gaattcattt ctcgaaaacc agatggattt
    11101 aatgaacatt tatcagaagg tggttccaat ttttcaggtg gacaaaaaca acgattggca
    11161 atagccagag ccatcatacg ccgtccggaa atctatattt ttgatgacag cttttctgca
    11221 ttagattatc aaacggatgc gaagttacgt gctcgtctga aaaaagaaac gacagaatct
    11281 actgtattga tcgtagcaca acgtgtggga acgatcatgc atgcagataa gatcatcgta
    11341 ttaaatgaag gagaagtcgt cggtatgggg acgcatcggg agttgttgga aaaatgcccg
    11401 atttattatg atattgccgc ttctcaatta tcaaaggagg aattagcatg aaaaaaacct
    11461 tttcttcctt aaaacgttta gctcgatata tcagaccgta tcgtgagact tttcttttag
    11521 tgatcctatt tacagttctg acagtggctt tcaacgtggc tttgccatat gttacaggac
    11581 ttcctactac agaaatcagc cgtaatattg ccaatggcga atcaatcaat ttttcttata
    11641 tattcaaatg tctcatttgg atcacagttg ttggaatagg gtattgtatt tcgcaattac
    11701 tttctggtgt tttgatgaca aatgtcgttc aaagtgccat gcatgatttg agaagagaca
    11761 tagaagaaaa aatcaatcgt cttccggttt catatttcga taaaaaccag caaggaaata
    11821 ttttgtctcg tgtgacgaat gatgtagatg cagtcagcgg tgctttacaa caagctttta
    11881 ttggtatcgt aaatgcgata ttgggaatta cgttggctgc agcaatgatg ttttatatcc
    11941 agccgatgat ggcgctgatc tctatgatca tgattccaac atcgatctgg atctcaaaac
    12001 gagtgatcaa tgcttcgcag aaatattttc aaagcatgca gaattctctt ggtgagctaa
    12061 acggctacgt ccaagaaaat atgacaggtt ttagtgtatt gaaagtatat ggacgcgaaa
    12121 aagaaacatt ggaaggattc aaaaaagtta atcacagctt gaaatacttt gggtttcgtg
    12181 cagcattcat ttctggcttg atgatgcctc tagttcaatt aactgcctat gctacttata
    12241 ttggtatggc tgttctagga agcttttatg ttattactgg ggcgatcgtt gtcggtcaac
    12301 tacaagcatt catccaatat atttggcaaa tcagtcagcc aatggggaac gtgacacaat
    12361 tgtcttcagt tttgcaaagt gcatcagcgg caacgaaacg tgtattcgag attttagatg
    12421 agccagaaga aaaagaaaac aaagtagatg cttcactgcc agaaacgatt ttaggagatg
    12481 tgacattcga tcatgtcgat tttgcatatg atccgaagaa accattaatc caagatttga
    12541 attttgaagt gaaagctggt caaaccgtag ctgtggtcgg tccgaccggt gccggcaaga
    12601 cgacattgat caatctattg atgcgttttt atgacgtaga caaaggagca ataaggattg
    12661 atggaatcga caccaaatca atgagtcgca gtgatgtgcg ttcgctattt ggtatggtct
    12721 tgcaagatgc atggctttat caaggaacga ttgcagataa tatccgcttc ggaaagcttg
    12781 atgcgacaga ttatgaagta gttgatgctg cgaaaacagc aaacgtagat cattttatcc
    12841 gaacgatgcc agatggatat gatatggcca tcaattctga gggagacaat gtgtctttag
    12901 gacaaaaaca gttgctgacg attgcccgag cagtggtctc cgatcctaaa atcttgattt
    12961 tagatgaagc aacaagttca gtagacaccc gtttagaagc gttgattcaa aaagcaatgg
    13021 atcgcgtgat ggagggacgg acaagtttcg tcatcgctca ccgtttatcg acaatccgtg
    13081 atgcagatct gattctagtg atggatcaag gtcagatcat tgaaaaagga acgcatgaga
    13141 gtttattggc acaaggtgga ttttatgaaa aactgtataa cagccaattt gctgaggaag
    13201 cagaataagt catataagaa taaaacagtt taaaacttat tttttgttct ctattcttga
    13261 taatggtaaa gtaaagttat caagaaaagt gaggacacgg agatggaaca gtttttaaat
    13321 gaaaaaatta ctgaagccaa aagagaagtt gatcgtttaa cgcacgtctg tcagacgaag
    13381 ccttttgatt cagctgattt ttttgaaaat gagtttcaaa tcgaacgctt ggcagcacaa
    13441 atagaagtgt acgaattaat tttaaaaaaa gtaatagaag aaaatataga tgtacaataa
    13501 aaacaggtaa aacgtcagtt accagatact gtaaatagac atctggcctg agcaggtttt
    13561 acctgttttt tttcttatga aataaatata tgctatgata cctttattca ataggattag
    13621 tttctacaaa aaatgaaagg agaaaaataa atatggaacg gtttatagca tcaaatgcca
    13681 cagtgattgg tgatgtgaca ttgtcagaag atgtgacgat ctggtatcaa gctgttttac
    13741 gcggggacag taattggata aaaataggac aaagaacgaa tatccaagat ggtacaatca
    13801 tccatgtcga tcatgatgca cctgtagata ttgcggagaa tgtgacggta ggacatcagt
    13861 gcatgctaca tggctgtaca atcgaaaaag gggcgctgat cgggatgggg accacgatat
    13921 tgaatcatgc ggttattggt gagaatagtt tgattggtgc tggatcatta gtaacagaag
    13981 gaaaagttat tcctcctaat gtcttggctt ttggtcgccc agctaaagtg atccgtcctt
    14041 tgacaaaaga agaaatacaa aaaaacaaag aaaacatcca gcattatgtc gagataggtc
    14101 ggatgcatgc gcaaggaaaa ttcaaggagc aaagataggc agtagcatcc ataaaataaa
    14161 aaaggatggt cagtttgagt tgaccatcct tttttatttg gtttagataa gagagcttaa
    14221 aaaagcttcc tttgaaacag attaatttaa tgaagaactg ttttccatga cttcatcgat
    14281 caatccatat gcttttgctt gttcagctgt catatagttg tcacgatctg tatctttttc
    14341 aatcacttca agcggttgtc cagtgcgttc agctaaaatt ttgtttaagc gttcgcgtgt
    14401 ttgcaaaata tggcgtgccg caatttcgat ttcagttgct tgcccttgag cgccgccaag
    14461 aggttgatgg atcatgatct cagcatttgg taaagcaaat cgtttacctt ttgtaccagc
    14521 tgtcagcaag aagcttccca ttgaagcagc catacccata acaattgttt ggacatctgc
    14581 tttgacaaag ttcattgtgt cgtaaatagc catacctgct gtaactgaac caccaggaga
    14641 attgatataa agatagatat ctttttcaga atcttgagcg tctaagaaaa gcaattgggc
    14701 gatgatcgaa ttagcaagat catctgttac ttggccgctt aacatgatga tacggtcttt
    14761 caataaacgt gagtagatat cgtaagctct ttcacctcgt gaagattgtt caatgactgt
    14821 aggaattaaa ttcataatag agttcctcct tgatttcgtt tagaaatagt gtaccataat
    14881 ttagtttcta atacctaaaa tgtagtatac atttttggtc aaaaaaggtc aaataaaaaa
    14941 cttaggcaaa ttagtcgcat aaacccgctt tatggtatga taagcagaga aacaaaacaa
    15001 ggaggaacaa cagattgata gttggtatta ctggccttat cggagtgctg acaggtgctg
    15061 tagttgtcta tatcggcatg atactgcaaa tgcgtcactt ggaaaataaa gaacagcgta
    15121 gacgtgaatt ggaattgaaa gtcaaagaaa tcgagacgct gaatcaatta aataaaaaga
    15181 tcaacgagat cttgcaaaaa cggacaacgc tgatggaaga atatgtcagc tttgatgcat
    15241 ttgatgattg ttatatcacg attgacgatt ttgcgtatct ccaatcattt tcagcgcaaa
    15301 atagttttta tctgccaaat tatattttag acgagctatt taagaatatc tcccatcgaa
    15361 aagtgatttt atctccagat gaaacaatga agattggtgg atatgcttat aaaggcggac
    15421 gcgtgatttt agagaatttt acggatagtc tgactgaaat gatcaatgaa aaaaaagctc
    15481 agttgaagac tatgacgcgc cagccgattg gtttcttctc gaaagatgat gtttggagct
    15541 gatattttga agcattgccg ttgcacatga gagcgtggta atgctttctt tttttcttaa
    15601 tgatacaata gaactgaacg gagtgaagaa agatgttaca aatctatgcc catcgcggaa
    15661 gcagcggcac ccacccagaa aatacgcttc ctgcatttgc agaagctgta cgagtaggtg
    15721 cagatggtat cgaactagat gtccatctaa gcaaagatgg ttatttgatc gttatgcacg
    15781 acgaagaagt ggaccggacg actaacggta aagggctgat tcgagaaaaa acattggaag
    15841 aactcaaaaa attgaatgca gggggcaaat tcagcaaaga atttccagca gctaaagttc
    15901 ctgaattgag agaagtgtta ggactgctcc tccaaaaaaa ttaccgaggg atgctaatga
    15961 ttgaaattaa aactgatcag tatgaatatc ccggtatcga agaaaaatta gccgaaacat
    16021 taaaaagtag agattggcct tttcaacatg catattgcag ctttcatttg gattctttgg
    16081 aaaaaatcgc attactggaa ccggagatac agctggactt attgatgagt acttctgata
    16141 aaaagatcca actagcagca gaaacccctt atatagaagg agtacatcca aaaaatactt
    16201 ggttgttcga acatccagtc caggcagctg attttccaaa agcaattcgt gcatggacga
    16261 ttaacgatga agaagaaatg gccaaatgtc aagaactcaa aatagatgga ataataactg
    16321 attttccgga gaaagctctt cggtggaaac aatcaacgaa aagtaggtaa aatatggaaa
    16381 aagtattagt gatcgtcggt ccgacagcag tcggtaaaac agcgctaagt gtggaactcg
    16441 cacaactatt tggaggagag atcatcagtg gtgattcatt gcaaatctat aaaaatctgg
    16501 atatcggtac agcaaaaatc aaagaagaag agatgaataa tgttccgcat catttgattg
    16561 atgtgatcga acctactcaa cgttactcag ccgctgattt tcagcattca ggtcgacaat
    16621 tgattaccga gattgcgaac cgagggcacc tacctatcat agctggtggt acgggtctct
    16681 atatccaatc ccttctatat gattatcagt taggagcgac agaagaagcg aatcctgaga
    16741 ttagaaaaaa gtatgaaacg ttagctgaaa caattggttc ccaagcatta tggaatcagt
    16801 tgaaagaaaa agacccggca gctgctgaga aaatccactg gaacaatcaa cgcaaagtga
    16861 taagagctct ggaagtttta gagacgacag gacatagtat cacggcacct aaagaagagc
    16921 caaagcaatt gtatgattac ctcatgattg gattagatac gaagcgtagt attctttatg
    16981 aacgaatcaa tcaaagagtc gatttgatgc tagcagaagg tttagtagca gaagcgcgta
    17041 aggtgtatga gcttggagaa gtccaggcca gtcaaggtat tggatataaa gaatttttcc
    17101 cttattttga agggaaagaa acattggaag aagcaacaga acaagtcaaa ctacattcga
    17161 gaagatacgc gaaacgtcag ttgacgtggt ttcgtaaccg tttggatgca cagtggtttg
    17221 atcttataag tgagccaaat caaaaaagtc agattgagca aacaatcaaa aaatggctgg
    17281 aggcggaata aaatggaaga aaaagtgatc atcgtagggg tagaaaccga agcaaaccag
    17341 cgttactttt cagagtcaat ggaagagcta gttcagctga cgaataccgc atcaggagaa
    17401 gtcgtattca caattacaca aaagagacca caagtggatc ggcaaacgat tatcggtaaa
    17461 gggaaattac aagaattagt tcaacaagcg gatgcgcatg aagcggattt gatcatcttt
    17521 aatcatgagc taactccgag acagagccaa ctgattaccg atgctgttgg tcttccggta
    17581 attgatcgcg tgcagcttat cttagatatt tttgcgatgc gtgctcgttc gaaagaaggg
    17641 aagctgcagg ttgaacttgc tcagttagaa tacctgctgc ctcgtttagt agggcaaggg
    17701 aaaacattat ctcgtcttgg cggtgggatc ggaacaagag ggccaggtga aacaaagtta
    17761 gaaacagacc gccgacatat acggaataaa atttttgctg ttaagaaaga attgaaagaa
    17821 gtagaagctc atcgagagcg caatcgccaa aaaagaaaaa atagcgagat ttttcagatt
    17881 ggacttattg gctacacgaa tgccgggaag tcaactatct tgaatctatt gacacaagcg
    17941 gatacttatt cgaaagatca attgtttgca acgttagatc cattgactaa gagatggcgt
    18001 tttgctgaag gatttgagat tactgtaacg gataccgtcg ggttcatcca agacctgcct
    18061 acgcaactga tcgatgcttt ccattctaca ttagaagaaa gtcaaaatat ggatcttttg
    18121 ctacatgtag tcgatgctag ttctccagat cgtattttac aggagcagac tgtcttaaaa
    18181 ttgatggatg aactgaatat gaaagaaatg ccgatactga ctgtttacaa taaggcagac
    18241 cagatcgacc cagcgatgtt cacgcctacg ctattcccaa atgtattgat ttctactcag
    18301 acgaaagaag gtaagatggc gttgatcgaa gcaatcaaac gtcagctgat ggaactaatg
    18361 accccttata cactttctgt gccaagcaac gaaggacaga aattaagcga gttgagaaga
    18421 caaacaatgg ttttggacga agcgtacatg gaagaaacaa acgaatatga agttaaaggg
    18481 tttgcaaaaa ccaattcaaa atggttaaga aaaaaccaat aaaattttat ttttttaa
//
LOCUS       DAFLVO010000057        18330 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.057, whole genome shotgun sequence.
ACCESSION   DAFLVO010000057 DAFLVO010000000
VERSION     DAFLVO010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18330
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.057"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            21..542
                     /locus_tag="L1U99_002040"
     CDS             21..542
                     /locus_tag="L1U99_002040"
                     /inference="COORDINATES: protein motif:HMM:NF024252.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1212575.1"
                     /translation="MHIGDKIHKLRRLNNETMNDLVKQTGLSKSWVSDIESGKKQRAD
                     FNKICAIAKHYKVSLEYFQDDYLDSDEHEDIIPLTDETRVKSVKSLEQSLKYLNNKQE
                     PNLLEIKLKDTDSVPEVYYKGQKLEGLIDVSYHYHTTTDVVAGSTNDINMEYLGEVTK
                     YPDIKTIGHKRDV"
     gene            543..860
                     /locus_tag="L1U99_002041"
     CDS             543..860
                     /locus_tag="L1U99_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBN1212576.1"
                     /translation="MKEARPRDEIDKLYKTKRWRDLRQVVIARDFGMCQECKRRGRNT
                     RGTIIHHIVEAREDLSLFWSVDNLECICVACHNREHPERSGGKKKPKPKSHIVKMYST
                     PER"
     gene            complement(1017..1181)
                     /locus_tag="L1U99_002042"
     CDS             complement(1017..1181)
                     /locus_tag="L1U99_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HBN1212577.1"
                     /translation="MGELYKPGEDNKPKGTYKEVGPRGGNVQGGREVKIDPGDRLPPT
                     SQKGNKWTKK"
     gene            1284..1805
                     /locus_tag="L1U99_002043"
     CDS             1284..1805
                     /locus_tag="L1U99_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HBN1212578.1"
                     /translation="MPQPAKSAKLQLLNGNPNKKNTEELRKRAAAEDKLKMATDKIKP
                     PLWLDSLGKDTFEFIADELLSVDLISNPDVHTMALYSNWYSQYVSLEKQLRKLQREYK
                     LNYALAKKEAEARGEPFNEPNELIGNPLSRQMDTASRNLRSFGADLGLSPAARAKLAI
                     KMADDGGDDDDDF"
     gene            1792..2265
                     /locus_tag="L1U99_002044"
     CDS             1792..2265
                     /locus_tag="L1U99_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003666010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HBN1212579.1"
                     /translation="MTTSNILDMSYTERVDYWQSYLEEQASWGGFLKCPYPELLTTWY
                     AERLIDGSIPASKENIQAAKRHMRDLQRQGTDDFPWIFDEEKGHRPIRYIEKKCKPTE
                     GDFGSFVLQPWQHFIIGSMYGWVHRDTGERRFREALIFVGRKNGKFCRLKIGQNR"
     gene            complement(2272..2430)
                     /locus_tag="L1U99_002045"
     CDS             complement(2272..2430)
                     /locus_tag="L1U99_002045"
                     /inference="COORDINATES: protein motif:HMM:NF024064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix domain-containing protein"
                     /protein_id="HBN1212580.1"
                     /translation="MDKYGLKNRIRISNAIDKDLYEGLKKMSEETMVPMSKLLDKAIE
                     LLLKESQK"
     gene            2523..3284
                     /locus_tag="L1U99_002046"
     CDS             2523..3284
                     /locus_tag="L1U99_002046"
                     /inference="COORDINATES: protein motif:HMM:TIGR01453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBN1212581.1"
                     /translation="MKKYIIYKHLNKINGKIYIGVTNDIGRRWRSGGIEYKPPKNETQ
                     HHRSFWNAIQKYGWENFDHLIIEEDLTMKEAFEKEKFYIELYDSTNKKKGYNIAKGGN
                     GGIIYKVHPKGMLGKKQSKEFSSNHSKWAKNHKNNCMTNGDVVWGVTHEHPKGMLGKH
                     HSKESIMKKKAYSGENAVTSKPIVAIERDGTKREFHSAKLCMAYYSISTCVFYRLLKD
                     GAPYVINPKANYRNKEKILAIEGIMFKHKEDTEVS"
     gene            3504..4823
                     /locus_tag="L1U99_002047"
     CDS             3504..4823
                     /locus_tag="L1U99_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003666013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBN1212582.1"
                     /translation="MVAYDDEQGANVYVLANARDQASLLFDKAAEMVKQSPALFKKFG
                     KPKRSSINYAPAFSKMEPRASDSRKLDGLNTHFGIFDEIHEFTNYNLINVIKKSRGTR
                     KQPLIVYITTAGYVLDGPLMSYFEQGVDCLEHLEDDIDERTFYYLAKLDSAEEADDPR
                     LWIKANPNICLMNFVGMLDDYVKDKKDPKEYADWITKQFNLFSDIDELSFVDMPTIKR
                     NNKTIDIETLKGKKCVGGFDLSETEDFTAAVLEFPLETGEVFILQHTWIPQARFDRDN
                     NQERIKAWEKVGDLTIIPGDYVNYEYVLNWFVENSKIYDIVKINYDKAKALRLNKELE
                     NAGFETNEIRQGFLSLGGPMQNFKEMLLDGKVIFNNSKLYRWYLSNVKLVMDRNSNWM
                     PSKQSKSRKIDGFAASLNSHAEVLNMLVNPVGTGKVTYYSISDLMNM"
     gene            4839..6059
                     /locus_tag="L1U99_002048"
     CDS             4839..6059
                     /locus_tag="L1U99_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBN1212583.1"
                     /translation="MSILDRLRSFGRAKPKASKQEYFLNDPGLIPYLVGKDEISEGIF
                     SVISRVSNVFASLPLKMIDAEFGQPDDCPAYNLLSEGPRYFTKFDFFRDVEVLRNYQG
                     NAYVQIFRNINGEVADMALIKPGACHPVIDMDSGELYYQVTATDKGSYKQVIYVHYME
                     MLHFKQPRFGGLEGTDPTKVLTNTLGYDREVRKISLSQLKGGNEGLKVKFASNVDEEA
                     KKATVKNIADFYRQNGGLLVEENGVEIERLQRELVDSKLLDTDKVSRSRIAMVYNVPE
                     HFIGSNQSSYSSQEQLNMEFLTYNLVPTVNQYEAELNKKTLSRTEKAKGYRYKFNVAS
                     LLRADTQARGQFYQIMRRGGAYSANDVRRFEDLQPINKTGMDDYHISGDLYPIDMDPT
                     LRKTNSSKSVAENG"
     gene            6094..6771
                     /locus_tag="L1U99_002049"
     CDS             6094..6771
                     /locus_tag="L1U99_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HBN1212584.1"
                     /translation="MKKVTLSGDVVDNDTAWLYDWFGIDCISPGKISAALTEAAGDEV
                     ELDISSNGGDVLAASEIYTAIRAYPGKVSGNVVSIAASAASVIACACEPLRISPTAHI
                     MIHNAWVTTSGNAEELKANAEMLSSVDESIVNAYEIKTGLDRKKLADLMAKDTWLNAQ
                     TAVAEGFADEIMFAEAPVTVLNASQPVIPKNAVTKLKNLILKAETPQEETLLQKKLKA
                     LNGGKNE"
     gene            6768..7964
                     /locus_tag="L1U99_002050"
     CDS             6768..7964
                     /locus_tag="L1U99_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBN1212585.1"
                     /translation="MNLEQLKNAWVEAGSKVSDLNAQLNAALVDDEKTEEDVVSLQAQ
                     VKAARAKRDGLKEQVANMEAEQVLNVKKEPLDKKDENLKNKFIKDFKAMVNGDPAIMA
                     TLTSNTDESGNAIGLTIPVDVQTTIHTLVRQFDSLQEYVNVEKVTTTSGSRVYEKWSD
                     INPLTALDTEDGEIPANDDPALYLIKYLIKRYAGISTVTNSLLKDTAENILAWLSNWI
                     AKKVVVTRNTKILAAIDGIKAAQKKDVTDVDGIKDIINVQLDPAIEATSMFITNQDGF
                     NVLDKVKRADGSYLLQKDVASATGYTFLGKPIKKIASRFLPNKGTQATPKYPLYIGDL
                     KEAVTLYDRENMSLLTTNIGGGAFETDTTKVRVIDRFDVQLVDDEAVVLATFTSIANE
                     VPVTNG"
     gene            7979..8302
                     /locus_tag="L1U99_002051"
     CDS             7979..8302
                     /locus_tag="L1U99_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBN1212586.1"
                     /translation="MILDPKMDLDEIKNALKIDTDDDDVEVRRAVQAAIAYIRGAIGN
                     DKPSFYKQENDTVDLINLAILQLADHYYNARSATVSGNLREYDLGFTSLILQLKARYL
                     LFVEE"
     gene            8306..8641
                     /locus_tag="L1U99_002052"
     CDS             8306..8641
                     /locus_tag="L1U99_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBN1212587.1"
                     /translation="MPLIQTGNLNQRIKFVRDTTVKDEDGQVVRTSTTILTCWASVQT
                     QRLNDIKTSIGTALEGTLTFIIRYQQKSELTNDMKVRWNGKTFEIITITKGEFAKDFT
                     TIIAKEVSK"
     gene            8638..9033
                     /locus_tag="L1U99_002053"
     CDS             8638..9033
                     /locus_tag="L1U99_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212588.1"
                     /translation="MSVEVDATEVYKALREVKANVQRVESPALRKAGEYAQEKLQQNT
                     PYWDGTKSNGKRGSYMQEHAKDHVVTSSVKNGLIEVGYDKDVSWRMHFIEFGTIKQRP
                     KGFVQKTQKQIEKQVTQIIADEVKRRLGL"
     gene            9030..9401
                     /locus_tag="L1U99_002054"
     CDS             9030..9401
                     /locus_tag="L1U99_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212589.1"
                     /translation="MKTAVSQVYSILNSNEKTKNIDFYTNSVPESAQTVPSLPVGRIT
                     EIFGNYEDFASNNPLTIQFNVQVDVWVSTLKEVDAFYFALDEIMRGNGWQCAYTEQTD
                     DEDLEGAKRIIKRYVANISLN"
     gene            9417..9977
                     /locus_tag="L1U99_002055"
     CDS             9417..9977
                     /locus_tag="L1U99_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1212590.1"
                     /translation="MATVGFESVIFGVKTGAGGTLKELVADKSKGGAIEAKITGLGAT
                     SNTTYASNVPFFIASKGVSSPKVTLDVADLMDNGIYSEIIGAKTVDGVNVIGSETEAP
                     YVSVVMVTANKEGKRLFMGLAKGKFSHPDIDMKTAEDKGVELQTDSIEGEFISDERGY
                     VYLTAVESEEMTLQKFKDLVNNKAGE"
     gene            10104..10415
                     /locus_tag="L1U99_002056"
     CDS             10104..10415
                     /locus_tag="L1U99_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212591.1"
                     /translation="MIELQLKLDGKKKTFKQQDISARAMRECIKFYEKAEKADLTDLE
                     AIDSMIAITADIFQDPAVTFDAILDGLTASELVPALESVFEQINELGNNEKKQTASKK
                     R"
     gene            10439..10630
                     /locus_tag="L1U99_002057"
     CDS             10439..10630
                     /locus_tag="L1U99_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212592.1"
                     /translation="MDQIYKDLIESGWTMRDVDEADYHYLLHLFGEVESGEEYVDGAD
                     FIKQFLSAEDLVKLEEGGK"
     gene            10630..14475
                     /locus_tag="L1U99_002058"
     CDS             10630..14475
                     /locus_tag="L1U99_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBN1212593.1"
                     /translation="MAGKGQPAGNIKLGISLDSTNFGNTLDEINAKVKQAESNMRANL
                     KAYDSAGRSYEALSQKTKDLSTVMEGQNAKVRELTKRRDEAISKYGEESKQVANLNTQ
                     INNATAKYNAYSRQLNDTKKELVYSKTAVNDLSNEIKENERQMNAEVKALKAAGDESG
                     AFEAKQKGLAKQTELSEKAIEEQRKVVKLMADEFGDSANETEDAKRALEKLERQSQIS
                     SRQLEALKSSSDQSGKKIEDFGDKSTRSARKLDGLKDKLGSLKSAFSFGAVAGLAHNA
                     ISSVVSGVQGLVGEAVNASDSLMKFSKTMEFANFGKSQIESSKKEMKDYADKTVYGLE
                     EILNTTAQLASNGIPNYTELTKAAGNLNAVAGGSSDTFKSVAMMLTQTAGAGKLTTEN
                     WNQLADAIPGASGLLQDAMLKNGAYTGNFRDAMAQGQITSDEFNQAIVQLGMNDGAVK
                     AATSTDTLSGSWEQMKSTVINGLQSIIDKVGVENITGFINRVTKGIENSIPKITQFIG
                     WLRDIGTWIVENREPLTWIVGIIGGITLAVKALNVASMLLAITGGTLAAPFVAIGVAL
                     GALAGALVIAYTKSETFRNIVNAAFTAVKNVVMSVINNLVEYYKMLWSVLQWLWEKIK
                     EWASWIGNKFIEMKNSVVNTVQNLWNGVKNFFSNGVGDTWNKVVGWVKNIFNKATELK
                     NKVSDAIGNLWNGIKDTFRRGIDTVFNWFSELPTKMKNAIIGGKNAIVDAFKSIFNAA
                     LKAIGKPVNAIIHGASWVLEKLGADKLEEWKVPQYAKGTPNGGHPGGPMMVNDGRGAE
                     AVITPNGQAFIPRGRNVVLNAPKGTHVLTAEETAYMTGNKAPRYRYAKGTGFFGNLWN
                     NVKGFAGDVGNKLKDVVGDVWDFVTDPGALARKVLNGLGVLEGLVKYPLDVGKGILSK
                     ATEALTNKITELFSSGSLDTSMGMQGVYKYLADVAVAVMKKFPGFVATSGYRPGDPYS
                     HGKRNAIDIALPGVTGGSPRYTEAANYAFEKFANKIGYVITNGKVRDRSGQSGTGIHN
                     DWRPWPDGDHYDHVHLNGVKDPQNTQISGDSVGGSGVERWRNVAIRALKMTGQYSTAN
                     LNALLNQMRTESNGNPNAVNNWDINAKNGTPSKGLLQVIDPTFRQYAMPGFNSNIFDP
                     LSNILASIRYALSRYGSLTNAYRGVGYANGGIVNQHQIAEIAEGNKPEIIIPLDKAKR
                     SRAMQLLSIAMDKLGVSPKTYGNATTVSSDYEILEAIEKQAATTNQLLSLLLAFFKGN
                     SRTDRDLALDIQKILVRRM"
     gene            14476..15348
                     /locus_tag="L1U99_002059"
     CDS             14476..15348
                     /locus_tag="L1U99_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate protein"
                     /protein_id="HBN1212594.1"
                     /translation="MRTVLLRNRINEEIDLSTEDYFATGLSNMGFEVKKEHVGQWGNF
                     RESSENVEISEFQSSVIISVHGFREKELYNSLVQFLSEGPFELEFAFDGETMVRRCSL
                     KSLSKTEIDPKTSLLTDTLELYFTSNWYSVKREKLIQRPNVVKTRGKVFPYKRSYIYT
                     QNLWEKKGVFKFNNNSVYLTNSKERMSPLKIRVIGKCSNPYWEVIQNSQIIATDGYFI
                     DMTETQTLEVSSLFEDTTAILKDIAGVESSVYQQQDYTKTNFVQAPTGEFSIVFHVGG
                     ADVEIELYEERDLF"
     gene            15345..16394
                     /locus_tag="L1U99_002060"
     CDS             15345..16394
                     /locus_tag="L1U99_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212595.1"
                     /translation="MILAVTLFHRDLMLYNEHLFSNSFEFGADEINEEASSFTMDKYV
                     PVKTGDFLLAKYIPSGKFAYFGVITSQEDEKISCKSLLSLADSEIPTARVSGDNYEEH
                     IRRLIEYYLLNDPTKQLKDILDVKAESATSHSYQATDTNKHKLSAYILNGFKKYNVKW
                     YFKGIQNRKIYTGIRAVNESIYIKDNSSEFSDWDVFVQAPGAGNENKLLIVDKAMKDI
                     EKPIILSTWYLDEENNLTQDGSKENITKPTVNLVNIYDQTAEDKASYEDVAKSELKGN
                     TYSHEIKVNVVRNAKNLNVETIETGMFATISYKGKIYKSVLTAWRISSDKEFVELTFG
                     NIRSRFMDYFEDNGG"
     gene            16398..17222
                     /locus_tag="L1U99_002061"
     CDS             16398..17222
                     /locus_tag="L1U99_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212596.1"
                     /translation="MVSNVDGYQFENVKVSAENDARLYHVLYNRKNQVIDGYDQSMNL
                     SSSGLTVKVAAGAAIIQGRMVVVRQEESITVPANSSGYIALTVDLTQEVIPGSILPES
                     EEYEWTNNQVKLEFITKVIKGNLNNGDKVYNLPLCSVTSTGSTVSISKISDSYELTLS
                     KGEILWSGTALMHDTQTVQPSKKMWQTVSGFLLVWLPYENGQAIGDRYVTTPFYKERV
                     TFTNVLGEIVSGFDDYHKKWFSKRINYNSNTNIFTGAASNASGDNANMVLRYIVSF"
     gene            17240..17785
                     /locus_tag="L1U99_002062"
                     /pseudo
     CDS             17240..17785
                     /locus_tag="L1U99_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176405.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
BASE COUNT         6339 a         3150 c         4129 g         4712 t
ORIGIN      
        1 tggattaagg aggaagagta atgcatatag gagataagat acataaattg agacggctta
       61 ataacgaaac aatgaacgac ttagttaaac aaaccggact gtcaaaatca tgggtatctg
      121 atattgagtc tggaaaaaag caacgcgctg actttaataa gatatgtgca atagccaaac
      181 attataaagt tagcttagaa tactttcagg atgattattt ggatagtgat gaacacgagg
      241 atattattcc tttgacagac gaaacaagag ttaaatcagt gaaatcgctt gaacaaagcc
      301 taaagtatct gaataacaaa caagaaccta accttctaga gatcaaacta aaagatactg
      361 actcagtacc agaggtttat tacaaaggtc agaagttaga gggattgata gatgtaagct
      421 atcactacca tacaacaact gatgtggtag ctggttcaac aaacgacatc aatatggagt
      481 acctaggtga agtaactaag tatccagata taaaaacaat cggacacaag agagatgtgt
      541 aaatgaaaga agctagacct agagacgaga tagacaaact atacaagacc aaacgatggc
      601 gagacctaag gcaagtagta atagctaggg acttcggcat gtgccaagag tgcaagcgtc
      661 gagggcggaa cacaaggggc acgatcatcc atcacatagt cgaggcgagg gaagacctgt
      721 cactgttctg gtccgtagat aaccttgaat gtatctgtgt agcttgtcac aacagagagc
      781 atccagagag atcaggcggg aagaagaaac caaaacctaa atcacatatc gttaaaatgt
      841 attcaactcc tgaaagataa gtttgcagcg aaatgaaggt agccccccta ctctaaaaga
      901 ttaaagagta aggcttgaga agaacggtgc tgtccttcct tcgtaaaaag accgcttttc
      961 aagttttttg gagaaaaagg aaaaagccga ccaatttaag ccggctttgg acgaagctat
     1021 ttcttagtcc atttgtttcc tttttgagaa gtaggaggta atcggtcgcc tggatcaatt
     1081 tttacttctc gtccgccttg gacatttcca ccacgaggtc ccacttcttt ataggttcct
     1141 tttggtttat tgtcttcgcc gggtttatag agttctccca taggaatccc tccctaaaaa
     1201 aatttcggca cagcactgcc gataacttaa ttataaggat tgtgataacg atttcaatat
     1261 atcttttgaa agaaggtgat attatgccgc aaccagcgaa gagtgcaaaa ttacaattat
     1321 taaacggaaa cccaaataag aagaataccg aagaactccg caagcgagcg gccgcagaag
     1381 acaaattaaa aatggctact gacaaaatca aaccgccgtt atggctagat tcgctaggaa
     1441 aggatacctt tgagtttatc gctgatgaat tgctgtctgt ggatttaatc agtaatccgg
     1501 acgtccatac aatggctctc tactccaatt ggtattcgca atacgtttct ttagaaaaac
     1561 agcttcgaaa actacaacga gagtacaagt tgaactatgc gcttgcgaaa aaggaggcag
     1621 aggcgagagg tgagccgttt aatgaaccta atgaattaat tggtaatccg ctctctcggc
     1681 agatggatac agcgtcgcgg aatctccgtt cttttggcgc tgatttagga ctatcaccag
     1741 cagccagagc taagttagct attaagatgg ctgatgatgg tggtgatgac gatgacgact
     1801 tctaatattt tggatatgtc ctacacagaa cgtgtggact attggcaaag ctatcttgag
     1861 gagcaagctt cttggggtgg ctttttaaaa tgtccatatc cggaattgtt aactacttgg
     1921 tatgcggaac gattaatcga tggaagcata ccagccagca aagaaaatat tcaagctgct
     1981 aaacggcata tgcgtgattt gcagcgccaa ggaacagatg attttccttg gatctttgac
     2041 gaagaaaaag gtcaccggcc tattagatat atcgaaaaaa aatgtaaacc aactgaaggc
     2101 gactttggtt cgtttgtttt gcaaccttgg cagcatttca taattggatc catgtacgga
     2161 tgggtacatc gtgatacagg agagcgtcgc ttccgcgagg ctcttatttt tgttggacgt
     2221 aaaaacggta agttttgccg tttaaaaatc gggcaaaatc ggtgaaaacc tttatttttg
     2281 gctttctttt agtaataatt cgatagcttt atcaagcaat ttagacatag gaaccatagt
     2341 ttcttccgac atttttttta atccttcgta taaatcttta tcaattgcgt tagaaattct
     2401 aattctgttt tttagtccgt atttgtccat gtgtgacact cctttttatt ttactataac
     2461 atccgattcc accgcttgca actaccatca attgatggta gtatataaaa gaggtgagta
     2521 gattgaaaaa atacattatt tacaaacact taaataaaat aaatggcaaa atttatatcg
     2581 gtgtcacaaa tgatattggc agaaggtgga ggagcggtgg gattgaatat aaaccaccaa
     2641 agaacgaaac ccaacaccac agaagttttt ggaatgcaat acaaaaatac gggtgggaaa
     2701 attttgatca tttgattatt gaagaagact taacgatgaa agaagctttt gagaaagaaa
     2761 agttttatat tgaactttat gactcaacta ataagaaaaa aggttataac atcgcaaaag
     2821 gcggaaatgg cggaataata tataaagttc accccaaagg aatgctaggg aaaaaacaat
     2881 ctaaagaatt ttcttcaaat cacagtaaat gggcaaagaa ccataagaat aattgtatga
     2941 caaacggtga tgttgtatgg ggtgttactc acgaacaccc aaaaggcatg ttgggaaagc
     3001 accacagcaa agaatcaatt atgaaaaaga aagcatatag tggtgaaaat gctgtaacct
     3061 caaaaccaat tgtcgcaatt gaacgggatg gaactaaaag agaatttcac agcgctaagc
     3121 tttgcatggc ttactattcg attagtacat gtgtttttta ccgactttta aaagatggcg
     3181 ccccttatgt gataaatcct aaagcgaact acagaaataa agaaaaaata ttagctatcg
     3241 aaggaattat gttcaaacat aaagaagata ccgaggtaag ttagtagatt gcgaaaggtt
     3301 actaactacc gtaacgcgta ggagttgaat aaatataatg ctcccaagag tgtccgacag
     3361 cagataattt gctgaaaatg tacgctaaac tgggccagaa ctgactgacc gatgaaaatg
     3421 agggtgacct ccagagtgcg agataaaaag ctcgcagata ataacaatcg aaaacatcac
     3481 taatttcagg cctttccaca tacatggtcg cttatgatga tgaacaaggc gccaacgttt
     3541 acgtattggc aaatgctcgt gatcaagcaa gcttgttgtt tgataaggcc gcagaaatgg
     3601 tcaaacaatc gccggcgctc tttaagaaat ttggtaagcc taaacgatca agtattaatt
     3661 atgctcccgc cttttctaaa atggaaccac gcgcctcaga tagccggaaa ttggatgggc
     3721 taaacactca ctttggtatt tttgacgaga tccacgagtt tacgaattac aatctgatca
     3781 acgttatcaa gaaatcaaga ggaaccagaa aacagcctct gatagtttat atcacaactg
     3841 ctggatatgt attagatggt ccgttgatgt cttattttga gcaaggtgtg gactgtttgg
     3901 aacatttgga agatgacatc gatgaacgga ctttctatta tctggcaaaa cttgacagtg
     3961 cggaagaggc tgatgaccca agattatgga tcaaagccaa tccgaatatt tgtctaatga
     4021 attttgttgg catgctagat gactatgtta aggataaaaa agatccaaaa gaatatgctg
     4081 actggattac caagcaattt aacttgtttt ccgatatcga tgagctgtca tttgtcgata
     4141 tgcctaccat taaacgaaac aataaaacca tcgatattga aacgctcaaa ggtaagaagt
     4201 gtgtcggtgg ttttgacttg tccgaaacgg aagactttac cgcagccgtt ttagaatttc
     4261 cgcttgaaac aggcgaggta ttcattttgc aacacacatg gatcccacaa gctagatttg
     4321 atcgagataa caatcaagag cgtatcaaag cgtgggagaa ggtgggagat ctaacgatta
     4381 ttcctggtga ttacgtcaat tatgaatacg tcttaaattg gtttgtagaa aattcgaaaa
     4441 tctatgacat tgtaaaaatc aattatgaca aggccaaggc gctacgatta aataaagaac
     4501 tagaaaatgc aggatttgaa accaacgaga ttcggcaagg gtttctatca ttaggtgggc
     4561 caatgcaaaa cttcaaggaa atgctattgg acggtaaggt gattttcaac aattccaagc
     4621 tttaccgatg gtatctatcc aacgtcaagc tggtgatgga tcgcaactca aactggatgc
     4681 cgtctaagca gtccaagagt agaaaaatag atggttttgc agcaagtttg aacagccacg
     4741 ccgaagtgtt gaatatgttg gttaatcctg tcggaaccgg gaaagtaacc tattactcga
     4801 tttccgattt aatgaatatg taagaaaggt gtggaggaat gagtatttta gatcgtttgc
     4861 gttcttttgg ccgagcgaag ccgaaagcga gcaaacaaga gtattttttg aatgacccgg
     4921 gattgatacc gtatttagtc ggaaaagatg aaatatcaga agggattttt tccgtaatta
     4981 gccgtgtatc gaacgttttt gcgtctctcc ctctcaaaat gatagatgcg gagtttggcc
     5041 aaccggacga ctgtcctgca tacaacttgt tgagcgaagg ccctcgatat tttacaaagt
     5101 ttgatttttt ccgggacgtg gaagttttga gaaactacca agggaatgcg tatgtgcaga
     5161 ttttccgaaa tatcaatgga gaagtagcag atatggcgtt aataaaacct ggtgcttgcc
     5221 atccagtgat tgatatggat agcggggagc tttactacca agtaactgcg actgacaaag
     5281 gcagttataa gcaagttatt tatgtacatt acatggaaat gctccacttt aaacaaccga
     5341 ggtttggtgg cttggaaggt acagacccca caaaagtatt aacgaatacc ctcggatatg
     5401 atcgagaagt ccgaaaaatc tctttaagtc agcttaaagg aggtaatgaa gggctaaaag
     5461 ttaagtttgc tagcaatgtg gatgaagaag ctaaaaaagc tacagttaaa aacattgctg
     5521 atttttatcg acaaaacggt ggactacttg tggaagaaaa cggtgtagaa atcgaacgtt
     5581 tacaacgaga gctggtagac agcaagcttt tagatactga taaagtatct cgctccagaa
     5641 tcgcgatggt ctacaacgtg ccggaacatt tcattgggag taaccagtcg agttactctt
     5701 cacaggaaca gctcaatatg gagtttttga catacaatct agtaccgacc gttaatcaat
     5761 atgaagcgga actaaataag aaaacactat cgagaaccga aaaagcaaaa ggttatcgat
     5821 ataagtttaa tgtcgcaagt ttgctaagag ctgacactca ggcaaggggg caattctatc
     5881 aaatcatgcg acgaggcgga gcatactcag cgaatgatgt ccgaagattt gaggacttgc
     5941 aaccgataaa taaaaccggt atggatgatt atcatatttc cggagaccta tatccaatcg
     6001 atatggatcc aacattaaga aaaacaaact cgtctaaaag cgtagccgaa aacggttagg
     6061 cttttttagt ttgcaccgaa gggaggtgaa aggatgaaaa aagtgacgtt aagcggcgat
     6121 gtcgtggata acgataccgc gtggttatat gactggtttg ggattgattg tatctcacca
     6181 gggaaaattt ctgccgctct tacagaagca gcgggggatg aagtagaact tgatatctca
     6241 tctaacggtg gggatgtcct agcggcaagc gaaatatata ccgctatccg tgcctatccg
     6301 ggaaaggtat ccggaaatgt tgtgagtatt gcagcaagcg ctgcaagtgt aatcgcttgt
     6361 gcttgcgaac cgcttagaat ctcgccaaca gcacacatca tgattcacaa cgcatgggtg
     6421 accactagcg gcaacgccga ggaattaaaa gccaatgcgg aaatgttaag cagtgtggat
     6481 gagtctatcg ttaatgctta cgagatcaag acaggactcg accggaaaaa gcttgctgat
     6541 ttaatggcaa aagatacttg gttaaacgca caaacagcag tggcggaagg ttttgcggat
     6601 gaaattatgt ttgcagaagc accagtaacg gtactcaatg cctctcaacc ggttattcca
     6661 aaaaacgcgg taactaagtt gaaaaatcta atactcaaag cggaaacacc gcaagaagaa
     6721 acgctcttgc agaaaaaact aaaagcctta aatggaggga aaaacgaatg aatttagaac
     6781 aattaaaaaa tgcgtgggtc gaggcgggaa gtaaagtctc tgatttaaac gcgcaactca
     6841 atgcagcatt ggttgacgat gaaaaaacag aagaagatgt agtaagtttg caagcacaag
     6901 taaaagcagc acgggctaaa cgggacggat tgaaagagca agtggcaaat atggaagccg
     6961 aacaagtctt aaacgtcaaa aaagaaccat tagataaaaa agatgaaaac ttgaaaaaca
     7021 agtttatcaa agactttaaa gcgatggtca atggtgatcc tgctattatg gctactttga
     7081 catctaatac ggatgaatct ggtaatgcta tcggattgac tattcctgta gatgtgcaaa
     7141 cgactattca tactttggtt cgtcagtttg actctttgca agaatacgta aacgttgaaa
     7201 aagtgaccac tactagcggt tctcgggttt atgaaaaatg gtctgatatt aacccactga
     7261 ccgctttgga tactgaagac ggtgaaatcc cagcaaatga tgatcctgca ctttacttga
     7321 tcaaatactt gatcaaacgc tacgcaggta tttctacagt aactaacagc ttgctaaaag
     7381 atactgccga aaacattttg gcatggttgt ctaactggat cgcgaaaaaa gtagttgtta
     7441 ctcgcaatac aaaaatcttg gcagctattg atggaatcaa agcagcgcaa aagaaagatg
     7501 ttacagatgt tgatgggatt aaagatatca taaacgtcca acttgatcca gctatcgaag
     7561 ctacatctat gtttattaca aaccaagatg gcttcaatgt tttagataaa gtgaaacgtg
     7621 ctgatggatc ttacttgtta caaaaagacg tagcttctgc aactggatat accttcttag
     7681 gtaaaccaat caagaaaatt gcttctcgtt tcttgccaaa caaaggtacg caagctactc
     7741 ctaaatatcc actgtatatt ggtgatctga aagaagctgt tacattgtat gatcgcgaaa
     7801 acatgagctt gctgacaacg aatattggcg ggggggcttt tgaaacagac accaccaaag
     7861 tacgggttat cgatcgattt gatgtgcagt tagtcgatga tgaagcagtt gttttagcta
     7921 catttacatc tatcgcaaac gaagtgccag taacaaacgg ttaaggagct gatttcttat
     7981 gattcttgat cctaaaatgg atttagacga aatcaaaaac gcactaaaga ttgataccga
     8041 tgatgacgat gtggaagtaa gacgtgcggt gcaagctgca attgcataca ttagaggggc
     8101 tatcgggaat gataagccct ctttttataa gcaagaaaat gacacggttg atctgattaa
     8161 tttagctatt ctgcaattag cagatcatta ttacaacgct cgatcagcaa ccgtgagtgg
     8221 gaacttgcga gagtacgatt taggttttac aagcctaatc ttgcaactca aagcaagata
     8281 tttgcttttt gtggaggagt agcgtatgcc ccttattcaa acaggaaatt taaatcaacg
     8341 catcaagttt gtccgagata cgacggtcaa ggacgaggac gggcaagttg tccggacttc
     8401 tacaaccatt cttacttgct gggcaagtgt gcagacacaa cgcctgaacg atattaagac
     8461 gtccattggt acggctttgg aaggaacact gacgttcatt atccgctatc aacaaaaatc
     8521 agagctaacc aatgatatga aagtgcgttg gaatggaaaa acgtttgaaa tcattacgat
     8581 tacgaaaggc gagtttgcga aggacttcac gacaatcatt gcaaaagagg tttcaaaatg
     8641 agtgtagaag tcgatgcaac cgaagtgtac aaagcgctta gggaagtaaa agcaaacgtt
     8701 caacgagtgg aaagcccagc acttagaaaa gctggggagt acgctcaaga aaagttacaa
     8761 caaaacacac cttactggga tggaacgaag tcaaacggta aacgtggttc gtatatgcaa
     8821 gaacatgcta aggaccatgt ggttacaagc tcggtaaaaa acggattgat agaagtcggc
     8881 tatgataaag atgtttcttg gcggatgcac tttatcgagt tcggaacaat caaacaacgt
     8941 ccaaaaggtt tcgtacaaaa aacacaaaag caaatcgaaa aacaagtaac acaaatcatt
     9001 gctgacgaag taaaaaggag gctaggactt tgaaaacggc agtatcacaa gtctattcaa
     9061 ttctgaatag caatgaaaaa acaaagaaca ttgattttta caccaatagt gttccggaat
     9121 cggctcaaac agtacctagc cttccagttg gcagaattac agagatattc ggcaactatg
     9181 aagatttcgc aagcaacaat cctttgacca ttcaatttaa cgtacaggta gatgtatggg
     9241 tatcgacctt aaaagaggtt gatgcctttt attttgccct tgatgagatt atgaggggga
     9301 atggttggca atgcgcatac acggaacaaa cagatgatga ggatttagaa ggtgcaaagc
     9361 ggattatcaa acgatatgta gcaaatattt cactaaatta aaaggagaga aaatagatgg
     9421 caacagtagg atttgagagc gtcatttttg gcgtaaaaac aggtgcaggc ggcactctaa
     9481 aagaattagt agcagataag tcgaaaggcg gagcgatcga agctaaaatt actggattag
     9541 gcgcaacttc taacacaaca tacgcttcaa acgtaccatt cttcattgca agtaaagggg
     9601 tttcgtcgcc aaaagttacg cttgacgtgg cagacttaat ggataacggc atttacagcg
     9661 aaatcattgg cgctaaaacc gtggatggtg taaatgtaat tggttcagaa actgaagcgc
     9721 cttacgtgtc ggtagtcatg gttacagcga acaaagaagg aaaacgctta ttcatgggat
     9781 tggcaaaagg aaaattcagt catccagata tcgacatgaa aacagctgaa gacaaaggag
     9841 ttgaattgca aaccgattct atcgaagggg aattcatttc tgatgaacgt ggctatgtat
     9901 acttaacagc cgtagaatca gaagaaatga ccttacaaaa attcaaggac ttggtaaata
     9961 acaaagcggg ggagtagtta accctgcatc tacaccaacg acagatacag ggacaccaaa
    10021 agaaccagaa ccaaaaattg atacacaagg ttagccattt tttggctagc cttatttttt
    10081 tgtaaaaaca aggaggaaaa caaatgattg aattgcaatt gaaacttgac ggaaagaaaa
    10141 aaacattcaa acaacaagat atttccgcac gtgcaatgcg tgagtgtatc aaattttacg
    10201 agaaagcgga aaaagcagac ctaactgatt tagaagcaat tgattcaatg attgcaatta
    10261 cagcagatat tttccaagat ccagcagtta catttgatgc tattttagac ggtttgactg
    10321 cgagcgagtt agtaccggca ttagaaagtg tttttgaaca aatcaatgaa ctgggaaaca
    10381 atgaaaaaaa gcagacggcg agcaaaaaga gataagtttt tctgaagcta ggaaagcaat
    10441 ggatcaaatc tacaaagatt taatcgaatc aggttggacg atgagagatg tggacgaagc
    10501 cgactatcat tatttgttac acctttttgg agaagtggag agtggcgaag aatatgtaga
    10561 tggtgctgat ttcatcaaac aatttttatc ggctgaagac ttggtaaaac ttgaggaagg
    10621 aggtaaataa tggcaggaaa aggacaaccg gcaggaaata tcaagctagg gattagttta
    10681 gatagcacta attttggtaa cacgctggac gaaatcaatg cgaaagtcaa acaagctgag
    10741 tcgaatatgc gtgccaatct aaaggcttat gattcagcag gacgttcata cgaagcactt
    10801 agtcaaaaga cgaaagactt gtctacggtt atggaagggc aaaacgccaa agtaagagaa
    10861 ttaacaaagc gccgtgatga agcgattagc aagtatggcg aggaatcgaa acaagttgct
    10921 aaccttaaca cacagataaa caatgctacc gcaaaatata atgcttacag tcgccagttg
    10981 aatgacacaa aaaaagaatt ggtgtattcc aaaacagccg tcaatgattt atctaacgaa
    11041 atcaaagaaa atgaacgaca aatgaacgcc gaagtaaaag cgttgaaagc cgctggtgat
    11101 gaatctggtg cgtttgaagc aaaacaaaaa gggctagcca aacaaacgga attatccgag
    11161 aaagctatcg aagaacagcg caaagttgtg aaactgatgg ctgatgagtt tggcgattca
    11221 gcaaatgaaa ccgaagatgc aaaaagggca ttagaaaagt tagaacgaca aagccaaata
    11281 tctagcaggc aattagaagc actcaaaagc tccagcgatc aatcaggaaa aaaaatagaa
    11341 gattttggcg acaagtccac aaggtcagct aggaaactgg atgggctaaa agacaaatta
    11401 ggctcgctaa aaagcgcatt ttcgtttggt gcagttgctg gattagcgca taacgctatt
    11461 agcagtgtag taagtggcgt gcaaggcttg gttggcgaag cagtaaacgc atcggattca
    11521 ttgatgaagt tttccaaaac catggagttt gctaactttg ggaagtcaca gatagaaagc
    11581 tcgaaaaaag aaatgaaaga ctacgccgat aagacggttt atggtttaga agaaattctg
    11641 aacacaaccg cacaattggc atctaacggg attcctaact atacagaact aaccaaggcg
    11701 gcaggtaact tgaatgccgt tgcaggcggt tctagtgata cattcaaatc cgttgccatg
    11761 atgctaacgc agacggcagg agctgggaaa ctaacaactg aaaactggaa tcaattagca
    11821 gatgcgatac cgggcgcttc agggctgtta caagacgcta tgttgaaaaa cggagcttat
    11881 acaggaaact tccgtgatgc aatggcgcaa ggtcaaatca cttctgatga gtttaaccaa
    11941 gcgattgtac agttaggtat gaatgacgga gcagttaaag cagctacttc cacagataca
    12001 ttgagtggtt cttgggaaca gatgaaatct actgtaataa atgggttaca aagtatcata
    12061 gacaaagtag gcgttgaaaa tatcactggt ttcatcaaca gagtaacaaa agggattgaa
    12121 aattctattc ctaaaattac tcaatttata ggttggttga gagatattgg aacgtggatc
    12181 gttgaaaata gagagccact aacatggatt gtcggaatca taggcggaat tacattagca
    12241 gtaaaagcat tgaacgtagc aagtatgttg ctggcaatta ctggcggaac attggcagcc
    12301 ccttttgtgg cgattggtgt agcattaggc gcactagcag gtgctttggt gatagcttat
    12361 acaaaatctg aaacatttag aaatatagtc aatgcggctt ttacagctgt gaaaaacgta
    12421 gttatgagcg ttatcaataa tttggtggaa tactacaaaa tgttgtggag cgtgttgcag
    12481 tggctttggg aaaaaataaa agaatgggct tcatggattg gcaataaatt cattgaaatg
    12541 aagaacagcg ttgtgaatac ggttcagaac ctatggaatg gtgtgaaaaa cttcttcagt
    12601 aatggcgttg gagacacttg gaataaggta gttggctggg taaaaaacat tttcaacaaa
    12661 gcaactgaat tgaagaacaa agtttctgat gcaattggta acctgtggaa cggtatcaaa
    12721 gacacattcc gtagaggcat tgatacggta ttcaattggt tttcagaact accgacgaag
    12781 atgaagaatg ccattattgg cggtaaaaat gccattgttg atgcgttcaa aagtattttc
    12841 aacgcagcac ttaaagcgat aggtaaacca gttaacgcaa tcatccatgg agcttcatgg
    12901 gtactagaaa aactgggtgc tgacaaactc gaagaatgga aagtgccaca atacgcaaaa
    12961 ggaacaccaa acggaggtca tccgggcggg cctatgatgg taaatgacgg tagaggtgct
    13021 gaagcggtaa tcacacctaa cggacaagca tttatcccac gagggcgaaa tgtagtgttg
    13081 aatgcaccaa aaggcacaca cgttctaaca gctgaagaaa cagcttatat gactggaaac
    13141 aaagcaccaa gatatagata cgccaaaggt acaggctttt tcggaaatct atggaacaac
    13201 gtcaaaggat ttgctggaga tgttggaaac aagctgaaag atgtagtcgg cgatgtatgg
    13261 gattttgtaa cagacccggg agcgttggct aggaaagtgt taaatggtct tggcgtactg
    13321 gaagggcttg tcaaatatcc tttagatgtt ggtaaaggta ttctaagcaa ggctaccgaa
    13381 gcattgacga acaaaatcac agaactattc agcagtggca gtttagacac ttcaatgggc
    13441 atgcaaggcg tttacaaata cttggcggac gttgcagttg cagtaatgaa gaagtttcca
    13501 ggctttgtgg caactagtgg gtatagacca ggtgacccct attcgcatgg taaacgtaat
    13561 gccattgata ttgcactacc tggtgtcaca ggaggctcgc cacgctacac agaagcagcc
    13621 aattacgcat ttgagaagtt tgcaaacaaa atcggctatg ttatcacaaa tggcaaggtt
    13681 cgtgaccgtt caggacaatc aggtacaggt attcacaatg attggagacc atggcccgat
    13741 ggagatcact atgatcatgt gcatttaaac ggtgtgaaag acccacaaaa cactcaaatt
    13801 tcaggagata gcgtgggagg cagtggggta gaaagatggc gcaatgtagc aattagagcg
    13861 ttgaaaatga ccggtcaata cagtactgca aacttaaatg cattactaaa tcaaatgcgt
    13921 acagagtcaa atggtaatcc taatgcagtt aacaattggg atattaacgc caaaaatgga
    13981 acaccatcaa aagggttgct ccaagtgatt gacccaacat tcagacagta tgcaatgcca
    14041 ggattcaaca gcaatatttt tgacccacta tctaacatct tagcttcaat cagatacgca
    14101 ctatcaagat atggctcact aacaaatgcc tatcgtggag ttggttacgc aaacggtgga
    14161 attgtaaacc aacatcaaat tgcggaaatc gcagaaggaa acaagccaga aattattatt
    14221 cctttagata aggctaaacg atcaagagcg atgcaattat tgtctatcgc aatggacaaa
    14281 ctaggagttt ctcctaaaac ttatggaaat gcgacaactg tttccagtga ttacgaaatc
    14341 ctagaagcca ttgaaaaaca ggcggcaaca acgaatcagc tgttatcgtt attgctggca
    14401 tttttcaaag gaaatagccg aactgataga gatttagctt tagatattca gaagatcttg
    14461 gttaggagga tgtagatgcg aactgtatta ctgagaaata gaataaacga agaaattgat
    14521 ttgtctacgg aggattattt tgctactggg ttgagtaata tggggtttga agtaaaaaaa
    14581 gaacatgtgg gacagtgggg gaatttcaga gaaagcagtg agaacgttga aatatctgaa
    14641 tttcagtcat ctgtaatcat ttctgtgcat gggtttcgag aaaaagaact gtacaattca
    14701 cttgtgcagt tcctatcgga aggtccgttt gaactggaat ttgcttttga cggcgaaaca
    14761 atggtaagaa gatgcagtct aaaatcttta agtaagactg aaatcgatcc gaaaacatcg
    14821 ttactaacag acactttaga actatatttc acatcaaact ggtattccgt aaaacgcgaa
    14881 aaattaattc agcgaccgaa tgtagtgaaa acacgtggta aggtttttcc gtataaaaga
    14941 tcttatatct acactcaaaa cttgtgggag aaaaaaggtg tattcaaatt caataataat
    15001 tctgtatacc taacgaatag caaggaacgg atgtccccgc taaaaattcg tgtgattggg
    15061 aagtgttcaa atccgtattg ggaagtaatc caaaactcac aaatcatcgc aacggatgga
    15121 tacttcatag atatgactga aacacagact ctagaagtat caagcctttt tgaagataca
    15181 acggcgattt taaaagatat tgcaggggta gaatcttctg tctaccaaca acaggattat
    15241 acaaaaacta attttgttca ggccccgact ggagaattca gcattgtgtt tcatgttggg
    15301 ggggcagacg tagagattga gttatacgag gagcgtgatc tgttttgatt ttagcagtca
    15361 cgctttttca tcgtgattta atgctttata acgaacattt attctctaac agttttgaat
    15421 ttggtgcgga cgagatcaac gaagaggcta gtagctttac gatggataag tacgttcctg
    15481 taaaaacagg cgattttcta ctagcaaaat atattcctag tggaaaattt gcatattttg
    15541 gtgtaattac gtcgcaggaa gacgaaaaaa tcagttgtaa aagcttactt agtttagctg
    15601 atagtgagat accgactgca cgtgtgtcag gagataacta cgaagagcat atccggcggt
    15661 tgattgaata ctatttgctg aatgatccaa cgaaacaact aaaagatatt ttagacgtca
    15721 aagcagaaag tgcgacctct cattcgtatc aagctaccga tacgaataaa cacaagttaa
    15781 gtgcgtatat tctcaatggt ttcaaaaaat acaacgtaaa atggtatttc aagggaattc
    15841 aaaacagaaa aatctataca ggcatacgtg ctgtaaatga atcaatttac attaaagaca
    15901 attcttctga atttagcgat tgggatgtgt ttgttcaggc gccgggcgct ggaaacgaga
    15961 acaagctatt aatcgttgat aaagcaatga aagatataga gaaaccgata atactgtcaa
    16021 catggtattt ggacgaagaa aacaatttga cacaagatgg atcgaaagaa aatatcacga
    16081 aaccaactgt caatttggtt aatatctacg atcaaaccgc agaagataaa gcatcctacg
    16141 aagatgtggc aaaatcagag ttgaaaggca atacgtattc gcatgaaatc aaagtgaacg
    16201 ttgtaagaaa tgcaaaaaat ttgaatgtcg aaacgattga aacagggatg tttgccacga
    16261 tttcttataa aggaaagata tacaagtcgg ttttgacagc ttggcgaata tcaagtgata
    16321 aggagtttgt ggaattgact ttcggaaaca taagaagtcg ttttatggat tattttgaag
    16381 ataatggggg ataaaaaatg gttagcaatg tggatggata tcaatttgaa aacgtgaaag
    16441 taagcgcaga aaatgatgct agactttatc acgttttata taatcggaaa aatcaggtta
    16501 ttgatggtta cgatcagtct atgaatttat cttcaagcgg attaacagta aaagttgctg
    16561 caggagcagc gattattcaa ggtcgtatgg tcgttgttcg acaagaagaa agtataacag
    16621 ttccagcaaa ctcaagtggt tatatagcat taacagtgga tttgacacaa gaagttatac
    16681 ctggatctat tcttccagaa tcggaagaat atgaatggac taataatcaa gtcaagctag
    16741 aatttataac aaaagttata aaaggtaatt taaacaatgg tgataaggtc tataatttac
    16801 cactatgctc agttacttct actggatcaa ctgtttcaat ctcaaagata tcggatagtt
    16861 acgagctgac tctctctaaa ggagaaattt tgtggagtgg gactgcgtta atgcatgata
    16921 ctcaaactgt ccaaccttca aaaaaaatgt ggcagacagt ttcaggtttt ttattagtat
    16981 ggctcccata cgaaaacggg caagcaattg gggatagata tgtaactacg cctttttata
    17041 aagagcgtgt aacttttact aatgttttag gagaaattgt ttcaggattt gatgactatc
    17101 acaaaaagtg gtttagtaaa cgaataaact ataattcgaa tactaatata tttacaggtg
    17161 cagcaagcaa tgcaagtgga gataacgcaa atatggtgct taggtatata gtttcttttt
    17221 agttaggagg tatggaagag tggcaaattt agaaattaaa ttatctgcaa ataagagaca
    17281 gccttatcta cgtcaccgtg ttgttggtag agttggtgat ggggggctca caacaatcaa
    17341 tgtacaactt cttgaggaag atgaaattac accttttgta attaatctaa acggtacttt
    17401 gaaatttgtg ggcgaagttt caaacggtaa ctataccgag ggagaaccag aaataatcga
    17461 ttcgactaat gggttaatta gttacacgtt cactaagtca aatttcagca cgagtcatca
    17521 attcaaacaa gcatattttg aatatgtaga tcctaacggc aaaaaagtaa cttttcagaa
    17581 cttcatcata gacgtgttag aacgagtaga tattaattcg gagcaagcga aatactatat
    17641 ttcttcattg gaaaaattac agagtgaaat gcaaaccact ttcaatcagt tcattagtga
    17701 taaacaggtc caatacgatc aaatctactc gaaatataac gaattagtaa gattgataaa
    17761 tgaatcagat aagcaagtaa atgatcgtat tgataagaca aatgatcgta ttgatcaaac
    17821 caatcagcaa atcggcgatc tcggcaagct gaaaaagatg tacagtaaca gcatcgactt
    17881 cggggactat gattatagtg ggaatccgaa ccttagcgct aaacttaatg cttcaagttt
    17941 ttctttaggt actggcgcaa cagtcgcgga tgataatgat gagattgtgt ttaccttaga
    18001 tggcacaaat caactatcga agtacgctag caaagcgcaa gtgccggtag cagaagggaa
    18061 acaatatacg attagttgtg aaattatgtt agaagatggg ttcactggcg acccttcagg
    18121 aatacgtctg caacacgcat atttgccagg cggggttgtt gttttacaga cagagacagt
    18181 acctaaaaat gaattgaata cgtggcagac gcttatcgga acgcgaacgg taaaatacac
    18241 ctctgacgta ccaaatgaat ggtacccttt gtttagagac atccgaacac ttaaaccgac
    18301 cggtaaagtt agactaagaa aaattaagat
//
LOCUS       DAFLVO010000058        17819 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.058, whole genome shotgun sequence.
ACCESSION   DAFLVO010000058 DAFLVO010000000
VERSION     DAFLVO010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17819
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.058"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..135
                     /locus_tag="L1U99_002063"
     CDS             <1..135
                     /locus_tag="L1U99_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1212597.1"
                     /translation="FNQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA
                     "
     gene            complement(313..2310)
                     /gene="tkt"
                     /locus_tag="L1U99_002064"
     CDS             complement(313..2310)
                     /gene="tkt"
                     /locus_tag="L1U99_002064"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBN1212598.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2412..2663)
                     /locus_tag="L1U99_002065"
     CDS             complement(2412..2663)
                     /locus_tag="L1U99_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HBN1212599.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2810..3433
                     /gene="lexA"
                     /locus_tag="L1U99_002066"
     CDS             2810..3433
                     /gene="lexA"
                     /locus_tag="L1U99_002066"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBN1212600.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3613..3831
                     /locus_tag="L1U99_002067"
     CDS             3613..3831
                     /locus_tag="L1U99_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212601.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(4120..4632)
                     /locus_tag="L1U99_002068"
     CDS             complement(4120..4632)
                     /locus_tag="L1U99_002068"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBN1212602.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4646..6943)
                     /gene="recJ"
                     /locus_tag="L1U99_002069"
     CDS             complement(4646..6943)
                     /gene="recJ"
                     /locus_tag="L1U99_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBN1212603.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(7085..7528)
                     /locus_tag="L1U99_002070"
     CDS             complement(7085..7528)
                     /locus_tag="L1U99_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HBN1212604.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7529..8317)
                     /locus_tag="L1U99_002071"
     CDS             complement(7529..8317)
                     /locus_tag="L1U99_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1212605.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8314..9255)
                     /locus_tag="L1U99_002072"
     CDS             complement(8314..9255)
                     /locus_tag="L1U99_002072"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBN1212606.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9431..10018)
                     /locus_tag="L1U99_002073"
     CDS             complement(9431..10018)
                     /locus_tag="L1U99_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HBN1212607.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10239..11546)
                     /gene="obgE"
                     /locus_tag="L1U99_002074"
     CDS             complement(10239..11546)
                     /gene="obgE"
                     /locus_tag="L1U99_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBN1212608.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11840..12850
                     /gene="gap"
                     /locus_tag="L1U99_002075"
     CDS             11840..12850
                     /gene="gap"
                     /locus_tag="L1U99_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBN1212609.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12935..13870)
                     /locus_tag="L1U99_002076"
     CDS             complement(12935..13870)
                     /locus_tag="L1U99_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1212610.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            14056..15015
                     /locus_tag="L1U99_002077"
     CDS             14056..15015
                     /locus_tag="L1U99_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HBN1212611.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(15101..16195)
                     /locus_tag="L1U99_002078"
     CDS             complement(15101..16195)
                     /locus_tag="L1U99_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBN1212612.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            16384..17145
                     /locus_tag="L1U99_002079"
     CDS             16384..17145
                     /locus_tag="L1U99_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBN1212613.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(17260..17700)
                     /gene="fabZ"
                     /locus_tag="L1U99_002080"
     CDS             complement(17260..17700)
                     /gene="fabZ"
                     /locus_tag="L1U99_002080"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBN1212614.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
BASE COUNT         5141 a         3871 c         3110 g         5697 t
ORIGIN      
        1 ttcaaccaag tcaatcaagg attcatctca tccgttgcgt ccaaaagaaa ccatatccct
       61 agaaaatcac taaattacca aacaccatta gaagtttttt tgagttacgt aaatggaaag
      121 ttttgtctcg cttaatttga caaataatat tctcaagaaa cacaaactaa tccgaagaat
      181 tctttgtttt gtcatttaaa tgtaacatag ccgaaaacga aaagtaatat tgatttattc
      241 ttctaacaca taaagaacag ctgtctccaa cttgcagaca gctgttctta tcagtcaaac
      301 aattgcttgg atctatgata gttgattgta cgtattcacg acattttcta ctgtaaatcc
      361 aaattcttct aaaattttag tgccaggggc agatgcaccg aaatgatcga ttgtaatcgt
      421 tgcgccctct gttcctacgt agcgttccca tccaaatgat gcagcagctt cgatagccac
      481 acgtttcttc actgatttag gaagtacact ttctttatat tcagaagatt gtttttcaaa
      541 gaggtcaaag cttggcatag aaacaacaga aacatctttg cctttttcag ccaattcttt
      601 ttgagctttc acagccaaat caacttcaga acctgttgca atcaaaatac cttctggtgt
      661 ttctccttgt gatggagaaa gaacatacgc gccttttttc accatttcat ctgctacttc
      721 ttttgtagaa ggcaatactg gaaggttttg acgactcaat acaaggatag taggcgcatc
      781 tgttgtctcc atcgctactt tccaagcagc acgtgtttca tttccgtctg ccggacgaat
      841 cacttgaaca ccaggcatgc agcgaacaga tgctagttgt tcaatcggtt cgtgcgttgg
      901 tccgtcttct ccgacagcaa ccgagtcatg tgttaagacg taaacaacag gagtatgttg
      961 gattgctgct aaacgaactg ctggtcttag ataatcgaca aagacaaaga atgttccacc
     1021 gtagatacga gttccgccat gaagttggat accattcata gccgaagcca ttgcaaattc
     1081 gcggacaccg aaccagatgt tgcgtccttc ataatgttca ggagtgaaat ctttatctgc
     1141 agccaccatt gtattattgg aacctgacaa gtccgctgaa ccaccccaga agcttggtat
     1201 agctttcgat aattcttgga tgacttcttt acttgaaaca cggcttgctt gactgcttcc
     1261 aacttcataa gttggcaatt ctgcatccca gttttctggt agtttgccat caaaagcatc
     1321 ttcaaattgt tgtgctaatt caggataagc ttttttataa ttggcaaaca tttcattcca
     1381 tgcatcttca gctttttgtc cttcttctat catcgtttga tggaagcggg cagctacttc
     1441 ttctggaaca gtgaaatctg gatactccca accataaact tctttagcca tcttgatgcc
     1501 atcttcacca agaggagcac catgaacagc agatgttcct tctttaggag caccatagcc
     1561 gatgactgtt tttacttcga tcaatgttgg tttgtctgtt tcagcttttg cttcttcaat
     1621 cgctttagag attgcttcta ggtcatttcc gtctttcact aagatatgtt gccagccata
     1681 tgcttcatag cgagcaccaa cgttttctgt gaaagctttt gaagttggac cgtctagtga
     1741 aatatcgttt gaatcgtata aaacgatcaa tttccctagt ttcatatgac ctgccatcga
     1801 acttgcttct tgagataccc cttccatcaa gtctccgtca ccgcatattg catacgtata
     1861 gtgatccatc acattaaagt tttctttgtt atacgttgct gcaaggtgcg cttctgccat
     1921 tgccataccg acagccattg caatcccttg tcctaatggc cctgtagtgg cttctacacc
     1981 atctgtatga tgtacttcag gatgtcctgg tgttttagaa tcccattgac ggaattgttt
     2041 caaatcatcg attgtcactt gatagccagc taaatgaagc aagctataca acattgctga
     2101 cccatgtcct gccgaaagaa cgaaacggtc gcggtcagcc cagttttttg atgtcgttgg
     2161 atttactttc aggtgttttg tccataacgc atatgccata ggtgctgcgc ccatcggcaa
     2221 tccaggatgt cctgagtttg ctttttggac tgcttcaata cttaatgtac gaattgtgtt
     2281 aacgccaagt tggtcaattt tgtcaaacaa aataacccct cctattaatt taggtttttt
     2341 ttacctttat ttcttacact ttcattctat aagatgtcac acgaaaaagc aatctttttc
     2401 agtatttttt actaaaagtt gtcatttcgg ttgtgtaagc cttttttctt ttggatttct
     2461 tttaattttt ccggggtcac gtcattgccc tcaggatcga cgactttcat tccttcgata
     2521 tgatgacgca taccggaacg aaaagcttcc aaatactctt tgcgcaagtt gatttgttct
     2581 tgttcttcgg cttttgagag accattttcc ttctttttac gtgcaagttc attgatccgc
     2641 tctatttttt caggtgacag catgctcagc cctcctttta ctctccttca tattatataa
     2701 aaactgaaaa aaaaacaact agataaacta aataaaatac gaacattcgt ttgatttagc
     2761 gctttttata tggtactatt tatttatcaa gtgaaagaag gtgtaccttg tggcccgaca
     2821 aactgaatca agacaaatcg aagtcttacg atatatccat gaacaagtaa cccaaaaagg
     2881 atacccgccg actgtccgtg aaatcgggga agctgttcag ctttcttcta cttctactgt
     2941 tcacggtcat cttgcacggc ttgaaaaaaa agggtttatc caaagagatc cgacgaaacc
     3001 tcgtgcaatc gagttgacaa aacaaggttt agaaaagatt gggattcgtc caacaactat
     3061 tccagtactt ggcgtcgtaa cagctggaga acccatttta gcagtagagg atgcttcaga
     3121 cttctttcca atccctccta atctttcttc cgaagaaggc agtctcttta tgctgacaat
     3181 tcgtggagat agtatgatca atgctgggat attggatggt gacaacgtga tcgttcggaa
     3241 gcaagaaact gctcaaaatg gcgatattgt cattgcaatg actgccgagg acgaagcgac
     3301 ttgcaaacga ttctataaag aaaaaaactt tttccgtctg cagcctgaaa acgacttgct
     3361 cgaaccaatc atcttagatc aagtatctat attaggacga gtagtaggac tttatcgtag
     3421 tcatatctat taattgctac taattaaaag aaaacttttt aaaaagagtt tgagacgttg
     3481 gtctcaaact cttttttcgc ccgggttctt cttctttcaa atttttatca cttccctctt
     3541 tacaaaccga acaaatattc gtatactaaa tatacgaaca attgttcgca taaattaaag
     3601 aggtgagaat tcatgaaatc aatgagacgt cttggcttag tattaactgt tttgttttta
     3661 ggtattatta ttggtaattt cggcatacgt ccagctttac ttgtgtttgt tccgttattt
     3721 actttgtggt tcatgttgtg ggatgaaaag aagtaccgtc aatctgagcg gcgcagaatt
     3781 catgaagatc atttctatca tgagccctac tacagatcca ggcaatcata ataaggattg
     3841 actgctaatt attcaaaaga caagaagtta aacttttacg ggggtgtgac aaaaatcggt
     3901 cacatccttt ttttcgaata aacggtgttc taaagccagt ttttcggtat taagtcaaat
     3961 tgcggaaaaa gtgatttttt aaacttctac tggtctttgc ttgtttccat ttataaaaaa
     4021 atagcgaccc tcaaaagtca gatagagaat ctgacttttg agggtcgctt taaaatcgct
     4081 tctttaagaa taacatcaag aatagcttct tttttctgct taatattcca ttaatgtaat
     4141 gatgtcatat cctttgattt tgtcgcgtcc atggagatcc atcaattcga tcaaaaatgc
     4201 gcagcctacg actacaccgc ctaattgttc gatcagttcg atcgtcgctt tgattgttcc
     4261 tccagtagct agcaaatcgt cacaaatcag cacacgttga cctggtttaa tggcatcctt
     4321 atgcaatgtc aatgtatctg ttccatattc taatccataa gtcacttcga tggtttctcg
     4381 aggtaacttc ccttttttgc ggactggggc aaaaccgact cctaactcat aagcaacagg
     4441 acatcctacg atgaatccac gggcttctgg cccaactacc atatcaattc gtttttcttt
     4501 tgcataattt acgatttgtt tagtagcttc ccgataagcg tcaccatctg ccatcagtgg
     4561 ggaaatatct cgaaacacaa ttccttttga cggatagtcg ggaatactgg caatataatc
     4621 ttttaaatcc actctttgtt tcctcctagg ttgttaacca tttctttatg gtaggaatat
     4681 cgctcaaaag caaaaattcc tcaactttga ttttattgag ccgtcgctgg tataatctgc
     4741 tctcagtcaa aggatgactt tctgggctag cgactttttg taaaacaccg ttctctattg
     4801 taacaaattt caattcaaaa aacacctgta tcataaaaat taataatttt tcagggatac
     4861 gcaaatattg agctattgct tttattttat gacgtatatc aattcgttct tgagaatgga
     4921 tcaatttaaa caattttgcg tactgttctc ttgtgcctac cccattcaaa taggcctcat
     4981 caggtgaaat ccccatcaga taaacacgat tgaatgaata agaccgaaaa acttctttca
     5041 gatccgctaa atcatctgga caatccataa caactagaga gtttggtttt cttttttcaa
     5101 ttattgcctt tacagaatct agtccttcga aaacaatcgc agcttcctgg ataatctcag
     5161 gcacgaattt caacgtcgaa gaatcaaatg ctaaataaag gctaccttcc gacgttcggc
     5221 tctgttcacg gaaacgtttt gcccgccaat caaatacttg cagaccaccc acagaaaaat
     5281 cagataccat cagctgcggt ttcttacgcc cgttccattc attgatcgaa agctttccta
     5341 ccacatctac ctgattattc agcagttctt cttcttgagt accaaaacca aaagcgaccg
     5401 catcaagctg actcgatgca tcggaaagga caaatttcag atgctgttgg tttgctccga
     5461 ttcttttgat attttctgct tggacttgtc gaaataaaaa ctgaggcaaa ggattatccg
     5521 taccaaatgg cgccaatagt ttcagctcat caattcgctc tactgttact tcatttggca
     5581 gcaatacttc atcaattctc aactcaggcc ctctcatcaa gtcaatttga tgatcgacta
     5641 tatattggtt catcttctcc tgtagtatag tgacattttc acttggcatc gttaaaccga
     5701 ctgctgcatg atgtcctccg aagtaagtaa ataaatctcg catctggtca agcatttcaa
     5761 aaagattcaa ggcttcaata ctacgtccag atcctttagc tgatccatct tcttttaaag
     5821 taaggacaag cgttggttta cccgtttcat tcattatttt cccagcaaca atgcccaaaa
     5881 cgccttcatg ccatcctcgg tttaccaata gatggatatg attctcctta ttgaccatcg
     5941 ctaatgcttc ttgtgttatc tgctctacga ttgcttttct ttcttcattg atctcattca
     6001 atttttttgc ttgaacggat gcttcctctt catcaaacgt cgcaagtaac gagacggcag
     6061 gacgtggatc gcccatccga ccgattgcat ttagtctggg agcaatcgaa aaaccgatcg
     6121 ttgtttcgtc tgcgtccctc atttttacgc cgctttcttc aaatagcgcc tgaagtccta
     6181 tccgttctga atgatgaatg gcatcgattc ctaatgaaac aaggattcga ttctcatcag
     6241 tcaatgaaac taaatcggcg atcgttccta tcgctactaa atccaaaaat tctgcaggcg
     6301 gttcttccaa taatgcagaa gctactttga atgctactcc gactcctgcc aaatctggaa
     6361 atggatagtg ccccgctgga tgacgagggt gaacaatcgc ataagcgtct ggtaaattct
     6421 caggtagttc gtgatgatct gtaatgatca cgtctacacc agcttgctga gcgtatgcta
     6481 ccgcatcatt tcctgctacc ccgttatcaa cagtgatgat caactggatt ccttcttcga
     6541 tcttttcttg gtataccgat tggtttggtc catacccatg ctcaaatcga tttggcagga
     6601 atacttctac ttctgcacca agtaattcca gtgtttcttt cattaccgtt gcactggtga
     6661 tcccatctgc gtcataatca ccgtaaacga ggattttttc tccactgatt acagcttctt
     6721 ggattcggct gattgcttta tccatatcgt gtatcagata cggatcatgt aattcttgtt
     6781 cctttggatg taaaaatcgg ttgatatcct tttcctcatg gtaacctctt tgccacagta
     6841 acttaccgac aaatggagat aatttcagtt cacggatcat ttggagaaag gattcagaag
     6901 gctctgtctc gcttaacttc caatcaaaat ttgcttgtct cactttctca ctcctaactt
     6961 agttattata gcaaaggaaa tcagcaaaaa aaagcagaaa gaaagaataa aaacagatca
     7021 gatccgctag acagatgttc agcaggacct gatcttttgt acgaccattt atgaaatatc
     7081 cctattagtc aaaataattg aagctttgtt tgggcgattg agttttttgt tcttccggcg
     7141 ctttcaattg actgatttgt gcggttttcg cttgtaactc cgcctgataa gcagcttcca
     7201 actccgcacg ttcgtttcta aactcgcgtt gctgttcttc ttttgcttct tcaattttct
     7261 tttgaagttc tgtttgatat tctgacattt cctgagtcag ctgtttgatt tgcttttttt
     7321 gctgccatag tgttgccgaa gcagtcaaaa atacaatcag tgcaccaatc agcgcagaac
     7381 cgatgatcac taagatcaat ggcgcagaaa aggaagtgaa gccaaaactt acaggaacat
     7441 ttttattgtt caatacagca aaaagaacaa taatcaaaac taaaacaaat ccaagaatca
     7501 cattgctttg ctttttcaat tccttcacct actttttgtt aaaaattccg ctggctaaat
     7561 aatcaccaat cgttggaaac agcgtataaa attttgatgc aacttctaaa ataaacggtt
     7621 gattgatttc ccgttttgga tgtctcatat tgcggacgat catttttgcc aacttggcag
     7681 gttctaaaac gatttgtccg actttttcca aatagcttcc gcttggatca gccttatcga
     7741 agaaatttgt ctcgattgga cctggattca ctgtcgtaac agctacgcca agtggtttca
     7801 attctaatcg caaagcgttg gagaagccaa ggactgcaaa tttcgtggca gaataaaccg
     7861 ttgattttgc agttgccatt tttccagcca tagaggcgat attaatgata tgaccttgtc
     7921 ttctttctgc catatcgatc gcaaattttt gtgtcaaaac catcattcct aagatgttga
     7981 cttcaaacat atcgtatgct tttccaaggt cgaatgtaag gaagtcttcg aaaatcccaa
     8041 aacccgcatt gtttaccaga atatcgacgc gcccgacttc ttccatcacc ttttcatata
     8101 attcgtccac gctttcagga ttgctgacgt ctaccttgaa agcataagcc tctttgccgc
     8161 tcaagcgtct gcactcgtct ctgacacctt ctacaaatgc cattcttcgt gcgcaactta
     8221 taacgattgc tccttgcttt gctgcttcat aacagatttg tgcgcccaga ccgcctgaac
     8281 tacctgttac taaaacaact ttatcttcta aattcatgcc tcttcctcct cgcgaaatgg
     8341 aatctcaatg ctatcaaaat ctttcataat cgtcgtgttt tcaaacactt cttgtgcttc
     8401 tttttcaagc tctaaagctg cttttcctaa atatctcgca ctgatatgag taagtagcag
     8461 ccgttttgcc tgcgcttctt ttgcaacttc agcagcttga tgagtcgtgg aatggaaata
     8521 gttgtgcgcc attcttgctt catctttatt aaatgtgctt tcatgtacca gaatatcgct
     8581 attttccgca agcacaacgg aattatgtgt ttttctcgta tcgcctaaaa tagtcacgat
     8641 tcgtcctttt ttatctggac ctacgaaatc ttttccattg atcgtccgcc catcttctag
     8701 ttggatcgtt tcaccttgct tcagtttgcc gtacagtggt ccagctggaa tacctaattc
     8761 ttttagacga tccacctgca attctccttt atgatcatgt tcaaccacac gataaccaaa
     8821 actgtcgatc ccatgattta gtttttttgt ataaacagaa aattgctgat cagtaaaaat
     8881 cggggctgtt tcatttagct caatgaattt cagcggataa cttaaacgcg tttgcgaaat
     8941 acctaaagag acttttatgt attcctctat cccttttggc ccgtaaatct ctaatggcgt
     9001 atccccacct tgaaatgacc ggctgctgat gagcccggga agtccaaaaa tatgatcgcc
     9061 gtgtaaatgt gtaatgaaaa ttttaccgat ttttctcgga cgaatagtcg ttcgcaaaat
     9121 ctgcatttgc gtgccttcgc cacagtcgaa caaccaaact tcattgcgct cgtctaaaag
     9181 tttcaatgct atacttgtca catttctatg ttttgcagga acacctgcac ctgttcctaa
     9241 aaattgtaat tccataatct acctgacttt ctttaagttc ctctttaatt ttagggtaaa
     9301 aagaagggat aatcaaccgt aagtcgagaa tgggttcaaa ttaaaaataa cgttctaaag
     9361 cgatagcgtt ttctttgaaa attactataa aaacagcagc gaacccgttt gagatcctct
     9421 gctgttttta ttaatttgaa gatccagaac tttcattgtc gttggaagtt tgcggatgtt
     9481 tgtccttcca agtcttttgt gcagcttctt tcgcatgatt ttcagcttct ttcgcatcat
     9541 gcacatcttt ttcgacatct tcataatcca agcgagtaat ttctccgcct aattccatca
     9601 ttaccaattg attcagtggg cgattgtcct cttcatcagc aatcaagatc agtcctgtag
     9661 ctccttcacc gattttattt cctacaaagt cgaacacggt ctgggcatct tttatttctt
     9721 tggcatcttg tgtcgcaccg atcattcctc cggcaaacca tcctaataaa atccctagcg
     9781 gaccacctaa tacaccaacc aacattccga ttaatccacc cgtagaagat ttgttattac
     9841 cggtaaagtc gataaaatct tctattttga attgatgtgt cccattagga tcatggctga
     9901 caactgccat ctgttctcct ttaatcgaac gaacagcatg taactttttg atttctgaaa
     9961 atgcctgata tgcctggctt tctacttgaa aatttaaaat gattactcgt ttgctcatta
    10021 aaaacgcccc tttcatacct tcttgttatt tattttacct ttaattgaaa aataagaaaa
    10081 gaaaagcact ctttttttcc aataaaatag ggctgtgaca aaagtcgtat cacagctcct
    10141 ttttccgaat aaacggcgtt cttgaagctg atcacttctg tcacaacctc ccttaaatct
    10201 gaatctatat tttttggtat ttgtttttat ttgcttgcct attcgacaaa ttcaaattca
    10261 aactcaccga tacgtacaag gtcgccatct ttcgcaccgc gtgcccgaag agcttcatcc
    10321 acacccatac cacgtaattg acgagcaaaa cgcatcactg tttcatcatg atcgaaattc
    10381 gtcatttgga ataatttttc gatcttctca ccagataaga tccacgttgc atctgaatca
    10441 cgatcgattt ggaactcagg accttctgga ttgaatccat agtgtacagt ttcttcttcc
    10501 agttcttctt cgtacaatgg gaattctggc gttacttcta acaaatctgc tgtagcattc
    10561 aataacgcgt ccaatccttg tcgagtcact ccagaaattg gaaatactgg gatgtcatca
    10621 gcaaattcat cttctttttc cttgttcagc tgttctttga atttcactag attttccggt
    10681 gcatccggca tatccatttt gtttgccacg atgatttgcg gacgctctag caagcgtaag
    10741 ttataagtag ataattcttt gttgatggca agatagtctt cataaggatc tcgtccttcc
    10801 atcccactca tatcgatcac atgtaaaatt actcgtgttc tttcgatatg acgaaggaat
    10861 tgtgtaccca gcccaacacc ttgcgaagct ccttcaatca agcctggcaa gtctgctgcg
    10921 gcaaaacttc tgccatcact tgtagtaacc attcctagat taggtacgag cgtcgtgaaa
    10981 tgataagcgc cgatttttgg acgagcagat gaaataacgg atagtaaagt cgatttcccg
    11041 acagatggaa aacctacaag tccaacgtct gccaatactt tcaattctag ttcgattttt
    11101 cgctcttgtc ctggttcacc gttttcagca atttccggtg caggattccg aggagaggca
    11161 aaacggatat tccctcgtcc accgcgtcca ccttttgcca caactagtgt ttgaccattt
    11221 tcaattaaat ctcctaaaag agcaccagtc tccgcatctc ggacagtggt tccttgtggt
    11281 actttaacat aggtatcttc tgaaccacga ccgtgcatcc ctttactcat cccattttca
    11341 cctggctgcg ctttgaaatg gcgattgaac cgaaaatcca tcaatgtacg taacccttca
    11401 tcgacgatca agatgacatc gccgccacga ccaccgtctc cgccagccgg tccgccgtca
    11461 ggaacgtatt tttcgcgacg aaatgcaacc attccgtctc cgcccttgcc agctttcaca
    11521 tcgatcgtta cttgatctaa aaacatggac ataattaagt cctcctatta ttcatttatt
    11581 tatttgactg cctgaatttc cacaataaac aaaagtctta cttattttat cggtgaaatc
    11641 tgattttgtc tatcatttca gcaaaaagat tgtttacctt cttctttttt tatcatttgg
    11701 taaggtttcc aacctttttt ctgctaccaa gtataatttt ttgacaaaat attctttgcg
    11761 tagcagaata acagtgtatt aattgtatta attgaggatg ccgtttcaca gcacccctaa
    11821 taaaggagga acttttgata tgacagtaaa agtaggtatt aacggatttg ggcgtattgg
    11881 ccgtctggct ttccgccgca tcaaagaagt ctcagatgat attgaagtag tagcaatcaa
    11941 cgacttaaca agtccaacta tgttagcaca attattgcaa tttgactcta ctcatggtac
    12001 ttatcctggc acagttactg caacagaaga ctcaatcgta gtggatggcg aagcaactcg
    12061 tgtttatgca gaacccgacg caagcaaaat cccttgggca aaagaaaacg gtgtagatat
    12121 cgtactagaa tgtactggtt tttatacatc tgaagaaaaa gcaaaagcgc atttagatgc
    12181 tggtgtcaaa cgagtagtta tttctgcccc agctggtgct atgaaaacca tcgtctataa
    12241 cgtcaatgat gatacattag atgaaaacga caaaatcatc tcagcaggtt catgtacaac
    12301 aaactgttta gcacctatgg cttatttctt aaataatgaa tttgggatcg aagttggtac
    12361 aatgacaaca gttcatgcct acacttccac acaaatgctc ttagatggac ctgtaaaagg
    12421 cggtaatttg cgtgctgctc gttcagctgc tgacaatact atcccacatt ctactggtgc
    12481 tgcgaaagca atcggcttag ttatccctga gctacaagga aaattacaag gacacgcaca
    12541 acgtgttcca gtcgttgatg gttcattaac tgaattggtt tcagtattga aaacaaaagt
    12601 aactgctgat caagtaaacg aagcaatcaa aaaacacaca gttgacaatc cttcattcgg
    12661 gtatgatgac cgtcaaatcg tttctagcga tgtcattgga acaactcaag gttcgatctt
    12721 tgacccaacg caaacagaag taacaactgc tggtgatttc caacttgtta aaactgttgc
    12781 atggtatgac aatgagtatg gatttacttg ccaaatgatt cgcttactag aaaaattcgc
    12841 taacttgtaa tttgatagat caatcgataa aagaagcctt tgactggatc cagtcaaagg
    12901 cttctttctt ttcatcccct acttttaaac tcgttcaatg aacatattgg cttaaaaatt
    12961 gttggactac ttgctgatat ttttcaggat ctgtcttgta tgcttccgca tgctcggctc
    13021 cttttacaac atacttttct tttggtccct tcgttgcacg atagacctta tctaacattt
    13081 caaatggtac aaatgtatct tcgtctccat gtataaagag cattgggcgc tggtttttct
    13141 tcaattgttc cactgcattt gcttcaccga aaaagtagcc agcacggact tttgtcacta
    13201 gactcgttac ttgcataagc ggaaatgctg gaagactaaa catatcgtct agctgataag
    13261 caagctcatc atgaacggaa gaataaccgc aatcttcaat gattgctttc acattatctg
    13321 gtagtttttc tccgctagtc atcataactg ttgctgctcc catgctgaca ccgtatagaa
    13381 cgatttcttg cgattttcca ttgttttcta gcactttgtt tatccactgt acatagtctt
    13441 tacgctctgg ccatccaaat ccaatgtaat ccccttcgct ttttccatgt cctcttgcat
    13501 caggaacaag gacattgtaa cccatatcat gaaacatctt tgcgtaattg gtcatcgttt
    13561 cagcgtttcc catatagcca tgagccacaa gagctgtttt ttcacttttc gtttcagcag
    13621 gaagataaat cgctgataat ttcagaccgt cttttgaagt gatggtccaa tcgcttcggt
    13681 tttcttttga actaaaccat ttatgtgcat ccgtttcttt ggatgtctgt gttgtaccag
    13741 gtgtatcttc gtctaaaaag tctttctcag aaggcacaac agcataatta taaaaataat
    13801 tccctgcaaa cactaacgca acaatcagag ctaaagcgac gcctaaaagg attttcatcc
    13861 aaagtttcat aaatcatcca tctcatttct cttttttcat ataaccttga attagtataa
    13921 tcaaagaatc tctactatgc aatgttcatt tttataaccc gcgaattgta aaattaagtt
    13981 agaaaaataa aaaggcattt atggtacact caaattgtat ttccgacgaa agaaaacaaa
    14041 ggagtgtaac cataaatgac ctacaaacat cttaccatag acgaactgac aatgatagaa
    14101 tcatattatc ttcaacataa taagccggtt gaaatcgcta accgaatggg acgtgctata
    14161 caaactattt ataatgtagt caataagttc aagcaaggca agactgctct tgattattgg
    14221 caccagtata aagaaaataa gaaaaaatgt ggtagaaaag tcattcaatt acctgctcat
    14281 gaagtagatt acattaaaga gaaagtcact cttggttgga cgcctgacgt cattatcggg
    14341 cgaaaagaaa ggtctgtttc atgcggtatg agaacacttt atcgtttatt ttctaaagga
    14401 atatttgata ttgacacact accgatgaaa ggtaaaagaa aacccaatgg ccatcaggaa
    14461 aaacggggaa aacaacagta tcagcgctca atccatgatc gacctgataa ttatcctgat
    14521 ttcaattctg agtttggtca ccttgaaggt gatacgatcg ttggcattca tcataaaagt
    14581 gccgtcatta ctttagttga aagattatct aaagtcatta tcacgattaa acccaacggc
    14641 cgtaaggcat tagatattga aactgccctt aatcaatggt tttctcgctt ccctaaaaac
    14701 ttctttaaat ctattacgtt tgactgtgga aaagaatttt ctaactggaa agccattagt
    14761 aaccaacatg atattgatat atattttgcg gaccctggaa caccttctca acgcccatta
    14821 aacgagaatt ctaacgggat tctgcgtcgt aatggactgc cgaaatcaat ggattttaga
    14881 aaagtgaatc agacatttat ttccagtgtc agcaatcaac gtaatcatat tccaagaaaa
    14941 tcattgaatt acagaacacc aatcgaaata tttttgagct atgtacaaga agcattttat
    15001 tctagcttaa tttgacaaat cataacctat aaaaaaacaa aataaaaaag cagaaataac
    15061 tggctatttc tagcggatta tttctgcaat aactaattat ctatttttta ttttcaatta
    15121 atttaaagct tgaccatggt ttcaaaaagt caaggaggaa taattcgtca tcggagattc
    15181 ttcctacaac attgacacgt ccgtcgtttt tcatatcctt caaggcgatt tgtgtttctc
    15241 ctttgtattg accgtaccct tcattgtcaa tcagtacatc cccatgatgc atatctcgcg
    15301 tattatgagg cgggaaatct ttatctttgt agtatacacg agtcatcgtt gaacgaagga
    15361 tatattctga gcgatcccct cgataactat gaaggttatc aaacaagcag attcgttcgt
    15421 tttctgtaat accttcttcc gtatctactt tcaatgttgg ataatccgcg ttaaatgctt
    15481 ctgccatttc tttcaattct tcttcacttg cgtacgcatt tccaatagaa atatcatcaa
    15541 tcaatcctgt aaggattaaa tgcttcactt gtgtcgcaat ttcaagatct cggtggtctt
    15601 ccagcgtgca caagccatct tgcgtaggcc aagggccaaa ctcagcagat tgcgaattga
    15661 cgaatgccat cgtattcaaa ttatattttc tgaatttttc tgaacaaaaa acaaagtgtt
    15721 cgtatcctaa accagagtat cgatgaggat aaaaattatg agaacctaat aaattatccg
    15781 tgtttggcga ataactcatg atgttgtcaa cgtaattcgt gcccgaactc atattgatct
    15841 cgattttgat accaaaagga ttgcgcgtca tttttgcttc ttctgctcct gtgaatccga
    15901 tatctaagcg gaccccgtag gcacccatct tatggaaaaa agataagtca tcgtaagaaa
    15961 tctccaactg ttcaaataac gctggattga tatcaaccat tacttccatg cctaggctat
    16021 tcgcgtaatc aactacttct ttaaattctg aaagaacttt ttctttatca tcattgatct
    16081 gcagcaaact ggtaaaaacc cgtttatacc catacttatg agctaaatcc aagtacgctt
    16141 tgtccttttc aaatgttgac cgttctggat aaatcgagat tcctaatttt cccatattac
    16201 catttcctcc tgcatctttt cgtttttgta tccacttaca ttatagcaaa cacaaagtaa
    16261 atggtctaca ccttttcttt ttcttttaaa ataaatgata aattccaata atttaagtag
    16321 gtattttccc tctattttgt tatcattaaa gataacaaaa tagtaaattg gaaaggaaca
    16381 gttatgaaga aaaataaagt tattttaagt attagtttag cagcagcatt gctgtttgct
    16441 gctggttgtt ctgcaaacaa cacgacttct tctagttcgt ctacagaaag ttcaaaaagt
    16501 acatctactg cggaaagcac gactgccagt agcgtcgatt tgaacgcatt ggaattacca
    16561 caattgacga aagatgtcgc cgaaaatgaa gatctggtcg aaatggtgac gaataaaggc
    16621 acaatcaaaa tcaaattatt tcccgaacac gcaccaaaag cggttgaaaa ctttatgaca
    16681 catgcaaaag acggttacta caacggactg actttccatc gcgtcatcaa agatttcatg
    16741 atccaaggtg gcgatcctaa aggcgatggc actggagggg aaagcatttg gggagaagga
    16801 tttgaaacag agatcaacaa ccacctttat aatataagag gtgcgttatc tatggctcgc
    16861 tcacaagatc ctaacagtaa cggcagccag ttctttatcg ttcaaaatac agatgatatg
    16921 catgatggtc ttttaaaaga cgactatcct caagcaatca tcgacgctta taaaaacggc
    16981 ggttatcctt cactagatgg ccattatact gtcttcggcc aagtgattga aggaatggat
    17041 gtcgtggatg ctattgcaaa tatcgaaaca gatagttcag acaaaccaaa agaagaagta
    17101 aaaatcgata aaatcaatat actgcaagaa gcaaaacaaa aataaaaaaa taacgtctga
    17161 atcctgcata gatgacaacg tatgctagga ttcaggcgtc ttctttttac ataaaaagca
    17221 agtaagcttc cttttgtttt gctatatcag gttttatagt caagcatttt ggttgacgat
    17281 gaacgtgaac tcgcactcac agactttttt atcatctaca tatgctgcag ataacgctgt
    17341 accgactgat cccttcattt tggtgatttc aaaatgacat ttcagcacat ctcctggaac
    17401 aactttttga cggaatttgg ccttattgat cccaccgata taagctcttt ttcctagaaa
    17461 ctcttctgat tttaggataa gtatcgaacc tgcttgtgcc agtgtttcta gaatcaacgc
    17521 acccggcatc actggattgt caggaaagtg accttggaaa aaatcttcat tgattgttac
    17581 attttttgtc gcaacgatct tttttcctgg ttctaaagta tctacataat caatataaca
    17641 aataggataa cgattaggaa tcaattccat tacttcagta gcagataata cgtaagacat
    17701 aattaaactc cttctttcag gcaattgcca ttttcattac tttgactatc aaagtatcat
    17761 attcctaaat atttagcaat ctttttttaa tttaagaaaa aatagtttga caatcaaaa
//
LOCUS       DAFLVO010000059        17571 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.059, whole genome shotgun sequence.
ACCESSION   DAFLVO010000059 DAFLVO010000000
VERSION     DAFLVO010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.059"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            100..1527
                     /locus_tag="L1U99_002081"
     CDS             100..1527
                     /locus_tag="L1U99_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
                     /protein_id="HBN1212615.1"
                     /translation="MMRKQSIEGRNQFAMLTIDDLVPKDHLVRKIDAAIQFDFIYPIV
                     ESTYSTYGRPSIDPVVLIKLVFIQYLFGIRSMRQTIKDVETNVAYRWFLGYSFEDPIP
                     HFSTFGKNYVRRFRETTLFEDIFSHILEQAVKAGFVTEDNLYIDSTHIKANANKHKFT
                     KEMTYGQAKAYQDELEDEINKERIAVGKRPFTWDTESELSLQKISHSDPESGYYVKGE
                     REKQFAYSAHTSCEDNGFILSTLITPGNVHDSQVAIDLVKQSKRAFPNIKRVVADAGY
                     KTPKFVHFLSHLKLYPILPYTAPHGVKGMFRKKDFVYDAYFDCYLCPNNQPLLFSTIT
                     RDGYRTYKSNPKFCVSCPLLENCTLSTKHQKIVTRHIWADLMDELEHQRHTALNREIY
                     KKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLTFAAMNLKKLATWLWKTKKPM
                     AFYFKIMQRLTKRSGLITNSFLSTI"
     gene            complement(1544..2350)
                     /locus_tag="L1U99_002082"
     CDS             complement(1544..2350)
                     /locus_tag="L1U99_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212616.1"
                     /translation="MRGDQTMSATTDMALEAVIKDNTGNVENVEDFSDIAINLSAWIS
                     AVGEENIEFEIKNMDDLKAKFPFIASKLSQVAEDKSWNELVSFSEKIYDITQEDECVS
                     WEMNNQYKKIDAFVKSRIEGTAFEFEGIDTADNWLNKESFIKSIADDLEKQWSKEDYA
                     EYLKTERDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYIVEEALS
                     QYSSDEEVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
     gene            complement(2438..3238)
                     /locus_tag="L1U99_002083"
     CDS             complement(2438..3238)
                     /locus_tag="L1U99_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212617.1"
                     /translation="MVGVSKTALDSLAKLFSSRFDGAEFVEYLSQNESGKTLIETMKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIGGDTYPDAKSLATSDFKT
                     FYGYLIGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYANDREKVKLLEGKLSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGEWNFQDDLVAFSNDG
                     YLRSYSESEYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKEEL"
     gene            complement(3577..4686)
                     /locus_tag="L1U99_002084"
     CDS             complement(3577..4686)
                     /locus_tag="L1U99_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBN1212618.1"
                     /translation="MKNKILLFLTLICTLVLTIYPANQLYHQFKTKENVAEIQEKIEK
                     KQTPSKEEVAKKVEQIKSNSGNQGLDNTQKTDKGVDNTQETDGGSFDIREAEGKVNPY
                     TGDVFSKNQTKDFEPSTYSGAVGYVYIPKINVLELLFLGASQEHLYRGVAQMSATSLP
                     LSGKGHQTVIAGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRTDVIRNYGQ
                     NSTLTDIPDLDMLTLYTCHPYPQNYDRLLVRSLRDEKAKYITPQVTVGNTAYADAIDS
                     ESVSDKTETVTSSNDLFEDVDRANKELDGNNDLNIPEQGSVEMQDRTFAEKASSIFTG
                     ITNKHQKMLLVIWTVIGALASLKVLILLIKEFRKA"
     gene            complement(4676..5539)
                     /locus_tag="L1U99_002085"
     CDS             complement(4676..5539)
                     /locus_tag="L1U99_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBN1212619.1"
                     /translation="MSMKKKNIKLIILKIGMLLCLGVGLYPVITQAYTYYQTQQTLNS
                     YKEKYDEASEKENEEVFKRYSEVNRKRKDTEQTSVTIPEDNNNIPSNGNLQKDKLGEL
                     VGEILIPKINVDLPIYDGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKY
                     FTDLELLKLGDKFFIDISGKKLAYQVDRIKTILPTEFEDLLPVAGKDYVTLMTCTPVG
                     DNSHRLLVRGVSIPYQKSIVEKEKKKEDLKVKAQMNWYPIVVVGVLLIIAVIVIIKKI
                     VAKRRGMKNEE"
     gene            complement(5608..7443)
                     /locus_tag="L1U99_002086"
     CDS             complement(5608..7443)
                     /locus_tag="L1U99_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBN1212620.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSSLGLGGQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGNPVSDIDNKGKEIALPNGVKPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPIQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANKTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     NYEKYVVKDVLGAELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTESGMDKLQKQFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNKVTYLKQDPTTKSVTWIADKSKATEFVSGSDGKFQ
                     IEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDVPFVVSNDDASSE
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            complement(7492..9882)
                     /locus_tag="L1U99_002087"
     CDS             complement(7492..9882)
                     /locus_tag="L1U99_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HBN1212621.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMMLSTLIMPFSAIRAEADVTKPT
                     SAKFIETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGAGSDEFYRMFKGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     EFSYTATNTIKKGKVKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGVFKQEGITVKDDGQTFEYTATNTLKKGLVKVHKVDQDGKPL
                     ANAEFTLTDEKGATQVEKTDENGLASFNIVANKTYSLEETGVPVGYTGAFKQEGITVK
                     DDGQTFEYTATNNLKKGVVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDSNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDGQTFEYTVINHLVPETVRTGGIGTSAFLLVFLIAGLSMVLLYYREQHKAK"
     gene            complement(10150..11397)
                     /locus_tag="L1U99_002088"
     CDS             complement(10150..11397)
                     /locus_tag="L1U99_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBN1212622.1"
                     /translation="MNMKRNSLGMVLLASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNISK
                     DTLTVKEADGEVVSQTVQKDKPDPIENTEQENKKSETTKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTEADTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDSSTSPSKPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKPMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
     gene            11789..12205
                     /locus_tag="L1U99_002089"
     CDS             11789..12205
                     /locus_tag="L1U99_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212623.1"
                     /translation="MNKKRKLSVLITLVSILTILSVILSLKIFNQINTSSNAKDGIVV
                     ENTSNSKETGTTTKKYKSAEITTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKNDELYSFVK"
     gene            complement(12222..12959)
                     /locus_tag="L1U99_002090"
     CDS             complement(12222..12959)
                     /locus_tag="L1U99_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212624.1"
                     /translation="MADHKLEKLLEETWNPKEFSEFFMENFETDLAVIVKDALREQGY
                     PETANYININFTLYTENKGTWDFWATLANKELSDKSDTGIRNFFESNRDDYMYANNQN
                     KLNFRVEFDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISELGGQYEPLVEAVRE
                     ELRLNKFPDVQNIDVSQIEINVKITNKLDYGSWADIALEKYIYSTLKEFIENRMDIMY
                     LQHPQYLNFGVEIATPLEEWKMEQGLD"
     gene            complement(13381..13944)
                     /locus_tag="L1U99_002091"
     CDS             complement(13381..13944)
                     /locus_tag="L1U99_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212625.1"
                     /translation="MQNHEITTAKKAIGILSIIVILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLEDLDSYVRAE"
     gene            complement(13931..14458)
                     /locus_tag="L1U99_002092"
     CDS             complement(13931..14458)
                     /locus_tag="L1U99_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212626.1"
                     /translation="MNSKVKDTIIISLLSGMLLALLVGILFFNKQNQDIEAEKHSVHI
                     EDKLTFFKEVKPNEVDGLRKDLENDIQEMLNGSVQNKFADQSGEEFLRKLFIVTGKPP
                     ITDKSSEKEKIEYYKPFTFKLTNFGIKTSSSGLYEALTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            complement(14481..15818)
                     /locus_tag="L1U99_002093"
     CDS             complement(14481..15818)
                     /locus_tag="L1U99_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HBN1212627.1"
                     /translation="MLMVQFTGIAMSVITINPQVIHADGIATYDAQFNCTTEGSGSGT
                     DSDGNDTGSGAVTGDVAKNIEDIYKYMNGEYGLSGASIAGILGNWKQESGIDPRAVEG
                     YYGDGQREVDFIKQFTDGLMGIGYGQWTAGRHTALVDWSKKNNGGSWWTTEAQLDFMF
                     KGDGGFVGILKDYALNASDDVVENAVTFHKNWEISADSESAVIAVRGENAKEIWKYMK
                     SKGMDGAKDESKINKISGGSSTGDGSNNSSSSASGTVEDACATTDDANSGSGSIGKEG
                     KINGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFNGIYQGQCTELTWAYMS
                     QLYDGNQPTTGNGGYVWESYKSAGAKITNKPIVGYGFSASDGWLWAVGDAGHTGVVIA
                     VFEDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFSGVGKAKFEIEK"
     gene            15938..16417
                     /locus_tag="L1U99_002094"
     CDS             15938..16417
                     /locus_tag="L1U99_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212628.1"
                     /translation="MTDKTSDLPKLAPKTSRVKSKKDGKTKNAVKKKSVKETSSLLLD
                     IPMSSFDDNTDETSVKIATHVGMNNQNDSFYNLLNSLRELEDKKNQVIASKAPDLTTD
                     LDAEIIQIKQDERSVKSLLKTYFDGFDKELAPYSQAILTKPIQAPHISISLQKKSDD"
     gene            complement(16532..16764)
                     /locus_tag="L1U99_002095"
                     /pseudo
     CDS             complement(16532..16764)
                     /locus_tag="L1U99_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321015.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(16767..17084)
                     /locus_tag="L1U99_002096"
     CDS             complement(16767..17084)
                     /locus_tag="L1U99_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212629.1"
                     /translation="MKREEYKQRLNELLEEDETLTHGSPDEILYMIDNMVIFGGYELG
                     NRSVDHNILEFDDVSWEEILDWGILAVPETKTYISDTMVPFFEELDYKRLPKNENHIL
                     GGN"
     gene            complement(17195..17377)
                     /locus_tag="L1U99_002097"
     CDS             complement(17195..17377)
                     /locus_tag="L1U99_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212630.1"
                     /translation="MAVNKILQVLIIDEFGGGEWFDVQSIDFEEEVVVIENIYGEVYS
                     YSLEGENIEDLRLIGE"
     gene            complement(17414..>17571)
                     /locus_tag="L1U99_002098"
     CDS             complement(17414..>17571)
                     /locus_tag="L1U99_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212631.1"
                     /translation="RVSIQLPTGQISLGEKDYLIKVGKELIIKVPEHLFKENFEIRET
                     LVWKEEK"
BASE COUNT         5094 a         3523 c         2529 g         6425 t
ORIGIN      
        1 cagctctatt cagactgtag acaaactcct aaatttggag tgttgtttgc agttttttgt
       61 tttatactaa ttgtataaac tattctggga gtgattctaa tgatgagaaa acaatcgatt
      121 gaaggtagaa atcaatttgc tatgttaaca attgatgatc ttgtacctaa agatcactta
      181 gttcgaaaaa ttgatgctgc gattcagttt gatttcattt atcccattgt agaatctacg
      241 tattcaacct atggtcgtcc cagtattgat ccagtggtct taattaaatt agtatttatc
      301 caatatttat ttggtatccg ttcgatgaga cagacaatta aagacgttga aacaaatgtt
      361 gcttaccgtt ggtttttagg ttattcattc gaggatccta tcccacactt ctctactttt
      421 ggtaaaaact atgttcgaag atttagagaa acaactttat ttgaagatat tttctctcat
      481 attctagaac aagctgtaaa agctggcttc gttacggaag acaaccttta tattgattct
      541 actcatatca aagcaaatgc caataaacat aagttcacga aagagatgac ctacggtcaa
      601 gcaaaagctt atcaagatga attagaagat gaaataaata aagaacgtat tgctgtagga
      661 aaacgtcctt ttacatggga cacagaaagt gagttgagtc ttcaaaaaat aagtcattca
      721 gatccagaaa gtggttacta tgttaaaggt gaacgagaaa aacaatttgc ttattctgca
      781 catacttcct gtgaagataa cggttttatc ttatctacat taatcacacc aggaaatgtg
      841 catgacagcc aagtcgcaat cgatctggtt aaacagtcga aaagagcttt tccaaatata
      901 aagcgtgtgg ttgctgatgc aggatataag acgcctaaat ttgttcattt tctgtcacac
      961 ttgaaactct acccgattct tccatatact gcacctcatg gagtgaaagg aatgtttcgt
     1021 aaaaaagact ttgtttatga tgcctatttt gactgctatt tatgtcccaa taatcaaccg
     1081 ttgttatttt caactatcac tcgtgatggt tatcgaacct ataaatcaaa tccaaaattc
     1141 tgtgtgagtt gtccattact tgaaaattgt actttgagta caaaacatca aaaaatagtg
     1201 actcgacata tttgggctga tcttatggat gaacttgaac accaacgcca tacggcgttg
     1261 aatagagaaa tttacaaaaa gagaaaacaa accattgaac gaatatttgc agatgcaaaa
     1321 gaaaagcatg gtatgcgttg gacgaaatat cgaggtcttg aaaaagtcgc cacgcacacg
     1381 atgcttacgt ttgctgccat gaatttaaaa aaactagcca catggctatg gaaaacaaaa
     1441 aagcctatgg ctttttattt caaaattatg caaagactaa caaaaaggag tggcttaatt
     1501 accaactcct ttttgtctac aatctgaata gagcttttca gctctattca atatcatttt
     1561 gatcaattaa taatcgtaca ctccaattaa ccgagttttg atcactcaaa tatttataat
     1621 ctttgtcatc aaaaaccagt tgccaaactc tggtacgaac agtttcttcg tccacttcct
     1681 catctgaaga gtattgcgat aatgcttctt caactatata ctttacaact tcctcaaaat
     1741 cagtaggaac tttatcaata accacttcat agtcttcttg ttttacgata ttgggatcaa
     1801 tatgttcatc caaacatacc tcagtgagtt tttctttcac ttctgtatct ctttctgttt
     1861 ttaggtactc tgcatagtct tccttagacc attgtttttc aagatcatcc gctatacttt
     1921 taataaagga ttctttattt aaccaattat ctgcggtatc tataccttca aactcaaaag
     1981 ctgttccttc tatacgtgat ttgacgaaag cgtcaatttt cttgtattga ttattcattt
     2041 cccatgaaac acactcatct tcttgcgtaa tatcataaat tttttcggaa aaactaacta
     2101 attcattcca cgatttatcc tcggcaactt gacttagttt cgatgcaata aaaggaaatt
     2161 ttgcttttaa gtcatccata ttcttgatct caaattcgat attttcttct cctacagctg
     2221 aaatccatgc tgaaagattg attgcaatat cgctaaagtc ttctacattt tcgacatttc
     2281 ctgtattatc ttttattact gcttctaaag ccatatcggt tgttgcactc atggtttgat
     2341 ctcctctcat aatagagcaa aaagccggtt taaccgactt tttgcatggt acgttttgtt
     2401 tggtagtttt ctgcttgtgt ttatgttgaa ataatcccta tagctcttct tttaatagtt
     2461 cttcaacttt atctcttaac tctccctgac cactctctaa tagatttaaa tagctcatca
     2521 gaatatccgt ttcatacgtt tttaattcag ctctatactc actttctgaa tatgatcgta
     2581 aatacccatc attgctaaat gcaactagat catcttgaaa gttccattct cctaaatttg
     2641 ttttacttac tgcttcccat ggactattac taaacatttc attaaagaaa tcttcgtcat
     2701 tttgatatac cttcaattca ggaaaatagt tgctgtcttc attgatttct tgcaccattt
     2761 ttccaagttc ttcttcagat aatttacctt ccaataattt tactttttct ctgtcatttg
     2821 cataagccat ttgaacctct cctttttctt tttcaatttc ttcaggtgtt tgttttggcg
     2881 taactttcaa atctattcca ttgcctatta gacctattag ataaccatag aacgttttaa
     2941 agtcacttgt agcaagagat ttggcatcag ggtatgtatc ccctccaatt ttatctaaaa
     3001 caaaatcagc aatcgttacc caaggagaat atatcgtaca tactacatcc catgtagcat
     3061 cttcaatatt cgtccatgtc ggaaagtcat tttcattcaa atagtctttt ttcattgttt
     3121 cgatcagagt ttttccactt tcgttttggc ttagatattc aacaaattct gcaccatcaa
     3181 acctgctact aaatagttta gctaatgagt ctaaagctgt ttttgatact cccaccatta
     3241 ctacacctcc tattaatatt ttacgatgac ttgtttttca ttcacaaata agattttcta
     3301 catcttatct attgctttat agcttttcca tacattattt ctaaatacaa ccaataaccc
     3361 tattaaatta agcttttgag tttatctttt ctaataatat tctgataaat attctgataa
     3421 aaaaatttat tgtatttttt tcttgacttt ttctttagaa ttaagatcag ttttgatttt
     3481 atttaaaagt gaatctagct ctattcaaaa taaaaaagag atcaataata gtatcaatcc
     3541 ctttttactg tactctatca atttttataa tcttcattat gcttttcgaa actctttgat
     3601 taaaagaata agaaccttta gacttgctaa tgctcctatt acagtccaaa tgactaaaag
     3661 cattttctga tgtttattgg taattcctgt aaatattgaa cttgcctttt cagcaaacgt
     3721 tctgtcttgc atctctacgc taccttgttc cggaatatta agatcattat ttccatctaa
     3781 ttccttgttg gcacgatcaa catcttcaaa taaatcatta gaagatgtaa cagtttctgt
     3841 cttatctgaa acggactcgc tatcaatggc atcagcgtat gcggtattgc caactgttac
     3901 ttgtggcgtg atgtattttg ctttttcatc tcttagactt ctaactaata aacgatcgta
     3961 gttctgagga tatggatgac aagtataaag tgttaacata tctaaatcag gaatatcagt
     4021 cagtgttgaa ttctgaccgt aatttctaat aacgtctgtt cggaaaaccg tataaactgc
     4081 tttttcacca agataatcta tataaatgtg gtctccggct actaattgat caacataaag
     4141 aaattgtggt gacgtataac cgccacgatg acctgctatt actgtttgat gacctttacc
     4201 tgataaaggt agactagtag cactcatttg tgccacacct ctatataaat gctcctgtga
     4261 agcgcctaga aacaaaagct ctagcacatt tatttttgga atatagacat aaccaaccgc
     4321 tcctgaatag gtagatggtt caaaatcttt cgtttgattt tttgaaaaaa catctcctgt
     4381 gtatggattg acctttcctt cagcttcacg aatatcaaat gatccaccgt ctgtttcctg
     4441 agtattgtct actcctttat ctgttttctg agtattgtct aatccttggt taccgctgtt
     4501 cgattttatt tgttcgactt tttttgccac ttcctctttt gaaggagttt gttttttctc
     4561 aattttctct tggatttccg ccacattctc ttttgttttg aattgatgat agagctgatt
     4621 tgcaggataa attgttaaaa ccaaagtgca aataagagtc aaaaaaagta gtattttatt
     4681 cttcattttt cattcctcgt ctctttgcta ctattttttt aataatgact atcacagcta
     4741 ttattaataa aacccctaca actacgatag gataccagtt catctgcgcc tttaccttta
     4801 aatcttcttt cttcttttct ttctcaacaa tacttttttg gtaaggtatg ctaacccctc
     4861 taacgagtaa cctatgagaa ttatctccaa caggtgtaca tgtcataagt gttacataat
     4921 cttttcctgc cacaggaagc aaatcctcaa attcggttgg tagaattgtt tttatccgat
     4981 ctacttgata agcaagtttt ttccctgaaa tatcaataaa aaatttatca ccaagtttga
     5041 gcaactctaa atctgtaaaa tattttttat taggaatgcc tgaatgagct gatataacag
     5101 aatggtttcc aatcccacca gttggataat cagttccggt taatattcct gctcctgctg
     5161 atagttggaa atcgtttaca ccatcataaa ttggcaaatc cacattaatc tttggtataa
     5221 gaatttcacc cactaattca cctaatttat ccttctgaag atttccattt gacggaatat
     5281 tgttattatc ttcaggaatc gtgactgagg tttgttctgt gtcttttcgt ttcctattaa
     5341 cttctgaata tctcttgaag acttcttcat tctccttttc agaagcttca tcatattttt
     5401 ccttatagga gtttagtgtt tgttgagttt ggtagtaggt ataagcctga gtaattacag
     5461 gatatagacc tactcctaaa catagcaaca tcccaatttt taagatgatc aacttgatat
     5521 tcttcttttt catgctcata cctacttttc acacactttt taaaaagaaa ccctagagcc
     5581 aaaaacactc tagggaattt tatttcatta agctttgtgt tgttctcgtt tgtagacaac
     5641 atatagccct gttcctgcca cacctgcaac cactagaaat actactgttc caattccacc
     5701 tgtacgaact gtttcaggtg ttttaaggtt cttgatgtct gttacttcgc tagaagcatc
     5761 atcattcgat accacaaatg gaacatcatt tctagttggt gtatatcctg aaggagcaac
     5821 aacttcttca agagcataat cattgatttt tttatctgtg attgttggat taccttgttt
     5881 atcaaaatct acatcatagg tatattgcaa gccttcaatt tggaacttac catctgatcc
     5941 ggaaacgaat tcagtagctt tagatttatc tgcaatccaa gtaacagatt tcgttgttgg
     6001 atcttgtttt aggtaagtaa ctttattcgg atcaattttg ttcttcacta caaattttgc
     6061 tccactcaat gctttgcttg tatctccatc tgttttaatg aattggtgat caccaatgat
     6121 tgtataagcg tgatcaactg gtgtttcgtc ttcgggttca tatccattgt tgtagatcgt
     6181 tgaaacatca ttcttaagtg gtgtatccat tttagcttta ctattagtat gagcgttcat
     6241 caaaattgta aagaagcgat cccctgcatc aaattgtttc tgaagcttat ccatacctga
     6301 ttcagtaaag acatagtttg tcgtttgtcc gtcacgttcg atactgtaat cagtatctaa
     6361 agtcattcct tcgatcactt ctgatgaatc ataagttaac tctgcaccta gaacatcttt
     6421 gacaacatat ttttcgtaat taccaatatt accaggaatt gatggtttca atgtatattg
     6481 aacatcttcg ccagtatcaa cggtttcttt atcaattacc ttagtaatta caggtcgttt
     6541 gtagttggta acatcaagaa ctactttagc agtctcccca cgtttaacgc taaatttgaa
     6601 ttttttacca tctagtaaat aggttgtttt attagcatct gttcccaaat cggtttctag
     6661 gaaataatag tcacctaatt ccaaaccatc tacagttaat ttacctgtgc tgtctgtttt
     6721 ataagttcca acaacctgat cagatccatc atcttttcgc aattcaaaaa cagttccggc
     6781 aagagccttt ccatcttcgt cttttttatc aagctctgct gagtttaatt ggaaatagtt
     6841 tttaggatag acatgtacat cataattaaa gtattgatca tctgatccgt ttagttcagg
     6901 tacgttaaca atcataggat acgcttcttc aactacacct ttgactgttc ctgtttcaac
     6961 aatcaaatac aagttatctg ttaaatcgtc tgtatttact tgtataggta tgtctatatt
     7021 cccttgtgaa tcagtcttca ttctacttac ttcactgtat tttttgttta gtaataatcg
     7081 tgctttagca tcatcaatat gttgaccttt tgtagtatca ctatccgtcc atcccaagga
     7141 tttagcttca tctttagtaa gtttcacata agagaactca acgccttcaa gaggttttac
     7201 accatttggt aaagctattt ctttcccttt gttatcaata tctgagacag ggttcccatc
     7261 cccattagta tttgttactt tatggatatg aatcgttcca gttccttgat aattatagtt
     7321 ttgttgtgca tatgctactt gcccccctag tccaaggcta gaagagattg agcttgcgcc
     7381 caatcccact cctagcaaag taccaaatag cattaaattt gaaaaaattt tttttgattt
     7441 catacgtcag ccttcttttt tcatatttac ttcttttcca ttaacacttt tttattttgc
     7501 tttgtgctgt tctcgataat acagtagcac catactcaat cctgcaatta gaaatacaag
     7561 aaggaaggct gatgtaccga ttccgcctgt tcttactgtt tcaggtacaa ggtgattaat
     7621 tactgtatat tcaaaggttt gtccatcgtc agcaacggtg atgccttctt tagaccattt
     7681 ccctgtataa ccattagggt tttgtgtttc ttcgattttg tacgttttgt tggcaacaat
     7741 attaaatgtt gccaagccat tgctgtccgt tttttgtaca acttttacac ctttgtcgtc
     7801 tgtcaaagtg aattctgcgt ttgctaatgc tttcccttga tcatccactt tatgaacttt
     7861 gatcacacct tttttcaaag tgtttttagc agtatattca aagacttgtc catcatcttt
     7921 gacggtaatt ccttcttgtt tgaatgcgcc tgtgtaacct gttggtactt ttgtttcttc
     7981 taagttataa gttttgttcg caataatgtt gaacgtagcc agaccagttg catccgtctt
     8041 tttaacttct tttacacctt tttcatccgt taaggtgaat tctgcatctg ctaaaggttt
     8101 tccatcttga tcgactttat gaacttttac tacacctttt ttcaaattat ttgtagctgt
     8161 atattcaaaa gtttgcccat cgtctttaac ggtgataccc tcttgcttaa atgcacctgt
     8221 gtaacctact ggtactccgg tttcttctag gctatacgtc ttgtttgcta caatattgaa
     8281 gcttgcaagt ccattttcat ctgttttttc tacttgtgtt gcaccttttt catcggttaa
     8341 agtgaactct gcatttgcca aaggttttcc atcttgatcg actttatgaa cttttactaa
     8401 accttttttc aaagtgtttg tagctgtata ttcaaaagtt tgtccatcat ctttaacggt
     8461 aattccttct tgcttgaata cgcctgtata accagttggt actccggtct cttcaaggct
     8521 gtaggtcttg tttgctacaa tatcgaagct tgcaagtccg ttttcatctg ttttttctgc
     8581 ttgtgtttgg gatgaatcat ccgtcaaggt aaattcagca ttagctaatg gttttccatc
     8641 ttggtcaacc tttttaactt ttactttacc ttttttaatt gtgttcgtag cagtgtaact
     8701 aaattcttgt ccatcggtat taacagtaat accatccttt ttaaatgaac cttgataacc
     8761 ttcaggaact tttgtttctt ctaagctgta tgttaagcct tgttgcaaat caaacgtagc
     8821 taacccatca tctccggttg tcttaacaga tttagcattg ttattgtcag ttagagtaaa
     8881 ctccgctcct tttaaagcat ttccatcttg atcaactttc ttaactgtta cctgaccaac
     8941 agctcttgtc catttagcac tcaaagattt agagtccttt gtttctgaag tagtgatcat
     9001 aactacggca tcttgataca cacctcgtcc atcaaaagta aaaggattgg ttgtgctaac
     9061 attagcagta cctttaaatg acaaagtacc acttggtgta gtcacaggta ctttaatagt
     9121 aaaacttgaa tttaatttca cagtgttgtt agtaatttct ttaccatctg catcataaat
     9181 cttcatacca gctggttttg ctgatgtaaa agtgagcttc gcattaccag tcttatttga
     9241 tgctgtttta tatgtgaaag tgtgatattt tccttcgtca gctgtcttag aagctgtgat
     9301 agaaaactca gtgttgggcg tatcttttcc attcttagca tagtcataaa ttttttcaaa
     9361 tgcttttttt acacgagctg tttctgcggc ggtatggttt ggatgtgacc atacaatctg
     9421 tgaaacttta aagtttccgg ctaaaaccca tgaaactaat tgtgttgcat accatgcttc
     9481 tgtatcattt cctgcaccca gttcctttgc tgtttttgat ggaaaaccac ctttaaacat
     9541 acgatagaac tcatcactgc cagctccctt gtacttcaag cttccggctc cacttcctgt
     9601 tggggatggc aattctgaat ccatacaata tccaatattt ccatgagaat ctttaaattg
     9661 acttgaaatc atccattcat ttggatgatt cggcatatta accctaatat aaccgtctgt
     9721 ttttacgcca gtttctataa attttgcact tgtcggtttt gtgacatctg cttcagctct
     9781 tattgctgaa aaaggcatta taagcgtaga taacatcatt actaaagtcg caaaacaata
     9841 aattattttt gattttaaaa ttatcgtttt ttcatgcttc atctctcgtt actccttctt
     9901 tataccagtt aggcgaagaa aatgagccac gatatgtcgg tgtggtaatg accttcgcgc
     9961 ccattcctaa gttaaaatca ccacacctat taatcatttt tttcgttgaa agcaagctgt
    10021 ttcaacgctc tagtattcat agcatcaccc cttttagttc tacccaccat gagcaacaag
    10081 ttttctaagt agttaagcaa ggacaaataa agactatata actacttagt atataaacga
    10141 tatcttttat taacgtaccg aaaccgctaa ttgagatacg ttatatgctg tttcaaatga
    10201 tcctgcatta atccaacttg ccccaaacac aggatcgaca acatggtaaa aaccgtcttt
    10261 aaatccatca acggctacta catgtcgatt ccaaatagca tcgccccaaa acattggttt
    10321 atgttgagca ggttcaaagg cataagttac ccacgctact acaggatttc catttacaat
    10381 ctcatctttt aatccttgta ccgatgaacc agaaatatct acaacatttc cgccattagc
    10441 aacaccccat gaaactacag gagccggatt cataccttga taagttccat ccacattgtg
    10501 tctccattca ccagaaaaac cattatttgg attattgtca ggagatagtg gcattgattt
    10561 aacaaaagtc attaaatctt gatttgttgc aacaccttta taatgtaacg cttctagcaa
    10621 agatgttcct tcgcaaagca ttgtgttacc ttgactaata aatggaacgc ctagcacaac
    10681 attagttggt tgttcgggtt tacttggtga agtagaactg tcagtttcat cactcgaacc
    10741 tgtttgtgat tgatcactag aagatgtact ggttgattca tttgcatcat ttgatgttga
    10801 ttgtgagtta tttgttgatg ttccagtatc agcttccgta gtgctacttt cacttgttcc
    10861 ctgtgatgct tctttctcac ttgtagaatt atttgtatta gatgaacttg ctccatcaac
    10921 acttgaagca cttgtttctg tcttatcaga agtgtttgct gttggttccg attcttttgt
    10981 agtctcggat tttttgttct cttgctccgt attttcaata ggatcaggtt tatctttttg
    11041 aacagtttga ctaactactt cgccatctgc ttccttaact gttaatgtat ctttactgat
    11101 gttgaaagtt cgtccaatcg ggatagtccg ttgttctcct tttgccaaat caacattgtt
    11161 caattcggca aactcagcaa cagtagtctt gtaacctaag cttttaagct tctctacagt
    11221 tgaccaaata gtatctcctt ttttgaacgc ataacttgat tgtcctgttg taatttggat
    11281 ttgatccggt gtgtttgcag tccattcatc agcatgtgag gttactggta ctgataaccc
    11341 cgcaagtaca gctgatgcca ataaaaccat accaagcgaa tttctcttca tattcattcc
    11401 ttctttttgt ttttattttc tgtttgtgat cgcaatgctt ctattccttc ttccgttata
    11461 atataggttt tgtcacccac tttcttgaac gaacctttag gcaaacgatt tggataatag
    11521 ttgattatgt ttgtaacata atttctacct ttacccaaaa tcaaacttgc ttcccttgcg
    11581 gtatacaagt tgtatttgtc taggttcaat ttctttttgt ttgcgattta gacctacccc
    11641 tttcgcaaaa tttattgtat aataatagta ccattgcact gtcataattg caatattttt
    11701 tggggtttat cttcatttaa tagcctaaaa aggcttgtta gataaggaat atctaactaa
    11761 tcaaaacaaa aaaggatgtt aagaaaaaat gaacaaaaaa aggaaattat cagtattaat
    11821 tacacttgtt tctatattga ctattcttag cgttatcttg tcgctgaaaa tattcaatca
    11881 aataaacaca agctcaaatg ccaaagatgg aatagtcgta gaaaatacct ctaattctaa
    11941 agaaactggt actactacaa aaaaatacaa atctgctgag atcactacga aaaattattt
    12001 aataaagact gtttattttg atgaacgaaa aacagcaatt ctcaaagatg aggaaggatc
    12061 agaattaaag ctacctataa cggtatccga taagttcaat ggaacgttct ccttacaaac
    12121 cgctgaagga tcacctgaca atctcaaagt tgggcaaaca atcattcttg gtaaaaacga
    12181 cgaactgtat tcatttgtaa aataaaaaaa tggagcaaag gctagtcaag cccttgctcc
    12241 attttccatt cttcaagagg tgtagctatt tcaacaccaa agtttaaata ctgtggatgc
    12301 tgtagataca tgatatccat tctattttcg ataaactctt ttaacgttga gtagatgtat
    12361 ttttctaatg ctatatctgc ccaactacca taatcaagtt tattcgtgat cttgacgttt
    12421 atttcaattt gagaaacatc aatattttga acatcaggaa acttattcag tcttagctct
    12481 tctctaaccg cttctactag cggttcatat tgtccgccta gttcgctaat tgttgaaact
    12541 atttcatctg aattccaacg atcttccaat acctttgcta cattttcttt aggcggttgt
    12601 ctttctataa attcttcagg tgtttcatca aactctactc taaagttcaa tttattttga
    12661 ttgttagcat acatataatc atctctgttt gattcaaaaa agttacgaat tcctgtgtct
    12721 gatttatcac ttaactcctt atttgctaaa gtagcccaaa aatcccaagt tcctttattt
    12781 tcagtataca aagtaaaatt aatgtttata tagtttgcag tttcaggata cccttgctct
    12841 ctaagagcat ctttaacaat cactgctaag tcagtttcaa aattctccat aaaaaattca
    12901 ctaaattctt ttggattcca cgtttcttct aataactttt ctaatttatg atctgccatt
    12961 attattctcc cccactttac tttcaatctt atatctaaaa ctgcttaaaa ttaagagcta
    13021 taccttatca taaaaggtat tttatgcttt atttaagtct acaattctat attacaatta
    13081 tcatctagac cattttctta tgtcaaataa accatatata ttgtctttaa tagttttatt
    13141 tgacttttta agaaagtatt tacttttgac tttttttacg ttttacaaca tatacgtatt
    13201 gtaatgttca gctcaattta ttataatcta aatgaattga ttaataaaaa ttctgaggtt
    13261 cgggtttttt atcaattctt ttctgtttgt gtttgtgatg aaacaatcct ttttcggtag
    13321 gttttgttat catcgtcagc acaaagagct aacgttggta ccgttagctc tttttttatt
    13381 ttactctgct cttacatagc tatctaaatc ctccaaataa aacaattgat tttctcctat
    13441 gcttgttact ccacgccaaa ttgttgttgt tgctgttgtt ggagtatttc ttgtctgtgt
    13501 aatcaattca accattttac ctttttgatt tgttgtatag taatcagcag tatagctaga
    13561 tattggacta ttaccagtgc ctaccatcgt gccagaaata tcaacaggac tagactttac
    13621 tatctgagga aattcttttt gtatttcctt catattcttc gtatattttt cccatgaatt
    13681 ccagttgtaa aataaattaa agaatttcct actttgttcc ttaatttcag catttcccaa
    13741 ttctttgtat tgagcttcct gcatagcttt cactttctgg ttattcttga ctacttcgat
    13801 ttgtttactt ttaaggtctt ccaattcttt gacattatta tcataagcat ttttcttttg
    13861 aaatagtacc acacaacaaa ggatcacaat tatggaaagt attccgatcg cctttttagc
    13921 agtagtgatt tcatgatttt gcataaaaag cacccccagt cactttctta tcattattta
    13981 gtgtgatggt taatgtggta tcatacactt tttttccatt gtattgaact tcaaaatcgg
    14041 tcaatgcttc atacaaccca ctactagatg tcttaattcc aaagtttgtt agcttaaaag
    14101 taaaaggctt atagtactcg attttttctt tctcactact cttatcagta attggtggtt
    14161 tacctgttac aataaatagt tttctcaaaa attcttcacc tgattgatct gcaaacttat
    14221 tttgaactga tccattcaac atttcttgaa tatcattttc taaatctttc cgtaatccat
    14281 ccacctcatt tggtttaacc tctttaaaga atgtcagctt atcttcaata tgcacactgt
    14341 gtttttcagc ttctatgtcc tgattctgct tattgaagaa taggattcca acaagcagtg
    14401 ctaataacat accagaaagc aaagaaatga taattgtatc tttcacttta ctattcatct
    14461 atatcgtcct tcattccaat ttatttttcg atttcaaatt tagcttttcc tacaccgcta
    14521 aagaaatgca cattatctga tccgtccact ccatcaatca acgttaccga aactcccctt
    14581 gttggagctt gggttggtgg aacattaaag ttagcacata gaaatgatcc atcttcaaac
    14641 accgctataa ctacaccagt atgccctgca tctccaacag cccataacca tccatccgaa
    14701 gcactaaacc cataacctac gattggtttg ttcgttattt ttgctcctgc cgatttgtag
    14761 ctttcccata cataaccacc atttccagta gtcggttgat tcccatcgta taattggctc
    14821 atataagccc acgtcaactc tgtacactga ccttgatata ttccgttaaa aggtgaagtt
    14881 gaccaatctg gttctttgaa ttttggtagc gtgatcgctt tcccatattt tttcaaagct
    14941 tcttcataag tcatattcgc tattacttga ccttttttac cgttaatttt tccttctttc
    15001 ccaattgatc cagaaccaga attagcgtca tccgtagttg cacaggcatc ttctactgtt
    15061 cctgatgctg aacttgatga attattcgat ccatctccgg tacttgaacc tccggatatt
    15121 ttattgatct tactttcatc ttttgcaccg tccataccct tgcttttcat gtacttccag
    15181 atttcttttg cattttcacc acgtacagct attacagctg attcggaatc agctgaaatt
    15241 tcccagtttt tatgaaaagt tactgcattt tctacgacat catcagaagc atttaaagca
    15301 taatctttta atattcctac gaatccccca tcacctttga acataaagtc caattgggct
    15361 tctgtagtcc accaagaacc gccattattt ttcttagacc aatcaactaa tgctgtatgt
    15421 cgcccagctg tccattgacc atagccaata cccatcagac catcagtaaa ttgtttgatg
    15481 aagtcaactt ctctctgtcc atctccgtaa tacccttcta ctgctcgagg atcaatacct
    15541 gattcttgtt tccagttacc taaaatacct gcaatactag cacctgataa gccatattct
    15601 ccattcatgt atttgtaaat atcttcaata tttttggcta catcacctgt tacagcgcca
    15661 cttccagtat cgtttccatc gctatctgtc cctgacccac taccttcagt agtacagtta
    15721 aattgtgcat cataagtagc tatcccatca gcatgtatca cttgcggatt tattgtgatt
    15781 acactcattg caatccctgt aaattgcacc attaacataa gcaatgtggc aatctttctc
    15841 ttagattttt tcaataacta cgcccccaaa aagtgtactt ttttatgtta ttatgataat
    15901 ataataacat aaattaatag aaaggaaaag ctaataaatg actgataaaa caagtgattt
    15961 acctaaacta gctccaaaaa catctcgagt aaagagcaaa aaagatggaa aaacaaaaaa
    16021 tgctgtaaag aaaaagtcag taaaagaaac atcctcgtta ctacttgata ttccaatgag
    16081 ttcttttgat gacaatacgg acgaaacttc tgttaaaatt gcaactcacg ttggaatgaa
    16141 caatcaaaat gattcttttt acaacttgtt aaacagccta agagagttgg aagataaaaa
    16201 aaatcaggta atcgcatcaa aagctcctga tctcacaacc gatttggatg ctgaaattat
    16261 ccaaatcaaa caagatgagc gatcagttaa atcgctactg aaaacctact ttgatggttt
    16321 tgataaagaa ctagctcctt atagccaagc aatcctaact aaaccaatac aagctccaca
    16381 tatttcaatt tccctacaaa aaaagagtga tgattaaaca atcattactc ttttttagat
    16441 ttctggtaag cgctgatcgc aaaaaccatc aacaatattg attcaaaaaa tatgttcatt
    16501 cgtgtctctt ttttccatta tagatttccc actattccat taaatcgaaa gtcacaccga
    16561 ttactacaaa gattaacgtg accacattca aaaacattaa aagatatgct gataatctca
    16621 tcattttttt agttcactta ctggtaatct aaacatttga acgattgcac tggaaatacc
    16681 ataattagca atgacaaaca aaaaatacgc aataatttca cttacaccta gatagatcag
    16741 taaaataaat aagtcactta acattgttag tttcctccca gtatatgatt ttcatttttg
    16801 ggaagtcttt tataatccaa ttcctcaaaa aaaggaacca tagtgtcact aatataggtt
    16861 ttagtttcag gtaccgccaa aattccccaa tcaagaattt cttcccatga tacatcatca
    16921 aattctaaaa tattatgatc aactgaccta ttaccaagtt catatccacc aaagatcacc
    16981 atattatcaa tcatgtatag aatttcatca ggcgaaccat gagttaatgt ttcgtcctct
    17041 tcaagcagtt cgtttaatct ttgtttgtat tcctctcttt tcatactttt atcccttctg
    17101 actcattttt ttgaatttta acatttttaa cccaagcatg actatcttta catgctatta
    17161 atttttatct ccattttgat atttctgttt ttttctactc accaatcaac cgtaaatcct
    17221 caatattctc accttcaagc gaatatgaat atacttcgcc gtaaatattt tctataacta
    17281 cgacttcttc ttcaaagtct atggactgca catcaaacca ttctcctccg ccaaattcgt
    17341 ctatgattag tacctgcaat attttattta ctgccatttc aatttcccct tataccattc
    17401 tatgtcttcc aaactatttt tcttctttcc ataccaaggt ttcacgtatc tcaaaatttt
    17461 ctttaaataa gtgttccggt acttttataa ttaactcttt tcctactttt atcagatagt
    17521 ctttttcacc taatgagatt tgaccagtcg gtaactgtat agaaactctt t
//
LOCUS       DAFLVO010000060        17027 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.060, whole genome shotgun sequence.
ACCESSION   DAFLVO010000060 DAFLVO010000000
VERSION     DAFLVO010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17027
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.060"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            288..695
                     /locus_tag="L1U99_002099"
     CDS             288..695
                     /locus_tag="L1U99_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212632.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            709..1110
                     /locus_tag="L1U99_002100"
     CDS             709..1110
                     /locus_tag="L1U99_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212633.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1112..1483
                     /locus_tag="L1U99_002101"
     CDS             1112..1483
                     /locus_tag="L1U99_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212634.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1519..1818)
                     /locus_tag="L1U99_002102"
     CDS             complement(1519..1818)
                     /locus_tag="L1U99_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212635.1"
                     /translation="MLFNETQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(1824..2054)
                     /locus_tag="L1U99_002103"
     CDS             complement(1824..2054)
                     /locus_tag="L1U99_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212636.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(2490..3056)
                     /locus_tag="L1U99_002104"
     CDS             complement(2490..3056)
                     /locus_tag="L1U99_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBN1212637.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(3056..4012)
                     /locus_tag="L1U99_002105"
     CDS             complement(3056..4012)
                     /locus_tag="L1U99_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBN1212638.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(4012..4668)
                     /locus_tag="L1U99_002106"
     CDS             complement(4012..4668)
                     /locus_tag="L1U99_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBN1212639.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            5038..7056
                     /locus_tag="L1U99_002107"
     CDS             5038..7056
                     /locus_tag="L1U99_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBN1212640.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    7126..7332
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            7483..9897
                     /locus_tag="L1U99_002108"
     CDS             7483..9897
                     /locus_tag="L1U99_002108"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBN1212641.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            10245..11798
                     /locus_tag="L1U99_002109"
     CDS             10245..11798
                     /locus_tag="L1U99_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBN1212642.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(12179..13963)
                     /locus_tag="L1U99_002110"
     CDS             complement(12179..13963)
                     /locus_tag="L1U99_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1212643.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(13978..15699)
                     /locus_tag="L1U99_002111"
     CDS             complement(13978..15699)
                     /locus_tag="L1U99_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1212644.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            15799..16560
                     /locus_tag="L1U99_002112"
     CDS             15799..16560
                     /locus_tag="L1U99_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBN1212645.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         5626 a         3022 c         3301 g         5078 t
ORIGIN      
        1 ttgaggggaa gtacatatag ttgttgatat agttgctaat attgttagct aatttgttag
       61 taaaactgta tacgaattta gatagtaaaa aaacagtttg ttccttatat agaggcactt
      121 ttactactga ttaaatgtca gatatgctta caaatatact tataaatatg cttacaaaat
      181 tagctaatat ttccgttgac aaagctttgt tactattgtt aaactaaatt gactagcaaa
      241 agtgaaacat aaatttatta aataaatgta aaaattagga gaaatcaatg tcttatagag
      301 tacaattaat aatttcagaa gatgtagaaa gtcagcaatt tggcactaat gttattaata
      361 aagtaattaa tccagctctt tctattaatg cgcctttaat tcctactgct ttatcatttt
      421 ctgtaacagc tgtggtgtct gagatagagg atacagaaaa gataaaaata gtagaaattg
      481 aagttttaaa caagaatgaa aaacaaattt tttctacggg tgaagtatcg gtaagcttgc
      541 ctcctcaagt taacgatata aactttaata taaacgccag aaatgtcttg gttgaagaag
      601 caggagagca ttatgctgtt gttaaattta atggaactga gattggaagg caaatctttg
      661 atatcaaggt caacaaacca gtggaaaaaa attaaggaga cgatacggat gcttgatata
      721 gtaccatcaa atacacatcg gagtggtagc ttaataaatt ttgctgcgat ttttgcttgc
      781 gcatcggtaa ttctagcatc tccagttgtt gtggatgcaa gttctactcc gaaaactaaa
      841 aatgataatc aacttgtaat tactacaaaa aatgagatta acacaatttc aagtaatgat
      901 ggcaaaattt ttgatgtgat aaatacggtt ttaaaaagaa aagctgaaat caatataaaa
      961 tatgatgaag atttaaactt gtatttcttt gttatcaaaa caacatctga attgttttcc
     1021 tcagattacg atgttttgga tactctcgat aatgtattat ctgactataa atatatgggg
     1081 aaatctgtag tagcaacttt gggggaataa aatgtttgac tttaatgaat atttatctat
     1141 ttccaaacaa attgaatcag atgataaata taattctaaa gaatcttata gaagaactgc
     1201 tgtttcaaga gcatactaca gtgcttttaa aaaatctgat gagtatttga aagaaaatta
     1261 tgatattatt tataatggaa gtagcggaaa aggaagccac caaaccgttt ggaatttgtt
     1321 ttcaacagtt aaggaattga ataccttagg aatacataat agtgggtata gaatgttaga
     1381 gaaaagaaaa tgtgctgact atattcctaa tgaaaccatt acgaaaacag atatggcgct
     1441 gatgaatcga gaagcagaaa aaataataaa caaactcacc taatgaattt caagcgagtt
     1501 tgtttgttat ttttttattt aatctttgta tctttctgga tcaacgaaag tatactttat
     1561 atagtcataa cgccgatgat cgctacgtgc gtccggcacg tcagtcacga tatcaaacaa
     1621 aaagtataca cccttcttca ttctagtttt cgcagcagga attttgaaat agttcttatt
     1681 agaatagtag agattgatta ataagctatc ttcgattgct aaaaagaaaa cttctgaatt
     1741 ccatacttta taaaaatctt tgataaatct attcgaaggg tcaaatttaa accataattg
     1801 tgtctcatta aaaagcataa ccattactcc gatctgtttt taaaattagt ttctacctct
     1861 aatatatatc gagtttttat tttgccttca gagaatactg tttctttttt tgcagttaca
     1921 ggttgtttat tttcggaaaa agctaatata gctaagattg aaacatccat ctggaattta
     1981 tcttttttac tgctttgatc ataaaagtct gcatattcat cactgatatt ttttctaata
     2041 aattcttcca tcataaaaat cacctcaaaa cgattatacg aacttacgtt cttgttgtaa
     2101 agcgatattt gaggggcaaa aaaggggcat aatttgactg atattaagtt agctattgat
     2161 atatgaatga catacaaaaa tataaaatct tttaaaaatg cttatatatc aatgtttttg
     2221 ccattctttt atatatctgt tatatgtcaa aaaaatgtgt tcaatttcaa tttgtatttg
     2281 aataaagagg ttgtgaaaaa gctgtcctgc atcaagtaat aagaacagcc aatcaaaaac
     2341 agcttctcat gtttttgatt tggttggact tattaccgca gatataagct tttgagcacc
     2401 gtgaataaag aggttatgaa atcaacgctc taacctgagt attagagaaa aaaacgcaaa
     2461 acatatcatt tatgttttgc gttttttatt tatctttttt tctcaataca atataaaata
     2521 ggcggctggt tcttttggtt gataaaccga taattcagca cattatatgt ttcctgtggc
     2581 agtttggaac aaaaagaatc aaccatatcc agttcttttt ctccaccttc atgaccatag
     2641 tagacgacaa ggatcaatcg tccgcgaggc acaagtcgtt tcaatatttc ttccatagct
     2701 gtgcgtgtag tctctggcat agtgatgatt gctttatcac tttttgggag ataccctaga
     2761 ttgaaaatcc ctgctttgag attttgttgt tcagctatca cttctcctaa cgtttcgtgg
     2821 ccttgtagaa acaatgagac acgttcttct aactgacgct gttctagcct ttcacgagta
     2881 gcatcgattg cttgttgctg gatatcaaaa ctatagacat gaccagtttt tccgatgtgt
     2941 tctgctagaa aaaccgtatc gtggccattg cccatcgttg catctacgac gtgatcccct
     3001 ggttgcaaga tttcttgcag taatgtatgg ctgaaatgca aagcagtttg caacatcaga
     3061 cgctcacctt tttccgtaca tcatattttc cttggaagct atctctgcga agaagttctt
     3121 catcaattgc attcaagact tcccattttt tcaagctcca cattggtcca atcaaggaat
     3181 cccacggcgc atcccctgtc aaacgatgga tgatgatctc ttttggtatc atttccagct
     3241 ggtcgcaaat gacattgaca tagtcaggac ggctcattaa ttgaaggcga ccttcatgat
     3301 agtcccgcaa cattctcgtt ttgcgcatca gatgcatcaa atggagcttg attccttgga
     3361 tatctgaatc taaaatggtg cgtctgacat tttctttcat catttctaaa ctttcgcctg
     3421 gtaatccgtt gatcaaatgc gtacaaacac ggatattatg tttgcgtaat ttagccacgc
     3481 catctaaata agtttgataa tcatgtgctc ggttgatcag ttttgaagtt tcttcaaaag
     3541 ttgtttgcaa tccaagttct acccataaat acatccgctc gttcagttca gcaaggtaat
     3601 caactacttc atctggcaga caatccggtc gtgtaccgac tgataatcct acgacacctg
     3661 gtaaattgac tacttgctca aatcgttctt tgattatttc aactggcgca tgggtgtttg
     3721 taaaattttg gaaataaacg atgtattgtt ggacatgagg ccatttttga tgcatcatgt
     3781 cgatttcttt ctggaattgg attggaagag ggtcttcagg tgcaacgatc atgtctcccg
     3841 aaccagatac actgcaaaaa gtacaaccgc catgggcaac agtcccatct cgattcggac
     3901 agtcaaatcc tccatcgatc ggcaccttga aaattttccc gccaaactca tttcgtaaag
     3961 cgtaattcca agaatgatat cttttatttc cttctgaata aggaaaagtc attaaaagtc
     4021 cttctttctg taagagttat ctatttgttt tcttttttct ctatacactg gataagtcag
     4081 gcacagccaa gaaagactga gtaagtaacc gccgatgata tcagtaggaa aatgaacgcc
     4141 cagataaatg cggcttatcc cgacacttac tataataaac atcatcagca attgaagcaa
     4201 tgtgcgtaag gttctttttt gaacaaaagc tggaagcaga aatagtaaag aaccgtaaag
     4261 aatcatactg cctgctgcat gtccactagg gaaactgtaa cttgtttcaa ctactaagtg
     4321 cgccaatgaa ggacgctctc gcatgaaaaa tagtttgatc accgggttga tgattccagc
     4381 aattacaata aatccagaaa cgaaccaaaa tgtttctgcc ctttttttct tataccacat
     4441 ccataaagcc gcacaagcaa ataaaatgat gacggtaaga ggattaccga atttagtcat
     4501 aaagagttgg tagctgttca gatcaggata agaagctctg acaatgcctg taaaccactg
     4561 atcgaaacca gaaagccacg acagatggaa ctttacgatc cagcccaaaa tgaaaaacag
     4621 gacaagaaag aagctaccag ccacctgaaa tgatgtttta tatttcatac aattcctcct
     4681 ttgaagcaat gacttattat agcatttttg gtccagcgaa aaaaacggta aagagataaa
     4741 accaatgtat gattcctctt tgaataacca atattcttat aaaaaaaata actgtaatcg
     4801 gaaagacatt ttttggtaat gcaaatgaaa tgttagggaa ataaaatcag tgtttttcga
     4861 aatcctttta aacaagaacg tagacgtagg aagaacttga aaatgaacag aagttgttca
     4921 ttacggtaaa ttacaatatg attacaaaaa acaacaaagc tcttaaataa cttttaataa
     4981 atattaagag aagttataat tattaataat agataaattg aagttggagg atagaagatg
     5041 gaaaacattg caagaaaaga acggagacgt ttagaacaga ccaaacgttt tcgaaaagca
     5101 aaacgagggg cagcaatcgt gggaactgcg atggtaggct gttctgtcgc tgccccatta
     5161 gtacagccgg ttcctgttca agcggatgaa acacctgttc agttcggcgc aagaatcaat
     5221 acagcggcat ttatcacaga aattgctact tatgctcaac caatcgctca agccaacgat
     5281 ctatatgcat cagtgatgat cgcacaagca gttgtagaaa gcggttgggg cagtagtgcg
     5341 ttatctcaag caccttatta taatcttttt gggataaaag gcagctatca aggacaaacc
     5401 gtctacatgg atacgcttga atttttaaat aatcaatggg taaataaaaa ggagcctttc
     5461 cgacaatatc cttcttttgc tgaatctttc aatgacaatg cctatgtact tagaaatact
     5521 tcatttggca acggttatta ctatgccggt acttggaaga gcaacacgaa atcctataca
     5581 gatgcgacag cttgtttgac agggcgttat gcgactgatc ctggttacgc aggcaaatta
     5641 aataatatca tcgcaactta cggattgacc caatatgata caccagctag cggaaacgca
     5701 ggcggtggag cgactacagg tggcaataat actggaagtg caggtagtac tggcggttca
     5761 agcaattctg gtaatacaaa ctcaggttca gcaacttcga ccacttatac tgtccaatct
     5821 ggtgattctg tttggggaat ctcaaataaa ttcggtatca caatggatca attgatccaa
     5881 tggaacaaca tccaaaacaa tttcatttat ccaggacaaa aactgacaat caaaggtagc
     5941 caggaaaatg gctcttcgac gaataattcc ggtaacaata ccaattcttc aggaaatgct
     6001 ggtacatcaa acggaggaca aacaactggt gcgaaataca ctgttcaatc tggtgattct
     6061 gtttggaaga tctcaaatga tcacggaatt acgatggctc aattgattga atggaacaat
     6121 atcaagaaca atttcgttta tccaggacaa cagctaatcg tatcaaatgg cggttcttct
     6181 aatgctggag caaatactgg ctcaaatact gggaatacaa gtggctctag ttcgtccagc
     6241 tcaagttctt ctaatacagc ttcaggaacg aaatatacag ttaaagccgg agactctgtt
     6301 tggagcgtct caaataaata cggaattacg atggctcagc taatccaatg gaacaatatc
     6361 caaaataact ttatctaccc aggacaacaa ctgactgttt caaacagtgg atcaacaaac
     6421 agcacgtcag gtaatacagg ttcgtcaacc aatacaaata acagcagttc agttaatact
     6481 ggcagcagtt cgtctcaagg cacttatacc gtgaaagcag gtgaatctgt ttggagcgtg
     6541 gcaaataaaa acggcatcac gatggatcag ttaatcgaat ggaataatat caaaaacaac
     6601 ttcatttatc caggacagca attgatcgtt aaaggtggaa cttcggcaaa tacaaataca
     6661 ggttcaacta cttctgcagc gaaaccaaat acaccgaata cgtctgctac gacaagtaca
     6721 tcatccactg gtaatacgat gtataccgtg aaagcgggcg agtcagtttg gagcgtagcg
     6781 aacaaacatc atatcacgat ggatcagtta atcgaatgga ataatatcaa aaataatttc
     6841 atctatccag gacagcaagt gattgtgaag aaaggttcat ctcaatcaac aaaccaacaa
     6901 tcagttactg gttcgaaaac ctatactgtg aaatctggag aatctgtttg gagtgttgct
     6961 gacagtcatg gaattacaat ggctcaacta atcgaatgga acaatattaa gaacaacttt
     7021 atttatccag gtcaaacgtt gattgtagct aaataaaata gctgttcgaa gaaataacga
     7081 ttgaattcca caaaaatatt tgttactata aggctactta aatatgacaa cacttgaaaa
     7141 ggaagtagta aaaagactga agtttcagag agcgcatggc tggtgagaat gtgcacggat
     7201 gcttttgaac tcgcctttga gttgcccttg ctgaataccc gagtaagcaa gcggcggtga
     7261 cggccgttac aacgttcgag gccttttcac taaggtaaaa ttaggtggta ccgcgtagat
     7321 tacgtcctat aaaaagagca atctttttat aggatttttt tatttctttt gtgaagtttg
     7381 agaaaacaaa gcaaaaggaa ataaaaataa acagattctg ccggtttttt cgttatattt
     7441 ataatagaaa caagtgtttt caatagaaca ggaggacagc aaatgagtta caatcataaa
     7501 gaaattgaga aaaaatggca aaaatactgg gcaaaaacga atactttcaa cacccatgat
     7561 gatcctgaaa agccaaaatt ttacgcactg gatatgtttc cctatccatc cggtcaaggg
     7621 ctacatgtag ggcatcctga aggttatacg gcaacggata tcctttcacg tgtgaaaaga
     7681 agtcaaggat acaacgtgct gcatccaatg gggtgggatg cattcggtct gcctgctgaa
     7741 caatatgcgc tagatacagg aaacgatcca gctgagttta cccaaaaaaa tatcgaaaca
     7801 ttccgacgcc aaatcaattc tttaggattt agttatgact ggaatcgcga agtgaataca
     7861 actgatccgg agtattataa atggacacaa tggatcttta cgaagcttta tgaaaaaggt
     7921 ctagcttatg aagcagaagt agcggtaaac tgggtacctg aattaggaac agttatttca
     7981 aatgaagaag tgatcgatgg gaaaagtgaa cgtggtggct atgatgtagt cagaaaacca
     8041 atgcgccaat ggatgctgaa aatcactgct tatgctgatc gcttattgga tgatctagaa
     8101 ttagttgatt ggccagaaag cattaaagaa atgcaaagaa attggatcgg tcgttcagta
     8161 ggagcaaata ttgaatttaa agtggctggt acggataaat cctataccgt atttacgaca
     8221 cgaccagata ctctattcgg tgcaacttac tcggttcttg cacctgaact agatcttgtt
     8281 agagaaatta cgacccctga acaaaaagct gctgtagaag cttatatcga agagacagct
     8341 aaaaaatcag atctaaagag aacggatctt gcaaaagaaa aaacaggagt atttactggt
     8401 gcttatgcaa tcaatccagt taatggcaag gaaatcccaa tctggatcgc cgattatgta
     8461 ttatcttcat acggcacagg agccatcatg gctgttccag cacatgatga acgtgacttt
     8521 gaattcgctc aaactttcgg actagaaatt cttccagtta tcgaaggtgg agatgttgaa
     8581 aaagctgctt acacagaaga tggtacgcac atcaactctg aatttctaga cggcatgaac
     8641 aaacaagaag caatcgataa aatgaatgaa tggctagaag aaaatggcgt agggaaaaaa
     8701 gaagtcagct atcgcttacg tgactggcta ttctcccgtc aacgttactg gggtgaacca
     8761 atcccaatca tccattggga ggacggaaca gtcacagctg tcccagaaga agagctacca
     8821 ttacggttgc ctaagacaaa aaacatcaag ccaagcggta ctggagaatc tccattagca
     8881 aatatcgagg agtgggtcaa tgtcgttgat cctgtaacag gtaaaaaagg ccgtcgcgaa
     8941 acgaatacaa tgccacaatg ggcaggaagc tcatggtatt acctgcgtta tatcgaccct
     9001 cataacaaaa aagaactagc agattatgaa aagttgaagc gttggctacc agttgacatc
     9061 tacattggtg gagcagaaca tgcggtactt catttactat atgcacgatt ctggcataaa
     9121 ttcttatacg atatcggtgt tgttcctaca aaagaaccat tccaaaaact atacaatcaa
     9181 ggaatgatct taggcgaaaa caacgaaaaa atgtcaaaat ctcgtggtaa tgtagtcaat
     9241 cctgatgatg tggtcgaaac ttacggtgca gatacactgc gcatgtacga aatgttcatg
     9301 gggccattag atgcttcgat tgcttggagc gaaaatggct tagaaggaag ccgtaaattc
     9361 ttggatcgtg tatggcgttt gatcgttgat gagaacaata aaatgcgtga ccgtatcact
     9421 acattgaatg atggcaagct tgataaagtg tatcatcaaa cagtgaaaaa agtgacagaa
     9481 gactatgaaa atcttcattt caatacagca atctcccaat tgatggtctt tatcaatgaa
     9541 gcctataaag tggacgctct gccttatgaa tatatcgaag gatttgttca actactcgca
     9601 ccgattgctc ctcacatggg tgaagaacta tgggcaatcc ttggaaatga tggtggtatt
     9661 tcttacgcac catggccaac atacgatgaa gcagcacttg ttgaagacga agtagaagtt
     9721 gttttccaag taaacggtaa agttcgtgcg aaaagcaatg ttccccgaga cttaggaaaa
     9781 gatgagctag aaaaagcagc attagccaat gaaatagtgc aagaatatat tgaaggcaaa
     9841 acagtcagaa aagttattgc ggtaccaaac aagttagtca atatcgttgc taattaattg
     9901 gctctttgtc aataaggact gatgagttgt gcaaaatcaa atctgggcca gaatgaactt
     9961 cattctgtct cagatttttt gttatttcaa attgattaat tgattgatca aaaaggtttt
    10021 gattttcatg ttctcaaaca cgttcaatgt ctttttcttc tgaatggtct tgtaagagat
    10081 ctctgtaatc atcaaatttt tgtctattaa tcttagtatt ttttgatgta taaactacct
    10141 gaaattgaga gtacatacca aattcataaa ttttttatta gtgggactag tgattgtatg
    10201 gattttgacg cataatgaat gaagtatgag aaaaggagag acaaatggat caagaactat
    10261 ttattatcga agtattatca gctaaacaaa aaattatcga gaaagcgaaa aaaagagcga
    10321 aaagaataat gttcaagctt ttaagcttag tatttttctc tggtttgctt tttttcggag
    10381 ctgtatcgtt cctatatcgc catatgagtg cagtagtccg ttcagctgaa gggatgcaaa
    10441 aattaaataa tttgtatcac ttttcgtggg gagttggcgg aataacaatt gttgtgctta
    10501 ttgtttttct tctacttatt tggctccgtt accatcaatt gtcgcgtcat ttcgatcaat
    10561 ggcttagtca aagagcacaa cagtttttac ataataaacc aacttctcaa gatgatgact
    10621 atctttattt tgagaagact tcgacgagtc aagcttttcg gatacaaaaa agtgattgcc
    10681 agttattgct gagatcactt gatgatttac ctatctactt aggcgaaagc aaatcaaaat
    10741 tcggaatgaa cacattccat atttttttac tagaaaacga acccagatgg gaaaaaagcc
    10801 agtcttcgcc tggtggatac ctgacaacta agatgagtac attagtcact ggttttttcc
    10861 tcattctttt agctggaaca atctattatg ggagatacac tcagccaaaa atgtcttctc
    10921 atataaatgc tgcttctcac atgacaatga actcaactaa cgatacgcat atacaaaaga
    10981 caaatgaagg gttgttagct gatcctaagc aaaaggtaaa tttgacaaca caaaagataa
    11041 atgatctcaa acttgataca gagacgcact ctctctatat gacaacagat agtggtgcta
    11101 attgggtatt tgtgccgatt gattcgcaat ggttgcgttt tggcgaatac accctgacaa
    11161 cggggctgat tcctgaaggt tattggatgg acaacacata tgatatttcc gccgatttct
    11221 catggtttat ctattcttct ggggatgatg tacgtctgct gacttcaaga gataatggta
    11281 aaacatggca aacgtctatt atcacccaat cagttcagcc gatacgttat cgaaaagcgg
    11341 tattttatgg caacgatggt ctatttatct gtacatcagc cagtgggatg tctgcagaaa
    11401 ctttgtacat ttacactact atggatggcg gaatcacttg gataaaaagt ggaagtacaa
    11461 tgatcaatca gccagtacaa aatgtcagct tcgttacaac ttctttaggt tttgtttcga
    11521 cacgtgaaag tttgttttat acaaacaacg gaggacgctc attcaaagaa tcagttctgt
    11581 cgattccgga aaactatcag acagggggga tagatctttt tcaatcacca aatgaagtta
    11641 ctcaaataag cgcgaatacg ttagagacaa aattttattt gttgaaaaaa ggaccaatcg
    11701 atgcagggaa aatgtttgcc tgcctcttcc gttcaactga taacggggaa acatggcaat
    11761 tcgttcagca actatcgcaa gtagaacaag gagattaaag aagagagatt gtgagcctga
    11821 cgttcagcac cgagtcacaa gaaacaaatt caaaaaacag cttctcatat ttgttgaata
    11881 gtgtaactcg tgattcggag ttgacaagag caacaagaag cgattttgaa gtatagcttc
    11941 tcgtatttta caagatcgtg tcttattgcc gataggttgt ctcttgaaca ccgtttattc
    12001 gtaaaaaggg attgtgacaa gtcttttgtc actacttacc gaacgaaact gaaggagcta
    12061 tccaaaaagt atcattagta ttattctttg tgtttctagt ggcaccacta gtacatttaa
    12121 aaaagctatc gatcatggac taatcataca tgatcgatag ctttttagat aatgtttgtt
    12181 acgctatctg aaattgacta ttataaagac tggcataaag cgttggtgat tggagtagtt
    12241 cagaatgtgt tcctttttcg acgatatcgc cattcttcat tacaaggatc atgtctgcat
    12301 tttcaatcgt tgacaaacgg tgtgcaatca caaaacttgt cctatctttt gtcacagctt
    12361 ccattgcttg ctgaatcaat gcttctgttc gtgtatctac gctagaagtt gcttcatcta
    12421 aaataacgac aggaggattc gctagaatga ctcgagcaat tgtcaataat tgttgctgtc
    12481 cttgagataa cgtgccgttt tcgctagaaa tgatcgtatc atatccgtct ggcagtgttc
    12541 gaataaagtg atcacattgt gcgatttcag ccgcttcgat aatttgttct cttgtggcat
    12601 ccattttccc gtaggcgata ttatcagcta ccgttccttc aaacagccag gtattttgta
    12661 aaaccatccc aaaagaacga cgtagttctc cacgtgaaag cttggtaata tcaagaccgt
    12721 cgaattcgat ctttccttta ttcagttcat aaaaacgcat cagcagattg actaaagtcg
    12781 tttttcctgc accagttgga ccaacgatcg ctaccgtttg ttttggcttt actgaaaaat
    12841 cgacttgatt catcaatatt ttatctgatg tgtaaccaaa ctgtacattt ttgaaagcta
    12901 tttttccttt cggttgttct aaaagtcttg catctggaag gtctggaatt tcatctgttt
    12961 catctaatat ctcaaatatc ctatcgattg ctgccattgc ggattggatc gagttgatca
    13021 cataagaagc ggtagaaatt ggttcagaaa tctgattgat gtactgaaga taagcttgta
    13081 agaagccgat cgtcacacca cctgatagaa caagcatagc accgaatacc gcacttatga
    13141 tgaaggcgag ttgattaatg aaacgaatgg ccggatagat agcacagttc ataaattgag
    13201 cacgtttaaa agcgttgtat tgctttttat ttacttcgtg tatagcagct tctgcatgag
    13261 cttgctgatt gaatgttttg accactagat taccagctaa gatttcttcc attcgattat
    13321 ttaaaacacc cagttcatac tgattctgtt cagaaatctg tttgtttttg ttcgcaatct
    13381 tagttgtaac aattgaactg ccaacgatca gcaataagac gagcaaagta agcttgcttt
    13441 cgatataaaa cagcatcaga ccagcagcag ctattgttac gacagaagta aaaaattgat
    13501 tgatacctgt caataacact tgagaaagtt gattgagacc ggtagttgtc cgactaatga
    13561 tgtcacctac ttgatgattg tcaaaaaacg acatcggtaa tgttttgaat ttttttgtga
    13621 tttcttttcg caccctcaat gtgatctttt cgcttaacgc tgccattgtc cgttcctgaa
    13681 taaatgaagt gatgctgctt aagactgaac agccgatcag caataagaca gggaacaaca
    13741 atgcttgttt gatatcactg aaagaaagct gtccaatacc tgtttttctt atttctgata
    13801 agagatcatc gatcccgatt cccatgatca agggcatggc tacgactaat aggttcccga
    13861 ataaactgca tagaaacaat ccgtaaaaat atttatgttc aggtttgatc attttccaaa
    13921 aacgtatcaa agcacgcgtg ttcaacgttt ttttcttttc catcgtatcc cttctttcta
    13981 tattccttgt gattttgcaa actcctgata agtttggcaa ttagacagta gttcttcatg
    14041 agtaccttgt ccaacgattt ttccttcatc taaaacaatg atgttatctg cttgttggat
    14101 tgtactgagg cgttgagcaa caatcacgag agttttctcc gacatgtgtt tatgaagggc
    14161 tgctcttaat gctgcatctg ttttatagtc taaagcggag aaactatcat cgaatacata
    14221 gatctctgct ggtttgatca acgctcgagc aatacatatc cgctgtttct ggccccctga
    14281 ataattagaa ccgccttgag caacaaagct gtccaatccg tcaggaaggg tgtccactag
    14341 ttcttctaat tgagcgatct tgatcgcttt agacaactct tctgttgagg catattcatt
    14401 tcccatctgc aagttgctta aaattgtccc gctgaataag aaagccttct gagggacata
    14461 actgatgtgg gagcggatct gttcttgagt catttgagta agaggaatac caccaagggt
    14521 tacttttcct atcgtagggt cactaagtct caagagaagt ttcgccaaac tactttttcc
    14581 agatccggtc ccgccaacga tcgctgttgt ttttccttta ggtattgtga aatcaatatc
    14641 ttctagaact ggatcagaga tttcagtata tttaaatgtg acatgttcaa aagcagctgc
    14701 atttgtctga tcaaaggttg gttcagctac tgttttgatc gtctcttcct caatttcgat
    14761 ctctgcttgc agtatttctt ctatccgtcg taatgaggca aacgatttag ggataatgac
    14821 caataccata gctgcgatca tcaagtaagc aagtgtcagc atagagtatt cgactacagc
    14881 agtcacgaca ccgatttgta atgctccttc tgctacaaga tttccgccaa accacaaaat
    14941 agaagcataa acgattccca tgagcaaaaa agcaattgga gtgacccaag caaatattcg
    15001 gttcactttg atcatttgat tagcatagtc agcaaagctc ttattcgttc gcttttcttc
    15061 atatgattga ttatcaaagg cacggatcat attaatccca gtaaagaatt ctctcaatgt
    15121 gatggtgatc cgatccattt ttggctggat actcaaagat aaaggtgccc ctcgtttcat
    15181 cagtcgataa acaatccata cataaaaaac aacagagatc aatgtaaccc atgttagtaa
    15241 tagagaataa cgaaacatca tgagaatggt gaaaacgcaa ataaccggtg ctggtaagat
    15301 catttggcaa aataaaacaa tcatttgctg gacattatcg acatcattcg tcattcttgt
    15361 caaaagagat ccagaactaa aacgactgat atccttcatt gacagctgtt ggaatttacg
    15421 gaaatatttc tcccgcgttt ggaatccaaa cctagcggaa gccaatgctg aaaagtaact
    15481 agaggcaact gcagcgattg ttcctagaaa cgctacaagc agcatttcaa ctccaatttt
    15541 ttttataact gaggcttcgc cacttgctat acctgtgtcg atcagctttg ctactaattt
    15601 tggtacacct aatgtaccgg cgatttctaa acagatcatc acaaaggtaa ggagagcgag
    15661 tcctttgttt ttctgtaaga atgtttttaa gatagacata ttattcctcc tttttgcctg
    15721 atacttttcg attctatacc ttcaagtaac ttgaaggtca atagaaaaaa gaataaactg
    15781 aaaaagaggt gagaaaaaat gaaaaaaatg tatacgattg gccaagtatc ggaactattt
    15841 gatttgccaa aatcaacgat ccgctattgg gatgaacaag gattaatccg ttcaagtaga
    15901 caagaagaga atgattatcg attgtttgat atcgatgata tttttatgct ttatgatatc
    15961 gttttttata gaaaattaga tataccgatc aaacagatga agaatttata tggaaaaaca
    16021 ttgacggagt tatatgagac acttgatgaa acagaaagaa gaatccataa agaactggtg
    16081 gtgatgaaac aaaaacaaaa agagataagg gagcaaaaaa aacagttgaa attgatgatc
    16141 gatacaaacg aggaagaatt tcctgtagaa gagatccctt ttgactgtat gatctcaacg
    16201 gagtttgaag atattgtgga aatcaaaaaa tttctaccta actattcaag ctttgggatg
    16261 atgagtatgc cagcttccag ttcacagacg atgtatggat tttttatcga ccctagtgaa
    16321 gtacatttat ttactcaaga cgtgatttgg gagaaaaaag atacggctgt ttatcgtcga
    16381 ttcttattga aatccgagat gaaccatgcg gaacgtaata atattttaga aatcagagaa
    16441 agaatgtatg aaaaaggatg gaaaacagga gaagtgatcg gccagtatct attgacgaat
    16501 acggatgaaa acaatatcag aactgaatat tatcatgcat ggatagaaat gaaaaaatag
    16561 gaaatatgtg tttaagataa ctcgaaaatg atggttgttt tagttataaa gaaaaatttt
    16621 ctggttcgat tacgggttta atgtggggga ttattagtcg tggatagata gaattttagt
    16681 tttttagagg aaatatgtct ttaaaaatgg aatggttgca attcttagcg atatatacga
    16741 tgtaattgtc ctcttaaaaa agtatggaaa aataattgta ttgggtgtta tgtataattc
    16801 atggtgaact gagactaatg agaagaaaaa ttcatattgt tatgagtgag attgtatcag
    16861 atgagaatga taaattaaat aggtgcataa aagcattaca cttaaaatac attgttgctt
    16921 acattattac aatatgttaa taaggcaaaa ataaatagat ggattgaata aacatatttt
    16981 ttaatcaaat agtccctact gtgactttcc tcagctatcg gtgatac
//
LOCUS       DAFLVO010000061        17007 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.061, whole genome shotgun sequence.
ACCESSION   DAFLVO010000061 DAFLVO010000000
VERSION     DAFLVO010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17007
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.061"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..126)
                     /locus_tag="L1U99_002113"
     CDS             complement(<1..126)
                     /locus_tag="L1U99_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HBN1212646.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
     gene            complement(230..541)
                     /locus_tag="L1U99_002114"
     CDS             complement(230..541)
                     /locus_tag="L1U99_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBN1212647.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(543..740)
                     /locus_tag="L1U99_002115"
     CDS             complement(543..740)
                     /locus_tag="L1U99_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HBN1212648.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1134..2861)
                     /locus_tag="L1U99_002116"
     CDS             complement(1134..2861)
                     /locus_tag="L1U99_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HBN1212649.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2854..4047)
                     /locus_tag="L1U99_002117"
     CDS             complement(2854..4047)
                     /locus_tag="L1U99_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HBN1212650.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4234..4878)
                     /locus_tag="L1U99_002118"
     CDS             complement(4234..4878)
                     /locus_tag="L1U99_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1212651.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4972..5106)
                     /locus_tag="L1U99_002119"
     CDS             complement(4972..5106)
                     /locus_tag="L1U99_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBN1212652.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5108..7240)
                     /gene="feoB"
                     /locus_tag="L1U99_002120"
     CDS             complement(5108..7240)
                     /gene="feoB"
                     /locus_tag="L1U99_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBN1212653.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7237..7710)
                     /locus_tag="L1U99_002121"
     CDS             complement(7237..7710)
                     /locus_tag="L1U99_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBN1212654.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8111..8335
                     /gene="nrdH"
                     /locus_tag="L1U99_002122"
     CDS             8111..8335
                     /gene="nrdH"
                     /locus_tag="L1U99_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HBN1212655.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8494..10653
                     /gene="nrdE"
                     /locus_tag="L1U99_002123"
     CDS             8494..10653
                     /gene="nrdE"
                     /locus_tag="L1U99_002123"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBN1212656.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10703..11668
                     /gene="nrdF"
                     /locus_tag="L1U99_002124"
     CDS             10703..11668
                     /gene="nrdF"
                     /locus_tag="L1U99_002124"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBN1212657.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11757..12896)
                     /locus_tag="L1U99_002125"
     CDS             complement(11757..12896)
                     /locus_tag="L1U99_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBN1212658.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13205..13918)
                     /locus_tag="L1U99_002126"
     CDS             complement(13205..13918)
                     /locus_tag="L1U99_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBN1212659.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14172..14873)
                     /gene="nagB"
                     /locus_tag="L1U99_002127"
     CDS             complement(14172..14873)
                     /gene="nagB"
                     /locus_tag="L1U99_002127"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBN1212660.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15107..16639
                     /locus_tag="L1U99_002128"
     CDS             15107..16639
                     /locus_tag="L1U99_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBN1212661.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16830..>17007)
                     /locus_tag="L1U99_002129"
     CDS             complement(16830..>17007)
                     /locus_tag="L1U99_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1212662.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5278 a         3495 c         2910 g         5324 t
ORIGIN      
        1 tgaaaaaaca cattccacta aatttgatgc cggttttcct tgaggttttg ttccagcacc
       61 tcctttaatt tttttaagct cttgatctga acattgttta gcatttagtc tatttttttc
      121 ttccattacg attcccccta caaactataa atacttttat gtcactgatt caatatacct
      181 atttttctaa tcaaaaaatt ttgagacata tttaatatta taagtatcat taaaattgag
      241 atttatctcc ataatctgct cgatataaac catttattcc agcagttctt ccaatttcac
      301 tcaaatttct tattaattcc tcttgatatt cagtgaatct tattttatta gtataagcag
      361 taaaatatag ataattcacc aatctattta ttaaaggact gggatctaat tcatattttt
      421 gtttttctaa ttttaaatat accttttgta aaacctcaag aatatcagaa tatttaggat
      481 ctttacttat agatatatca ttatataatt catgaacaat ttgcttagca ttttttttca
      541 ttttagcact tccctggaat tgctccacct aaaaaaccac ctatagacat tcctgcaata
      601 caagtagttg ccttggccca atcgaccgta catttatttt tagtgcaata cactccattt
      661 ccataatatt ttccactatg agtggtaccc ccatagataa gttgtgtctc tttaatagac
      721 aaaattttta aatgtttcat aatctaatca cccctaaatt aatgttttta gactattatt
      781 ctaacattca ttaaatttca aaaaacaatt ccttcttgaa acgtagcaaa ataattcctg
      841 aataagaatt taatcacttt taagtatata aactatgtat attctttaat attttttgag
      901 aatgcacttc gtacataata aactttaatc acattagtct ttcataccta cgatcgatct
      961 ctttgactcg cacccataaa ttcataatag tttgtcggcg tctttgaacg tttcgaagat
     1021 gagctacgca ttctcttttt ttatagacaa aaaagataga gacgaacatg gagcttccaa
     1081 atttggatat ttgatccaat tttggaagct ccatttattt cgtgtctgtc tttttatttt
     1141 ttccagcttt cgactaattc ttggttctct ttgatccagt cttttgctgc ttgctgtgga
     1201 tcttttccat tgttgatttc caacataact ttttccatat ctttttctga ccaatggaaa
     1261 ttgtctaata ctttgtaagc ttctggctgg tcttctttca atccttttcg aaccatcgta
     1321 tggatctgct cttcgcttcc cattccgttt tcaggatctt ctaagtattt cagatcatat
     1381 ttggcaaaca tccaatgagg tgtccatcct gtaactacaa ttggttcgtg ttttttgatc
     1441 gcttgaccta gtgcaacggt cattgctcct gaagaagatg tctctacttt ccagtctttc
     1501 aagttgtcat atttttggat cgtgttttca gcagccgtaa ctacaccagc tcctggctcg
     1561 attcctatga ttttcttacc tgcctgatcg gttaactcat cgatcgaatt tacatccatg
     1621 taggctggca ctgctaaacc aacttttgct cctgtcaaat tggcacctag gtcttcgact
     1681 tgatctttat attgtgcata ttgtgaacca tgagttttag gtagccaagc tgaaaccatg
     1741 gcatctgact cgccatttga aacagatttc cacatgattg aattatctaa tggcgtcatc
     1801 gttacatcat agcccatttg tttcaatact tcaccgacta catttgttga agcaacttct
     1861 gtatcccatt caacataaga taagttgata cgttttgttt ctttggcaga tgaaaaactc
     1921 cctataccaa tcgcacctaa gatcactact actacagcac caatgatcag tccttgacgt
     1981 tttttacttt tctgtgttgt tgctcctgca gcttttttat tgtttggctg gttcaaatgc
     2041 tgtgtaaaac ggtcaatgat gattgctaag ataactaatg caaccccgtt gacaaatcca
     2101 ttcccgactt gtgctctttg caatgctgat aatacgccgc gtcctaagcc gggtgcaccg
     2161 atcatagagg caataacgac cattgaaagt gacagcattg ttgtttgatt gatccctgcc
     2221 atgatcgtac ttttagctaa aggcaattct agtttgaata gtttttgacg acttgtgctc
     2281 ccgaatgaat cagaagcttc tactaattct ttaggaactt gtcgaatccc taaattcgta
     2341 aaacgaacgg ttggtggcag agcaaagatg actgaggcaa atacccctgg aaccatcccg
     2401 ataccgaaaa atgcaactgc tggaatcaaa taaacgaatc ctggcattgt ctgcataaag
     2461 tcaaggatcg gtttgataat actttgggct ttactgcttt ttgccatcaa gatccctaat
     2521 ggtaccccaa tgatgatcga gatcacacta gataaaagaa caagtgtgac agtattcatc
     2581 aaatcattcc atagaccttg gttataaata aaccatagac cgattaatgt gaacaacgta
     2641 agtcctggac gtttcttaga aataaagaaa gctgctaccg tcaataacaa gataaacaaa
     2701 ggagctggaa tcactaacag taaatttgta atccccgaca tcactgcctg tccaatcgtt
     2761 tgtaaaaatg aaaataggcc agaaaaagtt gtcgtaaacc attctgtgat attttctacc
     2821 cagtttgcca ctggtaattg atagttcaat agattattca tgttcactca cctcgcttgt
     2881 ttctgctaat gcttcaatca cactacctcg gatgacgaca ccttttaatt ttccatcctc
     2941 tacaactgca agtggagtcg gtgagtcata aataatattg aaaatatcac ttaccaccat
     3001 gtctttccca atcaccgtca cattttcatc taggaagtcg atcaatggac gtttttgctt
     3061 cctagcttct aacgcttgat ctgcagtgat gatccctttc aggtgtctct ttctgtcaac
     3121 agccatcagc atgctgactt cttcattacg catccttgtc aatgcaacgt ttggtccatc
     3181 agattcgata ttcgtcgtca atgcaggtac catgatgttt tgagccgtaa gcactttgga
     3241 acgatcgact tcttccacaa attcacgtac ataatcattt gctggattgg tcaatatttc
     3301 ttcacctgtt ccgatctgca tgatttcgcc gtctttcatc aaggcgattc tgtccccaat
     3361 ccgtaaagct tcattcaaat catgggtaat gaaaataatc gttttttgaa cattggcttg
     3421 caggtccagt aattcgtctt gcatttctcg ccggatcagc ggatcaagag ccgagaacgc
     3481 ttcgtccatc agcaagatct caggatcatt tgctaaagct ctggctaggc caacccgttg
     3541 ttgcatccca ccagataact gactaggata ttggtcttta aatgaaagca aactagaatt
     3601 ttctaatgct ttttctgctt tttcttgtcg ttcttcttta ggtacaccac ggacttctaa
     3661 cccgtattct gtattttcca agatcgttcg atgtggaaac agaccgaagt tttggaaaac
     3721 catattgatt ttatgacgac ggacttctcg caattcttct ttgcttaact tcgatacatc
     3781 ttctccatca atatagatac tgcccgaagt tggctcaatc agacgattca atagacggat
     3841 caatgtggat ttcccactcc cggaaagccc catgatcacg aagatttctc cttcttttac
     3901 gtcaaaattc acgtcataca caccaaccgt tgcaccggtt ttctttaaaa tctccgtttt
     3961 cggctggtga tcattcatca tatctaaagc ggcttgtgtc tttttaccaa atatctttgt
     4021 taaatgtttt acttctactt ttaccaaaca aattctcctt ttttatgtaa attcattttt
     4081 ctttctgaaa aaagtgacca cactatgtta acatcatgta gtcactttgt caaaaatgaa
     4141 agaaatttgc ttgtccaaac tgaaaaaaac ttggctaaat ctttgtaaat aaaaggttta
     4201 gccaagttaa tattttttta atatttcaca caatcattct gcaagctgat gctccgggta
     4261 aaaaaagttt gtcatacgct gtagtgtata ttcatttcca ataaaatgaa cgatgtcccc
     4321 tgccgtaaat ttagcatagg ggccaggtga aacaagcagt tcttcattat gagaaattgc
     4381 gataactgtg gcgccagtcg cctgccagat attcaactcg ctaattgaac ggtccagatg
     4441 cattgctttt tctgataaag ataattcaaa cggaagtaaa ggattcatct tatgtattcg
     4501 cttcgtttga ttgaccagct gatccaataa ttgagaaaaa tgattcagct catcttgttg
     4561 cttctccaca cttgccatga tttctgcttt tgtatcttgg atggattgta catcttgata
     4621 ttgcaatagg aaatcttttg ctttttcctt cgaagcaaca aatgccccac ttccatgccg
     4681 tacttccatg attccaagat ctaccagcac attgatagcc ttgcgggtag tctcaggaga
     4741 agcattgtac gtactggcaa gtgttgagcg ggcatggatc ttctcaccca ctttatatcg
     4801 gttttcaacg atacgttcgg ctaaatcaac agcaatctgc tggtagcgcg ggcggacgat
     4861 ttttttcttt ccagacattt tctttcctct ttcttttttt actttccctc atcttactat
     4921 gctctagcaa aataagcaaa aaaggggaga atagcctctt gcaacgactg atcatcgctt
     4981 gatctgttcc ttttttactg ggcaagctgt ttgacagtca tcacaattct taccggattt
     5041 taaacgagta tagacaattg cgcctgcact tccaaagatt aacacactta ataagaatgt
     5101 cgccatccta ttcctctcct tctaatgaca atatagtata aaactggttc ttggattttg
     5161 gctgacggaa caaaacataa acgagtccta tcatcagtaa aatagcaaga tacgtcccta
     5221 acgctacctg tccaccctcc aataagtgtc ccaactgata aatcacaaaa ctaactaaat
     5281 aagctaaacc gcattgatag cctatggcga tccaagtcca tttcttggca ttcatttccc
     5341 gatggatagc cccaattgcc gcaaaacaag gcgcacaaag taaattgaag gctaacaatg
     5401 aataagctgc tgcgggagta tatgtgtgtt gtagcacttg ccagatttct ctgccatttt
     5461 cggatacttc cgcatgacca aacaaaatac caaatgtgcc aataatattt tctttagcga
     5521 ccaatcctgt aatcgctgcg actgttcctt gccagtttcc ccaaccaagc ggctgaaaaa
     5581 caactgccag gattcgcccg aaaaaggcta agatactttg gtcttcagaa acaggttgag
     5641 cataaaaatt ataagaagag ctgaaccaga tcacgatact agaaacaaag ataatcgttc
     5701 ctgctttttt aacaaaagac ttgctgcggt cataggtttg tcttaggacc gctgaccatt
     5761 gaggaaaatg atatgcgggc aattccatga taaaaggagc tgtatctcca gcaaacaaac
     5821 gtgttttttt caagctgatt ccagagaaaa taattgcagt cataccaaga aaataggcag
     5881 aaggagctac ccaagattga tgaggaaaaa aggcccctgc tactaaggca ataatcggca
     5941 actttgcaga acaaggcatg aaggttgtga ccatgatcgt caaacgacga tcttgctcgt
     6001 tttcaatcgt gcgactggcc atgacgcctg gcactccaca tcctgtagca atcagcatag
     6061 gaatgaagga ttttcctgaa agaccgaatt tcctgaaaag tcgatccatg acaaaagcga
     6121 tcctcgccat atatccgcag tcttccagaa agctcaagca taaaaacaat ataatcaatt
     6181 gcggtagaaa tcctaacact gctcccacgc ctgcgatgat gccgttcaag atcagctcct
     6241 gcatccatcc cgctacttgc cattcagcta acaatctgcc aacatgttct ggtaaccatg
     6301 taccaaacaa tgtgtcattg atccaatctg tccccattgt tcctactgtt tgaatagcca
     6361 gataatagat cagccacatc acaaatgcga agatcggcaa ggctaaccaa cgattcgttg
     6421 caatctgatc gattttgtca ctcatcgata attggaaaga atcatttgac acaacacaga
     6481 gtgtacatag ttgggtaata aattcataac gttcattgac cagaatcgtc tcactatcgt
     6541 cgtccaatag tttctctgtt aactggatca gttgctcgat ctctttttgc tgagaaactg
     6601 ctatctcgta atcctctctt accttctgat ctcgttcaaa atatttcatt gcataccagc
     6661 gtttcttgcc gctttgttct cctagtacat cttcaatttc atgtaaagct gcttctaaac
     6721 gtggatcata tgtacaggga acaggaatag aaggccgctt ttttgcagac tcctgaatct
     6781 tttcgattag tttttcgatt ccttgctttt tcaatacgct gattggtaaa actggtacac
     6841 caagaccata ggaaagcttt tctagattga ttttttttcc ttcttttttg atgacatcca
     6901 tcatattcag accaatgatc ataggaatgt ctaaatccaa taactgcgta gttaaataaa
     6961 gatttcgttc taaattggta gcatcaataa tgttgatgat cagttcaggc tgttcctgaa
     7021 ccaaataatc tcttgcaatc acttcttctg gtgtataagg agacaaagaa tagatgccgg
     7081 gtaggtcctg aatatgaatg ttcggatttt ttttcaacga tccttctttt ttttctactg
     7141 ttacgcccgg ccaattccct acatattgat tcgaaccagt caagagattg aacaagctag
     7201 ttttcccgct gtttggattt ccgactaacg cgatattcat tctttttcct ccctttgtat
     7261 caagattagt tcggcctctg actttcgtaa cgtcagttca taccctcgca ctgtcagttc
     7321 gattggatct cccagagggg ctagttttcg gataactatt tttacatttc gcgtcaatcc
     7381 catatccatt aaccgtcgct tcactgcgcc ttgtccgtgg attgctacga cgatcccagt
     7441 ctctcctgct tttaattgat caagagaagt ccagctttca gaggaagcag tctttttatt
     7501 gacaaagatt tgacctagta tttcccgact tactgccact cgatgacttt ttaccagtaa
     7561 aatggcattg ttgcctgata aattgacgac gacgatttta cttccggcaa cgatcccgat
     7621 attttgcaaa tggcgttttg ttttttcttc tgtttcgatt cgttcgactt gataaacgaa
     7681 attctgcttt gcctgcgcta aggtctgcat attgattcct ctcttgtgaa ataaatcatg
     7741 tattaaaatc attcattata tgttctaatt ttcttacgtg ttacgcaaat aaatgagaat
     7801 cattctcaca tagaatactc tcggtaattg agaatgtcaa ttatacttgt gatattatga
     7861 gcgaatcttt agtattgata gataaaaatg agaaaaaaat atttcttcat agttttccac
     7921 aattttttct ctattaaatt tgctattttc ccacacgata cttgttttca gctctttttt
     7981 caaaaacaca aaacttagta ttccacagtt tccacaacac aatatgtagt gtttgttgtt
     8041 tgactttttt actaagagtt ttatactatc tattatagat aataagaatg tgttagagga
     8101 ggcactcacc atgaacgtaa aaatcttttc taaaaataat tgtatgcaat gtaagatggt
     8161 caaacggttt ttaacagaaa atcaaattgc ttttgaagaa gtcaatatcg atgaacagcc
     8221 tgaagcagta gactggttga aagcacaagg attccaaagt gttcctgtca ttacttctga
     8281 tgcagaaaca gttatcggat tccgtcctga tcagttgcgt aaacttgcca gctaacatga
     8341 ctaaaagaat caaaacgtga tacatggatt tgaagggctt gagacagcac cagtttttgt
     8401 cgcaaacttc caaatccttt tttaaagctt aaaaacaatg caatgatttg caatcaagca
     8461 tcatcaaata cgaaatgaag gttgggcgta cgtatgagtc ttaaaaattt acaagatgtc
     8521 agttatttca agctgaataa tgaaatcaat cggccagtca atggtcaaat ccctttgaat
     8581 aaggataaag aagctttagt tgcctttttt gaggaaaatg tcaaaccaaa tacgatgact
     8641 tttccatcta ttatggaaaa aatcaattac ttgatcgatc aagaatatat agaagcagaa
     8701 ttcattcaat tgtattcacc atcatttatt gaaaagctat atcaattttt ggacgagcaa
     8761 catttttctt tcaaatcttt tatggctgct tacaaatttt attctcaata tgcgttgaaa
     8821 accaacgacg gttccgctta tctggaaact tatgaagatc gagtagcctt caatgcgctt
     8881 tactttgcga acggggatga agaattagca cttgctcttg cagacgaaat gatccatcaa
     8941 cgatatcagc cagctacacc ttctttcttg aatgctggac gtaaacgtcg gggcgaattg
     9001 gtgtcttgtt tcttgactca agtcactgac gatatgaact ctatcgggcg ctcaatcaac
     9061 tctgctttgc aattgtcccg tattggtggc ggcgtaggga ttactttatc aaatcttcgt
     9121 gaagccggcg ctcctatcaa aggatatgag ggtgctgcaa gtggtgtcgt tccagtcatg
     9181 aaattattcg aagatagttt cagctattct aatcaattag gtcagcgtca aggagctggc
     9241 gtggtttatt tgaacgtttt ccatccagac attattgctt tcctttcagc aaaaaaagaa
     9301 aatgcagatg aaaagattcg cgtaaaaact ctttctcttg gcgtgatcgt acctgataaa
     9361 ttttatgaat tgacacgtaa aaacgaagat atgtatttat ttagtccata tagtgtcgaa
     9421 aaagaatatg gtgtcccatt ctcttatgta aatattacag ctgagtatga tcatctagtt
     9481 gcaaatccaa acattcgcaa acaaaaaatc aaagcgcgtg atcttgaaaa tgaaatctca
     9541 aaattacaac aagaatctgg ctatccttac gtaatcaata ttgatacagc gaaccgcgag
     9601 aatccaatcg atggcaagat catcatgagt aatttatgtt cagagatttt acaagttcaa
     9661 acgccttctg tgattaacgg caaacaggaa tatgaagtat taggaacaga tatctcatgt
     9721 aacttaggct cgacaaatat cgtgaatttg atgcaaagcc ctaactttgg tcaatctgtg
     9781 cgtacgatga ctcgtgcatt gacatttatt acagatgcat ctgatatcga tgtcgtacca
     9841 ccgatccaaa acggaaataa gctgaatcat acgattggat taggtgccat gggcttacac
     9901 acttatcttg caaaagaaca aatggaatat ggctcagagg attcattaga ctttacaaat
     9961 atttacttca tgctgttgaa ttattggaca cttgttgaaa gcaacaatat cgctcgtgaa
    10021 agaaaacaag ttttccataa ttttgaaaaa tcagcttatg ctgacggcac ttatttcgaa
    10081 aaatacgtaa ctggagaatt ccagccaaaa tcagaaaaag tcaaagcatt gtttgaaggc
    10141 atttttatcc caactgctga agattggaat gctttgaaac aagcagtaat gaaagatgga
    10201 ctgtatcatc aaaatcgctt ggcagtagca ccaaatggct caatttcata tatcaacgat
    10261 acgagtgcaa gtattcatcc tatcactcgc atgatcgaag aacgccaaga gaagaaaatc
    10321 ggtaaaattt attacccagc gccttatcta tccaatgaga cgattccgta ttacacttct
    10381 gcttatgata tggacatgcg taaagtaatc gatgtttatg caacggcaca acaacacgtc
    10441 gatcaaggca tgagtttgac tttattcatg cgttctgaaa tcccagaagg catttatgaa
    10501 tggaagacaa caacgaagca aacgacacgt gatttgaata ttttaagaca ttacgctttc
    10561 cacaaaggaa tcaaatccat ttattacgta cgtaccttta ctgatgatgc agaagaaatc
    10621 ggaagcaatc aatgtgaaag ctgcgtgatc taatatcata gatagattcg cttattcata
    10681 ttttaattaa aggagcattc tcatgtcaga aacatattat gaagcaataa actggaatga
    10741 aattgaagat atcattgata aatccacttg ggagaagctg acagagcaat tttggctaga
    10801 tacacgtatc ccactttcaa atgacctaga tgattggcgt acattgtctc aattggaaaa
    10861 agatacagta ggacatgtat ttggcggttt gacactgcta gatactgtcc aatctgaaag
    10921 tggcatggat cagttgcgta aagatgtccg cactccccat gaagaagccg ttttgaacaa
    10981 tattcaattc atggaatccg ttcatgccaa aagttattct tctattttta gtacactgaa
    11041 tacgaaaaaa gaaatcgaag aaatttttga ctggacaaat acgaatcctt atctgcaaaa
    11101 aaaagctgag cgtatcaatg aaatctacaa acacggtaca ccgctagaaa agaaaattgc
    11161 cagcgtcttt ttagaaacat tcttgttcta ttcaggtttt tatactcctc tttattattt
    11221 aggaaacaac aaattggcta acgtagcaga gatcatcaaa ctaatcatcc gagatgaatc
    11281 tgtacatgga acctacatcg gttacaaatt ccaattagga ttcaacgagt tacctgaagc
    11341 agaacaagaa acgttaaaag actggatgta caatcttctt tatgagcttt acgaaaacga
    11401 agaacgttat acagaagaat tatacgatcc aatcggctgg acagaagaag tcaagacatt
    11461 cctacgctat aatgccaaca aagcattgat gaacctaggg atggatccac tctttccaga
    11521 tactgccaat gatgtcaacc caatcgtaat gaacgggatt tcaacaggca caagcaacca
    11581 tgacttcttc tcacaagtcg gaaacggcta tttgttaggt catgtagaag cgatgaaaga
    11641 cgacgattat ttgattggat tggaataagg atttatttta attcaaaaat ttttcgaaaa
    11701 ataaaaagag tttagcgtac agatatttta aatgtacact gaactctttt ttatgcttat
    11761 tcacttgttt cttccagcac ttttggactg tctaactttt ccgaaacatg ttccattctt
    11821 ctcaataaat agattttccg gatatttaat attatcgtct taatcactgc atagacaggt
    11881 atgcaaatca gcatgcctaa tattcctgcg acacttcctg ctccaatcaa taccaagatg
    11941 atcgtcaaag gatggatatt cattgatttc ccaaataaca acggcttgat caaatttcca
    12001 tctaattgtt ggatcactaa aatcgacaac gccatataca aagcttgaaa tggagagata
    12061 aacaaaccga caatgattgc tggtaccgct ccaataaaag ggccgacata cgggataata
    12121 ttcgtgattc cgcaaatgac cgcaagcaac aagctataag gctgatcgaa tattctcatt
    12181 gccaaaaagc tcattacacc aataatcaaa gcatctaaga tcgtactgct gatataggca
    12241 gataatgttt cgtttaattc ttttaccgtt tggcgtaact ctttacgaat cgctttcgga
    12301 aagaagtgag acaacgcatc aataaatttg tgcccatcct tgaacataaa tagcaaaata
    12361 aatggaacgg taaataacaa aataaaaaat tgcatcataa atgaaatgat ttttgagaca
    12421 cttgcagata aactgactaa tatgatattg aacaaattac taagagataa atttgctgat
    12481 gctaattgtt cttccaaatt gaaattttta aactcttccc gctgcgccaa ttcatttaac
    12541 catttgcttg tttcatctgc atacattggc aagctctggg tcaattgaat tgtctgttcc
    12601 attaactgag gcactacatt catgacagtt aaaacaacta aaatgattac gaccaaaaac
    12661 gtcaataaaa aaccgaacac tctcgggatc cgatgctttt cgagaaaaac aacgattgga
    12721 tcgaacatat aatagataaa accagcaaca agcaatggta aaaaaattgc cgaaagcatt
    12781 ttcaatattg gactaaaaat attcggcatt tgtaaaataa agtacacgcc gatgatcgtg
    12841 agtactagct ccactgtcca gaaaaataat tttgattgtt taaaacgtga ttgcatacat
    12901 ctcctccaag gtcctttgat acttctattc tatcatttaa caaagagtta cgcgctgaga
    12961 ttttcatttg cttaaaaaaa acaaaaaaaa taaacatatt ttaatgagta gacgagtact
    13021 taaacaaaaa cacggtttgg agtagtgaca aaaattatac tgcagtccct ttttccaaat
    13081 aaacggtgtt caaaagcttg catcttcgta ataagcccag ccaaacgaaa aatataagga
    13141 actattttta tttggctggg cttattactt gatgtaggac atctatttta caacctcaga
    13201 tcatttattg cgcaatactg actaaatgca actttgtgat atttttgtgt acggacaact
    13261 cctcgatcac atcggcataa gtgagccctt ttggaagatc aatcgtatag atatttttgt
    13321 acactcggta gtcatcaacg aattttacgt caaaattcac atcttcgatt acgatatttt
    13381 tctcttcaaa ataatcggta agaaaatctt tggtttcttt tctatggata aattggattt
    13441 ctaacttttt agtcgtaggt acatggatca cgcgtttcac tactgtgagt gcaatagcaa
    13501 tcccgataaa actgatgatc gcaatggaat agtaacccat gccgatggcg atccctaatc
    13561 cagcaattgc ccataaagaa gcggcagtcg taagtcccgt caccgattgt ttcgtgacga
    13621 tgatcgttcc cgcgcctaag aaaccgacac cactcaccac ttgagcaatc agccttgctt
    13681 catctgaacg aatcgttcca gcaagctgtg gatactctaa agcatctctt aatgcaccac
    13741 tagcgatctc aacttggatc aatgcaatga tacatgctcc catacaaact aaaatatgcg
    13801 tacgcatacc tgctggacga tttttatatt gtcgttcaaa accgattgct ccgccaaata
    13861 gcatagcgat ccctaaacgt aaaataatct ctggaattgt caataccata tcattcatct
    13921 aaacaccctc cagtccaata tatcatgtct gaaaggagca gacaaaaaaa gtgcaatttt
    13981 tacctcttac gaaaaaagga ctgtgacaaa atttttgtca tagtcctttt tatgaataaa
    14041 cggtgttcaa tcagctgacc ctcggtatta ctcaacaaac ggcaaaatat ggggagctat
    14101 ttttcctttg tcttctctaa tactcaggtc aaaacgctga tttcacaacc tctttagcct
    14161 actattgaaa attacaactt acttgctgct tcttcatcga tgatcacaac aacattgtcg
    14221 tgattttgca atacacttgc tggcaaatga ttcgttacag gtccttcaat catccctttg
    14281 attgcatcag ctttgctttc gccaaatgcc atcaagacga tttctttact tttcataatt
    14341 gaaccgattc ccattgaaac agcttttgtt ggtacatctt ctgctttatc gaagaatcgt
    14401 ttgtttgcat tgattgttga ttctgttaag tcaactactg aagtcgttcc gtcaaatgaa
    14461 gcaccaggtt cattgaaacc gatatgtcca ttttgcccga ttcctaagat ttggatatcg
    14521 attggatgtg catcgatgat ttgatcatac tttttgcatg ctgcttccag atcttctgct
    14581 tttccatctg gtacaaacgt ttctttgaat ggttttttat caaataattg gacatccatg
    14641 aaatgacggt agctttgttc atctgaaccg cctagtccaa cgtactcatc taagtttaca
    14701 gaagtcattt cactgaaatc caaatcgctt gaagtcattt ctttatataa agtaactggt
    14761 gtgcttcctg ttgccaatcc taatactttt gcacctttgt tcataccttc tttgatgatt
    14821 tcaaatgctt tttttccgcc ttcttcagcg ttttttacac gaatgatttc catagtgatt
    14881 gctcctttat attttggtat agcccaatta tagcattctt tttttctttt tacaataatt
    14941 agtatagacc aaattgcatt tttttcattt tcttgacaat aaataggaat ccgtgttagg
    15001 tttcataaga tggttcaatc aaacaatcca tgttgcatga aaaccaagca agtgattcac
    15061 tgtggacgct ttatgtctgc agttttttta tgaaaaagga gttattatga gtatactgac
    15121 attaaacaac attacccagc aatttggcga caaaatcctc tatgaaggtg tcgatctgca
    15181 attaaatgct ggcgaacatc ttgggctgat tggacaaaac ggagccggta aaagtacatt
    15241 gattaaaatc atcactggtg agatcttacc agatgacgga cagatccatt ggcaaaaaaa
    15301 tattcacaaa ggttacctcg atcaatatgt ggaagtcgat gaaacattaa caatcgaaga
    15361 atttctaaaa actgcgtacg caaaagaata cgaaaaggaa gaaaaaattg cttttcttta
    15421 ccaaacatat agcgagacct tcgatgattc cttgctggaa aaagctggga aactccaaac
    15481 ggaattagac caaggagtgt tttatcaaat cgacacctta gttgctgaga tgagcagcgg
    15541 gttggggatc gatgtcttag gtttagattc actgttgaaa aatctaagtg gtggacaacg
    15601 ttcaaaggtg attttagcaa aactactttt agaaaaccca gatgttctga tcttagatga
    15661 accaaccaat cacttagatg atcagcatat ccaatggctg acgcagtttc ttcaggattt
    15721 tgacggtgcg tatatcgtga tttcccatga ccaagaattt cttgatcaga tcaccaccca
    15781 tatcgcagac atcgagtttg gaaagattac taagtatact ggccatctaa aacaagcatt
    15841 gaaacaaaag gaacaaaatc gcgaaagcta tttgcgccaa tatcatgctc aacaaaaaca
    15901 aatcgaaaag accgaagctt atattcgaaa atacaaagcc ggttcccgat caacgatggc
    15961 aaaaagccga caaaaacaat tagataaaat cgaacggctg acgcctccag cttcagcaag
    16021 taaagctgtc tttgattttc cattctcgcc tattgtcacg acattagcag tggaaacaac
    16081 tgatttagtc atcggatatg atcgaccgct acttgcaccc atcaatttga ccatccgctt
    16141 tggtgaaaat attgccattc gaggcttcaa cgggattgga aaatctactt tattaaaaac
    16201 actgatcggt gagattgaaa aaataagtgg cgatttccac ttcccagata acacaaaaat
    16261 caattacttt tcacaagatc tgtactggga aaatccatta gaaacaccac tacaatattt
    16321 aagcagtcaa tttccaaaag cgactatcaa agaattacgt cgccaactag ctaaagcagg
    16381 gttagttaat caattagcaa gtgaacctct cactacatta agtggtgggg aacaaactaa
    16441 ggtgaaactt gcacagttga caatgaacca aggtaattta ctgattctcg atgaaccgac
    16501 gaaccatatc gatcaagaaa cgaaagaaag cttacaagac gggatacaga aatttccagg
    16561 aacagtaatc atcgtctctc atgaacaaga attttatcaa gatcttgtgc aacgagtcat
    16621 tgagattgaa ccaaaataaa cgtttgattg aatagttgaa aaaaaggagc tgtgacaaaa
    16681 gttttgtcac aactccttct tctgaataaa tggtggccaa ttagctgacc ttcggtatta
    16741 gctcaaaaaa cggcaaaata tgaggagcta tttttatttg gctattctta ttacttgatg
    16801 cagaacagct tttcacaacc tcttttcgtc tattttttat tttcgagatt tctctttcct
    16861 ttaaaaacaa ctgtttgaaa gaagaacgca catccttgaa aaacaagccc gctaaccgtt
    16921 acacctaacc agccatactg ctgccacatt gtcgtcccta gcaatgaacc agccgcacct
    16981 ccaataaagt acataaacat aaataca
//
LOCUS       DAFLVO010000062        16714 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.062, whole genome shotgun sequence.
ACCESSION   DAFLVO010000062 DAFLVO010000000
VERSION     DAFLVO010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16714
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.062"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(251..1462)
                     /locus_tag="L1U99_002130"
     CDS             complement(251..1462)
                     /locus_tag="L1U99_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1212663.1"
                     /translation="MSEVTGYLEQVDNETYRLRAVLGYKPDGSAKRKSKTIKASSKRA
                     AYKELNIWLEQFEGMTDDSLDLFNITFGEFYRKIWLSEAEKNLEPKSYHNYKRMIENR
                     FLDKFDFIPLIDIKPYMIKKIVVNAQRINTKDPGRNSDKPLSRNTKLRMLYAVNNLFL
                     MAKNEYGAIKENPVENVKIPKEKGVKKNIEEPYSEEEIHAMLKAAFEESIEIKTLIVL
                     AFITGARQGEIAALEEKDIDFDKQEIRFHQRISEVDGKSDIRLLPGLKNDDDEKIVTG
                     PAYLFDMLDELIKENKKIRWKLNIKKLKHYFIFDTKQDGTLPRGSYLYKKFKRFTKRH
                     NLRHIRFHDIRHTSATYLLSDPNMTPKELQKRLGHRDFNTTMNVYGHVLRKEKDTATT
                     AFENLLKKDIK"
     gene            complement(1581..2216)
                     /locus_tag="L1U99_002131"
     CDS             complement(1581..2216)
                     /locus_tag="L1U99_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HBN1212664.1"
                     /translation="MAKKVMGQDGKMYKVKKPFYKRVWFWVLIVLLFFGIGGALSGGE
                     NKDSATATSTSTNKETTKETTTKEEKTYKIGDDVAVGKMEYKVNSVEVVKQVGPSVLP
                     TNAKDTFLVVDLSVKNAGDKAVTVDSSFFKLKADGKTFEADSAASMSANQDENGNITN
                     SFFMESLNPDMQQTGKIVFDISEAQANAKNNVLQAQTGYFGTETVSIALHN"
     gene            complement(2352..3005)
                     /locus_tag="L1U99_002132"
     CDS             complement(2352..3005)
                     /locus_tag="L1U99_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212665.1"
                     /translation="MKKVSVMLLLSTALLLSACSNNKKAESTDATSNQETKISKTKET
                     TETSSSTSKSTSKTDSSSTVTSSNQVTAEPSPTVISSSQSTIQTAPQEETYEQMKQRT
                     LQSTPADRANWSNKEWEAFGVALYENGLTTDDAGNIISQDQKEQQAASQQNPEDQQTS
                     AQQDADTLSLTDFVNKYGMSPVAWKVQNGMSEEEALRTTQQKTSGEVQLGFFKYGIQ"
     gene            complement(3108..3314)
                     /locus_tag="L1U99_002133"
     CDS             complement(3108..3314)
                     /locus_tag="L1U99_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HBN1212666.1"
                     /translation="MPSYVVLQVVLKEKFIGKGSQNLSELENTINRQCSKGYRLHTIS
                     TTNGGSKGFGGGDRIQATLVFESL"
     gene            complement(3390..4136)
                     /locus_tag="L1U99_002134"
     CDS             complement(3390..4136)
                     /locus_tag="L1U99_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004564412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1212667.1"
                     /translation="MKQTTQQRLNQLMSERNLKQVDILNMSLPLQKETGIKMSKSHLS
                     QYVNGKSSPDQHKLYLLAKTLNVSEAWLLGYDVPKEDKKNNIPSIETIYNQLEKPRQT
                     KVYNFAEQQLEEQNRGNVVHFPKKEKLPTIKNSASAANPTELVYGDTVVEEEEFERVP
                     NNADFAVPIIGDSMEPVIRNGQFVFVKEQPDVEDGEIAIVEIDGDGVTCKEVYKDYES
                     QTIILRSINELYEDRVVSPEQIRIIGKVVF"
     gene            4296..4520
                     /locus_tag="L1U99_002135"
     CDS             4296..4520
                     /locus_tag="L1U99_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HBN1212668.1"
                     /translation="MSFDYSKLSGRIVEKYGTQYNFSIALGLSERSLSLKLNNRVPWK
                     STELQKAIELLDIPKEEIGEYFFNLEVQNV"
     gene            4544..5305
                     /locus_tag="L1U99_002136"
     CDS             4544..5305
                     /locus_tag="L1U99_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HBN1212669.1"
                     /translation="MNTQKFENNLFELEVKTENGESLFNAETVARSLGFVETKNGKEY
                     VRWRTVNGYLKKYLSQEVAKNDFISEPMVYKLAFKANNVLAEKFQDWLATEVLPQIRK
                     HGMYATDELLNNPDLLIEVATKLKEERTLRLIAEQRVNELQPKADYYDRILNNKGLVT
                     VSTIAKNYGMSAVSFNKLLHELGIQFNQSGTWLLYSKFQDKGYTHIEPFDYEDKNGNR
                     QVKTRMKWTQKGHIFLYETLKKNNYLPMIEREQTA"
     gene            5317..5574
                     /locus_tag="L1U99_002137"
     CDS             5317..5574
                     /locus_tag="L1U99_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212670.1"
                     /translation="MNEEMSQTIKVQKMIDDLTHAIDSQADKIIKELQGQKVWDAKML
                     FKTIKFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
     gene            5666..5917
                     /locus_tag="L1U99_002138"
     CDS             5666..5917
                     /locus_tag="L1U99_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1212671.1"
                     /translation="MEQLALVNLSDLKASLAESEIANEVWDTKQAAEYLKTTTRTLTK
                     DAESGKIPAAKVGREWRFSSIALYQYLKGGKTWVNSTEH"
     gene            5893..6066
                     /locus_tag="L1U99_002139"
     CDS             5893..6066
                     /locus_tag="L1U99_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212672.1"
                     /translation="MGKFNRALVFSAPLIVYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEYRAKKPTEGAD"
     gene            complement(6180..6587)
                     /locus_tag="L1U99_002140"
     CDS             complement(6180..6587)
                     /locus_tag="L1U99_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212673.1"
                     /translation="MSFDNTITISIILALVALISPSITAVINNKHVESMKDKEIELQK
                     HDSKTQTIQTTFSTFLNNVGICIGSNTDKNISAVKASGYAVLPYIQNEDIEVMKIFLS
                     RFGYGNTDAEQKSLETYLIDKVLPILNKSLEKL"
     gene            6748..6972
                     /locus_tag="L1U99_002141"
     CDS             6748..6972
                     /locus_tag="L1U99_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212674.1"
                     /translation="MISVKGLGDEIFEAMMSKAQQDIKEKIISAAAQGQTSCTVRSRG
                     TTPSFLLALEDEGILNIKRRDGSVRLFWQF"
     gene            6982..7176
                     /locus_tag="L1U99_002142"
     CDS             6982..7176
                     /locus_tag="L1U99_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212675.1"
                     /translation="MKDFDSLGARQQPPNEASPVGVDWQENPLYPGDTCYLTEEGYVP
                     VDAILEYVQQHYPKIELGGI"
     gene            7179..8201
                     /locus_tag="L1U99_002143"
     CDS             7179..8201
                     /locus_tag="L1U99_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBN1212676.1"
                     /translation="MANDLTQTTQRSLDEQVISNLGRLQEQGLEMPPGYSPQNALKSA
                     FFELTNNTGGNLLQMAANNQEMKTSISNALLDMVIQGLSPAKKQCYFIKYGNKVQLMR
                     SYFGTMAVLDRVTGGADITPVVVRQGDEFEVAMDGPNMVVKKHETKFENLDNEIIAAY
                     VVIKLTNGKETTTVMTKKQIDQSWAKSKMKDSGPQKEFPEEMAKRTVINRAAKTLINT
                     SNDNDLLVQAAKDTLENEFDNDRKDITPQTEKVATLEQKFFSNKKITEPIQKEPDPIV
                     IPDDIQNEVTRVADVPAHPEIEQAHLIENEDINPIQEELIDIPDFGREEGVEDVSEFE
                     DDEYPF"
     gene            8164..8979
                     /locus_tag="L1U99_002144"
     CDS             8164..8979
                     /locus_tag="L1U99_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HBN1212677.1"
                     /translation="MSQNLKTTSTLSDENYYSNEADWQYMSTSQYKSFLKCEAAALAK
                     LKGDWAPTSDPKALLVGNYVHSYFESKEVHEAFKEENKSKMFSSRKPYGLLKDFQIAE
                     QMIERLKQEEAFMNIYQGEKETIVTGELFGTTWKGKIDCLNVEDEYFVDIKTTKDMHE
                     RKWNENYGSRETFIVNFGYVLQMAIYQELLLQQYGKMFMPIIAAVSKQTPSEAKLITI
                     DQDKMSYELIMLKENIERIVKVKNGEERPIPCGTCEYCRGNLSITGFTSMDDL"
     gene            8997..9779
                     /locus_tag="L1U99_002145"
     CDS             8997..9779
                     /locus_tag="L1U99_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212678.1"
                     /translation="MNLGYIKLYRKVTSSFVWTNSDMFKLWILCLMKASHEDRKFLFN
                     GQEVRLTSGQFVTGAHAIAKEYNEGVPSDKAIAWRTLWRWLKKFENEELLTIQSNARY
                     SVITIINWSDYQSSDKPVTSDGQSSDKPVTTNKNDKNDKNDKNNNPRNSRKTREYADD
                     DPNKKLAILLLKLIRKNRSLKEPDLNKWANTIRLTIEADKRTGKEVQDMIVWATNHDF
                     WSTVISSPTSLRKNFDTMVGQKNKRKQQNISNDELPETGEDW"
     gene            9779..10627
                     /locus_tag="L1U99_002146"
     CDS             9779..10627
                     /locus_tag="L1U99_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1212679.1"
                     /translation="MNKKLSAMAAPYGGLKTADHNCPKCGDPLYIWKTKNKDGTDRCG
                     PTCINKICGYREMVTKNQKEAIQKANEAMKKDAINRMLNSSMITDDAIWTFDFDGYKV
                     VDQETAQIKAMAQEWAKKIVNGSTIHAVITGRTGAGKTHLGAAVIKEVMRASNYKIAC
                     SFISYRELLEQLKFAMNDPEARKAVTGSLMAEIKKSDFVVIDDLGAELGRMEENNQAT
                     PYDVDVLTSLTEARLNKATIFTTNLSSKQLKHAYGERVFSRVMNGTKGNIAVFKTTTD
                     KRRNPV"
     gene            10624..10866
                     /locus_tag="L1U99_002147"
     CDS             10624..10866
                     /locus_tag="L1U99_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212680.1"
                     /translation="MTFVVKKMCYLDSRGRGEASVEFAKHHTTKEEADLVASVCGGEV
                     VEVIKPKRRFSKPKTKPVKKECCCPKSNQAWMRGAK"
     gene            11009..11377
                     /locus_tag="L1U99_002148"
     CDS             11009..11377
                     /locus_tag="L1U99_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBN1212681.1"
                     /translation="MATRSKYGNKKHEVDGITFDSITEAEYYDLALWQAQANGWKVKL
                     QERFELMPKFELEGKKYRKIEYIPDFTFYKSGKLVKVVDVKGMQTKDFKIKAKLFCHQ
                     YQVPLILAKKYRNTFKEERF"
     gene            11392..11553
                     /locus_tag="L1U99_002149"
     CDS             11392..11553
                     /locus_tag="L1U99_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBN1212682.1"
                     /translation="MTTEEVIQMRIRSLRREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            11550..11876
                     /locus_tag="L1U99_002150"
     CDS             11550..11876
                     /locus_tag="L1U99_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212683.1"
                     /translation="MSVDKEAAWRKLMLLIQDENWQEDEAVVAEVQRLGKIANGRIRK
                     KPDKRKQRKGKIVVVLHEGKILMQGTASELSAETGYTRGTIRTYAWRNHTDRKGHEYK
                     YLEEEK"
     gene            11873..12688
                     /locus_tag="L1U99_002151"
     CDS             11873..12688
                     /locus_tag="L1U99_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HBN1212684.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            12827..13138
                     /locus_tag="L1U99_002152"
     CDS             12827..13138
                     /locus_tag="L1U99_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBN1212685.1"
                     /translation="MDELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLEGS
                     K"
     gene            13162..13380
                     /locus_tag="L1U99_002153"
     CDS             13162..13380
                     /locus_tag="L1U99_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212686.1"
                     /translation="MDLYDIESGATLSVESDHLIINFGGKRQIILWVVDDVLFPEIVH
                     DFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            13377..13793
                     /locus_tag="L1U99_002154"
     CDS             13377..13793
                     /locus_tag="L1U99_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HBN1212687.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVIGNIYENSELLEVE"
     gene            13790..14128
                     /locus_tag="L1U99_002155"
     CDS             13790..14128
                     /locus_tag="L1U99_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212688.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDMYGNSESAIKLFGAIEIYADDF
                     PNLWLKEEAE"
     gene            14125..14355
                     /locus_tag="L1U99_002156"
     CDS             14125..14355
                     /locus_tag="L1U99_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212689.1"
                     /translation="MKYEIPLSEADVQSIINGREVNKKLPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSINDTFRLGS"
     gene            14362..14565
                     /locus_tag="L1U99_002157"
     CDS             14362..14565
                     /locus_tag="L1U99_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HBN1212690.1"
                     /translation="MNTRHRRVAKLRKQELNVLKTKFEKEYGISAEETYKVASQCVAD
                     ASDAIRKFGISILSDDRKWEEKE"
     gene            14562..14858
                     /locus_tag="L1U99_002158"
     CDS             14562..14858
                     /locus_tag="L1U99_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212691.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKVKVGDMVRCEA
                     EEFIYPFRGYVEHVYNHSAIIRIENTMECDKWTAKSKENLAVVRLVDMELINDK"
     gene            14935..15348
                     /locus_tag="L1U99_002159"
     CDS             14935..15348
                     /locus_tag="L1U99_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBN1212692.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDALIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            15361..15747
                     /locus_tag="L1U99_002160"
     CDS             15361..15747
                     /locus_tag="L1U99_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212693.1"
                     /translation="MWKDYVSLKELKKDLVFKRIVEWSESELILEDGTKMEVVCSESD
                     CCAWAEGEFKNVKLDAVITDIKIFDKGNRLYNGDGHTSYAEVVVYHNRNEIAKAECTA
                     NDGNGGYYYSVCALKVKDKLCIVTDA"
     gene            16298..16525
                     /locus_tag="L1U99_002161"
     CDS             16298..16525
                     /locus_tag="L1U99_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212694.1"
                     /translation="MRTYWYVSLNNKYPKPMKGQHRRVVMSVQMKAKYSIVEMLREAT
                     PKEIDQYKLVLIGIGWFKDEHIQTNMKRWLR"
     gene            16522..>16714
                     /locus_tag="L1U99_002162"
     CDS             16522..>16714
                     /locus_tag="L1U99_002162"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212695.1"
                     /translation="MKLYYVEKANCWVVEGCLSKYATDIISTQFSELGLKVIFCGEFV
                     SVKEAVLPMTAKSRRSRGSS"
BASE COUNT         5664 a         2726 c         3485 g         4839 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtt
      121 cgttatttaa tggtatttta aatgaagata agcgaattta cagcattttt aaatgcttat
      181 ataccgcaaa ttatcccaag tttttgtata tcctacccga gtttataccc gaaaatataa
      241 ttttttagtg ttattttata tcttttttta ataggttttc aaacgctgta gttgctgtat
      301 ctttttcttt gcgtaagaca tggccataaa cattcattgt agtattaaaa tctcggtgtc
      361 ccaatcgttt ttgaagctct tttggagtca tattaggatc gctaagcaaa taggtagctg
      421 atgtatgtct aatgtcgtga aaacgaatgt gacgcaaatt gtgacgtttg gtgaatcgtt
      481 tgaacttctt atacagataa cttccacgtg gcaaagttcc atcttgtttt gtatcaaata
      541 taaaatagtg ttttaatttc tttatattta atttccaacg aatcttttta ttctctttga
      601 ttaattcatc taacatatca aatagataag caggaccggt tactattttt tcatcatcat
      661 catttttcaa acctggcagc aaccgaatat ctgattttcc atccacttct gaaatccgct
      721 gatgaaatct tatttcttgt ttgtcaaagt caatatcttt ttcttctaaa gctgcaattt
      781 ctccttgtct tgctcctgta ataaatgcta gaacaattaa agttttaatt tctatgcttt
      841 cctcaaatgc tgcttttagc attgcatgaa tttcttcttc cgaataaggt tcttcgatat
      901 tcttttttac gcctttttct tttggtattt ttacattttc cacaggattt tctttaattg
      961 ctccgtactc atttttagcc atcaaaaata agttgttaac ggcgtataac atacgaagct
     1021 ttgtatttct tgataaaggt ttatcagagt ttctcccagg atcttttgta ttgattcttt
     1081 gagcattaac aacaattttc tttatcatgt atggtttgat atcgattaga gggataaaat
     1141 caaatttatc aagaaatcta ttctcgatca ttcgcttata gttatgataa gactttggct
     1201 ctaaattttt ttcggcctct gaaagccata tttttctata aaattcacca aaagttatat
     1261 tgaacaaatc caacgaatca tcggtcattc cttcgaattg ctctaaccag atgttcaatt
     1321 ctttatatgc cgctctttta ctacttgctt ttatagtttt gctttttctt tttgccgagc
     1381 catcaggttt gtatcctaat acagctctta gtctatatgt ttcgttgtct acttgttcta
     1441 agtatcctgt tacttctgac ataattgaat cagctctctt tctctgatac aataggtact
     1501 ataaagaagc ctatcgtata ggtttgtttc tttcttagaa cacgctcgct ttggtcggtg
     1561 gggcgtgttt tttatactaa ttagttgtga agagcaattg aaactgtctc tgttccaaag
     1621 taacctgttt gtgcttgcaa tacattattt tttgcatttg cttgggcttc agagatatca
     1681 aaaactattt taccagtttg ttgcatatca ggatttaagc tttccataaa gaaagagtta
     1741 gtgatattac cattttcatc ttgatttgcc gacatagatg cagccgaatc agcttcgaaa
     1801 gtttttccat ctgcttttaa tttgaagaat gagctatcaa cagtcacagc cttatcacct
     1861 gcatttttta cagataagtc aactactaag aaagtgtctt ttgcgttagt aggaagtaca
     1921 gatgggccaa cttgttttac tacttcaacg gagtttactt tgtattccat tttccctaca
     1981 gcaacgtcat caccgatttt ataagtcttt tcttcttttg ttgtagtttc ttttgtagtt
     2041 tctttattag tacttgttga tgttgcagta gctgaatctt tgttttcacc gccacttaga
     2101 gcaccaccaa taccaaaaaa caaaagtact attaataccc aaaaccatac ccgtttataa
     2161 aacggttttt taaccttata cattttccca tcttgaccca taactttttt tgccatttaa
     2221 atattcctca tttcttgtta taatatattt gtgatctcag aaatgaggta tgagtccgtg
     2281 ttgcagcacg ggctttttta tttataactt ttttagagat tataggcaaa atagtagggc
     2341 ataaaaatat attattgaat tccgtattta aaaaatccta attgaacttc accggaagtc
     2401 ttttgctgtg ttgtacgcaa tgcttcttct tcagacattc cattctgtac tttccatgca
     2461 acaggcgaca tcccgtattt gttaacaaaa tcagtaagtg ataaagtgtc agcgtcttgc
     2521 tgagcgcttg tttgttggtc ttctggattt tgttgagatg ctgcttgttg ttctttctga
     2581 tcttgactga taatattgcc agcatcatct gtagtcaatc cattttcata aagggccacg
     2641 ccgaaagctt cccactcttt gttggaccaa tttgcacgat cagctggagt tgactgtaaa
     2701 gtgcgttgtt tcatctgttc atatgtttct tcttgaggtg cggtttggat tgtactctga
     2761 ctggagctta taactgttgg gctaggttcc gccgtaactt ggttggagct tgtaactgtt
     2821 gaactagaat ctgttttaga tgtagatttg ctagtagatg aactggtttc agttgtttct
     2881 tttgttttac ttatttttgt ttcttggtta gaagtggcat ctgttgattc agctttttta
     2941 ttatttgaac aagctgaaag tagcagagca gtacttaaca acaacataac gctaactttt
     3001 ttcattttat actcctcttt tctttgatac aataagttgt aaagaagcct actataggtt
     3061 taacatccca cgtccacaaa ctttggtcgg tgggcgtgtt tttttgttta tagactttcg
     3121 aaaactaaag tagcttggat tctatcgcca ccaccgaaac ctttactacc accgtttgta
     3181 gtggaaatag tgtgtaatcg ataaccttta gaacactgtc tatttatagt gttttcaagt
     3241 tctgataggt tttgcgaccc ttttcctata aacttttctt ttaatacaac ttgcaataca
     3301 acgtaacttg gcatattctt ttccttcttt ctactatgat aataaatact aacccctagc
     3361 cggagcgcca actacgactg gggtattttt tagaatacga ctttcccgat tattctaatc
     3421 tgttccggtg agacgactct atcttcatat aattcgttta tagagcgtag aataatcgtt
     3481 tgactctcat aatccttata tacttcttta cacgtcacac cgtcaccatc tatttcaacg
     3541 atagcaatct caccgtcttc cacgtctggc tgttccttaa caaatacaaa ttgtccattc
     3601 ctgataactg gttccattga atcgcctata ataggaacag caaaatcagc attgtttgga
     3661 actctttcaa attcttcttc ctctacaact gtatcgccat aaactaattc agtcgggttg
     3721 gcggcagaag ctgaattttt gattgtcgga agtttttcct ttttaggaaa gtgcaccacg
     3781 tttcctcgat tttgctcttc gagttgctgt tcagcaaagt tgtagacttt tgtttgtctt
     3841 ggtttttcta attgattgta gattgtttca atggatggaa tgttattttt cttatcttct
     3901 ttaggaacat cgtaaccaag caaccatgcc tcactcacat ttaaagtttt agccaacaaa
     3961 taaagcttgt gttggtcggg cgatgactta ccattgacat attgcgatag atgacttttt
     4021 gacattttta ttccagtttc tttttgcaaa ggtaaagaca tattcaaaat atcaacttgc
     4081 tttaaatttc tttcagacat taactgatta agtcgttgct gagtcgtttg cttcatctta
     4141 tacctccttt ctgatactta ttatatacct tattgaacat aagttcaata aaaaagttaa
     4201 attaatttga acttttatgt tgacaatgtt ttatgcagga gttatacttt ggttacaaag
     4261 ttcaaaacat ttgaactaga aaggagcgaa ctaatatgag ttttgattat tctaagttgt
     4321 cgggaagaat tgttgagaaa tatggaacgc aatacaattt ttcaatcgct ttaggtttgt
     4381 cggaaagaag tttgtcatta aagttgaata accgagtacc atggaaaagc accgaacttc
     4441 aaaaagccat tgaattgcta gatattccaa aagaagaaat tggcgaatat ttttttaatt
     4501 tagaagttca aaatgtctga acttaagaaa ggaattcgaa aaaatgaaca cacaaaaatt
     4561 tgaaaacaat ctatttgaat tagaagttaa gacggaaaat ggtgaatcgt tatttaatgc
     4621 tgaaacagta gcaagaagtt tgggtttcgt ggaaacaaaa aacggtaaag aatatgttcg
     4681 gtggagaact gtcaatggat atttaaaaaa atacctttcg caagaagttg cgaaaaacga
     4741 ctttatcagt gagccaatgg tttacaaatt agcctttaaa gcaaacaacg tacttgctga
     4801 aaaattccaa gactggttag caacggaagt cctacctcaa atccgaaaac acggcatgta
     4861 cgcaacagat gaactactta acaatccaga cttgctgatt gaagtagcaa ccaaactcaa
     4921 agaagaacgc acgttacgat tgatagctga acaacgagta aatgaattac aaccgaaggc
     4981 agactattac gaccgaatct tgaacaacaa aggattagtt acagttagta cgattgctaa
     5041 gaactacggt atgagcgctg tatcgtttaa taaattgcta catgaattag gtatccagtt
     5101 caatcaaagt ggcacatggc tgctatacag taagttccaa gacaaaggat acacgcatat
     5161 tgagccattt gattatgaag ataaaaacgg caatcggcaa gtaaaaacaa ggatgaaatg
     5221 gacgcaaaaa ggacacatct tcttatatga aacattgaag aagaataatt acttaccgat
     5281 gattgaacgt gaacaaacag cataggaggt aacactatga acgaggaaat gagccaaaca
     5341 atcaaggtac aaaaaatgat agatgatcta acacatgcaa ttgatagcca agccgataaa
     5401 atcatcaagg aattgcaagg acaaaaagtt tgggatgcaa aaatgctttt caagactatc
     5461 aaatttgaaa tgaatccaac aaaaagaaag ctcgccgatg tgttggaaga aaagttggct
     5521 tccgctatca acgagcaaga attactattt gaaaccgata cttttaacag ctgatgtttt
     5581 atagatgaca gtttcatccg aatctatatc attatagatt cgattattgc aatgtacgaa
     5641 ttataaatac aggaggaaat aaccaatgga gcaactagct ttagttaacc tctcagacct
     5701 taaagcttct ttggcagaat ctgagattgc aaatgaagtg tgggatacaa agcaagctgc
     5761 ggaatattta aaaaccacaa cacgcacgct gactaaagat gccgaatctg gaaagattcc
     5821 agcagcgaaa gttggcagag agtggaggtt tagtagtatc gctttgtatc agtatctaaa
     5881 aggaggaaaa acatgggtaa attcaacaga gcactagtgt tcagcgcacc cctaatcgtc
     5941 tatgctttag gactttgggg aagcagacaa gcattaatcg gcacgatcgt ttacatggtt
     6001 tggattttta tggggcttga tgaagctgag tacagagcga aaaagcccac cgagggggct
     6061 gactaaagtg tggttctgtt tattaggtgt ttatctcgtg gccgttttag taaataacta
     6121 catgagaaaa cgtggcgaat actggtatac atcctatgcg gttctagtat gtctaatgct
     6181 tacaattttt ctaatgattt attcaaaata ggtaatactt tgtcaatcaa ataagtttca
     6241 agagattttt gttctgcatc agtgttgccg taaccaaaac ggcttaagaa aattttcata
     6301 acctctatat cttcattttg aatatatggc aggactgcat aacctgatgc ttttacagca
     6361 gatatatttt tatcagtgtt actaccaata caaataccca cattgttgag aaatgttgag
     6421 aaagttgttt gtattgtttg ggtttttgaa tcgtgttttt gtaattcaat ttctttatcc
     6481 ttcatcgatt caacatgctt attatttata accgctgtaa tcgaagggga tataagagct
     6541 actaaagcta ggataatcga aattgtgatc gtgttatcga aactcatttt ttcaccatcc
     6601 agtttttaaa ccattatatc aaaaaggaga gaagaaataa tgcaagaatt agtaattttg
     6661 aaaaataaaa aaagacacga acgccagcaa gcatgatcgt gtccaaaaga aaaatctttt
     6721 aaaccattat aacacaggag gaaataaatg atctcagtta aagggttagg cgatgaaata
     6781 ttcgaagcaa tgatgagcaa agcacaacag gacatcaaag aaaaaatcat ttctgctgca
     6841 gcgcaaggac aaactagctg cactgttcga tcgagaggaa cgacaccaag ttttcttttg
     6901 gcgctagaag atgaaggcat tttgaatatc aaacgaagag atggcagcgt cagattgttt
     6961 tggcaatttt aggaggccgt gatgaaagat tttgattctt taggcgccag acagcaacca
     7021 ccaaatgaag ctagtcctgt tggagttgat tggcaagaaa atccgttata tccaggtgat
     7081 acttgctatc taacagaaga aggctatgta ccagtagacg caattctaga gtacgtccag
     7141 caacattatc caaagattga attaggagga atttaggaat ggcaaatgat ttaacacaaa
     7201 caacacaacg ttcattagat gagcaggtaa tcagtaatct tggacggtta caagaacaag
     7261 gtttagaaat gccaccagga tatagtccac aaaatgcgtt aaaaagtgct tttttcgaac
     7321 tcactaacaa tacaggagga aacttgttgc agatggctgc aaacaatcaa gaaatgaaaa
     7381 cctccatttc taatgcactt ttagacatgg ttattcaagg gttatctcca gcaaaaaaac
     7441 aatgctattt cattaaatac ggaaacaagg ttcagctaat gcgttcatat tttggaacaa
     7501 tggcggtcct tgatcgtgta actggagggg cagatattac gcctgtagtc gttcgacaag
     7561 gtgatgagtt tgaagttgca atggatggac caaacatggt tgtcaaaaag catgaaacaa
     7621 aattcgagaa tttagacaat gaaatcattg cagcctatgt agtcatcaag ttaacaaatg
     7681 gtaaagagac cacaacagtc atgacgaaaa agcaaatcga tcaaagttgg gctaagtcaa
     7741 aaatgaaaga ttctggaccg caaaaggaat ttccagaaga aatggctaaa cggacagtaa
     7801 tcaatcgggc agctaaaaca ttgatcaaca caagcaacga caacgattta ttagttcaag
     7861 ctgcaaaaga tacgttagaa aatgaatttg acaatgatcg gaaagatata acgccacaaa
     7921 cagaaaaagt ggctactctc gaacaaaaat tcttttcaaa caaaaagatt actgaaccaa
     7981 tacaaaaaga accagatccg attgtgattc cagatgatat ccaaaatgaa gtaactcgag
     8041 ttgctgatgt acctgcccat ccagaaatag agcaagcaca tttgatcgaa aatgaggata
     8101 tcaatccaat tcaagaagaa ttgatagata ttccagactt tggacgcgag gaaggtgtag
     8161 aagatgtctc agaatttgaa gacgacgagt accctttctg atgagaatta ttactccaat
     8221 gaagctgact ggcagtacat gtcaacatca caatataagt cctttttaaa atgtgaagcc
     8281 gcagccttag caaagttgaa aggcgattgg gcaccgacgt cggatcccaa agccttactc
     8341 gtaggaaact acgtacattc ttattttgaa tcaaaagaag tacatgaagc gttcaaagaa
     8401 gaaaataaat ccaaaatgtt ttctagtagg aagccgtatg gattgttgaa agatttccaa
     8461 attgctgaac aaatgattga acgacttaag caagaagaag cattcatgaa catttatcaa
     8521 ggtgagaaag aaacgatcgt gactggggaa ctatttggaa cgacatggaa aggcaagatt
     8581 gattgcttga atgttgagga tgagtatttt gttgatatca aaacaaccaa agacatgcat
     8641 gagcggaaat ggaacgaaaa ctacggatca agagaaacgt tcattgtcaa ttttggttac
     8701 gtacttcaaa tggcaatcta tcaagagctt cttttacagc aatacggaaa gatgttcatg
     8761 ccaatcatcg ctgcggtatc gaagcaaacg cctagtgagg cgaagttgat aacgattgat
     8821 caagataaga tgagctacga gctaatcatg ctaaaagaaa atattgaaag aattgtcaaa
     8881 gtgaaaaatg gcgaagaaag gccgatacct tgcggtacgt gcgagtattg tcgaggtaac
     8941 ctttcaatta ctggattcac tagcatggac gatctttaaa aggaggtgct ttgcgaatga
     9001 atctaggata catcaagtta taccgtaaag tgactagttc attcgtttgg accaattccg
     9061 atatgttcaa gctatggata ttgtgtttaa tgaaggctag tcatgaagat agaaaatttt
     9121 tatttaacgg tcaagaagta cgtttgacaa gcggacaatt cgtcacagga gcccatgcaa
     9181 tagcaaaaga gtacaacgaa ggagtcccga gtgacaaagc aattgcatgg cgaacgctat
     9241 ggagatggct taagaaattt gaaaatgaag aattattgac aatccaatcg aacgctagat
     9301 atagcgttat aacaataata aattggtctg actatcaatc gagtgacaag ccagtgacaa
     9361 gcgacggaca atcgagtgac aagccagtga caacaaacaa gaatgataag aatgataaga
     9421 atgataagaa taataatcct cgcaactctc gaaaaacacg agagtatgca gatgacgatc
     9481 caaataaaaa attggccatt cttttattaa aactcattcg aaagaatcgt agtctcaaag
     9541 aacccgattt gaacaaatgg gccaatacga ttcgtttgac gattgaagct gacaaacgaa
     9601 ctggaaaaga agttcaagac atgattgttt gggctactaa ccatgatttt tggtccacag
     9661 tcatttcatc gccaactagc ttaagaaaaa atttcgatac aatggtgggt caaaaaaata
     9721 aaagaaagca acaaaatatt tctaatgatg agttaccaga aacaggtgag gattggtaat
     9781 gaataaaaaa ctaagtgcaa tggctgcacc ttacggcgga ttaaaaacag cagatcataa
     9841 ttgcccgaaa tgtggtgatc cattgtatat ctggaaaaca aaaaataaag atggtactga
     9901 tcgatgcggt cctacatgta tcaataagat ttgtggttat cgagaaatgg taactaaaaa
     9961 tcaaaaagaa gctatccaaa aagcgaatga agcaatgaaa aaggacgcta tcaatcgaat
    10021 gcttaacagt tcaatgatta cagatgatgc catatggacc ttcgattttg atggatacaa
    10081 agtagttgat caggaaacag cacaaataaa agcgatggct caagaatggg ctaaaaaaat
    10141 tgtaaatggt agcacgattc atgcagtgat aaccggtaga acaggagccg gcaaaaccca
    10201 tctaggcgct gcagtgatta aagaagtcat gagggcatct aattataaaa ttgcttgttc
    10261 atttatcagt tatcgagaac ttttagaaca gttgaaattt gcaatgaatg atccagaagc
    10321 aagaaaagcc gtaacaggtt cgctgatggc tgagataaag aaatcagatt tcgtggtaat
    10381 cgacgatttg ggtgcagaac taggaagaat ggaagaaaac aaccaggcaa cgccttatga
    10441 tgttgatgtt ctcacatcgc tcacagaagc tcgtctaaac aaagctacga tattcacaac
    10501 caatttatca tcgaagcaat taaaacacgc gtacggtgag cgagtgttct ctcgtgtaat
    10561 gaatggaacg aaagggaaca tagctgtatt caaaacaacg acagacaaaa ggaggaatcc
    10621 agtttgacct ttgtagtgaa aaaaatgtgc tacttagata gccgagggcg aggagaagct
    10681 agtgtcgagt ttgctaaaca ccacacgact aaagaagagg ctgaccttgt tgcaagtgtt
    10741 tgtggcggcg aagtagtcga agttattaaa cccaaaagac gattttcaaa acctaagaca
    10801 aagccagtga aaaaagagtg ttgttgtccg aaaagtaacc aagcatggat gagaggtgca
    10861 aaatgacttg tttaaaatgc aacgatgaaa cagttatttg gtataagaca ttgcttggat
    10921 ggtcaacttg tgaaccttgt ccaatatgca atgaaaatgg acgacgttcg aaagaacgac
    10981 tcgaaagact aaagaaggag tatagcaaat ggcaacaaga agcaaatacg gaaacaaaaa
    11041 gcacgaagta gacggcatca cttttgattc tatcacggaa gcagagtatt acgatctagc
    11101 cttgtggcaa gcacaggcga atggttggaa agtgaagctc caggaaaggt ttgagctgat
    11161 gccgaagttt gaactagagg gcaagaagta tcgcaagatc gagtatattc ccgacttcac
    11221 attttacaaa agcggcaagc tggtcaaagt cgtagatgtt aaggggatgc agacaaaaga
    11281 ctttaagatc aaggcaaagt tgttctgtca tcaatatcaa gtgccgttga tattagccaa
    11341 aaaatatcgg aatacgttca aggaagagcg tttttaacga ggtggtccat catgacaaca
    11401 gaagaagtga ttcaaatgcg aattcgaagc cttcggcgtg agattgacga tctggaacga
    11461 acaaaggcag tgatggtcaa tgaaacggct agaaaggcaa tcgatttgca catagagaat
    11521 ttaagaaggg aaatccgtag attggaggaa tgagcgtgga taaggaagcg gcttggcgaa
    11581 aattaatgtt gctgattcaa gatgagaact ggcaagaaga tgaagcagtg gttgctgaag
    11641 ttcagcgtct aggaaagatt gctaacggac gtatacgaaa aaagccagac aaaagaaaac
    11701 agcgcaaagg gaaaatcgtc gttgttttac acgaaggcaa aattttgatg caaggaacag
    11761 ctagtgagct gtctgcagaa actggatata cgcgtgggac tattcgaacg tacgcttggc
    11821 gaaatcacac cgatcgaaaa gggcacgaat ataagtattt ggaggaagaa aaatgaacga
    11881 aaacaaatta atcaaattgg gtgtagcagg agcagtaatc gtaggtattg gagttatcgg
    11941 aggatttaag ttcttcgaaa aaatcgataa tggatatgtg ggtgtgcgct attcaatgaa
    12001 cggcggtatc aaagatgaag cactgacgca aggtgtgaaa tttgtaggga ttgacaaagt
    12061 gatccaatat ccaattcgct tgcaaactat ccaatcaaaa aatatttcag tatctacaag
    12121 cgacggcaaa aagacaacga ttgatatcaa atatgactac aaagttgatt caactaaagc
    12181 agcaaaaatg tacaaggaat ttgggaatat cacttcggaa gatatcgaaa gtggatggtt
    12241 aaaatctaag cttcaaaagg tcgctcgtga agtttatgcg aaatatagtc tgcttgatgt
    12301 cctttcagga gattcctcta aagttgaagc tgaggtatta acgaactttg ctaaatcagt
    12361 tgaatctaaa gggtttgaag tcgaagacgt aacacttggt gttccagatg tcgataaaga
    12421 aacacaaaaa tcaatcgatg cgatcattcg agctggtcaa gaaaatgaaa aagcgaagct
    12481 agacgcagaa actgcaaaaa ctcaagctga tagtgaagct tacaagaaaa caaaagctgc
    12541 agaagcagag gcagaatcta atcgcaaagt cgccgaatca gtaacagaca atttgattcg
    12601 ttatgaagaa gctcaagctc gcaaaaagca tggatgggta acagtaaatg gagcagatac
    12661 tgtagttacg gatgaagcag gcaaataata tgggattctt tatggctaaa attctcttgt
    12721 tcttaggttt agtaggagca gcatatctcg tgtatgcgct cctttcccaa actgatgaca
    12781 aagaagatga caacaacgat gaaatgaaat tttaggagga gaaataatgg acgaactaat
    12841 cacaaaagta gagcagtggg ctaaagacaa gggactggat caagcagatc caaaagcaca
    12901 gtttttgaaa gtagctgagg aattcgggga aatagcttcg gcgatggcaa gaagtaatga
    12961 tgaactattt aaagatagcg taggagacgt tatcgtcacg ctgattatcc tttccatgca
    13021 aaaagggaca aacgtacaag agtgtttaga aatggcatac aacgaaatca aaggacgcac
    13081 agggaaaatg gtagatggtg tattcgtgaa gtcgagtgat ttggagggca gcaaatgata
    13141 aaaaagctca ttcaattcag catggattta tatgatatcg aatcaggagc aacactatct
    13201 gtggaatcgg accatctaat cataaatttt ggtggaaagc gccagattat tttgtgggta
    13261 gttgatgatg tactgtttcc agaaattgtt catgatttcg aagaatcaaa agcggttgag
    13321 tttgaaatag tgaaaaaagt aatggaattg attgaaaaat acgaggagga cagcgaatga
    13381 taccgaagtt tagagcgtgg gataaacgaa agaacgtaat gagagatgta gccgtcttgc
    13441 attttactaa aaacggcaaa acaaacttta ttgaatattg gataaatcct accgaattga
    13501 aatcatatca cgtgcgaaac atcgacctca tgcaatccac aggaatgaaa gataagaatg
    13561 gtgtggatat atttgaaggg gatatagtat tagtcagcgt gcgaaatggc ttcgattact
    13621 tagataataa agtttgtatt gtcaaaaatt caatagatta ttccggatta gtttgtgcca
    13681 ctgttgatga agacttagag tatcaaattt ttaacacaga gctgtttgaa gaatacacgt
    13741 atgaagtcat cggaaatata tacgagaata gcgagttatt ggaggtagag tgattatctt
    13801 agctactgac tacatcgatt ctttaaaaga tgaaaatggg aatgtcccag cattgctaaa
    13861 ttgtggaatt aaaagcaaga atagaatcat tttgttacgg atatcggctg atttagcaaa
    13921 atatctttat ctgagcaaga cagcagtata ttacactgcg gctacacgtt atcagtacaa
    13981 gggaaaaaca atcagtcagg attattatga tcgtttaatc agtcctgata tgtatgggaa
    14041 ttcagaatca gcaattaagc tgtttggcgc aatagagata tatgccgatg attttccaaa
    14101 tttatggttg aaggaggaag cggaatgaaa tacgaaatac cactaagtga agcagacgtc
    14161 cagtcaatta ttaacggtcg ggaggttaat aaaaaacttc ctgatggtac tgaattagtc
    14221 atcagacaaa gttatttgaa agatatggca gctccagtat taattgatcg ttttaacgtg
    14281 actgattctg tggtagagaa ccacttgaaa gaatttcgat caagtataaa cgacactttc
    14341 agattaggga gttgattgac aatgaacacc agacaccgca gagtagcaaa actaagaaaa
    14401 caggaactga atgtactaaa gacaaagttt gaaaaagaat atggaatttc agcagaagaa
    14461 acatataaag tggcaagtca gtgtgttgct gatgcaagtg atgctattcg taagtttgga
    14521 atttcgatat taagtgatga tcgtaaatgg gaggaaaaag aatgaaacta aaagacggat
    14581 tttacgctag cagtcacggt atcggcggtt taatgctaga tatgccgaca aagaatccta
    14641 aaacacgtaa gaaaccaaaa gtcaaagtcg gtgacatggt ccgctgtgaa gcagaggagt
    14701 tcatttatcc atttcgtgga tatgtagaac acgtctataa tcactcagcg atcattcgca
    14761 ttgaaaacac gatggaatgt gataaatgga cagctaaaag caaagagaat ttagcagtag
    14821 tgagattggt ggatatggaa ctaatcaatg acaaataaaa aagccggatc gctccgacta
    14881 acataataaa acagacaagt ttattatatc acataaaagg agcagtttga attgatgcaa
    14941 ttgttacgag aggtagattt caaacagaca agatgtaatg cgagagatgt gctgaagaac
    15001 tttcggcgtt tggagcggat ggcaggtcgc tctttgatag atattaagtc gccgattatt
    15061 acggatatgc cgaaggcacc gaagcacggc aataaggcag aggatgcatt gattcagatg
    15121 atggatatag aagcggagag agacgcgatt ttagcggctt tgatggctct tagtctgatt
    15181 agtcgtcaga tactctacta cagtttttgt gtgccagaca gcttctcaaa ctacagaatt
    15241 agccgtgaag tgggttattc agaaagaagt atacaacgga tgaaatcgga agctctaata
    15301 gagtttgcag aagcatataa acacggaaga ataattgctt ataaataggg ggaccatata
    15361 atgtggaaag attatgtatc gttgaaagag ttgaaaaaag atcttgtttt caaaagaatt
    15421 gtagaatggt cagagagtga attaatttta gaagatggaa ccaaaatgga agttgtatgt
    15481 agcgaatcag attgctgcgc atgggccgaa ggtgaattca aaaatgtaaa gcttgatgca
    15541 gtgattacag atataaagat ttttgataaa ggtaaccgtc tctataatgg tgacggacat
    15601 acctcttatg ctgaagtcgt tgtttatcat aatcgtaatg agatcgctaa agcagaatgc
    15661 acagcgaatg atgggaatgg cggctactat tatagtgttt gtgctttaaa ggtcaaagac
    15721 aaactttgta tagtgactga cgcataaaaa aatggcggtt ttttggcgga atgatggcgg
    15781 tttttagcca tttatcagtg atattatggt agtgtcgaaa gattagtgat aggtctgaga
    15841 caaaataata ataaaaggaa catcgtttta ttattgtttc acaattaagc ttcgatagac
    15901 agcaacggaa atattaagaa taaggatgtg aattttaact ccttctaaat tgttcttatt
    15961 atctatcatc cgttgctgtt tattgttaca tacagatcgc ttaggcggtc tttttatttt
    16021 ggccgaaaac ctacattttc gatggccgat tattggagga ggaatagcat gttcaaacta
    16081 tctgaaatca ttaagaagtc cgacgttgag aaattagaga tgttaaaaaa gaagttgaag
    16141 aaatagcagt ctcttcgtga ggctgtttta ttttgctcac aaaaatagac cactatcggg
    16201 taatagtggt caggaattaa atgaaaaaga tgttagggtt gttagctaag tataacatca
    16261 taacgcttac aaaacaatgc aagaaggata aattattatg agaacttact ggtatgtgtc
    16321 attaaacaat aaatatccga agccaatgaa aggacagcat aggcgtgtag tcatgtctgt
    16381 tcaaatgaag gcgaagtatt cgattgtaga aatgctaaga gaagctacac caaaagagat
    16441 tgatcagtat aagttggttc ttattggcat tggttggttt aaggatgaac atattcaaac
    16501 aaacatgaag aggtggttga gatgaagtta tattatgttg aaaaagcaaa ttgttgggtg
    16561 gttgaaggct gtctgtcaaa gtacgctaca gatattatat ctactcaatt ttcagagttg
    16621 ggattgaagg ttatcttttg tggtgagttt gtcagtgtga aagaagcggt attgccaatg
    16681 acagcaaaga gcagacgctc gcgtggttca agtt
//
LOCUS       DAFLVO010000063        16376 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.063, whole genome shotgun sequence.
ACCESSION   DAFLVO010000063 DAFLVO010000000
VERSION     DAFLVO010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.063"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            108..1259
                     /locus_tag="L1U99_002163"
     CDS             108..1259
                     /locus_tag="L1U99_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBN1212696.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVFLLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(1368..3407)
                     /locus_tag="L1U99_002164"
     CDS             complement(1368..3407)
                     /locus_tag="L1U99_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HBN1212697.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDQYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGEKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKDDDDSATKRASELLQYLNQNYQ"
     gene            complement(3465..4022)
                     /locus_tag="L1U99_002165"
                     /pseudo
     CDS             complement(3465..4022)
                     /locus_tag="L1U99_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            complement(4561..4767)
                     /locus_tag="L1U99_002166"
     CDS             complement(4561..4767)
                     /locus_tag="L1U99_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212698.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(4783..5397)
                     /locus_tag="L1U99_002167"
     CDS             complement(4783..5397)
                     /locus_tag="L1U99_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBN1212699.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(5544..6227)
                     /locus_tag="L1U99_002168"
     CDS             complement(5544..6227)
                     /locus_tag="L1U99_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBN1212700.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(6336..6794)
                     /locus_tag="L1U99_002169"
     CDS             complement(6336..6794)
                     /locus_tag="L1U99_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBN1212701.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(6878..8641)
                     /locus_tag="L1U99_002170"
     CDS             complement(6878..8641)
                     /locus_tag="L1U99_002170"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBN1212702.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(8862..10322)
                     /locus_tag="L1U99_002171"
     CDS             complement(8862..10322)
                     /locus_tag="L1U99_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212703.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENYYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(10530..11456)
                     /gene="glsA"
                     /locus_tag="L1U99_002172"
     CDS             complement(10530..11456)
                     /gene="glsA"
                     /locus_tag="L1U99_002172"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBN1212704.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(11479..12906)
                     /locus_tag="L1U99_002173"
     CDS             complement(11479..12906)
                     /locus_tag="L1U99_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1212705.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(12937..14151)
                     /locus_tag="L1U99_002174"
     CDS             complement(12937..14151)
                     /locus_tag="L1U99_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBN1212706.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(14492..14734)
                     /locus_tag="L1U99_002175"
     CDS             complement(14492..14734)
                     /locus_tag="L1U99_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBN1212707.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(14766..15323)
                     /locus_tag="L1U99_002176"
     CDS             complement(14766..15323)
                     /locus_tag="L1U99_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBN1212708.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(15336..15524)
                     /locus_tag="L1U99_002177"
     CDS             complement(15336..15524)
                     /locus_tag="L1U99_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBN1212709.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(15537..16103)
                     /gene="amaP"
                     /locus_tag="L1U99_002178"
     CDS             complement(15537..16103)
                     /gene="amaP"
                     /locus_tag="L1U99_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBN1212710.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         4652 a         3321 c         2767 g         5636 t
ORIGIN      
        1 aaaaatcttt tggattgttg gtttttttgt gagtatattt tcctattttt tcaataatgt
       61 atgttatgct aagttcgggc tatattttat acaaaggaat gatgagaatg gaatttattg
      121 gtattttatg cctgatattg atttcaacaa cgattggctc acatatctcg cggagattag
      181 gtatcccagc agtgattgga caattacttg ttggtgtttt gctaggccaa gctggattga
      241 attgggtcaa acctgatatt ctagtccatg acttttcgga gattggtgtg ttcttattaa
      301 tgtttttagc tggtctggaa agtgatttat ctcttttgaa aaaatatttc cgacctggta
      361 tgttcgttgc tttgcttggg atcatcttcc cggttgtttt tggctggttg acaggcaaag
      421 cattccaagt ttcgggaaat gaagcgattt tctttgggat tattcttgcg gcaacttctg
      481 tcagtatttc agtagaagta ttaaaagaac taaacgtagt gaatacaaaa gaaggatcaa
      541 caattttggg tgcttctgtg gtagatgaca ttttagtcgt tttagttcta agtttcagcc
      601 tatcttttct aacgggggaa gcttctagca atgcttcttt accgcttgtt ttgattgaac
      661 agctaattta ttttgttttt attttcttat tagtcaaatg gattgcgcct ttcctacttt
      721 catttgcaga aaaagtgtac gcaaattctt ctattatcat cgtatcgcta gttatttgtt
      781 taggaatgtc ttacgtagcg gatcttgttg ggcttagctc tgtcattggt gctttttttg
      841 ctgggatagc tgtcagtcag acaaaggtta aagaagaagt ataccacaat gtagaggctt
      901 taggatatgc agtatttata ccagtatttt ttgtcagtgt aggattagaa gttgattttt
      961 ctgactttag tgaacaacta ctctttattt ctatattgac gcttgtagcg attttgacca
     1021 aattgcttgg aggttatttt ggtgctcaga ttgccggttt ttctcaacat agttcattga
     1081 tggtcggtgc tggtatgatt tcgcgtggag aaatggcttt gatcatttta caaattggac
     1141 agcaaagtca attgatcgaa ccacagtact attcaccttt agttatcgtg attttattaa
     1201 gtacacttat ttctccactt gttctcaaat attttacaaa aaaagtttat gaagtgtgag
     1261 taaatcaaaa agaagttgtg aaagagacat cgtgaaaacc gtttatttga aaaaaggact
     1321 gtgacgataa cgccacagtc cttttactgt acttaaaaag caatttttta ttgataattt
     1381 tggttgaggt attgcaatag ttccgatgct cgtttggttg ctgaatcatc atcatcttta
     1441 ttttccaaca tgctgaccat catataacct tggttatcaa gattgaaagc aaacaagaaa
     1501 ctgttctctt gcccctttac atcctgtttt tctttgattt ccgctgtacc agttttcgct
     1561 gccaacggaa tccctaaagc agaaagagaa tgtgctgtac catttacatc ttgcacaact
     1621 tctctcagat ctggcacgat cgtttgtact gctgtttcgc tgatgacatt cttcttatct
     1681 tttgtctctt tatctgcaat caatttagga tagacaagtg tgccattgtt ggtaaaaaca
     1741 gaatacattg ctgcttgctg gataggagta attagaagtt cgccctgtcc atatccagta
     1801 tcagctagca agatatctga gttaaagcta tcttcattag aaatttgtgc tggattcata
     1861 ctaattggca aatcaaggtc ttcaccaaaa atgaatttat ctaagcctgt acgaaatttt
     1921 ttctcaccca ttttcaacgt ttcttgtgcc gcatatatat tatcggaata gatcaaagca
     1981 gtttttaagt ctacttgtga tacatcacta ctgacacgcg ttgttttaaa agatccccaa
     2041 gaactgtctt tttgccattt aagcccgttg atcgtcaaca cttcatttgg atcgatagtg
     2101 ccgttgtcga gaccgattgc tgctgtaatt attttaaacg tagatccagg agcataacct
     2161 gtcgcaaatc ggctgatgaa tggatgttca ggattttctt cataagcttt gtaatcttct
     2221 tgtgagatcc cgtttgtcat tttgtttgga tcatagcttg gagagctagc aagcgcaaga
     2281 agatcaccgg tttttggcgt tgtcgcaaca gttgatccag cttttcctcc tagactgtca
     2341 aaagctgttt tttgtgcctt cgcatcgatt gtcaatttga tatctttgcc attttgaact
     2401 tcatgttcga tcagaacttt tttctctaca ccgtctgcat ctgtaatgct taatttctca
     2461 cctgttgtcc cacgaagatc cttatcaaaa gccatctcca aacctgagcg accgattttt
     2521 ccattactgc ttaattctgg attcttatca atatcttctg ctgtgatatc tcccacgtaa
     2581 ccaatcagct gagcagctgc ttcacccaaa ggataatatc tgccgtctac ttcttgaatg
     2641 gtagctccag ctggaagttc tggcgttgct ccatcaatga ttttcaatgg gacaaagtaa
     2701 tcgggttgta cccagctttg tgaaatcgcc tgattgatag catcttctgt taagtcgaag
     2761 gaggaagcaa tcgctttgat attggctgtt ttttcgcctc catctccaag tttacttgga
     2821 acgactccta attgttttag tttgcctgtt gttgctaatg gttcaccatt tcgatctata
     2881 atattccctc ttgctgcttc ttgtgtggtc aggcttactt tgtcatttcc ttccatttct
     2941 ggaaaaacca agttgggttg ccagttgatc gtggtttgac catcatttct gtctaatgtt
     3001 cctttataag aaagatcttt caattcacct aatgaggtat tcatctttgc tttatatgaa
     3061 aaactgtaag tagaatcgtc ttttttatct acttttagat tcgatatctg aagtcctttg
     3121 acatcagcag caccgtatat attctggtat tgatctaaga tctctttttc agataatgca
     3181 cttttatttg ccgccttttt tgatgtcatt tctgcagctt tgttataatc tcccttgttc
     3241 aaagcttgga caaattgctc aactgtcttt tctccagctt ctactgcttg ggtttcttga
     3301 tagtgctggt agtaaaaata accgccaccc gcagctgcta ttaagatcac tgcgccggca
     3361 atataagcgc ctgttcgatt tttgccgtgc ttgtcacttc ttttcatttt ttcctccttc
     3421 tcttgcttgt cattccttta tttcactatt tatacctgtt tattctaaca tatgtctttg
     3481 aggaaatcca taccacaatc cagaagcaca ctttctggaa ggttcgtttg gatactacca
     3541 agtaatttcc caaccgcttt gggtagcttg aatattgaag ttacgtcttt cagctgctga
     3601 gagatagctt tgatcacttg ctgctgcctt ctgatcctcc cgaagtctcc ttctttgtct
     3661 tcccgaaatc gagcatactg gagtaaagta ttaccatcca tcacttgctc tcctttgttt
     3721 atatatacgc catctaaatc tagagatttt tctgcatcga tcttgactcc accaggaaac
     3781 agttcattaa cgcaatcgat aaaatcttga aatgtgatac ttgcataata gggagcttca
     3841 aatttgaaat tttcctttaa tgtttgattt aataaatcaa ctcccccata agagtaagct
     3901 gcatttatct tattcattcc gtaacctgga atatcgacat atgaatctct catgatagag
     3961 atcagttttg cttgttgtgt tttctggttg tattgtgcaa ccagaagtga atccgagcga
     4021 cctccaccaa tcgatctttt ttcaccgcat ctcctcctca cacagcaatc cacttgtcag
     4081 gtgaggagcg agtttgtctc atcaaataag tcagtcacaa aaatataaag aaaaggtcag
     4141 aaaccttttc gaacaagaat tctgacctag catcatctca tcgtccgagt tttagcacta
     4201 tacaacgtaa agaaaacatt cttagctatt ggaaaaagcc ttaatccaac agtttctgtt
     4261 ttacccattg gcgactttcg acgtttctgg gcaacagcct atgtttgtat aggagcctca
     4321 cctaacaagg ttattactat attctattta cgagttcatg atagactttt cctaatgatt
     4381 aggcaatgga atttgaaatg aaatagtgaa atttaacaat ctttaatatt ttttagaaaa
     4441 aaataacaaa taagttgaaa gaatcccgtt gcaaattctt tcagttgcac caggattctt
     4501 tgataatttt ttagttttat gtgttttttt atatgttttt tcacttttcg gaataaatat
     4561 ttatttgtta aagtaattaa acaatccgct aatcgtttga tctggcattt ctatttcctt
     4621 accatctaaa gtaacagtag taacgacaaa atggtcttgc aatggcggaa cttctaagta
     4681 ctgcccttgc agaaaatcat tcactgtttc atattctttt ttcatttctt ttgaatctgt
     4741 cgatggttta tagcttattt ttaacataac tagtgctcct ttttattcgg gacgtgcaat
     4801 cgtgaaaatt tctcctattg ctgcataatc atttcctgcc aaacggctta cagcattcaa
     4861 ttttcttgga tcgatccttc ctgtcttatc atcatagact gtttcattta aatgatattt
     4921 ctgtacttct agcaaaaata aatcagctgt tactttattt ttattccgta tctcgacatg
     4981 ttcatataag gatgtttcaa aacgaacttt tgcttctgtc aatgctggta ctgaaatgat
     5041 tactgaatca gttaaagtca agtcagtcag gtacagttcg ctttcctcat taggcagatt
     5101 ggctgctgtt ttatttactt cttctacgtt gtcctcatca aggatatgga taacagcttc
     5161 tcttgtctca agaatattct ttgctgtgtc ttttactgca tcttgttttc tctggatcgc
     5221 caaggataag atgggtcgat tcgaactgac gatattgaag taactgaagg gtgcgatatt
     5281 cactatatct tttgctgatt tagtcgttac tactgctact ggtctaggga tgactgaacc
     5341 aatcagcaac ttgtaatttt cacgttctgt caattctgaa ggactccgtt caaacatggt
     5401 ttcgccttct ttctataaaa ttcgttaaaa agcagatctt gaagacaaaa tgaaaagtaa
     5461 tgcttttttc atcttcttag aatctgcttt aaactatcta tcaatttttc ttttttgtca
     5521 agaatctgtg ccgtgcgtgt tttttagtta tttgctttac ttgcggcttc gacatatctt
     5581 ttagtgatca attgcggacg ggtgataata gatccaacta cgactgaaaa agcacctaat
     5641 tcatatgctt tctctacttg ttcaggagag tcagtatgtc cttccataat tactgggata
     5701 tcgacttgtt ctatgatttg attcaataaa tcaaaatcag gtgtctgcgt ctttcgtgaa
     5761 tattctgtat agcctgctaa agtcgtagac aaaagatcaa aaccatcttc ttgcgcttga
     5821 agcgcttcct caaaagtcga aatatctgcc atagctaacc gaccgtgttc gtgaatcatt
     5881 tggacaagtt cagcagttgt tttttctgtc ggacgtttac gagaagttgc atccagtgca
     5941 atgatttctg cttgcgtctc caaaagttct tccacttctt tttctgtcgc agtaataaac
     6001 acttctgacc catcgtaatc tcttttgata atccctatta ccggtaaatc aacgattcgc
     6061 ttgatttcat tgatatcttc tgtcgtattt gctcgaatac caactgctcc gccttctttt
     6121 gcagccaaag ccattctccc cataataaaa gaactgtgta gcggctcgtt ttccaaagct
     6181 tgacaagaaa cgacgactcc gcctttgatt tgttccagtg tatccacaat atctcctcca
     6241 gtaatgttat ataaaaatac agcttcatat aaaaatgtaa cccttttcta ttcaggagac
     6301 aataatgagc tatttctttc agcagacctt tcttactaaa agaaaattac ttcaaattct
     6361 tcgtatacga ccagcttctc ttctgtaaat tctatgttca acgcttcttt ataagcatgt
     6421 ttaaaaaact cagcatggac tttccgccaa taagctaatg tccgatcccc ttctccttct
     6481 ttccaagcat gctctttcgt gacttcacta aaaggcaaga tggtcacatt tatatttttg
     6541 atgatacaaa ctggttcatt ttttccattc aggaccacgt ctaattgacc aacttttggt
     6601 aaaggctcat tctcttgttt atacagatcg taaccacttg atgtaccagt ctttatcttt
     6661 tttacaacta gttcgctcaa ctcgtctgcc attttttctg tatccccaaa tgaaaagaaa
     6721 cctaattttt ctgattgata actaggatat ttttcttgga actttttgac atattcttct
     6781 acttgctgat acataacatc cacccctttg ctttttataa tgaaaaaacc atccagatac
     6841 tagtataaac aattatctgg atggtgagca taatgaatta ttgaatattc aagacacgca
     6901 gactatcttc aacgatttgt tttggtgtta aatgataacg ttcataaagc tgccctacag
     6961 gaacgctatc cgtgaattct ttctctgcac caaaatttaa tacgttcatt gaagaatcac
     7021 cataataacg actgatattt tcgccaaatc ctcctgacaa actaccatct tctaatgtga
     7081 tgactaattc gtgtgtttct tttaatttat ctaatgtttc tacgtcattt tctgtgatcg
     7141 ttcctggatt gatcaacgtt gcttcgattc ctttttttct aaaagctttt actgtttctt
     7201 ttcctaattc aagaaaaccg cctaaagcta aaattgctac ttttcctcca ttatttactg
     7261 tttgataggc tggaatacta taatcatttg cgatagctgt accatgttct acaccatgtg
     7321 taggaattcg gattgctaca ggctgcgctg tttgttcgaa cgcccaatct agcatagaga
     7381 tcatatcctc ttttgttgct ggagcaagat atttgatgtt cgggatactt gataagtaag
     7441 gaatgtcaaa tgttccttgg tgtgttcggt cactagctga gatcgttccg ccaccgacta
     7501 aaataatcac tggattctcg ttgatcgcta aatcatgtga taattgatca tatgcccgtt
     7561 gcaagaaagt acttgattgg aagacgactg gacgtactcc ctgagaagcc aaagcagaag
     7621 cgaaagtgat agagtgctgt tcagcgatcc ccacgtcaaa ataatgatct ggatgttttt
     7681 cttggaatgt tttcagtcca aaggcgcctg gtatcgctgc attgactgcg gcaataggag
     7741 ctgtacttgt ttgcattttc ttatccaaat aatccatgat gatcatatta aatgtttctc
     7801 cagaagttac ttgctttgcc tccccggtgg acagatcaaa tggtacatgc caatgatatt
     7861 tcattttatt atcgattgcc ggctgataac cgcgaccttt ttccgtatgg acgtgaagta
     7921 caatcggatg atcaatatct tttacttctt caaataaacg gatcaccgtt tccagatcgt
     7981 ttccattatc cacgtaacga taatcaaatc ccattgcttt aaataggtta ttgctgcttt
     8041 taccgttggt ttgacgaagc tcagctaagt ttttatataa actgccatga ttctcatcaa
     8101 tagacatctc attatcgttt actaatacga ttagattgga ttgtaaaaca ccaccattgt
     8161 tcaatccttc aaaagctaag ccaccactta gggagccgtc accgataaat gctaccacat
     8221 ttcctgattc tttcttcaga tctctcgctt tagctaaacc tgttgctaag ctgatagatg
     8281 tagatgtgtg ccccactgta aaatagtcat gtttactttc atgttggttg gaatatccgc
     8341 tcacttcacg gtaatgtcct ttttcaaaac cattttttcg accagttaaa agcttatgac
     8401 cataagactg atgggaaaca tcccaaacga ttttatcctt tggtgaatca aatacataat
     8461 gaaacgcaat cgttaattct actacaccta gattcggacc aacgtgccca cctacatcgc
     8521 tgtccttttg caagattttt tggcgcatct cttctgccaa ctgtttcatt tcctcaacag
     8581 ataatttttt gacatctgcg gggctattga ttgcatccaa tacatgtaat actgtactca
     8641 taatacattc tctcctccgt actatcttct tttaatgaaa atagatttgt tacactttat
     8701 ctattctact acttagagtt gactctaagt caatagcatt ttaaaaaaat ttcagagaaa
     8761 gcttgttata taagtagatc ttcgcacgaa tcaggactca aataaaaacc ttctacagac
     8821 aattaaaaag ctttgtagaa ggtctcctaa ttaaggtctc atcaagaaat atgttttttt
     8881 aataggtgaa gttcctgagc aatatgatac aaatggatgt ttgcaccttt taatgagatt
     8941 ggatagatct ttgtcttttc agtttctaat ccattttgat agctagcagc atcgcacaaa
     9001 accactcttt ttttcgcaca tagacattca tcaggcaatt cttctaatga acgaaataaa
     9061 ataggattta tttcagcgat gccttcttcc gcatacaaat gaaattgggt tcgataaaaa
     9121 aattgtttga ctgaactttc tgaaacaaca aaaatttcta tttcctgtct ccccgcttgt
     9181 tcactgttga tcaaagaaag acttttgacg aattttcgaa tgaaattttc attccatctt
     9241 agttggattt gatttttctt tttccactct tccaatattt ctacaatttt tccgtacaga
     9301 agttgttctt tttctgatag aagatagatc ctttccggta aaaatacttg tccatctgcc
     9361 cacaacgtac ggacaaattg taaaaaggat tgcttgaaaa taaaattttc tgcatcgtcg
     9421 atttcagcga tactaataat ctgtaaaatc aattcattca gtgataggtc attgagaaca
     9481 aaatttttat aaacaacttc gaaatctttt cttaacagct ccatgttctc attggtataa
     9541 tttctactgt tgaacaaaga aaaaatataa tagacatctt cttcttgtaa gtctagaatt
     9601 cctttttgct cttccaatcc ttgacagact aattgaaata acggcttcgt ttctgcgctt
     9661 ttcttatctt cttctttcag tccaagggga aatgcctttc ttccgattgc gatctctatt
     9721 cctcgtatga taaaggactt ttcatcttcc gaatatcttc ttttaaaaaa atgagtctct
     9781 acataatcaa tcaactcgtt acaagcttct tctacatacg gatttttatt ttcatagcct
     9841 tcccaattga cataacgtac taaagctagc aagatgttcc gcgagtcaaa ttctgggata
     9901 atgatttctt tatttttcaa ataataattt tctttaaaaa aatccaatac gatttttttg
     9961 attgtatata ctttgctcaa agaaataaat tcaagatcag ccagttctgt actcgtgaat
    10021 ataccattaa aataataact taaaaacttt aaaaaataag attgaccgta cagaaactgt
    10081 gtgagctcag aaagagcaat accatgtttg aatacgagtt tatacttatg cttctctctt
    10141 acttgttctt ttatacaata ttctagacac tcggctagac tttctagatc gtgaaggatc
    10201 gttggtgtag tcacccttag agaaatagct gtttgttcga tgtctatttc ttggaattca
    10261 aataattgtt cacacagata cacttttcta aatatatttc gctcgatgta attttccagc
    10321 attcctgata cacgcctcca gtttttctta tgattttatt taatcatatc tgtaaatcgt
    10381 atttttgttt cctttttatt tagaaaagcc ctttcaaaaa ccaataaaaa aagaaactgg
    10441 gacaaaagtc aaacaagctc acaatttcag cctcattgta ggtagctttg agccgtttgg
    10501 acttttaccc cagcctcttt caagaatggt tattcaaaga tgtcagcgtc tagttctttg
    10561 actacatctt tcaacaattg gataccagct gcgctgttac caaatggatc tagtgccggg
    10621 ctgaagacac ctatgccgta acgatttggc acagctgcca tcaacccgcc gcctacaccg
    10681 ctttttgcag gtacaccaac atggacggaa aactctcctg attcatcata caaaccagca
    10741 gttgtcataa ttgatttgac gattgtagca ctttcttcag taatgatttg tttgccattc
    10801 caaggagcaa ttcctttatt tgccagcaca gcagctaatt ttgctatgcc tgtagcggtg
    10861 acattgaggg agcattgtct gaaataagca tcgagtatct ccggtacgtc tccttcgatc
    10921 atttgattac ctttcatata gtaagcaaga gagcgattga tatcacctgt tcttgattca
    10981 gaatgataga tttcttcatt caatgtgata ttaggatcat cacagatctc tttcataaat
    11041 gacaagattc gctcaaattt ttcatctgca tctttaccgg caatcaacga ggttgttgca
    11101 atcgctcctg cattaacaaa aggattcatt ggatgtttgc gatgattgat ttccatattc
    11161 atgatagaat tgaaggcaaa accggttggt tccgtgttga ttgtttgaaa gactttttct
    11221 attccgttgt ctttgattgc taataacaat acgggaactt ttgacatgct ttcgatggca
    11281 aagcgcacat cggcgtctcc tccctcaatc agttgttttg tatccaaatc ataaatcgcc
    11341 atacctaatt gtttgggatc cacttcagct aatgctggaa tgtaatccgc cacttgtcct
    11401 gtttgataat agtggaaatt ttttccaatc aattgttcta attcttttac ttccatttga
    11461 ataaccagct ttcatttttt atttttctgc atgctggaat ttatgacggc atgcgtagat
    11521 cgtaaatgga ataactaaga cgataagata agaaacaatc agaatcgttt cataaatccc
    11581 atgctgtcca gctgcgatac tagcaggtgg aacaaatgag atacaaaaag caaaaagtga
    11641 agtcaaaaga cctaaacaag caacgattac ttttacaact tttccgcctg gaacctgata
    11701 ggctctttca agactgtcat ctttaaaaac cagcttcaaa tagcccgcga aaaacataaa
    11761 gtacaacatc aggtagatta caacagtcaa tgacatcgct gcaagaaatg aaagattatt
    11821 ccccccgccg cttaatgtaa agacggctgc ccagattgtt gcaacgatcc catttgcgat
    11881 catcaaatga gcaggaacac cgtgtgtgtt ttcttttgca aaatattcag gaagtaatcc
    11941 ttcttctgct gctacgtgaa gtgcttttga aggagaggtt acccaagaag caatttctcc
    12001 gatgacacct aaacaaacaa gaatcgcaag aattttcgca atccatgcaa gatttggatc
    12061 aatgtgtctt aataggaatt ctaacgattg aatcacccct gtattaagag acaaaccatg
    12121 ttgaggtact gtagtagcga cggtcaatcc gccaaaagta tctaaaatga ttgccagaat
    12181 aaccaataca aacattgcta atggataatc ctttttaggg ttttccattt catttgcatg
    12241 actggcagat gtttctacgc ccatatatgc taaaataaag gaaacaaaaa caaccagcgt
    12301 aggcaatttc gaaaaatcag gaatcaatgt tttcatagac agtatcgttt gtagtggagc
    12361 gcctgaagcg acataatgga tccctaagcc aaacaagact aatgctggca acaagatacc
    12421 agctacaaaa ccgatccgag caatcaatga agtgtatttg gttcctttta actgtgagag
    12481 taaaatagcc cagaaaataa tcaataggat tgccaatttc agatatttat tgttttgtat
    12541 agcaccaata cccgttgcat aggataatgc accagttaag aaatacagca tggtcaagta
    12601 gccaactgtt atctcaaacc attggaaaaa gattgcggca aaaccgaatc gttttcccaa
    12661 tgtgcgactg acccaagtat agacaccgcc tttttcccat cctttcaccg ttgccatctc
    12721 tgctgcgcac aatgccacag ggataaacca tagcaaaccg cctaataaca agaaaaatac
    12781 taagctgaag cctgaggtcg cgaatgtggg atattcatat aatgaaacga ccattgagat
    12841 ggtcatagcc aaaaagccaa agaacgttaa tttttttgca ggaattttcg ttttgctttg
    12901 ttgcatgaat cttcctcttt tctatttgaa tttgtttcaa ttgagtttgt tgccaaagaa
    12961 gaaaaagtcc aatccttctt cttgttcttc ttttgtagta gtgatcgttg taaagtgcat
    13021 cgccgatttt aaaatcactg ttgtcagcac ataggcatac acggcagtaa tgatgacacc
    13081 aatcacttga atccctaaga agtaccagct gcttggattc gttagtaaat ggctgttaga
    13141 tgcaaagatc cctatcagaa tcgtacctgt gaatccgccc atgccatgaa caccccacac
    13201 atcaagtgca tcatcccatt gtttcttttt acgaaaatca acagcagcat gacagacgat
    13261 acccgcaatg atcccaatca gcatggcact ttttgcttct acataaccgg cacaaggcgt
    13321 aatggctgcc aatccagcaa cggatcctgt tagtacgtcg acaaaatcaa agccatttcc
    13381 ttttactttt gcaatgatca gccaagtaat catcgcaaat gcaagagcga tgaatgttga
    13441 accaaatgca ttgactgctt gttcatctgc tcgaagtgca ccaccggaat taaaaccgaa
    13501 ccagccaaac caaagcagtc ctgtaccgat agcagctgcc ataagactgc tatgctgact
    13561 tctttctcct aaaggaatct ttctttgacc aagtgtgagg atacatgcta aagagccgaa
    13621 tccagctgtc gtgtggatga ctgctccacc agcgaaatct ctaaatccca tctgatccaa
    13681 aaatccgcca ccccatatcc agtggcaaac agggaaataa atcagcagat tccaaaaaat
    13741 aacaagtata atatagcctt ttaaattcaa tctccctgca aaagctcctg tcatcaaagg
    13801 aacggtaatc acgataaaca tcagttggta aagaaagaac attaaaaatg gaatcgttgc
    13861 accatgaaac atgttgggga agcttgtaac atgtctcatc aaaaagaaat ctgccgggtt
    13921 tccaataaca ccgccgatat cccgtccaaa ggccaatccg aatccaccaa atacccacat
    13981 aatcgttgtt atcccaacgg agagaaaaga ttgagacatg atcgttagta tattattctt
    14041 ccgtgctaat ccgccgtaaa aaaaagctag accaggagtc atcaggcaaa ccattgctgt
    14101 acataaaatc atgaatgctg tatctcctgt attgataggt aatgtattca tttttttcgc
    14161 ctcctttcta cgattacgag tataaaagaa ggtgtagttg tttttttctt ctgttttttt
    14221 gaattaatac ttgcatttat aaaagacaga caattaataa aagcttgatg tgttgtgctc
    14281 tttttcgttt ttcacacaaa taaagacaaa aaataaacgg tcttcttttt atagaaaacc
    14341 gtttattttc gtcttttttt atttttaaag atattttttc ataaggaata aagaatactt
    14401 catataaaat atataaaaaa gaaccgcagc gagtgtcgct acggttctca aatttgttct
    14461 tcatttcaac ataagttttt cttcaatttg cttataattt acgtgcaaag aatgaaacga
    14521 ctaatactaa aatgattgca ccgatcaatg atggaatgat agccattcct gcaattgttg
    14581 gtccccaagt tcctagtaaa gcttgtccaa ttgctgaacc tactaaacca gcaatgatgt
    14641 ttgcgatgat ccccattgat gatcctttat tcgtgattgc tcctgcaatt gctccaatga
    14701 taccgccgac gattaatgcc caaataaatc ccattttaaa ttcctcctaa ctgacttctt
    14761 acttcttatt gtacacgtgg ttcgttattt tctttgactt tttgtgcacc tttgcctaca
    14821 gcagattttg ctttatctgt ttggcgtgaa gcaaattgtc ctgtggattt tgctgcttct
    14881 gttactttgt cttgtactgt ttcttgatct ttttggtatt cttcttgtgt tttgatgtct
    14941 gcaacattca cattcacttc gataacatct aaatgtgtca tattgtttac ttcagtactg
    15001 atcaattctt tgatttggtt gtaaatatct tcgatgtctt taccgtattc tacgatcaca
    15061 tctagatcca cagctacttg tttcttacct acttctgtat tgatacctgc tgttacgtta
    15121 tctgtgttga ctaatttttc agccatattt gagaaaaatc cgccatctaa tgtcaataga
    15181 ccatctacat ctttcaatgc ataaccgatg attttttgga tgactttgtc ttcataagtc
    15241 aattcaccat tcatcatgcg gttttctcct ttttcatttg ccaaaactga tccatttgtt
    15301 gtattcatgt ttttgttttc catctttgtt tcctcctatg atttaaaaaa ttgatcaact
    15361 attcctgact gtttcaaata aaaaccgatt cctgcgccaa ttgctgtcat gattatgatc
    15421 aacaatgtct tgaaaaatcc aatcgttaac cataaaacag ctagcagtag tccaagaccc
    15481 ccaaagataa tagggagctt gtatgctgaa aatagttctt tcattatttg gccctcctat
    15541 tccactcgag agtgcttgta gtctcttgta tcttcttgtt cttcataacc gctgtatgtg
    15601 actgccactt tgaccgtttc ttttgttccg agtactttag ttacttcttc ttcgatatct
    15661 tgcatcaata cacctgtttt ccctactaat gaagaagttc gtttcaagtc tccgttgaca
    15721 tggatatgga ttcgattttt cgttgaacgt atccgtactt taggtgaatg aatgaactct
    15781 tcttcgtgta aatgggaacg taccaaccct tcgatcgctt ttttgtcgat tgttagtttg
    15841 ccatcttccc gtttcataac gaaagttcct cttgactttg gatagaaaag aacgactagc
    15901 aagatgataa tagcaagaac ggcaaatact acagctgccc agaaaatata ttgttgcatg
    15961 tagtaattcg ttaaagtaaa gaagcgaaat cgttccaatt gttcaggcat aatatacggc
    16021 gcattgatca acgcaatcgc tagaaatact gaaagtagca gtaaactcat gataacaccg
    16081 attattttta accccttatt cattttccac ctcctataaa cttattttta ccctgtaaat
    16141 aactctaccg acaatcacag tatagatagc gaacagttag catagcatca gtaaataaag
    16201 cgctaccaaa cattgctgga tcataacggc gttttattgc cagtctgata ctgaaataac
    16261 aattgcttac ttattctcta tttacttttg attgctggct atacttaaag gatattattc
    16321 aagattaaaa attgcaaaga ttatgctcag ttattattac aagattctat ttattt
//
LOCUS       DAFLVO010000064        16220 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.064, whole genome shotgun sequence.
ACCESSION   DAFLVO010000064 DAFLVO010000000
VERSION     DAFLVO010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.064"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..477
                     /gene="scm"
                     /locus_tag="L1U99_002179"
     CDS             <1..477
                     /gene="scm"
                     /locus_tag="L1U99_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBN1212711.1"
                     /translation="STDTSASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSSDSST
                     TTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNR
                     TNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
     gene            complement(632..1618)
                     /locus_tag="L1U99_002180"
     CDS             complement(632..1618)
                     /locus_tag="L1U99_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBN1212712.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1641..2207)
                     /locus_tag="L1U99_002181"
     CDS             complement(1641..2207)
                     /locus_tag="L1U99_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBN1212713.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2221..2637)
                     /locus_tag="L1U99_002182"
     CDS             complement(2221..2637)
                     /locus_tag="L1U99_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBN1212714.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3094..5028)
                     /locus_tag="L1U99_002183"
     CDS             complement(3094..5028)
                     /locus_tag="L1U99_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBN1212715.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5309..6265
                     /locus_tag="L1U99_002184"
     CDS             5309..6265
                     /locus_tag="L1U99_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBN1212716.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6355..7458
                     /locus_tag="L1U99_002185"
     CDS             6355..7458
                     /locus_tag="L1U99_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBN1212717.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7471..8424
                     /gene="menA"
                     /locus_tag="L1U99_002186"
     CDS             7471..8424
                     /gene="menA"
                     /locus_tag="L1U99_002186"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HBN1212718.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9238..10584)
                     /gene="gor"
                     /locus_tag="L1U99_002187"
     CDS             complement(9238..10584)
                     /gene="gor"
                     /locus_tag="L1U99_002187"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HBN1212719.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10718..11971)
                     /locus_tag="L1U99_002188"
     CDS             complement(10718..11971)
                     /locus_tag="L1U99_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBN1212720.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(11977..12900)
                     /locus_tag="L1U99_002189"
     CDS             complement(11977..12900)
                     /locus_tag="L1U99_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBN1212721.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13121..15613)
                     /locus_tag="L1U99_002190"
     CDS             complement(13121..15613)
                     /locus_tag="L1U99_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBN1212722.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15620..16087)
                     /locus_tag="L1U99_002191"
     CDS             complement(15620..16087)
                     /locus_tag="L1U99_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBN1212723.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
BASE COUNT         4765 a         3394 c         2887 g         5174 t
ORIGIN      
        1 agcacggaca cgtcagcttc aagcgacagt acggatacat ctaccacaac aagtgatagc
       61 acggacacgt cagcttcaag tgacagtaca gatactacct ctaccacaag tgatagctca
      121 gattcatcta ccactacaag tgatagcacg gacacgtcag cttcaagtga cagtacagat
      181 acatcctcta ccacaagtga tagctcagat tcatcaactt caagcgatag tacagacacg
      241 tcgtctacca caagcgatac acgtcatgca agtgtctcct tctcaaaaac aagttcggat
      301 aacaggacga actttaactt aactaataaa acaagcaatg acaatggaaa caaatcaaaa
      361 agagcacttc ctaaaactgg aagtcaatcg aataattgga taacactcgc aggcgttata
      421 ttacttgtaa tcggtttaag aatcactttt atgagttata agaaatcgaa aaggtaaaaa
      481 aatattcaag ataaaaaaga gcaacgtcgc taacggacgt tgctctttat ttttgctttt
      541 tatcataaat acaagaacta caattcaatt tgtcaaaaaa cacgtagatt tccttctgag
      601 aaatttattt acgtatcgaa cctttcccta ttcagtcttt gcgatccaaa atcagttggg
      661 taagggaaaa gagattctct tttgttcgaa gagaggtggc aggtaatttc tttatttcct
      721 tcaaagcctt ttctgtgtaa gaggccgcta acttcctagc ttcttccacg cctcctgtat
      781 gttcaacgat tttgcgtacg gcgtcgacat cttcttctgt cattgccgct ttcttctcta
      841 aataaggtag tagctttggt ttgttttttt gcaaagagta gatcaacggt aaagaataga
      901 ccccttgacg catgtcttct agtacaggtt tgccgatttc ctggctctct tttgtataat
      961 ctaaaatatc atcgataatc tgaaaggcca tcccgataga aagtccgata tctcctgctt
     1021 tttttgcgaa gcgctcgctt gttccacttt caaaagcgcc aacagaacaa cttaattgga
     1081 acagttcagc tgtcttacct gaaatatttt ccaaatattc ttttacagaa agttcataat
     1141 tatagcgatc atccatctgc cctaattcgc cattcaatac tttttccata ctgcgagaat
     1201 tcaattggag acttttcaag gaagtggagt aatcagacaa tagtttaaaa cagcagacaa
     1261 ataaatagtc tcctgcatag acagaaacga cattaccaaa ctgactacgg atattaggct
     1321 gaccacgtcg cagatccgct tcatcaacga tatcatcatg gatcagtgtg gccgtatgga
     1381 gcatttcgat agaagctgcc aaagcgatgg ctttgtctcg atcttgctct ggtccaaatt
     1441 gtgagaacaa tagctgatag gcaggacgca acagctttcc gccggcatgg atcgtttctt
     1501 tgattgcttg ttcgacaggt ttgtttttca ggcggacagt ttcttccatc cgttttagtg
     1561 tttctgtcaa ttctttactt aaagcaggat agttttccca cattggatgt agcttcataa
     1621 aaaaactcct tgtgtgacga ttattttttg gtaaacattg ggctccattt ttgtttggtt
     1681 ccctgctcat aatctttttg gaatcgttga agtgtctgca catgtcgtaa aagataattc
     1741 gctgcgatcc cgattgcaat ccctgataaa atccctaaaa ctgaaaggac tggcaagtac
     1801 aacatgactg tccatgattg tgcaatgaaa gaagccatca aaagctgtcc gacattatgc
     1861 atgaaaccgc cggccgcact aattccgatg atactgacac gttttggtcc taattgcttg
     1921 accaataaca ttccaaaata actaagcaaa gcaccactca tactataaag gaatgtggaa
     1981 atcgttccgc ctagcaaagt agtcaggaat agtcgtagcc aaagtagtaa gaagctgtct
     2041 cgttttttca tggtaaaaat ggcaacgatc gtgattagat tggctaagcc tagttttgca
     2101 ccaggcgcaa aagaaaaagg ataagggatc atattttcca ataaaccaat gatcactcct
     2161 tgtgcaacaa gtagcgaaat ataaatcatt ttttgtaatt tactcatggt gtgtgaaggt
     2221 ctaataaatc agactgtctt cgtcacctcc atctgttgaa cggacttcga tcactaattt
     2281 atgtggcaaa cagacgatgg tttcgccatt tttcgttgcc cagcctcgac gtacgcagat
     2341 ctggtcatcg caatctgctt cttttatccg tactcgatcg ccatctatct cgatcaagtt
     2401 ataatctccg tgttcatctt tgtaagtata tgtgttgctc tcttctccag ccatcaaagg
     2461 gaatgttttg atttctgtgc catccacacg cagtaccgct tctttttctg ctgttgcggt
     2521 gttttgctga agaccaaaaa tcatgactgg taaaaaagaa agaacagtca aaagcaaaat
     2581 aataaaaaca tcccaaggtt tgagcagact tttttcagca aattctttaa ggctcatttt
     2641 tgttctcctt tttccagatt aactcaccca attttagcat aaaaacaaga ggttgtgaca
     2701 cctgtgtctt gctttgagta ataagaacga agaatagaaa acagctttcc atgttttcta
     2761 attctttggg cttattaccg agaagcagca ggtggaacac cgtttataac aagaggttgt
     2821 gacagaagtg ggcaacttca agaaataaga aggaatttac gaaaattact tttcaagttt
     2881 ttgtgaaatt tcggcttatt tttcgaagaa gctacttctg gaacaccgtt tataacaaga
     2941 ggttgtaaca gaggttgtga cacctgtgtc ttgctcatgg aggcttatct cgggcatctt
     3001 attcctttaa ttttacataa aaaggaggct gtgacggttt gtctcagccc ctttctattg
     3061 aaatcttgca ttcaaataac gttctttatc tatttatttc ttgccgtact gggaacttgg
     3121 tctaccgtac caccaattac ctagtgtacg ttgtagccat ggaattaccc agcgatccaa
     3181 cccaatcgca cgtccggaac cgttcatcaa tgcgaaagca acaaaaatga accaaatgtt
     3241 tacccagtaa aacatgcctg ataagcagaa cgtgatcacc aatacaatcg ttgtcgcact
     3301 gcatagccat gtgaataatc cagcaatcaa tgctaatgcc aaggcaattt caaagaatac
     3361 catgaatttt tggaagaaca ttgctacatc attgtttggc atgatcactt gcatgatctt
     3421 tgtgaaccag tctggtgact tctcaatcac agccattggt tcttcaccgt atgcataact
     3481 caaaccaaaa tgtgcagctt gagtcgctgc ttctccggca cttgcccctg ctccgctggc
     3541 agctgtggtt gcatcaccag cagcagaagc accactggca acatctgtta cattgtattc
     3601 ccatgtccaa gggaacacac tgtttccagt gaaccatgat ccttcaccaa accaagtact
     3661 tggtttgaac acttcaccat tcccaatgat ttttttggaa gcttcaacga accaaactaa
     3721 accatagaaa atacgaagtg gcacactcca taagacattg ccgtaacgag aagaatgtcc
     3781 tcgagtcacg ttgcgatcat ctttgatatg gaaaaactca tgcattaaat attggaacat
     3841 ataataacca gaacgaatat caaagaagta tttcaaattc acgatatgtt tcattacgat
     3901 agctaaaaat ccgcttaaat ggatcttatc aaataggtta gctacccccc atttggcacc
     3961 aatagaaacc ataaatcctt gatagtttcc tttaaattta tgcttttctc cgcctttgat
     4021 cgaagccacg atattcgctg cggctgtgtg tcctgtttgt tcagcagctt gaacgatctg
     4081 cggtgtcggt gttcctggga attcttcata aaagactaaa tcaccaatga tatagatgtt
     4141 tttatcttcg tagccttttg cctgcatata ttcattggcg atcaaccgct gtccgcgtgc
     4201 tgattctaat ccaaagtcag cagcgtcaga agttcctttg acaccagctg tccaaatcag
     4261 tgtgtgagtc ggaatgttgc gtccgtcttt caatttgata tgatcagcag ccacttctac
     4321 gattggtgca ttcaataata attccacgtt gtgcttacgc aaatagcgtt cagcttttgc
     4381 agcatcattt cgatccaaca tattcaagat cgtcggcatt gcctctacga ccatcagtgt
     4441 gatttcgttt ggatctaatt tataatcttt ggctaggcga tttttccagt cgatcagttc
     4501 cccaatcatt tcaataccgg taaatccaga accacagaca acgaaagtca gcatggcttt
     4561 acgcagttca tcatctggtt ccaatgcagc ttttgctact gtcttctcaa tatgttcccg
     4621 aatccttaca gaatcttcaa atgaccaaag ggtgaatccg tgtgctttga caccaggtgt
     4681 accaaagtca ttcggctctc cgcccattcc aaggatcagc tgatcaaaag gataggaacc
     4741 taatttggtc ttgacgattt ttcgttcttt atcgataccg attacagtgt ctgtgacaag
     4801 ttgtacattc ttttgacgag caaacaaatg ctgcagatcg tattggattg cttctggttc
     4861 tacacgtccg ccagctactt catgcaactc ggtcatcata gtatggtacg aatgacgatc
     4921 gatcagagta attgctacat cttctttttt cagtttcttt gccaagtatt ttgtagctga
     4981 aacaccggca tatcctgctc ctacaacgac aatattttgc tttgccattg atcatccgct
     5041 ccttatagac tatctatata atgaatatat gataattctt ttagtttgat acttattaca
     5101 caatctccat atattatata gatgttctgt tcttttgtct aactcctttt ggattttttt
     5161 caaattttaa aataaagcgt tttttcacga aatttgctga aagaaaacgt ttgaaatatt
     5221 acatgggtta tttatcaaaa atagttgact tataggctaa aaagattaga atgtataatg
     5281 aatcacaaag aaaaattgtg gactagaaat ggaatggtgg ggtattaaaa tgaagaaaaa
     5341 acgttttgta actggatttg ccgtattagc attttcagct ctagtgttag gcgcttgcgg
     5401 cgcagatgac aacggaagct caaactcttc ttctgaatca tctacagcac aatcttcgac
     5461 tgcaaaaagc acaacagaat catctgcaaa agttgtagct ggcggagatt tgcaagacgg
     5521 cacatataaa ttagaagaaa aaaattattc aaatggttac cgtgcagtct ttgaaatggt
     5581 tgtaaaagac ggcaaaatca ctgaatcaaa atatgataac gtcaatgaaa acggcgaatc
     5641 aaaaacaaaa gatgcagaat acaacaaaaa catggaagca aaatctggca caaacccaga
     5701 aaaatacatt cctgagttga atgaccaatt cttaaaagca caaagcgcaa gcggtgtgga
     5761 agtcgtaact ggagctactc actcatctga aagcttccaa aactacgcac aacaattgat
     5821 ccaagctgct caagctggta acacagatac aatcgaaatc gacaatggtg ctgatttgaa
     5881 agacggcact tacaagcttg aagaaaagaa ctactctaac ggctaccgtg tgcaattcga
     5941 aatgacagtt gctggcggca aagtaactga atcaaacttt gattatatcg acaaagacgg
     6001 taaatcaaaa caagatgata cagaatataa tgaaaatatg aaagcaaaaa gcggtacaga
     6061 accaaaaact tacatcccta ctctgaacga cgaattcgtc aaagcaatgg gcgaagaaga
     6121 tggctcacct gctaatgtag aagttgttac aggtgctaca cacagctcac attcattcat
     6181 catgtacgca caacaattag tgaatgcagc tgaaaaaggc gacactcaaa caatcgaagt
     6241 agataatatc gtaacagaaa aataatcaca taatcatact aataaaagtt ggagggtggg
     6301 acgatagcca gattaggcag tcgtctcacc tttcaaaatg aagagaggaa aaagatgcgg
     6361 aaaaaactac tattttcctt aatcacactg ggcatctctt ttatggtgct aactggctgc
     6421 agcaactcag caaataaaac aaccactgaa agttcagcag ctaccaagat attgaaagat
     6481 ccatattctg atgaacagtt cttgttaggg acttacgttc gtatccgtgt gtatgatgaa
     6541 ggcaaagaat cagcattgaa acctgccttc gatcgagtaa aagaacttgg tgataaaatc
     6601 acgatcaatc aaaaaggttc tgagatcgat gaagtgaatg agcaagctgg gatcaaacca
     6661 gtaaaagttt ctgatgacgt ctacacgtta gtcaagcggg cctacgaata tagccaagat
     6721 tctcaaggcg gattcgatat ggcgattggt gcaatcacac aattatggcg aatcggtttt
     6781 gatgacgcca gaaaaccttc ccaagaagaa atcgatcagg cattgaaatt agtggattat
     6841 cataagatcg aactaaatga caaagaaaaa actgtttatc taaaagaaaa aggaatgatc
     6901 atcgatttag gtgcaatcgc caaaggttac attacggacg aagtagtgaa agtcttgaaa
     6961 aaacaaggag tgaccactgc catcgttgac ttgggcggta atgtctatgt cttaggccac
     7021 agcccaagag gcgaaaacca agactggaca gtcggcatcc aagatccgaa catggctcgc
     7081 ggatctgttt taggttctat taaagaacgg aacaaaacat tagttacctc tggaatttac
     7141 gagcgttatt tagaagtaga tggcaaaaaa taccatcatt tgtttgatcc aaaaacgggt
     7201 tatccgttcg acaatgatat cgcaagtgtc acgatcataa cagataaatc aattgatggt
     7261 gacgggttgt ctacagcagt cttttcaatg ggtgtgaaaa aaggactgga atacgtcgaa
     7321 agcgaattga ataacgggac ggaagcgatc ttcgtgacaa aagacgataa agtatatgtg
     7381 accgatccaa tcaaagacac cttcaaatta tcggaggact cccattacac gatgggtgac
     7441 cgttctgaac taaaataagg agtacgaacc atgacactaa aaatcttttt agaagtagtt
     7501 gaaatacgaa caaaggtggc tagtgtattt ccttttgcgg taggggtatt attctctatc
     7561 gctttttttc atgagataca ttggctaaac acttttttat tttttattgg aatgctagtt
     7621 tttgatttag cgactaccgc tatcaataat tacatggatt atgaaaaggc tcattctgaa
     7681 gtatataagt atgaagaaaa tgtcattggc cgcagaaatc tatctcctgt attgattcga
     7741 aacatgattt tagctatgat tgcatttgtt tttgttatcg gcgttattct aacgatcaat
     7801 acgggttggc ttttactttt gatgggattt atctgttgtt ttattggagt attctataca
     7861 ttcggaccga ttcctttatc tcgaatgcct ttaggggaaa ttttcagtgg ggtgactatg
     7921 ggccttggaa tttttgccat ggtcgtttat gtcaatacat tcggttcaga tgtctatgat
     7981 ctgacagtca acttttcatc tggacaattt gctttggtag gaaatctttg ggctatagca
     8041 gcaatcgtat tagcttcctt acccttggtg tttacgattg ccaatatcat gttggctaat
     8101 aatttgcggg atcttgaccg tgatattgaa aatcatcgct atacactagt tttttatatc
     8161 ggacgtcctg cgggaacagt cttattccag ctattgatgt atgcttgcta tttcgtgatt
     8221 ttaatggggt tgttgagcgg tatctatgaa tggccgatct tggtcacctt cttgaccttg
     8281 ccaattgtga agaagcattt ggatcaattc aagcaaacgt taccccagcc tatcagtttc
     8341 agctattcca tcaaaaatat ggtcttattc aatgccagtt atgtattggg gctattacta
     8401 acaatcatta tgcaagccat ttaacagcat gaagaggttg tgaaaaaact gccctgcatc
     8461 aagtaataag aacagccaaa taaaaatagc tccttatatt tttcgtttgg ttgggcttat
     8521 taccgcagat gcaagctttt gaacaccgtt tatcaggagg ttgtgaaaaa gtcgcttagt
     8581 ttcgagtatt aagaaaaatt ttgtgaaaat ggctttccac atttttgcat aaatttggct
     8641 taataccgag aaactggctt ttgaacaccg tttatcagag gttgtaaaat cagtgttttg
     8701 tcctgagtat tagagaaaca aatggaaaaa tagttcctca tattttgccg ttttttgagc
     8761 taataccgaa ggacagctga ttgaacacta tttgttcgga aaaagtgact aactatgaca
     8821 caattttttt cacagtccct tttttcactt gatttgattc gtaccagcga acttgacgag
     8881 aactttcttg gtttggtaac tatatggtat tcttttaaca tcctcgtttg cttcttctaa
     8941 tttatttata caaagtcaca cttttttaaa catctgttct tcgatacatt tctatttctt
     9001 ttaaacatcg ataccaatat tttgaactta agagtgcata ccaaatggat tcatttactc
     9061 ttcgtcagtt acgaagataa tcaaaatctc caacttccct acttatttcg ttttgagaat
     9121 tatcgaagca atcttacata aataactaaa aaacaaaaaa ccagaaaatc agtatactga
     9181 ttttctggtt ttacatggtt tgttcaataa aaagctgttg gaactgttaa tattaaatta
     9241 tcgcatcgtt acgaattctt ccgctcctgt tggatggatg gctactgtat tgtcaaagtc
     9301 ttctttagtt gcacccatct tgatagccac ggcaaaacct tgcagcatct catcgacacc
     9361 aacaccaata gcatgtaagc cgacgattct ttcttctttt ccgacacaga tcaatttcat
     9421 ttcgcatttt tggcgataat catttaatgc aaagtacatt ggggtaaagc gtgaacgata
     9481 aactttcaat tcattttcgc catatttttc caatgcttct tcttctgtca aaccaattgt
     9541 tgcaattggt ggatgcgtaa agacgactgt cggaacaagt ttatagtcaa gataagaatc
     9601 tttctttcca ttaaataaac gttctgataa acgtctacca gctgcgattg caacaggagt
     9661 cagatctaat ttaccgatca catcaccaac agcaaaaata tgttcatccg ttgtattttg
     9721 gtatttatct actttgataa accctttttt gtccaattcc acatttgtat tttccagacc
     9781 taatttttcg gtattcggta cacgtccacc ggcaaaaagt acacaatcac cagttaaggt
     9841 ttcaccattt tcaaatagca ccgtatattc gtcattgttt ttagtaattt ctttagcaat
     9901 atgatgtgcg taagttttta ttccagcttc ttggtacatt tggatcaaat tgtccgaaag
     9961 cattttatca aacgttctaa gtggtcgttc ttttcgatat gcccacatga cttcactacc
    10021 taaaccacga aatacacctg aaagttcagc cgcaatgtat ccagcaccta aaacgattgc
    10081 tctcttaggt aactctgtta attcaaaaaa tccatttgaa tcaattgcgt attctccacc
    10141 aggaatggtc attttacttg cacggcctcc agtagcgatc aagattttag gagcacgata
    10201 ggtttcaccg tttacttcga tcgtttgact atcgataaaa gtagcgtaac cttttatagc
    10261 ctcgacatga ttgctatcta atcctctttg ataagcaccg tgtagaaaat caatatattt
    10321 ttctcgtctt tctactagac cggcgaaatc aacatttttt aaatctgctt ggataccgta
    10381 acttgaggca tctcgttcaa ttgtttccaa aatcgtactt gcttgccaca taactttttt
    10441 aggtacacaa ccgacgttga cacatgttcc gcccaattca ttcgcttcaa tcagcaaaac
    10501 ttttgcgcca tgcatccctg ctctgtttgc tgaagcaata ccgccagagc cgccaccaat
    10561 tacgatgtaa tcatatattt gcattttgtt cctccttatt gaagagatca atcaaaacct
    10621 ttatttaacg atcctttttc tacagaaaac aagtgtaaca cttttcttga attttgtatg
    10681 cgaagatgct taaaacaggg atatatcagc tttttcctta tttacgtttt cggatcatat
    10741 ctccaggttt caccggctgt gcgactggca tagttaaaat catcattgga tttggtgctc
    10801 ggtcaatgga ttcgccttct tcattatgca taacttcaac ggtttgactg aaatgactga
    10861 atcctggacc ataaaattcg atttcatctc ctacagaaaa caagtttctc tgacgtatcg
    10921 tagcaatctg tgttgcctca tcataagata atacttcacc gacaaattta tatactggga
    10981 ttttacgacg ttcaccgaat aattgttcgt tttcagttgg tgtattgtag taaaaacctg
    11041 tagctaattc tcgttgtgct actttccata actcgtcgat ccattcttgc ttgcagacat
    11101 agttttcagg atcttccata taactgtcta cagccgcttt atagacattt gacaccgtag
    11161 atacataatg gatcgatttc attcttcctt cgatcttgaa gctgtctacg ccgttttcaa
    11221 tcaattctgg aatatgttcg atcattgaca tatccactgc actcatcgag aattcttctt
    11281 ccacttcgcc tgtatcagtt aaactgtttc gttcttgacc aaaaggcata tcgaacaatc
    11341 catacttcca gcgacaagat tgagaacatc cgccacggtt tgcatcccgc atcgacatat
    11401 ggttggacaa tgtgcatcga ccagaataag agatacacat ggcaccatgg ataaatgctt
    11461 cgatttcggt atccgtattt ttacgaatct ctgccacttc ctccattgaa acttcacgag
    11521 ctaaaacgac acgttccaac ccttcttctt tccagaattc caatgtctca aaattagttg
    11581 ctgaagcttg agtggataaa tggatcggca gacctggggc ttctgtcgca caaatttcga
    11641 tcaaagctgg atcagaaaca atcactgcag aaataccgac atcacgcaaa ctgcggaaaa
    11701 attcccctgc tccatcttca tttccttcat gggtgaccat attagcagca acgtatacct
    11761 tcgcatcatg ttcttttgca aaagcaactc cttcagccat ttcttcataa gtaaaattac
    11821 ctgcacggct tcttaaacca tatgcattcc cgccaatata tactgcatct gctccataat
    11881 ggatcgcggt ttttaacttt tccagtgttc ctgctggcgc taggatttct ggtcgtttca
    11941 attttctttt tactgtcatt tctttcatca tactccttat ttgatagcag aaggatcaat
    12001 ataaaagaat cctgtatcta attcacggtt ttcaggatgc aatttactga tttcgctagt
    12061 cattttttcc gctttttctt gatcccagct accttctaaa atttgttttt ttgcttcggc
    12121 gaatagtcga gtgatgttta cgaatttttc gcctggagta aataatccgt ccaatttcca
    12181 tgtacagtaa tgatgctgat aaagttcatt caattcattc gagagattca gatcattgct
    12241 ggcaaaaata tgtgtgccat gactatcttc ataaatagaa taatgtgtct cttctttttt
    12301 aggttccgag ataaaaagac ctctttcacg atctttttgt tcgtcttgtt tcgtatagtt
    12361 atagtaattc tgtagcagtg gacgtttgga ttgatggatg catgtagcac catacacaag
    12421 ggtttctaca ggaatatcga gtttttcttc catcgccttc atctcttcaa aaggaacttc
    12481 acgagcaagt actgctccaa ctgcgccttt tttcgcccag aaattgattt gacgtgcgct
    12541 cgttactaat gtttcagcat cataaatata cggtatacgc aattcaggat tttttttcat
    12601 cgtataaata atacctgtat caccaactgt gatcacatct acgtttattt cttttaaaaa
    12661 agccaaatat tcaggtacat ttttcatttt ttcaggatga atgatcccat ttacagcaat
    12721 attcgctttt ttaccatact tgtgtgctaa ttctaccaat tgtcgctgtt cttctcgtgt
    12781 aaatgaagca ggcagacgca atccaaattg ctcttcaccg aaatatagtg tatctgcacc
    12841 tgcagcaagc aactgttctg cttgttcaat agtttctact gtggttatga gttcgatcat
    12901 aattttctcc tcctacaact tcataatagt agcatagctc taaaaacttt ccaatacttc
    12961 ttctatttaa agtcggattt ttgaaaatta tttcacaaaa aatcaaaata aagttcgata
    13021 tattctgtcc aaatataaaa agagattgtg acaaaaatct tgtcacaacc tcttaatcaa
    13081 gtcttactat tataaaaatt cagctacaca ggccaagtaa ctatagggaa cctactgttt
    13141 cctttttagg tccgcgaaca ttcaatgtga tcttaccttt tgaagcacct actgttacgt
    13201 ggtcacctaa acgaatttct ccgccaagca aagcctcgct caatcgatct tcaatttctt
    13261 tttgaagtgc gcgacggatt ggacgtgcac catattcagg atcaaatcca gctttcccga
    13321 tcacatcgat tgcagatggt gtgattttca cttgaatatc ttgttctttc aatcgtttga
    13381 taatcgcttt gctcatgatt tggacgattg tatggatttc atctttactc aatgaatgga
    13441 agacgacagt ctcatcgatt cgattcaaga attcaggtcg gaaagctttc tttaactctt
    13501 ctaagatacg tttttgcatg gctttgtgat ctttagtaac atcttggaca ttgaatccga
    13561 catttttttc ttctcgaatt tgtgtcgctc cgatatttga agtcataatc atgattgtat
    13621 ttctaaagtc cacttttcta cctttagaat ctgttaaatg accatcatcc aatacttgca
    13681 gaagtaaatt gaaaacgtct ggatgtgctt tctccacttc atctaagaga atcactgaat
    13741 atggtttttg acgaattttt tctgtcaact gtccaccttc atcataccct acgtatcctg
    13801 gaggagaccc gattaatcgg cttgtactgt atttttccat aaattctgac atatcaacac
    13861 ggatcagggc atcttcactt ccaaacatga cttctgaaag tgctttggcc aattctgttt
    13921 ttccgacacc agttggtcca aggaacatga atgaaccaat tggacgatca ggatctttca
    13981 atccgcttcg tgcacggcgg atcgcacgtg aaactgcttt gacagcctca tcttgaccaa
    14041 cgacacgttc atgcagaagt ccttccagtt ctaacaagcg ttcgctttct tttttctcca
    14101 actgctgtag agggacacca gtccactccg atacaactgt agcaacatct tcttctgtta
    14161 cacgatcaga ataaccttgc tcctgttttg cttcaattgc agaaactttt tgcagctttt
    14221 tacgtagtgc tttttcttgt ctgcgtaatt gagcagcatt ttcaaagtct tgtttttgga
    14281 tcgctgcttc cttttcttgt actagttcat cgatttctag tttgatcaca gttgattttg
    14341 ttaagtgatc ggtttgatcc aaacggactt tcgctgctga ttcatcgatc aaatcaattg
    14401 ctttatcggg tagttgacga gaagtgatat aacgaacaga aagattgact gctgctcgta
    14461 cagcttcatc tgtgatctcc actccatggt gctcttcata tcttgtacgt aatccttgaa
    14521 gaatcacttc tgcttcttca ggagttggct catctacttg aatgcgagca aaacgtcgct
    14581 ctaatgcaga atctttttcg atatattttt gatattcatc tagggtcgtt gctccgatcg
    14641 tttgtaattc tcctcgagct aacgccggtt tcaagatatt cgaagcatca attgctcctt
    14701 ctgctccacc tgcaccaatt aaggtatgca attcatcaat gaataagatt acttgaccat
    14761 cattatagat ttcgtcgatg acctttttca ttcgatcttc aaattcaccg cgatatttcg
    14821 taccagcaac caaagatccc atatcaagca tcatcaggcg cttttcttgc atgtcttctg
    14881 gcacttcacc taaaatgatt ttttgagcta acccttcagc aatggctgtt ttgcctacac
    14941 caggttcacc caccagtaca gggttattct ttgtccgtcg gctaagaatc tggataagcc
    15001 gtttcacttc tctcgaacga ccaacaactg ggtccagctt gttttctttt gctaatttcg
    15061 tcaaatcacg tgctaatgaa tctagcgtag gtgttccttg cggtgtttgc cgtttatctt
    15121 gtacatttac atttctacga cgattcattc cttttccagc agaatcacca gctagcccca
    15181 ttttttgttt cagaacttga cgggcttttg aaaggctgat acctaagttg atcatgattc
    15241 gagtagccat gatactttca tcttttaata agctcatcaa aatatgttct gttccaactt
    15301 tttgagaacc agttttcttc acttcgctgc tagctaaagc aaaaacttgt ttcattcttg
    15361 gtgaatatgg aagaaagact cctttagggt aagaacggat accaccataa ccaatcagat
    15421 gttcaatttc ttcataaatt tccgtttcat tcaaatccat ttcacgtaat acttttccag
    15481 caattccatt ttgctcgacc actaaggcta gtaaaacatg ttctgaacta actgattgat
    15541 gtttcaaccg ttttgcttct tcttgtgcaa tttctaatac tgcttgggct ctttcagtaa
    15601 aaagttcttc catctaatct cacttcccat cttcataact taaacgttcc agaaatgctc
    15661 ggagaatccg agcacgtgta tgatcttcat attcattgaa attcaatgtg ttttttgcaa
    15721 ttgcactcaa catcaagttt ccttcttttt ttgtaattat ttggtcttca taaagttttt
    15781 gaataatagc aaaagcattt ttctcactga ttgtatcatc aaataactga tttatctgct
    15841 caagtaattg ttttttatct gaaatcctta cttttgcaat tcgtatataa ccaccaccac
    15901 cacgtttgct ttctactaga taaccacgtt ggatggtaaa acgggtatta atcacatagt
    15961 tgatttgtga aggaacacag ttaaagaggt ctgccatttc aatccttcga atctcgatca
    16021 tttcactatt ttccagaatt ttctttatat atgattcaat taaatccgag gtattctgat
    16081 gtgccatctt attcattccc tttgactaat attgacctta attataacga atttgataat
    16141 agaaagaaag aagaacgctt tttgttaaat aaatccttta gaatcaacaa aaaaaaatac
    16201 ggaatatact attccgtatc
//
LOCUS       DAFLVO010000065        15241 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.065, whole genome shotgun sequence.
ACCESSION   DAFLVO010000065 DAFLVO010000000
VERSION     DAFLVO010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15241
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.065"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(94..1137)
                     /locus_tag="L1U99_002192"
     CDS             complement(94..1137)
                     /locus_tag="L1U99_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBN1212724.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(1514..2479)
                     /locus_tag="L1U99_002193"
     CDS             complement(1514..2479)
                     /locus_tag="L1U99_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBN1212725.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            2713..3558
                     /locus_tag="L1U99_002194"
     CDS             2713..3558
                     /locus_tag="L1U99_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1212726.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            3749..4936
                     /locus_tag="L1U99_002195"
     CDS             3749..4936
                     /locus_tag="L1U99_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBN1212727.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            4942..5298
                     /locus_tag="L1U99_002196"
     CDS             4942..5298
                     /locus_tag="L1U99_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBN1212728.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            5300..5638
                     /locus_tag="L1U99_002197"
     CDS             5300..5638
                     /locus_tag="L1U99_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HBN1212729.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     misc_binding    5714..5970
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6033..7067
                     /locus_tag="L1U99_002198"
     CDS             6033..7067
                     /locus_tag="L1U99_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1212730.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            7060..7746
                     /locus_tag="L1U99_002199"
     CDS             7060..7746
                     /locus_tag="L1U99_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1212731.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            7770..8618
                     /locus_tag="L1U99_002200"
     CDS             7770..8618
                     /locus_tag="L1U99_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBN1212732.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            8815..9588
                     /gene="sufC"
                     /locus_tag="L1U99_002201"
     CDS             8815..9588
                     /gene="sufC"
                     /locus_tag="L1U99_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HBN1212733.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            9601..10887
                     /gene="sufD"
                     /locus_tag="L1U99_002202"
     CDS             9601..10887
                     /gene="sufD"
                     /locus_tag="L1U99_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HBN1212734.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            10884..12119
                     /locus_tag="L1U99_002203"
     CDS             10884..12119
                     /locus_tag="L1U99_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBN1212735.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            12106..12576
                     /locus_tag="L1U99_002204"
     CDS             12106..12576
                     /locus_tag="L1U99_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HBN1212736.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            12581..13972
                     /gene="sufB"
                     /locus_tag="L1U99_002205"
     CDS             12581..13972
                     /gene="sufB"
                     /locus_tag="L1U99_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HBN1212737.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(14070..15212)
                     /locus_tag="L1U99_002206"
     CDS             complement(14070..15212)
                     /locus_tag="L1U99_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1212738.1"
                     /translation="MATFFSYKLQNGEKYWGFETYLGKDPKTGKDIRTKRRRFKSKAE
                     AQTALNRLLVDFKEKQEFKINVTTFQELYELWIDNYRTRVKPSSVAVAQRFCKNHILP
                     AFGELRLDKISVSYCQKQVNEWHKTLKQYGFLRKTTAQIFKFGVAMEVCKDNPMSKTL
                     LPRKIEEEQPLKFYTKDQLQLFLQNTKENNSVKLYTFFRLLAYTGMRKSEALALQWED
                     IDYFNKTITIGKTIAQDEFNQVVLQVPKTKNSSRTIQLDDFTLKQLRIWQQEQMKIMI
                     LYGYNTNSPKQFLFTTNTNKLYYPQVVNDWLDWIYKKTPMEPQITPHGFRHTHCSLLF
                     ESGASIKEVQERLGHKDIKTTMNIYAHVTPQSVKKTGDRFAKFMGE"
BASE COUNT         4979 a         2846 c         3253 g         4163 t
ORIGIN      
        1 tgttgttgtt agaaggatat ctgcaaaatt aaaaacagtt gtgattcgga cattgttcca
       61 tgcgagaatc acaactgttt tttcatgttc attctaaact ttgatcagcc aaataaatag
      121 taaagccatc actgtttgga gaagcccgac agctaatcca taagataaga agcgtgtacc
      181 ttctttcatg aattttgcaa agtctaaacg cagaccaatt gccgctaaag cagtgatctc
      241 aaaccagctg ctgataaaat gtgccgattg gtcaataact acaggtaaag aaaacaagct
      301 gttgaccaaa caaaagatca caaaccctaa tacataccaa ggaagcggta attttcgttt
      361 tttctgcgta tcagttggcg tttcaaacag agctggttgt ttcttgtgca tgaatttttc
      421 aaacagatag acaacaacaa cgagcatcat aatacgtaga atcttaaata gcatggcgaa
      481 ttcgacaaca gaattgtcaa gtaagcttgc cccagcgact acttgaccaa cagattggag
      541 tgtaccaccc aaaagtgcac ttttttcaat gagatttcca ccaaacaact gtaatccaag
      601 aaaagggaga gtcaacatca tcacagtacc cagtagattg actagtgtga tgatctgtcc
      661 tttttcttcc tctttcgcat ggatggaagg ggcgattgaa gcaatagcag aagaaccaca
      721 aacagcgttt cctccagcca tcatcaaaga agaagtatcg ctgaattgca gttttttacc
      781 aatcaagtaa gcaccgatga tagtgactga catttgcagt aacacaaaaa caattccttt
      841 tacaccaatt tgagcaatcg tttgagctgt gacagttgca cctagtaaaa aaacagagaa
      901 ttctaatagt ttgctttcag caaattttgt gccgattgct agaacaggct gtttaaaaaa
      961 agtatttcct aataaaatac ccaataaaat agcaatagtc gctccaccta actgtggcag
     1021 ataaatagca agaagcctgc tgaaggcagc gatggcaaaa gaaagcagta aaccgggtaa
     1081 gatttcgcgg accgctgaat cctttacaga ttttattgga tgtgacaatg atttcatttg
     1141 atcggttcct ttcgtcaata aatactaaaa gcatactcga acatagtagc actaaaccag
     1201 tattttgaca aaagaacaag aggtcgtgac aaaagtcttg tacgacctct tgtttcgaat
     1261 aaacggtgtt ccagaagtag cttctacgga aataagccga aatttcacaa aaatttgaga
     1321 agcaattttc gtaaattcct tcttatttct tgaagctgac cacttctttt acgacctctt
     1381 ggtaaacggt gttcaaaagc ttgcatctgc ggtaataagc ccaaccagta caaaaacatg
     1441 aacagctgtt tttgtttggc cgttcttatt acttgatgca gaacagcttt ttcacaacct
     1501 attgaatcga ttattaagcg atttttttag aaacaaattt tccatgtttg ctatgttctt
     1561 taattaagaa acgtacgtaa tgagcaagaa cgtagaagac aactacactt gcaaacagac
     1621 attccgcaac ttttaagaaa tccaatacgc tactatagat acctaaactg ttgaagtaat
     1681 gaacagtagt aaatatagct gttgcagaga taacaagcgg gaatgtaaag gctgcatagc
     1741 ttggataaaa acgaagcttg aacaaacgtg gaagcataga cagcacaacg aaatacaata
     1801 cttgagataa agcgaacaat gctacgacaa gataaaaatt aggttcagca aagtttttaa
     1861 gataacctgt taggcaaaga gaaccaggtg ctgcaacgat cgtaatcagc ggacgtgtcg
     1921 gatgagccat atttcttacg aaaaagacac gtttgatgat gatcggcaat aagaacgcat
     1981 agcagatcaa tgaaatccaa aagaaaattt ttccaataag tgggaagaag ttcccggcag
     2041 ttacagtgat gaccccaaat ccaacgtaaa tgataaacca gcttggataa attgcttcaa
     2101 ttgaaagatc agctttgata acatggtgat aattgaaata aaagacaagg atcacttgga
     2161 agataacagc gcacagccaa atgaatttga caattggtgc aatactttca tatgaaacaa
     2221 aataagtaca aataaccatg agtgacatcg taaaagttgg tgaaacggag gcgatgattg
     2281 gatcatgcaa cgtttgtttc gtgtgttcga ataagataaa caatttaaca aaaatgaata
     2341 tcataagaat catagagata ccgccagtta gattgcctaa agcaacatgg tgatagtctt
     2401 taaacagatt tccaagggaa gctaacccaa ggatcaaccc gcagatcggg atcggaataa
     2461 ttttcaaaaa gttcttcata tataatattc tcctttttat ttaatagatt ttagtaccaa
     2521 gatgaacgaa tacattgtaa aatgaatagg aatgtatgat tacgagcaag cagacagctg
     2581 attgtcttca tctaagttac tagttggatc agcaactgtt ttgttgtaca tttctattat
     2641 agatggtttt ttgtatattt aaatcaaata gtttttatag taattatcat aaaaagttat
     2701 ggaagtggtg ccatgtttaa gttattaacg acttttcgag cagtatatga aacaagaaat
     2761 ttttccagag cagcagaagt actgttttta tctcaaccag cagtctcgaa tcaaatcaaa
     2821 cagttggagc gggaattgaa tatcgatctt tttcaacgta acggaagaaa agagatgctt
     2881 ccaactaagc aagccgactt attatatgaa cggacactgg ttttgttaga agaatgggaa
     2941 gaaactcagc aaaaattgct caatgaacaa aatgaagaag aagtatgtcg gatcgttgct
     3001 tcccacacct ttgctgtcta tcttttgcct cagttgatga aacatctgat caaaaggttt
     3061 cctaaagtgc attttgagat cgaaatcacg aattctcatg aatcattaga acaagtagcg
     3121 aaacatgaat ccgattttgg ttttatcgaa aagccattag agacttccgg cgtacaaaga
     3181 tactctttga tggaagacca gctagtcatc gctggggacc caaaaagcaa attgtggctt
     3241 gtaagagaag caaactctgg tgtttttcat tacacgcagc gttattttga agagatgaat
     3301 atccaagata agaagatgat cgtgaaaagt aacgatgtaa ttgttgcgtt gctgaaggaa
     3361 ggaatcggtc gctcgatttt gtctaagcgc tctgttccag aaaatgtgcc aatgactccg
     3421 ttgaatttcc atcgatattt ttatttcatc caacgaacca atctggtttc tgatcagctg
     3481 ctagagattg ccgaagagat ccttcgatac aatgaaagca cagaaacttc tcacagcgag
     3541 gagaatctca gctggtagat aattgcatgt atcaaaaaaa gttctatgat acactaaaga
     3601 taagcagtag gcttttgtac tgcatttgct caagcaactg cacaaacgga aagttaattt
     3661 ttcccaaatg tctatggaaa gactttccat tatctaactg gaccgctata ataatcagca
     3721 gtatggtttt taagaaaagg gatgaaacat ggaaaaaaaa ttaaaagctt cgaacgataa
     3781 tcgtattgat tatggcgtga ttttaccagt ctttctgtta tgtttgattg gtctgctctc
     3841 attatatgta gcacttagcc atgatccgaa caatccagca gtcttgaaag gcgtagggat
     3901 gcaagttgtc tggtatttag ttggagcggc agcaatcgtt gtcatcatgc atttgaattc
     3961 caaatggatc tggaaactga ctccttacct ttatggtttg gggttagtgg taatgggact
     4021 cttgctcaaa ttctatgatc agaatttagc tgcttcaaca gggtctaaaa actggtttcg
     4081 attcggtgcg tttactttcc agccagcaga gttgatgaag attgcgtaca tcttgatgat
     4141 ggcactgatc gtaactaaac ataatacgca agtaaaagaa cggacgatga aatcggactt
     4201 ttggctgatt gggaagctct tgatcgtgac aataccggtt ttagcattga tcatggccca
     4261 agatgacttt ggaacgatgc ttgtctttct tgcgatcttt ggcgggattt tcctgatgtc
     4321 tggaatctct tggcgcatca tcgcacctgt agtaatcttg gcagtagtcg ttggagcagg
     4381 aacgatcttc ttggttacga ctgaaggcgg aagagacttg ctttataaag ttggattcaa
     4441 atcttatcag tttgcacgta ttgattcatg gctggaccct ttccatgata cgtcaggaat
     4501 gagttatcag ccggcccaag gacttttggc aattggtacc ggtggcttgt ttggtaaagg
     4561 attcaacgta agcaatatct atgtgcctgt tcgtgagtcc gatatgattt ttaccgttat
     4621 cggtgaaaac ttcggcttta tcggtggtgc attcgtcatt ttcttgtatt ttattttaat
     4681 ctatcgtatg attcgggtgt gtttcgatac gaataatgaa ttttacgcct atatcgcaag
     4741 cggtttgatc atgatgctgc tgttccatgt ctttgagaat attggagcaa atatcggatt
     4801 acttccttta acagggatcc cattgccttt cattagtcag ggaggatcct cgattttagg
     4861 gaacatgatc ggtatcgggt tgatattatc gatgagatac caaaatgaag cacctgcaag
     4921 atcttcaagg aggtaagaaa attgtacacc ttttactggt acccgaaatg ttcaacatgc
     4981 aaaaaagcca aagcgtggtt agaccagcat ggcgttagtt atcaaaccgt tgatatgatc
     5041 aaagaagtac cgaaggcctc aacgattgag acttggctag aaacgagtca agtaccaatc
     5101 cgtcgcctgt tcaacacaag cgggatgaaa tatcgggaac ttggactgaa agatcaagta
     5161 ggcgagttta cggcttcaaa agcgagccaa gtcttatcga cagatggtat gctgatcaag
     5221 cgaccactga tcttacgaga ggaccagctt gttgcaattg gattcaatga aaaaatttat
     5281 gaaggagaac tgatataaaa tggcaggcaa gcatttgaag aaaaaggaca acctttggat
     5341 cttatttaat ggaaaagaat actgtgttgg tttgacaaat gaagcgcaag aagaacttgg
     5401 agacatcacg tttgccaatc tgccaaaagc aggacaatcg ctaaaaaaag atgaacctct
     5461 gatcgaagtt gaagcggaaa aagcggtcaa tgaatttgcc agcccgctaa cgggtacagt
     5521 ttcttctgtt aatgataaaa tcggtgaaga tatcaatatc ttgaatgatt cagatgaaat
     5581 gaatgcgtgg atcttaagtt tcaaagatgt tgatccaaaa gaatttgacg aattataaaa
     5641 tcagaaaatc acttgaaaaa agttgacact gattcttcca gttgctataa tcataagcaa
     5701 tcctatatga aacgagaaag ctttgaaaag aagagtacat gtcacggacg tttgaagaga
     5761 gccctgtttg ctgaaaatgg gtaacgaaaa tgagatggaa gatggtctta gagcagagta
     5821 agcgagcgta agcaaactta ctacgggagt gcccgttaca gcgcgacagt atacggaaag
     5881 aagctaagtc caagtactgg aagaggctgt tattgcgaag taacggtaaa tcaaggtggt
     5941 aacacggaag ttcaagcttt cgtccttttg cttaaggcaa gagggcgaag gcttttttgt
     6001 ttgaaaaatt ataagagaaa gatgtgaatg gcatgtcatt aatccaacta acgaatgtca
     6061 aaaagacatt caatgggaaa aacggaaaca tccaagccgt caatgacgtt tcactaaacg
     6121 ttgaaaaagg ggatatttat ggaatcgtcg gctattctgg cgcaggaaaa agtacattag
     6181 tccgtctcct gaatggactt gagcttccca cgagcggcga agtgatcgta aacgatcaag
     6241 atattacaaa attaaaaaac aaagaattac gtacattccg aaagaaaatc ggtatgatct
     6301 tccagcattt caacctgtta tggtcaagaa ctgtacttga aaatatccag ctgccgctgg
     6361 aattagctgg cgtaccaaag agcaaacgta aagaacgggc agaagaactg ttgcgtttag
     6421 tcgggttaga aggacgcgga caagcatatc cttcacaact ttccggcgga cagaaacaac
     6481 gcgtcggtat cgcacgagca ttggcaaatg atcctgagat cctgctttgt gatgaggcta
     6541 ctagcgcatt ggacccgcaa acaacagaag aagtattaga cttattgtta gcgatcaata
     6601 agaaattgaa tttgaccatc gtcttgatca cacatgaaat gaatgtgatc cgcaaaatct
     6661 gcaacaaagt cgctgtgatg gagttgggga aagtcgtaga agaaggagac gtattgactg
     6721 tcttcagaca accgaaaaaa gaagtaacca aacgctttgt acaacaagac atcgaaccag
     6781 aagctgattc gacagaacta ttagctgaac tcatcaaaga aaatccaagc ggccgtttgg
     6841 caactttgac ctttagcgaa agaaatgcca acgagccagt catttcccaa gcgattcgac
     6901 gctataacat cgatgtcaac gttgtgtatg gaaagatcaa acaagtgaaa gaaggttcct
     6961 ttggttcatt gactgtcttg atgactggtg aaaccaaaga attagatcaa gcagaagtgt
     7021 tcatcaaaga acaaggagta ggaattgagg tgatccatcg tggataaaag cttttcagaa
     7081 acatatctag attttaaaca aatcaacccg gaaacgatga atcaggctat ccttgataca
     7141 ctatatatga cattaatctc aatggtctta gtgacgatca tcggattagt tttgggattg
     7201 atcctttact ctattggacg caaaaacaaa ccgtatgctc gaatcattta tggaatcgta
     7261 tcgatcatca gtaatatttt ccggtcaacg ccatttatga tcctgatggt tttgatcatt
     7321 ccatttacta aagcaatcgt aggcactatg ctaggtgcgc aagcagccat tccagctctt
     7381 gttttatccg cagcaccatt ttatgcccgt ctagtagaga ttgcttttcg tgaagtcagc
     7441 cctggtgtac tggaagcagc agatgcaatg ggagcaagtt actgggaaat catctggaag
     7501 gtcttgatac ctgaaagtat tcccgcattg atttctggat taacagttac aacgatctcg
     7561 atgatcggat ttactgcgat ggccggcgcg atcggcgcag gtggacttgg aggtcttgct
     7621 tggcaggaag gctaccagcg tggtaatcta acagtgacat tcgttgcgac tttaattatt
     7681 ttactaatcg tatttatcgt tcaaggaatc ggtgatttct taactaagaa aacagacaaa
     7741 agataatagg atataggggg atgtaggata tgaaaaagaa aatttttgga tttgcagcag
     7801 cgcttttgct gactgtagga ttagcagcat gcggtaacaa cagcgacagc aaagattcag
     7861 caaataaagc agacgacacg acattgaaag tcggcgcttc accgacaccg cacgcagaga
     7921 ttttggaaca tgtgaaacca ttattgaaag atgaaggaat cgatcttgaa atcgtcaaat
     7981 tcgatgacta tgtattaccg aaccaatctt tggaagaagg cgacattgat gccaattact
     8041 tccagcatat tccttatttg aacaaagaaa tcaaagaaaa aggatatgac tttgtcaatg
     8101 ccggtgctgt ccacatcgaa ccaatgggct tgtactctaa aaaagtcaaa gatgtttccg
     8161 aattaaaaga tggtgcaaca atcattactt caaattctga atcagactgg ggacgcatca
     8221 tcacaattct acaagatgct ggcttagtca aagtcaaaga tggagtagat ctggaaacag
     8281 caacattcga tgatattgaa gaaaacccta agaacttgaa gttcaaccat acgatcgacc
     8341 catcactttt agcttctacg taccaaaatg atgaaggtga cctagttgca atcaacgcaa
     8401 acttcgctta cggcgcaggg ttgaatccat tagaagatgc cgtattgctt gaaaaggaca
     8461 actctcctta cgtgaatatt attgcgactc gtaaaggtga tgaagacagt gacaaaatca
     8521 aaaaactgat tgaagtgctt caccgcaaag aagtccaaga atggatcaca gacaaatggg
     8581 gcggctctgt taaaccagta aaggctgatg caaaataagg tatggaacaa aaaagatgag
     8641 aaataagtct gtaatggctt atttctcatc ttttttatac ctattctaat ttagaaatca
     8701 aaattgttta ataataaata aaagatattt gattttagta aggaaggtca ttgcgcttca
     8761 ttctcaatta gtctaaaatg agtgagaacg aaagagaatt tgggggtata atgcatgtct
     8821 gtcttagaaa taaaaaatct acatgtgtcg atcgaggaaa aagaaatcct taaaggcgta
     8881 aacctaacaa tgaaaaccgg agaaatccat gccatcatgg gacctaacgg cacaggaaaa
     8941 tctaccttat ctgccgctat catgggcaat ccaaactatg aagtaacaga aggcgaaatt
     9001 ttgtttgacg ggaaaaatgt tttagacttg gaagtagatg aacgtgcgcg acttggctta
     9061 tttttagcta tgcaatatcc aagtgagata ccaggtatca cgaatgcgga attcatgcgt
     9121 gcagcgatca atgcgaaacg tgatgaaaac gacaaaattt ctgttatggc atttttgaaa
     9181 aagttagatg aaaaaatggc tttactaaat atgccagaag aaatggctga acgttatctg
     9241 aacgaaggtt tttctggcgg agaaaagaaa cggaatgaga tcctgcaatt gttgatgtta
     9301 gaacctacat ttgcaatttt agacgaaatc gattcaggtc tggatatcga tgctttgaaa
     9361 gtcgttgcta aaggagtaaa tgaaatgcgc ggagacaatt tcggtgcatt gatcatcacc
     9421 cactatcaac gattattgaa ctatatcaca cctgatgtcg ttcacatcat gatggaaggc
     9481 cgagtagtca tgacagggaa tgctgaccta gctaaacgtc tggaagcaga aggctacgct
     9541 ggtatcagta aagaattagg aatcgactat aaagaagaag aagcgtaagg gggagcaaga
     9601 atgaaagaaa aaaactggct cgattatctt gacgcggtaa atgatttttc tttaagtaaa
     9661 ggcgaacctg attggatgag aaccttccgt caagacgcac tagcgaaagc agatgaactg
     9721 ccattgccgc atatcgatcg ggtgaaattc catcgctggt cgttatttga tgtgaaagaa
     9781 acacaaacca tcagtgaaac aggcacgatt ccggcatttg atgcaatgaa agacaatcct
     9841 gtgcttgtcc aacaaggttc atggacgatt tttgaacaac tgcctgtgga attagcagaa
     9901 aaaggagtca tttttaccga cttgttcact gcaatgatcg aatatccaga actagtccaa
     9961 gaatattata tgaaaaaagc agtaaacatg aacgaagacc aattgactgc actccatgta
    10021 gcttttatga acagcggtat tttcctgtat gtgcctaaaa atgtcgtgat cgatgaacca
    10081 ctcgagtcct tattcattca agatggcgca tccgatgagc acttcttcaa gcatgtgttg
    10141 atcgtggcag atgaacatag tgaattttct tatctggaac gtttccagac aaccaaagaa
    10201 caagtagcaa aatcatcagg taatatcatc gtggaagtca tcgctaaagc tggttcaaaa
    10261 atcaaatatt cagccgtaga tcaattagga gaaaatatta cttcttatat gaatcgccgt
    10321 gggcacattt tacgagatgc ttctgtcgac tgggcaattg gtgtcatgaa tgacggtcat
    10381 gtgatcgctg actttgactc agatttagca ggagaaggtg cacacgcaga agtcaaaatc
    10441 gtggcaatca gctcgggcag acaaatccaa ggaatcgata cacgagtaac caataaagcc
    10501 cctcatacga tcgggcatat tttgcaacac ggagtgatcc gagaaaaagg aacattgacc
    10561 tttaatggta tcggccacat cttgaaaggg gcaaaaggtg cagatgccca acaagaaagt
    10621 cgtgtcttga tgctttctga taaagcacgt ggtgatgcga atcctattct tttgatcgat
    10681 gaaaacgaag taactgctgg acatgctgcc agtgtaggac gagttgatcc agaagaaatg
    10741 tactatctga tgagtagagg attgcataaa gaagaagcag agcgcttagt gattcgagga
    10801 ttcctcggtt ctgtcttaac agcaatccct gtagaacaag ttcggaaaga attagtcgaa
    10861 gtaatcgaag ggaagttgaa tggatgatcg atgctaaaaa gctacgcaat gattttccta
    10921 tcttatttca agacgtcaat gatgaacctt tagtttatct ggataatgca gcgacgaccc
    10981 aaaagccaaa acaagtactc caggcattag cgtactatta cgaacacgat aacgccaatg
    11041 ttcatcgcgg tgtccatacg ttagcagaac gcgcgaccca tgattatgaa caagcaagag
    11101 aaaaagtacg ggcgttcatc catgcaaaag aaacagcaga agtgctgttt actcgtggta
    11161 cgacgacaag cttgaattgg gtagccagaa ccttcggcga ccgctatatc aaagcaggag
    11221 acgagatagt gctctcttac atggaacatc attctaatgt tatcccgtgg cagcagttgg
    11281 caaaacgaac aggtgctgtc ttgaaatata tcgaactaac agaagaaggc ttcctggata
    11341 tggaggatgc agcgaaaaag attacggaca aaaccaaaat cgtctccatt gctcatgtat
    11401 ccaatgtctt aggtgtcttc aatcctgttc aagaattagc tgaacttgtc catgaaaacg
    11461 gcggggtcat cgtagtagat ggtgctcaat ctgccccgca catggccatt gatgtccaag
    11521 cactagactg tgatttcttt gctttcagcg gacacaaaat gtgcggacca acaggtattg
    11581 gtgttttata tggtaaacga aaatggttag aagaaatgga acctgttgaa tttggtggcg
    11641 aaatgatcga ttttgtcgaa ttatacgaca gtacatggaa agaactacct tggaaattcg
    11701 aagcagggac accaaatatc gccggcgcta tcgcattagg ccatgcaatc gattatttgc
    11761 aaaaactcgg tatggacaat atccatcgat atgaagaaga actagccgct tatgtgttgc
    11821 caaaattaca agcaattgat ggattgactg tttatggtcc acaagacccg aattttcgga
    11881 caggagtcgt tgcattcaat ttggatgggt tacatcccca tgatgtcgcg acagctttag
    11941 acatggaagg ggtagccgtc agagcaggtc atcattgtgc gcaaccgcta ttgaagtacc
    12001 ttgaagtatc agcgactgct cgcgcgagct tttatttcta caacacaacg caagacgccg
    12061 accgtttagt tgaagcaatc atggcaacaa aggagttttt ccaacatggg actatctaaa
    12121 ttagacaatt tataccgtca agtgatcttg gatcattctt cccatccgca tcatcgtgga
    12181 agcttgactg actcgacaag caagatcgaa ttgaacaacc ccacatgtgg agatgtgatc
    12241 gaattgcaag tcgatgtaaa agacggaatc atcaaaaata tcgcctttga cggcagtggc
    12301 tgctccatca gtacggcaag tgcctcgatg atgacagacg ccgtcatcgg aaaatcaata
    12361 gaagaagcag aacatttaac tgtagacttt ctacagcttg tccaaggaaa agaagtcaaa
    12421 gatcccgacc aattaggcga tgctgctatg cttggtggtg tagctaaatt tcccgctcgg
    12481 atcaaatgtg cgacacttgc ctggaaagca ctaggaaaag caatggaaaa cgatggtacc
    12541 gcagctttcc atcattacca caaggaagag gagtgagaac atgggcgtac cagaattaga
    12601 agaatataaa ttcgggtttc acgatgatgt cgaaccggtt ttcagtacag gagaaggctt
    12661 gacagaagaa gtgatccgtg agatgtcaag aatcaaaggc gaaccagaat ggatgcttga
    12721 attccgtctg aaatctctag aaacatttaa caaaatgcca atgcaaacat ggggccccga
    12781 cctttcagac atcgatttcg atgccatcaa atattaccaa aaaccaagtg acaaacccgc
    12841 tcgtgactgg gaagacgtac cagaaaaaat caaagataca tttgaaaaga ttggtatacc
    12901 agaagctgaa cgagcttatc tagccggtgc ttccgcacaa tatgaatcag aagtcgtgta
    12961 ccataatatg aaagatgaat tcgaaaagtt aggaatcgtc tttactgaca ctgactctgc
    13021 tttgaaagaa taccctgaat tattcaaaga gtacttttca aaacttgtac cgccaaccga
    13081 caacaaatta gcagcgctga attcagccgt atggtcaggt gggaccttta tttacgtgcc
    13141 aaaaggcgtc aaagtcgatg ttccattaca aacgtacttc cggatcaatg cggaaaacac
    13201 ggggcaattc gaacgtacgc tgatcattgt tgacgaagga gcaagcatcc actatgtcga
    13261 aggttgtacg gcacctactt attcaagtaa cagcctgcat gccgccatcg tagaaatctt
    13321 tacaagaaaa gatgcgtatt gccgttacac aacgatccaa aactggtcag acaatgtgta
    13381 caacttagta accaaacgag caaaagcata cgaaggcgca accgttgaat ggatcgacgg
    13441 aaacctaggt gcaaaaacaa cgatgaaata cccaagtgtt tacttagatg gaaaaggtgc
    13501 acgaggcacc atgctctcca tcgcctttgc aggagcaaac caaatccaag atacgggtgc
    13561 aaaaatgatc cacaatgcac caaatacatc tagctctatc gtctctaaat caatttcaaa
    13621 agacggcgga gaagtaaact atcgaggaca agtaaccttt gccaaaaaca gtgcgggttc
    13681 gatctctcat atcgaatgtg acacgatcat catggacgaa tggtcgaaat ccgatacgat
    13741 cccattcaat gagatccaca acagccaagt ctctttagaa cacgaagcca aagtctcaaa
    13801 aatctcagaa gaacaactct actatctgat gagccgaggc ctgaccgaat ctgaagcaac
    13861 tgaaatgatc gtcatgggct ttgttgaacc attcaccaaa gaacttccaa tggaatatgc
    13921 agtcgaactc aatcgattga tcagttatga gatggaaggg tctgtaggtt aataactatt
    13981 tcattgctcg aaacgttgat attaaagcgt ttcgagcgtt tttttatttg tattttaatg
    14041 gttggctacg tttttggcta cgtttggaat tattcgccca taaattttgc aaatcggtca
    14101 ccagttttct taacagattg tggtgtgaca tgagcataga tattcatggt agttttaata
    14161 tctttatgac ctaatcgttc ctgtacttct tttatcgacg caccactttc aaacaataag
    14221 ctacagtggg tatgcctaaa tccatgtgga gtaatttgag gctccatcgg tgtctttttg
    14281 taaatccagt ctaaccaatc gtttactact tgggggtagt acaacttgtt tgtgtttgta
    14341 gtgaaaagaa actgttttgg tgaattcgtg ttatagccat ataagatcat tattttcatt
    14401 tgttcttgtt gccaaatacg cagttgttta agtgtaaaat catcaagctg aatcgttctt
    14461 gatgaatttt tagttttagg tacttgtaga actacttgat taaactcgtc ttgagcgata
    14521 gttttaccaa ttgttattgt tttattgaaa tagtctatat cttcccattg aagcgccaat
    14581 gcttcgcttt tacgcattcc tgtataagct aataaacgga aaaaagtgta cagtttaact
    14641 gaattatttt ctttagtatt ctgtaaaaac agttgtaatt gatctttcgt gtaaaacttc
    14701 aagggttgtt cttcttcaat ttttcttgga agcaatgttt tagacatagg attatcctta
    14761 cagacttcca ttgctactcc aaatttaaat atttgagcag ttgtttttct caagaaacca
    14821 tattgtttta atgttttgtg ccattcattc acctgttttt ggcaatagct aacacttatt
    14881 ttatccaatc gtaattcccc aaaagcaggt aatatatggt ttttgcaaaa acgttgagca
    14941 acggcaacag aagacggttt tactcttgtt ctgtagttat caatccataa ttcatacaac
    15001 tcttgaaaag ttgtaacatt gattttaaac tcttgttttt ctttaaagtc tacaagtagt
    15061 ctattaagtg ctgtttgcgc ctcagctttt gatttgaatc ttctacgctt tgtacgtata
    15121 tcttttccag tcttgggatc tttccctaaa taagtttcaa atccccaata tttttcgcca
    15181 ttttgtaatt tataactaaa aaatgttgcc atttgattct ctccttactt cattattgca
    15241 g
//
LOCUS       DAFLVO010000066        14820 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.066, whole genome shotgun sequence.
ACCESSION   DAFLVO010000066 DAFLVO010000000
VERSION     DAFLVO010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14820
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.066"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(296..1024)
                     /locus_tag="L1U99_002207"
     CDS             complement(296..1024)
                     /locus_tag="L1U99_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="HBN1212739.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(1002..2576)
                     /locus_tag="L1U99_002208"
     CDS             complement(1002..2576)
                     /locus_tag="L1U99_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBN1212740.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            2805..3743
                     /locus_tag="L1U99_002209"
     CDS             2805..3743
                     /locus_tag="L1U99_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1212741.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            3755..4666
                     /locus_tag="L1U99_002210"
     CDS             3755..4666
                     /locus_tag="L1U99_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1212742.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            4690..6162
                     /locus_tag="L1U99_002211"
     CDS             4690..6162
                     /locus_tag="L1U99_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBN1212743.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            6213..6824
                     /locus_tag="L1U99_002212"
     CDS             6213..6824
                     /locus_tag="L1U99_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBN1212744.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            6854..8767
                     /locus_tag="L1U99_002213"
     CDS             6854..8767
                     /locus_tag="L1U99_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HBN1212745.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            8895..11876
                     /locus_tag="L1U99_002214"
     CDS             8895..11876
                     /locus_tag="L1U99_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 42"
                     /protein_id="HBN1212746.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            11873..13534
                     /locus_tag="L1U99_002215"
     CDS             11873..13534
                     /locus_tag="L1U99_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HBN1212747.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            13574..14506
                     /locus_tag="L1U99_002216"
     CDS             13574..14506
                     /locus_tag="L1U99_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HBN1212748.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
BASE COUNT         4818 a         2333 c         2979 g         4690 t
ORIGIN      
        1 atttaaataa ctacatccat ttattctatc ttctaaaata gcctttttca tttcagttaa
       61 atagttcagc gccatttttg cactcgactt gcatagtagt tttttccata ttcctcaacc
      121 tcagcggggg ttgaagacat aaggaaaatc ctatgcgtta tgctcaactg gatctgatta
      181 aatattctaa tgtatttttc tctaccatca ttaaatggtt aatagccaaa aatcaccact
      241 tttcaatggc tccttgttgt ataagtataa ctagaagatg aacacgtctg agaaattata
      301 gaagcttttt acggtaatta ctggggctgt gtccagtagt ttttttgaag agaacagaaa
      361 aatagctcac gtgatctatt cctacttttt gactaatttc atcaatagat aagaatgtgt
      421 ctttcagtag agcacttgct cttttgattc gaaagtctag caagtaatca tgaaaggaat
      481 aacctgtttc ttttttgaag gcccgtccta aataagcggg atggtaatgg aattgtgtag
      541 ctacatcttt gagcgtaagc ttttcactat aattgttttg aacgtaatca atcacttgtt
      601 gaattgactc attaaaagaa tcatcagtta gagagttttg attagctgct gatttacgca
      661 ttttttcttc ttgtactaac ttaactaaat aaggaaaatc aatgggtttc gttatgtaac
      721 ttttaataga taaatcaatc cccttttttg catactgaaa attttggtgg gcactaatga
      781 caatactagt aaagtagcga ttggatgttt gttgcaaaga ttcgattaat tcgagtccag
      841 aaattttccc catcgtaata tctgtgataa gtaaatcaaa gcgctggttt tgcaggtttt
      901 taaatgcttc gtctccgtct gtgtagcagt gatcgataat gatgtcgggg actttcttca
      961 aaagataatg ccttatgcct tctacaattg tacaatcatc gtcaacaatt gcaattctca
     1021 acatgcatat tccccccttt ttgtattttg atagtaatcg ttgttccgac gtgtagttgg
     1081 ctttctataa caaaacgtgt atctccagga tagagatgct ttatacgtcg aaaagaattt
     1141 gagatgccga tattctcact ataaggaata tcatcattaa gtttttgttg aatatgctcc
     1201 agcttgtctt ggtccattcc tttcccattt tcaacgattt ttaacacata atggttggtt
     1261 gtttcagttg catagacagt caaacgattt tccttttttg atgaatcgaa gccgtgttta
     1321 atataatttt caacaaatgg ctgtaaagaa agttttggta acattaattg atcaatatga
     1381 tcaatcagct gatagtcaaa gttatgtcga taacgacgtt gatgtagttg caaggagagg
     1441 tcgatattaa ttaattcctc tttcaaatca attatgtcgg gctgatatgt attattgcga
     1501 tacaacttgc tcaataaata tatactgtcg ctgatttctt cgtcatcatt caatatggca
     1561 gtcattcgaa taaattccaa attattaaat agaaaatgag gctcgatttg atattgaagt
     1621 gctgcatact ttgcttcttg cttcaaccaa ttattttcat aaagtgtttt ttgatatgta
     1681 gcattatcta aataaaactg attgatatgc atagcgattt ctttcaaatc accgactttg
     1741 ttttcgatat tgattgactt gtagtctcct gtagatgaat gatttaagga agtaatgatt
     1801 tcctgatact gctggatata gttacgaaaa cttctattta ataattgatg aatagcaaga
     1861 ataaacaaac tcattaataa gaaaatcatg attgccagac ctaataaggt ttgtgacgaa
     1921 taatttggat tttcatatac ttgtaatgtg tggttaccga tagctatctg ttgcgttttt
     1981 ttccatttag aaggcgagat gtcttcagat aaattgacgg aatcaatacc attagacaaa
     2041 gaataattgt aatgtgttgg aaagagactc ttttttagcg cgttgatcga aacgtctaga
     2101 atcaatgtag catcgggcat gtcctcacta atgaaactta atgaacgaat aaaagaaatt
     2161 ttttcgtttt ttgtaggtgc gtaggcactt aagtattttt cgtaatctaa tgagatagat
     2221 atatttttaa cttcatcatc ttgcacaagt ttttttaagt tatctactaa ataggtaggg
     2281 gagcgatcct ttgacaaaat atcttccatg tattcagcag gtgatgagag gtagtagtca
     2341 ttaaggtttt cttggaaatc ataattttga tagatctctg tcacgatacc ggagagaata
     2401 cgattatatg tttccatata gtgggtgatt tgctgaatgt tttgcaggtt ttgatttttt
     2461 tctttttcaa tcacattgat ataggaaaag aacaatgtga aacaggcaag taaagtaata
     2521 aaaaaaatca atatgtatgt aaaacgcata ataacttttg ataaatcgtt tttcattcaa
     2581 agtcctcatt ttgataatct ctaattttat gaatcattat agcacatatt acaagtgatg
     2641 taaacgcttt gcaaacaggg ctacttatga ttgtgaatac agtttccgtt taaaaactat
     2701 tctattgtag aggtttaata aactaaaaat aatgtataaa aaattaatgt aagcgattaa
     2761 ccaagtgggt ataatcaagg aaacgctgag agaggagaga caaaatgaag ctaaagaaag
     2821 ggttattagg aaatctaaaa aaaaaccgag cattgtttat tatgctttta ccaggtgcgt
     2881 tatggttatt tatattttgc tatataccaa tgtttggagt tgtaatcgct tttaaagatt
     2941 tcagaatttc atcaagggga ttctttacaa gtttgttcaa cagtccttgg gttggctggg
     3001 aaaatttcaa atatctcttt gcttcgcaag atgcttggat cattactcgc aatacggttg
     3061 tttataacgt tgtaggtatt ttgctaagta ctttttgtac agtgtcatta gcaatcattc
     3121 tgagccaaat ggcgaacaaa cggttattga aaaagatgca gacatttatg atttttccta
     3181 attttttatc atgggtagtc atcagttact ttgtttacgc atttttgagt acggataaag
     3241 gattaattaa tattttacta agcaattttg gtgtggaacc cataaattgg tatagtgaac
     3301 cgaagtactg gccttttatt attgttttta cgagtttatg gaaaggcgta ggctatggat
     3361 ccatcattta ttacgcgtca attatgggga tcgatactag ttattatgaa gctgctttag
     3421 ttgatggtgc cagtaaatgg caacagataa ggaatgtagt cttgccacat ttaagatcga
     3481 ttattgtcat tatgttgatt ttgtctgttg gtagtatttt tcgagctgat tttggattgt
     3541 tttatcaatt gccaagaaat tcgggggctc tttatgatgt gacgaatgta ttagatactt
     3601 atgtctaccg tggattaatg aatagcggag atatcggaat gtctacggca gcgggattat
     3661 atcagtcatc agttggcttt gtcttgattt tgattactaa taagatagtc aacaagttag
     3721 atcctagttc agcactattt taggaggaat caaaatgata tcaaaattaa aacggcagat
     3781 gtacttttcg ctgccagtcg aacggttttt cacaatatta ctaatcttat ttactcttag
     3841 ctgtattttt ccctttattt tcgtaatcgt catttcatta acagatgaaa aagcattaca
     3901 actcaacggt tacgaattat tgccggctca atggagcact gatgcatatc aatacttaat
     3961 acaagatggc ggacagttac ttcggtcatt aggcgttaca attatgatta cagtgattgg
     4021 aacgttgatt actgttttta tgacgggaac ctatgcttat gttttatcaa gagcctcttt
     4081 cccttaccgg aagttcttta ctttttatct tttttttacc atgttatttg cgggagggat
     4141 ggttccttct tacttagtga tgacgaagat gcttggctta aaaaatacaa tttgggcttt
     4201 gattctacct cttgctttta gcccatacaa tgtcattatt ttaaggacat tctttaagaa
     4261 gtcgattcca gaatcgatta tcgaatccgc taaaatggat ggctgtagtg agtttcgagt
     4321 ttttttccaa atcgttttgc ctttagcgat cccaggggtt gcaacaatag gtttattttc
     4381 aagcttaggt tattggaatg actggttcaa cgcattgctg tatattgaca ccaacaaatt
     4441 gattccattg caatatttgt taatgaagat tcaaaattca atggaattct tagcaaataa
     4501 taatgacatt acattagcgc agcaacaagc aattcaaaat agccttcctc aagaatcaac
     4561 acgaatggca atggtcgtag tagctacttt accgattgca attgtttatc cgttcttcca
     4621 aaaatacttt gttcaaggat tgacgatcgg tggagtgaaa gaataaaaaa gaataggaga
     4681 tgttaaaaga tgaaaaagaa catgcagaaa tatttgattg gtggtgcttc tgtactaacc
     4741 cttggcctat taggtgcttg tggtagcagt aatggcgaag caaataatga aacaggaacc
     4801 acaaaagtta cttggtatca ggttggagaa gaacccaaag attttgatga ggtcatgaca
     4861 aaagtcaacg aaaaattaaa ggaagaaatc aatgtagagt tggatatgcg gctgattccg
     4921 gacggggatt atcagcaaaa gcttggtgtg atgatcaatt caggagaaga atatgatatt
     4981 tgtttcgtca atggcacaga ttatgtgaat tatgggaaca aaggtgcttt cattagtctc
     5041 aacgatcatt tggataaaga gttgaaagat tatgcagctg aattgaatga aggatttatt
     5101 gaaggtgggg caattaatgg cgaaacttat ggattgccag tcaataacga tattgccaca
     5161 acggaatatt ggacctttaa taaagatttg gtagatcaat accaattgga tgtagagaat
     5221 gttgaaggtg tagaaacatt ggctccagta ttagaaaagt ttgcagaaaa aaatactgat
     5281 acgaatatta cgccaatcgg tatgacccgt accagtgtct gtattcctta tgacaatatt
     5341 atcggtggtg gtgtaccgct agcggttgca tttgaaggcg atacacaaac agttgttaat
     5401 acttatgaga ctccagaaat gatgacttat ttgaaggcta tgcatgagtt ttataaaaaa
     5461 ggatatattt tgaaagatgc agccactgtt acgacagatc catttcgaat tgatagtaaa
     5521 aactggtttt taggtcgtaa ctcaagtggt tatcaaccat tagcacaaaa aaaattagaa
     5581 gctctagcgg gacatggatt aattttaaaa ccagctggaa aagcttttaa aacgactgga
     5641 tttgcaagag tggcaatgca tgcggtatct gcttcaagta aacatccgga agcagccttg
     5701 aaattgttga attatgtgaa taccaatcaa gaagtagcgg atttaatggt ttatggaatt
     5761 gaaggaaaac actatgatcg caatgaagat ggttcgatta ctttaacaaa ctctgatgat
     5821 tattatcaag gcgcttgggc attggtaaat acttatctag tttcaaaaac ttcaccgatt
     5881 acagaagaaa gtaaaaaact agaagaagaa agtaaaaagt ttcaaaatga agcaccgatg
     5941 tctcctattt taggtttctc ttttgacgct tctgattttc gaacagaaat tgcaagtgta
     6001 caaaatatcg tgtcacaata tgaagtactt ttaagctcgg gaacagttga ccctgaacaa
     6061 tatgtaccag agttgttaga aaaactagaa aaagctggat tggataaaat tcaggcatct
     6121 gctcaagaac aatacgatga atggcgaaaa tctaacaaat aattttttac taaatgaaaa
     6181 gaatagacta agcagttagt ggggggattc aaatgaacga aaacaaatgg accaaaggat
     6241 ttaattgggt ttttcaattg ttgttactaa actttactta ttttatacta atttgtttag
     6301 gatttggaat tttaggtttt ttccctgcta cgatagcttt gattgctggc gttgtgaatc
     6361 gaaaaaaata tggcttgcaa gagtctgtga agttcatgag taaaatctat aagaaaaatt
     6421 ttgttagata taatctatat tgctggtcag caactttgtt gttggccggc aatattacta
     6481 cgatctggct ttgttggcag caaagcgcac cattgtttta tttattaagt acattattat
     6541 cggtaattac actgttccta gtctttgcaa tgttgaattg ggtcgtgatc aaaagtcttg
     6601 ggttgtggat gatgggagac cgactgattg actatttgct tttcacagca acgatgttgc
     6661 caacggtagt catgcaaggc ttggtgcttg gaatttattt ccgaatattg atgattttgc
     6721 ctgtgatttt tctgtttggc ggaacagctg taacggtaat attgattagt aaattaactg
     6781 aaagagcgtt agcaaagttg ccttgtcaga tacaatcgca ctaatttttt cacaaaaagg
     6841 agtatttctt tctatgaagt taactgataa acaagtagct aatatagcct ttatccagca
     6901 acttgagatt ccattgacac aaaaagatga agaacaaata gacttgattt ttactgacac
     6961 aaaggctaat gtgcgacaaa tcaagattac taaaaatgag cagcaacgaa tttgcttgtc
     7021 ttattcacat gaagacttgc tgtatcgagg attgtttatc tgccttccac gttttttagc
     7081 tcaaggagga gagatgccat acattgaaga aacctcgatc attgagacca gttattcatt
     7141 agatgcttct cgtaatggcg tgatgaataa agagactcta aaaaaattca tttcttactt
     7201 agcgttgatg gggtacaaca cattgtatat ttacacagaa gatacctatg aagtagaaga
     7261 ccttccatat tttggttacc ttcgcggagc gtatacaaaa gaagaagtga atgaaattgt
     7321 tgaatttgct tctggttttg gcatagaagt agttccatcg atccagaccc ttgctcactt
     7381 gacccaattt ttgaagtggt atgctcaaca agaactgatg gatgatcaaa atactctact
     7441 gatcggtgaa gaaaaggttt atgcggcaat cgaaaagatg attattgcct gcaaagaaat
     7501 gtatcagaca gagcgtattc atttgggaat ggatgaagcc tatcaagcag gtctgggacg
     7561 atatttaagc ctgtatgggt attgtgatcg gacaacttta atgattcaac atatggaccg
     7621 tgtgttatca attgttgata aatataagat gaaaccaatg atttggagtg atttcattta
     7681 taagctatta gatgaaaccg gtaaagatag gtattacaat cctgatttta aactcaaagc
     7741 attagcagct aaaggattac cagcaggatt aacctatgtt cattgggact atggttcaga
     7801 tgaagtttcc tcctatgaga aagtaattga taaccatttg aaattttgtg acattgatca
     7861 ttacgtttta gctagtggtg cccatatctg ggggagacta gccccgaatc atgggaaaac
     7921 agaagcaatt gtttctgcag ctgtaaaagc ttctaaaaat aaaggtgtac gttctgtgat
     7981 gttaactact tggggagatg aagggcagga aacagagcat tggcattcct taattggggc
     8041 attaaaatta gcagattatg tctattctga agaagagtgg aatgattttg aggaaatcta
     8101 cgatcgttta ttaggaacag gtagttatca attaatgtcc gaattacgat atttcgatga
     8161 agtggatacc attacaaata acaacttaca aatggcttcc gtgagtaaac tgctactttg
     8221 gcaagatccg ttagttggta tatatgactt tcatgtagcc gctcataaca aaattgccac
     8281 tagaacaatt ggtacttatt atcatgagtt agctcagaaa ttagatatga ataaaaattg
     8341 gaatccaaaa caaccaattt taacaactat tcgtcaacga tatatacttt tagctgaaat
     8401 tttagcacaa aaggcagaac taggcatcta tttacaacac tgctgtctgg tagaagacct
     8461 tgcaggatta atggaattag cgaatcggtg tgaagcacta gccaatcgag taaatgaatt
     8521 ggcatctatt catgaaataa tttggtatca aacatacaaa acctatggtt gggaagtatt
     8581 agaacaacga tatgctgcat tagctcatcg tctgaaaacc gttgcgcgtc gtattaaaaa
     8641 tcatcttcag gggcaagatg ccctagagga gcttttggaa gaacgattac cgttttgtca
     8701 atatcaagtg ccgcttgaaa tttctggctt taattatcgg caaagctcgg tgtcaggcta
     8761 caattaacga aggaatcttc ccgttgaacg gaccacttgc tcatctaatg ggaaagtggt
     8821 tcgttttcta ttcataagta gcttaccact aactctttta ttaagaagag aaaaaaagta
     8881 ggaagtgaga aaatatgtta tcggactatt atcaaaatct gtcagttata agtgtcaata
     8941 cagaaccatt acgtaattat tatattcctt atgcaagtaa agaagaagca aaacaagagt
     9001 tagaaaggga aaaaacgagc cagtttatcg atctcaatgg tacatgggat tttcagtatt
     9061 atccttctgt ccaacagtta ccggaaaatt tttttcaaga ggcctttact gaaagctatg
     9121 atagaatttc tgttcctgga gtttggcaaa cagagggatt tgacttacct cagtatatca
     9181 atgtatctta tccaattcct tttgatccgc cttatgtacc taatgatacc ccttgtggtg
     9241 tatatcggcg tcagtttcaa attgagcaaa cagatgcacg cttttactta aatctagaag
     9301 gagcagatag taattgtttt gtttggataa atagaaactt tgtaggctat gaccaagtga
     9361 gtcatagtac atctgaattt gatgtgacca agtatttaca ggttggggtt aatgaaattc
     9421 aaattctagt gatgaagtgg tgtgatggta cctactttga agatcaggat aagtggcgaa
     9481 tgagcggtct atttcgtcca gtgtatcttc ttcaacgacc aactatgcat ctgacaagtt
     9541 atcaactacg gacgttgact gatcctaaaa aaggaagcgg aacattaatg gtttcttttc
     9601 aacgatttac tcctattgaa gtatcgttac ctatttctta cgaattattc catcctgatg
     9661 gacgtctcat agcgaaaggg gagtgttact cggaacaaca aataaatttg gatgttgaag
     9721 attgcctttt ttggacagca gaaacgccta aattatatac attactttta acatgtaatg
     9781 gtgaatattt taaagaaaaa gttggctttc gagcactgac gatcaagaat cgtaagttat
     9841 tgctgaacgg aacacctatt aaattatatg gagtcaacta tcatgacgtg aatcagcaag
     9901 gcacgccagt gatgacccga gagcagttac gtgcagattt gttattaatg aaaaaattaa
     9961 atgtgaatac tgtacgaacg gcacattacc ctaaatcacc agatttttat gaattggcgg
    10021 atgagattgg tctgtatgta atcaatgaag cagatttgga gtgtcatggt gtggttaatc
    10081 tatatgatac tgaagcgaat tatcaactaa ttgctaatga tccgacattc gaaaagccga
    10141 ttatggaccg agtgatccgt tctattcttc cttatcaaaa tcgaagctct atcattatgt
    10201 ggtctatggg gaatgaatct ggttatggag taaattttga aaaagctcaa gctttagcac
    10261 ggaaattgga tgattcacgg ttgattcata atgaacgctc gattgaacca gttattgacc
    10321 aagtgaatga ttttagtaac ttggatgtta ttagtcaaat gtatccccca ctggaagatg
    10381 ttcatcgtca ttgtcaaaga agtgatactg aaaaaccttt ttttatgtgt gaatatagcc
    10441 acgctatggg caacggtcct ggagatctta aaacgtactt cgatttgatt caacagtatg
    10501 attcctttct tggcggttgt gtctgggagt ggactgatca tgcaatcaat agaggaactt
    10561 tagaaacgcc atcttattta tacggtggtg attttggtga aaaatatcac gacggcaatt
    10621 tttgcgtaga tggtttattg accccagatc ggcaattaac agtaggtgca ttggagtacc
    10681 gtaatattca ttcgcctatt caactgattg ctgtagatga ggagctgcaa gaagtaacct
    10741 tgagcaatat aactgctttt acagccggtt cagcatttaa cctttctctt gaatggtata
    10801 tagatggaaa aaaaacagtt tatgaagtaa tgaatccttt catacttgag cctggcaaaa
    10861 gttgttcatt gcccatcaca gtacctacaa cgattcatgg tgctcatacg gttgctgttt
    10921 cgctatctgt ttataaaaat gatgagcttt atggacagca acagctcttt cttaaaaaag
    10981 aaaaaatgag attgccaaga actgctcatc ataatgatgc accacaaatt tcagtaaaag
    11041 gcacagagct gataatcaaa ggagaatcct ttatttatat atatcaatta gcaaaagctg
    11101 cgttcacttc tgtaaagatc aatcaaaagg aacttttgga acgtcctact caattttcaa
    11161 tttggcgtgc accaacggat aatgatcgta acttagtaaa caaatggaaa gcagctggat
    11221 atgctgaaat gtctttagaa atcagaaaaa aagactggaa attcgtagat gatcatctcc
    11281 tgatcgaaac gtcttatcga ggagttattc caggattaca gccaattttt acaatgcaca
    11341 tacagttgaa aataaatggt gcaggcgtaa tcaaccaaaa agtatcagtg gagaaaaatc
    11401 cgatttttcc agatttccct cgctttggga tggactggcc gttgaatgat actttttcga
    11461 aggtttctta ttgtggctat gggccgtatg aaagttatcc tgataagcac tatgctgcga
    11521 tgtttggtat ttatgagatg gagattgagg aatttgatca gccatatatc aaaccacaag
    11581 aatatggtaa ccgctggcaa tgtgattggg tatcaatcaa aaatcatcaa ggatctacca
    11641 tgacggttta tggaaactct aatttttctg ctctgcctta tagtcaagct caattaaccg
    11701 aaaagtcaca ccattatgaa ttaataaaag aaaatagaac ttggttcaat ttaagttata
    11761 aacaaaatgg tatcggctca cacagttgcg gtccttattt agaagatcgt ttccgtttta
    11821 tggaagatac ttttgactgg aatatagtga ttactttcaa aggagaaaat agatgaaaga
    11881 aacaaagatc aatcaagtca aaaaaaaatt atctcgttat caagaagttg tttatcgaaa
    11941 ccattgctta aaatggtcaa aaaataagct gaatgttcgt tttaatggat tattttatcg
    12001 tttcgaacag ttagaagaag tctggaaacc ggtaacgaat ttccaatcat gtcctgtaca
    12061 gctcataaat gatccaaaag aaacatacga tttatgtata acacaccttt ataaccagca
    12121 tttgaaaaat gacggatttt atttaaaggt tactaatgac aatcaactta cgattgaatc
    12181 agcaaacctt cgagggtttc aatatgctat ggaagcctta ttagagagtt ttttttcggt
    12241 aggagatcaa ttattattac cggaattgat tctgaaacat gaaccatcag tgaaaattcg
    12301 aggaatcatt gaagggtttt atggtatccc ctggacacat gaaatgcgcc tctctctttt
    12361 ttcatatatg aaagataacc aattgaatac ttttatgtat gcccctaaag atgatgaatt
    12421 attacgtaaa aaatggcgtg aactctacga tgcgcaagaa ttagacaaat ttaaggagct
    12481 tttatctgct gctgaggcta gcaatatcga tttttggtac ttaattagtc ctggaaatga
    12541 tattgatatt acgtgtgaag aagacattca agttcttctg aaaaagttag aacaactgat
    12601 tgagcttggc gtatttcaat ttggtctatt aatggatgat attgactatc aattaaaagg
    12661 tgctgctaaa cgccgttttc gagagccagc attcgctcat gcctatttag tgaatcgagt
    12721 agaggaatat cttagcactc ggttgtccaa tcatgaatta gtcatttgtc ctacagaata
    12781 tgataatcgt catggttctc gctatttagc aacgttaagt caagaaatac cagaacaatt
    12841 accgttcttt tggactggcc caagcacgtt agcggcgtca atttctacag aagagctgca
    12901 ggaaatggct tctgtctatc aacggccgat gctgatttgg gataatattc cggtaaatga
    12961 ttatttagag gataaagaac tattgttcat gagtccatat gagaatcgaa caccgaatct
    13021 ttctaaggag agataccagg ttacaggagt agtttcgaat ccaatggctc aattagaagc
    13081 ttcaaagttt acgatcaata gtatggctaa ttacttatgg aactgtgagc gttttgatcc
    13141 tttggaaact tggacgtcag tcgttgaaaa agtagttgga agtaaactac aaccagctta
    13201 tcttacctta accaatgctt ttccaaatca ttacacaagc agtctgcttt cagatgaaga
    13261 attactgcta gccaaagacc cagaatgggt cacaaaagaa atggctgctt tagtccaagc
    13321 agtaaaatgg atccagcaag aacaacatac atctagattg agaacagaat tggagccttg
    13381 gttacaagca atcacagaaa gttggacttt ctggcaagaa tggcaattaa aaaaagatcc
    13441 aaaagaagca gaagaatggt tggctaagaa aaaaacacac cgcataggac gtgatttagt
    13501 aactgcccat ttagagcaaa ttatcaaaag ttagatatct taaaaaataa aaagcaagaa
    13561 aaaggagaac aaaatggtca agagattaat tagtgcaaac tacagtgatg tcaagaaaat
    13621 gacgtcaaaa gagttgaagc aatccatcaa agcgagtgaa ggacgggtga ttgtttgtga
    13681 aacggttgct aatactcttc cacaatctgg agaaattacg aatgcagaag ttgcgtcagc
    13741 atttggtgca gatttgattc ttttaaatgg tttcgattgt tatcgtcctg cagtttttgg
    13801 actaccaaat gtgacgattg agaaggtttt tgatctacag caaacgattg aaaacccgat
    13861 tcctaaatta aaagaactag tcggtcgtcc tgtgggaatt aatttagaac ccattgcccc
    13921 taaaacaaat atgatgagtg agaaagtaga aatcagccaa ggaagagcaa gctctgttga
    13981 aacgatacaa aaagcagaag aactaggagt cgattttatt tgctttaccg gtaatccagg
    14041 cactggagta accaatttag aaattactaa atccgtaaaa atggcaaaaa agtatttttc
    14101 gggattgatt attgctggga aaatgcatag cgccggctca gaagagccag ttgtgaataa
    14161 agaggcgatt atttcttatg cggaagcagg cgcagatatt ttactagttc cttcagtagg
    14221 gtctatccca ggctttttag agcaagacct aattgaagcg gttcggttgg caaaaaaata
    14281 tgatttgtta acgatgtctg caatcggtac tagtcaggaa agtgcccgac cagaaacatt
    14341 gcggcaatta gccattatga ataaaagttg tggtgttgat ttacaacata ttggagatgc
    14401 tggatacggg ggattggcac cagcagaaaa tattttcgaa acctcggttg caattagagg
    14461 aatgcgacat accatcaact gcgttagccg ctcgatcaat cgctaacaaa attaaataaa
    14521 aaatggttaa attgattatt taagtgggaa catacttgag atatcagcta acttctgtca
    14581 ctttaaaaaa gggactgtga cagaagtgaa aatagacaaa aaatatccga acaagagact
    14641 aggatagcag aaaaactatc gttttgcaac gaggaccaac tggaccgtag gagcaattct
    14701 cttattgttc ggatatttcg cttgttcaag gacttatgtc tgtagtgccc ttttttggta
    14761 ggaaaaatgg tagggaacca tatcattttt aatgaaaatc aagcatttca aaagttgaaa
//
LOCUS       DAFLVO010000067        14621 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.067, whole genome shotgun sequence.
ACCESSION   DAFLVO010000067 DAFLVO010000000
VERSION     DAFLVO010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14621
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.067"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            262..1371
                     /locus_tag="L1U99_002217"
     CDS             262..1371
                     /locus_tag="L1U99_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBN1212749.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASASTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            1454..2350
                     /locus_tag="L1U99_002218"
                     /pseudo
     CDS             1454..2350
                     /locus_tag="L1U99_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648409.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            2366..3190
                     /locus_tag="L1U99_002219"
     CDS             2366..3190
                     /locus_tag="L1U99_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1212750.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            3222..4532
                     /locus_tag="L1U99_002220"
     CDS             3222..4532
                     /locus_tag="L1U99_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HBN1212751.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            4680..5939
                     /locus_tag="L1U99_002221"
     CDS             4680..5939
                     /locus_tag="L1U99_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBN1212752.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            5949..6821
                     /locus_tag="L1U99_002222"
     CDS             5949..6821
                     /locus_tag="L1U99_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1212753.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            6833..7663
                     /locus_tag="L1U99_002223"
     CDS             6833..7663
                     /locus_tag="L1U99_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1212754.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            7703..9886
                     /locus_tag="L1U99_002224"
     CDS             7703..9886
                     /locus_tag="L1U99_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBN1212755.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            9947..11167
                     /locus_tag="L1U99_002225"
     CDS             9947..11167
                     /locus_tag="L1U99_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HBN1212756.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            11164..12624
                     /gene="gtfA"
                     /locus_tag="L1U99_002226"
     CDS             11164..12624
                     /gene="gtfA"
                     /locus_tag="L1U99_002226"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HBN1212757.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            12701..13807
                     /locus_tag="L1U99_002227"
                     /pseudo
     CDS             12701..13807
                     /locus_tag="L1U99_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            14129..14338
                     /locus_tag="L1U99_002228"
     CDS             14129..14338
                     /locus_tag="L1U99_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBN1212758.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMASKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            14331..14480
                     /locus_tag="L1U99_002229"
     CDS             14331..14480
                     /locus_tag="L1U99_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HBN1212759.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
BASE COUNT         4973 a         2219 c         2878 g         4551 t
ORIGIN      
        1 ttttgtttac taatattttt agtaaaaaat ctcgacaaaa cattaagtaa acagttatgg
       61 tgttgttaac aaaaagaaaa cgcattcaaa acaggaggaa ttaagatgaa acatttcaaa
      121 aaaatagctt taacagggat agctgtttta actgggacat tactcgcagc atgtggtggg
      181 ggagatagta attctaaaga cgggcaagta actttaagct atgcgagttg agatactgac
      241 caagctccag gactaagaaa aatgttagat gaatttgaaa aacaaaatcc tgatatcaaa
      301 gtagaaatgg agacaacgcc ttgggatcaa tattgggtta aattagaagc tgcaacaacg
      361 ggaggtaata tgccagatgt agtaaccatg cactctagcg aatcctataa atatatgtca
      421 cagaatgctt tgatgggact tgatgatgtt atcaaagaaa atgatattga catgggaaac
      481 tttactgaag gaattgctga tttctatacg cttgaagacg aactatacgc aatccctaaa
      541 gatgcttctg tagtggggct atggtacaac aaagaattat ttgataatgc aggtgtcgat
      601 tatccagatg aaacatggac atgggaaaca ctcagacaag ctgcaattga tttaacagat
      661 gaatcaaaag gcatctatgg ttttgcatca catattggaa cagagactgg ctactggcca
      721 tttatttatc aaaatggggg agaagtattt gccgatgaca atacaaaatc aggtttgaat
      781 accccagaag cacaagaagc tttagctttt tatcgagata ttgcacttgt tgatcatgct
      841 tcaccaacaa ttacagaatt acaagatcct gataagttaa gtcgttttca atcaggtaga
      901 ttagcaatga tgattgaagg aaactggttt gcaccgggat ttttgaaaaa tgactatcta
      961 gttgaaaatg ttgcttctgc cgtgttacct aagggaaaag ttaatgcaac aattacaaat
     1021 ggacttggtt gggctgccag tgcgagtaca aaatacccag aagaagtgaa aaaactaatg
     1081 gcatttttag ctagtgagga cgccaataaa atccaagcgg aaacgggggc atcaatccca
     1141 gcactaaaag gctttgaaga cgagtgggct gcttcttcag atacaattga tttgagtgct
     1201 tttggaaaaa tgttggagta tggagtccct cgtccataca ataaagatgg attacgagct
     1261 gaacaagcag aagttcaaat tattaaccgt attctgtctg gtgaagtaac tgttgaagat
     1321 ggaaccgctc aaattgaaaa agaagtcaat gcgatattga gcggaaatta aattagttaa
     1381 ttatacaata tacaggcgaa aggattctat ttcgtctgta tattaatgga tgaataccaa
     1441 aaagggggat attatgaaaa atcgaatttt tggaaaatat cgtaaagatc aagtgatatg
     1501 gggctatatt tttatttttc caacggcatt aggattaatt ttattaaata tatggccagc
     1561 aattcaaaca gcaattttaa gttttcaaaa aacggtaggg ttcggtgata ctgaatgggt
     1621 cggattaaga aattaccaaa aaatgtttgc agacggtgaa gtttttcagt ctttattaaa
     1681 cacattaatt tatgcagtgg tttcgatacc tagtattgtt gtattatcct tgttggtggc
     1741 agttttaatg aatagaaaag ttaaaggatt gtcgatttat cggacaattt attttctacc
     1801 agtcgttgct gcaccatccg cagtcgcaat gatttggcgc tggatgttca ataatgatta
     1861 tggactgatt aataacatgt tggctaaaat aggtctcgat ggaccagcat ggttaacgga
     1921 tccatcgatt gcgatttatt ctattatcat tgtaggagtt tggagtgcta ttggttataa
     1981 catggtgtta ttactagccg gcttataaga aattcctaaa gattattatg aagcagcgga
     2041 aattgatggt gctagtccaa tccagcagtt tttcaacatt acgttaccat tagttacacc
     2101 aacattattt tttgtagttg taacaacagt tatcaatgct ttccaagtat ttgatgttat
     2161 ttttatgatg attactccta atagtaccgc catgtttaaa tcacaatcat tagcctattt
     2221 attctataaa cattcattta ttttaaatga caagggatat ggttcggcaa tcgttatgtt
     2281 ccttttagtg attatattaa ttattactgc aattcaaatg aagttgcaga aaaagtgggt
     2341 aaactattaa ggaggctatc aaattatgaa aaataaattt ttttcaaatg cgccaatcca
     2401 tatcatgctt attttaggtg gtattgcaat ggcattacct tttatttgga tgattttaac
     2461 ttcagggaaa acgttggttg aatctaccca aattccacct acaattttcc ctgagaaatt
     2521 tcagctaagt aactatcaac aagtacttga tttattacca ttcatggctt tttatatcaa
     2581 tacattttta atggttgttg gacgagtgat tggctcggtt ttattttcag caatggctgc
     2641 atatgcttgt gcgcgtctaa gttttccagg gaaaaatatc cttttcagct tagtacttat
     2701 tcaaatgatg attcccggtt ccatttttat tactccacag tatttattag cacaaaaatt
     2761 gggtatttta aatacaattc cagcattaat attaccaggg gtagttagtg cgtttggtac
     2821 gtttttatta agacaatttt tcttaggttt acctgatgaa ttggaggaag cggcctattt
     2881 agaaggtgcc aatatttgga cgatcttttt caaaattatg ttgccgcttg ctaaatcagg
     2941 attggttgca cttggaatat tcacagcgtt gtttgcattt aaagatttaa tgtggccatt
     3001 gattgtcaat acttcaattg ataagatgcc tttagctccg ggattagcaa acttacaagg
     3061 acaatatgcc acgaacttcc cacaattaat ggcaggttcg ttattagcaa tttggccaat
     3121 agttgtgata ttcatcgttt tccaaagaaa attcattgaa ggaattgcta caacaggtag
     3181 taaattataa aactattaat tagtgattgg agagtaagta catgacaaaa attacattta
     3241 ttggtgcagg aagtactatt tttgcaaaaa acgtattagg cgatgcgatg ttaactccaa
     3301 gtctacaaga tgcacatatt gcattgtacg atattgatga aaaacgacta aaagaatcaa
     3361 atttaatgct taaaaatatt aataaaaatt cgaatgaaaa tcgtgctgat attgtttctt
     3421 attatgatcg caaagaagcg ttaagagagg ctgattttgt tatcaatgct attcaagtgg
     3481 gtggttataa accttcaaca gtgattgatt ttgatattcc taaaaaatat gggttgcgac
     3541 aaactattgg tgacaccatg gggattggtg ggatttttag aaccctacgg acactaccag
     3601 taatgttaga ctttgctaaa gaaatggaag aagtttgtcc aaatgcttgg ttattgaact
     3661 atacaaatcc gatggcgatg ttaaccatgg gtgttttaaa agcgacgagt attaagactg
     3721 ttggtttatg tcatagcgtt caagtatgcg taccagaatt gtttgagcat ttaggaatag
     3781 ccgatcaata tgacttaaat gactttcaat ggaaaattgc aggcattaat catatggcat
     3841 tcttgttgga aattacaaaa aatggggaag atttctatcc aacaattcgt cagttagctg
     3901 cagaaaaacc aaatccacat ccagattctg tacgttttga attgttgaaa cgttttggtt
     3961 actatattac agaatcaagt gaacacaatg cagaatacca tccatacttt attaaatcaa
     4021 aatacccaga attgattgac gaattaggga ttccgttgga tgaatactta cgtcgttgtg
     4081 aacaacaaat taatgattgg gaaagcatgc gagaggacat tgtaaataat ggggagttaa
     4141 cacatacgag aagccgtgaa tatgcttcat atatcatgga ttctattacg acaggaactc
     4201 cgtcagtgat tgcaggaaat gtcttaaata aaggcttaat cacaaactta ccgacagatg
     4261 tttgtgtgga agtaccttgt ttagtcgata aaaatggcgt gcaaccaacc tatgtcggtg
     4321 aattgccaac acaattagct gctttaaatc ggacgaatat caatgttcaa gaactgacag
     4381 tagaagccgc tttaacacta gataaatcaa aaatttatca agcagcgtat ttagatccac
     4441 atctatcatc tgaattgtct ttaacagata tcaaaaattt agtggatgat ttaatcgaag
     4501 cacatgggga ctatttacct gaatataatt aaaaagaagc tgaaagagta aggaattttc
     4561 aattccttac tcttttctta gttaaattta gtaaaaatat tgacaaaaca cttagtaaac
     4621 agttacatta gtgttaacaa aaagaaaacg cattcaaatt gtataaggag gagcataaaa
     4681 tgaagtggtc taaaaaaatt attttagctt gtatagcact aggagcaacg atctctttga
     4741 ctgcttgtgg aaaaaatcag gaagatgcaa gcggtaaggt agaaatagag ttttttaatc
     4801 aaaaaaaaga aatgactcaa acgattcagg agattgctaa agattttgaa gcaaaaaacc
     4861 ctgatattca tgtaaaagtt gtggatgtac cgaatgctgg tgaagtaatt aaaacacgta
     4921 tgcttgcagg cgatgtacca gatgtcatta atctttatcc tcaaagtata gaattgaaag
     4981 aatgggcgaa agctggttat ttagaggact taaccgaaga accgtattta gagaatatca
     5041 aaaatggata tgcacaacgt tttgctattg aggatcgtgt atatagcata ccattaaccg
     5101 ctaatgtcta tggtttttac tataacaaaa ctgcttttga ggaaatgggg attcaagcac
     5161 cagaaacttg ggcagaattt gaaaaaatag tagctgagat taaagatcaa aacaaagtac
     5221 cgtttgcgat tgcaggagca gaaggctgga ctttaaatgg ttatcaccaa ctagctatag
     5281 cgactgctgc tggtggtgaa gaggaagcga acaatgtttg gcgtttctca gaagttaatg
     5341 gaattaatgc tgaaagcaaa gaaatgcaaa aagattttaa tcgattagat ttgttaagag
     5401 aaccaaaagc tttgcaaaac aactggcaag gtgccggtta taacgataca gtagttactt
     5461 ttacaaaagg tgatgcgttg attatgccga atggttcatg ggcaatgccg atgattcatt
     5521 cacaaaatcc agattttgaa gtaggaactt ttccttttcc agcagatgaa gcaggtcaaa
     5581 gtctaacgat tggcgcagga gacctagcct tatcagtttc tgcaacttct caacataaag
     5641 aagaagccaa acgttttgta gaatatatga caacacctga agcgatgcag aaatattatg
     5701 atgtagatgg tgcaccgtgt gctgttgagg gcgttatcga gaatactcag gattcaccat
     5761 taagtggttt aactgaactt gcttttactg atcgtcattt agtttggtta gccaaagatt
     5821 ggaatagtga aaatgatttt tataccttaa caacaaatta tttacacaat ggcaatcaaa
     5881 aagccatgat taacgcatta aatgctttct ttaatccaat gaaagctgac ggaaggtagg
     5941 aaaataaaat gaaaataaaa gaaattttaa atcgttactg ggcaatcatt tttgtagcaa
     6001 ttccaattat tttgcagatg atttttttct actttccaat ggttcaaggt gctttttaca
     6061 gtttaactaa ttggactggt ctgacttata attttgattt tgtgggtttg aacaattata
     6121 agattctttt ttctgatccg aagtttatca aatcgattgg cttcacttta attgtgacgc
     6181 tttgcatgat tgctggacaa attggttttg gtattttgat tgcgcgggcg ttgaacgcaa
     6241 atattaaagg gaaaacattc tttagagcat ggttcttttt tccagcggtc ttatcgggcg
     6301 tggttgtttc tttagtattt aaacaaattt ttaactatgg tttaccaaaa attggtagta
     6361 tgttaggcat tgaattttta caaaccagtc ttttaggaac aacatgggga gcgatttttg
     6421 cagtaatttt tgttttactt tggcaaggaa ttgccatgcc agtcatcatt ttcttagcgg
     6481 gttttcaaag tattccacaa gaaattattg aagctgctag aatggatggg gcgaatgata
     6541 agcaaatttt ttggaatatt gaaatcacct acttattacc aagtatttca atggtattta
     6601 ttatggcatt aaaaggtggc ttaacagcat ttgatcaaat ttttgcttta actggtggtg
     6661 gaccaagcga tgccacaaca tctttggggt tacttgttta taattatgct tttaaaaaca
     6721 atcagtttgg ttatgcgaat gctattgctt tagtcttatt tatcttaatt gggattgttt
     6781 cactggcaca attaaaatta tcgaaaaaat ttgaaatcta ggaggtttcc caatgaaaac
     6841 atcaaaagaa aaaaatattt ctaaatactt gcttttatta ttagggggct tcatgatttt
     6901 agttccctta gtttcaacgc tattcggttc atttaaaaca acacccgata ttatgaataa
     6961 tttctttcgt tttcctaatc cagcgacttt ggaaaatttc cgaagattgt tagcggatgg
     7021 aattggtcat tacttttgga attcggcaat catcacaatc attgcagtag ttgctgtgac
     7081 agcaattatt cctatggctg cttattcact agcaagaaaa atgactcgtg ggaaagcata
     7141 cggattgatg tatttatttt taattttagg aatttttgtt cctttccaag taattatgat
     7201 tccgattacc gttatgatga gtaaaattgg tttagcaaat atgtggggat taatcttact
     7261 ctatctcact tatgccgtac cacagacact atttttatat gttggtttta ttaaactaaa
     7321 tgtgcctatc agtctggatg aggctgctga aattgatggg gctagtcact ttacaactta
     7381 tttcaaaatt gttttcccaa tgttaaaacc aatgcatgcg acgactatta ttcttaatgc
     7441 tctatggttt tggaatgatt tcatgctacc attattaatt ttaaatcgtg attctaatat
     7501 gtggacacta ccattgtttc aatataatta tacgggacaa tattttaacg actatggtcc
     7561 aagttttgct tcctatacag taggaattgt cacgattaca ctagtttatc ttgctttcca
     7621 aagaagtatt atagctggaa tgagcaatgg agcagtgaaa taaccaataa attattctca
     7681 ttataaagga gttcataaac ttatgattat atttgacaat cacacacaaa catttcattt
     7741 acaaaataaa aaaattagct atctattagg aatcgaagaa aataattatt taacgcatct
     7801 ttattttgga aaaaagatta cgcactattc tggtgggtat cgctaccccc gaacagatcg
     7861 ttccttctca cccaacaatg caaatgcgca agatcgttta ttatctttag acacattacc
     7921 attagaattt ccaggatatg gacatggtga ttttagagaa ccggcgcata atattaaatt
     7981 aggaaacggt agtcgtgtaa atgattttcg ttatgatagc tacgaaattc aaaaaggaaa
     8041 gcccagctta gcgggattgc cagccttata tacggaagat gatgatgaag ctgaaacgct
     8101 gattattcaa ttgaaagacg cgattagtgg attgacttta cagttgttct acacaattta
     8161 tcaaaatcac agtgtaatta ttcgttctac gcaattagta aataatagtg atgaaacagt
     8221 ggagattaac cgcttagcta gtcaatcaat tgattttcca aatcgtccac tcgagttaat
     8281 tcatttaaat ggtacctggg caagagaacg tcaaatgact agagaaaaaa ttcatacagg
     8341 gataaaagta ttagatagta aacgcggatc aagcagccat caacaaaatc cgtttgttgc
     8401 tttagtagat gccaaaacag atgaatttca aggagaggca tatggattta atttagttta
     8461 tagcggtaat cacgaaacgg tgattcaaaa agatccattt gaccaaacac gggtcattat
     8521 gggaattaat tcatttaatt ttggttggca actaaaaact ggcgactcat ttcaaacgcc
     8581 agaagtcgtg atggtttata gtaatgaagg tctgaatacg ttatcacaga cgtatcatga
     8641 attgtataat caccgtttaa ttcgtggaaa ctatcgttta aaagaacgtc ccacgttaat
     8701 caacaactgg gaagcaacgt attttgattt taacgaagaa aaaatcatga atattgtcga
     8761 tgatgcgaag aacttgggca ttgaaatgtt tgttttagat gatggttggt ttggcggtcg
     8821 tgaaaatgac ttcacttcat taggtgattg ggttgaaaca gaaggcaaac ttgcttgtgg
     8881 tttggaaaat ttagccaagc aagtgcatga taacgggatg aaatttggga tttggtttga
     8941 accggaaatg atttctgaag atagtgaact atttcgagca catccagatt gggcattggg
     9001 tattccaggt cgtgaccgct caattagtcg aaatcaatat gttcttgatt tttcaagaca
     9061 agatgttcgt gataatatct atcaacaaat gacggcgatt tttgatcgtg taccgattga
     9121 ttatgtgaag tgggatatga atcgaaatat gacagaagtc tattctgtct tgttggactc
     9181 aacgatgcaa ggtgaagtgg ctcatcgtta tatgttaggg ttatatgaat ttttagaaaa
     9241 gttaacaacg aattatccaa ctattttatt tgaaagttgt tcgggtggag gcggtcgttt
     9301 tgatgcaggt ttcttgtatt acatgccaca aacttggacg agcgacaata ccgatgccgt
     9361 ggctcgtctg aaaattcaat atggaaccag cttagtgtat ccaatttcaa gtatgggtgc
     9421 gcatgtttca gcagtcccaa atcatcaaac aggaagagaa acgagtttaa ctattcgtgg
     9481 caatgctgcg atggctggtg tttttggtta tgagctagat ctaacgcaat taacttctga
     9541 agaaaaagca gaaattaaag aacaagttgc cttttataaa aagcatcgcc aacttttgca
     9601 atatggaact ttttatcgct tggaaagtcc gtttgaaggc aatgatactg catggatgtt
     9661 tgtctcaaaa gaccaaacag aagccatggt cttttatttc cgagtattag cagaagctgc
     9721 gcatccatta gtcacattga aattagcagg attagcagaa gaagcaactt atcaaatgga
     9781 agatgtaaca tttgctggcg atgaattgat gaatctcggt ttttatattg actcagaact
     9841 acatggtgat tatgcgacac aacgctttta tttgaaacag atatagtagc ttgaatttac
     9901 aatataagtg caacaccaaa agagactcat tccaaacgaa gaaaatatgt tttatttaca
     9961 cgcatttact aaaaagcagc ctgatttgaa ttgggaaaat gaagaagtac gtgaagaaat
    10021 ctatgcaatg attaactatt ggttagataa aggactaggc ggatttagaa tcgatgcgat
    10081 attaaacatc aaaaaaaaac tagagtatgg catctttgaa tctgatggag aagatgggtt
    10141 agccttcatt gggccctgga ttcttaatca gtcgggcatt gaagtgtggt taaaagaaat
    10201 gagagagcgg acatttaaac cacataatag tatgacggta gcagaagccg atgttcctaa
    10261 tgaacgttta gatgaatata ttggtgaaga tggctattat tcgatggttt ttgattttag
    10321 ttatacggat attgatgtac ctgaaactgg tgaatggttt aaagatagcc aatggacatg
    10381 gacggatatg cgtaccaata tttttacgaa tcaattagtt acgcaagata aaggttgggg
    10441 cgccttatat ttagaaaacc acgatcaacc acgttcaatt aataaatata ttccagaaga
    10501 atggatcaat gattatagta aaaaaatgtt ggcgacgctt tttatgttac taagaggtac
    10561 cccttttatt tatcaaggac aagaactagg aatgaccaac atagaaatgg catcattaga
    10621 agattttgat gatgtagcta cgcattctca gtataaacgg gcattagaat atggattggc
    10681 accagagcaa gcattgaaag ctgtcaataa acgaagtcgg gataattctc gcacacctat
    10741 gcaatggaat acgcaaaaaa atgccagatt ctcaacttct gataatgtat ggttaaaagt
    10801 aaatcctaat tatccagaac tcaatgcaga agctcagtta accaatcaac agtcggtatt
    10861 caattattat catcaattaa ttaaattaag aaaaaatagt gtatacaaag acgtgctaat
    10921 ctacggacaa tttctaccag tgaaagataa aaatgaacat attttgcttt atgaacgcca
    10981 attagaagat aaaatcgtat tagttatctt aaacgttaca gcaacagaac aagaatatta
    11041 tgtagatgaa cagtaccaac aagtattaat caataattat gaagatgttt tattagatca
    11101 aagtcgaaaa ttgcgtttac gaccgtttga aagtattgta ttagctaatt atggaggaca
    11161 attatgaaaa ttaaaaacga agcaatgctc atcacctatg cagatagttt aggaaaaaac
    11221 atgggcgaat taaaacaagt cttagacaaa catttacaag gtgttattgg tggtgtacat
    11281 ctgttgcctt tttttccatc gacaggtgat cgaggctttg cgccgagtga ttatacgaca
    11341 gttgatccag ctcttggaac atgggaagat gtggaagcat taggtgaaga ttattatttg
    11401 atgtttgatt ttatgattaa tcacatttct cgtgaatcaa aatttttcca agatttcaaa
    11461 aaaaaccatg agcagtcacc atacaaagaa atgtttatcc gtattcatga atttttccca
    11521 gaaaatcgac caacacaaga agatattgat ttaatctaca agcgtaaaga caaagcgccg
    11581 tttcaaacgg tagaatttgc ggatggtacg acagaagagg tttggaatac ctttggggaa
    11641 gaacaaattg atttagatgt gaccaaagaa gttgtgaaag aatttattcg agaaaccatc
    11701 aaagatatgg cgaaccatgg ctgttcttta attcgattag atgcgtttgc ttatgcgatt
    11761 aaaaaattag ataccaatga tttcttcgtg gaaccagata tttgggaact tttagacgaa
    11821 gtgcgtcaag aagcagcgaa atatgacgtc gaattattac cagaaatcca tgagcattat
    11881 tccattcaaa tgaaaattgc caatcatgat tattatatct atgacttcgc cttgccaatg
    11941 gtcactctgt attcacttta tagtggaaaa tcagaacgtt tagccaattg gttgaaaatg
    12001 agtccgatga agcagtttac aacattggat acgcatgatg gaattggtgt tgtggacgct
    12061 cgtgatttat taacagatga agaattggat tacacctctg aggaattgta taaagtcggg
    12121 gcgaatgtga agaaggtcta ttcaagtgcc aattacaata atttagatat ttatcaaatt
    12181 aacagcacct attatagtgc attaggcgat aatgaccgta gctatctgtt agcacgtgcg
    12241 attcaagtat ttgcgccagg gattccacaa atttattacg ttgggttatt agcaggaaaa
    12301 aatgatattg aactgttgga agcaacgaaa gaagggcgta atattaatcg tcattactat
    12361 gatttagccg aaattgaaga agaagtgcaa cggccagtga ttcaacaatt atttgcactt
    12421 ttaaaattta gaaatgaatc tgcggcgttt gatttggatg gaacgattga agtagcaacg
    12481 ccatcagaat cagaaatagt gattacacgt aaaaataaaa acggtagtga tagtgcaaca
    12541 ttaacggcta acttggatac gaaagaattt atcattgagt ctaaagatat aaaaattttc
    12601 actagtgttg cattaaaatt ttaacctatt ccatagaaca aaaaatcctt tatactagca
    12661 cttggatgac ttatccaaga ccaataaaaa ggactcatac atggataagt ataaaacaaa
    12721 tacagcattt aataaatggt tttctgccat aaaattagga aaactttctg tcaactccca
    12781 aaaatgtatt tttgattaca attcgtatcg taaaaaactg tcttttgaag ctgtgctcaa
    12841 gctctttctc tacgcagtta atgaagaaaa agaaagtttg cgtgatttga gtacagctct
    12901 tatcgaccga tcgctccaac tagaaaccga tgtgtcatcg attagtcata cccaattgtc
    12961 tcgagcattt aatgcacttg aacctaaagt gttagaagaa atttttcaac aactgttaga
    13021 aaaagttcaa catcaaatca aaccaaccaa gcgaaatcat ctgtatctga ttgattccag
    13081 tacgttttcg cttagtttaa aacgtcataa gtgggcgact ttccgtcaaa caaaatcagg
    13141 tgtcaagtta cacttaaact attgttatat ggacgatact acgatgtatc caactgattt
    13201 taccttaaca aatgcccatg aacatgatct caatcaacta ccagtattgg tgaatcaacc
    13261 agaggcaact tacgtgtttg atcgtgggta ttaggacttt gaaaagatgg atcagatgca
    13321 ttgggatggc tatttcttcg tcactcggat taaaaaaaac accaaagttc acgtgataga
    13381 tactctggaa acatcgccag aaacagaaat tctacgagac gagctggttc gtttaggatc
    13441 taaaacctat ctaaccgcca atttccgact agtcactgtt caagataaga acggacgtgt
    13501 gtttcaattt atcaccaatc gaatggacgt ctcttcaaaa gaaatctctg atatgtatca
    13561 cgctcgttgg caaatcgaat tgtttttcaa gcacatcaaa caacacatga ccattaaaac
    13621 cttcttttct caaagtgaaa aaggcgtgca gaatcaattg attttaacga tgatttccgc
    13681 tctcctcacg tttctcatca aattggagac gaaaacggaa aaatcagtgt tccaaatcaa
    13741 acgattcttt cgttatttac tgtttcagcc ctttgaatgt tgtctagaaa aattaattcc
    13801 cacatgagaa aaaagaaatt tggctcgtta cttttggttt tcagttgaat aacagataaa
    13861 aaattttctg gaaaaagtca tcctctgcgt cagcacagtt ttttttgact tattttcaga
    13921 ggaaatagtt ttcagaatat tctaaaatgt tttatgcaac actagtgata ttttttagaa
    13981 ttagatttct aatgtgcatt ttttgagtat taaggagcaa gtatacaaag atttataaag
    14041 ctgattaaat ttgaataaaa atatgcagga acgctactat ttttagtagt gttctttttt
    14101 atatttgaat aaaaaatgtg gtggttaaat ggtggttata acaaaaaatg aattaatgaa
    14161 attaggttat gggaagtatc agtctgagag aatcatacga caggcaaaag caattatggc
    14221 ttcaaaaagc tatacctatt acgaaaatag aagattagga ctagtacctg ttgaatctgt
    14281 agaagaagtt ttaggtatga agatagaggt agaggaggat tttcagaatc atggttaatt
    14341 ttaaaaaaga taaaaatggg aaatatcatt ttactgctag tttgggattc gacaaacgaa
    14401 cagggaaaag agtacaaaaa aacgtagagg ggttaaaaca gttaaagaag aaaaaaagcg
    14461 tataccgaac ttgtttctaa ttatggaaaa gaagcagaaa cttctcaaag tactatgttg
    14521 tttgaggagt ttttttataa attattccta ccttattatc aagggaaagt agaagaaaga
    14581 acatataaaa atcggttatc tacaatcaaa aaaacttttc t
//
LOCUS       DAFLVO010000068        14528 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.068, whole genome shotgun sequence.
ACCESSION   DAFLVO010000068 DAFLVO010000000
VERSION     DAFLVO010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.068"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(101..247)
                     /locus_tag="L1U99_002230"
                     /pseudo
     CDS             complement(101..247)
                     /locus_tag="L1U99_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            486..1178
                     /locus_tag="L1U99_002231"
     CDS             486..1178
                     /locus_tag="L1U99_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBN1212760.1"
                     /translation="MNKKIVVSGLIIGGLVLAGIAGKNFADDILLWGGEDNIEQINHN
                     LESLDKALENKEQNISSLNSRLSSNNQELEQAKANVEEYKQKVLTLENDKNQLTIEKT
                     NLENQLSGKNAELQGKQNEINAKIDEINQKIAEINQLNTDWNNRLQTEQNKFNDAQNT
                     VNSLNQQINQLSNEKNTIKNQLQSTEQKLEKAQSENSNLNNYIEKLEKAKSDVEDTAN
                     RSQEIVTEHTGK"
     gene            complement(1460..1532)
                     /locus_tag="L1U99_002232"
     tRNA            complement(1460..1532)
                     /locus_tag="L1U99_002232"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1497..1499),aa:Lys,seq:ctt)
     gene            1913..2482
                     /locus_tag="L1U99_002233"
     CDS             1913..2482
                     /locus_tag="L1U99_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBN1212761.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            2469..3329
                     /locus_tag="L1U99_002234"
     CDS             2469..3329
                     /locus_tag="L1U99_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBN1212762.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            3519..4223
                     /locus_tag="L1U99_002235"
     CDS             3519..4223
                     /locus_tag="L1U99_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1212763.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            4228..6063
                     /gene="walK"
                     /locus_tag="L1U99_002236"
     CDS             4228..6063
                     /gene="walK"
                     /locus_tag="L1U99_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HBN1212764.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            6060..7376
                     /locus_tag="L1U99_002237"
     CDS             6060..7376
                     /locus_tag="L1U99_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212765.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            7377..8246
                     /locus_tag="L1U99_002238"
     CDS             7377..8246
                     /locus_tag="L1U99_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HBN1212766.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            8301..9110
                     /locus_tag="L1U99_002239"
     CDS             8301..9110
                     /locus_tag="L1U99_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBN1212767.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(9213..9842)
                     /locus_tag="L1U99_002240"
     CDS             complement(9213..9842)
                     /locus_tag="L1U99_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HBN1212768.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            10012..11304
                     /locus_tag="L1U99_002241"
     CDS             10012..11304
                     /locus_tag="L1U99_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1212769.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(11380..12042)
                     /locus_tag="L1U99_002242"
     CDS             complement(11380..12042)
                     /locus_tag="L1U99_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBN1212770.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            12267..12551
                     /gene="groES"
                     /locus_tag="L1U99_002243"
     CDS             12267..12551
                     /gene="groES"
                     /locus_tag="L1U99_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBN1212771.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            12602..14227
                     /gene="groL"
                     /locus_tag="L1U99_002244"
     CDS             12602..14227
                     /gene="groL"
                     /locus_tag="L1U99_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBN1212772.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4914 a         2455 c         3071 g         4088 t
ORIGIN      
        1 ccattattat ctagtctagt ccattctttt tgtttgcagt atttgtgatg gctttccgta
       61 cccttagctc agttggtcag agcagacggc tcataaccgt ccggtcgtac ttctcgtaat
      121 ccaggaaggc cgtcagctcc gtccgcagta gcgtgtttac ggccagctcc agatgggagc
      181 ggaataactc gttcaaatca cctttggtgg ctagagtctg caggagttct gtaataaaat
      241 cgttcatagg gaagtcctct tttctgtgaa tgggtgtggt aactttattc tacagaaggg
      301 acttcctttt ttctatttac acaaaatatt ttatactctc aaatgtttgt atgcagttac
      361 atctgacttt attcgaatta aggaaaagat ttataaaaat aaaataaaaa aatatatatt
      421 taaattgact tattgtgaaa tcattaacta taattagttc agtttatgtt aaggagaatg
      481 atgatatgaa taagaaaatt gtagtaagtg gattaattat aggtggatta gtgttagcag
      541 ggatcgcagg gaaaaacttt gccgatgaca ttttgttatg gggtggagaa gataatattg
      601 aacaaatcaa tcataatttg gagtcattag ataaagcact agaaaataaa gagcaaaata
      661 ttagtagttt aaattcacga ttatcttcaa ataatcaaga acttgagcaa gcaaaggcta
      721 acgttgaaga atataaacaa aaagtgttga ctttggaaaa tgataaaaat caattaacta
      781 tagagaaaac aaatttagag aatcaattat caggaaaaaa tgctgaattg caaggtaaac
      841 aaaatgaaat caatgctaaa attgatgaaa taaatcaaaa aatagctgaa ataaatcaat
      901 taaacactga ttggaataat cgtttacaaa cagaacaaaa taaatttaat gatgctcaaa
      961 atactgttaa tagtttaaat caacaaatta atcaattgtc aaatgaaaaa aatactatta
     1021 aaaaccaatt gcaaagtact gaacaaaaac tagaaaaagc gcaatcagaa aacagtaatt
     1081 tgaataatta tattgaaaaa ctggaaaaag ccaaaagcga tgtagaagac acagcaaaca
     1141 gatcacaaga aatcgtgact gaacatacag gaaaatagat gcatttttta gtttaaattt
     1201 ctttaacaaa atagtatttt gttgctaaat aatttttatt tgaatattct acaatgatat
     1261 ctcccctcaa aatggagggg aagtacatac tgtgataatc tacaggttta ttgactgatt
     1321 aggatgttat taaaaaataa aatactaaaa tgcatacccg aatttcatac ccgaaaaata
     1381 aaaaatgcca ccacgtacac tcttttcgaa actacctaag tagccaagaa tgtactggtg
     1441 acgtgggttt ggcacccaat gggccgtgag gggctcgaac ccgcgacccg ctgattaaga
     1501 gtcagctgct ctaccaactg agctaacggc ccgtacaaaa agtacttaat aatagtagca
     1561 ctaagaattt taaaatgcaa gactacattt aaagaaaatc agaaaaatct ttacttcctt
     1621 ataggaaatc attcatagat tattcacatt tgctcgctat tatataagca taccaacaaa
     1681 caaagttctt gcaagagaac aaaccctaac acttttttca ttttttactc ctttcccgcc
     1741 gtctccccgg cgggtctcct gttcttaacg ataaaagaca agaaggctta gccttcttgt
     1801 tttttgtttt catggaatcc cgctaatcaa atcacctagt taaagcaact agattgaatg
     1861 tttatcataa gtctgatatc atgtttatga aatgaaaaaa ggagcggtta tgatggaaaa
     1921 aatgcgtcag caattaatgg agtgggggaa ggaactagaa acattccgtc tgcctcactg
     1981 ggaagaactc cctgacttag aactttatat ggaccaagtc agaacgttag ttgatcgtta
     2041 tctttcacct gtgatacaag gagaaaagca tccattgctt acctcttcta tggtaaacaa
     2101 ttacgttaaa ctaggtttga taccagcacc agttaaaaaa agatataaca aagaacacgt
     2161 agcattttta cttgcaatca ctacgttgaa acaagtattg actattcctg aaatcaaaga
     2221 agggatattg ttccaaggaa aaacagtagg aattcgtgaa gcctataatc tattttgcga
     2281 tgaacaagaa gcagctgtgt ggatggtcag ccaattagca caaggtaaat ctcatccgca
     2341 aaaattcgac caggcaaccc ctgtagaata tattgctgta agagcggcaa ctttatcgtt
     2401 tgcaatgaaa cttcttgcgg aaaaaacgat tgttctagaa accgaatatt taaaagagga
     2461 gaaaacaaat gaaaaacaat aaaatcgcaa ttttagtaga ttcaggtacg gatgtgccag
     2521 aagaattgat aaaaaaatac gagatgtata tgatcccatt gaaaattatt tataaagatc
     2581 aggtatatac agataaaatt gacattacct ctgaagagat ctatcaacgt ttgccagagg
     2641 aaatccctgg tacatctttg ccggatggtg agtcgatcac agaaatcttt gagcaaatca
     2701 aaaaagacgg ttatgaaaag gtacttgcgg taacaatttc cagtggattg agcgggacat
     2761 ataatgtggt tcgtttaatt gcacaacagc aagaagaatt ggaagcatat gtactagata
     2821 cgaaaaatat tggtattggt gcaggttttt ctgcgatcca agcagcaaaa tggctggaag
     2881 aaggagtaga atgggatcaa ctgatcagta atctgaatga gttagtcgaa agaacaaaag
     2941 ttttctttaa tgttgcgaca ttggaatatc ttcaaaaagg tggacggatc ggtttagttg
     3001 cttctattgt aggaaccgct ttaaagctta acccaatcat ctcatgtaat gaagaaggga
     3061 tttattacac agtaggaaaa gctaggggac gtaaaaaaag tttggataaa acggttgctt
     3121 acgtcaaaga aaaaatcggt aatgcaaagg tcttcaactt agctgttgcc catggggatg
     3181 cgaaagaaga agcaattgaa atggaagcga gacttaaaag agagttccca caagcaaacc
     3241 aaatctactt tggccagatt tctccggcat tagtagtcca cactggtccg ggattattgg
     3301 gtgtcggtgt acaagtttta gaaggataaa tcaaaaaaag gaaacactga ggtgaaaatc
     3361 agtgttttcc ttttttattg aagttagaac aaaaaataat aaagtatttt gcactttcat
     3421 tttaattttc tcttttgttt tataggcaaa gatgaaacaa aagcagaaat acggtataat
     3481 gagaaggtat gacaataata tataagaggt ggctctttat gaaaaaagtt ttagttgtcg
     3541 atgatgagaa gccgatttcg gatatcgtca aattcaattt agccaaagaa ggctatgatg
     3601 tttatactgc atatgatggg gaagaagcct tggaaaaagt tgctgaggta gaacctgatt
     3661 tgattttact tgatttgatg ctacctaaaa tggacggctt agaagttgct cgtgaggtac
     3721 gcaaaactta tgatatgccg atcattatgg taacagccaa agattctgaa attgataaag
     3781 tcctaggctt agagttaggc gccgatgatt acgtgaccaa gccattttcc aaccgagaat
     3841 tagttgcacg tgtcaaagca aatcttcgtc gcggtgccac ggctgcgaag gaaccagaag
     3901 aggcagcacc tgcggaattg acgattggtg atttgacgat ccatccagaa gcttacatgg
     3961 tgacgaaacg aggagaaaca atcgagttaa cacatcgtga attcgaacta ctcttttact
     4021 tggcgaagca ccttggacaa gtgatgacaa gagaacattt attacaaacg gtttggggtt
     4081 atgattattt tggagatgta cgaacagtgg atgtaactgt acgtcgtttg cgtgaaaaga
     4141 tcgaagataa tccaagccat ccaaattatt tagtgacacg tcgtggtgtc ggttactatt
     4201 tgcgtaaccc agaacaggag taattggatg aaaagaaaag tccgcttttt tcgatcagtc
     4261 aattttaaga tcgctattac ctttattctg attttattga tctcgatcga aattattggt
     4321 gcctacttta tacgtggttt agaacgttcc acgatcaata catttattaa agatatgaat
     4381 caaacggtgg aatcattagc aacaacaatc agcccggaat tgaatcgaaa agataatgca
     4441 gatgatgaag aggtaaatgc gaatatcaaa agatttattg aaaacagtgc gactagcgat
     4501 atcatcgaaa tacgggtcgt tgacgaaaaa gggatcatcc gaggaacaac cgatgtcaat
     4561 gaacaaagcg ctgtgggaaa gaaaaatgat tatgttgata tcaatgattt cacgactaaa
     4621 cgttatgttg ctttagataa cgacgataaa cgggtgaata tcaatgttca accgatcctg
     4681 tccccgaccg gcgatgccgt tatcggggct ctttacgtca aaagtaatat cgaacaaaaa
     4741 tattcggaaa tcaataacac agcagtcatt ttctttactg cctcactaat tgcggcattt
     4801 atttcaatga tcgtatctgt tttagttgct cgttcgatta cacagccgat cggtgaaatg
     4861 agagaacaag ccattcgaat cgctagagga gactacagtc ggaaagtcaa agtgcatgga
     4921 caagatgaac ttggacagct ggctgatacc ttcaatcagt tagctgaacg tattgaagaa
     4981 gctcaagata caatggaagc tgaacgcaat cgtttggata gcgtgctatc ccatatgaca
     5041 gacggcgtca ttgcgacaga tcgcaggggt aaagtcatta cgatcaatga tatggctgtt
     5101 tccttgctag atatcaaaaa cgaggaagca atcggacaat cgattttgac acttttagat
     5161 atcgaagaag aatatacgtt gcggaaatta ttagaagatc caaacgaaat ggtacttgac
     5221 cgttcaacca gtacattgga aagtgatcag atgatcttgc gagtagactt ttctatgatc
     5281 cgtcgcgaat caggttttat cagcggatta gtagctgtct tgcatgatgt gacagaacaa
     5341 gaaaaaacag aacgggaacg tcgtgaattc gtctctaatg tttcccatga acttcgtaca
     5401 ccgttgacaa gtatgcgtag ttatatcgaa gcattgagcg aaggtgcgtg gaaagacgag
     5461 gaagtagcac caaatttttt gaaggtaacg ctagatgaaa cagaccgaat gattcgaatg
     5521 atcaatgacc tcttaaatct atctcgcatg gatacaggta atacccagct tcaattagaa
     5581 tatgtcaatt tcaacgagtt agtgaatttt gttcttgacc ggtttgatat gatggtggga
     5641 aatcaggaaa aaaattataa gatccgtcgt gaatttacgc aaagagatct ttgggtcgaa
     5701 gtagatacag ataaaatcat ccaagtagtc gataatatca tgaataacgc gatcaagtat
     5761 tcaccagatg ggggaacgat tacttgtcgc ttattagaaa cgcataataa cgtggtttta
     5821 agtatcaccg atcaaggatt ggggattcct aaaaaagatc tgaaccgagt gttcgagcgg
     5881 ttctatcgag tagataaagc acgtgcaaga gcacaaggtg ggacaggact tggattagct
     5941 atttctagag aagtgattaa ggcgcatcga ggcgctattt gggcagagag caaggaagga
     6001 aaagggtcga ctttttatat ctcgctgcca tatgaacctt atgaggagga atggtgggaa
     6061 tgagaatctc tgaaaaagtc gttcgtatag gactcatttt gatggttgcg ttaagcatat
     6121 acttctctta tgcaatctgg ctgagcccag caggaaaaag ttcaatcaac gtagatgaga
     6181 caaacactca aatgatcgag tctcaaagca atcgaaaaac ttccgaagtc tttcttccgc
     6241 ttcatgttac atggcaccat tcgggaatga tccaagaaac caacagtgaa aatctcgtgt
     6301 accgattgca attgatcatc gataaagcaa gatttggaaa gctttctgaa gtagtttcag
     6361 gagacaaatc acagtttgaa caggtgaaaa atctgaactc tggttttgag ttggcctata
     6421 atgcgccttt tttgctaaga gaatacaagg aagcatttga tttagattta gatgtgtcga
     6481 acttggcaaa agaaagcgaa aatatgtatt ttactagaat acaattcgat caaggaaata
     6541 aaaaaatccg atttttgaat tattcgaacc atctcgtata tgaagcaaat atttcgttga
     6601 attggacaga tatcaataaa gaattaacag caaaagacac aaaatggaca gaaatgacaa
     6661 cagaaccatc gacgatcgac acgcaatatg ctacgaaaca ttcgatcaaa ctgaaaaagt
     6721 atagttatat cctgtcacag caaccctata cactttttag aaatgctttt ttccagaaac
     6781 cagatagcgt gaaaaataat gatgaaagca atgaattgat tttttacggt gggaatgaaa
     6841 caatgtctat ccattcggaa acgcaagtag ttgattttcg tggagagctg ccagagaaaa
     6901 aagaaaatgc tagtgtattt tctgaaagtt tcccctatat tagcaaatta ggcagttctt
     6961 tagggaacct cagatatttt gaccgcagtg acaatacgat cgattatcgg atattcgtgg
     7021 aaggcttccc ggtttttggg acagacagca gaggacagat tggtgtggaa gttggcggtg
     7081 aaacgaatgg ttctgtgcaa gtgaatatcc aaaccagttt gaatacgatt caagtgccga
     7141 taccttcaga cgaagaagta gaacttgcaa gtacgaatga aatcatccag cagttaaaag
     7201 ctaagggagc agatagcaac aagattggtt cagtgatcgt tggctataca tggcaaaatg
     7261 tcaaagaaac gaatcgtgtc gttgatctct tacctgaatg gtatgtgaaa tataaagata
     7321 actggtattc agctaacgac cttctggaaa aattacctgg attggaggcg aattaattgg
     7381 atttcaaaaa aatcgaatgg atatttttcg tcgctttttt agggttgaat gtgtttttat
     7441 tcagcagtta tcatgacgcg gtataccaag aaaacaatgt cattcgctct aatcagactg
     7501 aatcaatcca acaacgtctg gctagcgacg atatcactta cacggggaag atttcgtctg
     7561 agaacaagca aggctattat cttagcgcgg agcagaccaa tcttagcact tcattagcga
     7621 attatcgcaa ggctggtaaa agcggcttgc tggcaagtgg tgtgttttta gacggtgatg
     7681 ttttgacgaa atctttatcc agttcagatg ctgaaaagaa cgtgatcgat ccagataaaa
     7741 ttagtagttc cttggaagat tttttatcta acaaagacaa tattttattc ggtaatgatt
     7801 atgtgtacac gaaaaacttt tctcatttag aagaagaacc actagaaatc caagcaagcc
     7861 aagagtatga aggcatccca ttcaatgatg atacagcaaa aatcgttctt tctttagaaa
     7921 aaaacgataa tgattatagc atcacgaaat acatgcagac gcatttatct gatatcgagc
     7981 agctgcgcga aaagacggaa ctgtatacgg aagaggaagc aatcaataca ttgtacatca
     8041 ataacaaaat accaagagga tcaaaaattt tatggcgtca gctagcttat tcctgtattc
     8101 tgaaagtccg ggaaaaaaat gtgtatgttc ctgtttggca tgtagcgatc gaaacaagcg
     8161 ataaagtggt ccaaattgag agtgtcaacg ctttcagcaa tacgatcgtg acaaacaata
     8221 ctgtaccaaa agtggaagat caataaaaaa gcgagtataa tgaaaaaagt ttacaaagta
     8281 agaagggaag taggagtcaa atggctgaag aaaaaccagc ttttaaaatc agtatcctag
     8341 caagtggaag ttcgggtaat tcactttata tcgaaagtga aaaaaaacgg cttttggtcg
     8401 atgcaggact tagcggtaaa aaaatcactt ccttgatggc tcaaattgat cggacaccgg
     8461 accaattaga tggaatactt gtgacgcatg aacatcgaga tcatatacat ggcgtgggtg
     8521 tcttggctcg taagtatcat ttggatgttt ttgccaatca gcagacttgg gaagcgatgg
     8581 aaccactgat tggaaatgta ccagtggaac aaaaacatct atttgagatg gggaaagtca
     8641 gaacattcgg cgatatcgat attgagagtt tcggcgtctc ccatgacgca gcggctccgc
     8701 aattttatcg tttccataaa gaaaatcggt cattcgtcat gttgacggac accggatatt
     8761 gcagtgatta tatgcgaggt gtcattgaaa atgccgatgg ttatttgatg gaaagtaatc
     8821 atgatcttga gatgttacgc atgggacctt atccgtggaa tttaaaacag cgtattttag
     8881 gagatagagg acatctttcc aacgaagacg gtgcacttgt catgactgat gtgatcggta
     8941 atcggaccaa acgaatctat cttggccatc ttagcaagga aaacaatatg aaagaacttg
     9001 ctcatttaac aatggaaaat gttttgaaag aaaaagattt tggcgttgga catgattttg
     9061 aaatctatga tacagatcca gatgaagcaa ctgagctatt ttcgatttaa acagttcaat
     9121 caataaaaat ataaaaagca gaagataaaa tcaatcaggg ttggttttat cttctatttt
     9181 tattttttta gcatattaaa aaaataaccg tattatcgac tgactacact gatgtgctgc
     9241 ttttcatgtt tctcatccag tatctcatct actaatgcaa tcgcgtaatc tgccatgctg
     9301 atcgtactgt cgccagcagc gtttctttgt aaataatcat cacttaacaa ataagtacct
     9361 gtacgtttgc catgtggatc aaataaagaa gctggactga tataagtcca atgtagattt
     9421 ttagattgtt tcaattttaa caatccttcg tacatattga aagctgttgg atagaagggt
     9481 gcatttttag gtacttggtc aatcatacga gtcgtctttt ctgtatctaa gaataacgaa
     9541 gaggcacccc caacgacaat taagcgtgta tcggttcctt caagcatctc aatcaaatgg
     9601 gacaaagaag tttgatgcat ttcttctttt cctttgggag cgttgaaagc atcaacgaca
     9661 acatcaaaag atgcaagatc agtagttgtc aactcaaata aatccttttg tataaacgga
     9721 acatctgatg gcaatttttc tggatgacgc acgattgccg tcacgtctaa atctctggac
     9781 aatgcttcgt ctaaaataaa tgaacctgca tggccagtag ctccaatgag tgcaattttc
     9841 ataaaaaacc tcctttttta ttcctgtcca ttgtaagcag ttgctgaata ttcgtcaaag
     9901 aatccgattt ttgaaaagct cagtgcgcat tcctttcatg gttcgtgatc attgggtata
     9961 gttaaattaa gaaaactgat tgataaaaat agaagttgaa ggagataaga aatgaaagag
    10021 tggttagatc gtgccttttt accaatgata acatctgttg tgaatcttag acccttaact
    10081 gctttgcgta atggaatgac ttacacgatc ccaataatta ttgttggctc gctgtttttc
    10141 ttatttgctc attttcctgt ggattacatc gctcagtgga tagacaaaac aggattttct
    10201 atgtatttta cacaagtata ccaggctaca tttgatgtga tagccttttg gatcgttttt
    10261 gccattgcat acgcttatgc aaaagaagaa gacatcgatc gcttaccagt cggcataaca
    10321 gccttgtctg cttatctact gcttattcag ccactaaata ctcagataga tactgtctgg
    10381 acaggtgctg aagggatact aggagcagtt acaactgggc tcatcatcgg atggggctat
    10441 gcacgtttag taagacttgc gaaagggtgg aagcaaagag agaagatacc tgaaaatgtt
    10501 tggcagtctt ttacttcatt gattccaatc attgttatag tcacttttac gcttatcggt
    10561 tcagcggttt ttcaacagtt gttcagaatg actgttgttc aaggagtatg gacatatgtc
    10621 cagcttccca ttcaatcgtt catagacacg ttgtttggtg tgcttttatt aggttttttt
    10681 gttccgtttt tatggttatt tggtcttcat ggatctgcga tggtcaatgg gttggttagt
    10741 cccgtcttgc aagcgaattc attagcgaat gcagaaatct tagcctcagg acaagagttg
    10801 acggtggcaa atggcggaca tatcgttact cagcaatttc tcgatcagtt catgacggtt
    10861 acgggtgctg gattgacgtt aggggctgta ttttttatga cggtttttgc gaaatcgaag
    10921 aaatacagag aattaggaaa tcttgctctt ttaccagcct ttttcaacat caatgaatca
    10981 attatttttt ccacaccgat cgtgatgaac ccgatgatgg ctgttccttt tattttcgca
    11041 ccggtcgttt caggattgat tacctattcc gctttatatt ttggattcgt tcctttattt
    11101 acagcagtcc aagtcccttg gacaacaccg ccgatcctct cgggtttctt agtaggcgga
    11161 gtgcctgcag cgattttaca aggtatcgtg ttgtcaatta gttttttcat ttatttccca
    11221 tttttgaaaa aaatagattc tgcaaactgc aaaaaggaaa gacagacaaa aaatgatgga
    11281 gcagcagaaa agatgaacga ctaaaaaaca aaaatactcc tgtcgcttta gattgggaaa
    11341 atcaccaatc taggatgaca ggagtattta tagtcatgtt tatactagcc ctttttggac
    11401 agctaattga acaagaacaa ctaatgtgtt cattcctacg tgtgtgatca tcgatgtcca
    11461 gatccgacca gttgctttgt actctaggct gaagaagaaa cctaggaaaa agtagattag
    11521 cagatgacca tcattatgag caaacgcaaa cagcaaagag ctgatcactg ctccgaccca
    11581 aaaatttgaa tatcgactga tgatccccag tatactgcgg cggaatacga actcttccat
    11641 gatgggtcca gcaacagttg tcgccaaaat aaaagcgggt gcttccatga tcatctggat
    11701 gatattttgt gtattctcgg aaggggttgc tttgccaaac aatacagatt ctaacatgac
    11761 agcgatgctt tgcagaatca atgcgacaaa gattccaacc aatccataaa taacaatctt
    11821 tggagcagaa gcttttttta ccgctgattc gatcgctaag ggttcacgtt gcttaaaata
    11881 aaaaatagct aggacaacgg cgcctagtat atacatgact gcagttgctg tgatcaattc
    11941 agacgtagat tttacaagtc ctatcgaagc taggatcaag ggtgagataa aaattagacc
    12001 atagcaaaaa atgctgagga agctatattt ttttaaagac atgtaattcc tccttttaag
    12061 ggataacaag catgcaaggc aagcttatat cgattgattt caattatatc ataatttcaa
    12121 taagcagctg tcagaataaa atttcttttc tttgatttaa aagcttgcaa aaaagaggga
    12181 gaatgagtat tattaaaaat gtaggttagc actcgaaggt taagagtgct aacagattaa
    12241 aaaaagagtt atcggaggga tttatcgtgt taaaaccatt aggtgatcgc gtcattatcg
    12301 aagtcgcaaa agaagaagaa aaaactgtcg gaggaatcgt tttagcttct gctgctaaag
    12361 agaaacccca aactgggaca gttgttgcag tcggtgaagg ccgtttgtta gaaaacggtg
    12421 aaaaagttcc tgccgctgta aaagcaggcg accaagttat gttcgaaaaa tacgccggta
    12481 cagaagtaaa atacgaagga aaagaatatc tgatcgtcgc aggaaaagat atcatggcga
    12541 ttgttgagta aatttggaag ataaaaaaat aatcaaaaat aatcaatgag gtgaatcaat
    12601 catggcaaaa gaattgaaat ttgcagaaga cgcacgcgca gctatgttac gcggggtaga
    12661 taaattagca gatacagtga aagtaacatt aggacctaaa ggccgaaatg tcgtactaga
    12721 aaaatcttac ggctctccat tgatcacaaa tgatggtgtg acgatcgcaa aagaaatcga
    12781 attagaagat cattttgaaa acatgggtgc aaaacttgta tcagaagtag catcaaaaac
    12841 aaatgatatt gcaggagacg gtacaacgac agcaactgtt ctgacacaag caatcgttcg
    12901 cgaaggttta aaaaacgtaa ctgcaggtgc taatcctcta ggcattcgtc gcgggatcga
    12961 attggcaaca aaagcagcag tcgaagaatt gcataatatc tcaactgttg ttgattcaaa
    13021 agaagccatt gcacaagtag cagctgtttc ttcgggttct gataaagttg gacatttgat
    13081 tgctgatgca atggaaaaag ttggaaacga cggtgtcatc acaatcgaag aatcaaaagg
    13141 gatcgaaaca gaactagatg ttgtagaagg tatgcagttt gatcgtggtt acttatcaca
    13201 atatatggta acagataacg acaaaatgga agctgttcta gaaaacccat atatcttgat
    13261 cacagacaaa aaaatctcta acatccaaga tattctgcca ttgttagaac aaatcttgca
    13321 acaatcacgt ccattgttga ttattgctga cgatgtagat ggtgaagcat tgccaactct
    13381 tgtattgaac aaaatccgtg gaacattcaa cgtagtagct gtaaaagctc ctggtttcgg
    13441 cgatcgtcgt aaagcaatgc ttgaagatat cgctattttg acaggtggta cagtaattac
    13501 tgacgatcta ggtttagaat tgaaagatgt aacaatcgaa aacttaggaa atgcttctaa
    13561 agttgttgta gataaagaca atacaacgat cgtagaaggt tctggagaaa aagaagcaat
    13621 cgaagctcgt gtgcaattga tcaaaaacca aattgctgaa acaacttctg attttgaccg
    13681 cgaaaaatta caagaacgct tagctaaatt agcaggtggt gtagctgttg ttaaagttgg
    13741 tgcagctact gaaacagaat tgaaagaatt aaaattacgc attgaagatg cattgaatgc
    13801 tacacgtgcc gcagtagaag aaggaatggt ctcaggtggt ggtacagctc tagtgaacgt
    13861 tatcagcaaa gtttctgctg tagaagcaga aggagacgtg gcaacaggta tcaagatcgt
    13921 tgttcgtgct ttagaagaac caattcgtca aatcgctgaa aacgctggtt atgaaggatc
    13981 agtgattgtt gataaattga agaacgtgga actaggcact ggtttcaatg ctgctactgg
    14041 agaatgggta aacatggttg aagcaggtat cgtagaccca actaaagtaa cacgttctgc
    14101 cttgcaaaat gccgcttccg tttctgcctt gttattaacg acagaagcag tcgttgcaga
    14161 taaaccagaa ccagcagcgc cagcagctcc tgcaatggat ccatcaatga tgggcggtat
    14221 gatgtaagaa aaagcaactt gcttatctac aactgatcat tagtgaaaga cagataaaaa
    14281 gaggctggaa cagaagcgtt taactccaag aaataagaag aaattcacgg aaattgcttt
    14341 tcaaattttt gtgaatttca gcttatttcc gaaggagttg cttctgcttc cgctgtttat
    14401 acgtgtttag agcgtgagac aaaagtgttc tttacttttg tcccacgctc ttttttgtgt
    14461 gtaattataa tgaaaatagt tatttttaat agttataata ttttatctat taaaagtaaa
    14521 tatccatt
//
LOCUS       DAFLVO010000069        14476 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.069, whole genome shotgun sequence.
ACCESSION   DAFLVO010000069 DAFLVO010000000
VERSION     DAFLVO010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14476
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.069"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(227..1114)
                     /locus_tag="L1U99_002245"
     CDS             complement(227..1114)
                     /locus_tag="L1U99_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1212773.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(1111..1980)
                     /locus_tag="L1U99_002246"
     CDS             complement(1111..1980)
                     /locus_tag="L1U99_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1212774.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(2117..3403)
                     /locus_tag="L1U99_002247"
     CDS             complement(2117..3403)
                     /locus_tag="L1U99_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1212775.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            3676..4254
                     /locus_tag="L1U99_002248"
     CDS             3676..4254
                     /locus_tag="L1U99_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBN1212776.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            4254..5183
                     /locus_tag="L1U99_002249"
     CDS             4254..5183
                     /locus_tag="L1U99_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1212777.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            5180..6916
                     /locus_tag="L1U99_002250"
     CDS             5180..6916
                     /locus_tag="L1U99_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBN1212778.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(6979..7815)
                     /gene="pheA"
                     /locus_tag="L1U99_002251"
     CDS             complement(6979..7815)
                     /gene="pheA"
                     /locus_tag="L1U99_002251"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBN1212779.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(7812..8321)
                     /locus_tag="L1U99_002252"
     CDS             complement(7812..8321)
                     /locus_tag="L1U99_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBN1212780.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(8314..9609)
                     /gene="aroA"
                     /locus_tag="L1U99_002253"
     CDS             complement(8314..9609)
                     /gene="aroA"
                     /locus_tag="L1U99_002253"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBN1212781.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(9622..10713)
                     /locus_tag="L1U99_002254"
     CDS             complement(9622..10713)
                     /locus_tag="L1U99_002254"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBN1212782.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(10730..11896)
                     /gene="aroC"
                     /locus_tag="L1U99_002255"
     CDS             complement(10730..11896)
                     /gene="aroC"
                     /locus_tag="L1U99_002255"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBN1212783.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(11898..12962)
                     /gene="aroB"
                     /locus_tag="L1U99_002256"
     CDS             complement(11898..12962)
                     /gene="aroB"
                     /locus_tag="L1U99_002256"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBN1212784.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(12995..14017)
                     /gene="aroF"
                     /locus_tag="L1U99_002257"
     CDS             complement(12995..14017)
                     /gene="aroF"
                     /locus_tag="L1U99_002257"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBN1212785.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
BASE COUNT         4130 a         3149 c         2615 g         4582 t
ORIGIN      
        1 gacaatcagg acagtcatcg gcaatatagc agcaatcact tctttaaaat tttttagcat
       61 gtatcctcct cctttactct ttaagtttac cttaaaatga aagagttttc gagcacaaac
      121 ttaaaacgtt atcatttaat ttttctcaac ataaaataac acacgtccca aaagtatctt
      181 tttacttgga aaaatgactt tgaaggaacg cgcttattgt gtttttttat tttacagagc
      241 cgatcattcc ttgaacgaat tgcttttgca aaacaaaaaa tacgatggca gttggtaaag
      301 tagcgatgac taatccagcc atgatcattc catagtctgg tgtataggaa gcacccatag
      361 cagataaaac aagcggaacc gtccgtttat caggagattg caaagctact aagggccata
      421 aataattgtt ccagctactc atgaatgtga tgattgcagc cgcggcatag gtatttttag
      481 ccgtcggcat atacactcta aaaaaaatac ttagttcttt tagaccgtct aatcgagcgg
      541 cttctactag atcttttgga aaagatttaa cattttgtcg aaagaagaag atcaaaaaag
      601 cagtgctaac agatggcagg atgacaacca agaaactgtt gattcccaaa accgttccgt
      661 tcaattgtga aaacattcga tataaaggga tcatcaatgc cgcaaaagga accatcatcg
      721 atagcagtag aatattgaaa attaggtctt ttcgtttact ttgataaatc tcaaatccat
      781 atcctgccat tgacgaaatc agcaatgcaa acacagtggt caccaaagcg atcatcgctg
      841 aattccaaag ggaacgagta aaattcagct cattggaaaa caaattttga aaattgatga
      901 tcaagttact gccaatcttt atttttcccg atgtgatatc cacgggtgta ttcgtcattc
      961 ccaaaaccat ccagacaaaa gggaaaatgg aaataaatga taggatgctt aatgctgtat
     1021 actttaatac tgacccaatt gtcgaacgaa gttctaatgc ttgttttttg acgttggggc
     1081 gttcgattgt ttctttttct accatatttt tcatcgactt tctcctccta ctttcgtttg
     1141 gattatcgac aatatcacaa taaaggaaac aataacaaag gaaactgctg ccgcatatcc
     1201 aaaattaggc gtgaatttat aactcaaatt atagatgtat tgagataggg tggtcgttgc
     1261 atttgctggt cccccgccag taatattttg tacttcatca aaaagctgca atgtcccgat
     1321 cgtcgaagta atggaagtaa acaaaatgat tggttttaaa tttgggatcg tcactttgat
     1381 aaactgctgc catttagaag caccgtcaat agatgctgct tcataaatct ccgaatcaat
     1441 attttgcatg cctgaaagga aaaaaatcat attgtatcca gtccaacgcc aagtgatcga
     1501 aagaatgatc agaactctcg cccaaattgg atgagtcaac cagccaatcg gtgtgtcaat
     1561 cataccaatg cccaacaaca agttgtttac aaggccagat tgagaaaata gacttttcat
     1621 gatcagagaa taactgacca tcgaagtgat acatggaaga aagatagcgg ttcgaaacaa
     1681 ccctttatat ttcaactttt tatcatttaa aaggttggaa ataaaaagtg ctagaaacaa
     1741 catgatcggt acttgtacaa gtaaatacag gaatgtatta aaaaaagctt ttttaaaagt
     1801 tgcatctgtc aacatccgct gataattacc taacccgtta aatgtcatat tgacaggggg
     1861 accactttga aaagacgtga tcaaagccaa aaccatcgga ataaaaacca tgattgatat
     1921 caaaatgact ggcaagatta aaaaagcatg cccgtttttg aataaatctt tctgcttcat
     1981 tcttttccct ccaattctat cattgattat ctacatgaaa agacaagaaa gacaatatct
     2041 gtaaggcaga cgtgatcttt tttgtctttt cgtttgtctg atgaaaaagc gaagaaattc
     2101 acttttttac caccgatcaa ttagccaatt gtgcttctac ttgtttttgt gtatctgcta
     2161 gtaccttgtc tgtctcttct ccattgatga ttcgatgaag agcttcagct acgactgctt
     2221 caattgcata ggtctcatgt ccgtaattca cttctggtat ttcagatgtc catgttgaaa
     2281 aatcgtcaaa gatcttttga ccactgtaaa attcagaagc ttcttgataa gcttcttgtt
     2341 cattcgcgct aagcatcgta gatactagtc cgatttcttt cgcaagagtg cccatcagtt
     2401 cttcattcga agcaaacgtt gcttctagga aatctttcgc tgaatcttct ccagctactc
     2461 ctttgatcac ataccagcca gcgccgccaa ggttagaagc ttgcgctttt tgcagatttt
     2521 ctggaagtgc aggtattggt gcaatcttcc attttccaga ttggttttct gctccttgga
     2581 tcgttgaaga ataccaagcg ccagttgggc tagaagctac tgctcctgat tgtatcgcag
     2641 ttactccagc attccagtca gaggtttgtt cgactagatc ttctttcaaa agagtggcaa
     2701 acaattcaag accatacttt aaagatgcat tgtcttggat cgtgactgtc tccccatctt
     2761 cagatgtata ccattctcct gcctgttgca taatcatcct tactcgacca aggtcagaag
     2821 gattgacttc agcgattttc tttcccgtct tttctttgac atctcgcgct acttgaatat
     2881 actcgtccca cttcagattc tccatatcct cttctgtata acctgcttct gccatcagat
     2941 ccgtacgata gaagtttgct gttacgcccg aatcgaaagg aacaccgtat attttatctc
     3001 ctactttgtt taccgcaaat ttatacggtg caaaatgatc ttcctttaca atagcagaca
     3061 aattagcgaa tgcatctgga taagaagtca aatagccttg tatcctataa tcttcaatca
     3121 agacgatatt gggcaatcct tctgtattcc cgctcgctaa agcggtgttc agtttctgaa
     3181 cgatatcatc ctgagacatc gtaacaactt ctatctctgt ttcttcgttc tcataaactt
     3241 tttttgcttc attcactgct ttgatattga atgtctcatc ccacgcccag acagtgactt
     3301 tttcttcttt gtctgctgta ctactagcac ttccgcatcc tgttaagaaa cctgatgctg
     3361 ccgctaaaca aacgactcca gcaattaact ttctgatgtt catttttatc cgctcctttt
     3421 ccatccatta gttgtttacg tttgctacat tcatcatacc aaaatttgaa aacggtttct
     3481 ttattattca gatacttcaa aaatttctcc taaaataata aaaaaataca aatcaactat
     3541 gacaaaagga ataatcttag catctagacc aaagatcgaa atggtgaggt ttctttaaaa
     3601 taaaaatatc cttgcatttt ctcctagaaa taagtatttt taaattacaa gactattctt
     3661 aaggcgggta aaaaaatgcc aatacgcgta attcttatcg atgatgaaca gacgatttta
     3721 gatggaatga aacagttgat caattggtct gagcacgggt ttcaattaat agggactttt
     3781 tccagtccgc tgaaagcgct tgatttttct ttggtacatg caatcgatat cgtggtcaca
     3841 gatgtaatga tgcctgaatt aaatggaatc gaattatcgc ggctattaaa acagcaacaa
     3901 cctgaaacac agatccttat cctctctagc tatgatgaat ttgatatggt taaagattct
     3961 tttaaagaag gcgtcgctga ttatctttta aagcctcgat tgagtcctga tttttttcta
     4021 aattccttaa ctgccgtttc acaaaaaatc aaaaaaaagc ccaacaaaag cccaatcacc
     4081 aatcgttatg agcagatctg cgagaatctt tcacagcaga ttgctggaca aactcgtcca
     4141 ttgcttgacc ctcttctttt tgaacacacc ttgtttttct gttatatacc gaaaaacggc
     4201 cattcagttc aaaacaaggc tctaaacaaa aacagtcgat cacccattca ttgatggata
     4261 gcgacgattc gtttactatt tatcctgttt ctaccttttc ggaagaatcc ggctatgtaa
     4321 tcaatactga ttccaaagat acacttagga agtttgttca aaagtttcgt caagaagttt
     4381 ttccaggtga tttttttgtt gtttctgatt cttttgcaat ccaagatatc aatgaaatat
     4441 tccaagagat cagaaattgc accaaaggac aacgtttcta tcataaggga aagaaccttg
     4501 cttatcagca tgaacttctt ccgttattaa ccaaccacga gcagcaagca agtagttatt
     4561 taacaaaaat cgttcataaa gactacgctt tagctgtcaa agaacttgag aatttcttca
     4621 cgacgatatt ggaacagcct attgatccag cttatttgaa acatgaggca atcaatcgtt
     4681 tctatgcatt actcaacgct ttggctgacg agcatgttgg gaatgaagaa ctttctttgc
     4741 tcaagatcgc ccttccttct ttattagccg atgctgagta tttcgaagat ttttctattc
     4801 ttgtcaaaga aacacttgag aaactcaccc acttttctgc aaatgcaaaa aaagacaatt
     4861 tcgatatctt gactttgatc tacgagttcg tccaggaaaa ttatgagaaa gaaatcaatt
     4921 tacaactttt atccgaaaaa tatcattttt catatagcta tctctcagcc atctttactg
     4981 aaaaatttgg tatcaacttt tcaaaatatc taaaaaaagt ccgtatcagt aaagccaagc
     5041 tctttttgac ggaaacacgg cttactttga cggaaatctg tgagaaagtc ggctataccg
     5101 aactgggtta tttctccaga gtttttaaag aagagacagg aatgacacct tctcaatacc
     5161 gtaaaggaac ttttgtaaaa tgagaaaaaa aatcaaagag catgaactct ttgccaaact
     5221 tctgttcatt ttgttcatcg gtctttttct gcaagccatc gtcatttctt tgtttattta
     5281 tcatcgatca agggatgcct atatccagct gttcaatcaa tcgaatgatg tggtactaaa
     5341 aaagattcaa tctgaatttg aaagtttgaa tgatacaatc gagaatacat tagccgcttt
     5401 tgattctaat ccagctgtca aaagctattt ttccaatgat ccagcccaac atatggaaca
     5461 gcttcagcaa ctaagaacaa tccaaaaaat gaatgactct ctttcaaaaa tccatccaat
     5521 gatcgattac gatgtattga tctttggaga aaatggaaga acttttgtcg gaaacgacat
     5581 gctcactgcc gtatctgccg attctttttt tcaatctgcg attgctcaga gagtgaatga
     5641 acgtgctgct gatacacaaa tgctttttgc acaccacgga ttgactcttc gcgataagaa
     5701 agcacccagc gtcttctttg tcaaaaaact gaaaaataca ttgaatcacg tttacggata
     5761 tgctgtttta tcgatctcat ccaagcaact agcgaatctt tttcaatctg tagtaaatcc
     5821 tgagatatcg aagatctcct tcatgaacga agaacagacg atcatcgcat caaatgaaga
     5881 aaatacaatt gggagccgat caatgatttt caaaaaacta acagtaggtg aaacaacgat
     5941 ttcaaatgga cagcagttga cccgtcttcc tctgtaccgc caggattgta cattactcag
     6001 tcaagtcgat cttcattctt tatctaacca aatgggcgtg atttttccga ttattttgta
     6061 taatatcgtg acacttgctt ttgctggctc attggtattt atgtatttgg atcgacacac
     6121 aaaatcgatc taccgcttga ttgattcgct aaaacggcta gaggaagatg gcttaaaagc
     6181 tactgttcct gtacaaggaa gccatgaagt ccaattgcta gggaatacga tcaatcaatt
     6241 gctaagtaat gctcagcatc attatgaaca gacgatccaa gacgaaaaga agaaacgttc
     6301 gcttgaaatc caaactatgc aagcacagat acagccccat tttatttata atacgctgac
     6361 tagcttgaaa tttttgattt ggcagaaaaa aacagatgaa gcagttcaag gaatcgacag
     6421 tttcattact ttactaagaa gtacgattgg gaaaaaagaa gaagtgattc cagtcaagga
     6481 agaaatcaaa agcgtacaaa gttacatcga tcttttgagt atgcgatatg gcgaaagaat
     6541 ctcggctaaa ataatgattc ctgatgaact gcagtcatta tctatgccga atatgatcct
     6601 tcaaccaatt atcgaaaacg cctatcttca tgcttttcac aataaaacgc aaggattcat
     6661 cacggtgtac ggcaaaacaa aaaatcagct tcttttattc gaagtgattg ataacggcga
     6721 tggcttcgat actgaaaata ccaaacaaaa aaatgatcat ttttcaggaa tcggcatcag
     6781 ccatgtagat gagcggatac gcctaatgta tggcgatgca tatggcttaa cgatccaatc
     6841 agtgattggg acaggaacga ctgtaacgat ttgtctaccg cttcttccta aaaatcaatc
     6901 agaatatcaa aaataaagaa tagccaagcg ctgatttttt tattttaagt taaataaatc
     6961 aatcagtatt cttgactttc atctacgcgt ctcttctact gtcagcactg gataacagcc
     7021 caatatttga ctttctcctc cgagcatctt gatttcttgg agcgcattct ctactaatgt
     7081 cattggacgg tccaacaaca aatcgatcac gaaaaaatat tctcccaagc tagttttcaa
     7141 tggtcgggat tcaatcttac ttaagttgat ttcccgccag ccaaaagctg ccagcatttt
     7201 atgaagcatc cctggccgat tagcaggtag tgtcaagatg acactcattt ttactggagc
     7261 tgactgctgg ctggtcatct ttcggtcacc gacgatccaa aaacgtgtct ggttcaactc
     7321 attatcttgg atattctcag ctaagatctc caatccaaca tgctgtgctg tttctaatga
     7381 agcaatcgct gctgcgtctt ctttcggatg ttctgctaca tacattgctg cagcagttgt
     7441 tgattctgtt gctactaaag gaacattagg ataatgcgtt tctaaaaact gttgtgattg
     7501 tgctagtgct tgtggatgtg aaaggatttt tgtaatcttt gttgctggat tgcctaaaag
     7561 ctgctgcttg ataggaagaa cgatttcact tttaacttcg acttctggat gtttggaaag
     7621 aagatcgatt gtgtgatgaa cagctccttc caatgaattc tctacaggaa cgacagccag
     7681 atcgacttgt ttgcgaaaca aagcgcgcaa acaaacaggg atggaagcat acgcagtcaa
     7741 ttgttctgta ggaaatagct gacaagccgc ctgataagtg aatgaacttt ctggccctag
     7801 atagctgacg ttcatatgct tttgatcctt tctataatgg tatcgatgat cttttctggt
     7861 gtttgattgg tcgtgttgat tcgatgtgtc gcactttctt cataccaaga aagtcgttgt
     7921 gccaataatg cttttatttc ttctcttgtt tttccaagag ctaaaggtcg aatagacgtt
     7981 tcatcttgtt ggatacgatc aactagacag tccgcttctg cctctaagta aagaacaatc
     8041 ggctgtgttt ttaaaaaacg ccgattttct gcactttgga caatccctcc accagtcgcg
     8101 ataattttgt cttcatttga cagctttctt aaaatatctg actccacttt tcgaaagctt
     8161 ttttcaccgt aatagtgaaa atattcggca atcgacaatt ggatatgttc ctcaatcttt
     8221 gtatctaaat ctacatactc tttttgtaaa cattgagcta accctttacc gattgttgtt
     8281 tttccagcgc ccatgaaacc aatcagcaaa atgctagcca tgagcttctc ctcctgacac
     8341 aagttctgct aaatcgtcaa aaaatgccgg ataagagatt gaaacagctt cagctccttc
     8401 tagttcgcaa ggtccatcag ctatcaaagc agctacttgc agcatcatac cgattcgatg
     8461 atcgcctctg ctggacactt ttgcgccatg cagaggtgtc ggcccatgga tgatcagacc
     8521 gtctgctgtc gcttttatct ttgctcccat tttctgtaat tcttctgcca ccgcatcaat
     8581 tctgttggtt tcttttactt ttaattcttc tgcgtctttg atgatcgtga ttccttctgc
     8641 ttgagtagcc actaaagcta gaatgggcaa ttcatcaatc agacgcggaa tgatttctcc
     8701 accaatcgtt gctttcttca aatgactcgt cttgacactt aaatcagccg attggttctg
     8761 ttcattgtga ttcgtctggg taatcgctgc gcccatctcc tccaacacat ctaagatacc
     8821 agttcttgtt ggattgaccc cgacattttt taacaacagt tggctttccg gaacaagaag
     8881 tcctgctgct agaaagaaag cagctgatga aatatcacct ggaacagtta tctgttgacc
     8941 agttaatttt tgcggtccgg tcactatgat cgttttatct tccactgtga tccttccgcc
     9001 aaattgacga atcatttctt ccgtatggtt acgggaacgt tctttttcaa cgattacgga
     9061 tgtgccttct gcttgtaatg ccgcaaacag caaagcagat ttgacttgcg cactggctac
     9121 aggcatattg tatcggatag gtgataaaga gcgggttcct gtcacagtga ttggtagata
     9181 ctggtcattt tcttctcctt gcaagtcagc gcccatctcg cgtaaaggtt ccatcactcg
     9241 ccccattgga cgtttagaca acgaagcatc cccgaacaga gtagtcgtaa aaggctgtcc
     9301 agccaaaata cccatcaata aacgtatggt cgtaccggag tttcccatgt caattgattc
     9361 ggttggttgg acaaatgagt ggctaccgcg accatgaatc ttgatcacct cttcctcttc
     9421 ttcgatctcg acacctaatt gttggaaggc atgtaaagta ctcagacaat cttctgcgcg
     9481 caaaaaattt tgtatagtcg tcgttccttc agcaattgct ccaaacatga tgctgcgatg
     9541 ggaaattgat ttatctgctg gtatcctaac agtccctctt aatccatgta tttgttgtaa
     9601 taattgcatt tatccagcct cctatttgat ccagcaatga taactggtat tagacataat
     9661 gattcttttt gcttgtaaca aatcctgttg gtttttaaaa ctgatttgca gtattcctaa
     9721 aatatcttcc ctggtctctt ggatcttcaa attaatcaaa gaaactcccg cttttccgat
     9781 cagtccagtt acttctgcaa taacgccagg ttcatctggc acatcgataa ataaatcaaa
     9841 aaaggcagga atcgcgcctt gcttatggac aggcaactgg tctcgacttt cttttgcccg
     9901 attgaaaaaa gaaaagattt ccgattggtt ctcagtcatg atccattctg ctatttgtgt
     9961 catttcttgt tgccaatctg ccaatcgttc caataatatc tgcttattgc tcaacaaaat
    10021 atctgtccac atgacaggat ctgaggaagc gatcctagtg atatctcgaa agcctcctgc
    10081 tgccagttgt ttggctcgcg gatactcttg attgaattgt tctgcctgat tgactaagcc
    10141 agctgccaga atatgtggaa aatgacttag cattcctgtt atacggtcat gttctcttgc
    10201 tgtaagagtt acatattttg ctttggttcc gcaaaatagt tcttgcagtt tttcaacatc
    10261 ttttttcgtc ttttccaaag gtgtaaagat gtaataggca ttttcaaata gtttagcatc
    10321 tgctgcctgt atacctgatt tatgagaacc agccattgga tgtccaccga caaaccgaag
    10381 atttttctgc tcagcggatg tcacgacttg ctgcttcgta ctgctgacat ccgtaatgat
    10441 gacgtgatca gacaagttga ttctttcaag gacatcaaga taagctaagg ttgtacggac
    10501 gggaacggct aataagataa cgtctgcttg ttctgcacct gtttcaaaat cacttgcaac
    10561 gtaatcaacg atctgctgtt ctactgcttg ctcacgggtt tttgactgac tatcccaacc
    10621 aactactatc agttctggat tggtctgacg aatacaaagt gccatagaag caccaatcag
    10681 tccaagcccc acgataaaaa catgttgtgc catcttattt gccccctttt tagtaatgtt
    10741 tcaagtagtc acggtactcc ttcactgcag ctttcaactc aacaagcgaa tcacttggga
    10801 attttgacaa tagctctgtc gctaccacag tggctacaac attttccgca acgacgctag
    10861 ctgcaggaac tgctgtacta tccgaacgtt ctacacttgc tttgtaaggt tcttttgtat
    10921 cgatatcaac actttgaagt ggcttgtaca atgtaggaat gggtttcatg accccgcgaa
    10981 tgacaagtgg ttcgccattg gtcattccgc cttcgaagcc gcctagatta ttggtacgtc
    11041 ggaaatagcc tctttcttct tcccatagga tctcatccat cacttctgag cctggtaatg
    11101 aaccagaagt gaatccgacc ccaaattcta cgcctttaaa ggcattgata ctaaccacag
    11161 cttgtgcgat tttggcatct agcttcgtgt cccattgtac gtagcttcct aatccagctg
    11221 gaacgcctcc aacgagcact tctacaattc ctccgatcgt atctccattt ttctttgtct
    11281 gatcgatcaa atcttttatt ctttgctcaa ctgctggatc aacaactcgt acttctgacg
    11341 cttcagaaat ttctttgatt tcttgaatcg agatatttcc aggtatttct gcttggattc
    11401 caccaagaca aatcacgtgt cctgctacga tgatgtcaag ttcttccaga attttcttgg
    11461 caattgcgcc gattgctaca cgcatggtcg tctctcttgc agaggaccgt tcaagcacat
    11521 tccgaagatc tcgatgatgg tatttcatac cgcctaccaa atccgcgtgt cctggacgcg
    11581 gacgtgcaac tcgccgcagt gattggtctt tttcaggcac ttctgctaca gacatgacag
    11641 ttgtccaatt tttccaatct ttattttcta ccactaaagt gacaggtgaa ccaattgttt
    11701 tgccgtgacg gatgccagac gtgatccgaa cacgatcttt ttcgatcttc atccttcctc
    11761 ctctgccgta accagcttgt ctgcgagcga gttcgtgatt gatttcttct tctgacagag
    11821 gtaatcctgc tggtagtcct tcaataatgg ctgttaattc tggtccatgg gattctcccg
    11881 cagtcatata acgcatctta cagtcctcct aagtaatctt tgaatgtctc tgtgggaaca
    11941 ggaacgattt ttgcttgccc aatcttttct agcaagatga tattcaattg gcttcctctt
    12001 gctttcttat catgggttat cgcgtggaat aattcatctg gatgacttag atcgtacgta
    12061 atcggcagat ggaatttttg aagtatcctt tctaaagcag ctgtcgatcc agttggagac
    12121 aagccgattt tttctgcatg agaagtgatg gctaccattc caatagctac tccttctcca
    12181 tgactgacta ccccatatcc tgctgtattt tcaattgcat ggccaattgt atgaccaaaa
    12241 tttaaaataa gtcgatttcc ttggtcaaag acatcttctt ccactacttt tcgtttgatt
    12301 tccaacgtag cagtaatgat tggaacagca tgttccagaa gatctttttc gtctttcagc
    12361 tcgttcagct gtttccaaag cgttgcatct gctatagctg ctgatttgat gatttcagcg
    12421 attccttctc gtaaacgacg taccggcaaa gtttttagaa cctcaggatc aatcaataca
    12481 ccagctggct ggctaaatgt tccgacaagg tttttcgctt tgtttgtatt gactgctgtc
    12541 ttcccgccaa tactagaatc tacttgtgca agtagcgtag tcggaatttg aacgaaatgg
    12601 atcccacgca tgaacgtcga ggccacgaat gctgctagat cacccaccat tcctccacca
    12661 agtgcaagta tcccatcgct gcgggtaaaa tcattatctg ctaaaaaatc gtataactca
    12721 gctgcttgtt ctaaagattt actggtctca cccgccggta cgattgaaag gactggttca
    12781 aaattagctt gtctcaattg gaacatgatt ttttctgcat atagtggagc aacgtttgta
    12841 tcagtgatca cagctacttt ttgaggtctc caaatcgttt gaagccatga tccagcctgt
    12901 tctagtgcgc ctttttcaat atgaatatcg tatttttggt tatcaacatg tacagtaagc
    12961 attcgtttca cttctttctt ttaaaaagct ggaattaatc gagtgtctga atcttttcca
    13021 ttgcttcttt catgatcgca acttctttca tcatgcgtga gtaagtcttt tcattcaacg
    13081 attggggacc gtctgaccaa gcatttgcag gatcaggatg gatctctacg atcatgccat
    13141 ctgctccgct tgccacaccc gcacgagcca ttggtggtac aagttcccaa attcctgtac
    13201 catgacttgg atcaacaatc acagggaaat gagttaattt tttcatcaat gggacagcac
    13261 ttaaatcaaa cgtattacgt gtcgctgttt cgtaagtccg aatcccacgt tcgataaaaa
    13321 tgacaggaga tttgtcttcg actgcaatgt attctgcagc attaagccat tcattgatcg
    13381 taccggaaat tccacgtttc aatccaacag gtttacctgt tttaccgaca gcagatagca
    13441 gtttaaaatt ttgcatatta cgtgcgccaa tctgtaggat atcgctgtac tcagccacca
    13501 tatcgatatg cccttcatcc atcacttcag taatcacttt cattccaaat tcatcagccg
    13561 cttgacggat gtatttcaat ccttcttctt ctaaaccttg gaaagcatat ggagaagtac
    13621 gtggtttgaa ggcaccacct cgcagaattt ttgcgccccc ggctttggcc attcgcgcac
    13681 attctctgat ttggtctaat ccttcgatag aacaaggacc agccatcgtc acgaaactgc
    13741 cgtcaccaat ttttactccg tctacatcca cgactgtatt gccaggatgg aattctcgag
    13801 aagtcaattt gtatgtgttt aaaatacgca cagcattttc tactccttca tagcgtgtaa
    13861 atgctccttc ttgtaaactt cgcgtatcac cttttagtcc aatcactact cgttctgttc
    13921 cttgatcgat tgagactttg aatccttctt tttcgatatg atcgacgact ttttttattt
    13981 gttcttccgt tgcttctttt ttcataatta ctatcattgt ttttcccgct ttcttttgtt
    14041 tacttatcta tcttggctga ttttctctac tttttcaagg tggttttaca ttaattccta
    14101 ctaaatgacc gtgtcctgtt gttctcattt tcgctccttc tttcctactt atgacccaga
    14161 taatcaacaa aaaaagatgt ccctgtagga aattgcctct acagtgaaca tcttcaacga
    14221 gccttaaaaa gcgctgcaaa aatataaaat agccactata gatgaatttc tctacgtggc
    14281 tgtaagtcgt gtttaaaaat ctttagccat catagataca aacctggttt gtttgtaccc
    14341 acgaagtcat gaatacaaac ctatctaaaa tagctaaagt aatacgtatt cagttttgta
    14401 agttttctag atttcataaa aaatcgctcc aaactgatgt aagaattgta cctagtatag
    14461 acataaaaaa atcgac
//
LOCUS       DAFLVO010000070        14280 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.070, whole genome shotgun sequence.
ACCESSION   DAFLVO010000070 DAFLVO010000000
VERSION     DAFLVO010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14280
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.070"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(41..3715)
                     /gene="rpoC"
                     /locus_tag="L1U99_002258"
     CDS             complement(41..3715)
                     /gene="rpoC"
                     /locus_tag="L1U99_002258"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBN1212786.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(3773..7390)
                     /gene="rpoB"
                     /locus_tag="L1U99_002259"
     CDS             complement(3773..7390)
                     /gene="rpoB"
                     /locus_tag="L1U99_002259"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBN1212787.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            8118..9086
                     /locus_tag="L1U99_002260"
     CDS             8118..9086
                     /locus_tag="L1U99_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1212788.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            9104..10009
                     /locus_tag="L1U99_002261"
     CDS             9104..10009
                     /locus_tag="L1U99_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1212789.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            10006..10812
                     /locus_tag="L1U99_002262"
     CDS             10006..10812
                     /locus_tag="L1U99_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1212790.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            10948..11937
                     /locus_tag="L1U99_002263"
     CDS             10948..11937
                     /locus_tag="L1U99_002263"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBN1212791.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDVK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(12254..12778)
                     /locus_tag="L1U99_002264"
     CDS             complement(12254..12778)
                     /locus_tag="L1U99_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HBN1212792.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            13065..>14280
                     /gene="scm"
                     /locus_tag="L1U99_002265"
     CDS             13065..>14280
                     /gene="scm"
                     /locus_tag="L1U99_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBN1212793.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDT
                     SASSDSTDTTSTT"
BASE COUNT         4050 a         3090 c         2815 g         4325 t
ORIGIN      
        1 gttgtgacaa taatttgtca caacctcttt tttaaaatat ctattttgtt tgattgttca
       61 ttgcgtcttc tgcagccatt tgcgcttcaa tatctgaaat actgtagaca ttttcgcttg
      121 ctacaccgac ttcttttggt tccatgtcac gataacgttg cataccagta ccagctggga
      181 tgatcttacc tataataaca ttttctttca aaccaagaag aggatctttc ttaccgcgga
      241 tcgcagcatc cgtcaagaca cgagttgttt cttggaatga tgcagcagat aagaaactat
      301 ttgtttctaa tgatgctttt gtgataccta gtaagacagg tcgagaagtt gcaggaacgc
      361 ctcctgagac tagcgtattg tagttttgat ctttaaagtc tgcgatgtct aataatgtac
      421 ctggtaagat atctgtatca cctggatcca ttacacgaac tttacgcagc atttgacgaa
      481 ccattacttc gatatgcttg tcgccgattt ctaccccttg catacggtaa acacgttgta
      541 cttcacgaag caagtagttt tcaacagata atacatcgcg aacttgcaac aattgttttg
      601 gatcgattga tccttctgtc aatggtgcac cacggtggat catatcgcct tctgctactt
      661 tcatacgtgc tgtataagga acagtatacg tacgtgtatc tgtttttcct ttgattgtta
      721 cttctttggt acgtgttgca ggatcttctg agatatcgat gacatcccct gttacttctg
      781 tgatcactgc ttgccctttc ggattacgtg cttcaaagat ttcttggaca cgaggaagac
      841 cttgagtgat atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc gtcaactgag
      901 taccaggttc accgattgat tgagcggcga tcgtaccaac tgcttctccg acttcaacgt
      961 cagagccagt tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt tttgtattac
     1021 atgtgaagac agaacggatt gtcactgttt cgacacctgc atcaacgatt tgttttgcga
     1081 tgtcttcgga aatcaattgg tttcctgcaa tgatcaattc atttgtttca ggatgacgta
     1141 cttctttacg ggtgtaacgt cccactaaac gatcttctaa tgattcgatg atttcatttc
     1201 cctcgcggat ggcttggatt tcaagacctc ggtcagtacc gcaatcttct tcacggatga
     1261 ttacatcttg ggccacgtca accagacgac gagtcaagta acctgaatcg gcagtcttca
     1321 aggctgtatc ggtcatccct ttacgagccc cgtgagttga gataaacatt tccaagacgg
     1381 atagtccttc acggaagttc gaaatgattg gcaattccat gattcgacca ttaggagcgg
     1441 ccatcaaacc acgcattccg gcaagctgtg taaagttgga aatgttacca cgagctccag
     1501 aatcagacat catgaagatt ggatttttcg cttccaaacc ttccatcagt ttttgttgga
     1561 tgctgtcttt tgcagcattc caaacagcaa tgacacgttc ataacgttcg tcatctgtga
     1621 tcagaccacg acggaattgt tttgtaatag tttcaacttg tttatgggca ttttcaatga
     1681 tttcttgttt ttcattcagt acactgatgt cagcgatccc tactgtgata ccggcatgtg
     1741 tcgaatgttt gtaccctaag tctttcatac ggtcaagcat cttagaagtt tctgttactt
     1801 tgaatcgttt gaagacttct gcgatgatgt ttcctaagtt tttcttcttg aacggtaata
     1861 ctaattcttg ctctttgata tgtgcaggaa tatcagtacc agcttcaaca aagtatttgt
     1921 ccggtgtttg gacggtcaag ttgaagtctg ttggttcatt cagataaggg aattcaggag
     1981 gcatgatctc gttgaagatg atcttaccaa ctgttgtgat catcgtacgt tctttttgcc
     2041 attcagtaaa tggtttttca cctaatgagt tagggttcac accgatacgt gaatgtaaat
     2101 gaacatatcc gttgcgccat gcgataacgg cttcgttttg atctctgaag accattcctt
     2161 cgccttcgcg tccttcttct tccattgtca agtagtagtt acctagaacc atatcttggg
     2221 aaggagtaac aactggttta ccatctttag ggttcaagat gttttgagca gctaacatca
     2281 acatacgtgc ttctgcttgt gcttcttcat tcaatggaac gtggacagcc atttggtctc
     2341 catcgaaatc ggcattataa gcttcacata caagtggatg caaacggatt gcgcgtcctt
     2401 gtactaaaac tggttcgaat gcttggatac caagtcggtg aagcgtaggt gcccggttca
     2461 gcaatactgg gtgttccttg attacgtctt ctaaaacatc ccatacttcg tcttcttgac
     2521 gttcgatttt acgtttcgca tttttgatgt ttgaagctag ttcgcgttga acaagctcac
     2581 gcatcacgaa tggtttgaat aattcaatgg ccatttcttt tggaagtcca cattggtaca
     2641 tcttcaagaa aggtccaaca acgataacgg aacgacctga gtagtcgaca cgtttaccta
     2701 gcaagttttg acggaaacga ccttgtttcc ctttcaacat atgagaaaga gatttcaatg
     2761 ggcggttacc tggtccagta actggacgtc cgcgacgacc gttatcgatc aatgcatcta
     2821 ctgcttcttg cagcatacgt ttttcatttt gaacgatgat tccaggtgca ttcaagtcta
     2881 acaaacgttt caaacggtta ttacggttga ttacacgacg gtaaagatca ttcaagtcac
     2941 ttgttgcaaa acgtccacct tctaattgaa ccattgggcg taaatctggt ggaataacag
     3001 ggataacgtc cataaccatc cagcttggtt gatttcctga agcgcggaat gcttctaaaa
     3061 tatccaaacg gcggattgca cgtgtacgtt tttgtccttg tgcagatttc aattcttctt
     3121 tcaattcggc tgcttctgca tctagatcaa cattatcaag taattgttta atcgcttctg
     3181 cacccatagc agcttggaat tcttgtccat attgttcacg tttttcgcga tattcgcgtt
     3241 ctgtcaacaa ttgttttttc tctaaattcg tatttcctgg ttcgatgact acatatgaag
     3301 caaaataaat gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga cccatacgtg
     3361 aaggaatccc tttaaagtac cagatatgtg aaacaggagc tgctaattca atatgtccca
     3421 tgcgttcacg gcgaactttc gaacgagtaa cttccactcc gcatcgatca caaacgattc
     3481 ctttataacg gatacgtttg tattttccgc aggcacattc ccagtctttt gtaggaccaa
     3541 aaatccgctc acagaacaac ccttcgcgtt caggttttaa ggtacgatag ttaatcgtct
     3601 caggtttttt tacttcaccg taagaccagc ttctgatttt ttcgggagaa gccaaaccta
     3661 tttgcatact ttcgaattta tttacatcga tcaaaagggg ttccctccat ttcatttaat
     3721 ggcaaaccgc aagacggctg atcttcgacc gccttgcagc tcatagaccg gattagtcta
     3781 aattatcttc tgcggtttca aagttttgga tgacatcgtc tttttcatct tccacttgtt
     3841 cagcagcttt cttttctaat tctttggcag tttgctgttc ggcaaatttt gtcaaagcat
     3901 caacagtgat caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc tctgtttctt
     3961 cgatatccaa gacacgcatg tccagaccta gtgattgcaa ttctttcacc aatacgcgga
     4021 atgattccgg tacacctggt tttggaattg gttcaccctt gacgattgct tcgtatgttt
     4081 tcacacgtcc gactacgtca tctgatttgt atgtcaagat ttcttgtaaa gtataagccg
     4141 caccgtaagc ttccagtgcc catacttcca tttcaccaaa acgttgtcca ccaaattgag
     4201 ctttacctcc caatggttgt tgtgtaacca atgagtaagg tccgattgaa cgtgcatgca
     4261 atttgtcatc gaccatgtga gcaagtttga tcatgtacat cacaccgaca gacacacgtc
     4321 catcaaatgg ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg ctggccatac
     4381 cggcttcacg aactgtttcc catacgtctt catcacttgc accatcaaat actggcgttg
     4441 ctacgtggat acctaactga cgtgcagcca tacccaagtg taattccaat acttgcccga
     4501 tgttcatacg tgaaggcacc cctaaaggat tcagcatgat atcgattggt gttccatcag
     4561 gtaggaatgg catatcttct tccggcataa tacgggatac aaccccttta tttccgtgac
     4621 gaccggccat tttatcccct tcatggattt tacgtttttg aacgatataa acacgaacta
     4681 acatgtttac gcctggtgac aattcatctc cagcttcacg agtaaagatt ttcacatcgt
     4741 gaacgatacc gccgccgcca tgtggtacac gtaatgatgt atcgcggact tcacgagctt
     4801 tttcgccaaa gatcgcatgc aatagacgtt cttctgcaga taattctgtt accccttttg
     4861 gcgtgacttt ccctacaagc aaatcgccat cttggacttc tgcaccaata cggatgatac
     4921 ccatttcgtc taaatctttt aatgcgtctt ccccgacatt agggatttcg cgtgtgattt
     4981 cttcaggtcc taattttgta tcgcgggctt ctgattcata ttcttcaata tggatagaag
     5041 tgtatacgtc atcttttacc aaacgacggc tcatgatgat cgcatcttca tagttgtacc
     5101 cttcccaagt catgaaacca actaaaacgt tttggcctag agccatttcg ccttgttcca
     5161 tagatggtcc gtctgccaga gtatcccctt tttcgacttt ctcacccaaa tgaacgattg
     5221 gacgttggtt gtagcttgtt ccggagtttg aacgacggaa ttttgttaca tcgtatttat
     5281 ctaatgcacc gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat tcaacgacac
     5341 cgtcatgttt acataacaaa gcagctcctg agtcatgcgc tgatttgtat tccataccag
     5401 taccaaccca tggtgcttga ggattgatca acggcactgc ttgacgctgc atgttggcac
     5461 ccatcaaggc acggttggag tcatcgtttt ccaagaaagg aatacatgct gtcgcaacgg
     5521 caactacttg tttaggtgat acgtccatgt agtctacttt atcaatagat acttctaagt
     5581 tttcactttg agcacgagcc ataacaacgt cttgagcaaa tgttccatct tcattcaatg
     5641 ggctgtttgc ttgggctacg atgtaatggt cttcgatatc agctgtcaag tagtcgattt
     5701 ggtcagtaac acgacctgtt tcacggtcta cacgacgata aggtgtttcg ataaatccga
     5761 atttatttac tttcgcataa ctggacaaac tattgatcaa cccgatgttt gggccttcag
     5821 gagtttcgat cggacacata cggccatagt gggagtagtg aacgtcacga acttcataac
     5881 cggcgcggtc acgagtcaat ccgccaggtc ctaaggctga aagacgacgt ttgtgtgtca
     5941 attcgccaag agggtttgtt tgatccatga actgtgacaa ctgagaagaa ccaaagaatt
     6001 ctttgatact tgccacaact ggacggatat tgatcaattg ttgaggtgtc aatgtttcag
     6061 tatcttggat cgacattctt tcacgaacca cacgttccat acgtgctagc ccgatacgga
     6121 attggttttg taaaagttca ccgactgaac ggatacgacg atttcctaag tggtcgatat
     6181 catcgacatt gccgatacct tccatcaagt tcaagaaata gctcattgaa gcaatgatgt
     6241 cggctggacg aaccgttttt acagctgctt ctggatagcc gtttccgatc acgtttactt
     6301 cacgttcagg gtctcttggt gaaaatactt tgatgacttg gacagtcatt ggatctgtga
     6361 ccacaccgtc ttctgatgga tagtaagtca ctgaatttag gccattatca atgaaaggag
     6421 ctagtgtttc catgacttgg tgagtcagaa ctgttccttt ttcaacgatg atctcgcctg
     6481 tttctggatc aactaatgtt tcagctaatg tcagattcaa tagacgtgtt ttcaaatcta
     6541 attttttgtt tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt ggatcgaaga
     6601 aacgagcatt cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct ggacgcaaac
     6661 gttcgtaaac gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt ttatgcaagt
     6721 ctttttcgac tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag atcgtatcat
     6781 cggaaccaaa tcctaacgca cgaactaata cggttaaagg aatcttacgt gtacggtcga
     6841 tacgtacata agagatgtct tttgcatcag tttccatttc tagccaagct ccacggttag
     6901 ggataacagt agaaccgaat ccttcttttc cgtttttgtc gacttttcca tggaaataga
     6961 cacctggtga acggactaac tgagaaacga ttactcgctc tgccccgttg atgatgaatg
     7021 ttccttgttc tgtcattaat gggaaatcac cgaagaatac ttcttgtgct ttgatttcgc
     7081 cagtctcgcg gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag tttgcatcat
     7141 gcgcacgagc ttctgctact gtatactttg gttctttcaa ttcataatct acaaattcca
     7201 aagatagatt gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt tctctaagtc
     7261 cctcatctaa gaaccattgg taagagtctg tttgaatttc gatcaaattt ggtaattcca
     7321 acacttcact gattcttgcg aaacttctac gttcgcgatg ttttccgtat tttactacgt
     7381 gtccagccaa gctcttcacc cctctaaaat gtcattcaaa aagactaccc gatcaattgt
     7441 tacaataata tttcaaatat tatttttagg taacaacaga cattttttgc ggcttttagg
     7501 caaaaaaaaa ccaaaaatag aacattctct tgaaacctta cttcgtgagc ttctactttt
     7561 gtttccttat attaaagccg aaacggacaa tatttcgttt ctgccttttc ttcatcagat
     7621 agtttttgca acttcatata ctacacttat tttctataaa agtcaacact tcctggcgtt
     7681 tcttctgctt tttcgcaaca ttttcttaat gttttcaatt ttatgttttc aattatctga
     7741 caattcttaa ttgacagacc tttttatctc ggttatactt tagaaaattc attttgtgga
     7801 ggaacttcta tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa taacttttac
     7861 tttagctact ttagataggt ttgtattcat catgatggat acaaacgtta aacgacagtt
     7921 tgtatctatg atggctaaag aactttgtat tgcagcaaaa agccacgtag acaaaatgct
     7981 aagtggctga gcagtgaaaa tacaaagtaa aagtatcaag cattctactt tttcaattta
     8041 ttttccgact tttcaatcca tttggacatt ttgtctgaat ggattttttg tttcccaaaa
     8101 ttaaggagga aaaagaaatg aaaaaaaata taatcatcgg attaggcgct gccctgctac
     8161 tagctttagg aggttgcgca caaaaagaca attccgcaga ggcatcagat ggacaaaaaa
     8221 caattggcgt attgcaactt gtacaacata actcgttaga tgctgcctat aaaggattca
     8281 aagaaggatt agcagaagaa gggtataaag aaggcgataa tctaacaatc gattatcaaa
     8341 atgcccaaaa caatcaagac aacctgaaaa gtatgagtga gaaactcgtc aaagaagatc
     8401 ctgatttgct acttggaatc gccactccag cagcacaatc tttattaaat gaaacaacca
     8461 ctatcccgat gactgtcaca gcggtcacag acttggaaca agcccattta gtcacatcca
     8521 atgaaaaacc tggcggcaat gtgactggca cgacagatat ggtgccaatc gaaaaacaaa
     8581 tcggcttact gttaaatatc gtgccagacg ccaaaacaat cggcatcatg tataacaacg
     8641 gtgaagcaaa ctctaagatc caagctgatt tggcagaaaa agaattgaaa aaagcgggcg
     8701 tcaaagtcaa agtactgaca gcaaattcca caaatgatgt ccaacaagtg acgaaaagtc
     8761 tagctaaaga tgtagatgga atctatattc ctactgataa cacgttcgca agtgcggcaa
     8821 gtgttgtcgg tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc gcagttgatc
     8881 aagtcaaaga cggcggtcta gcaacagtag gaatcgacta cgaaagcttg ggtaaacaaa
     8941 cagggatcat ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt cctgtcgaaa
     9001 cagcgaatga tttggaactg tatgtcaata aagacatggc caaagcatta ggcatcaatc
     9061 cagacagcat caaagaagct gaataaaaca caggaggatt ctcatgacaa atttgctctc
     9121 tcttttctta tcatctgcat cgcaaggggt cttatgggcc ctacttgcga ttggtgtata
     9181 cgtcactttc cgtatcttgg acattgccga cttgactgct gaaggaagct ttcctttagg
     9241 tgcagggatc gcggcagtaa gtattacaaa tggctatcat ccattgacag cttgtcttct
     9301 aggcttttta gggggtgcgg cagcagggct tgtttccgga ctgcttcaca caaaattgaa
     9361 aattcccgcc cttcttgcag ggatcatcac catgactggt ttatattctg tcacatcccg
     9421 tgtgatgggt gcgccgaaca tctctttatt gggtcagcca acgatctttc attgggtcga
     9481 gtcattcggc ataacaaaag acaacgctgt actgatcgtc ggtctgcttt ttgctttgat
     9541 cgttgtatgt ttacttgttt tgttcttacg tacagaaaca ggacttgcta ttcgtgcaac
     9601 tggcgataat ctggcaatga gcgaagcaaa cgggatcaac acagataata tgaagatcat
     9661 cggttatatg atttctaatg gatgcattgc tctttctggc tccttgcttg cgcaaaacaa
     9721 cggctttgct gatttaaatt ctggtattgg aacgatcgta attggacttg cttctattat
     9781 catcgcagaa gttttgttac gtaaccagcc actatttctc cgtctcttga ctgtcgtttt
     9841 aggtgcggtc atttatcgtt ttattttagc gttagtcttc gaactgaatg ttgaaccaag
     9901 tgattcgaaa cttgcttctg ctttcgtgct agtgatctgt ctttctttcc cgcagatcca
     9961 gcaaaaattc catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa tgacgtctta
    10021 acattggaaa atctccatca tacctttgaa aaaggaacga tcaacgaaaa tcatgtcctg
    10081 aaaggcatta atctttcctt agatcccggc gacttcgtga cgatcatcgg tggaaatggg
    10141 gctggtaaat ctactttgct gaacagcatc gccggtacat tttctgtcga tcagggtcaa
    10201 attttattga atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc gaaatccatc
    10261 agtcgcgtat tccaagatcc taaactaggg acagccgttc gtttaacggt agaagaaaat
    10321 cttgctcttg ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt caaaccacaa
    10381 gaccgaacat ttttcaaaga ccagctggtt cggctaaatt tggggttgga aaatcgttta
    10441 tcctcagaaa tcggtttgct gtctggagga caacgtcaag ctattacgtt attgatggcc
    10501 acattacagc gtccagaact gatcttatta gatgaacaca ctgcagcgct tgaccctgct
    10561 acttccaaaa cggtgatgga attgacagaa aagctgatca ctgagcagaa tctcactgct
    10621 tttatggtca ctcatgacat ggaagacgcg atccgctatg ggagtcgact gatcatgctg
    10681 catcaaggaa ggatcgtcgt agatatccag caagaggaaa aacagcagct cacagtgccc
    10741 caattattag cgttgttcaa acaaaacagc ggcacggcat taaaagacga tcaagtactt
    10801 ttatcttcat aatcagaaag aggatgggac aaaaaatgaa cgcccaccct cttctttttt
    10861 ctctttcctt ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga aaactatttt
    10921 gttctctcct tcttcctgat agaatggatg ggaaaggagc ttgatgccat gacaacgaaa
    10981 gacaaggtac ttcaattatt gaaaaagaca ccagattttc tttccggaga aaagttggca
    11041 cagcaactgg aagtttcccg gacaagtatt tggaaagcca tcaaagaatt ggaaaaggca
    11101 ggctatcgtt ttgagcacgg gcctacaggg tatcgttacc tgccctctga cgtactagat
    11161 gcaaaagaaa tccagcaaga gctacggtcg tttattcctg atttgaaagt acaaacgatg
    11221 ttgacttctg aatctacgat gaaagatgtc aaactggcag cagctcaagg agattctgtt
    11281 tcgaagttat ttgttgctga tacacaagaa caagctcgtg gacgttttgg acggcctttt
    11341 ttcgctgaac ctggacgagg aatctacatg agtctcttgc tccatccaga caaacggttt
    11401 gatgaattgc ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc cattgaatct
    11461 gtaaccggtc gttctgcttc gatcaaatgg gtcaatgata tctacatgga tggaaaaaaa
    11521 gtctgtggga ttttatctga agcagtcagt gatatggaaa gcggcaggat cagtcatatc
    11581 atcattggga tcgggcttaa tttttctgtt cctcaaaatc attttccagc tgatctccaa
    11641 gaaaaagcca tctctgtctt tcccgacgga caagctagtg tcacaaggaa tcagctaatc
    11701 agcaaaatct ggcaagaatt gttcacttat ctttctcacc cagaaaaagc gttggacttc
    11761 tataaagaaa aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa aggaacgact
    11821 tatgtcggtc ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca aacaaatgaa
    11881 cagaagatga gtttgtcttc tggcgaaatc agtctcacat ctatccgtac gcaataatta
    11941 tcagatttca caaaaggaca cctgatctca tacagtgtcc ttttttctga attctcttca
    12001 aaagactctc cttattctat cagctgacag tttctctatc ctctagaaaa aggtattcta
    12061 aaaatatcta taaagcatgg tacactttct ttaaatgaat caatgcaaaa aacaagagag
    12121 tcatcagttt acacgatcaa aagagatagc aggccgcttc ctttttcaat cttatagata
    12181 gaccatgggt aacgataaaa acaaaaaaga acttgcgact tattttgccg taagttcttt
    12241 tttagctagt gccttaatct cttaatccca acaaacgtct cgcatagatc acctgaccag
    12301 agtgcatagc agcatcatca ataatagaaa cgagacgcat tcctcgtgtg actggtggtg
    12361 tccagttctc gtcaattact tcatctagct cggaaggttc cagccttctt aagtaagaaa
    12421 tagcaaaatc agcagctcct cgcaagtatc ctagcagatc ttctatttga ttagcttgga
    12481 tctgctttgc ttgttccaga ctatgcttcc aatcttgttc gttatctgct atcgtcatcg
    12541 gaaaccggct ttcccagtct tgactatgcc aaattggaga agttcctgct aaatcagcaa
    12601 tctggaaatc taattctcga gcggtatgcc aagccagcca agtcattgat ttgatctgcg
    12661 gggctctatc ttccactgga aaacgattgg cctcctcaat agagacgcct tcaaacaaac
    12721 gttcaaaccg atcgtatgcc cgatccacac tctcgcatag catatctaaa taatccattt
    12781 attttcctcc tttttattta tcctacttac tttttcctaa ttctaggata cctacttata
    12841 tgttactaca cacccttatt ttttacactt taacagtcac catcatcaat agtttggaga
    12901 ttgaaagaaa aagatagtgt cgaactatca attgaacaag aagcaacaat atgaacgttt
    12961 cattaatatt ctttaaataa acaatgattt ttcaaacgaa cagtttaaga ctaggagaaa
    13021 aagagtataa taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa aaaagggcaa
    13081 gtttactagt cctagttgct ttgttgttca atatcttttc gtatggtgtg gccgtttcag
    13141 cggaaacata cattcctaaa gaccctggga atatttataa tgatctaact ggtaactatg
    13201 gcttgttagg aattgctagt caattccacg tatttgctaa aaataagaca actgtgaatg
    13261 cacatacaga cggaaatata gcaacacatg aacttgatgc aaaaaataat tttggtacag
    13321 agcttcatga aggtttattg aaccaagaaa taaattatat acaaaaaact gattctttcg
    13381 ctaattcttc aggcatacct acaggtagca caagaatgaa taaatttgtc gttggcagta
    13441 acgtggatgt agcacttcaa gatggtcatc ctacagtcaa tggatccagg cttgatcact
    13501 taactccaga tgatttttat aaagatcgtg ctgggcatga atatattgat ttcgagcagg
    13561 aatttgctaa attgaatgta gcagcaaatg atcttgcaac gatcactcca gctaaaacat
    13621 atactgctgc agattttcca gacatgaaca atcggacaat cgatttaact gatttatcag
    13681 ataccgggtt tttattggta aatatcgatg cagaagtgtt aacgatgaat acgccacttc
    13741 aaatcattaa tccaaatgat caagtagttg tatttaatgt catcaacagt tcttctgcat
    13801 tgaacgtaca gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca gaagattttt
    13861 cggatgcgaa tatctcttgg aattttggaa atgagatgac tgatttgaca atcagtgctc
    13921 cttttcaagg aacaatcctt gcgcctaatg ctactatccg cattactcaa aaccaagacg
    13981 gaacgattat aggaacaaat gtgattttag atgcagctac caatcgttgg gatcctaacg
    14041 aaatatttat cagcgacaat ggtacagata cgacagacac aagcgacagt acagatacat
    14101 ctaccacaag tgatagctca gattcatcaa cttcaagcga cagtacagat actacctcta
    14161 ccacaagtga tagcacggat acatcagctt caagcgacag tacagatact acctctacca
    14221 caagtgatag cacggacaca tcagcttcaa gtgacagtac agatactacc tctaccacaa
//
LOCUS       DAFLVO010000071        14130 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.071, whole genome shotgun sequence.
ACCESSION   DAFLVO010000071 DAFLVO010000000
VERSION     DAFLVO010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14130
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.071"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..244)
                     /locus_tag="L1U99_002266"
     CDS             complement(<1..244)
                     /locus_tag="L1U99_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBN1212794.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELI"
     gene            complement(237..1829)
                     /locus_tag="L1U99_002267"
     CDS             complement(237..1829)
                     /locus_tag="L1U99_002267"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBN1212795.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(2339..3064)
                     /locus_tag="L1U99_002268"
     CDS             complement(2339..3064)
                     /locus_tag="L1U99_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212796.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(3218..3544)
                     /locus_tag="L1U99_002269"
     CDS             complement(3218..3544)
                     /locus_tag="L1U99_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212797.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(3581..3946)
                     /locus_tag="L1U99_002270"
     CDS             complement(3581..3946)
                     /locus_tag="L1U99_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBN1212798.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(3983..4198)
                     /locus_tag="L1U99_002271"
     CDS             complement(3983..4198)
                     /locus_tag="L1U99_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1212799.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            4327..4662
                     /locus_tag="L1U99_002272"
     CDS             4327..4662
                     /locus_tag="L1U99_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1212800.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(4738..6735)
                     /locus_tag="L1U99_002273"
     CDS             complement(4738..6735)
                     /locus_tag="L1U99_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212801.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(6833..7108)
                     /locus_tag="L1U99_002274"
     CDS             complement(6833..7108)
                     /locus_tag="L1U99_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1212802.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            7340..8074
                     /locus_tag="L1U99_002275"
     CDS             7340..8074
                     /locus_tag="L1U99_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1212803.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            8113..9255
                     /locus_tag="L1U99_002276"
     CDS             8113..9255
                     /locus_tag="L1U99_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1212804.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(9883..10368)
                     /locus_tag="L1U99_002277"
     CDS             complement(9883..10368)
                     /locus_tag="L1U99_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HBN1212805.1"
                     /translation="MVRRVFFSFHYADVTRAMVVRNSWTLRGTKEAGFVDKAEFEKVK
                     RNGDIAIKNWIDNQLIGTSVTVVLIGKETLDREYVKYEIQESYKRGNAILAVNIGKIK
                     DFNQMTTTSQSVIKIIGQKPDGEYLWFDEIIDGQYDYISDDGYNNLGTWIDSAAYKKG
                     K"
     gene            complement(10370..11134)
                     /locus_tag="L1U99_002278"
                     /pseudo
     CDS             complement(10370..11134)
                     /locus_tag="L1U99_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(11304..12497)
                     /locus_tag="L1U99_002279"
     CDS             complement(11304..12497)
                     /locus_tag="L1U99_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1212806.1"
                     /translation="MSEKRRDSKNRVLRSGESQRKDGRYAYKYVDTFGKPQFVYSWKL
                     VPTDKTPAGKREDISLREKEKEIQKDLDDGIDTIGKKMTVCQLYAKQIRHRGNVKHNT
                     KLGRERLMRILEQDRLGSCPIDSVKLSDAKEWALRMKEKGLSYKTINNDKRSLKAAFY
                     TAIQDDCIRKNPFDFQLSDVLDDDTEPKVPLTPAQEESFLSFIQGDKVYQKHYDAIVI
                     LLGTGLRISELCGLTDKDLDFENRVIIVSHQLLRNTGVGYYIDEPKTQSGVRKIPMNE
                     EVYQAFQRVIKNRKGAKPFIIDGYANFLFLKQNGYPMTAVDYGGMFGRLVKKYNKSHE
                     EALPKTTTPHAMRHTFCTRLANAGMNPKALQYIMGHSNITMTLNYYAHATFDSARAEM
                     ERLAA"
     gene            complement(12581..12781)
                     /locus_tag="L1U99_002280"
     CDS             complement(12581..12781)
                     /locus_tag="L1U99_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBN1212807.1"
                     /translation="MNHDVPIWEKYTLTIEEASKYFRIGENKLRKLAEENPASGWVIM
                     NGNRIQIKRKQFEKIIDTLDTI"
     gene            complement(13205..13438)
                     /locus_tag="L1U99_002281"
     CDS             complement(13205..13438)
                     /locus_tag="L1U99_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1212808.1"
                     /translation="MKNPNYKGIELLPLSVIEAARAGDAGAVERVLQYYSGYMNKLCT
                     RTLYDENGYPHVCLDEAMKRRLEIKLIHAIVTN"
     gene            complement(13445..13876)
                     /locus_tag="L1U99_002282"
     CDS             complement(13445..13876)
                     /locus_tag="L1U99_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1212809.1"
                     /translation="MDAIPRDYEARCMFDAFCKTVLRNEAKSYLAEMKRRRDREVSLS
                     SLSQADLDKLCTVDHYPSDSFTFSSHGYDLHINNELVAEAFAALPSMEQSILILHCVL
                     DMADGEIGGLVGMSRSAVQRHRTNTLSELRKQLKALMPKGG"
BASE COUNT         4295 a         2895 c         2270 g         4670 t
ORIGIN      
        1 tgattaattc attatatttt ttttcagtaa ttttatatct tgtttcgtaa ttatcataaa
       61 tagcattttg ttgttcatag acaacaaaat tgctattaga tacaaagaat tctttcttta
      121 aggcactccc aaatggtccc ctccttactc catctttttt atcaagtaag cattcaaact
      181 tacgctgttc ccaagcttcc gtaaatcctg ggaaacgaat ttctggttgt atatcattac
      241 tcatgtttga acacctccag cgcaccttgt aaccacgctt cattttcagg tgttgtttgc
      301 agggaagaga tagcttctaa aagttctttt tctagcactt gctgttcttg tcgtatcttc
      361 ttgatgtcat ttccgacatg aaccatatca attggttctt cttcttcaaa cgtatctaca
      421 tagcgtggaa tatttaagtt atagtcattt tctttgattt catcaaagtt tgccaaatga
      481 gcgtatttct cgacatcttt tctttcagca taggtttcga ggattttttg aatgttttct
      541 tccgataatt tattctgatt ttttcctttg acaaattctc gactagcgtc aatgaataat
      601 acgtctcgag tttggcggtt ctttttcaat acaatcaccg tcgttggaat cgatgtcccg
      661 aagaacaagt tcgcaggcat accgatcaca gcataaatac tgccgtcttc tagtaatttt
      721 tgacgaatga ccccttctgc agcgccacgg aataaaactc cgtgtggcaa gacgatggcc
      781 atagtccctg tttccttcaa atgatagaaa ccatgaagaa gaaacgcaaa atctgctttg
      841 gattttggcg ctaattttcc ataacgatta aaccgagaat cgtctaagaa ggtcgtatct
      901 gctgaccaat tagccgaata aggtgggttc attactactg catcaaatgt gtaaggttca
      961 tctgttggcc aatccttatt caacgtatcc ccattgcgga gattcatttc ttcggcatct
     1021 accccatgta aaatcaagtt catttttgct agattgtatg tcgttgtatt taattcttgc
     1081 ccatgatatt taacgttatc tgggtgagtt aagtagttac gcacatttaa catcaatgaa
     1141 cctgaaccca tggttggatc aaaaacacta aagaatcgtc gttctttttg atccaacgtc
     1201 acgatttgtg ccatcatatc agaaaccata tgaggcgtgt aaaattctcc ggctttcttc
     1261 cctgcttctg aagcaaattg actgatcaga aattcataag catccccgat cacgtcccca
     1321 tcgtgaccta aaacttccac gtcattcaat ttcttaatga cttcggtaat cgtcacattt
     1381 cgttgttgct catctgttcc tagttttttt gattggagat ccacatcatc aaataaccca
     1441 ttaaattgat tgtaggtaga tgccaattgc acaaaggctt tgtttagatc attcaattgg
     1501 aacgttgctt gttttgcttg atccgctaag acgttgaaaa gatactctgg cgaaatcgca
     1561 taccccaaaa tatcaacgat tgttgcaatc agatcttctt ttgattcttc atctgaaagt
     1621 aattcgcgat acaacatcgt ttgtttgctt accgtatcat attcctctaa ggattcatct
     1681 gctaaaagaa ccacttgttc caacaaacgg tcggataaat atttatagaa aatcagtccc
     1741 aataaataat ttttatattc tgacgcatcc attttgctac ggagattatc tgccgcacta
     1801 aataattttt gatttaattc tgcacccaaa aagatacact cctatctctt atttaaagtt
     1861 gctatatacc ctcttatttt agcatactcc cttttagaaa aagcaaaaaa aaaaagaaag
     1921 aaacttattc ttgctaataa actacgcgaa aggagtctaa cgttgtttga tataacttag
     1981 actgatcgtt aacttatttt ttatatttct acatagttat ctttagaacc atttcagata
     2041 catatgaaac aattacatat gattttttca taaaaaaaca gtactgtcta gtagtataaa
     2101 atatacaaat ttcttaaaaa ttttttcact aaaatcacta cctgaaacag tctaaaacac
     2161 ttatatatca acgtttaatg aaactatctc cgtttcattt cagatacaaa taaatatagt
     2221 cgggctccaa atccgaaaaa aaataccccc agtagcttat cctaagctac tggagatgta
     2281 taagtacggt catataacaa cggggtaggg taaataaatg aaaaagatgg aagaatcatt
     2341 attcaataac ttttttaaat acttcgttgt aatcagttac ctgtccgttc ttaaatacca
     2401 cagaataatc ttttttccca ttttcaagta accgaagtgg aatatcttta ccaactttct
     2461 ctgtcactgc attactgata cctgttagat tagctaataa atctgataaa gattgagcat
     2521 ctgtagaaat ctctgtatca gtatttatcg tgattccttt atcttcattt acaagtttcc
     2581 aagtaggtgg tatagctgtg tatgtttcta caaatgaatt aagtttttca ttaagtgact
     2641 tctcttttat atttccatct aaaaactctg tatatatggc ttgagctata ctaaaacaaa
     2701 gctggccttg ttctaataat tttacatcat tagttagtaa agctgtgttc acgttatcaa
     2761 tcgcttcaag aagagtatct ttggtgtccc taacagcttt aggtgtgcct tctggaattt
     2821 ccctacttga tacctcgtcc attttatctt ccataaaccc cttaaaatca tatctttctc
     2881 ccaaatccat agaagttttt gagaaagctt tcatttctga gtctatttct tcaataatat
     2941 ttaacatgtc tgatacatat tgtttaggct gattcgtttt taatctatat gtggtaaata
     3001 tctcaattcc tccaattatc aataaaattg ccaaacaaat ccataataat tttttctttt
     3061 tcatttttcc tcctatacac tgctgttata acagtgacta atgtaaagat tttcccagca
     3121 atcatcagac tattatttac agggaatcaa aaaaactcct tagtaagctt acacctttag
     3181 gagttcctgt ttgaacggta tgcataatac atttaaatca atttaacatt aacacctcag
     3241 tatatggtat ctctacatat acacggtctt tttttggata gtactcgaca tttatattga
     3301 tagcacttcc attgtctaac gtagctttag cccggtacgt gttatcacca ttatcatgag
     3361 tgatcgtcac atcatcacat gtccgattta agttatactg ttcttgtaaa atctgagtta
     3421 ccaatggtac agatgacttc tctagtccag atgaacccgt cattcttgaa aaaattatac
     3481 ctataatagc caatacaacg atacctataa tgacaaactt cttattcata tttactttat
     3541 tcaacttttt atctcctatc tccaaaatga ttttctctca tcagtaactc attgacatcc
     3601 ccaatagtac accaaagatg gctccagcta cccctgctat catcaaaatc gtacccattt
     3661 gttcatcttt ctctcgatat aagtaaccca taataacagc aacagcacca aataccacag
     3721 gaataaatgc taatgatact accatagaaa tccaaccaat aatcaaatac agcttccctg
     3781 tctcttgtcc atgtacgatt tgttccttca tttcattaat tgtctgctca gtacttttct
     3841 ttactgtgtc tgttccggtt gtctcatctg tttcttgtaa tgctccgcaa aactggcaat
     3901 acttactttc atttgttatt tctttaccac attttctaca atacatgtct tctcctccta
     3961 aaatcattca attgcttatt agctaactgt ttactttatt aaatacatca gaaaacagct
     4021 catttattgg tacacttaat atctcagaaa gcattttcat ttgatagggt ttaggaatcg
     4081 ttctccctgt ttgccacgaa cttacacatt gctgtgtaac attcattttt ttggctaact
     4141 cagtttggga aagtcctttt tcttttctgt atcggctgag attacttact tttttcatga
     4201 ttctcccctc ctgttttatt atatacaaca atatgatgta tttcaactca taaaatatat
     4261 aaatacttca aatgtcatta caaatacaac aacttgttgt actctactga gaaggggggt
     4321 gtattaatga aacagaagca atatgcaaag gtcattagag aaaagcgaaa agcactcggg
     4381 tggacacaaa aagaattagc taaaaaaatc ttctctacac aacaggcagt agcaagatgg
     4441 gaaaattctg taacagaacc taacctcgat agcttaacag ctctttctag agccctagga
     4501 acccctgtaa gccattttct agacaatgtt gacatagatt atgaggaaga gtttttggct
     4561 ctctatcgct ctcttagtac tgaagatgca attcgaacaa ttgactatat gaagctatta
     4621 aaaaggcaag aaaatgaacg caatcagcta ttgaaagatt gaaaaataaa taacccaccg
     4681 aactttaacg gtgggtgtat tgagatgaaa taagattaag agctatggat aacctgtcta
     4741 gtttaatata attgggtctc ttctattcct tactctccgt ccatcatctc ttgttacact
     4801 tgtaaattga taaataggaa ctaattcaac tcctgataat atcaattctt ttattacttc
     4861 atctatccct gcccctttcg ctagatatac taaaaaacta ctgcttgctt tcacattgta
     4921 tagtttctta atatccttag aagctcgttc aagagtgaat ccttgtttaa caaagtagcc
     4981 tctgttttct attaaagcat ttttcacgct gttatccctg acatttcgta ggcgttcaca
     5041 aacagtgtta ataagttctt tttctgtcat tagatatgtc ccttgccacg ataagccctg
     5101 taaaacttca tgtgcttcat ctaaaatcaa ttgtttttcc ttgctaagtt ctgatcggga
     5161 attttgagga aatactcttt tagcctcttt ttcgttaaaa catatcttaa cccattcata
     5221 agaaaaatat tgatatgtaa aatgaaattt ttccagaagt ggaaggatat cttcattcaa
     5281 tttttgaatc acagaagttg cattaaaaac gtctaatcga tagacattgc ttctcttatg
     5341 tttaaagttt cctaacgctt tctcttcctt taacctattt aggtattcga gcatcttcaa
     5401 aggaacatct tcatcatcta atttttttat caatcctata aaagtcataa gtgatagtaa
     5461 cttattacat ttatctatgt cataagtttt accatagtaa gaactcattt ttttagctaa
     5521 ttgttccccc gacaaaatac aagtcacact ttccttacta tcatcaaaaa aattaacatc
     5581 agaaagcaag acatcataga cacgtcgcat ttcctctaga taattcctta ttgtcctgaa
     5641 aagtttgtct ttcattgatt caagagtgtc aaaaagtact tttgattcct ctttcaattt
     5701 tcgaaaatgt gtaggataca agtctaggtt ctctaatagc caattaaatg tttctacccg
     5761 actgtctttc tttaaaatta gcatcacaac tccaataaaa ttttcactga tatcacaatt
     5821 actggaatga caataaaaaa tggaatgccc agttttactg gtaaaaatac tagcagaggg
     5881 attatgatcg ttgtgaaaca gacatcttaa gtttttactt gacttaagta atttattcat
     5941 atcaatggtt aacaatcttt cataaatctc attaaaagac atgtcggagg aatcaaacag
     6001 gcagtcttta aaccactgtt tcatttcttc tttgtcgtca ttttttatca acttaacaaa
     6061 atcggtttca ttgactagtt catactctct ccctgaatca ctttgacaat ttttagaaca
     6121 tgtcatggta aaatcaatcg gaagctcagt aatatctaac atgttgtctt cattaattat
     6181 tatcactgca tctgacttat atcctccaaa aaacattcta ttcgaagcat ttacattgtc
     6241 atcacacccg gggatgttct ttttcaagta ttcgtaaaca gcaaccattt taccatagtc
     6301 agtaattgct tcttttaata gaaagacaat cttgtatttt tctagatttt cagagtaccg
     6361 aatacttttt tgtatcgcaa acgcagaatt atgaactaaa ttgatagata aaaccttttc
     6421 tatgcttaag tatctactat catctttact caaatctact accttcccct tctcatcttt
     6481 aacagtgtta tcgacatcca gaataattac tctggtttcc acaaaactct ccttgtcatt
     6541 gcctttattc tttgtcttgc ttggaataaa tgattgtgat gaatttagta tctctacaaa
     6601 ctcatctctt gtaacttctc tatagttatc taaacaccta tctcttacat cagttttttc
     6661 tttttttgta actggcttct ctaataattt ttctttatct acataaattg gaatattaat
     6721 cattgatgtt tccatttgtg tttcctcctt ataaaattct gttaaagact aaaacataca
     6781 gataataaaa acaaactctt tattactata tgttttagtc ttatttgttt actcaacctt
     6841 tataccgttc catgaaacta tcaatatcag attttttaaa tctaatgacc gtatcaattt
     6901 ttataacagg taacccgtat tgagaaacat attttctaat cgttcctact gatacaccta
     6961 gatattcact tgcctgctga tagtccatat actctagagt gactccagaa ataatgtctt
     7021 ctagcatagg ctttagcact gtaattatct ctttcacttg ttgttcaact tgtatagaaa
     7081 caatgctatc aatgatttgt agagacatat ttccccctcc tttcgtgatt gcttgaacaa
     7141 attttctaag aattatcttc gtattttttg ctcaaaataa aagtattttg ttattaaccg
     7201 attaatcaaa caaaaaatga ttaccagttc atcgacatac acataatacc tcgataaaaa
     7261 aggggtgtca atagttttgt aaaatttatt tacaacaccc cttttttgag gtatactaat
     7321 tttaggaggt gtggtcaata tgataaaacg tccaccaata aattatttag aacgaaaaaa
     7381 gatactcgga acaaaaataa aagctataag aaagagtaaa aaattaacac aaccagcatt
     7441 tggtcttatg attaacaacg gtcaattaat tgacaaaaag actatctacg aatgggagaa
     7501 gggaacctat ttaccaatac cagagcgatt atcccgaatt gctgatttgg gaaatatgag
     7561 tatagaggag ttagtttgtg gcaatgtaga agaatatatt ttgggaatta ttctttatag
     7621 agatagcatt gtactagatg gtataacatt tccagataaa aacctgttcc agcatcttcg
     7681 tcaacagttc ccaccagtac actctaattt agatacatgg ctggatagat attccaaatt
     7741 agaaccagag atgcaagaat ttattgctaa caagacttgt aataaagtta aaaatgaaaa
     7801 aattagtctt ttcaatatct taaaaataga agaattattc atcaatgcta ttgtagaaga
     7861 atttgacaat aacattcttt tcctcactag cagtatagaa gaactactag aaagaatggt
     7921 agatgaatgg ctacctattc aattgaaaga catgtcttat cccgaagaag ctgtgagaga
     7981 aattactgat aatataaaca agctagaaca aacgatttca tcaattggga aaaaatacac
     8041 taagaaaaaa atgaagggag gtgataccat ctagtggtaa gtactccttg taaactaaga
     8101 ggagatgatt tcatggcaaa aatatcaaag tacaaaaaga aaaacggtca agtggcgtgg
     8161 atgtataaag gacacattgc caccgatcca cgaactggtg aaaaaataaa tactacgaga
     8221 agaggtttta gtagcaaaca agaagctcaa aaagattatg acgagtacag acatcaaata
     8281 ttatacggtg ttaaaaagaa agcacctgat atgacatttg aagacctgta taatgaatgg
     8341 ataactcatc agcgtaccag tgttaaagct tcaacaatcg caatctcagt aagatacgca
     8401 aataatcaaa tacttccagc atttggtaag cttaaactat cgaatatctc tgtcccatat
     8461 tgtcaaaaag tggtagatga atggcacagt aaatatgaaa gttacgatta tatgagaaaa
     8521 cagactgcac aaattttacg ctacggggtt gcaatgcaat atattgacaa taatcctatg
     8581 gaaaaaacac ttcttccacg aaaaaaagag tatgagaaaa atcgtaaatt ttactcaaaa
     8641 gaggagctta ataatttact ggatgctttt aaagattttg gtaacatgaa acaatacgcc
     8701 ttcttcagat tattggcata cacaggtatg agaaagagtg aagtactcgc tttacagtgg
     8761 aaagacatag acacgtttaa taaagaacta catgtcaata aaactcttgc tgtagatgaa
     8821 tttggtaaag ttataattca atctccgaaa acaagagctt ctagacgagt tatctcttta
     8881 gatactgaga ctctttctat cctcaacaac tggaaattac agcaaaaaga agagtattta
     8941 aaacttggat acaatactag ctctaaagag caacatgttt ttacaacagt taaaaacact
     9001 ctatacattc caaacactgt taatgattgg ttaagatata ttttgaaaaa atataacttg
     9061 cctcgtatta cacctcatgg gtttagacat acacatgcta gtttattatt agaagcagga
     9121 gaatctgtca aggtagttca acaacgatta gggcatgaaa atagtaaagt gacattagac
     9181 atctatgcac atattacaaa taatgcacct aagaaaacag gtcaagactt tgctgatatg
     9241 atggctcatc agtaaaagag ctggtcaaaa tctggtcatt tctagtatac aggcaaaaca
     9301 aaaaagctag aacccttata tatcaagggt tctagctcct ataacaggtt tacccaacac
     9361 tgccttccaa tgactctttt gggaatcaga ggaaagaatc aggctttata gagatatttc
     9421 atctaacaaa ttactttaga ctgacagtat atatcagcag gtactgtcat cgggaacgta
     9481 gccaatatcg tatccaaaac agcaggtaga gaagctattt gaggattcaa gttattctat
     9541 ttcaaccatg aagttaagtt cattaaaaat aaagatagtt ggtatttcaa taatttttgt
     9601 atagagttaa tcactttatt gatgctaatt catcttgatt ggtattataa tcgtattcaa
     9661 gttgcgtggc gtgcttttgc tagaaaatat ataactgttc tttataaaga aatataagga
     9721 ttaaacattt tttatcatag agttttactt atctatagaa ttatgtctgt tcctaattca
     9781 gtttgatgaa ttaactgata aaaaaatatc tactatttaa agatacaggg ataagtaagt
     9841 aaaaaaataa catgtcatta gatagtagac agttccaact ctttatttac cttttttgta
     9901 tgctgcactg tcaatccaag ttcctaaatt gttgtatcca tcatcactta tataatcata
     9961 ttggccatca ataatttcgt caaaccacaa atattctcca tctggttttt gcccaattat
    10021 tttaattact gattgactag tagttgtcat ctggttaaaa tcttttattt tacctatatt
    10081 aacggccaaa atagcatttc ctcgcttata actctcctgg atttcatatt taacatattc
    10141 tcgatcaaga gtttctttac ctatcagcac cacagtcact gatgttccaa ttaattgatt
    10201 atctatccag ttttttatag caatatctcc attacgttta actttctcaa attcagcctt
    10261 atctacaaaa ccagcttcct ttgttcctcg caaagtccag ctgtttctaa ctaccattgc
    10321 tcttgttaca tctgcataat ggaaactaaa aaaaaccctt ctcaccatat taatcctcct
    10381 gaatactatt tattaaactg acaatttgtt caactttttt atctacttct ccttcagtat
    10441 ctaatttttc tagcgcttga aatttacttt ttaaggaatc atcaaaataa tcactgaaat
    10501 tctcttgaat cttatcaaac aaaaccttac ttgcaccttt ggtaaatcca atcggaacta
    10561 ctatattttc attttgaaca gataattcaa attcttcaat cattccatct gctgtaacta
    10621 tttcacctga ttcaagtttg tttccaaaaa caaaaatact aatcccagac tctgcaataa
    10681 tgttttctcg atatcttctc cactcatgag gcatatcaag gggaagtggt cttaaagaaa
    10741 gtacgtcttg tatgttattt tttcttaaat ttcttctctg ctttagaact cctgaaacaa
    10801 tactattacc aattccaagt ccgtaacctg atactattct ataaccggat tcagaaagcc
    10861 tatatgctaa tttctcgaca aattttaatc ctttcgattc agatgtaaat ggagtataat
    10921 caacagcact tcccgaaata aaaatagttt ttctcaaata cttttttcta atacttttca
    10981 aaatatcagt aatctcagaa taatcatcta cttcaacaac gtttatcgaa aatctggaca
    11041 aatcattgat ttgtagtctt ctttttgtca gttcataatt atatctctct tgatcaaaaa
    11101 aatcctcaga atcgacaaaa ttttccttta aaattatatg ggattttaga ttatcttttt
    11161 agaagttctt gaatgtcggt atagcccgtg tttccgggct tttccggcat ttttgatatt
    11221 gttagatact tacaaatgtt cttattacct ctcaccattt ccccctcaaa agtagtaaat
    11281 ggagtagtaa aaccggcctt gtgtcaggct gccagccgtt ccatttctgc ccttgcggaa
    11341 tcgaatgtgg cgtgtgcata atagttcagc gtcatggtga tattggaatg tcccataatg
    11401 tactgcaagg ctttggggtt cattcccgca ttggctaacc gggtgcagaa tgtatgacgc
    11461 atagcatggg gcgtcgtcgt tttcggcaac gcttcttcat ggctcttgtt gtacttcttc
    11521 acaagcctgc caaacatccc gccataatct accgccgtca tgggatagcc gttctgtttg
    11581 agaaacagga aattggcata cccgtcaata atgaacggct ttgcaccttt gcggtttttt
    11641 atcactcgct ggaacgcctg atacacttcc tcattcatgg ggatttttct gacgccgctt
    11701 tgggtcttgg gttcgtcaat atagtaaccg acgccggtat ttctcaaaag ctggtggctc
    11761 acgatgatta cccggttttc aaaatccaaa tctttgtccg tcagtccgca cagttccgaa
    11821 atgcgaagcc ctgtccccag cagaataacg attgcgtcat aatgcttttg gtaaacctta
    11881 tcaccttgaa taaaggacag aaaactttct tcctgtgctg gtgtaagagg cacctttggt
    11941 tccgtatcgt cgtccagaac gtcactaagc tggaagtcaa acgggttttt tcggatgcaa
    12001 tcgtcctgta tggcggtgta aaaagccgct ttcagggaac gcttgtcgtt attgatggtc
    12061 ttataagaaa ggcccttttc tttcatccga agcgcccatt cctttgcgtc ggacagcttc
    12121 acactgtcaa tcgggcagct ccccagccga tcttgttcca gaatacgcat cagccgttcc
    12181 cggcccagtt tggtgttgtg cttcacattg ccccggtgcc tgatctgctt ggcgtagagc
    12241 tggcagacgg tcattttctt gccgatggtg tctatcccgt cgtcaaggtc tttctggatt
    12301 tctttctcct tttcccggag tgaaatatcc tcccgtttac ctgccggggt cttatccgta
    12361 ggcactaact tccatgagta aacaaactgc ggttttccaa aggtatcaac atatttgtaa
    12421 gcatatcgtc cgtcttttct ctggctctct ccagaccgca aaacgcgatt tttgctgtct
    12481 cgtctttttt ctgacatctc gtcatgctcc tttccatgac ggaaagagcc gcatatatgc
    12541 ttataaatta ttataacata tctgcggccc tttttcacta ttagattgtg tccaaagtgt
    12601 caattatttt ctcaaactgc ttgcgtttga tctggatgcg gttgccattc ataatgaccc
    12661 agccagaggc cggattttcc tcggccagct tacgcaattt gttttctccg atacggaaat
    12721 atttagacgc ttcctcaatc gtcagcgtgt atttttccca aataggcaca tcatggttca
    12781 taatgcagcc ccctttcaca aattcaaagg tttgtgtgat ttaggggcat agacggacgg
    12841 ctgctggcac agctccacgg gactttcacc cccgcgtggt tctcacgcgg ccctacccat
    12901 tgcctgcgac gcttttaacg ctcggactgt ggctataagg gagtatcata gtcctgcctg
    12961 tacgtcgtcg cccgcaagcc gccacgctca cattgcggcg tggtgttcct cgctccgctt
    13021 ttcccgtagg gaaaagtatc atggcgcacc agccgtccgg ctcggcacag acagaatgtg
    13081 tccgtatgcc ctatgatgcg ccgccgttat cttgcgggca tatttatcaa ggtgcgatca
    13141 ggccaccggg aaaacaccga aacggggaaa gggtaagccg tttcatgctg ccggggccgg
    13201 ttcgtcagtt cgtgacgata gcgtggatga gcttgatttc cagacggcgc ttcatggcct
    13261 cgtccagaca cacatgcgga tagccgtttt cgtcatagag cgtccgggta cacagcttgt
    13321 tcatgtaacc gctgtaatac tgcaaaacgc gctctacggc tccggcatcc ccagcgcggg
    13381 cggcctcgat caccgaaagg ggcaaaagct caatgccctt gtagttcggg ttcttcatcc
    13441 gcgtctaacc tcccttcggc atcaacgcct ttagctgttt ccgcagctcc gataaggtat
    13501 ttgtcctgtg ccgctgaacg gcactccggg acattcccac aaggccgccg atctcaccat
    13561 ctgccatatc cagaacacag tgcaggatta aaatactctg ctccatgctg ggcagcgcgg
    13621 caaaggcttc ggcaacaagc tcattgttga tatgtaggtc atagccatgc gacgaaaacg
    13681 taaagctgtc gctggggtag tgatctactg tacagagctt gtccaaatct gcctgtgaca
    13741 aagagcttag tgacacttca cggtcacggc ggcgcttcat ttcagccaag tagcttttgg
    13801 cctcgttacg cagtaccgtc ttgcaaaaag catcgaacat gcaccgcgct tcatagtcgc
    13861 gggggatagc atccatcttc tcaccccctt tctgtggggg acttaggtgg ttctctccct
    13921 ttccgctaac aagactttga caaggccgcc agctacccgc taaatacctc ctttttgaaa
    13981 atttctcaaa aaattttttt ggggacagcc gggccgcaaa agacgacaaa aatcgcccgg
    14041 caggtcgcaa acctaccggg cgagaaaatg ctttgctatg ctgctgattt acatggtata
    14101 gtacatactc ataaccggaa tagccctgtg
//
LOCUS       DAFLVO010000072        13890 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.072, whole genome shotgun sequence.
ACCESSION   DAFLVO010000072 DAFLVO010000000
VERSION     DAFLVO010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13890
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.072"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            165..2330
                     /gene="acm"
                     /locus_tag="L1U99_002283"
     CDS             165..2330
                     /gene="acm"
                     /locus_tag="L1U99_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HBN1212810.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2602..3087)
                     /locus_tag="L1U99_002284"
     CDS             complement(2602..3087)
                     /locus_tag="L1U99_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBN1212811.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    3177..3522
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3567..4208
                     /locus_tag="L1U99_002285"
     CDS             3567..4208
                     /locus_tag="L1U99_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBN1212812.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            4227..4862
                     /locus_tag="L1U99_002286"
     CDS             4227..4862
                     /locus_tag="L1U99_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBN1212813.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4880..5695
                     /locus_tag="L1U99_002287"
     CDS             4880..5695
                     /locus_tag="L1U99_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1212814.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            6014..7450
                     /locus_tag="L1U99_002288"
     CDS             6014..7450
                     /locus_tag="L1U99_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1212815.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKSSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7639..10071
                     /locus_tag="L1U99_002289"
     CDS             7639..10071
                     /locus_tag="L1U99_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBN1212816.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQLSFVPI
                     DSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQDYELPT
                     VDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEVQPAVG
                     VKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIEAQPNH
                     PDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRAKPHEV
                     KLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAATGVRNI
                     SGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGI
                     HMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGDMLFLP
                     MGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQPQDELF
                     EEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKVFIEQE
                     ETSETLPDDNDM"
     gene            10301..11368
                     /gene="rlmN"
                     /locus_tag="L1U99_002290"
     CDS             10301..11368
                     /gene="rlmN"
                     /locus_tag="L1U99_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBN1212817.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(11561..12664)
                     /locus_tag="L1U99_002291"
     CDS             complement(11561..12664)
                     /locus_tag="L1U99_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBN1212818.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            13216..13764
                     /gene="aac(6')"
                     /locus_tag="L1U99_002292"
     CDS             13216..13764
                     /gene="aac(6')"
                     /locus_tag="L1U99_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBN1212819.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         4758 a         2300 c         2938 g         3894 t
ORIGIN      
        1 aaaaacagtt ttttggcata tttatttttt ataaatattt gtaaaataac tatcaatttt
       61 ttagttaaaa gattggaaat gagtggggga ggaattgaag aaaggatttt tgagagatga
      121 tatagtaggt tttattttta gttaaaatag gggagataga aaaaatgaaa aagtgtagaa
      181 atattatttt atcaatgtta tttattatta ctaatataac atcactgatt cctgttcatg
      241 tctatgcgga tgcaggcaga gatatcagca gtaatgtcac ttcgttgacc gtggacccaa
      301 cgaatattac agatggagga aacataaaag taaaattctc gtttgacgaa aaaaaacaaa
      361 atatccaacc aggtgattat ctttggatca attggccaag tgaaggaaat attcgcggtg
      421 aaggattcca aaaagaaatc ccattaatga ttgaaaataa aaatgttgga actttaacgg
      481 tcagaaaaga ttctgcgcag gttgtgttta atgaaaatat taaaaaccta gactcagtag
      541 aaggttgggg gcaatttgag atacaggcca gaaacgtaac cgataccggt gaagaaaata
      601 cgggaccatt caccgtgacg agcggtgata aaacagctac tgtaaatgtg acaaagccag
      661 cttctggttc ttcttctagc gttttttatt ataaaacagg agacatgcta cctgaagata
      721 ctaagcacat tcgatggttt ttgaatatta acaataacgg cacttatgtt gaacaaccag
      781 ttaaaatcag tgatgaaatc caaagtggac aaagattaga tccaagtacg tttgaaatta
      841 atcaaataca cttaggtgaa cagaaggttt atagaggaga agagggaatc caacaatttt
      901 tacaagattt ccccagcgct acatttaatt tttcagtaac tgataattac attgaaataa
      961 ctataccaaa aaactttgtc aatcttagga aaataatggt gagttataag acgatcatag
     1021 aaaacccaga acaaataaat tttgagaatc attcggaagc ttggtttaaa gaatttaata
     1081 aacctgctgt tgatggagaa agtttcaatc atacagttaa aaatatttca gcttctggtg
     1141 gagtcaacgg tacagttaga ggcgaattga agattttcaa atatatcaat gacacagaga
     1201 ttggtatccc aaatgtgact ttcgaattaa gacgagcaga tgaacagcct attcaaggac
     1261 agtctagtat cctgttgact tcgaatgaac agggagaagc tagtatcaaa ggcctgcaag
     1321 taggagacta tgttgtaaaa gaaaaagaag cacccaattg gattgatttt gatccactaa
     1381 gttcaaatga actcaaattc tccataaacg aaaatgatac agagggagtc agtttaccta
     1441 tttataacaa gaaaaaggtt acgaacatca cagcaactaa aatttggaac ggtggaacca
     1501 ctccaagacc gagtatttat tttaaattat tcagagcaag tacaaacaat tgggaaccag
     1561 ttcctgatgc agaaacaaaa cgattagaca atggaataac ttcagtgact tgggaagata
     1621 tccaacagta tgatgatagt ggaaacgaat atacgtttaa agtgcaagaa gtagatcaaa
     1681 acggaaatga ttatgtccct tcaggttatc aaaaaattga aaacgggcta gtcgttacaa
     1741 atgagaataa agaagtcatt tcagtctcag gacaaaaaac atgggaagac aatgagaacc
     1801 aagacggcaa acgaccgacg acgatcacag taaatctatt agccgacggt caaccgatcc
     1861 aacacaaaga agtaagtgaa aaagatgatt ggcgctatcg tttcacaaat ctgccaaaat
     1921 acagagacgg gcaagaaatc atctatactg taacggaaga caacgtgccc gaatacagta
     1981 cgacgattga cgggtataac atcaaaaaca gttatacacc ggaaaaaaca aatatatcta
     2041 taccaggtag ccatataaca ccgtggaaaa attttccaga gaagacagag agagagaaaa
     2101 ttagaaatct attctctcaa aaattgcaaa tatttgctca tacaggagaa tccagcgaac
     2161 aaagaagcaa ttatattagt aagagagctg tacctaaaca gataacaaat aaatcaaaaa
     2221 gcattcttcc taaaacaagt agtaaaaaat ctagttttgc tgtaatcatt ggtttattga
     2281 tagtaactat ctgtgctggg atattcttac aaaaatataa aaaagtttag ttagaatata
     2341 atattttttg ttaaatatga ctgaaatcaa aagaataaaa ttccgattta taatcgaaaa
     2401 aagaagcatt tttatatatg cttctttttt cgtagaatca ataaatatgg atttggctaa
     2461 ctatggaaga atactcgtat tagttttcag cgttcatact agttgttaca ttgtttgatt
     2521 ggccaaaaga atttctgata tattttgtgc taaataaaga aaaagacgct tgaattggga
     2581 aataagaaaa ctactctatc attacaaatt ttcataaact ggcagatgtt ctaagtaaac
     2641 aagtatcttt tcaaagtcgg aaaaatccat aatcaacgta gtggtattga tatttggatg
     2701 aaagcctacg gtatcttgac gatcaatagc agcatcgatc acgacttgga tttttttctc
     2761 tttgtcgtgc atcaatgcta atggagtcac tgtacctgct ggaacgccta ggaggtcagg
     2821 aagctgttct tcagaaacaa aagataagcg cttttctttt aattgttcag ctagttgttt
     2881 taaatcggcg tgcttttcat caggcaagat gacaagatag atttgttttc cttttcttga
     2941 tttcaataat agatttttta cttgcggacc aggtagggaa aaagggacat ttttgactga
     3001 cgtaatcgca ggatgatcga ctttttgaaa agagataccc agttttttta gtagttcata
     3061 agcttcttgt tcggttgcac gactcatcgc gcatcaccct ccttttttta ttagtgtatc
     3121 ataaaaaaga gttgacaaat gaaaaataat catgtaaatt acacgtaaag ttaaaacaaa
     3181 tgacatcgaa aagaagagta gccgttaggt gtttttagag agtctctggt tggtggaaag
     3241 aggcagcagt taaccgtgaa acacatcttg gagtcgattt tctgaagcgt atagtaggaa
     3301 aatccgggga gcccgttaca gctgcggtcg ttgctagatg accagataag gctggctttt
     3361 ccgtgaggag tcggtaaaaa aaggtggaac cacgtgatta acgtcctttg atcttcggat
     3421 caaaggactt tttgttttca tctgaacggc aacgactgtg tgaggttttt tctgcaagga
     3481 aaaaataaac agaggtggaa ccacgtataa tacgtcctct tggcatttgc caagaggatt
     3541 tttttatttt aaaggaggaa aagaagatgg agtatttgat tgaagttatg ccgcaattat
     3601 tagtaggagc actcacaaca ttgaaattat ttttatttac cttgattggc tcattaccat
     3661 tagggattgt tttagcatta ggattgtctt tgcattttaa gccgctacgc tacttgcttc
     3721 aaacatatgt atgggttatg cggggaacac cgctgttgtt gcaactgatt tttatttttt
     3781 atgggttgcc gacgattggg atcgtttttg atcgtttcga agcagcactc attgccttta
     3841 tcttaaacta tgcagcttat tttgcagaga tctttcgtgg agggatacaa tcgattcctc
     3901 aaggtcaata tgaagcagcg caagttttgc aattaagtcc ctttcaaacg gtgacgaaaa
     3961 tcgtcatccc acaagtgaca aagattgttt taccttctgt agggaatgaa gttatcaact
     4021 tggtcaaaga ttcttccttg atctatatat taggtttagg tgacgtaatg cgtgctggga
     4081 aaatcgcgat ggaacgcgac gcgactttac tgcctttgct aggcgtggca atcatctatc
     4141 ttacattgac tggtattcta acaatcgtaa tgaaacaagt tgaaggaaaa ttaaattatt
     4201 accgctaact gataggagga agaaatatga ttgaattgaa gaaagtgaac aaagcatttg
     4261 gtgaaaaaaa aataatcaaa gatttgaatc taatcattcc agatgggaaa acattagcta
     4321 tcgtaggtcc ttccggtggc ggtaaaacca cgcttttacg tatcttggct ggcttagaaa
     4381 gttctgacag cggagaattt tatttagacg gtgtaccgtt caacccattc gagcttaaaa
     4441 tgaaagaaca agttgtagga gtcgtattcc aagacttcca gctatttcca catctgaata
     4501 tttttgaaaa cattacctta gcaccaaaaa tggtattgaa acagacaaaa gaagaataca
     4561 ccaaaaaagc agaagaatta gcggcttcat tagggattag tgatttattg aatatctatc
     4621 cttatcagct ttctggcgga caaaaacagc gggtagcgat tgccagagca ttggctatga
     4681 atccacgggt attggcttat gatgaaccaa caagtgcttt agatcctgaa ttacgccagc
     4741 aagtcgagcg tttgatccta tcattgaaag aagatggggt aacccaaatt attgtcaccc
     4801 atgatttagt atttgcagaa aatgtcggtg atcaattact aaaagtttcc ccaattcatt
     4861 aagaaaggag aagatagaga tgaaaaaaac cagttttcta ttcgctttga tcgcaggtct
     4921 tcttcttttt gcaggctgtt cgaacaaaaa aacttcagca gataattggg cgactatcaa
     4981 cgaagagaaa aaaatcgtta taggtttaga cgatacattt gttcctatgg gatttagaga
     5041 taaagacggg aagctcacag gatttgatat tgatttagcc aaagcagtct ttgaacaata
     5101 tgggattacg gtagactttc agcccattga ctggtcaatg aaggaatttg aactgaacaa
     5161 tggaacgatc gatttgatat ggaacggcta ttccaaaacg ccggcaagag aaaagaaagt
     5221 gcaatttaca aaaccttata tggaaaacga tcaagtgctg atcacaccta aagaatcagg
     5281 aatcacaaac tttggacaaa tgaataataa gagattaggt gcgcaaaatg ggtcatctgg
     5341 ttatgatgta tttacgaaac aaccagaagt attaaaagag atagtcaaaa accaagatgc
     5401 tgttttgtat gatagtttta atgaagcatt gatcgatctg aaaagcagac gggtcgatgg
     5461 tctgctgatg gataaagtat acgcagacta ttatttgaaa caaagaaacg aactagaaga
     5521 cttcaacata acaaaaggtt cttatgagag tgaggatttt gcagttggtg cacgcaagtc
     5581 agatagtaca ttagtgaaaa aaatcaatga agccctagat caactagaga aaacaggtga
     5641 attccaaaaa atatccgata aatggtttgg cgaagatgtt acgccgagaa attaacaaat
     5701 aggggactgt gacaaaagac gtgtcacagt ccctttttcc gaataaacag tgttctcctg
     5761 ccaactcctt gtgactcgga gctgaatggc aggctcacaa cctcttggta aacggtgttc
     5821 aaaagccagt ttttcggtat taagccaaat ttatgcaaaa atgtagaaag ccattttcac
     5881 aaaatttttc ttactactcg aaactaagcg actttttcac aacctccttt acataatttt
     5941 attttgttgt ggaaggggtt tcgtgttatt ctaaaagagg aacgattgaa ggttatagga
     6001 aaggaagaga tgaatggaac acaaagaact tacctcattt ccaaaagatt ttctgtgggg
     6061 ctctgcttct gcagcgtatc aagtagaagg agcttggcaa gaagatggga aaggagaatc
     6121 agtctgggat cgatttgtac ggatacctgg aaagacattt aaaggaacga acggtgattt
     6181 ggcagtagac cactatcatc gttataaaga agatattgct ttaatgaaag aacaaggtct
     6241 gaaagcttac cgcttctctg tagcttggac acggattttt cctaatggac gaggagaagt
     6301 caatcaagct gggctcgctt tttatgagag attgatcgac gaattgattg aaaacgatat
     6361 tgaacctatg ttgactttat atcattggga tcttccacaa gcattgcaag atgaatataa
     6421 tggttgggaa tcacgtcaga tcattgaaga tttcactcat tatgcagaaa cattatttga
     6481 ggcattccgc gggaaagtcc attactggat tagtttgaat gaacaaaata tcttcacttc
     6541 attaggttat ttgttagcag cacatccgcc aggtgtgaca gacccgaaac gaatgtatga
     6601 agttaaccat attgctaatt tagcaaatgc atctgtcatc aataaatttc acgagttaga
     6661 aatgcctgga aaaatcggac caagctttgc gtatacgcca aattatccaa ttgacagtaa
     6721 tcctgaaaat gttctggctg ctgaaaatgc agaagacctg atggccaatt attggatgga
     6781 tgtctatatg tggggaaaat atccgattgc tgccatgagg ttcttagaag aaaaaggatg
     6841 ggcaccaacg attgaagctg gcgatgcaga attgctagaa tctgctaaac cagattttct
     6901 tgggatcaat tactatcaaa cggcgacgaa tgcattcaat ccattaaacg gagttggtgc
     6961 tggaaaaatg aatacgacag gaaaaaaaag ttcatcagaa gaaactggag ttcctggaat
     7021 gtataaaaaa gttgagaatc catttgtcga acgaacaaat tgggactggg agattgaccc
     7081 agaaggatta aggatcggac tgcgtcgtat cacaagccgt taccgcatgc cggtactgat
     7141 tacggaaaat ggcttaggag agtatgacaa gttgacagaa gataaacaaa tccatgacga
     7201 ctatcgaatc aattacttac aaagccacgt caaagccatc aaagaagcaa tttcggatgg
     7261 agcagaagtc ctaggctatt gcacctggtc ttatacagat ttgcttagct ggctgaacgg
     7321 ttatcaaaag cgatatggat ttgtatatgt tgatcaagac gaaacacaag aaggatcttt
     7381 ggaacgatat aagaaagaca gttattactg gtaccaaaaa ctgattgaag aaaatggaga
     7441 gaacctttag ttcacatact taaaacaaga aggtacggct ggatatggcc gtgccttttc
     7501 ttgataaaat catttagaaa ttaagaaaaa ctgtaaaata agctgaaaaa tgaaagaaag
     7561 cgtcagttct ttcaaacaaa actttagttc ccttactttt ttttgtataa tgaaacttga
     7621 tgaaatgagg gataataaat ggcacaaaag aaacggccta ctaaaaaaag gaaaaagacg
     7681 aaaaaaacga aaaagcaaaa acagcagcag gaacaaatgc tgacgattgg tgttgggttt
     7741 gccttgattt tatttgctgt cttcggcttt ttaaaattag gttttttagg aatattgatt
     7801 gcaaacggct ttcggatcat tgcaggaaat acttaccaaa tcctctgtct tttattagcc
     7861 gtattaggat tttggattgt cattaagaat acagagtttt caattggtaa aaaccgacgc
     7921 tggtttggcg gcatactctt ttatttcggt atcttattat tgttacatgc ccatttattt
     7981 ggcaaactcc atactgggga accaaatatc atggggacga catgggattt gttagccagt
     8041 gatataaaac aaagtcaagt agacaataac gttggtggtg ggatgattgg agcaatcctt
     8101 tatcatttta cttacttctt gattgcacag cctggaagtt atttagcagc agtgctatta
     8161 ctggcaggag gagcattcct gttcagtaat ctggaaggct atcagctgtt aaatggtatc
     8221 caatcaattg gagaacgagt acaggaatta ttggaaggtg atcctgccaa gcaagctcga
     8281 aagcaagcgg caaaggaaga gagaatgaaa cagcgcgcag aagcgaaaga agcaaggcgc
     8341 ttagctgcaa aagaagctgc agaatatgag aagaaaaaag cggtgagcca gcaaagggaa
     8401 aatactgctg atgaatggca ggaaccagaa aatacagagc cggagcagct aagttttgtt
     8461 ccaatcgaca gttttcaaga aaatatccat cctgcgaatc tagagaaacc agtaccagat
     8521 acaccaaaac agaccaatac agcagaaggt ttttcagatg agttgccaga ggatgacggt
     8581 acctcattag aatttgagat tgaagcagaa caggaaaatc aagactatga attaccgaca
     8641 gttgatttgc ttgattctat accaactgtg gatcaaagtg atgagtataa aaaaattgaa
     8701 aaaaatatcg gcgtattaga acaaactttc caaagtttcg gtgtcgatgc caaggtcgtc
     8761 aaagccagct taggaccatc cgtcacaaaa ttcgaagtcc agccggctgt aggggtaaaa
     8821 gtaagtaaaa ttgtgaactt aacagatgat atcgcgcttg ctttagcggc gaaagatgtc
     8881 cggatggaag caccgattcc aggtaaatca ctgattggta ttgaagtacc aaatggaaag
     8941 atcagtatgg tttcctttag agaaatcatc gaagcacaac caaaccaccc agataaatta
     9001 ctagaagtac ctttaggacg tgatgtttct ggacgggtac aaacggctga tctttcgaag
     9061 atgcctcact tactcgtggc tggttcgact ggtagtggga agtcagtagc aattaatggg
     9121 attatcacaa gtatattaat gcgtgctaag ccccatgaag taaaactgat gatgatcgat
     9181 ccgaaaatgg ttgaattgaa tatgtacaac ggcatacctc atctgttgac gccggtcgtg
     9241 acgaacccta gaaaagcagc gcaagcctta caaaaagtag tacaagaaat ggaagaacga
     9301 tatgaaaaat tcgcggcaac cggagtaaga aatatttctg gttacaatga atttgttcaa
     9361 cagaaaaact tggaaaacgg aacgaaacat ccaaccttac cattcatcgt agtgatcgta
     9421 gatgaattag ctgatttgat gatggtagcc agcaatgaag ttgaagatgc gattattcgt
     9481 ttagcgcaaa tggctcgggc agcggggatt catatgatcc tagctactca acgtccaagt
     9541 gtggatgtta tcacaggaat catcaaagca aatgtacctt ccagaatggc atttgcggta
     9601 tcaagcggta cagattctcg gacgatcatt gattctaatg gggcagaaaa gctcttaggg
     9661 cgaggagata tgctattctt gccaatgggt gagaataaac cgatccgtgt gcaaggagca
     9721 ttcatttctg accacgaagt agaacgggtc gttcaatttg ttacagatca gcaagaagct
     9781 cattatgaag agaaaatgat gccgacagat gaagttgaaa cgacaggtgc tccagaacag
     9841 ccacaagatg agctgtttga agaagcaaaa gcacttgtcg ttgaaatgca aacggcaagt
     9901 atttcccttc tccaaagaag atttcggatc ggttacaacc gagcagcacg tttagtagat
     9961 gaactggaag ctcatggagt tgttggcccg tcagaaggaa gcaagcctcg gaaagtattc
    10021 attgagcagg aagaaacatc agaaacgttg ccggacgata atgacatgta aaacttgtgt
    10081 gatgaagggt tgaaaaacga ataaccaata aaaagacaag gcatgatgat accaaaagaa
    10141 aaaatggttt ttttccatct tttctaatac ggtatgatgt cttgtctttt tagtttttgt
    10201 gagattaaag ttctattcga tttatttgtg aagtattgca ttaaggaaat gaatcatgta
    10261 tagtatgtag cgaaactttg agaaaaagag ggaaaatact ttggaaaaac agtccattta
    10321 tggcttgacg aatgaagaat taatcaattg gtttatagaa aacggcgaga aaaaattccg
    10381 agctgcccaa gtttgggaat ggttgtatca aaaacgtgta agtaatttca cagaaatgac
    10441 gaatctatcg aaacaattga tcgaaaaatt atcggagcat tttatcatca atcctctaaa
    10501 acagatggtc gtccaagaag cttcggatgg tacagtaaaa tatttgtttg aactccctga
    10561 taaaaacatg attgagactg tactgatgag acaagaatat ggcttgtcag tttgtgtgac
    10621 gacacaagta ggatgtaata tcggctgtac gttttgtgca agcgggctgc tcaaaaagaa
    10681 ccgtgatctg actgctggag aaattgttgc acagatcatg atggtccaac attattttga
    10741 tgagcgcaat cttggcgaac gcgtttcaca tgtcgttgta atggggatcg gtgagccatt
    10801 tgataattac gacaatgtaa tggacttttt gcatatcatc aatgatgcca aaggattggc
    10861 aattggtgct cggcacatta cagtttccac tagtggatta gcacacaaaa tcaaggaatt
    10921 cgctaataac ggcttgcaag tcaatctggc tatttccttg cacgcgccga ataatgaggt
    10981 gcgaacatcg atcatgcgga tcaaccgaag tttcccaatt gagaaattga tggaagctgt
    11041 ggatgagtat ttagagaaaa caaaccgtcg aatcacgttt gaatatatca tgttgaatca
    11101 agtaaatgat agaccagagc atgcgcaaca attagcagat ctattaaaag ataagaaaaa
    11161 attagcatat gtcaacttga ttccatataa tccagtcagt gaacatgatc aatattctcg
    11221 cagtccaaaa gctgatgtat tgagatttta tgatgtattg aagaaaaacg gcgtaaactg
    11281 tgtgatacgt aaagaacatg gtacagatat tgatgcagct tgcggacaat tgcgaagcaa
    11341 gcaaatgaaa aaaacagttg ccaaataatc gtatcctact cgttttttca attaccataa
    11401 aaggagcagt tttcttaatt aaggaactgt tcaacttaaa taagagaaaa gattctatag
    11461 cgaaagctat aaagcttttt ttgacaagaa aaaccctcat caagcaaaga aatgtcctca
    11521 atttgatgac agcctgcttg atgggggttt tagcaattat ttaactgatt ttcttatatc
    11581 cttgctggct ttcttgtgta gcatgataag tttctacgtc aagaatggcc tgtttaaatt
    11641 tttctcgggt gatttcataa ggcacatgtt taatatcatt tgttgccatg gctttatcta
    11701 agattgcttc taaatcggtc gtgacattga gattcatgtc ggttaacgat actggaagtt
    11761 ggttcttttt cataaacaca tagattttat caaacaaatc gaactgctga tccatcatca
    11821 ataaggtcag tacaccataa ctgacagatg ctccgtgaag gtatccctcc attttttcta
    11881 gaacagtcgt accgtaatag aatgagtgtg ccatagcaga attatagtta ttgttaacta
    11941 aaacagaaac caatccggta gtaacaatga tatccgaaac gacttgttca attgcatatg
    12001 agggacgatc gtcggcacta tctttcaatg cttgcgtacc ataagtcaag agacgatcaa
    12061 tgcacatttt tccgatttgg attcctaatc tatccgtgta gcctagatca tcgccacgag
    12121 cagaaaaagt agattcgact tctttggata aagcatcgcc aatacctgcc cataagtatt
    12181 tatcaggtgc ttcggcaata attgctgtat caatgaaggt gtgtacaggt ggttttgaag
    12241 gaaagaagag tccgtccatt acgccttctt cgttatagat gacacatacc gcagtgacgg
    12301 gcgaacagtt cgaaccaata gtgggaaagg tgaagactgg tttagctagt ttttcaccaa
    12361 tgacttttac agtatcgcaa gcacggccac caccgactgc aaacaggacg tctgcttttt
    12421 ggacactttc atgctggatc aactgttcaa tatttccata agttgaatta cccccgtacc
    12481 agagactggc gacaacctct atttcctgtg tcaaagctac ttttattttg ttttctgcct
    12541 ttgaaagtgc agtcttccct ccaatcagca ctacttttgt cccatattct ttgacgattc
    12601 catttgcttt ttcatacgca tctgttccaa tggtataatt tggtaagaaa acactttgac
    12661 tcatattcat ttccttcttt cttcgttgaa acgggttaaa attttaaaga gtgatcgatc
    12721 tgactgcggc tgtagatgga gtagaggtga acctaagaca ggataagtga tgaataaggt
    12781 ggcatgaaca ccttgaaatc atcaataagt atcctaaaaa cgaacaagta caaaaacatt
    12841 gaaaacgaca ataatgaatt tttgttcctc ttagtatttc taccgattcc ctttgctttt
    12901 ttgtaattat ctaaaaattc taaaaattaa gattattata tgaaaacagg ttttatttgt
    12961 caattcataa ttggtttttt ttaaagcaaa agataatcta tatcatgatg aacaaacaga
    13021 gttttttcct ccaattgatg gctttcctga tctttcctat tttgaataaa gtgtttctgt
    13081 ataatttttt attttataag taagataaat aatgaaagaa tagagatact gattggtagc
    13141 taaagatttt tgagcgagaa catttcgttt tttcaaaagg actgttagaa taagcaagaa
    13201 caagggggaa gacgtatgat aatcagtgaa tttgaccgta ataatccagt attgaaagat
    13261 cagctttctg atttactgag actgacttgg ccggaagaat atggagacag ctcggcagaa
    13321 gaagtagaag aaatgatgaa tccagaacga atcgcggtag cagcggtaga ccaagatgag
    13381 ttagtaggat ttattggtgc aatccctcaa tacggtatca caggttggga attgcatcca
    13441 ttagttgtag aaagctcccg acgaaagaac caaataggta ctcgattagt caattactta
    13501 gaaaaagaag tagcttccag aggaggaatc acgatttatt taggtacgga tgatttagac
    13561 catggaacaa cgttaagtca aacggacctg tatgagcata catttgataa agtggcttcc
    13621 atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa aattaggtta taaaatcgta
    13681 ggtgtcttac caaatgcaaa tggctgggac aaaccggata tttggatggc aaaaacgatt
    13741 attcctcgac caaattctca ataataaaaa gaggttgtga cagaagtaat cagcttcaag
    13801 aaataagaag gaatttacga aaattacttc ttgaattttt gtgaaattcc aacttatttc
    13861 cgaagaagct acttttggaa caccgtgtac
//
LOCUS       DAFLVO010000073        13704 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.073, whole genome shotgun sequence.
ACCESSION   DAFLVO010000073 DAFLVO010000000
VERSION     DAFLVO010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13704
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.073"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            106..348
                     /gene="yaaA"
                     /locus_tag="L1U99_002293"
     CDS             106..348
                     /gene="yaaA"
                     /locus_tag="L1U99_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBN1212820.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            335..1459
                     /gene="recF"
                     /locus_tag="L1U99_002294"
     CDS             335..1459
                     /gene="recF"
                     /locus_tag="L1U99_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBN1212821.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            1456..3402
                     /gene="gyrB"
                     /locus_tag="L1U99_002295"
     CDS             1456..3402
                     /gene="gyrB"
                     /locus_tag="L1U99_002295"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBN1212822.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            3422..5893
                     /gene="gyrA"
                     /locus_tag="L1U99_002296"
     CDS             3422..5893
                     /gene="gyrA"
                     /locus_tag="L1U99_002296"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBN1212823.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            6129..6428
                     /locus_tag="L1U99_002297"
     CDS             6129..6428
                     /locus_tag="L1U99_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBN1212824.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            6478..6990
                     /gene="ssb"
                     /locus_tag="L1U99_002298"
     CDS             6478..6990
                     /gene="ssb"
                     /locus_tag="L1U99_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBN1212825.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            7016..7252
                     /locus_tag="L1U99_002299"
     CDS             7016..7252
                     /locus_tag="L1U99_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBN1212826.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            7395..9368
                     /locus_tag="L1U99_002300"
     CDS             7395..9368
                     /locus_tag="L1U99_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBN1212827.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            9374..9826
                     /gene="rplI"
                     /locus_tag="L1U99_002301"
     CDS             9374..9826
                     /gene="rplI"
                     /locus_tag="L1U99_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBN1212828.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            10100..11467
                     /gene="dnaB"
                     /locus_tag="L1U99_002302"
     CDS             10100..11467
                     /gene="dnaB"
                     /locus_tag="L1U99_002302"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBN1212829.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            12247..13539
                     /locus_tag="L1U99_002303"
     CDS             12247..13539
                     /locus_tag="L1U99_002303"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBN1212830.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT         4574 a         2470 c         3016 g         3644 t
ORIGIN      
        1 agattaaatc gtcttatatg gaaaaatata tggataaatt tgttttattg cgaaaaaaaa
       61 ggtataatag agtatacttt taataatgaa aatgagggat gggcattgaa acaacaagtc
      121 attctaaata cggaattcat gacgttgggc caaatgttga aagaagtcac agttatcggt
      181 agtggcggac aagcaaaatg gtatttggca gaaaacactg tgttagtcga tggcgaacca
      241 gaaaatcgtc gtggacgcaa actttatccc ggcatgatgg ttgaagttcc agaagtagga
      301 acttttttta tggtaaaaaa aggaaacgac gataatgagg ctgaataagc tgtatttaaa
      361 aaattatcga aattacgaag agctgaacat cgaattttcc aagaacctcg tcatcttttt
      421 aggagaaaat gcgcaaggaa aaacgaatct tttggaaagt atctacgtat tagctatgac
      481 gcgaagtcat cggacaagta gtgagcagga attgattggc tggactgacg atcaggcgat
      541 gattcaagga gagatcacaa aaggttcatc cactcttcca ttagaaatct tattatctaa
      601 aaaaggccga aaaaccaaga tcaaccatat cgaacagaaa aagttaagta cttacgtggg
      661 acaaatgaat gtcattttat ttgcaccaga agatctttct ttagtaaaag gcagcccgca
      721 gatcaggcgg aagtttttag atatggaatt aggccagatc aatccaatct atctttatga
      781 tcttgtccaa taccaagcaa ttttgaaaca aagaaaccag tacttgaagc aattgaatga
      841 aaaaaaacaa actgatttgc tttatttgga tattttgtcc gaacaactag cagcgtttgg
      901 cagcaaagta ttgaaagcaa gagcacagtt cgtcaagcga ttggagtttt gggctaattc
      961 tttgcatcag caaatcaccc atcaaaaaga gcagctggaa atcgagtatc tcaccgcagt
     1021 cgattcttta gaaacacata cgcaagagca aatccaagaa caatttctcg cacttttgaa
     1081 ccaaaataaa aagaaagacc tttttcgggg aacaacgaca gttggtcctc atcgtgacga
     1141 tctttccttt tttattaatc agaaaaatgt gcagacttat ggatcgcaag gacagcaaag
     1201 aacaactgca ctaagtgtca aattagcaga aatcgatttg attaaagaag agacagggga
     1261 atatccaatc cttttgttag atgatgtgat gagcgagctg gatgataatc gtcaactcca
     1321 tctgctagaa acaatcgaag gaaaagttca aacgttctta acaacaacga cacttgacca
     1381 tgtaaaaaat aaaatgactg ttgaacctga gattttttat gttcaacaag ggaaactaaa
     1441 aggagaagaa actgaatgac agaagaaaga agtttagtag aacgcgctaa agagtatgat
     1501 gccagtcaga ttcaagtact tgaaggactt gaagccgttc gtaaacgacc tggcatgtat
     1561 atcggttcga ctagttctga gggtctgcat caccttgttt gggaaattgt cgataattcg
     1621 atcgatgaag tattagcagg ttttgcaacg aaaatccatg tgattattga aaaagacaac
     1681 agtatcaccg ttattgacga cggtcggggg atacctgtag atatccaggc aaaaactgga
     1741 cgtcctgcag ttgaaacggt ctttactgtt ttacatgctg gaggaaaatt cggcggtggt
     1801 gggtacaaag tttctggtgg acttcacgga gtaggatctt ctgttgtaaa cgcgctttct
     1861 acacagcttg atgtcaaagt atacaaagaa ggaaatgtgt actatcaaga atatcgtcgt
     1921 ggagctgtag tggacgactt aaagattatc gaacaaacgg atcgccatgg aacaacggtt
     1981 cactttacgc cagaccctga aatttttaca gagacaactg agtttgattt ttcaaaattg
     2041 gctacccgga tccgtgaact tgctttcttg aaccgcggga tgcgtatatc gattgaagac
     2101 aaacgagaag aagaaccagt catcaatgaa taccattatg acggcgggat caaaagttat
     2161 gtcgaatact tgaatgcaaa caaaaccgtg atttttccag aacctgtata tttggaaggt
     2221 gaacagcaag atatcgcagt tgaagtctct atgcaatata cagacggcta ccattccaat
     2281 atcatgagtt ttgccaacaa tatccatacg tatgaaggtg gaacacatga atcaggattc
     2341 aagactgctt taactcgtgt gataaatgat tatgcccgaa aacaaaagct gatgaaagaa
     2401 aatgacgaca acttgaccgg tgaagacgtg cgagaaggat tgacagctgt tatttctatc
     2461 aagcatcctg accctcaatt cgaaggacaa acaaaaacaa aattgggcaa ttccgaagta
     2521 cggacagtca ctgatcggtt atttagcgaa catttcatga aattcttgct ggaaaaccca
     2581 agtgtgggcc ggcaaattgt tgaaaaagga ttactagctt ccagagctcg tctagcagcg
     2641 aaacgtgcgc gtgaagtaac gagacgtaaa ggtgctttag agattagtaa tctgccagga
     2701 aaattagcgg actgctctag caacgatcct gaaaaatgcg aattgttcat cgtcgaagga
     2761 gattcggccg gcggatcagc taagcaaggt cgtaatcgag agtttcaagc catcttgcct
     2821 attcgtggga aaatcttgaa tgttgaaaaa gcaagcatgg acaagatctt ggcaaatgaa
     2881 gagatccggt ctttatttac tgctatgggt acagggtttg gagaagattt tgatgtatcg
     2941 aaagctcgct accacaaatt agttatcatg actgatgccg atgtcgacgg cgcgcatatc
     3001 cgtacattgc tgctgactct tttttatcgt tacatgcgtc ctattgttga agctggatac
     3061 gtctatattg ctcagccacc tttatacggg gtaaaacaag ggaagaatat tacgtatgta
     3121 caaccaggaa aaaatgcaga agaagagttg aaacaagtcg ttgcttcact tcctgcctca
     3181 ccaaaaccaa gcgttcagcg ttataaagga cttggagaaa tggatgatca tcaactatgg
     3241 gaaacaacta tggacccaag caatcggatg atggcccgcg tcagtgtgga cgatgctatt
     3301 gcagcagatc agatatttga aatgttgatg ggggatcgag tagaaccccg tcgtgcattc
     3361 atcgaggaaa atgcacacta tgtgaagaac ttagatattt aatcatgaag gaggaaaaag
     3421 aatgagtgaa gaaatcagag aaaacatcca tgatgtcaat ctaaccagcg aaatgaaaga
     3481 ctccttcatc gattatgcga tgagtgttat tgtcgcacgt gcacttcctg atgtcagaga
     3541 tggtctgaaa cccgttcatc gccgtatttt atacggcatg aacgaattag gtgtaacacc
     3601 ggataaagcc cataaaaaat ctgccagaat cgtcggagat gtcatgggta aataccatcc
     3661 tcatggagac attgcgatct atgagtcaat ggtacggatg gcacagccat tcagctaccg
     3721 ttatatgcta gtggatggtc atggaaactt tggttctgtt gacggtgacg gtgccgccgc
     3781 tatgcgttat accgaagcac ggatgagcaa aatcgctaca gaaatgctgc gtgatatcaa
     3841 taagaacact gttgatttcc aaagcaacta tgatgataca gaaaaagaac cagttgtact
     3901 acctgctcgc ttcccgaatc ttttagtgaa cggaacaacg gggatcgccg taggtatggc
     3961 cacgaatatc ccacctcata acttgtctga ggtagtagcg gctatcgatt tgctgatgga
     4021 taatcctgat gtgacgacca atgaattgat ggaagtatta cctggaccag attttccaac
     4081 aggtggtttg gttatgggga aatcaggaat ccgaagagcg tatgaaacag gtaagggttc
     4141 tattaccgta cgtgcaaaag ttgagattac tgagatgcca aatggtaaag aacggatcat
     4201 cgtgacagaa ttgccttata tggtcaataa agcaaaattg atcgaacgga tttctgaact
     4261 gcacagagac aagcgtatcg aagggatcac agatttgcgg gacgaatctt cccgtgaagg
     4321 tatgcggatc gtcattgaca tccgtcgtga cgccagcgca tccgttatct tgaataactt
     4381 atataaattg acatccttgc aaaattcatt tggattcaat atgttggcga tcgaaaaagg
     4441 tgtgccgaaa gttttgagct tgaaacaaat ccttgaaaac tatatcgaac atcaacgcga
     4501 agtcatcaca cgacggacgg tctttgaaaa agaaaaagca gaagcaagag cacacatctt
     4561 agaaggtttg cgtattgctt tggatcatat cgatgaaatc attgcgatta tccgcgggtc
     4621 taaatcagat gacgaggcaa aagcaacaat gatcgaacgg ttcgatttat ccgatcgcca
     4681 gtctcaagct attttagata tgcgtttacg ccgattgacc ggtttggaac gggaaaaaat
     4741 cgaaaatgaa taccaagaac tcttaaaact gattgaagat ttaactgaca ttctggcaag
     4801 accagaacgt gttacagaaa tcatcaagaa tgaattagca gacttgaatc aacgatttgg
     4861 tgataaacga cgcacagaat tactagtcgg tgaggtctta agtctggaag atgaagattt
     4921 aatcgaagaa gaagaaatcg ttattacatt gacaaacaat ggttacatca aacgtttggc
     4981 aaataatgaa ttcagagctc aacgaagggg tggacgtggt gtccaaggaa tgggtatcca
     5041 caatgacgac ttcgtcaaaa atctggtttc ttgttctacc catgatacat tgttattctt
     5101 tacgaataac ggaaaagtgt atcgggcaaa aggatacgaa attccagaat acgggcgtac
     5161 agccaaagga atcccaatca tcaatttact aggtatcgat tcgagtgaaa gcatccaggc
     5221 aatcattgcg gtgacgggag aagcagaaga aggccactat ctcttcttta cgacgcgtca
     5281 aggtacagta aaacgtactt ctgtcactgc ttttgctaac atccgaagta atggtctgat
     5341 cgcaattggt ttgaaagaag acgatgagct cgtcaatgtg ctactgacag atggtcaatc
     5401 taatatcatt attggaacac ataacggcta ctctgtcact ttcaaagaag aagcagtccg
     5461 cgatatggga cgtacagctt ccggggtcag agggatacgc ctgcgtgagg aagattatgt
     5521 cgttggggca gccttaatga aggaaaatca agaagtatta gtgatcacag aaaaaggtta
     5581 cggaaaacgg acaaaagtat cggaatatcc agtgaaaggc cgcggaggta aagggatcaa
     5641 aacggcgaac atcactgaaa aaaatggtcc actagctgga ttgaccactg tttctggaga
     5701 tgaagacatc atgctgatta cagataaagg tgtcattatc cgtttcaacg tatcgactgt
     5761 ttctcaaact ggacgttcaa cattaggcgt acgtttgatg aagatggaag ctgatacgaa
     5821 agttgtcacg atggcagcag tcgaaccaga agctgcagaa caaacagttg aagaacaagg
     5881 atcagaagaa taaccatcaa gactaagtgt gtaagctagc aagaataacc gattaaaaaa
     5941 tctggttatt cctgctggct tttttgatta gttgaatttc tcttaaaata ttcgaaactg
     6001 ttcattctgt attgcttttg accaaaatag agtgtataat tagagcttgt gagtagtcta
     6061 attaattaga taactctcct tgctcttagg aacctaagag ccgaaagtcc acagggaggt
     6121 gaatatcaat ggaaaacacg aaatatgaaa tcatgtacat tattcgtcca aacattgatg
     6181 aagaagcaaa aactgcttta atcgaacgtt tcgatgcaat cttgaaagat aacggagcag
     6241 aagttatcga atcaaaagat tgggaaaaac gccgtttcgc ttatgaaatg aacggttacc
     6301 gtgaaggtat ctatcacatc gttaaagtat cttctccatc atcagcaaat gctgtcaatg
     6361 aatttgaccg tcttgctaaa atcaacgacg atatcattcg tcacatgatt gttaaagaag
     6421 aagcttaatt gttgtttcat gtgaaacaat agaaaacgat gagaggagat gactattttg
     6481 attaataatg ttgtattagt tggacgtctg acgaaagatc cagatttgcg ttacacagca
     6541 agtggtacgg cagtcgcaac atttactttg gctgtgaatc gtaattttac aaaccaaagc
     6601 ggcaatcgcg aggctgattt tatcaactgt gtgatttggc gcaaatcagc agaaacttta
     6661 gcaaactatg ctcgtaaagg aacactttta ggtgttactg gacgtatcca aactcgttct
     6721 tatgataatc agcaaggaca acgtgtatac gtgacagaag tagtagctga caacttccaa
     6781 ttgctggaaa gtcgttctgc atctgaaaat cgccaacaaa gcggcggatt ccaaagttct
     6841 ggtcaatcag ctggcggatt tggcggaaac aataactcta atcaaacatc tcaatcatcc
     6901 aacggtatgc ctgatttcga ccgtgatact tctgacccat tcggctcaag ttcaacgatc
     6961 gacatttcag acgatgattt accattctaa acgaatttga taggagggaa atagaatggc
     7021 acaacaaaga agaggcggac gtaaacgtcg taaagtagac tacattgctg ctaaccatat
     7081 tgaatatatc gattataaag atatcgaatt actaaaaaga tttatttcag aacgcggtaa
     7141 aatcttgcca cgtcgtgtaa ctggtacagg cgctaaaaac caacgtaaaa ttactgttgc
     7201 aatcaaacgc gctcgtatca tgggcttgct acctttcgtt agcgaagact aataaatcct
     7261 aggaattgaa tgactgatcc ttttgatcag ctattcaatt cctttttttc tgtaaaaata
     7321 acctctattc gtttagtcgc tcgaatgacg aaagttatgg taaaatcaaa ttagtcatat
     7381 atgggaggaa aattatggaa aataaaaaca atcatttatc cccgaaacct ctcttcctta
     7441 tcctgtttat attaatcgaa gtattggtag tcttaatttt accatttcgt tttgttagcg
     7501 cttcggtcat tctattgatg aatttatggg gtgttcgcta ttggttgaaa atgaaacgtt
     7561 ggcttatttt aaataaacgt gaaaaaatcc agcaggcttc gactgtagct gaaaccaatc
     7621 tagcttatgt ctcagaagtc atgcctgtag gagtgattgc ttatcagcca tcaagccaaa
     7681 aaatcgaatg gctcaatcca ttagcattga aaatcaaaga tcaaagtgga ttaacagagg
     7741 aagaattgct agatactttt tttactgcaa aagaaaaaaa gaaaaaccaa gtctatctag
     7801 cagataaaac atttcagttt gatatggata cagtaaaggg tgttgtttat tttaatgata
     7861 ttacccaaaa ccagttgtta aaactccatc agacgaacag tcagccggtg attggtattt
     7921 tatctattga taactatgca gatgccattg ataaattaga tgacaaagag atttcttatt
     7981 tgaactcttt cgtcactaca ctagtttctg actggatgaa tgaataccat gtctttttca
     8041 aaagaatcaa cgcagaacgg tttttcttcg tagcacagat gatcgatctg aaaaagatga
     8101 tggataaaaa atttgatttg ctggatcgct ttcgagcaga agctgaaaaa cagagctcgc
     8161 ctatcaccct tagtatgggg attgcttatg gctcaagaac cctcgatgaa atcggtggag
     8221 aagctcagaa taatttagat gttgctttag tccgtggagg cgaccaagtt gtcgtgaaag
     8281 aggtaaaaga aggagcaaaa cctgtttatt atggggggaa atctgctaag aatgtcaaac
     8341 gcacgcgtgt tcgttctcga gcgatgagta ccgctttgcg tcggattttt gatgaaacag
     8401 gcgatgtgtt tatcatgggg cacaagtttc cggatatgga tgctttaggc tctgcttttg
     8461 gtgtcagttg tctggcacgc ttcaaccaga aaaaagctta catcgttatc aatgagaacg
     8521 agatcattcc agatgtagaa cggtgtcttg aagaaatcca taagcatcct gaattagaaa
     8581 tgcaactaat ctctccagaa cgtgccatag agctgaaaaa agaagaggac ctcctcgtga
     8641 tggtggatta ccataaacct tctctatcga tctctcaggg cctatatgag caatttgata
     8701 agattgtgat cattgatcac catcgtcgtg gggaagagtt tccaagtaaa cctctgctga
     8761 cttatattga atcttcagct tcttcagctt cagagctagt ttctgagctg atccaatacc
     8821 aaagcagcaa aacaaatcgc ttagatcgtt ttgaggccac attattgctt gcagggatgg
     8881 ttgtagatac aaatagtttc aatgtccgta caactgcacg aacttttgac gttgccagct
     8941 atttaaggtc ttgtggagca gacgcatcct tagtacaata tttattgagc tcggatttag
     9001 cgacatactt ggagatcagc aatttgattg ctggaagcga ctatgtgact tctgatattg
     9061 ttgtggcggc agggacagac gaaaaagagt ataatagtgt tatagcagca aaaacagcag
     9121 atacattgct ttcgatgatc aatatcaatg cagctttcgt cattacaaag cggacagacg
     9181 gcttgattgg gatcagtgcc agaagtaccg gcacgatcaa cgtccaaatc atcatggaat
     9241 ccttaggtgg cggaggacac ttcacaaacg cagctactca actggaaaat acgacagttg
     9301 aggaaacaaa acagaagcta tttgctgcaa tcaaagaaaa tatgaatcaa atatatgata
     9361 aggagtaatc caaatgaaag taattttttt acaagatgta aaaggaaaag gtaaaaaagg
     9421 ggacatcaaa gaagttccag caggttatgc acaaaattat ctaatcaaaa ataacttggc
     9481 aaaagaagca acgaaaagca gtatcagtca gttagcagga caaaagaaag cacaagaaaa
     9541 acacgaagct gaaatcttgg aagaagctaa aaagttaaaa gaattcttgg aaaaagaaga
     9601 tactgtagtc gaattgaagg cgaaagcagg ggaagacagc cgtttgtttg gttcgatccc
     9661 ttcaaaacaa attgctgaag ggttaaacaa acaatacaaa atcaaattag ataaacgaaa
     9721 aatcgaatta gaaaatccga tccgttcact aggctacaca aacgtacctg ttaagcttca
     9781 tcatgaggtg acggctacga tcaaagttca tgtcgtacaa gaataacaaa tcttgatagc
     9841 gatgttcagc tggtaagtat aaccagaagg aaaaaagaca aaccgaaatt tatctgagaa
     9901 aacagctgca gcaatgaaag caaaagctgc aaatcgattt cagattgatt tcggtttctt
     9961 ttttgggaac agcaaaatag cataaagaaa acgagtataa taaaagagaa ctattttttt
    10021 attacacttt cggtacgaat gatgactttt ctctcatttt cttgtaaaat gaagcaattg
    10081 aagacaagga gcgatacgta tgaatgaagt gtggcaggat cgaatcccac cgcaaaatat
    10141 tgaagctgaa caagcggttt taggctctgt ttttcttgac gcagaaacga tcattgatgc
    10201 catggagtac atagagccaa aagactttta tcgtcgtggc catcaaatta tttttgagac
    10261 aatgatcgag ttaaatgatc gtaatgaagc gattgacgtg gttactgtca aagaccggct
    10321 ggaacaagcc aatttgttag aagatgccgg tggtttaagt tatctctcag acttggcatt
    10381 agcagttccg acagcagcaa atatcgtcta ctatgcgaaa atcgttgaag aaaaatcatt
    10441 gctgcgtaca ttgatccaga cagcaacagg aatcgttacg aaaggattcg agcaaggaga
    10501 agaagttcaa acaattttag atgatgccga acgcagtatc ttggaggttt cggaaaaaag
    10561 aaatcgaagc ggctttttat ctattgctga agtactgaac tccacgattg aaaatatcga
    10621 tcgactagct caaaacaatg aagaaatcac aggtctacca actggctatc aaggtctgga
    10681 taaaatgaca gcaggtttcc agcccgaaga actaatcatt cttgctgcac gtccagcggt
    10741 aggtaaaaca gcgtttgcat tgaatattgc tcaaaatgta ggaacaaaaa cagatcgttc
    10801 tgttgcgata tttagtttgg aaatgggggc agaatctctt gtaaatcgga tgctttgtgc
    10861 agaaggttcg attgaggcca gccatttacg tacaggtcag ctttcggaag aagaatggtc
    10921 gaatctgatc gttgcgatgg ggagtctttc tcgagcaaat atttttatcg atgatacacc
    10981 agggatcaaa atctctgaaa tccgtgcgaa atgtcggaaa ctagcgcaag aaaaaggcaa
    11041 tctaggcttg atattgatcg attatttgca gttgattgaa ggtaacggta aagagaaccg
    11101 tcaacaagaa gtatcagata tctctcgcca actgaaaaaa ctggcgaaag agctgaaagt
    11161 acctgtcatt gctctttcac agttatctcg tggagtagaa cagcgacaag acaaacgacc
    11221 agtgctaagt gatattcgtg aatccggatc aattgaacaa gatgcggaca tcgtagcctt
    11281 cttgtatcga gatgattatt atgaaagaga aggcggagat gacgatgatg gaaacgagcc
    11341 aaaaaatgac aacgtcatcg aagtcatcat cgagaagaac cgaagcggtg cacgaggaac
    11401 agttgaacta ctgtttatca aagaatacaa taagttttcg tcgctttcgc caagagaaga
    11461 attttaaaga agaggttgtg agccttgagc aatcccgaga gctctcgtaa gaagatgcaa
    11521 ggagtaaccg caggaacgac tagagtactt aatttaaaca gatctccaaa gggattgtga
    11581 caaaagtctt gtcacagtcc ctttttccga ataaacggtg ttcaatcagc tgacccttgg
    11641 tattagctca gcaaacgtca aaatatgagg aactattttg acgtttgttt ctctaatact
    11701 caggtcaaaa cgctgatctt acgacctctt ttccttaaac ggtgttctcc tgccaactcc
    11761 tcggtcacaa gtcacaatat catcaaacat gagaagcagt tttttgaaat tgctccttgt
    11821 gactcagagt taaacggcag gctcacaacc tctttcttaa acggtgttca aaagcttgca
    11881 tctgcggtaa tacgcccaat caaacgaaaa atatgagaag ctatttttgt ttggctgttc
    11941 ttattacttg atgcaggaca gctttttcac aacctctgat tcacggtgtt ccaaaagtag
    12001 cttcttcgaa aaataagtcg aaatttcaca aaaatttgag aagcaatttt cgtacattcc
    12061 ttcttatttc ttgaagctga ccacttctgt tacaacctct tttttaataa ccattctaaa
    12121 aagataaagt tcgtttttta agcgttttta taaaataaaa ataaaaatca ttcgatttta
    12181 tttgaaatat gtatctatta ttgatacaat ggttcaggat taaataatat agaacgaggt
    12241 gttcacatgt catctgtagt agtagtaggt acgcaatggg gcgatgaagg gaaaggaaaa
    12301 atcacagact ttctcagtga aaatgctgaa gtgattgcac ggtaccaagg tggcgacaat
    12361 gcagggcaca caattaagtt taacggtgtg acttataaac tgcatttgat tccttctggg
    12421 attttttata aagacaagat cagtgtgatc ggaaacggcg ttgtagtcaa tcctaaatca
    12481 ttggttaaag aattagctta tttacatgaa aaaggtgtag aaacaagtaa tttgcgtatt
    12541 tctgaccgcg cgcacgtaat cttgccttat catatcaaat tggaccaatt acaagaagat
    12601 gctaagggcg aaaataagat tggtacaacg attaaaggaa tcggacctgc ctatatggat
    12661 aaagcagctc gtgtaggtat ccgtattgca gacttattag ataaagaaat ttttgaagaa
    12721 cgtcttcgtt tgaatctaga tgacaaaaac cgtcaatttg taaaaatgtt tgattcagaa
    12781 ccacttgatt ttgacgatat ttttgaagaa tattatgaat acggacaaca aatcaaacaa
    12841 tacgtcacag atacttccgt tatcttgaat gatgctttgg atgcaggcaa acgcgtgttg
    12901 tttgaaggcg cacaaggtgt aatgctggat atcgaccagg gaacttatcc ttttgttact
    12961 tcttctaacc cagtagccgg tggggtaaca atcggaagcg gtgtagggcc ttcaaaaatc
    13021 aataaagttg tcggcgtctg caaagcctat acgtcacgtg tcggtgatgg accatttcca
    13081 actgaattat ttgatgaaac aggagaacaa atccgcgaag taggacgaga atacggtacg
    13141 acaactggtc gtccgcgtcg tgtaggctgg tttgattctg tagttatgcg ccattctaaa
    13201 cgagtttcag gtattaccaa cctatcttta aactcgatcg atgtattaag tggattggaa
    13261 acagtaaaaa tttgtacggc ttatgaatta gatggcgaac taatctacca ctatccagca
    13321 agcttgaaag agttgaaccg ctgcaaacca atctatgaag aattgccagg ctggtcagaa
    13381 gacattacag gatgcaaaac acttgcagaa ctgccagaaa acgcacgtaa ctatgtacgt
    13441 cgtatctcag agcttgttgg tgtacgtatc tcaacatttt ctgtcggacc tgatagaaca
    13501 caaacaaaca tcttagaaag cgtctgggcg caaatctaag gataaaaacg acgactgaat
    13561 caggacgttc ttaccagagc gagtcgaagt gtttatctat acgataataa taacttgaag
    13621 aggtagtgaa agagacgttt agccttattg ccgataggct gtctcttgaa cactgtttat
    13681 tcagaataag ggactgtgac aaaa
//
LOCUS       DAFLVO010000074        13600 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.074, whole genome shotgun sequence.
ACCESSION   DAFLVO010000074 DAFLVO010000000
VERSION     DAFLVO010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.074"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(217..909)
                     /locus_tag="L1U99_002304"
     CDS             complement(217..909)
                     /locus_tag="L1U99_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1212831.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(1346..1915)
                     /locus_tag="L1U99_002305"
     CDS             complement(1346..1915)
                     /locus_tag="L1U99_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBN1212832.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1989..2312)
                     /locus_tag="L1U99_002306"
     CDS             complement(1989..2312)
                     /locus_tag="L1U99_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212833.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2466..3278)
                     /locus_tag="L1U99_002307"
     CDS             complement(2466..3278)
                     /locus_tag="L1U99_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212834.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3632..4480
                     /locus_tag="L1U99_002308"
     CDS             3632..4480
                     /locus_tag="L1U99_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBN1212835.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4625..5566
                     /locus_tag="L1U99_002309"
     CDS             4625..5566
                     /locus_tag="L1U99_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HBN1212836.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5556..7727
                     /locus_tag="L1U99_002310"
                     /pseudo
     CDS             5556..7727
                     /locus_tag="L1U99_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(7839..10010)
                     /gene="copB"
                     /locus_tag="L1U99_002311"
     CDS             complement(7839..10010)
                     /gene="copB"
                     /locus_tag="L1U99_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HBN1212837.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIR"
     gene            complement(10030..12216)
                     /locus_tag="L1U99_002312"
     CDS             complement(10030..12216)
                     /locus_tag="L1U99_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBN1212838.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEVKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLCLNRHMKK"
     gene            complement(12216..12425)
                     /gene="copZ"
                     /locus_tag="L1U99_002313"
     CDS             complement(12216..12425)
                     /gene="copZ"
                     /locus_tag="L1U99_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HBN1212839.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(12438..12878)
                     /locus_tag="L1U99_002314"
     CDS             complement(12438..12878)
                     /locus_tag="L1U99_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HBN1212840.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYYPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(12952..13491)
                     /locus_tag="L1U99_002315"
     CDS             complement(12952..13491)
                     /locus_tag="L1U99_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBN1212841.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQLFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
BASE COUNT         3826 a         2840 c         2415 g         4519 t
ORIGIN      
        1 taagctattt gtttacttct gtagaatata tactttgttg ttagataagt tgcacatgtt
       61 tatagaatct aaataataaa tttttatgta ccgcccctca aagtgaactg aaccccaaaa
      121 gttgaactat ttaatggact gtttccgata ttctactgga gatagtccat taaatagttc
      181 aacttttggg gttcagttca aagagggggg gattttttat cgttgtggaa tatttaaata
      241 ccaacgcttg tcatgaaaat cttgtgctcc acccttagta tttccttctg gatcgtttgt
      301 cgcacgcatc atgacgtata ctttcttatt agggaaatca cgcatattga aagatacatg
      361 atagccaaca tttcctaaag tattataagc ttgatttacg tctggtctat aaatcccatc
      421 agctcttact ctagctagtt cttttccagt attgtagtcc ataatgaaaa tatactcgta
      481 tttataatta gcaatgtgcc atccagctac atgcaagttt gcgttttcga tttctccgaa
      541 ctgatcaatg tgggcgtaat ttgttccatc tgtcagcgta gaatttgcag cacctgctcg
      601 agttggatca attactggtt tatcctccga agtagttgga ttatcatccg taaaaccatg
      661 agccaaatca taggctagtt tttctttact tacacccatt tcagaaagat aaccgtaagg
      721 atctgtatga tcgccccaaa tattttgtgt tacccataaa tgcgatttga ttcctggttg
      781 gttataagga gtgtctaatg ttaatggaat accatatttc attgctgaat ctcttgccaa
      841 ttcaacgtat actttatagt tcttttcaaa agtttcttta tcatgtgtat gttgtaactc
      901 gatttgcaca ggacttttgg ctcacgaggt tgtcctactc tacatcttgc tgatagatat
      961 gctgaaagga aaacaccaac attatgtttt gctttttcag ctagaacgag acaagcagga
     1021 atacctttag aagatatcaa aggtttttta ggtcataaag atgtttccac tacacaagtc
     1081 tatgcccata tttctcccga agtgaaaaaa agatcaatga atcaactaga aaactatata
     1141 gaagagcaaa taaaaaagca ctcaaattga gtgctttttt aagctcacta tcactaaaac
     1201 tatcactaat tttatttata agcgaacatg tttctatcac tgatttttta aatctagcga
     1261 aaaaccctta tcttaaaggc gttcgttcaa ttctttggca aggtcttcaa agcctggctt
     1321 gcctagaagt gcgaacatgg ttttcttata gctcatgtag aaaaattttc ttgatgatga
     1381 ttttatccat caattgagat tgactgtttt gctctcctat gatttcagct atgattgtcc
     1441 gattttgcgg ttttcttctt aactggtagt tgattttccc agtttccatc aactcgctaa
     1501 gcatatccac gactccgcca aatccggtct ttttcgtaat aaaacctagt gctaccattc
     1561 gttcatctag attttttgct gtaatcgtca caccagtaat gagcgagtgc tgtaatgttt
     1621 gggccagctc ttccatccct tcagcattgg atacgacgga agctgttttg ttaataggtt
     1681 cttcgtttat ttcttttggt tctttcctct ccactttcac tgtttgacga aggacatcta
     1741 gttcttgcaa gagcgtttcg tattgttctt gggtcagcat cacgccagct actttttcac
     1801 gattaaatat atatacgcca gttcccgcgt ctcgcgcttg agcaaataca tccatcggcg
     1861 atcgtttcac ttctgtgatc gaagatgtgg gaacttctaa tttctttaat tccaatggat
     1921 ttcctccttt actaatcgct ttttattata gcacagactg acttgttttg atcttttttc
     1981 caaaggtttt atcggttttt gcctaaccag taattgatat cggtaagaag tctttcgata
     2041 ccaaatgaag gatggtacag atacgttttt tgatcttcgt tatggtctag tggaaaaaaa
     2101 tgatcgatga tcactagatc tgcataccga ggcggcttat ttcgagtaca tacatgtata
     2161 gagatccgtt ttcgatgtct tagcgttttg ttcagtaccc cagcaagtct tcttgcttct
     2221 tggtgttcat agcgaaaaaa aaagacgatt ttcacttcag gagggtggac atctaaatac
     2281 cctcgttcct ggagtgtttt cagtaaaagc atcccccact ctactgcggg gtgtgcaagt
     2341 gcttgttgga tcgctagccg aaattgatat agtttatctt tggaattggg aaatttttct
     2401 aatgtttcct gataataacg aacttcttct atcagccggt catggatacc aattacgtaa
     2461 cgaagtcatt cttggtaaag tacttttgtc agctttgatt tgctttcgct ctcaaattcg
     2521 ctattcagcc aaaacagcga atcaagcttt tcagtcacaa tcgtcaattt ccgatagtct
     2581 tgtgtctctt ctatccgttt ccaccgcttt tcagtaatct ggttacagct caagcgcaaa
     2641 attgctagat aatttttttc ttttattggc aaaatctgct cctctctaaa tagcaattca
     2701 ggaaacaatt caaagaatag tgttcgactg tctcctaaaa tctcgatttc tgccggatcc
     2761 tttctttgct tcaataattg gatgaacatc tcagaaaagg actgctctcc atcatctgca
     2821 aaaaaatgcg gaaaatcttt caaaaagcaa aacagcagat atcttacttt tctttctgaa
     2881 ccaaagatct gtgctttttt ataagaaaaa gaaaggtggt actcgccaaa ccactttctc
     2941 aatcgctctt gcgtagaacg atcgtacttc tgctcgtaag gttcattcaa tagcagattt
     3001 ttcagtaaac aaaacggggg tgattggatc agaaaaacaa acaagagata aggttcgcta
     3061 tatccttgat cataaactaa ctgaacggtt ttcttatgaa gaatcagctg aatgggacag
     3121 tcgctttccg ccaaacgttt cagatgccga tccactgttt taacatcgat tttcagttct
     3181 tcagctaaat cagcttttcg ccagatcaaa tctttcatta gattgattag tgaaaataaa
     3241 ttctgtgcat tttttgataa tagtttttgc catctcatcg atcatttctc acctgatttc
     3301 taaacatatt gtttgatcaa aatgggttca ctcctaaaaa gataaaaaac tccctttcta
     3361 tttatttaaa tacgcaaatc ttcctcatta ttttttattt tactcaattt aatcgtattc
     3421 tcatttcaaa acgaatgtac tttaaaaaaa cataataaga tcactttgct tgtaggatgt
     3481 attcccttcc attacaatga aataaatagc gattttatga gaaggtgatg tgaaaatgga
     3541 agaaaaaata gaagaatcca aacaaaaaat cgatcagttg atataagaat tagaaaaagc
     3601 ggtcatcggc aaacgttcaa ctatccaatt gatgatcgtg gccctattag caggtggtca
     3661 tgtcttattc gaagatattc ccggtgtagg taaaacgtta ctggtcaaag cactagcaaa
     3721 agctgtacag ggaaccttca gcagagtcca atgtactcct gatctgctgc ctagtgatat
     3781 tcttggtttt tccgtataca attcacaatc aaaagagttt gaatttcgtc cgggaccgat
     3841 ctttaccacg atcttgttag cagatgagat caatcgtacg actcctcgta ctcagtcagc
     3901 acttttagaa gcaatggccg agaatcatgc aacgatcgac aacaatacat accctctaga
     3961 caatcatttt tttgtcttag ctacgcaaaa tccaatcgag tacgaaggaa catatccttt
     4021 gccggaagca cagctcgatc gttttttatt ccgactacaa atcggttatc cttcttttga
     4081 tgacgaactt ttgctacttt tggataaatt cgaaaaagtg ttggataact taaatgaagt
     4141 attgaacagt tatgaaatag aagaaataaa aacaaatgtg gcgaatgtct ttgtcagtcc
     4201 cgaagtggca tcttatgcct tgcagttagt gtcagcaaca agaagtcatg ctgccatcca
     4261 gcttggcatc agtccacgag gaagcctttc ctttattcag gcagcaaaag cttatgcttt
     4321 aatccatggg agaaattacg tcacgcccaa agatttgcag gatttagttc cttacgtgtt
     4381 ttcccatcgc ctgatttttt acgatcgttc attgaaggaa gacgaaaaga aacaaatcat
     4441 tcatactctt gttgcacaaa ttcctattcc tgtgaggtag attgaggtag acaatggaaa
     4501 aaatcaaaga ttatttcatt aattttgtgt tatttctggt atatttcatc attgtgcttt
     4561 ttgctcttgt attcaacaat tctttaggct ggttcttgtt ggcctttttt actctttatg
     4621 tatcatggag cttgatttca ttaagcagct ttctaaagaa actttcggtt acttgtacat
     4681 tgcagccact cgtttatcgc aaaaaaagta tgcaggttat tttttccata gcaaaaaaga
     4741 gaactttttc tttacctctc cctcgtttac aaatcggctt cccagcaatc tttgcagaaa
     4801 aaaacaagag attttgattc ttacaaataa accgcaagaa gtccaattgc tttggcagcc
     4861 aaaagaaaga ggatgccatg aaacattaac tgtcattttt acagcctatg atagtctagg
     4921 acttttcaga aaaagtgcaa aaagagagat ctcttttcct gtgactgttc tgcctgcttt
     4981 ttgtaagatt caagcagaaa aattacagag agttctggaa aaaaaacagc agctgaacgc
     5041 gtaccaaaga ggtcttgatt ttcgggaaca tcgcgcttat cgtccaggtg attctttcaa
     5101 ccgaatcgat tggaaattgt ctgctcatac tcaagagtgg ttataccgtg aatacgatta
     5161 tcaagaagaa gaatgttctc ctcttttttg cttttggggt tcgcccagtc caaaatttga
     5221 acctctgcta gacttgtatt tttctttatg gcatttgaga aaagaaaagc agccggaact
     5281 tctgatatta ggcaaccgcg cctttcatgg caaagacccc ggtcatacct attttgcttc
     5341 tttggaagct ggcgatgaga aagctttttt cgcacacttg aaaaaatatg caaaaaaaca
     5401 aatcgtcctc tttgttcctg agaattctcc tgaagtctca gaagctattg aaacattgtc
     5461 aaaagatcga acggtttatc ttgtttattt cgtagaaaaa caactcatgg tccaagaaaa
     5521 agacaagata tgttcattgc caggaggtga atggattgac gattaaacgg gaaaaatggc
     5581 tgcgtggcgt ttactccttt gtgatactaa gtgtaggtgc tccgatattt gtagtagcta
     5641 atcaattgca aaacagctac cttcttatcc taactattgg tgtcctatgc cttattgtct
     5701 gctgtattcc taaaaaatgg gtacgtttgc tgctttcttt gccagtaatg ataggttgtt
     5761 tgtttttata ttttccttcg aagacatttt ccatattatg gatcttacag tttttttcgt
     5821 cagtcacaga ggaattcttc catctatccc aaggtaaact ttattatttg ccagaaaaga
     5881 cagctttttt tctcataatg ttgctgatct atttatttat tacattgacc gtggattacg
     5941 actattggta cgcacccttt ctttctttga tggcttactt catgatgctt accgtttttc
     6001 ggaaaaaaga tttactgtac gaaatgattg cggtagtaac tgttttgttc gtgtatctgg
     6061 cagcaaggca atttttctcc atccggttgt tgtcgggaaa cactcgattc cagtcattga
     6121 ctacagttct gcttatttgt ttcttaactt ttagcgctat cttgccttta tatcttccga
     6181 aagtacacca atctctcgag gaaacgagtg aaccgatccg agaatatctt aatgatgaag
     6241 ggctttatga cacactccat gagtatcaat taaccggaag tgcaagaaca ggcttcagtg
     6301 agaatgatga acagcttggt ggacctttat atgataatgg cgaagttgtt tttacagcga
     6361 accaaaaagg aaatggctat tggaagatcg aaaataaaaa tcattacacc ggttctggat
     6421 ggatagaaga tcaggacgca cccatccaac caatccaaga attccctgtt gacatcacga
     6481 gctaccaaac cgttatagaa gacaaagaaa acattacatt gaccctaaaa aaacaagttt
     6541 tcttacctta tccttatgga aatactacct tgactgattt ttcattagct agtggacaaa
     6601 cgctttacta tttgcctgaa agccagcgat tcattcctgt cccgaatgaa tcgacacgtt
     6661 ctgcaacttt acaaacagaa aggttagttt ttacgagaga agaattaaaa agcagtcagt
     6721 taaaagctga tgatttagaa aatcagcaga caaatcttca attgccaaaa agtttgccta
     6781 aacgtattga ggacttggcg gtcgaattga ccaaaaatga agcaacttta attcgtaaag
     6841 tcgaagctgt ctaacagtat ttaaaaacaa gcggaaattt ccgctattcc aaaacggata
     6901 ccgggcatac tccaaaagaa cacgattatg tggattattt cctctttgat tcaaaagtcg
     6961 gctattgtga caacttttca acttctatgg tcgtccttct tcgaacactt ggtatcccag
     7021 ctcgctggac aaaaggtttt acaaatgggc tcagaacagg cacagataat caagggaatg
     7081 aggaatacag cattctcaat agtcatgctc attcttggcc agaggtatac tttcctggat
     7141 ttggctggct tccatttgaa ccaacccctt catttgccaa tccaatgggt tcacaaccag
     7201 ttgctgaaac aaccgaaacc gtccagcctg ctatcgaaca accaaatgaa agcgaaaata
     7261 tggcagaaac tatttccagt gagagatctg aggtcattcc atcagaagaa acaacactca
     7321 caccagctta taaaatcgtc ttattcagcc ttggagtgtg tttatccgtc ttgttgttct
     7381 ttctattgtt attcagaaaa tctctgcgct ggacaagtta tcttatctat cttcattttt
     7441 ttgcttctac taatacgatt gcatatcaaa aacttcttaa ccctttggaa acattggtac
     7501 cgcgcaaacc cgcagaatct ttgcaggaat atagcctgcg aatagaacaa gaattcaagc
     7561 tagatctgcg tttcattcga ttaactactc aatatgaagc agaaatatat ggacgacaag
     7621 cagatccggt aaaattcgat aaaaaaacct atttagaaat aacgcatata ataagaaaaa
     7681 tggtatacaa aaaaattctg acaaaaggga gccgcttcaa aaaataagat aaaatttctg
     7741 gagaatctac ttctggaatg ccgagaacca gctgattgag tatcgattac tcgaaaaaaa
     7801 ggttgtgaca cgttttttgt cacaaccttt tttcattatt atctgatttt caatgtcaaa
     7861 gcatttagag ctacaactac cgtacttaac gacatcaaga cagcaccaac tgctggactt
     7921 aatatgatac caattggcgc aagaattccg gctgctagcg gaattgcaag aatattgtaa
     7981 cctgcccccc accagaggtt ctggatcatt ttctttcgcg tttgcttggc tagatcaaga
     8041 aaatgcaaaa tatcttttgg atcgctgttt gtcaatacga catccgcaga atcgattgcg
     8101 atatctgtcc ctgcaccgat tgccatcccg attgaagcac gggctaaact tggcgcatca
     8161 ttgatcccat cacccaccat gattactttt ttcccttggt caaggtattt ctggacaaca
     8221 gcttctttat catctggtaa taaaccgcca taatattctt cgatccctaa ataatctgct
     8281 actgcttggg cagcgttttt attgtcacca gtaagcatga caggagtgat ttttctttct
     8341 ttcaatgttc ggataaattc ttttgcttct gtttttacta cgtcacctaa agcaacgatt
     8401 gcagctagat gattttctaa aatcaggaag ctgatggtat ttccttgttc ttggtaaggt
     8461 ttcaataatg cttgttctac gtttaatccg agacgctcaa cttctttttc attaactatt
     8521 ttcacttgtt gttttttgac tgttgcctct agcccgactc ctgaaagatt ttttagattt
     8581 tcagcttgat aaggcttgat ttcatgttct ttcaaataat tcataatgcc aacagccaat
     8641 ggatgattgg cattcgcttc caaggctcct agatattgaa ggatttcatt tttattgaac
     8701 gcatcatcaa gtacttcgac acccgttaca gtaaattttc cttctgttag tgttcctgtt
     8761 ttgtccagca tgatcacatc tagatcattg gcttgctcca gtgcattgcg gtttttcaaa
     8821 agtaatccgt ttttagctgc tattgatgtg gaacgagcaa caactaatgg gatagctaaa
     8881 cctagagcat gaggacaggc gatgataaag actgttacca tacgttctaa tgcattagga
     8941 agatctgtca agaacaacca ggcgatgaat gccaggatac ccacaattaa tgcgacataa
     9001 aacagccatt ttgccacttt gtcagataat gactctagct tggatttttc tccttgtgct
     9061 tttcgcacca tttccataac cttcgctaga taaccatttt caccagttcc agttacttcg
     9121 atttcgatcg ttccatcccc attgatagaa ccgccaatca ctttgtcatt ggcttgtttt
     9181 ttgattcctc ttgattcgcc agtcacagct gattcgtcaa caattgtttc acctttcaag
     9241 attacaccat ctgttggcat tttatcacca gaccggacga tcaaacgatc accttcgttt
     9301 acttctttca atgaaactgt ctcttctttt ccatctttcg tcaagcgttt cactgattct
     9361 ggcagtaatt ctgctagttt ttgtaaagca ttgctggcat tcgacacagc attcatttca
     9421 atccagtgac ctagtagcat aataacgatc aaagtagcca attcccagaa gaaatccatg
     9481 acgtgtgtat gtggattgag cagatttgcg ataaacgaat agacactata aatatatgca
     9541 actgtaatcc ccatcgcgat cagtgtcatc atagcaggac ttttttgttt caattccatc
     9601 ttagctccac ttaaaaatgg ctgaccgcca tagataaata gtatagttgc taagatcaat
     9661 acgagccaat cagaaccagg aaacgttact tgaaatggaa attccattcc catcattggt
     9721 gaaaaaagaa tgattgggat agctaggata agcgatagcc aaaatttttg tttgaaattc
     9781 cccatgtgca tggaatgatc catgccgccg tgttcgtgat ccatgtgcat cgaatggtcc
     9841 atttgtttgc tgtttgctat atctccatgg ttatgtccca tgtgcatgga atgatccatc
     9901 tgactatggt catgtttcat ctccatctgt ttttcatgag attctgtact ttctttgttt
     9961 actacttctt ttttatgctc atgttttttc tccatatcgt tcccattcat ttttactcca
    10021 tcccttctct tactttttca tgtgtcgatt taagcacagg gagttcaaca atacactgac
    10081 ggaactaaac gccatcgctc ctcctgcaat gattggattc aaaaagccta gtgcggcaaa
    10141 aggaatacca atcgtattat agacaaaagc ccagaaaaga ttttgtttga tttttctcaa
    10201 tgtcaaccta gacaactcga ttgtttgtgc aatggatgcc aaactgctat tcatcagcgt
    10261 cacatcggct gtttccatcg caatgtccgt tccacttccc attgccatac cgacatcagc
    10321 taatgctaag gccggtgcat cattgattcc atcgcctgcc ataccgactt ttttgccatc
    10381 tttctgaagt ttttctacgt aggctgcttt atcctctgga agtacttcag caaagatatg
    10441 ctttggatca ataccaactt gtttaccaat cgtttcggct gccagtttgt tgtctcctgt
    10501 cagcataaaa acatctaatc ctttattctg gagctgcttg attgcttgtt tgacttctag
    10561 tttgatttga tcagccacgg caatcaaccc gatcacttgc ttttcatcag ctaaaaacat
    10621 gactgttttt ccctgctgtt ctaattctaa cgcgtgttct tggtattcat caaatgatag
    10681 gttcaattca attaatcgtt tacgtgtacc cgcaaaatag cgtactccgt taatcgtacc
    10741 gctgattcca gcacctgggt gggctgtaaa atcaatcata tcgtatgttg ctgcttcttg
    10801 cagttttccg tattccacga ttgctttacc tagtggatgt tcagaagctt gttctaaagt
    10861 ataaaaaata gataggactt ctttagaacc gactagatct gtaactttgg gctttccttc
    10921 tgtaatcgtt ccagttttat ccaaaacaat gctgtctaag tgagcagctg cttctaatgc
    10981 ttctccgcct ttaattaaaa ttccatttcg tgcaccaaca cccgttccta ccataatagc
    11041 tgttggagtc gctaaaccta atgcacatgg acacgcaatg actaatacag agacactatg
    11101 gatcaatgcg agttgccaat caccagtgat caaacctgta gctatgagcg tgataaacgc
    11161 gatgactaat acgatcggaa caaaaatccc tgagatccga tctgcgattt tttggattgg
    11221 ggctttgctc ccttgagcat cttccaccat ttgaatgatt tgcgctaata ctgtctgctt
    11281 gccgacttgt gtaacttcca tgtgaagtag accattcgta ttgattgtcc cgccaaagag
    11341 cgtgtcatcc ggattctttt ctacaggaag attttcacca gtaagcatac tttcatctat
    11401 cgcactgctt cctgaaataa ttcgaccatc tgctggaatc tgctcaccag gacggatgac
    11461 tagttgatca ccaacgacta cttcttcaat cgctaacgtt tcttctttcc cgtttcttat
    11521 cacttgggcg gtttttgttt gaagagacat caattgtttg attgcattac ctgttttcgt
    11581 ttttgctgta tgttccaaat atttgccgag caaaatcagc gtgatgatca tactgctgct
    11641 ttcaaaataa agatcttggg ggtgtccacg gaaaaatccg ttgtaaatgc tcaatgcaaa
    11701 ggcagccgat gttccaattg ctaccaatac atccatattt ggtgctttcg tcttgattgc
    11761 atggtacgca cctttataaa aacgagcacc gacataaaat tggacaggag cagacagcac
    11821 taactggacg attggaaaat gaaaaaagtg aacaatcgcc gcatggcttc ctaacatcat
    11881 agcaatcatt gacaacatca acggcaaagt caaaaccgta ctcaatataa gatcgaatag
    11941 catttttttc aaatacgctt gcttttcttc tgcaattttt tgtttgtggg cttcatcgta
    12001 caaaattgca ccatagccga tgttttctac gctttggatt aatttttcag tggtcgtccc
    12061 ttcatatttg acacttgctt tttcagtggc caagttgact gtggcattga ccacaccagg
    12121 ttgtccgttc agctcttttt cgatcctagc agaacaattt gcacaagtca tacctgtaat
    12181 gacgaacgta tccattttgg tttctgctgt tgccatcaaa tcacctctgc tttataaccc
    12241 aatccattga ttgcttgaca aatcttttcg gattgaactt ttgtttcatc aaacttgacc
    12301 gtaccgtttg cttttttcaa atttactttc actttttgca cgccgtcaag tgcgcttact
    12361 gtttcttcta ctcttgctgc acaatgattg cagctcatac cttcgattga aaattgttgt
    12421 ttcatttttt cttcctccta ttgatgttgt ttacattcac attgacctgg gatacagtta
    12481 cattcgatcg tatctactgg ttgcttttgt tccagttgtt tcaaaatctc attgatatct
    12541 tcttgagtca aagtggcttc ttctactaga tccgcaatcg tctctccaat cctttttgca
    12601 cagatatggg aaaaaagatt ttccgtcgca ctgcgaactg tttccatctc cgagacagct
    12661 ggataataaa tgaatttttt tccttcttgt tctgtccaga tcacttcttt ttttaccaaa
    12721 cgacccagca aagttttgat cgttgctggt ttccaatcca tcgaatcagc taagatctgc
    12781 gtgatttctt gggctgtcgt ctgtccaagt gtccaaataa cacgcatgat ctcccactct
    12841 gaatcactga tctttactgg cgttttgact ttttccattt atttcacacc tttcgtttac
    12901 aaatgtaatc attatcttat gaatacagat tacacttgta aacaaaaact gtcaattatt
    12961 tttgctctct attttcaatt tagttaaaaa ttcttgtttc tctcgtcttg ttttaaggat
    13021 gatcagttta tttcttgcat tagctacttg gatcagctgc tgtattttcg gttcattgtt
    13081 ttcttcaaaa tgccagataa aagataaaaa ttctaagtat tccctgttta gtttctccga
    13141 aaatgattca ggcatatctg gccgagattt tttgtttatc tttcttttta gagaacgcca
    13201 aactactcgg tagatggcga gataacgcgg cactttaagc caaatgatct tatctgcttc
    13261 tttaatcctt tcctctaatg tagaagtata atttccttca acgatccatg acggattaga
    13321 taccataaac aattgctgtt cttgcaaaaa ccactttttt gcctgaatac tgtagtctgt
    13381 tgtatgccat aaaaggtcta gcggcagtag cggaaagtcg gtgatttctt tgatcttcct
    13441 tgcgagggtc gattttcccg acccactttg tccaatcacg atgatcttca ttcttctccc
    13501 tcacttctct ttggaatttg gttcgatcat accacttata acgccgcaaa aaaacaaggg
    13561 actgtgacaa aagtcgtgtc aaagtccctt gtttcgaata
//
LOCUS       DAFLVO010000075        13482 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.075, whole genome shotgun sequence.
ACCESSION   DAFLVO010000075 DAFLVO010000000
VERSION     DAFLVO010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13482
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.075"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            79..1125
                     /locus_tag="L1U99_002316"
     CDS             79..1125
                     /locus_tag="L1U99_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBN1212842.1"
                     /translation="MTKPNHIESSKKEAPKTEGQTKTFSTPQQIESTESFQSQPILSG
                     NEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIAQAILESASGQSQLAQAPNY
                     NLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYENYEESFEDYAKLLTKGISGN
                     KDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNELIKTYDLTNYDKEVKGPQMS
                     KTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIHAVKAGKVVKAEFHYSWGNY
                     VVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGSTGNSTGPHLHLEICKDSSLS
                     QSMLVDPKTLLFGD"
     gene            1474..2106
                     /locus_tag="L1U99_002317"
     CDS             1474..2106
                     /locus_tag="L1U99_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HBN1212843.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            2694..4133
                     /locus_tag="L1U99_002318"
     CDS             2694..4133
                     /locus_tag="L1U99_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1212844.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            4428..4646
                     /locus_tag="L1U99_002319"
                     /pseudo
     CDS             4428..4646
                     /locus_tag="L1U99_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            4895..5110
                     /locus_tag="L1U99_002320"
     CDS             4895..5110
                     /locus_tag="L1U99_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212845.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(5327..5583)
                     /locus_tag="L1U99_002321"
                     /pseudo
     CDS             complement(5327..5583)
                     /locus_tag="L1U99_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5770..6681)
                     /locus_tag="L1U99_002322"
     CDS             complement(5770..6681)
                     /locus_tag="L1U99_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBN1212846.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(6700..7704)
                     /locus_tag="L1U99_002323"
     CDS             complement(6700..7704)
                     /locus_tag="L1U99_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBN1212847.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(7701..9824)
                     /locus_tag="L1U99_002324"
     CDS             complement(7701..9824)
                     /locus_tag="L1U99_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBN1212848.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(9829..12276)
                     /locus_tag="L1U99_002325"
     CDS             complement(9829..12276)
                     /locus_tag="L1U99_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1212849.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(12263..12652)
                     /locus_tag="L1U99_002326"
     CDS             complement(12263..12652)
                     /locus_tag="L1U99_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBN1212850.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(12712..13215)
                     /locus_tag="L1U99_002327"
     CDS             complement(12712..13215)
                     /locus_tag="L1U99_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBN1212851.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(13228..13452)
                     /locus_tag="L1U99_002328"
     CDS             complement(13228..13452)
                     /locus_tag="L1U99_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212852.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLSLFNRIVGA"
BASE COUNT         4124 a         2657 c         2465 g         4236 t
ORIGIN      
        1 tcaagtgaaa gtagtacgat ttcaagtacc gaatcttcaa caacttcaag tagtacaagt
       61 gaaataactt cttcgaaagt gacaaaacca aaccatatag aatcttcaaa aaaggaagcg
      121 ccaaaaacgg aaggacaaac aaaaactttt tcgacaccac agcaaataga atcaacagaa
      181 tctttccaat cacaaccaat actatctggt aatgaagaaa ttcattttga caaaaatgaa
      241 tctgtagaaa attttattat gaaaattggt gagtctgcga gaaaaattgg tcagaaatat
      301 gatttatatg cttctgttat gattgcacaa gcgatcttag aatctgccag tggtcaaagc
      361 cagttagctc aggcaccgaa ttacaattta tttgggataa aaggaactta taatggaaac
      421 tttgtcatta tggtaacaaa cgaagatttg ggtaatggaa cgctttatac gacccaatca
      481 aaatttagag tgtatgaaaa ctatgaggaa agctttgaag attatgccaa attattaact
      541 aagggaatta gtggaaataa agatttttat gcaggagcat taaaagctaa tagtaaaaca
      601 tatcgagaag caactaaatt ccttacagga cggtatgcaa cagatacaca atactatttg
      661 aagctaaatg aattaattaa aacctacgat ttaaccaact atgataaaga agttaaaggt
      721 ccacaaatga gtaagactgg ataccaagtg cctattcata attattcaat aaccagtttg
      781 tttggaaatc gtggaaatga atttcaccga ggacttgata tggcagctac acagggtgag
      841 ccgattcatg cagttaaagc tggtaaggtt gttaaagcag agtttcacta ctcttgggga
      901 aattacgtgg tgatacaaca cgaagatgga tcaaccgcgt tatatgctca ccagcaacaa
      961 tacctagtaa aaactggaga taatgttttg caaggacaaa taattggcta tgtaggaagt
     1021 actgggaata gtactggccc acaccttcat ttggaaattt gcaaagatag tagtctttct
     1081 cagagcatgt tagttgatcc gaaaacctta ttattcggag actaaaaaag gtaatcaatc
     1141 tgacaaagta acaagaaaat ggttggattc ttagaccttt gatcaggata ttgagactgg
     1201 aattgatatc tcgattacga tgggtttgac aaataaaaca agtccattat cgaatatcga
     1261 gtgtattatt gccgtcttta tgctcatatt ttgagcaggt ttcactagat gaaaacaatt
     1321 tatctatctt gaggatttcg tgtacgtatc gttcagtctt gtattgtaaa ttagtcataa
     1381 aatcagacta agaaaaattg gaaatatttt tttctgattt attaaaagtt aattgaaatt
     1441 atatggtact tctttcttgg gagggtaggt gcagtgaagg aaagatatgg tcaccttact
     1501 gttgttgagg agattactca taatggatat aaaaaatatc gttgcctatg tgactgtggg
     1561 aatgaaacga ttgtatatcg atcaaactta ctatcaggta gaaccaaaag ttgtggatgt
     1621 ggaaattata aaaataggca taaatataaa aatttgacaa ataaaacttt tggtaagtta
     1681 gttgcaatca agccaactaa actgcgaagt gaaggaactg ttgtttggga atgtcaatgt
     1741 ctgtgtggga gaaaaaagtt agtatcggca aagcgacttc taaaaggtga tgtaaaaagc
     1801 tgtggatgtt tgaaatcaaa aaagcatcac attgaaaata aaaaattcgg attacttact
     1861 gcaaagtatc ctttggacaa taactgttca tggaaaacaa aatgggtttg tcattgtgag
     1921 tgtggcagta tgtgtgagat aagttatagt aacttatttt ttggacatac tcaaagttgt
     1981 ggatgtttaa aaaggcaaga aacaaggaca tgtgttgaag ggacagtaat agagtgtcta
     2041 acgtcaaaat taccgaaaaa taatacaagt ggtgttaagg gagtttatcg ttctaaagag
     2101 aaatagattg cgtatataac tttaaaaaaa aagaggtact atttaggatc gtatgattct
     2161 attaagagtg cagctcaagc tagaaaagat gctgaaaata aattgtttca acctttgatt
     2221 gacaaatatc gaggtaatca ttaattattg tggataataa ttaacagtga tatataaaca
     2281 tctataatat attattcata ctattgatat ttagtataat cctatggaat tgaatatcat
     2341 agcaatgtat ttgaaaagca aattggaaaa caaataggtg caacaccata aatatgaaaa
     2401 aattgggaaa aagtagaatg gaaatttgct tacgtctcac gagatagctc acactattaa
     2461 tctgaagaac aatgaagtcg acttttagaa attgctagaa gaaagtaaag cgaattatca
     2521 ctagttacta tagagtaagt tcaaataaag catctccaac ttacatggtt acatgaggat
     2581 atcaaatcga aattactcaa gcttcctatg gctagagtcg cgagaagttg ttgggcagta
     2641 gacataggtt atattgttct tagctacacg atcattagaa aggaaatcct attatgtata
     2701 gttatcaaga agatgcaaaa gtccaaaaaa atcgctggtg gattttgatt gctatatcta
     2761 tgtttacctt catgtccaca ttggatggca gtattgtcaa tattgcacta cctaccatct
     2821 cagatgatat gggcatacca atgaatcaag cggaatgggt agtgtccgtt tatctgatga
     2881 ttgtctgttc ttgtttgttg ctgtttggta aaattggcga tagccgtggg aaaatcaaag
     2941 tatttcggat tggtacgctg atctttgtct tgggatcgct gttgtgtggg ttcaatcatt
     3001 cgctaggtat tttattgttc gcacgggtgg tacaagccat tggtgctagt atgactatgg
     3061 ctacaaatgc cggaatcatc acggaagtct ttcccataca tgaacgtggt cgggcattgg
     3121 gagcaatagg tgcgtttgtt tcattaggct cgattgctgg accaggtctt ggcggcttga
     3181 ttttgtccca attttcttgg gcgtacattt tttggatcaa tgtaccggtg ggaatcgtaa
     3241 cgatgttgat tgctgaaaaa ttcttaccaa aagatatcac catgagcggc catacaatcg
     3301 atggaggggg ctttgctgcc attgcggcta cgattatcag cttttttgga gcaatctttt
     3361 tggggcaaga aagtggcttt ttccatccag tcccccttgt actgttcgta atttcagtga
     3421 ttgcctttgt cagcttttta aaagttgaaa agaaagcagc ctctccattg atttctttcg
     3481 gtatttttaa gaacaagatt tttaccatga gcttgattac agccttgttg attttttctt
     3541 ccaacttctt tgtcaatgta gtgattcctt tttatctgca aaatgctcgc gggttgagtc
     3601 ctagctatgc tgggctgttg atgatggtct ttcctttgat gatggtcgtc ggggcgcctt
     3661 taagcggcta cctgaccgac cgggttggcc cggagatttt ggtattagta ggcttgggct
     3721 tattgtcggt aacccaggtc atgtatatgt ttttgtcagt ggactctcct ttgtggctat
     3781 acattgtcgc tactgccatc atgggtgccg gcaatgcctt gttccagtcc cccaataata
     3841 cgatggttat gagctcggtc actatcgaaa acttgggact ggcaggctcg atgaattcct
     3901 ttgcccgaaa tttggggatg gtcagcggga tttcgctttc tacgacggtc ttatatcaag
     3961 cgatgtctgc taagatgggc cagcaagtaa ctaactatat cgcaaatcgg ccggatgtct
     4021 ttttatatgg aatgaagatt acctttttag gcagctttgt tttgtgtttt gttgcctttt
     4081 tcctgactat ctggcgtatc aaaaaacaag gaggtattca gaaaaatgtc tgaaaaaacc
     4141 actgttgaag aatttttgga ggcctgcgta tgggtgagtg ggatttccat ggatgatgga
     4201 agatgaagtg aacttctaaa agccgaaaaa ctcaagtatt atcttcaaaa tactagtgct
     4261 caatgagatg cttgatttga tcacaagaag actgcgaaag ccgctggcaa ccgcaagcta
     4321 ggtatcccac cgatggacta cgttttagag gctactggtt atgaatacgg agccaacgct
     4381 ctcatctgca taagaataca tcacccagat tatgtaaaga ttttcgatac ttctgtcaaa
     4441 aaatcattaa gatagataaa tgatttccgt ctagtcaaat tggttcagaa tgtagacaca
     4501 cagatggtaa gaagtcactc acaattcgag aatggacttg tcctatttgc cgtatacatc
     4561 ataatcgaaa cgtcaacgat agtatcaata ttttgaccaa gggctatgaa tacaagcatt
     4621 gccttagaaa acatcaagaa ccttaggaac aacggggata gcttggttaa taagagatac
     4681 cgctgtttag gcttgcaagt atactctttt atcaagaatt ccgtggcttt agtcatgaga
     4741 ggcttaatac tatgaaaatt ttctttagca tttttgattt aggttccttt tctaattata
     4801 ataagatgac cactacagta acctactgaa atatataaac agccactgta gtaccatttt
     4861 caaagtagtc tatgagagga gaatcttcat tcttatgaac gctggaattg cggatatgaa
     4921 tttaataaaa aaaaccctta atgattttac ttccaattca atatcaaaag gtactggtat
     4981 caatttaagc acaataaaaa agctgaaaag tggtgaaaga tcagtggaaa agctgaatct
     5041 tttagatgct ataaaaataa cggaatttgc tatgaaaaat ggaaaagctg agattgaaat
     5101 atggagataa ttatcgtcta gtgaattact tgccacttag ctgaatttaa cgatccttgg
     5161 tgcttgaagg gggagattct tgggaataga gcatacttgc aagcctatgt ctttactaac
     5221 aacgatatct cttattaacc aagctatccc cgtagttcta aggcttttac ttttatctaa
     5281 gcaataatcg tattcaaagg aaatttttga cccttagaaa gtctcatttt atcagacgtg
     5341 agcttaggca ttgctgaatt ttgttaattc ggttttaggt tgtgctttga gcataatatg
     5401 aaagtattct ttatcacgat ttcattcatc taaggtaatg tgatgtgatt ctgaaattct
     5461 ttcaaaggca gtttttgcat aagctgacat tacatcatca atgacatgtt tacaatgttt
     5521 cactactaaa ataagggggt aaccaagaag aaaaactgaa tgattatttg tatctaattc
     5581 catggtatat caaccatttc ctatatagac tgattatgac atggattaaa ataaaaaggc
     5641 actatgtctt aattgtcggt tttcgagtta ccgaatggca ttcatcaccc acctatagag
     5701 gatgggcgac ttctgcctga aataagttac actacttata acttctaata aaattagatt
     5761 gagtcattat tatttaacat caacgatttt ccagtttcca tttttttgta atactaattt
     5821 gtactgaaag tagctagtgg tttttgatac attatcaagg tattttatct ttgtactcac
     5881 tagaaaattt tttccgtttt gtagataaac tggattctct aactccgaaa actttaagtc
     5941 aatattgatt ggtcgcatcg caccattttc aacataatac tccaattctt tttcagaagc
     6001 tgatggataa agtttaaaaa atgtttctaa aaaatcggtg atttcttccg ttgttttggc
     6061 atcaatttct gaatcgtttt ctacttgttt tgcttcatat tttgccttgt ctggctttcc
     6121 aatcattgtt ggcaaactag ttactaaatg attcctgttt tcatcttcaa agattgtcac
     6181 tcgatatgca gaagaaattg attgcgtctt ttttccctct gtaatatgtt gctccactaa
     6241 aaatgaaacg acaaattctt ccgagtgttt ttcaacatct agaattttta cagattgaac
     6301 ttcggaactc gtgggaatat ctgctcgaac catatcttgg attaaagcga gaccgttttc
     6361 tgtaaggtac tgttcgagat tactcattct cttttcaatt gcttctttgt tatttttcca
     6421 tgaaaaatat tctttcgcaa aatcctctgt aaaactttca acgccagaag tattcactac
     6481 cttctctttt ataaccactt tttcatgagt tgtatgttga tcaatggcgg tgaaattttt
     6541 ataaacgcca aaagcaagac tacaagacaa taaaagccaa agggcaagca ccatttttcg
     6601 atgcttaccc acggatacaa ctcgttcttt tttctttttt gggctctttt ccttttgatt
     6661 ccgttcaatt tttatcttca ttctttttcc tcttttctct tatttgtatc ggccagctcc
     6721 gataagatgc tgccgccaat agttttccgt tagattcgtc caccccactg gatctcctgc
     6781 atgaaacatg cgattctccc ctgcgtaaat gcccacatgg gtcacataag taccggcatc
     6841 ataggttgaa tgaaagaaaa ctaaatcacc tggtttggca tcttttagat caatatgagt
     6901 catggcatca tattgatcct gagccacccg aggaagtttc aggtcaactt tggcataaca
     6961 ccattgggtc aagccactac aatcaaaccc cgtttctgga cttgagccac caaacacata
     7021 ggccgttcct tcatacttaa atgcctcatc aaaaatttct tggactattt tgtcatcaaa
     7081 ctgagttgta gttaggtatt gcttcactaa taaacagtaa aacatattgc cataattata
     7141 ccgccaccca ccattttcct taatcgcgat tgggttgggg taatcgactt tttgaccacc
     7201 tgatttttcc tttgaaaaag attcagctaa agcaaaacta tgcttcttcc cgtttttccc
     7261 gacatgatct agatacccgc caccatagtt ataggcctga ataatactat cttgatcaca
     7321 ccctagttct ttggaacgct taaccaaaga cgcaaaatag agacagcctt gtttgatgga
     7381 tgcctcggta cttaatgaat taggtggtaa tccggctgac tcagaacttt gcataacgtc
     7441 ttccattgtg ccaccagatt ccacttgaat aatcgccaaa agaattggaa tatactctgt
     7501 tatatccgat tctttggcat acttttccac cattgcacgg tgtttcaata cttcttctga
     7561 gacactagtt ccgccaggag aagtgccaga actaccattt ccctcactgt cttcaccaaa
     7621 caacaaaccc acacacatca aaatacccat aaaagagatg gtcagaaaag ttaatgaaat
     7681 aacacccact ttcttcaagt tcattttttc tcacctgacc ttgattttgg acgatggttc
     7741 attctttttt gtactttttg attggtctgc tttggcagag tggacctctg tttcacttgt
     7801 tggaaagaat ttttcttact tgctgattgg cttttccctt ttgaaatgat ttcttgacta
     7861 gttagttttc gtttgatttc gggattcaga tttgctctca caatccgctt tggtgcttct
     7921 tttttcagca tcatatcttt ctgaggttga gctgctttat ctattggaat attcgccctt
     7981 ctttttccct gacgatttgt tgcttcactc agtatcttgc gtttttcgtc cattttcgca
     8041 tttcttcgtt gtcgttgttt ttctcgcaaa tccactcgat ccgctttttc ttggaacagt
     8101 ccgcgcttga attcttctgg tgcttttttc gacttttcga ttcctttatg gagattgtat
     8161 ttcaaattcg ttggcgtatt ccttacctga tcctttactt gtttagtctt atctttcacc
     8221 aaagcttggg tatccaaaac tttgccgatt tttctcccag ccaaattcat tcgggattgt
     8281 ttcttattat ttgaaactgg attctcctta gttaagtcag atagtatttc gtgatcgttc
     8341 ggtaatcgtg aattctttcg tagagaagaa ccggatggct taaatttgga ttttgattgt
     8401 tcctttgcca acttatttcc gactgctgca ccaccaccaa aagccaaagc tcgtcccaca
     8461 tttcgattga gttgccgcaa ttttcgattc attaacattt gcggttttcg catgacgcgt
     8521 cttcccattg actggctatc attactctgg aggttgaaca tactcataat gtcgcccaat
     8581 ttgaaataga taccggcaaa ggtcacaatt tgcagaaaag caaccatgaa aaatggatag
     8641 gttgccgaaa tattgaaaaa catcgtggag atgctaaatg cagtcgtaat caccaaagta
     8701 acacccgctc gcatcataat cgtattgaat aaacgaataa tcgccttctt tcctaaactt
     8761 tcataagtcg gcaacatgga caataagaaa ctaattggca gaaacatcgc aaagataatg
     8821 aagagaattt gcgagaacaa cataatccct gttagaagaa aaacaaagaa ggaaatgcca
     8881 atattgaaca ataccaaaaa gaccacggtc cctaaacggt tcatggtctt ggtaatactg
     8941 agattcgcat tgtcattgtc ttcaatctct gccttgaccg cttcttcccg atctttgcct
     9001 ttgttttcat ctggactcac agatagaatc ttgttgaccc ggtcttcacc aatttcttct
     9061 atgttggaat catcaaattg cagtagtaac caaggttgtt ggacttgaat cgaaaacaaa
     9121 ctatcccgaa tcaaatccac actatctttt ccttggcttt ctgaattggg tacaacgatc
     9181 tcggttccaa gggtaagggc cgcttcacta acatctgagc taaagtcatt gatttttgtg
     9241 atataggtag gcgcataagc aatgaacgaa cccgatagta gaaaaatcat cacaaaatta
     9301 atcacggctc gaactgcttt cgtggtttct cgttttaata atccggtata cgccacatac
     9361 acccccagag ctaaaatcat caataataga aacccaaaat aaaatccgga ggtctggagt
     9421 ccattttcag taataccagc caatgtttgg atattctttc caatactttc agccgtatcc
     9481 gaaatgaaat ctaatttgta agcctcttga accacataac ccgtggcgtt cgacaaatac
     9541 aaactcaccg tccaaatgaa attagtaatg gcataaagac catacatcac gcttttccct
     9601 aagccatcac cccaattcca aggcaaccaa tcccaagagc tatccacaaa gaaatctagt
     9661 tgatagttgt tcagtgaata tttggaatat agatttcctg cttcaactgt atcatcaact
     9721 agccctgtcg cctcggctac cgtaccaact aaactcaata gaactatcag agtgagtatg
     9781 ctaataaaaa cgattcccac aatccgaaaa agtttctttt tcatcccctc actccattct
     9841 ctcttgaaca ggtggacggg tatcaaaggc atggaagagt tcttcaaaga ctggatgtac
     9901 ctgaaccacg cctacccgac catacaaatc ctgcatcaag cattggccat tttccaaatc
     9961 tcgtaggcgt ttttgattgc tttcatcttc tcgatccaag ccaaagaatt ccaaggtttt
    10021 cttgatttca tgaatatcgg tactgcgaaa cgcaaacttc aacccgatat tattcttcaa
    10081 gcgttcatcc agtaaatcat cactattttg cgtgacaaag taaaccccgg cattcatagc
    10141 ccgcccagca cgaacgagct tattcgataa tgttttccct tgcgctactt gaagaaaact
    10201 ccacgcctca tctaagtcta caattttgaa gatttctcga ttactatgga taaagtccaa
    10261 ggcaaaagtg gaaatgacga ttagcatgga aacactaagc aattccatgg tggtatattc
    10321 ttcaaaagtg gtttctgcat ctggtaaaac caaatccgct acttgaatga tatttaactg
    10381 cctatctaaa ctaatcgact gggtaatcga accatctgag aaaagcaaat gggcaaaatc
    10441 ataatcggta aaggactcga tgtgatccgc gatattttcc gcaactggtg agccttcttt
    10501 tcgaagctca ttaattactt gtaataatcc ccgttgattg ctttgggtaa ccgtccgaat
    10561 ggccttacgc aacactggaa acttctcccc atctcgacta gaaattcctg ttaaaaaggt
    10621 cagaatatca attgctagac tttcagaatc cttctttttc tccataatca cataaggatc
    10681 aagtaatcct tgattttttg gcttactagt taagttgaga atattgattt catccgcaat
    10741 ttctggcaag gtttctttcc agccaccccg ttcccctttt ggatcgacaa tcacagcttg
    10801 tccaccaaaa aggacggcgt aataaactaa gagattgtta ctaaaggact ttccgccacc
    10861 gagtgaaccg aggaatgccg ctgctagcgc attggtaact gaatccttga ccccttgtga
    10921 ggccaatgcc ggtttcaggt aaacattgcg ccccgtatct acgttataac caaagtaaat
    10981 gccttccaac tcccctaaca tctgagtggc gccaaaacca agtccggcga gaaaatcaga
    11041 cgtaacatac tggatataat cattcatgta tcgcttacta gaaggtaaga attcttcatg
    11101 tagccccatc atatcgccaa aaggccggac tagttttaca ttggtatcat cataaaaatc
    11161 tagcacttca tcacaccggc gctttagttc atctactgat tcggcactta ctcgaaccac
    11221 atagctcagt ttgtacatgg attctttgga ctgatccaag gtagtttcca attcatctac
    11281 ggaatccaat gcatctaaga cattggaatt tgtttcattg tcagattgat aggcatggtt
    11341 gtccaagtct tttaattcct ttttcttatt gcgaacggta gcaagtgcct ttttgttcgt
    11401 cacaatctcc acattcatac tagtgtcaat tgggaatgta aattgttgtt gctggtaata
    11461 gaaaagttct gaggagggaa actccatttc ccccacaatt gtattaattg ttaagtacgc
    11521 tacatatgat tcatgattct catgttccat gcataagtac cggggctttt cttcaatcaa
    11581 acaacgactg ggacgtaata agtcgtaacg tttcaccaaa gtttccgact tcagcttttt
    11641 ctttggtagc tgaaattcat attcttcaaa tggtgtaccc ttttcgccat agatatgttc
    11701 aatcaaatac atcagatcac tcggtgtgac tcgtctgact ttaaatcttc gagccaattt
    11761 actttccatt agtttttcaa gcttggtata tcggcgaatt tcttcattgg ataaggaaac
    11821 aaaatcgccc atcaaatgat gattcactcc atagacaaat tcttgaaagc cggagaagaa
    11881 agatttcttg agattcttta gattgacctc ttcatctgtc gcaatcagtt tgaagccaat
    11941 aaaaaagcga taatcaatct gactatcgcc aatcatggat actaatgcct ctgtctgtaa
    12001 atcaattcgt tgtttcgcta cttctgttaa tcgcccggta atttcctttt ttgatcgttc
    12061 ttgcgtggca cgaatactac tttctgtggc aatttgtaag gcatgaatct tgccttcacg
    12121 attttgcgca atcaattgac gaaagttatc gtggacttga tatttctgtt caggtgacaa
    12181 aaaggagtaa ttgtaaggta ttaactcata gtaggcaaaa cattctccct cttgattaaa
    12241 gacaagatta ttttcaatat acttaatcgg gtacatagtt cacactcctt accagagtaa
    12301 tgggttcgtc ccatcgtttc ttctgttctt tgactttctt tcctgcgaaa gtgaccttaa
    12361 atcgtaagtg atagctaata aaagatcgta aaaatcccaa tggtttctta ccgtcaaacg
    12421 ttttttgcga catgaaccaa gtaactgcca ccggtatacc taagtatttt aaaaaggccc
    12481 cctctatcat agatagtgga ggcacatggg caaatacgat gacaaacagc aaggataaaa
    12541 caaaccaagc catctggtta aaagtcacag gaaaaggcag ttgaaagtca ttaattgcat
    12601 aaatgacctt ttcaactgcc caaatactgg tgtagctttt tattttcttc atcaaatcat
    12661 tcctttaaaa agaaggatag tttagaaatc aactaccctt caataatttt gttaatatgg
    12721 atactcaaaa acacctcgac tcgttaccaa ataattgcct ccaatctcca agtctctacc
    12781 acacgcatca aaatcaatat acgtcttcaa gtgttctggt acttctccaa aatcaccagc
    12841 ttctacaatc aagaaatatg ctacatcact catatcatcg caatctggat aatagataat
    12901 atcatccaca tgctctacca tctcctcaaa agaattgaag aaagcatgtt gaatctcaga
    12961 agcaacttca ccaactggcg ttccttcaag ttcctccgct aagccacaca accgattaat
    13021 ttcctcaatt ggcgtatact catcaatctc aaagggaagt tcataatcat gaattgcata
    13081 ttcctcgtat tcgtcattta acccaattcg ttctttcact tcatcaaaat cgacaggtgg
    13141 ggtaaaccac gcccccacca attcaccttc gttatatttc ccgaggttcg caatataaac
    13201 acgcatctgt tccatcgtgc ttccccctta cgcaccgaca attcggttaa acaaactgag
    13261 taagacatcc ttcaccccag aagcattaaa gaccaatccg accgcaatca aagcaatcac
    13321 caaaaagcca atcagtttgg aaaactcccg cttaaatcct aaaaacaaac caatgaccac
    13381 aattgccagt aagactaagg attgggcatt ggttaaaaac cattgatata tggataggta
    13441 agttcctgat attataaata tctcaaactt ttccccccat tc
//
LOCUS       DAFLVO010000076        13386 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.076, whole genome shotgun sequence.
ACCESSION   DAFLVO010000076 DAFLVO010000000
VERSION     DAFLVO010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13386
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.076"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(573..1187)
                     /locus_tag="L1U99_002329"
     CDS             complement(573..1187)
                     /locus_tag="L1U99_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBN1212853.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(1793..2170)
                     /locus_tag="L1U99_002330"
     CDS             complement(1793..2170)
                     /locus_tag="L1U99_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212854.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(2470..3351)
                     /gene="galU"
                     /locus_tag="L1U99_002331"
     CDS             complement(2470..3351)
                     /gene="galU"
                     /locus_tag="L1U99_002331"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBN1212855.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            complement(3394..4413)
                     /locus_tag="L1U99_002332"
     CDS             complement(3394..4413)
                     /locus_tag="L1U99_002332"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBN1212856.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            complement(5046..6050)
                     /locus_tag="L1U99_002333"
     CDS             complement(5046..6050)
                     /locus_tag="L1U99_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBN1212857.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            complement(6063..7112)
                     /locus_tag="L1U99_002334"
     CDS             complement(6063..7112)
                     /locus_tag="L1U99_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBN1212858.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            complement(7129..7950)
                     /locus_tag="L1U99_002335"
     CDS             complement(7129..7950)
                     /locus_tag="L1U99_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1212859.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            complement(7937..8716)
                     /locus_tag="L1U99_002336"
     CDS             complement(7937..8716)
                     /locus_tag="L1U99_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1212860.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            complement(8733..9203)
                     /locus_tag="L1U99_002337"
     CDS             complement(8733..9203)
                     /locus_tag="L1U99_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1212861.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            complement(9215..9634)
                     /locus_tag="L1U99_002338"
     CDS             complement(9215..9634)
                     /locus_tag="L1U99_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBN1212862.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            complement(9715..12492)
                     /locus_tag="L1U99_002339"
     CDS             complement(9715..12492)
                     /locus_tag="L1U99_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1212863.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            12683..12907
                     /locus_tag="L1U99_002340"
     CDS             12683..12907
                     /locus_tag="L1U99_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212864.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
BASE COUNT         3941 a         2777 c         2161 g         4507 t
ORIGIN      
        1 taaaattctt tttttatttt tagattagag aaaatctcgt cctgtttttt tcattttaca
       61 atcattgaaa aattgaattt cattgcaaaa aaaataataa acacttataa atatccatta
      121 tctatccttc aatttttgtg tattttattt ctattagaaa aaggtatcct gttggacaat
      181 tttgttatat caggtaaact tcattgcaat aatgataaca aatgtactat aattactttg
      241 taaagagttt tggggaagac tctttcatca acgtgtatta agagacaaga aagaatccat
      301 atggattctt tcttgtctct ttttccacta ctttttattt ttctgacact acatattctt
      361 ataactcatt tctcataact gtgaaacaac ttataaaaat aacaaacttt aaacaaaaca
      421 agcttaaaat caaagatgat ccatcttaaa ataactaaaa caaaaaaagt agtcgttgtt
      481 aatcctcatt aataatcgtt ttcttttttt caaacgctcc atttttatgt ggaacattat
      541 ttttttaagg aactttgtca acatgtggat aactattttc cacttgtgtc ctggactagc
      601 tgttttgctg taaaatacaa aacttgctgc agcaaaaaga tcgttgcaag agaggctgtt
      661 ccgcagatcg ctggatctag atttggcaaa gtcaagactg catcatgtaa attggcgtgg
      721 ttgtccaaaa ccaaatcagc aaattcaaat aatcgcaaac cactgctatg ttgcgatttg
      781 atacttcgtg acaaatcaaa tccagtaaca atgattaatg gatgaccatt ttctttgatc
      841 cactgagcta gttcgatgat tgccgggttt cttccttcat tcgaaagaag aagaaaaatg
      901 tcttctgatt tgacagaaag ctgatcaata attgcctgtc ctgcaccttc tagcgtttca
      961 tagacacctc cggctggatt ttcaatcaat atacttggta caagatccgg ggtttgatcc
     1021 caaaattcaa atgctacacc acttagtgtg cggctagcat atatctgcaa tctaccacct
     1081 tgattaattt gtttcgcgat ccaagtgcca gcttgaagca tcagcggctc ttctatcctt
     1141 aatttctctt ccaattggtg ataatagtca aaataacata aactcattta tctctcccgc
     1201 ctagctatac ttgacatgaa tagaaacagc tgcctaatct aaggaagtac ataaaaaaac
     1261 agtagttaga cagtaacaca tgtggtcttt gctgtttcaa acacaaaaaa ggcattgaac
     1321 gaatacgccc aataccttga catagcaaat aaaacaacgt gcagaccatg gaaaatatct
     1381 acataggggt agaattttca ccctagatta ggtacaataa attaggtcga tgcactgcat
     1441 tgactatggc aaaatgatcg gtcagggtgt atgtgtgtga ctggtcattc cctgattctt
     1501 agcgccaact aagggtcagg gagccttttt ttattcagct gtttctatct gaatttattg
     1561 taagtaatct cttatccaag tgcaagcaag aaaatacaaa aaaacattgg tatgatttat
     1621 atatatataa ataacataaa aaaaggaatg gcttatcccg atacaacaag cattccttta
     1681 aaaaagattc ttttatataa gtgaaaaaag cttttttcca ccaattaaat aaatctctca
     1741 tctcaatagt ttatccatta ttttatcttt ttttgcgtat acctactaaa tattaccgtc
     1801 ttcttctcgt tcttctactt tgttcgagag aatctgtact agaaaaagta gttgtatgtc
     1861 taccttttct gcctatccga gactttcttt tcatatatgg gatataaatg attagataca
     1921 gtacagcaaa aaataaagca aatacgcaag cttcccaact acctaacgcc aattcaacca
     1981 tcaaggtagc aaccccaacg gatgctgcat accagataaa aatcagaaac gtttcttttt
     2041 ttctgaccat gcgaaacatg ataaatagac taataagcaa tagtggcaac acaaatatcc
     2101 aattgcttcc ttccatcagc cacttgagta tatcaagcag cgactgtgca acagcgacta
     2161 attttcccat agtgaacaca cacctttttt tataattaaa aaattcgcct ttttattcta
     2221 ctatgaatct tctggcttgg ctttcatttc tcttatgtaa tcattttctt ttatacaact
     2281 taaaaaaaaa ttaaaccatt agcataatat tttctgaatc tattcacgaa agtctttttc
     2341 tatctttcgt tttccacgac tcaactgatc tagagtcaaa aaactaaaac gacagttgcg
     2401 caaatgacgc acaagctgcc gctttaataa caaatagcct ttcattctca gcaggccact
     2461 tatttccagt taactttctg ttcttagctt tttactcaac tggataatat atgcacttaa
     2521 tgaagtccca atttccgaat gttgaagtcc atattcaata tttgtcttca tatatcctaa
     2581 cttatcgcct acgtcgtatc tttttccttt aaactctctc gcatagaccg cctctgtctg
     2641 gttaagagtc tgaagtgcat ccgttagctg tatctcgttt cctgctcctg gttcttgagt
     2701 ttctaatatc tcaaatattt taggagtcag tagataacgt ccgataatgg ctaaattact
     2761 tggtgctttt cccatttcag gtttttctac aaaccctttt actctgcaac gacccttttc
     2821 gctatctgtt ttaggatcaa taattccgta tttagatgtt tcattttctg gtacacgcat
     2881 gacggcaaca gcggaagctt gtgtttcttc ataatccatc atcaattgtt gagtcaatgg
     2941 gatatcatct ttcatcaaat catcccccag catgacgaca aacggttcat ttcctataaa
     3001 tgcttttgct tgaagcacgg catcccccag tcctcttgga tgagattgac ggatgaagtg
     3061 aagattgact tgagtcgttt cttcaactaa agcgagtaat tctgtttttt ccttttcccg
     3121 caaattgttt tccaattcga tatttgcatc aaagtgatct tcaatgggtc ttttttcttt
     3181 tcccgttacg atcaagatgt cttcgattcc cgaatccaat gcttcttcca caataaactg
     3241 gatcgttggt ttatccacga ttggaagcat ttcttttgcc atggcttttg ttgccggcaa
     3301 aaaacgtgtt cctagcccag cggcaggaat gactgctttt ttgaccttca cttgctgttc
     3361 ctcctaaacg acgattaact attgatcatc tatttaacga agagaaaatt cattctccat
     3421 ttttccgtca cgtaacatga tttcttttgc tgcttttttg atatcttctc cattatacaa
     3481 aacattatag attgtttgag taattggcat ctcaacacct agctgttgag ctagctctac
     3541 tgctgctttt gtcgttgcca caccctcaac gaccattccc atgttttcta gaacttcttc
     3601 cagcttatgt ccctgtccta acaagttacc ggcacgccaa ttgcgagaat gaacacttgt
     3661 acaagtaacg atcaagtccc ccacaccact caaaccgata aatgtcagag gattggcacc
     3721 catcgcgaca ccaagacggc tgatttctgc caatcctcga gtcatgattg ctgcttttgc
     3781 atcatctccg aatcctaatc catggatagc gccggcacca attgcaatga tatttttcag
     3841 tgctgcacca gtttctacgc caatcacatc attatttgta taaatcctga aataatcatt
     3901 catgaacagt ttttgtacat aggctgctgc tttttgatca atacttgcag ctgtaattgt
     3961 tgtgatatca tgtactgcca cttcctcagc atggctagga ccagataata caacaattgc
     4021 ctgtcttttt tcttctggaa tttcttcagc caaaacttct gagattcgtt tatgcgtatc
     4081 ttgttctagt cctttacttg catgtataat gattggctta gtattcattt taccaataag
     4141 ttcctgtgcg actgaacgaa tcgcttttgt tggaacaaca aataaaatag catctgcgtt
     4201 atccactgct tctgccaatt ctttatatcc gataatcgat tctgggatcg tcaaatcagg
     4261 taaaaaatgc tgatttgtat gatacttatt gatttcatca atctgttcag gtacatttcc
     4321 ccaaatacgg acatcatgcc cgttttctgc caatgtttgt gctaaagcag tgccccaaga
     4381 tccaggacca agaactgcga ttttttgttt catggatatt cctccaaata aataattgat
     4441 aatttccatt atagtataca tttcttaaag ttgggactaa tttccattgt ttttaagtgt
     4501 ttgtttactt cttttatcgt ttttacttga aataatcaat gatatgttac aatagtctac
     4561 attttatttt tacactcgtt atgctttgct tgttcctaag aggaagcagt tttgacaatg
     4621 ttactaccag cattactatt aggaggttag gaaacttctc ctagtgagta ttgatttaaa
     4681 atacataaga gacagattga acatttctaa atctgtcagg tcctgcaacg gacagattgt
     4741 ctctgttgac ggttgacata ggaacttttg ttttagtcaa cattctggat acaaaacgct
     4801 atgtaaactg gcgcaactcg ttgtacttgg acttttacta cggatccatg caacaactaa
     4861 atagtactat tgcataacaa aaaatggttg gcacccacat gtcccattaa acagattata
     4921 agttgaactg tagataatgc aaaaaatgtg ttttataacg taattgatgc caatatttta
     4981 aaaaaataaa gggagcagtt atcgctgctc tctttatttt ttatattctt tttatccagt
     5041 ctatcctaat aatcaaactg acgatagtag cggcgtatct ctaatggatg gcagttcaac
     5101 tgctccacat gagcatcgat gcgttgtgtc actacatgca tcaataagaa agacaaaaca
     5161 cgtccgcgat atttttcact gataccttct actggatagt cttttgtgtc tatcaatgta
     5221 taattgctgc aaatttttgg caaaagttta gccacacgtt cagataacac tctctgttca
     5281 tcttcgccta aaaataatgt gactggggtt gtttcttcta cgatctctaa cgtcccgtga
     5341 agaaactcgg cagcatggat agatttcgat ggaagccagc tttgttcttc ccagtaacac
     5401 atggcatatg aataaacagc tccccattga ttccctgctc caataaaata atgcatacta
     5461 tcacgtcgat gtttttctgc aaatgataag ccaaatgcat ctgctttttt ctctgcttcc
     5521 actaaccctg ttggtaaata acgttcgagc tgttcatagt attctgaata agcttcgaat
     5581 tctccattca aatacatcaa tcgatctgct gccataaaaa atttgatttg ttctgttcca
     5641 ggagctggat aagtgaccac aaaatcgcat agctgagaca acttactgtt cgctttatcg
     5701 ataaatccaa tcagtgtcgc tcctactttc ttgatttgtt ctactgcttt cactacttct
     5761 tgagttgtac cggtaacaga ggacaaaata acgatagaat cttttgttaa tcttttgttt
     5821 ccagtagtgt aatattctgc agcatgctgt acaaagacag gcaagttgct tttcccattc
     5881 atataagtga cagcttgcat cgaggaagca tacgttccac cgattcctag ataatagaca
     5941 gcgtcaaatt tttccgcata aagtttatcg atgatttctt ctacttgcgg acgtaaagct
     6001 agtgcgcctt ttattgcttt gatttgttct tcttcattga atttcagcat gatttccacc
     6061 tcttataatt tacttttcaa gactgtatca aagtcttcaa aaatcttttt gttcaagtca
     6121 atacctttag ctactgcggt tttataagcg aatagttgaa acggaacgac aagcgctaat
     6181 acagacagat attcatcaca ttctattgct aatccaagtg ttttctcgtt tcttgctttt
     6241 tttgtggtaa tggtgagagt ctctccaacg taccgactca tatatctttg caacttttgc
     6301 gaacgttcct tatttacact ttccccttca ataaagaata gcaaatgcga agcatctgcc
     6361 tccaggtatg ggccgtgcat ataagcttct aactcaaatc cttgtgacgg aacgcggatt
     6421 gtttcagtca atttcgtctc tgcttcttta gctgttcccc agtttggacc atatccaatg
     6481 gtgacgaaac gctgtgctaa acgaaataaa ctttgatatc catcaaaaaa ttcttccgtt
     6541 ttttgaataa tcgctggtaa atggttgatt attttgcgca actgttgcat gtagtcttgt
     6601 tctatttttt tgctgatttt atttttactt attccaattc ctatccctaa gagtagtaac
     6661 tgtaaaacag tcgcagaata gccttttgta acgaagccta ctgattctac cccggcacct
     6721 aaatcaataa tttgtgcagc ttctaaagca agtggacttt gcacgtcatt tgtgatagca
     6781 acaacaggta acccttgttt ttgtatcatt tttactgctt caacagtaga agcacttttc
     6841 ccgctttgtg acacagcaat cacagtatcg attgaaggag aaagttttcc ataattgaaa
     6901 aaataaaaag gttcttgaat atcgacagta agatcaccat aagattccaa tgctggcttc
     6961 gctgctaaac aagcgttata agatgaaccc gttgctaaga tcagtaaatt cactgttttt
     7021 ttcatatgtt ctcttgtcga aaaatcattc tttttcaaga tcgtacttag tacttccttt
     7081 tcttcataga tataatcttg catcgtaaac attttctctg ctcctttttt aaaaaatccc
     7141 tatccacgaa ccaaaaattc caaagaaagc tagtccgatc aagatcgtta atggtttcac
     7201 ttctttcttc aatagataaa acactatgcc aaatgctcca agacataaga tatttggaac
     7261 gatatcatca aaaatacttt gaacagtcac agcattttct cctgaaccga tttttaaagg
     7321 aatattgatg gtgatcatcg tggcagtcat tgctccaacg accatcagtc caataataga
     7381 cgcgcctaat gtcaaacttt ccatcatacc gtttgcctgg atctttttca aaaaacccgt
     7441 tcctaagcga tatccccaac ctgttgctag atagcgaaac agaatgtgcg gaatattgaa
     7501 aatcaaaatg aacaagatag ggcctaaaat atttccttgc atggctaaag aggtacccac
     7561 acctgtggca atcaatcgca aagttcccca aaagaaagaa tctcctaacc ctgcaagagg
     7621 tcccatcaaa gatgttttga tactatcgat cgcagtcaca tcaaattcag gatcatcctt
     7681 attttcttcc tccattgcag ccgtgattcc taaaatcagt gtaacgatat gtggggtcgt
     7741 gttaaaaaac tctagatgcc gtttcaaagc tgctgccatt tcttctttcg actgatataa
     7801 ctttttcaaa atcggaatca ttgcataaac ataagccata ttcatctgac gttcataatt
     7861 ccaagaaaac tccatttgaa aagaacgcca aaatacgtga tttagctctt ttttcgttat
     7921 tttgctgttt ttgatctcag aattcttcat cttcttctac ctcccctgca gttgtttgaa
     7981 gtggtagttg acggacattc ataatattga ctaccacaac tgctaaaatc gcaccaaaaa
     8041 tagctactcc ggtcacagga atctctaagt aagaagctat agcaaaacct aagaaaaaat
     8101 atggtgcaac ttgtttgttg atcagcaaac gagcaagcat cgcaaaacca agagctggaa
     8161 tcaaccctgt agctactgac aacccctttt gaacgaagtc aggaatcata tttaatagat
     8221 ttccgatcgt attgcttccc accatataag aaaccattac cacaacacca agcatcaagg
     8281 aaagaccgat accggcaagc aagtgcatat gctcgactcc tttataattt ccttcttctg
     8341 cataattgtc tgctttatgg ttcataattg gaatcaaaag ccctaagtaa atatttttca
     8401 atatcaatgt caacgtagca atcggcaaac ctagtaaaag cgcggtttct gtaccggctc
     8461 cagctgtaat agcaaaagcc gtccctaaaa tcccaccggt cacaacatca ggtggaatcg
     8521 aagcacctac tgagaacgat ccgataaatg ctaactctaa agttgcgccc ataatgatcc
     8581 cagtttttac atcacctaac acgattcctg taaacagccc cgtcacaatc ggacgagaaa
     8641 gcaacgatgt ccctagtgca tattctgatt gtgcgacaaa tgcaacaatt cctaataaga
     8701 ctgcttgtac aatcattgag gttcttcctt tcttacaaaa cttctcttac atccactttt
     8761 ttatctgctg gtacttgacg gatttctact tctatttgtt tgtcaattaa tcgtttcaag
     8821 cgttcctcct cttctggtaa aatatttacc gcttttccga tgctgcgagt accaggtttt
     8881 gccttgatcc ctcctaagtt gatggttttg atttctggat acgcttctgc cagcttatat
     8941 gcatcctcga tcgattccac tacgatgaat aacttatatt tatctgtcac cccgcttttc
     9001 aacgcggcaa tcgagtcatc aattgatttg atcactagtt tgactccttg tggcttggct
     9061 aatttgatcg ttgtctttcg tatctcattc gtaggtacat catcattagc aatcaaaata
     9121 cagtctgcgc ctattgtttg tgtccatgaa aaagctactt gtccgtgtaa taaccgatgg
     9181 tcgactcttg tcaatacaat catttttctt cctcctaaaa ttcgtcttct tctattttct
     9241 gattgagccg ctcgttacaa aactggatca ttttttttga atcagttagc acctgctgga
     9301 tcaaaacagt tgtctctact tcagcgtcca accgagatac tagctcaatc aatagtggca
     9361 aattcaatcc ggcaacgaga tagacatgat cccgattgat atattgtaag aattcgttgt
     9421 tgacacttcc gccaaaaaga tccgtcagaa caatgatttc tttatctttg tacctcataa
     9481 aaagctgcct tactgtttcc gctaaatcaa aattctcatc agtatagcaa tcgaatacag
     9541 taatagaatg atttttccca tagatcagct ctaatgaatc taatatccct gaagcaaatt
     9601 ttccatggga agctaagata atttctctat ccactttttc atctcctctt ttcacttaca
     9661 catactaaaa aagcaagttg catgccaaaa ttagtggcaa caacttgctt atgttcaaaa
     9721 ttcttcttct atcgagagaa actctgtatc ttcactcaaa atatcataga tataggcaat
     9781 ctcagaattg gggatcatga cactataatg ctcttcaatg acactaaacg cagatttaat
     9841 agcagataac ccttcttttt gacactgctt ccatttctct aatccttgat aggtttcgat
     9901 tggcatttgt cggatcaatc gttcaatgag acagctcaca tggacataca acgctaattt
     9961 tttgggattg ctgatgcttc gattcaactg cacctctaat tctctcataa aatgatcgat
    10021 ttctcccatc accttctctg tatctagaat agtcacggaa tccagtactt tttccaatga
    10081 aaaattacga atgatgcgct gattgaatat ttccttctct gaagcattca tagtagtgtc
    10141 caaccattca gctagtacag acatcttttc ccccgagatg aggtcttcta atgaaagata
    10201 gtcgatattg gtgatatcag gatctgtggt gccaatcatt cctacgactt cgtatatgga
    10261 aaataatggg tcactgtttt tcttatcttt taattgctga tattcatatg ggatgatttt
    10321 caactgacaa gccgtaggta agcttttttc tagcagttca cttaagtgga ccgccgtacc
    10381 gattccagtg aagcaagtag taatgagtgc tttgggtttg ttttcctctg gatagagcag
    10441 tcgccattct ggctggatct gtcgaacagt ctcttctgct atctcttcta atgatacatt
    10501 tttttgcagg cattccccta ctgtgattgc taaaggtgtc gtcacattat tcaaaatcaa
    10561 aagcggtacg gataactgtt ttttaaaaaa ctgatggatt tctttcagag atcccatgtc
    10621 tactaatatg atcaatccat ttgaaacatc gctgttttcg caataatcaa ggatttctga
    10681 agcaatctgc tgtggtgtga catctagtgg catatcaaat gattcaaata gatcctcttg
    10741 taataaacga tttactacat ttgccatact gctagcagtt gcataaccgt gagcagcaat
    10801 catcgctttt ggcagtcgtt tttcttttga ccatttcgct ttttttagat agatcgtcag
    10861 taaaatccga tccatacttg tgtcttcaat atctaatttg atcttactta attccagaat
    10921 tcgttggaca tagtgataac tagatggata agactgagaa acttgttgtt ctaattcttt
    10981 gattagttgg ataatatcat gttcttccgg taaccatttg atagtgcttc gctgatagag
    11041 atagtaactc aaggcataga cactgtttcc atcgaatttg atttgatagg cagtttccat
    11101 ttgtcgaaag gtctctcgga tagattgtgt ccaataaacc agcagctcgt gtttttcttg
    11161 tctactggtc tcaaacagca aaaaatcaaa taattgaatc acttcttgct ttaattttcc
    11221 ttcgcaagaa tatagcagac agttattttt cttgaaatca attaggattt gctcaaaact
    11281 tttaacgatt cgctgctgtt cgggctgttg cttctccatt aattgctcta aggtctggtc
    11341 ttgcgtaata tagattcctt gctgtgctgt atttttagta ataggctgcg caagtagttc
    11401 tttttgcaaa tgatggatcg tgacatggat ttcaggctgt tcacgctgtt cagcatatgc
    11461 ttttgctgct gaaactttga cgatattttt cagctctcct atgtttccgg ataatttctg
    11521 acttgttaaa agtgacaaag ctggtccact gactgacaaa gggctcccca tttttctttg
    11581 ttcttcgaga aaaaaagagt aaatcagttc tagccgttca ttacgactac gctgattaag
    11641 tgcaggtagt tcgattcgga taggtattct tcgaatgaaa gttgttaaga aatgactagt
    11701 aatctcttca gtcgtagcaa aaaagagacg tgttttgatc cggcgtgaca aattaggttc
    11761 tcccatacga taaatcacac cttgatcaag ataggtgaac agtttttcct gaccttctgg
    11821 tgttaagcga tgtacctcgt ctaaaaacaa gatcccacca tctgctgctt caaaagcccc
    11881 ttttttattt tcttctgcac cagtgtacgc tcccttaaca tgtccaaaca aattgctagt
    11941 caaaagttca ggattatctg catattgtgc acaattaaaa gtgatgaatg gtgcagaatc
    12001 ttctagcaga tcatgaagca gacaatactg atagaccaaa ttaactaaat aacttttacc
    12061 tgtgccactt tcgcctgtaa tcaaaagtgg taatccgcca tctggatagt aaagagctgt
    12121 tttgatttgt tcgatacttt ctttcaaact ggcgtcgtat ccgatcataa aagagaataa
    12181 gtcttttggt tgcgcgaaaa aaggctgttc ctctttgaga tcatcgatag aaaaataaaa
    12241 attcgtgcgt aacttaaaaa attgtttttc aaaagcttct ttgtggaaat aaatcactgg
    12301 tcgagaattg attttgacta gtagttgctc atcatttaac tggttcaaat aatgactgac
    12361 tgtgtttctt tttaccccaa aatgatcagc taacctttgt gctgtaaaga cctcgttcat
    12421 atgttctaaa tcgaaaaagg ctgtctggtt ctctaagtaa cataaaattt ccttcttcaa
    12481 caacttattc acccctcctc catcatagaa aacggattca ttttgtcaat aaaatcttta
    12541 ataaagaatt gaaaaatata tcttattata gacagcagcc tacttatccc ttataatttt
    12601 tattctaaaa aacgtacagt tccttccagt ttttatactg gaatttcaac atatgaaaga
    12661 ataaggaggc tatgactatt caatgaaatc ggataaatat aaaaacagga aacatacttc
    12721 ctggaaaact tttcgagaaa tcatcggatc ttatctcgct gtagttgtat ttttgccttt
    12781 gctttatatg gctatgacag aacaaactcg ttttattggc gtagatacgc aatatatagc
    12841 cgaaacagga tttttattca tctttatctt gatttttgcg ttctataaat ccttccatac
    12901 aaaataagat tcacagattt caactttcct gtctgttttt agctattaca aatccttata
    12961 tgtggtataa caacaattta ttggcataat gaggaaaaac gagttatgat gctttcagag
    13021 agtaaagagg tactgttgtc accatccttt ttattgatta cgtacaccac tcttagtttt
    13081 ttcccattga ttacgaaaac aaggtagaaa cattgatgtt cctaccttgt tttctttttt
    13141 tattttcaga tcaaaatctc aagtggcttt tgacttgatg tcgggaggtt gtcttcgttc
    13201 catcaaacct gatagaatct gcgccaaacc atagttttct ccactattat ttattcctct
    13261 aagatagtac ccacaataaa cgaataaata tttttctcat tttcatactc cttctttgaa
    13321 aatcaattag atttctctca acccactttt ttacaaaaat tacgtagcaa aaaagattgc
    13381 aagaac
//
LOCUS       DAFLVO010000077        12732 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.078, whole genome shotgun sequence.
ACCESSION   DAFLVO010000077 DAFLVO010000000
VERSION     DAFLVO010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.078"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(85..264)
                     /gene="rpmF"
                     /locus_tag="L1U99_002341"
     CDS             complement(85..264)
                     /gene="rpmF"
                     /locus_tag="L1U99_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBN1212865.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(322..891)
                     /locus_tag="L1U99_002342"
     CDS             complement(322..891)
                     /locus_tag="L1U99_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBN1212866.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1077..1979
                     /locus_tag="L1U99_002343"
     CDS             1077..1979
                     /locus_tag="L1U99_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1212867.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="L1U99_002344"
     CDS             complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="L1U99_002344"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBN1212868.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="L1U99_002345"
     CDS             complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="L1U99_002345"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBN1212869.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="L1U99_002346"
     CDS             complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="L1U99_002346"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBN1212870.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8547..8732
                     /locus_tag="L1U99_002347"
     CDS             8547..8732
                     /locus_tag="L1U99_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HBN1212871.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8794..9990)
                     /locus_tag="L1U99_002348"
     CDS             complement(8794..9990)
                     /locus_tag="L1U99_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBN1212872.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10160..11596)
                     /locus_tag="L1U99_002349"
     CDS             complement(10160..11596)
                     /locus_tag="L1U99_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBN1212873.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11889..12698
                     /locus_tag="L1U99_002350"
     CDS             11889..12698
                     /locus_tag="L1U99_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1212874.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3801 a         2672 c         2250 g         4009 t
ORIGIN      
        1 attttttatt taccgactac aaaaaaataa acctcaaggc tccatggtta gccttgaggt
       61 tttacatttt ctaattaaaa tgtattaagc ttcttttgac attacgtcct taccatcata
      121 gtaaccacaa tttgcacata cgtgatggct ttttttcatt tcaccacagt ttggacattc
      181 gtttaaccct ttgattgtca atttgtagtg tgtacgacgt tttgcttttt tagcttttga
      241 tgttcttcta gctggtactg ccattttgct acacctcctt gtaaagtctt gtatctaaat
      301 tagacacaat atattccaat cttacttgtt atcgtcgtct tttgatttag aatcaaaaag
      361 ttcagatagt tttgcaagac gaggatcaat tttattctcg gcttcttcca tttttctgcg
      421 ctggtattct tcttcggaaa caacttccca atcattgcct tttggaagtt ctgttgctgc
      481 ttcctcttct tttgtcaata cccgcattgg aatcgccaat aagatgttgt cttcaatcga
      541 ctctgctaaa ttcaataatg gaccttcaat tagcaaaatc tcatctgcag acatttgttc
      601 atctctactt tggaattgtt cttctgtcat gaatacttcg tctacagaaa aatccatggg
      661 cagttcaaca ggttctagtg aacgtgttga aggaactgtc aaagtcgtct gcacagtgta
      721 atgaacgata tagcctttct tatcaactga gaccaaacct tcgacttcca ctggcgcaac
      781 atcaagtatt aaattgtctc gcttcatgag agcggctttc aagtcgagcg tctcatgaaa
      841 agttaacggt gtctcctggt attttctcaa ttccaataaa gaccatttca tttttcatca
      901 ctcctaagca acaaaagcaa ttatacaggg caaaaagcat gttgtcaatg aaattttctt
      961 gacaccttgc agttcataaa aaaacagaaa aatctttatt agaaagcctc tgtttgctat
     1021 catcctcaga atcatttaca ataatcatta ttccattaaa ggagcggatg atcttcatga
     1081 acacgaaaga tatcgaatac tatgtccaaa tcgtcaaaca aaaaaatttt acgaaagtgg
     1141 ctaattattt ccgtgtgagc caacctacta ttacatatgc attacaacgt cttgaaaaag
     1201 agtttgacac cgtacttatt acaagagatc gatcgcatca cgaattaatc gtcacgcctt
     1261 ctggaaagca gctgtttctc catgcacaaa ccattctcca agagatttct actgcaagag
     1321 ctgaaatcac tcagttgcaa aagaaaaagc ttcgttttgg catgcctcct attatcggca
     1381 atgaatactt tcctaaactg tcaagttact ttatcaagca tgaattgatg aatcaaattg
     1441 agattaccga tggaggctct cgggacttat acgggatgat ccgacaaggg aggatcgatt
     1501 tagctgtatt aggctcaaca cagccaatcg tggatcaata tttagaaaca gagttacttt
     1561 tggacaaacg tttcatgatc gtcgtgccac ctacacatcc tctttccaag caggatactg
     1621 tctctttcaa agatatagca gatgaacagt ttgtactatt gaacgaacat tatgtccacc
     1681 ccgcagcatt cactaagctt tctaaacaaa cacatactca tccaaaagtt gtttatcaaa
     1741 gcaatgactt gacgatttta aagagtatgg tccgagaaaa tgtgggtatc ggttttttgg
     1801 cagagattgc tgtccatcct gaagatcatt tagtttgcct ccctctttca gatgaagttc
     1861 agcctcgctt cttgatttca ttggcaaaac gaacacagca gatcgtcacg cctcttcaag
     1921 aacaagtagt ccaagttatc catgaattcg ttacagcaca aaaaaacagc tcttcgtaaa
     1981 agaagagctg tttttatttt ttattaagct aaattagata gctgttgttt cgccacggta
     2041 aacgatgccg cgacgtgaat caacggtaat caattcacct tctgtaattg ttgttgttgc
     2101 gcctttagca ccaacgatta caggaatatc ttgtgcaatt cctacaactg cagcgtgaga
     2161 agtcaatccg ccttcttcaa cgataacagc agctgctttt tcgattgcag gcatatattc
     2221 tttgtcagtt gatggtacaa ctagaaccat tccgtctttt gcttttttta cagcttcttc
     2281 agcagatgaa gcaataactg catttgcaac gacagatttt tgtccaacgc cttgagcttc
     2341 taataattta gaaccaatca tttgaatttt catcacgtta gttgttccgc gttcaccaac
     2401 tggtacacca gcagtgatca agattaaatc gccttctgat gcgaaaccta attcaacagc
     2461 ttttttagct gctagttcaa acatttcatc agttgttgat ggtttttcag caactgttgg
     2521 gtaaacgccc cagtttaaca tcaaaccacg ttttgtgcgt tcgtcaaaag taacagccaa
     2581 gatatctgca tctggacgat attttgaaat catttttgca gtgtatcctg attcagttgc
     2641 agcaacgatt gttttcacgc ctagattttt tgcagcacga gctacagata aaccgattgt
     2701 ttcagttaca tctgttttat cgaattcgtt caattggaat gtacctaatt ctgataatgc
     2761 attttcagct tcttggtcga tacgtgccat tgttgaaaca gcttcaactg ggtagtcccc
     2821 gtttgcagat tcaccagata gcattgttgc atctgtgcca tcaaatacag cgttagcaac
     2881 gtcagaagct tccgcacgtg ttggacgtgg gttttcttgc attgattcta acatttgtgt
     2941 agcagtgata actgggatac cagcagcatt acattttttg ataatgcgtt tttgaaccat
     3001 tggtactagt tcagctggga tttcaacacc catatctccg cgggcaatca taacaccgtc
     3061 agaaactttg atgatttcgt caatgttgtc gataccttct tgagattcga ttttagggaa
     3121 gatttgaaca tgagtcatgt ctttttcttc taagatttcg cggatatcta gaacgtcttg
     3181 tgctttacgt acaaaacttg cagcgataaa gtcgatatcg ttgtctaaac caaaacgaat
     3241 atcgtcagca tcttttggag taatacctgg caaactaata gaaacgcctg gtgcatttac
     3301 ccctttacgt gatcctagca tacctgcatt tttaacttct acgactaatt cacggtttgc
     3361 ttcgtctttt tcaatgattt gcatatcgat caaaccatca tcaaataaaa tgtgtccgcc
     3421 aacgtgaaca tcgtcaaata atcctgggta agtaaccgcg attttttctt ttgaacctac
     3481 atgttcagga tccatagaga tgcgtgtttg atctcctact tcaaatttga tgtatcctgc
     3541 acgaccaaaa tcagcttctg ttgtgccttg aacagttgta cggatttcag ctccttttgt
     3601 atctaaaaga ataccgacat cttttcctgt ctttttaact gcttcacgga ccatagtcat
     3661 acgtgataat tgttcttcat ggtcaccatg agaaaaatta aagcggaaga catttgcccc
     3721 agattcaatc aattgagaaa taatttctac tgagttactt gctggtccta atgtactaac
     3781 gattttggtt tttttcattt aaaaaactct cccattcaat tttgtttatt taaagctgta
     3841 cacagcttaa atagcttggt ttctttcact cttaaaatga aagtgaatta tttagatcat
     3901 atagtgataa gtctggttta tgtttgttgt tttcaagtgt atcaatgatg tcagacgcaa
     3961 cgatttcgtt gtcatggata ccgacacata atccaccttt tccttcttga agcaattcga
     4021 cagcgtaagc accgaattta cttgccaaca cgcggtcgcg tgcgcttggt gctccaccac
     4081 ggacaacgtg tcccaagata gatacacgtg tatgatagtc accaaattct gaaagtttct
     4141 cagcgaattc atttccgccc attacacctt cagccaagat gatcaagcaa tgtttcttcc
     4201 cgcgatcgcg gccttcttgg atttttttag caactgaagc catatcaaaa tcatgttctg
     4261 ggatgatgat ttcatccgct ccgccagcca cacctgacca taaagcgatg tctcctgcat
     4321 tgcgtcccat tacttcgata acgaatgtac gaacatgaga agtcgctgtg tcacgaatac
     4381 ggtcaattga ttctagtact gtattgattg ctgtatcaaa accgattgtg aaatcagtcc
     4441 caggaatatc attatcgatt gttccaggaa tacctactgc tgggaaaccg cgttttgtca
     4501 aagccattgc gccatgataa gagccgtctc ctccgataac cactagacct tcgattccga
     4561 attttttcaa ttgttcgatt ccttttaatt gaccttcttc agttgcaaat tctggataac
     4621 gtgcagaata caagaatgta ccaccacgtt ggatcttgtc acctacatct gccacatcaa
     4681 gacgacgaat atctccagca actaaaccgg caaaaccata attgatcccg tatacttcca
     4741 gtccttcgta aataccttta cgaacaacgg cacgaacagc tgcattcatt ccaggtgcgt
     4801 ctccgccact ggtcaaaatt ccgatgcgtt tcataataaa cattcacctc attaaaatac
     4861 tttatcctaa gtatgactta ggtttacaac catttttgcg ttaaccacga ctaacattct
     4921 aacattattt ttctcacttg tcttgattta cggataaaaa aatgaaaaaa aatgaaagca
     4981 agtagtattt tttaccgtaa gttatttgaa aaccacatta tcttcgccaa gcagataaat
     5041 aagttgcccc tttatactct tgctgtcatc cacccaataa gcatctgaca gaactacttt
     5101 tcgttgcgtt ttttcgtgat acataactac tggtatatat cctgggtgtt tctgaaaaat
     5161 cacttgtaat tgtttcatta tctcgggatc ttcccgttct tctgtaatac gcaaatagca
     5221 agtttgtgaa ggatactggg cttctaactg gttaggatca gcaaagcttt ctccaattag
     5281 ttgcagttcc tgattatatt tgctgatttc gctccgccct tgaacaaaga tcactcgatc
     5341 aacggcaaac aaattacgat atttacgata aagagttgga aaaactgtga cagaaatttc
     5401 tccactactg tcggttcctt caacaaaggc catcagttct cctttttttg tccgaatttc
     5461 tctaacttcc ttgatcatca ctaataaatt gactggttga ttagggacga tatctgtaat
     5521 cagctgaact tgtttagcta aacgaagacg atcaaaccct tctgcaggat gacctgacaa
     5581 ataaatacct aagtactcct cttccagctt caagcgttct tctagtgtat agtcagcgac
     5641 ttcttcttct tttaatgcca tgattcccag caagtcaaga cttccaccac tgtaaacgat
     5701 attttggatt tttccttcga gatcaagcat caattgtttc ctgttaggag ataattcatc
     5761 aaaaactcct actgctgtca gtgattgcag taactctaat ttcagccaac gcttatcgat
     5821 ccgtatgagg aattgatcca ctgactggaa cgggccattt tgttttcttt cgtttaatat
     5881 atcttctaca aaatcacgcc gaataccttt tatcgctgtc agtccgaatc tgatttcttc
     5941 cttattgacc aactcaaaac tggaattact ttgattaatg gacggcgagg aaagtttgag
     6001 tttattttta cgtgcttctg caatatattc tttcaatttt gatgtgttat gccgaacaga
     6061 attcatcagg ctggtaaaga aagcacctgg atgatgggct tttagatacg ccatttggaa
     6121 tcccacgaat gaataagcaa atgcatgtga ccgattgaat ccatagtttg caaatttttc
     6181 gatatattca tatacggtcg ctgctgtttt ttccgaatat ccctgttgta atgctcctga
     6241 tacaaaatgc gacttttctt catctaatac gtcttttttc tttttactca ctgcccgtcg
     6301 cagaatatct gactgcccta atgtaaatcc agccatagtc gaggcgatct gcatgatttg
     6361 ttcctgatag acgatcactc catatgtgtt tttcaaaatc gggatcagtg aatcatctgg
     6421 gtagcgaatg gcttcttttc ctttcttcct ggcaatgaag gtatctatat tttgcatagg
     6481 gcctggtcga tacaatgcat tgactgcggc aatatcttcg atgttttctg gatctaatct
     6541 tcgtaaaacg ttccggatac cagcagattc aaattgaaat actcctgagg tttcgcctcg
     6601 ttgaaacaag agcagcgttt ttgcatcatt tagcgggatc tcttttaatc ggatctcata
     6661 cccttctact cgcttaacag ctttcaaagt aaaatcaata atcgataagt tgcgtagtcc
     6721 taaaaagtcc attttcaaaa gaccgattgc ttctacctca ttcatcgtat actgggtcag
     6781 aaaagcttca tcagaaccgc gttggagcgg aactagttca agtagattct tatcgctgat
     6841 aactacacct gctgcgtgag tcgaaacatg tcttggcaat ccttctaaaa tcactgcagt
     6901 tttgaataaa agttggtttt tttcgcttgc ctgaactaat tctactaatt gatgcgaagt
     6961 tttataagct tgggtcaatg tgattttcaa ttgattgggt attgcttttg accagcggtt
     7021 tgcttcactt tgcgataaac caaacactct agctgcatct ctaagaacca tttttgctgc
     7081 cattgtgcca aatgttgcga tttgtgccat atgatattgt ccatactttt ctcgaacata
     7141 attcaatact tcttcacgtc gattgtcagg aatatccaaa tcgatatctg gcatcgtaaa
     7201 gcgttcgggg tttaaaaagc gttcgaacag caaatcatat tctaatggat ccacatctgt
     7261 gatttctaac acataggcta ctaatgaacc cgcagcagaa ccacgacctg caccggtaac
     7321 gattttgttt ctatgagcaa aagccattac atcccatacg atcaagaaat aatcatcgaa
     7381 tcccatttga tggatgacag ataactcgta gtccaaacgt tcttggtatt cctttgtata
     7441 gtcagtgatt cggcgttcca cttgcgaata gcataactct cttaaatatt ctccagcttg
     7501 ttttccatta ggaactggat aatgcggaag taatttctga tggaactgga attcaaatga
     7561 aatcgattca gctaaacgct gggcgcctat tacagcttgg gaaagacccg ctttttcgaa
     7621 tcgtttgatc atttcttgtt ctgaaagaag atagacattt gctgttagtg gtaaagatgc
     7681 agataaattt tctaaaggta tttggcttcc ctctttgata tgtttcatca cttcaagtgc
     7741 aaaaagttct tcttgttgta aactagcgat gggatgtaat gcacaaagcg aataattttc
     7801 ttttatcaca tactgatacc attcaggcaa ttgatcaggc gtgttttctg tcaagccgat
     7861 ataaaaattt ctagtaaaaa cattttcaag taaaaactgc caatgaccga aaaagttatc
     7921 ctctttattg aaagcctcag aaacagaatg atttgccgga acaacaaacg ctagatggtc
     7981 ggtttctgtc atttctgcaa gttccaattt ttcttggatc atttttcggc tggaaagttt
     8041 catcagctgc tgataaccta tttcatcttt tgcgtacgca agcaagccat aatttttttc
     8101 ttcataagta taactaagat gtaatccaat gattggctgt actccttctt ctacacaaat
     8161 acgatagaat tcaggtgcac cgtataagac atctttatcc gttatggcta atgaagtgta
     8221 gccttgtttt tttgcttctt gtacatattc tcgaatacgt atcgtacttt gtaaaagaga
     8281 ataagaagta attgtataaa gttgtgggaa aaacatcttg cattccgcct tttttttcgt
     8341 taaaattcac tagcgttaaa aggtttgatc cttttacttt cattaagata gcaggcgctg
     8401 aagttgatta ttccacttca tttgcttgct tgtaatctgt aggaatgagt tctttcgcaa
     8461 gaactcaaat tttattgaga tttggtctcg tttctttaca ttcaaagaaa atctggtaaa
     8521 attaagatag aaaagaggtg ttctttatgc gatatatcgt tacattattc tgggctgtcg
     8581 ttctaggtca agtagtcggt tatattggtg ctgcattaac aagcggaaca tatgatttta
     8641 ctttgacaac aatcatttca ttcattgcgg gtgtcattat ccttttgatt ggtgcagttg
     8701 cgccaagaaa agaaacctct gcccattcgt aaaaaaacag ccaagagctt gagatttctc
     8761 aagctctttt ttattttcta ctcctcacca ccattataat ctgctgcgaa gaactttacg
     8821 aaagttgaat aaagaaagaa gaatatttga cagaacaaac aaacttgtca caataaaaac
     8881 agcactgtaa ttataagcat gcgcgactgt cgatcctagc atgggaccta aaacttgtcc
     8941 aaagttgcta aacatctgat tgtagctata gattcggctg actccttctt gaggcgtaat
     9001 cttactgatc agtgtattga cagaaggcat caaagcgcca gttgaaaagc ctaaaataaa
     9061 gcgaagtata cctaattgga gcggtgtagt gacgaatgcc ataggtaaat aacagcaaaa
     9121 tgataaaatg agtcctccaa ttagaacttt ttgattccca atcttatccc ctagttttcc
     9181 tagtttcggt gaagaaaaga cagcggaaac accagctatc gaaacaatca agccgctgac
     9241 aaaaaggata ttttctgtac ttccgctcaa ttcacgaata tataaggtca aaatagggct
     9301 gatcgtagtg attcctatct gtaaaatcaa ggtcgtaatg aagagaccga tcaaaataga
     9361 gagatgatcc atttttgaaa aaatttcttt ggtgcttatc agatcttttt tctcgattgg
     9421 atggaaatct tctttgacta agaaaatggt caataccgtt gtgatcatca acaaagcccc
     9481 tgtgatcaag aatacatttt ccataccaaa ccactgagcc agtgcaccgc ccattgaagg
     9541 tccgatcaga tttccagcaa tcgctccggt agacaatgtt cctaacgccc atccgctctt
     9601 ttctctaggt gcctgtgaag caatcatcgc tgtggcattt ggaatatatc cagacaaaat
     9661 cccattccaa aaccgcatga tcaaaagcca atacgcgttt ggtacaaaag ccaaagatcc
     9721 cattgttaat gtcatccctg ctgctgcacg gatcatcatg agttttcggc cttttcgatc
     9781 agctagattt ccccagattg gtgcaaccac ggcagatgca aaagcagtca cagagattgc
     9841 tagtcccgaa aacaattcga tttgatcttt tggtgttcct agttgctcaa cataaactgg
     9901 tatgaatggc ataactaaac taatacttgc accagtgaaa aaacagccaa tccacgcaat
     9961 cactaaattt tttctccaat taatctccat ctatcatccc tctttcgtct cttttatcat
    10021 acctattttc gaataaacaa gcaacgatct cgccagtaaa aagagaaaaa tcccgcaaag
    10081 gtcattttat atgtaacgtt ctttttatgt aaaacaaaaa gagatcagaa caaatactgt
    10141 tccaatccct tctctttagt taaattgttg ctagaatgat gaagttgata atgaataaaa
    10201 tatcaacgat ccacaaagca acagaaactt gattgtattt tcctttgatt actttcacaa
    10261 ttgtatagaa aataaatcct gctgcaatcc cataggaaat gctatagcac aatcccataa
    10321 agatcgatgc aaagaaggcc ggtaaagctt cttccatatc tagccatttg atgtctgcaa
    10381 aagaagccat catcattact ccaactaaaa tcaatgctgg cgcagttgct tgatttggta
    10441 caatggcgat cagtggagag aataaactac ttaatgcgaa tagcactgcc actactactg
    10501 aagtcaaacc agtacgtcca ccggccccga tcccagctgc agattcgaca taagttgttg
    10561 tattcgatgt accaaagata gcccccacag aagtagcgat cgcatcggca aatagtgctt
    10621 tatccatttt tgttttgaac ccacgaccat cttccaacgc gatctcgtct tcttttgaga
    10681 aaatacctgt gcggcgtcct gtaccgataa atgttccgat cgtatcgaaa gtatcagata
    10741 aactgaatgc gatgatcgtc atcaatactt gaggaatctt ggaagaatca ctgaataaag
    10801 attgcatgcc ttcagaacca aatgctgcac cgaaagttgt tcctaattct ttaaatgaat
    10861 tacctaacga attcgtttgc caatcaatgg aacttaaatc aacaacaccc ataaaaatac
    10921 caaggactgt ggtcgctacg ataccgataa gaatagcccc acggacattt tttacaacta
    10981 aaatggctgt cagtaccaaa ccaatcacag ccaataagat aggagcgttg tcaaagttgg
    11041 ctaacgcagg gacgattcca ccatttatcg taacatttgt cgcttttccg ccttcaacga
    11101 cagagctcga aatagctgac tggtctgctg aaaaagataa gaatcctgca tttttgattc
    11161 cgacatacgc aacgaaaata ccgatcccgc caccaatcgc atgttgaaga ctttcgggaa
    11221 tcgcccgaat aatcattttt cgaatatttg tgacagtaat aaaaatattg attaatccgc
    11281 aaataaacac cattgccaag gcttgttgcc aagaataacc aagcccaaaa acgaccgtaa
    11341 aagtgaaaaa tgcgttcaat cccataccag gtgcctgagc atatggtaca tttgcgaaca
    11401 atcccattac cagcgtacca ataatcgatg caatgattgt cgctagaaat actgcttgga
    11461 agggcatacc tgatgctgac aaaatcgtcg gatttacgaa taagatataa ctcatggcaa
    11521 agaatgtcgt tactcccgcc attatttcag ttgatacatt tgtattgttt ttctttaaac
    11581 cgaaaaactt ttccataaaa agttccactc cctgaatttt tttctgatgg aaaactataa
    11641 taataaaaaa taagtaaaat agggcaaatc catcgaacaa tttcaaatta tatagacgtt
    11701 tcattcgctt ttcaacgttt ttttaacaaa aaaagcgaaa ataatactta acgttcgtgt
    11761 ttagcttatg tttagctatt tatatagcca taactgtagt ttttgttagg aatagctgat
    11821 tgctcttgtt aattacctaa aatatgctag actaaaacaa atgctagttg aggaaggaag
    11881 gacccttatt gaataaaaaa ttaattgcca tcgatctgga cggaactacc ctcaatcaag
    11941 attcgatgat tacatctaaa acaaaagaga ctctaaaaaa agcaatcaat gccggtcatc
    12001 atgtcagtat tgctacagga cgcccattcc gaatgagcca tcagttttac caacaattag
    12061 aattaacaac accgatggtt aattttaacg gcgcattagt acacatccct aatcagcact
    12121 gggatggtga aagagaaacg ttgatcaatc gtgaaatcgc ttttgaaatc ttatcgcaaa
    12181 aaaagcagct aaatttagat tttatcgctg ctgaaaatcg tgatactttt tttattgaca
    12241 gttttgattt ctttgatgaa aaaatttttg cttcttctcg tccaggagag aagaatttgc
    12301 tttctcctaa aaatttgacg acaaatccta catctttgct tgtccgaaca gacaaacgtt
    12361 ttgcaggagc tgtatctgct gaattaacac gtcaatttgg cagttatgtc gatgttcgga
    12421 catggggtgg acctactgcc atcttagaga ttgtttcaaa aggaatccaa aaagcaaaag
    12481 gcgtgcaaga gattgctaac tacctgtcta tcgatcaaaa agacgtcatt gcctttggtg
    12541 acgagcataa tgatttggaa ttgttggatt atgcaggttg gggagtagct atggctaacg
    12601 gtactgacca actcaaaggc attgcaaatg atgtcactcc tttgagcaat caggaagacg
    12661 gtttagctgt ttatctggaa aaactactta aactataata gagaattaga ttccacaaaa
    12721 aagaggttgt ga
//
LOCUS       DAFLVO010000078        12359 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.079, whole genome shotgun sequence.
ACCESSION   DAFLVO010000078 DAFLVO010000000
VERSION     DAFLVO010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.079"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..465
                     /locus_tag="L1U99_002351"
     CDS             <1..465
                     /locus_tag="L1U99_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HBN1212875.1"
                     /translation="WKMDETYIKIKGKWHYLYRAIDADGLTLDIWLRKKRDTQAAYAF
                     LKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLNNLIEQDHRPVK
                     RRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPD"
     gene            complement(1081..2121)
                     /locus_tag="L1U99_002352"
     CDS             complement(1081..2121)
                     /locus_tag="L1U99_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBN1212876.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(2470..2796)
                     /locus_tag="L1U99_002353"
     CDS             complement(2470..2796)
                     /locus_tag="L1U99_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212877.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2783..3586)
                     /locus_tag="L1U99_002354"
     CDS             complement(2783..3586)
                     /locus_tag="L1U99_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBN1212878.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3939..4229)
                     /locus_tag="L1U99_002355"
     CDS             complement(3939..4229)
                     /locus_tag="L1U99_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBN1212879.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(4365..4544)
                     /locus_tag="L1U99_002356"
     CDS             complement(4365..4544)
                     /locus_tag="L1U99_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212880.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4541..4891)
                     /locus_tag="L1U99_002357"
     CDS             complement(4541..4891)
                     /locus_tag="L1U99_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212881.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4884..6209)
                     /locus_tag="L1U99_002358"
     CDS             complement(4884..6209)
                     /locus_tag="L1U99_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBN1212882.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            6659..7273
                     /locus_tag="L1U99_002359"
     CDS             6659..7273
                     /locus_tag="L1U99_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1212883.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(7438..7680)
                     /locus_tag="L1U99_002360"
                     /pseudo
     CDS             complement(7438..7680)
                     /locus_tag="L1U99_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7884..9203)
                     /locus_tag="L1U99_002361"
     CDS             complement(7884..9203)
                     /locus_tag="L1U99_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HBN1212884.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            complement(9358..9945)
                     /locus_tag="L1U99_002362"
                     /pseudo
     CDS             complement(9358..9945)
                     /locus_tag="L1U99_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10583..10840)
                     /locus_tag="L1U99_002363"
     CDS             complement(10583..10840)
                     /locus_tag="L1U99_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBN1212885.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(10833..11102)
                     /locus_tag="L1U99_002364"
     CDS             complement(10833..11102)
                     /locus_tag="L1U99_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBN1212886.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(11233..11412)
                     /locus_tag="L1U99_002365"
     CDS             complement(11233..11412)
                     /locus_tag="L1U99_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212887.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(11793..>12359)
                     /locus_tag="L1U99_002366"
     CDS             complement(11793..>12359)
                     /locus_tag="L1U99_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212888.1"
                     /translation="EEQLYLESETSQTKVTVSHNRLDVYKRRPETVKKGTELLRLETE
                     KYIMNVYLERSELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATID
                     DYYLVFTRFLTCGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTY
                     TYDDTEEIQNELDRKRMPYQRFERKKRQ"
BASE COUNT         3786 a         2259 c         1893 g         4421 t
ORIGIN      
        1 tggaaaatgg atgaaacgta catcaaaatt aaaggaaaat ggcattattt gtatcgagcc
       61 atcgatgcag atggtttaac cttggatatt tggttacgta aaaaacggga cacacaagca
      121 gcctatgctt ttcttaagcg gttagtgaag cagtttgatg aaccgaaggt tgtagtcaca
      181 gataaagccc cctctattac aagtgccttt aagaaactaa aagaatacgg attttatcaa
      241 gggacagaac atcgtaccat taaatacctg aataatttga ttgaacaaga ccatcgtcca
      301 gtaaagagac gcaataaatt ctatcgaagt ttacgcactg cctcacccac gattaaaggc
      361 atggaagcca tccgaggatt atataagaaa acccgaaaag aaggcactct cttcgggttt
      421 tcggtctgta ctgaaatcaa ggtattattg ggaatcccag attaaatcat agataccgta
      481 agggatttta ttctttattt aaaactttgc aacagaaccg tccgttgcgg gtaataccgt
      541 aacactgaag ggcacgcatt aaggcgtcat cttaatgctt tcctgtagga cactgacgga
      601 gattaccagt ctcccgagcc ttacaggggc ctttcttttt tttgtatttt caattatcac
      661 aatttatcgt ccaaaagtgc agaacgaaaa tcaattcatc acaagcatat cagacaatta
      721 aatttaaaac aactaaaaat atacaaaaaa gtgtaattga atattagcag cactgcctga
      781 aaagaagtaa tatcaggctt ttcagcttgg ggaaataagt gaattacctc tcttcatgaa
      841 ttattataac tcaaaaaagc acatatgcaa acactagttc cctatttttt tgaatgaaaa
      901 ataactaaaa tatctaacga ttatgacttt aaaacctacg tttgcgattg ttttcataaa
      961 cttttaatct aaaaactccg gaataatagc tatttatttg taacatttgt aataaaatta
     1021 aaatcataaa aaagttctaa tttaaaattg atcattttta tagtgatcgc tttttatcaa
     1081 ctactctagc caattttccg tactaactgt tggtaattcg ttaaatgttt ctctttgttc
     1141 gtttgcaagc tttgccgcaa tagctttttc gacaaaccaa ttttttacat aaacgaaaat
     1201 tagattctgc aaattgttta ctttttcagt tttttgtttt tgataagctt tcagcaaagt
     1261 catatataat cctttgtcag catcaattcc ataagattcc agttcttcat aaacaacaac
     1321 tgtttgctct aattcttcag cttttttctt tgcattatga atagtttgga cggttttttg
     1381 agcgtcttcg taagtactag aaaatgtttt tatcaagttt aatacatttt ctggtacaaa
     1441 tgtatttata ctgtcctctt tcatgatgtc gacgaagtta tctagtaaaa cttgattttg
     1501 taactgatca gtttcagtgt ctattatgtg tctattagtg tctatagaat tagaatagaa
     1561 tagattgtct gcgattttcg caattacggt tgagtccttg atatgactgg attttgccgt
     1621 atttgcgatt ttcgcaatta cggtggtatc attgatttct cgcggttttg ccgtatttgc
     1681 gattttcgca attacggtgg tatcagtatt gtcttcctct tccatgattt taaagacgtc
     1741 ttgattcgtt acttctggct tgcctaagta caataaatta ggcatggatt caatcttacc
     1801 gtcacgttta tttactcttc ctctcttctg tttcagaaga cctgcttttt ctaattcctt
     1861 tttgatttta gatactttac cttcgcggca ttgtaacaat ttcattaatt cttcaactgt
     1921 gaatatgaaa aatatattat catcagaatc tacccagtta tttttgactg aataatcaaa
     1981 tcgatcttta agtagcatat aagcaatttt tgcatcattt gatagatcca tgtatttttc
     2041 gttagtaaaa aataccttag gcatttgata atatttttca cgataaattt cttttgattt
     2101 gtaataatta aaatcattca tagccaatcc tctttctgta ggatagcgtt ttgttcaaaa
     2161 ctatgttaca atgaattaaa caaatatatc tatccactat atatttttct actgctgata
     2221 agtcgccaaa ctttgttaaa gcagtagtct ttttttatct ttttttagtt taccttaaaa
     2281 aataaattaa agcaaaccgc tctatttcaa ggtttaagct catagtaact atatcacgat
     2341 attacaataa tattatatca cgatatcgta atattacaat atgaagataa gcgacttatc
     2401 agctttgata ctactgattt ttataaaaaa aatatcacga tattatgata tcgtgatatt
     2461 gaatgtaaat taaattttat tttgtttctt tgctagttta tatccttcaa tcaagtattc
     2521 ttcaggtatg gactttaata gcgcatcttc tataacgtct ggtttacttt tgtctgattc
     2581 agcaatagtc gtccaatatt tgagtgctga cattagaatt ggatttatac gaatgctatc
     2641 tgctgttctt acactacttc cttgatcttt tatgacttta cttatatttt tcttggttaa
     2701 ttcgatttct tctacttctt ttgatttaaa attcttttta tttttatttc ctagtaatct
     2761 acttactgca gcttgactgc gattatcttc tgccatcaaa atcaccaact tcttttaaat
     2821 attcttctgt aaatgcttta tagtcatctt cagctgttga gggtttatta aaattgatta
     2881 gatctgatcc agcagcttgc gcttcgtcaa cggttattgt cctacgaata taagttttga
     2941 aaatttttgc accaatgact ctagaaattt cggttgctgc agacgtcatt tctttagaaa
     3001 tgttataacg cttattatac ttagtaaata gaactcctcg tacttcaagc ttgtcgttcg
     3061 tatattcttt taccgtttca atagtttcac ttaactttat tagtcctttt aatgagaaat
     3121 acgcagcttc aactggaatg ataatttcat cagaaacagt aaatgcgttg actgtaagca
     3181 ttcctaaact tggtggacaa tcaattataa tataatcata gttgtccttg attggttgaa
     3241 gtactctttt aagcctgtgt tcacttccta cttgagtaaa ttccctctct gcagaagaaa
     3301 gggctatgtc ggctggcaaa acatcaattc ctttatagtc cagaatagca tctgtaatgt
     3361 cagcctcccc ttttaatact tcataaattg taggttggtt tgttccatct atatcgaaac
     3421 ctacattatc tgtagcattt ccctgaggat caatgtccac taaaagtaca tttttaccgt
     3481 aaacaaattt caaacatgct gctaaattaa cgctagtcgt agttttagaa actccacctt
     3541 tttgattggc tactgacaat attcttgcca ttaaaatatc ccccattcat cttatattat
     3601 aatataatta tatcataata ttgtgatatt gcaatatcgt atatgcatta tattgtaata
     3661 ttgtgtgatt attttgtttt aaagatatat atcggttcgg atataaagat tattcatatg
     3721 ttattcgaaa ttaaaataat cactttttat tactttaaaa ttttttatta atgataagaa
     3781 atatgttttg cgagcagcaa ctagaataat ttaaacatta ctaaactgtc tatattgtta
     3841 ctaataattc ccttcttata gtgcattttc ttagaaaaaa acaatattac gatatcatga
     3901 tattaagata tcgtaatatt atacaattgt gattgatatt atatatgttt ttttattttt
     3961 ttatcatgtt taatcttgaa ggaatcatat tctttttcta aagacaggag cttttcataa
     4021 acatcagaca tgtttaaact agaggccagg cttaaatcat aaacgaatga agcaggtaat
     4081 gattttattc tacgttgtcg ggttatccag cttgcaaccg ttccttgtgg gtaggcatat
     4141 aactcacaaa attgttctac agtgattcct aaattcttga taatgtaaac attgatcggg
     4201 tgcgagtaaa caaatgtatt gatagacatg gtgcgtaagc ctactttctt ttattattgc
     4261 gtttgcaata atagtttaac acacgcatta ttctagtatc tactcctatt tgtaaaaaca
     4321 aaaaaggatt catagagata actctataga atccgtaaaa taccttatat atataacggg
     4381 aagatataaa acctaaaatt atgataacct gctgcagctt ctacatagaa agagaagcgc
     4441 tcaacaccaa cctcatttat caaacgttgg ccataacccc aaatctcttc tgatagctga
     4501 tcaaaggtta tatactttag ctcatattgc tggataatgt tcattctaat cgactccatt
     4561 tattatcctg gtaaaattcg atatgacgta tttcgtcgta gtgaattttg tcttttccaa
     4621 cgtagatccc cagctcatca ctacctaaga tcttgccaat gatatcttct ggatagtatc
     4681 cttcagcgtt tcgttcttct ttttgaatag atactgatct attttttatg actgcagcgt
     4741 tcaatacttc cgcaatctct tcagtcgtca tttgttcttt tgctaaattt tgactggttc
     4801 gttgttcatt gtcggcatca atttcttcag tatgatcaga taaataaaac cctgcccact
     4861 ttaaacgtcc acgatcattg taatcaatca tttttaattc ccccatttcc gcccgcatga
     4921 ccaccaacaa gtgtgcttct agtaatgctt ctagcgcctt ctaacattga agaagcatgt
     4981 acaatcgacg taaaaccata tttttgccga atcttgtcaa taattttatc taaattttct
     5041 tcgtcaattt gcttttgtgg atcactaaat aaatccagct gaagcgaatc ggtgtacaca
     5101 agcttgctat aggttattcc aacatgcctt acttcttgtc cttcataata cttatcaaac
     5161 aagaaaagac aataattctg caattccttt gtattatctg tgatagggat cttcatctgg
     5221 tgtgaaaacc ctggtctcgt ttctaagatc gacgtgccaa tgtgtaaatg gacacaacct
     5281 gttttacagt tatgctgcct aatgcgtatc gctacttgtt ccgccatttc ttttaccacc
     5341 agctcgattt catttcttct agtataatct cgtggtaaca cttgtgaatt tccatatgat
     5401 ttttcctttg tcggttctgg tgggattgct atatctgttc gatcgatccc attagcatgg
     5461 aagtacagct gtaagccaat cacacctagt ctattcttaa tcgtataagg attccagtta
     5521 gcaagatctc taatgctcat aatccccatc tgattgagtc tttttttcat tcgagagcca
     5581 attccccaaa agtccgtcat ttcaggaata ttccatactt tttcaggaac gttttcgtac
     5641 gtccattccg caacaaatcc ttcattatgc tttgcttcgt tgtctaaggc tagtttagcc
     5701 aaaaggggat tatctccgac acctactgta gcaatcaatc ctagctcttc tttaatattc
     5761 tcctggatca tttgagccag cttctttctc cgttgacttc gtgttccttc agtcgtaaaa
     5821 agattcagtg atcgggtcac ttttaagatt gattcatcga tcgagtaaat cagtagatct
     5881 tcatcagcca catatcttct gaaaatatta tttacctgca tatttcgctt gatatatagg
     5941 ttcatacgtg gtggaacaac gtgtagtgtt ttaggaaatg gttgtggtaa gtcacgtggt
     6001 ctactcacat ttgtaatacc ataccgcttt tttgcttcag gagaagaagc taatatcaat
     6061 cctgaaccag tattatcagc tcgactcata acaacaagtt ctgttgttaa tggatctaaa
     6121 tttctttcta tacattcgac acttgcgtaa aagcttttca tatcgattaa aaagtaatca
     6181 tttactggct cttttgaata atccatcata aataacactc cattctttca cattatacaa
     6241 acatatgttc gatattgtaa agaagaaata gctaaataca taaaaaaaga agcataggta
     6301 tgctatcacc ctgcttcttc ttttgatttg tatgatcaat ttattctatc actttactaa
     6361 ttaatttgaa aatctaataa aaactctcac tctaaaagag tgagagactg caaattagag
     6421 tacggacttt tttggagttc cgttctttaa tattaacaaa tgaataaaat ccttacaaca
     6481 tttgagaata agttatcagt agacacttac aaaaaattct catactattt cctccatcat
     6541 tagtttttgt ctatataagg tttaccctaa atagacactg gtataacatt gaaaaatatg
     6601 gcttcctcgt gtatgattag ggtgtatttt aaatagttgc agaaagtagg taaaagtttt
     6661 gagagttgca tacatacgtg tctcatcgat cgatcaaaat gaacaacgcc agattgaaga
     6721 aatgaaaaaa ttcggtgcag agagaatttt catcgagaaa caatctggcg caacgattac
     6781 tcatcgacct gttttccaag aagcattaga ttacgtccga gatcaagata tttttattgt
     6841 ggaagctatt gatcgacttg gaagaaatta tgacgagatc atcgcttcag tcaattactt
     6901 gaagaagaaa aatgtgaagc tgatcattac tagtttaccg atcatggctg aagcaattgg
     6961 caatcctctc ctggataaat tcattaagga tctgatcatc caaattttgg ccatgatcgc
     7021 tgaacaagaa cggactgaat cgaaacgtcg ccaggcacaa ggaattaaga tcgcaaaagc
     7081 aaacggcgtc tacaaagggc ggcccaaatt atacagtgca gacgcaaaag atccccaacg
     7141 tcgccttgtt tacaaaagca tcgttgaaga tcttaaaaat ggtgttgcga ttgctaagat
     7201 tgctaaagac tacaatgtta cgagacaaac cgtgtataga ataaaaaaag acagcatggt
     7261 caatgacaaa tagttgatca tgctgctttt attatcttct catctttaat ttcctacata
     7321 taattactat ctataaaatt aagtcttact cagaacagat aaagcataaa attccaacaa
     7381 accatttttt acttaactaa ataaagagtc tgttaatata atcttcactt atttacgtta
     7441 atcccctact gtatttgttg gttccttatc tatattttct acaaaatcct tattatcttg
     7501 tgatttagct tcgtataatt ctttgtatgt cgacacattg gttatactaa ttcctatagc
     7561 tagttcttga gactctactt ttctctctag ctcctttgac aaagtgattt gagatttatt
     7621 tggttccgtt ggagtcaatt ctatagattc ttcataaaaa tctctataca taaagctatc
     7681 cctgaataat tcatagcttt aattctttgg cacattttat tgaaatatgt atcactaata
     7741 tccctatcaa ctgattttga ctaaaaagtt acttcaaaca ttcactgttc aaaaatattg
     7801 aggaataaat tttgggtgta aggcattttg agcatacttc tccctggata acttcccagt
     7861 aaaaaaatcg ttagattgtt ggattagatc cattgactgg ctcgcctcag gcgagcaaag
     7921 accctgtaga attcattctg atacacatga taactagata atttgagata gactcgtcta
     7981 cccgtttgga ctaatttccc agcaactttc agaaacttca atcgaataga atgaatggtc
     8041 attccctttt ggacttcttc aaagccaatc gttcttaaga agttgactaa gttgtaagct
     8101 atcaagctga gcatcattcg gacatgattc tccaaaaagc gaggactgtc tgttttgtca
     8161 aagtaaaagc cagctttcgc ttctttaatg aagttctcca ttgtgccacg tttggcatag
     8221 atagaaaaga tggtatcagg agaaacattt tctgatagat tcgtcacgat aaattcatgt
     8281 cgaaagagta gttcgcccgc ttcacgtgtt gagcgtatac acacgcgacg actttgtgac
     8341 caggattgtg cttgataagt ggtcgagaag tactgaactt ctcgttcttc ccacttttga
     8401 ttatcgccat aaagtactga tttctcagct atttgaccta gtctacgatt attcttcagt
     8461 cgaataacat aatgactctt ttttgattca cacgaatcat acacaccagg tgtagcgaac
     8521 ccgctgtctc cacgaaccaa gatgtcagtg tttggtagag agtgattata gtgctctaat
     8581 aaaggtgtga gaaactcctt tacgcctttt gatgtatatt gatttcctga acgtagttca
     8641 gcttttaaga agtcaccagt caatccgtca aaagctacca atggatggta accataggtt
     8701 tggtagtgtg tattataatt cgtttgttct tggtgaccaa atgtatctga atgggtcgaa
     8761 tctaaatcaa tgattaattc cgtatcatta cggatgaggc gtgctttatc gataagttct
     8821 tggttcaaag cttgaagttc atggatattc tcctcagata gtcgatctaa aaatcgggaa
     8881 agtgaagatt gagaagcgag ttctttccta tctaaaacag ctttaaacac aggatcttgt
     8941 ctcaggagat tagctgcaga atcagctgag taaccagcaa ttaattgcat aatgaactgc
     9001 tcaagtatgg ataagttgtc atgagtaaaa tacgctcgtt cgtcttcaat gtgaatgtgt
     9061 tgcttagcca gttcagaaaa accaaagatg ttcatcagct ctttcactag gacgagaccc
     9121 gaatcactcg ataattgacc acctgtatga gaaatagtga tatttgaatt gaattttact
     9181 tggtttttgt gtaagctagt catgaaaaga actcctttct tttggttggt ttagtcactt
     9241 taaccatagc agaaaggggt tcttttttca tcacttaacg ggtgaagatg aaaaagtaat
     9301 tgtaagctgc cgtgaggcag tttcacatgg ttttaattaa aagtatgaat tattcaggct
     9361 atcattaatt ttataaaaaa aattaaatgt ttttagcact gccatataac attcaaaaca
     9421 ttcttctata gttggtttac ttccttgagg agaatgaacc aatttattac gtttttctat
     9481 gaaattttta atttcctttc ttatttcttt cggaaactca atattaaagt accctttaaa
     9541 catgctccct aataatttgt ctacaggggg agattgtaaa ttctcaaata ttagagttaa
     9601 atcaggtttc tcttgttgat aaaattcctt tacccctatt tcacaggctg taattatcga
     9661 aataaaccta tctctagtat ttgatatatt tttacttctt ttaaggagta taagagaaaa
     9721 ggggatactt tcgtgtccat gcatgtaatt aactaattgt tgagcttcag aagttatatc
     9781 tctaattata tagttaacgg aattaggaag tgtctttaac tctaatgaaa tttctatcca
     9841 attactatct tctaatctgt atatgctcga agtataattt gattcgtcag caagcatcgc
     9901 tacatcccaa acactgatca taaaatcttt taaacgttca atcatttcag caatattgct
     9961 aaaatcagct aatttttctt tagaataaaa aaaaacattt atatcagaat caataaattc
    10021 tattttttta ttactatatc gtcatcatta tcttgaccat ttatgtttat tgttccctga
    10081 gtggggagta cttctttcaa attcaagtta aatttatatt ccattacttc tcctccaata
    10141 tataaaaatt acttaactgt atccaaattt aatatgtaaa taaatcatta atttttagct
    10201 aaattctatg agaagtttat ttttgttgtt tttgctaatt aactaaaact agtacaaaaa
    10261 atttaaaata gattattaaa cctattgctt attctattca gtcatatata taagcgtcat
    10321 cctttagtaa ctaacatccc acactacaat agtattataa catatctatt caacttcaaa
    10381 ttgttgaaat ttaagccatt tatatttact tttcctcaac tttagaaatg attttactaa
    10441 ccttatatcc gtaatacgcg taacaaacac attcattaat aacaatcaac actaagctat
    10501 attagctttt taaatgacta gggtaaataa aataaggatc aaaaactttt aagtttctga
    10561 ccctttcctt acttccgatt ggttaatagt gatcttttgc agaataaata aatatcgttt
    10621 cattttcaac tctatatatc agtctatgtt catctgtaat tcttctggac cattttccag
    10681 ataaatcatg ctttaatggc tcaggttttc ctaatccagc aaagggggaa cgatcgatat
    10741 cttttattaa cttgttaatc ttttttatat tgcttttgtt tccttgctca tgccaataaa
    10801 gataatcatc ccaagcatca tcagaccaag ccttaatcat cagattcaac ctcgattaag
    10861 tcatgtgttt taaatgcacc tttggagaat tgttcatctc ctcgacgaat tttttccatg
    10921 acgtaattat tagaaagtgt tctcaacgtt tcttgcatag aatcataatc tctttttgat
    10981 aatacaacaa ctgtatcttc tacatcttta cttgttacaa taagtgtttc agcatcctca
    11041 ttaacttgtt tcatataact acgtaaattt tggcggaaat ttgaataagc tactgcttcc
    11101 attcctttca ccccttattt atttctataa aacaattgta cattatattg tacaattaag
    11161 caaatgatta atattctaac ttcttataat taaaagtgct atcactttta gtttttagga
    11221 taaaaagtga cgtcactttt tgagtgctgg tacctcaaat cctgcttttt cttgggcaat
    11281 caataaatct aacgcaatac acataatcct ggattcactt ttgccgtact tctgctttag
    11341 ttgctgcaat tctttttgtc tcttttcatc caacgtaacg ggtaaccgtt tatttcctat
    11401 tgcaattggc attagtactc tctcctttca tcgaaataac cctatgaaaa atatggctgc
    11461 aatcatcttg aatagtagac tcacaagggc taatacaaag cgccaaaaga tcaaacaaaa
    11521 taccagtatt gccaaaaata ctacgaagtt taaatgcaca gctgcagcat ggcgcataag
    11581 tatttcgcca acaaatagga ctaacaatag aggaatgatt ttattcatat ggatctcctt
    11641 ctttctctta ggttatcggg tgttgcccgc ttatttcgca ccacctaagc ggcgggggcg
    11701 gttggagcga ttggtgcgaa ataagaacca ttcccttagt tactaggttt tttgtcctta
    11761 tttcacacat tctcactttt cggtataaat gattattgcc tttttttcct ttcaaatcgt
    11821 tgatatggca ttcgtttacg gtcaagttca ttttggattt cttctgtatc gtcgtaagta
    11881 taggtgtcta aaaaatcagt taaagtcgtg taccagtcgt cgcctgggtt atctacttct
    11941 tctacatatt ccctcaaaaa tgcttcgggt acagcgagtt cataatccat tcccattaac
    12001 acgatagatt ccgttccaca cgtcaaaaat ctagtaaata caaggtaata atcgtctatc
    12061 gtcgcatctt tgctgtttag ctcttccatt tcttcttcca ttaattccat gctctcaaaa
    12121 attgaataat attctgattc tgagtaatag tgtttcctgc aaatcgtgta gctgacaaag
    12181 ttttcgacca gctcactcct ttctaggtaa acattcatga tgtatttttc tgtttctagt
    12241 cgtagaagct ccgttccttt ttttaccgtt tcaggacgac gtttatacac gtctaaacga
    12301 ttatggctga ctgtgacctt cgtttgactc gtttcacttt ccaaatacaa ttgttcttc
//
LOCUS       DAFLVO010000079        12202 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.080, whole genome shotgun sequence.
ACCESSION   DAFLVO010000079 DAFLVO010000000
VERSION     DAFLVO010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12202
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.080"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(164..328)
                     /locus_tag="L1U99_002367"
     CDS             complement(164..328)
                     /locus_tag="L1U99_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212889.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            623..1951
                     /locus_tag="L1U99_002368"
     CDS             623..1951
                     /locus_tag="L1U99_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HBN1212890.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2153..2986
                     /locus_tag="L1U99_002369"
     CDS             2153..2986
                     /locus_tag="L1U99_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HBN1212891.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            3002..3739
                     /locus_tag="L1U99_002370"
     CDS             3002..3739
                     /locus_tag="L1U99_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HBN1212892.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(3894..4862)
                     /locus_tag="L1U99_002371"
     CDS             complement(3894..4862)
                     /locus_tag="L1U99_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBN1212893.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            5094..5927
                     /locus_tag="L1U99_002372"
     CDS             5094..5927
                     /locus_tag="L1U99_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HBN1212894.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            5961..6800
                     /locus_tag="L1U99_002373"
     CDS             5961..6800
                     /locus_tag="L1U99_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1212895.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            6826..7386
                     /locus_tag="L1U99_002374"
     CDS             6826..7386
                     /locus_tag="L1U99_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBN1212896.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            7585..9306
                     /locus_tag="L1U99_002375"
     CDS             7585..9306
                     /locus_tag="L1U99_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HBN1212897.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            9471..10613
                     /locus_tag="L1U99_002376"
     CDS             9471..10613
                     /locus_tag="L1U99_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBN1212898.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            10629..11840
                     /gene="thiI"
                     /locus_tag="L1U99_002377"
     CDS             10629..11840
                     /gene="thiI"
                     /locus_tag="L1U99_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBN1212899.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
BASE COUNT         4156 a         2049 c         2535 g         3462 t
ORIGIN      
        1 cgtaggttcg agtcctactg ccggagtaaa taaagcttat gcaaagaaaa agaaatccaa
       61 tcacttgggt ttctttttct tttattatta tgatgaatca agctttctgt ttttgtcacg
      121 tatgttgtaa tctttacgaa agagtagagt tggctactca taatcaacca tacttcccat
      181 catcgctaaa tacgaaataa atcagcattc ctacaccaat caaagcacaa gctgcaccaa
      241 gaaaagggat gacattccca aagttatctg tattcataag tatgccacca cccacaaaca
      301 aaaagccgcc agcaatcagg tttttcattt tattcatctc ctttcttacg ttatagtatt
      361 tccttctttc aatgagtatt ttgaaagcta tcttattgta tgatgttctt ctaggcctct
      421 tctttattat acaggccatt ttcgttatct catagaaata ttccttttta tctgaaaact
      481 attgtatacc gtatgacatt tttcttcatg aagttgtaag tatattctca ttcaaatgaa
      541 aatttcatca tagaagagat tgtatttcta aattcttaag agtaaaatac gaagtataac
      601 ttggatttgg aaggatgatt ggatgaaagc tattacgcct gatatgacaa caaaatttaa
      661 caaacagttt caagcaaata tcaaacagca ggcattgcag cgggcagttg tgaagaacgg
      721 aattactgct tctgctgaaa atgtttcagc acatgtggag aatacaccgg tattttctat
      781 agatttggct acggggaaag tggctaatca aatgcaatcg gggcgttgct ggatgtttgc
      841 tgcactgaac acattccgtc ataagatgct gaatcaattc catttaaaag agtttgaatt
      901 atcacaaaat tacacttttt tctgggataa atatgaaaag gcaaattatt tctatgaaaa
      961 catcattgca acaggaaaag aggcaatcga tagccggaaa gtagctttct tactcgctac
     1021 tcctcaacaa gatggcggcc aatgggatat gatcgtttca ttattccaaa aatatggcgt
     1081 tgtgcctaaa tcggtgatgc cggaaagtgc gaatagttca aattctcgag atttgaataa
     1141 ctacttgaac aaattactgc gtaaagatgc agtagtgtta cggaaaatgg ttgctcaagg
     1201 agaaacatta gacgctattg aagaaaagaa agaagaaatg ctagaaagca tttataactt
     1261 cttagctatc tcattaggaa cacctccaaa agaattcgat tttgagtacc gcgatgaaga
     1321 aaagaactat catcttgacc gaggactgac accacaaatt ttttatgata aatacatcgg
     1381 tgtaaaatta gatgattatg ttagcgtgat caatgcacca acaaaagaca aaccattcaa
     1441 tcgttcttat acagtagaga tgctaggaaa tgtcgttggc gggaaagaag tcaaatatct
     1501 gaatgttgat atggaaactt tcaaaaaatt agcgattgct cagcttgaag aaggagaatc
     1561 tgtttggttt ggttgtgatg taggtcaatc ttctactaga actagtggca tcatggcctt
     1621 agatgcttat tcaatggatg atctatttga tacggatttt acaatgacta aagctgaacg
     1681 tttagatttt ggagaaagtc tgatgaccca tgcgatggta ttgaccggtg ttgacttagt
     1741 agacgggcaa tcaacaaaat ggaaagtcga aaatagctgg ggcgaaaaag ttggaaagaa
     1801 tggcttcttt gttatgagtg atgcctggat ggacgaatat acgtaccaaa tcgttgtaag
     1861 aaaagattta ttgacgaaag agcaattaaa tgcgttcaat gaagaaccaa ttgttctatc
     1921 tccgtgggat ccaatgggtg ctttagcata gacgagtatt tcaatgaaga gtatgtagta
     1981 aagataaaaa gagctggctt aagccagctc tttttatctt taaagtccat tccctgtttt
     2041 ttatggtccc tgtgctataa ttctaaataa aggataagga ttggaaataa tccttttatc
     2101 attaaaaata tgatgacgaa gtagaataaa attgggagta ggggggaaag tcatggatat
     2161 ccaaactgtt ttatctgatc tgaaattaaa tggtaaagtg attccagttg ttggtggcga
     2221 tgttaatcag acctatcgta taaaaaccga acatcgtgct tattttttaa aaatccatcc
     2281 gaatgtaaaa aaaggatttt ttgaagcaga agtagacgga ttaaaagaac tgtcagcatt
     2341 cgtacgtgta ccggatacgt atatgctagg tgaaacaagt gaaggcgctt atttgttaat
     2401 ggaatggatc gagccgggaa aaggggatca acgagatctt gctgcagctt tagctaatct
     2461 ccatcagcaa acagcgccac aatttggttt tcgtaaagat aactatttgg gtacacttgt
     2521 tcagaaaaat tcttttgaag aagattggtg gacttttttc tttaaagatc ggcttgaatc
     2581 ccagatttct ttggcagaag aaacgaatcg atggaatgta cagcgtcaag aaaagtatct
     2641 gcgatttaaa gaacgtgtat tgaaatcggt tgaaccaaaa aagatcactc cacgcctctt
     2701 gcacggagac ctgtggagtg gtaatgtgtt ctttgaccag caagggcatc cagtttttgt
     2761 cgacccagct gtttcttatg ggaatcggga acaagatatt gcaatgagcc agttattcgg
     2821 tggtttccga ccggaatttt tagatgctta tcaaactata tttccattag aaaagggatg
     2881 gaaagaccga ctgccgattt accagttata ttatcttttg gcacatttga atatgtttgg
     2941 agaaagttac ggttcccaag tagatcaatt actagaaaat ttttaagagg agggcgtgtt
     3001 tttggcaaaa aaatatacca aaaagcatga agtttcatat tatgagtgtg acatcaacca
     3061 aacgatgaca tttccttcga tgttaggagt agttatcaaa acgtctgaag atcaaagcga
     3121 ccagttggga agaggcagtg aattcgtcaa tagctttgga cttacttggg tcatcacgaa
     3181 ttattccatg gagattaatc gtctccctag agtcggtgaa gtaatctcag taacgactca
     3241 agccatggag tacaataagt ttttctgtta tcggaacttc tggatccatg atgaagatgg
     3301 gaaagaatta gtcaaaatag aatctgtttt cgtattgatg gattttgtga atcgaaaaat
     3361 gagcagtgtt aatgaagaga tcattgctcc ttttgagagt gagaagatca agaaaatcaa
     3421 gcgtcaggaa aaaattgaaa agattgattc gggcttcatg ttgccatatc gtgttcgttt
     3481 ttatgatatc gatagtaatc agcatgttaa taatgcgatg tattttaatt ggatcattga
     3541 cgtattagga tatgactttt tgactacgca tgttccagaa aaagtaatta ttcgatttga
     3601 taaagaagta gagtacggga atgagatcga aagccatttt gaacaaatcc ctatcgaaaa
     3661 tggtgtcaaa acaaaacatg aaatccgaat gcaagaacag ctgtattgtg aagcaaatat
     3721 tatatggaaa aataaataaa aaagaggttg tgacagaagg gggcaacttc aagaaataag
     3781 aagaaattta cgaaaattgt ttctcaaatt tttgtaaatt ttcgacttag ttttcgaaga
     3841 agctattttt gtcacagcct ctctttttaa gtttagctat tagataatga tgtttagttt
     3901 tggataaacg aaatcaattc ttcacccgac aaaccatagt ttacagcaat caatagtttt
     3961 aaacgtgctt tttgactatt aatactgtta cagaaaataa tccccatttt ttctagttct
     4021 tttcccccgc cttcataatc ataaacaggc tctgcgattc cattgaaaca acgagaaaca
     4081 agtactacag ggattttttg gacaagaagc ttttccaaag cagctaaggc ttgtggaggg
     4141 agattccccg cacctaaagc ttcgattacc aaaccgtcta ctttcgtatg ggcgatggct
     4201 tccaataagt ccccttgcat cccagcatat gctttaacga tcgggatagt cccatctaca
     4261 gcggaaatgt ccagtcgctt tgtttctaaa agttcctgca agaataaaat tcgattctta
     4321 gttactaagc cgatgggacc caatgtaggt gttcggaaag tagcaacatt tgtggtatgg
     4381 gtctttgtca cgtagcgtgc agaatggatc tcatcgttca tgaccaccaa aaccccctta
     4441 tctagcgctt cttcacaact tgcgacacga atcgcacttt caaaattata aaggccgtca
     4501 cttccaagtt cattacttga acgcattgcc ccagtcaaaa caattggtaa tttgttgcca
     4561 atcgttgtat caagaaaaaa agcagtttct tctaatgtat ctgtaccgtg tgtgatcacc
     4621 actccggata tacctgatgc ataagcggac aagatacgtt cttttaatac caacatgtga
     4681 gaaggcatga tgtgtggtga gggaagattg aagatatctt caactaataa ttctacatgc
     4741 ttggggattg tgatttctgc atctaataat gggtttgcca catcaggact aacaccgccc
     4801 gtgagcatgt tttctttcat ggcgatcgtt ccgccggtgt gtagtacaag tatttttttc
     4861 attttacaga cttccttacg aataattttg catagccgtt aaatcttatt gtatactata
     4921 taaaagagtt ttgctatcag tgaagaataa cgaatagcct aacttatcat aaaaaagctg
     4981 accttattaa aatggaaaag actcaacctt gacctcctaa tacaatggag tatctggttg
     5041 agtttctttt acaagaaagc agccaaggaa atcaatcacg aaggtggccg gaaatgatca
     5101 gaatcggatt aacatcgttt aaagaacatg acaaattaac tggtaaaaag aataacactc
     5161 tttatgaata tgcagggttt ctacccttag tggaattaga tactgcctat tatggaattc
     5221 cccgaaagtc ctcagttgag aattggataa gtgaagtacc tgaatcattt cgctttgtag
     5281 tcaaagtcta tcaaggaatc agcggtcaag gagactggaa gccttattat cagaccgaag
     5341 aagagatgat tgcgcatttt ttagatgtta tgtcgccaat ggtagatgct ggaaagatgt
     5401 tttgcttttt agtccaattc ccctcatcat tcaaatgtac gaaagaaaat gtccagtact
     5461 tgcgcaaact tagaaagtgg tttgagggtt atcctgtttc tatagaattg cgggattatt
     5521 cttggtacag cgatgaattt cttgaacgta caagaaactt tatgtctaga gccgcttttt
     5581 ctttagccat catcgatgag ccacagttgc tgaatacaac gattcctttt gatccatttg
     5641 tcaccaatcc gaactttgct ctttttcgat tccatggtag gaatgcgcaa ggatggcaag
     5701 caaatgataa agagtggcgt aaaaaaagaa cgttatatcg ttattcagaa aaagaactgc
     5761 aagaactagc acatgaagtc aaagtagttg attctaagac aaaagaggta ggtgtgattt
     5821 ttaataataa ttctggtggt gatgcggctg aaaatgcatt agcactgcaa aaaatattaa
     5881 atatcaagcc agatggactc aatccaaccc aaatggatct gttttaaggg cttattttat
     5941 tcaagaaagg ggcgaagtct atgatcaaag ctattttttt tgatattgac ggaacattgg
     6001 tcaccaatcg ttcaaaagcg ttggaatcaa caaaacaagc aattgaatat gctcggaaaa
     6061 acggcatttt atgcggtgta gcaacggggc gcagcccagt aaagatcaaa gaaatcattg
     6121 atgaattgga attagatatg tatgtcgtgt ataatggtca actggttttt actgcagatc
     6181 gcacgattat cgaccaccct tttgaacaaa aagtattgga acatattgtt gaatttgcag
     6241 atgagaacca tcgacaaatc gtttttggtg cgagaaatcg gttagatgga tcaacgacga
     6301 tgctattagg acaatcgatt tttatcaagc gactagtcag ctttttaccg cgtaaattcc
     6361 cggtacgtct gatgaaaaaa atcctccagg tttttagccc tcaccgacaa aaggatcgtt
     6421 atgaaacgtt agagatatta aaagaaccaa tttatcaatg tatattgctc agtccggagt
     6481 cagaacagaa aaagttagaa catcgctttc ccgagtgtac gtttcagcgt tcaaatacgt
     6541 atactgtaga tatcatccca aaaggtggtt caaaattact aggcatccaa gctttcgcaa
     6601 atgctgtcga aattgaaatg gaagaaatta tggcattcgg cgatcattac aatgatatcg
     6661 agatgctgaa aggtgtagga attggagtgg ccatggggaa tgctcagatc gaagtaaaac
     6721 atgctgcaga ctttgtgact caatcaaatg aagaagatgg gatatacgaa ggactgaaac
     6781 acttcggtct gatttattag tcaatgaaag aaggaaaaaa tcagtatgga agcagagaca
     6841 ccttttcaaa aagtagaaac attccacaaa acttttgatc caagaagacc agagataccc
     6901 acggctttta cagaaaatga agctcataca cgtgctgcgt tcaaaataga agaacttgtt
     6961 gaatttgttg cagctacttc acctaataaa gaacaactgc atgaagctgt tatgctgctg
     7021 cacgaagcat tagataaagc agaagaaaaa atacttggta aaacacagtg gggaagtgat
     7081 ccgctggttg aacaagtaga tgcactgaca gatatccttt actttactta tggttctttt
     7141 tcattactag gaatagtgcc tgatcgaata ttcgaaatcg tccatcaggc aaatatgggg
     7201 aaattatttc cagatggaaa acctcattat gaccctgtaa caaataaagt gttgaaacct
     7261 gaaaactggc agatggaata tgctccagaa cctaaaatcg cggcagaaat ccaacgtcag
     7321 attcaagaag cgattgctaa gaagaaatcc gctgatatag gcatgtgcac aaatgaaaaa
     7381 gagtgatcag agtttcacta tttttgttat ctttatacga tggaaaaaca aaagattttc
     7441 gtttaagtta gtgaatgcat gaaaatagta tgctataatc tagaatagat gtcttttgca
     7501 cgagagacgt attatttgga tttatgccaa gcagaacgcc atctgttgca taaaagatgc
     7561 atactgaaaa cggaggaacc ataaatggga aataatgtta tcatcggaat cgtcattgca
     7621 atcattatag tcgccattgt cgtctttttg gttagttact tgatgaagaa aaaaaaccaa
     7681 gatcgattgg atgccttaga aaaacgcaag gaagaattat ttgacttgcc agtgattgaa
     7741 gaagtcgatg atgttaaaaa aatgcatctg gttgggcaaa gccaaaatac ctttcgtgaa
     7801 tggagtcaaa aatggaatga catatctact tcctcgttcg ctgaactaga aagtcaaatt
     7861 ttcgaagtgg aaaacctcaa tgaaagtttt cggttcttaa aaggaaaaaa agcagttgtt
     7921 gaagcagaag ctacaatgga ccaaatggag aaacaagtga cggaaatccg tgaaggtcta
     7981 aaggaattgc gggaaacgga agaacgcaac tcactagctg ttcagcaggc acttgacgtc
     8041 tatgaagaac tgaaagaaaa agtcagagaa gacgagcatg aatacggacc agctcttttt
     8101 gaattgcaaa aacagatcaa agtgatcgaa aaagaattta cgcagtttgt gactttaaac
     8161 acttctggag accctgttga agcccgcgag gttttggata aagcagaaaa acatacgtat
     8221 gaagtggaag ctctgatgaa aaaaattcca ccgctgtatg aggagctcca taccactttc
     8281 cctgaacaac ttgaagaaat cagtgatact tacgagaaat tgatggaaga acaatatgta
     8341 ttcccagaag aagatcttgc tgaagatatc gcaaaagtaa gtcgaagaat tgaaaattca
     8401 ttagccaatc ttgaaaaaac agaagttgaa acggtcgaat ttgaaaaccg tgaaacagct
     8461 gatttgattg attcgttata tgatatctta gaacgggaaa tggaagctca gagatatgta
     8521 aaaactaacc aatcaacgat tgcagagtat atcaaacata caacaaagaa taaccgtcaa
     8581 ttattgattg agctggatca cacatctcaa agctatacat tgaaccacaa tgaaattggc
     8641 cgtgtacgag gtttccaaac cgaagtggaa gaaatggaac gtcaaaatga acagatgatt
     8701 ccacagatcc gtcaacacga aattccttat tcagaagtgc gcacgttcta taaaacagtc
     8761 ttcaaagtct tagaagatat cgaaaagcaa caagtagaga tcgacgactc attacatgaa
     8821 ttgagaaaag gcgaaaaaga agcgcaagaa aagatcgata cattcgaatt caaattgcgc
     8881 agtttgaaac gttttgtaga aaaacaacgt ttgcctggct tgccgaatga ttacctagaa
     8941 ttcttttttg ttgctactga ccgtattgaa gaactaagtg ttgtcttgaa taaaattcga
     9001 gtaaacatgg aagaggtcaa tcgtttagtt gctctatgtg aagaagatct agaattatta
     9061 gataagaaga cacatgattt agtagatgca gcagcattaa cggagcaaat gctccaatat
     9121 gcaaatcgtt atcgtcatac acacgaagaa gtgagagaag caattgataa aagctactat
     9181 ttattcaata aagaatatca ctatcaagaa gcattagacg aaatcggtac agcattagag
     9241 cgagtagaac ctggtgcttt caaacgcatc gaagattttt attttaatca tccagactta
     9301 gtataaagca aaaaagttag taaaccagca agagcaagac ggattattgt cttgttcttg
     9361 tctttttttg tatatttgaa aattgaaaca agtgaaaatt tcacctgctc ttgaaagcac
     9421 cttggacaac cgttataata gaaaagaatt tcaaaaaaga ggggtttctt atgatatatt
     9481 ttgataacag tgcaacaacc ccaatctttc cgcaaagctt agatgcatat gtaaaaacca
     9541 gtcagcggat tattgggaat ccatcaagct tgcatgattt aggcaatcaa gctaaccggt
     9601 tgttgcagca agcaagaaag cagatcgctg atttgatcca tgtagaacca gaagaaatct
     9661 attttacttc aggcggaaca gaaggagata actgggtatt aaaaggaacg atgatcgaaa
     9721 aaagagaata tgggaatcat atgatcattt caggagtcga acatccggcc gtcagcgaga
     9781 cagcagaaca attaaaagaa ttaggaatcg aagtaagtat cgccccagtg gataaacgcg
     9841 gatttgtacg tgtcgacgaa ttgaaagaat taataagaaa agagacagta ttagtctctg
     9901 ttatggctgt gaataatgaa gtaggatcga ttcagcccat ccaggaaatc agtgatcttt
     9961 tggatgattt tcctaaaatt catttccatg tagatgctgt tcaggcgatt ggaaaagtac
    10021 cattctcgca atggttgaca gaaagagttg attttgcaac attttcagct cataaattcc
    10081 atggcccacg gggaactggt ttcatttatt ggaaaaaggg tcgtcgttta gcaccattac
    10141 tgacaggtgg agggcaagaa agaaatcagc gaagtgggac agaaaatgtt ccaggtattg
    10201 tggctatggt taaagcttta cgtttatcat tagagataaa ggaacaaaaa cctgagcaga
    10261 cacaacgctt aaaagtagct ctaatcaatg cgttgaagac gtatgagaaa gtgacgattt
    10321 tttcagaagg aactgactat gcaccgcata ttttatgttt tgctctaaaa ggaattcgcg
    10381 gcgaagttct cgtccatgcc ttagaagaaa aacaaatatt tgtttctact actagtgcct
    10441 gctcctcacg taaacatatg gcaagcagta cattgcacgc aatgcatgta ccaaatgatc
    10501 tggctacatc tgctgttcga atcagcttag atgaaaacaa ttcgcttgca gaagtcgagc
    10561 aatttatgat tattttcaag cagctttata agaaattttc tgcaatcaat taaaagagga
    10621 gtgttcttgt gaaatacagt gaaattatgg tccgttatgg ggaactttcg acaaaaggaa
    10681 agaatcgaaa aagctttatc atgcaactag cacaaaatgt cagacaagct ttgaaagact
    10741 ttccagaaat caaaatccat gctgatcggg accggatgca tcttttattg aatggcgcag
    10801 acgggcagct agttattcca aaactagcaa aaatatttgg gatccaaaat ttctctccaa
    10861 gtattcgtgt agaaaaagat gtcgaagttt tgaaacaagc tgttcaagac atcatgaaag
    10921 aaatttatac tgggaaagaa acatttaaaa ttatcgctaa aagaagcgat caccaatttg
    10981 aattgacaag taatgaattg aatcaaacat taggtaatgc tgtttttgat attttcccgc
    11041 atatccaagt tcaaatgcgt caaccagata ttccattacg tgtagagatt cggcgtgatg
    11101 gcgcttatct atcgtatgaa acgatcaagg gagctggagg attgcccgta ggaacaagcg
    11161 gaaaaggaat gcttatgctt tctgggggga ttgattctcc tgtagcaggg tactttgcca
    11221 tgaagcgggg agtggaaatt gaagctgttc attttgctag tccgccgtat acaagtgaac
    11281 aagcactgca aaaagcaaaa gatctaacag ccaaactagc accttatgtg ggaacgatcc
    11341 attttatcga agtgccattt accgagattc aagaagaaat caaaaagtca gtgccacaag
    11401 gatattggat gacaattact cgtcgaatga tgttgcgttt gaccgatgaa attcgccgta
    11461 ttcgtcatgg tttagtcatt ttgaatggtg aatcattagg tcaagtggct tcacaaactt
    11521 tgcaaagtat ggtggctatc aatgaagtaa cgaatacgcc aatcattcgg cctgtagcga
    11581 caatggataa acttgaaatc attgaagtag cagaacagat cgatacattt aatctttcta
    11641 tccagccttt tgaagattgc tgtacgattt ttgctcctcc acagccaaaa acacgccctc
    11701 aactggaaaa ggtccatcaa tatgaagagc gtttagcaat agatgaaatg atccaacgag
    11761 cactagctgg cttgaagatg gaagagatac aagcagaatc gtctaatgaa aaaactgaag
    11821 aattttcaga attgctataa gaggttatga aaatagtgtt ttgaccagag tattagagaa
    11881 acaaaacgaa aaaatagctc catgtatttt accgtttttg aactaatgtc gaagattagc
    11941 tgattgaata ccatttatca agaagttatg gaaaagccgg ttctttttta ctaactgaaa
    12001 aataaaattt tatttagaga tcaagctaca gttgataaat gatataaaaa agagaatttc
    12061 ccatgaaata gcgaggttgt gacaaaagtg ggcagcttca agaaataaga aggaatttac
    12121 gaaaattgct tttcaaattt ttgtgaaatt tcggcttatt tttcgaagaa gttacttctg
    12181 gaacaccgtg tatcagaggt tg
//
LOCUS       DAFLVO010000080        12120 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.081, whole genome shotgun sequence.
ACCESSION   DAFLVO010000080 DAFLVO010000000
VERSION     DAFLVO010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12120
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.081"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(12..569)
                     /gene="frr"
                     /locus_tag="L1U99_002378"
     CDS             complement(12..569)
                     /gene="frr"
                     /locus_tag="L1U99_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBN1212900.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(572..1294)
                     /locus_tag="L1U99_002379"
     CDS             complement(572..1294)
                     /locus_tag="L1U99_002379"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBN1212901.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1430..2311)
                     /locus_tag="L1U99_002380"
     CDS             complement(1430..2311)
                     /locus_tag="L1U99_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBN1212902.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2410..3192)
                     /gene="rpsB"
                     /locus_tag="L1U99_002381"
     CDS             complement(2410..3192)
                     /gene="rpsB"
                     /locus_tag="L1U99_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBN1212903.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3551..4030
                     /locus_tag="L1U99_002382"
     CDS             3551..4030
                     /locus_tag="L1U99_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HBN1212904.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4247..5338
                     /gene="phnW"
                     /locus_tag="L1U99_002383"
     CDS             4247..5338
                     /gene="phnW"
                     /locus_tag="L1U99_002383"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBN1212905.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5331..5459
                     /locus_tag="L1U99_002384"
     CDS             5331..5459
                     /locus_tag="L1U99_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBN1212906.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            5463..6008
                     /locus_tag="L1U99_002385"
     CDS             5463..6008
                     /locus_tag="L1U99_002385"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBN1212907.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6462..8153)
                     /locus_tag="L1U99_002386"
     CDS             complement(6462..8153)
                     /locus_tag="L1U99_002386"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBN1212908.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8573..9520)
                     /gene="arcC"
                     /locus_tag="L1U99_002387"
     CDS             complement(8573..9520)
                     /gene="arcC"
                     /locus_tag="L1U99_002387"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBN1212909.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9635..10654)
                     /gene="argF"
                     /locus_tag="L1U99_002388"
     CDS             complement(9635..10654)
                     /gene="argF"
                     /locus_tag="L1U99_002388"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBN1212910.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10745..11974)
                     /gene="arcA"
                     /locus_tag="L1U99_002389"
     CDS             complement(10745..11974)
                     /gene="arcA"
                     /locus_tag="L1U99_002389"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HBN1212911.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         3310 a         2518 c         2193 g         4099 t
ORIGIN      
        1 ttatgatttt attaaacttc caataattct ttttctttat cagcagcgat cttatctact
       61 tctttgatgc tgttatctgt caatgtttgt acgtcttttt ctaatccgcg caaatcatct
      121 tcggtaatat caccattttt ttgttgtttt ttatattcat cgatcgcatc acgacggatg
      181 ttacgaatcg cgatttttgc attttctgct tcttttttaa catctttagc taattctttt
      241 ctgcgttctt ctgtcagttg cgggataact aagcgaatga catttccatc attggttgga
      301 ctgattccga tatcacttgc cataatagct ttttcaacat cttgaagaat gctcttgtca
      361 aaaggtgtga tcattaaaac acgtgcttct ggaatttgga ttgatgccat ttggttcaat
      421 ggtgttggcg caccgtagta gttcacagta atacggtcca aaaggctagc gttcgcacgg
      481 cctgcgcgga tttgcccaag ttcacgttga agattttgtg ctgctttttt cattttttct
      541 tttgcttctg tcataattgc atctgccatt tttatttccc ccttacagtt gttccgatat
      601 tttcgcctaa gattgcacgg cgaatatttc cgtgttcatt taaattgaag acaagcagtg
      661 gaatatcatt atccatgctt agtgaacttg cagttgaatc catgacttgt aatcctttgg
      721 caataacttc cagatgagtc agttcttcaa attttactgc atttgcatct actttcggat
      781 cagcagaata aacaccgtct acattgtttt tagccatcag gataacatct gcgccgattt
      841 ctgccgcgcg taatgctgct gttgtgtctg tcgagaagta cgggttgccg gtaccgcctg
      901 caaagataac gatccgtcct ttttctaaat gacgttctgc tttacggcga atatatggct
      961 ctgcgatttg acgcatttca atcgaagttt gcacgcgtgt cggtacaccc acgttttcca
     1021 acgtatcctg taaagctaag gcattcataa ctgtagctaa catacccatg taatcagctt
     1081 gagcacgttc catgcccatt tgtgctccga tttgtccgcg ccagatattt ccgccgccca
     1141 caacgattgc catttcaacg cccagctcgt gaacttcttt gatttcttgg atgatttctt
     1201 tgattactgg tggtttgatt ccaaatcctg cgtccccagc taaagcttct ccactcaatt
     1261 ttaagactac acgctgatat ttcggtgtga ccatgttcat tcctccaata ttttctattg
     1321 ccattttacc atacttagat gatttcgaca ctctaagact ggtttttctt gttttgctta
     1381 aaaaaaggga gcgcacaaac cgtgcgttcc cgtctgttat tcaacagaat tattttttca
     1441 cttggctcat aacttcttct acaaagttat cttcgcgttt ttcgatacct tcgccaactt
     1501 cgaaacgtac gaatgtttta acagttgcgc cttttgatgc aacgtatttt tcaacagtca
     1561 tatcaggatc tttaacgaat ggttggtcca ccaaagcgat ttctgctttg aatttcttca
     1621 agcgtccttc taccattttt tcaacgatat tcgctggttt gccttcgttc aatgcttgtt
     1681 ctgtaagaac agttttttca tgttctaatt cagcttctgg aatttgtgat tcgtttacat
     1741 aacgaggatt gatagctgct acgtgcatag ctacgtctct tgcaactgtt tcgtcagttg
     1801 ttccatctag aacagtcaat acggcaatac gtccgcccat atgcaagtat ccaccaaatg
     1861 cagcattgtc gtctttttct acaacttcaa agcgacggaa gctgattttt tctccgataa
     1921 cttgagttgc ttcgatcaag tcagattcaa ttgtaccttt atctgttttg attttcattg
     1981 cagcttccat gtctgctggt ttgttttcag caacaagttc tgcaatttct tttactaaat
     2041 cttggaacat ttcgttttta gaaacaaagt ctgtttctga gtttacttca acgattgctg
     2101 cagtgttacc tttcacagca actgaagcca atccttcagc tgcaatgcgg tcatttttct
     2161 tcgcagcctt tgccattcct ttttcacgta aaagatcaac tgctttttcc atgtcgcctt
     2221 ctacttcaac taatgctttt ttcgcatcca tcattcctac gccagtcatt tcgcgtagtt
     2281 cttttaccat tttagctgta acgtctgcca tgtttaactc ctcctgtgtg tttttctttt
     2341 taaaaaaagc tgcttcaaag gagagtgagg cttgtcgccc agcctttgaa acagctccat
     2401 cattcaaaat tattctgctg aagaattgtc gccttcaaca acatctacga tttcttcgat
     2461 tgatgttgct gtgttttctt ctgtgaaatc ttcttcaact acttgatctt caccttggtt
     2521 tccttcgatg aaagcatcag ccatttttga agtaatcaat ttaacggcac gaattgcatc
     2581 gtcgtttgaa gggattacta cgtcgatttc atctggatcg cagtttgtat caaccatagc
     2641 tacgattggg atatttaatt tgtgtgcttc ttgaacagca atacgttctt tacgtgggtc
     2701 aacgatgtac attacatctg ggattcttgg catatcagcg ataccgccta agaatttttc
     2761 aagacgttca cgttctttgt tcaaaccagc aacttctttt ttaggtagaa cttcaaaagt
     2821 tccatcttct tccattgcat tgatttgttt caaacggctg atacgttttt ggatagtatc
     2881 ccagtttgtc aatgttccgc ctaaccaacg atggttaacg aagtattgtc ctgcacgagt
     2941 tgcttcttct ttgattgctt cttgtgcttg tttttttgta cctacgaata atgctacgcc
     3001 gccttcttca gcaacgctct tcatgtaatc ataagctgca tctactaatt taactgtttt
     3061 ttgcaagtca atgatgtaga ttccgtttct ttctgtgaag atatatttct tcatttttgg
     3121 attccagcga cgagtttggt gaccaaagtg tacgccggct tctagtaatt gtttcataga
     3181 aattactgcc atgtttgttt cctccgattt ggttttattt ttcctcttct tatcttctac
     3241 cttgccggca aactttttca agcacctacc gacaatccaa taagaatgtg gatttgctga
     3301 tgcataaagc accctcagct attatacaga caaaagatcc gtatcgcaag agcaaatata
     3361 cttttctgct caacattcaa tagtttacct gaaagataaa aagaattcaa gaaaaacagt
     3421 agatttctct ttgtttcttt attatccttt ttccataaaa taattttagg tataaaagac
     3481 gaatattatt gggcaatcct tctttttttt gttatgatac atgtgaaatc tttcgtaaag
     3541 gagaaagaaa atgcgcaaag ctcaaagaca tttgctgatt aaacaagtca ttgaagaatt
     3601 cccgatccgt acgcaagaag aactattaaa caaacttggg cattatggcg ttaccgccac
     3661 gcaggcaacg atttctcgag atatccgtga tctaaaaatc gtgaaggcac ctgatgaaaa
     3721 tggcgtttcc cgcttcgtat tgtttcgcga aaaaggaact cctgagacta ggactgagga
     3781 agaggatcgg ctggttcaaa tgattgaaga cattgtattg aaagtcgaac gagtccactt
     3841 tttgacgatc gtcaatacct tgccagacaa tgctcattta tttgcatctg ttttagatga
     3901 gatcaaacct ccctctattg tcagtacaat tgctggattc gatacgatca tggtcatctc
     3961 ggaaaatgag gaggacgcaa aacgagtaga agaatttctt caccatccaa ctgaagtatc
     4021 acttttttaa tcagagcacg tattcctaat atggaatgcg tgttttttta ttttcaatat
     4081 tttccttatt gaataaacct ttacactctt tacaaaaata catcattttt tattcaaatt
     4141 tttcaacacc ttgattgaat cacaataatc atcatttata ttggatgtta acaagagcag
     4201 cttcttgctc tttgtgtatt tcaaaaaaga aatgaaagga aatcatatgt ataaattatt
     4261 aacttctgga ccattgacga cttctgaaac agtgaaaaat gctatgctga tcgatcattg
     4321 tacttgggat caagaataca aagaaattac acaatggata agaaaaaaat tattggatct
     4381 tgctcaagta tcggaaggaa tatacacaac ggtcttaatg caaggtagca gctccttcgg
     4441 ggtagaatcg gtattaagtt ctgtgatcag gccagaagat actgtactga tttgttcaaa
     4501 cggcgcatat agacaacgaa tgatcaacat gtgcgaatgt ctgaaactga actataccgt
     4561 ttatgaggta tcggaacatc aaatcctcca agctcatgtg attacacagc tgattgaaga
     4621 gaatccgtct atctccgcac tagcaatggt ccatagcgag actacttccg gtattttgaa
     4681 taatttggaa gagattgctg ctgtcacaca agaaagagat cttttgttta tagtggacgc
     4741 gatgtcaagc tttggtggga taccgatttg tgtagccgaa ctagggattg attttttgat
     4801 ttccagctca aacaaatgta ttcaaggtgt tccaggcttt tcttttgtac ttgctaataa
     4861 agcggaactg gaaaaacgaa aaaatgttag ccgaagtttg tcacttgatc tatatgacca
     4921 gtaccgcgtg atggaaaacg agaatggcaa atggcgtttc acttccccta cccatacggt
     4981 tttggctttt caacaagcgc tgaaggaact agaggcagaa ggaggaatcg aaactcgata
     5041 ttcacgttat ctcgccaata atcatgtgct acgacaaaaa atgacagaga tggggttcca
     5101 gcctttcatt caagaatatc aggggccatt catcacctct tttctttacc ctaaggactg
     5161 gcgatttgat tttaatcatt tttatcagta tttaaagcaa aatggatttg tgatctatcc
     5221 cgggaaaatc agcgatcatg aatgttttcg tatcggaaat attggcgaga tctatccgga
     5281 agatattttg gaactgacag caattatcaa agactataag gagaacgtta atgattaaaa
     5341 ctgtaatttt tgattgggca ggaacaactg tggactttgg ctgtatggct cctgtccacg
     5401 cttttagaaa tgcttttcta gaaaaaggaa tccaactgac tgacaaagaa atccgctaac
     5461 cgatgggaaa attaaaatgg gatcatatcc aacagcttct ttccctccct tctgtcaaaa
     5521 aacaatggat agctatttat ggacaactac ctcaggaaaa agaggtggag gaattgtatc
     5581 aacaatttga acattatctg tttaaagatt tggtcaagca ttctaccttg aaacccgaca
     5641 cattggaaac gatcgaacgg ttgagaaacg ctgggatcaa tattggttcc acgaatggat
     5701 ttaatgctcc tatgatgaca atcgtagcag aaaccgcaaa aaaagaaagg tattcaccag
     5761 acttcatggc aacttttgaa gacgtcgaag ggtatggtcg accgtttcct tatatgatcc
     5821 ataaaaacat gcagtacttc aaaaacaagt cggttgatga agtaatcaaa gtcggagata
     5881 cggtctcaga tatccaggaa gggaaaaatg ccggagtgtt gacagtaggt gtaattgaag
     5941 gtagttcgct aatggggatt tcttatgatg agtaccaaaa attagagatg gggaaaaaga
     6001 tcgtttaaaa cagtctgttg ctcttagatt ccaacaagcc ggcgctgata tttgtgtaaa
     6061 caatttaaaa gagttaacag aatacatttt gtacgctgac atgaatccag aatgactttt
     6121 atacaaaata agaggttgtg aaaaagctgt cctgtatcaa gtaataaaaa cagccaagca
     6181 aaaatagctc ctcatatttt tcgtttggtt aggcttatta ccgcagatgc aagcttttga
     6241 acaccgttta ttcgaaaaaa aaaagggagc tgtgacacga cttttgtcac agtcccctta
     6301 tttgcaaaca aacagtgttt aagagacaac ctctccacta aacggtgttc attcagctga
     6361 ctctcggtat ttgctcaaaa aacgataaaa tttgaaaagc tattttctct tttgtttctc
     6421 taatactcgg atcagaacgc tgatttcaca ttctcttttt cttacatctt atctggtgca
     6481 tgaagtccta gcaaacgaag gtcttctttc aataatacag tcactgcata aactagagct
     6541 aagcgtgctt ctttttgttc atcatcagct aaaatcttcg tatgagcata gtatttgttg
     6601 aatgcttgtg ctaatttgat tgcatgtttc gcaatcactg acggttcgta tttttcccca
     6661 gcagacaaga ccgtttcagg gtatttttga actaatttaa ccacttccca gctggtatcg
     6721 tcattcaatg catagtctgc tgtttctgaa gggacaaatc ctgctttttc caacaggctg
     6781 actgcacgag catgtgtata ttgcacataa ggtccagttt ctccttcaaa tcgaacaact
     6841 tcttccaggt taaagtcaaa tgtattcagt cgatcgtttt tcaaatcgtg gaaaatgact
     6901 gccccaaccc caacttgttt agctacagca tctttgtttt ccaaatcagg gtttttctcg
     6961 ctgatttgtt ctttagcaga ttggattgct tcatttaata cttcttctaa taagacgatc
     7021 tttcctttac gagttgataa ttttttacca ccttgcgtga tcaaaccaaa tggaatatgg
     7081 tgcatgtcgt cagaccagtc aaagcccatt tccttcaaga cagctttcaa ctgtttaaaa
     7141 tgatagcttt gttcattccc tactacatat agagattgtt tgaagtcgta agtacgttta
     7201 cggtacaatg cagcagctaa gtcacgtgta atgtatagtg tcgcaccgtc tgacttctta
     7261 atcaacgctg gattcaggtc ataagcagat aggtcaacga tctctgcacc tttatcctcg
     7321 ttcagcaaat gtttttcttc taaaagtttg acgatttcat ccatcttgtc attgtagaaa
     7381 gcttcaccgt tcaacgaatc gaaacgtact tccagcagat catagatttt attgaattct
     7441 ttcatcgatt catcacggaa ccattgccat aattgaatag cctctttatc gccttcttcc
     7501 agacgtttga accaagcacg agcttcttca tttaattctg gttctgtttc agctacttca
     7561 tggaattgga cgtataaacg aagcaattca ttgattggtt ctgctttaac agcttcttct
     7621 gtaccccatt ttttgtaagc gacgatcagt tttccaaact gtgttcccca gtcacctaaa
     7681 tggttgatgc ggattggctg ataaccgatt ttttccataa tgaaaccgat cgaattaccg
     7741 ataactgtcg aacgcaaatg tcccattgag attggtttgg caatattagg agaagacatg
     7801 tcgattggta ctgttccttg attcccgatg ttgctatccc cataatgttc tttttctttc
     7861 actactgttt gcaaaacttt tttgctgata agttctttat tcatgaaaaa gttcaagtaa
     7921 ggtccgacaa cttcgatttt ttcaaagttg gcagaatcga ttttttctgc taaatctgca
     7981 gcgatttgct gtggcgcttt tcggtaaact tttgctaatg aaaaggctgg aaatgcaaca
     8041 tctccgtgtt cagctgattt tggattttct agtaattgct cgacttgttc cagtgttaaa
     8101 tcatctttga cagcgtcata gacagctttt gcgacaagat ctttattatt catctttatt
     8161 cctcctaaag tgttcccttg attgttaaac aaaaaaaatc tctagcgacg gcatacttag
     8221 tatgccatca ctagagacga gatttcccgc ggtaccactc caattgtcct aaaaaaggac
     8281 cagctccatc tgatatcggt agacgaccgt ctgtttaaaa cagaattctc caagtgcgct
     8341 tcgttgtatc ttcttcattc ggcttccacc acttccgaat tcgctagcca agaatgatac
     8401 aagtactctc ttgttcaaca aatcttagtc ttattaaact ttcttgaatt atatcagaaa
     8461 aaaaaacgaa aggctagtcg tttcataaaa aaacaatcca gatggcctaa aggagaagaa
     8521 ataccacctg gatagctata aatcatttcg taaatacgaa agacttaaca aattaatcag
     8581 ctacgataat cgttccttct tcagaagcta aaagattctc gatattttct aaagaagtga
     8641 tgattgcctt agcgtttggt tttgcttcaa caaatgcaat agctgcttct actttcggaa
     8701 gcatgcttcc tggagcgaat tgcttttcat caatgtattg tttcatttct gaaacagtaa
     8761 cagtttctaa tttcttttga tctggttttt ggtaattgac atacacattg tctactcctg
     8821 tcaatacgat cagcaaatcc gcatcgatga tttcggctaa tttttctgaa gcaaaatctt
     8881 tatcgattac ggcttctcgt ccttctaatc cagtagctgt ttctacaaca ggaatcccac
     8941 cgccaccaac agagactgtg ataactcctt gatcgaccag cgtttcgatg acacgtgctt
     9001 ctttaatcga gatgggttta ggggaagcga ctacttttct ccatccacgt ccagcatctt
     9061 ctttgaatgt cacagtggag tcagcattca tttgttcttt ggcttcttct tccgtgtaga
     9121 atggaccgac tggtttactt ggatttttga atgaaggatc attttcatcc acaataactt
     9181 gagtgactaa agaaaccaca tctttatcga tccctttttc cttcagtact tcgcccatgg
     9241 cgttttgtaa ccagtaaccg atagatcctt ctgtcattgc aacacatgta tctaaaggca
     9301 ttgccggtgt tttctcagaa tcagcagctt gctgctgaat caataggtta ccgacttgcg
     9361 gaccatttcc gtgggagatg atcaattcat ctccttgttc gataaatttc actaaatact
     9421 ttgctgtttc cattaacgct tcttgttggg cttttgcact tgcatccgta gacaagatgg
     9481 cattgccccc taaagcgaca actacttttc gtttggccat ttcattcgtc ctttcttcag
     9541 ttctaccgaa ttttctagat aacaaaacga gccagcgttt tgtgattttc cctcaatgct
     9601 gactcgtttt ttcgtgagat gaatgtggtt atgcttaaac gcgagggata aacaagttac
     9661 ctaatgttgc tgccatgatc gctttgattg agtgcatacg attttctgct tggtcaaatt
     9721 gacgagcata tttgctgcgg aagacttcat ctgttacttc catttcagtg atgccaaagc
     9781 gttctttcat ttgttcaccg taaacagtgt ttgtatcatg gaaagctggc aagcagtgca
     9841 agaagatcaa acgatctgtg ttgtgtgttt tttctaccat ttccatattg atttggtaag
     9901 gtttcaacaa tttgatacgt tcttcgaatt tatcttcttc acccattgat acccatacat
     9961 cagaataaag gacgtctgct ccgtctacac ctttatcaac atcgtcggta atcatcaatt
    10021 gtgcaccgga tttttcagca aagccttctg ccattttgac gatttcttct tcaggttgta
    10081 attcttttgg tgcaacgata cgcatattcg ctcctaaaat tgcacctgtg actaataaag
    10141 agttagccat attgtttcga ccatctccgc agtaagcaac agtgatacct tctactgttc
    10201 caaagttttc ttggatagtt aaaaagtcag cgatcatttg tgttggatgc cattcatcag
    10261 tcaagccatt ccaaactgga acaccagaga attctgctag ttcctctacc attttttgac
    10321 tgaatccacg gaattcgatt ccgtcaaaca tacgtcctag tactttagct gtatcttctg
    10381 tggattcttt tttacctaat tggatatcat ttgcacctag atattcagga tgtgcaccta
    10441 gatcgatcgc tgcagtagta aatgcagaac gagtacgtgt agatgttttt tcaaataaaa
    10501 gcgcaatatt ttttccttct agatagtgat gtgggatacc acgttttttc aagtctttca
    10561 agtgttctga aaaatcgatc aaatattgta attcttcttt tgtaaagtct ttttctgcta
    10621 ataagcttct tccttggaat actgattctt tcatattaaa cattctcctt tagattgttt
    10681 ttatttaaga ttaaagagga aatcccgacg gcagctgaca gtaagactgc cgtcaggaaa
    10741 caaattactt caagtcttca cggacaagtg gttggctcat gcagcgtgga ccaccacgac
    10801 ctcgtgacaa ttcacttgaa ttgatttcta acactttgat gccatagcta cgaagcaatt
    10861 cgttcgatac ataatttcgg ttataagtga ctacaacacc tggagcgatt gccaatgtgt
    10921 ttgatccatc attccattgt tctcgaggtg caacgatctc atctccatta ccagttggga
    10981 tcagtacaag atcatctaat ccaagagcag ctttcatcgt ttcgtgtaag ttatctgaat
    11041 gagtaatctt gatatcatca ccatctggtt cgattgtaaa gacatccatc ttaccgtctt
    11101 tactttgaat tgctggatgg atagtgaatt tatcgtgatc taccattgta aatacggtat
    11161 ccaaatgcat cattgcacgg ttgttcggaa ttttgattgc caacactttt tcaaatcctg
    11221 aattttttgc gaataggtgg cgtgctaatt tttctaaagc tttcgcatta gttcgttgag
    11281 aaatcccaac agctactact ttatcgctta agatcaattc gtctccgcct tcgatatgat
    11341 ctggattttc acgatccaac catacttcga ttcctttatt tgcaaatctt ggatgatgtt
    11401 tcaaaatata ttctgtaaac atcgattcac gacgacgtgc ttcaaaagtc atcttattga
    11461 ctgtcatccc atttcccatt gatgcggaag ggtcgcgtgt aaagtacaag tttggcattg
    11521 ggtccatgta aaatggatag tcatcgtctg ctgacagatc atatagactg ctagaacgta
    11581 cttcgatatc ttttgtacga accccagcca tgattttatc taccatttct tgcgtttcca
    11641 ttgatagaag gaactcatga agaccctctc ttacagcatt cgatgcaata tgagattcat
    11701 ccaacatttt attcaagaat tgttctttga cattgcctgc gtcaatcgct tctgccgcta
    11761 atttttccaa gtaaagagtc tcgacgcctt cattttgcaa tgtcttcgca aagttgtcat
    11821 gttcttcttg agcaatcgga agatatggaa tatcatcgaa caacagacga tccataatat
    11881 ctggtgtcaa attttccact tcttgtccag gccgtttcag taaaactgtc tttaatttcc
    11941 ctatttcaga gaaaacgtga ataggtttat ccatgttgtg ttgcctcctt ctttttgatt
    12001 acatgtatag gatatcctcc ttttgtaatc actttcataa ttttgtctca ttcaaaatga
    12061 gacattcctc acattaatat tcgataatta aataattaaa cgtttttcta tttttaagcg
//
LOCUS       DAFLVO010000081        11755 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.083, whole genome shotgun sequence.
ACCESSION   DAFLVO010000081 DAFLVO010000000
VERSION     DAFLVO010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11755
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.083"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..177
                     /locus_tag="L1U99_002390"
     CDS             <1..177
                     /locus_tag="L1U99_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1212912.1"
                     /translation="YLLGMALAYSVGSLIKVNVSLDLFTILLAVGVSSVIGLVFSVMP
                     ASEAAKKDLIDILR"
     gene            578..1183
                     /locus_tag="L1U99_002391"
     CDS             578..1183
                     /locus_tag="L1U99_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HBN1212913.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            1199..1771
                     /locus_tag="L1U99_002392"
     CDS             1199..1771
                     /locus_tag="L1U99_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1212914.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2023..2280)
                     /locus_tag="L1U99_002393"
     CDS             complement(2023..2280)
                     /locus_tag="L1U99_002393"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212915.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(2406..3221)
                     /locus_tag="L1U99_002394"
     CDS             complement(2406..3221)
                     /locus_tag="L1U99_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212916.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            3738..5063
                     /locus_tag="L1U99_002395"
     CDS             3738..5063
                     /locus_tag="L1U99_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBN1212917.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            5056..5406
                     /locus_tag="L1U99_002396"
     CDS             5056..5406
                     /locus_tag="L1U99_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212918.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            5388..5573
                     /locus_tag="L1U99_002397"
     CDS             5388..5573
                     /locus_tag="L1U99_002397"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212919.1"
                     /translation="MGSIRMNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSF
                     YVEAAAGYHKYEYYIGY"
     gene            complement(6477..6752)
                     /locus_tag="L1U99_002398"
     CDS             complement(6477..6752)
                     /locus_tag="L1U99_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HBN1212920.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(6724..7677)
                     /locus_tag="L1U99_002399"
     CDS             complement(6724..7677)
                     /locus_tag="L1U99_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBN1212921.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            8289..9782
                     /locus_tag="L1U99_002400"
     CDS             8289..9782
                     /locus_tag="L1U99_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HBN1212922.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            9917..10213
                     /locus_tag="L1U99_002401"
     CDS             9917..10213
                     /locus_tag="L1U99_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBN1212923.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            10314..11165
                     /locus_tag="L1U99_002402"
     CDS             10314..11165
                     /locus_tag="L1U99_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212924.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            11186..11469
                     /locus_tag="L1U99_002403"
                     /pseudo
     CDS             11186..11469
                     /locus_tag="L1U99_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         4041 a         1811 c         2179 g         3724 t
ORIGIN      
        1 tatttattag gaatggctct tgcttatagt gttggttctt tgataaaggt aaacgtgtca
       61 cttgatctat ttactatttt actagcggtt ggggtatctt cggttattgg actggtcttt
      121 tctgtaatgc ccgcttcaga ggctgcaaaa aaagatttaa ttgatattct tagataaaat
      181 cagaatgaca agaatattta cgttctagat tctaaaataa aacacaaaga gaccaaccag
      241 gcaccctatt gtttctttgt agtatagaga tattctttgg cttgtaagag atcaatagag
      301 ttaggtgacc ggagttcgaa ataaaggaaa tttttgattg tataggagaa ttctttatcc
      361 ctaatattta gaattttgag tatgccatgt tgatgtttta gattctctat aaatatagag
      421 gtgtatcaaa ggtcaactag actgtgcaaa atagagacac ttgaaaaatc tatcgggggt
      481 cagaaactta atagtttttg acacataaac aaaatcgcga tataatgggg ttgagagtgt
      541 ttcataaact tatgtcataa agttaaggag atttcgcatg attttagaga ataaattggg
      601 attaaccaat caagttgagt tggctaaggt tgaagaaaaa ctcagtaaac aaaaagcgaa
      661 agaattgtac gattgtggaa aaataaatga aatcgaagtt ggtacattta aaggtttatc
      721 tgaaattcat gaatttctat tttcggatat ttacgatttt gccggaaaaa tccgatcggt
      781 caatattgca aaaggaaatt ttcgatttgc accagttatg tatttagaac attcgttaca
      841 gcatattgat cagatgccac aaacttcttt tgaagagatt atcaagaaat atgtggagat
      901 gaatatcgct cacccatttc gagaaggaaa tggccgaagt actagaattt ggctggatct
      961 cattttaaag gaagaattgc aaaaagttgt agattggaac ttaatcgata aagcagacta
     1021 tctttctgca atggagcgaa gtcccataaa cgatttggaa atacgctatc taatttccaa
     1081 tgctctgact gataaaattg acgatcgcga gttatatatg aaaggaatcg atgtcagcta
     1141 tttctatgaa gggtattctg agtatacgat agatgatttg taaaagtagg tggaccaaat
     1201 gacgaaatat ggatatgcac gtgtctcaac cgcttctcaa agtacaaaag aacaaattca
     1261 acagttgctt gagaacggcg tagagaagaa gaatattttt tcagaaaaat ttacgggtac
     1321 aaaacgggat cggccaaaat tcaatcagct gttggctggt ctgaagcctg gagatgaaat
     1381 agttgttacg aagcttgatc gatttgctcg taacacgaga gaagcattag agatcattga
     1441 acctttactc gatgataacg taacgatcaa ggttttgaat ctaggaacga ttgaaaatac
     1501 gtccatgggg cgaatggtga cacggacgtt gttgagtgta gcagaaatgg aacgtgatat
     1561 gattgtggaa cgtacccaag aaggaaaaat gtttgcaaga aagaataatc ctaatttcag
     1621 agaaggacgt ccgaaagcaa caatcacacc gaagaagagg cacgcatatg aactgcttac
     1681 ttcaggtaaa tcgtataagg aagttgaagc tataaccggt ttcagtcgca gtacgctttt
     1741 tagaataaag aagaaaattg aagaaagtta aaaaagaagt ctcagcgaac cagacaggta
     1801 aatacttaat gcgttctaga tatgagtcta ttagcatgtt gtgaaatata atattttttt
     1861 atttacttga tttctgctca aaaaatgtgt atggtaactg taaaaggtaa agtaattaaa
     1921 ggtatgctag ccacgcttac tatattagga taccatcata tatttataat gaacgatttg
     1981 ttcgtctacc aaacaacaca tatcgttcag cgtaagtcac gtttaggaac gtggcttttt
     2041 tagtgttatt atcgataaat aatctattga ctctattgat tttatctcca tatccctacg
     2101 gtgttgattg tctttagatc tttcatttaa gaaccaaata actatcataa aaatcagcac
     2161 tgctgctaat ataataaaca gcattcctat tgtgatatta cctattgatt ttaccataac
     2221 tacgattaaa gtaataatgg cattcaagtc tcctttgttc tctatatata aattagccat
     2281 aaatcatctt cctttcaaat taagatactt gtttgatacc aataaatagt aagcgtggct
     2341 agcatacctt tttctgtaat agcaagtgtt ctaatagtcc aaacttaatg atggaccgat
     2401 gctagttata gtacagtaat gttttctttc ttatctagat ttttagtaag ctctatcagc
     2461 aaatctaaca aatctgagtc cttttcagaa actaaattaa atctagtgtt tacaacaaag
     2521 ttttcatgtt ctatattgtt tagattattt gcggaaagga gggcttctag atcttgacat
     2581 tcaaatctat atgcatcgtc ataaatctta ctagaaggag tgcttaattc gaaattactt
     2641 attttctcat cttggaccaa gataaattta tagatagtat ctttttgtgt ttttctttta
     2701 aaaacacaac agagtgtgtt ataaggaacg ttataatttt catcagcctc attttttctc
     2761 cattcaaaca aatgataaac tgcaaccaag ttgccatcaa tttcatggac agtgctctcg
     2821 gtaacatcct ttaaagaact atcaagggct aatttatagt aactagagag aggaagtaaa
     2881 attgtcgatt tactgagatg gttatcgtct atacgtgcaa tcatacctaa atcaactaag
     2941 gttttattcc aggtgtttat agttttagtt gtcactccta gagactctgc tatggtattg
     3001 accgaatgcc aggaatcccc gccttcattc tttgccttaa aacagtaata cagatataaa
     3061 ttaatagctt tgttattcgg taaatatttt tcaagttctg ttggtagaat aaagtaagaa
     3121 tccttaatgt tttttctgaa ctgtctccag tctctgtagt tttgtttata aagttgtgaa
     3181 acggtttttc cacctttaga aagtcctgct atcttaacca atcttattgc tcctttcttg
     3241 aatctgtcat gatcatacag tattttttac ttgtagtcca gcaccttaat atattatcct
     3301 atgtaattaa tttcgtacta gatagtaatt attttttatt taattctcta gtcacttaca
     3361 aataagttat ataaactacg attaataaat tattacaaaa actattaaga aaacttctac
     3421 atacaactat tacaaaacta ttaagaaact gaatactcct attttttgtt tttaaggaaa
     3481 gttttttctt ttttgaattt cttatttttt tctaatataa ctaagcaaaa ctggataata
     3541 cgacacttat tttcaaattt tcacaagact aatagtaaat atccatttaa taaagtgata
     3601 caatgtgttg attttacaaa tcaacagaag aagtagggaa ataacttacc tatgcttctt
     3661 tttttgtaca tttaatcgat tcttctttac aaaaacgaac gtatgtttgt ataatgtgga
     3721 agaatggagt gttatttatg atggattatt caaaagagcc agtaaatgat tactttttga
     3781 tcgatatgaa aagcttttac gcaagtgtcg aatgtataga aaggaattta gatccattaa
     3841 cgactgaatt agtcgtcatg agtcgagcgg ataatacagg atcagggttg attttagctt
     3901 cttcaccagc tgcaaagaag aagtacggta tttctaatgt cagtcgacca cgagatctac
     3961 cgcaaccttt tcctaaaacg ttacatgtcg ttccaccacg catgaatctc tatattaagc
     4021 gaaatatgca ggtaaacaat attttcagaa ggtatgtagc agacgaagat ttattgattt
     4081 actcgatcga tgaatcgatc ttaaaagtga ccagatcaat gaatcttttt acgactgaag
     4141 gaacaagaag tcaacggaga aagaagctgg ctcaaatgat ccaggagaat attaaagaag
     4201 agctaggatt gcttgctaca gtaggtgtcg gagataatcc cttattagct aaacttgctt
     4261 tagacaatga agcaaaacat aatgatggat tccttgctga atggacgtat caaaatgttc
     4321 ctgataaagt atggaatatt cctgaaatga cagacctttg gggtattgga tctcgaatga
     4381 aaaaaagact caaccaaatt ggtatcatga gtattaaaga cttagctaat tggaatccat
     4441 acactattaa gagccattta ggtgtgattg gcttacagct gtattttcat gcgaacggga
     4501 tcgatcgaac agatatagcg atcccaccag aaccgacaaa ggaaaaatca tatggtaatt
     4561 cacaagtgtt accacgagat tataccagga gaaatgaaat cgaactggtg gtaaaagaaa
     4621 tggcggaaca agtagctatt cgtatcaggc aacataactg taaaacaggt tgtgtccatt
     4681 tatacattgg cacgtcgatc ttagaaacga gaccaggttt ttcacaccag atgaagatcc
     4741 ctataacaga taatacaaag gaattgcaga attactgtct tttcttgttt gataagtatt
     4801 atgaaggaca agaagtaagg cacgttggaa taacctatag caagcttgtg tacactgatt
     4861 cgcttcagct ggatttattt agtgatccac aaaagcaaat tgacgaagaa aatttagata
     4921 aaattattga caagattcgg caaaaatatg gttttacgtc gattgtacat gcttcttcta
     4981 tgttagaagg cgctcgtagt attactagaa gtacattggt tggtggccat gcaggcggcg
     5041 caggagggct taaaaatgat tgattataat gatcgtggac gtttaaagtg ggcaggtttt
     5101 tatttatctg atcatactga aaaaattgat gccgacaatg aacaacgagc caatcaaaat
     5161 ttggcaaaag aacaaatgac gactgaagag gttgcggaag tattgaacgc tgcagtcata
     5221 aaaaatagat cagtatgtat tcaaaaagaa gaacgaaacg ctgaaggata ctatccagaa
     5281 gatattgtta gcaagatctt aggtagtgat gagctgggga tctacgttgg aaaaaacaaa
     5341 gttcactacg acgaaatacg tcatatcgaa ttttaccagg ataataaatg gggtcgatta
     5401 gaatgaacat tatccagcaa tatgagctaa agtatataac ctttgatcag ctatcagaag
     5461 agatttgggg ttatggccag cgtttgataa atgaggttgg tgttgaacgc ttctctttct
     5521 atgtagaagc tgcagcagga taccataaat acgaatacta tattggctat taaagtgcaa
     5581 taaaattata tttcttttat gttttacatt ttgtatcaat tctgataaaa ttacctatag
     5641 gtaattaaaa aatataaaaa aactagttac aaccttagga cgttgtaact agcttgaagc
     5701 atactagagc taactaaaat agcactagaa agcaatgtta aacccgtcca acaaacttga
     5761 tttaacattg agaccagctt attcagctaa atatagttga ataagcttct tttgttttaa
     5821 aaaaacaaaa ggtgtactac gaataacgca agtaaaagaa atactattac aaccagtagg
     5881 ctacaagtaa gtattactaa acattgcgta gttagaacct ttgctctatt gtctaaagcc
     5941 acaaaattag agatcagctt tatgatgcta agagcgagct gcatccatgc ggacataggt
     6001 tcttttgaca ctattaattc tcctttttag gataagggaa attgctagta gttttttcat
     6061 tagcaccatc ccccttcatt tgattgagtc tagtgctgct gtgatagttt gctgtttaat
     6121 atgcttacat tcttattata acataaatga aacaaacaca tggttagagg tcgtatcaat
     6181 caaaatagtg tctcacaaac gatttattac ttactcctgc tgactaacgg actgttcttc
     6241 agtaactgta actatatgtt tgttaaaacc accattacct gtagataaaa accaatatat
     6301 ttactatact cactatatta aatatattta gtatagtaaa aactagaaac aataaaattt
     6361 gtgaatgttg tataccccca aacaatacac atattttgaa ggattaggat taataaagct
     6421 aaaaatatag taagtatact aaatatattt actatatcta gtatacttac tatattttaa
     6481 tcttttgatc gtctattata tataatccgt tcctcgtcgt ttaaagtatc aacataggcg
     6541 tccattgcaa gtttgactat ttcatacata ggaatatctt ttgcataact aagatcccga
     6601 atggttttta gtacgggagg atctacttga actggttttc tttctttcgc agtgtacttt
     6661 cgttccccta actcgacatt aatatcatct ttaattgaaa tatcttcagc accaattttc
     6721 ttcttatctt tgttcgttgg taataatgcc atttagttta atctcctttc caagaggtag
     6781 gatatgattg gccattgagt cagcatattt aggtgtataa tcaaatcctt caatatcacc
     6841 atgttgttca tagtattcaa ttctttcttc taattctgta aagatgtctg caaaaatagc
     6901 ccaccatctt cgatctacat aatcatttaa ttggatacca ttctcaccat acatttctaa
     6961 ccgatccgag cctttaacaa tgcttttaaa aatgtttgat tcaccatact tatcaattgt
     7021 tttttgatag tttgcgtgtt gagaggaacg tcgcactgag aaaagaacag gcaaaattcc
     7081 aatgatttga agatgagact cttcaaaatt cgtgacaatc ggaactaaaa ctttattaat
     7141 aaaatcttct gttccttcca ttgcgtaccg ttttaattct tgcattgcaa taatataatc
     7201 tgcagcagtt aagaatgcac gaaccacatt atctgttgat ggtgggcagt cgataaagat
     7261 ataatcgaaa ttttttctca attcttctaa aggtttaatg aaggccaatg atctcttacg
     7321 acgatcagga tatttttcgg acaagtattc attaagttct tcagatccag gagagccagc
     7381 cataatatat aaatgtggac ttacttgagt aatacctgaa acccagtccc cttttttgat
     7441 tgctgcagac atggatcgat caaagctagt aatttgatac gttgatccaa tgttggaagt
     7501 agtatttctt tgttggtcat aatcaattag caacacgtct ttttcaaaaa gttgactaga
     7561 aacaatcgct aataaatcat tgtctgtagt cttaccaatg ccgccttttc tacctgtaag
     7621 cattacaact tttcctagtt tatctgatgt tttaaatgca gtccgtaagt tttccatagt
     7681 tccctccaat ttcctatact aaatatattt agtatacttc atatacttaa tatattcgat
     7741 atatctaata tactccaaat tgataagaat tcagacttta taaggaatat agtggatata
     7801 ctaaatatat ttgctatatt cagtatatca gatatattca aaatgtcaaa atatatttgt
     7861 gcgttttgcg ttgacaattt agagtgaaaa gaggtaaact taattctata gaaaccacag
     7921 ataattcact atttacaaag tagcaaaagc agtggtactc tttaaacaga aaaattacat
     7981 aaaaaaaaga gacggaaata attgatttta gcagaatcaa ttatttctga atcacatggt
     8041 taggacatgt gttcacgctc gtctcaagaa tatgtaagta gctaccaact acttatatta
     8101 aaagttgatc ggataccttt tccgattgcc tttattctac caaaaaaagg cgagcaactc
     8161 aacagaagaa cgtttattta gtgtacttaa attaaatatt cttaaacact gaagagagaa
     8221 cacatactat ggctgagatt aaagctaaac tgtgttctct ttttgtttga gaaaggacgt
     8281 tacaatcgat gttgagcgaa atttattcag ctattcttaa aaacggctta cgtacataca
     8341 aatatcgaaa cagcaccatg aaacctgcag gtcatattga ttccagtagg agtggtgcta
     8401 tctttgcgta ccgtagcaag caattaatga atgttgggcg tggtatggtc attacttcgg
     8461 aagaagctat tttagagaac gaaaagaaac taacgcattg gacacctaat acctatcgct
     8521 ttggtactta tgcggatgat tatcgaacag tggttaaagg tcattctgag aaaaacttaa
     8581 gtcaaatcaa cacatttgta gttgatatcg attcaaaaga gaaccatcaa ggcgaaatta
     8641 ttttagcctg tttagatcaa gtgggctaca tgccaacgct aattttagaa tcagatcatg
     8701 gttatcaagt ttattttgta ctaaagacac caggctatgt cacaaagaaa agcaatttca
     8761 aggtgatcga tgtagcaaaa aaaatttcaa aaacaattcg tctacagttg gctgaaaaat
     8821 tgtccggagt ggatctagga tgtaaccact tcggaattgc tcgattccca caagaaaata
     8881 atattgtttt taaagaaatg aactatcagt attcttttgc tgactggatt caatggtcga
     8941 tgaagcttga atcagatcaa aaaacaaaag aagatcgaga acgaaaacta attgtctttc
     9001 ctgagaaaaa agaaattcgt caagtagatg aaccgtggtt cgatatgtta cttcataaag
     9061 caaacatcgt cggcggagaa ggacgtcttg gtcgaaataa tgtgattttc acgctttctt
     9121 tagcttatta ctcttcaggt tatgcattgg atacttgcga atacaatatg ttcacattca
     9181 acgaacggtt acaggaaccg ctatctgaag cagaattagt aaagattgta cgtagtgctt
     9241 attctggtaa ttatcaagca gcaagcagag aattcattat tgaattgtgc cagcaatggg
     9301 tttcaccaac cttaaaaaat aatgatctgt tcattcaacg acgtggctgg tggaaattta
     9361 aaaagccacg agatcaaaga aaatatagtc ataaaaatga atggaaagaa gatctattgg
     9421 cttatctaag cgaaaaaagt cttgctagtg agccttattt gaacctgtca aaaaaagaat
     9481 tggcttcaca actaacgatg cccaagcgaa cacttgataa gatcttaaat gagttacgag
     9541 aggagaataa agtcttctac aaggtaacac gaggaagaaa tggcggaatg atcattgctt
     9601 cagtcaaaac gttgttcgcg agggttattc aactaagtaa agaaaagaga ctagattatt
     9661 caacaaggat cacagaggta tttggactca acgagagctt agtagaagag acatttagac
     9721 aattatcaac ccccttgaac cctcttaaag aagtgaatct ttttgaagta gatacaggtt
     9781 gaaaaataaa aggtgcaaat tgccttatac aatatatcta tgatacttct gtaggtgttg
     9841 ctccctttgc ctagctacgt gtaggtggta tacttataac tgcgtatgca gtcttatgta
     9901 tcatggagga agttgtatgt cgttaaaaaa ttatgtctat tcacatcctg ttaatgtgtt
     9961 tatcattggt cgtttgggat tatctgtgga agtgttctgt gagctttatg gttttaagca
    10021 ggggactttg tcttcttggg ttaccaggga aaaaacagtt gcttctttgc cgattgagtt
    10081 tcttcatggg ttgtccttag cttctgggga gactatggat caggtatatg attgtttgtg
    10141 tgtgttagag caggagtata ttgagtataa aatagctaac gagttaagaa aaaggaagaa
    10201 gtatatccag tagtagtttt tatttactta aaaaattggt tcattgagca acctatcgct
    10261 gctaaagtag caaaggaaaa cgttaaagga aagaatttag ggaagaaatc gaaatgaaat
    10321 cggacgactg gattgaacac acctggcttc ctctgaaaag aaatagcaaa cgaaagaaat
    10381 tttgggtatt gcaattatgg ccattaggaa aactttgtag ttacggggca cgacttattc
    10441 ttgatttaac cgtttactcg attggagtat ttggaacggc ttattacttg ataaatgatc
    10501 ccaataggat tgcagcatca gacattttta cagtgctaat gacgttgatt tttgtcatgc
    10561 tattgtctat ttttactcaa ttagtcatgc aatttaccag gcaaaaatta acagcaggaa
    10621 aacttttcaa aagcctattc gatttaattg ttgtaaatgc aattctagcg actttaataa
    10681 aacaaattga acaatctgga agaacaacaa aaggagtgaa ggatttttta ttgacgttta
    10741 ttcactttgt aaatggacac atgtatttgt ttgaagtggg tattattctc ttttttgtcg
    10801 ggtatgtatc cacgaaactt attaaacgtt caattgaaaa agaaattgaa attgacctga
    10861 ttccgacact tcttggttat gagtacaatg ttgattttgg aagatatgac gaattgatca
    10921 atacggatat cgttcacacg agtatccatg aatctactgt taagggcatc agatctattt
    10981 taaaaaatgg ccaggaaatg aaagcaatag atcgaagaaa agagatctac aatttttatg
    11041 aagtcgaagc aagcctacga tatggcatcg gaaaattgtg gttagatgga agtaatattc
    11101 gtcaaaacaa accatacatt ttttggaaca gtagtgattt agaacttcca atgaaagata
    11161 aataattatg gagaatcgtt tgaaaatgat tcctctatac aggattgtgc ttatagttgg
    11221 catggagtta aaaaccttaa agaaggagca gttattcaaa gtgaaagaac gtcataatca
    11281 gttactatgt agtaaaacgg gtacgatgaa cattgaatac cgaacagaat atttagaatt
    11341 aacgaatcaa actgattttt tgttgattcg aaagcaacaa gagcaagaaa aaaattaatg
    11401 gctacttata gccaattgat tgatgaatgg gaacaattca aggaatctaa aattccagaa
    11461 cgtctctaaa agcctttatt tgtaaagagc ataaggaaac gtgggaacac tttttaaaaa
    11521 aagtgttcca ataggctgtg cctattacgt ttctcaaaaa taaatgtggg aacaaaatat
    11581 ttaaaaatag gatagtgaaa ggatagtgaa ggatagtaaa aggagggtag taggatagca
    11641 aaaaggatag gctccttttc gctatccttt ttaaattgga ggaattaata tggaagtaag
    11701 aataagaaat gtggatgaga aaatcgtaag agaaattgat cgaagatgtg acgaa
//
LOCUS       DAFLVO010000082        11623 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.084, whole genome shotgun sequence.
ACCESSION   DAFLVO010000082 DAFLVO010000000
VERSION     DAFLVO010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11623
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.084"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(105..629)
                     /locus_tag="L1U99_002404"
     CDS             complement(105..629)
                     /locus_tag="L1U99_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1212925.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="L1U99_002405"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="L1U99_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBN1212926.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1218..2198)
                     /gene="pta"
                     /locus_tag="L1U99_002406"
     CDS             complement(1218..2198)
                     /gene="pta"
                     /locus_tag="L1U99_002406"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBN1212927.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2351..3031)
                     /locus_tag="L1U99_002407"
     CDS             complement(2351..3031)
                     /locus_tag="L1U99_002407"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBN1212928.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3157..4026
                     /locus_tag="L1U99_002408"
     CDS             3157..4026
                     /locus_tag="L1U99_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1212929.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4052..4567
                     /locus_tag="L1U99_002409"
     CDS             4052..4567
                     /locus_tag="L1U99_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212930.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4614..5207)
                     /locus_tag="L1U99_002410"
     CDS             complement(4614..5207)
                     /locus_tag="L1U99_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1212931.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5232..5411)
                     /locus_tag="L1U99_002411"
     CDS             complement(5232..5411)
                     /locus_tag="L1U99_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212932.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5488..5997)
                     /locus_tag="L1U99_002412"
     CDS             complement(5488..5997)
                     /locus_tag="L1U99_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212933.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6093..6473)
                     /locus_tag="L1U99_002413"
     CDS             complement(6093..6473)
                     /locus_tag="L1U99_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1212934.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6803..7552
                     /locus_tag="L1U99_002414"
     CDS             6803..7552
                     /locus_tag="L1U99_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HBN1212935.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(7736..9013)
                     /locus_tag="L1U99_002415"
     CDS             complement(7736..9013)
                     /locus_tag="L1U99_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212936.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="L1U99_002416"
     CDS             complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="L1U99_002416"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBN1212937.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(9935..10879)
                     /locus_tag="L1U99_002417"
     CDS             complement(9935..10879)
                     /locus_tag="L1U99_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBN1212938.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(10881..11567)
                     /locus_tag="L1U99_002418"
     CDS             complement(10881..11567)
                     /locus_tag="L1U99_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBN1212939.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
BASE COUNT         3316 a         2464 c         2045 g         3798 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     1201 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     1261 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     1321 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     1381 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     1441 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     1501 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     1561 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     1621 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     1681 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     1741 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     1801 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     1861 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     1921 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     1981 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     2041 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     2101 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     2161 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     2221 atatgtatta tcatacacta ttccagaaaa aaagaacagt ttattttatc tgtatcagtc
     2281 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     2341 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     2401 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     2461 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     2521 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     2581 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     2641 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     2701 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     2761 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     2821 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     2881 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     2941 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     3001 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     3061 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     3121 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     3181 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     3241 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     3301 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     3361 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     3421 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     3481 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     3541 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     3601 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
     3661 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
     3721 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
     3781 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
     3841 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
     3901 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
     3961 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
     4021 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
     4081 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
     4141 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
     4201 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
     4261 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
     4321 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
     4381 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
     4441 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
     4501 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
     4561 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
     4621 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
     4681 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
     4741 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
     4801 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
     4861 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
     4921 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
     4981 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
     5041 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
     5101 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
     5161 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
     5221 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
     5281 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
     5341 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
     5401 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
     5461 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
     5521 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
     5581 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
     5641 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
     5701 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
     5761 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
     5821 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
     5881 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
     5941 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
     6001 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
     6061 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
     6121 tctggatcaa agaaaaacgt catttttttt cctgtaaagg tatcttctct aatcggttct
     6181 gattcgatcc ctaaggactg caattctgca attgtttctt caatatcgtc tactttgaaa
     6241 gcaagatgac gcaagccaca agcttctgga tagtttggtc gttgtggcgc attagcaatt
     6301 ccaaaaatct ccaattcagc acttcctagt ttcagatcta atttatagtc atctcgttct
     6361 ttgcggtaat tttctctgat tacttcaaat cctaatttat taacataaaa atcacgtgat
     6421 ttctgataat ctgaaacaat gatggctata tgatggatcg ttgtaaggtt catatgagca
     6481 ctcctattct tcgtttaagc tcggatctat attaatctcc agttccattg taaatgtgtc
     6541 agattgaaaa aaatagctgt ttttcctttt tataagaaaa aaggcaaaaa aaacagaaag
     6601 taggtcctcc aagacactct tcctgttccc aatataataa atgaaagtaa gaaattatat
     6661 tttcaagaaa acaaacagaa aattatcata acacaaatta tttataattg aaagactagt
     6721 tttttttcaa gaaaagcata caatagattg tgttagtaaa tacagaacac actacattta
     6781 gtgtcttaag gagtcctcat acatgaagtc atattttcag tttttagctc atcagctaaa
     6841 aggctggccg caacaaaatt attatctttt ctttttcagt cttggctgcc aggtcatgac
     6901 tcttgtcaat agtcccatca cttggctgtc cgttattaca tttatcggta ccacgcttgg
     6961 tgtattgtgt attttatcca tcaatgcggc aaaatcagtc aacggtattt taggtatttt
     7021 gtctgcgatt tgttttatta tcgttgggtt ttcagcaaag aactatttaa gtatcggtga
     7081 acagattgct tatatgatca cattggatat ccccgtattg ttaagtaaag aatggaatca
     7141 taatatggct tcaaaaatcc gaaaattcac tggaaaaagc tggtttatcg caatcatcag
     7201 tactttcctt gtctatcttg tttcaggatt cctgattggt cgttatacag atgatcctcg
     7261 gccgtgggta gatgccattg ctttttctat tagcttgact gctggtatca tcagtttctt
     7321 gcgttacaac aaccaatatt actggtggtt agcttcaggg cttgctcaaa tggtcctttg
     7381 gtatatttca tttacgcatg gatctgcaag tttggcgatg ttcgtgaaca gctctgttta
     7441 cttgctgaat gatgtccttg catttaccgt ttcaccttgg tataaccaaa aagaacgtga
     7501 acgtatgcaa aaaatggaag aagaatacta caacgcacaa caacacgcat aaaaaaactg
     7561 agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg
     7621 aatcagaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt
     7681 cgtgaatttc ttcttatttc ttggagttaa acgcttctgt cccagcctct attttttata
     7741 gtaattcctt cagatacttt cttgcctcat cattgaaacg cagtgattct tctaacttct
     7801 gataatattc caacgcttgt ttctgagctt cagtaaaacg ataatgtttt cctttccatt
     7861 tgtcgattgt ctcttgcaca tttccagatt ggatatcttt cactactagt tgccattttt
     7921 cttttgagac tgtacggtct ttcttatcag cagattgtat agcttctcgt tctttacgca
     7981 atacttttaa aaaaccattt ctgactatcc gaggaatgct gtcgaagaac ccttctgtaa
     8041 aaccatagcg acaatattgc ttccaaataa atagatagat ttttggttgg atgaatcgtt
     8101 ggtttttcgc aaaatattcc atctgagcag tgacttctgg tgttcgttga cgttttgtct
     8161 ttctcaacac ggaaataaat gtttcaaaat aagcattagg atgtactggc acttcttcat
     8221 atacgatgga ttgccaatct ttacgtaaaa atgcgcgata gttgatcaag aattcttcta
     8281 catcctttac taattcttct gcaaagtcgt caaatagttc tttttttatc tgtcgctttt
     8341 ttgactgccc attgatgtgt tcacttattt tcttgatttc attttccaat gcttgataat
     8401 ccgctatgta aatcggcatt tctacttggc gaaattctgc gagccgctga gctaatttta
     8461 tatccggtaa atatggctgt ttcatccgac gattttggta caagacaaaa cagtattttt
     8521 gccatagtcc ttcaggaaaa tcgatattct tctgcttaag ccataataat tcgtctaagg
     8581 ccagatcaac ttttgtcatt ccctgatgga tcgaagctgc cactgtcgga gagacatgca
     8641 ggtgatcggc aaagtggttg atgcctagtt ttaggatctt tccggttttt ggcgatttaa
     8701 cgatgtattg cacttttaat tctctaccac actcacaata caatttttgc tggcttcgtt
     8761 ttgttcgaaa aaacggattg atcttgaagt cagaaaacac ccaatctgtt gcagctaaat
     8821 aatgttcttc cataaaacga gagctgatta gatatcggcg gtgcttatcg actagttccc
     8881 gctgtttttt cgttaatttt gcatagatct cccaacgttg actgcttgtg tattgtttag
     8941 aaattttgat gggatagctt ttgctgattt cttttggaaa ccattcttca aagacggatt
     9001 gccattcttc cacggctgtt tctttccttt ctaattacaa aaagctggct actaacataa
     9061 cgttagcaac cagccagtgt ttcttgctaa attagtgagt tgttccggca tttccggaaa
     9121 tatcttcttt attttctact gctgcttcaa ctgcataagt caaagaagaa gcaatgtctt
     9181 ctaaagacat agaaggcgta cccactggac gatcgatcac ttgatcgggt gagaatggca
     9241 cgtggatgaa cccacctcga attgccggga attgtgtttc gatcaaatga agcaaacgat
     9301 acatgatatc attgcagaca aatgttcctg ctgtataaga gatgtacgct ggtagaccat
     9361 gatcttgtac attttttgtc attgctttga ttggcaatga ggtaaagtaa gcggctggac
     9421 cgttttcttc taaagccgta tcgaatggct gatttccttc attatcaggg attcttgctt
     9481 ctgctagatt gattgcgaca cgttcgaacg agactgctga ccgcccacct gcttgtccga
     9541 cacagatcac gacatctggt tggtgctgtt ggatggcttc tttgactact tgactgcttt
     9601 tttcgaatac ggtcggtact tccactttga tgatttcagc accgctgatt tcatctggca
     9661 ttttttttac tgcttcatag gctggattca ctttgtcccc accaaatgga tcaaaacctg
     9721 ttactagtac tttcatctgt tgttcctccg tccgattgat ttaacatatg gttatctttt
     9781 atcataccat tttccttgaa cagcgtaaat aaaggaaaca atagtttaaa taacataaca
     9841 gatcaaactt aatatattct tataaaaaaa tagtgttcca ctacaatgtt agaagaggtt
     9901 gcgacaatta ttctgtcaca acccctctct tctattattt aaatagaatc atataagcaa
     9961 tttggaaaac tagcataaat aacgcaataa acaactggtt tttgatcact ccgtatttgt
    10021 ctttcatctc cagcatcgct acaggcacga tattgaagtt agcagccatc ggtgtcagca
    10081 gggtcccaca aaaaccgcaa gtcaatgcaa ccattcctat taacgctgga ttcgctccat
    10141 gactaaatac gaatggtgca ccgatcccaa ccgtcatcac ggtgatggcc gcaaatgcat
    10201 tccccatgat taccgtaaat atcaccatgc caagagcgta aatgatgatg ccgatgttca
    10261 catttccttc tggaacgatc gtacctactg cattggaaat cactgtccca actccagcgc
    10321 ttgtaaatac cgcacctaga gaagctaaaa gcattggcaa catgcttaac ggccctactg
    10381 tgcccagcat atctgctgca tcatctaaaa atgtacttgg tcgattatct cgagaaaaga
    10441 acatcaagat tagcatggct gcaaaaacac cgacgcccac gccgactaaa gcacctaaat
    10501 tggtaaatag agcaaacaag atcgcaaaga caccgatact caaagctgga ataaaaattt
    10561 tcattcctag tttgtctgac attttttcca tatattcttt tgatggaagc cggctttctc
    10621 ctttgctgac tttcttagca attgctggta tggtcatcgc aaagatcaag ccaccgttca
    10681 cgattgccgg aagccatctt cctcctgcaa taactacccc taagaccgtc cagaaaaagg
    10741 ctgacccata acgatgagga ttggttttat ctgttaaatt tcttactcca gtgtaaatca
    10801 atacgagtcc catcacgata taaaggatct ccagtaattt atcgcctaat aaaatatcag
    10861 gatttgtaaa aaagtccatc ttattgcccc tttcctggat aatatttctt cgctaatttc
    10921 ttttctttaa gatagaagta gacacttgcc acaactaaag ccgtgatagc cactggaact
    10981 tccactaaag caagctgtcc caatgttacg tcatatccta gatctttcag tgttgattgg
    11041 actagcaacg cccctgctcc tccgatgaat agtacttggc caaagaacca gcagacattt
    11101 tccatagctg aagccatacc ttttagttct tcttcatgct taggatggac ttctaaccct
    11161 tttgattcga tggtccccaa tgccatcggt aaaatgattg gacgaacaaa tccagcaact
    11221 ccaccaaaac tcacgttaaa agccgcaaag atcattcgaa agatcccata aatatctaca
    11281 atcataccag cagatacttt cttgaatcgc ttgatcaagg aagccgctga ttctttcaga
    11341 ccatttcttt caagcgttcc tgttgccaac ataatgatga taaaaatcgc catcccgcga
    11401 ttgtttacaa aacttgtacc taaaagttct aacattcctt gaatgccaag accgccagtc
    11461 aaagctgtaa caactaaagc aaccattacg atcaatatcg agtctaattt aaatgcaaac
    11521 ccgagaataa caatcaagac gcctaaaagg ctaagataat tttccatata ttttcctcca
    11581 taaaatgaca atattttttt aattataaag caaaacacat aaa
//
LOCUS       DAFLVO010000083        11052 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.085, whole genome shotgun sequence.
ACCESSION   DAFLVO010000083 DAFLVO010000000
VERSION     DAFLVO010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11052
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.085"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            123..938
                     /gene="thiD"
                     /locus_tag="L1U99_002419"
     CDS             123..938
                     /gene="thiD"
                     /locus_tag="L1U99_002419"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBN1212940.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(1267..2718)
                     /gene="cls"
                     /locus_tag="L1U99_002420"
     CDS             complement(1267..2718)
                     /gene="cls"
                     /locus_tag="L1U99_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBN1212941.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            3059..5725
                     /locus_tag="L1U99_002421"
     CDS             3059..5725
                     /locus_tag="L1U99_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBN1212942.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            6089..6841
                     /locus_tag="L1U99_002422"
     CDS             6089..6841
                     /locus_tag="L1U99_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1212943.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(6863..8017)
                     /locus_tag="L1U99_002423"
     CDS             complement(6863..8017)
                     /locus_tag="L1U99_002423"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HBN1212944.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            8202..10643
                     /locus_tag="L1U99_002424"
     CDS             8202..10643
                     /locus_tag="L1U99_002424"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HBN1212945.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(10800..>11052)
                     /locus_tag="L1U99_002425"
     CDS             complement(10800..>11052)
                     /locus_tag="L1U99_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1212946.1"
                     /translation="TEGFQETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVPHSNG
                     VTEGLNNKIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
BASE COUNT         3584 a         1970 c         2379 g         3119 t
ORIGIN      
        1 ataaatttga ttaccaagaa aaggtagtgg tatatttact gagggatact ttgaaaaaca
       61 tatgatagaa acagtaacag tattatgaaa aatcttttta taaaaatgga ggaatcgatt
      121 tgatggaaga tcagtatgta caagcaatga cgatcgcagg atcagatagc gatggaagcg
      181 cagggatgca agcagatatg catacattct ttacaagaaa tgtttacggt gtttctgtca
      241 tgaccgcatg tgttgcaggt aattcttacg gaatcggagc aagtgtgaca ttgccaacag
      301 attttatcga caaagaattt gaactgattg cgaaggactt tcaaatacgt gcagctaaaa
      361 caggtatgct agcagattca aagttgattg agacagttgt aaaaaattac caaaaatatg
      421 attttggacc attagtcgtg gatcccgtaa tcgtaacgaa acatggaaat cttttactag
      481 aagaatctgc tttgcaaagc ttgaaagaaa agcttgtccc tttggccgaa gtactgacac
      541 ctaattttta tgaagcagaa aagctgactg gacggacatt agcagctgaa gaagattttg
      601 tgcaagcagc aaaagaactg caagatatgg gtgcaaaaaa cgttatgatc aaaggacatc
      661 atgctaaaaa tgcgcagcaa gaaacagtca atgactacgt attgttcgaa tcaggaaaat
      721 cattttggtt aaatgcacca ttttatccta ccgaccggat caacggaact ggcgattcgc
      781 tatctgcatg tattgcagct gagttagcga aaggaaaaac agttgaacaa gcgatccgat
      841 tggcaaaaga ctatgtaaac cgtgcaattc gtgaagaaat aaatgtaggg cacaaatatg
      901 gccccatcaa tcattgggca gctggtgaat tagagtaaaa gaaagaagtt gtgaaaaagt
      961 tgccctgcat caagtaataa gaacagccaa gtaaaaacag cttcttatgt ttttaacttg
     1021 gttggactta ttaccgcaga tgcaagcttt tgaacaccgt ttaagaaaga ggtcgtgagc
     1081 ctgccgtcca gctccgagtc acaaggaaca agttcaaaaa acagcttctc atgtttgttg
     1141 aatattgtga cttgtgaccg aggagttggc aggagaacac cgtttgttcg gaagaaggga
     1201 ctgtgacaag atttttgtca cagtcccttt aatcttagta tatttttctc tacttgaata
     1261 aaaaaattat aggattggag aaaataatcg agaaatttgt tgcttgaata atagccagtt
     1321 agacatttcc ttgactgttt cagttgtcat ggatgaacaa tgtgtctcat cttctttgaa
     1381 ctgagtagca agttcttcta aaaactcagg atcgtaaatg acagcacttg tttcaaaatt
     1441 caatcggtag ctacgaatat cttgatttgc tgaacctacc atgcagattt catcatccat
     1501 tatcaatgtt tttgcatgga ggaagccgtt ctcatagaca aggatttgta cattttcctt
     1561 gatcagctgc cgagcataat attgtgttgc tcgataaata aaaggatgat ccggtttgtt
     1621 gggaatcatg attttcacat ctacaccaga ggcagttgcg atttttaaag cagcaatgac
     1681 actttcatca ggaacaaggt aaggtgtctg tatccaaaca cgttttttag cagaagtaat
     1741 caatttgata aatgaaagct tgatttgttc cctttcgtta ttcggtccgc ttgaaacaag
     1801 ctggatggat gtatcagcaa gcttagattc atctcgatct gcttttttaa agaaataatt
     1861 caaatgatag ccgacctttt tttcttcagg taccgagacg ttccagtctg ttaagaagcg
     1921 aagctggagc aaagaagaag cggcaccgaa aatccgtata tgcgtatcgc gccaatagcc
     1981 gaattttttt gttgtattta catattgatt ggcaatattg aaaccaccgg tataactaat
     2041 ctttccatcg atcacaacga tttttcggtg atcatggtaa ttcaatcgga aacgaagtaa
     2101 tgccctttgt gaggtaacaa atgtatggac atgtccacca tttttgatta gacgattgaa
     2161 atcttttgct tttgtgccat gagagccaaa tgcatcatat aatattcgaa cttccacgcc
     2221 ttctgcggct ttttcttcta aaacatgtaa gacttgctgg ccgatattat ctgtcacaaa
     2281 tgcgtaatat tcgatatgga tcgaatgttt ggcttttttt agatcttgaa gcagtgaatc
     2341 caatttctct tgtccgtctg tgagaagagt gacagaattc attcttgtca gcggcatacg
     2401 atttaatgaa gagaagaagt caacaaattg ctgtttgtct ttatcgccca tgtcaggatc
     2461 gtaatgttca atggtatctc ctctaaaaga ctgaaagttt tctaattctt tcaagtcact
     2521 ttgtcggaga tagaattttt tcttatccgt taatccacgt ccgaaaaata aatataatac
     2581 aaagcccacc ccaggaaggg caaacaatac taagagccat gcccaaatgg ctgctacatc
     2641 tcggggtttg atcaaaatag ccaccaaagc aataagtgca tttaatagat aaagggcggt
     2701 tataatacta gataccacaa aaatgttcct ccttacatac aataacatta gtatagcatg
     2761 atagaagaaa gaagcctacc aaggtgaata tacttttcac tcctttcatg aaaatgtagg
     2821 taaatcgggc taaagtagtt gctttttgta ggttaataag gtaggatatt agtacagttg
     2881 aatatctcct taggggagta accggcaacg tttgttgcga taatatcaac agtaagttaa
     2941 ccaaatggtt ttctggtatt gtatgaaatg gtgagaccta agacaaatgc gtatttgtct
     3001 taggtctctt ttttttcaga caggactagg gccaagatca aaaaatgggg gatgaaattt
     3061 ggaaaacaag gaacaagcac aacaagcggt ctataaagaa acgatcgact cgttgatgca
     3121 gcaaacgcag agctcaaccg atggattgag caccacgcaa gcgaaggaaa aattagaaag
     3181 agatggcttg aaccagctaa aagaaaagcc gaagaagcca acttggaaat tgttcttaga
     3241 aactttcaaa gatgcaatgg ttatcgtatt gctgattgtc gcactgattc agatggtcat
     3301 gggtgactac atcgaattct tagttatttt tgcagtattg atgttgaatt ctataatcag
     3361 tgttgtccaa acaaaaaaag cagaaggttc tttagaagcg ttgaaaaacc tttcagcgcc
     3421 cgatgctcga gtgattcgtg atggtaagga aaaaacgatt ccggcaaacg aacttgtggt
     3481 aggagatatc gtgttgttag acgcaggcga ttatgtacct gctgatggac gtttactaga
     3541 tgcgggatca ttaaaagtag atgaaggtat gctgacagga gagtcgactt ctgcagaaaa
     3601 agaagtaacg gatatcacaa gtacggtacc aatcggagat cgtacaaata tggtattcag
     3661 tggaacgatc gtaacttacg gacgcggtaa attcttagtg acttcaactg ggaataatac
     3721 ggagatcgga caagttgctg gccttttgga atcaacaact gagcaagtca ctccgttaca
     3781 acgaggtctg gataaattca gtaaaaaact aagtttggct attttggcat tgtctttatt
     3841 gattttaggt atccaactgt ttcgtattta tcttggagaa ggtacaggag atatgactgc
     3901 agatatcgtc agcgcagtga tgtttgccgt agccgtagcc gtagctgcta ttccagaagc
     3961 attacagtct atcgtaacaa tcgtgttatc tttgggaacg aataaaatgg caaaacgtca
     4021 tgccattatt cggaagcttc cagcagttga aacacttggt tcgacaagta tcatctgtac
     4081 agataagact ggtacattga cacaaaacaa aatgacagtt gttgactact ttttaggtaa
     4141 tggcgatact ggggatttca caaatgaccc ttcaaaatgg acagctgacg aacgtcgctt
     4201 gatcgaaatc agtgttttag cgaatgatgc atcgatcagt gaagacggta ctaaattggg
     4261 cgaccctacg gaagtagcgt ttatcgactt tagtgaaaaa ttaaaccagc cttatcagga
     4321 aatccgaaac aactacccaa gacaagcaga acttcctttt gactcagatc gaaaattaat
     4381 gtctactgga cacacaattg ataacaaaaa ttacttgttt gttaaaggcg gaccagatat
     4441 cgtcttccaa cgcagtaaaa aagtattgct aaatggtgaa gtcgttccga tgacggatga
     4501 attgatgaaa aaattccaag agcaaaatga agctttttca acacgcgcat tacgtgtact
     4561 agcttttgct taccgtccac ttgataattt tgatttatca tttgaagatg aagacgattt
     4621 gatccttgtt ggtttgcttg ctatgatcga tcctccacgt gctgaagtga ctcaggcggt
     4681 aacagaagca agaagtgcag gaatcaaaac aatcatgatt actggtgacc acaaaacaac
     4741 agctgttgct atcgcaaaac aaatcgggat ttttgaagaa ggaaacctgg ctttgaccgg
     4801 gacggaacta gatgaattga cagaagatca actaaacgaa gttttagaaa aagtcactgt
     4861 ttatgcacgt gtttcacctg agaataaaat tcgtatcgtt cgtgcttggc aaaataaagg
     4921 tcatatctca gctatgacag gtgatggtgt aaatgacgca ccagcattga aacaagcaga
     4981 catcggaatt gctatgggaa cgggtacaga tgtggcaaaa gatgcagcag cgatggtatt
     5041 gacggatgat aactttgctt ctattgtcag cgcagtagaa gtaggacgta atgtgtttga
     5101 taatatcaag aaagctattt cttatctatt tgcaggaaat ttaggtgcga tcattgcgat
     5161 catctttgcc ttagttgctg actggtccaa tccatttaca gcattacaac tgttgttcat
     5221 caatttagtc aatgattcac tgccagcaat tgcattaggt acagaaaaag ctgaacctgc
     5281 tacgatgaac cgcccgccaa gagatccaaa ttcaggaatc tttacggaca aaacattgat
     5341 ttctgtaacg tatcgtggtg tgctgattgg gattgctgtt atctttgctc aatggcttgg
     5401 catgcagcat tcacctgaat tcggtgtagc catgtcattt tcaacattga tttggtgtcg
     5461 gacattgcaa acattcccag cacgttcaaa cacacaaaca gctatccaag cagggttctt
     5521 ctctaacaga agtgtcttac tagctgtagt tgtatgtagc gcgctttact gcttaacaat
     5581 gatcccagga ctgaaagaag tcttctctat cccatcagca tttggattga cagaagtctt
     5641 tacatgtatg ggaatcgcac ttgtgacaat tgttttgatg gaaatcacta aattgatcat
     5701 tgtacgagta caaggaaata aataaaacga atcaacgagg ttgtgagcct gccgtttaat
     5761 tctgagtcac aaggtgcaat ttcaacaaac agcttctcat gtttgttgaa tattgtgact
     5821 tgtgaccgaa gagttggcag gagaacaccg tttaaggaag aagttgtaaa atcagcattt
     5881 tgagctaata ctgagggtca tctgattgga cactgtttat tcggaaagag ggactttgac
     5941 acgactttgg tcacagtccc tttttttatt tatgatagac ggaaagccaa tcattttatt
     6001 attcatcaaa agagatagaa tagataaaag aggagaatga tttattccga aaagtgaaaa
     6061 catataacaa aaaattagag gaaatcaaat gaatgaaaaa gaatgggatg aatttgctga
     6121 agaatattat gaaatccagc aagaatcgca agtaactatt gctgaagatg taaaaaatta
     6181 tctgaaaacg gagaaagtcc tgcctgctga aacagcagca gacgttgctg gaggatctgg
     6241 cagatttctt tccttagcaa aagaaattaa tcgctatgat ttgatcgatt tttcttcagg
     6301 aatgctagaa aatgcaaaaa aagaagcaga aaaaaatgag ttgccaaatg tttcctttat
     6361 caaacagtcg ttagaagaat ttatccaatc aaatgagaca tatgaaatgg tttttacagc
     6421 agcaaatcca gcattggtac atcttattca attagaaaaa ttgatgaaaa agtcaagcaa
     6481 atggtgcgtg ataatcagag tagtggaatc aatcgatgat gttttttatc ctatcgaaaa
     6541 gcaactagga atgatagaag aagatcctaa tacatcgcca gttgtaatgg atcaatttga
     6601 aacatactta attgatgaag gattcaaagt gaagaaaaaa gattttactt attttacaca
     6661 ggaatcaatt actgaagaat tgatgaagct atactatgac gcgtacgcaa aagatcctgt
     6721 tgtgaccagg tacattcgca aactattcag tgaaaaacga gaaatcctta gtacgactaa
     6781 gctgacctat agactgctcc tttggtccgc agataaaaaa agaacctttc acgactcgtg
     6841 aagggttctt tttatgattt tattatattt tgtagtaacg aatatcattt tcgatctttg
     6901 taatcgaaaa aggtacatct gaagtatatt ctgcacattc tccgtgttca ggaagcgtct
     6961 cactgaaaat cgtttcatat tcgtcaacag tgatccgtgt tcgagaatct agcatctctt
     7021 gatgagattg tgcgaagaga tattcttgat agttttcttc cagataacct gtaaaaaatt
     7081 cacttactgc accagaaccg tagctgaata gaccgatgcg atctcctggc tgtagtgatt
     7141 tcgaattttc cagtagagaa gttagcccca ggtataatga accagtgtaa agattaccga
     7201 ttcgtcggct gtaacggatg ctttcttcat agcgagccat aagacgttcc tgattttctt
     7261 cgtctgtttg gtctaatacg ctttgcaatg ccttttttcc catcttagta tacggaatat
     7321 ggaaagcaat cgcctgataa tcttcgagtc ctcgacccga caattcttta tgtcgattcc
     7381 aaactttttg gaatgattcg atatacgtag aattagataa aggaccatca acaacaggaa
     7441 attcgctata atctggacgc cagaaatcat agatatcttc tgtcagaaat acgctgtcgt
     7501 cttcaatcga taaaatacgc gggttttgag tgatcatcat cgcaacagca ccgacacctt
     7561 gcgtcacttc accaccgctt gccaagctgt aacgagcaat atcacttgct atgactagta
     7621 cttttcgttc tggatgattt ttgacatatt ctttcgccat gtgcaaagct gcggtgccac
     7681 cgtagcaagc ctcttttact tcaaaagaac gagcaaaaga ttggattttc agtaaatggt
     7741 ggataattac cgcactcgct tttgaatgat caatcccgga ttctgttccg acgatgacca
     7801 tgtcgattag ctcacggtct ttttctgtta cgattttgct ggcagcattt gctcctagtg
     7861 taatgatgtc ttcatttgca cgattgactg ccatttggtc ttgaccaatc cctatatggt
     7921 attttgcagg atcatcccca cggctttctg ccaactctgt catatctaaa tataaattag
     7981 gaataaaaaa ggaaagacga tcaatcccta ttttcatttc aacacctctt tacttatgat
     8041 aaaaaactta ctttactaag gtatcataaa aagattaaaa gaaatataaa aaagagaata
     8101 tttaaggatt gttaaaattt aatcttagaa aaaaataact ggaacaagag ctatttgttt
     8161 ttacagcaaa gaatggtata tttttgtagg aggtggctta cttgaaagaa gtcgttatga
     8221 tagatgctgc aagaacgccg ataggaaagt atcgcggaag tttaagtcca tttactgcag
     8281 ttgaattagg cacacttgtg actaaaggat tattagataa aacaaaactg aaaaaagata
     8341 aaatcgatca agtaatattt ggaaatgtcc tgcaagctgg taatggtcaa aatgttgcca
     8401 gacagattgc tttgaacagc ggtctccctg tagatgtccc agcaatgacg atcaatgaag
     8461 tttgcggatc tggtatgaaa gcagtgatct tagcacgcca gctgatccaa ttaggtgaag
     8521 cagaacttgt gatagccggc ggaacagaga gtatgtctca agcacctatg ctgaaacagt
     8581 atcagtcaga aacaaatgaa tatggtgaac caatttccag tatggtcaac gacggattga
     8641 ctgacgcatt ttcaaatgca catatgggat taaccgcaga gaatgttgca acacaatttt
     8701 ctgtgagcag agaagagcag gatcgctatg ccttgtcgtc ccagttgaaa gcagcacatg
     8761 ctgtcgaagc cggtgtattt tctgaggaga tcatcccagt caagatttct gatgaagacg
     8821 tgttatctga ggatgaagca gttcgtggaa atagtacatt ggaaaaactg ggcacgttac
     8881 gtacagtatt ctcagaagaa ggaactgtaa cagcaggaaa tgcttccccg ttgaatgacg
     8941 gtgcctctgt ggtgatcctt gcatccaaag aatacgcaga aaataataat ctgccttatt
     9001 tagcaaccat caaagaagta gcggaggtcg gtattgaccc aagtatcatg ggaatcgctc
     9061 caatcaaagc cattcaaaaa ttgacagata gatcaggaat gaatttatca acaatcgatc
     9121 tttttgagat caatgaagca tttgcagctt cttctatcgt agttagccaa gaactgcagt
     9181 tagatgaaga aaaggtcaat atatatggag gagcaatcgc attaggccat ccaattggtg
     9241 caagcggtgc acgtatcttg actacattag cttacggatt gcttcgtgaa cagaagagat
     9301 acggtattgc ttcattatgt attggtggag gtttaggctt ggcagtcttg ttagaagcga
     9361 atatggagca aacacataag gatgtgcaaa aaaaaaagtt ttatcagctt acgccatctg
     9421 aacggcgcag tcaattaata gaaaaaaatg tattgacaca agaaactgcg ttgatttttc
     9481 aggaacaaac actttctgaa gagctctccg atcacatgat cgaaaaccaa gtgagtgaag
     9541 tggaaatccc aatggggatc gcgcagaatt ttcaaatcaa tggcaagaaa aaatggattc
     9601 cgatggcaac agaggaacca tctgtcattg cagctgcaag taatggtgca aaaatctgtg
     9661 gaaatatctg cgcagaaaca cctcagcggc tgatgcgagg gcaaatcgtt ctatcaggaa
     9721 aatcggagta tcaagcagtg atcaatgcag ttaatcatcg aaaagaagag ctgattcttt
     9781 gtgcaaatga aagttatcct tcaatcgtga aacgcggggg cggtgttcaa gatatctcta
     9841 ctcgggaatt catggggagt ttccatgcat acttatctat tgatttttta gtggatgtaa
     9901 aagatgcaat gggcgctaac atgatcaact cgattcttga gagtgtggca aacaagttac
     9961 gggagtggtt ccctgaagaa gagattctat tcagtatttt aagtaatttt gctacagaat
    10021 cattggcttc tgcctgttgt gaaatcccat tcgaacgctt agggagaaac aaagaaatcg
    10081 gtgaacaaat tgccaaaaaa atccaacagg caggggaata tgcgaagctt gacccttacc
    10141 gtgcagcaac gcacaacaaa gggatcatga atggtataga agctgtagtg gcagctacag
    10201 gaaatgatac acgtgcggtt agcgcttcga tccacgccta cgcggcaaga aatggattat
    10261 accaaggatt aacagactgg cagatcaaag gggataaact agttggaaaa ctaacggtgc
    10321 ctttggctgt tgccacagta ggcggagctt ccaatatcct gccaaaagca aaagcatctt
    10381 tagctatgtt agatattgat tcagccaagg aactagcaca agtaattgct gcagtagggt
    10441 tagctcaaaa cctggctgct ttgcgtgcat tagttacaga aggaatccaa aaaggccaca
    10501 tgggacttca agctcgttca ttagcgatct caattggggc tattggtgag gaaatcgagc
    10561 aagttgcgaa aaaattacgt gaagcagaaa agatgaacca gcagacagct atacaaatat
    10621 tggaaaaaat ccgggaaaaa taaaaaagca atatctttag aagaataaag caagatttac
    10681 agttatttta tttactgcag atcttgcttt tttggctctt cgtcaaattg tgttggcgaa
    10741 gacaaatttg aataaaactt agtccgatat gcggcgcgtt ctgtgcgccg catatttttt
    10801 tagttttcaa agatcagacc ttgttgtaaa tagatccgtg cccgaaagtt ataaaagttg
    10861 cgataaccaa acgcaattcg tttaatcagc ttgatcttgt tattcagccc ctcagtgacg
    10921 ccgtttgagt ggggcacctt aaaggcattt gaaatacccg attggtagcg atggaagatc
    10981 gtgaatttct ttttaaacga ctgaggtaac gtagatgaaa ttgttttaag ggtttcttga
    11041 aagccttccg ta
//
LOCUS       DAFLVO010000084        10848 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.086, whole genome shotgun sequence.
ACCESSION   DAFLVO010000084 DAFLVO010000000
VERSION     DAFLVO010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10848
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.086"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            33..656
                     /locus_tag="L1U99_002426"
     CDS             33..656
                     /locus_tag="L1U99_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212947.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1106..2155
                     /locus_tag="L1U99_002427"
     CDS             1106..2155
                     /locus_tag="L1U99_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1212948.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2152..3033
                     /locus_tag="L1U99_002428"
     CDS             2152..3033
                     /locus_tag="L1U99_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1212949.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3036..3806
                     /locus_tag="L1U99_002429"
     CDS             3036..3806
                     /locus_tag="L1U99_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1212950.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4085..4939
                     /gene="aroE"
                     /locus_tag="L1U99_002430"
     CDS             4085..4939
                     /gene="aroE"
                     /locus_tag="L1U99_002430"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBN1212951.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5117..6280
                     /locus_tag="L1U99_002431"
     CDS             5117..6280
                     /locus_tag="L1U99_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBN1212952.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6397..6807
                     /locus_tag="L1U99_002432"
     CDS             6397..6807
                     /locus_tag="L1U99_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1212953.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6981..9209
                     /gene="topB"
                     /locus_tag="L1U99_002433"
     CDS             6981..9209
                     /gene="topB"
                     /locus_tag="L1U99_002433"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBN1212954.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9380..9664
                     /locus_tag="L1U99_002434"
     CDS             9380..9664
                     /locus_tag="L1U99_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212955.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9824..10060
                     /locus_tag="L1U99_002435"
     CDS             9824..10060
                     /locus_tag="L1U99_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBN1212956.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10057..10455
                     /locus_tag="L1U99_002436"
     CDS             10057..10455
                     /locus_tag="L1U99_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBN1212957.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT         3792 a         1798 c         2270 g         2988 t
ORIGIN      
        1 aataaaaaat aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat
       61 cgagagtaca agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt
      121 attttcgacg tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt
      181 tattgccgga aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa
      241 ccagcaaatt gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg
      301 cgatatcggt gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt
      361 ttaatgatcc tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt
      421 atgatgtaca tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt
      481 tctttgatgg aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt
      541 ttgataagga gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag
      601 aagaagaatt ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca
      661 ttggcgcgat gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg
      721 tttgatcttc aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt
      781 cgattagact taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt
      841 atttcagcag aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg
      901 agactttccc atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga
      961 catgaacatt gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga
     1021 ccgctttggc cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa
     1081 agattgactt tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat
     1141 tattttagtt tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag
     1201 tacttcgacg aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca
     1261 tccggcatta gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa
     1321 agaaggagaa aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc
     1381 cacaatgagt caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc
     1441 tgccgctcaa tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac
     1501 ggatcctgtg ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg
     1561 tgtttctgat cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa
     1621 tgcaaaaaaa gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc
     1681 acaagcagaa gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc
     1741 cactaatgag attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt
     1801 tccattagat aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc
     1861 aaatatcccc gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat
     1921 cgggatcaat caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag
     1981 tggaaaagaa aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat
     2041 caatcaatct caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc
     2101 caaaatcatt acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta
     2161 tcagctattt cacaaggcat gctttgggca atattaggat tagggatttt catgacttat
     2221 cggatcttag actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc
     2281 tgtgtgacag ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt
     2341 gctggcatga tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt
     2401 attttagcag ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga
     2461 acaccaaatc tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg
     2521 ttacctgatt actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct
     2581 gtactgctat tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac
     2641 gaaacgatgg ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact
     2701 ttgtcgaacg gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca
     2761 gatgtaaata aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa
     2821 gtgatcttcc aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc
     2881 atttatcagc tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag
     2941 ttgttctccg ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg
     3001 aacttaaaaa cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa
     3061 atggcagaaa agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta
     3121 accttacaat cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa
     3181 gcacactgtt caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta
     3241 aagatcagct gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt
     3301 tccaagaccc caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg
     3361 cacaaaaaag aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag
     3421 attttttcag actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag
     3481 cgggtgaatt atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag
     3541 ctcctgagtt actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag
     3601 cattaatgcg attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca
     3661 cgcatcgaat ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga
     3721 aaatcgttca agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc
     3781 agttctttga agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact
     3841 tgaaaactca ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa
     3901 catatttggg tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt
     3961 ctttgctctg acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc
     4021 gtactttttc gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa
     4081 taagatgatt tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag
     4141 tttatcccca ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt
     4201 agctttccaa gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga
     4261 tatgttaggt gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga
     4321 ggtaagccag gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg
     4381 tttgattggc tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat
     4441 ttcgatcaaa aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac
     4501 tgttcaagct gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac
     4561 attcgctcaa gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa
     4621 agttcgtgac tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct
     4681 agtcaatgca acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat
     4741 aagcatgatg catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg
     4801 tttattaaaa gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat
     4861 ctaccaagga gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat
     4921 tgaaaagctg tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg
     4981 gtctcaagaa aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat
     5041 tatcaaaaaa tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa
     5101 acgaggagga accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa
     5161 acctctgaag cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat
     5221 ggaaaatgag gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt
     5281 gaaccaatac gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa
     5341 taaaaaattt ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc
     5401 gtggaaaaaa atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt
     5461 ttttattggt aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac
     5521 ctttcatggg caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac
     5581 acgcggagaa gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc
     5641 ccataagccg aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg
     5701 acaaaataag atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt
     5761 agtagaaaat tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga
     5821 aaaagtgatc gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa
     5881 tctggatggt gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca
     5941 gtacgcacgt ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca
     6001 agtaatgaac gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta
     6061 tgcagctggt aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa
     6121 aaacctcttt tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga
     6181 cggttcgtgg aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca
     6241 aatgaatcaa tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag
     6301 aagctgcgca aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc
     6361 ttatggtaga tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa
     6421 aatgagtcgc gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt
     6481 atcaccacat acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa
     6541 aatctaatca cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg
     6601 ccagaaggaa ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca
     6661 agaaatgaag aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag
     6721 atgccactgg atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc
     6781 atcaactggc agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa
     6841 gcagcaaacg gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt
     6901 atcttttttt tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat
     6961 taagtaacgg aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa
     7021 aagcctatgc cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg
     7081 atccattgtt tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg
     7141 ttgctccagg agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt
     7201 tcccagaaac cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa
     7261 aacgagaatt gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg
     7321 aagccatcgc gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt
     7381 tacgtttatg gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc
     7441 aacctggaaa gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt
     7501 ggctgattgg aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg
     7561 atggcagttt ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc
     7621 aagaagaaat caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga
     7681 caaacaaagg gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag
     7741 agttaacgaa ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc
     7801 ttgaagttac gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt
     7861 tgcagacaaa gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc
     7921 aaggattgta cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag
     7981 aaaatgagca tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag
     8041 aagaagtaca gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc
     8101 aagaacatca tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc
     8161 tttccaaatt acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg
     8221 ctgcagatta tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa
     8281 aaagcatcgg aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa
     8341 aaaagaaaga agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac
     8401 tgaaaagtat ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca
     8461 cagcaatgaa aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag
     8521 aagtagaagg aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga
     8581 agcattacat cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt
     8641 gtaaggcagt agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag
     8701 ggtacttgag aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca
     8761 aaaaattcat cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt
     8821 cagatgagat tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag
     8881 gaagatgtcc aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct
     8941 tgaatccgga atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa
     9001 cgaatctcag agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg
     9061 gtaaaaaagg gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt
     9121 cttttccatg gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa
     9181 gaaaaaataa tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt
     9241 ccgaaaagtg agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa
     9301 cgttggggta ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca
     9361 ttcattttta aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct
     9421 aaagtatcct gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc
     9481 accaacgttg attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca
     9541 taaaacgaca agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc
     9601 ggctatgatc attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg
     9661 ttaagaatac gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt
     9721 tcgtaagaaa aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa
     9781 tgtacttact atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa
     9841 gtataaaatt agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga
     9901 attcatgggt gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt
     9961 acgaatgatc aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa
    10021 tcaatatgaa gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa
    10081 attatcaaaa tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta
    10141 aaagatgcaa atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa
    10201 gaactctatc ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa
    10261 catccttttc ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa
    10321 ttgaataatt gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt
    10381 accactagtt cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa
    10441 accgcaataa aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa
    10501 ggaatatgct gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga
    10561 aaatatggat taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg
    10621 aaatagtggt ttagaactag tgggctgatt ttttatatat tttagtttac ataatatata
    10681 ttatacaaag tagatttaaa aaatgataaa cctctctcga acggtttttt atcaaaaatc
    10741 gtcatttttc catcaaaatc tgcttatgca aaattataaa aaaattttgc agtttttctt
    10801 actttttttg tcgtttaatt gaatgataaa aaccagtttc tttattca
//
LOCUS       DAFLVO010000085        10682 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.087, whole genome shotgun sequence.
ACCESSION   DAFLVO010000085 DAFLVO010000000
VERSION     DAFLVO010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.087"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            5..2377
                     /locus_tag="L1U99_002437"
     CDS             5..2377
                     /locus_tag="L1U99_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212958.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEEYVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESAFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     RPTDSMKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2438..3898
                     /locus_tag="L1U99_002438"
     CDS             2438..3898
                     /locus_tag="L1U99_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBN1212959.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3909..6113
                     /gene="topB"
                     /locus_tag="L1U99_002439"
     CDS             3909..6113
                     /gene="topB"
                     /locus_tag="L1U99_002439"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBN1212960.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6129..6278
                     /locus_tag="L1U99_002440"
     CDS             6129..6278
                     /locus_tag="L1U99_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212961.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6353..6946
                     /locus_tag="L1U99_002441"
     CDS             6353..6946
                     /locus_tag="L1U99_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBN1212962.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6959..7858
                     /locus_tag="L1U99_002442"
     CDS             6959..7858
                     /locus_tag="L1U99_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBN1212963.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7861..8358
                     /gene="ssb"
                     /locus_tag="L1U99_002443"
     CDS             7861..8358
                     /gene="ssb"
                     /locus_tag="L1U99_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBN1212964.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            8724..8984
                     /locus_tag="L1U99_002444"
     CDS             8724..8984
                     /locus_tag="L1U99_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212965.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9429..9635
                     /locus_tag="L1U99_002445"
     CDS             9429..9635
                     /locus_tag="L1U99_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBN1212966.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGQRAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9683..9886
                     /locus_tag="L1U99_002446"
     CDS             9683..9886
                     /locus_tag="L1U99_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212967.1"
                     /translation="MVDKEVISEKVAEALLIPRYWTIETPLVEDAPTMLFEDLVKIAG
                     YELHYQENMETYENEYWLTKLEN"
     gene            9902..10339
                     /locus_tag="L1U99_002447"
     CDS             9902..10339
                     /locus_tag="L1U99_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212968.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            10332..>10682
                     /locus_tag="L1U99_002448"
     CDS             10332..>10682
                     /locus_tag="L1U99_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212969.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKH"
BASE COUNT         4033 a         1789 c         2240 g         2620 t
ORIGIN      
        1 gaacatggca gaagaaaaag aaccactaga caatagtcgt ttgggaaaat ccaaaagaaa
       61 actagtacga ttgcaaaatg aattaaacga acaaattgaa aagatgtttg aacaccaaaa
      121 aatgacgaac ggtcaaccaa tgaacgacaa gaggaatggc cgttcatggt ttaaccagca
      181 agaacgaatc gaaaataaag tccaaagtct gagagaagag atcaagcaac aagaagaata
      241 cgtggaaaag cttgaaagac aagaagagct aaaggaaatg ggctataaca agtacggcgg
      301 actggatatg acgatcgata atattccaag aatcaaagaa gaaatcgaac gctttgaaaa
      361 aggtgaatcg gctttttcag ccgccacgat ccgaaaatac caacggaagt tggaaacatt
      421 agaacagctg aaagaaaaat cagaaaaagg aaaagaaaat atcctccctg aagtacaagc
      481 gatcattgac agcggacgag tgacgcaatg gaaaaaaaat ccaaccattt attttttgaa
      541 aggctatcga aaagttgctt tagaactgaa tgaaaacggg ggatttgagg aatcaaaaaa
      601 ataccaagcc acgtcggaag aggaaaaagc agctgttcgt gaattacttg aagaggctag
      661 accaactgat tctatgaagg agaaagaaaa cgatcatttc tatcgagtag aattcaacga
      721 aaatgatcca gaaaaaggat tgaaaagtta tggtggggag atcgtaacat tcgaattgat
      781 cgatcaactc aaaacattgg ataaccaata cgccgcagaa gcaggttatt ataaattcta
      841 ttttgaggaa gtgaagaacg gagaagtagt cgatcagatc cgaatggatc taggggatgg
      901 cgtcaacagt aatcaaccaa tctatttaga gttagcaaaa ttgtgcgaac aagtacctga
      961 gaaggaacaa aaacaatcgg tcaaaaatga acctgtttcg aaagaacaaa tgcagtcgaa
     1021 agaaacaaaa acaaaacaaa agggctatca aaaacgaacg gcagaagaga ttaaacaaga
     1081 agttaaatcc ctttcgcaac aggcactgga tgcggtgaaa aagcataccc attctcctga
     1141 agacgtcaaa gaacttttga actttatgtc tcgttttcca gaacgatcct ttagaaatca
     1201 attattgatt gaggaacaat ttccaggtgc aacggcttgt ttaggtcgtg ccgcgttgaa
     1261 aaaagaagga atctatatca aaaaagggga acaagggaac aagatctttg tcagaaaaac
     1321 ggtcaaaggg ttttatgaga aaggacgtgg ctttgttcga gaaacagaag ctacaccaga
     1381 agataaaaaa cgaatcgaaa gtggtcaaat cgaagtgatc aaaaaacctt actatacgat
     1441 tgaaaaagtg tttgatatca cacaaacaca gttaaaacct gaagactatc cgaaaatctt
     1501 tccgaaccgt gtctttgatt ttcaattgga taaaaaagga cagtcagaac ttcaagctgg
     1561 gattcaagcg gtagccaaca atattggaat acaaattcga gatatgacag aaagtgaagt
     1621 ctatcaaaga gaattaggac aagcacgtgg ggcgtatgtt cgtaacgaat ttactggcga
     1681 agaagaaatc gtcatgaata ctcgaaatac tcctacgcag catttagcta caagtattca
     1741 tgaattagcc catgcaagaa tgcacaaatt ttcagaatta gataccgcaa ctaaagaatt
     1801 gcaggcagaa atgacttctt atattgtgtg caaacatttt ggaatggaca cgtcggagaa
     1861 agctattcct tatattgcag catggacgaa gaatggtcag acgttggatg ataaggaagc
     1921 tgcggaacgt gggaaaatca tgaatgatgt cagccgtgtc gcaaatgaat tcattcaaac
     1981 catttctaat gaaatcaatc aatacagaga aagagaacca gagatccaac cagcagaagt
     2041 gaagcaggag cataaaaata ctttagaaac gccagagaat aagaatattg tgcccgttgg
     2101 ttcactttgg atcgacaaga aagacgggaa agtaatggaa gaagatacgg gtcgaacgtt
     2161 acatttgaag gatgcggcgt ttattgaaga tccgcagcat aatcaagtaa ttttaaaagg
     2221 aaaaagttat ggaaaagaga tccaaacggc gttaccttca gaagaatttg cgctaggaaa
     2281 tccattccga ttttcacttg agacagtgtc agaagtggca aaacgaaaaa atgaaatcta
     2341 ttatgaacaa caattgtcac aaaaagaacg tgtataaaac aagtaaaaaa gactatctga
     2401 aaaacggata gtcttttttc ttttgggagg ttttaaaatg accgagaaaa aaatgagtct
     2461 tattgatcga tgtaaacaga tcgatatagt ggattttgct cgaaacaatg gaatggctgt
     2521 agtcaataaa ggacgagatt atcgcttaga agaccatgat tcatttgttt ttgatcgaag
     2581 aaaacaacgt ttttattgga acagtcaaaa tattagtggc gacattattg aattagctaa
     2641 actttttttc atagacaaag agatccaaga ccctaagcaa caatttaaag cagccactga
     2701 ttttattcta aagaatgaag acaaaacaga acgagtggaa aatcttcatt ttgaaacaga
     2761 aaagtacaaa gatcaccccg ttgattatca accactcaca gaaaaaggaa ggaattatct
     2821 gaaggaagaa cgaaaactac cagagtggct gattgattat gcagaaaaag aagggttgat
     2881 tgccgaacta aagccaaaat atgaacggca aaatttctta gttcgagacg atcgtttaga
     2941 tcatgcggtc gcctttttat ggaaagatcc acagacaaaa gagacagtag gggcgagtta
     3001 tcaaggaacg ttcattgatt atgaacgttt tggtgagaga ggcacatata agcatataga
     3061 taaaaattcg acagcgaatc atggctttaa cctaaagatc ggtgacccta agcagataaa
     3121 attttttgag agtagtattg atttacttag ctatgctgca ctgaatcgtg atcagttaaa
     3181 cgatacgtgg ttagtctcta tggaagggtt aaaacaccat gtgatcagtc attattttgg
     3241 tgaggcagta tctgaattga gaaagaaaca agcctttcct caatccatcg agatttgtgt
     3301 ggataatgac cgtgcaggac atattttcta cgaaaaagaa caattaatgg gcgcagtcga
     3361 tccatttacg aatcagaaag tacgttgtga acgaggaatc gctaatgatt ggcaagtgcc
     3421 aaaagaatac aaaatcattt atgaagaagt cgcaaaagaa gaaaaggtca caccagaagc
     3481 tattatggcc atacacaaga cagaaaacaa tctgcaatta acgaaccaac tggtttccgc
     3541 tcacaaagta aatgcgtttt ttggccagca gctttctgtt aacgattcaa tagaagccat
     3601 taatttgaaa gatatttgta gagaagtcgc aaaagaatta aaagtttgtg aacgcgtgga
     3661 tggtacgtac gattttgatc gtttttatca agaaaaaggg gatattaatg cgcagattct
     3721 tttctcttat aaagcagaac aatactacaa aggctataaa aatcatgaac atgaatttgt
     3781 acctgaagta aaaaaggact ggaacgatca attgaagcat gagatccagc aacaagaaat
     3841 cagaaagcaa aaacgtgcca tgttgtttca acaaggcaga caacaagaaa gggagtgaaa
     3901 tcgtcatgat gaaaaccgtt attttagcag aaaagccgtc acaagcgaaa gcttatgccg
     3961 atagcttctc taaagccact cgaaaagacg ggtattttga aatccaagat cgattgtttc
     4021 ctggtgaaac tgtgatcacg tatggttttg gtcatttagt cgaattagat tcgcccgata
     4081 tgtacgatga aaattggaaa caatggtcat tagaacattt gcctattttc cctacacatt
     4141 atcactatca tgttcctaaa gataagaaaa agcaattcaa ggtggtgaaa cagcaacttc
     4201 aatcggccga caccattatt attgcgacag atagcgatcg tgaaggggaa ctgatcgctt
     4261 ggacgatcat tcaacaagta ggcgccgatc aaggaaaaac ctttaaaaga ctttggatca
     4321 actccttaga aaaagaagcc atttatcagg gattccagca gttacgagac gcaaaagaga
     4381 cctatccaaa atttgaagaa gcacaagcac gtcagatcgc cgattggtta attgggatga
     4441 acggtagccc actgtatagt ttactcttgc agcaaaaagg cataccagga agcttttcct
     4501 taggcagagt ccaaacccca acgctttaca tgatttatca attgcaggaa aagattagaa
     4561 atttcaagaa agaaccttat tttgaaggaa aatccgaagt aatcgctcaa aatggcgcat
     4621 ttgatgcgaa gcttgatccg aatgaaaccc aagcgacgca agaagcattt gaagattatt
     4681 taaaagaaaa gggggttcaa ttgggaaaac agccaggcat gattcgccaa gttgaaaccg
     4741 agaaaaaaag cgcggcaagt ccacgtcttt tttctctatc cagccttcag tctaaaatga
     4801 atcagctcat gaaagctagt gccaaagaca ctttggaagc catgcaaggc ttgtatgaag
     4861 ggaaatatct aagctatccg cgaacggata ccccttacat tacggaaggg gaatatgcgt
     4921 atctgttgga tcacttagac gaatacaagc attttttgag ggctgaagaa atttcgactc
     4981 ctattcatac accgaatagt aggtacgtga acaacaagaa agtccaggaa cattacgcaa
     5041 tcattcctac aaaaacagtt atgacagaag cgacgtatga aagtctgaca cctttacaac
     5101 aagcgattta cgagcaagtt ttaaaaacga cagtggcgat gtttgcggaa aaatatacct
     5161 atgaagaaac aacgatcttg acgcaagtcc agcagcttca gttaaaggca atcggaaaag
     5221 taccgataga tctaggttgg aagaagttat ttggcaaaga gagcgacgga aaagagaagg
     5281 aagaagagcc gctacttcct aaagtgacaa aaggagaaat ggtgacggta gatctacaag
     5341 tccttgaaaa agaaaccaag ccaccacaac cttataccga aggtacgttg atcactgcga
     5401 tgaaaacagc tgggaaaacc gtggatagtg aagaagcgca atccatattg aaagaagtgg
     5461 aaggaatcgg tacagaagcg acacgggcga atattattga aaccttgaaa caaaaggaat
     5521 atatcaaggt agagaaaaat aagcttgtgg tgacgaataa aggggttttg ctttgccaag
     5581 ctgtggaaaa agagccgctg cttacgagtg ccgaaatgac cgccaaatgg gaaagctact
     5641 tgttaaagat tggagaacga aaaggaacac aaaccacttt tctagccaat atccaaaagt
     5701 ttgtctctca cttattggaa gtcgtcccag gacaaatcca atccattgat tttggatcga
     5761 cgttacaaga agtgaaagca gccagtgaaa agcaagaagc cgcgcgtcat ttaggaattt
     5821 gtccaaaatg ccaggaacaa gaagtcttac tctatcaaaa ggtggcagct tgtacgtctg
     5881 aagcctgtga ttttaaatta tggacaacga ttgccaaaaa gaaactcaca gcgacacagc
     5941 tgaaggagat tattcaaaat agccgaacaa gccaaccagt gaaagggtta aaaggtcaga
     6001 agggttcgtt tgaagcaacg attgttttaa aagaagactt cactacaggc tttgaatttt
     6061 ctgaaaagaa aaaaacgaac ttcaagaaaa gaacacgacg cacgacaaaa taatggaggg
     6121 ttaatcttat gcgtaataca acacacaaac aacaagaaat cgaaaatcaa aaagccaaaa
     6181 ttcgttcaga acaagagaaa ttacgtgcca gtaaaagaag acttcagcaa ttaaagaacc
     6241 agcaacggat tcaaaaagaa atcgaattag atcgatagac attaaccttg ttacaaatac
     6301 actatcatga tatatttaat gtagtgtatt tgtaacaaaa ggggggaagt aaatgcaaga
     6361 gaaactgaaa gaattgttgg ctattcgcga tggaaattta tctatgaagg aagccagaaa
     6421 attaggaatc gcagcaacca ctgtacaaag attggtgaat caaggaaaat tgatcaaagt
     6481 tgatcgtggt tattatgtag aggatggtca tggaatagat gatttatttt ggcttcagca
     6541 acgtttttcc aggggaatct tctctcatga aacgacttta gatatttacc agctttctac
     6601 gaatatgccg aaattcattc acttaacttt tccccatgga tataacgttg atcgttcaat
     6661 tacaaaagag cagcagttac aatttcattt cgtgaagaaa gaagtttatg aactaggaaa
     6721 agtagaggga acttcctttc aaggaaatcc tattactatg tatgataaag agcgtacact
     6781 ttgtgatatt tggaatccga gatatgaaat tgaatatgaa atgaaattag aagcattaaa
     6841 agagtacatg gaagacccat tgagagatcc aagtaaatta agagattaca tgacaaaact
     6901 acatgtagaa aaagaaatga aataccacat gcaaagctta tattgatgga ggaaaaagat
     6961 gacaccgaca caatttgcag caaaaacaag aaatttagca aagaggacag gattaaatgc
     7021 acagttagta caacggcatt ttatgatgga tcgtttaatt gaacaaattt ctgaatctaa
     7081 gtataaaaat gatttcattt tgaaaggtgg ctttttatta ggatcaaaat atggaatcga
     7141 tagaaggacg acaattgata tcgacacgac atttagaaat agcaaattaa ctgaagaaaa
     7201 attgaagagt atttttaatg atttaactag gaaacccacg aaagaaggta ttgttttctc
     7261 tattcaagga atgaaggaaa caagagaagc cgatttttat cctggatttc aaattaaatt
     7321 ggtggctaat ttagagaaag tacgtgtgcc atttaaaatg gacgtgacaa caggagattc
     7381 tatttatcct gaagtagata cacactatca ccaattaatg tttgaagata aaaaggtgga
     7441 gattccagct tatccaacag cacaaattat tgcagaaaag ctaagtgcta cgttcagctt
     7501 tggcacagat aattcgagag caaaagatta ctacgactta tttaccattc cgaaactaga
     7561 aaatatcgat acgaaagagt tatacaaaag tgttcgaaat acatttacaa aacgtgggga
     7621 tacaaaaccg ttgtcctttt attatgaaag agaaatggat aagatcatag gaaatgacta
     7681 tttggaaaag cagtgggaaa aatatcgctc agttaacacg tttgcgaatt ccatttcatt
     7741 tacagataca gtcaacgaaa ttgatcacct aatgaaaagt gtgatcaaaa ttgaaaatca
     7801 agaaagaaaa cggcagttta aaagatcaca acaaatgaat caagaaatgg agagataaag
     7861 atgatcaata atgtaacttt agtaggacgc ttaaccaaag atccagattt acgttatacc
     7921 gcgagtggta ctgcagtagc gacttttacc ctagctgtca accgaaattt cacgaatcaa
     7981 aacggcaatc gagaagctga ttttattaac tgtgtgattt ggcgcaaacc agcagaaaca
     8041 atggtgacat tagctaaaaa aggtagcttg attggtgtag ttgggcggat tcaaacgcgg
     8101 acttatgaca accagcaagg acaacgtgtg tatgtgacag aagttgtggc cgataatttc
     8161 caactattag aaagcaaagc agcgacagaa agccgtgcgc acgctgatca atcgtccacc
     8221 agtccaagca ccaccacttt tgaacaacgg gatacagcga cgcctaataa caatggattg
     8281 aacgctttac agaatccatt tgggaatcca tttggtggac aatcaatcga tattagcgat
     8341 gatgatctac cgttctaagt agcattttct attggttgca tttgctacgg tttatgttat
     8401 aatttagtca acaaaaagaa ttttcaatct ataaccaaaa accactagct ggcgggctag
     8461 tggttttctt ttacgtttct attataagaa ttaacgggta ggcttactgt ctttcttggc
     8521 aaatttacaa tcaagccatt tgcagatata gtgcgcggct acttctgcca tgattgcaaa
     8581 aacaaaatca aaaagaattt tcaaacctat aacctcctcc ccttgccaga ttaggccggg
     8641 gtagcagaca gcaagactat tatagcataa ttgaaatatc caaatgattg gatttttgct
     8701 ataattttag cgaggtgatt gtgatgaaca aatatgttgg tttgcttgat aaaatccgag
     8761 taataaaaac gcaaccgtta ttggttcgct ttactttaca aacgattcat gaatcgatta
     8821 attgtgtagt tgcagatatt gaaattatcg ataaattgct aattatggat gatggaaaat
     8881 acaatattgc cgtcacaggt cacttcaata aacgaaatca gctagttatt gctagcatgt
     8941 atgttagaaa tcccgatcat tttacgcgat cgatgggcat ataaaaaaag aagagttgca
     9001 atcctaatgt aggactgcag ctctttttgt tttacataga aacaagaaaa atgaaaaggc
     9061 ctttttagga aggcgcgagc gccttctcaa ttgaaaaacc tctctcactc caaccgccac
     9121 cgccgttcga gaagaaagga agtgaacgtt gcacgttcac taagataaag ggtcttgcaa
     9181 agcaagacaa aatagaaaaa acttcctctc accaaaaggt tcgttcctgt tcgttatctc
     9241 tttattgatt tgccagaccg gcaacaagtt gccttttatc accaaaaagc gacaaggaca
     9301 agggtaaatg gcacgctgcg cgcccttgtc cttgtcgctt ttcgttgatt cattctggcc
     9361 aacaaatcaa taaagaaaga actaacgaaa ggaagtaaaa cctttcctaa gaggaggcag
     9421 aatcaatcat gcgaaagaaa tttgattatt ggggtgttcc cttcagcgaa ttattcccaa
     9481 actatcatgc accacatact gtcgaatgcg attgtggaca aagagcgaaa tgtatcaaaa
     9541 gctatcgttt gtatcaatgt ccaacatgcg gaaaaaaata caccttgtct tatggcgatt
     9601 atattttgat tgatgagaaa ggaaagaaac gctgatgaaa acataacata aattattgac
     9661 tgtaaaagaa gtcgttcaaa ttttggtgga caaagaagtc atttctgaaa aagtagcaga
     9721 agctttactt attccgcggt actggacgat agaaacccct ttagtagagg atgcaccgac
     9781 tatgctattt gaagacctag tgaagattgc aggatatgaa ctgcattatc aagaaaacat
     9841 ggaaacttat gaaaacgaat attggttaac caaattagag aactaaaaag gagaaaaaaa
     9901 tatggctcaa aattactatg acgaatttgt caaattacct ttggataaaa tggcacaaaa
     9961 aatggaggat atgacattcc tataccatga gacacgtgtt ccaaaaaaac attataagga
    10021 aagattgtcg gtagctgtgg aagaaatgat tgaatcaggt gtcgaaatga atctcattgc
    10081 gacgtactat cgaacactgg aagaactgaa aaaacaaaat gcaaaatggt ttttccaagc
    10141 cttactatgc ttggaagtag gtgtcaaacc aagcactatt aaaccttctg aatatcaagc
    10201 tttagaacta acgtatggga aatttgtcga aacgaaaaaa gccaagactg tttcaagtga
    10261 atggttagat tattttgaaa atatcaataa gtatggcgcc tattacacca tgaaaaagga
    10321 ggacaacgaa aatgaataag gtgatttatc aactaacaac ggaagatgtg tcacactttt
    10381 taacaaacaa agaacatttg aatgaagtaa tcagacggat tcaaaaagac tttagttgta
    10441 tggaagaaat gaagtacttt attcaaagag tcgaagaaca attgtatttg gaaagtgaaa
    10501 cgagtcaaac gaaggtcaca gtcagcaata attatttaga cgtgtataaa catcgtcctg
    10561 aaacggtaaa aaaaggaacg gagcttctac gactagaaac agaaaaatac atcatgaatg
    10621 tttacctaga aaggagtgaa ctggtcgaaa actttgtcag ctgcacgatt tgcaggaaac
    10681 ac
//
LOCUS       DAFLVO010000086        10365 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.088, whole genome shotgun sequence.
ACCESSION   DAFLVO010000086 DAFLVO010000000
VERSION     DAFLVO010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10365
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.088"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            11..310
                     /locus_tag="L1U99_002449"
     CDS             11..310
                     /locus_tag="L1U99_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1212970.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            383..1744
                     /locus_tag="L1U99_002450"
     CDS             383..1744
                     /locus_tag="L1U99_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBN1212971.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1766..2026
                     /locus_tag="L1U99_002451"
     CDS             1766..2026
                     /locus_tag="L1U99_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212972.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2040..2792
                     /locus_tag="L1U99_002452"
     CDS             2040..2792
                     /locus_tag="L1U99_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBN1212973.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2886..3491)
                     /locus_tag="L1U99_002453"
     CDS             complement(2886..3491)
                     /locus_tag="L1U99_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1212974.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3544..4518)
                     /locus_tag="L1U99_002454"
     CDS             complement(3544..4518)
                     /locus_tag="L1U99_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HBN1212975.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4896..5615)
                     /locus_tag="L1U99_002455"
     CDS             complement(4896..5615)
                     /locus_tag="L1U99_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1212976.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5742..7013)
                     /gene="celB"
                     /locus_tag="L1U99_002456"
     CDS             complement(5742..7013)
                     /gene="celB"
                     /locus_tag="L1U99_002456"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBN1212977.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGIIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7166..8563
                     /locus_tag="L1U99_002457"
     CDS             7166..8563
                     /locus_tag="L1U99_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1212978.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8644..9084
                     /locus_tag="L1U99_002458"
     CDS             8644..9084
                     /locus_tag="L1U99_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBN1212979.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9232..9558
                     /locus_tag="L1U99_002459"
     CDS             9232..9558
                     /locus_tag="L1U99_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBN1212980.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9559..10308
                     /locus_tag="L1U99_002460"
     CDS             9559..10308
                     /locus_tag="L1U99_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212981.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
BASE COUNT         3289 a         1825 c         2151 g         3100 t
ORIGIN      
        1 ggaagaaaaa atgaaaaatc ggttaattgt cgcatgtgga agtggagtag caacgagtca
       61 gacaatcgct agtaagatcc aaagtatgtt agaagatgac ggcatcgcat ttcctgtaga
      121 agcagttgat tacaaatcga ttcaaaatga gcttctaact gctggaatct atgtgtatgt
      181 cgcacaacct gatgaggaag tacttgaaca agcaaaagat ttgggtattg aagtatttcc
      241 aggaattcca tttttaactg gaatgggtgt agaacctatt tatgacagta tcaaagagtt
      301 agtacagtaa aggaggattg ttggataaaa aagttggttc atagttttat ttactatatt
      361 tagaaagaaa gaaggtttat ttatggaagt tttccaaacc attatcaatt atgttttgaa
      421 cttaggatca gccatttttg ttcccctgat tattttgata cttggattgt tggcagggat
      481 gaaattaaaa aaagcattca tgtctgcttt gactttaggg attgctttta gcggaatgtc
      541 tatggtcatt ggctatatgt ctaacgcagt aagtccagca tcagaagcat tggctaaaaa
      601 tacgggaatc agtttgcctg cacttgatct tgggtggaca ggtgcagcaa gcatcacatg
      661 gtcgtggagt tatgctttta tattttttgc agtaacgatt ggggtcaatt ttgtactgtt
      721 actttttaat tggacgaaga cgttaaatgt tgatatgtgg aatgtttggg ggaaagcttt
      781 aactgcttat ttagtttatt atgtttccgg tagtttggct gcaggctttc ttactgcaat
      841 ggtccaagtt atattggaat taaagcttgg tgatatgttt caaaaacata tacaagatct
      901 cacagggatt ccattagtaa cagtgactca ttttatgaca tctgccgctg tcttgttgct
      961 gcctttcaat atgatcatgg ataaaattcc tgctttaaat aaacgagcgg atacgaatgc
     1021 attgaagaag aaaattggga tcttctctga aaactctgta atgggattca ttattggatt
     1081 ggggcttggc tttgctgctg cgtatggcgt ttcaggttct cttaatctag cgatccaaac
     1141 agctacagca ttaagtttgt ttcctatgat ctctaaaatg ttcatgcaat ctttgtctcc
     1201 tctagcagac gctatgtcag aatttatgaa aaagcggttt aaggatcgtg aagtatatat
     1261 cggattggac tggccgatat tagctggtcg ttcagaaatt tgggttactg ctattttact
     1321 tgttcctgtg tttattggtt atgccattat tttgccagga aaccaagtat tgccattagc
     1381 agggattatc aactattcga ttgcggtcgg cggattactt ttaacaggag gaaacttggc
     1441 tcgtatgctg atcttgggaa tcatcactat gcctatttat ttgtacgggg ccacttacct
     1501 tgcgccaata ctcagtgatt tagcagaaaa aagcggagca gtcgagggaa tcaagaaagg
     1561 acagttgatc acatggtcat ccatagaagg gccggagttc agggttttat ttgcggaggc
     1621 atttaatagg aatattctcg ctattgtagg atgcgtgatt tttctaggac tgtttgttct
     1681 actttataaa tatatgataa aagcgaaagt accgagtgaa cgttatgctg aactacaaaa
     1741 atagcattga aatggtggga aagtaatgaa aagagaagag acagataaaa taaaatggac
     1801 agtcgctctt tgtggtacac ttctgctatt tctatatgga ctctttactc agaatatcat
     1861 catcaatcta ttggtcattt ttttcgcact agtgatctat aaatatggaa atcacgtttt
     1921 attcagagag tacgatgaaa aaagaaaacg gaaaatagaa gaatcaatga aaataaaaga
     1981 agctaccaaa gaaatattga gagaaaaaag ttttataaaa agataatgga ggggtcatta
     2041 tgtcagatgg acgtatgtta tttgagagag aacgacagga catggcacgt atcgtaagag
     2101 tgattttcga aaggaaaaac acaaatgtcg caggagggaa tttttccttt aaaaccactg
     2161 atgatcaagg gaaagactac atcatcatga cgccgaccat gatgtcagaa gcctatctag
     2221 gagagatttc tcctgcacag gttctagtag tagaaccaag aacgcgtaga atcgttgacg
     2281 gagtcggtca tttaactcgt gaaatcaata tgcatgaagc gatgtatgag actaatccag
     2341 ctatcaaagc tgtcctacat gctcatgcgc ctaatgcaat gttctgggcg actactgggt
     2401 tgcctatgcc taatttgaca gaagccacag ctaaagtaaa agagattcct gtcatggact
     2461 ttgagcctaa ttgctctgaa gaacttgctg aattgacaag cgactatgta aaaaaacagc
     2521 atctcgaatt accgcatatg ttgctgctca actctcatgg cgtattgatc aacacaggtg
     2581 gagaatcagg aatcgaagct atccataaag cactgcaaat ccttgataca gttgaatgga
     2641 atgcagaaat tgcctacaag cagacgattt ttcaagcatt agggattact gacggttttt
     2701 attcaaaagg tgagaaaatc gggggattgg aagagttgaa acataaaacg gctatttata
     2761 ataaatctgt tattgcagct ggtggagact aacctatctg acacaaaaaa ctacgacttt
     2821 cacaaaatct gatccagatc gatatctgct tcaggttgta ttatgtaagt cgtagttctt
     2881 ttcttttatt tagttaagag gtggtctgtc cattccctcg cttgcttgat ttcgtccatc
     2941 gtcaactgat gacctgttac agttagctga atagtcacat ttgcttggcg tgtttcgaat
     3001 tgatcggcca attctttaaa ggaagcaggg gaaacgattg gatcgttatc accataagaa
     3061 atccagacgg ttttatcctc taatgtggaa cggctttgat gaacacctag agacatcgga
     3121 tggaaaaaca accctttatt tagctcggtc tcacgctcca ataataaatg agcagcgatg
     3181 tttgcgccat ttgaatagcc gacaagcagc cagtcactta acggtatcag ttctttttcg
     3241 ctgatttctt tgattttttc atggagttta tctgtttctt tttccaaact gtccaggtcg
     3301 aattgattca atccattacg cttgaaaaaa cgattcatcc catcttcttg gaccgtgcca
     3361 cgaaaagaaa gcaatgtact gtttggtgca agaaagtgag cgatatccag taaagaatgt
     3421 tcatcgccac ctgtgccatg aagtaagatc aaatgcttgc cacttgttcc tttttcaaaa
     3481 atgtaggtca ttttgttccc tcttttctgt ttctatagat gcaaatgaag tagcatgaag
     3541 agattattca cgttttttat ttgcatcact tgtatcgaaa ggacggacat aagcttcaat
     3601 ggcttcacga cgttcttcta agaatggagg aagagatagt ttttctcctg ctgattctgc
     3661 tggttcatct tcaaggaatc caggaccatc agttgctaat tcaaacagta cgtgatgagc
     3721 ggctaggaag tactcagatt ggaaatagaa acgatcgacg aaaccagaat ttggcaattc
     3781 aatcttattg attacttgaa tccagtattc caatgcttct ttgtctgcta cacgcaatgc
     3841 taagtgatgg atatttccaa atccttcgat tgcttttggc aagtctgtcc gatgttcaat
     3901 aatgatgctt gcaccatttc ccccttcacc gatttcaaat aagtagaaat ctcctgaatg
     3961 gtctgtttct ttgaatccta agattttttc aagaatcaag cggatatgct ctaattgact
     4021 gacacggaca aagacaggtc caagtcctgt gatcgcaaac tctgtcggta cattgctgtt
     4081 tttccaagga atgccagctg ctacaccttg attgttttcg tcagagatca attgataata
     4141 ctgattatcg aaatcttcaa attcgatata ttttttgccg aaacgttcat tgattgctga
     4201 atgagtaacg tcatattttt caaaacgttc caaccaaaag tctaatgctg cgtcacttgg
     4261 cacacggaaa gaagcacgag agatcgtatc tgttcctttt tttccttttg gctgatttgg
     4321 aaaatcaaag aaagtcatat ctgttcctgg cgcaccagta tcgtctgtaa agtaaagatg
     4381 gtaagtttcg atgtcatctt ggttaactgt ttttttgatt aagcgcattc ctaaaatatc
     4441 tgtaaaaaag cggtagattt ttgtagcgct agatgtcatt gctgtgacgt ggtgaattcc
     4501 tctgatttgt gtatccatga taaatttcct cctgttaact tacaaaaagt aagtagttga
     4561 tttagacata gtatagaggg tgcatctcta ttttgcaatt aatttgtctt ctaaagtatc
     4621 aggaaggaat caagaatgga aaagaggagg gacggatcaa taaaataaaa agacttacga
     4681 ctagctgtat cgatttcaaa aaaactagct ttaaaaagct aactttagaa tcattacggg
     4741 tggtcataag tctttttatg ctgagttatt ttttcatttt tgagctaatg cttaggatag
     4801 aatagaatgt tgatttcacg atctcttctt gttacttgaa actgcttacc actgtcacga
     4861 tctcttggta aacggctttt tcacaacctc tttggttaag ttgaacgcac atccagcaca
     4921 gaatagttcc gaacatcaaa tcggtttcgg ctggaagaat attcaatcgg ctgtccatct
     4981 ttgagataga cgacttgctg aacttccagt acaggatcgt tttctgcaca gttcaaatat
     5041 tgctgatcat attcatcact tttatctgca gaaatagcac gataagcccc tgcaaaatgg
     5101 acattcaatt cttgatgaag atgatcatag atagaggcta acaaatgttc tttttttaaa
     5161 cccggcacaa gatggactgg cataaaggta tgctctaaaa catatggctc gccatctaag
     5221 atccttaacc ggtgaatatt gtagacaggt tgctcggcat cgatcatcaa tcgttcttgg
     5281 atatattgat tagggaattc aacatcaaaa tgaatgattt gactcttcaa agaacgatgt
     5341 ctgcgtttca tttggagact caaaccttca tactcgttag cgggcgatgt gtctttttgc
     5401 ataaatggat gattcaagat tttcgttcct gatcctcgct gcgaatagac aagtccttcc
     5461 attgctaaga tattgatggc ttttttgatt gtcatccggc tcgcaccaaa ttcttttacc
     5521 aagtcgactt gattaggcaa aaaactatcg agaggatact cttttgaacg gatacgttct
     5581 cttaaaatat ttgcgatttc ttcgtatttt ggcacgttat tcacctcttc tagagtataa
     5641 cgaaagatta tgcttccgac aactcgaagt agcatctgga acattgttta ttcgaaaaaa
     5701 gaggtcatga caagtttttg tcacaacccc ttaatgatct attaagcaat atctaaatct
     5761 ggttgtttat ctagtacttt caggaatggg taccagataa aggcaacgat gacaaagtcg
     5821 atgacttgca gcataccacc aagccatgaa tttgttgcta agacaccgct tgcaatgatt
     5881 ggcacagtcc atggaacaga gacgccagtt ggtgcaggga caagtccagc agccattacc
     5941 aaataattga acgtcgttac gattagaggt gccacaaccc aaggaataag gattgttgca
     6001 ttcaatacga tcggtagacc gaagatcgct ggttcattta cattgaaaat accaggtgct
     6061 aaagctaatc gtccaacatc acgatactgt ttctttttaa gaacaaaggc catcaataaa
     6121 acgacagcta aagtcattcc agagccacca ataccaacag tgaaggtttc catgaatggt
     6181 tttgtgatga tgtgtggtaa ttcttttcca tgttgataag cttctaagtt atcaagcatc
     6241 agtgtattcc aaatcgggtc cattacagag ttgacgatga tttgtccgtg aagtccgaag
     6301 aaccataaga attggacaaa gaacaaagca atcaatgttg caggtaaact acttcccaaa
     6361 ccagttaatg gtttttggat cacttcataa acgacgtcat gtaagttagc attgaaaata
     6421 ccagtcatca cagcattgat tactaagaaa atagttagtg tcactacagc agggatcaaa
     6481 gcggcaaatg attttgttac tgcaggcgga actccatcag gcattttgat ctgccagccg
     6541 cgtttcgtga ttctgcagta gatttctcca gccaagaaag cagcgattat tccaatgaac
     6601 attccttttg cgccaagacg atcaagtgaa agcacaccag tcacatcttc accgccagcg
     6661 gttttcattg caaaaggcgt aagaatcaag aagctggcaa aagacacggc accaccgaaa
     6721 ataccttcaa cgtcataaga ttttgataaa taatagccga taccaaaagt aacaaaaacc
     6781 gacatgatgc tcattgttgc attttgccca ttaccgaata aattcgataa agttcccttt
     6841 gttgcgtcac tgaaaaaagg caagttattg ataacgacaa cgatcgaacc gaacatcgtt
     6901 aaagggaagg aaagcatgaa agcatcccgc agcactgtaa ggtaacgatt ttgccctaat
     6961 aaattagcta agggcatgat tttctcagaa agcttgtcca taaaaccgtt catttttatt
     7021 cacctcaaat ttatttgcaa tcgattacat acaaagtata acgccaaaaa ttttaaatgt
     7081 ctagtcattt tcataaaaag tattgattta ttttttaggg ttcgttatga ttacggtatc
     7141 aagaaaaaag agaggaagta aaaaaatgaa aacctacaca ttcccagaaa atttttggtg
     7201 gggttctgct gctagcggac cgcaaacaga aggaagagta agtgatgatg gtaaaggaga
     7261 aaatatttgg gatcattggt atgaattaga gcctgaaaaa ttcttcgatc aagtaggacc
     7321 tgaaaaaact tcgcaagttt acacaaaata caaagaagat gttcagttaa tgaaagaaac
     7381 tggccataac acatttcgta catctatcca atggagtcat ttgattccag aagggacagg
     7441 tgaaatcaat caaaaagctg tttcttttta tcgagattat tttactgaat tgctggataa
     7501 tggtattgaa ccttttgtga acctttacca tttcgatatg ccactaccac tgcaagaaaa
     7561 aggcggatgg ttatcaagag aaacggtcga cgcttatgtt tcttatgcag cagcgtgctt
     7621 tgaactgttt ggagatctgg tcaaaaaatg gtttactcat aatgaaccaa tcgtacctgt
     7681 agaaggaggc tacttgtatc aattccacta tccaaatcat atcaatatga aagaagcggt
     7741 ccaagtaggc tatcatgaga atctagcaag cgcaaaggta atcaaagcct accatgaagg
     7801 cggacatgat ggtgagatcg gaatcatctt gaatctgaca ccaagctatc cgagagatga
     7861 aacgaaccca gaagatgtaa aagcggcgaa gatcgctgac gcattcttca accgatcatt
     7921 ccttgaccct gcagtgaaag gagagtttcc acaagagttg atcgaaattg tcaaagaatt
     7981 ggctataatg ccagagatcc atgaaggaga cctagaactc atccgtgaaa acacgattga
     8041 cctgctagga atcaattact atcagcctcg tcgaatcaaa gcaaaagaaa ctccaatcaa
     8101 tcacgaacat agccccatgc cagatgatta ttttgataat tacgacatgc ccaataaaaa
     8161 aatgaatcca tatcgtggat gggaaattta cgaaaaagga atctatgata ttttaacgaa
     8221 tacaagagaa aactatggta atatcaaatg ctatatttct gaaaatggga tgggggtcga
     8281 aggagaagaa cgatttgtta acagcgaagg aattattgaa gatgattacc ggatcgagtt
     8341 tgttacggat catttgaaat acgtccatca agcaatccaa gaaggaacca attgtgtggg
     8401 ttaccacatg tggacatgta tggacaactg gtcttggaca aatgcttata agaatcgcta
     8461 tggctttatc gctgttgatt tggcacaaga cggtaaacgg acgatcaaaa aatcaggtcg
     8521 ctggtttaaa acggtctctg aaaaaaacgg atttgatgcc tgatattttt tgataaaacg
     8581 ttcacaaaat gtttgttcta acactgtaat cgtgctacac taacagtgaa ggaggcgttt
     8641 acaatggtag atacttatcg taatatttta gtagcaattg atggttctga aaaggcagaa
     8701 aaagcatttc ttgaggcaat cacgattgcc aaacgaaatc aggcaacgtt gcacatcctg
     8761 tatgtcaatg aagtaacagg caattacttt ggtgattttg catttgttac aacaagcctt
     8821 caggaagaat tggatgaggt tgcggaaaac cagatgaaag aacatcgaaa cttggcaatt
     8881 gaaaaaggcc tgacagatat cgagacatat gttctttacg gttatccaaa gacactgatt
     8941 gctaatttcc atgaatcgaa agaaccaatc gatctgattg tcatgggggc gacaggtctg
     9001 aatgcggtag aacgtgcact agtaggttcc actacttcct atgtagtcaa ccacgcatca
     9061 tgtaacgtca tggttgtaaa ataaataaat taagggaaca gaaagcaaaa aagcataacg
     9121 cttcttttgc tttctgttcc ttttattttt ttgtaaaaaa ttactttacc tgatgaagta
     9181 atcatgctat tctaattaca acgacagatg gagtaatatg gaggaaagaa aatgatttca
     9241 agtgatggaa tacgcggata caatgatgcg attattttat cgatccttaa caaaaacgat
     9301 tcttatggat atgaaatttc taaaacgatt cgtgagagga caaatgattc ctatgtgatc
     9361 aaagagacaa cactttactc cgtttttgcc cgtttagaaa agaatcaact gattgtttcg
     9421 tatcctggag aagtgactca tggaaaaaag cggacatatt ataaaatcac tgaaataggg
     9481 cgtaatcttt tagaagaaaa aaagcaagag tggctgacga cgaaagacgt agtcgatcaa
     9541 tttttggagg gaaattaaat ggatacaatc cgtaattatt tagacagtct ttttatcgga
     9601 gtacctcaaa gtaccgagat agataagctg aaaactgatt tgttggcaaa tatggaagac
     9661 cattatcatg aattgatggg agaaggaaaa aatgaacagg aggccatcgg tacagtaatt
     9721 tcgacatttg gttcaatcga tgaattatta gaagaactag atgtcgaaaa aaaacatcaa
     9781 gctgacgaga cggaaacaaa cacagcttct atttatttaa gcgaagcaga aaactactgg
     9841 aaagaataca gagcggcaag tctccaagtg gcatcaggtg ttctattcat tagcttatct
     9901 tttgcaagtt ttcttttctt ttgttcagca ggatatgtgt tcatgggtat ttcttgtctg
     9961 attttcggta tagcattagc tgtcggtttt tttattgctt ctggtatgaa aatcacacgt
    10021 ttaaatcact ttttgcacca tcggaaaata cctgaaaaag tattagcaga agcaaaagaa
    10081 aaagaagaag agtatcagcg aagttttggc ttctcactga ttgcaggaat tggattatgt
    10141 attttttcac ttttcccact tttggcttct ttaatgtggt atatggatgg tagtatcggt
    10201 gcctctatat tttttgttac ggtaggaacg ggtgtcttct tgatcattta tggcagtcta
    10261 gtccgtcatt cttatcgtca attcactcaa agcgcttatt actggtgaat gtattcagat
    10321 ttgtaaaaat attctattta tccggcgtag aaaaaaagac tgtga
//
LOCUS       DAFLVO010000087         9886 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.089, whole genome shotgun sequence.
ACCESSION   DAFLVO010000087 DAFLVO010000000
VERSION     DAFLVO010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9886
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.089"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(109..2229)
                     /locus_tag="L1U99_002461"
     CDS             complement(109..2229)
                     /locus_tag="L1U99_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBN1212982.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2459..3637
                     /locus_tag="L1U99_002462"
     CDS             2459..3637
                     /locus_tag="L1U99_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HBN1212983.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3653..4411
                     /gene="aroD"
                     /locus_tag="L1U99_002463"
     CDS             3653..4411
                     /gene="aroD"
                     /locus_tag="L1U99_002463"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBN1212984.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4434..4919
                     /gene="ybaK"
                     /locus_tag="L1U99_002464"
     CDS             4434..4919
                     /gene="ybaK"
                     /locus_tag="L1U99_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBN1212985.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4990..6243)
                     /locus_tag="L1U99_002465"
     CDS             complement(4990..6243)
                     /locus_tag="L1U99_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBN1212986.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6360..7709
                     /gene="gdhA"
                     /locus_tag="L1U99_002466"
     CDS             6360..7709
                     /gene="gdhA"
                     /locus_tag="L1U99_002466"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HBN1212987.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFISGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7821..9167
                     /locus_tag="L1U99_002467"
     CDS             7821..9167
                     /locus_tag="L1U99_002467"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBN1212988.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9475..9861)
                     /locus_tag="L1U99_002468"
     CDS             complement(9475..9861)
                     /locus_tag="L1U99_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBN1212989.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         3149 a         1800 c         2024 g         2913 t
ORIGIN      
        1 ctgagccaga atgaggttca ttctgaccca gatttgattt tgtacaaccc atcagtcctt
       61 attgacaaag agcctaattt tgtcgctgct ccttttaaat ttattttatc attcggaaga
      121 acttgtggtc gttccgtgaa gttcttggta cgtttgcgtt ttataaagat caacagttga
      181 ttgtccgttg tgttcactaa agacactagt tgacttgtca ccaagagatt tttcagcttc
      241 ttttaatttc tctaagccat tcttgtagtc ataatcactg gtatcaattg ggtctaatcc
      301 actattcgta tagaaccgaa gaagatcacc attattgatt tggtcagaaa cagctaactg
      361 tttatcaact ttttctttca gtgaatcaat ttcattctgt acttcctcag taggttcagt
      421 aatagcttca ccagtttcgt tactatagat cgtaccaccg tagtaagtat attttggtgt
      481 aacaaaatca ccatcacgga aagaaacaag ctgttcatga tctttcgaga atagatcttg
      541 tcctaactga atataatttt ttgtatctac acctagtaag tgaagtaatg taggcaaggc
      601 atcaacttgt ccgccgtaag tgtgattgat tccgccctgt gtttgtccag ggatatggat
      661 catataaggg acacgctgca tttgtgcatt gtcgtagttt gtccaagtag aacttgtttt
      721 tccaactaat tcagctagat ttttatttct tgaattcgag acaccgtaat ggtcaccgta
      781 aaggacgatg actgaattat catacaagcc gctttctttc aaataattga agaattcttg
      841 tacggcggta tctaaataat tggctgtcgc aaagtaaccg ttgatcgttt catcatttgt
      901 attggctaac gggaatcctg cttcgtcatt ggtgaatttt gaataaggat aatggttaga
      961 tacagcaatg aattttgaat aaaatggttg ttgcagacgt tccaagtatt gtacggattg
     1021 ttggaaaaat ggtttatcat gcaacccgta ttggaacgaa ttgtcatcat taacatcata
     1081 ataagaagaa tcaaagaaat aatcatatcc taaattcttg tatgtctcgt ttcgattcca
     1141 gaatgtacca gcgttcccat ggaataccgc actagtgtaa ccttgtgttt gacttaaaat
     1201 atcaggtgca gcttggaaag tattttttcc gcctaattgt gtgaacaagg agccttgatt
     1261 caagccaaac aatgaatttt ccatcagcgt ttccgcatcg cttgtttttc ctgcttttac
     1321 ttgatggaaa aagttgtcaa aactgaacgt gctgttgctg tggtaaagac tattgatgaa
     1381 aggtgtaact tcatgctgga gaccattctc atctgtcaat ttataatcga tcaggaattg
     1441 ctggaagctt tctaaatgga tataaatcac attttttcct ctagcgagcc cgaacaaatc
     1501 gtcatttggt gctgcataat gttcttttac ataattttct acttctttca tatcattggg
     1561 acttgcttct gcccgcactt ggtttgtctg gtaagtttga acaccgtcat aaaccatgaa
     1621 agcattcaag ccaagatatt tgaccaaata atcacgagag aatgttcgag tcagcaattc
     1681 tggacgatca gcttccgcca taaaaagatt tcctgagaaa atcataactg ctaatgtaga
     1741 gatcgcaaaa gccattcttg ctcggatcgg gcgagggtcc aacttgattt tttttgcaat
     1801 cagcagaaca gtcaagataa taaaatcgat ccaatagatc acatcatatg ggcgaaacag
     1861 tcgaatggca ctttctccca gaccactcgc tactttccca gcacctaaaa tcgtgttgat
     1921 cgtaatgaag tccgtgaatt ctcgataata agtgacattc gaaaaaacaa gcaatgtcaa
     1981 aagaaaataa atgaccatca tcgtgatata agcaactcta gggcgtctga tataaagagc
     2041 aattccaagt aataacaatg tagttgcaat agggttgata aacaagataa agtattgaat
     2101 gccactttcg attccgagat ggaaatcaac taaataggca aaaatcgttt tcaaccaaag
     2161 taaaacgact agtaaagaaa aaaatccgag cctcttattc aaaaaggcag gtgtttttat
     2221 acatttcaag ataatcttcc tttctgcact tcttaatcac agaagtgtcc tgaaaccatg
     2281 ttacacagct cacttattct catttatttt actagtatga caatatagtg tcaattgaaa
     2341 ccagaagttt atgctgtttc attaaggttt tctttaagct tcatgaaaaa atgagcagta
     2401 agacaagtcc tatgtttttt gttatacttg ggaagagaaa gctaaagcag gtgaaggaat
     2461 gaaagtaaaa gtaaaaaaaa gagcaagcaa tcgattgaaa aaaggatatc cactgatcca
     2521 aaaagaagac cttgctcatc cccaaaaaga aaccacgcaa tgggtggaat tagttgattc
     2581 gcaaaaccaa tttatcgcaa aaggatatct aggaaagcag aataagggaa tcggttgggt
     2641 attgagccag cagaacatcc catttgatca atcttttttt gaagaatttt ttgtgaagtc
     2701 aaaagaaaaa agaactttct ttttttcaga tgattctact accgcttttc gtatattcaa
     2761 tggagaagga gacgggatcg gcggtctgat tgttgattat tatgcaggtt atgctgtttt
     2821 ttcttggtat aacgaaacgt tatatgcaca tcgtgaatta ttgattcaag cttttcgtga
     2881 aatctacccg gaaatcatag gaggctatga gaaaattcga tttgaatcag taaatctgcc
     2941 tgagagccag ttcatttacg gaaaagaggc accggaaccc ttgatcgtaa aagaaaacgg
     3001 agtaaaattt gccgtttatt taaatgaagg attaatgact gggatctttt tagaccaaaa
     3061 agaagtacgg ggatcattag cagaaggttt cgcttctggg aaaacagttt tgaacatgtt
     3121 tagttatacc ggcgcctttt ctgttgctgc cgcaatggga ggggcaatcg aaacaacaag
     3181 tgtcgatcta gcaaaacgca gtttaaaaaa aacacaggaa cagtttgaag tgaatggttt
     3241 ggatgtcgat cagcaaaaaa tcattgttat ggacgtattc gagtatttca aatacgccaa
     3301 aagaaaacaa tttttatatg acatgattgt attggatcca ccaagttttg ccagaaataa
     3361 gaaaaaagtc tttcgcgtag caaaagatta tggggaactg gtcaaggata gtctggatat
     3421 tttagcagaa gacgggatac ttattgcgtc tacaaatgct gcgaatgtct cgatagaaca
     3481 attccaaaca atgattgaag aggaattcca tgccaaaaat gtttcttttg aacaacttgc
     3541 tttatatcgt ctgccaaaag atttccagac gacggatacc tttttagaag gcaattatct
     3601 gaaagtgttt gtttatcaaa ttaaaaataa ccattagaag gagcgatgca gaatggttcg
     3661 ggtaaaggga ttgaatatag gaagcggtag accaaagatt tgtgcgcctc ttatcggggc
     3721 cgtccgagag gaagtattac gtgaagcagt tcttgcacgt gaagcagggg ccgatttagt
     3781 cgaatggcga gtcgatcatt atcgtgaagt tttttctttt gatgaagtag cagaaacatt
     3841 ggttcttatc catgagatgc ttgatggact gccgttatta tttacgtttc gtaccttagc
     3901 tgaaggcgga gaacaagaca tatcgatccg tcagtatcgc gacctttatg aacatgtgat
     3961 acacacagga ttagtagata tggtcgatat cgagttgttc aaagtagaaa gtctaggaaa
     4021 aagactgata gaggaaatca agtctttaaa cattccttta attatcagta gtcatgattt
     4081 taaagaaaca ccagcagacc ctgtcttgct ttaccgattg aatgttatgg aacattttgg
     4141 agccgatatc ggaaaactgg cagtaactcc caataatgaa cgagatgttt tgcggttgat
     4201 ggagttgact agacgggcaa atgcttttgt ctccatgcct attattacga tgtccatggg
     4261 aaatcttggt aaaatttctc gtctggttgg cggaacgacg ggttccgtta tgacatttgg
     4321 ttccttaagc agcgattcta cttctgctcc aggacaatta ccggtcaaag cattgaagca
     4381 aattattcaa ttattaaatg aaccgttgta gaacaagttt gaggtgatat tttttggcaa
     4441 agaaaaaaat agtaaaaacg aatgcaatcc gtatggtcga acaaaaaaag attccctata
     4501 cagagcacga atatgagtgg gacgaaagcc acctaagtgc gtcatcggtc gctgaacagc
     4561 ttccagaaag ccaatctcgt atatttaaaa cactggttgc tgtgggcaat gtgacggggc
     4621 ctcttgttgc tgtgataccg ggagaagccg aattgaatct aaaaaaatta gcaaaagttt
     4681 cagggaataa aaaagtagaa atgctccatt taaaagattt ggaagcaacg accggataca
     4741 tacgtggtgg ctgctcgcct ataggtatga aaaaactatt tcctacttat ttagatcaaa
     4801 ttgcagaaag ctatgaacaa atcattgtct cggctggcag aagagggcta cagatggagt
     4861 tagcacctca agatatctgt gcattaacga gcggacaatt tgcagatata aaacaataaa
     4921 tcatacgtat aaaagaaaga aggaggccgg gatgttgttt gtccagtctc cttctttctt
     4981 ttttatacat tatgctcttt gcccggcatt cattcctgct acatgccctg tagcgaaagc
     5041 cgctgtgata ttaaagccgc cagtataacc attgacatcc agtaattctc ccgcaaaata
     5101 cagaccatca atgattttac tctccaatgt tttaggataa atttccttta gagaaacccc
     5161 tccgccagtt acaaatgatt tctcaatagg aaaagttttg ttgattgata gcttaaactc
     5221 tttgcatagt tgaacaaaat cttgaatttg tttttgagag gcttgttgtc ctgtcagatg
     5281 atccatttca agccgctcaa gaaagaaaac taacaatcgc tcaggcaata taccatgcca
     5341 agcattgacc aagttctttt tggttgcttt acttttttct gtcaatatat gaataagctc
     5401 ttgtttggtt tgtgtaggga aacaatccag agaaagtgtc actggttctc ccgttttctc
     5461 taattcttta ttgacaaaac ttgaacaacg cagtgcagcc ggaccagaaa taccgaaatg
     5521 ggtgaaaagt aaatccatcg tatgttcagt caatacacga ccttttttat ttaaaacgcg
     5581 taaagtgatg tcttgtaaag aaagcccttg aagtgttttc tcctgaatat acggttcatc
     5641 cgatatcaag ggggactctg tcgcataaag aggcgtcacc gtgtgaccca ctcgcttcac
     5701 gatcttgtac ccatctccag tagaaccagt agatggataa gtccgtccac cagttgttaa
     5761 gataatggca ggagcatgga actcttcgaa ttccgtgcgt ataccgtaaa ttttatgttc
     5821 tttgtggatc aatttctcta ctcgagtaga gaatagaagc gtcacatcta gttctttcag
     5881 acgattgagc aatgcttcga taatcgtttt tgatttattt gttacaggaa acatccgtcc
     5941 atgatcctct tcttttaaat gtacgccttg tgattcaaag aagttcatga tatcgaaatt
     6001 attccattgc gcaaacgtac tatataaaaa ctttccattt ccaggaatat gtgcaatcaa
     6061 atcatcaaca ggacgattgt tcgtaacatt gcaccgacca ccacctgtca tcagtagttt
     6121 ttttcctgct tttttgtttt tttcgatcaa gagtacgcgt gcgccttgtt cagctgcact
     6181 gatcgctgcc atcatcccgc ttgttccagc gccgactacg atcacatcat acagtttttc
     6241 cattccctca cctcaaggaa agtgtagcat atctgaagaa agaaaacaga aaaaaatgtt
     6301 ttgagccaaa agagaaaatg agctaaaatg agggaagata agcaaaggag cgtggaacga
     6361 tgacaaacgc aacagaatat gttcaagcaa ttcaagaaaa gctacatcaa aaggatcaag
     6421 ggcaagaaga atttttacaa gcaatcgatg aattcatgcc cacggttatg tcttttttgg
     6481 acactcatcc cgaatatatc gaaaagaata tcttagaact tttaacggaa ccagaaagag
     6541 ttattcaatt tcgagtgcct tggcaagatg atgaaggaaa ctggcgagta aatagagggt
     6601 accgtatcca atacaactca gctatcggcc cttataaagg tggattgcgc ttccatccta
     6661 gtgtcaatct aagtatcttg aaatttttgg cttttgaaca gattttcaag aatagtttaa
     6721 ccggtctgcc aatcggtgga ggaaaaggcg gaagtgactt cgatcctaaa ggaaaatctg
     6781 ataatgagat catgcgtttt tgtcaaagtt tcatgctgga attgtcaaaa catatcggcc
     6841 catcgattga tgttcctgcg ggagatatcg gtgtaggagc tagagaaatc ggctatttgt
     6901 tcggcgaata taaacgattg aaaaaatatg atactggtgt gttgacaggt aaacctttgg
     6961 atttttgggg aagtaagata cgtacggaag ctactggtta tggattagtg tattatgtca
     7021 aacatctatt gaacgaagaa aaagattcat ttaatcaaaa aacagttttt atttccggaa
     7081 gcgggaatgt agccatttat gcaatcgaaa aagtgcaaga gctaggcggg aaagttgtta
     7141 catgttcaga ttctagcggg tacatctatg atccagaagg aatagatgtg aaactattga
     7201 aagaagtcaa agaaatcaat agacaacgtt tgacggaata cgcaaaccaa cgtccttctg
     7261 ctatttatca tgctggagaa tctgtttgga cattgaaaga aaaagcggat atcgctttgc
     7321 catgtgctac tcaaaatgaa atagacgaaa gcttggccga aatcttagta gaaaatggga
     7381 tcaaaatcgt agcagaaggc gctaatatgc catgtacagt aaaagctgtt tctgttcttc
     7441 atgaagcagg cgtgtggtat tgtccaggaa aagctgctaa tgctggagga gtagcagtat
     7501 ctgctttaga aatgagtcag aacgtccagc gattgacttg ggaaagagag caagtggatg
     7561 agcagctgga tcaaatcatg gaaacgattt accatacgtg tcgccaaaca gcagccgagt
     7621 acggcgacga aaaaaatctg cttcttggag caaatgttgc tggatttgaa aaagttgcca
     7681 aagcaatggc agcagaaggt ttagtttgaa aaatgaaact ttcttggaaa tattgtcagc
     7741 attttgttta tttgcttgaa aaataataaa aaaaaacgta aagtattacc tgtagagtaa
     7801 acctataagg aggagaacaa atggcacaca ttcattttga ctattcaaaa gtagcaccgt
     7861 ttgtcaacga acaagagtta gggtacatgc aaagccaagt aacagcagcc cacaacgaat
     7921 tacgggaagg tactggcgca ggaagcgact tccgcggctg gatcgattta ccaacgaact
     7981 atgacaaaga agaatttgca cgtatcaaag aagcagctaa aaaaatccaa tctgattctg
     8041 aagtattagt tgttatcggt atcggtggtt cttatttagg cgctcgtgca gcgatcgact
     8101 tcttgaatca cacattcttc aatttattag atagcaacac aagaaaagca ccacaaatct
     8161 tctttgccgg aaattcaatc agctcaacat atattgctga cttgatcgaa gtaatcggtg
     8221 atcgcgactt ttcagtaaac gttatttcaa aatctggaac aactactgaa ccagcgattg
     8281 cgttccgtgt attcaaagag cttcttgtta agaaatatgg acaagaagaa gcaaacaaac
     8341 gtatctacgc tacaacagat aaagcaaaag gtgcagttaa agtagaagca gatgcagaag
     8401 gttgggaaac tttcgtgatt cctgatgaca tcggcggacg tttctctgta ttaactgctg
     8461 ttggtttgtt accaatcgct gttagtggtg cagatatcga tgcattgatg caaggtgccg
     8521 ctgatgcaag caaagcatac tcaagcgaca aactagaaga aaacgaagct taccaatacg
     8581 cagcaatgcg caacattctt taccgtaaag gcaaagtaac tgagttgttg atcaactatg
     8641 aaccaggaat gcaatacttc tcagaatggt ggaaacaatt gtatggtgaa tctgaaggaa
     8701 aagaccaaaa aggcatctat ccttcaagcg caaacttctc aactgatttg cactctttag
     8761 gacaattcat ccaagaagga cgtcgcaata tttttgaaac agttgtgaag gttgaaaaac
     8821 ctcgtaaatc aatcacaatt cctgaacaag cagaagattt agacggtcta ggctacttgc
     8881 aaggaaaaga agtggacttc gtaaatacaa aagcatttga aggaacattg cttgctcata
     8941 cagacggtga cgtgcctaac ttgctagtca aaattccaga aatggatgct tatacattgg
     9001 gttatacaat gtacttcttt gaaattgctg taggtatttc aggttacttg aatggaatca
     9061 acccattcga ccaaccaggt gtagaagctt acaagaaaaa catgttcgca cttctaggca
     9121 aaccaggctt tgaagatctt gctaaagaat tgaacgaacg cctgtaagat aagggttttt
     9181 cgctagattt aaataatcag tgatagaaac atgttcgctt taaaatgaaa actggtaccc
     9241 atttaggtac tcaaacatac tgcatcgttt attcagaata aggggctgtg acaagacgtt
     9301 tgtcacagtc ccttgtttgt atagaaatcg attgattgcc ttgctcttta gtttgtttta
     9361 ggactttaag aacagtgagg ctgacttcga aggttaattc tgtttttttg ttttctagaa
     9421 tcagtaagca aaaaagcact cacttcgagt gcttttttgc gatatattct tagcttaaga
     9481 taggcctaat ttttctttta cagatgaggg taccttatcg ctggtaatta cttttttctc
     9541 tatgatccgc ttttcgcttg ctttcaactg caagatcgtt ccttcggggt aagcagaacc
     9601 attggcagag tcaccagaag taatgacatc gaaatctaac tgtctttttt caccgttttc
     9661 agcataagca tctacgttgt atttaaaacc tcttccaatt acttccccat tatctgcttt
     9721 gatatcagtt tctgcaggca ttggagcttt gactaccgca taataatctt tacctacata
     9781 agtagactga tagtagtccc aacctttcca tcctataaaa gcaatcaata tgataacgat
     9841 caaccctaaa atttttttca tgaaagatct ccttttttat ttttat
//
LOCUS       DAFLVO010000088         9858 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.090, whole genome shotgun sequence.
ACCESSION   DAFLVO010000088 DAFLVO010000000
VERSION     DAFLVO010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9858
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.090"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            278..787
                     /locus_tag="L1U99_002469"
     CDS             278..787
                     /locus_tag="L1U99_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1212990.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="L1U99_002470"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="L1U99_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBN1212991.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..3302
                     /locus_tag="L1U99_002471"
     CDS             2322..3302
                     /locus_tag="L1U99_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1212992.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3424..4842
                     /locus_tag="L1U99_002472"
     CDS             3424..4842
                     /locus_tag="L1U99_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HBN1212993.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4913..6382
                     /locus_tag="L1U99_002473"
     CDS             4913..6382
                     /locus_tag="L1U99_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1212994.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6392..6859
                     /locus_tag="L1U99_002474"
     CDS             6392..6859
                     /locus_tag="L1U99_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1212995.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6895..7767
                     /locus_tag="L1U99_002475"
     CDS             6895..7767
                     /locus_tag="L1U99_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1212996.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFIKSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7848..>9858
                     /locus_tag="L1U99_002476"
     CDS             7848..>9858
                     /locus_tag="L1U99_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1212997.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAK"
BASE COUNT         3414 a         1430 c         1972 g         3042 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga tccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa aatacagcat
     3301 aagttaaatc ggcgaaaaat tccttcgtcg atttaaaaat atttttatga aacgggttga
     3361 catatgaaac gggttgacat atattagttg tgaagataaa aaccttttca ctggaggaag
     3421 aaaatggaga aattattaat taaaagcaat aatcatcaac tttactacca acctaaggat
     3481 gtttgggtcg gagatgttat gccttacggg aaagaaggaa aattctttat ttatcatcaa
     3541 cgtgatacta gaaatccagt tccttttgga gaaccgtttg gctgggcttt agcaactacg
     3601 aaagattttg ttcattttga agactttggg gaatctcttt taagagggga tgacaatgag
     3661 agagaccagt ttatctacgc tggttctgta tttgaggcaa atggaaaggt tcacgcattt
     3721 tatacagggt ataatcgtga attcttagcg cagggaaaga catctcaagt gttgcttcat
     3781 gctgagagtg atgattttgt tcattgggaa aaatcagaaa cagcattgga gttagaacca
     3841 caagaagggt atgatattcg aaactggaga gatccatttg tcgtttggga tgatgaaaaa
     3901 gaagaatatt tgctaatttt aggggcgcga aagggtcagg ataaacatct acaaaccgga
     3961 cgtttagtgg aatttacatc aaaagattta actaattggg aattcaaagg tgatttttgg
     4021 gctccgggat tgtataccat gtttgaaatg ccagaacttt tcaagattgg tgactggtgg
     4081 tatcttgtct attcagaata ctcagatgga aataaaatac tctatcgaat gagtcaaagt
     4141 ttggaaggtc cttggattaa gcctaaagat gaagcttttg atggacgggc ttattatgca
     4201 ggtagaacag cttatgatgg aaaacgtcga gtcctatttg gatgggtacc aacaaaagat
     4261 caagaaaatg ataaaaacaa ttatttatgg ggaggtactt tggttcctca tgaagtctat
     4321 caaaaagagg atttttcact tggggtaaaa cccatagacg aagtgtggaa tgcattcata
     4381 aatttacatg atattgccga tgtagagata gaaacagcag acacaagaga agaagtaacg
     4441 cttgtcaaaa atagtggaac tttgtttaat ttagaaacaa caatttcatt tgatgagaat
     4501 cttagtgact tttcactgag attatataaa aaccttgaga cagatgaatc ttacgaatat
     4561 cgcttcaatt tagatgaggg gcgtcttaca tttgataaaa acccttgtta cccttggttt
     4621 caatatatgg ataaaggact tattagacct atatctttaa agcctaacca atcttataaa
     4681 ctaaaagtga ttgttgatga caatataatg acactttata ttgatggaat cgctcttaac
     4741 gctcgtgtac atggttgttt tggtcaagca attactatta cagcaacaaa tggatcaatg
     4801 actgcaataa ataccaagtt ttcaaatgaa ataaagaaat aataaacgtc aatcatgtgg
     4861 caggtctgaa aatcaaacat gacctgtcac atttaaaagg gaggataaat gaatggacta
     4921 caaaaaaatt gccgaagatg tattggaaaa cgttggagga aaagagaata tctcaagcgc
     4981 tacacactgc attactcgtt tacgtttaat tcttaaagac aaaagcaaag cgaatatgga
     5041 aatgcttgag gaaatagaag gtgcaaaagg tgttcttttc aatagtggac agttacaagt
     5101 aattttcgga acaggtataa ttgaaaaggt ttacaaagag ttcgttgaat tgacaggagc
     5161 taaggaagta tccgtttctg aaatgaaaga cgaaggagtc aataattcag gaaatagact
     5221 tcaacgagct tttaaagttt tctcggatat ctttattccg atcattccag cttttattgg
     5281 ggcagcaatg gttttaggaa ttcgttcgtt gattaccact cctggaatgt ttggaatgga
     5341 tggctcattc gctgatcaca atgtattcct aaatgattta tccaaatttc tgggtattat
     5401 tgcaaccaca tttgattatt taccagtttt agttatgtat tctgcaacaa aacgttttgg
     5461 cggaaaccct attttaggat tacttgtagg atttgttatg attcatccag gactagccaa
     5521 tcggaatgat ttcgtcatgg gaactataaa gcctgattat tggcatttat ttggattaag
     5581 cattccagca gttgcgtttc aagggggtgt ttttccagca attttgactt cttggttttt
     5641 agcaaaagtt gagaaaatta caaataaata ttctcctcaa gtacttgctt acattttagt
     5701 cccaactgtg acaattgttc ttgccaactt tgcactattt ttagtgtttg gtccattggg
     5761 gaattttatc ggtaatgttt taggtggaat cattgatttc ctatatatga agatgggtgc
     5821 ctttggtgct tttgtttttg caggcgcgtt acaaccatta gttgtaacag gaacacaaca
     5881 tgctattcaa ggtattgagg caaacttagt cgcaacaact ggattcaatt atatccaacc
     5941 tatttggtca gtttcaatta ttgcccaagg tggcggttgt attggtatgt atttactctt
     6001 taagaaaaaa tctaaagata gagatattgc gatttcaagc tttattccaa cactggtagg
     6061 tattactgaa ccggctatct ttgctgttaa tttgaaatat tcaatcgttc cttttgtttg
     6121 ctcgtttatt ggtgctggtt ttggtggagc atttatgaaa atttttgatg taaaagccat
     6181 tggacaagga ttgactgtat tgccaggtct gactattgct aatccagttc ttccttatat
     6241 atttggtaat ctcatagcat tcattttacc aatcattttt attctcgctt atgataaata
     6301 taaagtgttt atccctgaag ctaaacaccg taaatttgca gaaaaaactg actcaaaaaa
     6361 attgccagtt caagtaaagt gagatgagag catgttaaat ttttttagaa aaaatgaaat
     6421 aagcgttgta gcacctgcaa ccggtgtttt tgaaaaactg gagaaattaa gtgatccagt
     6481 cttttcaaaa ggaatgatgg gacaaggatt tgcaattgat gcaaaaaacg aaacgattgt
     6541 atctccaatc gatggttttg tttcaagtat ttttcctaca aaacatgcct taggaataaa
     6601 aacaaaatca ggaattgaga tacttgttca tgtaggaata gatacagttg agctaaatgg
     6661 tgagggattt gatattaaag ttcaagaagg acaaaaagtt aaggctgggg atattcttat
     6721 gaccattaat tttgtagttt ttgaaaagaa tcacaagact aaagatgtca ttgttgtttt
     6781 tccagactac caagacgaaa ttttcattcc gaaacttgaa gaagtaaaac aaggacaaga
     6841 attgtttgtt cttggctaat gataagtaat taataataga atcgaggaaa atgtatggtt
     6901 tttggggcta ttgaagctgg tggaacaaaa tttgtttgtg ccattggaga taaagatttg
     6961 aacatatttg aaaaagtcag ctttcccacg actacaccca aagaaacaat gaatttagtt
     7021 ttagattttt ttaatcatca taaagatgat ttagaaggta tcggagtggg atcgttcggt
     7081 cctattgata ttcattgtga atctaaaacg tatggcttca ttaaatcaac gccaaaactt
     7141 gcttggcagg attttgattt tattggaagt ttaaaaaagc aacttaatat tccaactgct
     7201 tggacgactg atgtaaatgc ctcttgctat ggtgaatatg tttctggaaa tggcagaggc
     7261 ctttcaagtg ttgtttacta taccgtagga acgggcatag gaggtggcgc tatccaaaac
     7321 ggaaacttca ttgaaggttt tagtcatcca gaaatgggac atatgcttgt aaaacgacac
     7381 aataaagaca acttttctgg gacatgtcca ttccacggag actgtttaga gggcttagct
     7441 gctggtccgg caatcgaaag aagatcaggg aaaaagggac aagaagtgac tgaaaatgac
     7501 gttacttggg aaatagaagc ttattacatt gctcagtgtg catataatac aacattgatg
     7561 ttatcacctg atgtcattat atttggtggc ggagtaatga aacaaaaaca cttaaaaaag
     7621 aaagtacaag ataagtttat tgagttgatc aacggatatg tcgctattcc cgatgttgac
     7681 aattatatta tgacaccaaa attgttagat aattctggta ttgtaggttg tttagcttta
     7741 gcaagagacg ttaaagaaaa atcttaattt ggaaaaaaga tcgtctcgac tatttgtttg
     7801 gttgatgcga tctttttttc aattagtaat tgaagggacg cctaaaagtg aaaaaaaaaa
     7861 tgaaagatga agtattagag tatatcaaaa ataatttaaa gtattacgat ttttctgctc
     7921 aagatattgc aatgaaattt tgtattaaaa gaaatgtcgc ttcccactat ttgaatcagt
     7981 tattttcaga tggaaaatta ctaaagaatg attctgttag accagtaatg ttcaagtata
     8041 atcaacaaaa gccaaaagac tgcttttcta agtttattgg agcagacata tctttgaaat
     8101 ccactataga taaatgcaaa gctactgtaa tgtatccccc taatggcctc ccattaataa
     8161 taaaaggaaa cagtggcgtt ggaaaaagtt ttttagcaag tttgatctat cagtatgctc
     8221 ttgatagaaa agtaattcat aatgacgcaa aatttgttgt tgtgaattgt gcagattatg
     8281 caaataatcc agagctattg tcagcagttt tatttggata taaaaaagga gcctttactg
     8341 gggctgaaaa agatactgca gggatgctat cttctgctaa tggaggatac ctttttttag
     8401 atgaggttca caatctaagt gcagaaaacc aagagaaatt gtttcttctt atggattctc
     8461 aaaagtatcg taaacttggt gaaagtgtgc aatgggagta tgcaaatgtt cgccttatct
     8521 tagccacaac agaagataaa aatacctctt tgttagcaac ttttagaaga cgcatcccag
     8581 ctgaaatcac tctgccagat tacaataata gaagtacatc tgaaaaaatt caattattat
     8641 ttgaatttct taaagatgaa gcaattacga ttgattcaaa aatattttgt tcgattgaac
     8701 tttttactga tcttttatcg aaaacatttg aaggaaatgt tggagaattg aggaatgaaa
     8761 tcaagcttct ttgtgcagaa ggttatttag gaaataagag aaagtcttca atttatttag
     8821 gggacaaact agacagcggt ttttggatag atccagaaat tagtatagat ttaaaaaaaa
     8881 tgtttcttaa atcactttct gaaattgatt tgattgaact ttttcaaaat cacatttcaa
     8941 ttgaagaaag catgagtcaa ttaagagata gaatacttaa agagtgtgca ggttcttctg
     9001 agtataatta tttagaaagt gacgaattta tagcattaag aaactatgtt gttaataaaa
     9061 tatcaccaat tattgattcg acaggtctat gtttattaga tgaattcttg gcggatatca
     9121 gtctatttat aatgtttatt gatgtaattg aagaaacatc aagaaatttt ttgctgtcta
     9181 agttcagaaa atttcgtatg aaaaatgata aacaaaaatt attggcaaat gagatttgga
     9241 gtagtttaga agtcgaagaa agtaaacaag aacttttgtt gaaatggata ctttttcttg
     9301 taaagaagtt ctatgtgaaa ataccagaaa cccattgtct gatagttatg cacggtaaaa
     9361 taacagcttc tgcgatcgca agggaaacaa ataagttgct gaatacatat gtttatgagg
     9421 ctttcgatat gccaattgaa ggtgagacta gtgacttaat taacctaatc aacaattttt
     9481 gtaaaagtat agatacgacg aatggactca ttctgctagt tgatatggga tcattggaac
     9541 aaatgtatga aaaaattgaa tccaatgtaa taggtgattt ggtaatttta aacaatgttt
     9601 ctacagcttt agcgattgaa tgtgggattc aagtttgcca aaaaaagcca attagtcatt
     9661 tttaccagat ggattttgat tcgtttcaag ttaaagttca gtattataaa ggattatcac
     9721 aaaagaaaaa tgtaatagta tcttgtctct ctggtgaggg gatttctgaa aaagttaagg
     9781 atattttaaa acggtatctc gataatcaag tggagatttt gatttttgat tttaacgcat
     9841 taaagaaaat agcaaagg
//
LOCUS       DAFLVO010000089         9600 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.091, whole genome shotgun sequence.
ACCESSION   DAFLVO010000089 DAFLVO010000000
VERSION     DAFLVO010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.091"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            112..306
                     /locus_tag="L1U99_002477"
     CDS             112..306
                     /locus_tag="L1U99_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212998.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            575..874
                     /locus_tag="L1U99_002478"
     CDS             575..874
                     /locus_tag="L1U99_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1212999.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(971..1405)
                     /locus_tag="L1U99_002479"
     CDS             complement(971..1405)
                     /locus_tag="L1U99_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1213000.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1637..2347)
                     /locus_tag="L1U99_002480"
     CDS             complement(1637..2347)
                     /locus_tag="L1U99_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBN1213001.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2337..3197)
                     /locus_tag="L1U99_002481"
     CDS             complement(2337..3197)
                     /locus_tag="L1U99_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HBN1213002.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3202..3840)
                     /locus_tag="L1U99_002482"
     CDS             complement(3202..3840)
                     /locus_tag="L1U99_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBN1213003.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3855..4154)
                     /locus_tag="L1U99_002483"
     CDS             complement(3855..4154)
                     /locus_tag="L1U99_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1213004.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4197..5681)
                     /locus_tag="L1U99_002484"
     CDS             complement(4197..5681)
                     /locus_tag="L1U99_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBN1213005.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5701..6162)
                     /locus_tag="L1U99_002485"
     CDS             complement(5701..6162)
                     /locus_tag="L1U99_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1213006.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6180..7247)
                     /gene="ulaG"
                     /locus_tag="L1U99_002486"
     CDS             complement(6180..7247)
                     /gene="ulaG"
                     /locus_tag="L1U99_002486"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HBN1213007.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7465..8235
                     /locus_tag="L1U99_002487"
     CDS             7465..8235
                     /locus_tag="L1U99_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBN1213008.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8508..9335)
                     /locus_tag="L1U99_002488"
     CDS             complement(8508..9335)
                     /locus_tag="L1U99_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1213009.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
BASE COUNT         2993 a         1955 c         1501 g         3151 t
ORIGIN      
        1 aaaactttca aattgattct ttttatttat cataaagata tagatacata atcattttca
       61 cttacatata tttgaatatt aactaaaaac agcaagaaag aagaggatca aatgtattat
      121 gtagaagtaa aaacaaaagg cgtcaaaaac aaacaatatg tgaaaggtat cagtaacgaa
      181 tatcctttac ttggttcatg gaaagaagct gctccttttt ccaaaccatg tgccataaaa
      241 ataaagaacg agctagaaaa agaactgact tgtggtaaag ctgttgtaga tatcatcgaa
      301 aagtaaatcc aatgtataga aaggaagatc acacatgaaa agcgacgtac aaattgctaa
      361 gattatagaa ttagaagaag aagacgcagt gttgacaatt gaaaaaaaat aaatgtttgt
      421 ataccatatg attatttcaa tatgtatcct ggaattggag atctcgtaga gctatatcaa
      481 gatgaatcaa atatacttgt cattcatcat gaaatataga gacttataaa attgtttatt
      541 tttataatgt atcagtatag aaaggaaata aaacatggat tatactgttg aatttgacag
      601 tgaactactt aagcaatttc cacaagaaga acatttcatg tataaagaag caatttccca
      661 caaagtgaca gagtatttgg agcataattt ttttcgtata aagccagtgc gtactcgttc
      721 ggcaaaagga atatacgaga tgaaagtcaa aattaataaa aaaaattatc gcatagcatt
      781 tgctttaaaa aaaaatcatg tgttcatttt ttatattagt tcgaatttgc aaaaaattgt
      841 atttgataaa gaggtgagta aaaaaataaa atagctgagc attggaggat agattgagtg
      901 atactaagtc tatcctcttg tttttctaaa gaactaagct agaatttttt cttttgtacg
      961 ttattatatg ttatttgtca ttaccaaaaa gcaccttttt tcttctagta tctatgacat
     1021 aagaaatacc acccatttcc tttacttgaa caaatcctac tgattcataa aatttttttg
     1081 ttttctcagt atcatctgtc aataattcga tttggactgg tccataacta gtgatcttct
     1141 ccaaagcttc attcaaaagc actttgccta ttccttggcg ctgatacctc ggatgaatga
     1201 ggatatcttg aataaatgcg atcgtcgcaa aatcagtgat ccaacgaacg attccgataa
     1261 tcttcccttc cccattacgc tttatcagag attcagattg ttcaaatgct ctagctaacc
     1321 ttgcagtgtc ttttgtgtaa ttcgtccaac caacgctctt atataattca gaaatctcat
     1381 cgatcataag ggaatcaata ttcatttttt tcttcctttc ttatacaatt ctccctctaa
     1441 taatacagtt ctttgactat ttaatctatc acatataact ctcctgtaaa gattctctcg
     1501 attccttaaa attcctcttt ccttttagaa tgcatacttt ttgataaata aaaaggttgt
     1561 gataaatttt cttcacaacc tctgtttctc tctatcaagt gttatctttt aattttctac
     1621 ccttacccta gcatctctat tgcccgtagt atgcatactt tccatgtttg cgaaaataat
     1681 gtttatctag taaatattgc gggatttcac atatattggg gttgatcagc tcgttttctt
     1741 tggccatcag acaaatttca tctaagatca aactgttttc tactgctttc ataggtgaat
     1801 ccccccatgt gaacggtcca tgtccataga caagtactcc agggacttcg tttggatcta
     1861 attttctttc cttaaacgtc tcgacaatca cattccctgt atgaacttcg taagcttctc
     1921 ttacttcttc tttcgttaat tggcgtgtac aaggaacctt accataaaaa gcatcagcat
     1981 gagtcgtgcc ataagctggc aaatcgcgtc ctgcttgcgc ccacatgacg gagtgcgtgg
     2041 aatgagtatg agtaatagca gttatatctt caaaagtttg atacaaaaca acatgtgtgg
     2101 ggagatctga agatggtttt aagctatctt cttctattat atttcccgac aaatctgtta
     2161 ccaccatttg atctgcttgc atgcattcat atctgacacc gcttggctta atgacgatga
     2221 ctcctagctc acggtccact tcactcacat tgccccaagt caatttgact aatccgtatc
     2281 gcggcaatgc cagatttgct tcaaggacac gttgcttcat tgctgcaatt ttttcttcac
     2341 aagacatcat agccagcctc cttcaattta gaacttaagt agtcttttgc ctgctggatt
     2401 tctcttcgaa agtcttggct tttttcactc cacatttcaa tcagaaatgt tccatcataa
     2461 tctagacgtt tcaaatgtct taataatcca agaaaatcaa cacaaccgct accaaaagga
     2521 acatcacgaa actggcctga atattctttt gttacagggt aagtatcttt taagtggata
     2581 gcagtgatat aatcgatccc tttctcaagt tctcgagccg gattattttc cggccatgcg
     2641 gacaaattgc ctaggtctgg atatacttgt agaaaaggtg aatgaatctg ttctttgatt
     2701 tctaaaaatt ttgaaatgga gttcataaat ggatcatcca tgatttccac ggaaagaatg
     2761 atgccatatt tagaagcttc ctttacgctt tcttttattc cttcgataaa gtcttctctg
     2821 gaattcattg atttctcttc ataataaaca tcgtatccag ctatttggat tactttgacg
     2881 cttagattat gcgccaaatg gattgctttt ttcattagtt gtttcgctgc ttttttcttt
     2941 tctggatcag cagaaccaaa cggaaatcgc cgatgcgcac ttaaacaaat cgaatggata
     3001 cgtacaccgg agctgaacat ctcttctctc agctcagcta tcttttcttc agaccaatct
     3061 aatcgtgcta accgctcatc cgtctcatca atcgacatct cgataaaatc gaagtccatt
     3121 tcttttacaa gggaaaaacg ttctttccat gaaatatctt tgggtaacgc tttttcataa
     3181 atcccaattt gagccatttc cttaccccca gatacgaatg atctcatctt tgaagttttg
     3241 tgcggccttc atcggatcat ttgctgctgt aataccacga ccagtgataa aggtatacac
     3301 atcgatccct tcaaataagt gtaatgtgtg tggatttaat ccaccagtta cagaaacatt
     3361 aaagcctagt tcaatcagtt ttttgatctt cgataaatct ttttcacccc aagtttcacc
     3421 agataacagc gcatcacggc tttgatggta gattacctgc cggataccga tgttatgcca
     3481 atccatggct tgttcaaaag tccaattgcc gtagagttct acttgcaatt cacctatttc
     3541 tttttgtgct gcctccatag ttggaatcgt tgcacaacaa atgactgtca tccagtctgc
     3601 tcctgctttt gcaacattac tcgccactgt tcctccagcg tctgcacatt tcgtatcagc
     3661 gactagtttt ttatctggga acatactgcg aatacagcga atcgcttttt gtccttcctg
     3721 taagcaaaga attgtgccca cttcaataat atctactaca tcaccaactt tcataacatc
     3781 tcctaatgca tgttctaagt cattgtgatc taacgcaatt tgcaaattcg gcctgctcat
     3841 cttagttcct tcctttactt gtttttttgg taccactttg tttcagcaaa tttttcactg
     3901 atttctttga ctgacatcac atttttgata ccgataactg taactccttt tttctctgcc
     3961 tgagtaaaca tattcaaaaa attgactggc gtaaaaacta catcgtattg gccagctgaa
     4021 ctttttccct ctgaaatggc acaatgatgg attttggtaa ttggtacgtt tagttctttc
     4081 attgcttttt ccacacttct catcatcatc aagcttgttc ctgatccatt tgcacacgat
     4141 actaaaattc tcatcttaat ccctccatta tgagtgttgt ctaatcagat tttcttttat
     4201 actctctgct tttctgcata tgtgtcatag tcttctacaa tcaaaaaata accatcagga
     4261 tttttccgat attgtaactg cggaatagcc aataaaccaa tgacaactac ggcaattcca
     4321 gcataaccta ggactttcat gattactgta aacaatggcc aagctgttgc ccagtcgaac
     4381 atcccgatat aaccaccgta tgttgacatc ccaatccatg tagcgaataa tgctgaaccg
     4441 cctacttgta tgattcctga aagaaacggg aacaggcaag cggctttgaa tccacctcgg
     4501 ttattggcat aaactgctat aacggcatta tcaaagaaca acggaatgaa accggctatg
     4561 acgatcgttg gtgatttcaa taaaatcagt aaaccaatca tcaaaaactg tcccaaagca
     4621 ccaaacaaga acccaatcgt taccgcattt ggcgaaccaa agccaaaagt agcagctacg
     4681 tcaattcctg gaacagctcc tggtaaaatc gtgtttgaga ttccttggaa agattgagtt
     4741 agttcatcga cgaatgtccg aacacctaat tgcaagatcg ccagatatac cgcaaaattt
     4801 aaagaagtcg tcataatgta gaataagaaa ctctgccctt cttgcatgaa ttgcgcttga
     4861 atcaaataat ctttgcctag tacaatcaga atgatcccaa agaaaaatag catgagtaac
     4921 gaagtagcaa ccatattctc attgaaaatc gacaagaatc ctggtaattt gatatcttca
     4981 atttttttgt cttgcttgat tgatctattt ttcttttcat cccgcttttt catccactca
     5041 gctaattttg caaatataaa gattccgaac atttgctgat gtgccactgc aaatccggca
     5101 ccttctgtca attcctgcgt gattcctact gttaagttag aagctactgt ccaataacaa
     5161 cctaaaatca gtcccataaa aatcaatgct tgtatcctac ctagatcagg aaagcaaaac
     5221 agtaaaatcc aaaaagcggt agctgcttgt tgaacctgaa cgtttccggt agtgaaaacg
     5281 gaacgcagtt tcgtatattt ctgaaaacgg actaataaga tatttaaaac aaatgcaatc
     5341 agtaataaaa tcatcacatc tccaaaggta cggccaaatg tctccattaa tccagcatcc
     5401 acagcatttt gtccaaaata aggatctgta accatggcat ccaaattgaa ccgttccttt
     5461 agtccaacca agattggccg aaaattattg accaaaccac cagagccaac agtcaaaata
     5521 aagtaaccga ccgttgcctt taagaatcca gcgatgcatt catgaagcgg gcgtttcagc
     5581 aaaatatagc ctaataacac gataaaacca atcaggtatg ctggctgcgt caagatattt
     5641 gttgcaaaat acgtccaaat gcttaacaaa aattccccca tcttttttct cctctatcaa
     5701 ttaattatat tctgccatca caacttggta atcatcgatg gagttcgtag agatgagacg
     5761 ctcaaccaat ccatctgtca ttaataattc ggataatttt tggatatttt ctagatgttc
     5821 ttctggatct tttgctgcga gtgtaaaaaa caaactagcc gttttctcct cattctcccc
     5881 ttcactttca aaacggattg gctgtttcaa cttggtaaat gaaatagctg ttccaaaaac
     5941 accatcactt ttttctgaag aatgcggcat tgctacttga ggtgcgatca caatataagg
     6001 accgtatttt tctacacaat ggatgatctc ctccacatac gtttcatcaa taatttcctt
     6061 atcgatcaat acaagacagc tttcggcgat agcttcacgc caatccgtga tttctttatc
     6121 tgggtaatga atcaattgat ggtcaaaaaa gtatttcagc aagaaactcc ccttctttct
     6181 tataaaaacg acggaaacgg tgtatcattt tcaatcgaga agacatcttc aaatcctcga
     6241 taaaaattaa actcaagatc atctttgttt gtcggataga tgaatttccc gcctacttgc
     6301 cagatataag gtttaaatcc atacttcagg cgatcctttt tgaatttcca aatttcagtg
     6361 atctcttttg gatcagccat aaaattagac caaatatcgt agtggacagg aatcactact
     6421 tttgcattca atgactccgc catgcgcagc atatcaacag aagtaacttt gtctgttatc
     6481 cctcgtgggt tttcaccata ggcccctaaa cagacatcga ttttgtgttc attaccatgt
     6541 ttggcaaata aattggagta atgtgaatct cctgcatgat aaagattccc tcctgatgtt
     6601 tcgaataaat agtttactgc aatttgatcc atctcctgag gcatttttcc ttttaatacc
     6661 tcttctggat cttcacaagt gaccaacgct gtccgatcaa acgcttctaa agctactaca
     6721 ttgatgtctt tgattttgac tgcatcacct ggctttactg taatcgtttt ttcttcagga
     6781 attccccatt tttgccacgt gcgaaccact tcttttggcc caatgaatgt tgcttcagga
     6841 caattttgat gaactgctgc ggctgtatgg atatctagat gatcggaatg gatatgtgta
     6901 acgattaaag cgtctacatt ttttatcgca aaaggatcga ttacgaaagg ctgagtacgt
     6961 aaattaggct gcatattttg aacgccactc atacgcatca tctgatggcc ttttttcatc
     7021 atgccattcc catgactacg ttttcccgtc ccacaccata gatcacataa aatattcgtt
     7081 ccttcatgac ttttcagcca aattcccgta cagcccagcc accacatagc aaaagttcca
     7141 ggatccacta cttctgtttc gatttcttca ttcaagtatg tgccccactc aggaaatgtt
     7201 tctactaacc acttttcttt tgttacttca ttgacagttt tactcatttg cttgctcccc
     7261 ccatatcgtt gttccaactt acaagtaaat attaatgtgt atcagcatcc atgaaaaccc
     7321 ttttatatga ccgtttgttt tttatatgat tttctttcag taatcaatga ttgtttcagt
     7381 ataataaaga cagatatgaa tgtttaaatg aacaactagt caaataaatc catggatcaa
     7441 gatgtccctc aggaggcaaa agtcatgaaa aactcacttg tcaatattga aaaacgtcaa
     7501 aaagaaattt tggaactgct tcagcagact gaacaactat caactttcga attagctgaa
     7561 tcccttgatg tatctattag tacgatacga agagatttaa atttattaga agaaaaaaac
     7621 gagatcatac gcaattacgg ttattgttct tataattaca aaaaccagac tgattttgat
     7681 caatctggtc ctgaaaggat taaacaagcg attgccagag aagctagtaa atacattaac
     7741 gattatgata cgctgtttat caattctagc tcgactgcgt tgaaaacact ggattttctt
     7801 caatctaacc atttgacagt cattacaaac aacgtgaaaa tcaattactc tccgcacaaa
     7861 gataattgta gttatatttt aactggtgga gagatgcgct ttccaaaaga agcactagtg
     7921 ggcgacatcg cattaaatac gatttcttca gtcaatgcag acatttgtat cattggctgt
     7981 agcggagtcg atgtagtaca tggggtcaca acaaagatat taaatgaatc aacgatcaac
     8041 gaaatgatgg tcaacaagac aatcaaatgt aagattttag tcgctgatca tcgaaaaatc
     8101 ggactgacat caaagttcaa gattgctgat atttcagtct ttgattattt gatcactgat
     8161 aaattttgtt ctgaaaaagt attagaggag atcagaaata cggggataaa aaccattcaa
     8221 gtagattcat tttaagaacc aggacgtaaa tatgtaaata ggattatcaa aaaaatgaat
     8281 aacaaattta tcgataaatg aaaaacacgc tacgctcaaa ttgataaagg aatcccaaga
     8341 tgtatccatc caatcgatac catcataatc tattgcttct tttataaccg ttatatgttg
     8401 cctaaatagg aatcaaacaa tatcgaaaaa aggaggtatg acaaaagtca cacctccttt
     8461 tttcgaataa acggtattca aatcagaaca ctgatttcac aaccacttta tttcaggtcg
     8521 ttttcaatca cctttaccgc gtaatcattt ccgttgaaac gcgctatttt ttttgcgtcc
     8581 atatatcttt ctaaataatc atcttctcct aattgcttat ggcaagaagc aatttcataa
     8641 agcaagtatt ccaatgcata agtcgattta tgtttcttat tatactcaat acccttctca
     8701 cataattgga ttgctttatc ataatcctcg attttacggt aataggtggc gatatcataa
     8761 tatacaatgc agaccatcag attatcaaaa tcagtctcac tcaatatttt aagtgtacgc
     8821 tccacataaa ctttcgcaaa atctaattct ccttttgaca agtagatcat tgccacgttt
     8881 gcagctgctt gtaagtgatg gatatctgtt tcggtcgttt gttccaacac ttgattaaaa
     8941 taaaataatg ctgcatctgg ttttttcgca taaagatgat caagcagtcc ttgataaaat
     9001 aaaatttgat ttaaaagatc agaattactt actttttcct gatcgatcgt ttgtaaaatt
     9061 ttataagatt cttggtattt tgatacagaa ttcaatgatt gaatctcatt tatttttttc
     9121 ctgattttgt cttcttctgt ttctactaat atatcggaga tctcgacatt cagctttttg
     9181 caaagcgcac ttaagatatt gatgcctggc gacatattct tgttttcgat attgctgaca
     9241 gttgcttgtt cacaaatgcc ttctgctaat tgtacttgtg ttaacccctt tttctttcgg
     9301 tattctttta gtaatgctcc atctacttta atcaaaacaa tttccttccc tttaaaaaat
     9361 tatttctcct ttatatcata cacaaaaaaa agttctaaac aaccaaaaat gtttagaaca
     9421 gaataaaaat tttaatttta aaataatatt caaattaaac aactggcgta tctgctcctt
     9481 gatttctttt tgtgttatct gaataattat cgtttacagt tataacacat agtgaaaatt
     9541 gtcatggcga gaaagtctaa gaatattttt aaacataact atttctttct tacgtgtgta
//
LOCUS       DAFLVO010000090         9521 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.092, whole genome shotgun sequence.
ACCESSION   DAFLVO010000090 DAFLVO010000000
VERSION     DAFLVO010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9521
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.092"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            119..1108
                     /locus_tag="L1U99_002489"
     CDS             119..1108
                     /locus_tag="L1U99_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBN1213010.1"
                     /translation="MRDKEMRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAG
                     QYLFDKELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGA
                     MTICLSNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWET
                     CLNEFDKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFME
                     MQWINSNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVL
                     DQADFDLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1090..1551
                     /locus_tag="L1U99_002490"
     CDS             1090..1551
                     /locus_tag="L1U99_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBN1213011.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            1601..2065
                     /locus_tag="L1U99_002491"
     CDS             1601..2065
                     /locus_tag="L1U99_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1213012.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2079..2828
                     /locus_tag="L1U99_002492"
     CDS             2079..2828
                     /locus_tag="L1U99_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1213013.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            2828..3658
                     /locus_tag="L1U99_002493"
     CDS             2828..3658
                     /locus_tag="L1U99_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1213014.1"
                     /translation="MENSTEKKRLITKKDLNKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTSFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            3658..4305
                     /locus_tag="L1U99_002494"
     CDS             3658..4305
                     /locus_tag="L1U99_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBN1213015.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(4403..5179)
                     /locus_tag="L1U99_002495"
     CDS             complement(4403..5179)
                     /locus_tag="L1U99_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1213016.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLAESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
     gene            5323..6282
                     /locus_tag="L1U99_002496"
     CDS             5323..6282
                     /locus_tag="L1U99_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1213017.1"
                     /translation="MTYTHLTTDELVIIESYFNIEKPVALVAQSLNRSRQTIYNVYSF
                     LKQGKKVLDYYRQYKQNKSRCGRRSTVLSDEQSTYVQEKVAQGWSPDVIIGRGEFPID
                     CSVRTLYRMFKKGLFDTQSLPMKGKRKPNNHQEKRGKQAFRRTIHERNSLYPHLTKEF
                     GHLEVDTIVGVKHKSAVITLVECLSKVIITLKPTGRRAEDIENRLNDWFKSMPKHLFK
                     SMTFDCGKEFSNWRSISNSNDIAIFFADPGTPSQRGLNEHSNGLLRRDGLPKTMDFRD
                     TDETFIQSVASKRNHIPRKSLNYRTPLEVFLSCIDKDILSSLI"
     gene            6399..6707
                     /locus_tag="L1U99_002497"
     CDS             6399..6707
                     /locus_tag="L1U99_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBN1213018.1"
                     /translation="MFQNKGQRYVTKGVMDSLPVELQALCWNLIDQNVQKQFHLDYLQ
                     IFEFSTEKGNQKLVHRQEEPEARKEYLISPKLRLKSVSQKIWVIDSGEYQTMLLPEEY
                     "
     gene            6734..7033
                     /locus_tag="L1U99_002498"
     CDS             6734..7033
                     /locus_tag="L1U99_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HBN1213019.1"
                     /translation="MLETAIEVLEKCAQLVTTPEEWGYESVTMEKEEIEMGMLPEDVT
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTNE"
     gene            7207..7758
                     /locus_tag="L1U99_002499"
     CDS             7207..7758
                     /locus_tag="L1U99_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HBN1213020.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFPRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            7904..8197
                     /locus_tag="L1U99_002500"
     CDS             7904..8197
                     /locus_tag="L1U99_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213021.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            8190..8486
                     /locus_tag="L1U99_002501"
     CDS             8190..8486
                     /locus_tag="L1U99_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213022.1"
                     /translation="MAKLIVLGGLIYGGYWLYKYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHAGYRHSWERIN"
     gene            8557..>9521
                     /locus_tag="L1U99_002502"
     CDS             8557..>9521
                     /locus_tag="L1U99_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBN1213023.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKETVETDTTIEAKKSKTQS
                     TEQTTTEMKQSVEASTSESSIIESSSEEVKNTLWDSEKSTQLAIFVPQWGKTLGQEYK
                     SYNPQNNVSLYGTPLPSAVIDGNWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVET
                     GEYLGQHVYFFGFQNGQPKVYLTQQNQGNDKNYMYFNETQNQQLKQGFIDIVNGQTPQ
                     TPVVEESTQQATTTTTQSTSSSAISSWEAAKETVLNNKALWLYDSPDKNASNTNLIST
                     NEYMKDLMQDENGSYYSINIVTDDNGNTTMAGGKQFRVYTDGRIS"
BASE COUNT         3365 a         1366 c         1785 g         3005 t
ORIGIN      
        1 cattttatta tataaaattg ttataaaaaa atttttttga aaaatagtat tgcaaaataa
       61 agcaatttca tagataatag gtattgtaaa gttatatgac tttataatac ttattagagt
      121 gagggataaa gaaatgagac aactacacaa agaacagatt gaaacagcaa tggcagcgtt
      181 aaaggaaaag acaattgatc atgtatattt tacagcatgt gggggttcac aagccgtttt
      241 aatggctggt caatatctat ttgataaaga attaactgta ccttgtcatg tttatactgc
      301 taacgaattt aactatgcta taccaaaagg attatctgaa aattctttag ttatcacttg
      361 ttcccattct ggcacaacac cagaaactgt agaagcaaca aaaaaagcaa gagaatttgg
      421 agcaatgact atttgtttat ctaatgaaga aggatctcct ctatgggaag cagctgaata
      481 tcctgttcac tatgattggg gtaaagatgt tgatgctagt gatttaaata aaggaattct
      541 ttatggttta ttatttaata ttttacttgt tttagatggc tctaaaaaat gggaaacttg
      601 cttgaatgaa tttgataagt taaatgatct tgttattgct gaaaagagca aatttgaaat
      661 aactgctaaa gaatggggta aaaaccaaaa acgagataaa attatttaca caattggtag
      721 cggtatcaat tacggagaaa tttactccac agcagcttgc tggttcatgg aaatgcaatg
      781 gattaattct aatgctattc attctgggga atttttccat ggtccttttg aaatcactga
      841 ttatgatgta ccattcatct tagtgaaaag tattggagat acaagatttt tagatcaacg
      901 ggtagaagac ttcactaaaa aattcagtaa taaattaatg gttttagacc aagctgattt
      961 tgacttagaa tctatagata gtgtagcgaa agaatatatt gcagctgtac ttagtggcgt
     1021 tgttattcgc caaatggtag aagcgattgc ttttgaaaga ggccattcct tagatgttag
     1081 acgctatatg tggcaaatga aatattaatt aataggaggt tgcaaaagat ggcaaatcaa
     1141 ttatttcaca ttgtgattac aacacattct accctttgtg agggttattt aaaggcaaca
     1201 aaattaattt taatgaatga cgccacaggt attagtgctg ttccatttaa agaaaatact
     1261 agtccagatg attttgagga gagtatgaaa gaaataatta gtcagcatca tttgcaacct
     1321 ctaattattt taacggattt aattggagga acacctaata atgtttctat taaacagttg
     1381 aacaacaata gaattcaaat tattgctggg attaatttac ctcttttact ggagttatta
     1441 atggcccagt cagctggtaa atctatagaa gaaatagatt ttaaggaatt actgaataac
     1501 tctcaaaaaa gtatggttca tattaattcg cttttaaaag atgtcagtta aggtggcaat
     1561 ttctattcta taaattttaa aaattgaagg aggaaataga atgattaaat tagtgcgtgt
     1621 agaccacaga ttacttcatg gacaagtaat attttcttgg actaaacagt atgatattaa
     1681 ccatattatt gtggctgata acaaagttcc aggagatcca atgtctgtga tggctttgac
     1741 aattgctaaa cctgctgatt gcaaattaga cattgttaaa attagtgatg ttaaagggat
     1801 tatggaaaca tccccaaatg ataattacat gattttaatt aaaggaccta aggaagcttt
     1861 tgaattagtt caaaatttac cagaaattaa agaaattaat tttggcggtg tgtctaagaa
     1921 aagcgagtcc aaacaatatg gaaaggcagt ctttttaact cctgaagaat tagaagccac
     1981 aaaaaaaatt cttgatcaag aagtgaaaat atttgtgcaa caagtcccat cttcaagtat
     2041 tgaaaatgta gattttagta agtaaggggg gaaaataaat gttattaaaa gccattttat
     2101 taggtttagt tggtgtggta gctgttattg actccaggtt aattggtcga caaaatattg
     2161 gtagaccact aattttgagt acacttgccg gacttgtgct aggtgacttg catacaggga
     2221 ttgttcttgg ggcatcttta gaattaattt ctatgggatt cgtctcaatt ggggcggctg
     2281 gacctcctaa tatgcaactt ggtagtatta ttgccactgc ttttgcaatt ttaactaata
     2341 gtagtacaga aacagcctta acaatagcta tcccagtggc tgtagctggt gaatttatga
     2401 gtattatcat gcgcatgata attgctcaat ttggacatgc tgcagataaa gccattgaaa
     2461 ataataaatt tagaaaagct caaattattc atatttattg gtcatttatt tttaatgctt
     2521 ttgtttactt tattccaatc tttttaacag tatattttgg tgctgacgtt gtggcagatt
     2581 tagtagataa aattccagaa atgattacag acgccttgac tgtctctgga aatatgcttt
     2641 ccgcattagg gtttgcaatg ctattaagca caatgttgag taaaaaatta tatccttact
     2701 ttatttttgg attctttatt gttgcctatt caggtctttc actaattggc gtgacaattt
     2761 ttgcagctct gattgccttt gtaatggatc aagttaaata tggaaaaaga gaagaggcgc
     2821 atggttaatg gaaaatagta cagaaaaaaa acgtttaatc acaaaaaaag atcttaataa
     2881 gatgtgtctt cgttcatgga caatcatgtg ttcgtggaat tatgaaagac aaatgcatat
     2941 gggatttatg tatgggatgg cgccaatttt aaataaagtt tataaaaatg atgaagagaa
     3001 aaaaagagaa gcttatactc gtcatatggc attttttaac tgtacgcctc aaatgacttc
     3061 atttattatg ggactttgtg cttctatgga agaacaaaat gctcaagcag aagaaggaaa
     3121 ctttaatact gaatctatct ccatgattaa aaccagttta atgggtcctt ttgctggaat
     3181 tggtgattca tttttccaag gtactttaag aattattaca tttgggattg gattgtcttt
     3241 tgctaagcaa ggtagtattt taggaccgat tttagctgtt ggcctttttg ctataccttc
     3301 tattttagct gttttttacg gcggtaaatt aggatatgag tctggcaata aataccttac
     3361 taaattgtat caagaaggtc ttatggatcg agtaatgcaa tttgcttcta tcattggttt
     3421 ggctgtagta ggtggaatgg tggctagcat ggtgccaatt gtcacccctt taaaattcac
     3481 tacaggggga acagaacttg ttttacaaga cttacttgat tccattattc ctggattatt
     3541 accacttgta tgtactttgg gaatatataa attgattaag aaaaatgtta gtacaaatat
     3601 gctcttatta ggttgtattt tggcagggtt tgttttaagt ataataggta tcttataatg
     3661 attaaggctc taatttttga tatggacgga gttttaattg atagcgagat tatgtatcaa
     3721 aagtgggtat ttaatttttt aaaacaagaa aatttaagct atcctttgta ttcttatcaa
     3781 aaaaagattg gaactacagc aagtattttt gatgatatag aaaagtacaa tgagggatgt
     3841 aacagtttag aattgaaggg aaaatttact aaatattgga aatcgcaaaa gattgattac
     3901 ttggatattt ttcctaatat actaattgaa cagcttgaat ggttaaaaaa gaaaaaaata
     3961 aaaatggcaa ttgcttcttc cagtccaatg gatactataa atgaagttgt taccacttgt
     4021 aaaatagagt catattttga ttgtttaatt agcggaagag atttgccaga aagtaaacct
     4081 aatcctacta tattccttaa agcttcagaa cagctcagaa ttccagttga agaatgtctg
     4141 gtgatagaag attcttataa tggtataaaa gctggtaaaa gagcaaatat gaaggttctt
     4201 gcaattaaag ataaacgttt ttctcaagat gtaagtctag cagatgatgt tatttacgat
     4261 attaaatatc tgcgacaaga agtacaggtg aaatttggaa tataaataag ttttttgatg
     4321 tatttagaga atattagtaa aaataaaaat catgcccaaa tctaatcaaa attgattgct
     4381 ttgggtatga tttcttttaa tatcaatcta ttactttagg atctgaatca tttttatgca
     4441 ccgtatctaa agtgatattt tctgtgactt caataacata actaattcta tcacaacgaa
     4501 ctgtggattg agaataatga aatggttgat tatttttatc tttgccaacc ttttctaaaa
     4561 taaatagcgg atctcctact atacattgca ataagtcgga aagctcaggt gttgcagata
     4621 aaccgtttat ttccataata gagctcgtag ctttgacatc atagtcatct tctagaagtt
     4681 tatataatga agtatattgg ctaccttttt caaataaagt tggaaatttt tcttctgatg
     4741 cgaaaaaatt atcaattccc atcggggcac cgtcttccca cattaaacgt ttaatattgt
     4801 aaactctatc agttacattg atttgtaatt tattagctaa aaactcatca gcctttataa
     4861 ttttagaatg taaaacagta tatctaattt tatgtcctcg ggtagaaaga gaatcgctaa
     4921 atccatgaac tccagctaat tttaaacttt cttttttttg agttacaaag gtccctttcc
     4981 cccttaatcg ttcaactgtt ccactttctg ctaaaagttt aaaagctttt cgaatggtaa
     5041 tcttacttac tccataaatt ttacataatt cttcttctgt aggtaattgc tctcctggaa
     5101 gatatttttt ttcacgaata tcgttacgta tagaagcttc tacttgtaaa tataatggtc
     5161 tattatcttg aaaattcata gtacactccc taaaaagtta tacttcatta tatcacaatt
     5221 tattaaaacg tcgattgtaa aattaagcta gacaactaaa aagatcattt gtgctacact
     5281 caaaatagtt ccgaccaaag aattaataag gagtgagtac aaatgactta cacccatctt
     5341 acaacagacg aactagtaat catagagtct tatttcaata tcgagaaacc tgtcgctctt
     5401 gtcgcacaaa gtttaaatcg ctctagacaa accatttata atgtttattc gtttctcaaa
     5461 caaggaaaaa aagtgctaga ttattaccgt caatacaaac aaaataaatc tcgttgtgga
     5521 cgacgttcaa ccgttttatc tgatgaacaa tcaacatatg ttcaagaaaa ggtagctcaa
     5581 ggatggtcac ccgatgtgat tatcggccgt ggcgagtttc caattgattg ttctgttcgt
     5641 acactctatc ggatgtttaa aaaaggcctt tttgacacac agtcgttacc tatgaagggg
     5701 aaacgtaaac cgaataatca tcaagaaaag cgtggaaaac aggcctttcg cagaacgatt
     5761 catgaacgga acagtctcta tccacacctg actaaagaat ttggtcatct cgaagtcgac
     5821 accattgtgg gagttaaaca caagagcgct gttattacat tggttgagtg tttatccaag
     5881 gttattatta ctttgaaacc gacaggcaga cgagccgaag atatcgaaaa caggttaaat
     5941 gattggttca aatccatgcc taaacacttg tttaaatcca tgacatttga ttgtggaaaa
     6001 gaattttcca actggcgatc tataagtaac tcgaacgata ttgccatctt tttcgcagat
     6061 ccaggaacac cttcgcaaag agggctaaat gagcactcaa acggcttgct tagacgagat
     6121 ggcttaccta aaacaatgga ctttagggac acggatgaaa cctttattca atccgttgcc
     6181 tcgaaaagaa accatattcc aagaaaatca ttaaattatc gaacaccatt ggaagtattt
     6241 ttgagctgca tagataaaga catattgtct agcttaattt gacaaatcag atagtataaa
     6301 atgaatcaaa ttgaatatca aatatatatt atatccatga agcccaatct tctttaatag
     6361 aagattgggc tatttttatg gcaaaggagg gaaaagaaat gtttcaaaat aaaggacaac
     6421 gttatgtcac aaagggagta atggacagtt tgccggtgga attacaagct ttatgttgga
     6481 atctaatcga tcaaaacgtt caaaagcaat ttcatttaga ctatcttcaa atctttgaat
     6541 tttctacgga aaaaggaaat caaaagttgg ttcatcgtca agaagaacca gaagcaagaa
     6601 aagagtatct gatttcacct aagcttcgtt tgaaatcagt gtctcaaaaa atatgggtca
     6661 ttgattcggg tgagtatcaa acgatgttat taccagaaga atactgatat ctaaaagaaa
     6721 ggaacgaaag gacttgttag aaacggctat cgaagtactg gaaaagtgtg cacagctagt
     6781 cactactcct gaagagtggg gctatgaatc cgttacgatg gaaaaagagg aaattgaaat
     6841 gggtatgctt cctgaagatg ttactctacc acgtttagtg atgacacatc tttatattta
     6901 ttgcgcacca gaagatggaa aagactatgt agtttatttc attacagata ttaccagcca
     6961 gcgagaattt gttcgtgggt tactggtaga aggacgattg gtttggagtc agattggagg
     7021 aacgaatgaa taagatcgat tatttgagaa tgattgcgaa atgtttagaa gatatcctta
     7081 cagcgattca tcaaattctg aagaaaaaag gagaaagaat atgaaatatt ttcaactagt
     7141 attgacactt ataacggcaa tggtgattga attgcttgaa caaaaattag cataggagaa
     7201 aaagagatga ttgaaaaaga attagtgacc acacaaacag aagtttggcg agatcctcat
     7261 catacccatc gctatgtttt caaacgacaa tgggcgatca aaggaaaaga agcggaagat
     7321 aaattagcgg tagtcattac tattcgtcca acagatacag aaccatttac gaatgatttg
     7381 agtatgttat taatcgaaaa gaatatccga caattaggat ttactggttt tattgctgtg
     7441 aatctttttt cgtatacaaa agcgaaaagt cctcgggtat ttcctcgtgg aaatgatgaa
     7501 caatctttgg aaatattaac aactgttttc acagaaaaga aaatcaacac cattattttt
     7561 gcttgtggtt cgattacagc gacgagtcaa gtggcttatg aacaagcgaa gaccatttac
     7621 gatcaattga gtgcgaaaca aaaaaagatg accaaagtat tgataaatgc agaaggtaag
     7681 ttatcccacc cactaagtat tcatgttcgt aatgaatggc aattggcaga tagtcaatta
     7741 ttatttcaag aaaaataaca ttttattttc ttatgttact tataagtagt tttacatgct
     7801 ttttgacttt aaaaatacat gtgatgatac atgttatatg aattatcaat gtacccagta
     7861 atatgctatt ttcattatgt aaaaaataac agggggtgtg tagatggaga ttgatgaaac
     7921 ttgtttgagt aactcttata aaagtatgaa tgactttttt gaggaaatgg aactggattc
     7981 agaattgctc tatcaatttt atcttgcttt tcgagggcaa cagatttctt ttccaatgaa
     8041 aatgtacgat cgtgagttag ttagaaaaag aatcgaaaac atgatagaac aggaaaaaac
     8101 tgtagatatc cgtcaattga cagaagttta tggtttctct gcaagatgga ttcaaaaagt
     8161 aattaaacaa aaagaaagga gacgagtaca tggctaagct gattgtatta ggtggtttaa
     8221 tttacggtgg atattggtta tataaatata tgcttgcgca tccgaatata gataaaggaa
     8281 aagtaattaa gacagttggg gtaatcatag ttggactcat agctctaact aagaaaaata
     8341 atactaatag cccaaaaata atgagaactt atcgctgtag aggatgtgga agggaaattt
     8401 ctactagttt taatccatct gaaagccctc aaggaagaga tcgttgtcat gctggctatc
     8461 gacattcttg ggaaaggatt aactaaatga acaccattga gattaattga ctgataaaat
     8521 aagtacgcga gggagaaatt gaaaggggga aataaaatga aaaaatggtt gttattacta
     8581 attggaatgg ggattttatt cactggttgt acatctgaga atacgaggac taaagagact
     8641 gtagaaactg atacaacaat tgaggctaaa aaaagtaaaa cgcaatcaac tgaacaaact
     8701 acaacagaaa tgaaacaatc tgtggaagca agtacaagtg aaagttcaat cattgaatct
     8761 tcttctgaag aggttaaaaa tactttgtgg gatagtgaga aatctactca actagcaatt
     8821 tttgtcccac aatggggaaa gacattaggt caagaatata aaagctacaa tcctcagaac
     8881 aatgtaagtc tgtatggtac gcctttacca agtgcagtta ttgatggaaa ttggaaaatg
     8941 gcaatcaatg aagcaccagt taccgtacaa tggtcagaag atggaactgg tcatgcagat
     9001 ttcaatttag tagcagttta ttctgatgta gaaactggag aatatttagg gcagcatgta
     9061 tatttctttg gctttcaaaa tggacaacct aaagtttatt taacgcaaca aaatcaaggc
     9121 aatgataaaa actacatgta cttcaatgaa actcagaacc aacagttaaa acaaggtttc
     9181 attgatattg tgaatggaca aactcctcaa actccagtag tagaagaatc tactcaacaa
     9241 gcaacaacta caacgacaca atctacaagt agctcagcaa tttcaagttg ggaagctgct
     9301 aaagaaactg tactaaataa taaagcttta tggttgtatg attctcctga taaaaatgca
     9361 tcaaatacta atttaattag cacaaatgaa tatatgaaag atctaatgca agatgaaaat
     9421 ggaagctact attcaattaa tattgtaacg gatgataatg gaaatacaac aatggctggt
     9481 ggaaaacaat tccgtgttta tacagatgga agaatttctc a
//
LOCUS       DAFLVO010000091         9448 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.093, whole genome shotgun sequence.
ACCESSION   DAFLVO010000091 DAFLVO010000000
VERSION     DAFLVO010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9448
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.093"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(130..777)
                     /locus_tag="L1U99_002503"
     CDS             complement(130..777)
                     /locus_tag="L1U99_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HBN1213024.1"
                     /translation="MEQTIKPYQYFFIKREVDQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILEHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(1056..1559)
                     /locus_tag="L1U99_002504"
     CDS             complement(1056..1559)
                     /locus_tag="L1U99_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBN1213025.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(1682..2446)
                     /locus_tag="L1U99_002505"
     CDS             complement(1682..2446)
                     /locus_tag="L1U99_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBN1213026.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     NAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLADVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            2553..2828
                     /locus_tag="L1U99_002506"
     CDS             2553..2828
                     /locus_tag="L1U99_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HBN1213027.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            3505..4455
                     /gene="yidC"
                     /locus_tag="L1U99_002507"
     CDS             3505..4455
                     /gene="yidC"
                     /locus_tag="L1U99_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBN1213028.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(4634..5608)
                     /gene="lacD"
                     /locus_tag="L1U99_002508"
     CDS             complement(4634..5608)
                     /gene="lacD"
                     /locus_tag="L1U99_002508"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBN1213029.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDTKIPGR
                     LPDLLNIWSVKRLKEAGADACKFLLYYDVDEPAEINVQKQIVIERIGSECEAEGIPFF
                     LEILSYDATIGDPSSLAYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QETCYSQAEASAYFYEQSKVTEQPFIFLSAGVNATLFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATPVYVDR"
     gene            complement(5605..6063)
                     /locus_tag="L1U99_002509"
     CDS             complement(5605..6063)
                     /locus_tag="L1U99_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1213030.1"
                     /translation="MTIIHEENIFLQQPLDSQEEAFKFLAKQTFCLGIALDEKEVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSMIIATLNKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRKAKSKTEIATILTKEIGEDL"
     gene            complement(6060..7523)
                     /locus_tag="L1U99_002510"
     CDS             complement(6060..7523)
                     /locus_tag="L1U99_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1213031.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGIKIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFAGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAMSGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSFDPDHAQYNATAAMVKAVGDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLTILPKQLDGLKAIFLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEHSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLAQGN
                     TTFMAGVSAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKMDNKAANRTVIEKGRAGDLS"
     gene            complement(7505..8455)
                     /gene="pfkB"
                     /locus_tag="L1U99_002511"
     CDS             complement(7505..8455)
                     /gene="pfkB"
                     /locus_tag="L1U99_002511"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBN1213032.1"
                     /translation="MSIYTCTMNLAIDLFIETEEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPKIPQTAVHNFLNQIRALQAEDYLCVSGSLPRGLSPKVLIEISRICQEKGI
                     HLIIDSSDQEAMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVELGAENV
                     LLSLGEKGAILFTKDRVFRGNSPKGKVVNTACAGDTMLGAFLAGYMNRRPLDETLRKS
                     IAAGSSTAFRKGLTDFLDVEELSKQIKIKEERFETWENIN"
     gene            8598..9347
                     /locus_tag="L1U99_002512"
     CDS             8598..9347
                     /locus_tag="L1U99_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBN1213033.1"
                     /translation="MDHKLSETEQYLWNFIEHHILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINMLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISRKLT
                     KKDSVIFVSLNGETKELVTAAKNCYDAEIGSILVTANHSSTLKDYCEINLVGFKSEGS
                     YFPDYEVRSRLPLQIIARILLDAYVLRMGEN"
BASE COUNT         2808 a         2000 c         1640 g         3000 t
ORIGIN      
        1 aaagaaaggg gctatcccca gactttagta ggcgtcatta gctatctttc gttagcattt
       61 aaaggcgaac accatcacct attcacttcc attaaaagat agcatatttt tctgtaaaaa
      121 acaataaaat tatcgttctt tctttacacg ttcagcaaat tcatagaaag gagccaattt
      181 cgttaactgt tgattacatt ggtcactatc atgacaaata taattcccct ttttcgtata
      241 cgtgccatca gaacctgctt tcgttgtaga aagaaaaagc gacacattcg atgttttctg
      301 acagattgca cagattccct tatttatcgt tggtgataaa gtaccgctaa tcccttttaa
      361 tttttcatct tcgtaataga ccatgaattt tttctgcgta cctggatcat tccagccgat
      421 gtacgtatgt tcttgcaagt cgatttcatt ccaagctggt tgtttgagtt ttttcacttt
      481 tcggaataat ttctcgattt gtggtttgct aggctgcata aacggctgga cgatttgctt
      541 cagctcctcc aatgctcttt ctgcttgcgc ttttgtcagt tttacgtcta aaactgtcgt
      601 taaaaatgta tcgatttctg gcagttcgtg ttctaatatg tctcgaatct tttcagctgc
      661 tagtgcctga actgtttgta ccgtttttgg atcattgaca gatgagtacg catttaataa
      721 ctgatctact tctcttttta taaaaaaata ttggtatggt tttattgttt gttccatgat
      781 tttaaagtcc tttcttctaa ccaaagtgca tactttgtag aaaaaagtga tcttctgcaa
      841 agtatgtgtt acctgaagat cccggactct tttaaataag atacgttttg catcttatca
      901 tcaccccctt taatgttcat tcttctatgt acatgattca ttcgataaat aaaagtaaac
      961 cgtatcttga acagatagtc aactgcaaac agaaaaaacc gagaaaatca gccagatttt
     1021 ctcggaatat agtctattat tattggtttt acctattaaa tcgaggattc tttcccaaag
     1081 taacgttgcc atctcttacg catacttgca gacatgggct gagccgcttc tttgactgcg
     1141 cagtatttgt ccacgaatgt cacaatatat ccttctttat acttaggcgg tgcgatcgtt
     1201 gcaccccaca tgtgcttcaa aatgatatct cgctcaagat ccgacaaatc ggtgattttt
     1261 tctgcattct ttacagcaat tcttggatgg atatacgcat gtgtcccctc gtcaaatttc
     1321 gtcgtacgcc aatcatagta gaacagatca tgcaaaagtc cagcacgcgc tgttgcttta
     1381 gcattgccac cccatttttt tgcgagcaga taactatagt aagaaacact gatggaatgc
     1441 tccaaacgag tggaatgaac atgctgtgtg taattcgcta attttttcac tgcttctgtt
     1501 tctaaaagat cttgtacata agacatatat tcttcgtctt cacgccattt ttctgtcata
     1561 attatcgatc tgccaccttt ttgaatttca ttttcttctg aaattgatct aagtatacca
     1621 ccagtgttcg gattattcta gtcgctctag ataaaatagc taaagcttaa tagttcctta
     1681 atcataaaga aaaatgataa agaacgatcc ctgctgcgac tccgacattc aatgattccg
     1741 catttccttt cattgggata tatacgttct gatcagtcaa agacaagatt tcctgactta
     1801 ctccctgacc ttcgtttccc atgattatag cgaaatcctc tgttttttct actttgtcta
     1861 atgcatgtgc ttcttcattt aattctgtac cgtacaccgt aaaccctttg cctttcatta
     1921 cagggattac atctgccaaa tctttttgta acacaggcaa atgataattg cttccctgca
     1981 tgcttcgcag cacctttgta ctataaatat ctgccgttcc tttacctaat aaaacaccag
     2041 ccataccaaa cgcatctgcc gtacggatca tcgttcccac atttccagga tcctgtacat
     2101 tatctagtaa aagccagcct cctgaaaaat ctggcgtatc ttcagatgtt aacgtcatca
     2161 ctgctaagat cccttgcggt gtaggtagat ctgacatagc ggtcatgacc tcatctgaaa
     2221 ctagaaaagt agaaatctct ttgtttacag ccagccagtc tccccattct ttcatacctc
     2281 tctgtgtcac aaaaagttct tttatttctg cattagacga cgcagcttct tcgatcagat
     2341 ggaacccttc caaaagatat tctgcctttt cttctctgta tttcttttta tgtagttttt
     2401 ttaattcttt gattcttgga ttttttgctg attggatctc tttcacattc ctcacctcaa
     2461 ctgattatat catggaatag gtgcttgagc ttgtttcatc ctaaaaaaat cggtatcatt
     2521 gatttataaa acaggaaaga aaggtgacga acatgcgcaa agttaaaatg aatgtccaag
     2581 gacgtgtcca gggcgtggga tttcgctata tgaccaagat ggttgctgat cagttaggcg
     2641 tgaccggaac ggtaaaaaac gaagacgacg gctcagtcac aatcgaagca atcggaaatg
     2701 acgacatcat ccaaaaattt atcgaagaag tcaagaagtc tccgagccca agtggacgag
     2761 tgcagtatgt ggatgtccaa gaagatccga tgattgagga acgaaagaaa tttgatgtag
     2821 tgggataagg ttgtgaaaag gtcgcttagt tttgagtatt aaggaaaatt ttgtgaaaat
     2881 ggctttccac atttttgcat aaatttgact taataccgag aaactgactt ttgaacaccg
     2941 tcgataaggt tgtttttgaa gcgctttgcc tcgagtatta aggagaaaca ttttcaaaat
     3001 agcttctcat attttgaaat gtaatgactt aataccgaga ggcagctgat aaaacaccgt
     3061 caataaggtt gtgaaaaagc tggtctgcat caagcattaa ggactggttg tgataaatag
     3121 ctctccatat ttttcaacag gctggactta atgccgtaga tgcaagcttt tgaacaccgt
     3181 cgataaggtt gtttttgagg cgctttgcct caagtattaa agacaggtag taaaaaagct
     3241 gatctataac ttgcaatgaa tttgcttaac ccatattttc cagacagaac aaaaaagttt
     3301 ttagtttttt aaataagaaa gaaacacttg gaatcactct tttctttcta agtatttctt
     3361 tcttgatttt ttgtcttttt tcaaaatttt tcgctacgaa aaagaacgaa tatttatatg
     3421 aaatttctat gaagttgatt gaattccatg cgctttttta gtatagttaa gtttgtgtaa
     3481 aaattataga agaggaagta ttctatgaat aaatggaaaa actggttatt gggatccgga
     3541 cttgtcagta tcctgctctt tttatctggc tgtgtgcgga tggattcaaa cggaaaccct
     3601 gacacttcag gaatcgttta tcgagtactc gtccatccta tgggccaagc gattacatat
     3661 ctagttgaga atttcaattg gtcttacggc tgggcagtta ttgcaatgac tgtgatcgtt
     3721 cgtatcatca tcttgccact aggtatcagt caatcgaaaa aaacaatgat ccaatctgaa
     3781 aaaatgcaag cgttaaaacc acaagttgaa gcagcacagc aaaagctaaa agctgcaaca
     3841 acacgtgaag aacaaatggc agcacaagca gaaatgcagc aagtatatcg cgaaaatgga
     3901 ttgagtatga ccggcggaat cggctgtctg cctctattga tccaaatgcc gatcttctct
     3961 gccttgtatt ttacggcacg ctacacagaa ggtatccggg aatcatcttt ttacggcatc
     4021 gatctaggct caccaagtat ggtgcttgtg gccatcgcag gggtcgctta tctgcttcaa
     4081 ggatatattt caacaatcgg tattcctgaa gaacagaaaa agacgatgcg tacgatgctg
     4141 atcgtctctc ctgctatgat cgtcttcatg tcaatcagtg cgccagccgg tgttacactt
     4201 tactgggtag tcggtggtgt gttcagctgt ctgcaaacat tcatcacaaa cgttatgatg
     4261 aaaccacgtt tgaaagcaca agtggcagaa gagttgaaac aaaacccgcc aaaacaagtc
     4321 gtcactccaa gaaaagacgt gacagaatca gcaaagccag ctaacaacaa acaagcaaca
     4381 aaacaaatca aacaaccaaa aaacagtaca aacaacaaag gccgcaacgc aggaaagcag
     4441 cagaagcgga agtagatagt aaataagagt gtaataaaaa ttcattaaca gttttagcaa
     4501 ttaaaaatat cgaccaagat ttttgaaaaa gaaatctggt cgatattttt atttaagtga
     4561 atgtttaatt tgaatcatcg attgatcgct atctaattgc agcagcatct ttttatgaag
     4621 aaacaacttt ttcttatcta tcaacgtaga caggtgttgc tgtttcttct aatagtgtac
     4681 ttaattcttt aatattttgt tttccttctt ctaacatcca actactcgct ttttcttcgc
     4741 cttcggtaac aaaaggtgcc actcccttcg cccatgttgc tcgcccacat aagacaccat
     4801 tgaatgtcga acctgattgt tttgcaaaac gtaatgtatc ttgaaatagc gtagcattga
     4861 ctcccgcact taaaaaaata aacggttgtt cagtcacttt cgattgttca tagaaatacg
     4921 cggatgcctc tgcttgacta taacaagtct cttgcccata tccttccaca aatctcatat
     4981 tcactggcac ttctactttc aatacatcca cttgataacg ttcttttgaa aattctcgca
     5041 tggcttcaat aactttatgt ggttttactt ttgcataggc aagagaagac ggatcgccaa
     5101 tagttgcatc ataagaaaga atctctaaaa agaaaggtat gccttctgct tcgcattctg
     5161 aaccaatccg ttctataact atttgttttt gcacattaat ctctgctggt tcatcaacgt
     5221 catagtacaa taaaaattta caagcatccg caccagcttc ttttaacctt ttcaccgacc
     5281 aaatattcaa taaatcaggt aatcttcccg gtattttcgt atcatagccg gttttttcat
     5341 aagctagcag taagccacat tctttctctc gaagcgctgc tgcaggcagg ccgtattctg
     5401 gatcaagtaa aatagctgag gcatagggag tcaggtattg agaaaccatc tgtttaaatt
     5461 ggatgatgtc ttctgatgta gcttctttat attggttgat cattttcttc aaagcaccac
     5521 gctggtcgat tgctaatgcg ctaataattc cagcttcatc cgtcaatcgc ttcaaacgtt
     5581 cctgtttttc tatactcatc ttcttcatag atcttcacct atttctttag ttaatattgt
     5641 ggctatttct gtttttgatt ttgcttttct caactgttct gtaacctctt ttcgcatcaa
     5701 tgatcgtgca acgagagaca ataatttcaa atgagtcgtt cctgcttctg aatctggaat
     5761 aaataacgca aaaataaaat caactgactg tctatctaaa ctgttccatt caattccttt
     5821 gttcagtgtg gcgataatca tactaggttc gttgattgtt tgagacttcg catgagggat
     5881 agcaaaacct gacattattc ctgtagtccc ttctttttct ctttctagaa gtttttgata
     5941 tacttctttt tcgtcaagag cgatccctaa acagaatgtt tgctttgcta aaaacttaaa
     6001 tgcttcttct tgactatcca atggctgttg taaaaaaatg ttctcttcat gaatgattgt
     6061 catgataagt ctcctgctct tcctttttcg ataactgtac gatttgctgc tttattatcc
     6121 atcttcttgt ctttatcagt tactcttttc ttttggatta atcctagtat cactccacca
     6181 acgatcgaac caataagaat cgctgtaacc cattggattt ttcccgtcac tacaggtaac
     6241 actaaaaaac caccatgtgg tgctggaact tggacgccaa acaaataagt taagacagca
     6301 gcaattgatg agcctaacat catcgtgggt aacactcgga tcgggtcttt cgcagcaaac
     6361 ggaatagctc cttccgtaat atgagttgat cctaaaataa aattaaccaa acctgcatta
     6421 cgatcattgg tatcaaaata tttaccaaac aataaagtag caaaaccagt aatcaacggt
     6481 ggtgcaatac aagctgctga cacaccagcc ataaaagtcg tgtttccttg tgccaaaaga
     6541 gctgttcctg ttacatatgc cgccttatta accggtcctc ccatatcaaa cgcacacata
     6601 cagccaacaa tcacgccaag aacaagtgga ttcgaatgtt caaatccagc taaaaagctc
     6661 atcattcctt catttatagc cttcattgga cctgccagca aagacatcac gatgccaata
     6721 aatgctacac caataactgg atataagaag attgccttca agccatctag ttgtttaggt
     6781 aaaattgtca gtagcttttg caaaaataag ataaaataac ctgctaagaa cccagctaaa
     6841 atacctccta aaaatccagt accgccattc atggctacga ttccaccaac aaatccaacg
     6901 actaaccctg gacgtttcgc gatcccttct gcaatataag ctgctaaaac tggaaccatc
     6961 attcccattg ctgcatcgcc aactgctttt accattgccg ctgtagcatt gtattgtgca
     7021 tgatctggat caaaagaata gattccccaa acggcaaatg aaatagcaat caatactccg
     7081 ccagctacca cgaaaggcaa catatgagag acaccgttca ttaaattttt atagatgcta
     7141 cgaccaaaat tagcaccact catcgcttct ggttctaaag tatcagcagc ttcattatct
     7201 gctaagacag taccttttcc tgccaatgct tcgtcaatca gccgttgtgc atccttgatt
     7261 cctgtactga cagaaacatc aatgactcgt tttcccgcaa atctttctga atggacatct
     7321 ttatctgcgg caataatgac agcatctgcc tgtttgattt cttcagccgt taattcattt
     7381 tcgatcccaa tttgtccatg ggtctccact ttgatcttga tgcctttttt cctagctgct
     7441 tgttctaatg cctcttgcgc catgtaagta tgcgcaattc ctgtcggaca accggttgct
     7501 gcaattagtt gatattttcc catgtttcaa acctctcttc cttgattttg atttgtttac
     7561 ttaattcctc cacatccaaa aaatcagtca gtcctttacg aaaagcggtt gagctgcctg
     7621 ctgctatgct tttacgtaac gtttcatcaa gcggtcgtcg attcatatat cctgctaaaa
     7681 aagcgcctaa catggtatca cctgcacatg ctgtattgac aacttttcct tttggcgagt
     7741 ttcctcgaaa caccctgtct ttcgtaaaaa gaatcgctcc tttctcaccg agggataaca
     7801 aaacattttc tgcacctaac tctactagtc gttgtccata aacaaagtaa tcttcatctg
     7861 taaccatttt tcgtccgaac caagaagaaa gttcttcctc gttcggtttc agcaaaaacg
     7921 gtcgataggg taaacaatcc atggcttctt gatcactact atcaataatc aaatgaatcc
     7981 ccttttcctg acaaatccga ctgatttcta ttaaaacctt tggagacagc cctcttggta
     8041 aactcccaga aacacaaaga taatcttctg cttgtaatgc tcttatttga tttaaaaaat
     8101 tatggacagc tgtctgcggt attttaggtc cttgattcac taatttgtat tcttctcccg
     8161 tttgattgac ttgtgtaaat acattgatac gcgtcatacc aggcacttca ataaactctg
     8221 tttggatttg tttctgctgt aaatagtctt ctatatactt tcctgtaaac ccagcagaaa
     8281 aacctaatgc cgtacttggg aaatctagca tttttaatac tagtgacaca ttcacccctt
     8341 ttccgtttgc ctgaatgtca tcctcttttg tgcggtttac cataaaagga tgcatctcct
     8401 ctgtttcaat aaatagatca attgccaaat tcatcgtgca tgtgtagata gacataacca
     8461 acgacctcct tgactctatt atgaaatacg cgaaagagaa aatgttttct taatcgtccc
     8521 aacacaaaga aaacctttac atttataaac tcgtcgtgct attttttaac taacttttgg
     8581 tgaaagaagg aaagaatatg gatcacaaat taagtgaaac agaacagtac ctctggaact
     8641 ttatcgaaca ccacatccta gagatcccta actactccat cgtgaaacta agtgaacaag
     8701 caaatgtctc aacagccacc attgtgcgga caatgaaaaa gaaaggctat gaaggattta
     8761 cttcgtttaa gcaccatcta aaagaaggag aaaacaagaa catcaatttt tctttcttag
     8821 ataaagtaga caaaggtatc cgtcgagcca ttctaaaaaa tgaacaagaa gtggtacgta
     8881 cgatcaatat gttggaaatc ggaaatattg aggatgcaat acaaagaatc aaatttgctg
     8941 accgggtttt tgtctttgca cgaggatttt cagaaatgat tggtcaagag atgctcgtaa
     9001 aacttcaatt aacagggaaa aattgtcaaa tgcatactga tccagaaatc atcaaaagca
     9061 tcagtcggaa actaactaag aaagacagcg ttatttttgt ttctttgaac ggcgagacaa
     9121 aagaactcgt caccgccgca aagaattgct atgatgcaga gattggttcg attctagtta
     9181 cagccaatca ttcctctaca ctgaaagact attgcgagat caatctcgta ggtttcaaat
     9241 cagaaggttc ttatttccct gattatgaag tacggtcacg tttgcctctc cagattatag
     9301 cgagaatcct gcttgacgcc tatgtattgc gtatggggga gaattgaaaa gcagtttatt
     9361 atggttggtt acagtttaaa acatcacatt ttttattctt tatattgtat ggactcacgg
     9421 aaacttttta tgtataaagt tattcaca
//
LOCUS       DAFLVO010000092         9131 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.094, whole genome shotgun sequence.
ACCESSION   DAFLVO010000092 DAFLVO010000000
VERSION     DAFLVO010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9131
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.094"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            166..239
                     /locus_tag="L1U99_002513"
     tRNA            166..239
                     /locus_tag="L1U99_002513"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:200..202,aa:Ile,seq:cat)
     gene            complement(624..1121)
                     /locus_tag="L1U99_002514"
     CDS             complement(624..1121)
                     /locus_tag="L1U99_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBN1213034.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(1161..1970)
                     /locus_tag="L1U99_002515"
     CDS             complement(1161..1970)
                     /locus_tag="L1U99_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1213035.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            2304..3161
                     /locus_tag="L1U99_002516"
     CDS             2304..3161
                     /locus_tag="L1U99_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBN1213036.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            3154..4056
                     /locus_tag="L1U99_002517"
     CDS             3154..4056
                     /locus_tag="L1U99_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBN1213037.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            4089..4439
                     /locus_tag="L1U99_002518"
     CDS             4089..4439
                     /locus_tag="L1U99_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBN1213038.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            4488..5411
                     /locus_tag="L1U99_002519"
     CDS             4488..5411
                     /locus_tag="L1U99_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBN1213039.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            5489..6382
                     /locus_tag="L1U99_002520"
     CDS             5489..6382
                     /locus_tag="L1U99_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1213040.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            6420..6983
                     /gene="amaP"
                     /locus_tag="L1U99_002521"
     CDS             6420..6983
                     /gene="amaP"
                     /locus_tag="L1U99_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBN1213041.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            6997..7185
                     /locus_tag="L1U99_002522"
     CDS             6997..7185
                     /locus_tag="L1U99_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBN1213042.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            7198..8100
                     /locus_tag="L1U99_002523"
     CDS             7198..8100
                     /locus_tag="L1U99_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBN1213043.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            8132..8374
                     /locus_tag="L1U99_002524"
     CDS             8132..8374
                     /locus_tag="L1U99_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBN1213044.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(8630..9001)
                     /locus_tag="L1U99_002525"
     CDS             complement(8630..9001)
                     /locus_tag="L1U99_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213045.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         3193 a         1566 c         1759 g         2613 t
ORIGIN      
        1 cattttttct aaaataagca aataaaaatt aaagtaacaa aatagttatg acacaagtaa
       61 aagaaataag aataacaata ttattttact tatattttga aacttgtgag agtttgtcat
      121 tcgtgctata gttgaaaagt aacaaaaata aattttattt atgatgtacc tttagctcag
      181 ttggttagag cagacggctc ataaccgtcc ggtcgtaggt tcgagtccta caaggtacat
      241 aagaggttgt gaaaaagctg ccctgcatca agtaataaga acagccaagt aaaaacagct
      301 tcttatgttt ttacttggct gttcttatta ctgcagatgc aagcttttga ataccgttta
      361 aggaagaggt tgtgaaatca gcgttttgac ctgagtatta gcttaacaaa cggaaaaata
      421 gttcctcata ttttgccgtt tgttaagcta ataccgaggg tcagctgatt gaacaccatt
      481 taagaaagag gtcgtgagcc tgccgtttca ctctgtgtca taaaaaagcc aatctacttt
      541 gatagaaaaa gcacgtagga ctaaaacagt tctgcgtgct ttttttattg tgtgttaaat
      601 atcgtaaatg aagatagata tttttatgat tcgacgatag agacgttgaa atctttcaac
      661 agctctaaag cggattctcc gtgttttcta ctggagacta acattggatc aacaaaaaag
      721 tctgcttcag gaaaagcact ctgcaggcct atcagattag agagtacaca caagtttgtt
      781 tcaatcccga ctacttcgat ctctttttgt tcttctttgc tttcaaataa agtttcctgg
      841 atttcagcta aagtttcagg tggaatcgta aagtaatact ttttaatcac tcgttcattt
      901 tcttgtggag aaagaagagg gatcaattgc aaatcttctc gttcttcttc tttgtccttc
      961 agttcaactg gtatatcccg tgtgaagaga atatattcat tattttggcg tgctttagct
     1021 aatctttgag caatacgttc tgccaattga tctgactctg gaatataaaa ttcgctgttt
     1081 ggatcaagaa tatgattttg catatcaata ataactaaca ttttctttcc tcctacattc
     1141 atatcgtcat tttattcttt ttaatagaag ttttttaaaa tataagcaac accagcttct
     1201 tcattcgtca gtgttacttg gtttgcaatt tcttttactt gtcgctgtgc attccccatc
     1261 gcaatactca acccgctgta attcaacata gcaatgtcgt tttcttgatc gccaaaagcc
     1321 atgatgtcac tcgattcgat tccaaggtaa tccgccagaa aaacaagtga atgagcttta
     1381 gtgatacctg taggcgtgat ttctaagaaa tgcggatcag agaatactga ttggatacca
     1441 tctgcttgca gatctctttg tagcttctgt agtttttctt cactcttatc tgttaatgct
     1501 aatttaagat agctaagaga aggatcttcc aacatattta aaatttgatc aaaagaatgg
     1561 ttctgtaaat tgaaatgttc ataataaggg tcatctttga ctagatttga ttcatcgaat
     1621 gtcagctgat catcttgggt ttctcggcta gcaatgatgg atattttcgc ttcttgagca
     1681 tagaagaagg cttttctcag tgtatcgcta tctatttttg aacgtctgag aactttcgcc
     1741 atttttccat ccttcatttc agcaatcagt gaaccattgg aagaaatcaa atagccaccg
     1801 attcctaatt cggaaaaaat atctttagca gaaatgctgt tccttccggt agcgacggtt
     1861 acgattccgc cattttcatc aaatttccga agtgcttgga tattttcttc tggtatcttt
     1921 ccatttcgat caagcaaggt accgtctaaa tcaatcgctg ctagtttcat tttatcttcc
     1981 tactttcttt ttacatatct attttcctgt taccttaaga ttaaatgaga atttaaaaaa
     2041 atgaaactaa cttgctttgt cattatgaat tttttcaaaa aacattctta agaaaaaggt
     2101 ggctatatat agtagttttt ggtcaatacc tttgaataaa aagccatgaa aaacgaatag
     2161 ttagcgctta ccgatgcgtt ttgtgataaa aaaattttaa aatattcaat gaaaacaaag
     2221 catatatttt gctttaaaac caaatgagga atattctaga tgtagaacag gttagaaaaa
     2281 gattagaaaa aggagtgatt ttgatggaga agagatacgg cgtagttcct gtggtaactg
     2341 cttcagacga aaattatgct ccttacttga gcgtgatgat cgcaactgca ttagaaaatt
     2401 gcaataaaac aagacgcata aaattttatg tgattgacga tggtctatca gaatatagta
     2461 aagaaggatt ggaagaaacg gtaaataaat attcaagtaa tgcaagtatc caattcctga
     2521 cagtggaaaa agatatctac gaagacttcc tagtcagtga ccatatcaca actaccgctt
     2581 acttaagaat ttctttacca aacttattag ctaaagagga ttataagaaa gtcctttact
     2641 tagattcaga tgtgttagta ctagacgata tcgtaaaact atatgatgag ccgttaaatg
     2701 gaaaaacaat cggcgctatt atcgatccag gccaagtgaa agctttggaa agattaggaa
     2761 tcgattccga tgacttgtac ttcaattcag gagtgatggt gattgacatt gatcaatgga
     2821 ataaaaaaga aattacagaa aaaactatcc attacctcag tgaaaatggc gatcgaatca
     2881 tctatcacga ccaagatgct ttgaatgctg tactttatga agattgggaa caacttcatc
     2941 caaaatggaa catgcagact tcgctgattt ttgaacgtca tccagcacca aatgaaaaat
     3001 atgaacgtca gtataaagaa ggaaatgaaa aaccttcgat cgttcacttt acaggacatg
     3061 ataaaccttg gaatacgttg aaagatcatc cgtataccaa tttatactta aaaaaattag
     3121 cacacagtac tctaacgaaa gtaggcgaga tcaatgaata aaaaagaaat agcagtagtc
     3181 gcaagttgta acacaaaatt cgtaccacat ttagctgcat tatttgtctc agtattagat
     3241 aattgcaacc cgtctaaatt tgttcggttc tatgtgattg acgatgatat cgattttgaa
     3301 agtaaacagc ttttacgctt ctcagtgaaa aacgcacgaa tgaactcaga tgtggaattc
     3361 ttgaaaatca ataaagaatt ctttacaaat gtggtaatca gcgatcgtat tccagaaaca
     3421 gcttattatc gtattgcgat tccggaattg ttccgcggca cagaagttga acgtatctta
     3481 tatatggatt gcgacatgat cgctttacaa gatatctcta aattatggcg tcttgacttc
     3541 ggtgattcaa tcgtagcagc tgttgaagac gctgggttcc atcaacgact ggaaaaaatg
     3601 aaaatttcag ctaaatcaat gcgttatttc aactcaggtt tgatgctgat caatgtgaaa
     3661 aaatggttag atgaaaatat tacgcaaaaa gtattagatt tcatcgaaca taatccagaa
     3721 aaattacgat tccatgacca agatgcatta aatgctatct tacatgaccg ttggttacca
     3781 cttcatccgc gttggaatgc acaaggctat atcatggcaa aagcaaaaaa acatccaaca
     3841 gcagcaggtg aacgtgaata cgaagaaact cgcaacaatc cttacattat ccatttttca
     3901 ggacatgtga aaccgtggag caaggatttt gaagggccaa cgaagaaata ttacgaaaaa
     3961 tatgcaggga tgacggcttt ccgttgtgta gctaaattcc ctaaatatcc aaaatatgca
     4021 aaagttcaac caaaaacaga tgtagttgtt aaataataga agaccacaac tgaagagggg
     4081 gagtaggaat ggaaattaca atgtctaaaa atgcagtaga gacgttaatt gaaaaggttg
     4141 gggaaaatac aaaaatcgca ctcgcgctta tcaatgattc cgatccattt ctaagggaca
     4201 aaggtgcttt tgcaaaaggc agcttttttc aaatcattcc ttttgtttcg gaatttggag
     4261 aatatgcgac taaaatcgag catccattat tggacatcta tacatctaaa ttagagcaaa
     4321 attatttcgg taaacgattg aacatggact tcaacaaaca gcttgacagc ttttcattag
     4381 aaaatgaaat cgcagtactc gattataata tcaaattaaa gaactgcttc ttcagctaat
     4441 agtttcgaga aagtccaaaa aggaggtata cattgagata ctactttgtg gatgaagaaa
     4501 agaatgtaat agaaacagat gaaaaaaaat ataattggct cgtacttgat agtgcaaagc
     4561 ccgaagagat tgagcaagca atcgaagaat tcgagcttcc tgatgatatt ttcgtaggaa
     4621 ccgaatatcc ggaagaagtt tctcggatgg agcgccttta tgagacgaaa ctagagcatc
     4681 cattttcttt ggtagtgatt aatctagatc agtcagataa tcgtatcgaa aaaaaattaa
     4741 cgccaatatc ttttgtactt tccgataatc tcttgattac ttgtatcgat agaaaaaccg
     4801 aatttgtgga tcggctgctg acaaagcatg gaaatcattt aaactcgttt gaaaagatca
     4861 tcacgtatac attattagat atttacaccc attacgtgaa agaactaaga gagatgaaaa
     4921 agcgaattga cgctttggat aaagcagctc gtaaaacaac ggaaaatgaa gaactgtata
     4981 aacaggcaga tcttgaaaga gacatcgtat atatcgatca taccttaaga gatcaacggg
     5041 aaacaatgga tcaattatgg aattctgaaa ctttcatcaa acgtttagac gatgaacagc
     5101 tactctatga tgtccatttg agacagcgac aaacagaaaa aatgatcgag atctatcgag
     5161 atttattaga gagtattggt gatctattca acgggatgat ggacaataat ctaaatcata
     5221 tcatgaaata tctagattca gctgcattaa tcatttccgt tccggcgttg ttcgcaggga
     5281 tttggggaat gaatacagga ggattaccgg gtaaaagttc tgctctaggc tttatactcg
     5341 tagtctttgg ctctttgata gcagcagtag ttttaggtta ccatttatac cggaaagatt
     5401 atacaaatta aagaatctat ttaaaacagg tatcaaacaa agaaatttgt tttggcaata
     5461 caatttaaaa actaggagga atacagcaat gacagaacca aaattaatcg acccgcgaaa
     5521 cttgtaccat acggagaaat ttcctaaaca agatcaggat acaccagctt tacagcagaa
     5581 tatgattcct gttcctgatt gtggagaaga atcctatgaa ggcaataatc aactagaaaa
     5641 ccgccgtgta ctaatcactg gtggagattc agggatcggt cgtgcagcag cgattgcatt
     5701 tgctagagaa ggggcagata tcgctcttca attcttccca ggagaagaaa aagatgcaga
     5761 ggaagtagca aaatacgtga aagatgcagg acgtaagatt gtcttactac cttttgatct
     5821 tcgtgacgaa caagcaccta aagaaatcat agataaagcc gtgagtgaac ttggcgggct
     5881 agatacgatg gtactaaacg caggacagca aatttcttgt cagtctattg ctgagttacc
     5941 acttgagcaa gtcaaagaca catttatgat aaacatcatc gctatgtttg ctttagtgaa
     6001 agaagctgtt ccgcatatcc cagcaggagg agcaatcgta acaacaactt ctgttcaagc
     6061 attcaatcca agcgaacatt tattagatta cgcagcaaca aaagcttcaa tcgctaactt
     6121 tacgatcggt ttagcaaaac agcttgcacc taaaggaatc cgtgtaaatg gtgtagcacc
     6181 tggtccaatt tggacaccat tacaactaga cgaaggacaa ccttctgatt cgatccctga
     6241 atttggtcag caaagtttac tagaacgtgc aggtcagcca ggagaattag caccagttta
     6301 tgttttctta gcatcgaata aagcaagtta tgttacagcc caaatttacg gagtaactgg
     6361 tggagaagcg atcaacttat aagaagttga tcgtttcacc cctatgagga ggtgcgaaaa
     6421 tgaataaagg tgtaaaaacg atcggagtga tcggaacatt acttttgcta tctgtgcttt
     6481 tgtttgcgat actattaagt gcaacctatc cattgccttt tcagctagag aagtttcgat
     6541 tcttttccat cactaattca tacgtgcaac aatatgtatt ttggcttgcc gttgcatttg
     6601 ctattttgac aattatcacg ttacttgttt tcctgtttta tccaaaaaca atcggaaact
     6661 ttctactgaa acatggtgat ggggagttga cgttggataa aaaagcaatt gaaggaatgg
     6721 ttcgttctca cttgcatgaa gatgaattca tccattcacc aaaagtaaat gtcaaagcaa
     6781 cgaaaaacaa gatcgccgtc aatgtaaaag gggagttgaa acgaacttca gcactcattg
     6841 gtaaaacagg aacattgatg aaagaaatcg aaaatgaagt acaacacata ttgggaacaa
     6901 aagagccagt gaaagtatcg gtgaaataca caggctttga agaaccagct aaacgaagca
     6961 atgaccgcaa acgagtagaa taggggggga ccaaaaatga aagaactatt ttcgacatac
     7021 aagctcccta tcatctttgg ggtacttgga ttgatattag ccgttttatg gatcaccgtg
     7081 ggctttttca agaccttatt gatcttgatc atggcagcga tcggcgtcgc tatcggtttt
     7141 tatctgaaac aaacgaaaat cttagatcac tattttaaat cttaggagga aacatccatg
     7201 aataacaata acaaaaataa taacaataaa atgaacaacc aaaaaccagt gtctgcacat
     7261 ccagacccaa cgacaccaaa ccaatcaaat ggtgtgaacg atgaaaagaa caaaacagca
     7321 ccagtatctg cacatccaga tccagtagtc cctaacgttc aacaaggagt agaagagaag
     7381 aaacatgatg cagaaaagca tgcacctcat catccaggaa ctccagaatc taaagttcca
     7441 gaacaacatg atgcaatcga tccttctaaa cctgtggaag agcaaaaaca tccttctgac
     7501 catgcgaaag cacaagaaaa acttagttct gaccacacaa acggacaagg aaaacttggt
     7561 tctgatcata caaataacca aggaaagcat gattctgaac aggaagattc aatgcgcggt
     7621 gagctgaatt atgaagataa agttgtgcaa aaaatcatcg gaatcgcaat tgaacaagta
     7681 gacggtttat tatctgcaaa cggtggtttc ttctctaatg tggcaggaaa acttgtgaat
     7741 acagataatg taacggctgg gatcgaaaca gaagtcggta aaaaacaagt agcagttgat
     7801 atggatgtca ttgtggaata tggcaaagat atcgaaaaaa tctttgaaga aatgcaagaa
     7861 gtaatcggca aagaagtaaa aaatatgaca catttagaag tgatcgaagt caacgctaac
     7921 gtagtggaca tcaaaacaaa agaagaattt gaaaaagatc aagaaacggt gcaagacaaa
     7981 gtaactgacg cagcgaaaaa aaccggtgaa tttgcttcga atcaaacaga taaagtaaaa
     8041 tcagcagctg gaagcggcgc acaaaaagta aaagaaaata cagaaccacg ggttcagtaa
     8101 taaggaagta aaacattagg aggaacgaaa catgggattt atttggtcac ttatcgtcgg
     8161 aggaattatc ggagcaattg caggagcaat cacgaataaa ggttcttcga tggggattat
     8221 tgcaaatgtc gtagcaggtt tagttggatc agcacttggt caagcattat taggttcttg
     8281 gggaccaagt attgcaggaa tggcaatcgt gccatcattg attggtgcca tcattttagt
     8341 actaatcgta tcattctttg ctcgaaaact gtaaaaagac ttttaaaaag aggtcgtgaa
     8401 aaagctgttc ttcatcaagt aataagaaca gccaaacaaa aatagcttct catatttttc
     8461 atttggttgg gcatattatc gaagatgcaa gcttttgaac actgtttata cggaataaga
     8521 ggctgtgaca agacttttgt cacagcctct tatttatgcg ggcaaattcc caattagatt
     8581 tttaaaagtt tttccttaaa tgtgtcttta ttgatacaga gaagcttctt taataaaaca
     8641 atgcctccct aaattttctt gagataggaa aggtgaacat acaaaataat acgaccactt
     8701 tgaaaaccca gatgatccac aaatggatcg tatgatactg atgaagtaaa aagcaatgga
     8761 tcagaaactc aaagagattg aaaaagacaa ggaagaaata atatctcttt tttactcttg
     8821 tctgttttag ccaataatag ctcgtaaagt aatctagaca aacaaataga agtaaacaaa
     8881 gtttcgtaag agcagcaatc gtatcatgtt gctctgctag acgattgacg agcaggaaaa
     8941 atgttggtaa tggaatatag atcacgagta atgaaagaaa aaagtaaaca ataaatggca
     9001 tactattcct cctaattgtg tgagttcgcc ctcattttaa aataacgata tttgtttgtg
     9061 aagctttttc gtgtcgtaac aaatgttatc taatgtattt ttaaataaat aatcattatt
     9121 atcaaaataa t
//
LOCUS       DAFLVO010000093         8983 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.095, whole genome shotgun sequence.
ACCESSION   DAFLVO010000093 DAFLVO010000000
VERSION     DAFLVO010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.095"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            2..74
                     /locus_tag="L1U99_002526"
     tRNA            2..74
                     /locus_tag="L1U99_002526"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="L1U99_002527"
     tRNA            78..150
                     /locus_tag="L1U99_002527"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="L1U99_002528"
     tRNA            155..225
                     /locus_tag="L1U99_002528"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="L1U99_002529"
     tRNA            238..311
                     /locus_tag="L1U99_002529"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="L1U99_002530"
     tRNA            323..394
                     /locus_tag="L1U99_002530"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     regulatory      583..662
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            660..1853
                     /locus_tag="L1U99_002531"
     CDS             660..1853
                     /locus_tag="L1U99_002531"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBN1213046.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1983..3455
                     /locus_tag="L1U99_002532"
     CDS             1983..3455
                     /locus_tag="L1U99_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1213047.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3538..4326
                     /locus_tag="L1U99_002533"
     CDS             3538..4326
                     /locus_tag="L1U99_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBN1213048.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(4393..5061)
                     /locus_tag="L1U99_002534"
     CDS             complement(4393..5061)
                     /locus_tag="L1U99_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HBN1213049.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5176..6888
                     /locus_tag="L1U99_002535"
     CDS             5176..6888
                     /locus_tag="L1U99_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1213050.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            6891..8663
                     /locus_tag="L1U99_002536"
     CDS             6891..8663
                     /locus_tag="L1U99_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1213051.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(8745..>8983)
                     /locus_tag="L1U99_002537"
     CDS             complement(8745..>8983)
                     /locus_tag="L1U99_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1213052.1"
                     /translation="AYNQSLRAVSKELNLDKKVSSHMLRHSHISLLTELGIPLKAIMD
                     RVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT         2693 a         1518 c         1987 g         2785 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaaa
      541 tgaaaaaata cgagcagaaa actgttttat ctgctatact tggttcgttg caagttcccg
      601 aaaggatccg caggacggag atgccttgta accgaattta actaggggga atcattataa
      661 tggtagaaag acacttattt acatcagaat ctgtttctga aggacatcca gataaaattg
      721 ctgaccaaat cagtgatgca atcttggatg caattttaaa acaagatcca acagcacgag
      781 tagcgtgtga aacgtctgta acaactggtc ttgttttagt atttggagaa atatctacga
      841 cggcatatgt agatattcaa aaagtcgtac gggaaacaat aaaagaaatt ggttatacac
      901 gtgcaaaatt cggatttgat ggagatacag cagctgtatt ggttgcgatt gatgaacaat
      961 ctcctgatat tgctcaagga gttgatgaag cacttgagat ccgggatgaa gataaaaaag
     1021 acgtattaga tgagattggt gctggtgacc aaggtttaat gtttgggttt gctgtagatg
     1081 aaacaccaga attgatgcct ttaccaatcg ctttgagtca tcgtctggta cgacgcttgg
     1141 cagatttgcg taaatcaaat gaattaacgt atttacgtcc agatgcaaaa tctcaagtaa
     1201 cggttgaata tgatgatcaa ggacaaccgg aacgcgtaga tacaatcgtt atttcaacac
     1261 agcatgatga tgcagtagat aatgaaacaa ttcgtcatga tgtcatcgaa aaagtagtga
     1321 aggaagttat tccagctgaa ttattagatg atcaaacgaa atattatatc aatccgactg
     1381 gccgatttgt cattggtggt cctcaagggg atgccggatt aacaggaaga aaaatcattg
     1441 ttgatacgta tggcggttat gctcgtcatg gtggcggtgc tttttctggt aaagatgcga
     1501 caaaagttga ccgttctgcc agctatgctg cacgttatat tgctaaaaac attgttgcag
     1561 cagggcttgc tcgcaaagca gaagtacagc tagcttatgc gattggtgtt gctcaacctg
     1621 tttcgatctc aatcaatact ttcggtactg gaacggttcc ggaagaagaa ctgattgctg
     1681 cagtgagaga aaacttcgat cttcggccag caggaatcat cgagatgctt gatttgcgtc
     1741 gtccgattta caaacaaaca gctgcttacg gtcattttgg tcgtacagat gtagatttgc
     1801 cttgggaaca tacggacaaa gtagatgcgt tgaaagcaag tttagcaaaa taagttatat
     1861 tcagctggaa cgatcgccaa gtggtggttg ttccagcttt ttttatggca gttaacctct
     1921 tgaaaaagat agtaattatt tatctatttt tagatcctgt cataatgaaa gggaggaata
     1981 agatgaaaaa agaaacaaat gttactttgg tcacagtgag tattttcatt gcaacgttca
     2041 tgacggctat tgaaggtaca atcgtaacaa ccgctatgcc aacgattgtc ggttcattac
     2101 atggaatgga aatcatgaac tgggtatttt cgatttattt gctgacaaac gctatgctta
     2161 ctccgattta cggaaaactt gcggataaag tgggacggaa accaatcttt atttttggga
     2221 cattattgtt tattatcggt tcgttatttt gcggtttatc tcaaagcatg attgggttga
     2281 ttgctgctcg tgcgattcaa gggatgggtg ctggggcaat gatgccagta gctttgacga
     2341 tcatcggcga tctttattct attgaaaagc gagcaaaagt tttaggtttg aatagttcag
     2401 cctgggggat tgccagtgtt tttggaccgc ttgcgggagg attcatcgtt gaaacgatca
     2461 gctggcactg gatctttttt atcaatgtgc cgatcggaat tctattaatt attttgattt
     2521 ggctatattt aaatgaacca aaaatcatac atgagtctaa accaatggat atttttggta
     2581 gttttagttt gatggccatg cttgtctcat tgctgttagg gttccaatta ttaggagacg
     2641 aaggaatgag tccgcttgtt tctgctttgc tgctaggtag tatcgtaatg ttaggtattt
     2701 ttgtttttgc cgaaaaaaga gctaaagatc ctgtcatcat gatgcattta ttcaaaaatc
     2761 cactatttgt tgtggtcaac ttggctgcag cattggctag tggttttttg atgggaatcg
     2821 atgtttatat ccctatgtgg atgcaaggtg tattagggct gaatgcagca attggtgggc
     2881 tggtattagc accattatca ctagtctgga tggtcggttc tttccttgca agcaagtgga
     2941 tgactcaaat gaaaactcat tgggtcttga gaattggact actaatcgca gctattgggg
     3001 gcgcttggtt gtatcttatg cctttcagaa gtaactattt atggtttttt gctatatcaa
     3061 cggtcatcgg tataggctta ggtgtgacca tgactacctc gactgtcagt gcacaaaata
     3121 gtgtatctcg tgaccagctt ggtgtagcaa cttcttttaa tacgttagtt cgaacaattg
     3181 gtcaaacagt catggtttct atttttggtt tattgataaa tggggtaact aaacgagaac
     3241 ttgcagcagc aaatttaaca aatgatgcag atatcatgaa taaactggtg aatccacaaa
     3301 cggctaaata tattgatgcg gatattttgt taccattaag aaaaattctt tatgatgggt
     3361 tacattccgt ttatctagtt ggcttgttac tcgtgatcat tgctttggtc ttaacgcttt
     3421 tcgttcatga aaaaagtggt aaaataaaac agtagtttcg gttaagatat gtacgtagcc
     3481 gaatcattca aatttaaagt tattcaaaaa taacttctta ctaaggaagg cgaaaatatg
     3541 gcatttattc aagcaaatat ttattcgaat gtgttagaaa tggaagtcaa tctaaatgtg
     3601 atactaccgc aaacaacaaa aaaggtgatt ggcaccagtt cagagcaaga gacaacggat
     3661 atacctgttt tatatttact tcatggaatg ggtggcaatc atagtgtatg ggaaagacgt
     3721 acgtcgattg aacgttatgt agcaaactac ggattagctg tcatcatgcc atctactgat
     3781 cttggctggt acacagatac agtttatgac atgaagtatt ggacattcat tgcagaagag
     3841 ctacctgaga tttgtcatga attattcccg caattaacaa gaaaaagaga aaaaacatat
     3901 gccgctggat tatcgatggg cggatatggc gcgttaaaac taggccttgc aaaatcagaa
     3961 aatttcgcag cagtaatctc tctttcaggc gctgtttctg taggaaatcg aatggatgat
     4021 cttttgatgg ttcgtaaagc atctttttgg gaagggatct ttggaccatt ggatcaaatc
     4081 gaaggttcaa aaaatgatcc gcaatactta ttgaaagaac tagtaaaaag cggaaaacca
     4141 gttccaagat tttatatggc ttgtggggaa tctgattttc tttatcaggc aaatcaggaa
     4201 atggtatctg ctatgcagga acaaggcttg gcggtcacct ttgaacaagg acctggcgat
     4261 cataactgga tcttctggga ccaatggatt caacgtgcat tggcgtggct aatggaagaa
     4321 aaataaaaaa agagtcttaa aaagatagct cctatagaga tcacaaacat agtgatctct
     4381 ataggagctt ttttactgct cgttttctct tcttttattt tgttggcata agccttcaat
     4441 ataggtttgt gcactcgtta gaaagagtgc tttttcattc aattctgcat gggactgcat
     4501 actttcttta aatccctcta attgattttc aactacataa ttacgcataa atagaactgt
     4561 ttctttcaaa aattcatttc cgtccataat tttttgtcga agctgctgtt catgctgctg
     4621 atccattaac tgtccaatca ataaattgtg gagagaggca atggcctgat gactttgggt
     4681 gactgaaaat ccttcacgaa caagtaattg gatcatttgc tccaaatgtt ctaatcgact
     4741 cggaaaagcg ggcacagtat tgatttctaa ttctgcccca caagggaaac gtgtataaag
     4801 gtcatagtaa ttttccatat actgcagcaa ctgttcattc caaggcaaag ttggatctgg
     4861 aagcgctaat tcttcttcca ttgtttcagc cattatttgc aagagctgtt gtttgttttt
     4921 gaaataccaa tataaagcag gtgcttgaac atgaattctg tttgcgatgt ttcgcatgga
     4981 aagctgcgaa agagcttgtg tttcagccag gatatcaaag gcggcctgaa tgatgattgc
     5041 ttgagaaagc tttatttcca ttttatcaac ctcgtgtatt gcattatctt tttaaacatg
     5101 gtaaattgtt agtcggtcta attttacagt gttaaattag tcctgtcaat ttaaacaaag
     5161 gggtgtaatc aacgaatgaa attaatctta cgacatgcga aaaaatataa agtagctgtt
     5221 tttatttcct tgctgtccgt agcagtcatg gttgcagcag cattatggca acctaagtta
     5281 ctacagcaag tattggaagc tattattaca gaagataatg atgaaatgaa aacaattggt
     5341 atttacctga tcagtctggc tttgctagga ttagccgcag gtgtaacgaa cacgattttc
     5401 tctgcaaaag tagctcaagg cgtaagtgca gatatccgag aagaagcatt tcgaaagatc
     5461 cagacatttt catttggaaa tatcgaacag ttctctgctg gaaatcttgt tgttcgtcta
     5521 acaaatgata tcacgcaaat ccaaaattta gtgatgattt ctttgcaatc actttttcga
     5581 attccattct tatttattgg tgccttcatt ttagctatga tcacgatgcc gcaattatgg
     5641 tggatcatcg tagcgcttat cgttacggta tttctgatta cggcactttc atttacaagg
     5701 atgggcaagc acttcatgat cattcaaaaa ctgattgatc gtgtgaatag cattgcaaaa
     5761 gaaaacttac tagggattcg tgtagtgaaa tcttttgtac aagaagaaaa ccaattgaag
     5821 tcattcagca aagtaagtga ggacttaaca aaacacaaca tcatagtcgg tacattattt
     5881 tctgtgatga tcccgtcctt catgctggct gccaatttgg ctgtggttgg ggcgatcttt
     5941 tttgtgagcg atcttgttaa agatgatcct acgttaattg gtggaattgc ttcattcatg
     6001 aactacttga tgcagattat gatggcaatc attattggcg gaatgatgat gatgatgact
     6061 tcaagagcag ccgtatcgct gaagcggatt gcggaaattt tagatgctga accagatctt
     6121 acttatttag acgttccaga acaagagttg acgggttctg tcacttttga ccatgtttct
     6181 tttcgttatc ctggtgagga tacagatacg cttaaagata tcagcttttc tatcaaacct
     6241 ggagaaatgg ttggtatcgt cggggcgact ggtgccggga agtcaacact agcacaattg
     6301 atccctcgtc tatttgatcc gacagaaggc aaagttgaag taggtggtgt agatcttcgt
     6361 caagtaaatg aaaagagttt aagacaaacg gtttcctttg ttttgcaaaa agcaatttta
     6421 ttctcaggaa cgattgctca aaacttgcgc caagggaaaa agaatgcaac agaaaaagag
     6481 atggaacatg cttcttctat tgctcaagca aaagaattca tcgaaaagtt atctgatcgt
     6541 tacgaagcac caatagaaga acgtagcagt aacttttctg gtggtcaaaa gcaacgttta
     6601 tccattactc gtggcgttat cggtaatcca aagatcttga tcctagatga cagtacgagt
     6661 gcactggatg ctcgctctga aaagctggtc cgagaagcac tcgatcgaga tttgaaggga
     6721 acaacgacga ttgtcatcgc acaaaaaatt gcttctgttg tcaaagcaga ccgcatctta
     6781 gtattggatg aaggcagatt agtcggcgaa ggaacccatg aggaattggt agctggaaac
     6841 cgtgtctatc aggaaatctt tgaaactcaa aaaggaacgg aggagtaagt atgactgatc
     6901 taataaaagc aagtaaattt ttctatcact atttgaagcg gtacaaactc tcctttttct
     6961 ttatctttat cacagtgatc attgctacct atctacaagt aaaggcacct caatacatcg
     7021 gggaagcttt tcaagaatta gctaattacg taggaggctt gatgcaaggc gtagacgata
     7081 aaagcaaatt tgtttctgta atatggaaac tcttgctgtt ttatgtacta gctagtgcag
     7141 ccaactttat ctatagtatt ttgttcacac aagtagtagg gaagtcaacg aaccgaatgc
     7201 gtatcggtct attcaacaaa ttggaaaaat tgacgatccg tttctttgat tctcatcaag
     7261 acggtgaaat tttaagtcgt tttaccagtg acttagataa tattcaaaat agtttgaacc
     7321 aagctttgct tcaagtcatc acgaatgctg ttttacttgt cgggatcttg atcatgatgt
     7381 tccgccaaaa tgtagagtta gcttgggcta caattgcttc cactccagta gccgttttga
     7441 tagctgtctt gattatccgc aaagcacgga aatatgtgga tcttcagcaa gatgaagtgg
     7501 ggaaactaaa tggttatatg gatgaaaaaa tcagcggaca acgtgtcatc atcacaaatg
     7561 gcttacaaga agaaacgatt gaaggattct tagagcataa tcaaagtgtt cgcgaagcaa
     7621 ccttcaaagg acaagcttat tctggtctac tatttccgat gatgcaagga atgtcactgg
     7681 tcaatacagc gatagttatc tttttcggcg gctggttagc attaaatggt gatttggaac
     7741 gttcggtggc attaggctta gttgtgacat tcgtccagta ttcacaacaa tattaccaac
     7801 cactgatgca gatttcatct ggatacagca tgatccaatt agcgattaca ggggcaagac
     7861 gattgaatga aatatttgat gaaaaagatg aagtcaaacc agaaaactgt aaagcatttg
     7921 atggtgttga aaaaggtctt gcgttgcagc acgtagattt tggttattct ccagaaaaac
     7981 tagtcttgaa agatgtctcg atcaatgtgg acaaaggaga aatggttgct cttgttggtc
     8041 caacaggatc ggggaaaacg acgatcatga atctgctaaa ccgtttttac gatgtcaatg
     8101 atggttcagt agtcatcgat ggaatagata tccgagatta tgatcttgat gcattacgta
     8161 gacatgtagg aatcgttttg caagaatctg tattgttctc cggaacgatc aaagacaata
     8221 tcacattcgg caaaccggac gcttcagatg aagaagtcat caatgcagca aaacaagcga
     8281 atattcatga cttcatcatg acgttagaaa aaggttatga tacagagata tccgaagaaa
     8341 ataacttatt cagtacaggt caaaagcagt tgatcagtat tgctcgaacg atcatcacaa
     8401 atccatcttt attgattttg gatgaagcaa caagtaatgt agacacggta acagaagcaa
     8461 ggatccaaaa agcaatggat gaagcaatca aaggaagaac cagctttgtg attgctcacc
     8521 ggctgaaaac aatcttgaat gcagatagaa tcgttgtctt gcgtgatggg gaagtcattg
     8581 aagaaggcag tcatcacgag ttattagcag aaaatggatt ttatgcggaa ctttatcata
     8641 atcaatttgt atttgaaagt taaattaaaa gaacctcgtt ataacggggt tctttttata
     8701 tattttatgt tgtttgtttt tataaggggc agaaaagggg caatttaaat ttctattttt
     8761 cctagttttt ctactagttg attttgcata tttttagttg tatgagtata aatctttaat
     8821 gttgtttttg aatcttcatg tcctacacga tccataatgg cttttaatgg gattcctaat
     8881 tctgtaagta gagaaatgtg ggaatgcctt aacatgtgag aagaaacttt tttatctagg
     8941 tttaattctt tggatactgc tcttaaagat tgattatatg ctt
//
LOCUS       DAFLVO010000094         8831 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.096, whole genome shotgun sequence.
ACCESSION   DAFLVO010000094 DAFLVO010000000
VERSION     DAFLVO010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8831
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.096"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(429..2810)
                     /locus_tag="L1U99_002538"
     CDS             complement(429..2810)
                     /locus_tag="L1U99_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBN1213053.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(2800..3447)
                     /gene="recU"
                     /locus_tag="L1U99_002539"
     CDS             complement(2800..3447)
                     /gene="recU"
                     /locus_tag="L1U99_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HBN1213054.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            3511..4050
                     /locus_tag="L1U99_002540"
     CDS             3511..4050
                     /locus_tag="L1U99_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HBN1213055.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            4140..4559
                     /gene="gpsB"
                     /locus_tag="L1U99_002541"
     CDS             4140..4559
                     /gene="gpsB"
                     /locus_tag="L1U99_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HBN1213056.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            4581..4948
                     /gene="rnpB"
                     /locus_tag="L1U99_002542"
     ncRNA           4581..4948
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="L1U99_002542"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            5157..6323
                     /locus_tag="L1U99_002543"
     CDS             5157..6323
                     /locus_tag="L1U99_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBN1213057.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            6369..7865
                     /locus_tag="L1U99_002544"
     CDS             6369..7865
                     /locus_tag="L1U99_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HBN1213058.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            7946..8629
                     /locus_tag="L1U99_002545"
     CDS             7946..8629
                     /locus_tag="L1U99_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBN1213059.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
BASE COUNT         2790 a         1590 c         1863 g         2588 t
ORIGIN      
        1 agctttttta ttcttggaat aacgaggtat tgttttcgat aaaaaaagat ggtgcagaca
       61 aattatgata attaagcata ctatcagata actcaaaatg aagccttctt tcaaaaaatt
      121 attcaaaacc atatattgta ttttttattt gataataaca atgggattat taagaagtgg
      181 cactaaataa aagactagtg tgtatttagc cgatttaatt ataaacaagt aaatggataa
      241 agtatatgta atgataaaag aaaaatggat tttctaattt ttaagctaaa tgttagatca
      301 cacatgtata tgctggatag tcttataaaa aatcatgtaa tacagcttgg tacatgattt
      361 ttatttgtag ctgtttttta catagacaca aaaaagaaac cacgcttgta gacgtggttt
      421 cttttttact atctgtttcc agaagctgag gtgctgctgg atggtgtatg gtcatttgca
      481 gcatccgctc cgctagttgc tggctcactg gaagaagcag gaggagcaga tgaagacggt
      541 gtcgagcttt cttcggatga agaagaagga accgttgttg aagacgctgg ctcgcttgtt
      601 tctgctgtcg tgctttcttt tgaggactca gcagttgatt cgctttgact agtagagcta
      661 gagctttgag tcgttgtctc tgttgttgag cttccaggag tctggacata gctggaagat
      721 ggaatagttg ttgatggtgt aattgcattc gatctagctg tatattgatc tttgtagtac
      781 agttcaccgc ccacacgaat taatccgctt ggcatctccc agtctgtatt tgtcacgtta
      841 gctgaaacat actgcataag ctcgcgataa acatcagagg ctacgtgtga cgattctgaa
      901 gtgacaggcg tcattttttt attgtaacct gtccacacgg aaatcgaata atttggcgta
      961 tagcccgcaa ataggatatc tggatacacc ccagaagaaa taccaagttt tgcatactcg
     1021 tcatctgtgt aattggatgt tccggtctta ccggcttgat ataacccagc gatttgcgca
     1081 ttcgtaccag ttccttcagt gatcgtatct tttaaaatgt ctgtgatcat ataagctgtt
     1141 tctggagaca tggctgtttt tccatctggc tcataagttt cttctgttcc gtcttggaag
     1201 acgattttat taacatattg aggtttgtaa taagtccctc cattggcgaa agccgcatag
     1261 gctgctgcca tttttaagga agaagctccg tattttgtcc catcttgttc ttccgtatta
     1321 ctagagatcg cattcgattg atggatcgta ctgtattcga tcccaagatt ttttaagaaa
     1381 gaagccactt tatctgaacc gacttcattg aataatttga ctgctggaac attacgggat
     1441 aagtaaagtg cttggcgtaa agtaatggtg cccatatatt gattatccca gtttcctaca
     1501 ggagtcgaag tcccttcata gttatacggt gcgtcagtaa tagtttttcc agtagaatat
     1561 ttcaaatatt caaaagctgg tccgtaatct gtgacaggtt tcatcgtaga accaaaatca
     1621 cgggaagtat tcactgctaa gttgttgcct aaagttacgt cttctgcgat gtgacgtccg
     1681 ccaatctggg cttttacttt cccggtattg gtgtcgataa gggtggaggc aacttgcatc
     1741 tcgtcgtctg ggtaagagac atactgatcc gtgttgacga tatcatatag tttcttttgg
     1801 gcgtccagat ccaaattcgt ataaatctct aaaccgtctg tgtagacatt cttatctgtt
     1861 ttttcttgta cttcattgat gacttctttg acataattat cgacgatctt agtattgtca
     1921 tcggattgag ttagttcttg cagaccatcc gttaccggta cattaacagc ttgatcatat
     1981 tctgtttgag agattttttc gttttgaagc atcgtataca aaacagtatc tcgtcttttc
     2041 ttcgcctgat ctggataaac ataaggatca taggcggaag gggcttgagg catcccagca
     2101 agcaatgctg tttgcggtaa agaaagttct gataatttct taccaaagta catctcagaa
     2161 gctgtctcca tcccgtacaa gccgtttgac atatacactt tatttacgta gtaggtcaag
     2221 atctcttgtt tcgatttttt ttgttccaat cttacagcca tccacgcttc ttgggccttg
     2281 cgtttcagag tctgatcctc ggcactggtg gagaagaagg aaagtttgat caattgctgt
     2341 gtcaaagtac ttccgccttg cagtccgcca gaggtaaagt tagagagggc agaaccgatg
     2401 atccgaatag ggtcaacccc gatgtgttta taaaaacggc gatcttctac cgacacgatc
     2461 gcatcttcta atgttttcgg taattcattc gcagaaattt tttcacgctt ttctgcgcct
     2521 aaatcttcga atagttcgcc atcttgtgta tatagtttgg aagatacggt agcgtctaat
     2581 tttttatccg tcaattcggg cgcatctttt gcgtaatacc agaaaagtcc tacacctgct
     2641 aaaaagagga tacagaaaaa tgagagtatt cctaaaagga tcttgataaa taatcctttt
     2701 ttatgtgttc cagaggactt tccagaacct ttgccagaat tcttcttcac actcttttta
     2761 ggagtaggct gtttctgtcg tctagagctt ctagtttgtt catttgccat tcttgctttc
     2821 tccttcaata gataatgttg ataaatagaa gtcaaccgcg tccaaataag gaatccgcgg
     2881 agaaatacca gttttgatct ctattcctag ttcttcgatc aaagataaag gtagtgattt
     2941 gcgtcctttt tccttttggg cgtcccagta agcaatcaaa tgaacactat tcaaataaaa
     3001 acagcgcttc aaagacgaaa accataacaa gacaaagcag accccatttt gttcgaggca
     3061 tgctttcata tgttcgattt gatgggcatg gaagttttta aagggaaaag atgttttgtt
     3121 cttggtttct tttgcttcaa agtccaagta aaagcctcga tagacgccat tatagtctgt
     3181 agttgaggct tgggtaaagt aggcttcctt gatcacagca gcacttctct taggatagtc
     3241 tactttcacg atttggatag gggtaggctt tttatggata accgccaacc cgcgggaaag
     3301 ataatattta ttactttcat tgattgcttc ttcaaagcgc atcccccgat tgccgaattc
     3361 agtgatctga tttctttttt cttgaatttt ttcgacggga gaggcattct tataataagg
     3421 ttggccattt ggatagcgca ataccatctt taatcacact cctaggccac attatagcaa
     3481 aaaagcggat agaaagaaaa ggaatctgag atggataagt caaaagtaat ctatgtgtct
     3541 gggtatcgaa gtttcgaact cggtgttttt aaagaaaatg atcctaaaat ccaagttgtt
     3601 aaaaatgttt taaaaaaaga actccatcag ttagcagaag aagggctgga atgggtactt
     3661 gtcagtggga atttgggcgt cgaactatgg gctgtgcaaa tagtagcgga attgaaagaa
     3721 gaatatccgg aactatctct tggtattttg tatccttttt ctgattttgg taataactgg
     3781 aatgaaggga accaagaaaa aaaacaatta gcagaacaat tagcagatta tgtcgaagct
     3841 gttagccatc aaccctacca atcacctagt cagctaaaga atcacactcg ttttatactt
     3901 gagcatacag tgggctgtct gctgatctat gatgaagaat tccctggaaa aacgaagtat
     3961 ttttttgaag atgcacagaa ttaccaagca gatcatccct acgaaattcg gctgatcagt
     4021 atggacgatc ttcaaaattt tagtgaataa tcgatattgt gtttgattta tcaacttttt
     4081 tcctatacaa tgaaaaaggt agaaatgtta ttacgtaaat gaaaactaga ggtgtaaata
     4141 tggcgaattt ggtttatagt cctaaagaca ttttacaaca agaattcaaa acaaaaatgc
     4201 gcggctatga tcccgttgaa gttgatgaat tcttagacaa tatcatcaaa gattatgaaa
     4261 cttacagcaa agaactcctt gctttacaag aagaaaacga tcgattgagt gcaaaagtag
     4321 ctcaattatc taaaactcaa ggagcagctc aaacacgcgt gcaacaaaca gaggcaccaa
     4381 agagcgcagc agtgaccaat tttgatatct taaaacgctt gtcaaatctt gaacgtgaag
     4441 tatttggtaa aaagcttgat caacaagcaa gtgcagtcaa accagcacaa cctaatccaa
     4501 ataactacac aaatgcagac acaagcttag atgataatga aaaaacacgt caattttaat
     4561 ttttgattaa tgaatttgcg gttttcgggt aatcgcggtc tgacttgatc aggctgagga
     4621 aagtccatgc tcgcacaggc tgtgatgcct gtagtgttcg tgcttagcga aaccataagc
     4681 taaggtactc tttggagtaa cggcaggaaa acaagctaag gcttcggcta tgcttaagta
     4741 tccttgaaag tgccacagtg acgaagcggc tggggaaacc catccggtgg aacgcggtaa
     4801 acccctcgag cgagcaaccc aaacaatggt aggggcgctt tttgtctgga agaagaacag
     4861 gacaaaaagg cagtataact gcagatagat ggttaccgct ttgttttttc tccctggaaa
     4921 agcaaagtac agaacatggc ttatagaaaa ccgcaaacat cagggaatta ggtcgtgaca
     4981 aaagtaatgc gttataagaa acaagaaaaa catttgaaag ctatttttca atacttcaga
     5041 tgaatcgttc ttattacaaa acaaactttt gtatcaccgg ttattcggaa tttgagtaaa
     5101 agtgtggggt aggactgatg tcccacctcc tttttttata aataaggaga ttgtgtatgg
     5161 aaaaaaacag gaagttcaac ctcgtcgcaa ctgcggcaag cgggctagaa gcactggttg
     5221 gtaaagaatt aagagatctt ggaatcgaat gccaagttga gaacggacgt gcacgttttg
     5281 aaggaacaat ggaaacgatc gctacagcta atttatggtt acgtacagca gatcgagtaa
     5341 aaatcgtggt tggggaattc gatgcgtata cgtttgatga attgtttgaa aacgtaaaag
     5401 cattgccttg ggaagatttt cttccactag atgcagcttt tcctgtagct ggaaaatcga
     5461 tcaagtcgaa actatatagc acacctgatt gccaagcgat cacaaaaaaa gcaatcgttg
     5521 aacgtctccg tacctattat caccgtccag cttctgtacc actgacggaa actggcgcac
     5581 attttcagtt ggaagtagct ttgctgaaag accatgtgat ggtaactctg gatacgacag
     5641 gaccaagttt attcaaacgt ggttatcgct tagaaaaagg tggagcacca ttgaaagaaa
     5701 acatggcagc agcacttatt atgttgacaa attggcgaaa agaccgtcca ttttatgatc
     5761 ctgtatgtgg ttcaggtacg ctttgtattg aagcagcctt aataggccat aatatcgcac
     5821 caggattcaa tcgtgagttt gcttgcgaat cttgggattg gttcagtcaa gaaatcatgg
     5881 aaaatgttcg atcagcagcc gaagaaaaag cagattatga tattgaatta gatattactg
     5941 gttcagatat caatggacgg atgattgaaa ttgccaaagc caatgcagaa gaaatcggat
     6001 taggctcttc gattaccttt aagcaacaag cagtcaaaga cttcaaaacg gataaagaat
     6061 acggggtcat cgtggctaat ccgccttacg gagaacgtct aggagaagaa gaaactgttc
     6121 ggaaattata taaagaaatg ggcgatgtat tccgtccatt aaaaacatgg agtaaatata
     6181 tcttgactag cgacttagcg tttgaggaat tttacggaca aaaagcaacc aaaaaaagaa
     6241 aattgtacaa tggtgcattg cgtacggatc tattccagta ttggggaact cgtccgccta
     6301 gaaaaaaaga gaaagacgaa taatcttact aattgattca ttcaattgga tgtttggagg
     6361 aatagggaat gaaagaaaaa gagtttttac aagaagtaaa agaaatcaat cttctacaac
     6421 aagctttagg aatcctcgat tgggatacac aaacaggtat gcctgaaaaa gctagtgcat
     6481 accgaagtga agtagacagc tatctttaca gcatttattt ttcaaaaaaa atcggtccaa
     6541 aaatcaaaga agccattcgc tatttttctg aacatccgga agaattgtcg gaagttggaa
     6601 ctgccgtttt tgccaaagta aaagaagagt atgatttgga acatcgcgta ccggaagatc
     6661 ttatgagaaa atatacagct gccgtttctt cagcacacgg acaatggcaa aaagctagag
     6721 aaacacaaca attttctgat tttcaacacg cattgaatca aaatattgaa ttaacaaaac
     6781 agttgatacc ttactggaga aaagatgaaa agacgaatta tgatgttttg ctgaatcaat
     6841 acgaacccgg gatgactgtc gaaatccttg ataaggtatt tgatcagctt aaagaaggaa
     6901 ttctttcgat ccgccgtacg ctccaagaaa aagggactga acctgaaaca gactttttaa
     6961 atcggagaat gacgaaaaaa caacagaaga gatttgtagt gaaagtaatc gaacaacttg
     7021 gttatgattt tagtcgtggt cgtttagatg acactgtcca cccatttatg actggaatta
     7081 atccgaatga tgcacgaatc acgacacgat ggaacgaaac agatttcaaa atggctgttt
     7141 ttggagtgat ccacgaggct ggtcatggta tgtatgaaca agacatcgat gataaatatg
     7201 cgtatacacc ggtttatgaa ggtacatcaa tgggtatcca tgaatcacaa tcgttgttta
     7261 acgagatcat tattggaagt agtcgcagct tctggaaaaa gcaatatcct ttctttcaag
     7321 aatgtgcaga aggaacattc gatgatattc cttttgacaa attttatcgt tcattgaacc
     7381 atacaaaatc aagtttggtt cgtatcgagg cagacagttt gacttaccct ctccatatca
     7441 tcattcgtta tgaaatcgaa aaaatgattt tcaatgaagg ggtagatgtt gctgaactac
     7501 ctgaaatatg gaatcaaaaa tatgaagagt atctgggaat acgaccaaca aatgatgtgg
     7561 aaggcatcct acaagacgtt cattggtcag gtgcaagctt tggttatttt ccctcttatg
     7621 cattagggta catgtatgcg gcacaattac ttcattcttt gcagcaagaa atagatgtgg
     7681 aaaatgttct agcgtcagac gattattctc caatcaaaaa ctggatgtca gagcatatcc
     7741 atcaatatgg tgcatctaga aaaccaaatc aattaatcat ggatgcaaca catgaaccgc
     7801 ttaatccgca atacctgatc gactatatga aagacctgta ttttaatgta tatcaggtaa
     7861 aataaaatac aatttacaaa gatagctgaa attcatctaa tctatagatg ttttcagcta
     7921 tttacttaag aaagaagtgg aacgaatgga taaattacaa gtgatcgctg attatagtat
     7981 ggaccaatta gcgcatgatc aaacaggaca tgggagcgat cataccaaaa gagttgtcaa
     8041 gttagctgaa aaaattttgg agacggaacc gcaggcagac cgctttgtga cgcttgcagc
     8101 agcttaccta catgatacga ttgatgataa agtcgttaaa aatgagaacg aggcaaagca
     8161 acagcttcgt gtattccttc gctctttgcc aatagtagag gaacagatct cgatgatttt
     8221 ttccattatc gaaaatatgt ccttttctaa aaatctctct gaagcggccg aactatctct
     8281 ggaaggtaag atcgttcaag acgctgatcg tatcgaagca ttaggagcaa tcggcatttt
     8341 gcgtactgct tatttcggcg gtggacatgg gcacccgatt tttgatcctg aactgtatcc
     8401 gcaaacattc aaggacaaag aaaattaccg aaaaggcacg acagtgatca atcattttta
     8461 tgaaaaactg ttcttgctgt ctgataaaat gaatactgat tacggatatg aagaagccaa
     8521 acgaagagaa accttcatgc gtgaattctt agaagaattt tttctggaat ggtctattga
     8581 cgatgaaaat tttactccag acaattggat caaaaataac aaaaaatgat ggaggttgtg
     8641 acagaagtgg tcagctccaa gatatttcgg atcattttcc gtaaaagtta cttctggaac
     8701 actgtttacc aagaggtcgt gagcctgccg ttcagctccg agtcacaagg aacaatttca
     8761 aaaaatagct tctcgtgttt gatgaatatt gtaacttgtg attcggaatt ggcaggagaa
     8821 caccgtttat t
//
LOCUS       DAFLVO010000095         8818 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.097, whole genome shotgun sequence.
ACCESSION   DAFLVO010000095 DAFLVO010000000
VERSION     DAFLVO010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8818
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.097"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(943..1356)
                     /locus_tag="L1U99_002546"
     CDS             complement(943..1356)
                     /locus_tag="L1U99_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HBN1213060.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1812..2297)
                     /locus_tag="L1U99_002547"
     CDS             complement(1812..2297)
                     /locus_tag="L1U99_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213061.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2436..2651)
                     /locus_tag="L1U99_002548"
     CDS             complement(2436..2651)
                     /locus_tag="L1U99_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBN1213062.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2875..3675
                     /locus_tag="L1U99_002549"
     CDS             2875..3675
                     /locus_tag="L1U99_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1213063.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3694..5562
                     /locus_tag="L1U99_002550"
     CDS             3694..5562
                     /locus_tag="L1U99_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBN1213064.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5555..6046
                     /locus_tag="L1U99_002551"
     CDS             5555..6046
                     /locus_tag="L1U99_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBN1213065.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6034..6588
                     /gene="srlA"
                     /locus_tag="L1U99_002552"
     CDS             6034..6588
                     /gene="srlA"
                     /locus_tag="L1U99_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBN1213066.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6606..7601
                     /locus_tag="L1U99_002553"
     CDS             6606..7601
                     /locus_tag="L1U99_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBN1213067.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
     gene            complement(7743..>8818)
                     /locus_tag="L1U99_002554"
     CDS             complement(7743..>8818)
                     /locus_tag="L1U99_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBN1213068.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT         3046 a         1425 c         1683 g         2664 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatttca tctaatacga tacaaaggct atctttctaa tttgaaaaag
     1501 ggatcattaa aataataaga agaaaatatg tcaaaaggta aaaaagtaaa ttcttctatc
     1561 caaatataga aaaattgaat ctagaaaacc gcccgacaat aaatttcatt aactcagttg
     1621 accgaaaatg aagtagatac caaaaattta tcaagagagc aagtagagaa gtgagtatat
     1681 tcataagaga aatagctgta acgaattatt aggttaatgc aaatgcttat ttatactccg
     1741 tataactttc tcagaaaaaa tgataccaat aatgacttgc tagtactgta aatccgtata
     1801 atatcatcta atcaaaatgg tgttccattt gcatctgtca tcgtaatcga tccttcgggt
     1861 gacactcgat aaaaaccaac gcttccagat cctccttggg aacggatttg tttgctggaa
     1921 gctgtgaaca aataatctcg atcaattttt tgataaaagc taataacaat atcgtcactt
     1981 tgtaattcgg aacggtgggc aataagaaat agaagtgctt tgtcagagtt ttctaatgga
     2041 agagaaggta cagtgctttc ttgcatttca gatgttgaag aaatgctaaa cgactgaata
     2101 cttgattggc tatgttgcga atctacatta ccagtagaag tattagtaat ggaagtagta
     2161 gaagtacttt tagttgaacc aacctcagtt gttgaaatgg ctgctgaaga ttctttaaca
     2221 gaattctttg ttttatatcc acaggcagaa aaaagtatta cagttcccaa caagcctgcg
     2281 taaatccctt tatgcatgat agctcctcct aaaatagatt atctttattc agtatatcac
     2341 ttaaacaaag aaaagcagat ggtttaaaat gaaaaaacct tcccaataaa gggaaggttc
     2401 atgaagataa taactttttt aataattata gctttctaat atctttcatc aacttttcta
     2461 gtaatcattg ggaaaaattt caagcagtag atcgcacaaa tacctacgac gatataaatg
     2521 atcttcgcaa aaatagttgt tgaaccacca gcaatcatag ctactaaatc aagttcgaac
     2581 aagcctacca acagccagtt caaccctccc acaatcaata aagttaatgc aatagcatct
     2641 aaagttttca ttagaattct cctttcttaa atgataaaac aattatatat caaaaagaga
     2701 aacattgctt atataacgct caggaatttt agcaatctat gcaaaaagat gaaaattttt
     2761 tttgctcttc cattagtaca cattttttag ctgaagctgt aaatttcatg tcttaatttt
     2821 ttttagtgag cttttatact ggatttgtaa gaaaaaagaa ggagaggatc acatatgtcg
     2881 gattggttgg atattgcagg aaaagtagta attgtaactg gaggttcctc aggaattgga
     2941 agaagtatcg tcgaaaattt gttgaagcag aatgcacaag tagcgaattt tgatgtaact
     3001 gaatgccgta tacagcatga aaacctacta tctttaaaag tcgatgtgtc ttctaaaacg
     3061 gacatagaag aagggatata taaagtaatg aaacatttca agacgatcga tggtctagtc
     3121 aataatgcag gaataaatat tccttctctt ctaatagata gaaatcatcc aaaaagcaag
     3181 tatgaattat cagaacaagt ttttgataag atgatcgctg tcaatcaaaa aagtgtatat
     3241 ttgatgagcc aagcagttgg aagaatcttg gtgcaaaagg gatcaggagt gatcgtgaat
     3301 ctttcttctg aatcaggatt ggaaggatca gaaggacaga gctgttatgc tgctacaaaa
     3361 gcagcgatga acagttttac tcgttcttgg gcaaaagagt taggaaagag gaatgttcgt
     3421 gtggtaggtg ttgcaccagg gatactggaa gaaaccggtt tgagaacaca agaatatgaa
     3481 gaagctcttt cttatacgag aggtataagc gtcgaacagc tgagaaacgg ttacagtcga
     3541 acaagtacga tccctctagg aaggagtggt aagctgcaag aagtggcgga tctagtctgc
     3601 tattatcttt cagaaagatc aagttatatc actggagtca cgactaatat ttcaggaggt
     3661 aaaacaagag gataaaggat aggggggacg cacgtgacgc tagtaaacag atggtaccaa
     3721 ttattgaaat tactagtcac tcacaagaaa gtttcaatcc aggaagtgca aaaagaaatc
     3781 aaaaccagta atcaaaccat aaaaaaagat attggggagt tgaatgaaga aattgccggt
     3841 attgcaaaaa tcatccaaaa aaacaaacat tttgaacttg aaatttatga ttttgatttt
     3901 tttgatgaga tcatgcaagg aaaattgaaa acagccagtg atttcaattc ggcatccaaa
     3961 agaatcgctt atttactaaa taggctgatc gaaacagagg atttcttacg tatggatgat
     4021 ttgtctgaag aagtcggtgt cagcagagga acagtggtca aggatctaaa gacattaaaa
     4081 gagatgatca atgattttga tgtaaagatt acaggcacac caaataaagg actaagaata
     4141 ataggagatg agctagaatt acgactactt ttattttatt ttgtttctcc ctacttttca
     4201 gagacgaaaa cagaacagtt tctagaagaa aaacaagcaa tcaaacattt tcagaagaag
     4261 acgaatgcta gtaaacaaga aatcaccctt ttaacgaaag ttatcggtat ttctttgaat
     4321 agaatctcta gtaactatct gttgaagaag cccatcaatc gttacagtgg gtgttttgaa
     4381 tatatccaag aattcaatga actgatcaat cagttggaag aaatctatga actaactttg
     4441 agccaatatg aaaaagattt tatcagtttt cctttgaaca tcatcaacac aagtataacg
     4501 atgataagga aagctaactc tgatttgcgc ttatatttcg accccatgat gatgcgtatt
     4561 cgacgattag atctcattga tctggatgag tccttcttat atcaagagat gaaacagcac
     4621 ctctctttat tgataaatcg ggtaattttt cgttatcgat tgactgattt attttatggt
     4681 gagatagaaa aaaagtatcc tttttcttac caaatcgcta gcgaatgcat acaagcatta
     4741 gaagctatct tgcaacataa gatctctaaa gtagagatca gctacctaac gttgtatttg
     4801 gagttagcat ttcgatatca aaaagagcat ttttcctcta aaaaagtagc cattgttcat
     4861 acgacaggaa aaggaacagc attaatgatc caaagacaaa tcaaaaggat attggggagg
     4921 gatatacaaa taacacatgt ttcagaagaa caatatgaaa aagtagatct aaacaaatat
     4981 ttcgctgttt ttacaacgat tccgttaaaa aatgtaaatg aagagacacc ggtgatccat
     5041 ttgactaatc tttttgatga ctcttggtta agggcacaat ggcaaaaagc aaaaaaaaag
     5101 cgattagccg ggtttcattc tactgttttt ttctatcaaa tatggaaaga aaaaaagacg
     5161 tatcaagaat atttaaacaa attagtcgct cctttgatca gaggctatta tgtggatgaa
     5221 gaatttgaaa aaaggatctt gaaaagagaa tatcagcaaa gcacatttgt taacaaagaa
     5281 tttgcttttc ctcacacaac caaccagcta tctcaacaca ttgttttatc agtagggcta
     5341 ataactgatc aaggtttagc agaaacagga ggaaatggag ttattttttt atttgccata
     5401 cctgaagaaa tgacggctga agttgagaat gaattatttg agctatacga tatcctattt
     5461 gaactcataa aaatgggaat agatgagttt attgaattag caccgacaca agaatcattt
     5521 ttaaaactaa tcaaaagtaa aggagagaga cttcatgaat gatatgtatc tattcatagt
     5581 tttcgcagct tcagcttatg tgctgcaagc agttatcagt tggaagcaac taaagcattt
     5641 caatcaaaca tatagcgaac tgcgaagaaa aggaaaagta gcgattggta aacgacctgg
     5701 gaaaatccgt tcaggcacga ttgttatgct agctatagac gatcatgatc aagttttaga
     5761 agtcagaaaa atgcaagggg ttacatcttt ggcaaaattt cattcattac ctgtctatgc
     5821 gggtgaagat atccattaca tcgatcgtta ccatccctca gttcgagcgg aagatcgttt
     5881 gacacaagca gctttagaaa atgccagaga agtatactta cgaatagagg caggaaatga
     5941 aaaaagtgaa caaccttcat tgccttttat tgctatgctc aataattttc ggatatggaa
     6001 aagtacgatc aaagaaaaaa ggagtgacaa acgatggata tcataacaaa atttgctgag
     6061 ggatttatga ggctgttcca aacaggtgca gaaacattca taagctggat gacaggaatc
     6121 gtaccagttg tcttgatgct gatggttgca atgaatacgc tgattgcttt tttaggtgaa
     6181 gaccgagtaa cgaaagtagc caaattatca gcgaaaaatc cgcttactcg ttaccttgtg
     6241 ttaccgttct tatctgcttt tatgttggga aatcctatgt catttacaat ggctcgtttc
     6301 cttccagaat actacaaacc aagctattat gctgctcaag ctcaattttg tcatacgagc
     6361 aatggtgtat tcccccatat taatcctgga gaattgtttg tatggatggg gattgctcaa
     6421 gggatcgaaa ccttagggct aaattcgatg gagctggcta tccgatactt gcttgtggga
     6481 ctgctgatga actttattgg tggttggata actgatttta ctactggatt tgtatgcaga
     6541 cagcaaggaa tcgttcttag caaaaaagta gagctttcag ttgattagag aaaggagagt
     6601 tttaaatgta tggtgatatt aagatcgtaa gaggaaacgg cgggtatgga ggtcctttga
     6661 ttattaggcc gacaaaagat aaacacaagt tcatctatgt cacaggtgga ggtgagaggc
     6721 caatgatcgt agataaaata gaagaactga caggtatgga gtctatcaat gggttcaaaa
     6781 catcaatacc tgatagtgaa atcgcgcttg caatcgttga ctgtggaggg actcttagat
     6841 gtggaattta tcctaaaaaa gggataccaa ccatcaatat cgtttccaca ggaaaaagtg
     6901 gcccattagc acaatatatc actgaagata tttatgtttc agcagtaggg ttagaacaaa
     6961 tacagccact aatggaaact gatgataaca aagaaacagt aaatactgca tctccagata
     7021 aaaagtacaa atatgatact tctaaaaaga taaccgagca aaaagcagag cagcaaaact
     7081 ggatagcaaa aattggaatg ggcgcgggaa aagtagttgc tacattcaat caatcagcaa
     7141 gagaagcagt agatacgatg atccggacag tgatcccttt tatggctttc gtttcccttt
     7201 tgattggtgt gatacaaggt tctgggatcg gtaatgtatt tgctaacatt atggcacctt
     7261 tagcaggaaa tgcagttgga ttaacaatca ttggctttat ttgttcactg ccatttttat
     7321 ctcctttgct tggtccaggg gcagttatta gccaagtgat tggaacattg atcggtgtag
     7381 agattgggaa aggaaatatt cctccccaat tagcattacc ggcactattt gctatcaata
     7441 ctcaaaatgc atgtgatttt attccagtcg gtctaggttt ggaagaagca aaagctgaga
     7501 cagtagaagt aggtgtacca tcagttcttt attcaagatt tcttaacggc atcccacgag
     7561 ttatcattgc ttgggtagca agttttggat tatatagctg agtttagtct aatggtgata
     7621 agtcaagatg aaatttaaga ttttctttat tgagtaatat gttttgaagc gcacgaaact
     7681 agacccgatc aaaatcaaat ttttttcggg ttgattcaag gatttgcgtc aataacggat
     7741 tgttatttct ctatcacact ccttggtggc gtatagagtt ggtgtttacg tagtagcgta
     7801 tccaccagac gcgtaaattt tcttgcggtt aggacgagtg cacgtttgtg ttgatgcttt
     7861 ggaacctcct tatatttact ttgataaaaa gctttgtatt caggaagata attttttaca
     7921 gagttggcag cttcaactaa gtagtatcta aaatatcgat ttccttgttt tgtcagaggt
     7981 gtattttgcg actgatagtt tccagattgg ttcactttcc aacttaatcc agcgtatttt
     8041 gccaattttg tctgatcttc aaatctttcg atttgaccaa tttcagcgat taaaccggca
     8101 gcatagactt taccaacgcc tggaatactg gttaagcatt gatattctgg aatgacaaca
     8161 attacttgtt cgatggcttt atctaattct ttgatatttt tttcaagtgc tcgtatttct
     8221 cgtacgagaa cacttaaaac aacattaatt gattcttgtg caagagcacc taggcggtaa
     8281 ctcatggtaa ttgcacgttg aattgcttta gcgatttttt ctggttgctt gaaacggcct
     8341 tttccttttt cttgaagtaa atcacagaaa gcttctaaag gaagctcagc aagttcatcc
     8401 aatgtgaaat cttccgtcat gagtgaaatg agggttgcac taaaaagact cgtcgattcg
     8461 tctcgcattt ctcgagcaag cgtattacat ttgtacgtta gattttcaag aaaatgttgc
     8521 tttgtacgaa tcaattgctt aataagttga tagcgagtac gtgttaaacg ctgtaaggcc
     8581 atgtatttct cttctttgat aggggaagtt gtgaatcgtt gaatacgcaa gaaatcagcg
     8641 attcttaatg catcgtttcg atcagtttta ttctcatcaa acatgcgact aaattgtttc
     8701 acccgaaaag gattttcaat cgttacaagt gtgttgagct tctttagttt ctcatcttca
     8761 tgaaaaaaca tggaaggatg gaagctgtac atggacgttg actccatgcc aatcacaa
//
LOCUS       DAFLVO010000096         8767 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.098, whole genome shotgun sequence.
ACCESSION   DAFLVO010000096 DAFLVO010000000
VERSION     DAFLVO010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8767
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.098"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            437..883
                     /locus_tag="L1U99_002555"
     CDS             437..883
                     /locus_tag="L1U99_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBN1213069.1"
                     /translation="MKDYVVQITKEVLEESKTLNKLSSKAKEEAVTILSSGIIDYIEM
                     SGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSYLIGKLINILGTDEDTELFLSSLS
                     MIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREKTPDEFYDWFEK"
     gene            1507..2499
                     /locus_tag="L1U99_002556"
     CDS             1507..2499
                     /locus_tag="L1U99_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1213070.1"
                     /translation="MYWEEIELEKTLGPGGEIRAVQRDKKNISKWEKLKKQLRRDKWM
                     YLLLLPGIIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLL
                     LSNTLKISIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLF
                     LFLSANGPINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVS
                     TDLYEAANIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNI
                     PASEIISTYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            2515..3399
                     /locus_tag="L1U99_002557"
     CDS             2515..3399
                     /locus_tag="L1U99_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1213071.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTIQGYQRVFADDSILRGFVNSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            3448..5055
                     /locus_tag="L1U99_002558"
     CDS             3448..5055
                     /locus_tag="L1U99_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1213072.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSKSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFAEKRNLDIASGDLP
                     DAIFNAAAGDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SMPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLPVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTVTTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            5056..6540
                     /locus_tag="L1U99_002559"
     CDS             5056..6540
                     /locus_tag="L1U99_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HBN1213073.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPIGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYSGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDGYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTRDPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            6717..7709
                     /locus_tag="L1U99_002560"
     CDS             6717..7709
                     /locus_tag="L1U99_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1213074.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPDIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGDTTKPLVRNDFA"
     gene            7761..8630
                     /locus_tag="L1U99_002561"
     CDS             7761..8630
                     /locus_tag="L1U99_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1213075.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMEQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGKIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQSFKEKMGSYVDTPTLEEYLLTPRLADNAGL
                     IGCLALAIKKLNH"
BASE COUNT         2836 a         1367 c         1912 g         2652 t
ORIGIN      
        1 gataaggagg aatttgaata tgtttggttt agtacaacct aataaagtga aggtgggcca
       61 acgaatcaaa gaaataaaag acggaatgtc tctctctttt acagaattag ggaatcgatt
      121 aggtttaaaa aagccgacga tcagttccta cgttcaaggc tatgcgttgg ctcctaagag
      181 tgtgatcaac caattatcta gtatcagcgg aaaacctgtc ggctggtttt attttgggca
      241 tgtggaagaa tatatccgag agtatttgtt tctcattggt cagaaaaaaa tagtggacga
      301 ttatcctgaa atcattgaga aaataaagca agaattttat acgggcgagt tcaaaaatcc
      361 tgcttgggag aatgagctag gctatccttt ggaggaattt atccaagaat gttttgtaga
      421 atattcgagt gaaatcatga aggactatgt cgtacagatt acgaaagagg tacttgaaga
      481 atccaaaacg ctaaacaaac tatcatcaaa agcaaaagaa gaagctgtca cgattctttc
      541 atctgggatc attgactata tcgagatgag tggtgagatc aagtatggag agaaagatcg
      601 cattgcgaaa atggtgaaag aatcaataaa aacctttgat gtgaaacaag acctgacatt
      661 taatgattcc tatttgattg gaaagttgat caatattctt ggtacagatg aagatacgga
      721 gctgtttctt tcttctttat caatgatatt tactgataag catttttcca ctcgatttgg
      781 tggggaagaa ttagtcgaaa tatttcaatc gatgcgacca gcgttaatca aactctatcg
      841 ggagaaaaca ccagatgaat tttatgattg gtttgagaag taaaataaga aaagtggctt
      901 agattacaag ttggtgaaaa aatttttttc agcataacat cagtaatcta taaaggggtt
      961 gttgattata ctgtagaagt taagtactca agagattttt tgtacgtaaa caaagcaaaa
     1021 aagggtgcag tttcactaga aaatgtactc ttttttgtga tttttcttag ttatagagtt
     1081 tttttgaaac tttaaaaatg agaaaacata ttgattttaa agagtgtaga catagcttct
     1141 tttgctaaat agattaaact tactggtgag tggtcttgaa catactttta aatcacattt
     1201 tactgagttt tattggattt tataattcat tggaaacctc gtacttaatc tgtttttatc
     1261 tatcgactag aatctgtata tattccagct atcaatgagg ccgcagaaaa gggtgcttaa
     1321 aaataatctg ttgtttaaaa tattattatc agaatactta gatacaaaat tctggcacaa
     1381 agtaaaaaaa atattgactt aaaaaaatgg atatggtaat ctataaacga aaatagtggt
     1441 aacgtttcca aaatgcatct tcgttaaatt tttatttttt taaacgaaaa tggaaacgtt
     1501 tctaaaatgt attgggagga gattgaattg gaaaagacat tgggaccagg tggtgagata
     1561 agggcggtac aacgggataa aaaaaatatt tcgaagtggg aaaaattaaa gaaacagttg
     1621 cggcgtgata agtggatgta cttgttgctc ttaccaggta tcatcatgac gtttatcttt
     1681 aagtatgtgc caatgtacgg tgctgtgatt gcatttaaag actataatcc tatgctagga
     1741 attttggaaa gtccttgggt aggactagat cactttaggg aatttatcag ttcaccaaat
     1801 tttacgcttt tgctgagcaa cacattaaaa attagtattt atggtttatt gttaggtttt
     1861 tttccaccaa ttattttagc actgagcttg aatcaaatta tcaataaaaa aataaaacag
     1921 aaaatccagt tgattctata tgcgccgaat tttatctcag tagttattat tgtggggatg
     1981 ctgtttttgt tcctatccgc aaatggacct attaatgggt tagtagaaaa ggttacgggg
     2041 caaccaatta tgttcatgtc taatccagct tatttcagaa cgatttatat tttatcggga
     2101 atttggcaag gaatcggctg gtcatccatt ctttacaccg caacgctggc gggagtcagt
     2161 accgatttat atgaggcagc aaatatcgat ggggcaaata ttttacaaaa gatttggcat
     2221 atcgatttgc ctgcattgag gcctgtgatg gtgatcagct tcatcttggc cgccggcggt
     2281 attatgaatg taggatatga aaaagcctac ttgatgcaaa cttcaatgaa catccctgcc
     2341 tcagaaatca tttccactta tgtatacaaa gtcggcttgc aatcaggtga ttatgcctac
     2401 tctgctgctg ttggtctgtt caatatgatt attaatgtcg ttttattact gattgtcaac
     2461 aatataacca agcggctaaa cgatggtcaa ggcttgtaat gaaaggagaa aattatgaat
     2521 agtgctttat caaaaatcga ccgtcaaatc ttatggttga atcgagtgat tgtaactttt
     2581 ttagtcgtca tcaccattgt tccgctgatt tatgtactgg tagcttcttt tatggaccca
     2641 gctactttga tcaataaagg tataagcttc aatccgaaag attggacaat acagggatat
     2701 caacgggtat ttgcagatga ttccatttta cgcggttttg taaattcgtt gttttactct
     2761 tttagcttca gcttattgac tgtatttatt acgatgatca ctgcgtatcc tttgtctcga
     2821 cctaacttgg cggggaaaaa gattattatg actttttttg tcattacaat gttcgtgggt
     2881 ggtggcttga tacctaccta tttattggta aagaacttgg gcatgttaga tagtgtatgg
     2941 gcgattatcg taccaggtgc tataaatgtg tggaatatta tcttagcccg tacctatttt
     3001 agtgctttgc caaaagaact ttctgaagct gctactatcg atggcgccaa tgacttgcaa
     3061 atactgttca aagtcatgct tccattagcg aaaccaatta tgttcgtatt gtttttatat
     3121 gcctttgttg ggcaatggaa ctcatacttt gatgccatga tttacatcaa agatcccgac
     3181 ttacagccgt tgcaactcgt attaagaaat attttgatcc aaaaccaacc ttcacaagac
     3241 atggtgggag ccaatactgc catggcagaa atgaaacaaa ttgctgagtt gatcaaatac
     3301 gcaacgatcg tcatttctag tctgccatta atcataatgt atcctttctt ccaaaaatat
     3361 tttgataaag gtgttttagt tggttctgtt aaagggtaag tattgttcac tatttgtatg
     3421 aataaaaatt ataaaggaga ttttaagatg aaagcaaaat ggatgctgcc aatcgttttt
     3481 acttccgtac taattttggg ggcttgtgga ggctcaaaag aaaagagtaa atcaagccct
     3541 gattatgaac tagaaaatgt ctcttttcca ttgaaagaaa aagtatcttt aaaaatgatg
     3601 tctcaaagtg cccctttggc tcccaatgat cctaatgaca aattgatttt ccaacgatta
     3661 gaagaagaga ccaatctcca tattgattgg acaaactaca gtagtgattt tgccgaaaaa
     3721 agaaatttgg atatcgctag tggtgattta ccagatgcca tcttcaacgc cgctgcaggt
     3781 gactatgatt tattaaactg ggcggaaagt ggcgttattg taccgattga agatttgatc
     3841 gaagattata tgccaaatct gaagaaaatt tttgatgaaa accccgaata ccgacaaatg
     3901 tctactgcac ctgatggtca catttactct atgccttgga ttgaagaatt aggcgaagga
     3961 aaagagtcga ttcatacagt aaatgggatg gcttggatca acaaggagtg gttggataat
     4021 ttgggtcttg aaatgccgca aaccactgat cagttgatga ctgtgttgga ggctttcaag
     4081 acgcaagatc caaatggtaa tggtgaagca gatgaaattc cttttagctt tattaacaat
     4141 ggaggaaacg aagacttaaa atttttaatg ggggcattcg gtctaggtga taatgatgac
     4201 cacttagtcg ttgataacga tggtcaggta caatttactg ctaacaaaga agggtataaa
     4261 gaagccatca aatatttcaa tgaaatgaat aataaaggtc ttattgataa agaggctttc
     4321 gaacaagatt ggaatacgta tgttgccaaa gggaaagaac ataagtatgg cgtgtacttt
     4381 acttgggata aagcaaatat cacgggtgca gatgatagtt atgacgtctt gccagtctta
     4441 gcgggaccag atggaacgaa acatgttact cgtacgaatg gcatgggttt ctcaagagat
     4501 cgtttcgtaa ttactagtgc gaataaaaac ttggaactta cagctaggtg gatagataaa
     4561 atgtatgaac cgttacagtc tgtccaaaat aactggggaa cctacggtga tgaagcacag
     4621 gcgaatattt ttgaattaaa ggatggtatg ttaaaacatt tgcctttaga ggggacagca
     4681 ccgggggaac taagacaaaa aaccgaagct ggaggaccat tagcagttct tgattcttat
     4741 tacggcacag tcactactat gccagatgat gcgaagtggc gtttagattt gatgcatgac
     4801 acgtatttgc catatattac agaagacaat atctatccac gtgtcttttt agaaaaagaa
     4861 gaaacagatc gattagcaaa aatcgaaacg gatatgtggg attacatcta tcgcaaaaga
     4921 gcagagtgga tcaccggcgg taaaatcgat gaagaatggg aagaatacct tgctgaattg
     4981 gaacgtgtag gtttggaaga atggattcaa ataaaacaaa ctggctatga taattttttg
     5041 aagggagcac aataagtgtt agtagaagaa acggcgattt tggataaagc aaatcgattt
     5101 attgaaatga tgcgaggaaa agttaaccct cagtatcgac aaaactatca tttttccgca
     5161 cccatcgggt ggataaatga ccccaatggg tttatatatt acaaagggca ttaccatctc
     5221 ttctatcaat actatcctta cgatagtcga tgggggccca tgcattgggg gcatgcgcgc
     5281 agtagtgatt tggtccattg ggaagatcta ccagtagcgt tagccccaga tcaaccttat
     5341 gacagcggcg ggtgtttctc aggaagtgca attgaaagag acggaaaact atatttattt
     5401 tatacaggct gtcaagaaat tgatggtatt agccatcagc atcaatgttt ggcggtctct
     5461 gaagatggta ttcattttag caaatacagt ggtaatcctg tggtagcaga aaaacagcta
     5521 ggtgaaaatg ggctaataca agaatttcgt gatcctaaag taattgttca caacgatggt
     5581 tactatatgg tagtagctac taaatctaca cagtctactg gtagaatagt gatgtttcaa
     5641 tcgtcagatt tgtatacttg gcacttttac tctgtgctgc tagaagggac ttcagagcaa
     5701 ggaataatgt gggaatgtcc tgatttattc catttagacg gacgagatgt cttaatcatg
     5761 tctccgatac aaatcaagaa gaacggactg gaatatcata atatcagttc taccatggct
     5821 tgtattggtg aggtaaactg ggaaacaggt cagatgatag ttgataattt ccatgaaatg
     5881 gattttggaa tggattttta tgcaccacaa acaacaagag atcctaatgg tggacgggtg
     5941 atgattgctt ggatgcagat gtgggatcgt acattgccta cacatgagtt aggccatctt
     6001 tgggcaggct ctatgagttt gccccgagag ttaagagtga aaaaaaatcg attggtacaa
     6061 aaacccatct caactgtata tagtcattta gtttatcaac aaggcagtga aaatattgca
     6121 gtgactgaca catcagtcgt atttcgaaac gcgctgtctg attcttcata tttacatcta
     6181 gtcgcagatt tggagaaagc tgaagttttt acaattgaat tactgcggtc taagacggat
     6241 tgtctcaaac tagcctatga cactgctaca caggtttttg aattggatcg tcagaaacta
     6301 ggaagagagc ttacaggggc ggaagaagac cctctgaatg tacgaaaagt tgaagtacct
     6361 ttgattgata atcagctcgt tcttgagatt tttagagata cctcatcaat tgaagtcttt
     6421 attaatgggt tagaagttat gacggctact ttctatgagc tggaaaaagc tcgagatatc
     6481 ttgtttcatt cgatcggaga aagtcgtatt caagcttttg aaacagcgag tgtgaaataa
     6541 atgtttgatt gcttaggcga tgaatcaatt atttaatagg tttggaagga taatgttttt
     6601 agaaaagaac agatagctag atttcccatg gatttgctat tagtattttg aaaaaattag
     6661 taatttatga caaaattcat tatactaaac ttgtgcagaa atgtgaggga tcaactatga
     6721 aagcaacaat gaaagatgtc gcaaaattag caggtgttgg agtaggaact gtttcccggg
     6781 tattgaataa cggttctgtt aaagcttcta ctagagaaaa agttgaagca gcaatgacag
     6841 agttaaacta tcaaccagat ttttatgccc gggggttaaa gatgaagcat acgaacacgg
     6901 ttgctttgat tctacccacg gtatggcatc cattttttgg cgaatttgcc taccatgtag
     6961 aaacagcatt agaaagacaa aactacaagc tttatttgtg taactccagt ggtaatagtg
     7021 aaaaagaaca agaatatatc cagatggtca gccaaaataa agtagacggc atcattggaa
     7081 ttacttattc agatatcgat gaatacattt cgagtaatct gccttttgtt agtattgacc
     7141 gttatttcac tgaagaggtg atttatgtga ccgctgacaa tgcggccggt ggacgtttgg
     7201 ctgcaaatga actttatcgc cgaggatgtc agaatgtagc atatatcggt gggtaccaag
     7261 aaacaccgaa tgaaacgaag agtcgtcgaa aatattttga aatcgagtgc cgtcaactgg
     7321 ggatttccta taaagcgtta gatatgttag aacctttaga ccatctctca gaacgtgtaa
     7381 caaatttttt gttagagaat cccgatatcg atgggatttt tacgatcaac gatccaatgg
     7441 cattagctgt cattgatatg cttgaaaaaa tagggaaaaa cgtaccagag gatgtccaag
     7501 ttatcggatt tgatggtcaa aagatgacag aaggagatcc ttatctagtc tcaacgattg
     7561 cccaacctac aaagcaaatg gcggaagtgg cagtggcaaa attaattgct gtcattaatg
     7621 gagagacagt agaaaaacgt accgtattgc cgattgaatt tggcgaaggt gacacaacga
     7681 aacctttagt gagaaacgat tttgcttagt gcaaatacgt ttcttttttt gaaaatgagt
     7741 gaatgaaagg tgtagataaa atgttatatg gtggaataga agccggtgga acaaagtttg
     7801 tctgtgggat tggtaatgaa caattacaag tgatagaacg gaaaagtttt cctaccacaa
     7861 caccagaaga aacgatggag caagtgtttg atttctttga taagtacaaa ggaaatatcg
     7921 catcaattgg tgtaggagca tttgggccta ttgatattca aatcgaatca agaacttacg
     7981 gatatatcac caacacaccg aagttagctt ggcaaaatta tcattttgta ggagctttgg
     8041 aaaacgcctt gtcggttccc atctattgga ctaccgatgt aaatgctgct tgttatggag
     8101 aatatatggc agggtatgga aaaggtaaaa atagtgttct gtattacacc gttggtacag
     8161 gtgttggtgg tggtgctgta gtggatggga aaatagtcgc aggttttagt catcctgaaa
     8221 tgggacatat gctcttacaa cgtcataatg aagatcaatt tgaaggaatc tgtccttttc
     8281 atcatgattg tttggaaggg ttagcatcag gacctgcgat tgaaaaacgc tttggaagaa
     8341 aagcccagac tatctcattt gatcatcctt attggacgat tgaggcagat tatcttgctc
     8401 agtgtgtgta taacacaacg ttactatatg caccggaagt aataatttta ggcgggggtg
     8461 taatgaaaca gccgcaacta ctcgagttga ttcgccaatc gtttaaagaa aaaatgggtt
     8521 cctacgtgga tacgcctact ctcgaagaat atctactaac tccaaggctt gctgacaatg
     8581 cgggcttgat tggctgccta gctttagcaa taaagaaact caatcattag aatagtattt
     8641 attagaacta ttcataacat accggaagtt taaaagggta ttctgaaact taaatagtct
     8701 caattcattc ttctttcttg agaatctgag tagagacttt tattctgttt caaattaata
     8761 taattac
//
LOCUS       DAFLVO010000097         8759 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.099, whole genome shotgun sequence.
ACCESSION   DAFLVO010000097 DAFLVO010000000
VERSION     DAFLVO010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8759
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.099"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..1185
                     /locus_tag="L1U99_002562"
     CDS             <1..1185
                     /locus_tag="L1U99_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBN1213076.1"
                     /translation="LSPTPRACRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPL
                     VTRLKKQRYTCKNCRTHWTAQSYFVRLSHSIADHVRYKIASLLTEKVSLSFIAKSCQV
                     SLTTVTRTLKEFKSYLPKPSKKILPRVLMVDEFRSHASIEDKMSFICADGETGNLIAV
                     LPTRKLPRLTSYFLGCTNPEEVEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMN
                     QALNELRIREMNELRKAGQKSQAEKLKKNWRFLLKNRASINHYEYKTWKSFRAPKYPF
                     LTEAMMIDRLLEFSAPLKEAYPFFHELVEAFRDKDPDLFFSLLAELPETLDDGFREKL
                     QNLLTYEEGITSAMIYPYSNGKIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLIN
                     VR"
     gene            complement(1364..1693)
                     /locus_tag="L1U99_002563"
     CDS             complement(1364..1693)
                     /locus_tag="L1U99_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBN1213077.1"
                     /translation="MNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSKYH
                     TKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQRL
                     EERMEEL"
     gene            complement(1683..1955)
                     /locus_tag="L1U99_002564"
     CDS             complement(1683..1955)
                     /locus_tag="L1U99_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBN1213078.1"
                     /translation="MEKMAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQ
                     GKIPFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            complement(2406..3209)
                     /locus_tag="L1U99_002565"
     CDS             complement(2406..3209)
                     /locus_tag="L1U99_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBN1213079.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            complement(3187..4311)
                     /locus_tag="L1U99_002566"
     CDS             complement(3187..4311)
                     /locus_tag="L1U99_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1213080.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            complement(4327..5142)
                     /locus_tag="L1U99_002567"
     CDS             complement(4327..5142)
                     /locus_tag="L1U99_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1213081.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            complement(5132..6004)
                     /locus_tag="L1U99_002568"
     CDS             complement(5132..6004)
                     /locus_tag="L1U99_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1213082.1"
                     /translation="MKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAPTKE
                     FVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNLYKP
                     LFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAGITA
                     WKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVMTIV
                     QGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAVFLG
                     VIFKFVEKGVYYEN"
     gene            complement(6089..7378)
                     /locus_tag="L1U99_002569"
     CDS             complement(6089..7378)
                     /locus_tag="L1U99_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1213083.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            complement(7606..8250)
                     /locus_tag="L1U99_002570"
                     /pseudo
     CDS             complement(7606..8250)
                     /locus_tag="L1U99_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
BASE COUNT         2713 a         1864 c         1395 g         2787 t
ORIGIN      
        1 ctctcgccta ctcctcgtgc ttgtagaagt tgtggttcta ctgtggtaga tggaaacggg
       61 aaagcaatta tagtgaaaaa tgggaagaag gaaacgattg tccgttttga acaatacaat
      121 catatgcctt tggttacgcg cctaaaaaag caacgctata cctgtaaaaa ctgtcgtacc
      181 cattggacgg ctcaaagtta ttttgtccga ctcagccatt caatcgcaga tcatgttcga
      241 tataaaattg cttctttact gactgaaaaa gtatctttgt cttttattgc gaaaagttgt
      301 caggtatctt tgactaccgt tactcgtaca ttgaaagagt ttaaaagcta tttaccaaag
      361 ccttctaaga agattctccc cagagtattg atggttgatg aatttcgttc gcacgcttcc
      421 atagaagata aaatgagctt tatttgcgca gatggtgaaa caggaaactt aattgctgtc
      481 ttgcctacgc gtaaattacc tcgattaaca agctatttct taggctgcac caatccagaa
      541 gaagtagaat tcttagtcac agacatgaac gccgcttact tccagcttac caaacgtgtt
      601 ctgccaaatg cgaaagtagt gattgatcgg tttcatattg tcaaacacat gaatcaggca
      661 ctcaatgagt tgcgtatccg tgaaatgaat gagcttcgta aagcaggaca gaaaagtcag
      721 gcagaaaaac tgaaaaagaa ctggcgcttt ctgctaaaaa atcgtgcaag catcaaccat
      781 tatgagtaca aaacatggaa aagtttccga gcaccaaaat acccatttct cactgaagca
      841 atgatgattg atcgattgct tgagttttct gcgcctctaa aggaggcgta tccctttttt
      901 catgaattag tcgaagcctt tcgagacaaa gaccctgact tatttttctc cttattggca
      961 gaacttcccg aaacgttaga tgacggcttt cgggagaagc ttcaaaacct tctgacctat
     1021 gaagaaggta tcaccagcgc aatgatctat ccttattcca atggaaaaat tgaagcgaag
     1081 aatacccaca taaagacaat gaaacgagta tcctacggat ttaaatcatt cgagaacatg
     1141 agaattagaa tctttttgat caatcaatta atcaatgtaa gataacaaaa aatctgaacc
     1201 agaatgtggt tcattctgac ccggatttga ttttgcacaa ctcatcagtc cttattgaca
     1261 aagagccaaa aatctgagcc agaatgaggt tcattctgac ccagatttga ttttgtacaa
     1321 cccatcagtc cttattgaca aagagccctt ctttttagta ttattataat tcttccatgc
     1381 gttcttccag tcgctgtaaa tcgcttggac ttaattcccc aatttttttc catttgacct
     1441 ttttgttgtt tttgggtaat tcgtttagag ttcctacgtc aatccaagat tcttttttta
     1501 gtcctgcctg tttccaatcc cttatttcaa cgtatttcag ctttatttta tcggatttag
     1561 tatgatattt tgaagtaatt gacagaaacg aaattgtgtc cagtccattt tttagaatat
     1621 agacaggccg gcgtttaccg ccctctgcag ctgtgaaagc aacgtagacg gttgctatat
     1681 cattagtatt catcttcatt gaaccattct tcaatttttt cgtcagtgtc tagtttttgg
     1741 acaggcaatt tttccgctaa tctttgaata ttatggattc gtttactttt ttccgacaat
     1801 tcaatagaaa atgggatttt tccttgctca acaatttgct tataaaaaac ggtgacggct
     1861 gttttggggc tcatgcctag ttcatcaata atgctttctg cttcattttt caatttttcg
     1921 tccatagaaa tttgtaactt agccattttc tccacctctt tctgacaaac acattatatc
     1981 acggaaagag ttcaaatgga attaatacaa ctacttttga actccttgaa atgcagtgta
     2041 tttatctaaa tataaggaaa ggatatagtg ctaaatggcc ttgatagata gaaaagtttc
     2101 aaaatccgcc acagcgataa ttgaagcgaa cactcaacga cacacagaac aggaaaagac
     2161 tcctaaaaga accaaattaa ctaggacgtg tctgaaaact ccacaaagat gtggtatgct
     2221 ctggtaaaaa acgaatggca caaccacgaa gaccgatatg gttcttggaa aactttctcc
     2281 accctttttg taattggagg gatagtggtt tattgatagc gattttccaa gttcttcaag
     2341 tggaaccaga cattgagcac cacggctaaa aagtgaatga agtctttatt tttaatcaat
     2401 aatttttaat gattaccagt aattggtttt ttcatgcgcc ctatttctat ttgatgtgga
     2461 gttaaataat gctgataagt aaaaattttt ccgtcaatta aactgccact agtgaatcct
     2521 gttctattgg taaaaagaga atagtctggg tattcatcta caccaaatga taaagattca
     2581 gccataaact gttttttacc agcaaattca gcactgctac cttgatggat atgtcctaca
     2641 aaaataccta aaatatcact ttcggcaatc aattcagcaa aaccttccgg aacttcagtt
     2701 acaatagatg gatcttccca cgacaatgga tgatgaacca ataaaatcgt tcccttttca
     2761 gcaggtgtac ccaaccactc ttgtaattga atcatctgtc ctatcgatat ttttccttcg
     2821 tgctgggtat cttgagcaga atccaaggaa ataattcgta acccattttg attcgtacaa
     2881 tggatatact ctcccgtttc attgctttca acactcattc cttcaaagaa aacactgcga
     2941 cgatcatgat tcccacgaca aaaatagtaa ggtgtggttg ggaaatattg atccaacatt
     3001 ttccgtaaga cttgataatc agaaatcccc ccttcatgta ctaaatcacc tgttaataga
     3061 ataaaatcgt acactgttaa cgagagttct tgtaacaatt tttccaatgc caactgtgga
     3121 tttttaattg ttggaaatag ttcagcagta aacaagttag tttgatagtt ttctctaaaa
     3181 tggatatcag agagatgcaa aaagcgcatg gctattccct ctttcttcaa taaaataatc
     3241 aggatatcct aaattttctt gcgtctgata atcaaaaaaa tgcattcttt caggttctat
     3301 gcggagattg actgcatcac caatctgcca agtaggtttt tcattaagga caatcatttc
     3361 tataccatcg actttaacgg tgtacgcata actttgacct aatagctcac gatacttcac
     3421 ttgaccgtgt aaatcgcttg tttcttttga aaaggttacg tgttctggtc ttatgcctaa
     3481 atacaatgag ccactaacct gaagaagttg tttttgccaa gctggattca atgttaaaaa
     3541 ttgactggct acctttaatg ttccttgatc ataagtaact ggcataatat tcatgcctgg
     3601 cgaaccaata aaatttgcag taaaagtatt tttaggtttc gtataaacat ttttcggcgt
     3661 atcaatcatc tgaattctac cttcattcaa taaaacaatc cggtcagcta acgtcatcgc
     3721 ttcaatttga tcatgagtga cgtagacaaa agtttgttta taacgttgat gaatttttac
     3781 caattctttt cgtgcatcca atcgtaaacg cacatccaaa tttgataacg gttcatctaa
     3841 taaaaaataa ttactccgtt taaccaccgc acgagccaat gctacacgct gccgttgccc
     3901 tcctgacaaa tctttaggaa gtcgatcttg gtatggcgtt aaacctaaca tcttcaaagc
     3961 ttcttccaaa cggtgctgaa tgtcagctgt cttaatttta ttcgccctta atgcaaaaat
     4021 aatattctcc tttacagtca tgtgaggata taaagcataa ttttgaaaaa ccattgcgat
     4081 ctctcgttct ccacaaggta gcttatttgc tagttgtgta cctaaaaaaa gctctccact
     4141 cgtaattttt tccaaaccag caatcattct cagcaaagta gattttcctg aaccagatgg
     4201 tcccagtaac acaattcgtt ctccagcggc cacagctaaa tcaatttctt ttaaaatggt
     4261 atgttctcca tatttttttc cgatatttct taattcaagc gtttctccca tgatttgtcc
     4321 tccaatttat ttaatacctg cagaaacaaa agtcccgata atatattttt gaaaaattgc
     4381 atacaagact aacggtacaa acattgtaat taaactaatc gccattgcta cggtaaaatt
     4441 tgtcccacct tcagaactaa tataggtctg catcgccaac ggcaaagtat aattatctac
     4501 tgtccgtaaa attaataccg gccaaacata ctcattccaa gaggtaataa aaaaccaaat
     4561 accggtagaa gtaatcgcat gtctagtaag aggaaaaaca attttactca tgacggttgt
     4621 ttgtttgatg ttatccaatg ccgccacatc tagaaggctc actggaattt cccgcattgt
     4681 ttgcgtcaat aaaaaaatgc ccatcgcatc agcaaattgt ggtattatca caccccaagt
     4741 agtatcaatt aaattaagtt ttgcaatcaa caaataatta ggaatcatcg caacagtaaa
     4801 aggaatgaac atcgtaccaa tgatgataaa gtaccagatt ttcttccctt tgattcggca
     4861 ataagtaaaa ctatatgccg caaaaaaagc tacgcctaac ttaacaaccg ttataattgt
     4921 agcaataaaa aaagtatttc tcgtaatttt gataattgga agattttcga acaaatagca
     4981 aaaattttcc aaggtaaacg gctgtggtat caaactagta atcgtctgat aggcatcttt
     5041 caatggctta aaagaattgg ccataataaa caataatgga tagataataa tgattatgat
     5101 gaacataaat aagagatgtg gcaaccagcg tttaattttc atagtaaacc cccttttcca
     5161 caaatttaaa tattacccct aagaaaacag caaatattaa taaagttaaa actgaaattg
     5221 ctgaagattc tccgacttta tacatttcaa aagccttttg ataagcataa tagatcacgt
     5281 ttgcactacc attattcggt ccaccacgag tgatgatctt aatcggagta aacacatact
     5341 gcagaccttg aacaatggtc atcaccaata aatatagtcc tgtcgaacta ctcataggca
     5401 acacaattgt aaaaaaaatg cgccagatgg gtacacgatc caacttagct gcttcgatca
     5461 tctcttgatc aattcccaca attgctgcaa aaatgacaat gaaattataa ccaaaaactt
     5521 tccaagcagt aatacctgca atcacagcaa ttacccaacc ttgtaaattc atccacatag
     5581 gcagtcttaa accaaaattt cccaacaaga cagcaattgg tcccgatacc ggatttaata
     5641 tccatgtaaa aaccatcccc gccactacca aagaaatcac agctggaata aaaaataatg
     5701 gtttatacaa attctgccct ttttctataa ctattcctaa taaaaaggat gtaatatatg
     5761 ggaacacaca gctcagcaag acaaatagaa cggtatagga caaagtattc ttcaacactt
     5821 tatgaaagac tggatcagtc agcaccttta catagttggc aaagccaaca aattctttag
     5881 tgggggccac catattccag tcaaaaaaac tcaaatagat cgtataaatc aatggataaa
     5941 aaacaaacac gcccaacaaa ataattgctg gcgccagata caaataacct acatagcgct
     6001 tcatttccga cagcctcctc atccttatgt caaaagcaga cgaccttgtt tttcctttct
     6061 tacaggcgct gtcgtctgct tgctttgctt atttgagtaa ctcattaatt tccttttgag
     6121 tagctttcat cgtttcattg acggaattac ctgataaaat tttatcccgc atatccaaca
     6181 atttttgttc agcttctaat ccagcatctc caggaaatga actccaactg accatcttat
     6241 ccatctgatc aattgctggt atcatcatct gattttcagc taagaaagct tttaatccat
     6301 tttgggcgtc tgcaacatct ttacgtggtg gtaaataacc agtaccttct gtccatttag
     6361 ctaaagattc aacactataa agatatttta agaaatccca agttgcttcc tttttcttat
     6421 ccgtttgtga tgtaacagct aacattgcgc caccagcagg tagtttaact tttttccctt
     6481 cccaacttgg tgactcaact gctttagcag taaaagtact atttttttga atgttgtccc
     6541 tttgagcaat agtggtatag accatcgcga cgttaccatc aataaagctt tgcacacctt
     6601 gttcccacgt agtgtgtaat gccgtctggt cttttaccat cctttgatat aattcataag
     6661 cagcgatacc atctttagaa gcaaaggtag ctttgccatc ttttattaca cttgccccat
     6721 tactttctaa aattgcttgt tgtgcccaat tatcagcagg ttcttgaata tacacgccat
     6781 actttccagt tttttctttt attatcttag aaaaagtttg aacttcttcc caagtttttg
     6841 gaccattttc atccaagccc gctgctttta atatatcttg atttaaatat aaaaccggat
     6901 tactaatgga gtaaggaata cccacttgtt taccatcttt ttcagacagt gccatgatat
     6961 tgtctaaaaa atgatcttta aaataatcag cattatccgg atccacttct tctactaaag
     7021 attgaggatt agtatatttg aaattttctg caaaataatc tttaaaagcc catcccactt
     7081 gtactacgtc cggtatttct ttggaggcaa cagaagcttg taaattttgc atcaagcctt
     7141 tatacatatc aggattatat tttgctacaa ccttcacttt gtcttgagat tgattgtatt
     7201 tatctactaa ttcattcact gtttttccac ctagggtatc cgcattaaca tgccaatact
     7261 ctatcgttac acgaccctcc gatttttttg ttgtcttggt attcccacta ccacaagctg
     7321 ccaaagagat gacacttaaa acagacacaa cccctataac aagatttttc tttaacataa
     7381 cattaacttc ctcctaattt ctttatggcc atttttctaa tcaagaaata ttatgaacta
     7441 ccaatgtaaa tttctagtta attttctgta aataattcga aatttgtgca tttcggggta
     7501 cagggtcact ggacatatcc atcaagctaa gaataaagcc cccatatggt catgtatccc
     7561 atctccaaat ctcttaactc ctctgttttg attataaaat agtttattct gtgctccttt
     7621 cttccataaa taggcccatg cacaacgtga ggttatatta taaacaccac agcgcgcaag
     7681 gtactcaatc gtttctagtt cattgactgt ccatacagaa aatgtcaatc ctagctgctg
     7741 ccccacttca cgggccaact tagttaacca tccttcatga atattgacga tttgaacgct
     7801 ttgataggct aatttctgta aggtatcgat caaatctgct tcggtaatat ccccaagttt
     7861 tttcccttcg aactgatttt caatattata aaatatatgc tttccccaaa tcgcagccca
     7921 agataattgt acatagccac taagaacaat ttgtggccag atttgatagg tttgtgccag
     7981 cgaaaaaacg gccatttcca atccctcttc ttttaaatca cagttaatgg tcatggttgc
     8041 cttctcattg gccactgctt gaaacacctg ctcaagggtt accgaatctg ggacaacttc
     8101 ttacctgtca tgggctagta ttagcgtacc atctgtttgc tgacgcacat ctacttcaaa
     8161 acaaagctgg cgatccaaac aaaagcgaag aaatgcccag ctattctcct ccgtattgtc
     8221 actaccagag tgtgcagtga tcatggtcat tttgacccct cctttaattc cgtgattttc
     8281 tcccacacgt ccactatacc gatgaagcgt taatttcttg ttaatttctt gtaaattccc
     8341 tgcgtttttt cagtaaacta gttgtaaatc ttgcatgctc cttcctacga actcatgaat
     8401 cgtcgatttt gcccttctag ctagtttcac caattaagta gttctacatt ccccgctttt
     8461 aacctactac accttttttt gttttcagct attccttctt cttgctgaaa gtccttgagg
     8521 ttctttctta caggatacca tcaaggtgtt caatggctta ttcccattga atgaccgaga
     8581 cttactatca gatttctgct cgttgaacca agtctttgat acaggatttc ttccgtcatc
     8641 ttctcacaaa taccaccttg cgtttctcta gcgattggtc gatgtgcacc ctcccagtgg
     8701 actgtcacta cccctttttg ctatgcctag cccacaaaaa aagctgtcct cacagacag
//
LOCUS       DAFLVO010000098         8547 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.100, whole genome shotgun sequence.
ACCESSION   DAFLVO010000098 DAFLVO010000000
VERSION     DAFLVO010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8547
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.100"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            476..1339
                     /locus_tag="L1U99_002571"
     CDS             476..1339
                     /locus_tag="L1U99_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBN1213084.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="L1U99_002572"
     CDS             complement(1468..3090)
                     /locus_tag="L1U99_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1213085.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="L1U99_002573"
     CDS             3339..3860
                     /locus_tag="L1U99_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBN1213086.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="L1U99_002574"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="L1U99_002574"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HBN1213087.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="L1U99_002575"
     CDS             5941..6759
                     /locus_tag="L1U99_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBN1213088.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="L1U99_002576"
     CDS             complement(6862..7059)
                     /locus_tag="L1U99_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213089.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="L1U99_002577"
     CDS             7228..7806
                     /locus_tag="L1U99_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBN1213090.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7901..8038
                     /locus_tag="L1U99_002578"
     CDS             7901..8038
                     /locus_tag="L1U99_002578"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213091.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
BASE COUNT         2599 a         1524 c         1672 g         2752 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacgt cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc
     8221 aaagaagggc gtatagattt cttttgatag gagatataca acagaaatga ataaatatta
     8281 acgtgttttc aaacagtata aaacggtgtg gtttttggaa taaaaaaata acatatctca
     8341 ttttacactt ttgttatttt atacttaaaa aataacgaca cagaaaatac cgtgtctcag
     8401 atttctctac tacttctaaa aactactgtt tttttccttt gaaatgcctt caaaaagtag
     8461 gatcaggcag aatatactgg cagaatcaag gagaagggag cctaaataag gagaaaaacc
     8521 atagaaaata taaagtaatt acttata
//
LOCUS       DAFLVO010000099         8494 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.101, whole genome shotgun sequence.
ACCESSION   DAFLVO010000099 DAFLVO010000000
VERSION     DAFLVO010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.101"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..173)
                     /locus_tag="L1U99_002579"
     CDS             complement(<1..173)
                     /locus_tag="L1U99_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006735101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1213092.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="L1U99_002580"
     CDS             complement(593..1714)
                     /locus_tag="L1U99_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HBN1213093.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /gene="istA"
                     /locus_tag="L1U99_002581"
     CDS             2042..3451
                     /gene="istA"
                     /locus_tag="L1U99_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HBN1213094.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /gene="istB"
                     /locus_tag="L1U99_002582"
     CDS             3448..4176
                     /gene="istB"
                     /locus_tag="L1U99_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HBN1213095.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="L1U99_002583"
     CDS             complement(4304..5215)
                     /locus_tag="L1U99_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBN1213096.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="L1U99_002584"
     CDS             complement(5232..6239)
                     /locus_tag="L1U99_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBN1213097.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="L1U99_002585"
     CDS             complement(6236..8365)
                     /locus_tag="L1U99_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBN1213098.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..>8494)
                     /locus_tag="L1U99_002586"
     CDS             complement(8370..>8494)
                     /locus_tag="L1U99_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1213099.1"
                     /translation="NGQCLMQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2599 a         1728 c         1486 g         2681 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg tttt
//
LOCUS       DAFLVO010000100         8066 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.102, whole genome shotgun sequence.
ACCESSION   DAFLVO010000100 DAFLVO010000000
VERSION     DAFLVO010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8066
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.102"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            302..1840
                     /locus_tag="L1U99_002587"
     CDS             302..1840
                     /locus_tag="L1U99_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HBN1213100.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            1837..2802
                     /locus_tag="L1U99_002588"
     CDS             1837..2802
                     /locus_tag="L1U99_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1213101.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            2789..4111
                     /locus_tag="L1U99_002589"
     CDS             2789..4111
                     /locus_tag="L1U99_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBN1213102.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      4174..4278
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            4352..5095
                     /locus_tag="L1U99_002590"
     CDS             4352..5095
                     /locus_tag="L1U99_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1213103.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            5110..6102
                     /locus_tag="L1U99_002591"
     CDS             5110..6102
                     /locus_tag="L1U99_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1213104.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            6114..6851
                     /locus_tag="L1U99_002592"
     CDS             6114..6851
                     /locus_tag="L1U99_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1213105.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            6841..7563
                     /locus_tag="L1U99_002593"
     CDS             6841..7563
                     /locus_tag="L1U99_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBN1213106.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(7647..>8066)
                     /locus_tag="L1U99_002594"
     CDS             complement(7647..>8066)
                     /locus_tag="L1U99_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HBN1213107.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         2576 a         1400 c         1756 g         2334 t
ORIGIN      
        1 ctcccccacg agatttctac tttattggct gtttcttttt attaaaataa aagttgtgtg
       61 tgtaaaaaag atatagctga ttccaagtga caatttcgta tagattttta tggtattcgt
      121 agtgaaaaaa cgagaaccaa aaagttgatc cgactttgtt gcttggattc tttttttgtc
      181 agcatattta gaggtatttt tttctttttt ttgttcgtgc tgtaaggtta aggcaagaca
      241 agttagttgg gaaaaaggaa agaaatgttt atacttaaag aataacagaa aggaaggtcg
      301 catgaataat tttatacaaa cattaagtga aagaaaaggc gagttgctgg aagctgcatt
      361 tcaacatctg tccatttctc tcatttcttt gctgattgca gcactgattg ctattccttt
      421 agcgatttgg gcagccaatc ataaaaaaat ggcagaagtc ttattgcaga tcacgggtgt
      481 gctccaaacg attccttcac ttgccttatt aggtttactt atcccatttg tagggatcgg
      541 aactgttcca gcattgattg cacttgttat ttacgctttg cttccgattt tccaaaacac
      601 gtatattggt ctagctgaaa ttgacccgtc tattgaagaa gcagcggtag catttggtat
      661 gtccagaatg agacgcttgc tgaaagtaga gcttcccatc gcattacctg tcattatctc
      721 aggtatccga actgccttag ttttaatcat cggtacggct actttggcag cattgatcgg
      781 agcaggtgga ttagggacat ttattttgtt aggtattgac cgaaatacac ctgttttgac
      841 attgattggt gcgatcagtt ctgccttgct tgcaattata ttcagcggac tgattcgctg
      901 gttgcagcat aagaaacctc gatattccat cattacttta gcagcagtgg tgtgtttatt
      961 tggcggcgtt tctttatatc agtctgcctt gtttaaaaat gaaaccatca cgattgctgg
     1021 aaaattagga gcggaacctg aaatcctgat ccaaatgtat aaagaattga ttgaagacaa
     1081 cacaaaaaca gaagttgaat taaaaccgaa ttttggcaag acgagttttt tgttcaatgc
     1141 actggatcaa ggtcaaatcg atatctatcc tgagttcaca ggtactgtcc tagaaagctt
     1201 ggtgaaggta cctgaagcaa tgaaaagtgc tgatttgaca aaagaaaaaa catatgacga
     1261 agcagaagaa ttattgaata agcaattcga tatgacatta ttaaaaccaa tggcttacca
     1321 aaatacgtat gccttggcag tcaagagatc ttttgcgaac gaacatcaac ttaaaaagat
     1381 ttccgatttg gcagctatct ctgatcagat caaagcggga ttcacactgg aatttattga
     1441 tcgttcagat ggatataaag gaatccaaga agcatatggc ttgaattttt caagtgtaca
     1501 aagcatggag ccaagtttgc gttaccaagc aatcaataat ggagatgtca atattgtgga
     1561 tgcctattcc acagatagcc agctcaagga gtacgatcta gtgactctag aagatgatcg
     1621 agggttattc ccagcttatc aaggcgcacc gctgatgaaa aaagattttg ctaaagaaca
     1681 tcctgaaatc gttaaagcac tgaataaatt aagcggaaaa ataacagagg atcaaatgat
     1741 tgatatgaat taccaagtca atgtcgaaaa gaaaaagccg acagaagtag cacgaatctt
     1801 cctgaaaaat gaaggattag taaaggagga agatcagtga ctaaattaat cgagttcaaa
     1861 catgtgcaaa aaaagtatga tggaaagtat gtcatcgatg acctaaatct ggcaatcaaa
     1921 aaaggagaaa tctttgtttt ggttggtcct tccggtagtg gaaaaacaac tactttgaaa
     1981 atgatcaatg gattatctaa accatcagca ggagacatct acttcaaagg aaaatcgtta
     2041 aatgaatata atctgcagaa aatgcggtgg aatatgggat atgtgctgca gcaaatcgct
     2101 ttgttcccga ccatgacagt caagcaaaat attgaagtca tccctgaaat gttaggttgg
     2161 gaaaagcaga aaagagcaga ccgtgtagat gaacttcttc aaaaagttgg cttatctcct
     2221 gatatttatc gagatcgtat gcctagagag ttgtctggag gagaacagca acggatcggg
     2281 atcatccgag ctattgctgc aagcccagat gtgattttga tggacgagcc atttagcgca
     2341 ttagatccga tttcaagaaa ctcattacaa gaattggttt tgtccttaca cgaagaattg
     2401 ggcacgacca tcgttttcgt tacgcacaat atggaagaag caatcaagct aggtgatcgt
     2461 attgcattta tgaaggatgg agaaattatc caatgtgaca caccagagca gttattgatg
     2521 aatcctaaaa acgactacgt tcggcatttc tttgatgaac cgaaacagac gaaagagtgg
     2581 cgagtagaag atttagtcgt caatggatat ttcttaaatg aaataccaga aaatgctcgt
     2641 caacaagttt gctttgatac gcctatgaaa gaagtatatt cgcttctttc ggtgtatcca
     2701 agcattgtga tagtagaaaa gcaaagaagt attgggtcgc tgacaagtaa agaaatcttt
     2761 gcttttttaa gtcgagagga ggaaggaaat gaaaacatat gatgcaatca tcatcggttc
     2821 aggtgtgagc ggcttaagtg ctgcttatgg attgaaagaa gcaggtaaaa cagtactagt
     2881 ggtcgaagaa gatctatggg gcgggacttg tcctaaccgt ggatgtgatc ctaaaaaagt
     2941 cttgttaagt gcagtagagg cacgtaatcg ggtaaaacaa ttgagtggaa aaggttttaa
     3001 cgagatccca actgccaact gggaagaact tcaaaaattc aaacgaacat ttacggatcc
     3061 agtcccagaa agccgaaaaa aacaattagc agaagctgaa atcgatcatc tttcaggaac
     3121 cgctcgtttt ttggatgatt catctattga agtcaacgaa gaagtcttcc atgcggatta
     3181 cttagttttg gcaaccgggc aaagacctac gatcttacca gtggagggaa aggaatactt
     3241 gaaaactagt gcagactttt tatcattgcc tgtactgcct aaagaaatca tttttatcgg
     3301 tggtggttat attgcttttg agctagctac gattgccaat gctgcaggga gcaaagtaac
     3361 cattgtccat cataatcaac ggccattaaa agaatttgag gcgtctttgg tagaggaagc
     3421 cgtccatcaa atggaagcat ctggcattca gtttgctttt ggtgttgaaa cccaaaagat
     3481 catttcagaa ggtactcgct atcgtttagt cggaaaagag acggaattag tagcagatat
     3541 gattttttgt gcgactggga gacagccgaa tacagaatct ttagcacttg agcaagcgaa
     3601 tatcgtcttt gataaacacg gaattgcagt caatgattat ctgcaaacga gcaatccaaa
     3661 aatttttgcg tgtggagata ttgtttcaag gaaaacccca aaattgacac cagtcgccac
     3721 ttttgaagga aattatgtag ctaagcggat aacggatgca acaagcgaac ctatcaaata
     3781 tccgattata cctacgatcg tctacgccag tcctaaactt gctgaagtag gagttacaaa
     3841 aagtcacgcc tcttcgtcag atcaagtggt agagatggat cttaccagtt ggttcaccta
     3901 tcatcgtgtc aatgaaccag ttgctaaggc tgaattgacc tttgaccagc aaaattattt
     3961 gattggtgct gcagtgatta gcgagcaagc agacgaattg atcgatgatt tgacactcgt
     4021 catcaatcaa aaattgacta aaaaagagtt ggatagctat atcatggggt atccgacatt
     4081 ggcaagtgat ctctcctatt tattgaaata atcagcatga taactaaagc gcttgttgct
     4141 ttttccttct tgtgctacac tttaaaaaat gaatacctgt ttctggggat gtcgtagacg
     4201 acatgagagt aagttgtgaa cttagaccca ttgaacctgt cagttaatac tggtgaaggg
     4261 agaaacatag cagacgcttg aagcgggtta ctatgtcgtg cccatttcaa gcgttttttg
     4321 ttattcatat tagaagaaag gaggtaacaa aatgaagaaa aatctttatc cagcagtcag
     4381 tatggcattc attttaatta tttggcagat tgttgtcata gtttggaaaa tacctgcctt
     4441 tattttaccc ggacctgctg ctgtattttc tgcattagcg gcagatgcac aagtattact
     4501 ttcccattct gtcacgacat taaatgaagc agtgcttggt ttggtaatag ctagcgttct
     4561 ttcttttatt actgccttgg caatggatta ttggaagttt ttagaaatgt ctttttatcc
     4621 gttactagtg atttcacaaa tgttgccaat catggtgtta gggccattac ttaccctatg
     4681 gtttggtttc ggtatgcttc caaaagtgat ccttgttgtc ttgataagct attttccgat
     4741 cgtagtttct ttttcggata cattgaggaa agtatcaaaa gagcaaatca tctttttgaa
     4801 aacgatgggg gcagatacag ggaagattta tcgaatatat aaaataccag cgggtttatc
     4861 cggcttcttt tccggtttaa aagtggctgc tacttattgt gtcagcggag cagtcgttgg
     4921 agaatggcta agcgctcaag caggcttagg gtattacatg atacgcgtaa aaaacagcta
     4981 ccagatcgat aaagtttttg ctgcgatcat ttgtgtcatt ctattgagtt tattgctgaa
     5041 tggcgcttgt tcattattga aaaaagggta ttatcgtatg ctttatattt tttaagagaa
     5101 ggggatcaaa tgaaaaaatt atggctttta ttaccgctac tgttgctttt atccgcttgt
     5161 ggcactgcaa aagaaacaag tagcaaacaa gaaataaagg atttgaaaaa agtgacactt
     5221 gttttggatt atgtaccgaa tactaatcat actggcatct acctagcaaa agaaaaaggc
     5281 tattataaag aggctggttt aaatgtccaa atcatcgaac caggagataa ttcgacaagt
     5341 attggtctag taggtgcgga caaagcacaa tttggtgtaa gttatcaaga agatgtcact
     5401 tatgctcacg cagatggaca gaatatacca gtcaaagcaa ttgctacagt gatcaaacat
     5461 aatacttctg gattcgccac cctatcagac agtaacatcc attcaccaaa agattttgaa
     5521 ggaaaaacat atgcaggttg gcaaagtcca agtgaagaag ctgtcttaaa agctgtgatg
     5581 gaaaaagacg gcggggactt ttcaaaactg acaatggtag gaagcaatgg agaagggcca
     5641 gaaagcttag gaaaatcctc agatatccaa tggtactttg aaggttggga tatgatcaaa
     5701 gcaaaagaag cgggtattga actaaactat atcccattga aagaattaga tgaacggtta
     5761 gattactata ctccggtaat tattacgaat gatcaactga tcaaaagtga tccagaattg
     5821 gtacagtctt ttatggatgc cacgaaaaaa ggctatcagg aagctattaa ggatccaaat
     5881 gacagtgcta aactgttgca aaaatatgca aaagaaaatg atcggacgtt tttagaagaa
     5941 tcacaagcat tcttgtcaaa aaattatacg gatgatcctg agaattgggg attgatggaa
     6001 gaaaaagttt ggcgcaatta tacagctttt atgcaggaaa acggattgat caagcaagat
     6061 gtaccttcgc aagaactatt cactaatcag tttataaaat aggagtgata gatatgtcaa
     6121 tccaaatcag ccacttgaat gtagtcattg aaaacctgaa aatattagaa gacatccatt
     6181 tcactatccc taaagatacc tttacatcga ttgtcgcgcc aagcggagcc ggtaagtcaa
     6241 cattgctgaa aactttaaca ggagtccagc ctatgacttc tggaacgatc aaagtagacg
     6301 atcaaaaagt aactggtctc catacagcat ttagttatat gccgcaagaa gatatgttac
     6361 ttccttggct gagcgtctat caaaacgtta cgttatatca aaaaatcaat catctaacaa
     6421 tcaatgaaga acaagtaagg gattatctgg atatctttgg gttaaacggc tatgaacatt
     6481 ttttgccgga acaattatct ggcgggatga agcagcgaac ggccttgtta cgaacaatca
     6541 tgaatccttc ttcttacttg cttcttgatg aaccatttgg agcgttagat gctatgacca
     6601 gagggcagat gcaagactgg atgttgaagc tgcctaaaaa agcaaagcgg actactttac
     6661 ttgtgacgca tgatatcgaa gaagcaattt atttatcaga caggattctt gtgctttccg
     6721 cccgtccggc acatgtgatt gctgagattc aagtgcctga aaaacgacgg tcacgtgaat
     6781 ggctactgca gcaatcagag ttgaagcaaa cgatttatca gttattggca ggtgaattag
     6841 atgttaagtg atgctcattg tcatttagat gggagtcaga gtttagcact ccttcagcag
     6901 gaacacacga ttttgacgat catcaattgt gattcgccag aagaatggaa ggaaaacaga
     6961 cagcttgcag caagtaagac tcaagcctta agttacggta tccatccttg gaaagcagat
     7021 agctatacgt ttgaacaagt tgagcctttt ttgaaaaaag caaggatcat cggtgaaata
     7081 gggttagata atatttggac gaatgtaccg atgactacac aaaaaaaagt atttgagcga
     7141 cagcttgctt ttgcagccat aaatgagaaa cctgttgtac tgcacacaaa aggatgcgaa
     7201 aaagagatct taaattatat ccaagcttac cctaatcact atttgatcca ttggtattct
     7261 tctttggact atcaacaaga ctatattgat ttaggctgtt atttcagcat tggtcttgat
     7321 ttgaaaaaga atccagcagt ctggcaacta gctaaagcag tcccaatcga ccacttactt
     7381 attgaaacgg atggactaca tgcagcagag tgggctttag gggggatttt ttcagaaaaa
     7441 gattatgtct cactgcttga agaacagtta aagacaatcg ctgagatcaa agagctatca
     7501 gttgaagaag ttaaaaaaaa tacttatcaa aacttggaac gtttcattag attaggtaaa
     7561 taaaaaagag atgtgacaca actagtgtcg cacctctttt tggctttctt tgtataaaag
     7621 taaactgttt gattaataaa tgaatcttag taccaaccgt ttgcttccca gaatgctttc
     7681 gccgcttccc aagaaccata acgtgaagta acatattgtt ctgctactct ttcttggttt
     7741 gcagcagagt agtcaccatt taagtaagaa gaatctaatt ggtaacgtcc gatgtaacgt
     7801 ccgttcgttg ctgtgtaaga accgcttgat tctttttgtg cgatccattc ttttgcagag
     7861 cttgtgcttg ctggagtagc agcagtttct gttacagcag gagcaggttg tgtttcagca
     7921 acaggcgctg cttgtttttc cgtttgaacc gtttcttgta caacaggttg ttcagcttgg
     7981 actggtgctt cttgaacggc tgcttgaggt tcagcagctg cttgtgcaga gccttctgtt
     8041 gggattgtta attgttgtcc tgagta
//
LOCUS       DAFLVO010000101         7972 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.103, whole genome shotgun sequence.
ACCESSION   DAFLVO010000101 DAFLVO010000000
VERSION     DAFLVO010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7972
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.103"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..313
                     /locus_tag="L1U99_002595"
     CDS             <1..313
                     /locus_tag="L1U99_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213108.1"
                     /translation="KKEMPIRCPNCNEVIKRKLSHGYFVSYELYEESKINLKKKPKYY
                     KNLKTGAIITEKEFKNLVTEEESRFYNLSGNICPGFMDQIIENESIESIENYVPVDLP
                     K"
     gene            complement(486..668)
                     /locus_tag="L1U99_002596"
                     /pseudo
     CDS             complement(486..668)
                     /locus_tag="L1U99_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            655..852
                     /locus_tag="L1U99_002597"
     CDS             655..852
                     /locus_tag="L1U99_002597"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213109.1"
                     /translation="MKDSIVEPEGMENTFELYNKTTVDKLIPILVPTDLNGHDVLLRF
                     NGFLGEDYRYLKISDPQPLTE"
     gene            complement(895..1470)
                     /locus_tag="L1U99_002598"
     CDS             complement(895..1470)
                     /locus_tag="L1U99_002598"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBN1213110.1"
                     /translation="MAQLFYRYGTMNSGKSIELLKVAHNYEEQGKRVIIMTSAIDTRS
                     GFGKVESRIGVSKPAIAITSEMDVYGELVEIIDQYGKVDCILVDESQFLSRENIIDLS
                     LIVMNEEVPVICYGLKNDFQNNLFKGSEALLTFADKIEEIKTICHFCNKKAVMNARIV
                     DGIPVYSGEQIVVGGNEDYLSVCRNHYYNED"
     gene            complement(1625..2151)
                     /locus_tag="L1U99_002599"
                     /pseudo
     CDS             complement(1625..2151)
                     /locus_tag="L1U99_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2608..4119
                     /gene="gadC"
                     /locus_tag="L1U99_002600"
     CDS             2608..4119
                     /gene="gadC"
                     /locus_tag="L1U99_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015082498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate:gamma-aminobutyrate antiporter"
                     /protein_id="HBN1213111.1"
                     /translation="MNKKKLSLFGFFALTASMVLTVYEYPTFATSQLHLVFFLLLGGI
                     LWFLPVALCAAEMATVEGWKDGGIFSWVSQTLGERFGFAAIFFQWFQITVGFITMIYF
                     ILGALSYVINFPELNTDPFIKFIGVLVIFWVLTFSQLGGTNRTAKIAKAGFVIGIVIP
                     SIILFGLAAAYFIGGNPIQMAINAKAFIPDFSQLSTLVVFVSFILAYMGVEASASHIN
                     ELENPQRNYPLAMFLLVILAIALDAIGGFSVAAVIPQHDLSLSAGVIQTFETLILHFN
                     SHLHWLVKVIALMIACGVMGEVSSWVVGPSRGMFAAAQRGLLPVFFRKTNKQDVPVPL
                     IMIQGIIVTIWAAVLTFGGGGNNLSFLVAISLTVVIYLVGYLLFFLGYFVLVFKKKDL
                     KRTYNVPGKTVGKTIIGGIGFILSVFALLISFVPPASIAASEHRTYQIILLISFVVTV
                     LLPFIIYEVHDKSAHTTIEEPTHVKAEDVNPAVYPAARGEHHVTKNDEHILKH"
     gene            4132..5532
                     /locus_tag="L1U99_002601"
     CDS             4132..5532
                     /locus_tag="L1U99_002601"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HBN1213112.1"
                     /translation="MLYGKDNQEEKNYLEPIFGSASEDVDLPKYKLNKESIEPRIAYQ
                     LVQDEMLDEGNARLNLATFCQTYMEPEAVKLMTQTLEKNAIDKSEYPRTTEIENRCVN
                     MIADLWHAPNNEKFMGTSTIGSSEACMLGGMAMKFAWRKRAEKLGLDIQAKKPNLVIS
                     SGYQVCWEKFCVYWDVELREVPMDEKHMSINLDTVMDYVDEYTIGIVGIMGITYTGRY
                     DDIKGLNDLVEAHNKQTDYKVYIHVDAASGGFYAPFTEPDLVWDFQLKNVISINSSGH
                     KYGLVYPGVGWVLWRDQQYLPEELVFKVSYLGGEMPTMAINFSHSAAQLIGQYYNFVR
                     YGFDGYRDIHQRTHDVAVYLAKEIEKTGIFEIINDGSELPVVCYKLKEDPNREWTLYD
                     LSDRLLMKGWQVPAYPLPKDLDQLIIQRLVVRADFGMNMAGDYVQDMNQAIEELNKAH
                     IVYHKKQDVKTYGFTH"
     gene            complement(5697..7132)
                     /locus_tag="L1U99_002602"
                     /pseudo
     CDS             complement(5697..7132)
                     /locus_tag="L1U99_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328084.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            7525..>7972
                     /locus_tag="L1U99_002603"
     CDS             7525..>7972
                     /locus_tag="L1U99_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HBN1213113.1"
                     /translation="MNKDITFPVMDVRLVPITKIQANDYNPNRVASPEMNLLELSIIE
                     DGFTQPLVCYYKEKEEKYILVDVLHRYRVAKERLNLKVVPVTVIDKPIEERMASTIRH
                     NRARGTHEIRGMEIVIQRLVKNGWSDKRISKELGMDIEEIFRFKQVS"
BASE COUNT         2541 a         1325 c         1435 g         2671 t
ORIGIN      
        1 aaaaaaagaa atgcctatac gttgtccaaa ttgcaatgaa gttattaagc gaaagttgtc
       61 tcatggttat tttgtcagct acgaactata tgaagaaagt aaaataaatc tgaaaaaaaa
      121 accaaaatac tataaaaatt tgaaaactgg agctattata actgaaaaag aatttaaaaa
      181 tttagtgact gaagaagaaa gcaggtttta taatttgtct ggtaatattt gccctggatt
      241 tatggatcag attattgaaa atgagtcaat tgaatcaatt gaaaactatg ttcctgttga
      301 cttaccaaaa tagaaaaaat aatcctgttt ttacagtgaa ttattttaat tttgattttc
      361 aataaaaata tattacaata ataatcgtaa tagctaatga aacaatttct caatcttttt
      421 accactccaa acagggagcg tcaataattt tgtgtaaata actcgtcctt ctgcaaaata
      481 atgggttact cagtaaacat tgaagctaat gtatccgtca cttgttggaa gcctttatgg
      541 cttctattta agaatttttg attgtatgta tcaaagatgg atactaggaa acgctctagt
      601 gattcttcat tttgaaactg ctcttttctg cggctgtatt tcttgatttg tttattgaaa
      661 gattcgattg tagaaccaga aggaatggag aacacttttg aactttacaa caaaactact
      721 gttgataaat taattccaat tttagttcca actgatttaa atggtcatga tgttttactt
      781 cgttttaacg gatttttagg tgaggattat agatacctaa aaatttctga tcctcaacct
      841 ttaacagaat aataaaaaac gtgtaatcaa ttatttgatt acacgttttt tatttcaatc
      901 ttcgttgtag tagtggttgc gacataccga aaggtaatct tcattacctc ctactacaat
      961 ctgttcacct gaataaactg gaataccatc aacaatacga gcattcatta cagccttttt
     1021 attgcaaaaa tggcaaatag ttttaatttc ctcaatttta tcagcaaatg tcaataatgc
     1081 ttcggatccc ttgaagagat tattttgaaa atcattcttc aatccatagc aaattactgg
     1141 tacttcctca ttcattacga taagtgatag atcaataata ttctctctac ttaaaaattg
     1201 agactcatcg accaaaatac aatcaacttt tccgtactga tcaataatct ccactaattc
     1261 tccgtacaca tccatttcag aagtaattgc aatagctggt ttcgaaacac ctatacgact
     1321 ctcaactttt ccaaatcctg atcgagtatc tattgcgctt gtcattatga taactctctt
     1381 cccttgttct tcataattat gagccacttt cagtagctca atactctttc cactattcat
     1441 tgttccatat ctgtaaaata attgtgccat taaatttatt cccttctttt acaattcaat
     1501 tattccttaa ttccatctgc ttttatgcag ctgctcgttt attccttgat atgtctataa
     1561 catctactat ccctaaaacc aatttataag ccattagaga tggtattcct gaacatctct
     1621 catattgttt tttgagtggt atatcatctg aaaaactgaa ggaatcatga aaatagcgac
     1681 atacttatca tttagagttc taactttaaa tgcatttact tcttcagtca gcactttagt
     1741 catgttggac atggtttggg gcgtgtagtg atgcccatac attttctcaa tcaagtctgc
     1801 gatttccgac atggtaatac cttttcggaa gaggtgaatg acggtctcct ctaatgtgtc
     1861 attcgtccgt ctataagcag gaacagtctg ttgcttgaac tcgccattgc ggtcgcgcgg
     1921 aatctggaga tgaagttccc catactcggt cttgaccgta cggtcatagg agccgttacg
     1981 agaattaccc gtgttaaaac caatgcgatc gtacttttcg taatcgagga aagccgttaa
     2041 ctccgttttg agaagcgtat tgacagcttt ttccaaatgg acacggaata atccattcaa
     2101 atcgcctttg ttcgctagag tctttaggat ttctgtagta aaatcgttca tatggaagtc
     2161 ctcttttctg tgaatgtgtt gtggtaactc tattctacag aagggacttc cttttttcta
     2221 tttacacaaa atattttaca ctctcaacaa aagtatcttc gattaatact tgctcaagtt
     2281 atgtgcagct acgaaaaagt aggtaccgag gtactttctt tttcgcagct ttttttggac
     2341 ttatgagaag tacattcgct ggaagaatac gatataaaac gagctttttc actaaagata
     2401 ttaatagagt gaaagaaaca agcttttgtt gtcagttttt tcacttttct aaaaatgaaa
     2461 ataaaaaatt ctggaagtgg agaagaattt tgcttgctat actttgtctt gtagaaaaga
     2521 ggtagacaaa ataatgcaag ctcaaataag cgattttcca taaccttggt aggaatgaca
     2581 aattaaatag gaaagggaag taataatatg aataaaaaaa agttatctct attcggtttt
     2641 tttgccctga cagcttccat ggttttgact gtttatgagt atccgacctt tgcaacatca
     2701 caattacatt tggttttctt tcttcttttg ggaggtattt tatggtttct accagttgct
     2761 ttatgtgctg cagaaatggc aacagttgaa ggatggaaag atggtgggat tttcagttgg
     2821 gttagtcaaa ctttaggaga acgttttggt tttgcagcta tttttttcca atggtttcaa
     2881 attacagtag gttttattac aatgatctac ttcatactag gagcgctgtc gtatgtaatt
     2941 aattttccag agcttaatac agatccattt atcaagttta ttggtgtatt agtcattttc
     3001 tgggtactga ctttttcaca gttgggcggg accaatcgta ccgctaaaat tgctaaagca
     3061 ggatttgtca ttggaattgt tattccttcg atcattctct ttggtttagc agcagcctac
     3121 tttatcggcg gtaatccgat tcaaatggct attaatgcga aagcttttat tcctgacttt
     3181 tctcagcttt caactttagt agtatttgta tcttttatat tggcttatat gggcgtagaa
     3241 gcttcagcat cacatattaa tgagctggaa aatccccaaa gaaactaccc attggcaatg
     3301 tttttactag tgattttggc catcgcctta gatgcaatcg gcggtttctc agtagcagcg
     3361 gttattccac aacatgactt gtctctcagt gctggtgtaa tccaaacatt tgaaacgctt
     3421 attttacatt ttaacagtca tttacattgg ttggtaaaag tgattgctct catgattgcc
     3481 tgtggcgtta tgggtgaagt tagttcttgg gtagttggtc catcacgagg gatgtttgca
     3541 gctgctcagc gaggtctgtt accagttttc ttccggaaaa ctaataaaca agacgttcca
     3601 gttccgttga ttatgataca aggaattatc gttactattt gggcagcagt cttaactttt
     3661 ggtggaggag gcaacaattt atcattctta gtagcaatct ccttaactgt tgtcatttat
     3721 ctcgtaggat atttactatt tttcctaggt tactttgtat tagtttttaa gaaaaaagac
     3781 ttaaaacgaa cttacaatgt accaggaaaa actgttggca aaacgattat cggtggaatt
     3841 ggttttattt tatcagtgtt cgcattgctt atctcttttg taccaccagc ttcaattgca
     3901 gctagtgagc accgaacata ccaaatcata ctacttatta gctttgtagt gactgttctt
     3961 ttacctttta tcatttatga agtacatgat aaaagtgctc acacaactat tgaggaacct
     4021 actcacgtga aagctgaaga cgttaatccc gctgtttatc cagctgctag aggagagcac
     4081 cacgttacaa aaaatgatga acatatttta aaacattagg aggaattcat tatgttatac
     4141 ggaaaagata atcaagaaga aaaaaactat ttggaaccaa tttttggctc tgcaagtgag
     4201 gatgttgact tgcctaaata taagttaaac aaagaatcca ttgaaccacg aattgcttat
     4261 caattagtac aagacgagat gttggatgaa ggaaatgcgc gattaaactt agctactttt
     4321 tgtcaaacgt atatggaacc tgaagcagtg aaattgatga cccaaacgtt agaaaaaaat
     4381 gcaattgata aatcagaata cccacgaaca acggaaattg aaaaccgctg tgtaaatatg
     4441 attgctgatt tatggcatgc tccaaataat gaaaaattca tgggaacttc aacgatcggc
     4501 tcttcagaag cctgcatgct gggtggtatg gccatgaaat ttgcttggcg taaacgtgct
     4561 gaaaaattag gtcttgatat tcaagcaaaa aaacctaacc tggtgatctc ttctggttac
     4621 caagtttgtt gggaaaaatt ctgtgtatat tgggatgtgg aactgagaga agtcccaatg
     4681 gatgaaaaac atatgtcaat taatctagat actgtcatgg attatgtgga tgagtacaca
     4741 attggtattg taggtattat gggtattact tacactggtc gttatgatga tatcaagggt
     4801 ctgaatgatt tagttgaagc tcacaataaa caaactgact ataaagtata cattcatgtt
     4861 gacgctgcat cgggtggctt ttatgcacca tttactgaac ctgatctagt ttgggatttt
     4921 caattgaaaa atgttatctc aattaattct tcaggtcaca aatatggttt ggtatatcca
     4981 ggtgtgggtt gggtcttatg gcgtgaccaa caatacttac cagaagaatt agtatttaaa
     5041 gttagttact taggtggaga aatgccaact atggctatca acttctctca tagtgcagca
     5101 caactaattg ggcaatacta caactttgta cgctatggct ttgatggtta tcgtgatatt
     5161 caccaaagaa ctcatgatgt tgctgtttat ttagccaaag agatcgaaaa aactggtatt
     5221 tttgaaatca ttaatgatgg atcagaattg ccagttgtgt gctataagct gaaagaagat
     5281 cccaatcgcg aatggacact atatgattta tctgatcgtc tgttaatgaa gggatggcaa
     5341 gtcccagcct acccattacc taaagacttg gatcaattaa ttattcaacg cttagttgtt
     5401 cgagcagact ttggaatgaa catggctggt gattatgtac aagatatgaa ccaagcaatt
     5461 gaagagttga ataaagctca tattgtttat cataaaaaac aggatgtgaa aacgtacggc
     5521 tttactcact aaaattcttc agagaaatat aaaagaagtt aattaactaa taaaaggagt
     5581 tgtgattacc acacagctcc ttaaatctat ttgaataaat atatgatatt catttgttac
     5641 actctcaatc ttagctgttg ttctattcat cattactctt attgtaagta gttcagtcaa
     5701 atttgcttgt tcaattgatc gataacagta tgaattgttt gaaaagtaat cggatatata
     5761 attgttttct cactacctaa gccttcttgg tataaagaac tatcgcaaag tataatccgc
     5821 tgagtacaaa agaaagtgtc gtctactatt tctctaagtt gtttacaaat gatattacta
     5881 atagaaaagt gttctcccaa aatgtcttct aactgttgtc gatagtataa atacctaaag
     5941 tctgacggag ctactatgaa cacttcaatt ggagatttcc gtttatgctc atttaaaaga
     6001 cttaaactaa tggttagttt acgaatagaa ttctcattcc aacgcagaaa taaattgttt
     6061 tgttttcgcc attgttcaag aatttcatga acttctaagt acaaagcgcg ttgctcttca
     6121 tttaacaagt aagtcttatc aggttgaaat atctgaatat cagcccaaag tgagcggata
     6181 aacgggagaa gtgctttatc aaaaagtatc tgattttctt cagatatatt cagagataag
     6241 ataagttttt gactgagctc aatcaccaaa gggttatctg ctacatggtt ttgataaaca
     6301 acgttcaagt ctttttgtaa caattcaaag ttatcgcata gataatttct agagttgaat
     6361 agaaagtaga tataaaggca ttcatcttcg tcatgacata aagagaaaga aagttgctct
     6421 aatcctttct gtattagctg aaacaaggga gtatgtcggg caactctttt ttcttcctga
     6481 ctaaaatata ttgggttagt cttagatctc tgcaaaccga tagcgatacc taataaaata
     6541 aattgttttt caactgtagg gtaacttctt gaaaaaaatg tttttctaca taatcaatca
     6601 attgttgacc gctttgaata attgatttat ttagctggat caactctgtc cgatttgtct
     6661 catagattat cgttagtaac aaacttcgat aatccttttc aggaatttca aaatggccat
     6721 cagcatttaa gtactgcatt tgtttaaaaa aattaatcaa ctcatttcgt aagttgtaaa
     6781 ctttgcttaa cgaaatgaag gtagtatcag ctatattact ccaattgtgt tcccctgata
     6841 aataatgtcc tagtacattg aaaaagtcag agcgctgata gatgagttga gtgagtgcca
     6901 acctcgaaaa cgaagagtcg aatgcgactg taaagctact tctagatttc tccactgaaa
     6961 taatttgctg atggagtatg tcggtaatgc attccaagtc gttagtgaca gtgagtgggc
     7021 aaacgttcaa ttgatctgct atttcgcgaa tctgaatggt ccctttttcg tgtaattgct
     7081 cacaaatgta aacttgacga aaaatacttt tctccagata ggtttccaac atagtactcc
     7141 tcctagtcat tttatacata actattataa ctctaccaat cggaatagtc ctgtaatata
     7201 ttgaatcaaa aatataaatt ataaaataat tagatggggt atttggttta agtatccctt
     7261 atatagtaat aaatttatag gtgtgattct cgaattaata cccgaaaatg tgagagaatt
     7321 tttatggatt ttttaggata caaattaatt atttttgctt ttatcctgat taccagtcca
     7381 gtactgtcgg tatcccattt tgcagcaaaa tcatgttgat aaagtgacaa gaagactgat
     7441 gagatatatt atccaaattg agaagataat taatcggatt cttgagtata ccctactttt
     7501 taagaaagta gggtatacaa gcgtatgaat aaagacataa ctttccctgt gatggacgtt
     7561 cggcttgttc caattaccaa aatacaggcg aacgattata atcccaatcg agtagcgtct
     7621 ccggaaatga acttattgga gctttctatc attgaagatg gctttactca accattagtt
     7681 tgttattaca aggaaaaaga agagaagtat atcttggttg atgtgcttca taggtatcgt
     7741 gttgctaagg aaagactcaa cttaaaagtt gtaccggtaa cagttattga taaacccata
     7801 gaagaacgta tggcttcaac aattcgacac aatcgtgcaa gagggaccca tgaaataaga
     7861 ggaatggaaa ttgtcatcca aagattagta aaaaatggat ggtcagacaa gagaatatcc
     7921 aaagaattag gcatggacat tgaagaaatt tttcgcttta agcaagtgtc tg
//
LOCUS       DAFLVO010000102         7815 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.104, whole genome shotgun sequence.
ACCESSION   DAFLVO010000102 DAFLVO010000000
VERSION     DAFLVO010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7815
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.104"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..372
                     /locus_tag="L1U99_002604"
     CDS             <1..372
                     /locus_tag="L1U99_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32"
                     /protein_id="HBN1213114.1"
                     /translation="TTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPN
                     YPWPQMFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMT
                     VTEGAIKVDKLDYSINYECGF"
     gene            395..769
                     /locus_tag="L1U99_002605"
     CDS             395..769
                     /locus_tag="L1U99_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1213115.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
     gene            1258..1452
                     /locus_tag="L1U99_002606"
     CDS             1258..1452
                     /locus_tag="L1U99_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213116.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
     gene            1442..1795
                     /gene="tnpB"
                     /locus_tag="L1U99_002607"
     CDS             1442..1795
                     /gene="tnpB"
                     /locus_tag="L1U99_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBN1213117.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            1897..3444
                     /locus_tag="L1U99_002608"
     CDS             1897..3444
                     /locus_tag="L1U99_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBN1213118.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            3596..4024
                     /locus_tag="L1U99_002609"
     CDS             3596..4024
                     /locus_tag="L1U99_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1213119.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFFI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
     gene            4011..4253
                     /locus_tag="L1U99_002610"
     CDS             4011..4253
                     /locus_tag="L1U99_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1213120.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(4553..4768)
                     /locus_tag="L1U99_002611"
     CDS             complement(4553..4768)
                     /locus_tag="L1U99_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213121.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            4875..5189
                     /locus_tag="L1U99_002612"
     CDS             4875..5189
                     /locus_tag="L1U99_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1213122.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            5293..6471
                     /locus_tag="L1U99_002613"
     CDS             5293..6471
                     /locus_tag="L1U99_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1213123.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            6874..7167
                     /locus_tag="L1U99_002614"
     CDS             6874..7167
                     /locus_tag="L1U99_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBN1213124.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
BASE COUNT         2656 a         1214 c         1532 g         2413 t
ORIGIN      
        1 acaactttga ctattacatc gttaacaaag gagtttgctt taaaattatt tgtagatagt
       61 gatactcaag aaggatacga atttcgtatt tcattgatta ataatcagct tactttcgga
      121 aaaactccga actatccttg gcctcaaatg tttgataagg ggctgcaacg accactattt
      181 ttggaaatag gcaaagaata tgaactaaag ttaattgttg atgatacgat agctgtttta
      241 tatattgata atgttgcttt aagtactaga atgtatgata aagtcggaac agcattaagt
      301 atgactgtta cggagggagc aatcaaggta gataaactag actattcaat aaattatgaa
      361 tgtggatttt aaaacaattg aagggatgat gtaagtgaaa ttaaatggtt tacaacatat
      421 tggaattcca acaaaagatt ttggagcttc aaaaatcttt tatgaatcct tagggtttag
      481 tctgattaat gaagaaatga atgtgggaag taaagtcggc tttttcgagt tgaatggaac
      541 gataatagaa atatgggaag ataaaactac tgagtgtaga ggagccattg atcatctagc
      601 attagatacg gatgacatag atgaggtatt caattcaatt caagatttag gatatgaatt
      661 attagataaa aatattatgg aattaccgtt ctgggaaaat ggaatccgtt actttaattt
      721 ctacggacca aatcatgaga ttatagagat aagccaaatg aagaaataaa tagataacga
      781 agtgctctaa gttggtatga acgaaaagta cttcattttt tggtatcagc atttcaatag
      841 tttaatgaga atttactatt tcaaattaat tcaaagtgac agtatttttt acttatttgg
      901 tttcaaattt tgtaatcctt cctatttatt ggaatacact ccacattttg tatacaagtc
      961 atatcatgtt ttagcaaagc tcttaccaag caaagttata atgatgtttt ccaaagtttg
     1021 atctttcgat ggaggctaac acatattttt tgcaggacag ccaaaattag atgtatagaa
     1081 tagagtctgt gaggcgtata gacagtttat tgtctgtatg ccttttttta ttttgaaaaa
     1141 tttttagtat ttttcgaaaa atgctcactc ctagagtaag cgccccatag aacagtacct
     1201 tactaacaaa tgcacctcaa gatatacttg agctatcaag aagtctggag gttttctatg
     1261 tataaattaa atgagattgt tcctgtccaa ttaggaaacg aaaagagtgc accagaaaaa
     1321 ggtaaacccg cggctgccaa gttagcgatg cgcatcaaaa gagagaatgg ttctgaagtt
     1381 ttgatctata acggtattaa caattatatt cttcaagcta ttttgaaaga actgttgtcc
     1441 aatgctttat gatttacttc aaaccaaaca tatttatatt gtgtgcggaa aaacagattt
     1501 gcgaaaagga attgatggtc ttgccagtct tattcaacaa gagtatcaac tcgagcttta
     1561 cgaagatgcc gtttttttat tttgcgggaa ccgtcaagac cgtttcaaac ttctctattg
     1621 ggacggtgat ggttttcttc tctgttataa gcggatagaa aacggcaagt taaaatggcc
     1681 tcggacgaaa gacgaagttc gaaccttaac gaaccaacag gttcgatggt tgttagaagg
     1741 attaagtatc gatcaacctc gagctatttt gccaggaaaa aaaggagttt tttaagctgg
     1801 ggggttaaca caaaaaatgt gttgaacccc tatttcttgt gcgtttcttg tggtattctg
     1861 taacaaaatc agttcgattc aaggtggtga aaaattttgg aaactacaga tacgttgctt
     1921 cagttgcttc aagaagccca taaaaccaat caagcacaac aacaaaccat tcagaatctt
     1981 acaactgaaa tccaactatt gaatgaaaag gtcaattatt taaccaacaa attatttgga
     2041 cgctctaaag agactctctt tgaggaaacg aatgggcaat tgaatctttt tagtgatgaa
     2101 gaaatttctg taagtgttcc agaagcagct gccaccatta ttccagtaaa aggacatcaa
     2161 cgagttgtag gaacgaaagc agacaaaatc aaacacttac ctataacaga gaaagaacat
     2221 ctccttcctt tggaagaaca attttgtgaa cattgcggtt cacagatgaa agatatcgga
     2281 cggacaaaag tacgagaaga aattcgtttc catcaggcta tgttggattg tctcacccat
     2341 tatcaacata cctattgttg taaaagctgc gaaaaagaag gactttcttc ttttaaaaaa
     2401 gcgatcgttc ctaaaccttt gatttctaat agcttaggtt ccaatagttt agtggcggaa
     2461 acgatccgga tgaaatttgg tcagaaagtt cctgcctatc ggcaagagaa ctattggaaa
     2521 caaacacatg ggttggatat ttcgagagat aatatcacca attggcatat taaagcagtg
     2581 caaaacgcgt tagacccttt aggagaacga ttaagagtct atcttaatca agaagagatt
     2641 ctacacgggg atgaaacaag ttatcgtgtg attgaaagtg ccaaaacaga tacctattac
     2701 tggcagtttt gtacaggaaa agacagtcag catcccatcg tttattatca ccacgacgaa
     2761 agtcgtgctg gagatgttcc gaaaactttt ctcaaggagt ttacagggta tttacactgt
     2821 gacggctata gcgggtataa tgccgtggaa agtgtacgac ttgtctattg tttcgcgcat
     2881 gttcggcgga aatttttcga agcaattcca aaaggaaaga aaaacacgga tattcccgca
     2941 gctcaagcag tcaaacaatt ggataaatgg tttgtcctag aaaagaaatg gaaagacttt
     3001 tctcctgaga agcgattaag ctgtcggcaa caagaactgc gtccattatt tattgctttt
     3061 tatgagtgga tggcaacgat agatcctgtt gcaaaatcca agttggatgc agccgttcaa
     3121 tatgcgtgta aactacgaag tggttttgaa cctatttttg aagatggtcg tttagaactc
     3181 acaaataatc gtgcggagcg aaatatcaaa gagctggtga taggacggaa aaattggttg
     3241 cattccacaa gtcttgaagg agcacgaact tcaggaatca ttctgagtgt atataaaaca
     3301 gcagaactta acggattgaa tcctgtaaag tatctagagt ttctatttga taagatacca
     3361 aatcttcccg tactttcagc agaaacttta gatcaactgt tgccttggaa caaggatgta
     3421 caacaacatt tttctcgtaa ctaaaaacgc caaacattcc cgattctatt ctataggtcg
     3481 ggttatttga cgtacaggta ctgttctatg gggcgcttac ctcctagatt gtagtaataa
     3541 tggaaaggga tagaagtaaa acgagttgaa tgaatttttt gagggggaga atattatggg
     3601 cgactcagag gaaacccaca ttcaacatac gtttgacagt ttttgtaaga aagtagtctg
     3661 caatgaggcg ttaaatattc aaaagaagta cgctagattt cgccaacggc aaatatcaat
     3721 ggaaatattg gaacaaaaag ggttaggtac agagttctat tatttggaac caaatttgaa
     3781 tagtagtggt acttttattg tccttggtat gaaaatcttt atttccaatg aggagttggc
     3841 aaatgcgatt gcagcattac ctagtcaaag acaagaaatc atttttatgt ccttcttcat
     3901 cggtcttaat gatcgtgaaa ttggcgatat tattgggaaa agtctcggca gtgtttggta
     3961 ccaacgacaa atggctttgg aagagctagg aaagtatttg ggtgtcaaat atgaagcaaa
     4021 ataaacgata tataccattc ataccactaa cgacaatcaa agccgcagct tctggtgatt
     4081 caattgccat gtccatcgtt ctgtcaaaat atcaaaatta tatttcacgg ttagccatga
     4141 aaccagttta tgaagaagaa aaaggaatgg ttatgtatgt agatgaatat atgcgtagac
     4201 aactggaaac aaaattgatt gagaagatac ttgaatttga tacaactcgt taaagtattt
     4261 tttccctttc cttttcattc tatggaagtt ttttatcggg tcaaaataaa ggatttccat
     4321 aggctgaaaa tagcctagcg ctctttgaca aatgaatagc aaatctatca gtacatgtag
     4381 attttgattc tctagttacg ccatgacaag gttagctttt aagcgacaaa ttttaatatg
     4441 agaatcgcga ctacgataat gatacttccg taaccaaatc ggcccgccat tactgggggg
     4501 aggtgagatt cctatgtgct ttggcaaaac agctgataga tcagaaaaac tactatttcc
     4561 atatttcgat tttggttggc atatttttca tgccaaattc tgtgatttta atagcatcgg
     4621 caagatttaa tttttcttca gctctctctc cacttttaag tttttttact gtactcaagt
     4681 tgattcctgt tccgaatgct attgcattag ccgtagattt ttcaagaatt tctttaatta
     4741 tttttatgtc tgcaattcct tgtttcatat taaaaattcc tcttttctag tccgttttga
     4801 tggagtactg gagtgttttt ttacaatttt aaggggtacc gtggtggtcg ttttgatttt
     4861 gagagagaag ggtgatggag ttggaagtta aaacaaatgt taattctctg gaaatagagt
     4921 tctattcaat tttacaaaaa aaactggaag attacacgga aaaattgctt gcagtcagtc
     4981 atttacctct ggtattaaca aatactgatt taaagcgact atttcagata agtgatagta
     5041 cactgaaccg tttagtaaaa cttggtgagt ttcctccctg ttggtacggg attcgaggac
     5101 actattttcg tgatgatgtt ttagaatgga tgagaaagag tgattcgaat gactatcgag
     5161 aaaaattgcg actacttcga tctttataag ttacattttc tttctaagat gcggtacaat
     5221 gatgacatag atagaaagat ttccaaaggg tttctgcttg ttgggttcct tcaaaatagg
     5281 aggaatcaat aaatggaaaa aacagatcga ttcaagaagc aaatcagttc tactggtagg
     5341 atcacatggt actttcaagc atatcgaaca acaagacgtg gctttaattc aaaacgtgag
     5401 gcgcaactcg cttatctgga aatggagaaa caacaaaggc ttaagaaaaa aattgttgca
     5461 agcaatgaca agtttagtgt tgtaggtgag caatggttcc aatattaccg ttcgttaaat
     5521 gaacaaaagg aaataaccta tgataagcga gaggaacaat taaaaattat tgttcgatgg
     5581 attggtgata aaaagttgtc tgatttgaca ccagagtgcc ttcaagaatt gctttttacc
     5641 ttaaaggaat gtggcgttaa tggaacaaat gttggctatg ccaaaaatag tttacaatca
     5701 cttattcaag ttctaaatat gatttttaaa tattgtcaaa gaaagaattt gataagtgaa
     5761 aatccaatga agtctgtgag aatgccaaaa tatcagttaa cggtaactga tttaaaagaa
     5821 gccataaata atattgagga caagtttctt actgtcgatg aattgagaac ttttttgaat
     5881 tatggcattg ttcatgagga attaccgatg tctgtacttt tccatgttct attttacact
     5941 ggctgccgag tcagcgaggc gcttgctcta cagcctggag atatagattt caaaagaaat
     6001 gaaattctgt tctataagca aacggcagtt aaaggtaaga gtaaggattt tcgaattgaa
     6061 actactaaga cagttagttc tgctagacga gttctagtaa ctcctctagt tatggaaaag
     6121 ctacaacagt tgattaaggc tttgggtgag atgaggcaac attacaggtt tattatagaa
     6181 gaaacatatt tgtttgtgta tcttgattct agtaaacgtg gtgttcctta tcgtcgagag
     6241 tatgtaaatg atcacgtcaa acggtgcgtg aatcgctcag gaattaataa gccatttcat
     6301 actcatttag ctcgtcatac aatggcaagc ttagtagcgg aacactgtag ctgggaagtc
     6361 ttgaaagatc gcttaggcca tactgaccaa acaacttcga aaatttatcg ccacttaacg
     6421 tcaaatgaaa aggtaaaacc tctgattgct tttagttctt tagagagtta aaaaaacggt
     6481 gaaagcactg gtattacagg attcttgaaa aacgattttt taacaaatta gtcaatatgt
     6541 agtcagaggt aataaaaatc cttttatatc aatactttaa cgacttttca caagtatcaa
     6601 agaaatccgt cgttaatcat tgttatcaga ctgagaaaga acccttggta ttcaagggtt
     6661 cttttttctt agcatgtaat ttgaacaccc tgatccagtt ttttctttaa ttattggtag
     6721 gggagaataa tggattagaa taaatctacc tataagtagt agtaaaaaaa agagcactat
     6781 gataatatct ttcttaagag taaccgcttt aataaaaaat ccagaatatt ctaacataaa
     6841 tggagtattc ttagaatcaa aaggagaaag aagatggttt atacttatac ggagcaagaa
     6901 aagatgaaag ttttagacac attcatgaat gatggaaaag taaaacaagt accaagttca
     6961 acaaaaaaga aatacatcct attgaaagaa gtcttgaaac gctttgacca tggagtgact
     7021 tatacagaaa cagaggttaa ttcgatactg ctgaacgtat tttctagtgg cgattatgtc
     7081 gaacaaagac gttatctaat cacatttggc tttttcaaaa gaagttcaga cggtcgggca
     7141 tatcagatga tgggaattga aaattagaag ttttaattta tactcattga aaaaagttca
     7201 agtatgcgat attggttcta caccgcatac ttgaactttt tttgtcatct gtatctataa
     7261 tacaaagcca agaacgttat tcaaaatatg gatagctatg ataaaagcta atgagcgatt
     7321 cgcagttaaa taagcaatcg tcagtaaaat cgttccagga gcgtacatga aaaaatcaat
     7381 tggatgcgtt acatgaataa agataattct cttttatttg tacgaataaa taccaaaacg
     7441 tacctcctaa aattagattt tggacagatg ccctttaaaa agataacaag atttcgttct
     7501 tgaaacaata tatatgcttt tattccaatg aggttgtgaa aacagtattt tgtcctgagc
     7561 gttagaaaat tgaaaatggg gaatagcaac tcgtacttta ccatttttta agtgaataca
     7621 agatcagcta attgaacacc gtttattcgt gatgagggac acaacactgc agtcgacaca
     7681 tttctctttt atgttcaaag ataacaaata tttaaaacaa agaaaaatag tagataatcc
     7741 cgtcctaact cttttattct tccctcatag cttccaaatt taagcaatac ttcaattaat
     7801 caagttttat ctttt
//
LOCUS       DAFLVO010000103         7812 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.105, whole genome shotgun sequence.
ACCESSION   DAFLVO010000103 DAFLVO010000000
VERSION     DAFLVO010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7812
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.105"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(32..1384)
                     /gene="celB"
                     /locus_tag="L1U99_002615"
     CDS             complement(32..1384)
                     /gene="celB"
                     /locus_tag="L1U99_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBN1213125.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNSSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(1384..1902)
                     /locus_tag="L1U99_002616"
     CDS             complement(1384..1902)
                     /locus_tag="L1U99_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213126.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(1918..2244)
                     /locus_tag="L1U99_002617"
     CDS             complement(1918..2244)
                     /locus_tag="L1U99_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HBN1213127.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(2257..4236)
                     /locus_tag="L1U99_002618"
     CDS             complement(2257..4236)
                     /locus_tag="L1U99_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBN1213128.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(4257..4571)
                     /locus_tag="L1U99_002619"
     CDS             complement(4257..4571)
                     /locus_tag="L1U99_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HBN1213129.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            4739..5032
                     /locus_tag="L1U99_002620"
     CDS             4739..5032
                     /locus_tag="L1U99_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBN1213130.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(5110..6222)
                     /locus_tag="L1U99_002621"
     CDS             complement(5110..6222)
                     /locus_tag="L1U99_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBN1213131.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            6609..6788
                     /locus_tag="L1U99_002622"
     CDS             6609..6788
                     /locus_tag="L1U99_002622"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213132.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            6982..7152
                     /locus_tag="L1U99_002623"
     CDS             6982..7152
                     /locus_tag="L1U99_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1213133.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(7576..>7812)
                     /locus_tag="L1U99_002624"
     CDS             complement(7576..>7812)
                     /locus_tag="L1U99_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBN1213134.1"
                     /translation="DATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKH
                     LPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
BASE COUNT         2495 a         1555 c         1262 g         2500 t
ORIGIN      
        1 ttttttgtca cagttccttt tttcttagaa atcattttaa cttttcacta gctaattctg
       61 ctgccttttc tctttcttca tttaataatt tattatcata gaatttgata aatgggaacc
      121 agataatgaa tgcgatgatt gcacaaatga ctgctaacac agcagctttc caatcaccac
      181 cactaccaac aaatgctccg atcccgactg gtgaaggcca cggcatctgt gcaagcatcg
      241 gtttgacgat ttccagccga atggcaaaat aagcgagtgt agcagaagcc atcggagcta
      301 agaaaaacgg aaccgctaaa tagggattgt agacgattgg catcccgaaa atgattggtt
      361 cattgatatt gaataatcct ggtacaagtg aggcttttcc taacactttc agctgatcag
      421 atttcgcgag gaatgcaata aagatgatca atcctaaagt cgcacctgat ccaccaacgg
      481 ttacataaga actgttgaat tctcctgcca acggataatt tgcgccttgt gcgttagctg
      541 ccatattagc taatacgatc ggggtcaaga aagaagtgat gatattcgct ccatggatcc
      601 ctacgatcca caatgcatgg atcaagaaat aaatcaccat gacaccaagc catgtattcg
      661 tcaactgcgt aacaaaccca aatgggatag caatcatttt gaagatatcc gttcctagtg
      721 caactaataa tccattgatg atcatcacca caaacgcaat gacaaatgtt gggatcagag
      781 cagtgaaaga acgagaaact cctggcggaa caacatctgg catttttatg acccaatttc
      841 tcttgacaca catacaatac aattcgaccg caataatcga cataataata gctgtaaaga
      901 ttcctgaagt tcctaaacgt tcgacaaaag agcccatcct aataccattt actacagttt
      961 ctgtctcatt gatagaagca atcaagctga ttttaccatc agtcatgatc aattcaggga
     1021 tacacataaa gaatgcaaaa acagatagta atgcccccgt gagcggatta acatttaatt
     1081 tttgttcatc tcgttcaatt gacgttaatt cataagcaaa cacaatggca aagtaaatag
     1141 ataaaatccc catcgtcatt gtattgacga tcatgtacaa gtcactaact ttgaaaaaag
     1201 ttgcattaaa aaatccttct aaaaatggga acggtaatgg caaaatattt aaaaccaaaa
     1261 acatcgagcc tacaatcgtg aaaggaatag aagccatccc cgctgccatg acagcccgaa
     1321 cgattttaag ttgcgcaatt ttccccatag gtcccatcag gtatttctgc aaaaaatcaa
     1381 acattagtta ttctcctttc ctaaatataa cgctttttca tattgtttaa tacggatata
     1441 ctgttggtct tggttgagtg aaattttctt taaacgatac tgtataaatg cactggcaaa
     1501 aataccgctt acaacaagaa tgaaaacaaa taactgtcct ccattgttat ttgccataaa
     1561 aggatacaag aatgtaaatc ctgaggtaaa caacactgga atcactaata aattaaagac
     1621 actctggaac aaaaaatacc actttgtcca tggaacgttc gtttggtgtt ttcgataaag
     1681 ctttacttgt tctcctactg caggcaaaat agctaaaatc agaatcatcg gtaaactact
     1741 tcctaaactt ttagctgata gaagcagaat catccattgc atgttcatga aaaagaaaaa
     1801 ggcagtcagg taacgtacga ttagataacg attgaaatac atgtttttca aactaagttg
     1861 ctttttttct aattcgattt tcctttttac tgtatcctgc acaatgatcc ttcctttcta
     1921 tttatttttt tgatacaaat aattcatttc ctgtgcaact tccaataatg tcatcgtcgt
     1981 catcagatga tcttgtgcat ggaccatgat aatttccatt tctatttttg tcccgctggc
     2041 atattctttc agaagttgag tttgtgactg atgcgcatga agaatctctt catttgcttg
     2101 tcgcaacttc tcttctactt cttcaaacat ctctttacgc atcgagcgaa atgcttcatg
     2161 tatcagtgtc cgtgcatttc cgctatggaa aatgatatca aaagaagtca cttgtagtgt
     2221 ttcactgttt attttttcag ccatctgttt tcctccttat tcgatcagtt tgataaattt
     2281 actgctgaaa ttctcaaaaa taggttcagc taagatttcc tgctgtactt ttagctggtc
     2341 aactaaccta acgattgctt tagtcacgac cgtaattcct tcattttcga cataagaagg
     2401 cgaaactaaa aaaacaaaat gaatttcttg atattgatcc cactgcatcc cagaaggaat
     2461 caatgcaacg gctacctttg tttcgattcc aactggaaca gcgggatgtg ggactgccac
     2521 tgtatcactg aatatgattt gtcccatatt ttcacgttgc tggatctgct ttcgcatttc
     2581 tcttatatat ccttcttctt catttatgct cagcttttgc agcaaatcat gaagaatttc
     2641 ttcctttttc ggttcgtacg tataagtctt gaaaaatttt tcagacaact gttcggtgta
     2701 aatctgcttt ttttgctgta gagaaaatgc tggtatcggt ctatctgagg aatgataggg
     2761 tatagattct ccaactacct ttcgtatttt acgaacatca tcttcattca aaaaaatact
     2821 gacatgtaaa actggaattt tgaaaaacat tgtcgaaaga tcaatagaag aaataatcag
     2881 gtcgattcct tttaaagttg tttcattgat ctcataatag ccttttacac ttaccactgt
     2941 aatattttta ccgaattcac tgactacgcg attctttaat agttgggcac tgccgtaacc
     3001 cgttgcacag ataatcaatg catgtagttt atgcgcagct ctttcttttt ccaatgccgc
     3061 catgagatgc aaagccaaat aggcccattc atcttcattg atggtatagt ttttcaaagc
     3121 cggcatgttg ctgaaatgcc tttttactgc gtcaaagact ttgggatttt ctttctttat
     3181 ctcctcagtc aatgggttct caatgcgaat acctcggctc aatcgaatca tcatcggtga
     3241 caaatgatcg agtagtccat tgaaaagctg gagatcctct actaatgaaa aatgaaattc
     3301 ctgagacaat cttttcagaa ctttcgctaa ttcctttgat agttcctgat cattttgatt
     3361 ttctttgtga ttcgacttag ccatgagatg taatgtcaaa taagcaattt cttcttcggg
     3421 aaacgataca cctgcgatta cctcaatacg ttgaacgatc cgctgcgcca cttgatactc
     3481 tactcgctta gaaacttctt gttcgatgcc taattccttg atttcaaacc cttctcggag
     3541 ccgtttgatc cccaaagcca agtgtaaagt cagattctgt atgataaaat ccgaaacttt
     3601 taacttagct tctcttgttt catcgagaat gataatgact agctcttcaa aactgatgtc
     3661 tgggaaaaaa cggctttgcc ctaaatattc tttcaatgaa tttccataat ggtttccaaa
     3721 aaaagtatcc atgataaaat gccgtcgatt tctttcttcc ccttcgatcc atgtcccttg
     3781 accatgctta gaaacgattt ttagtgaata tggaatcaat cgctccttga tttcttgcat
     3841 gtcctttgtc aaactggaac gactgatata aagctcttct gccaaatcat ccataaaaag
     3901 aatggcatct tccaaaagca attggttcaa tatatacttt tgtcgatctt cggactcata
     3961 aaatccttgc ggttctctag catatccagg tactatttct tgccgactca aaaacaagtc
     4021 aaatgtcagt ctttgtaaaa tatgcagttg gtagccataa cctggtttag caatgatctt
     4081 acctccgttt ttttctacta actctttgat ccgctgcaag taattacgga ttgtccgatc
     4141 agataataac aattcagaag ctaaacgttg actggtgaca tactccttct tgtgatcaat
     4201 caaatatctc aacagcaatt tttccttctg tttcattatc atccactcct attccatcat
     4261 atgttctctt cgatcacctc tgctaacttc tggatgcctg tagggattgg gacatacgct
     4321 tggaaaggga tactaacaac aggctttcca acagattctc ctaatttttt gaatttatcc
     4381 aaaaacatcg tcgtttgcgg gctgatcaga aataaatcaa aatcactatt cttaatcata
     4441 ttatcgcctt ctgtagctga aactgcatct acgagtacct cttctctttt ttgcttaaag
     4501 aaatccgttg tctttgaggc catcatcgag gatgacattc ctgccgcaca aataatcaat
     4561 gcttttttca taaatcaatc actcctttta tttttataaa ccaagcatat cttgtaagcg
     4621 ttttctattc aaaatatata tttccgtagc attgcggaaa aaatgtgtat catatcttga
     4681 ataataattt ctggcaccgt gatatactag tgatagaatt ttttcaggag gggatttagt
     4741 gagtatcaca gtgaatattt tgtatacaag tacaaatgga caagccagaa aatttgcaga
     4801 agaaatggtc gaaagaaaca ttgtcaaagc gattcgtgca gaagaaggaa acgagaaata
     4861 tgactattac tttccactag aagatccaga atctctttta ctgatcgacc gttggaaaga
     4921 tgaagaagca atcgaaaagc atcacaaatc cgaaatgatg gctcaaataa acgaactccg
     4981 taaaaagtat aaattaaaaa tgaaagtcga acgtttcact gatttaccgt aaaaagatac
     5041 acatggaatg atagcaattt atcatccatg tgtatcttca ctttttcctt attttttatt
     5101 cgatctcatc taatgattca aaccgtgttt ttctcttatt tttcggataa gtatttcagt
     5161 caccccaata tacatgattc ctaaacatac cccaaggata ttctcaaaaa tgcggatcgt
     5221 tactgctcct ggaaccccga ataaactggc agtgattgcc aaagcaccaa aagaattaaa
     5281 aactgtttta tatctatagg tagaacaaac acctaaagct agaccaccta atataccgac
     5341 ccagttaaaa ggaataaatt ggctgatacc aataaataaa acacatccaa tcaatgagcc
     5401 aatgattcgg tctactgctc gttctttgaa accaatcgac atcaatccat agctagatac
     5461 aatagaagaa aatgcaaacc ctgcccacat caatcgctga aaagggacat actctcctgc
     5521 aacgatcaaa agactaatgc caaatgcata gatgagcatc caaatttttt cctgcgaata
     5581 catgcctttc aaaaaaatct ctttaaacaa gcttttgtct ttgttctttt ctcgatgttt
     5641 tctgtaaagg agaactgaaa accaacaaaa aaacaaaaat aataagctac ttgtttgtgt
     5701 aaagaaattc ttgttcaacg aatctttagg taacgaataa acaataaaga gatatgaaaa
     5761 gccgtacaaa gaagcattcc ccattttggg atcactagcg gttgccatta atatgctgct
     5821 tagtaaaata aaatgaatca acatgcccat aactgaccat ttgatcagct ggacatacgg
     5881 tgctactaat agtgagaaca tgacgattgc taaacctatg atcgaatggg aaatcttata
     5941 accaaagtca acaaaacgaa tactcatcaa catacagaat aaaaccacag cgtatggttt
     6001 atgcttcgat tcaaataatg ttgtaattat aatgataaaa caaatggcaa acaatacgat
     6061 gaataatgat cgtaaaaaca atgaacaaat atacatgcac ttttcttttt tagaagctgc
     6121 ttctcgtatt ttttgtttta aaataaacgg atctagttgt agagactgat aaaaatccac
     6181 ctgttgtcgt cctttctttt tacttttatt ttttacagtc atctatgaca ggttgtaaat
     6241 actatggaac atcatatggc gttgtcattt tcttgtcaac tatttttcct attcatgttt
     6301 ttataaaaaa acatatcgtt ttcttgtatg attaaatcac cacaaaataa acaactgaga
     6361 gaacgatatg ctttatgaat ggttctatca aaaaaattct gagatcaata gacaaaaatt
     6421 tgatgattac agaggtctct tacgaaacct tacagaagaa aaaaacattg atcgttgctg
     6481 cagttctctt ccctgctcca tgtgtctgta gaaattgtgg ttctgctgtg gtagatggaa
     6541 ataggaaatt aatggtggtg aaaaacaaga agaaggaaac cattgtccac tttgaataat
     6601 ataatcatat gccaatggtt atacgcctaa aaaagcagcg ctatacctgt aaaaactgtc
     6661 gaagccattg gaacgctcaa agttatttta tccgtccaag gcactcgatt tcaaatcatg
     6721 tcagacataa aatcacttct ttactgactg aaaaagtgtc gttatttttt atttcgaaaa
     6781 gttgttaggt atctttgaca accgttattc gcacattgaa agagttgaga agctatttac
     6841 caaagtcttc caaaagaatt ctgtcttgag tgttgagggt tgtgaatttc gttctcacgt
     6901 ttccgttgag gataaactga gttttatttc cgcggatggc gagacagaaa aattaatcga
     6961 gaaaatttac ctacacaaaa aattcctcga ttaacaaact atttccttag ctgcactaat
     7021 cctaaagaaa tagaattctt agttacagac atgaacgcca cctactttca gctcaccaaa
     7081 catgttctac caaatgcgaa attggtgatt gatcgattac ttggtttttc cacgcctttc
     7141 aaggaggcgt aacctttatt cacgagttgg ttgaagcttt ccgagacaaa agacccgact
     7201 tgtttttctc cttattgaca aagagccatt aaaactagag aaaaaattac aactgatcgc
     7261 tgattatttg tagaaagaaa atcaaagtat tacccaataa acttgagtca ttaggcaaaa
     7321 aacactgcga aactcaagaa tgattttcgc agtgtttttg tatatttttt attaactagt
     7381 attactacaa aggtttattt ttcacttctc aacgcagcac aaaattgtct ttacttattt
     7441 actggttggg ttcaaccttc tctactccga tactaatatt tgtttgtata ccccttctaa
     7501 aatcggtagt ttccattcaa ttgatgggta ctagttgatt ttaaaaacta tgcttattca
     7561 attttttatt ttagctcata tatttcgttt ctttctaaat tttatactga tgaaaacaag
     7621 tagcacaccc aatattgaca atataaactg gctaatgatg gtttctccag tttttggaag
     7681 atgcttattt ccactgcttg ttggattgtt tcctcttata tctgagctat cagcaacttt
     7741 tctattctct tttgttaaaa agatcgccac ttcttgttct ttttcgatct tgaaagttac
     7801 tggtgtcgca tc
//
LOCUS       DAFLVO010000104         7716 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.106, whole genome shotgun sequence.
ACCESSION   DAFLVO010000104 DAFLVO010000000
VERSION     DAFLVO010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7716
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.106"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..107
                     /locus_tag="L1U99_002625"
     CDS             <1..107
                     /locus_tag="L1U99_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ZinT/AdcA family metal-binding protein"
                     /protein_id="HBN1213135.1"
                     /translation="NESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(176..904)
                     /locus_tag="L1U99_002626"
     CDS             complement(176..904)
                     /locus_tag="L1U99_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1213136.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(917..2197)
                     /locus_tag="L1U99_002627"
     CDS             complement(917..2197)
                     /locus_tag="L1U99_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBN1213137.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(2338..2940)
                     /locus_tag="L1U99_002628"
     CDS             complement(2338..2940)
                     /locus_tag="L1U99_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBN1213138.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            3185..3391
                     /locus_tag="L1U99_002629"
     CDS             3185..3391
                     /locus_tag="L1U99_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213139.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            3703..4422
                     /locus_tag="L1U99_002630"
     CDS             3703..4422
                     /locus_tag="L1U99_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBN1213140.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(4503..5186)
                     /locus_tag="L1U99_002631"
     CDS             complement(4503..5186)
                     /locus_tag="L1U99_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBN1213141.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            5405..7591
                     /locus_tag="L1U99_002632"
     CDS             5405..7591
                     /locus_tag="L1U99_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBN1213142.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT         2769 a         1300 c         1454 g         2193 t
ORIGIN      
        1 gaaatgaaag tcaagaagta ttgctgaaag aaatggagaa ttggccaaca ttttatccag
       61 atacaatgga tggacgtgaa attgcacagg aaatgctttt gcactgatag gcaaaaaaga
      121 accgaagggt ttggatcggc tggtcattta gtcggtccaa actattcggt tctttttatg
      181 aaatcaattt ctttaatcca cggatagagg ctgggatggt ctcgccgttt gccaacgtga
      241 cttctctggt ttttttatta atcgaccgca cattttgtgt attgataaca taggatttat
      301 gacaacggat aaaattccga tgcattttct cgatttcttt gatcttctca tagaattgta
      361 attgggcatg agtcaaatgg acttccagtt tatgtggcgc tcctagcgaa gtagaaaaat
      421 attggatgtc tttgatcggt aaaaatttga tctcatcatt aaactctatt ttgaagatat
      481 ctttttggat ttgggacatt tgaaaatctt cgaaaatttt gctcaggata tgctcgacat
      541 tttcttttaa atcataaaga tcttctttga cgatataatc agtcggttcg atgttgcttt
      601 ttaagatttt catcgacatt tccgtatggg aagtcacata gattattttt cctaaaggat
      661 ctaattcacg gatcaattta ccgatcgcta caccatccat ttcactgtct tctagttcga
      721 tatctaaaaa gtaaatacca aaagaagaag ttctgatctt ggctgcattg agaagttctt
      781 ccggatcaga ggtagaaata tggacataac tgtctaagtt ttcaatcatg attctatttt
      841 tgatcaccgt tgataaaact tctaattgtt ttggatcgtc ttcacaaata taaatgggaa
      901 tcatatcatt actcctttat tttatttgta tataaatcgt ttgagaaaaa cgctggtttt
      961 caattgatgt ttcaaggaaa agataaggat tggtctttgt caattcatcc aagataaaca
     1021 agccaaggcc ttcgtttttt ggatttgttt ttgttgagaa ccctttttgt ttcaactggt
     1081 ttaacggtaa tgtatttgtt gttgtattga tcacacgaat catcacggaa tgattcttct
     1141 tgagtatggt caattcgatt tttttcttct ttgcagcact agctccttca atcgcattgt
     1201 ccaagataat accaagcata cgtacaaggt ttaccgtatg tttcgtatcc agttcgattg
     1261 gctcaggaaa atgaagctgg acgatcaacc ctttttcctg tgccatcatg agttttaatg
     1321 acagtaaact acggatctca ggaactttca tattatccaa catacttaga ttggccggaa
     1381 aaaggttcat catctggcgt gtaggtaata tcgtttgatc ataataagac cgtaatcctt
     1441 ctaagtcgcc ttctgaaata tagctgtgaa gagaaaaaag cagattttgg taatcatgtt
     1501 tgaattctct caagtcttga tagttttttt ctagatcttt gatataatcc tgttgcatcc
     1561 tgacttgttg ctctaataac tgatcagcta atttcttatt agagattttc caataataaa
     1621 ccaagatgat caggccaaca cacagatata gaatgaaaaa actcgtattc aaagctaaga
     1681 catcaggtgt ttcaccagaa aaacgggtat aaaaaataat gatatagtat gtaaataata
     1741 tcaatgtccc gatcgtaccg atcatacggc ggtccacagt gtgaaaccaa gtctctaacg
     1801 atttttttaa acaaaaagct aataaagcag ataaaaaagc ggataagaca atgtgaaaat
     1861 actgcaatga atctcctggt tcaataaccg aagatttcaa aacaaaaaaa tcgccgatgc
     1921 ttgttaagtg atctcctaaa agcgacgtca ataacccaaa aggaagcgcg taaaccaatt
     1981 gttgacgcga agtcgaaaag aagaaaaaag taagcatcag cattcctata gcaattagag
     2041 cagtaaaaat ccctaaaatc gaatagaccc atccaatcaa aatacaagaa atcagaatga
     2101 ctcccgcaaa cagatatttg tatcggatgt gatggtcaat caataagata caaattgtgt
     2161 aaatcaaata ttgcaacgct atggaccata aaaacataaa gtacagctcc cattgatttt
     2221 taccaaatta tagcacaatt ggcgtattat ttttttaatt tttcagggat tttgaattca
     2281 gaactcatac caaagcagca gccagataca aaaaagtcag ataagttagt taattgttta
     2341 atgattgttt ttttcatgaa agattcctcc aaaattcatc aagtagtttg taataggaag
     2401 caacgtagct atttctaaaa caatcccaag tagcaaatag gtagaaaagt aagaagctga
     2461 gaaaaataac gtaatgagag aaaaaattag aaacatgctg atcgccttct ttaataatgg
     2521 gggacgtttc tcgggttcaa tgggattgat tgctgtacct cttgatccat agcgaagcag
     2581 taacaaaaag cagctgatta acaaaaagac catcattggg aaggagatag tcaattgcag
     2641 atgtttcatc accaagggaa cgccccataa ataaagtagt gtccacagca gacaaacgaa
     2701 ttcagagtcg gaatgcaatc cataagcata tctgcggatg cagatataag aaagaaaggt
     2761 gattcctgtt tccgcccatg agcctgtcac cagagaaaag actagaacga ccgctagttt
     2821 tccaagatta ttcaataaaa cttctaagac aaattttact tggacataca ccatatcttc
     2881 ttccgatttg tctccgctga ataaggcttc taataatttg ttcacaactt tatctttcat
     2941 ctcatacgta cctccaccac aaattttatg ctaaaaaaaa taaaaaacgt cttttgtttc
     3001 ataaaaagtg gttttgacat caaaaccgtc atgatctcct aaaaaaatct tcgttttcca
     3061 agaaccttac caaaaaaagt gacagttttg atacgaaaag tactttttat gacaagtttg
     3121 tgctttttcg agtgatttat gttaaaaaat tactgacctt ataaaaggtg atggagggat
     3181 tcttatggaa aatgaacaat tgtttgaagt cggcgaaaca tatgcattta aatctgattt
     3241 atttgaatca ccaataaaag gaaaaataga aaaaatctat gaaaatagtg tgatgatacg
     3301 tgtcatgaaa tgcgcagtag aagacaatga taccgctcat aatctgcact ggcagttagt
     3361 tgtacgcaaa tcaagtacaa tagaagaata aaaacagata aaatgttgag agcataaaga
     3421 ggttgtgagt ctcccgttta gctctgagtt acaaggaata atgttaaaaa acagcttttc
     3481 atgttttatg aatattgcct tgtgaccgag gtgttggcag gagaatactg tttatttgaa
     3541 aaaagggctg cgacaagact tttgtcacag cctttatttt catgaatagg agttactttt
     3601 ggctactttt agagaagtag cttttaagga gcagataaag tcaaggcttt tatttctata
     3661 aatgaagtag taaaatgaag aacagatttt attacaggaa ggatgccgat aattgtgatc
     3721 attgttgcag gaacgatcgg tgcagggaaa agcacactaa ctgaaatgct tgcccaagat
     3781 ttagaaacaa aaccttttta tgagaacgtg gaagataatg aagtattgcc gctattttat
     3841 tctaatccag aaaagtatac ttttttatta cagattttct ttttgaacaa acgctttttg
     3901 gcaatcaaag atgctttcag ccatgatgac aacgtactag accgctccat ctacgaagat
     3961 agtatgctgt ttcatttgaa tgcagattta gggcgtgttt ctgaagtaga agtaaagcag
     4021 tatgaaggtc ttttagaaac gatgctgaag gagttagaag aaatttcgcc acaaaagaaa
     4081 ccagatctac tggtttatat tcgtgtatcc tttgaaacta tgttagcgag aatcaaaaaa
     4141 agaggccggg aatatgaaca gctagaacaa gatcctgaac tctattccta ctataaagaa
     4201 ctcaatcgac gatacgaaga gtggtatgaa cagtttgata tatgtcccaa aatagtgatc
     4261 gatggggaca aatatgattt cgtagccgat ccggcatgtg gagaacaaat cgtacaagaa
     4321 atcaagatgc gggcaaagaa aatgacagaa gaggcagatg cccagtcgat ccgctacact
     4381 acaaataacc cgaaagcaaa gggaatcttt acaactaaat aatataaaaa ctaagcaaat
     4441 tgctcactcg cagatatttc tctgtgagca gcatcttgct tagttttttt gattcattga
     4501 gatcaaatag tgaaccgatt cgtatgataa aattgccata aatgaaatgt ctgagtgagg
     4561 gccatgatca aaaataaaat ggaaacgatc aaaatcgaat gggcgccaaa cagatgatga
     4621 cagaaaacaa ggacaatagc tcctgcgata aaggcaagaa cgacacttag atagtggaaa
     4681 aatcgatcaa aatctgcttt ttctttagaa atacaataat catataagtt cgttgctacc
     4741 ccttttaaat ttccagttgt aaataaatta gtgtaggcac gcccgttgat tttatcaaaa
     4801 gctacccact ggatcgatgc agtaaaagca atcaaaatcg ttactaatgc gggatgctca
     4861 tggacgggtg tcaaactaac aaagaaaaaa atcactgctt cataatatag aacaaacaag
     4921 cgccagaaat gtttttcttt ttttctaaaa taatcaatta gatactttgt tagaagaatc
     4981 cctaagaaaa agaaaagggt agacaatact tttttaccaa cacttagcca ttctccgtca
     5041 aatgcttgga tgatcgatag aatgatattg ccagtttgag cagaggcaaa agcaccatat
     5101 tggatataag tataactgtc catggctcct ccgataaatg tcagcaaaag tcctattgta
     5161 cgcccctcgt gaaaggaagt ctgcattttt ttcatcacct tttatgaata tttttgtctt
     5221 ccttatctta gcataaacga ttgaaaaaaa aggaaaaatt ttcagaaaac taaaatcata
     5281 tcgcttccca ttttcatttt tagaaaggtc tgttagtata aagaaaaaat agacaacgaa
     5341 actttaaata accaacttga aataaacaaa ttcaaagaag aaagatggga aggaaatcaa
     5401 tcagttgaat gaaaaagaaa ttctccgatt acaaaaagaa ttgaaacgct gggagaacaa
     5461 gtataaaaag cttcaacaag tctttcggct acaagaagaa atcattgcta cctatgaagc
     5521 ggcttatggc gaagcacccg gacttattga ggaagaagta caagtaaaag aaagtgaagg
     5581 aaacagctct ttctttaaaa tgatggagaa acgttcctat aatcgcttca atcaagaaca
     5641 aaaagcagct atcacatatg atatgaagaa acatcttcga atcatagcag gagctgggag
     5701 cggcaaaacg caaacaatct gtgcaaaagc tgtttatctg atgacgcaaa aacaagtaga
     5761 cgaagaacgc atactaatga tcacttttac aaggaacgct gcaaatgaac taaaaaaacg
     5821 agtagataat ttcagccaga gaaaaaccgc tgtccatatc ggaacattcc atagtatctt
     5881 ttttaggata tacaatgaaa tttgtcgaaa atttcctgaa gtagcaatgc aaggaataca
     5941 aggagacttt tcaaaggata ctgcacaaaa agtgaatgct gttttgcaac agctgatacg
     6001 taaatataat ctttatatat ttgatcaata tggagaaaaa acgattgctt ctcggttaga
     6061 ctattggcag aatatgaacc tttcagtaga agaaatggtt cagttagtta aagaaaaata
     6121 tgattccatt gataagaatg cacgacagcc gatatcagaa cgactgtatg gattgctcac
     6181 ggaactccaa gaacaaaaaa gaagccagca attgctagag ttcaatgatg tactccaaaa
     6241 tctgaaaagc gctttggaga atgaggagat ccagcattat atcggccaaa aatatgatta
     6301 tctattcatt gatgaatttc aagatactaa tccacttcaa tgggaaatcg tgaaacggat
     6361 gacaaaggaa aacaggatca agttgattgt tgttggagat gatgatcaga gtatctatgg
     6421 attcagagga tcagagccag catacatcaa gaactttgaa aaagaatatc ctaccaaaac
     6481 tcttttctta ttaactaatt atcgttctcg ggcagctatt gtccaaggag caaatagatt
     6541 gatcagctat aataaaaatg atcggatacc aaaggcgatg attccagcac aaaaagaagc
     6601 aggtgttatg gaagcctatt tgttttctga tactaaagca gaaagtcagt ggctaatcaa
     6661 acaaattcag acatttattc aaaaaaatgg gaaatataag gaatcaatca tattataccg
     6721 atcagcttca caaacgcagc agcttgtcca atctctgctg aaaacgaata ttccttttgt
     6781 actggaagca gatagtccat atgaaggtat ctttggtatc aagtctttcc aacatttcta
     6841 tcaaaaaatt gttcattggc aaacagcact gaatctgcaa aagaaaaatc aggcctacca
     6901 gcaattgctc cggcagctga tggcagactg ctacctgaaa aaaagtgaat gcgatcaata
     6961 cttttctcct aaatatcaaa atatagccgt tgcagattat attttgtcga taagccccaa
     7021 tttaaaatcg aaatctgcag aaatccgaga gtttgaggaa gcgttgcgta aaacagacca
     7081 gcatcaagaa atctattcgc ttgttcaaag ctatcttcat ctgccacgta tagctaagga
     7141 aatcgaccag agtgatcaag aatggatacg agaagaagta aagcagcatg ctactttcag
     7201 aagactccaa gccttatcgc aagaaaccca agcgacagct aaagaattaa aaacccgctt
     7261 gattgcttac agacaaggaa aacttgatgc actatgtatc cagagcattc acaaaagtaa
     7321 aggtcttagt taccgaaatg tctttttgat tggttgtaac gaaggaagtt tgccttataa
     7381 cggagcgaca gaaaagaaag taatcgactt taatgaaata aaagcagaac cagtaacgac
     7441 gatagaagaa gaacgaagac tattttatgt tgcgatgact agagcaagaa atcgtctgta
     7501 tctatgtgta cctcaaatga aaaattcaag aaaattgaaa gtatcgagat ttatcaaaga
     7561 aaccgggagt cgtgtgaaaa aaggaaagtg atagaagaga gggtgtgaca gaagtggtca
     7621 gtttcaagaa agaagaagga atgtacgaaa attgcttctc aaatttttgt gaaatttcag
     7681 cttattttcg aagaagctat ttctggaaca cagttt
//
LOCUS       DAFLVO010000105         7650 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.107, whole genome shotgun sequence.
ACCESSION   DAFLVO010000105 DAFLVO010000000
VERSION     DAFLVO010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7650
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.107"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            279..734
                     /locus_tag="L1U99_002633"
     CDS             279..734
                     /locus_tag="L1U99_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213143.1"
                     /translation="MNAINWHEFVNYMESLLDDLKSFSIADAVKHGLPVSTTMKLRGL
                     KIPDEIIKLRTKTIIETAKVVDNMNHELKGKKTTYEKDFERFLKSVIGKYLGKKSFSE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIIDYLENKEQKKGTKKGR"
     gene            853..1911
                     /locus_tag="L1U99_002634"
     CDS             853..1911
                     /locus_tag="L1U99_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HBN1213144.1"
                     /translation="MEKNVNSTSTKDQYSIIGGLLGDKDKRTRHGLRIMLATFLGVLF
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLEFARSGAEITISDVWTDQNRDVTVVKLG
                     YSQNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLDERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNEADSVTKALSQYSMNDVNNEGVISFGKKAKPVN
                     TPDNINFRINPYSDSTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVSKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKAINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            1953..3902
                     /locus_tag="L1U99_002635"
     CDS             1953..3902
                     /locus_tag="L1U99_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBN1213145.1"
                     /translation="MENSTEFFKNIQTEFNHALTPMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAERQRQDGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TLIPRLKEYERILKSEDKENEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQL
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPQASFK
                     LSQRIPDELLQEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDMEKLQEELKSIKGQPLAVYTITMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRRLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVHDTVSLSNTILFATTNAGAE
                     MFDSLNRYSSLSRVTNKENSNEYSTELKREYRKVASGIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAYNEMLKSAELVRKHLNIDLRLPPRKERVYGQNFYADDLSMHLV
                     FDMASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSEAGAFEGKGDS
                     NAEIIAKPSVAESKENKIVFSIGGA"
     gene            3905..7546
                     /locus_tag="L1U99_002636"
     CDS             3905..7546
                     /locus_tag="L1U99_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213146.1"
                     /translation="MKFKKYLLQNLRIKRWVVRGLVIGGVLAVTLGAPFGMNDPTPDN
                     QDSKQETVINKNVAYAESKPAEQGMWTLYARILMGDKEVNDSAAKTGQMNLLGQGGIS
                     ADFPYSDISKQGNSIAGGNAGTQLASTLATYSYYGYIETVSGNAIASQASSILGSIGR
                     TIGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGEGGSDVSNPVSKALTSLL
                     NNLGLNNELFKAIASLSMLFFTAILGYQGMKLLSKDGVNSKGLSPVLEKWIVRIFVLF
                     IFLPVAGSLLGVYINGIQSAKKDGDIPTNVVSDYIINTRLWASTQNLAPSSDTGGDVP
                     DGKPTSEIKFVDTDYEPSKKSAMIRAINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NINTYAGDVNVAENDAYMGRAPAVWTGYNLGDGKEGSAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTAHNFDATQPWGVANNATFSTQSVALLLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFIRIWEVVLTGSLASGAGVMAISLGVVTTSLIGLQLPIFLITFIRAFGDTAV
                     GFIPNTLVGDGVANIVRSAMILGVGYLLVFKKGEKVNNLINMLIGLPLEVAFGFDERA
                     KLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGNSSVKDMVAGGLGAVGAQKMAER
                     LNNMGDSNADAKSIADKVIPETPEGMSFNGGGVGSTINNTSFKDLVRQDQLRNNSQQY
                     IDHLGRMVDENGNFVDENGEILKDSKYGKDAKGNFIDEKGRLVDEDGNLIDTNGKPLE
                     DSEDGNIGMDSEGRLIDEKGRLVDEDGNLVDENGRRLLNGDFGHDSNGRLVDEKGRLV
                     DEDGNLVDEFGNKLGKHSDGYNVNGDLVDEDGNIIETRDALVADRNRELEQQRHTPIA
                     VAIPENEEDEITLDQTHQELRNEMSGEDVSDRVHRELGDGASGESQSRELNSNFDNSA
                     IRNDTVLKDRESLTKETDKEQSDVKKKFIPTPNVNQTDKYETNIGSGMSKDNQSIREP
                     ELTNKNNRTNNSKSTSDNSGKSNQSTKKTSTAKSAVEYLSKTGKNVYTSADKALAKAP
                     KGSLAGITYEAKNEAIKIGKGTAKVAKATATGASKTGKVVKKSTMSVKDYIVKYGNQK
                     STENKSEDE"
BASE COUNT         2729 a         1133 c         1603 g         2185 t
ORIGIN      
        1 acatttttgg acaagtcaac tatttgttaa aagttaatat agagtaatta gataagtttt
       61 ttcttttcgt ctgataaatg gataatatta gttattttat tgctaattag tctttcatga
      121 tgactgaaat agctaaaata aatatctcgt tggataattg ctgatacttt aagggatatc
      181 taaatttgct gattgattta tttatgttat tatgatatta taataacata aatgtgttac
      241 gcccgaacct cattttaaaa aaatgaaggg gtgagacaat gaatgctatt aattggcatg
      301 aatttgttaa ctatatggag agcttactag atgatctaaa aagttttagt attgctgatg
      361 cagtaaagca tgggttacca gttagtacaa cgatgaaatt acgaggattg aaaattccag
      421 atgaaattat taagctgaga actaaaacaa ttattgaaac cgcaaaagtc gttgacaata
      481 tgaaccatga actaaaaggc aagaaaacaa cttacgagaa agattttgaa cgttttttaa
      541 aatctgttat tggaaaatat ctaggtaaaa aatctttcag tgaattgaga gatgaagaga
      601 ttgtacctac tccaatggtt agcaaaatcc gaaaaaacaa agccgagggg aattactatc
      661 ttggtacaat agcaaaaatc attgattatt tggaaaataa agagcaaaag aaaggaacga
      721 agaaaggaag ataatttttg tgttaaatat taatggggaa gaatataccg aaatgattca
      781 aaatcccgaa cctagaatta ccgaaaaaac gtctgattgt ttgctctttt atgaaagggg
      841 gcagacaaac taatggaaaa aaacgtcaat tcaacatcta ccaaagatca atacagtatt
      901 attggagggt tgcttggtga taaggataag agaacacgtc acggattacg cattatgctt
      961 gcaacttttc taggagtgct ttttttatta acaggcttgg gtagctacat ttatcaatta
     1021 ggaaactata attattatct cgtgaacaat acaacaccta taggctcttc attggagttt
     1081 gctcgatcag gagcagagat cactatttca gatgtgtgga cagatcaaaa cagagatgta
     1141 acagtagtaa aactcggtta ctcgcaaaac gctagaaagt tgttatctac gcaaggaaaa
     1201 aactacaact tatatatggc aacgaaagaa aaagatcgtc ctaaaaagct tgaaatgagc
     1261 tatgggatgt taagtactga tggggatgct ttcttattcc taaaaggtaa attagatgaa
     1321 agagcttatc aagtttttat tgcaaaccaa gtatcactaa tttctggtga tgatacagct
     1381 gacgatgata ccaaagtcaa tgtgaatgaa gcagattcag ttacaaaagc actttctcaa
     1441 tattctatga atgatgttaa taatgaagga gtaatttctt ttgggaaaaa agcaaaacct
     1501 gttaatactc ctgataatat caatttcaga ataaatccat attcagattc aactaatgtc
     1561 tatcaaggaa gctttcttac caaagatggc gatattgatt attcaaaagt tgtagcagtt
     1621 acaagtaaga ataatgttgt aagtaagtta gaagatcagt taaatgcttc aaatactaac
     1681 atcaagaaaa ttgaagctac aaaagctgag tatctggaac gtttacaaca aaatcctgac
     1741 gataaagatt cgcaagaaag tattcgtcaa ctagacagtc gaatggagac cgaaattaaa
     1801 gcaatcaatg atacacaaaa attgattgat caatacaaaa atgctgactt taacaaagat
     1861 tcttttggag acatgaagac gacatttaag tacctaactc tgactgacta gaagtaaatt
     1921 attcttattt tagaggaagt gaacacaaac agatggaaaa tagtaccgag ttttttaaga
     1981 atattcaaac tgaatttaat catgctctca caccaatgaa accaccgaaa cataagttag
     2041 tgggacgtga tgacgaactc catgagttgt cactgatctt gaatagaccg gaaacaccgc
     2101 aagctatctt gttaggtgaa gccggaacag gtaaaacagc acttgcaagt gaatgggctg
     2161 aaagacagcg acaagatgga aagaaagtac aagtatacaa attatcaatc ggacaattgc
     2221 gtgttggggg agatgatgtc ctccaaacac gtttagaaac attaattcca agattgaaag
     2281 aatatgagcg aattttaaaa tctgaggaca aagaaaatga atttgtcctc ttcattgacg
     2341 agtttcataa agttgttagc tcttttggta gtggcaataa aattgggggt gattcgctaa
     2401 aagaaccgtt agcaaatgaa tcacttcaat tgattaccgc tactacaaga aaagaatatg
     2461 aaaactatat caaaagagat gatgccttag ggagacggtt acaaccgtta gaattgaatg
     2521 aactaaaaag cgatgttgtc gtcgatattt tgagacaatg gctaaataca tcctctgtta
     2581 aagatgatcc tcaggcttct tttaaattat cgcaaaggat tcctgatgaa ttacttcaag
     2641 aaatcgtaca agcaaacaag ctttatcgtg aggatttgtc cgaaccggct aaatcaattg
     2701 ccgtaatgga ggatttgatt gcaaaagatc gagtagacgg aaatgcttat aatcgagaaa
     2761 gtctattgca aatatttggt aagtataata ttcagctaga ttctgatttt gatatggaaa
     2821 aacttcaaga ggaattaaag tccataaaag ggcaaccgtt agcagtttat actataacaa
     2881 tgttgtttaa acgtatgaag cttggatttg atcgttttaa aggtcgaaag caaccaaaag
     2941 caactgctct gtttacagga tcaacagggg tcggtaaaac tgcaatggct aaagccgtgg
     3001 caagaggact ttatggcgat gaaaataaag ttctcttagt taatatgccg gactacaaaa
     3061 caaaagatga tgcaatgcgt tttagacgac tcataggtac tcatgtaagg catgatcctt
     3121 ctgcgattat tgtgtgtgat gaatatgaga aagctggtgt agaaacactc gatgcctttt
     3181 tatcaatttt agatgaaggt aggataagtt ttactgaaag aggatgggat gatcgagaag
     3241 ttcacgacac tgtttcattg tcaaatacaa ttttatttgc gacaacaaat gcaggtgcgg
     3301 agatgttcga ttcgttaaac agatatagct cactatctcg tgttacaaac aaggaaaatt
     3361 ctaatgaata tagcactgaa ctaaaaagag aataccgaaa agtcgcatca gggatcaaac
     3421 aagccttgat tggtgaaggt ctaaagcctg aagttattaa ccgatttgga cgaatagttc
     3481 cattttgggc tttatccgaa caaactcttc tggaaattgc ttataatgaa atgttgaaga
     3541 gtgctgaatt agtacgaaaa catttaaata tagatttacg tcttccacct aggaaagaaa
     3601 gagtatatgg tcaaaatttt tatgcagacg atctctccat gcacttagtt tttgacatgg
     3661 cttcacaaga ggattctaaa tcagggggtg caaggaatat cttgcattta gttgaatctg
     3721 agtttgaaga agcgattact gaagcaataa ttacttatcc aaacgcaaaa atattcgatg
     3781 ttaagttgag tgaagccgga gcgtttgaag gaaaaggtga ttctaatgct gaaattattg
     3841 caaagccttc cgttgctgaa agtaaagaaa acaagattgt attttcgatt ggaggggcgt
     3901 agctatgaaa ttcaagaaat atttactaca aaaccttaga ataaaacgat gggtcgtaag
     3961 aggtctagtt attggaggag tattagcagt tactttaggc gctccttttg gaatgaatga
     4021 tccaactcct gacaatcaag atagcaaaca agaaacagtt ataaataaga acgttgcata
     4081 tgcggaaagt aaaccggcag aacaaggaat gtggacacta tatgctcgta tcctaatggg
     4141 agataaagaa gttaatgata gtgccgctaa aactggacaa atgaatttgt taggacaagg
     4201 tggtatcagt gccgatttcc cttattctga catttctaaa caaggtaatt cgattgcagg
     4261 gggtaatgca ggtactcaac tagcatctac tttagcaact tatagttact acggatatat
     4321 tgaaacagtc tcaggaaatg ctattgccag tcaagcatca tccattctag gaagtattgg
     4381 taggacgatt ggtagtttta tcggatcaat tagtttaatc ctttctaata ttgctgaatc
     4441 cataaatgaa ctccttggaa aatttttcat gagtatgaat atattttctc ttatggggtg
     4501 gggagaaggt ggatcggatg tatctaatcc ggtatctaaa gcattaacta gcttgcttaa
     4561 caatttggga ttaaataatg aattatttaa agcgatagca agcttatcta tgctcttttt
     4621 cacagcaata ctaggttatc aaggaatgaa attattgtcg aaagatggtg ttaactcgaa
     4681 gggattatca ccagtacttg aaaaatggat tgttcgtatt tttgtattgt ttatattctt
     4741 accagtggca ggatcgctat tgggagttta tatcaacggc atccagtcag caaaaaaaga
     4801 tggagatata ccaacaaatg ttgtttctga ctacatcatt aacacaagac tttgggcttc
     4861 tactcaaaat cttgctccat catctgatac tggtggtgat gtacctgacg gaaagcctac
     4921 atccgaaatc aagttcgttg atacagatta tgaaccatct aaaaaatctg caatgataag
     4981 agcgatcaat actagcagtt atgccagaca aaataatgat ctagattcta attcagtcgg
     5041 tatggctcta ttaaaagaat ggtcatcgaa tgatactttc aatattaata cttatgccgg
     5101 tgatgttaat gtcgccgaaa atgatgctta tatgggaaga gcgcctgctg tttggacagg
     5161 ctataattta ggggatggaa aagaaggaag tgcaattaag aaaccaacca atttaaatgg
     5221 atatatttgg tcagcaaatc aaaatgtgac agacgacaat cgcaagcctg atggaaaagg
     5281 aacagcgcat aactttgatg ctactcaacc ttggggcgtt gctaacaatg caacttttag
     5341 cacacagtcg gtagctttat tgctccaatc ggcacttgat acatcgggag ctaagtttta
     5401 tgcgtataat atcgctcctt caggaattca aggcagtgct aagaatatgt caacagtaaa
     5461 aacagaatgg cgtacagcat ccttagttgg tcatggagct atgggtaagt ttggctcgtg
     5521 gctagcgatg aacgctgaat caatcgtttt agcagttctt tacttagcat gtgcttgggc
     5581 gatgttcaat gtgaatatcg tgaaagcatt taaacgtgaa tttattcgga tttgggaagt
     5641 agttctaaca ggatcacttg catcaggagc aggtgtgatg gcaatttcat taggtgttgt
     5701 tacaacatct ctgatcggac tacaattacc tatctttctg attactttta ttcgtgcatt
     5761 tggtgatact gctgtgggat tcattcctaa tacattagtt ggcgatggcg tagcaaatat
     5821 tgttcgatct gctatgattt taggtgtagg atatctttta gtctttaaaa aaggcgaaaa
     5881 agtaaataat ttgattaata tgcttattgg cttaccactt gaagtagcgt ttgggtttga
     5941 tgaacgtgct aagttattat ttggtaatag aaatgatgct gtgcgagttg tggacggcgt
     6001 ttctaaagca atcaagaaaa gccaaggagc taaaaatccc tattatgatg gtggcaacag
     6061 ctcagtaaaa gatatggttg caggaggtct tggagcagtt ggagcgcaaa aaatggctga
     6121 acgtttgaac aatatgggag atagcaatgc tgatgctaag tccattgctg ataaagtaat
     6181 tcctgaaaca ccagaaggaa tgtcattcaa cggtggcgga gttggttcca caatcaataa
     6241 tacctctttc aaagatttag ttcgtcaaga tcaactacgt aataactccc aacaatatat
     6301 tgatcattta ggacgtatgg ttgatgaaaa cggaaacttt gtcgatgaaa atggtgaaat
     6361 attaaaagat agtaaatacg gtaaagatgc taaaggcaac tttattgacg aaaaagggcg
     6421 tttggtcgat gaagatggaa accttataga tactaatggt aaaccattgg aagatagtga
     6481 agatggtaat attggtatgg atagcgaagg acgtttaatt gatgaaaaag gtcgcttagt
     6541 cgatgaagat ggaaatcttg ttgacgaaaa tggacgcagg ttgctaaatg gtgattttgg
     6601 tcatgatagt aacggacgtt tagttgacga aaaaggtcgt ttagttgatg aagatggaaa
     6661 tcttgttgat gagtttggta ataaacttgg taaacacagc gatggatata atgtgaatgg
     6721 agatttagtc gatgaggatg ggaatatcat tgagacgaga gatgcgcttg tggcagatcg
     6781 aaatagagaa ctcgaacaac aacggcatac gccaattgct gttgcaattc ctgagaatga
     6841 agaagacgag attactttag atcaaactca tcaagaactg aggaatgaaa tgagtggtga
     6901 ggacgtgtca gacagagtgc atcgagaatt aggagatgga gcatctggtg aaagtcagtc
     6961 aagagagctt aacagcaact ttgataatag tgctattcgg aatgacacag tacttaaaga
     7021 cagagaatcg ctaacaaaag aaacggataa agaacaatca gatgtgaaga aaaagttcat
     7081 tcctactcct aatgttaatc aaacagataa atatgaaaca aatattggat caggaatgtc
     7141 gaaagacaat caatcaatta gagaacctga actgacaaat aaaaataata gaacaaataa
     7201 ttctaaatct acttcagata attcagggaa atctaatcaa tcaaccaaga aaacatcaac
     7261 agctaaatca gccgttgaat atctatcaaa aactggtaaa aatgtttaca cctcagcaga
     7321 taaagcttta gcaaaagctc caaaaggtag tctagcaggg ataacctatg aagctaaaaa
     7381 cgaagctatt aaaataggta aaggaacggc taaggttgcc aaggctactg ctacaggagc
     7441 atccaaaact ggtaaagtag tgaagaaatc taccatgtca gtcaaggact atattgtaaa
     7501 atacggtaat caaaaatcaa ctgaaaataa gtctgaagac gagtaaaaag aaggagcatt
     7561 gatttgctcc ttctttttac tttgatttct aactgaagat gtcaaggaaa atttctattt
     7621 atgcaaaaaa attattttaa attgtctata
//
LOCUS       DAFLVO010000106         7391 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.108, whole genome shotgun sequence.
ACCESSION   DAFLVO010000106 DAFLVO010000000
VERSION     DAFLVO010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7391
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.108"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(204..1652)
                     /gene="cls"
                     /locus_tag="L1U99_002637"
     CDS             complement(204..1652)
                     /gene="cls"
                     /locus_tag="L1U99_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBN1213147.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGEIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            complement(1804..2697)
                     /locus_tag="L1U99_002638"
     CDS             complement(1804..2697)
                     /locus_tag="L1U99_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1213148.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="L1U99_002639"
     CDS             complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="L1U99_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HBN1213149.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            complement(3472..4573)
                     /gene="prfB"
                     /locus_tag="L1U99_002640"
     CDS             complement(join(3472..4500,4502..4573))
                     /gene="prfB"
                     /locus_tag="L1U99_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBN1213150.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            complement(4699..7233)
                     /gene="secA"
                     /locus_tag="L1U99_002641"
     CDS             complement(4699..7233)
                     /gene="secA"
                     /locus_tag="L1U99_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBN1213151.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
BASE COUNT         1976 a         1639 c         1289 g         2487 t
ORIGIN      
        1 gctatactgg ctttgaaatg tgtctctttt aatagcatat attagcttat ttcttgcttt
       61 ccccaaaaaa caagagatac cccaaagtta atttcgctca tgcgagacgc tttctccatt
      121 tctgacgtac tctcagaaat ggccccgtta aaaaaggaca cgagatctcc atctgttgat
      181 ggttctcatg tcctttttat gttttaaagg agcggcgaaa tcaatcttgc taatccttct
      241 ttcatcttga tgattattcc tcggttttca tacatttctt ttgtgagatg cgtagaaatt
      301 ttcgagtctt caaaaaaagc ttttcttaca cgtgaagcca ttcgttcatc ataaaccagt
      361 gtattgacct caaagtccaa gcgaaatgaa cgaacatcga tatttgctga gccaactgaa
      421 acaatgccac catcgataat catcgtcttt gcatgaataa atccattctc atatgtttcg
      481 atccttgctc catactcgat cagctctgca gcgaaagaat acgttgccca gtaaacgaga
      541 agatgatctg gtttgttagg tatttggata tgaactttta cgcctgaaag aagagccaac
      601 ttcagtgctt catgaatcga tccatccggt atgtaataag gcgtttggat caatatctcc
      661 cgtttggcta acgaaatcat tttcaaataa gtcattttga tttgttcatg ttcggtatct
      721 ggtccgcttg tcacgatttg aacagctata tcaccagtag tgtgaatgga cggaaaaaat
      781 ttgggagaat agcctacttc ttttgtatgc tgagaattcc agtccatcaa aaaacggttt
      841 tgcaaggtat acaccgcttc tccgtaaata cgcaaatgat tgtctcgcca ataaccaaat
      901 ttctttacca atcctagata ttcatttcca acattgaacc cacctgtata tccgatttcc
      961 ccatcaataa ctacgatttt acgatgattg cgataattga tccgaggatt aatatacgga
     1021 acaaatagag gaaagaaaaa tgcgacttct ccgcctgctt ttttcaaatt ctgaaaaaag
     1081 ctggaagaaa cttgtgtgga accccatgca tcaagaagga ctctgacttt tacccctcgt
     1141 cttgccgcct ctgtcaatgc atctcgaact tcttcaccta atgcatcact gcgataaata
     1201 taatactgga agtggatatg gtcttctgcc tgcttgatat cttcaatcag cgcatcgaat
     1261 ttttcacgac catctgtaaa taaagtgatt tcatttttag tcgtatagag cgtactttca
     1321 aataccgtga gcatatagat caattgtttc acatctactt gtccagtagg cggatgagga
     1381 taaagccctc gcatcaatgc ctgtttgtct tcttcaattt ccaggttctt accgattttc
     1441 ccttggatct tcaaatcaaa gattttctct ttggaaatcc ctcttcctaa aaaaatatat
     1501 aaaataaatc ctacaactgg aatgaacatc aaaacgagca gccatgccca tgtttgagca
     1561 gtttcctttc tttctcgaaa aacgatgata aaggaaagca aaatattcat aatcaaaagg
     1621 atcgtaaaaa aattgtcaac gataattttc acggcttcac ctcttcttct accaacttaa
     1681 gaatacccaa gttgtttttt aaagtaaagg gaaaaaagcc gcttccttct attctcctag
     1741 ccaataaaaa aagaaagctg gaacgaaact gtccaacttt ctcattttat ttatattgtg
     1801 gtattagaat ttcaagaaac gtctcataga aatgatcgag ccaagtgaac caatgatcac
     1861 accaatgccg accattaaaa gattgatttt ccaaacgata ttttgtggat gaatcaatga
     1921 ataatgggaa cgtaataatg atggattgat caattggaaa aaccatgcat aaccaaatgt
     1981 gatgatcaaa attggaagaa ttgcaccgat cagaccgatc cagccacctt caaggaaaaa
     2041 cggccagcga atatatccat tttttgcacc gactaaacgc atgatttgaa tttcacgctg
     2101 tctagacaaa atcgtgatcc gaatcgtgtt cgaaatgaga aacatcgcta cgaacagcag
     2161 caatgccgct gcaactaatc cccatgtccg aactgcacca gcgatttgga aaatccgatc
     2221 tgaggaagct ccaccgtaat cagaacgaga aacattcttc aaatctgctg cttcttctgc
     2281 tacttgtttt gtataagaag gatcagtagc acttactaca tacacatcat ataacgggtt
     2341 attgtcacct tcaaacaatt tccaggaatc acccatttcg ttttggattt ttttcaattc
     2401 ctgttctttg cttgaaaatt caactttttt aacatgatct aagtcattca attctttttc
     2461 tagctttttc atctcttcgt cttttgtacc gatatctacg aatacagata catcaacgtt
     2521 tccttctata tcctgagcta atttagttgc attcatgata actgccatga atacaccgac
     2581 taaagtcaac gtgatcgtta ccgcactgac tgaagcaact gtcatccagc cgttacgttt
     2641 caaactcttg atactttcta ataaatggcg gaaaaaggtt ctaatcatcg tatccatatt
     2701 ccccttccgc ttgatctcga ataatgcggc cgttttcgat agcaattact cggtgccgaa
     2761 tcgtatttac gatcgtactg ttatgtgtag ccatcacgac agtagttcct tgggcattga
     2821 tccgatctaa taatttcatg atttcccatg agttttctgg atccagattt cctgtcggtt
     2881 catccgcgat aagtacttta ggcgtattca cgattgcccg agcaatagag acacgttgct
     2941 gttccccacc ggataattcg ctaggaaaga ctcgaacttt gtgtttcaaa ccaacaaggt
     3001 ccagcacttc cattactcgt tttttgatat ctcgaggttt tctgccgata acttgcatag
     3061 cgtacgcaac attttcatat actgtttttc ttggtaataa tttatagtct tggaacacca
     3121 cgccgatttc tctgcgtaga taaggaactt cgcggttttt gattgctatt agatcatgac
     3181 ctgcgacgtt caaagttcct tttgaagctt tttcttctcg atacatcaat ttgatgaatg
     3241 tagatttacc ggctccagac ggaccaacca catagacaaa ctctccttgt tcgatgacaa
     3301 tcgagagatt gcggatagcg gtcgtaccat ttgagtactt cttcattaca tccttcattt
     3361 caatcatggc gttctctcca tatctttttc agtctttagc tattatagca tggcaatgtt
     3421 tcaacatgct tgcaaaatct tacaatttta tttcaattta acaatgggtt cttattgtag
     3481 atgcattttt aaatagccgt caataaataa atcaaggtca ccgtccataa ctgcttggac
     3541 atttcctgtc tctacgtttg tccgatggtc ttttaccata gaatagggat ggaaaacata
     3601 agaacggatc tgtgaacccc agccgatttc tttttgttct cctcgaagtg cagctgcttc
     3661 ttgttctttc ttttccactt ctaattgata aagcttagct tttaacatcc ccatcgcttg
     3721 ctcacggttt ttcaattgtg agcgttgtgc ctgactagct actactgttc ctgtaggcaa
     3781 gtgagtgatc cgtacagcag attctgtttt attgatgtgc tgaccacctg caccacttgc
     3841 tcggtacgta tcgattttca aatcatctgg attgatttct atatcgatcg tttcatcaag
     3901 ctctggcatc acatctaccg aacaaaaaga agtatgacgt cgtttcgctg agtcaaaagg
     3961 cgaaatccgt acaaggcgat gaacaccttt ttctgatttt agataaccaa aagcgttatg
     4021 tcctttaatc agcagggtca cactcttgat ccctgcttca tcacctgctt gataatctag
     4081 tgtttctact tgatagccat gctgctctgc ccaacgtgta tacatacgta aaagcatgct
     4141 gccccagtct tgggactccg ttccgccagc ccctggatgc aattcgacga tcgcattgtt
     4201 tcgatcataa ggtccgtcta acagcataga taattcatac gtcttcattt tttcatctaa
     4261 tgcattgata cgtgtttctg cttcttcttg cattgctgca tcaggttctt cttgcagcat
     4321 ctccaccatc aattcgattt cttctagttc ttcggcaaga gaatggaatt ggtcataggt
     4381 ttctttatta gcgttatttt cgctgatcac tttttgtgcg gcttcgctgt catcccaaaa
     4441 accaggttca gccatttttg cttctgcttc cgcgatgtct tcttccagct gatctaagtc
     4501 aaagagacct cctgaaactt gtgacctttt cctgcatttc tgtcaggaga tttcgaattt
     4561 cggatatttc catgtttttt ccttctttca ctatactttt ttcattatat ctagtctaac
     4621 agaatcagca aataacagaa agaaggtgag acgaattctt aaaaaaagaa tttgtctcac
     4681 caatcctgct gtcagaaatt agtttgcatt ttttccatga cagttcttat attttttccc
     4741 gcttccacaa ggacaaggat catttcttcc gaccttattc acatggattg gctgtttttt
     4801 cgcgctagta ttactatttt ctttggcatc tccgtcttct gagtgagaag ctgttccttg
     4861 agaaacctgt tcacgctgta cgttttgacg gatctcagct ttcataaaga ttcgagtgac
     4921 ttcatactcg atggcgccta ccatatcttc aaacatctta tagccttctg tttgatattc
     4981 gactaatgga ttgttctgtc cataagcacg taagccgatt gactgacgta attgatccat
     5041 tgcatcaata tggtctgtcc atttagagtc cacaacacgc aagatcacga ctttttcaaa
     5101 ttccaacagt tgctctggac catttagttg agccgctttg gtattaaata cttcttgtgc
     5161 tcgttcgttt agatactctt tgatctcctg agctgttttt ccttcgatat ctgcaagagt
     5221 aatgctatct tcatggacaa gagtactgcc ggcaaaatcg atgatacttt ccaaattcca
     5281 attttctttc tctaattgtg tatgcgcatc tactacacga ctgattgtcc gtttgaccat
     5341 gttcattagt ggcttggata agcttttttc ttccatgatt acttcttgtc gctgtttata
     5401 gattacttca cgttgttcac gcatcacatc atcgtattgt aagacgtttt tacgtgtgtc
     5461 atagttattt ccttctacac gtttttgtgc agattctact tgtttcgtca gcatcttgct
     5521 ttggataaca gcatcttcct caccgatctt catccgatct aagaaagctt tgattcgttc
     5581 tgaaccgaat cgtttcatca aatcatcttc caatgacaag tagaactgtg acataccagg
     5641 gtctccttga cgtcctgcac gtcctcgaag ctggttatcg atacgacgag attcatgtcg
     5701 ttctgtcccg ataactgcta gaccaccaag ttctcttacc ccaagtccta acttgatatc
     5761 tgttccccga ccagccatgt tggtagcaat cgtcacagca cctttttgac cagcattcat
     5821 gatgatctct gcttctttaa agtgattttt cgcattcagc acttcatgag gaatacgttc
     5881 ttgattcagc atatctgata ataactcaga tgtttcaacc gcaacagttc cgactaacac
     5941 aggttgacct ttgcggtagc gatctttgat atcttgcacg acagcgtgga acttgctttg
     6001 taatgttggg taaagcaaat ctggacgatc atcacggata accggacgat ttgtcggaat
     6061 ctggtatact tggatgttat aaatttctct gaattcttct tcttctgttt tagctgtacc
     6121 agtcattccc gcaagtttct tgtacatacg gaaatagttc tggaaagtga tcgtcgccat
     6181 ggttttcgtt tcgtcttcga tctctacgcc ttctttagct tcgattgctt ggtgaagtcc
     6241 atctgaataa cggcgtccat ccatgatccg accagtgaac tggtcaacaa tcagtacttt
     6301 tccgtcttgg acaacataat cgatatctaa aagcatgata tagttggctc tcaatgcttg
     6361 atccaagtga tgggtcaatg cagtattttc aatgtcgtat aagttatcca aaccgaatgt
     6421 ttcttctgct ttttcgatcc ctgcttcggt taaactgatt gtttttgatt gtacatcgat
     6481 tttataatct tcttcttctt tcaaacgttt cacgaagttg tctgctcttg tatataaagc
     6541 tgtggatttt tctgcttgcc ctgaaatgat cagcggcgtt ctcgcttcat caatcaagat
     6601 tgagtcaact tcatcgacaa tggcataatt cagcggacgt tgtaccattt gatggcggta
     6661 aacgaccata ttgtctctca agtagtcaaa tcctaattca ttattcgtac tataagtgat
     6721 atcacaatta taagcctcgc gtttttcatc cgaagatttt gagttgatat tcaaccccac
     6781 tgttaatcct aagaaattat aaagttcgcc catttccgtc gagtcacggg ttgctaaata
     6841 ttcattgacg gtaactacgt gtaccccttc gccagtcaga gcatttagat atactggcat
     6901 cgttgcggtc aaggttttac cttcaccagt acgcatttca gggatatttc catcgtgaag
     6961 cacgattcca cccatcaatt gtacgtggta tggatataaa cctaatacac gttttgctgc
     7021 ttctcggacg actgcaaaag cttccggaag taattgatct aatgtttctc ctttttggta
     7081 tctgcccttg aattcagcag tttttgcctg taattgttca tcagttaatg ctgccatttg
     7141 gtcagcgtat gcttcaactt tttttgcaat gctatctaaa cgttttagtt ctttcttatc
     7201 gttttcgata agtgaacgaa tcaaattggc catgcgttgt gtaatctcct tttccttctg
     7261 tgtattatcc agactatgta gactttactt ttcattttat cattagttat agataattga
     7321 aatatcttaa gcgtattaaa gtaagaactt cataatttat tcatatttca tctaaaagag
     7381 gaggaaactc a
//
LOCUS       DAFLVO010000107         6993 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.109, whole genome shotgun sequence.
ACCESSION   DAFLVO010000107 DAFLVO010000000
VERSION     DAFLVO010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6993
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.109"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            17..2344
                     /locus_tag="L1U99_002642"
     CDS             17..2344
                     /locus_tag="L1U99_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBN1213152.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            2470..2799
                     /locus_tag="L1U99_002643"
     CDS             2470..2799
                     /locus_tag="L1U99_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBN1213153.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            2839..3843
                     /locus_tag="L1U99_002644"
     CDS             2839..3843
                     /locus_tag="L1U99_002644"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBN1213154.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            3840..4286
                     /locus_tag="L1U99_002645"
     CDS             3840..4286
                     /locus_tag="L1U99_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBN1213155.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            4436..5251
                     /locus_tag="L1U99_002646"
     CDS             4436..5251
                     /locus_tag="L1U99_002646"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBN1213156.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            5457..6629
                     /locus_tag="L1U99_002647"
     CDS             5457..6629
                     /locus_tag="L1U99_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBN1213157.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(6839..>6993)
                     /locus_tag="L1U99_002648"
     CDS             complement(6839..>6993)
                     /locus_tag="L1U99_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213158.1"
                     /translation="QQSAAEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTY
                     TPATLS"
BASE COUNT         2451 a         1309 c         1398 g         1835 t
ORIGIN      
        1 tttattgaga ggagggatga aaatgattaa gaaaactcaa aataaaatcc aacgtatatg
       61 tcaaaaacat tttgtttcta gactcaaagc tgtatctaaa agaaaatact tacatcccat
      121 tatgatttcg atcatcttga tttttacttt cttagggagc ttatcaagta tttatgtaaa
      181 cgtttataca gaaacgtcaa attttgctaa ccaaacgaca gaggagacaa atagtccacc
      241 ctattctgaa atacagtcca tagaaagcac caatcagtct agcaacaacg agacaacctc
      301 aaccacatcc tcgactcaac tgattgatcc gacagaaaaa gaaatcacag cagcaaaagc
      361 agcaggggag aaagcttatt cagaaacagg tagaagccag acatttagta ctgttgcggc
      421 cactgcgaat ttcaacggac ataccatacc agatggatat acagtgatat atgccaaaga
      481 tggagtcatt gttgcggtta acggatcgat gagtgcggat aaaactgcgt tacaaggcgt
      541 aaccaaagca atcgctttta ttgataaccg tccagatatc cataatctgt ttattggctc
      601 cacagtaaat ggtactacta tcacattccc aaaaagtatc tatatggggg tggctaccgc
      661 tggaaatacg atcgattcag ttacacccaa tgcggataaa agttattctt ttacaccctc
      721 aacatgggga gggcttcctg ccggaggagg tatgagtact ttttcaatcg gtatacagtt
      781 agcaaatgat attccattca cggggtactc gatcaaaaat gggcagatcg ttgatggtaa
      841 gggaaatgtt tcaaattttc caacctatca agcagcaacg gttcaggtca atgcgaatcg
      901 gacaggaact ttttcttata cagtcaatgg tggagcagca aaaatcggaa cgtacgggac
      961 tacattatct ggaatccatg tgggtgacaa agtggttatc actccaacag cagtaacggg
     1021 ctattctttt gcacaaacaa acggttcttt cacagcccta gaaagtaacg tcgatacggt
     1081 gacctataca ggcaaacaaa caccaatcac tattaagtat caagactatt ttggacagat
     1141 gattgctcct tctaaaataa tgaatcttac ttacggaagt gctgcacaag acctgacgac
     1201 taatacgcct actatcaacg gatatacctt tacagctgtt tcagcgatag aaacaaagaa
     1261 ccaatcagca atgagtgttt tagctagttt agatacaaat ggaaatgtaa tcgtaaagga
     1321 cgcaaatgga aaacagattt ctgaagtcat cctatattat aagacaaatg caacagtatc
     1381 aatcaatgca aatggcagta agtactatga tggtctttct gttgtaccga tcgttaaata
     1441 tgcctttaat gataaaacag aatcaacatc ccttttaaac aatgatctca gtattgatca
     1501 aatcacatgg aatccaactg atttcaaagc gatgaatgaa aagggagttg aagtaactgc
     1561 gcctactgaa attggaacct atacgtcttg gcaattgaca aaaagcggac tagctaaact
     1621 agctgccaga acaaactatt tatttactat cgtgcagaca tctgatgtct atacgattaa
     1681 gcaaatcagc ggtgcggtag agctcagtgg cagtaagaca tatgatggaa aagcaggtgt
     1741 cccgtcaatc catgtcaagc tagcagaggg tgtcactagt tcgcttactc cagtacaagt
     1801 ggcacttagc agtatggatt acacagcaga tgcacaatca gcaaaaaata tggttaatgc
     1861 tggcagctat acaattaaac taacgaatag cggaatagac aaagtcaaag cagcaaatcc
     1921 caagttgtca tttactgata tagccaacac atcaggaact tataccatct ataaagctaa
     1981 cgcagtgatt actgtcgatg acgctgcctt taattatgat gcccaaagtc actcgatttc
     2041 ggttggaaat ctccacgtta ccggtgttgt cttaggcgaa tcattggatt ataccctaac
     2101 agttaacagc cggacagata ttggatcaca aatagtaacg attagtttag gcgaaggaag
     2161 tgtaaacaat aattatacga ttatcgcaac agataccgct aagttgacga tcaatccgac
     2221 tctcttgctt ccttcgacag gtgggatagg tctactgccc tttgtctttt taggactgat
     2281 ctttattttt tctggcttct tttattttat ccatcgtaag aaaaaagcag gtgaacagcg
     2341 atgaaaaaaa caaaaaatgt acgtgtggat atatttgctg ttctcttttt tatcctactg
     2401 gtctttttta taggttctcc gactgtgtca gctagagaat cacctattac atttactttg
     2461 cataatcgaa tgttcgaaag cgataagatg ccaagtatca gtcaaaacga cggaataaat
     2521 atcccggata actttcaagg agtaaaaggg ttgaacggcg ttactttcgc tatatatgat
     2581 gtctcggatg aattttacaa gctgcggtca gaaggaagta gtgtggaaga cgcacaaaga
     2641 aaactagcac aaaaaagtga tagtgaaaaa atactggcag aaaatgtgac aaaaacagta
     2701 gacgaggaag agggcattgc ttcttttagt gcatcggaca aagatgagca aggtcgtgac
     2761 gctgtttacc gatttacgga aataaagact tcagattaag taaaagaaaa atcagcacca
     2821 tttgtcgttg tgcttcctgt gacagattca tctaatcata aattgacgac catccacttg
     2881 tatccaaaga gcgaacaaaa aatacctgct gcactcacat taacaaaaac agtagagaat
     2941 aagcagacag attttgcaga tggggataaa gtcccttatc tcatcaccgt aacaattcct
     3001 gagaacatca acgagatagg aacctatacg atcaaagata cagctgatcc tcagttatgg
     3061 ctagaaccag aaacgatcga ttttttgatt ggtggagaca agattcatac atttcacaca
     3121 caaaaaataa aacatggttt tgtcttatca gattctggaa aagatcttag ttcgtttgct
     3181 ggaaaaaaat taacgatccg ttaccaaatg acattgaaag aaaacagtga aaaaacgaca
     3241 tttgataacg atgtacgttt gacgactgac aatcaaacag tagaaacaca tcttgccatc
     3301 caaacaggag gcaaacaatt tgtcaaagtg gatcggcaaa cgaaacaaaa actagcagat
     3361 gctcaatttc tagtcaaaaa aaatgaccaa tacttagcgc aagaaaacgg gataaatcat
     3421 tgggtagcca aagatgattc aagagcaacg atttttactt ccagtaaaga tggaacattt
     3481 tctgtccatg gattgtcttt tggaagttac gaactagtgg agattaaacc gcctaaagga
     3541 tatatattga gtcaatcaac cattctcttt gaagttgaaa aaggcagtta tgatccgctt
     3601 catcctatac cattggaaat catcaacgaa ccaaaagcaa atccgacgaa taatggaaaa
     3661 acgccagttc agatgcagac aaatggtcca tcaaatgaaa aaaatggagg aagctttcca
     3721 aaaacaagcg aagagatgct tggaggtttc tcaattttag ggttattgct agtcctttca
     3781 acagggacag cttggtttta taaaaaacaa caaaaaggaa acaataggag ggaaataaaa
     3841 tgaaaaacat caaaacaaaa atatggacgt ttttaggaac tgctatcatg ctgcttcctt
     3901 tcgttctcgg cctaggaact gcagaggttt ctgcagccgt atcacctaca ccagaaaatg
     3961 ttacggttaa tttgcataaa ttgaaattca cttcagcacc agaaaatcaa ataaacaacg
     4021 gaacggaatt gacatttccg aatagcgaac cgttgaacgg cgttgaattc aacgtatatg
     4081 acatcactgc tacgtactat ccaagtaaag acacagcagt tccagcagac gctacaccct
     4141 tcgcaagtgt aacgacttct ggtgaaggat tagctaacct gactcttcca ggtaaatctg
     4201 atgggaaaga tgctgtatac gtctttgtag aaacaccaaa gcccggtgtc gaaacgtcgc
     4261 caaatatcgt gttaagctta ccctagaccc tgacaaacct ttagacacga ttcacctata
     4321 tgctaaaaat gtcatcaaag aaagcaatat caaaatccag aaagctggga acttttcagg
     4381 ggtagataag ttagcagggg cgcaattcca gatcaaaaat tcagagaatc aattcgtgac
     4441 cggttttgat gaaaacactg gtgtcgctct ctatgatcct gctgagtcag cgttgacatt
     4501 cacaactgat actgaaggat ccatcagtgt caatggatta atagacggca attatacttt
     4561 agttgaaaca aaagcaccag atggttatca attaaccaat ccacaaaaag aaactacttt
     4621 tatagtaaaa aacggaaaat tgcaacaaac aaccggtatc atccatggcg cagatgaagc
     4681 caatcttggg aatccaaacg gtgtagtcaa tcgggaaaat acaactacgg ataacacgat
     4741 tactgtagaa aatgtccaaa actacggtga tttccacttc atcaaacaag atgtgaacac
     4801 gcaagaaaaa ttagccgatg cagaattttc tattctaaga gcaaaagatc caactgttaa
     4861 attaatgaaa aaaatagcaa accttgcctc aggagaatac ccatatgctt ggtcagatga
     4921 agtcacaggt tctgactggg aagaagtgaa attgatttct gattcagaag ggaaattttc
     4981 aatcgaaggg ctgaaacaag gggcatactg ccttcaagaa acaaaagcac cagaaggcta
     5041 cgcattacct aagaatgaag ctgcgtacac tgaatttaca gtagatgatg atccaacaac
     5101 ttctgatgaa acaacgatcg ataaccaacc taaaggaatc ttgccttcaa ctggtggtat
     5161 ggggatcatc gtattcatct tggtaggtac tgctttagtt ggaggagcag tgatctattt
     5221 caaaaaacgc catcaagaaa cagaagctta aactattgga aacaaaaatc atacgataaa
     5281 taaacgatag tgattcaaat ggggagaaag gttgtgacaa gtggtcggtc tcttggtatt
     5341 cgctcaacaa acggcaaaat aggaggaact attttgccgt ttgcttcgct aatactcagg
     5401 tcaaggcgct gatttcacaa cctcttcata tacatattag aaaataggtg gacatgatga
     5461 ataaaagcag aataagaata ctggacatct tcatggcaat cattttagtc gttgggatcg
     5521 ggatcttttc ttatcctttt gtagaagatt cactgaatga ttttcttgcc cagcaaatga
     5581 tcatccatta tcaaaagcaa gcatcgaata agaattcaga ggaaataaaa aaacagcagg
     5641 aaaaaatgac aaagaaaaac caacagttgg cagagcaaaa cgtatcacca gggataggca
     5701 gtttcaacca agcagttgat gcaaaagcat taaaagattt acctagtaat gcctttttta
     5761 tggaacatat gcttggagtc atcgaaatcc caaaaatcaa tgtcagctta cctatattcg
     5821 atcagacaac ggaaatattt ttgcaaaaag gaacgtcatt attggaagaa agttcttatc
     5881 cgactggcgg gaaaaacacc catgccgttc tttctgggca tcgtggactc ccagaagcaa
     5941 aattatttac agatttgcct aagttgaaaa aaggagacca gtttttcatc cagatcaatg
     6001 gaaagacatt ggcgtatcaa gtagaaaaaa tccaagtggt cttacctgat gaagtagatt
     6061 ctttgggtat ccaaaaaggc agagatctcg tgactttgct tacctgtact ccttatatgg
     6121 tcaatacaca tcgactgctt gtgacggggc atcgtattcc ttatcaagca aaagaggcaa
     6181 aaaaagcgat ccaaggaatt gatcaatgga aaaaatggaa attttttatt tggtttatcg
     6241 gtatactact tggatcaatc ggcttagttt ggctactcat cgcttattta gattctttgg
     6301 ccatcgctaa gcgaaactat cctttatctt tttatgtaaa gaacacaaac ggacgaccaa
     6361 tcgaaggaat ggtcttttct gtaaaaacgc tcaacggcaa acactatatt actagagaaa
     6421 aagttccatt tgtgaaagct tctgatgaat acggactagt gagattttct gatttaaaag
     6481 gcaggaacta tcgcttgcaa catgaggagc tcctgcttaa aatccatgta aaacataaac
     6541 attcgaaaca gttttcaatg aaattgaaaa aaggaagata taaactgcga aaagaaaaag
     6601 aggtgtacta tttgattgag aaagaatgaa tgaagatgtc caaaaaagca gagggaacag
     6661 actaaatgaa aaaagagaga agctgacgaa atggacgtgt aaactgttat ttttggttta
     6721 ctatctggaa cgccatcttc tattttttta tgtttcagaa gaattttatt attatagtat
     6781 aacttttgaa ttagtttcca taacatttgg agcaaggggt taaaccacga gcttgagctt
     6841 agcttaaagt ggcaggggta tacgtaccat ttccacattt atgtgtatgg tattttgaac
     6901 cggtcggtgt gacatagaca gtttgttcat tattttgctc aggagctgcg gcttgtgcct
     6961 gctgagaggc ctgttcagct gctgattgct gtc
//
LOCUS       DAFLVO010000108         6554 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.110, whole genome shotgun sequence.
ACCESSION   DAFLVO010000108 DAFLVO010000000
VERSION     DAFLVO010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6554
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.110"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            70..2745
                     /locus_tag="L1U99_002649"
     CDS             70..2745
                     /locus_tag="L1U99_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HBN1213159.1"
                     /translation="MKMNHTSIQKHLQLLNTLGISYVNLRTFSTLNKKTVSHIFSTAD
                     SQAIINYLEKQKLSEGTVNITYNPIKQEVITQKKHSVRDNDIEKIRFVFIDIDPKRKE
                     GSATDSEKKKAENVMEQVERYLKEKRIESFVKVDSGNGYHIFLPINEQPNNHETILTI
                     QNFLQLLHRRFGVEDEVDIDTSVYNPSRLCKLVGTPAVKGKSTKERPHRLSSFLSIPD
                     NIDRSNCFKILEQIVEENSMMSTSRVKSHPSFREVLPFIQADYKQWLAHYPELTYTIK
                     EGDHKGVTLLIFDECPLRKHTNNSNGSCLSVTADNKIRFHCLHASDKNKDIQDFVKKY
                     PLPKPVNPSVESLESNQEYYFDQFKLNQEGVFLVKEGQEEKVACPMFIKQIRKNIEQK
                     VITLVLAYYVDHCWDEIEIEGGCLQTNNFKQLAKHGLIIKARREAEVVDFLQIQRENA
                     PIFFEHESLGWKKENEAMIFQLQDSFGREIPSVLTKNSCYQLTTNGTEAEFDALVHKY
                     VLGTNLELAWSIGIASIVLGYLNVTKANTFLSLLINLQGKSTTGKTTTLHFIASLFGN
                     PTTVLRNMNATNKAIIKLASNNQGGVPLILDELGAATQNNFSSLIYQLASGEERLRLD
                     SNCQLMPQETFSVLTLTSSEERLENYFNEKLTGLKVRYIEFSDIKFTKDANHAEKVKS
                     LSSNTFGWGIKLFLLKLFEQGITKIEATFVEAQKKLWAVLPEHSLKQRIGNNLALIYS
                     GALLIQDILGYPLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLT
                     NSDNKHTPSTIWGKVSIQKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNM
                     CAEKGRRTKRIHMNRQVLPTYEILLPSSLKSYFRL"
     gene            2927..3166
                     /locus_tag="L1U99_002650"
     CDS             2927..3166
                     /locus_tag="L1U99_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213160.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLDFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNRRVVKKWYLVHS"
     gene            3182..4555
                     /locus_tag="L1U99_002651"
     CDS             3182..4555
                     /locus_tag="L1U99_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1213161.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGEKAERPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLSYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEVHEARIVRYIFQLYLTKKYGYKKLCQRLTQQKLFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKATFLQAQEIRQSRCTAKKDTYLYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKRKVIQQKKQEAQWIKAFEEGNCSLEELKQQLQALQ
                     KPMSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDYVCRIEVTKDKTVCGIYFRQLTQ
                     NILERNE"
     gene            4559..6193
                     /locus_tag="L1U99_002652"
     CDS             4559..6193
                     /locus_tag="L1U99_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1213162.1"
                     /translation="MEMIQTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMGYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPRPILVKGTHEPIISEEDY
                     QKVQERLALEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQGEPIQVKDVQRILTSLDRFLAQSEKKQIKALYRTFIEKITFDPNHKEMLEITMK
                     FTHAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            6356..>6554
                     /locus_tag="L1U99_002653"
     CDS             6356..>6554
                     /locus_tag="L1U99_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213163.1"
                     /translation="MKKMGKCILCEKYTELTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYY"
BASE COUNT         2300 a         1062 c         1319 g         1873 t
ORIGIN      
        1 gaaattatga gaggttggag gtaatgtagt catacaaata aaaatttttt agaaagtgag
       61 tggtaattaa tgaaaatgaa tcacacttca attcagaagc atttacaact gttaaataca
      121 ctggggattt cttatgttaa tttgagaact ttttctacat taaacaagaa aaccgtttct
      181 catatttttt ctactgcaga ttctcaagca attattaact atttagaaaa acagaaattg
      241 tctgaaggta cagtaaacat aacttataat cctattaaac aagaggtgat tacacaaaaa
      301 aagcattctg tgagagacaa tgatattgaa aaaattcggt ttgtatttat tgatattgac
      361 cctaaaagga aagagggaag tgcaacagat agcgaaaaga aaaaggcaga aaatgttatg
      421 gaacaagtag aacgttattt gaaagaaaag agaatagaat catttgtaaa agttgatagt
      481 gggaatggct accatatttt tcttcccata aatgaacaac caaataatca cgagacgatt
      541 cttactattc agaattttct tcaattactt caccgaagat ttggagtaga agatgaagtt
      601 gatattgata cttctgttta taatccttca agattatgca aattagttgg tacaccagcg
      661 gtcaaaggaa agtccacaaa agagcgtccg catcgtttat ctagtttcct ttctattccc
      721 gataacatag atagaagtaa ttgttttaaa attcttgaac agatagttga agaaaattcc
      781 atgatgtcaa cctctagagt aaaaagccat ccatctttta gagaagtgtt accttttatt
      841 caagcagact ataaacaatg gttagctcac tatcctgaat taacttatac cataaaagag
      901 ggcgatcata aaggagttac cttacttata tttgacgaat gtccattaag aaaacacacg
      961 aataattcta atggttcttg tttgtctgtt acggctgata ataagattcg atttcattgt
     1021 ctgcatgctt cggataaaaa taaagatatt caagactttg taaaaaaata tccgttgcca
     1081 aaacctgtaa atccttctgt agaatcatta gaatccaatc aagaatatta ttttgaccag
     1141 tttaaactga atcaagaagg agtatttttg gtgaaagaag gtcaagaaga aaaagttgct
     1201 tgtccgatgt ttattaagca aatacgcaaa aatatcgaac aaaaagtcat tacacttgtt
     1261 cttgcctatt atgtcgatca ttgttgggat gaaatagaaa tagaaggtgg atgtttacaa
     1321 actaataatt ttaaacaatt agcaaaacat ggcttaatca ttaaagctag aagagaagct
     1381 gaagtcgttg actttttaca gattcaacgg gagaatgctc caatcttttt tgaacatgaa
     1441 tctcttggct ggaaaaaaga aaatgaagca atgatttttc agttacaaga ttcttttgga
     1501 cgtgaaattc cttctgtatt aactaaaaac tcatgctacc aattaacaac taatggtaca
     1561 gaagcggaat ttgacgcatt ggttcataag tatgttttag gaacgaactt agaacttgct
     1621 tggtcgattg gtattgcttc tattgtgtta ggctatttaa acgttacgaa ggctaatact
     1681 tttttgagtt tactaattaa cctacagggc aagagcacaa cgggtaaaac cactacgtta
     1741 cactttattg cctctttatt tggaaatcca actacggttc ttagaaatat gaatgctacc
     1801 aataaagcca ttataaagct agcatcaaac aatcagggag gtgttccact aatactagat
     1861 gagttaggag cagcaactca aaataacttt agctcgttga tctatcaatt agcttcagga
     1921 gaagaaaggc taagattaga ttctaattgt cagcttatgc cacaagagac tttttctgtt
     1981 ttgaccctta cctcttctga agagcgtttg gaaaattatt tcaatgagaa attaactggt
     2041 ttgaaagttc gatatatcga attttctgat atcaagttta caaaggatgc gaatcacgca
     2101 gagaaagtta aaagtctttc ttctaatact tttggttggg gtataaagtt atttcttttg
     2161 aaactctttg aacaagggat tacaaaaatt gaagcaactt ttgtcgaagc tcaaaaaaaa
     2221 ctatgggctg ttttacctga acattctttg aagcaacgca ttggtaataa tctagctttg
     2281 atttatagtg gagccctcct aattcaagat atactgggct atcctttacg attagagcat
     2341 atacagacgg tgcttattaa ttcgtacgaa cagttaattg tagatactag tttaggaagt
     2401 gagcaaacgg tatttgaccg agtgaaaaca ttgttggtga tgaatagcca taaattttta
     2461 acaaacagtg acaacaaaca tacgcccagt acgatttggg gaaaagtatc aattcaaaaa
     2521 aatggggata ttaaggtaaa tatttttcct atcccgtttg aggacttgtt aaggcgagaa
     2581 tttcaagtaa aggatctaac ctatcttttt aggcaattgc ttgattcggg taatatgtgt
     2641 gcagaaaaag ggagaagaac gaaacgtatt cacatgaatc gtcaagttct tccaacatac
     2701 gagattctat taccttcttc actcaaatcg tattttcgat tgtaatttag aataaaccaa
     2761 agtatgaaag tgaggcacca tgttatggaa atatttctta ttgatttagc aaaacaactg
     2821 attacttatc tgtatgatag cgagcaaacc caaacggaag taaatgaagc ttgatctatg
     2881 cttcatttac ttcattcaat caaacatgaa agaaaggaaa attctaatga ctaaaaataa
     2941 aatgacacta aaagcagagg ttcttctgta tattcaagaa catttttcaa atcaagcctt
     3001 ttttacaaaa ccaatttact tggatttcga aataagaggg gtatctgctg gatctatcgg
     3061 gggtactctt caagcgttga agaacgaagg atatttagaa aatcactttg tgcaacgttc
     3121 gttcaataga agagtcgtga aaaaatggta tttagttcat tcatagagag gggaatcaag
     3181 catgcgtgtg gcttgttatg atcgaacgtc tgtttatgaa gaagcgaaaa ttagtaatga
     3241 cgctcaatat gatgcagtga aagagtatgt tttagagaaa tatgaacaaa ttccccaacg
     3301 attttcagac aaaggagaat caggggaaaa agcggagcgt ccagcttttc gacagcttag
     3361 agcttgggtt tgtgcgtcag aagaagaggg ggtgatctat gtttggcgtt atgatcgatt
     3421 ggcacgtcaa gccaaaatag ccttagaatt tattgagttg tgccaacaac atcaggttca
     3481 agtgtattcg atttctgaac ctcttcctgc ttctttctca cacgcgtcaa cgaataaact
     3541 atttgtgcaa ttattgttca cttttgcaga acaacaacga aacgtcatta ttgagaatgt
     3601 tcgtgccgga ctttcctata aaaagcaaca acggcaatat ttgtcttctg cggtaccata
     3661 tgggtatcgt ttagtgaatg ggaaaatcca acaagaagta cacgaagcaa ggattgttcg
     3721 ctatattttt caactttatt tgaccaaaaa atatggctac aaaaagcttt gtcaacgatt
     3781 gacgcaacaa aagcttttct tccgcgaacg tccttttcag ccctatcata tttatagtat
     3841 cctaaaaaat ccattgtact atggcgaaat caaaggagga tctttgggga agtatctagg
     3901 aacctttgaa ccgattctct cgaaagcaac ctttttacaa gcccaagaga ttcgccaatc
     3961 aaggtgtaca gctaaaaaag atacgtatct gtacttatta cgtcaaaaaa ttcggtgtcc
     4021 cttctgtggt cgtcatctga gttcgaagta tcaatggaat acaaagaaga cgaagacgct
     4081 tcattattat cattgtaccg accgaagctg ccaaggaatt tttcttcggg cagaaagggt
     4141 tgagtcagaa gtattggaaa agatacaggc tttttttcaa tacgaaggcg tctatcaagc
     4201 cttgattgcc caattaacgc aacaattagc cgaaaagcga aaagatgaaa aacgcaaagt
     4261 aatccaacaa aagaaacaag aagcacaatg gattaaggca tttgaagagg gcaattgttc
     4321 actggaagaa ctcaagcaac aactgcaagc tcttcaaaag ccgatgtcta cttcttcgtt
     4381 tctttcactc caacagtgtg aagcaaaagt gaaagaatgg cttcaactaa aagacctctc
     4441 tagtcgacaa ttattatgtg actatgtttg tcggattgag gtaacaaagg ataaaacagt
     4501 ttgtgggatt tacttccgac aactgacaca aaatatttta gaaaggaacg aatgatctat
     4561 ggaaatgata caaaccaaac gagtcgcatt gtatattcgc gtgagtacac aagaacaagc
     4621 tttagaagga catagtattc aagcacaaga acaaaatgga cgacagtttg ccgaacggat
     4681 gggctatgaa gtggtagaag tttatgccga tgaaggaatc agtgggaaat ccacaaaaaa
     4741 tcggttcgcc tatcaacgaa tgatgaacga tgctcggaac catcgttttg atctactagt
     4801 gatttggaaa ttgacccgtc tcggacgcaa tatgttagat gtcttacaaa cagtcgagga
     4861 attattgcga tatgacgtag gattacattc gatctcggaa caatttgacg tgaccacttc
     4921 gacaggtaaa ttgatgttac aactccttgg gagtttcggt gaatttgaac gcaaccaaat
     4981 tgcggagaat gttcaaatgt caatgcaaag cttagtgaaa gataaaaagc gttatgcagg
     5041 aggccgacgt ttaggctatg tcagtggtat tgacacgaat ggtcaaaaac aattggtcat
     5101 tgaaccagaa gaggcgaaaa ttgttcgtct gatctatgca aaatatttag gcggagcagg
     5161 gtatcgagcg attgccaatt ttttgaatcg tcaaggatat caaacagtca aaaagaatgc
     5221 tttttctacc acggcagtca aagatatctt acgcaataaa atttatgcag ggtatttaga
     5281 atatgcgcgc tacatcaatt gggaaaccaa acgacggaag gggaagaatc cgagaccgat
     5341 tttagtgaaa ggaacccatg aaccgattat ttcggaagaa gattatcaaa aagtacaaga
     5401 acgccttgct ttagaaggaa aacaacccaa atggaaccat acaggtgaaa atgtattgac
     5461 aggcttgtta cgttgtccag aatgtggcgc accgatggca gcgagtaatg tcacaaatac
     5521 cctaaaggat ggcacaaaga aacggattcg atattattct tgttcagtct ttcggaataa
     5581 aggagcaagt gtgtgtcatg ccaattcgat tcgtgccgaa caagcggaaa catttgtcgc
     5641 cgaccgatta aaggagatcg ttcagctacc agaagttctt ccccgattgg tggcagcgtt
     5701 aaatgaagaa atagtgcgac aaagccaacc attggaacaa gaactcgtgg tgttactgga
     5761 acgaaaggaa gaattgaaga ctaaaattga aaaatgggaa gctgctttgg aagatagtcc
     5821 tgaattgttt ccgatgttaa aagaccgctt agacgaattg actgaaaaac gacgacagtt
     5881 gcacattcga gaaaatgaaa tcttagggat ctttcaacaa ggagagccga ttcaagtcaa
     5941 agatgtccaa cggatattga ctagtttgga tcgttttctt gcccagagtg agaagaagca
     6001 aatcaaagcc ttgtatcgta cctttataga gaaaataacc tttgatccta accataagga
     6061 gatgttggaa attacgatga aattcacgca tgccgtggta caacaattga atgagcaata
     6121 tcaaatagcc gtatccaaaa caaaggatac ggctattttt gtgttaaaaa caccctttac
     6181 gttaacgatc tagtctaggt tatatcaaac aacgttagag gggcgctaac gcttctctag
     6241 cgatttgaaa tcgttagaga agtagttagg gaggtcctta tcataaatag ggatatttat
     6301 taatgaatat ttgaaatata attgtatata agaattaaaa agagtgggga tagatatgaa
     6361 aaagatgggt aagtgtattt tatgtgaaaa atacactgaa cttactaaag aacatgtacc
     6421 acctaaaaaa tcagggaata ctggaggtaa aaagaccaga actggtaatt tagatgattt
     6481 ccttaagagc gattttacaa aaggtgattt tccgaagggg attaaaagga aacctcaagg
     6541 aaatgtttat tata
//
LOCUS       DAFLVO010000109         6495 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.111, whole genome shotgun sequence.
ACCESSION   DAFLVO010000109 DAFLVO010000000
VERSION     DAFLVO010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6495
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.111"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..542
                     /locus_tag="L1U99_002654"
     CDS             <1..542
                     /locus_tag="L1U99_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1213164.1"
                     /translation="SKKFITACRLDKQKNLPLMIDAIGKLIHEGYECELDIYGEGGLK
                     TELESYINHNGLTEFVHLKEFTNKIHEKMQNAAGFVISSDYEGISNSMLEALAIGVPV
                     IATDCPVGGARMYLGDRNEIGHLVECNNLDKLTDAMRRVLLDRESVVRKAQKGIKLRK
                     ELTSKNISNIWYEYLNQFF"
     gene            585..1985
                     /gene="wzy"
                     /locus_tag="L1U99_002655"
     CDS             585..1985
                     /gene="wzy"
                     /locus_tag="L1U99_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy"
                     /protein_id="HBN1213165.1"
                     /translation="MFSLTLVAFTIFCAFSLNQNYWLNWLGILIYLYAICTWHWRKGD
                     SIFSLYTIFFTLFLLFSYGQCIMWAFGIGTDRGIGTTVVAYGTGIIPSESDMIMVKWY
                     SCISMFVFHIGALLFTRKTTLRKVSWYESGDADADRKFLFKIGCIISIIVVPIVFVSK
                     LLEVRIALVHGYNALYYGDYATQSGYLQIILYLFFPALICLLIGSNFSKVITRFVFII
                     FALYSLLGIMSGDRGSWLYSSIILIWAYTQYKGTFNYKKLIKWLILAVIGIYILNVIT
                     KARDGGGLSKLTLKDFTSVFDSDDSPLVDSFFEMGGTMSIITFFLISGNGIYPFANTY
                     LTSLLGSISTRMLSMFGIKFVLLADWFSQDYLGITWGTGFSMIAEAYVNGGYIGGIVY
                     IFIIGIVIGKILSNSIDNQDIENHPMKMFLAITTANIIMGFPRAASYLIVKNFVYGVL
                     IILLINFFLQQFNKRL"
     gene            2031..3536
                     /locus_tag="L1U99_002656"
     CDS             2031..3536
                     /locus_tag="L1U99_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HBN1213166.1"
                     /translation="MERTARLKKNTIWALVFQITSIVCGMILLRLILTKYGSEVNGMI
                     SSINQFLQIISFLQLGVGAVMQSTLYKPLAEKDNLMISQILASGGKFYRQIAYILLVY
                     VGLLLAVYYVLVPNEFGRSYTMAMIATLSINSFAQYYFGIVNTLLLSADQKIYITYIA
                     QTIAFISNTVACALLISLNTEILMVKLITAIIYLACPIYYRWYVDRNYNIKRNVSYDK
                     EPIPQKWNGVAQHVASVVLDSTDVVVLSIFSNLIYVSIYNVYNLVIYGVKQLFMAMTN
                     GVQALLGELWVRKEIEVLYKTFAWFEWIVHTLTVFIFGCTGILIVPFIQVYTRGVTDA
                     NYNQLSFAALLVTANALHCLRTPYHVMIKAAGKYKETQNSFIIASLLNLGLSLILVKP
                     LGLVGVALGSLISITYHTLWSANYNSKYLLKWPMKKFYKQLFVNILTVVLSFGATSQL
                     KMMSITYLDWIVLAIKCAVIVFICIILVNVLFYRRYVVKIISKIIVKIKKI"
     gene            3833..4924
                     /locus_tag="L1U99_002657"
     CDS             3833..4924
                     /locus_tag="L1U99_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HBN1213167.1"
                     /translation="MLELNTSLSNRTILITGAAGFIGSNLVLELLRTQSSIKIIGIDN
                     MNDYYDVSIKNYRLSEIETEAKNHPGSTWNFIKGSIADKATIDFIFDNYKPSIVVNLA
                     AQAGVRYSITNPDMYIESNIIGFYNILEACRHSYDNGESGVEHLVYASSSSVYGTNKK
                     IPYSTEDKVDNQVSLYAATKKSNESMAHAYSKLYNIPSTGLRFFTVYGPAGRPDMAYF
                     GFTDKLRAGDNIQIFNYGNCKRDFTYIDDIVEGVKRVMQCAPEKIDGEDGLPIPPYHI
                     YNIGNNTPENLLDFVDILQQELIAAGVLPEDYDFESHTELVPMQPGDVPVTYADTSAL
                     ERDFEFKPSTSLRDGLRKFAQWYKSFYEV"
     gene            complement(4992..6470)
                     /locus_tag="L1U99_002658"
     CDS             complement(4992..6470)
                     /locus_tag="L1U99_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HBN1213168.1"
                     /translation="MKKLSQKRLAQIIIDSRKSLKMTQQQLAVATGINRALISRLESL
                     DFIPSIQQLESLAEVLNFEPTDLFINESNKSNRTKHQSKNIAVAGTGYVGLSIATLLA
                     QHNQVTAVDILPEKVKQINNKKSPIQDDYIEKYLAEKNLNLIATTDGAAAYREADFVV
                     IAAPTNYDSKQNYFDTSAVESVIKLVLEVNPKAIMVIKSTVPVGYTESIRKKYNTKNI
                     LFSPEFLRESKALYDNLYPSRIIVGTDQTDKTLREASHTFADLLQEGAIKKDIETLFM
                     GFTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLNTQEIIHGVCLDPRIGTHYNNPS
                     FGYGGYCLPKDTKQLLTNYNDVPQNMISAIVDSNRTRKDFIADRVLELAGTYEANSSW
                     NAEKEKEVVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGATIVIYEPTLENNTTFFG
                     SKVINNLDDFKNISHSIIANRYDSNLDDVKEKVYTRDLFQRD"
BASE COUNT         2114 a          908 c         1163 g         2310 t
ORIGIN      
        1 gtagtaaaaa atttattact gcatgtagat tggataaaca aaaaaatttg cccttaatga
       61 ttgatgcaat aggaaaactt attcatgaag gatatgagtg tgaactggat atttatggag
      121 aagggggatt aaaaaccgag cttgaaagtt atatcaacca taatggatta acagaatttg
      181 ttcatctaaa agaatttaca aataaaatac atgaaaagat gcaaaatgcg gcaggatttg
      241 taatttcttc tgattatgaa ggtatatcta attctatgtt agaagcactg gctattggag
      301 tgccagttat cgctacagat tgtccagtag gtggcgcaag aatgtattta ggtgatagaa
      361 atgaaatagg tcatcttgtt gaatgtaata atctagataa gttaacagat gcaatgcgta
      421 gggtactttt ggatagagaa agtgtggtaa gaaaagcgca aaaaggaatt aaactaagaa
      481 aagaactgac atctaaaaat atttcaaata tatggtacga atatttaaac cagttctttt
      541 aaccaaaagg aggatattgt gtgaaagaaa aaataaatat attgatgttt tcgttaacgt
      601 tagtcgcgtt tacaatattt tgcgcttttt cattaaatca gaactattgg ctaaattggc
      661 ttggaatatt gatttactta tatgcaatct gtacatggca ttggagaaaa ggagattcaa
      721 tattttcatt atacacgatt tttttcactc tttttttatt atttagttat gggcaatgca
      781 ttatgtgggc attcggtatt ggaacagatc gtggaatcgg tacaacagta gtagcttatg
      841 gtacggggat tattcctagt gaatcagata tgataatggt aaaatggtat tcttgtattt
      901 ctatgtttgt atttcacata ggagcactct tatttacgag aaaaaccaca ctaagaaaag
      961 ttagttggta tgaatctgga gatgctgatg ccgatagaaa gtttttattt aaaatagggt
     1021 gtatcatttc tataatagta gtaccgatag tttttgtttc taaattacta gaggtacgta
     1081 tagcattagt ccatggttat aatgcattat attatggtga ttatgctaca caaagtggat
     1141 atttacaaat tattctatat cttttttttc cagccttaat atgtttatta attggtagca
     1201 acttttcaaa agtaataacg agatttgttt ttattatttt tgctttatat tctttattag
     1261 gaattatgtc aggagacaga ggaagttggt tgtatagctc tattatactc atatgggcat
     1321 acactcaata taaaggaacc tttaattata aaaaattaat aaagtggctt attttagctg
     1381 ttataggaat atatattcta aacgtaataa cgaaagcacg tgatggtgga ggactaagta
     1441 aacttacttt aaaagatttt acatctgtat ttgattcaga tgattctcct ttagttgatt
     1501 ctttttttga aatggggggg actatgagta ttataacttt tttcctaata agtggtaatg
     1561 gaatatatcc ctttgctaat acttatttga cctcactctt aggctctata tcaacaagaa
     1621 tgctatcaat gtttggaata aagtttgttt tattagctga ttggttttct caggattatt
     1681 taggaatcac ttgggggact ggattctcaa tgattgcaga agcctatgtc aatggtggat
     1741 acattggggg tatagtctat atttttatta ttggtatagt catcggtaaa atcctttcta
     1801 atagtataga caaccaagat attgaaaatc atcctatgaa gatgtttttg gctataacta
     1861 cagcaaatat tataatgggt tttcctagag ctgcttcata tttaattgtg aaaaattttg
     1921 tgtatggtgt tttaattata ttgttgataa actttttcct acagcaattt aataaacgtc
     1981 tttaatattt aagcttaata aaaagataaa acaagtcagg agttgcaaaa atggaaagaa
     2041 ctgctcggct caaaaaaaac actatttggg ctctggtgtt tcaaataact tctattgtct
     2101 gtggtatgat cttgctacgt ttgatattaa caaagtacgg atccgaggtt aatggaatga
     2161 ttagctctat taaccaattt ctacaaatta tttctttttt acaattagga gtaggcgctg
     2221 taatgcaatc aactctatac aaaccactag cagaaaagga taatttaatg ataagtcaaa
     2281 tcttagcttc tggagggaag ttttatcggc aaattgcata tattctacta gtatacgtgg
     2341 gtttgttact tgcagtctat tatgttctcg ttcctaatga atttgggaga tcatatacaa
     2401 tggcaatgat tgcaacatta agtattaatt catttgctca atattatttt ggtattgtta
     2461 atactttgtt attaagtgct gaccagaaaa tttatattac gtatattgca cagacaatag
     2521 catttatttc taatacagtt gcatgtgctt tattaattag tctgaacaca gagatcctta
     2581 tggtaaaact tattactgct ataatttatc ttgcttgtcc aatatattat agatggtatg
     2641 tggatcgaaa ctataatata aagaggaatg tgtcatatga taaggaaccg atccctcaaa
     2701 aatggaatgg ggttgcacaa cacgtagctt ctgttgtact agatagtact gatgttgtag
     2761 tgttatctat attttctaac ctgatatatg tatctatata taatgtgtac aatttagtaa
     2821 tatacggagt aaaacagcta ttcatggcta tgacaaatgg cgttcaggcc ttactagggg
     2881 aactttgggt cagaaaagaa atagaagttc tttacaaaac atttgcatgg ttcgaatgga
     2941 ttgtacatac tttgacagtt tttatttttg gctgtaccgg tatactaatc gttccattta
     3001 ttcaagtata tacaagagga gtaacagatg ctaattataa tcaattatca ttcgcagctt
     3061 tacttgtaac tgctaacgca cttcactgtc tgcgtacacc ttatcatgta atgataaaag
     3121 cagctggtaa atataaagaa actcaaaata gttttataat tgcttctttg ttaaatttag
     3181 gtttatcatt aattttggtt aaaccactag ggctagttgg agtagcatta ggatctctaa
     3241 tttcaatcac atatcataca ctttggagtg caaattataa ttcaaaatat ttgcttaaat
     3301 ggccgatgaa aaaattctat aaacagttat ttgtaaacat cttaactgta gttctttctt
     3361 ttggggcgac atcacaattg aaaatgatgt caatcacata tttggattgg attgttctcg
     3421 caattaaatg tgcagttatt gtatttatat gtataatcct agttaatgtt ttattttata
     3481 gaagatatgt agtaaaaata attagtaaaa tcatcgtaaa aataaagaaa atttaataca
     3541 caataaatgt tttaataaac ttaataaaat tatatttgcc aaaattagac acatatatta
     3601 aattttttct tttaaggtta cttatgtgat caagaataat ttctattcgt tttagaataa
     3661 gttaatagat aatagaaaga agtgggttgc ttagcaattt cctatctgta taattattct
     3721 actacgtgca aagattagaa tgataaaagt gacaatagat aagtctaaat aagatttttt
     3781 aatatataac aaatatgtat tcataagaaa aaaagaaagt gagtgctaaa aaatgctgga
     3841 attaaacacg tccttatcaa atagaacaat attaataact ggcgcagccg gttttattgg
     3901 atcaaatttg gttcttgagt tattacgtac tcagtcatca ataaaaatca ttggcattga
     3961 caatatgaat gattactatg atgtctctat taagaactat agattatcag agatagaaac
     4021 ggaggcaaag aaccatccag gatctacttg gaattttatc aaaggttcta ttgctgataa
     4081 agcaacaatt gatttcatct ttgataatta taaaccaagt atcgtggtga atttagcagc
     4141 tcaggcagga gtccgttatt caattactaa tccagatatg tatatcgaat ctaacataat
     4201 aggattctat aatattcttg aagcttgtcg tcattcatat gataatggag aatctggtgt
     4261 ggaacattta gtgtatgcct catcgtcttc cgtttatggt actaataaga aaattcctta
     4321 ttctacagag gataaagtag acaatcaagt atcgttgtat gcagcaacta agaaaagtaa
     4381 tgaatcaatg gcacatgcat attctaaact ttacaatatt ccgtctacag ggttacgttt
     4441 ctttacagta tatggtcctg ctgggcgtcc agatatggct tattttggtt ttactgataa
     4501 acttcgtgct ggtgataata tccaaatatt caattatggg aattgcaagc gtgactttac
     4561 ctatatagat gatattgttg aaggagtaaa gagggttatg cagtgcgctc cagagaaaat
     4621 tgatggggaa gatgggctac caatcccacc atatcatatt tataatattg gtaacaatac
     4681 gccggaaaac ctactagatt ttgtagatat tctacaacaa gagctaattg cagcaggggt
     4741 gctaccagaa gattacgact ttgaatctca taccgaacta gttccaatgc aaccaggaga
     4801 tgtgccagtt acttatgcag atactagtgc gttagaacga gattttgaat ttaaaccaag
     4861 tacaagtttg cgtgacgggc ttcgtaaatt tgcgcagtgg tataagtctt tttatgaagt
     4921 ataattgtat ttttttactt ataaaagttt atagaaacac ctcagacact acaaatctga
     4981 ggtgttattt tttaatctcg ttgaaataaa tctctggtat atactttttc ttttacatca
     5041 tcaagattac tatcgtaacg attagcaata atactgtgac tgatattttt aaaatcatct
     5101 aaattattta ttacttttga accaaaaaat gtagtgttat tttcaagtgt tggttcataa
     5161 attacaatag ttgccccctt tgctttaatt cgcttcataa ctccttgaat agatgactga
     5221 cggaagttgt ctgaattact cttcattgta agacggtata cacctatgac tacctctttt
     5281 tctttttctg cattccacga actgttagcc tcatacgtgc cagcaagttc taacactcga
     5341 tctgctataa agtcttttct tgtacgatta ctatcgacaa ttgcacttat catattctga
     5401 ggaacatcgt tatagttagt gagaagttgt tttgtatctt tcggtaaaca atagcctcca
     5461 tatccaaaag atggattatt ataatgtgtg ccaattcttg gatctaagca aaccccgtga
     5521 atgatttctt gtgtatttag tcctttcatt tctgcataag tatccagctc attgaagtaa
     5581 gatactcgaa gtgcaaggta agtattagcg aataatttaa ctgcttcagc ttctgtgaat
     5641 cccatgaaaa gagtttcgat atcttttttg attgctcctt cttggagtaa atctgcaaaa
     5701 gtgtgagagg cttctcgtaa agttttgtca gtttggtccg tgccgacaat aattcgcgaa
     5761 ggatatagat tgtcatataa tgccttagat tctctgagaa attctgggct gaatagaata
     5821 tttttagtat tgtatttttt acgaatactt tcggtatagc ctacgggtac cgtcgacttg
     5881 atgaccatta ttgcctttgg attgacttct aacaccaatt tgattactga ctctacagca
     5941 gaagtatcaa aataattttg tttactatca taatttgttg gagcagcaat gacaacaaaa
     6001 tcggcttctc tataggcggc tgcaccatca gtcgttgcaa ttaaattaag atttttttca
     6061 gctagatatt tttcaatgta atcgtcttgt attggagatt tcttattgtt aatttgtttt
     6121 actttttcag gaagaatgtc tactgctgtt acctgattgt gctgggcaag aagagtagca
     6181 atggaaagac ctacgtaacc agtaccggct acagcaatat tcttcgactg atgttttgtt
     6241 ctgtttgatt tatttgattc atttataaat agatctgttg gttcaaaatt tagaacttct
     6301 gctaatgatt ctaattgttg tattgacggg ataaaatcga gagattctaa tcgactaatt
     6361 aaggcacggt tgataccagt agctactgca agttgttgtt gtgtcatttt cagagatttt
     6421 ctagaatcaa taatgatttg agctaaacgt ttttgagata actttttcat gatgcactcc
     6481 tttttttgtt gctaa
//
LOCUS       DAFLVO010000110         6418 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.112, whole genome shotgun sequence.
ACCESSION   DAFLVO010000110 DAFLVO010000000
VERSION     DAFLVO010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6418
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.112"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            145..483
                     /locus_tag="L1U99_002659"
     CDS             145..483
                     /locus_tag="L1U99_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213169.1"
                     /translation="MFDSIKNLVSGMTPDMKTLVQVVLYFLAFVFSLKPGFTAMKFFG
                     DAKWGDGLKYVGAIIAIFIIPVITTVMLYTMGTKTGNDLNQKANIISALIPVVGIYLV
                     SKFPKNELLG"
     gene            593..814
                     /locus_tag="L1U99_002660"
     CDS             593..814
                     /locus_tag="L1U99_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213170.1"
                     /translation="MVFDREKMLAHANEVLMSSLKGTELAKIMNMNVNQFYDYRNGSK
                     KIEKARLETLIKFEKAYVYMLDKQKRTID"
     gene            834..2990
                     /locus_tag="L1U99_002661"
     CDS             834..2990
                     /locus_tag="L1U99_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213171.1"
                     /translation="MAKFKDITESINYVAETVPVVALSLKPQLLEVYKKEEKEAKAKK
                     AKAKVWKEFDALLTKDLPKKNYMVIEDVQKLNSEGVIDEDDAILDSEKYVVLLKSSLN
                     YVADLPEKFKEKLLAGVRFMDSSGQLLVIPDDPNVFESEVEEATDFYSAVEQLEVATN
                     GLERIAETFNSSEEVEFEAVAENVPDEKEALFVDDNKPTEAENQEVSIEETQIQTETY
                     QQPKIDEKPESQSDKENYVYEAEKITSESDVPKNLDADFLEKNFEQIIADKFQPVVLD
                     EINDPVDLNEEMLSIPELKPLLFLAKESMNARISIANNKINSELNKTKEQLILKGKQM
                     LADELLRIEEATSLNGQNQFTNTLSVAKESYEAEASKIDDLVMEKSNIIRKDYDMAKQ
                     AYLDAELKKLEQRYDAEHLPEVKQQEDEYRKATEESLDQQYQEAIESIKNDALKQSQE
                     AKEVVVERIINSLKPEIEKSLTDVQEKTLEIVEKTKSENEAEFHDTKEKTTDVVVKYF
                     ANKEEVEKQVANNTKELETKLVEQQKTIEEYKDRMKEVKDLAEGYKLNSEKLAEQSEA
                     LREDLSRSRSDLAQMAEKTKSLAVATENQSSSKRDFTSKKMATIISVAAMACGTILGS
                     SYFISHNNQQAQAQTQTSISRVENSIGTNTNSASTNSSYEATPTTEFKVGKDVVISID
                     GKTTKAEVISIDGEKAVVKTPDGNQYKIQAHLSDNN"
     gene            3002..3235
                     /locus_tag="L1U99_002662"
     CDS             3002..3235
                     /locus_tag="L1U99_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBN1213172.1"
                     /translation="MREEKIVYPVIQNNQENMTSSQHLQEAQLVYQVNELPQTNETMS
                     KSISLIGLLIVAIVITVGVYRKLNVKGSISDGR"
     gene            3225..4091
                     /locus_tag="L1U99_002663"
     CDS             3225..4091
                     /locus_tag="L1U99_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213173.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVEWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLKFIFVPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNSARVSMGKKKPFRGTEILKVKQDGTIVYRDGSVALMFNLDGATSLTAFP
                     EEVMAQESKSIQYQNTRDRSLAEIKITSSQPQNTERQTRNMKIQKRNARSNKAVFDII
                     DQQERFVSEYIDGVKTTVIQYLILKSQSKMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSDIYALK"
     gene            4106..6076
                     /locus_tag="L1U99_002664"
     CDS             4106..6076
                     /locus_tag="L1U99_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213174.1"
                     /translation="MEIMGRSQLLNFKKKRKTKKEQKTRNSKVVNNTFVSDLTSLVGY
                     QFTPSYIRTGKRWGTIVKLVNTYGMNRNYGFGWMVKAIPEVRVEGVKAYLIEADKPVS
                     QKDQQEIMHENVGGSTNSYENNLEGKNSDAEISKTVMRIMDLNTASLLDSMANKIIDW
                     KLEILLVSDSPNKISEQLIKLQRLYDEKMYGLKLMSYGGDQRDLFDRLLSEPIGNVYE
                     YTSMSSDFAGNDHAIRKGLDDANGWAIGTMSTSYASGVAFMALDDSFTSKVLVASHKN
                     ATIKGYDEKISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGRTFVAKPSLNS
                     VIEKVNLAEEGLNSLELFGNQKDIGDLYRRNLDKLTQIFYLLAGRTLDSATRVLLKKE
                     LGNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEVDRI
                     IVLKDTLRTALDSFSRMFNQRTTLKEIGKSDKLQFYYNLGDLRAETNVMEAQFLNTFD
                     FITSQAKKDDIVMIHGFDKLSIETVGLIKKRLTMLEEDGIRLAFLFDTIGSGEDNEYK
                     EDIETADIFNTDGKIYQSFESDFNYTIIGKMTSGELMKYEKKVAPARKGEDDQKLSVD
                     LRQYLTTGRSNKFQIRRPVDLTNNFVIGEFIL"
     gene            6243..>6418
                     /locus_tag="L1U99_002665"
     CDS             6243..>6418
                     /locus_tag="L1U99_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213175.1"
                     /translation="MKPNIKILDRIFLGRDTEVILIQHEEGFEVSIGIQKLQKPHYCN
                     QLYKNFTDEEKARV"
BASE COUNT         2469 a          879 c         1252 g         1818 t
ORIGIN      
        1 catcgaaaat ttatgttatt atgataacat aaagatgtaa atatcgagac gtctttttct
       61 tagttagatc attgacaagt gaacaaataa gatttgtcga tgatataatt aacttattaa
      121 aaatattaaa aaggaggttt ttatatgttc gattctatta aaaatttggt tagcggaatg
      181 acgcctgata tgaaaacttt agtacaagtt gttttgtatt tcttggcatt cgttttttcg
      241 ttgaaaccag gattcactgc aatgaaattt tttggtgatg caaaatgggg agatggatta
      301 aaatatgttg gggcgattat tgcaatcttt attattcctg taattacaac cgttatgctt
      361 tacacaatgg gtactaaaac aggtaatgat ttgaaccaaa aagctaatat catatcagca
      421 cttattccag ttgttggtat ctatctagtt tcaaaatttc caaaaaatga actgttaggt
      481 taaaagtgaa ttgaacaaat ttggataata tgccgatttg ttcaatttac tttttaccaa
      541 aaaactacgc tccaagcgta gtttagaagt gagggaagaa agtaaatgta agatggtttt
      601 tgatagagaa aaaatgttag ctcacgccaa cgaagtatta atgagcagtc tgaaaggtac
      661 cgaactggca aagataatga atatgaatgt taaccagttc tatgattatc gaaatgggag
      721 taaaaagatt gaaaaagcca gacttgaaac gcttattaaa ttcgaaaaag catatgtata
      781 tatgctagat aaacagaaaa gaactattga ctgaaaaaag gagttttaca ataatggcaa
      841 aattcaaaga tattaccgaa tctattaatt atgtggcaga aacagttcct gtagttgcac
      901 tctctttgaa gccacaatta ctcgaagtgt acaaaaaaga agaaaaagaa gcgaaggcaa
      961 aaaaagctaa agcaaaggta tggaaagaat tcgatgcgtt gctgaccaaa gatttaccaa
     1021 agaaaaatta tatggtaatt gaagatgtac aaaagctcaa cagtgaggga gttatagatg
     1081 aggatgatgc tattctcgat tctgagaagt atgtcgttct attgaagtca agtttgaatt
     1141 atgtagctga tctaccagaa aaatttaaag agaagctatt agcaggtgtc cgttttatgg
     1201 atagtagtgg tcaattatta gttattccgg atgatcctaa tgtgtttgaa tcagaagttg
     1261 aagaagctac agacttctat agcgcagtag agcaattaga agtagctact aatggattag
     1321 aacgaattgc tgagaccttc aactcttctg aagaagttga atttgaagcc gtagcagaaa
     1381 atgtaccaga tgaaaaagaa gctctttttg tggatgataa caaaccaacc gaagcagaaa
     1441 accaagaagt aagcatagaa gaaacacaaa tacaaacaga aacctaccaa caaccaaaaa
     1501 ttgatgaaaa acccgaatcc caaagtgaca aagaaaatta tgtttatgaa gctgaaaaaa
     1561 tcacatctga aagtgatgta ccgaaaaact tagatgctga ttttttagaa aaaaattttg
     1621 aacagatcat tgctgacaaa tttcaacctg tagttttaga tgagattaat gaccctgtcg
     1681 atttaaacga ggagatgcta tccatacctg agttgaaacc attgctgttt ttagctaaag
     1741 agagtatgaa cgctcgcatc tctattgcta ataataaaat caacagtgaa ttaaataaga
     1801 cgaaggagca attgatcctc aaaggaaagc aaatgttagc tgatgagctt ttgcggatag
     1861 aggaagcaac ctcattaaat ggtcaaaatc agtttacaaa tacactatcg gttgctaaag
     1921 agagctacga agcagaagca tctaaaattg atgatttagt gatggaaaaa tccaatatca
     1981 ttcgtaaaga ttatgatatg gcgaaacagg cttatttgga tgctgaacta aagaaactag
     2041 agcaacggta tgatgctgag catttaccag aagttaaaca acaagaagat gaatatagaa
     2101 aagcaactga agaaagtctt gatcaacagt accaagaagc aattgaatct attaaaaacg
     2161 atgcattgaa acaaagccaa gaagcaaaag aagttgtggt ggaacgaatt atcaattcat
     2221 tgaaaccaga aattgaaaaa tcattaacag acgtgcaaga aaaaacttta gagattgtcg
     2281 aaaaaacaaa gtcagaaaat gaagctgagt tccatgatac aaaagagaaa acaacagatg
     2341 tggttgtcaa atattttgcg aacaaagaag aagttgaaaa gcaggtagct aacaacacga
     2401 aagaattaga aacaaaactt gtagagcaac aaaaaactat cgaagaatat aaagatcgaa
     2461 tgaaagaggt caaagattta gcagagggtt ataaattaaa tagcgaaaag ttggcagaac
     2521 aaagtgaagc tttaagagaa gacttatctc gttcccgaag tgatctagct caaatggcag
     2581 aaaaaacgaa atcattagca gttgctacag aaaatcaatc aagttcaaaa cgtgatttta
     2641 caagtaaaaa gatggctact atcatttctg tcgctgcaat ggcttgcgga acgatcttgg
     2701 gatcgtccta ctttattagt cataataatc aacaagcaca ggctcaaact caaacatcta
     2761 tttcgagagt ggaaaattcg attgggacaa atacgaactc tgcttcaaca aatagtagct
     2821 atgaagcaac accaactaca gagttcaaag ttgggaaaga tgttgtcatc agtattgatg
     2881 ggaaaacaac taaggctgaa gtgatttcta ttgatggaga aaaagcagtt gtgaaaactc
     2941 cagacggaaa tcagtacaaa attcaagctc acttatctga taataactaa ggagggctat
     3001 tatgcgagaa gaaaaaatag tttatccagt aattcaaaac aatcaagaaa acatgacctc
     3061 ttctcagcac ttacaggaag cacagctcgt gtatcaggta aatgaactac cacaaacgaa
     3121 cgagacaatg agcaagtcaa tatctttaat tggcttgctt attgttgcaa tagtgataac
     3181 tgtaggtgtt taccgtaagt tgaacgtgaa aggaagtatt tctgatggca gataactcaa
     3241 actatggatt taaacataac ttacatcaaa aaccttctga aacaattgtc agagttgaat
     3301 ggcttgaaaa gcatgtcaat agcacctatt ctgttacagc aaaaagatta attgtatcag
     3361 ctatagttgt tgcagtcgtt gttcttggat caattgttta cttagtttct gatacgatta
     3421 aactgaaatt tatttttgtt ccaacgttat taatgataat tggatttctt attctaatta
     3481 gccagtatat gtttattgat ccatctagtg gttcattgat ttctggttct attagactgt
     3541 tcaaatcagt agttaattca gcaagagtat ctatggggaa aaagaaacca tttcgaggca
     3601 cagagatttt aaaagtgaaa caagatggaa caatcgtata tcgagatggg agtgtagcat
     3661 taatgttcaa tctagatggg gctacatcac taaccgcttt tccagaagaa gttatggctc
     3721 aggaatcgaa atcaatacaa tatcaaaata ccagagatcg ttccttagct gaaatcaaaa
     3781 tcacttcatc tcaacctcag aatacggaaa gacaaactcg aaatatgaaa atacaaaaac
     3841 gaaatgcaag gagtaacaaa gcagtctttg acataataga tcagcaagaa cgatttgtat
     3901 cagaatatat tgatggtgtg aaaacaacag taatccaata tcttatcttg aaatctcaat
     3961 ctaagatggt attggatgaa ggtgtggaac gtttagaaaa ctatacgagt agaggacttt
     4021 attatagtgt cactcagttg tcagctaaac aaacaaaaga aatattatct gatatttatg
     4081 cactgaaata gaggtgagag attaaatgga aattatgggt agatcacaac tattaaattt
     4141 caaaaaaaag agaaaaacta aaaaagaaca aaaaactaga aattcaaagg tagtgaataa
     4201 tacctttgtt agtgatttaa catctttagt tggttatcaa tttacaccat cttacattag
     4261 gacaggtaag cggtggggaa caattgtgaa attagtgaat acttatggaa tgaatagaaa
     4321 ttatggattt ggttggatgg ttaaagctat tcctgaagtg agagtagaag gggtaaaagc
     4381 ctatctaatt gaagcagata agccagtgtc acaaaaagat caacaagaaa taatgcacga
     4441 gaatgttggg ggatcaacga atagttatga aaataattta gaaggaaaaa attcagatgc
     4501 tgaaattagc aaaactgtta tgcggattat ggatttgaat acagcatctt tactagacag
     4561 catggcaaat aaaattattg attggaagct agaaatccta ttagtatccg attctcctaa
     4621 taaaatcagc gaacagctaa ttaaactcca acggttgtat gatgaaaaaa tgtatggatt
     4681 aaagcttatg tcatatggag gagatcaacg tgatctgttt gatagacttt taagtgaacc
     4741 aatcgggaat gtctatgagt atacgtctat gagttcggat tttgcaggaa atgatcatgc
     4801 aattcgcaaa ggtttagatg atgcgaatgg atgggctatc ggcactatgt ctactagcta
     4861 cgcaagtggt gtagctttta tggcactgga tgattctttt acaagtaaag ttttagtggc
     4921 atcacacaaa aacgctacaa ttaaaggcta tgatgaaaaa atctcagcat catcactttg
     4981 ggggcaattg attgctaata atgcaatggc aaatcataaa cgaacttttc atattgtctt
     5041 aaataaattt gattactttg gtgatccaac tggtagaaca tttgttgcca aaccttcgtt
     5101 aaacagtgta atagaaaagg ttaatttggc tgaagaaggt cttaactctt tggagctttt
     5161 tggtaatcaa aaggacattg gtgatttata tagacggaat ctcgataaac taactcagat
     5221 tttttatttg ttagcaggca gaacattaga ttctgcaact agagttttat tgaaaaaaga
     5281 attaggtaac ttttatataa gtcagaaact ttgggatatt aattatgaag aacgttcaaa
     5341 acttttggtg aacagtagtg atacaatgcc agttcttggg gattttatta gctatttgac
     5401 taatgctgaa acaaaagcca aaaaatctgg tactgaaaaa gaagtcgatc gtattattgt
     5461 attaaaagac acattgagaa cagcattaga cagcttctct aggatgttta atcaaagaac
     5521 gacactgaaa gaaatcggta aaagtgacaa attacagttt tactataact taggtgatct
     5581 aagagcagaa accaatgtta tggaagctca atttttaaat acctttgatt tcatcacatc
     5641 acaagcaaaa aaagatgata ttgttatgat tcacggcttc gataagttat ctattgaaac
     5701 cgttgggcta attaaaaaaa gattaacaat gcttgaagaa gatggaattc gtcttgcctt
     5761 tctatttgat acaatcggtt caggagaaga caatgaatac aaagaagata ttgaaacagc
     5821 tgatatattc aatacagatg gaaaaattta ccaaagtttt gaaagtgatt ttaattacac
     5881 tatcattgga aagatgacca gtggagagtt aatgaagtat gaaaaaaaag ttgctcctgc
     5941 tagaaaagga gaagatgatc aaaaactttc tgttgatttg agacagtatt tgacaacagg
     6001 aagaagtaat aaatttcaga tcaggagacc agtggatctg actaataatt ttgttattgg
     6061 agagtttatt ctttaagttt tatctttgat tttgagtgta taaggaaagg ataagaaaaa
     6121 acatgtatat ttgagactaa aaacagtctt agagaacatg gtacgttttg tgaaaagaga
     6181 actatagaaa tttcataaag tgaaacctta ctgagtgaaa taattatagt ggaggttaaa
     6241 taatgaaacc aaacataaaa attttagatc gaatatttct aggtagagac acagaagtaa
     6301 tcctaattca acatgaagaa ggatttgaag ttagtatagg tattcagaaa cttcaaaaac
     6361 ctcattattg taatcagttg tataaaaact ttactgatga agaaaaagcg agagtttt
//
LOCUS       DAFLVO010000111         6387 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.113, whole genome shotgun sequence.
ACCESSION   DAFLVO010000111 DAFLVO010000000
VERSION     DAFLVO010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.113"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            330..1175
                     /locus_tag="L1U99_002666"
     CDS             330..1175
                     /locus_tag="L1U99_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1213176.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="L1U99_002667"
     CDS             1456..2676
                     /locus_tag="L1U99_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HBN1213177.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="L1U99_002668"
     CDS             2673..5393
                     /locus_tag="L1U99_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1213178.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="L1U99_002669"
     CDS             5377..6321
                     /locus_tag="L1U99_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBN1213179.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2379 a          987 c         1231 g         1790 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttc
//
LOCUS       DAFLVO010000112         6365 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.114, whole genome shotgun sequence.
ACCESSION   DAFLVO010000112 DAFLVO010000000
VERSION     DAFLVO010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6365
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.114"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            31..255
                     /locus_tag="L1U99_002670"
     CDS             31..255
                     /locus_tag="L1U99_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213180.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLNLFNRIVGA"
     gene            268..768
                     /locus_tag="L1U99_002671"
     CDS             268..768
                     /locus_tag="L1U99_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBN1213181.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            865..2712
                     /locus_tag="L1U99_002672"
     CDS             865..2712
                     /locus_tag="L1U99_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBN1213182.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            2715..3611
                     /locus_tag="L1U99_002673"
     CDS             2715..3611
                     /locus_tag="L1U99_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1213183.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            3661..4050
                     /locus_tag="L1U99_002674"
     CDS             3661..4050
                     /locus_tag="L1U99_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBN1213184.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            4037..>6365
                     /locus_tag="L1U99_002675"
     CDS             4037..>6365
                     /locus_tag="L1U99_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1213185.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         2145 a          943 c         1363 g         1914 t
ORIGIN      
        1 gaatgggggg aaaagtttga gatatttata atatcaggaa cttacctatc catatatcaa
       61 tggtttttaa ccaatgctca atctttagtc ttactagcga ttgtggtcat tggtttgttt
      121 ttaggattta aacgcgagtt ttccaaactg attggcttct tggtgattgc tttgattgcg
      181 gtaggtctgg tctttaatgc ttctggtgtg aaggatgtct tactcaattt gtttaaccga
      241 attgtcggtg cctgaggggg aatcacaatg gaacagatac gtgtttatat tgcgaacctt
      301 ggaaaataca atgaaggtga gttggtgggg gcatggttta ccccacccgt cgattttgat
      361 gaagtgaaag aacggattgg attaaatgac gaatatgaag agtacgcaat tcatgattat
      421 gaactgcctt ttgagattga tgagtataca ccaattgagg aaattaatcg gttgtgtggt
      481 ttagcggaag agcttaaagg aacgccaatt ggtgaggtcg cttcagagat tcaacatgcc
      541 ttcttcaatt ctttcgagga aatggtagag catgtggatg atatcatcta ttatcccgat
      601 tgtaatgaca tgagtgatgt agcgtattac ttgattgtag aagctggtga tttaggcgaa
      661 gtaccagaac acttgaagac gtatattgat tttgatgcgt gtggtcgaga cttggagatt
      721 ggcgggaatt atttggttac gagtcgaggg gtttttgaac taatgtaaat catttgttag
      781 aattgaccag aaatttctat cgtactttta cttttctatt tgatatactg aaatagaaaa
      841 tatttgttga taggggtgtt actaatggtt ggcaataagt ggtacaaatg tgatcttcat
      901 attcattcaa ctgcgagtca gtgctttcag gataaaaagg ttactgctaa ggaatgggta
      961 gaagaatgtt taaacaaagg actcgattgt gttgcattaa ctgatcacaa tacaggggaa
     1021 aatattgatg aatataagaa agtggctatc gaaaatggct tagatttttt tcctggagtg
     1081 gaattaacgt gtggagaaaa tggaactcat ttactagtcc tatttgataa aagtgcatgt
     1141 acaaatgata tctctgattt cttaaccaag atgggtataa aaagagagga ttgggccagc
     1201 gctgcagctt gctcaatgaa atcagtttta gaagttattg attttgctga gcacgagggc
     1261 ttgctcgtta ttcctgcaca tatagatgag tttaatggaa tttcttcagc aaaatttgga
     1321 aatctaggaa agatatttga atcagaaaat atatatgcag tacagacggt tcaaaaagaa
     1381 ttttttgaaa atcgctcaca aatgattccc tcatctaagc gtgacactat ctatgatagt
     1441 gtgaatgcca gatatgatgg tagagttgga aaagatactt tggaatcttg gtataaatca
     1501 gttgttgagg cagaaaaaaa taatatgaca tttcttagct tttctgataa cccacactcg
     1561 aaaggaaatt caaaacatgg actttgggga ataggcacaa gatattccta tataaaaatg
     1621 aaggacgaac ctgacttggg atcacttcgc gatgctttaa tgctaggcga aactcgagtt
     1681 cattctgatt tttctaattt ctccattaat gaaaatgaag ttttattgga aaaattaagc
     1741 ttttctggga ccactcttag cacaaaagaa gttgtagtcg aattcagcga taatttaact
     1801 tcaattattg gaggaagagg aacaggcaaa tcttgtatta caagattctt ggtctatgtc
     1861 cttggaaagg aagcagaact tgatcaattt tctgaaatac aaagtgatta tcagaacttt
     1921 gcacaaattg aacataatgg ctctggaata tttttgaagg atacaattgt gaaactgaat
     1981 attttctata aggggacaaa atatcaaata ataagaacac aggatagaca ttctatttat
     2041 gaatttacac aagagaatgg tctggttgaa aaagaaacag aacggttgag aatgatttcc
     2101 gataaggtga gtatatactc tcaaaaacaa atttatgaaa tttcaaaaaa tcaaactagt
     2161 atactagaat tactagatgg atataactct gatttgattt cagagtataa aaatgagatt
     2221 gaaacatgtg taaacgaaat aagaaaatta aattgggata ttgtttctgt gaaaaaagaa
     2281 atacaagata aggcgaaggt agagcttgaa attgaagatt taaaaaaaca agtagaaaag
     2341 ctatctcata agagttataa agatgtttat gatgagtatt caaaagagac agatatttat
     2401 agggaactga aacgtgatgt ggaggcactt aaggaaattc ccaaaaatct aactgatagt
     2461 gttgacaaaa ttgactttgg caatggtata aaagttacag acgaaattga tgaacaccgc
     2521 ggagaattga ttaagaattt agtgaccaat cgggctaaga ttcaaacaat aattaatgaa
     2581 atgtcagatg aaattgatag ttatagagca gagctgaata aatcagattg gaaagttaac
     2641 tataatgagg tttcaaagag gtatcaaaga ggtatcaaaa acttagtgaa gagttatctc
     2701 aagatgaatt aaaaatgtta caaaaccttg attctttata tcaatcttta tcaaaaactg
     2761 aagagcgatt ggaagaaatt attcaacaag aaataaagct taaagattac caagttgagg
     2821 ttgactcagc aatgtcaaga atgaataaat catatcaaaa tctctattct gagagaagta
     2881 gttcctcgcg cgaaattttt tctgatatta caggaataga ggctactatt caaccaaata
     2941 gggatttcaa taattatgtt aaagagctca gagcttgtat taataaggag gacacttttg
     3001 acagtgagtt tggatctctt attgataagc tgacaaaaaa ttccattact aatcaagata
     3061 tatataatga catacttgat ataagagtta gtggggaaag tagtattttt tcagataaaa
     3121 aattaatcaa ttctataaga aaattgaatg atgcacaagt tcttgaatta caaaccctta
     3181 agccaaatga tttagtagtt atccgacttg aactaaatgg aaaaaaagtt agtttatcga
     3241 atgctagtgc tggtcaaaag acatctgcaa ttctttctat gattttggcg tatggaaatt
     3301 caccactcat attggatcag cctgaagatg atttggatag tcaattaatt aataacttaa
     3361 tcgtaagaag tatcattaca aaaaaggaaa acagacaaat tttaattgta actcataatg
     3421 caaatatccc agttaatggt gattcagaat ggttgattag catgggagat tcaaaagaaa
     3481 tatcggctga tcagtgcggg tcggtagatg aacccaatat caagccaaga atatgtactg
     3541 tgatggaagg tggcgaggat gcttttacaa atagagcgaa acgctatggt tttaaacaaa
     3601 ttgtagaata acactagagg gtgagacata ttattatgtc cgcccttttt aggaggaaaa
     3661 atgaaaaaaa taaaaagcta taccagtatc tgggcagttg aaaaagtcat ttacgcaatc
     3721 aatgattttc agttgccttt tcctgtgact tttaaccaaa tggcttggtt cgttttatct
     3781 ttactgtttg tcatcgtatt tgcccatgtg cctccactat ctatgataga ggaggtcttt
     3841 ttaaaatact taggcatacc ggtggctgtc acttggttta tgtcgcaaaa gacgtttgat
     3901 ggcaagaaac cactgggatt tttacgatcc tttatcagct atcacttgcg atttaaggtg
     3961 acttttgcag gaaagaaagt caaagaacag aagaaacgat gggatgaacc cagtactctt
     4021 gtaaggagtg tgaactatgt atccgattaa gtatattgaa aataatctcg tctttaacca
     4081 agaaggcgag tgttttgcct actatgaatt agtgccttac aattactcct ttttgtcacc
     4141 cgaacagaaa tttcaagtgc atgataactt tcgccaacta attgcgcaaa atcgtgaagg
     4201 caagatccat gcgttacaaa ttgccacaga aagtagtatt cgcgccacac aagaacgatc
     4261 aaaaaaagaa attaccggta gactcaaaga agtagcgaaa caacgaattg atatacagac
     4321 agatgcatta gtatccatga ttggcgatag tcagattgat tatcgctttt ttattggctt
     4381 taaactaatt gcgacagatg aagaagtcaa tctaaagagt ctcaagaaat ctttcttttc
     4441 tgggcttcaa gaatttgtct atggagtgaa tcatcatttg atgggcgatt ttgtttcctt
     4501 atccaatgaa gaaattcgct gctattctaa gcttgaaaaa ttaatggaaa gcaaattggc
     4561 tcgaagattt aaagtcaggc gagtcacacc gagtgacctg acgtatttga ttgaacatat
     4621 ttatggcgaa aaagggatac cgtttgaaga atacgaattt cagctaccaa agaaaaagct
     4681 aaaatcagaa acactggtga aacgttatga cttattacgt ccaaatcgtt gtttaattga
     4741 agaaaaacca aggtgcttac ggatggaaca tgagaatcat gagtcgtacg tagcgtattt
     4801 aacaattaat acaattgtgg gggagatgga atttccttcc tcagaacttt tctattacca
     4861 gcaacaacaa tttacattcc caatcgacac aagtatgaat gtagagattg tgacgaataa
     4921 aaaggcttta gctaccgttc gtaataagaa aaaagaactg aaagatttag acaatcatgc
     4981 ttaccaatct gacaatgaaa cgaattccaa tgtcttagat gctttggatt ccgtggatga
     5041 attggaaacc accttggatc agtcaaaaga atctatgtac aaactgagtt atgtggttcg
     5101 agtgagtgcc gaatcagtgg atgaactaaa gcgacgctgt gatgaagtgc tcgattttta
     5161 tgatgatacc aatgtaaaac tagtccggcc ctttggcgat atgatggggc tacatgaaga
     5221 attcttaccc tcaagtaaac gatatatgaa cgactatatt cagtatgtta cgtctgattt
     5281 tttggcgggg cttggttttg gggctactca gatgctagga gaattagaag ggatttactt
     5341 tggctacaat gtggatacag gtcgtaatgt ttacctgaaa ccggcattgg cttcacaagg
     5401 agtcaagggt tcagtaacca atgcgctggc cgccgctttc ctgggttctc ttggtggagg
     5461 taaatccttt agtaacaatc tcttagtcta ctatgctgtt ttgttcggtg gtcaagctgt
     5521 gattgtcgat ccaaaagggg agcgaggagg gtggaaagaa accttgccag aaattgcgga
     5581 tgaaatcagt atcctcaact tgacgagtaa gtcagaaaat caaggtctgc ttgatcctta
     5641 tgtgattatg aagaaaaaga aagactcgga aagtttagca attgatattc tgactttttt
     5701 aacaggaatt tcaagtcgag acggggagaa gtttcctgtg ttacgtaaag ccattcgaac
     5761 ggtgactcaa agtgatcaac gggggttatt acaagttatt aacgaattgc gaaaagacgg
     5821 gtcaccaatc gcggaaaata tcgccgatca tatcgagtcc tttaccgatt atgattttgc
     5881 tcatttgctt ttctcagacg gctcgattac ccaatcgatt agtttagata aacagctaaa
     5941 tatcattcaa gtggcggatt tggttttacc ggatgcagaa acgacttttg aagaatatac
     6001 caccatggaa ttgcttagtg tttcgatgct aatcgtcatt tccacttttg ccttggactt
     6061 tatccatagt aaccgagaaa tcttcaaaat tgtcgatttg gatgaggctt ggagttttct
     6121 tcaagtggct caaggaaaaa cgttatcgaa taagcttgtt cgtgctggtc gggccatgaa
     6181 tgctggggtc tatttcgtca ctcaaaatag cgacgattta ttagatgaac gtttaaaaaa
     6241 taatatcggg ttgaagtttg cttttcgcag taccgatatt catgaaatca agaaaacctt
     6301 ggaattcttt ggtttggatc aggaggatca aagcaatcaa aaacgcctgc gagatttgga
     6361 aaacg
//
LOCUS       DAFLVO010000113         6319 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.115, whole genome shotgun sequence.
ACCESSION   DAFLVO010000113 DAFLVO010000000
VERSION     DAFLVO010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6319
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.115"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(99..1229)
                     /locus_tag="L1U99_002676"
     CDS             complement(99..1229)
                     /locus_tag="L1U99_002676"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HBN1213186.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="L1U99_002677"
     CDS             complement(1878..3080)
                     /locus_tag="L1U99_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1213187.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="L1U99_002678"
     CDS             complement(3140..3343)
                     /locus_tag="L1U99_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HBN1213188.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="L1U99_002679"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="L1U99_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4880..5692
                     /locus_tag="L1U99_002680"
     CDS             4880..5692
                     /locus_tag="L1U99_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1213189.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
BASE COUNT         1877 a         1299 c          996 g         2147 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaat
//
LOCUS       DAFLVO010000114         6173 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.116, whole genome shotgun sequence.
ACCESSION   DAFLVO010000114 DAFLVO010000000
VERSION     DAFLVO010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.116"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            725..811
                     /locus_tag="L1U99_002681"
     CDS             725..811
                     /locus_tag="L1U99_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBN1213190.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="L1U99_002682"
     CDS             complement(932..1621)
                     /locus_tag="L1U99_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213191.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="L1U99_002683"
     CDS             complement(1628..1906)
                     /locus_tag="L1U99_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213192.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="L1U99_002684"
     CDS             complement(1866..2780)
                     /locus_tag="L1U99_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBN1213193.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="L1U99_002685"
     CDS             complement(2762..3142)
                     /locus_tag="L1U99_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HBN1213194.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="L1U99_002686"
     CDS             complement(3592..3879)
                     /locus_tag="L1U99_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBN1213195.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="L1U99_002687"
     CDS             complement(3899..4123)
                     /locus_tag="L1U99_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HBN1213196.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="L1U99_002688"
     CDS             complement(4578..4748)
                     /locus_tag="L1U99_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213197.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="L1U99_002689"
     CDS             complement(4763..5296)
                     /locus_tag="L1U99_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBN1213198.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..6159)
                     /locus_tag="L1U99_002690"
     CDS             complement(5317..6159)
                     /locus_tag="L1U99_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBN1213199.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DAFLVO010000115         6029 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.117, whole genome shotgun sequence.
ACCESSION   DAFLVO010000115 DAFLVO010000000
VERSION     DAFLVO010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6029
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.117"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(68..370)
                     /locus_tag="L1U99_002691"
     CDS             complement(68..370)
                     /locus_tag="L1U99_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213200.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(590..956)
                     /gene="ssrA"
                     /locus_tag="L1U99_002692"
     tmRNA           complement(590..956)
                     /gene="ssrA"
                     /locus_tag="L1U99_002692"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1127..1900)
                     /locus_tag="L1U99_002693"
     CDS             complement(1127..1900)
                     /locus_tag="L1U99_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1213201.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2044..2394
                     /locus_tag="L1U99_002694"
     CDS             2044..2394
                     /locus_tag="L1U99_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBN1213202.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2375..3091
                     /locus_tag="L1U99_002695"
     CDS             2375..3091
                     /locus_tag="L1U99_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1213203.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3091..4539
                     /locus_tag="L1U99_002696"
     CDS             3091..4539
                     /locus_tag="L1U99_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1213204.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4610..5119)
                     /locus_tag="L1U99_002697"
     CDS             complement(4610..5119)
                     /locus_tag="L1U99_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213205.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5109..5834)
                     /locus_tag="L1U99_002698"
     CDS             complement(5109..5834)
                     /locus_tag="L1U99_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213206.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         2052 a         1050 c         1170 g         1757 t
ORIGIN      
        1 aaaaatatcc cttttataag tatggtgata aaatccgttc cgggctacct tttttaggta
       61 gcctacttta atctttatac ctttctggat caacgaaagt atacttcaaa tagtcataac
      121 gccgatgatc gctccgtgcg tctggcacat cagtcacgat atcaaacaaa aaatacacat
      181 ctttcttcat tctggttttt gttgccggaa ttttaaagta gttcttatta gagtaataga
      241 gattgattaa taagctatct tcgattgcta aaaagaaaac ttctgaatcc cacaccttat
      301 aaaaatcttt gacaaatcta ttcgaaggat caaatttaaa ccataattgt gtttttcctt
      361 ccatcaacat aatgttcacc tcaaaaagag tatacgaact aatgttcttt ttgtaaagta
      421 ggaatatcat tgataatatg gatggaacat atatattaaa aagtgttctt tttgaatgct
      481 attttgaatg ccattttcat tcatttaacg aaaatctgcg aaaataaaaa atgctcaaac
      541 ccttataaaa taaggattta agcatctagc gaaatctgct gaaatctcac aatggagacg
      601 gcgggagtcg aacccgcgtc caaacacatc gccacttaaa aatctacgtt catagtcaac
      661 tcatttaagg attcacttta cagcttgccg agtgacaggc attctgtatc gctagtctga
      721 tgttctcttt ttcaacttac agacggaaag ttgaaacgta tcccactaaa gttaggaccc
      781 ttactcgagc acatgggcga tgccgagagg atctacgcta actgttttta ggcagctaaa
      841 gcgtaagagt tgttttcgtt tttagcagtt atatttaact gtaacgtttt tacgtagacg
      901 taacctacga aacgcaattc aagctcgact gtgcctgtcg aatccgtaac gtccccgtta
      961 gctaacaagg gttacgtgta tttttcatac aaaattagta tagcatatat tgggataaat
     1021 tcaataaaaa agcgaatcat atcccattat ttatataata actgcccctt tcttaagaaa
     1081 aaataagcga ttttcttaag aaaagaggta gcttcaaaaa aagatcttaa atcagatcaa
     1141 aatacttcaa tgcgtggaca attccgcctt ctgtattttt ctttgtgata aaggtagaaa
     1201 gttcttttaa tccgtcatag gcgttgccca tagcgatttt gttgtcgcaa gcttccaaca
     1261 aggcaaaatc attcggacca tcgccaaatc caaaagtagg aactttttcc agctgaagtt
     1321 ctttttgcag acgtttgaca cctgcccctt ttgagattcc tttcttcact gtatcgatcg
     1381 agtaaggacc attccgataa aaagttagct caggaaaatg ttcgtgatag tattcgtcac
     1441 ctgattgaga taagatcagc aacatattta ctgtgttttc tttaaagcct aaaggatcaa
     1501 tttccggaac atctgaatga atgaagtcgt aagcattgat cattgtttgg ctatgaccgg
     1561 tacaccagat tttctgatcg ttatagtaag aaagttcatg accgttcaac tgtacatgat
     1621 catacatttt ttgacattct tctgaagaaa atgtttgaga atagatttct tcgccgtcta
     1681 ctcgaatgaa agaaccattc atggtgaccg cagaagtaat gcccgcatct tccatgatag
     1741 agtggatttc tgcttctgta cgtcctgtag cgatgacggg gagaacattg ttttctttta
     1801 atgcgttcat agcttttgcc acttcgggtg tgatttttga tttcgcatct agtaatgttc
     1861 catcaagatc aaagaaagtg attgcacgat aatttgacac aaataaaact ccttttttat
     1921 tggaataagt ttatcttaac aaagaatgaa caaaagacaa acctttcgtg aagaattcct
     1981 gaacatattg gttcagtcaa caatttagag tatactataa gaagagaatt taggagggaa
     2041 agaatgattt ttttcagtat tggtatctta ttcttaataa ttggcagtct ttttcggatt
     2101 ctgccctcaa aaggaaatct gcctttttat gggtatcatt cgcctcttgc cgcaaaaaca
     2161 gacgctcatt ggcggctggc tcaaaagaca agcggaaact ggttttttct tatgggctta
     2221 ctgatggcat tgatcggcta ttatttaaag acatctgggc atacgaatta ttttctgatt
     2281 gaaatgcttc tgctagtatt tccaattatg cctattttta ttatgacaga aaagaaatta
     2341 cagaaatatg acctggaaac tggagggaac gataatgaat attttaatga ttgaagataa
     2401 tcaatctgtt tctgaaatga tgcagatgtt tttcttaaat gaaggttggg aagcaacttt
     2461 caagtatgat ggaaaagaag ggctcgatgc ctttttagaa aacccacaac attgggatat
     2521 gattacacta gacctgaatt tgcccacact ggacggtatg ctagtaggaa gagagatccg
     2581 caaagtttca agtactgtgc cgattatcat gctgacagct agagattctg aaagcgatca
     2641 ggtgatcggc ttagagatgg gggcagatga ttatgtcaca aaacctttca gtcctctgac
     2701 gcttattgct cgaatgaaag ctttgcatcg ccgtagtgag ttggcagaag caagagaaga
     2761 agcagtagtt tcagatgatc attttgatat cgagactagt catttcaaga tgaatacgaa
     2821 aacacgagaa gcgtatctgg acaaccggcc aattgaagga ctgacgccta aagagttcga
     2881 tctattgttt actttagcaa aaaaaccacg tcaagtattc tctcgggagc agttgcttga
     2941 attagtctgg gattatcagt actttggtga tgaacggaca gtggacgccc atatcaagaa
     3001 attacgacaa aaaatcgaaa aggtcggacc acaagtcatc caaactgttt ggggagtcgg
     3061 ctacaaattc gatgattctg gtgttgccta atgcgttatt tgtatcagca actcttagct
     3121 ttctgcggaa tggtcgcgtt gatcttattg atcgttggag tttcttttac acaactgaca
     3181 aaacaaacga ttgaagaaaa caattaccag caactgtttg gatatgctga atcagttgaa
     3241 aagacaacgc aaacctatgc cgatacgctc ccgcagttta gtcaagatca ggcgtttcaa
     3301 aatgcattgc tgctgacaga gcaagtactg acagaacaaa atgtgaactt tatatttatc
     3361 gataaaaacg aacgtgtcat ttatccgact aatacagctt tactgaattt taccttaaca
     3421 gctgatcaat ggaaaaatct gaggaatgga cgtcaagaaa aattcacatc gaataaaaat
     3481 attttaggac aagcacaggc gacctcttac gcacttgtgc catttaattt gaatcatgaa
     3541 ttctatggag cacttgtagt tagtcaacct gcgcgaaata tcgataacag cgttcgtcca
     3601 attacactga acctgttcaa aggatttatt ttttccagta tcgttgcagt tattgccagc
     3661 tatgcttttg cagcattcca agttaagcgt atcaatcggt taaggaatgc gacgaaagaa
     3721 gtgacgaatg gtaattttga tgtacagctc cccgtacatg acaaagatga atttgatgag
     3781 ttagcagatg atttcaataa aatgacgaat tcattgaaag aatctcaagc agaaattgaa
     3841 gaacaagaaa atcgtcgaag acaatttatg gcagatgctt ctcacgagat gagaacacct
     3901 cttacgacaa tcaacggact tctggaaggg ttagaataca atgcaatccc tgaaaatcag
     3961 cgagaaaacg cgattaaatt gatgaaaaat gaaacagagc gtctgatccg tttggtgaat
     4021 gaaaacttgg attatgaaaa aatccgtacg aatcaaatca gtatggtcat taaaaaattc
     4081 aatggaacag aaacattgaa aaatattgtt gcacagttag aagctaaagc agaagcagca
     4141 ggagatacat tgacattgaa agccgttgat gatattgatg tttacgctga ttatgaccga
     4201 tttgtccaaa tcatggtcaa tattattcaa aacgcgatac agtttactga aaacggccaa
     4261 atcacgatta ctttagaaaa aggctatctt gaaacgatca tcacgattga agatacggga
     4321 attggaatgt ctgaacaaca aatgaaaagt atctgggatc gttattataa agtagatcct
     4381 tcaagaaaaa atacaaaata tggtgaatca ggattaggtt taccaatcgt gcagcaactt
     4441 gtacgcttgc ataaaggaaa attagaagta gaaagcgaac taggaaaagg aacaaaattc
     4501 gctgttcgtt tgcctgacgt agaaatcaaa aaagagtaaa aaacaagcgg tataaaagat
     4561 catgaatcga tcttctatac cgcttgtttt ttactataaa atgattgatt tagcccgcgg
     4621 gctctaaacg atcaatataa ggactttgag caatagtagc atcatgagta aagagtaaga
     4681 taccttgatt ttcttcatga gctaaataag aaagcaagtg gagtagctct tggatctcca
     4741 atacactaag ttcatcaaat gtatcttcaa taacaatatt gtttcgcttg gaaagcaagg
     4801 catgaagtaa ttgcagcttt actttttcaa aagacgtcaa ctcagctgcc gcacaattaa
     4861 gcaaggaagg agagatatca agtttttctt gataggccaa acgatcttgt ttgatttctt
     4921 tttccggtac atccaacagg acatggtctt taagattcag ataaggaaac atcggccaat
     4981 ttttttggat gatcgcaaaa ttatccagtt ttgcaacaag aacctctttt ttcaagtgct
     5041 ccaatatttt atgctgtttt tcgagaggac acaaaataac ggtcaagtgt tcagcatgaa
     5101 tcaaatattc aggtttcatt acgtccaggc ctcctacttt gcaaatgatg gataaaaaaa
     5161 gtgaaaggga atagactaag aatgagacag catccactga gcccaataag agtttgggca
     5221 aatcccttaa gtatatctgt gaaaaaaaga tcattttgga aatcgatggt aaaaaaagtc
     5281 tgttgatcca tcggaattgt aagtccgctt accgaagtca agatatcacg gatatctggc
     5341 agttcagtag tctttaagac aagaaaattg atcctttgaa gaagcgcttc ataaactgac
     5401 tggaagctta cgatccacaa taaaaccaag atacaacaaa gaaagagagg aaagaacagc
     5461 tgccagaaaa taaaaaggaa taatttggtt ttagaaagac cagtcaggtg ccaattgatc
     5521 aattcctgct tgttttgcct gactgaatag taaaagaaaa agataaaaag gaaggcaaat
     5581 agaaaaaata aactgaatat gccttttata taaaatcggc tagctaattc taaagccgga
     5641 agaagctctg tagatgcaga agcgccaata aatgaaagcc gatcttggac ttgattggct
     5701 aaagccgatt gcaaatggta aagagtcagg catgctatca ataaaaaagc agaaaagctt
     5761 gaaaataaac aatagagtat tgtctgcttt ttgtaataaa ttaatcgagc agtagcatag
     5821 cggattattt tcatactttt cacctctata aaaagtatag aaaatgaata tgaataaagt
     5881 atgaaattcc tttagtgaaa tcacgaatta aaaccagaaa atattttgta aaaagcaaga
     5941 ggttgtgaag aagctgccct attctattac cgtagatgca agcttttgaa cactgtttat
     6001 tcgaaaagag gagcagcgac aataatttt
//
LOCUS       DAFLVO010000116         5977 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.118, whole genome shotgun sequence.
ACCESSION   DAFLVO010000116 DAFLVO010000000
VERSION     DAFLVO010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5977
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.118"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..453)
                     /locus_tag="L1U99_002699"
     CDS             complement(<1..453)
                     /locus_tag="L1U99_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1213207.1"
                     /translation="MKYKEMFVPSLIQLAVEVKNKEEAFLIAAQQLEKMGYVNENYLN
                     GLIAREREFPTGLITKYLNIALPHSECEYVEKPFVFVMQLKNPIYFYQMGDNQEMTVE
                     NLFFLGIKEPKEQVGLLQAFMNLFMDETFVENYKKQETPQNIYELITNY"
     gene            677..1468
                     /locus_tag="L1U99_002700"
     CDS             677..1468
                     /locus_tag="L1U99_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBN1213208.1"
                     /translation="MLKKERQEQIITLLEKDFYLTNSEIANKLGVSEMTIRRDVTELA
                     KKNKVKKLYGGVERKEPYNRELSTQEKIDTNVAEKKYIGQVMNSMIPDNSTIYVGAGT
                     TILYALPFIQKKNLFVITNSLIAFNYLKNHTSYRILLTGGEFSPITEEFIGEVAERSF
                     ESLNVDISFAATNGIFDNNVTTAQFIEGNIQNAALNAAKIKCIVADYSKLNKSDVYTF
                     RKLTDFDYLITDNHLSEQDFNHYSKYLTILKEPKNDTDNHDEPIH"
     gene            1434..2387
                     /locus_tag="L1U99_002701"
     CDS             1434..2387
                     /locus_tag="L1U99_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HBN1213209.1"
                     /translation="MILTITMNPSIDSIYFTKHFELGTMTRFDSPVRYVGGKGINCGR
                     ASALLGSSVILTGFLGGYFGSMIQDMLKNENLFDLHFLPIAEESRGAVTIMHDDETQT
                     ELVEAGPEIADTTIKKLMNDIKLISKNNYLSVITINGSVNNPDPFLYAKLLQYIKEQI
                     DPSTYILMDISGQHLREVLASKYKPMFIKPNIHEFSDIIHQKITQKSDIKHHLKTNPL
                     FKDIDVIMISCGSYGAVVKVKEEFWNVEIPKIPIINTTGSGDATVGGFAHSLEQNYPL
                     KECVRYAMACGMSNAQQSEVGKVIPADVKNLAKSIKITEMK"
     gene            complement(2785..3759)
                     /locus_tag="L1U99_002702"
     CDS             complement(2785..3759)
                     /locus_tag="L1U99_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1213210.1"
                     /translation="MNKELNITQEWDKVFPKSNQVNHRKVSFPNRFGITLVADLYEPK
                     EVSEKKLPAIAVSGPFGAVKEQSSGLYAQTMAERGFLTIAFDPSFTGESGGVPRYVAS
                     PDINTEDFQAAVDFLSVQKNVNPERIGIIGICGWGGMALNAAAIDTRVKATVVSTMYD
                     MTRVTANGYFDVMDENARYEMREELNAQRIIDFKQGDYARAGGVVDPLPEDAPQFVKD
                     YHAYYKTDRGYHVRSLNSNDGWNRTSGLSLMNAKLLHYIPEIRHAVLVIHGEKAHSRY
                     FGEDAFKELKGDNKELMIIPGASHTDLYDQTDIIPFEKMATFFEENLV"
     gene            3874..4308
                     /locus_tag="L1U99_002703"
     CDS             3874..4308
                     /locus_tag="L1U99_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBN1213211.1"
                     /translation="MYSIGQVSEMFGLPVSTLRYYDKEGLFPDIQRVSGIRKFSENEL
                     EALRVIDCLKKSGLEIKDIKQFMEWSKEGSKTFEVRKELFEKQKEVVEKEIAKLERVL
                     AMLNYKSWYYEEAIKAGNEEAVLTMIPDDLPQHVKEAYVHSH"
     gene            complement(4433..5455)
                     /locus_tag="L1U99_002704"
     CDS             complement(4433..5455)
                     /locus_tag="L1U99_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HBN1213212.1"
                     /translation="MKKIGFLSFGHWMEQGSLVKSAQDAYLQSIDLAVEAEKIGVDGA
                     FFRVHHFAPQIGSPFPLLAAIGAKTSKIEIGTGLIDMRYENPYYMAENAGLTDIITQG
                     RVQLGVGRGSPEQVLDGWKYFGYDYSEEEIKEVTRERTLEFLELLEGKPFEEPNPQPM
                     FPQGSGKLRIEPYSEGLRQRIWWGAGSQQTAIWAAQHGMNLQSSTLVNYESHEPFHIQ
                     QANQLRAYKEAWKQAGHDFEPRTLVTRSIQPITTDLDRRLFGQDGSPQQDAVGYLAYH
                     RNPTIFGKTFAGEPDQLIKELAEDEAIKEADTVLVTIPNTLGVEYNMHLLETIVKDIA
                     PELGWR"
     gene            5847..>5977
                     /locus_tag="L1U99_002705"
     CDS             5847..>5977
                     /locus_tag="L1U99_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (thioredoxin)"
                     /protein_id="HBN1213213.1"
                     /translation="MKKIYFLCTGNSCRSQIAEGYARKYLSPSMFEIRSAGIETHGL"
BASE COUNT         1880 a         1126 c         1029 g         1942 t
ORIGIN      
        1 ataatttgta ataagttcgt atatgttttg cggtgtttct tgtttcttgt aattttccac
       61 gaatgtttca tccatgaata aattcataaa cgcttgaagt aatcctactt gttcttttgg
      121 ttctttgatt cctaaaaaaa atagattttc tacagtcatt tcctgattat cccccatttg
      181 ataaaaataa attgggttct tcagctgcat aacaaaaaca aatggctttt cgacatattc
      241 acattccgaa tgtggcagcg cgatatttaa atacttagta atcaatccag taggaaattc
      301 tctttctctt gcaatcagtc cattcaaata attctcattg acgtacccca ttttttctaa
      361 ttgttgtgca gcgattaaaa aagcttcttc tttatttttt acttctaccg ctaattgaat
      421 caaactagga acgaacatct ctttatattt cattccaacc tcctcctttt tgattaagtt
      481 tgttaattta ttgttctact aaattcatct ttgttttaca agaacattat atttctgtta
      541 gtttgttttg tcaacgcttt caaaagaaat ttattttgtt aaatttgatc tacttgaaaa
      601 taaaatcgtt tatctatata attaagaaga acaaagtcga acaaaaattg acttttatgt
      661 taaaggagta attcatatgc tgaaaaaaga aagacaagaa caaatcatta cattattaga
      721 gaaagatttt tatttaacta attcagaaat cgctaacaaa ttaggcgtat cagaaatgac
      781 catacgccga gatgtcactg aattagcaaa aaaaaataaa gtaaaaaagc tatatggtgg
      841 cgttgaacga aaggaacctt ataatcgaga actatcgact caagaaaaga ttgatacgaa
      901 tgtagccgaa aaaaaatata ttggtcaagt catgaacagt atgattcccg ataattctac
      961 tatttatgtc ggtgctggaa caacgatcct atatgcactt cctttcattc aaaagaaaaa
     1021 tctatttgta attacaaaca gtttgattgc tttcaactat ttaaagaatc atacaagtta
     1081 tcggatttta cttactggtg gcgaattttc tcctattaca gaagagttca ttggggaagt
     1141 tgcagaaaga tcttttgaaa gtttgaatgt cgatatctct ttcgctgcaa caaacggcat
     1201 atttgataac aatgtgacaa ccgctcaatt tattgaggga aatattcaga acgcagcgct
     1261 caatgcagca aaaatcaaat gcattgttgc agattattca aaattaaata aatcagacgt
     1321 ctatactttt agaaaattaa ccgattttga ttatctaata accgataatc atttatcaga
     1381 acaggatttc aatcattatt caaaatactt aacaatatta aaggagccca aaaatgatac
     1441 tgacaatcac gatgaaccca tccattgatt ccatttattt tacaaaacac tttgaattag
     1501 gtacgatgac acgctttgat tctccggtac gctatgtagg cggcaaggga atcaattgcg
     1561 gacgagcttc tgctctacta ggttcatcag ttattttaac agggtttttg ggcggttatt
     1621 ttggcagtat gattcaagat atgctgaaaa atgaaaattt gtttgatttg cattttttac
     1681 ctattgcaga agaatcaaga ggtgccgtca cgatcatgca tgatgatgaa acgcagacag
     1741 agctagtgga agctggtcct gaaatagcag atactactat caaaaaatta atgaatgata
     1801 tcaaactaat cagtaaaaat aattaccttt cagtcattac aataaatggt tctgttaaca
     1861 atccagatcc ctttttgtat gctaaattat tacaatatat caaagaacaa atagatcctt
     1921 ccacctatat attaatggat atatctggac aacatctccg tgaagtctta gcaagtaagt
     1981 ataaaccgat gttcatcaaa cctaatatcc atgagttttc agatatcatc catcaaaaaa
     2041 ttactcaaaa aagcgacata aaacaccatc taaaaacaaa tccactattt aaagatatcg
     2101 atgttatcat gatttcttgc ggctcgtatg gtgcagtagt caaagtaaaa gaagaatttt
     2161 ggaatgttga gatccctaag attcctatca ttaatacaac aggctctggg gatgccactg
     2221 ttggaggttt tgctcattca ttagaacaga attatccttt aaaagaatgt gtaaggtacg
     2281 caatggcttg cggcatgtcg aatgcacagc aatcagaagt cgggaaagtt attccagctg
     2341 atgtaaaaaa tttagcaaaa agcattaaaa tcacagaaat gaaataaata gtacaaagta
     2401 aataattgtt tatatgaaat gagacacaaa gagactgtga caaaaaacgt gtgtaccgac
     2461 ccccaaaagt tagatttttt ggtctaactt ttgggagtcg atacattgtc acagtccttt
     2521 tttcgaataa acggtgttct cctgccaact cctcggtcac aagtcacaat attcaacaaa
     2581 catgagaagc tattttttga aattgctcct tgtgactcag agttaaacgg caggctcacg
     2641 acctcttggt ataaacggtg ttcaaaagct tgcatctacg ctaatgagtc caaccaagtc
     2701 aaaaatgagg agcttttttg gctgtcctta ttacttgatg cagggcagtt ttttcataat
     2761 ctcttttaga ttaaatcctt ttggttacac aaggttctct tcaaagaatg ttgccatttt
     2821 ttcaaatgga atgatgtctg tctggtcgta tagatctgta tgggatgctc ctggaatgat
     2881 catgagttcc ttgttgtcac cttttagttc tttgaaagcg tcctccccaa agtaacgtga
     2941 atgagctttt tccccgtgaa tgactaagac tgcatgacgg atttctggaa tataatgcaa
     3001 tagttttgca ttcataagtg acaaccctga tgtcctattc caaccatcat tggagtttaa
     3061 agaacggaca tgatatccgc ggtctgtttt ataatacgca tgatagtctt tgacaaattg
     3121 aggagcatct tcaggcaacg gatcaaccac acctccagca cgtgcgtagt ccccttgttt
     3181 gaaatcaatg atgcgttgtg catttaattc ttcacgcatt tcatatcggg cattttcatc
     3241 cataacatcg aagtagccat ttgctgttac tcgagtcatg tcatacattg tggaaacaac
     3301 tgttgctttg acccgcgtat cgatagctgc tgcattcaat gccatacctc cccatccaca
     3361 aataccaatg attccgattc tctcagggtt tacatttttt tgtacagata aaaagtctac
     3421 tgccgcttgg aaatcttccg tattgatatc aggcgaagca acatatcgag gtactcctcc
     3481 gctttctcct gtaaacgatg gatcaaacgc aatcgttaaa aagcctcttt cagccatcgt
     3541 ctgcgcatat agaccagacg attgttcctt cactgcacca aatggcccgc tcacagcgat
     3601 tgccggcaat ttcttttcac ttacttcttt tggttcatat aaatcagcga ctaatgtgat
     3661 accaaaacga ttcgggaagc tcacctttcg atgattgact tgattgcttt ttggaaatac
     3721 tttgtcccat tcttgtgtga tgtttaattc tttattcata ttctagactc tcctttgatc
     3781 aaaattgaca tttgtttttg aatgtattat tatgataaaa cttaaacttg actttaggtc
     3841 aaggtaaaaa ttttatttta ggaggatttt tttatgtatt ccattggaca agtgtctgaa
     3901 atgtttggat tgcctgtttc tactttacgt tattacgaca aagagggatt atttcctgat
     3961 atccagcgtg tttctggtat tagaaaattt tcagagaatg agttagaggc tttaagagtc
     4021 attgactgtt tgaaaaaatc tggtttagaa ataaaagaca ttaagcaatt catggaatgg
     4081 agcaaagaag gcagtaagac atttgaggtt cgtaaagaac tatttgaaaa acaaaaagaa
     4141 gtagtagaaa aagaaatagc aaaattagaa agagtactcg ctatgctaaa ctacaaaagc
     4201 tggtactatg aagaagcaat aaaagccggc aatgaagaag ccgtattgac aatgattcct
     4261 gatgatttac cccaacatgt aaaagaagct tatgtacatt ctcattgaac aaacggataa
     4321 ctcactctcc ttctctatga acttcatgaa aacatgaata aacacctcta actgattgtt
     4381 agaagtgttt attttttcac tcaagtatcc tgcacttaca aaaatatcct ttttaccgcc
     4441 atcctaattc tggagcgata tcttttacga ttgtttcaag caagtgcatg ttatattcta
     4501 cccccaaagt attaggaatc gtgacaagta ctgtgtctgc ttctttgatt gcttcatctt
     4561 cagctagctc cttgattaat tgatcaggtt caccagcaaa agtttttcca aaaatcgttg
     4621 ggtttcggtg ataagcaaga tagccgacag catcttgttg cggactaccg tcttgtccaa
     4681 ataagcgtcg atccaaatca gtggtgattg gctgaatcga gcgagtaact aatgttcttg
     4741 gttcaaaatc atgacctgct tgcttccacg cttctttata cgcacgtaat tggtttgctt
     4801 gttggatatg gaatggctcg tgggattcgt aattgactaa tgtagatgat tgcagattca
     4861 ttccatgttg tgctgcccag attgccgttt gctgcgaacc agctccccac cagattcttt
     4921 gtcgtaatcc ttctgaataa ggttctatcc gtaattttcc tgatccttgt gggaacattg
     4981 gttgaggatt tggttcttca aatggttttc cttcaagtaa ttccaagaat tcaagggtgc
     5041 gttcccgtgt tacctctttg atttcttctt cactgtaatc ataaccaaag tatttccagc
     5101 catctagaac ttgttcaggt gaaccacgcc ccactcctag ttgcactctt ccttgcgtga
     5161 tgatatctgt caatccggca ttttctgcca tataataagg gttttcatat cgcatatcaa
     5221 taagtcctgt accgatttca atcttacttg tctttgcgcc gattgccgct agcaaaggaa
     5281 acggcgaccc aatctgaggg gcaaaatgat gtacgcggaa aaacgctccg tccactccga
     5341 ttttttctgc ttccaccgct aaatcaatcg attgcaaata agcatcttga gctgatttca
     5401 caagcgatcc ttgctccatc caatgtccaa agcttaaaaa gccgattttt ttcaaggtaa
     5461 tgacctcctt taaacctaca aaaatggaag gttttttatt tttaatatga actgattcta
     5521 ctactttttt tcttaaaaga cgaataattg ttctcgcctc acaatcaaga aatgtatcgg
     5581 cttactacac ccctactttc ttcatcatct gccgtgtctt aatctctttt aacagtctgt
     5641 tacatcgttg atttttgact caaaatgatt gtttctaaca tgtatttatg gtaaaaaaga
     5701 caagattagt tctttgtaca catcgattta tacgctgaac aaaaagaaat atataaacta
     5761 agaaacccat tgttttttcg ctccatcaca tagagtttac tttagataaa cagtgacatt
     5821 tactaatcca taacggagga aatcaaatga aaaaaatcta tttcttatgt acgggcaatt
     5881 catgccgcag tcaaatagca gaaggctacg cgcgtaaata cttgtctcct tcaatgtttg
     5941 agataagaag tgcggggatc gagacacatg gcttgaa
//
LOCUS       DAFLVO010000117         5803 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.120, whole genome shotgun sequence.
ACCESSION   DAFLVO010000117 DAFLVO010000000
VERSION     DAFLVO010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5803
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.120"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..747)
                     /locus_tag="L1U99_002706"
     CDS             complement(<1..747)
                     /locus_tag="L1U99_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1213214.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSDTFSLDKDYELLNPIIKNIFTKYYSKDFEIYLNEILANNINPLIEEYANQRH
                     SISKELFFKRANSKLQDKIRNGDFKYGEKERMIDSLKQLLDEMDLAYKDISKYSSVED
                     FFYKITKNQFETEKFISDLSKKYNFPYEKNS"
     gene            949..1248
                     /locus_tag="L1U99_002707"
     CDS             949..1248
                     /locus_tag="L1U99_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1213215.1"
                     /translation="MEAIKLMISEEQEEMFLKQFYQIATKAIEKAQENAGMTREYLNQ
                     KEMAEYLNVSENFLKNAVRNEGLPVVELGARKFYSKKAVNEFMFARMKRGENIGR"
     gene            1513..2388
                     /locus_tag="L1U99_002708"
     CDS             1513..2388
                     /locus_tag="L1U99_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213216.1"
                     /translation="MNAIVILAEITYWYRPKKIFNDDGQLLGYQKKFLEDILQKSYKQ
                     LSKKTGLSERAIKDAIVYLEKKGIIKRVFRNIYYEKRAVTLSNVMYIVLNVHKLIEIT
                     FPTLDCEKKEYMPKIRQRGIEKKRYVSLKKGRGMYKFVYTYTKTTSQNISKTTLVMEE
                     EDINIKRIYSKISVLYDANNEDGRKLFQVYHYLRNANVDTEDIRKIIEYLSENTQYLI
                     AECIIKQHEACFFQRKTEEGLYDYVTYFLNGLQKRYKSQFLENVEPIDQFKKAFEIKE
                     LPEITMHNWLKGEES"
     gene            2385..2603
                     /locus_tag="L1U99_002709"
     CDS             2385..2603
                     /locus_tag="L1U99_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213217.1"
                     /translation="MIKNRLIDQMWCLDQNTDTLELIESICFNTVVLDLRAENDNCVT
                     HIIINQKMAQQLSESLRKWAEGENYESN"
     gene            2590..5217
                     /locus_tag="L1U99_002710"
     CDS             2590..5217
                     /locus_tag="L1U99_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213218.1"
                     /translation="MKAIKEKIVSRKINWLALSVLVLMISVVFTSNIVEASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSVINTIVVGLMILSLMFVGYKMITGKGTIDLRSVGMNIVMSVALI
                     LLMPTMISSGIQFAKIFYNDATTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNKLTRKNFQQTDLTQVLTDKVIDKLEKENPAADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNAGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSTGFNRAKGSGN
                     GNGSDSGEGEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERAIK
                     PFKSMRDMANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPTRLSDR
                     KDGAKVENADRIMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMHGQAKS
                     AEELINQKRQEAKYTPEAMNREEMLRKRVEGRTGANTDEKEALTKERIQEAKNSNTGL
                     EKLVKENLQNSTSSQGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNGQGTKTIDV
                     RENVQNSTSSQGFKSMDVRENVQNSTSSQGFKSMDVRENVQSSTSSQGFKTVDVRENV
                     QKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKPRRRFTYEDNE
                     LFRDTLNDPNPLFDNLLKK"
     gene            5232..5450
                     /locus_tag="L1U99_002711"
     CDS             5232..5450
                     /locus_tag="L1U99_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213219.1"
                     /translation="MKLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKHEIKNNLKYCYLEKSEEIIHELNGF"
BASE COUNT         2185 a          732 c         1112 g         1774 t
ORIGIN      
        1 actatttttc tcatatggga aattgtattt tttactaaga tctgaaataa atttttctgt
       61 ttcaaattgg tttttagtaa ttttataaaa gaaatcctcg acagatgaat actttgaaat
      121 atctttatag gctaagtcca tttcgtctaa tagctgtttt aaagaatcaa tcattctttc
      181 tttttcaccg tatttgaaat caccatttct tatcttgtct tgaagtttac tgttggctct
      241 tttgaaaaat agctctttag agatagagtg tctttggtta gcgtactctt caatcagagg
      301 attgatatta ttagcaagta tctcatttag ataaatttca aaatcttttg agtaatattt
      361 tgtaaatata ttttttatta taggattcaa taactcatag tctttatcta gcgaaaacgt
      421 atcactatat ctttcttgaa tgtctttaaa gactttgtga ggtatttctg ggaagtcctt
      481 aatatatagc tcatacccta tatcgataag gtatgaagtt atatattctt ctaaagttcc
      541 ccatttaatc cagtcaattg ttgaattagt gatagttgat aataatttca gcttttgtgg
      601 atttggtaaa ttggtcccac gttcccagtt ggatatggtc gcacgtggtg aattatctat
      661 tttccttcca agttcttcca tagtaaaacc acatgaaagg cgtaattgtt tgattcgttt
      721 tcctgcttct gaaggatttg gcttcatctt ttttctcctt tttattttta aagatagtat
      781 atcatattta taaaataaaa gtatttaaaa gtatttactt tttatctgga gtatgatact
      841 ttattcttat aaatacaaat aaatacattt ttttacgcaa tttgtattta tttgtactta
      901 taaaggtaga ggagttatag aataattaat taaaaaggag aggtttttgt ggaagcaata
      961 aaattaatga tttcagaaga acaggaggaa atgtttctaa agcagtttta tcaaattgct
     1021 acaaaagcta ttgaaaaggc tcaagaaaat gcggggatga caagggaata tctcaatcaa
     1081 aaagaaatgg cggaatactt aaatgtgagt gaaaactttt taaaaaatgc tgtgagaaat
     1141 gagggattgc ccgtagttga attaggggca agaaaatttt attcgaaaaa ggcagttaat
     1201 gagtttatgt ttgctcgaat gaaaagaggg gaaaatattg gaagatgatg aagtagaaat
     1261 tataaaaaaa tgctttaaaa aaagaaaaaa agtgttccca aaagtttgca gactggggga
     1321 acactcaata ataaagtgct gagaaaactt tatttatagc tattatatca aaaaagaagg
     1381 tgaaaaggtg ttttcttctg gaaatgttgt agttgacaaa cttagagaaa taaattttga
     1441 cggaaatgta atccacacac atggtacgat caattaagaa aaaaaacgaa aaaaggtgtt
     1501 gagaagccct atttgaatgc aatagttatc ttagcagaaa ttacctattg gtatagacct
     1561 aaaaaaattt ttaacgatga tggtcagcta cttggttatc aaaaaaagtt tcttgaagat
     1621 attttgcaaa aatcatataa gcaattaagc aaaaaaacag gattatcaga acgagctata
     1681 aaagatgcaa ttgtgtactt agagaaaaag gggattatca aaagggtttt tagaaatatt
     1741 tattatgaga aaagagcagt tacattatca aatgttatgt acattgtttt aaatgtacat
     1801 aaattgatag aaattacttt tcctactttg gattgcgaaa aaaaggagta tatgccgaaa
     1861 attcgtcaga ggggtatcga aaaaaagaga tatgtctctt taaaaaaagg tagaggtatg
     1921 tacaaatttg tatatacgta tacaaagact acttcacaga acatatcaaa gactactctc
     1981 gttatggaag aagaggatat taatataaag aggatttaca gtaagattag tgttctttat
     2041 gacgcaaata acgaagatgg tcgaaaatta tttcaagtgt atcactattt gagaaacgct
     2101 aatgtagata cagaagatat cagaaaaatc attgaatatt tatctgaaaa tactcagtat
     2161 cttattgctg agtgtattat aaaacaacat gaagcatgct tttttcaaag aaaaactgaa
     2221 gaagggttat acgattatgt aacatatttt ttgaatggac ttcagaaaag atataaaagt
     2281 caatttttag aaaatgtaga gcctatagat cagttcaaaa aagctttcga aatcaaagag
     2341 ttacctgaaa ttactatgca taattggttg aaaggagaag aatcatgatt aaaaatcgct
     2401 taatagatca aatgtggtgt cttgatcaaa atacagatac tctcgaatta atcgagagta
     2461 tctgcttcaa cacagtagtt ctcgatttaa gagctgaaaa tgacaattgt gtaactcata
     2521 tcataattaa tcaaaaaatg gctcagcagc tctctgagag cctaagaaaa tgggctgaag
     2581 gagaaaacta tgaaagcaat taaagaaaaa atcgttagta gaaaaataaa ctggttagca
     2641 ctcagtgtac ttgttttaat gattagcgtt gtttttacaa gtaatattgt tgaagctagc
     2701 attttcaatt ggtttgatga cacaaaaagt caaacagagt ttttgaataa ttctctttat
     2761 agaccttacc taaaaaaata caatggagat ttccttagtc agttcgggat ttggcttgga
     2821 tgggctgtgg taaaaggcat gtttactgtg actgattcga ttcaaaatat gattccagat
     2881 gtgttggatt tgttcaattt cattgaaagt acagggctaa ataatgttta tcaatcagtc
     2941 ataaatacaa ttgtcgttgg attaatgatc ctttcattga tgtttgttgg ctacaagatg
     3001 attactggaa aaggaacaat agatttaaga tctgttggaa tgaatatagt gatgtctgta
     3061 gcgttaattc ttttaatgcc aacaatgatt tctagcggta ttcaatttgc caaaatattt
     3121 tacaatgatg ctactacgat tacaaattca gatgacggag tcgcttggtc attgataaaa
     3181 caaggagtaa cagatctggc atatattaat aaaacagatc aatactcaag cattgataaa
     3241 acggaggatc gaaataagtt aacacgaaaa aattttcaac agacagattt aacacaagtg
     3301 ttgacggata aagtgattga taaattggaa aaagaaaatc cagctgcgga taatcttcgc
     3361 tatgaattag ttgaaaattc taataatgaa tttgttgcca caaagttttc tgataacttc
     3421 ttatcaacat tttctgatag cttgaaatca ggttattatc gatatcaagc aaatctttgg
     3481 gggatttcga ttgggttgac agcgttggca atcgcctatg tgttcagcgc gtttgtgatc
     3541 attacagcaa tattagaact tgcatttaaa cgtgtgttag gtgttcttgt ttttgcgaca
     3601 gatattgaaa caggacaacg ttcaaaagtt gttttatccg atattttaca atgttactta
     3661 acagttggat ttcaagggtt tggactatct atgtttgcta tgtttatcaa ttttttaaat
     3721 gctggacaag gtatctccac aaatattttt ataaaaacaa ttgcttatat ctgtgctgtg
     3781 tttgtgctga taaaaggcag tggaacagtc atgagatact ttggtgttga tattggactc
     3841 aaagaaggct atgggcaact tgcttctgct tttggtatgg gcgcaatgct gtttagaaaa
     3901 ggatcaactg gatttaatcg tgctaaagga agcggaaatg gaaatggatc agacagtgga
     3961 gaaggagaag atcgaaaacc agaaaagaat ttcggcgaaa ctctatcaaa aaaagctggc
     4021 aaaactggaa gagctttggg atatgcccat gaacgtggat tatcaggttt agcttcagat
     4081 ggagctacaa tggctagtga aagagcaata aaaccattta agagtatgcg tgatatggct
     4141 aatgatacca agaataagtt caaagaaggt ttagatgatg gtacagtgtc cgctattaat
     4201 aaaaatagca aacctatgtt agctaaaaat aaagaagatg aaactggaaa atatgctgat
     4261 tccatgccaa cacgtctttc ggatagaaaa gatggtgcta aggttgaaaa tgccgataga
     4321 attatgtcta gttctgaacg tatgcgtgaa gcaatgaaaa ataatgctga atcgaataat
     4381 aatcctgtaa gtgcaattca gcaaaaagtt caacaagata ttgaagaacg taaaaatgct
     4441 atgcacggtc aagctaagtc tgctgaagaa ttaattaatc agaagcgaca agaagctaaa
     4501 tacacgcctg aagcaatgaa tcgtgaggaa atgttaagga aacgtgtaga agggcgtaca
     4561 ggagctaata cggacgaaaa agaagcgttg accaaagaaa gaatccaaga agctaaaaac
     4621 tcaaataccg gattagaaaa attggtcaaa gaaaatctac aaaattctac aagtagtcaa
     4681 ggtggccgat cagtagatgt ccgagaaaat attcaaggtt cattgaatgg tcatgtcgga
     4741 cggaatgttg atgtaagaga gaatttacaa agctcttcaa atggtcaagg tactaagaca
     4801 attgatgttc gagaaaatgt acaaaattct acaagtagtc aagggtttaa atcaatggat
     4861 gtaagagaga atgtacaaaa ttctacaagt agtcaagggt ttaaatcaat ggatgtaaga
     4921 gagaatgtac aaagttctac aagtagtcaa ggattcaaaa cagtagatgt tcgggagaac
     4981 gttcaaaaag atagtggaga aatgaaagaa aaaacacaaa aaatcaatat cgttgaagac
     5041 agaaagtcag cgaaaaaatt tgattcaaat catgaaacag tgattattga tagtgaaatc
     5101 cgtgaaaatg ataagggatc aaaaccaaga cgaagattta cctatgaaga caacgagtta
     5161 ttcagagata cacttaatga tcctaatccg cttttcgata atctattaaa aaaataaaag
     5221 ggggaattgt catgaaatta attctaaaga ttagtacgca tgatttctta gaacttgacg
     5281 aattatgtga atcagtaaag aacgcaacaa atgaaaaaat cacggtcact aattatattg
     5341 aactgatgat tcaagaagaa ttaaagatga aacatgagat aaaaaacaac ttgaaatatt
     5401 gttatctaga aaaaagtgaa gagataatcc atgaattaaa tggcttttaa aaattgtatt
     5461 tgacatgaat ttacgacaag gaattagtgg ggattaagcg attattctct tccactttag
     5521 agaaataatg ggttaaaaag ccagaatacg tagagcaata ttgacaacct ataaaggagc
     5581 tattgttgaa aattgaagta acaaaaagat aaagggaggt ttacatctat cagattaaaa
     5641 gtgatagtac acccatgaaa cctgcaaaag agttgaacct aatgtatatc ggtttaactc
     5701 tttttatttg caaattaaaa aaatatcacc gaagtgacga atgaaactat gaccaaatta
     5761 agcaagaaaa tatatcttgc aaataaagta gtataaaaag ata
//
LOCUS       DAFLVO010000118         5779 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.121, whole genome shotgun sequence.
ACCESSION   DAFLVO010000118 DAFLVO010000000
VERSION     DAFLVO010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5779
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.121"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..813
                     /locus_tag="L1U99_002712"
     CDS             <1..813
                     /locus_tag="L1U99_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HBN1213220.1"
                     /translation="KKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSD
                     NGQIKLLWKSPLSTEKNGVSSLTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSG
                     DNFIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIES
                     KSLNQDQIIKYANYCGVYPKKIARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHAL
                     ALFGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            807..1229
                     /locus_tag="L1U99_002713"
     CDS             807..1229
                     /locus_tag="L1U99_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213221.1"
                     /translation="MVNKLIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            2363..3331
                     /locus_tag="L1U99_002714"
     CDS             2363..3331
                     /locus_tag="L1U99_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBN1213222.1"
                     /translation="MANEIVKYHHELNTIPLRKFTSVEMNLFFSIISRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGIA
                     NFSKEDFHELLDIPKSYRESDINKKIIKPIRQELTAIFKGLTIQKRYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKEPTSLQEKIKEQKRKLELL
                     QQLAELERKQNTPSKKINKQIADNNSDITPEFKENLLDNLQNLFKE"
     gene            3341..3829
                     /locus_tag="L1U99_002715"
     CDS             3341..3829
                     /locus_tag="L1U99_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBN1213223.1"
                     /translation="MTDKTIKELADILGVSKDKVKYQLRKLPSNFTYKKGNITYLKKE
                     AVTTITKVLSGNESGNLPSELPDSLPTDYLLKEIETKNNHIEEKDRQIEKLQIALETQ
                     QKLLDQQQQLTLQANQQIKKLHEQLQLTYAEESSEKEPLSVTEETQKGQNKEKKWWQF
                     WQ"
     gene            4125..4406
                     /locus_tag="L1U99_002716"
     CDS             4125..4406
                     /locus_tag="L1U99_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213224.1"
                     /translation="MDILVRNIDPKVISEIDRRCQELTTKTGKKWSRNAYLKVLIEND
                     FDQALRHYKKDQFDLLLEKFIDIQAKNTETLNDYVHTNNQLIETLIGGI"
     gene            4408..4824
                     /locus_tag="L1U99_002717"
     CDS             4408..4824
                     /locus_tag="L1U99_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213225.1"
                     /translation="MRKTSVQKHVTLYPSHIDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPNTNTTTTSNQAKLNAMGKEISIMSEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSRNFDPTNFLKR"
     gene            5438..>5779
                     /locus_tag="L1U99_002718"
     CDS             5438..>5779
                     /locus_tag="L1U99_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HBN1213226.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTV"
BASE COUNT         2155 a          981 c          947 g         1696 t
ORIGIN      
        1 aaaaaaaata caaatggaga atattcagga agtatttcac aatttttagc aaaagaactt
       61 caaaatctag tagatagtaa tataacagat acaaccttat tttttcaaga taatagcatt
      121 tattattccg ataatggaca aattaaacta ctttggaaat cacctttaag tacagaaaaa
      181 aatggtgttt cttcccttac agaaaaaaat gatcttatat ccgtaaatat aaaaaataaa
      241 attaaaaatt tttctaaaaa acaaaatttt cctgcggtta aacgtgtaaa aagtgtctcc
      301 tccggagata actttattat gattaattgg cgtatagcag aaacccaaac aagttttccg
      361 tggtgcgctg cttacgtaga agctgctatc ttatgtaaca aaacagatgt acgtgctact
      421 tcagctagag ccattatgca ttatacctat cctaatttaa acaacagtca aattgaatca
      481 aaaagtctta atcaagatca aataataaaa tatgcaaatt actgtggtgt ttatcctaaa
      541 aaaatagcac gaatactaaa cctttcagag gtccaaacac aactaagaaa aggaaatgcc
      601 atttatatgg gaactgctgg ttatggaaat tatagtaaca gccgtcatgc acttgcatta
      661 tttgggtggg tcaatcaagg tggttatcaa acttactatg tgtggaatcc ttggtataac
      721 tacccaactg taataagtgc aaatgcagga ccagttacaa ttcctgtacc tggaggtggt
      781 tttacttggg acaataccat tacaaattgg taaataaact cattgcttta gttatgggtc
      841 tagtgttagt tcttttctta actagttgtt caaaaaaaca agaaatacaa aagactgatc
      901 tgattccttt tctaggaact tggcaaacta aagatcattc agaacgtcta gtaatcacta
      961 atttaaatac ttcaaaaaat atagaacaat ataccatctt agtaaaagag aacaatcata
     1021 aaattcaaat cattgataaa aatttaaata taaatgaaca agttttcatt tacaaagcaa
     1081 caaataattt actaacactg cgctcgaata aaaaacaatt agattacact tttagtttgg
     1141 attctccaaa aaagctcgta tttattttga caacgaatga tgggacagaa gggacagcta
     1201 aaccaattga attttttaaa gctgattgat gaatagttgt ttgatattac aaaacaataa
     1261 tttcaccgaa ggtgaaacaa gcgaaacttt acaaaaagtg gctagcattt gctagccttt
     1321 tttgtattgt ggagcgtggg ttttgagggg gattcaaggg ggagcttgcg cccctttgac
     1381 aagcggttat ttgcaccaaa tacgtaggta tttggctagc aaatatagag cttgccaagc
     1441 cctttagtgt gttttgtaga aagggacctt atagtcactt tcacattaca aacgatacgt
     1501 ccataggacg tatcaaaagg gtgggactta tgagcaaatt aaagcaaaat ttggctagca
     1561 atccttctaa aaaatacacc tattgatcag agtcaaaata aatcagtttt cgagtgagcg
     1621 aatccaaatt tgcaactctg aagctttgca aatgagtgtg ccggcttccg taaaagtcta
     1681 ggtaacatta gtcgatatat acatagggct ctaatttgcg ttttaaggcg ttttaaacgt
     1741 tctggtatgt aattatacca aagcgacttt aaaacgcctt aaaacgaatt ttagaggttc
     1801 tgtagaacgt tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg ctttaaaaac
     1861 aagataaggg attttatcta gacttgtctt aaaacgccgt agatgagcgc tcagagcttc
     1921 taaaaggact ccttacgaac tgtttttaag caaaggagcc tttaggcgac tgcgcagttt
     1981 aatgtgagag cgtagcgatc acacctttaa agcgaccgta gggagcagat tcccagttta
     2041 ggaaatttcg cgaacctgtt tggagaaaaa aagtaggaaa attttaggcg ggaaattttg
     2101 cccccctctt ttataatctc ttttataacc tctttttaaa cctctttacc gtcggctgta
     2161 tccttactct cccaaggtgt gcagaatctt ttaggggtct ttttgtctgt ttttaggggt
     2221 ctttttgtct gtttttaggg gtctttttgt ctgtttttag gggtcttttt gtctgttttt
     2281 aggggtcttt aattaggggg ttgaccccca ttagaaagct ctttataatt ttgttaagta
     2341 gttaatcttg aaggaggatt ttatggcaaa tgaaattgtg aaataccacc atgaattaaa
     2401 tacgattcct ttacgcaaat ttacgtcagt agaaatgaat ttattcttct ctataatatc
     2461 tagaatgcgt gatgtaggcg ataaaaaagt acaatttaca ttcgaacaat taaaagattt
     2521 aagcaattat aaagcaactg caaatgttcg attcatagat gatttagaaa caacgtatga
     2581 caaattaatg gatttacgtt ttggtagaag aagtgctgac ggtttgcaac gtgaacgatt
     2641 tgttttattt aatcaattta aaatcgatgg aaaagctgat attccttttg ctgaaataca
     2701 agtccatgag aaagccttac ccttacttaa taatcttgaa gaatgggttc gatattctct
     2761 ccaacaattc aatgaattag aaagcagtta ttccaaaacc atgtttagat tattaaaaca
     2821 atacagaacc aaaggaattg ccaatttttc aaaagaagac tttcatgaat tacttgatat
     2881 ccctaaaagt tatagagaaa gtgatataaa taaaaaaatt ataaagccta ttcgccaaga
     2941 actaaccgca atcttcaaag gtttgacaat ccaaaagaga tacggaaaag gacggggaaa
     3001 gcctgtcatt ggctatcaat ttacatttaa acctgagata aaaaaatcag acgactttaa
     3061 caaacatgct ccaaccaaag aagaacaaaa taaagctttg gaactagcta atcaacaggt
     3121 tcaatctgaa aaagaaccta cttcattaca agaaaaaatc aaagaacaaa aacgaaaatt
     3181 agaactttta caacagttag cagaattaga aagaaaacaa aataccccaa gtaagaaaat
     3241 taacaaacaa atagcagata acaattccga tattacccca gaatttaaag aaaacttact
     3301 agataatctc caaaacttat ttaaagaata aggggttttt atgacagata aaactatcaa
     3361 agaattagca gatattctag gtgtttcaaa agataaagtg aagtatcaac tgaggaaatt
     3421 acctagtaat tttacctaca aaaaaggaaa tattacctac ctgaaaaaag aagcagtaac
     3481 aacaattaca aaggttttat caggtaatga atcgggtaac ttacctagtg aattacccga
     3541 ttcattacct accgattacc tactcaagga gattgaaact aagaataatc atattgaaga
     3601 aaaagatagg caaattgaaa aacttcaaat agctttagaa acgcagcaaa aattactcga
     3661 ccagcaacaa caactcaccc tacaagccaa tcaacaaatc aaaaaacttc acgaacaact
     3721 ccagctaacc tatgcagaag aatcttcaga aaaagaaccc ctttctgtta ctgaagaaac
     3781 tcaaaaagga caaaacaagg agaaaaaatg gtggcaattc tggcaataac ccaacaattt
     3841 ttattcataa aaattgttgg gttactttct ttttttgctt ttacaagcat agcgacatga
     3901 tctcacgtcg ctatttttta aagagcataa ggaaacgcgg tatcactttc ttacgaaagg
     3961 tgctaggtag gctgtgccta ccacgtttct aagaaaaaaa tttgctatca ctttttcgtc
     4021 attgtggata gcttatgtat agtgtttcgg caaaaaacag ctatacaaat actatatttg
     4081 tatgatatac ataaattata cacaaatgcg aaaggaattc ttctatggac attttagttc
     4141 ggaatattga tccaaaagtt atttcagaaa tagatagacg ttgccaagaa ctcacaacaa
     4201 aaactggcaa aaaatggagc cgtaatgcgt acctaaaagt tctaatcgaa aacgattttg
     4261 accaggcact taggcattac aaaaaagatc aattcgattt attactcgaa aaatttatcg
     4321 atatacaagc aaaaaatact gaaacattga acgactatgt tcatacaaac aaccaactca
     4381 ttgaaacact tatcggagga atataacatg agaaaaactt ctgttcaaaa acacgttacc
     4441 ctttatccca gtcacattga cgttttagat tccatcatcg aaaaaaatcc agatatcaat
     4501 aactactcgg aagccattcg ttttctatgt atgagttatg aacctaatac taatacgaca
     4561 actaccagca accaagcaaa actaaatgcg atgggaaaag aaatttctat tatgtccgaa
     4621 atcattgcag aatttgctga tttatatcta aaagatactg gtgttcttat cggtacaaat
     4681 tctaaagtat atcaagaagt gaaagaaaaa attgaaaatc aactcaatcc ctcccgacga
     4741 aatcaaccca aaaatcgtca aaaagaaacc aatcaaacat tcacttctag aaattttgac
     4801 ccaacaaact ttctaaaaag atgaaaaaga aaccgaaaat tttttctatt tctcagtttc
     4861 ttttttaggg ggcagtcttc cagcaagatt tgcaagttac cggtaacttg cacaaaaaaa
     4921 gaaaaatccg cttgtgcgaa tccttctttt tgcattttgg ggcgctgccc caatctccaa
     4981 atatcggtta tttaatagcg tggtaactca aaaaaataga acgtactctg aaataaaaaa
     5041 agactgctct aacgagcagc caataaaaaa taatgagcgt ttattcttga aaaagcagcg
     5101 cgcttatgaa gcgctgccaa aaatttacca tattttatga aaaataacaa gtttctaaaa
     5161 aggaatcggt taagattcac aaagaatcgt aaacagacaa tagcggaaaa tcaagcttcc
     5221 gaacgtacct tttagctaga ccaatgaaaa atcacaaagt gagcggctgg atcggttggt
     5281 agaggggcta cttggcatag tacacattat gttaactaac gctataaata acgattatgt
     5341 tcccaaaaca atattttatg aactataaca aaaatttgtt atcgcatatt gtatatttta
     5401 attataggtg tataccactt aaatttaaca caaaggcgtg attattttga aacccaaaaa
     5461 gaaaatttat ctaggtctcc tcttttcctt gatgattgga atttttagta taggaattac
     5521 aaatacctat gcttcagaaa attctaattt caatatcaac tcccaaccaa ttgaagaaca
     5581 agcaattaat tttgcgaaaa ctgattttga acactccata acttcaattc ttttaatgga
     5641 aaataacacc gaaactgata ttaactatac tcttggttcg ccatttaaaa tgctcgatgg
     5701 agaaaatacg gcaaatagtt ctattttctt tccagtattt tcagacgctg ataatacgat
     5761 taaatatatt tataccgtc
//
LOCUS       DAFLVO010000119         5678 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.122, whole genome shotgun sequence.
ACCESSION   DAFLVO010000119 DAFLVO010000000
VERSION     DAFLVO010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5678
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.122"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(190..648)
                     /locus_tag="L1U99_002719"
     CDS             complement(190..648)
                     /locus_tag="L1U99_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1213227.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(661..1992)
                     /locus_tag="L1U99_002720"
     CDS             complement(661..1992)
                     /locus_tag="L1U99_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HBN1213228.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(2003..3445)
                     /locus_tag="L1U99_002721"
     CDS             complement(2003..3445)
                     /locus_tag="L1U99_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1213229.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(3432..4196)
                     /locus_tag="L1U99_002722"
     CDS             complement(3432..4196)
                     /locus_tag="L1U99_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HBN1213230.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(4300..5175)
                     /locus_tag="L1U99_002723"
     CDS             complement(4300..5175)
                     /locus_tag="L1U99_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1213231.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(5430..5514)
                     /locus_tag="L1U99_002724"
     tRNA            complement(5430..5514)
                     /locus_tag="L1U99_002724"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5478..5480),aa:Leu,seq:caa)
     gene            complement(5532..5603)
                     /locus_tag="L1U99_002725"
     tRNA            complement(5532..5603)
                     /locus_tag="L1U99_002725"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5569..5571),aa:Gln,seq:ttg)
     gene            complement(5620..5677)
                     /locus_tag="L1U99_002726"
     tRNA            complement(5620..5677)
                     /locus_tag="L1U99_002726"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5650..5652),aa:His,seq:gtg)
BASE COUNT         1747 a         1197 c          845 g         1889 t
ORIGIN      
        1 tctcttaaat aatcaaattt atttttaaga atcctgaaaa taagttttct aaatcatagg
       61 agcaacaaaa aaattcgata attaacaaaa atcaaaatga ttaaatctag tgattgaaac
      121 atatcatttc aaaaaaattt tgtaaattca cccataaata tcaccctatt taactttttt
      181 catcgtacac taaaattcaa aacaactatc tttaatcttt acttcttggt tttgttttaa
      241 taaatttcct tcaaaaatgc ctggagaaac tacaatgatc accgtatctt tttgtgcttg
      301 ctccaacttc ttcaaatcta taatagctaa cagtgtccct tcttttacct cctggttact
      361 ttcaacccgt atctgaaacg gacttccttc gagttcaact gtatctaaac ccatatggat
      421 cagtattttt ctgccagatt cactttcgat cgttatggca tgtcgggtag gaaatatatt
      481 atcgattatt cctttaactg gcgcatggat atatccatca tgattcgtta tagcgtatcc
      541 aactcctatc atttttgaag aaaagacctc gtcttttact gctgttaatg gaataatttg
      601 accactagct acagctttta gaatgtttct tgttttaaag aaatgcactt tttatcacct
      661 ctactttaat gctggccaat attttttgtt tactttgatc atttcatcta gtattttttt
      721 tgcgactctg gcatttggta cggtttgatt caatgtaaat gcttgtaaag ctttttgata
      781 agaaccttca aagtaagcat ctactagtaa cttctctact gcaacttgtg cctccatcaa
      841 tcctttatga aaatcactga ttggttttct tagtgtaatt ggctccacac cagttgcacc
      901 aacatatgcc ggtatttcaa caactgcatc tgaccgtaga ttcggaatcg ccccttgatt
      961 aggaacgatt agcataaagc gacgacgatc atcattcaac aaggaaatag ctatatcgac
     1021 gatatattgt ccatgctccc caaaattaaa gttcaatact tcttccacaa taccgcggcg
     1081 tattttatca gccatttctt tggtattttt ctctcgtcca tccatgacca tattagcacg
     1141 tgtatactct ttgtcagtat gctcaacgac catatcagga tataagtaat actctaagta
     1201 attattcggg atattacttg gaaaattttt cgtgatgact gacatcattt gaaaggtttt
     1261 ttgccaagtt ttatctccta tattaaaatc ggcgacttgc atttcttttg ttattagttt
     1321 ttcaataatc tctggcataa tttctcgttg caattcttta tcataaatcg atgtatacca
     1381 gccaaagtgg tttaaaccat aatacgtaac gatccaattc ttacgatcat aaccgtaatt
     1441 cactgcaatc gtttcttcaa ttgaaatagt catatcacag gcattaatca tttttacatt
     1501 cggatattta cgacgaacag cttcagaaac gatcgactct ggatttgtat aattcaaaat
     1561 ccatgctttg ggggcatagt cttgtatatg atcgacaatt tccaataaac ctttgattga
     1621 gcgcatccca taagcaaatc ctccgagtcc acacgtttct tgtcctacta atccatgttt
     1681 aagtggaatc ttttcgtcct tttctcgcat ctccaatcct ccaacacgaa tttgtgagaa
     1741 aacaaaatcg catcctgtaa aagcaagctt tggatcatcc gttgcacgaa tgcgaatatt
     1801 tgaaaaacct tttcttttca gcataaattt aacaatcaag tacatatcca tatttctttc
     1861 ttcatcaata tcatataaac gtatttcaga taatggcaac cgtttttcat tgttcaaaat
     1921 ggcttgaacg attcctggtg tatacgtact cccgcctcca gctatagtga taatctgttt
     1981 tttcatcatc atcttttcct ttctattctt ctaataattt attgaattct gccataacat
     2041 aagtcacttc taagccgatg ataatttgat aatttttttc agttggttta atgatcccgc
     2101 ttatccctaa ttgcttgatt cgctgttcct cgaccatggt gggatccact acctctaccc
     2161 gtaggcgtgt attacaacta tagacatcca ggatattggc ttttcctcca aacgcttgta
     2221 gcatttttgt tgccatatat tcataatttt tacttgctaa ccctaactct gtttcttcta
     2281 aggttacttc attgccaaac tctgccttag cttcacgtcc taatgtctga atgtttctct
     2341 tattgatcaa ataataaaaa gtaacgtaat acaaggcaaa aaagaaaatt ccgattggaa
     2401 gaatcaaaat agcattggta gcgattcgaa aattgatgag ataatcaaca atacatgctc
     2461 cgaatgtaaa accaattcgt atattgaata agtaacagac aatccctgct aaaccggcaa
     2521 aaagtgcatg gatcacgtac aacataggag aaagaaacat gaaactaaat tcaacaggct
     2581 cagtgatatt tgcaataaat gaagttcctg caccgcttcc catgattcct ttgaccatct
     2641 ctttattttc tttataagct gctttataga tagctagaca tatagctggt ataccaaaca
     2701 tcattactac aaaaaaaact gataaaaaca gtccagcctg aggatctccg ttgataaagc
     2761 gtgtcatctc tcctctgaaa acttccttgc taggagatgt atagcttcct aaatcgtaat
     2821 aaatatacgt attcaacaca tggtgcagtc caaaggggat cagcaaacga ttcaaaaaca
     2881 taaatatccc cacacctaat gctcccatat caacgagcag ttttgcaaaa ttatcaatcc
     2941 caatttggat gagcggccag ataaagccca aaaaaacagc tgcgattgtt tgtagaatca
     3001 tcaccatagt caatgggaat ttttcgcccg caaaataaga aaaaactact ggtaattttt
     3061 gttctttaaa gcgattatac gtccatgccg ctactaaacc ggaaataatt ccaccaaaaa
     3121 tccccatatt cacttctggg tccataattt ctaagccttt tttcaaggta gcaatcgcta
     3181 aaaaaccagt aagtgcaggt attcctttgt ccttattttt gacaaaaccg attgcaactc
     3241 ctatagcaaa taagatatcc aagtttccaa aaacggcatt tccagctgca ccaattactg
     3301 ggatgttcag catatcgtca gctgataaac gcatgatcaa tcccgctaat ggcatcgctg
     3361 caactggaag tagcatcgct cttccaagct tctgcacatt tgatttaaca ttcattttta
     3421 ttcctcctct attaaatatc ctcatatgtt actaactcaa tcaaaggatc atttttcact
     3481 ttttgagcaa atgctgaatg aattaaaaat tcgacttggt gggtacgagg atacacaaaa
     3541 cttgaaccat ttaacaattc ctgatccaaa tacgctgcgt gacacatgac ttcgatcgtt
     3601 ttatcttctc tcaatatcat gagtaaactt gccaaatatt cttccacact cgtattgatt
     3661 tgtcgttttt tttcatcagt ttctcctacg acatcgaaac aaggctcaaa ataatcgaca
     3721 tgacgaactt catcttttcg ttcaaagttg ctccgaaccg gcaaatcata tttttttgct
     3781 aatgtaacaa ctacctcctg attttcatcc aaagtatgag tatgatgatg actgtctaaa
     3841 tgagttggta tgatccccgc atgataaatt ttttgaatct gagcattcca ttcctgatac
     3901 agttgatctt tgtcaatgtt aaatggatgc tgataataag ataaggatct gaactctccg
     3961 ctttcgataa gagtatcgac agttttgagg agtggtttgc cacacgtcaa tgttaaatgg
     4021 actcctacac ctagcctagg catttccttt cttagtttca cagcatgctc gaaacccggc
     4081 atatttgcca tcaatgtagt tgatgtcaaa attcctcgct gataagcatc cataatccca
     4141 taattcacac catggctata gccaaaatca tccgaattaa aaatcacttt tcccatttca
     4201 ttctccttct tttttctact aaaataggcg caaccaaata atcatagtcc atttactatg
     4261 tgtcatttgg ttgcgcctat agatagttac gcccttattt taatagattc ttgctagatg
     4321 aattgccaaa tagatgattt cattttcttg aatggcaagt tgaaattgct gttcgatgat
     4381 atctttaatc tttagtgctg tacaatacgc tttgctatgt ttaaatgttt cagtaaaaaa
     4441 accaatattt tctactggcg tttcttcctg ataaatcaag cgtttaacca ggaatttgat
     4501 atgaaccatt aagcgatgat aagtcagtga ttctttatca taaacgtttg aataggattt
     4561 ttctagatgg gacaaaatcg tggtcgtcat ttctactatt tttaagctct ttaaactatt
     4621 aggctctcct agctcagcat taatgatatg catagtgatg aatcctactt catttgaccc
     4681 taactcggtt tgatatcgat gattgattcg ctcgaccact tctactgcta tatcatattc
     4741 atttggataa aggaatctca tttctggcaa cataattgct gtgacatctc tatcttctct
     4801 ttttcgttga atagcaaaat aaatatgatc tgtcaatgta atatagatat ttgaatctaa
     4861 tggagaggag atcctagctg ttatcagttc aatcacttct tccgcaaaat ccataaattc
     4921 gattggaatc tgcgagacta tctcactgaa tcgtttgatc ttttctttag aatctaatac
     4981 aaataatttg tcagcatcct caacatcaaa tggcttactc actttagcag aaaagccaat
     5041 ccctttcccc atcgcaattt tttctattcc atcgtcatcg atcaatacag cattatgatt
     5101 cagctttttc atcacataca ccgttaattc acctcctcta tatgataaaa caaaacaact
     5161 tgcagactcc ttcatacata tttttgtctc caaacaattt ttaaagacaa aaaacgacct
     5221 aagaaagaac cctttcttag gtcgtgccta attgaatagt agcaccctac ataatttaca
     5281 aaaatagttt aacacataat aaaagcgtta tcaatatctt ttttactcgt tttatgataa
     5341 tacttgtatc gaattgattt ggaggtaatt acataaaaac aaaaaaaata tagcaactct
     5401 ctataagaaa gttgctatat tgataattat accggcggcc ggggtcgaac cggcacgtcc
     5461 tcaacggaca ctggattttg agtccagcgc gtctgccaat tccgccacgc cggcaaattt
     5521 aaaaataata actggggtag ctggattcga accaacgcat gagggagtca aagtcccttg
     5581 ccttaccgct tggctatacc ccaagaataa agggcgaatg atgggaatcg aacccacgaa
     5641 tgccggagcc acaatccggt gcgttaacca cttcgcca
//
LOCUS       DAFLVO010000120         5651 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.123, whole genome shotgun sequence.
ACCESSION   DAFLVO010000120 DAFLVO010000000
VERSION     DAFLVO010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5651
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.123"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            211..264
                     /locus_tag="L1U99_002727"
                     /pseudo
     CDS             211..264
                     /locus_tag="L1U99_002727"
                     /inference="COORDINATES: protein motif:HMM:NF019230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            268..867
                     /locus_tag="L1U99_002728"
     CDS             268..867
                     /locus_tag="L1U99_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBN1213232.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQIGKSIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGFLGSLVPFLLHSNIVSMGLSGGIFGWIALFAIAYIRFDSKKHLLLSVFVLLIIGIL
                     LVSTFESGEANVLSHVIGFVCGMILGFILKNVSLIKQKN"
     gene            883..1359
                     /locus_tag="L1U99_002729"
     CDS             883..1359
                     /locus_tag="L1U99_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213233.1"
                     /translation="MPKRKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMYE
                     QREALRERIHYFDDIHTKIYEARTNHEDESKLGLAQQRILEWLNTNTDQEPLRVISNL
                     FEFGTKHWFNAVEKDADLQEAFDTLSKDSKSMRDLLITYLNEHEFEQTKTKKKNKE"
     gene            1376..2278
                     /locus_tag="L1U99_002730"
     CDS             1376..2278
                     /locus_tag="L1U99_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213234.1"
                     /translation="MLLTLLGYLCLILAFFGAIAIIIGQFQTNNPIMRNIGIGIVIVT
                     FIVFNATKIFGSNDKQFGISGVNNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDGK
                     KASDDVLATIKPSQSQFEVFYTVKENSPVHKLTLVFNVDGEEYYKDVKINKTSTKKII
                     ESAKKEVATEESTTESSSTVEAELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQMINVTLFNSVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGADLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            2351..2542
                     /locus_tag="L1U99_002731"
     CDS             2351..2542
                     /locus_tag="L1U99_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213235.1"
                     /translation="MVVNKEKVRKYVTLKIASVKYLEKRAKEEERARGKKVTVSELLE
                     ELIENDQTIRRAFTNRSIR"
     gene            2706..3293
                     /locus_tag="L1U99_002732"
     CDS             2706..3293
                     /locus_tag="L1U99_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213236.1"
                     /translation="MENNNDIRHFSIGERVTTVSELSKDYRDKEGTIISLNKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNNGSHSIEKAILVYPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITSKEAKIEDVLTVRELQSLIEYRNKQITNPEYLRKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDTFKKIYLKEIKKD"
     gene            3293..4192
                     /locus_tag="L1U99_002733"
     CDS             3293..4192
                     /locus_tag="L1U99_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBN1213237.1"
                     /translation="MWTVTLPFQPVSAPRPSARRNAADETNDVAEKRISTYYDKKYLD
                     YLKKIKSFIEDQDLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLD
                     NLVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGD
                     IWEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVM
                     NAPMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVV
                     GLIAFKYNTFEKSKTNVRLQEMG"
     gene            4192..5106
                     /locus_tag="L1U99_002734"
     CDS             4192..5106
                     /locus_tag="L1U99_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213238.1"
                     /translation="MNNNEKILHVLDSFEIIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKNAMELNEERRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPSNSGIGIVLKAIDEEEIEAFIPPEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCESYGVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     EARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNATNRLEKAVSELDA
                     YYREHYLQAGGMPRNTKANISRYIKKAE"
     gene            5158..5373
                     /locus_tag="L1U99_002735"
     CDS             5158..5373
                     /locus_tag="L1U99_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213239.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NSVVLKQFWLNNFSYKDFIKEKANTLY"
BASE COUNT         2144 a          711 c         1148 g         1648 t
ORIGIN      
        1 ctttaattga aaaatatcct tttttaaaaa gcaaaaataa aattcaaagg ttaattcgtc
       61 aaggcgatat tcaagctaaa gaacctgttt tgacaaccaa tgatttggct aaaataaatc
      121 ttcataaaca aattattgaa gactttgaaa aaaatctttc aacaactgaa attttaaaaa
      181 aatacaatat tccgagagga aagctaacat cgactctttt tagagaatat ggagaatcgg
      241 cagttactaa agcaaaggaa gtagcgaatg agagaaaaaa acaaaaatag tagtcgatac
      301 ctagtagcga ctgtagtttt tgtttgtgta ttgattttcc tgtttgattt tttgcagatt
      361 ggaaaaagca taattggaaa tacattgagt gcaaaggaaa tggttgcttt aggtggtttg
      421 tatgaaggac acttgttccc gaatatattc atttctatcg tttctcatat taacttgtac
      481 catttaattt ctaatttatt gttcttagta gttcttgaag aagcactgaa tgatcagtat
      541 gagtggttaa cattattgat cgttttaatc atatcaggat ttctaggaag cttagttcct
      601 tttctgctac acagcaacat cgtaagtatg gggcttagtg gaggtatttt tggatggatt
      661 gctttatttg cgattgcata catccgtttt gatagcaaga aacatttatt actaagtgtt
      721 tttgtattat tgataatcgg cattttattg gtatctactt ttgaatcagg cgaggcaaat
      781 gtcttgtcac atgtaatcgg atttgtctgt ggaatgatct tgggatttat tctaaagaac
      841 gtttcattga tcaaacaaaa gaattaaaag ggagtgctaa aaatgccaaa aagaaaagaa
      901 aagaaaattc cagtgttttt gtctgtctca gaaatgttat cacttcaaat actgttaaga
      961 aaaaagattg aaacaataga cgaagaagtt agaaataaaa gggctatgta cgaacaacgt
     1021 gaagcgctaa gagaacgaat ccactatttt gatgatatac acactaaaat ctatgaagca
     1081 cgtacaaatc acgaagacga aagtaaatta ggattagctc aacaacggat acttgaatgg
     1141 cttaatacga atactgatca agaaccgtta agagtgatta gtaatctttt tgaatttgga
     1201 acgaagcatt ggtttaatgc tgtagagaag gatgctgact tacaagaagc gtttgatacg
     1261 ctaagtaagg atagcaaatc catgcgagat ttattgatta cttatctaaa tgagcatgag
     1321 tttgaacaaa cgaaaaccaa aaagaaaaat aaagaataga aagttgtgat gaatcatgct
     1381 attaaccctg ttaggttatt tatgtttaat tcttgctttt tttggggcaa tcgctataat
     1441 tattggtcaa tttcaaacaa ataatccgat tatgcgtaac ataggcattg gaattgtgat
     1501 tgtaaccttt attgtgttta atgccactaa gatttttgga agtaacgata aacaatttgg
     1561 tatatcggga gttaataata gttatgctcc agattctttg ggaagggtag taatagatgg
     1621 aacatttgaa aatgtaacga gttataaaaa tgtttcgctg acagtgaagg aagatggcaa
     1681 gaaagcatca gacgacgttc tcgctactat taagccgtct caatcacaat ttgaagtgtt
     1741 ttatacagtt aaagagaata gccctgtaca caagctgaca ttggttttta acgttgatgg
     1801 agaagaatac tataaagatg taaaaataaa taaaacatca acgaaaaaga ttatcgaatc
     1861 agcgaaaaaa gaagtagcta cagaagaaag tacaactgaa tcaagttcta ctgtcgaagc
     1921 ggaactacca gataaaattg attttgatcc tgaaaaagtc aaatcgtttg aatctgtttc
     1981 tggttctatg gctgatcggt ttaacactga agtcttcaaa gctatcaaaa ctgttaaatt
     2041 ggatactgaa aagcaaatga ttaatgttac cttattcaat tcagttgaat ctatggatca
     2101 ggataaaaaa gttacggttg caagagaact aggaaaaaga gtaattggtt tgtatcgtgg
     2161 tactgctaaa ccagattcag acggtgcaga tttgccagtt catgtagttt atgaagacgg
     2221 taaagttttt ggagattcta cagcaaacga agcattaacg attaaattgg ctaaatagcc
     2281 agaaagttat aataaacaaa tggtgtcaca ccaataatat ataggtgtga caccttggag
     2341 atgatagctg atggtagtaa ataaagaaaa agttagaaag tatgtgactt taaaaatagc
     2401 ttctgttaaa tatttagaaa agcgagctaa agaagaagaa agagcaagag gtaagaaagt
     2461 aacagtttca gagttgttag aagaattgat cgagaatgat caaacaataa gacgtgcatt
     2521 tactaatagg tctatcagat aacaatataa ttaataaaaa agaaagagtg atttggtctt
     2581 agactaaatc actcttttta tataaagttt ctttacactc attccgaata atgttaaaat
     2641 tctttatatg atatatagtt ccttgtcaga ggaagagata accagcaata ttggagggat
     2701 aataagtgga aaacaataat gatattagac attttagcat tggggaaaga gttacaacag
     2761 taagtgaatt atcaaaggat tatagagata aagagggaac gattatttct cttaataaga
     2821 atcgaagagg cgtttggcaa tatgttgttg atttaggtga tggcgttaca gttgagtgta
     2881 aagatagtca actgatcaga aataatggca gtcattccat tgaaaaagca attcttgtat
     2941 acccaaaagt atcaagtaag atcatgaatg actggttgct tggaaaattt ggtgagtaca
     3001 ataaaaaaga aatcgcagaa gtgatcggca aatcttatcc aacagtatta gggtatctaa
     3061 aaaagataac gagtaaagaa gcaaaaattg aggatgtttt aacagtaaga gagcttcaat
     3121 cattaatcga gtatcggaat aaacaaataa caaatcctga gtaccttaga aaagaagatg
     3181 gtctattgaa acaattggaa caagtaaata aaatccggaa gatgcaaaag gtagctcctt
     3241 taagccttga tacctttaaa aaaatctatt tgaaagagat caaaaaagac taatgtggac
     3301 tgtaacttta ccgttccaac ctgtatctgc accaagacca agtgcaagaa ggaatgctgc
     3361 tgatgaaact aatgacgtag cagagaaaag gatttcaacc tactatgata aaaagtatct
     3421 tgattatttg aaaaaaataa agagctttat cgaagatcaa gatttattag atgatgaatt
     3481 ttactcgatt gtaaatgatc ctatgggcgc aattatggaa gtggactttt actaccagat
     3541 accaaaaagc tataaaaaag tctataacat tatgaagaca acagcgccag atttagataa
     3601 tttagtaaaa agtgctatgg atggtatttt taacatctca gctatacgag atagccatat
     3661 cacaggctta attgctttta aatataatgt ggcgaacgaa ggaaaaacag ttgtgaggat
     3721 caaacgatat tcagaatttg agtgggatac ttctgaagga ttgaacggag atatatggga
     3781 agctacattt gattttaaac cagtagcaac gccaagacca aagtctaaat ttagaggaaa
     3841 tgggattatc acttactatc caaaagagta caacgactat ttggaaaata tcaagaatac
     3901 gcttaaagag aaagatttgg taaatgatca actgaaaaag gtaatgaatg ctcctatggg
     3961 ggttatagct cagatagatt atttttacca agtgagaaaa gataagaaaa agcttgattc
     4021 actgatgcgt acttcacagc cggatattga taatttagtc aaaggaacat tggacggaat
     4081 ttttaacaag gaaataggca tcaaagatag cagggttgta gggttaattg cttttaaata
     4141 caatactttt gaaaagtcga aaacaaacgt gagactacag gagatgggct gatgaataat
     4201 aatgaaaaaa ttcttcatgt acttgatagc tttgaaataa ttcaagaaga actaaaaaaa
     4261 tatcgggatg ttttggaaca aagatatgat tttgtcaatc agcaaaagag taatcacatg
     4321 gatttcattc tcaatatgaa tgacttgaag aagaaattag ttgaacgaaa agaacaagaa
     4381 aagttgatca aagcttactt tgaactcggt gaaaaagaag ttaaaaatgc aatggaactg
     4441 aatgaagagc gcagggtttt agatcagctg ttagaacaat tattggtgat gtttcaaaaa
     4501 ggacgaatag atgaggattt aattgaagaa ggattgagaa aatatccttc aaactcaggt
     4561 atcggaatag tgctgaaagc gattgatgaa gaagaaattg aagctttcat accgccagag
     4621 gattttgaat cggcaatgga atatataaaa tattatagcc aagggatcac tgcttttaga
     4681 gagtttgatc ctgaagatgt tattcatgac ttgaacaacc taaaagaatg gtgtgaaagt
     4741 tatggagtcg atgattccgg attggactac ttgatcagta ttatggaaat cgaagaagag
     4801 atgccggata agcctgatcc aacagatatt ttagaattga tccatgaagc tagaaatcca
     4861 attgcctata tttctagagg atatactgta ttggaatact ataagcctta tatatcagcg
     4921 atgaaccatt taagacgtgt attaagggaa aaacgtgaat accgctcagt gttgaatgca
     4981 acgaatagat tagaaaaagc tgtttcagag ctagatgctt attatcgtga acattacctg
     5041 caagcaggtg gtatgccaag aaatacgaaa gcaaatatca gtaggtatat aaaaaaagct
     5101 gagtaggcgg agttagccca taaaatggca aaaggtaacc tgaaaggggc attttgaatg
     5161 aaaagggatg tttttgaatt gtacgtatta gaacgtctag aagacggcat gatggcacaa
     5221 gagataattg atgaaattga tgatatgatc agcagatttg gtcaattgga gttgaatgat
     5281 ggaaacaaaa attcggtagt gctaaaacaa ttttggttga acaatttttc gtataaggat
     5341 tttatcaaag aaaaggcaaa tacattgtac tgactaaatt cacgaggagc agtgatgaga
     5401 gcttattgct aagagcagtt aggctctttt ttgtttgtgt aaaattattt gttttataat
     5461 acacatttat acacaaaaaa atattgacag atagtacaca aatgtggtag gatatatttg
     5521 taagcaagtt agattaacaa gttaaaggaa gagcagttat gaaaaaagaa gaactaatag
     5581 atatatttca aattgttgaa cgagcaaata atatgggaat tatgtttttt gatcgtattt
     5641 ctttaaagat g
//
LOCUS       DAFLVO010000121         5581 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.124, whole genome shotgun sequence.
ACCESSION   DAFLVO010000121 DAFLVO010000000
VERSION     DAFLVO010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5581
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.124"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(1014..1304)
                     /locus_tag="L1U99_002736"
     CDS             complement(1014..1304)
                     /locus_tag="L1U99_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213240.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1706..1942
                     /locus_tag="L1U99_002737"
     CDS             1706..1942
                     /locus_tag="L1U99_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213241.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1949..3901
                     /locus_tag="L1U99_002738"
     CDS             1949..3901
                     /locus_tag="L1U99_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBN1213242.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="L1U99_002739"
     CDS             complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="L1U99_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBN1213243.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(4797..5489)
                     /locus_tag="L1U99_002740"
     CDS             complement(4797..5489)
                     /locus_tag="L1U99_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBN1213244.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSWKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT         1815 a          972 c          903 g         1891 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattta agtagttcag ttttggagta caaaaagtga
     1501 aaatgtaaac ctaaatgagt atcaaattgc aactgaattt gatactcgtt ttttattgtt
     1561 aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag ttaaaatgta tataaaaatg
     1621 cgaacgtgaa ataattattg taggaatgca aattggtgtg ttaaaatggt tacaatttac
     1681 taagcaaaaa ggggtgcatt ttcctatgca atttcttgag ccaaaaaata agaacgctaa
     1741 gtctgtggat tgggaaatat cagagcaagt aagggtgata gttaagcaat acgctgaata
     1801 tgcagagcgt actgaaagcg aagcagtgga tgaattctta ttgaacattt tagacgataa
     1861 gaagtttatt gaatggattg ccaacaagcg aagtaataag cggattgttg aaaaaatggg
     1921 tatcaaagat agagtgggtt gatagacaat gaccaagctt aaaagattag ccacgaagga
     1981 agatgaaatt gtagatgtta aaattccgat ttcaaacgaa gaattaaaag atagggctaa
     2041 acaatatgat ttattaactc caaaacgatt tgcaacaagg tataacaaaa tgttgttctt
     2101 gccaacgtct tttaaatgga acggttctga atatcccatt caatataatt actgcatcaa
     2161 tccgttttgt tgtaattttg ggaaagaaca gcacaaattc aaagatgtaa aagggaaacc
     2221 aagtcgatat aaaatgactg gtagttccaa agataaaggt cataaaggta tgtactgcaa
     2281 tgacaatcct attggcagag gtgtatcgca aaactgtaca gtaacccctt tatctaattg
     2341 gtctgttgtt gaagaaatta aacgccttat agaaatcaat agcatccaag atgttgagcc
     2401 agattatcaa tttcataaag aaggctgctc ggaagaagaa tcaaccccat tcaatgagcc
     2461 gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct caacgctatc aatgtaaggc
     2521 gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa accactactt atcaccaaca
     2581 aaagaacacc attcttccaa tgttcgctaa gatggttgtt ggaagggttt cagtcagtcg
     2641 tacttgtgat attttaggaa ttggagttgg aacctactat cataagctgg agtggctgta
     2701 taggcgttgt ttggagtttt tagaacgata tgagacacaa ccccttcaaa caaagaaatt
     2761 taacgagatg tggcttaata cggacaagat gcactactac ctaaataacg tccgtaagaa
     2821 aggacaaggt tcaaagaaat atacggggtt tgaagacctt aatatgcaaa cgtatatagt
     2881 tgtatctgct gaggtcttat caagatatgt gttccgttct gatgttgcct atgattggaa
     2941 tatttcaatg gatgaattaa atgaagatac aagaaaattc aaagaagacc atctcaatac
     3001 ttttagtcgt aaaaatgata ggttagattg gtcttattat ccacaagaac catccgctaa
     3061 cgatagcgaa aataggaatg cttatcttca cgaattaggg aaaattacta ataggagtag
     3121 atttgtcgat ggtttaaatg ttgatgctcc ttatactaca actgctcact attggttaat
     3181 taaacaaatg gttaatgccg acgaatggcg aatgattagt gatgatgact tctctattag
     3241 aaacgccttt tatagagtat tcacgaaaga attaaggttg agcgatgcac atcattttat
     3301 ttgccaagtt aacaagacga aaagcagaaa acaatgctta aaagaattcg gacaagcaaa
     3361 agcagaactg ctcgattggg gagatatcag aggattcaaa acaaagtttc tacggacttt
     3421 ggcatctcat tatctaactg aattactaac aagtcatcaa ttccacgaag aggctattag
     3481 taaagatgga gaaagatatc gcaaatatgc cgataaccct atcaaacatc cattagccac
     3541 taaggataaa ggattttatt cagttgattg tagaacggat ttatctgctc tggaaccaaa
     3601 cgaaatcgca aagatgctat taaatgttaa tgaccattcg accaatagct ttattcaaca
     3661 gataagacgt tatatatcat ctcttgaaag accattaaca acagctcgtg gtgataagaa
     3721 gagctatatt tacgctaact tcaatccgaa gtatgctcaa tttgcgatta caattctaag
     3781 aacttactac aacttttgtc gcccttttaa atcagcggat aaaaaggttt tgacacctgc
     3841 tcaaagatta gggattacag ataaacaatt tgattggaaa gatataattt atttcaaatg
     3901 acaaaaagag cttggagtaa tcccaagctc ttgtgcttta tctttactgt tcttcttcaa
     3961 ttaacgcacc cgttaactca ataagttttt tctttcatat acatgaaaat agtagttata
     4021 cggattttta tcattcttta tccctttttg ggcaaatacc tcattccatt cctcataatt
     4081 cacttctgga aaaaaagtat ctccttcgaa ttcatgatgt atttttgtga tgtacatttt
     4141 ctcaacataa gggaaaaaca aattataaat ctgttctcct ccgaaaataa aaatttcttc
     4201 ttcgttttta cataactcaa aaacatcttc tattgaatga acaatttcac aaccattaaa
     4261 ggtaaacccc ttatctctcg tcagaataat atttcttctg tcaggtaagg ctcttccgat
     4321 tgattcaagg ttcttcctac ctaatattat cggatgtccc tttgtagtat ttttaacata
     4381 ttcccagtcc ttgggaatcc tccaaggaat gtcattctct ttgccaatca ctctattctt
     4441 atccatcgca gcaatcaaag aaactttcat ttataacaca gcctttttaa ctaatttacc
     4501 atctaatttc ttatttctat caaaaaacct tttctcatta tcctgcccgt tagttgaata
     4561 agcaattttt tctataagtt atattatcat aataccacaa aatcacaaat tttcattcaa
     4621 ttatcatttt caattgcatt ttataaatca ttttgtatgt aatttggtat gtaagttaaa
     4681 atgaaaaaag tagtccattt tgaagtacat tttgtcattt tgtactccaa aactgaacta
     4741 cttagtatag attactgttg cttctttact aatttaggtt tacttgttaa gaaagattat
     4801 ttacgcaaat gttcttcaac aatttgctga gatttatcag ctgtatcttc cacttcatct
     4861 tttgcttttt ctaacttttg aatatattgt ttccagcttg agttttcagc agttgcttcg
     4921 tctaatttct tttgtgtatc tgttaactga gtttctacat ttgttttttc ttgtgtcagt
     4981 gttgcgattt gttgattcaa accatttaca gtattttgta attctgaaag ttttgcttgt
     5041 gcttcttgta gtcttgctgt ccaatctgca ttcagatgat tgatttcatc atttttttgg
     5101 ttgatctcat ctagtttgac attgatttca ttttgtttgc tttgtagttg tgcatccttg
     5161 ctgactaatt gactttctaa gttttgtttt tctgctgccg attgattttt ttggttttct
     5221 aattcattta cttttgtttg gtattcttgg acatctgcct ttgaatcttg caatgtctgt
     5281 tctttttgtg ctagtcgagc ggtaagatct gtaatcgctt gctctttatc tgtcaatgta
     5341 tgatcaagct gtgtcagatt ctcattgatt gtatcaatat ctgtctctcc accccacaaa
     5401 ataatttcat ttgcgtaccg cgtgcctgtg tagccaatta gacatagaaa tgcaacgaca
     5461 atcccaccag taataaattt ctttttcatt tgcatagctc cttaatccaa tacttttaca
     5521 tgctaaaagt aagtgatctc aaacacaatg tcaagcgttt ttaaattaca tatgtaattt
     5581 t
//
LOCUS       DAFLVO010000122         5446 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.125, whole genome shotgun sequence.
ACCESSION   DAFLVO010000122 DAFLVO010000000
VERSION     DAFLVO010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5446
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.125"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..481
                     /locus_tag="L1U99_002741"
     CDS             <1..481
                     /locus_tag="L1U99_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HBN1213245.1"
                     /translation="EKELLFFSEYIDNPLIQEYILGEEYTIDVCLNFDSTPVSIVPRK
                     RIATRGGEILKGQIIKDRELIETTKKMLEKLNAIGHITIQCIKNEKGIFYLEINARYG
                     GGAPISIKSGANSPEYIIKMIDSKKNLRYRENYLDKMIALRYDQAIYLDEKGNVYND"
     gene            453..1169
                     /locus_tag="L1U99_002742"
     CDS             453..1169
                     /locus_tag="L1U99_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBN1213246.1"
                     /translation="MKKEMYIMIKAVIFDLDDTLVSEYDYVKSGYKCVARRLAVQKIF
                     PATFDEIYRVLLDLFAEDSKNVFNRLYDYFEIPYSKKEIKELVNVYREHKPDINFLEN
                     ADTLLTELRSRGYKLGIITDGYAITQRNKLDALKVDYLVDYICITDELGRELWKPHPI
                     SYLLLLEKFNLKAQECIYIGDNELKDFITAKSIGMQTIKIERVNGIYRESSLKFKRFY
                     QADKKIRSLWEIKNFLGVIS"
     gene            1166..2284
                     /locus_tag="L1U99_002743"
     CDS             1166..2284
                     /locus_tag="L1U99_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBN1213247.1"
                     /translation="MKSKRILLASPHMSEEGYEKEYVKEAFDTNWVAPLGANVNGFEK
                     ELAEYVGASHAAALSSGTAAIHLALKAAGVGKDDIVICQSLTFSATANPILYQGAIPV
                     FVDSDYETWNMKPEHLRTALEKYPNTKAVLVVHLYGLSANLDEITKICKEYDVTLIED
                     AAESLGTTYKGKYTGTFGDYGIYSFNGNKIITTSGGGMLVSNDKEKVEKVRFWATQSR
                     EKARHYQHNEIGYNYRMSNIVAGIGRGQLKVLNERIEKKRYIHSFYKKELSKLSNIQF
                     MPENNWNEPNYWLSVITIKGINANHLIDELDKNNIEARPVWKPMHLQPVFKNYDYIGD
                     DVAETLFDLGVCLPSDTKMTDEDLKYVVSTIKRVINDA"
     gene            2274..2894
                     /locus_tag="L1U99_002744"
     CDS             2274..2894
                     /locus_tag="L1U99_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBN1213248.1"
                     /translation="MMRKKTFYQLFGKRILDILLSGIALIVLSPIILIVGFLVRIKLG
                     SPIIFKQERPGKSEKIFSMYKFRTMTDERDHNGEYLPDEIRLTKFGKMLRATSLDELP
                     ELWNILKGDMSIVGPRPLLVEYLPLYSEKQRKRHNVRPGLTGLAQVNGRNAISWEEKF
                     DLDVYYVDKISFFNDLIIIIQTCKKVIKKENINTINNNIPEKFKGS"
     gene            3021..4190
                     /locus_tag="L1U99_002745"
     CDS             3021..4190
                     /locus_tag="L1U99_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBN1213249.1"
                     /translation="MCRVLNILFQYEKIIKKYKEKRVMAKYYNKKILIMANNDDGLYR
                     FRGMLIKNLVDQGNEVIVSLPKGKNIPKLIELGCQIIETPIDRRGINPKTDFKLFFNY
                     CNILKKIKPDMVIAYTIKPNIYGGLACRLRKVSYALNITGLGTAFQKKGVLKSLIVFL
                     YRLAAKKSKVIFFENFENMKTFQTLQIAKQSKYKLLNGAGVDVEHFSYLEYPKDEQVH
                     FLFIGRIMKEKGVDELFEAMKNLYSEEKNCVLDVLGYFEEDYGIKIEKYEKEGWLKYH
                     GYQSDIRPFVERAHCFVLPSWHEGMANTNLESAASGRPIITSDIPGCKEAVIESKSGY
                     LCERKNSCSLYNSMNKFLKLSYEQRINMGKMGRNYMIKKFNKKKVVDETIKSLFS"
     gene            4197..4592
                     /locus_tag="L1U99_002746"
     CDS             4197..4592
                     /locus_tag="L1U99_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1213250.1"
                     /translation="MFCKVCDRKEGFCGFRIDIKELAKVSDIFLFTTLQEGMPRSMME
                     AMASGLPCIASKIRGNVDLLVEGKGGYLVPAKDAELVAECLRELINNKSLRKYMGNEN
                     LSRIKEFEVSIVKKRIKEIYEEVIGESVK"
     gene            4589..>5446
                     /locus_tag="L1U99_002747"
     CDS             4589..>5446
                     /locus_tag="L1U99_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBN1213251.1"
                     /translation="MKNPMFSIIVPIYCVEKYLKDCLDSIRNQTFKNFEAILVDDGSP
                     DECPEICDYYSQIDGRLKVIHKKNGGIIDARKTGVTSAMGEYIVFLDGDDWLANTYLE
                     KYAEVITKYNPDIICSGYFASRSNKIRKRELSCSFGYYDKDKIINLIYPKLIEDEHGE
                     YFRPQLWAKAFRTTLYKEQQQVSGQVSVGEDHACTKPCIYHANSIYMMEKCLYYYRIN
                     ENSITKKPQPYYWEGPKAIGEHFEKQIDMNKYDFQDQVYRNVTHNLFNVAVSQFNKQD
                     KYLNIKKDII"
BASE COUNT         2121 a          635 c         1038 g         1652 t
ORIGIN      
        1 tgaaaaagaa ttgttgtttt ttagtgaata tatagataat cctcttattc aagagtatat
       61 tttaggtgaa gaatatacta tagatgtttg cttaaacttt gattcgacac cagtaagtat
      121 tgttcctaga aaaagaatag caactagagg tggggaaata ctgaagggtc agattattaa
      181 agatagagaa ctaattgaga ctacgaaaaa gatgttggaa aaattaaatg caatcggaca
      241 tattactatt caatgtataa aaaacgaaaa gggaatattt tatttagaaa taaatgcaag
      301 atacggtgga ggagccccca ttagcattaa atcaggagct aattcccctg aatatattat
      361 aaagatgata gattcaaaaa aaaatttgag atacagagaa aattatttag ataaaatgat
      421 agcactgaga tatgatcaag cgatttattt agatgaaaaa ggaaatgtat ataatgatta
      481 aagcggtgat ctttgattta gatgacactc ttgtgtctga atatgattat gtaaaaagtg
      541 gatacaaatg tgtagctaga agattagcag tgcaaaaaat tttcccggct acttttgacg
      601 aaatatatag agtcctttta gatctttttg ctgaagatag taaaaatgta tttaatcgtc
      661 tatatgacta ttttgaaatt ccttatagta aaaaagaaat taaagaactg gtaaatgtat
      721 atcgagaaca caaaccagac ataaattttt tagaaaatgc agatacttta ttaacggaat
      781 taagaagtag aggatacaag ctggggatta ttacagatgg gtatgctata acccaacgaa
      841 acaaattgga tgctttgaaa gtagactatt tggtagatta tatttgtatt actgacgaat
      901 taggccgtga attgtggaaa ccacacccta tctcatatct tttattgtta gaaaagttta
      961 atttaaaggc acaagagtgt atatatattg gcgataatga gttgaaagat tttataactg
     1021 ccaaatcaat aggaatgcaa acaattaaaa tagaaagagt aaatggtatt tacagagaaa
     1081 gcagtttgaa gttcaaaaga ttttaccaag ctgataaaaa aatacgttcg ttatgggaga
     1141 taaaaaattt tttgggagtg atttcatgaa aagtaaaaga attctattag cttctccaca
     1201 tatgagtgaa gaaggatatg aaaaagagta tgtaaaagaa gcatttgata caaattgggt
     1261 tgctccttta ggtgcgaatg tgaatggatt tgagaaagaa ttagcagaat acgtgggagc
     1321 tagtcatgct gccgcattat cttctggaac agcagctata catttagctt tgaaagcggc
     1381 tggggtcggt aaagatgaca tagtgatttg tcagtccttg acgttctcag ctactgctaa
     1441 tccaattctc tatcaaggag ctatacctgt atttgttgat agtgattacg aaacttggaa
     1501 tatgaaacct gaacatttgc gaacagcact agaaaaatat cctaacacaa aggctgtatt
     1561 agtagtacat ttgtacggtt tatcagctaa tttagacgaa attactaaaa tatgcaaaga
     1621 atacgatgtt actctaattg aagatgctgc agaatcatta ggaacaacat ataaaggaaa
     1681 atatactggt acatttggcg actatggaat ttattctttt aatggaaata agataatcac
     1741 aacttcaggt ggcggaatgc ttgtatccaa tgacaaagaa aaggtggaaa aagtgagatt
     1801 ttgggctacg caatctcgtg agaaggcacg ccattatcaa cacaatgaaa ttggctataa
     1861 ttatcgaatg agcaatatcg ttgctggtat cggtcgagga caattgaaag tattaaatga
     1921 aagaattgag aaaaaacgat atattcatag tttttataaa aaagaattgt ctaaattgtc
     1981 aaatatacaa ttcatgccag aaaataattg gaatgaaccg aattattggt taagtgtcat
     2041 aacaataaag ggaataaatg cgaatcatct tattgatgag ttagacaaaa ataatataga
     2101 agcccgccca gtatggaaac ctatgcattt acaacctgtt tttaaaaatt atgattatat
     2161 tggcgatgat gtagcagaaa ctttatttga cttaggagta tgtttaccat cagatacaaa
     2221 gatgacagat gaagatttaa aatatgtagt atctacgatt aaaagagtga tcaatgatgc
     2281 gtaaaaaaac tttctatcag ctttttggga aaagaatttt agatatccta ttgtcaggaa
     2341 ttgctctcat cgttttatcg ccgataatct taattgtagg ttttttagta agaattaaac
     2401 ttggttctcc aattatcttc aaacaagaac gaccaggaaa aagtgaaaaa attttttcca
     2461 tgtataaatt tcgtacaatg actgacgaaa gagaccacaa tggagaatat ttacctgatg
     2521 aaattcgact aactaaattt gggaaaatgc ttagagcaac aagtctggat gagctacccg
     2581 aactttggaa tattttgaaa ggtgatatgt cgatcgtagg acctcgtcca ttattagtgg
     2641 agtatttgcc actatatagt gagaagcaac ggaaaagaca caacgtaaga ccaggattaa
     2701 ctggactggc tcaggtcaat ggaagaaatg ctattagttg ggaagaaaag tttgatttag
     2761 atgtttatta tgttgataaa attagtttct ttaatgatct tattattata attcagacat
     2821 gtaaaaaagt aatcaagaaa gagaatatta atacaatcaa taacaatatc ccagaaaaat
     2881 ttaaagggag ttaaatacag cagcttaatg caagttttgt gacttgcatt atatttaggt
     2941 ataaatcaaa gcgagtatat tagaattata taacatatgt taaaaaaacg tatagctaat
     3001 aaaagtatga ttttaaaaat ttgtgtagag ttttaaatat actgtttcaa tacgagaaaa
     3061 ttataaaaaa gtataaggaa aagagagtta tggcaaagta ttataataaa aaaattctta
     3121 taatggcaaa caacgatgat ggtctttacc gttttcgagg aatgctcata aaaaacttag
     3181 tagatcaagg taatgaagtt attgtatctc ttccaaaggg caagaatatt cctaaattaa
     3241 ttgaacttgg atgtcaaatt attgaaactc caatagatag aagaggaatt aatccaaaaa
     3301 ctgactttaa actatttttt aactattgta atattttgaa aaaaataaag ccagatatgg
     3361 tcattgctta tactatcaaa ccaaatatat acggtggatt ggcatgtcgg ttaagaaagg
     3421 tttcttatgc attaaatata accggattag gaacggcatt tcaaaaaaag ggggttttga
     3481 aaagtcttat tgtatttttg tatagattag cagctaaaaa atctaaggtc atatttttcg
     3541 aaaattttga aaatatgaaa acatttcaga ctttacaaat tgctaaacaa agtaaataca
     3601 agctattaaa cggtgcagga gtagatgtag aacactttag ttatttagaa tatcctaaag
     3661 atgagcaagt tcatttttta tttattggaa gaattatgaa agagaaaggt gtagatgaac
     3721 tttttgaagc aatgaaaaac ttatatagtg aagagaaaaa ttgtgtactt gatgtccttg
     3781 ggtattttga agaagattac ggcataaaaa ttgaaaaata cgaaaaagag ggatggttaa
     3841 aatatcatgg atatcaatct gatattcgtc cctttgtaga aagagcacat tgctttgttt
     3901 tgcctagttg gcacgaagga atggcaaata ctaaccttga atcagcagca tcagggagac
     3961 caattattac aagtgatatc ccagggtgta aagaagcagt tattgaatcg aagtctggtt
     4021 atttatgtga aagaaaaaat agttgtagtc tctataattc gatgaataaa tttctaaaat
     4081 tatcatatga gcagcgcatt aacatgggaa aaatggggag aaattatatg attaaaaaat
     4141 ttaataagaa gaaagttgtc gatgaaacaa ttaaatcatt atttagttaa aaagatatgt
     4201 tttgcaaagt atgtgataga aaagagggat tctgtggctt cagaatagat atcaaagaat
     4261 tggcaaaagt ttctgatatt tttttattta ctacattaca agaaggaatg ccaagatcta
     4321 tgatggaagc tatggcaagt ggattgccat gtatagcaag taaaatccga ggtaatgtag
     4381 accttttagt ggaaggaaaa ggtggatatc ttgttccagc taaagatgca gaattagtag
     4441 cagagtgttt gagagaacta atcaataata aatctcttag aaagtatatg ggaaatgaga
     4501 acctttccag aattaaagaa ttcgaggtta gtatcgtaaa aaaaagaatc aaagaaatat
     4561 atgaagaagt tataggtgag agtgtaaaat gaaaaatcca atgttttcaa taatagtacc
     4621 tatctattgc gttgaaaaat atttgaaaga ttgcttagat tcaataagaa atcagacatt
     4681 taaaaatttt gaagcaatac tagttgatga cggtagtcct gacgaatgcc cagaaatatg
     4741 tgactattat tcccaaatag atggacgttt aaaagtaatt cataagaaaa acggtggaat
     4801 aatagatgca cggaaaacag gagtcactag tgctatggga gagtatatag tttttctaga
     4861 tggtgatgat tggcttgcaa atacttattt agaaaaatat gcggaagtaa ttactaagta
     4921 caatccagat ataatatgta gtgggtattt tgcatcacgt tccaacaaaa ttagaaaaag
     4981 agaattgtct tgctcgtttg gatattatga caaagataaa attataaatt tgatttatcc
     5041 taaattaatt gaggatgaac atggagagta ttttagacca caattatggg caaaagcttt
     5101 tagaactact ctgtacaagg aacaacaaca agtatctggg caagttagtg ttggtgaaga
     5161 tcatgcatgt acaaaaccat gtatttacca tgcaaattcg atatatatga tggaaaaatg
     5221 tttatattat tacagaataa acgaaaattc tataacaaaa aaaccacaac catattattg
     5281 ggaaggacca aaggctattg gagagcattt tgaaaagcag attgatatga ataagtatga
     5341 ttttcaagat caagtatata gaaatgttac acacaattta tttaatgttg ctgtttcaca
     5401 atttaataaa caggacaaat atttaaatat aaaaaaagat attata
//
LOCUS       DAFLVO010000123         5366 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.126, whole genome shotgun sequence.
ACCESSION   DAFLVO010000123 DAFLVO010000000
VERSION     DAFLVO010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5366
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.126"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            27..896
                     /locus_tag="L1U99_002748"
     CDS             27..896
                     /locus_tag="L1U99_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBN1213252.1"
                     /translation="MKKKKFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     VGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGDVEALITYDAVNSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVEAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            916..1263
                     /locus_tag="L1U99_002749"
     CDS             916..1263
                     /locus_tag="L1U99_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213253.1"
                     /translation="METISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGAMIIEREMLDEIRVIIPKDTQMCE
                     DSISDDEPKSERK"
     gene            1276..2538
                     /locus_tag="L1U99_002750"
     CDS             1276..2538
                     /locus_tag="L1U99_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213254.1"
                     /translation="MSEKSIELKEYKRSDGEKYYPVASFSKSVYLVGRALVVGAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNVQS
                     FFAKLHLVDISILVLEAGTVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRNKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATSGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETERATSSIAVSNSQFSFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            2618..3994
                     /locus_tag="L1U99_002751"
     CDS             2618..3994
                     /locus_tag="L1U99_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HBN1213255.1"
                     /translation="MAMKLLEKVKKRAEKAESILLDKEPNIKLNGKFSVNMLNTKAKD
                     PTDAIFGIKPDGTIAHFCISEMPHMLVAGTTGSGKSVLLNEILVTVMCHSTPDELKIG
                     IVDPKRVEFGRYKKLPFMLADPITDMDEAYDFFEYLVILMHERYKLMEKAGLQNITLY
                     NEYAEKNGLDRFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMLIKLVDGSMVRAQG
                     AYISNKEIETIFNHLRNTMPEPEYVDYRAIVAETRGEGGEDEDFGGIGKAPVRKSAKR
                     NLNTPLANPSSKEPSIEKKSAFAIKLEKNKEEKVEQGAKTLEKLQAEKLEKVLRALGK
                     ADPEPQTSNNTNNKQPIASKTKPKANDPKGSENVVITTDKSEKKQINGSTSPIMQKML
                     KAKKQVHK"
     gene            3991..4620
                     /locus_tag="L1U99_002752"
     CDS             3991..4620
                     /locus_tag="L1U99_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213256.1"
                     /translation="MIIVSSFLRWLTPYKYTDEVVVKRAKKRDKKAVLTPKQMLDHGI
                     LGVKVLEVNKPFESNSAREKLLGAEADVAYFYHDKSKHQIAIKFNPKSAWRYQARDDL
                     KRRKLRPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSNQNRVQINKFEKKVRK
                     FNDRKTILWFADICKQPDGTAKWEAVIFDENGKKVMSETWHDKAKFVWQ"
     gene            4639..5118
                     /locus_tag="L1U99_002753"
     CDS             4639..5118
                     /locus_tag="L1U99_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213257.1"
                     /translation="MLELFEANRTGFNQKLEVGETIEYKDKNYIIIGIYNTRINRIGD
                     PRITSDLVCQSVNYSPDLTSRYKKYVLLEYRHKITDEIGVNNTRNIFKIGTVIPYSNN
                     EEKIFYQIYGIEKFEYEHVDLLVTYQMRLIEPWSQAEIDKAVKLNRLSKFNVLGNAF"
BASE COUNT         2085 a          782 c         1092 g         1407 t
ORIGIN      
        1 gataacacaa taaaaggaat ggtggtatga aaaagaagaa gtttagccga tcgttgttag
       61 gaattttggt tttagttgcg gttggtctta gtggcaaggg ttactttcag aataacagta
      121 ctcaggaaca tgattttcag atcaaaagta gtgttcaggt aggtaataaa gcagacagtg
      181 aatcaaaaga atttttaggg atacgttatg atccaaacaa atatccaaat aatatcgtaa
      241 acattaatga tgggaaatat acactgacaa aagaagacca tgaagcatta tcagaaaaag
      301 gcagtcaaac cttttgggta aattatgcag atttagatca acttggaaga gcaggagatg
      361 ttgaagcgtt gatcacctat gatgctgtaa attctcactc atctaaaaat gtggaacgtc
      421 catctttcaa aagttctgtc catattgcag gagaatacaa ggatggagta tttgatcaag
      481 agagagatac ttgggtcggc aaagattcaa acaatgaaat cactcagcta gaaggctata
      541 aaggttatct ctataacaaa agtcattcat tagcatggtc gctaggagga gatatggagg
      601 tacacaattt aacacttgga acgagagcgc aaaatgttgg gaaaaatgat cagaatggag
      661 ggatggctta ctcagaaacg attgtacgtg atgcaatcta taaaaataag aatgaaaaag
      721 tattgtataa agttgatcca atttataaag ggaatgaatt agttcctcgt ggttctcatg
      781 tcgaagcttt ctcagttaac gataatggaa aaacggtaaa ccttaatgtt tatgtattta
      841 acaatcaaaa aggaatcaac atcaactatc aaaatggtac ttgggtaaga gattagaaat
      901 tgagaaggtg aagaattgga aacaataagc atcaatggat tagataaatc agttgcaaat
      961 cgaataaaaa aaggaaatgg ctactatctt ctgaagaagg gtaaatattc agttgctaga
     1021 gagttagaaa caatgagtat cgtgtatgta gctaagaatc attttgacgt agaacaggct
     1081 atttttgatc cagattctga aatagggaaa tgtgttgaat tatcagagaa aactgttagt
     1141 acaaaagggg cgatgatcat tgagagagaa atgttagacg aaatcagagt aatcattcct
     1201 aaagatacgc agatgtgtga ggacagcata agtgacgatg aaccaaaatc agaaagaaaa
     1261 taaggagata ttcagatgag cgaaaaatcc attgaattaa aggaatataa gcgaagcgat
     1321 ggagaaaaat attatcctgt agccagtttt tctaaatcag tatatctggt tggacgtgca
     1381 ttggtagttg gtgcaattgg catatatatt ttgcattggg taacaaaggt tgtacaactg
     1441 cttgtagata ccttagtaag tattcttgtc tcgttaaatg atgttaacgg aacagatgat
     1501 ttaggattaa aagagatgtt taaagagtta ctcaatgcgt tttttcccaa ttatttaagt
     1561 tattcatata atgtacaaag cttttttgca aagctacact tggtagacat ctctatttta
     1621 gtattagaag caggaacggt attctttgtt ggatatttgg ttactttgat gttcaggcat
     1681 cactatggag aacaaagacc attttttgat gatatggaaa gtagaaggtt gaaaagagaa
     1741 gctctagaag ctatggatgt gaagtatgat ccaaacaaga ttataggaga tgaaacgaac
     1801 aacaaaaaaa gaaaacgaaa caaaacgcaa ttagaatccg atgtgctatc aacgcttaaa
     1861 aatatcaaaa tttctgttca tacaagacgt gatctaagtg tcaatgaaga tattcgagaa
     1921 tatatcgtaa aaatcccgca accaaaaggg aagaaagtta gagaaacagt tttacgacaa
     1981 attcaagatt tagggtcgat cctgacaaga gcaacaagcg gacgagccaa atttggtgaa
     2041 aaagaagatg aagtttcagg cgattatttc attttccgag catcagtaaa tattgaaaga
     2101 gaacgtaagg aaagagtaag taccaaaaac aaagaaacgg aaagagcaac atcttcaatc
     2161 gcagtttcaa attcacaatt ttcttttcca atcaatctct ttgccgataa ttccaaaaat
     2221 atccaaaacc aaaccgaaaa agctagaaaa tatgccgaaa ctcaaaagca atctttagaa
     2281 ctttatctat cttctgctga cgtacctgca agtctaacag atatgcacgt tgggaataca
     2341 tctattgaat atttgtttac tttatctcgt accagaaaaa ttcaactaag ctcaatgaaa
     2401 gaagaaattg aaacttactt gcatatatca ggtgtaatcg tgcggatcaa cgcagggcgt
     2461 attcaaatta ctttaccatt aggagaaaat gatcgtattc caattgatgt accatcaatg
     2521 atcaatagcg tgttttagaa gacatcacaa atagaaacag aaaatacaaa ctaccagttc
     2581 acaaacagaa aagtaccgag aaaagtgagg aatagaaatg gctatgaaat tattagagaa
     2641 agtcaaaaag agagccgaaa aagctgaatc tattttgcta gataaagaac ctaatataaa
     2701 gcttaatgga aaattcagtg tcaatatgtt gaacacaaag gctaaagacc caacagatgc
     2761 tatttttgga attaagcctg atggcacaat tgctcatttt tgcatcagcg aaatgccaca
     2821 catgttggtt gcaggaacga caggatcagg gaaatcagta ttactgaatg aaattcttgt
     2881 tacagtaatg tgtcactcaa cgcctgatga attaaaaata ggaattgtag acccaaaaag
     2941 ggttgaattt ggaagataca aaaaattgcc gttcatgttg gctgatccaa ttacagatat
     3001 ggatgaagct tatgattttt ttgaatatct tgtgatcttg atgcatgaac gttacaaact
     3061 gatggaaaaa gcagggttac aaaacatcac gctatataac gaatatgccg aaaaaaatgg
     3121 attagataga tttccctatg tgatcttatt agttgatgaa tattcacagt tggttggaac
     3181 acataaagaa gtagaaggtt tgattgttca attaggacaa atggcaaggg cagcaggtat
     3241 tcatgttatc ttagcaacac aatctcctcg atcaacagtt gtcactggta ttatcaaagc
     3301 caattttccg tcacgtgttt gccttatggt agcaagtgat ttagaaagta ggattgtatt
     3361 agatgaaggc ggtggagaaa gtctaagtcc aaagggagat atgcttatta agcttgttga
     3421 tggaagtatg gttagagcgc agggagctta catcagtaac aaagaaattg aaacaatctt
     3481 caatcacctt agaaatacta tgccagaacc agaatatgtt gattaccgag caatcgtagc
     3541 tgaaactcgt ggtgagggcg gtgaagacga ggattttggt ggaattggta aagctcctgt
     3601 aagaaaatct gctaaaagaa atttgaacac acctttagca aatccatcat ctaaagagcc
     3661 atcaattgaa aagaagagtg cgtttgctat taagcttgaa aagaacaaag aagaaaaagt
     3721 cgagcaggga gctaaaacac tagaaaaact gcaagcagaa aaactagaaa aagttttaag
     3781 ggcattagga aaagctgatc ctgaaccgca aacctcaaac aacacgaata ataaacagcc
     3841 gattgcatct aaaaccaaac ctaaagctaa tgatccaaaa ggctcagaaa acgtagtgat
     3901 cacaactgat aaatctgaaa agaaacaaat aaatggaagt acttcaccta tcatgcaaaa
     3961 aatgttaaaa gcaaaaaaac aggtgcataa atgatcatcg tcagttcttt tttaagatgg
     4021 cttactccat ataaatatac agatgaagta gttgtgaaac gagcgaagaa aagagataaa
     4081 aaagcggtac taactcctaa acagatgctt gatcatggca ttttaggggt gaaggtttta
     4141 gaagtgaata aaccgtttga atcaaatagt gcaagagaaa agttgcttgg agctgaagcc
     4201 gatgtcgcat atttttacca tgacaaaagc aagcatcaaa tagctattaa attcaatcca
     4261 aaatcggcat ggcggtatca agcaagagat gacttgaaac gtaggaaact tagaccaatg
     4321 ctctatccag aaggaaaaga agcatttgat agaacccaca tcgttcccat tggttttcat
     4381 ggtacagaat cagataaccg cctattagta ggttggaaca gcaatcaaaa tagagttcag
     4441 atcaataaat ttgagaagaa agtaaggaaa ttcaacgatc gaaaaacgat cctatggttt
     4501 gcagatattt gtaaacagcc ggatggaaca gcaaagtggg aagcggtgat atttgacgaa
     4561 aatggtaaaa aagtaatgtc tgaaacatgg catgataaag ctaaatttgt ttggcagtag
     4621 cagtagaggt gaaaaagatt gctagaactt tttgaagcaa atagaacagg ctttaatcaa
     4681 aagttagaag tgggagaaac tatagaatat aaagataaaa actatattat tatcggaatc
     4741 tataacacga gaattaacag aataggtgat ccacgtataa ccagtgactt ggtttgtcaa
     4801 tctgttaact attcacctga tctgacaagc aggtataaga aatacgtgtt attagaatat
     4861 agacacaaga ttactgatga aattggtgta aacaacacac gaaacatatt taagatcgga
     4921 acagtgattc cttatagtaa caacgaagaa aaaatatttt atcagattta cggaatagaa
     4981 aagtttgaat atgaacatgt cgatctgcta gtgacgtacc aaatgcgttt aatagaacct
     5041 tggtcacagg cagaaattga taaagcagta aaattgaacc gattatcaaa atttaacgta
     5101 ttaggaaatg ccttttaaaa atcgcaatac acaaacagaa aaataccaaa aaattagcaa
     5161 tgaacgtagg taagaacatg acaataaata ataataaccc taaaaaatat aatgctcttg
     5221 tccaatgcta tatcgaaaac aaaattacaa tgcaagaagt cgctgatgaa ttaggcaaat
     5281 caaagagcct agtatcacac gattttaagc acaatgtttt tccgaacccg attgagctga
     5341 ggaaaaaatt tcaaaagaga gtttat
//
LOCUS       DAFLVO010000124         5363 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.127, whole genome shotgun sequence.
ACCESSION   DAFLVO010000124 DAFLVO010000000
VERSION     DAFLVO010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5363
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.127"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..191)
                     /locus_tag="L1U99_002754"
     CDS             complement(<1..191)
                     /locus_tag="L1U99_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213258.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGC"
     gene            complement(201..1016)
                     /locus_tag="L1U99_002755"
     CDS             complement(201..1016)
                     /locus_tag="L1U99_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1213259.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(1278..1721)
                     /locus_tag="L1U99_002756"
     CDS             complement(1278..1721)
                     /locus_tag="L1U99_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HBN1213260.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(1855..2193)
                     /locus_tag="L1U99_002757"
     CDS             complement(1855..2193)
                     /locus_tag="L1U99_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1213261.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(2181..2558)
                     /locus_tag="L1U99_002758"
     CDS             complement(2181..2558)
                     /locus_tag="L1U99_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBN1213262.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2782..3975
                     /locus_tag="L1U99_002759"
     CDS             2782..3975
                     /locus_tag="L1U99_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1213263.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(4141..4563)
                     /locus_tag="L1U99_002760"
     CDS             complement(4141..4563)
                     /locus_tag="L1U99_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1213264.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            4958..5152
                     /locus_tag="L1U99_002761"
     CDS             4958..5152
                     /locus_tag="L1U99_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213265.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            5149..>5363
                     /locus_tag="L1U99_002762"
     CDS             5149..>5363
                     /locus_tag="L1U99_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213266.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQA"
BASE COUNT         1645 a         1011 c          943 g         1764 t
ORIGIN      
        1 atgcaacctg gaccaataaa aagtaaagaa aaaataaagg aaaagacatt ccttccatct
       61 atcgacaaaa ggaacgcagc tgctatatac aagatattga cacaccaaaa acaaaggcta
      121 cttgccaatg attgatacaa ccaataaaag aattccatat aaacattttt gtcaaaacgc
      181 tgctctttca taatcacctc ctattccttc attcctgatg aagcgatccc ttctacaaaa
      241 tatttttgca tcgctaaaaa tataaaagca acaggaagaa cagaaacaac tgaggcagcc
      301 atgattaatg cgtactctgc atcaaatagc ccaataaaca ttttcaaccc taactggatt
      361 gttttatttt ccgtagaaga caaataaatg aatggcccca tataatcgtt ccatgtatta
      421 acgaatgtga tgatcgtcaa actggcaatc gccggttttg taagaggtaa aatgatcttg
      481 cgatagattc cccactctga taagccatcg atccgcgcac tctcacataa agaatctggg
      541 atactactgt agtattgctt caacaagaac acaccaaaag cattgaacgc ttgtaatagc
      601 accaacgacc acaacgtata tgttaaaccc acttttctca tcataatgaa ctgcgggatc
      661 atataagact gccaagggac agcaatcgtg ccgatatatg ctaaaaataa aatatcgcgc
      721 cctttaaaat ttagtttaga aaacccgtaa gcagcaaaac tagaagtaaa caactgaatc
      781 aacgtgatca caacgcttaa aaaagctgta ttcttaaaaa atgtcactaa aggaatacga
      841 gaccaaataa ccagataatt ctctaaatgc caagttttag ggatccattg aatcggaatc
      901 gtgaacactt cattatttgc tttgaatgaa gcagaaacca tccataaaaa aggaatgatc
      961 gtcaataaag ctaatacaat cagcagaatc atacccaacc attgaataaa gggcatgttt
     1021 tttgaacgaa tttttgcttt ttttctttca tttcgaacac ctccaaagtt ataatcttca
     1081 tttctttgta atgattacaa tccagaacaa cggttattat agctgattca tttccgttct
     1141 tcttatgttt gtaagcgctt atttaacaag ttatgtaaat ctctttattt tttttgattt
     1201 aaaaatgaaa aaatacaaaa gcaagactgt catacgtctc gcttttgtat tgaaatttct
     1261 tcgattagag atacttatta ctgttcaaaa gcttctttga aacggtgaat caattcattg
     1321 actacaggtg ataaaatccg attctttttc cagactagca tgcagttcgt ttcaatcatt
     1381 gggtcaagcg gaacgaatgt cactcgcttt gaaagatgac ttacagcacc ttctatgact
     1441 aaagcagcac ctacctgatt ctcaattagc gcaaatacat tgaaaatcaa attgtacgtt
     1501 cctgtgatca gcaactgctc cttttttatg cctaaccagt cagcaaacat tcgctgtatt
     1561 tctggacgct ttgagatcaa aagaggtaca ttcgcaaagt cttcttttgt tatcacgtct
     1621 ttttttgcta aaacagaatt ttctaaaatg agcaatcccc atttttcctt tcttggtaac
     1681 aaaatcgttt cgtatttctc tgtatctact ggatctagca aaatcgctaa atctaacagg
     1741 cttttttcta gtcactccgt gatatcatca cttgttccgc tgtggatatg aaattgaacg
     1801 ctgggataat cacggatcaa cttttctagt aatagtgcca atgtattcga attatcagct
     1861 tccacacagc cgatcgtaaa tcggccgctg aataattgtt tttttctgtt ctcgaattct
     1921 tgagtggttt gattcgttaa atctaaaatt tcttctgctc ggctttttta gaaaataacc
     1981 tgcttctgtc aagatcattt tgcggttttc gcgtacaaac agttctgttc ctagttcctc
     2041 ttctaactcc ttcagttgtc ggcttaaggt tggttgtgta agatgtagaa cttctgcggc
     2101 ttgagagatt gttccttctt ctgcaattgt ccaaaaatat tttagtaagc gtaactccat
     2161 agcgatgctc cttgattttt ttacttgata cattccattt tatttctaga taacacacga
     2221 tcatatttct tgatttttcc ttgtaaacgt tccaaacact cttgcatttc agcaatttct
     2281 ttcgtcaaaa gttcactttc ttcaatcaaa agcttacgcc gctcaaatac agttgcttct
     2341 ccttcgctag ataggcgaat atattcaatc aaagactcga tcgataatcc ggcatttcgc
     2401 atacagatcg taaagtcgac ccattttagg tcttcttctg tataatcacg gattccgcct
     2461 tttgtccgat taactggtgg aatcaacccg attcgttcat aatagcgcaa tgtatcggcc
     2521 gaaatgccct tttcttcact gacttgtttg atattcatct gatcactctt tctcttaatt
     2581 tcttgccact ttacttatgt attttattta ttctacaact ttaagtgtac tccaagtcaa
     2641 tactcatttc tattaaaact aagctggatt atctatatcg gttgtttgtg tattatttca
     2701 aataaaaaag tcttgttttt ttattctttt ttggatatac ttttaacaat ttagggaaat
     2761 tttaggaaaa ggggtataaa aatgacaacg tatcagcgaa aggtattatt atcgacatcg
     2821 gcgggaattg ctttagagaa tatggatatt atgtttttag ctttttcatt atcttcaatg
     2881 attacttctt ttcatattag tggtacgcaa gcgggtttca tttcaacgat cactaatttg
     2941 gggatgctca ttggaggtat tttttttggc atcatagctg ataaatatgg acgtgtgaaa
     3001 gtattttctc aaacggtcct tctgttttcg attgcttctt tattgatgta ttttgcttca
     3061 aacatctact tggtttatct ctttcgcttt atcgcaggtg taggagcggg aggagaatac
     3121 ggggcgtgta tgtccttgat ttccgaaagt ttttcaaaaa aacaaattgg acgagcttct
     3181 tcggttgctg gtattggtgc gcaggtcggt gcggctttgg ctgcgatttt agctgctgtg
     3241 atcattccaa cgtttggttg gaagatgttg tatgtcgtag gtgtactgcc ggtgttgatg
     3301 gtcttgttca ttcgtcgcgg cttgactgaa ccaaaggaat tcaaatctgt acaatctgcc
     3361 gaaaagaaaa ccaaacttag cagactgttt gaatcaaaac atcttgcttg gcaaacatgt
     3421 ggccttagta tcatggtaac tgtccaaatt gccggctatt ttgggttaat gaattggctg
     3481 ccttcaatta tgcaaaatcg attagggctt tcggtttctg ggtcttcatt gtggatggtc
     3541 agtactattt taggcatgtc tttggggatg atgacttttg gcataatcat ggataaattg
     3601 gggcctaaac tagccttttc tttgttttta atttgttcat ccttatctgt ctatctactt
     3661 gtgttagccc atagccagtg gagtttggta gcagccgctg tgatagtcgg ctactttatc
     3721 aatggcatgt atggtggata tggcgcagtg attagtagtt tgtatccaac agaaatccgc
     3781 gcgacggcga ataatttcat tatgaacctt ggacgagctg ttggtggttt ttcttctatc
     3841 gtcatcggtt tcttgatgga tcattatagt ttaactgccg taatcttgtt tttgagcggt
     3901 atttacctag tcagtctgct ggtcttgaca actcttactg gtgttacagc attaagggaa
     3961 agcttgcagc attgatagtt gagtctgtaa atgacaagaa agaggtgtgg caaaagcttg
     4021 catctgcggt aataagacca gccaaatcaa aaacatgaga cactgtttcc gtttggctgg
     4081 tcgtattact tgatgcaggg cagctttttc aactgctaat ttccttctat ctggcggcga
     4141 ctattctttg acgtccgtca tttcaaagta ctttactaat aacttagcat aacgaaaaac
     4201 tgtggataca ctcgtatatt gagcgtctgc ataatcttcc aaatttttct caggatgttg
     4261 atacatgaat tcaatcaaat gataattata tgattttctg tagaaatgaa gataaataat
     4321 gtagattggg aagttctcct gcttttccat agaaaagcgc cgattattct cattcttcaa
     4381 aatgacctta tcaggatatt tttggaacaa ttcttctaaa tctgttagat aattcaagat
     4441 agacttactt gataccttca attcgttttg tagttcttct attgaacacc aacgttctgt
     4501 ttcaagcagt aaatgaatca ttttaatttt cttttgagaa acttttgtta aaaaagtctg
     4561 catattttct cctcctgtat ctactttact atactacata caagaaaaaa aacggataca
     4621 aatatcatat tgtcacaccg tcaatagtgc ataaacctgt tattatttct ctttttttcc
     4681 taagtattct attgatatga atcatttaat cgtttattat ataaatgtca ataatctaat
     4741 aataaaataa cgtacatatt ttattattgc atacttaata acagaactat agcaaaaaat
     4801 cccgtgtatc aacacgggat tagattaagt ttcctcaatc actattcata acacaattat
     4861 tataacaagt aagtaaacaa ttgaaaagga catttattga aaacggttgt tttttactta
     4921 aggaggaaat ttagcgaaaa aattagttgc attgtttttg gtcgcaggaa gtttgttgag
     4981 tgggtgtggt gctactacgt ctactactca aagcacaagt tcagatcagg cttccagcag
     5041 cagtaccacg atctccgaaa gtacggcaga ttcatcgaaa gaacaagaac aaattgaaaa
     5101 gaaaaaagaa gagaaacaaa aagcggaaaa agctgcacta gaaaaaaagt gacagaagcg
     5161 gaatctgctt tgtcacaagc tgaagcaaat cctacaaaag aaaactatgc aactgcttca
     5221 gcagctatcc aagcgctacc tgaaaacaaa caagagttga caagccgtct tgctgcaatt
     5281 gattccacaa tcaaagcaaa agaagcagaa gaagaacgga aaaagcaaga agaaattgca
     5341 cgacaacaag cagaacaagc gca
//
LOCUS       DAFLVO010000125         5315 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.128, whole genome shotgun sequence.
ACCESSION   DAFLVO010000125 DAFLVO010000000
VERSION     DAFLVO010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5315
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.128"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            32..388
                     /locus_tag="L1U99_002763"
     CDS             32..388
                     /locus_tag="L1U99_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine-rich SFCGS family protein"
                     /protein_id="HBN1213267.1"
                     /translation="MIKVVIADRMGKGQNVAKGVEAAGGKAVVVPGMGADMRLGDVMQ
                     QEHADMGISFCGSGGAGALTAATKYGYPERHGMRSIEEGITAIKDGKTVLGFGFMDQE
                     ELGKRLTEEFIKKHGK"
     gene            404..754
                     /locus_tag="L1U99_002764"
     CDS             404..754
                     /locus_tag="L1U99_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4312 family protein"
                     /protein_id="HBN1213268.1"
                     /translation="MSVQKTIQQKVIVSGKGETKQHAFASALAEIQNKIMEQSNVLLR
                     IEPVNVDILKAVENKYTERFLFFFFPRQRISYEVELSVTVAVTEIKLADISFSQQMTE
                     DPNGIAIPFVTKKI"
     gene            783..1562
                     /locus_tag="L1U99_002765"
     CDS             783..1562
                     /locus_tag="L1U99_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4311 domain-containing protein"
                     /protein_id="HBN1213269.1"
                     /translation="MDFVIILVKSVIIGGLLGFAASVGAARMFHAPNTQGLGAFRTLG
                     EMNACMGDPASHFSFGLGFFFNAWASSVGAGAFTQDVTHRIIPNWAAAALLAKNKDVT
                     QTMHDPKKMGIIGAVIGAVVVAFLNTTAAAIPEALQVTAVSVLVPAATILINTVMPVI
                     FWLAALDAGKRTGFWGTLFGGIAQLIMGNAVPGVVLGILIGKGVDESGWNRVTKSMMI
                     AIVLLFIFSGFFRGFDMEMIKSFQLQVPNWLDNLHNIFSVK"
     gene            1573..2235
                     /locus_tag="L1U99_002766"
     CDS             1573..2235
                     /locus_tag="L1U99_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4310 family protein"
                     /protein_id="HBN1213270.1"
                     /translation="METTEEQAKVLEAKRQKSFWFADWSFPLIVGIMSAAVFAGTHMY
                     VMYGVGAFNEVSIVAMLKAGLDGGSYGAAAAFGASFLFARILEGSLVGILDLGGSILT
                     GIGIGVPAILLSMKIAAPIDNFALSLLTGLVLGLIVGGIIVLIRKFTINQSNSTFGAD
                     VMMGAGNSSGRFLGPLIILSACAASIPIGIGATLGALGFYAWKKPIAGGAILGAIFPA
                     VN"
     gene            2254..3360
                     /locus_tag="L1U99_002767"
     CDS             2254..3360
                     /locus_tag="L1U99_002767"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HBN1213271.1"
                     /translation="MFDTLIKNGRLVDGSKIEVAIEKGMIKAVAAEINQPAQEVVDLE
                     GKYYLSAGWIDDHVHCYEKMNLYYDYPDQIGVEKGVTTVIDAGTTGAENIREFYQLTK
                     SVKTNVYALMNISKWGIVKQDELADLTKIQEDLVSTALAELPEFIVGIKARMSKTVVG
                     ENGIKPLELAKKIQTENNDLPLMVHIGSAPPELEEVLSRMERGDVLTHCFNGKPNGIL
                     DPKTDQIKNFVWDAYNNGVVFDIGHGTDSFNFHVAETALKAGMKATSISTDIYIRNRT
                     NGPVFDLATTLEKLRVVGYSWEEIIEKVTAVPARNFHLKNKGQLAVNYDADLTIFEIV
                     ENEKELKDSNGFTRIAKEQILPIKTIIGGVIYDN"
     gene            3350..4441
                     /locus_tag="L1U99_002768"
     CDS             3350..4441
                     /locus_tag="L1U99_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HBN1213272.1"
                     /translation="MTISYGKFDLKEVINASGKMTILGVSKVSESVLAAQRFGGEHFF
                     EMSDLAIKTGAYLSQLLKVEDAQIVSSASAGIAQSVAALIGQGDMYHVYHPYTEKIAR
                     REIIIPKGHNVDYGTPVEVMVAQGGGKVIEAGYANMCTPEHVSMMITEKTAALLYIKS
                     HHAVQKSMLTVAEMVEVAKAHRLPLIVDAAAEEDLFKYSEMGVDLVIYSGAKAIEGPS
                     AGLVIGKKKYIQWIRLQSKGIGRAMKIGKDNILGFTQALEDYLKNGSESGDSMKQRLA
                     PFVNAINQLPDLSAKIVQDGAGRDIYRASVTINGDKSAKEVIQELKARNPAVYTREYQ
                     ANNGIIEFDIRSVSQNEMEKIIKRLREIM"
     gene            4454..5194
                     /locus_tag="L1U99_002769"
     CDS             4454..5194
                     /locus_tag="L1U99_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HBN1213273.1"
                     /translation="MSVIPNYYKNRVCLNVLAHSVENAKACYEAAEGHVVLGVLSKNY
                     ASDEAAIEDMKRYQDATNNALSVGLGAGDPNQSQMVSRLSGVLQPQHVNQVFTGVGTS
                     RALLGQNDTVINGLVSPTGKIGYVNIATGPLSSQAPAAEVPIETAIQMLQDMGGTSIK
                     YFPMKGLAHREEFKAVAEACAKYEFYLEPTGGIDLSNFEEILKIAIDAGVKKVIPHVY
                     SSIIDKETGDTRIGDVKILLSMVKKIIH"
BASE COUNT         1711 a          868 c         1265 g         1471 t
ORIGIN      
        1 acaaatgata ttttacgagg aggaaacaat catgattaaa gtagttattg cagaccgtat
       61 gggtaaagga caaaatgtgg ccaaaggggt agaagcagct ggtggaaaag cagttgtcgt
      121 accaggaatg ggggcagata tgcgtttggg cgatgtgatg caacaagagc atgcagatat
      181 gggtatctct ttttgtggta gtggtggtgc aggtgcatta acagcagcaa caaaatatgg
      241 ctatccagaa cgacatggta tgcgttcgat tgaagaaggg atcacagcta tcaaggatgg
      301 caaaactgtt ctaggtttcg gctttatgga tcaagaggaa ttagggaaac gtctgacaga
      361 agaatttatc aaaaagcatg gaaaatagaa agagggacat gaaatgagcg ttcaaaagac
      421 aattcagcaa aaagttatcg tctccggtaa aggggaaaca aagcaacatg cttttgcatc
      481 agcgttagca gaaattcaaa acaaaataat ggaacaatca aacgtattat tgcgaatcga
      541 accagtcaat gtggatattt taaaggcggt cgaaaacaaa tacacagaac gctttctatt
      601 tttcttcttc ccacggcaac gtattagcta tgaagtcgaa ctctctgtta ctgtggctgt
      661 aacagaaata aaattggcag acatatcgtt cagccagcaa atgactgaag atccaaatgg
      721 gattgccatt ccatttgtaa ctaaaaaaat ctaattttga atcataaggg ggaaagaata
      781 acgtggattt cgtaatcatt ctagtcaaat cggtcattat cgggggatta cttggttttg
      841 cagcatctgt cggggcagct cgaatgtttc atgcacctaa tacacaaggt ttaggagctt
      901 ttagaacatt aggcgaaatg aatgcctgca tgggtgatcc agcttctcat ttttcatttg
      961 gtttaggctt tttctttaat gcatgggctt cttcagttgg tgctggtgca ttcacacaag
     1021 atgtgacgca tcgaatcatt cccaattggg cagcggcagc acttctagca aaaaacaaag
     1081 atgtcaccca gaccatgcat gatccgaaaa aaatggggat cattggagcg gttatcgggg
     1141 cagtggtggt agccttctta aacacaacag ctgcagcaat tccagaggcg ttacaagtga
     1201 cggcggtttc cgttttggta ccagcagcga cgattctgat caatacagta atgccagtta
     1261 ttttttggtt ggcagcttta gacgcaggga aacgaactgg tttttggggc actctttttg
     1321 gtggtatcgc gcaattgatt atgggaaatg cggtacctgg tgttgttcta ggaatcttga
     1381 ttggtaaagg cgtcgatgag agcggttgga atcgcgtcac gaagagcatg atgatcgcta
     1441 ttgttttatt atttattttc agtggatttt tccgtggatt tgatatggaa atgatcaaga
     1501 gcttccagct tcaagtgcct aattggcttg ataacttgca caacatcttt agtgtgaaat
     1561 aggaggagaa tcatggagac aacagaagaa caagcaaaag tattagaagc aaagcggcaa
     1621 aagagctttt ggtttgcaga ctggtctttt ccgctaatcg taggaattat gtccgctgct
     1681 gtatttgcag gaacacacat gtatgtgatg tatggtgtgg gtgcattcaa tgaagtttcg
     1741 atcgtggcga tgttaaaagc cgggctggat ggcggatcct atggcgcagc ggcagcgttt
     1801 ggtgctagtt tcttatttgc cagaatttta gaaggctctt tagttgggat cttggactta
     1861 ggcggttcga tcctaactgg gatcggaatt ggggtaccag caattctctt aagtatgaaa
     1921 atagcggcac caatcgataa ttttgcactc tctttattga ctggtttggt tctaggtttg
     1981 attgttggtg gcatcattgt cttgattcgt aaatttacga tcaatcaatc aaattccact
     2041 tttggtgctg acgtcatgat gggggcagga aattcatctg gacgtttttt gggtccatta
     2101 attatattaa gcgcgtgtgc agcatctatt ccaatcggca ttggcgctac attaggagca
     2161 ctaggattct atgcttggaa aaaaccaatt gctggaggtg ctattttagg agcaatcttc
     2221 ccggcagtaa attaatagaa agagggtcat taaatgtttg atactttgat taaaaatgga
     2281 aggttagttg atggatctaa aatagaggtc gctatagaaa aaggcatgat taaagcagtt
     2341 gcagcagaaa taaatcagcc ggcgcaagaa gtagttgact tggagggaaa gtattattta
     2401 tccgctgggt ggatcgatga tcatgtccac tgctatgaaa agatgaatct ttattatgac
     2461 tatcctgatc agataggggt cgaaaaaggt gtgacgacgg tcattgatgc tggaactacg
     2521 ggagcagaaa acatccgtga attttatcaa ttgacgaaat cggtcaagac aaatgtgtat
     2581 gcgctaatga atatctctaa atggggcatt gtcaaacaag atgaacttgc tgatctaaca
     2641 aagattcaag aagatctagt aagtactgcg ttagcagaac tgccggaatt tattgtcggg
     2701 attaaagcga gaatgagtaa gacagttgtt ggtgaaaatg gcattaagcc attagaatta
     2761 gctaaaaaaa tccagacaga aaacaatgat ctgccattga tggttcatat cggttctgca
     2821 cctcctgagt tagaagaagt attgtcaaga atggaaagag gcgatgtatt gacccattgt
     2881 tttaatggaa aaccaaacgg tattttagat ccaaagacag atcaaattaa aaactttgtc
     2941 tgggatgctt acaataatgg tgtcgtcttt gatattggac atgggacgga tagctttaat
     3001 ttccatgtgg cagaaaccgc actaaaagca ggaatgaaag ctacctctat tagtacggat
     3061 atctacatcc gcaatcgtac aaatggccca gtttttgatc tagcaactac tttagaaaaa
     3121 ttgagggtag tcggctattc ttgggaagaa atcattgaaa aagttacagc agttcctgca
     3181 cggaattttc atttgaagaa taagggccag ttagctgtca attatgatgc agatttgacg
     3241 atatttgaga ttgttgaaaa tgaaaaggaa ttgaaagatt ccaacggatt tacacgtata
     3301 gctaaagaac aaattttacc gattaaaaca attattggag gcgtcatata tgacaattag
     3361 ctatggaaag tttgatttaa aagaagtcat taatgcatcg ggaaaaatga cgatcctagg
     3421 ggtttctaag gtatctgaaa gtgtcctagc agcacaacga tttggaggcg agcatttttt
     3481 tgagatgagt gatcttgcca tcaaaaccgg cgcttatctt tctcaattac tgaaagtgga
     3541 agatgcgcaa atcgtttctt ctgcttcagc agggattgct caatctgttg ctgctttaat
     3601 cggacagggc gacatgtacc atgtctatca tccctataca gaaaaaatcg ctagacggga
     3661 aatcatcata cctaagggac ataatgtaga ttatgggaca ccggttgaag taatggttgc
     3721 tcaaggtgga ggaaaagtca tagaagctgg ctatgcaaat atgtgtacac cggaacatgt
     3781 ttccatgatg attacggaaa aaactgctgc gcttctatat attaaaagtc atcatgcagt
     3841 tcagaaaagt atgctgacgg tggcagaaat ggtagaagtt gccaaagctc atcgtttgcc
     3901 attgatcgtt gatgcagctg cggaagaaga tttattcaaa tatagcgaaa tgggcgttga
     3961 cttagtgatt tactctgggg caaaagcaat cgaaggtccg agtgccggac tggtcatagg
     4021 aaaaaagaag tatattcaat ggattcggct acagtctaaa ggtattggcc gagcaatgaa
     4081 aatcggtaaa gataatattt taggctttac ccaggcacta gaagattatt taaaaaatgg
     4141 gagcgaatcc ggtgactcca tgaagcaacg attagcgcct tttgttaacg caatcaatca
     4201 acttcctgac ctttcagcga aaatagttca agatggtgcc ggcagagata tttatcgagc
     4261 aagtgtaacg attaatggcg ataaaagtgc gaaagaagtc attcaggaat taaaagcacg
     4321 aaatccagca gtctacaccc gagaatatca agcaaataac ggaatcattg agttcgacat
     4381 tcgttccgtc agccaaaacg aaatggaaaa aattataaaa agattgagag aaatcatgta
     4441 ggaggctttt aaattgtcag ttatcccaaa ttattataaa aatcgtgtat gtttaaatgt
     4501 attagctcat tcagttgaaa atgcaaaagc atgctatgaa gcagcggaag ggcatgtcgt
     4561 actaggtgtg ctatcgaaaa attatgctag cgatgaagca gcaatcgaag atatgaaaag
     4621 gtaccaagac gcaaccaata atgcgttgtc agttggatta ggcgctggag atccaaacca
     4681 aagtcagatg gtttcgcgtt tatctggggt tttacaacca caacatgtca atcaagtatt
     4741 tactggcgtg gggacttctc gtgctttatt gggccaaaat gatacagtca tcaatggatt
     4801 ggtttcacca acaggtaaga tcggctatgt caatattgct acaggtccgt taagttcaca
     4861 agcgccagca gctgaagtgc ctattgaaac tgccattcaa atgctgcaag acatgggagg
     4921 tacttcaatc aagtatttcc cgatgaaagg cttagcacat agggaagaat ttaaagcagt
     4981 tgcggaagct tgcgcaaaat atgaattcta tttagagcca acaggaggaa ttgatctttc
     5041 aaactttgaa gaaattctga aaattgcaat cgatgcaggt gtaaaaaaag tgattcctca
     5101 tgtttatagt tcaattatag ataaagaaac aggagatacg cgtataggag acgtaaagat
     5161 actattaagc atggtaaaaa aaattattca ctaactcatt agaaaataag aagcttattc
     5221 cagaatgaaa ttaaatggaa taagcttttt ataattaatt acggaaattg ttaatgtaga
     5281 taataattta gatgtacgta agcagaagta cagaa
//
LOCUS       DAFLVO010000126         5311 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.129, whole genome shotgun sequence.
ACCESSION   DAFLVO010000126 DAFLVO010000000
VERSION     DAFLVO010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.129"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="L1U99_002770"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="L1U99_002770"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBN1213274.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="L1U99_002771"
     CDS             complement(1297..2133)
                     /locus_tag="L1U99_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1213275.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..3534)
                     /locus_tag="L1U99_002772"
     CDS             complement(2317..3534)
                     /locus_tag="L1U99_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBN1213276.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3683..3862)
                     /locus_tag="L1U99_002773"
     CDS             complement(3683..3862)
                     /locus_tag="L1U99_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213277.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            3917..4000
                     /locus_tag="L1U99_002774"
     tRNA            3917..4000
                     /locus_tag="L1U99_002774"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3951..3953,aa:Leu,seq:gag)
     gene            complement(4240..4818)
                     /locus_tag="L1U99_002775"
     CDS             complement(4240..4818)
                     /locus_tag="L1U99_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213278.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
     gene            complement(4824..5207)
                     /locus_tag="L1U99_002776"
                     /pseudo
     CDS             complement(4824..5207)
                     /locus_tag="L1U99_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347134.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1653 a         1082 c          838 g         1738 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga
     2821 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
     2881 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
     2941 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
     3001 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
     3061 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
     3121 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
     3181 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
     3241 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
     3301 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
     3361 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
     3421 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
     3481 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
     3541 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
     3601 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
     3661 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
     3721 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
     3781 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     3841 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     3901 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     3961 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     4021 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     4081 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     4141 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     4201 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     4261 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     4321 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     4381 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     4441 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     4501 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     4561 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     4621 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     4681 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat
     4741 acgcacataa tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa
     4801 taaaaataag atattcatgt ctaaaaaaac ggctttccaa atgatgaaat acctaaatct
     4861 aacttattaa gaaagttgaa atttttatat tcaggaaacc atttattaat ttcatgtgca
     4921 gcacgtaatg cattccctgg agttgtcaaa gagaaaatta attctgctaa gcttattatt
     4981 gaaaatactg ataacttata attatatcgt ccattgacaa tcaaatataa actaactata
     5041 cttgttagaa caaaaaaaca ggcgttgact tgttcttgat tagttaaaaa tatcaataaa
     5101 ggaatactta cccaatatat ttttctattt atttcttctc ctcttaagag ttgaaaaaac
     5161 ggataaaaag ttagtaaact aaatgctact ggccactgat agttcaaggt ggttgctctc
     5221 caaccggttt cccccattac tgtcaatggt attaaacagt atatagagca aaccaataat
     5281 aaatttttaa catttatttt ctcaaaaaca t
//
LOCUS       DAFLVO010000127         5051 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.132, whole genome shotgun sequence.
ACCESSION   DAFLVO010000127 DAFLVO010000000
VERSION     DAFLVO010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5051
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.132"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(82..1890)
                     /gene="pepF"
                     /locus_tag="L1U99_002777"
     CDS             complement(82..1890)
                     /gene="pepF"
                     /locus_tag="L1U99_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBN1213279.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(2066..3064)
                     /locus_tag="L1U99_002778"
     CDS             complement(2066..3064)
                     /locus_tag="L1U99_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HBN1213280.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(3290..3943)
                     /locus_tag="L1U99_002779"
     CDS             complement(3290..3943)
                     /locus_tag="L1U99_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HBN1213281.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            complement(4275..4673)
                     /gene="spxA"
                     /locus_tag="L1U99_002780"
     CDS             complement(4275..4673)
                     /gene="spxA"
                     /locus_tag="L1U99_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBN1213282.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT         1498 a         1038 c          767 g         1748 t
ORIGIN      
        1 taaaaaaata cgtcgactcc cttacaagag agccgacgta tttttttcgt ttctattcga
       61 gaaaatcaaa aatagaaagc cttataaacg atcgatcaat tcttctaatt catttagacg
      121 ttgttcaaac atcgacattg catcttcaat atatgcagcc tgtgtcatat caactcctgc
      181 ttttttcatt acttccacag gataatcgct gttacctgct tttaggtaag ccaagtagtt
      241 ctctagtgcc tctggttcct ggtttagtat tttcttcgcc agtgctgaag cagcagaaaa
      301 gccagtcgag tattggaaaa catagtaatt ataataaaaa tgcggtatcc gtgaccattc
      361 gaatttaatt tctgggtctt cttcgactgc tggaccataa tattttgcat tcaatttacc
      421 ataactatca cttaggtatt cactagtcaa tggcacacct ttttcatctt ccgtatgcat
      481 gaaatgctcg aattcagcga attgtgtctg gcggaaaact gttcctttaa acccatccaa
      541 gtaatggttg agtacataag cccgtacacg agggtctttt tctgtttcca ataaatactc
      601 cgttaggata ttttcattcg ttgtcgaagc aatttctgct aaaaagatgg agtagtcgcc
      661 gtacacataa ggctggttcg aacgagtgaa ataactatga acactatgtc ccatttcgtg
      721 gacaagcgta aatagctgat ccagcgtatc atgccaattc aataaaatat atggatttgt
      781 gtcatagctt cccgaagaat aagcaccgct tcgtttccct ttattttcga caacatcgat
      841 ccaacgttca gagaatgctt tttctacgat ggccatgtat tcttcaccca ttggtttcag
      901 tgcttctaaa gctttttctt ttgcttcttc gtacgtaaag gtaattggag cttcccctaa
      961 gaccggtgta taaagatcat acatgtgcag tttttccact tctaataaac gtttccgtaa
     1021 ttccatgtat cgatgtaaca aaggcaaatg cttgtttacc acgtctacca aagtatcgta
     1081 tacactttca ggaatatgat tattgctcaa agacgcttct ctggcagagc tgtaattacg
     1141 gactttcgct ttaaaattat gtccttttat atgtgtgcct aaagtagaag caaatgtatt
     1201 tctaaattgt tcgtaaacac tgtacaaccc cttaaatgct gcttcgcgca cccttcgatc
     1261 cgtgctttct agcaactgac catacacgcc atgagataat tggactattt caccattttc
     1321 tccttcaatc gttggaaaaa ctagatctgc attattcaaa acagcaaatg tatcacttga
     1381 agcatcaaag atttcacctg ctccagcaag aagagattcc tgctcagcag ataagacatg
     1441 ggctcgatta tctactattt gctggatata atggcgatag acttccaatt ttggttcttc
     1501 tttgaaatat tgccaaatct ggtcatctga caattgcaat atttctggtt caaaccagga
     1561 aacggcttca ctaactttcg aaaacagact gcttgctctt gcataaagcg cttggtaatc
     1621 tgtatttcca gtgtcttgat cgtttttaag gtgcgcatat acataaatga cttcagtttg
     1681 gcgataaacc ctcaatacga attcaatcgc atttaaaaat tgagaagcgc cttgatcaag
     1741 tgttcctttg tgtttttcag attgttttaa ctcttctgat aattccaaat atttctcatc
     1801 aaactcttgg tcgcttgaaa agatcttggt caagtcccaa gttaaatttt caggcaattc
     1861 ttctcgtttt ggcaactgct ttacttccat gaaatccact ccttttcttc ccttagctct
     1921 atctatcaaa atagatcata gtctaacatc cacatgtcac agcatctaac ttttctactc
     1981 attcatgtgt ctgcttccat caattttagc ataactaaat cttgttttac atagaaaacc
     2041 gattcctagc ctatttttat acttactatt ttttcaaaga agacaagtgt atgcattcgt
     2101 taaaaaactg ctgatagacc atctcttcat caatcatagg aaaaagccat tcccttttat
     2161 gttcttttat ttggcaaagc catgagttga aatcaggaac tttctggttt tccaaggctt
     2221 cttcgtacaa cattcgataa agaaaaacct gttcttgtaa ataaaagaaa aaccgacttt
     2281 tttgatagat ccacgatgat agatgcaaaa gatgtttatg acgcaagtag cattgttctt
     2341 gtatggatac tgtattcttt tgcttgtgaa taagttggcg tgtcagccat ttcttcccat
     2401 cttcactcac tttttctatt tttttcattt ggttcatttt aatttcgtta ctagtgaata
     2461 tttctttaag gtccctacta gaaaaagtcc agcagctact gcaaaaggaa atatgccctg
     2521 atacagtctc tgtaatatga tgatacaaat aaagcttttg tttcttgaga tcagctttcc
     2581 agcaatgcac tcctcttttt ctattatagt agcagcaact tttttctatc aatgagaatt
     2641 gcgattgtcc aagaaaagaa ttaccaagta tccaccatac ttggtaactg ttattcaaat
     2701 aattttgggt tctttcaata aatctctggt gagacagtct agaacattgg atttctattg
     2761 ctagattcgc caacaaaata tccggccttt gccgcaacct cggcaaatag gcttccaaaa
     2821 atactggttc tactgactgt cccagccaat ccatgaagca ttcctttaac tgtaagtgct
     2881 cttttgattc tctttcacta aagaccgaac agttatctga tttttgatgg gcaaaatgag
     2941 cacatttttt ctttcccttt ttcaaaatca ctctttttcg acagccacga caataatatt
     3001 tctttccttt ttctgcatgt ttagcaaaac agcacttatt atattcattc attgcaagca
     3061 gcatttttct ccctctgaac ttatttacgt ctaagaattt atttacacga aaaaagaggg
     3121 cgtgaaaaag ctattctgca tcaagtaata agaacagcta aacaaaaata gttcccaata
     3181 tttttcgttt ggttgggctt gttaccgcag atgcaagctt ttgaacacat ttatacgaaa
     3241 aaaagactgc gacacaattt ttgtcacagt ctcttactat aatgctgatt tatacaaaat
     3301 aaaatttcgt tcgctcgata gcattacgcg ccatcagaca ttgtccatat tcattcaatg
     3361 tttctggtgt acgatcgctc ttttcagcaa actccaaaat tcgagcaatc tgattctcta
     3421 catccgcttg gttgagattt tccatccaga agtgaacgac taggtaatag cgctcttcga
     3481 ataaatacaa atcagtccaa gcagactcta gttcgacatc tgttgcaagt tggatcactt
     3541 gttcaaaatc ttcaaaagca aaagttgctt gtctttcctg ttcttctagg gcgcttccag
     3601 ataattcttc ctccggatcg ctgccaataa tctgctgacg aagaaagtca ctcacatctt
     3661 ctgaatcaac agtagaatct tctgattgag aaatttcttc atccggaaga tttttactga
     3721 taaacagttc taatccgtct ccttttggca aaacttggaa agtgacagct tcgcttcctc
     3781 ggaactcctc ttcgatatca acttcttcca aaatactata aaagaaattt tcgatttctt
     3841 tgtgattgcc aagtaaatcc aaaaatgaaa cgccccgttc ctctaaatct tcatgaccaa
     3901 ttagtacacg gatcgtattt tcattaatat gttccatttc cattttgcta cacctcactt
     3961 tgccacaatg tttaatatag attcattgta gcgaaatcag cttaaatgta aagaaaaaaa
     4021 atctcgctgt taagcgaatt taataaaacc agcggatttt tcaacctttc aagctatctt
     4081 atttaactat aacatttttg gcagacgaat actatatagc cgacttttca gctaattttc
     4141 cctctctatt tttcgtgcaa tcatcatctt ctactacctt tttatacatc taatcaagaa
     4201 tactttttgt aaaaacaaaa aaacttggaa aaactatctt tgtaatagtc ttttccaagt
     4261 ttcgtattat ccttctataa tccagccatc aattgtgctt gacgtaattc taattgtcgt
     4321 acatcgcgcg gtaggaaccg acgaatttca tcttcattaa aaccaacttg cagacgttta
     4381 tcatcaatca tgattggacg gcgaagcaat ccaggattgt tttgcacaag ttccaataat
     4441 tcttgtaacg gcagatcatc taaatccatg ttcagttttt ggaatacttt ggaacgtgtc
     4501 gagatgattt cttctgttcc gtcttctgtc atttgtaaaa tcgcttttaa ttcagaactg
     4561 ttcaatggtt ctgaaaaaat attacgttca acaaatggaa tctgatgttc ttgcaaccac
     4621 gcacgagcct ttctgcagga agtacaactt ggggaagtat ataatgttaa caacgtgcac
     4681 cactcctttt cgtgataaga atcacttttt tgtaacagaa gatcataata atctcccatc
     4741 tgtttctatt atacataatc aacttttaaa tagctacctt tttttcataa tttttttaaa
     4801 aaaatgaaag ttatctaagg ttaatataca gtaaaaccag cattctcgct ttttttatca
     4861 tttaaaaatt agagttttca aatctaattc aaattttcta aacatatgaa acagcgtata
     4921 aaactgtact attattttat ctcaaaagct aaatgaaacc gatttcttaa gattttttat
     4981 gttttttatt tctttaatag taatgttttc tgtcatttta aataatactg ttctttatta
     5041 taacgcttat t
//
LOCUS       DAFLVO010000128         5015 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.133, whole genome shotgun sequence.
ACCESSION   DAFLVO010000128 DAFLVO010000000
VERSION     DAFLVO010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5015
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.133"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..182)
                     /locus_tag="L1U99_002781"
     CDS             complement(<1..182)
                     /locus_tag="L1U99_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBN1213283.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
     gene            517..951
                     /locus_tag="L1U99_002782"
     CDS             517..951
                     /locus_tag="L1U99_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBN1213284.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            974..1294
                     /locus_tag="L1U99_002783"
     CDS             974..1294
                     /locus_tag="L1U99_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213285.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            1435..1626
                     /locus_tag="L1U99_002784"
     CDS             1435..1626
                     /locus_tag="L1U99_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213286.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(1697..1954)
                     /locus_tag="L1U99_002785"
     CDS             complement(1697..1954)
                     /locus_tag="L1U99_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBN1213287.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            2112..2375
                     /locus_tag="L1U99_002786"
     CDS             2112..2375
                     /locus_tag="L1U99_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213288.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            2399..2587
                     /locus_tag="L1U99_002787"
     CDS             2399..2587
                     /locus_tag="L1U99_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213289.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(2670..2855)
                     /locus_tag="L1U99_002788"
     CDS             complement(2670..2855)
                     /locus_tag="L1U99_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213290.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            3070..3441
                     /locus_tag="L1U99_002789"
     CDS             3070..3441
                     /locus_tag="L1U99_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBN1213291.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(3591..3663)
                     /locus_tag="L1U99_002790"
     tRNA            complement(3591..3663)
                     /locus_tag="L1U99_002790"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3628..3630),aa:Gln,seq:ctg)
     gene            complement(3709..4137)
                     /locus_tag="L1U99_002791"
     CDS             complement(3709..4137)
                     /locus_tag="L1U99_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213292.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(4197..4850)
                     /locus_tag="L1U99_002792"
     CDS             complement(4197..4850)
                     /locus_tag="L1U99_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBN1213293.1"
                     /translation="MNTAQKSSTQKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTS
                     LSMLLSFYGYETTKNQLAEQLDYVPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPV
                     ASLAQQIVQTDYHTFPKTDAQLDDIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNN
                     GEVRVTPLVHACVVTGYDKENIYVNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
BASE COUNT         1747 a          783 c          981 g         1504 t
ORIGIN      
        1 gaatttgatt ctgcaatggc attgatcaag gagttatcac caacgtattt ttgagaaatc
       61 gttgatagag tatcacctga ttgaacggta taagcttcgt ccgcatgagc agtcgttccc
      121 atgaagaatg cagcgccggc agccaaagtt gttccaaaaa gtaaagtttt aagtgatgtc
      181 atgaaaaatc tcctttattc gttaaaaagt tttatttgtt gtgttcaacg aggaatactt
      241 taacacgtga aaatatttca taggtaaaag aagcatgaca atttatgaca aatccacgtt
      301 ttttgtaaca gaatgatgtt cgctcgatgt gaaaaatgat gaggaatttc acataatgca
      361 gaaataatgg gattagaaca ggtgttctga tgagaaaaga aatgtataaa taacttgaaa
      421 gaaattgctt ttgttcatca ttttatttac atattgcgta tattttttgt atttttgctt
      481 gagatgttac aataaaagaa aaaggaggcg gttccaatga gtaaaagata ccagaacatc
      541 atggtagcag ttgacggatc aagacaatcg atcaaagcgt tcgctgaagc ccttgactta
      601 gcaaaggaca atgaagccca cttatttatc gtgtcaatca tcaacaaagt tgagctgacc
      661 catagtgcct atgccttttc aaaaatctat gcagatgaaa aacaaagaac agaagtagcc
      721 atgctgaaaa aaatcaatga tgccaaagag tacggcattg ctgagatcca cgcaatagtt
      781 gaaactggag atccaagaaa tttgattgcc aatgtcatcc ctggacaaga aaatattgat
      841 ttgatcgtta tgggagcgac aggaaaaggt gctatacaac aagcattagt tggatcgacc
      901 gcttcttatg tcgtatcaca tgccccttgc agtgtgttgg tcgtgaagta atgagataag
      961 ggaggaatag aaaatggttc gtcctcaaga agtccgtgcg ccaaaagaaa aaatagaaat
     1021 tttagcaatt attgaagacg gcacacaaac aaagaaggga tactcgatcg ctttagtaaa
     1081 gtggaaagga aaaaaaggtg ttgctctgag atgggatgga gataaccaac aagataaagg
     1141 attccctgtc acagctaacg gttatcatcc agcgtggttt gttctgcctg ataaatttat
     1201 ggaattatac agctatgatt atgcaagagc cgcagcatca atcaaagcat tagataaatt
     1261 aacagaagag cagaatgaaa tggaggaaaa ataaaaaaga cgaaccaatc agcctttaga
     1321 aaactgatta gttcgaggag taaaaatgaa aaaaggttat ttgggatgaa actagaataa
     1381 tgcgtataac ttaaataaaa cttaaagcaa taaaatggca agagggtgag gcaaatggaa
     1441 gcaggaaaag tattacagga agtaaaagca ctatgtgcag ataaaaaata tgaagaagcg
     1501 aaaagcctga tcgaaaagaa caaagaaaat ttggaagaaa agtacccgat cgcacaagaa
     1561 tttatagaat taaaacaagg aacgatcctt caccgattca aacatttttt tggtataaca
     1621 gaatagaaaa aacgattaaa gatcggcaga aatttgctgc atctttaatc gttttctttt
     1681 taaacatgcg agggattcaa ttctgattct tatataaaaa atagatccaa ataataagaa
     1741 aaattactga aagcgtcaat tcgatgatgt gtgttattaa tacagacgtt gtttcccaat
     1801 gcctaaaaga aaaaatttga taagtaaaat atacagcagg taaagaggcc agtaaaactg
     1861 aaaacttctt ttttgtccat tttatgtaat agaaaagaat gcttatcata ataaaaaaag
     1921 gaatataaaa aacaaattga ccgatcgcga tcatactatt gcctccgata aataaagtcc
     1981 atgatacaaa ataacacttt gtgcgaaatg gcgcaagcag ttttgtggat ttatccggta
     2041 aaatctgtat cgattttgaa attagaggag aaacttgcta taatcaaagt gaaagaagga
     2101 gtgggatttt catggatcat gtagtgttag aaatcgattt gcatttgatc aataatattc
     2161 gggtgattta ctatgttgta agtaacagtg tcgaacaacg tgtactgacg aataaaataa
     2221 atggtatttt agcaaagaaa gacgttcacc gattcaataa tggtgaagga agttattata
     2281 gtatcccagt agaaaaaatt atttatacga cagtcaaagt cagagaagat ctagatacca
     2341 aaaaagcata tgaacctatt tttacaactt attgattgac agcagatgga ggaaaaaaat
     2401 gaatccatat gaacaactta ttcaagattt gatcgatgga aaaatcgaaa agattgatgt
     2461 aaaaagagaa gaattaatgg cttttcgaga agcgtggctg aagttggaga atcgtaaata
     2521 tgtggtggga aaagcctcac tgaacggcaa tgtgacttat cattacgatc cgacacgttt
     2581 attttagtat gaagtattca gaaaagaacc aaaggaggac gatgcagcag cattgtcctc
     2641 ctttgatttt acaaaagtga aagttttact tatttgaata gatttttaaa tttgtttttg
     2701 acactgtcga tatttacatc ttttaaaaga ttttgggctt tctctttata aggtcctaat
     2761 tgttctttat gttcttcgat aaatcgtttt gcgccatcga aattgccgtt cttaatcatt
     2821 tccttgactt tttgaaataa ttcttcttga ttcattttga acacatcctt tgctatcaac
     2881 atgatttttt acatggacaa aacgagaaaa actgatttat ccacacgtca ataatatcaa
     2941 ataacgatca tttttactaa aaaaacactc gattctcgct tctaaagtag gagaaaaatc
     3001 tccaacttgg gacggatgga atttctttaa ctgacccata tactgaatat ataacaagga
     3061 ggtagaaaga tgaaagtgat taaatatttg attggactgg cggcgattag tggtattttg
     3121 ctatttggac tgaaatatta tactgaagga agttatggag aaatccctgg tatacttgat
     3181 cagctaaatc cattagttga aaaaggagag gtctatgtaa agacacaaaa accagaggaa
     3241 gtaaatgaat atggtacagc aaggtatgtg cagaaagctg ctgatgccaa tgggaaagaa
     3301 cgaacggttg aatttaatgg tctttctgtg ttaaaagaaa atcattattt gaaaattagc
     3361 aataaaggag cacacataga aacgtatgag gaagttccta gagaaaaagt tccggagaaa
     3421 gcattagcaa ttattgggta aatcagtttt tgtattaaga atacgcccga ttttattatt
     3481 cataatttaa ttatgtaaac taaatacaag tagtaaaaat aatacaataa tccccctgca
     3541 aaaagattgt tcttttacag ggggttcatt ttttcagcaa gcacatcaaa ttgggatggc
     3601 agggttcgaa cctacaattg cttgattcag agtcaagtgc cttaccagtt tggctacatc
     3661 ccatttattc aacaaaataa tcatagcact ttcctaaaaa aacgcaagtt atttttcttg
     3721 atcggatagt tgttgcttta ctcgtaaaag gcggcgtact agtttctttt ctaatccagc
     3781 aggaagggca atcagttctg ctactgacaa gacggtgtcc aataactgat attctttgac
     3841 aggttcattc ataatatgat agatgtttgc taaacgttca atatattcaa agcgagtata
     3901 ctctgttcga gcaattagaa atttcaataa atcggtggct ttctcgtact cttgatctgc
     3961 gtaataaaca agagattgac gatacaattt gatttccagt tcattgaggg tagcaggtct
     4021 gcgacgctcg ttccactcat taatagagac tttaccttga acatttccct tgcagtcacg
     4081 gacaaaaata atcggaattt catttggatc cattttttta tgtgtgaatt tttccattat
     4141 ctacgctccc ttcaaaggtt tggtatcttg agtataaggg atttttgttt gaattactag
     4201 cttttctcca aagttagcat ctgtccaccc attgcagtga aaatcgccga aaaatcgttg
     4261 atcggtactg ctcgattttt tacaccatag ggatcgttga cataaatatt ttctttgtca
     4321 tatccagtga ctacacaagc atgaacaaga ggagtgactc ttacttctcc attatttgtg
     4381 gtccaagtca taaaatcagt ttcatctggg acttcaaaat tgatagtcac agaagtccag
     4441 acaggatttc ctttagatag tgcttttttg atatcatcga gttgagcatc ggtttttgga
     4501 aaagtgtgat aatccgtttg gacgatttgc tgagcaaggg aggcaactgg gggaacatag
     4561 acgaccatag cccagtctcc gccactgata tcaccaacaa atccttcatt aggatcgcca
     4621 tgagtcccat ctgcattgaa aacagggacg taatccaatt gctcagctaa ctggttttta
     4681 gttgtttcat aaccataaaa agataaaagc atagaaagcg aagtgacttc acagccattt
     4741 tctaaagaag gagaatcaaa ctggctctct aatggaacat ctagtaaaac ttctgctttc
     4801 tcttttgtct ttttcgtttt ttgtgttgaa cttttttgtg cagtgttcat tgtatgttct
     4861 ggagaatgga tatgtaggta ataacttgta ccgcttaata aaagagcagc tgtgccccta
     4921 gaaacaatag ttttttgaac gtttttttct tcatttgaaa tctccctttt cagctgttta
     4981 tctttcctat tataaatgta tttttattgg aaatg
//
LOCUS       DAFLVO010000129         4979 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.134, whole genome shotgun sequence.
ACCESSION   DAFLVO010000129 DAFLVO010000000
VERSION     DAFLVO010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.134"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..1013)
                     /locus_tag="L1U99_002793"
     CDS             complement(<1..1013)
                     /locus_tag="L1U99_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1213294.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESE"
     gene            complement(1258..2529)
                     /locus_tag="L1U99_002794"
     CDS             complement(1258..2529)
                     /locus_tag="L1U99_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBN1213295.1"
                     /translation="MKLSTQEKQLKNVSLKIPKNKISIFTSVSGSGKSSIVFDTITQE
                     AGRQLNDTYDSFTRLFLPKYSRPEVDEIDNLSTAIVVNQKKIGGSARSTLGTITNINA
                     LFRVLFSCFATPSLGYANAYSFNDPSGMCSVCQGIGKTIAFLIGLLYFSAIDNADFVF
                     SDPFTAEVLSGIEEQAKNHGYFVLVHNVNSAEDVKTIQRNWRFEGFIVVGVRVKEFLE
                     LNNVFDGPVVYIDTHLSKETLRELEQQMNRLFVNTNDYQASTLAVEHLIHYGHEKIAF
                     LSFDYIVGEPSVIQERHQAYIDTLKKYHLTFKSHWIYNNSEFERIYQELAEFTAIVVT
                     GDYLAAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNPGNKGAIAFHQ
                     LIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            complement(2813..3760)
                     /locus_tag="L1U99_002795"
                     /pseudo
     CDS             complement(2813..3760)
                     /locus_tag="L1U99_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634498.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            3772..4245
                     /locus_tag="L1U99_002796"
     CDS             3772..4245
                     /locus_tag="L1U99_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1213296.1"
                     /translation="MRIKPIKDGEQLLFSSEENKPLYLDYVNHNLKIIIKENNLKHIT
                     LHGFRHTHCSLLFESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFM
                     SSTEEKQGSLQKVKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            complement(4418..4972)
                     /locus_tag="L1U99_002797"
     CDS             complement(4418..4972)
                     /locus_tag="L1U99_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1213297.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
BASE COUNT         1576 a          949 c          742 g         1712 t
ORIGIN      
        1 ttttcacttt ctctaacaat aatattatta gaaacaatca ctttgatcga aacatttcta
       61 acttctttta ttcgttcatt aaccatgcga actgctagtt ttccaatttc ttctgtattc
      121 acattcaccg tatttaatgc aggtgttaaa aattcagcaa cttcaatatt atcaaaactc
      181 acaatcgaaa tatcttctgg aatatgtaga ccattttttt gaagtgaacg ataaaccccc
      241 acagcaatag gatcatttcc taccatgata gcagtcggca acttatcttt agcatgtttt
      301 ttcaaaagta aatctgctgc ctgcattccg tcaagtgtgg tccagccttc taaataaatt
      361 tgactatatt tttctaatcc tttttgtttc atccacgtct cataggctat ttttcgataa
      421 tcatcatctg acacgtgttt atttccttgg ctatctaaac gaacacgtcc tcctccgata
      481 aacgcaatgt ttcggtgtcc ttttttatac aatcgatcta aatgctgatt cgttgctttt
      541 gttaaatcag tataaactgc atctacttca gcttcaatac tagggtcatc aatcactacg
      601 acattcgaat taattgctga tacttcttca atcacagaag atagcacctg cccaataatc
      661 aacacacctt gacattttag caaatcgtct tgctccaacg gtgtttctga caaacgaata
      721 attttcttca aattgacttt gctttgttct gcttcgactt gaatccctct gcgaatcgtt
      781 cgaaaatagg gatcttccaa ctcatctact tcagaaactg tcgttattaa tgcaatattt
      841 gttaaatttt ttgcaacggg actttttttg acataatgat aaaaattaac cgattctgca
      901 atctttcgtt tggtttcatc ggttactgaa agtgtcggat cctcatttag cacgcgcgat
      961 actgttgcaa tggacacacc cgcccgtttt gcaacatccc taattcctac cataatagct
     1021 cctcttttca tatttgaaag tgtttactaa catataatca tacattttga aaataagcaa
     1081 atttcgttaa aaataggcac tgtaatcata attaaaaaca agaaaaaata tccgaacaat
     1141 ttagagtaaa taatgctaat tctagtgaat ttgcgacgag gaactgctag atcacagttc
     1201 attctctcta tcgttcggat attttattgt taactatact tatttcacag agctttttta
     1261 tttgattttg tgaacagagt ctcgagaaat caattctccc tctaatagta gtacttgatt
     1321 ttttatttct tcttgtttgg ccagtccaat cagttggtga aaagcaatcg cccccttgtt
     1381 acctggattt agtcgtattg ttgtcaacgc aggatccatt aattctgcaa aagtaatatc
     1441 atcaaatcca ataatcgata attgttccat cactcgttta ttcttatttt ttaaaaattt
     1501 tactaattta gccgctaaat aatctccagt aacaacaatt gcagtaaatt cagctaattc
     1561 ttgataaatt cgctcaaatt cagagttgtt atatatccaa tgcgatttaa aggttaaatg
     1621 atatttcttt aatgtatcga tataagcttg atgtcgttct tgaataacac ttggttcacc
     1681 tacaatgtag tcaaaagaaa gaaacgctat tttctcatga ccataatgaa tcaaatgttc
     1741 cactgccaat gtactagctt ggtaatcatt tgtatttaca aataaacgat tcatttgttg
     1801 ttcaagttct cttaatgtct cttttgaaag atgcgtatca atataaacaa caggaccatc
     1861 aaaaacgtta tttaattcca aaaattcttt tacacgtaca ccaacaacaa tgaacccctc
     1921 aaaacgccaa tttctctgaa tagttttaac atcttctgct gaattaacat tatgcaccaa
     1981 tacaaaataa ccatgattct ttgcctgttc ctcaattcca gacaaaactt ctgcggtaaa
     2041 tggatcagaa aatacaaaat cagcattatc aatagccgaa aaataaagca atcctattaa
     2101 aaatgcaatc gtcttaccga ttccctgaca gacagaacac attccactag gatcattaaa
     2161 tgaataagca tttgcatatc ctaaactagg tgttgcaaaa catgaaaaca acacacgaaa
     2221 taacgcattg atgttagtaa tcgtccctaa cgttgagcgc gcactgccac caatcttctt
     2281 ttgattgacc acaatcgccg tagaaagatt atcaatctca tcaacctctg gacgactgta
     2341 tttaggtaaa aataaacggg taaaactatc ataggtgtca ttcagttgac gaccagcttc
     2401 ttgggtaata gtatcaaaaa caatcgatga ttttcctgaa ccagatacgc tggtaaaaat
     2461 actaatttta tttttgggaa ttttgagact gacattttta agttgtttct cttgcgtgga
     2521 taatttcaat atactcgttc atttggtact cccctttatt ttgaaatagt tgagaatgtt
     2581 tcaatgagac acggtatttt tggcagatgt ttagtttacc tagaaagagg tataaaaatc
     2641 aagaaaaaaa gagaggctga ctcataagta gttttattag tcgaaaatga tagtttataa
     2701 aaataggaac cgcatcaaat caacattctt tagaatggat ttgatgcgtt tttctttatt
     2761 ttttgactta tgagtcaacc tcttactctt cgtcatggat ttgattagct aattattgct
     2821 ccacttgttc acgaatgaaa tttaagtact gcggtaaaaa taaaggaatt tcttcaaagc
     2881 gtggactttg attttcatac gcttttgcat ctaggtttcc ttcccctgta gcaatttcaa
     2941 tcaataattg atttgggtca cgataataaa gtgatacaaa aaattcacga tcttttattc
     3001 ctgaatttat aaaattgcgc tcttgtaatt gtttgtcgat gcgttgtaaa tcagatttat
     3061 tttctacgcc aaacgcaaca tgatggacgc taccaatccc ttcaatggca actggattct
     3121 cacgatcttg aataatctga acttcttgat agaactgagt gtcttgattt tctaagattg
     3181 tcactcgttg atgacccgaa aagaaactga cgtattcttt gtgctaccag cctaccgaca
     3241 ataactctcg ttcagtcgca tcggaatatt gtacgcgtag ttgaatggca tcaattccta
     3301 aaatggcatg ctctgtaggg atctggtctg tgacatacgg gaaataatca tcaatatctt
     3361 caaattcgcg taagggaact aaagctaatc gtgttgcatc tggcccttca aaacgtaaga
     3421 taggtcgtcc agaaaatgat tcgattccat aatggcaaac gccttgtgtt tcaaaatata
     3481 tttcccaaaa atgcaatgat gcttcggaag gaacttttag tatcgttcgt tcaatcgtat
     3541 tggttccaaa aaactggttg ttcccttctt gtacttcaaa aaaagtcagt tcagttccca
     3601 cacggtggtg attatctgaa aaaaacaggt gatacatggt atgatcgtct tgattaattg
     3661 ttttcattag taattttaaa ccgagtatat tatgataaaa gtcaaatgtc ggtcgaataa
     3721 agcgattcac aatagaaatg tgatgaatac gtgcgggcat aatatctaaa aatgagaatc
     3781 aaacctataa aagatggtga acaacttttg ttttcatcag aagaaaataa gcccctttat
     3841 ttagactatg taaatcacaa tttgaaaatc atcattaaag agaataactt aaaacatatc
     3901 acacttcatg gttttcgtca tacccattgt agtctgctct ttgaatctgg tgcgtctgtc
     3961 aaagaagtgt atgttcgact tggacataca gatattaaaa ccactatgga tgatatatac
     4021 acccatatcg cgaaaaagca gacagaggaa acggcaattc gttttgcaga tttcatgagt
     4081 tctacagagg aaaagcaagg aagtttgcag aaggtcaaaa gtatggtcaa aaacgaaaaa
     4141 agcagactat ccctattaga tagtctgcta aacgttgagt tatcagtatt tttcttattc
     4201 cgcagcgttt gcgtttttga gaccgtattg attctctttt tttaatttca tccttttcca
     4261 acctaaaaat gttatttaat tacttagttt atataacacg aacctatacc aagtaccagt
     4321 aaccccagct tttattccgc gaactttatg aaataaaatc gttctagata aaaatagctt
     4381 ttaatctttg tctttactgt ttataaaaat ttttaaatta tacacctagt ttaaatccac
     4441 gaagtgatgc tcctatttca tcttcagtta taccaatgta cctttttgta attgcttgcg
     4501 agctatgatt aaaaataaac attaaggtag caatgtctct agttttcttg tagtagtgat
     4561 acccaaaagt ttttcttaat gtatgtgttc ctatatcatc tcgtcctaat ttttctgcta
     4621 tatctgcata tatctgatag acacgatccc ttgttatatg tcgaccttgt tgccgactcg
     4681 gaaataacca atcattttct tctttacctt cagtatataa taaaatttct tctctcaaat
     4741 tatctataaa aatcggtttt cgcttacctg ttttatgttc aacaataata ggcttacttt
     4801 tgcctcgtat atctccaact tttaatccta taatatctga catacgtaac ccattattga
     4861 ttccaaacaa aaataaaaaa ctatctcttt ccggattact tgttcttctt agccaaaact
     4921 gaaaatcttg tatctcttca tttgtcctta acggttgtac attatagctc actattgtt
//
LOCUS       DAFLVO010000130         4931 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.135, whole genome shotgun sequence.
ACCESSION   DAFLVO010000130 DAFLVO010000000
VERSION     DAFLVO010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4931
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.135"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            83..970
                     /locus_tag="L1U99_002798"
     CDS             83..970
                     /locus_tag="L1U99_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBN1213298.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1110..2036
                     /gene="cysK"
                     /locus_tag="L1U99_002799"
     CDS             1110..2036
                     /gene="cysK"
                     /locus_tag="L1U99_002799"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBN1213299.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2272..2718
                     /locus_tag="L1U99_002800"
     CDS             2272..2718
                     /locus_tag="L1U99_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBN1213300.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2991..4343
                     /locus_tag="L1U99_002801"
     CDS             2991..4343
                     /locus_tag="L1U99_002801"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HBN1213301.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4514..4801
                     /locus_tag="L1U99_002802"
     CDS             4514..4801
                     /locus_tag="L1U99_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213302.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1693 a          813 c         1030 g         1395 t
ORIGIN      
        1 ttaaaagtat aatttaatta attaagtttg ttttaagaag agaacttttt attaagtttt
       61 tttattttga ggaggaattt gaatgcaaga gctgaagacc cgcagtgccc ggcaccatag
      121 acctaaaaga aaaatggtga tcaataaaaa agcgattgct cctttaattg gaacgagtct
      181 tttagttggg ccgatgatgg ttacagcggt accgcaacat gttcatgcag atgaacaagg
      241 atctcaaaca gtcgctgatc ctcaagcgtt tatcgatcaa atcggctggt ctgcgtcaga
      301 agttgctgca agtaatgact tgtatgcttc agtcatgatc gctcaagcgt tgttggaaag
      361 tgcatatggc acttccggat tagctagtgc gccaaattat aatctattcg gtgtgaaagg
      421 aagctataac ggacaggtcg tttatatggc aaccaaagaa tatgtaaacg gacaatgggt
      481 aacgatgaat gagccattcc gaaaatattc ttcttattgg gaatccttcc aagaccatgc
      541 gaatgttctt cgttcaacca gtttttccac gggcgattat cattatgctg gcgtgtggaa
      601 aagcaataca acaagttttt atgatgcaac agcgtacttg acaggtcgtt atgctaccga
      661 tccaaattat ggggccaaat tgaactcatt gattaatact tataatttaa cccgttttga
      721 tacgccatca acaggttcgg ctacaacaac cacaagtaca acaacaacga ctactacgac
      781 gacttcaacg tcatcatctt caacaacaga tgtaaataca aataatggtc agacatatac
      841 agtcgtgtca ggtgatacgc tatgggatat tgcacaaaaa tttggcatgt ctgttgatga
      901 tctaatggcg aaaaatggca tgtctatgtc cagttattct ttattagttg gtcaagaact
      961 aaacgtttga tttagataaa aaggcaaaga aattaccata tatggtatat ctttgtcttt
     1021 tttttgctag tcaaagacga atcactcgcc ataaatgaac agattgtatt atgataagta
     1081 agaagagcaa agacaaggag gaattgaaga tgacagctat ctataactca gtcaccgaat
     1141 tgattggcaa aacgccaatc gtcaaattaa ataaaatcgt accagaagat tcagcagatg
     1201 tttttgtaaa gcttgagttt tttaatccag gaggaagtgt aaaagatcgt attgctttaa
     1261 gtatgataga aaaagcagaa cacgatggtc tactgaaacc aggtgatact atcattgaac
     1321 ctacttctgg aaatacagga atcggattgt cgatggtagg agttgcaaaa ggatataaag
     1381 taatcatcgt gatgcctgag acgatgagta tcgaaagacg tttattgatg aaagggtacg
     1441 gcgcagagtt gattttgact cctggtgcgg atggtatttc tggatcaatc agagaagcag
     1501 aacgtttggc aaaagaaaac ggctactttt taccattaca atttgaaaat gaagcaaatc
     1561 ctcttgtgca tgagaagacg actggtcctg agatacatca agcatttgga gtaaatggct
     1621 tggacgcgtt tgttgcaggt atcggtacag gaggaacgat cactggcgct ggccgagaat
     1681 taaaacgtgt gtatccgaaa atcgaattaa tcggggtaga accagcagaa tctgctattt
     1741 tagaagggaa agaagcggga cctcacaaaa tccaaggaat cggtacaggt tttgttccta
     1801 aaacactgga tacttctgtg tatgataaag tcctttctat tagtggagac gaagcgatgg
     1861 aaacagctag agaagttggg cgaaaagaag ggattttagt aggcatctca tctggcgctg
     1921 caattgctgc cgcgctaaaa gtcgcaaaag aattaggaaa aggcaagaag gtattagctg
     1981 tggttcccga caatggtgaa cgttatttat ctacagccct ttaccaagag atataaggca
     2041 cttggttttt ctccagatag gtttatgtaa aaaactttta aagatgaaaa gaacacacaa
     2101 aaatttatga tgagaaaaat tatttgaata gagacgtaga atagtgaacg cgactgtttt
     2161 acgtcttttt tcattaaaat acaataaaat tgaattttct tttcatgtta agtggatttt
     2221 aaaatgtaaa aatagtatga taagacgaga ataacaacgt ggggtgttta catggaaaat
     2281 aagttagtcg aagaggttat cgaaaagtta aaaaaagaga acattcgaat cacacctcaa
     2341 cggtacgcgg ttttagaata tttgattgaa catcattccc atccaacggc tgatgagatt
     2401 tataaagcac ttgaacatcg gtttccaaat atgagtgttg cgactgttta caataacctt
     2461 cgcttattta cttcgattgg atttgttcaa gaaatgaagt acggcgatgc ttctagccga
     2521 tttgatttca gttcaaagcg tcattatcat gtaatttgtg aaaactgcgg taagattgtt
     2581 gattttcatt acccagggct tgaagatata gaaatggctg caagcagact gactgatttt
     2641 gagattaatg aacatcggtt ggaattgtat ggactctgtc cggattgtaa agagtcagca
     2701 aaaaaggcgc aaatgtaaaa acagtttcta caagtgttat acctaaaaaa agctagctgt
     2761 gtaaaaaaaa cgctagcttt tttatttttt tgtcttttat tcacaatctt agatataaaa
     2821 gtgaatatta ttaaaataag aatcttgtag atattgggtt cttatgcttg aaaaggaatg
     2881 aaactacaaa caaacctttg tgaattcaca agcattaaac tgttgtatcc gttttatttc
     2941 tgttatagta gttttgtcga aggacaaaat gttaatcgga gggaccataa atgaaagtag
     3001 tagtaattgg ctgtactcat gcaggtactg cagctgtaaa aagtatttta aaaaatcatc
     3061 cagaagcaga agtgacagta tatgaaagaa atgacaatat ttctttctta tcttgcggta
     3121 tcgcacttta tgtcggcgga gtagtaaagg acccagcagg cttgttctac tcaaatcctg
     3181 aagaattatc ttcattagga gcaacagtta aaatggaaca cgatgtaaca gacgtcgata
     3241 cagaaaataa aacagtaacg gcaaaagatc tgaaaacagg agaaacagaa acggtttctt
     3301 atgataaatt agtgatgaca actggttcat ggcctattat cccaccgatt agtggaatcg
     3361 atgcgaaaaa tgtactccta tgcaaaaact acaatcaagc aaatgaaatt attgcacaag
     3421 cgaaagaagc aaaacgtgta gtaattgttg gtggtggata tatcggtatt gaattagtag
     3481 aagcttttgt cgaatctgga aaacaagtga cattgattga tggattagat cgcatcttga
     3541 ataaatatct agataaacca ttcacagata tcttagaaaa agaattgaca gaccgcggtg
     3601 ttactcttgc gctaggcgaa aatgttactg aatttatcac agatgaagaa ggaaaagtga
     3661 aacaagtagc tacaccaaca gatacatttg atacagatat ggtcatttta tgtgtgggct
     3721 tccgtccaaa tacaaaactg atcgaaggaa aagtagatac actgccaaac ggggcaatca
     3781 aagtgaatga atacatgcag acaagtaatc cagacatttt tgcagctgga gactctgcag
     3841 tagtcaacta caatccaagt ggcacgcaaa actatattcc tttggcaaca aatgccgttc
     3901 gtcaaggttt gcttgtggga aataacttga cagatcataa aatggcgtat cgtggtactc
     3961 aaggaacttc aggactttac ctatttggct ggacgatcgg ttcgacaggt gtgaccaaag
     4021 aaagcgcaac tttgaacgat ctagaagtcc aagcgactgt atttgaagat aattatcgtc
     4081 cagagttcat gccaactact gaaaaagtaa tgatggagct agtctatgaa aaaggaacga
     4141 atcgtatcgt aggtgctcag ttcatgtcca aatacgacat tacacaatca gcaaatacca
     4201 tgtctttagc tgttcaaaat aaaatgactg tagaagatct cgcactttca gatttcttct
     4261 tccaaccaca ttttgaccgc ccatggaatt acttgaacct acttgcacaa gcagcgctag
     4321 gcgaaatcga aactgcacaa taaagaaaaa gggttgtgac acaattttgt cacgaccctc
     4381 tgtctttttt tgtgaaaagt acaattagtt gtctttcttc gaattttttg tcacaataag
     4441 cagcaaagat aaagctgtta cataaaagaa caagcagctt tatttgattt tgaaaagaaa
     4501 ggtgagaaag aagatgaata aagaatattt tgtccaacaa gatgcatttt tagaagatta
     4561 taaaagtgct tcgaagaaat taacgatcaa tattgatgag ttggcagatc aagtactctc
     4621 tcagttgaat gaaacgcaag aggaatatta cacgatgcca gcaaatgacg ccaaagataa
     4681 tgtttctcat cgttttcctt tcagtagacg catctactca gatgaaaatg acggcacatt
     4741 gaatacagag tacacatatg aaggtcagcc atatgtgcta gaaactgatg atgatcttta
     4801 aagacagttt ttgaaaaggc cgctcatcct taagtgatga caaaaaatca tcacaattac
     4861 cgatgactgt ctctttacta tcttttaatc agaaaaaggg gttatgacaa gctttgtcaa
     4921 cccctttttt t
//
LOCUS       DAFLVO010000131         4894 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.136, whole genome shotgun sequence.
ACCESSION   DAFLVO010000131 DAFLVO010000000
VERSION     DAFLVO010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4894
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.136"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(436..1371)
                     /gene="murB"
                     /locus_tag="L1U99_002803"
     CDS             complement(436..1371)
                     /gene="murB"
                     /locus_tag="L1U99_002803"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBN1213303.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(1444..2364)
                     /locus_tag="L1U99_002804"
     CDS             complement(1444..2364)
                     /locus_tag="L1U99_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1213304.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2477..3229
                     /gene="xth"
                     /locus_tag="L1U99_002805"
     CDS             2477..3229
                     /gene="xth"
                     /locus_tag="L1U99_002805"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBN1213305.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            4093..4626
                     /locus_tag="L1U99_002806"
     CDS             4093..4626
                     /locus_tag="L1U99_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBN1213306.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT         1447 a          953 c          845 g         1649 t
ORIGIN      
        1 tcttgtttta aatttagaca aacctaatgt ttcatataac ttaggcagca ctacataatt
       61 ctttttctca aattctaaat atctagctag cagcagtttt tctctatctt cctcttctat
      121 aaggtaatcc aacttcatat cctacacctc aaaaaatgcc tcataccaat tacttgatat
      181 gcagatgaaa gttcatcttt tcacctatac tgattttatg atggattatg cttgtttttt
      241 catcagttat tctcattttt tatctttttt ttgagaatat tgcaaaaaat ggaaaaattt
      301 atgaggaaat attctatatt ttttgtttta ttgtgttaaa atgtacaaga tttgcgccat
      361 ttgcgtaaac aaccacaaaa aagagcagga cggccaccgt cctgctcttt tacttatttt
      421 aagttccatt acttattaat tggctaaact tctgcttgtt tctgatattg cttgtttttc
      481 tccaatgatc cgcacttctg tttctaaaga cacatcaaat ttttctttga ttacttcttg
      541 gatgtgcgca atcaattcaa tataatctgt cgctgtcgca tgatcgatat tgacgatgaa
      601 tccagcatgt ttttcagaga cttgtgcacc gccccatttc aggccttgca atcctgcttg
      661 ttggatcagc tgacctgtat agtgtcctac tgggcgctta aagacacttc cgcatgaagg
      721 gtattctaat ggctgttttg attgacgcaa ttcggtcaac tcatccattc ttgctttgat
      781 tgcttcataa tcccctgttt gcaaactgaa tcgagcttcc aatacgatag cacgtaattc
      841 ttggacttta ctgtgacgat aagaaaatac catttcgtct tttgtcaaag ttttcaatgt
      901 tccatcttca agcaaaagat ccacttcagc aaaaacatct ttgatctctc cgccatacgc
      961 acctgcattc atataaaccg ctccaccgac acttcccggg atgccgcaag caaattcaaa
     1021 tccagtcaat gattctgcca aagctgcata agtcgtatca atcagtgagg cacctgcttc
     1081 cgcaatgacc atcgttcctt tgacatgaat ctgtttcatt tcagtcagca tgatgactac
     1141 accgcgaatc ccgccatctt gaacgatcag attgcttgca tttcctaata ccatccaagg
     1201 tatatcatgg attcggcaat aatcgatgat ttgctttact tcttcttgtt ttttcgggaa
     1261 tgcaaggaca tcagctggtc cacctgtttt cgtaaacgta tagttcatca atggttcatc
     1321 aaacaatata gtaatcgtgg ctaagctttc aactatttct tctttattca ctgaggattt
     1381 tcctttcttt tctcaaacgt cctcattatt ctatcacgct taatacaatc ttgccagtct
     1441 tgttcaaagt tgatgacggt agtgatcttt aagcacttcc tcacataatt catgacttct
     1501 tacaacttct ttttgtttaa gcaattctgt ttccgattta cctaaacgga tctgagaaaa
     1561 gaaggcctct accattggct caaacccgcg tttgactagc gtgtttgtcc agtcgccaaa
     1621 ttctttcact ttttttccat cagcatcttg aatgacaagc tgggtcagat cgtttacttc
     1681 ataagtacca tttttacttg ttacttgata tttttctata ttagcgccac ttgctaaatc
     1741 catcgttaaa atagccgttt gattttgtgt ttctaattgt aaaatggcat attccaaaaa
     1801 ttcctttgtt tctcttatct ggtattttgt tctcaaaatg ggttcatcta ataaatacac
     1861 agctgtatca ataagatgta aaaacaaatc ataaaggacg aactctgtcg tttcttttgc
     1921 cgctattcga tttttttgca ggtggatcaa ccgcttatct gggatacgtt tcaattcttc
     1981 taccatagga gcaaagcgcc ggttgaaacc gatcatcaaa attatttggt tcttatcagc
     2041 taattcttgc aattcacgaa cttcatttag atggacactc agtggtttgt caatataaac
     2101 atggatacca ttttctagac attttttggc taattcataa tgtacttttg ttgctgcgtg
     2161 gatcatacat gcttcgattt tttcttctaa aagctcatcg atcgtttcat atagatgttg
     2221 gaacccgtac tctttttgaa ttctttcttt tgtttcttta tttcttgttg caaaataaaa
     2281 atcaagtgtt ccttgttttt tcgcataagt tggtaaatat gctttttctg cgatattccc
     2341 tacaccgatt acaccaatct tcatctactt tcctcctgga tcatttagtt actttcatct
     2401 tacaccattt ttttctaaaa tgaggtacaa tagtatcgca aaggtaagga aattaattcg
     2461 aaggagtgtg cttttattga aatttatctc ttggaacgta aacgggcttc gtgccatcgt
     2521 aaataaaaat tttttagaag tttttcatga gttagacgcc gattttttct gtctgcagga
     2581 aacgaaactc caagcaggac aaattgattt agatcttcca ggttattatc aatattggaa
     2641 ttacgcggaa cgaaaaggct attccggcac agcgattttt gctaaaaaac cagcattgaa
     2701 tgccacttac ggaatgggta tcgatatcca tgatacagaa ggccgtctga ttactttgga
     2761 atattccgat ttctttcttg taacctgtta cacgccaaat tctcaaagcg aattaaaacg
     2821 tttagattac cgattagaat gggaagaagc cttttataat tatttggaaa atctaaaaaa
     2881 acaaaaacca gtcatcgtgt gtggggatct aaatgtcgct catcaaaaga ttgatttgaa
     2941 aaactggaaa acgaatcaaa aaaatgctgg attcactcca gaagaaagag cggctctttc
     3001 tcgactgttg gataacgggt ttatcgatac attccgttat ttttatccaa cccaggaagg
     3061 tgtctactct tggtggaact accgattcaa ttcaaggaaa aacaatgctg gttggcggat
     3121 cgattacttt ttgacgagca aagatttaga gccaggacta gctgatgcaa agatccatac
     3181 ggacattatg ggcagtgatc attgtccagt agaattagat ttgaaataaa gaggttgtga
     3241 aaaagtcgtt tagtttcgag tattaagaaa aattttgtga aaatggcttt ccacattttg
     3301 cataaatttg gcataatacc gagaaactgg cttttgaaca ctgtttatcg agagattgtg
     3361 aaaaagctgt cctgcatcaa gtaataagaa cagccaaaca aaaatagttc ctcatatttt
     3421 tcgtttggtt gggcttatta ccgcagatac aagcttttga acaccgttta ttaagaggtt
     3481 gtgaaaaagc tgcactgcat caagtaataa gaacagccaa acaaaaatag ttcctcatat
     3541 ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt ttattaagag
     3601 gttgtgaaaa agctgcactg catcaagtaa taagaacagc caaacaaaaa tagttcctca
     3661 tatttttcgt ttggttggac ttattaccgc agatgcaagc ttttgaacac cgtttattga
     3721 gaagttgtga aatcagcgtc ctgacctgag tattagagaa acaaatggca aaatagttcc
     3781 tcatattttg ctattttttg agctaatacc gagggtcagc tgattgaaca ccgtttagtg
     3841 gagaagttgt gaaaaagtcg cctactttcg agtcgtaaga aatttttttg aaaatggttc
     3901 ctcacaactt tgcataaatt tgacttaata ccgagaagtc atgatcccca tctaactcca
     3961 aatcacaagg aatgagttca aaaactagct tttctcaaca aatattacat aaaaaattct
     4021 atgttttttg ttaaatttat ttgctttttt caaaagtatg ttacagtaat ttcccaagga
     4081 ggttttacag aaatgaattt tgttgccatg gattttgaaa ctgccaatca tcagccttat
     4141 agtgcttgtt ctcttgcgct agtcatggta aaaaatagcc agatcgttga tgaattctat
     4201 acattgatac agcctgagac tccttttttc tggcgaaatg tccaaattca cggaatccat
     4261 caagaagacg tacgcaatgc gccgaaattc ccagaagtct ggcaaactat ccaaccatat
     4321 tttcaaaaaa atcgtttagt cgttgcacat aatgctgctt ttgatacaaa ggtcttagcg
     4381 ggatgcttag attattatca tcttgaacag cctaattatc tttctttatg tacagtgaaa
     4441 agtagccgtc gcctgtttcc tgaatttcca aatcatcgat tgaacactgt gtgcgaaaat
     4501 ttgaacatcc aattagatca tcaccatgat gcattggaag atagtcgtgc atgtgcggaa
     4561 atcctgcttt atcaagaaaa aaaattcggg acagatccat tgaaaaaact tgtgactata
     4621 aagtaaaaga atacttatga aacacacaaa gaggtcgtga gcctgccgtt tcactccgag
     4681 tcacaaggag caatttcaaa aaatagcttc tcatgtttat taaatattgt gactggtgac
     4741 cgaggagctg gcaggagaac accgtttatt ggagaggttg tgaaaaagct gttctgcatc
     4801 aagtaataag aacagccaaa caaaaatagc ttctcatatt tttcatttgg ttggacttat
     4861 taccgcagat gcaagctttt ggacaccgtt tacc
//
LOCUS       DAFLVO010000132         4843 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.137, whole genome shotgun sequence.
ACCESSION   DAFLVO010000132 DAFLVO010000000
VERSION     DAFLVO010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4843
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.137"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(69..1679)
                     /locus_tag="L1U99_002807"
     CDS             complement(69..1679)
                     /locus_tag="L1U99_002807"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HBN1213307.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(2872..4212)
                     /gene="glnA"
                     /locus_tag="L1U99_002808"
     CDS             complement(2872..4212)
                     /gene="glnA"
                     /locus_tag="L1U99_002808"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HBN1213308.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            complement(4240..4632)
                     /locus_tag="L1U99_002809"
     CDS             complement(4240..4632)
                     /locus_tag="L1U99_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBN1213309.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
BASE COUNT         1421 a         1044 c          795 g         1583 t
ORIGIN      
        1 agaaaagtga caagaaaatt gcttatcccc ttctcttgct acttttctct ttctatcaag
       61 ttcaaaaatt attttgtttc gtgatctgct aatgatgctc cgacaaatgc tttgattaat
      121 ttttgcgggc gatttggacg agaaatcaat tctgggtgga attggcatcc cacaaagaat
      181 tttttctctg gcagctctac gatttctact aaacggttat ctggtgagac acctgaaaag
      241 actagccctt gttcttcaaa caattgacga tatttgttat tgaactcata gcggtgacgg
      301 tgacgttctt gcacaacatc ggctccatca tatgcttcag ccgtcttcgt tccttttttg
      361 attttacatg ggtataatcc aaggcgtaaa gttccaccca aattctcgat gttttcctga
      421 tcagccatta aatcaataat attgtttgct gtatctggat tcgtttcagc tgatgacgca
      481 tcttctaatc caacgacgtt acgtgcaaat tcgacacaag ccatctgcat accaagacaa
      541 atacctaaaa acggaacgtc attttcgcga gcataacgaa tcgcttcgat tttcccttct
      601 actccgcgat caccaaatcc accaggaacc aagattccat ctgcgtcttt caaacgttct
      661 tctacatttt ctctcgttaa ttcttgtgct ttgatccaat cgatctcgat gtctgaatta
      721 taggcgaaac cagaatgttt caatgcttca actactgaga tatatgcatc tggtaactcg
      781 acatatttac cgacaagcgc aatccgtact tttttcttca agttcaagac acgttcttct
      841 aattctttcc attctgtcat gtctgcttct ggtgtatcta gttttaaatg gtcgcaaaca
      901 atttgatcca ttccttgtgc ttgtaaaact aatgggatgg agtaaagtgt atctacatct
      961 ggcgactcga taactgcttc tggttcgaca tcacaaaatt gtgccaattt gtttttcacg
     1021 ctttgagaaa caggttgctc tgtacgtacc accaaaatat tcggttggat acctaaacca
     1081 cgtagctctt ttacactgtg ctgcgttggt ttagttttca tttctccagc agctttcaag
     1141 taaggaatca atgttgtatg gatatacata acattatctg taccgacatc tgctttcatt
     1201 tgacgaagtg cttcaaggaa tggcaaagat tctatatccc ctactgttcc ccctacttct
     1261 gtaatgatca catctgaatc agtcatttta gctgctcgca tgattttttc tttgatctca
     1321 tttgtaatat gaggaataac ttgaacagtt gctcccaagt attcgccctt acgttcttta
     1381 cgcaaaactt cagaatagat ttttcctgtc gtcacgttgg agtatttgtt caaattgatg
     1441 tcaataaaac gttcgtagtg gcccagatcc aaatctgttt cagcaccatc atctgttacg
     1501 aatacttctc cgtgctgata tgggctcatc gtccccggat ccacgttgat gtatggatca
     1561 aatttttgga tagttacttt taagccgcgg tttttcaata agcgtcctaa agaagctgca
     1621 acaatccctt ttccgattga tgaaacgaca ccgccggtca caaaaatata ttttgtcata
     1681 agttcaaaaa ctccttttta atttatgtgc aggaaaagtc tcagacaata aacaaagctc
     1741 cctattcttc aataagaata gggagccgaa atttctgtaa acttctgacc ctctaaaagg
     1801 gtgcccaagg tgtataatac aagctgacta agggaaagtc aagtactcaa atgaatacta
     1861 tccgcttaca attttttctt tttcgatatc ctttgagaaa ttatttctta agtcctttat
     1921 gagtgcaaaa aaaatttaac ccacataata agcttgatat aaacatagct aacgttaaac
     1981 ctaagcaaat cagaaaatcg ttactgaaaa attttaagtg aaataataga taaaaaaata
     2041 aaacaaacat tatgatagat aatatcccac ctaacaaaga actacttttt cctacttgca
     2101 gcaacagttt atatagctta tcgtagaaac aatctttttc tttcaccctt atttacctcc
     2161 tttacgtaaa aaacgtagtc cacagttctc ggatttttgg catatctttt ctattaaata
     2221 atatcaaaaa caaaacaatt ccactaattt tttcaaagat gacctttttt tcaacaaaag
     2281 tgccttgtag ggattcattg aaggtaacga atcacataag taaaaaataa ggagatgcga
     2341 caaaagtcgt gcctccttat ttctaaataa acggtgttct cctgccaact cctcggtcac
     2401 aagtcacaat atccatcaaa catgagaagc tgtttttgaa attatttctt gtgattcgga
     2461 gttaaatggt aggctcacaa cctctggata aacggtattc aaaagccagt ttctcggtat
     2521 taagccaaat ttatgcaaaa atgtagaaag ccattttcac aaaatttttc ttaatactcg
     2581 aaactaaacg tctttttcaa aacctcttgg taaacggtgt tcaaaagctt gcatctgcgg
     2641 taataagttc agccaattca aaaacaagaa aagctgtttt tgcttggcta ttcttattac
     2701 ttgttgcagg gcagcttttt cacaacctct ccactaaacg gtgttcaatc agctgaccct
     2761 cggtattagc tcaaaaaacg gcaaaatatg aggaactatt tttccgttag tttctctaat
     2821 actcaggtca aaacgctgat ttcacagcct ctaattcacg gtattcctgt tttaataaag
     2881 ttctagatat tgttctcttt cccactcgga aacagtttgt ctgaatgccg cccattcgag
     2941 acgttttgct tcaacaaaat ttgagaagat atgttgtcct aatgcgtcaa tcattacatt
     3001 atccttacgc aattctttga tagcattatg gatagttgaa ggtaagtcct ggatatgtgc
     3061 agcttctctt tcttcctcat ccattacata aatgttacgg tcaacagctg ctggcggtgt
     3121 gatctgatta cggataccgt ctagtcctgc ttgcaacaat actgccattg ccaagtatgg
     3181 gtttgcagat ggatcaactg accgcaattc caaacgtgtg gataaaccgc gagattctgg
     3241 tacacgtact aatggcgaac gattacggcc actccatgcg acataaacag gcgcttcata
     3301 acctggaacg agacgtttat aagaattgac tgttggattg caaacggctg tgtaggcacg
     3361 agcatgtttc agcaaaccac ctaagaaatg ataagctgtt tcacttagtt ccaattcacc
     3421 gtctttatca tagaaaacat ttccttcatc attgaacaaa gacatattgc aatgcatacc
     3481 agaaccattg atcccaaata acggtttcgg catgaaagtc gcgtgaagtc catgcttgcg
     3541 tgcaatcgtt ttgacaacga gcttgaaggt ttggatatta tcacaagcat ctaccacatc
     3601 tgcatattta aagtcaattt catgctgtcc tggcgctact tcatgatgtg aagcttccac
     3661 ttcaaagcct agactttcta attccaacac gatgtcacgg cggcaatttt cacctaaatc
     3721 tgttggtgca aaatcaaaat aaccaccttt atcattcaag gtcgttgtga tcccaccgtc
     3781 ttcgtctaat ttaaataaga agaattctgg ttcaggtcct aaattgaaag aggtaaaacc
     3841 aaggtcgcgc atatctttca atgctcgttt caaattcccg cgaggatcgc cggcaaatgg
     3901 tgtcccatcc ggattataga tatcacaaat taaacgagca acttttccat gagcactttc
     3961 ccacgggaag atcatccaag tggagagatc tggatacaaa tacatatcgc tttcttcaat
     4021 tcgaacaaat ccttcaatcg aagaaccgtc aaacatcatt ttattttcta atactttgtc
     4081 gatctggctc actggaactt ctacattttt gatcgtacct aagatgtctg tgaacatcaa
     4141 tcgtaaaaat cgtacgtttt cttcctcaat gattcgtttg atttcttcac ctgttatctg
     4201 tttctttacc atggtatccc tcttcctttt ttaatttatt cagtcaaaga attgtctttg
     4261 caatccttgc gactgataat gacctgtttt gcttaaccca ccttgcgcca aaatctcatc
     4321 acgaaaaatt tgtcgaacgt catgatctgt caacggcttc ttgttttttg cttcttgttt
     4381 tttcgcctgt gccatttcgt atacacgttt gatcccagcc atattcaatc cctctgaaag
     4441 atagtcttta atctcaagca acatatcaat atcattcagc gaatacatac gtcggtttcc
     4501 ttcgcttcgt tccggatgaa ctaaatcttg ttcttcataa tagcgaattt gccgagcaga
     4561 caaatcagtc agcttcataa ctgtaccaat tggaaatacg gacatagatc ggcgcaattc
     4621 cttttctccc atcagacgtc ccctttcgtt ttataagttg gctaaagtgt accaattaaa
     4681 aaaaatattg tcaactgcat atgttaggtt ttctaacatg agatctctat tttttataaa
     4741 ataacaaaaa aataagaaca caaaaaaggt atctagttga ttttcgtacc agataccttt
     4801 tattttttat tatactgtac tatcctttat tagtgttttt att
//
LOCUS       DAFLVO010000133         4577 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.138, whole genome shotgun sequence.
ACCESSION   DAFLVO010000133 DAFLVO010000000
VERSION     DAFLVO010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4577
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.138"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..607
                     /locus_tag="L1U99_002810"
     CDS             <1..607
                     /locus_tag="L1U99_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1213310.1"
                     /translation="KYKNSYVRNMYGIFQMSLDRAVVLGLLEKNPAKVIGNVKKRKTT
                     VDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVMRLGEATALTWKDIDFENKNL
                     RVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFLKAWKERQVSIGGMSFVLSYN
                     GTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLLISQ"
     gene            complement(891..1976)
                     /gene="xerS"
                     /locus_tag="L1U99_002811"
     CDS             complement(891..1976)
                     /gene="xerS"
                     /locus_tag="L1U99_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HBN1213311.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            2310..2543
                     /locus_tag="L1U99_002812"
     CDS             2310..2543
                     /locus_tag="L1U99_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HBN1213312.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            2540..2947
                     /locus_tag="L1U99_002813"
     CDS             2540..2947
                     /locus_tag="L1U99_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBN1213313.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(4084..>4577)
                     /locus_tag="L1U99_002814"
     CDS             complement(4084..>4577)
                     /locus_tag="L1U99_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HBN1213314.1"
                     /translation="LKKEINRTYTKYILEFETIPEELKDKRVEEVDRTPAENLAYQVG
                     WTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKELEEILNRNID
                     DINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTFRTKIRKWKR
                     LAL"
BASE COUNT         1520 a          730 c          740 g         1587 t
ORIGIN      
        1 caaatataaa aattcttatg taagaaacat gtatgggatt tttcagatgt cattagatcg
       61 agcagttgtt ttgggactac ttgaaaaaaa tcctgcaaaa gttattggaa atgtgaagaa
      121 aaggaaaact acagttgatt tttggacaaa agaagaattt acaaaagtta tttcaacttt
      181 ttatattgat gatttgtacc aacattttgg ttttatttgt atgtggttac tttttatgac
      241 cgttatgcgt ttgggagaag ccactgcatt aacttggaaa gatattgatt ttgaaaataa
      301 aaacttgcgt gtgaataaaa cactctatta taagagagcc aaaacctatg agtttgtaga
      361 acccgaaacg gcttctagta ttcgtacaat cgaactagac gacaatacaa ttaccttttt
      421 aaaagcttgg aaggagcgtc aagtttcaat aggaggcatg tcgtttgtac tttcttataa
      481 tggaacacct actcagaaat atacaatccg tcatattatg agaagacatg caacgatcgt
      541 tggtgttcat ataatccgca tacacggatt aaggcatagt catgcttctt tgcttatatc
      601 acaataaaaa gatgcacttc gaattaaaga aaggttaaaa catgctgatg tacaaacgac
      661 tttaggaact tatggtcatt tgtatctaaa ttcattgaga gagataacaa atgatcccac
      721 agattatatc caaactaatt tttctaaaat caaaccgaca cctatttacg ataataaaaa
      781 ataaatgata aacaaaagta ggatcacacc aaaagaaaca cactagaaaa actataatac
      841 aggcttttct agcgtgttgt ttcttatttc cgcctattta tacattatac tcataaagca
      901 tttaatgcat cgatcgtagc cgcattgtct atatgggtat ataaagttgt tgtattggta
      961 cttgaatgtc ccaattgttg ggcagttaat accaatgaat ttgtctgttg gtagagtcta
     1021 gtagctaatg tatgacgcag tttgtgaggg ctgacttgaa ttctaaagcc ttttgaatat
     1081 tttgctacca tccgttcgat tgcaataccg gatatacgct tggcttctcc ttggtaaatt
     1141 gctagaaata aagctttttc gttttctgtt actttatatc gttctttccg aatagctaga
     1201 taattagcta aatattccat tgcgaatgct gctatattga cagcatctct tttatttcct
     1261 tttctagtta ctaccacatt attcttatct aaagataggt catctaaatt aatatttata
     1321 acctcggaga gtctcaatcc agatcctaaa atcagtgcat tgatcgccag gtctctttct
     1381 acatctcgtt gataatagat caaagctcgt ttactcaaag tatttttata ttcattggca
     1441 atataatcta gataattttg tgtatcctta tctagaaata attttttctc aatggcattg
     1501 gcacgtgcag ctaacgtagt tttatctgtg atggttgcta cttgatccat aggattattg
     1561 tctaagtatg gttttcctag aggattattg gaacttttcg aaagatattt aaatagaacc
     1621 tttaatgccg tgatatttct attgatagta gaagtagata gacctaagtt attattatct
     1681 ttgagcttag tttttgttgt ctcttttttt acattttctt ttgtgcgacg tttcaaatga
     1741 gatttgtaca agtttaggtc ataggcagtt aactgtctta tcgaggtgat agaagtatca
     1801 ggaacgatag actcactcag aagccattca taaaagagct tataattttt tagatattct
     1861 aaagtggttc gaggtgattg atctttatcc tcacgatctt gaacaaaatc ttttatataa
     1921 tcgggcatat gaagtatgat tgtatctatt ttttgatata tttctgtatt tttcatgtca
     1981 ttcatccttt caataagtag gggagaagag tatctctata attggactat accaattata
     2041 gaatgttttg tcaattggta tgctctaaaa tttattaatt tgtttcaaaa aaagcatata
     2101 aacaggtata cgtttaataa tttaaaataa atggtataca taaataggga aggaaataga
     2161 agggagcaat ctaaattttt tgaattttct taattaatta tatagaaaga acaatctttc
     2221 tatagagtta gacatgagag ggactatgct tgatttaaaa tcaacaagcg tatatactgt
     2281 atatacaaag aaaaaggagg gagaagacta tggcaattaa agaaagaaaa tttagggaag
     2341 tggggaactc agtagtatta actatttcaa aggagtttct taaagaaaat gggttaaatc
     2401 ccggagatac ggttttttta gatgaagaaa aacttcgagc ggcaattaca aaaaaacaag
     2461 ccttatctga tgaaattgat ttagcaatat ctcaagcatt aactgaatat gatactactt
     2521 ttagagagct tgtcgataaa tgagtattca ttacctagaa gccaaagata ttataaaaat
     2581 gaatgtaatc caaataaaaa aatactctcc taatgaaccc cttggtgtaa aggatgcgaa
     2641 tgctttagaa atgtgtgtag ggcaacttcg agcctcagct tttggtgaag aggtttatcc
     2701 ttcgatttat gaaaaagcag ctatcctact tatacaattg ataaagaaac atccttttca
     2761 caatgcaaat aaacgtactg ctttcttagc tacttttgtc tttttgaaaa tcaatggaca
     2821 gcttttagct attgatcaaa aagatgctgt aaatttagcg gtatatattg ctacgtatga
     2881 taaggatttc gatcaactaa aatatgaagt gatcaacact ataaagacac atacgcagcc
     2941 catttaagga gttactgtat gtgtctttat agggttatta gctgctatag cgaaataatt
     3001 gaagtaaatt acaaatagct ataattcaaa tccaactata tagaaaacgt aaattttcta
     3061 tatagttgga ttaagataac gactatttat tttatcatat ttttactata ccctatactt
     3121 ttacttggta tatttatgaa taatcgcaaa tttaccccta tactactagt ttgtaagtta
     3181 gattaataaa aatactaaag ttatttgttc ttttattaaa tacacctaca acttataaat
     3241 tgatggtatt tagataacac gaaagaataa aaataacagc tgatagtaaa gtttgttgac
     3301 gattgctact caatcgaaag tgagttagtg cgtatgaact tgcttctgaa aacttatgaa
     3361 atgaaagacc ttttacatct tgcagaaatc gttactggga ttaaactaag caataaaaac
     3421 taatgttccc ctcattcttt gaacttctac tatttgattt atttattctg ataaatgacg
     3481 atttcacctt caggatcttc aaatcccgta tagaatttat ttaagatctc ttcagtatca
     3541 gtaataggat aggcgatagg ccacataccc tttgatggtt agaataaact gctcaaaatc
     3601 tgtatcgtat gttggcttta gcatattaac aaaggctatc tccaaattat aaaccataag
     3661 cgttgaatcg ttcttaacaa tttcaattct tcctaaccca aagtcagaag atataattac
     3721 cggacttgcc ttacccttca tgtgggttgt tgagattcca tatttaaagg gaattgtcgg
     3781 tactatcggc ggtctgaaaa acatcccaaa aataaaaaaa tctttcccct gctagtctcc
     3841 taagtccctt tgtagcggat atggcaccat aatctcattt tatcgaagtg agtcatggtt
     3901 tatctgttgg ccaaccaaaa ttgatacaat ctaacgatgc accctctacg gcattctagg
     3961 ggagtgcact tgcattcacc caataaaaac cggcagttag caaagaactt atgtagtcgt
     4021 atgttcttac tgttaacata caagaggtct cctttccaca attgcttagc agtaaacggg
     4081 aatttacaaa gctaatctct tccattttct tatctttgtt ctaaaagtcc caaatggagc
     4141 aactgtattt acatgaataa atttatatac ttcccataca gccgttttgg ttgcctcgtc
     4201 tgcccatttt cttttgtgtg cagtgaatag atcttcatca ctcattgaat caatcatcat
     4261 gttaatatca tcaatattac gattgagaat ttcctctaat tctttcaatg gtagatgtgc
     4321 ataggtattt gtaaaccact tatataactc tcctaactga ttccatttaa attgatcaga
     4381 aggcgtttta acagataatc catttctttc atcattttcc cattttagaa ttaaattcgt
     4441 ccaaccaact tgatatgcta aattttcagc aggtgttcta tccacttcct caactctttt
     4501 atccttcaat tcttcaggaa tagtttcaaa ttctaaaata tatttagtat aagtcctatt
     4561 tatttctttt tttaatt
//
LOCUS       DAFLVO010000134         4569 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.139, whole genome shotgun sequence.
ACCESSION   DAFLVO010000134 DAFLVO010000000
VERSION     DAFLVO010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.139"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            118..2058
                     /locus_tag="L1U99_002815"
     CDS             118..2058
                     /locus_tag="L1U99_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HBN1213315.1"
                     /translation="MKKIIAITSCPVGIAHTYMAAENLEKAGKAVGAEVKVETHGSIG
                     IENELTARDIEEAAGVIIAADTKIDKSRFGGKPLITVGVQEGIHHADELVRDILAGKA
                     PVYKSTEAIISSENKSESENLGKKIYKSLMNGVSYMVPFVVTGGLLIAISLTLGGTAT
                     PEGIKIPEGTIWATMNSIGSIAMGLMVPILSAFIAQSIADRPGLVPGFVGGMLAANGA
                     LYGSDANAGFLGGIITGFLAGFIALGIKKVRVPKALQSIMPIIVIPILGSLAVGFVFI
                     YVIGEPVALLFSSLTHFLAGMQGGSEIVLAMILGAMIAFDMGGPFNKVAFLFGSGLIA
                     EGNYSIMGPIAVAICIPPLALGLASLILKTKFTKTEREAGKASLAMGLFGITEGAIPF
                     ASTDPLRVIPSIVIGAMTGSVIAMLSGVTDHVAHGGPIVAVLGAVDHVAMFFVAVIAG
                     IAVTVLMLRILKPTLQQTAVAAANGVTVADLSETETSDVYTKTETFDSITDIMSDEAI
                     VLGETATTKDGVIEDLVQRLEKTAAITDKTRFKEVIYDREHESTTGIGMGIAIPHGKS
                     AYVLKPTVAFARSQSGVDWHSLDGKPAHMIFMIAVPENSQGDMHLKILQRLSRKLMDD
                     DFRQALMEAPDKTTVHQLLSEM"
     gene            2145..4067
                     /locus_tag="L1U99_002816"
     CDS             2145..4067
                     /locus_tag="L1U99_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBN1213316.1"
                     /translation="MNQRQQSLIYQLSENNNYITTKKLAEHFHVSERTIHSDLNTIET
                     WLRDKHLPLMFERKKGTGILLNGLPHEREQLKRALNEETQTEMDKKQLRQLLIFHLLV
                     AKDGFSLEELSEKLYVGKRTIRKELTELQSFFEYHHLQLVSKTKLGTFLKGDEQEKRQ
                     LLVKTLRNMQKEDPQSPSLKEFFAKDTLKVIQHTLQDVFYENHLEQPNGLASVEIHIY
                     FMLERMKQYQKVKLSKDENEVVEHTQAQKLSSQILAKLATIYPIEFSPDEINYLALRI
                     ANLFTNSQAATRFQKESSALADHLIEQVEQFLGYSLKEDQLLKQNLRSHLSSTYFRLH
                     YGLQISNPLTKNVFSTYTQLFLVLQLILEDYFEKENFYVPQEETAYLTIHFQAAIERH
                     KHQKSRRYQTVLVSEYSKAMATFLEARLNRELPELTIMDLVEYKPELKRQDFPSVDFI
                     LATLPFKHISIPVIEISPMITETDLAYLTKYMLEHVPIKKKKTFDLASFTHPFLIFPQ
                     LERTDPADILNFMGNVLVEHHYVEPEFIDSVLERDSHSSTRVAPFVTIPHGNPLYVKH
                     SMISIATMKEPVLWHGEQIRIVLLLAIKKNDLKHAEFKKIFSVIHYLEKQPEQMAQLM
                     QSNHPLEILTLLSSYE"
     gene            complement(4347..>4569)
                     /locus_tag="L1U99_002817"
     CDS             complement(4347..>4569)
                     /locus_tag="L1U99_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HBN1213317.1"
                     /translation="RDYFTQADLIITLCGDAKDKCPAVPNNHEHLHWDLKDPAQAVGS
                     EEEILTEFRKVREGIKRKVLDLNQRTSIV"
BASE COUNT         1512 a          774 c          939 g         1344 t
ORIGIN      
        1 aattttttta gcgaaatttc tatttattcc aagaatttca gttattacgg aatcattttg
       61 tgcttaataa aaagaaaccg tttttatata ctataaatgt agaaaggcgg taggaaaatg
      121 aaaaaaatta ttgcaatcac atcctgtcca gttggtattg cccatacata catggcagca
      181 gaaaacttag agaaagcggg gaaagcagtt ggcgccgagg taaaagtcga aacacatggt
      241 tccatcggta ttgaaaatga attgactgca agagatatcg aagaagcagc tggtgtaatc
      301 atcgcagcag atactaaaat agataaatca cgattcggcg gtaaaccttt gataaccgta
      361 ggtgtgcaag aaggaatcca ccatgcagat gagttggtga gagatatttt agcaggaaaa
      421 gcgccagtct ataaaagtac ggaggcaatt atttcttccg aaaataaaag tgaatcagaa
      481 aatttaggta aaaaaatcta taagagtttg atgaatggcg tttcgtacat ggtacctttc
      541 gtagttacag gagggttatt gatcgcgatt tctttaacat taggaggaac agctacacct
      601 gaagggatca agataccaga aggaacgatt tgggcaacga tgaatagtat cggaagtatc
      661 gctatggggt tgatggttcc aattctatct gcatttattg cgcaaagtat tgcagatcgt
      721 ccaggacttg ttcctggatt tgttggtggg atgttagcgg caaacggagc attatatggt
      781 agtgatgcga atgcgggatt cttaggcggg atcatcactg gatttttagc aggattcatt
      841 gctttaggaa tcaagaaagt gcgagtaccg aaagctttac aatcgatcat gccaattatt
      901 gttatcccaa ttttaggatc attggcagtt ggttttgtgt ttatctatgt tattggagaa
      961 ccagtagctc ttctatttag ttcattgact cactttttag cagggatgca aggaggaagt
     1021 gaaattgttc tagctatgat cttaggagcg atgattgctt ttgatatggg ggggccgttc
     1081 aataaagtag cctttttgtt cggatctggc ttgattgcag aaggcaatta ttccattatg
     1141 gggccaattg ctgtagctat ctgtatccct ccattagcat tggggctggc atcattgatt
     1201 ttaaaaacca aatttacgaa aacagaacga gaagctggta aggcgtcctt agcaatggga
     1261 ctgtttggga ttacagaagg cgctattccg tttgcttcaa cagatccact acgggtgatt
     1321 ccaagcattg taatcggggc aatgacagga agtgtgatcg cgatgctttc aggagtgaca
     1381 gatcatgtag ctcatggcgg tccgatcgta gcggttttag gagcagtgga tcacgtagcc
     1441 atgttttttg tagcagtgat tgctggtatt gctgtaaccg tgctaatgtt aagaatcctt
     1501 aaaccgacat tacaacaaac tgcggttgct gcagcaaatg gtgtgacagt agcagatcta
     1561 tcagagactg aaacaagtga tgtttatacg aaaactgaaa cttttgattc tatcacggat
     1621 attatgtcag atgaagcaat cgttttaggt gaaacagcaa caacaaaaga cggagtaatc
     1681 gaagatttag tccaacgttt agaaaaaaca gcggcgatca cagataaaac cagatttaaa
     1741 gaagtcatct atgatagaga acatgaaagt acaacgggaa tcggtatggg gattgctatt
     1801 ccacatggaa aatcagctta tgttcttaaa ccaacagtgg catttgccag aagtcaatct
     1861 ggggtagatt ggcattcttt agatggaaaa cctgcacata tgatctttat gattgctgta
     1921 cctgaaaaca gccaaggtga tatgcacttg aaaatactgc aacgtctatc acgtaaattg
     1981 atggatgatg acttccgtca agcactgatg gaagcgccag ataaaacaac agttcaccaa
     2041 ttattaagcg aaatgtaaca taagatgaaa aatcgaccgt gatgagacat aatagatgtg
     2101 ttatcatgat cgatttttta tttagaaggg agtttctgca cattatgaat cagcgtcagc
     2161 aatctttgat ctatcaatta agtgagaaca ataattatat aacaacaaaa aagctagcag
     2221 agcatttcca tgtgtcagaa agaacgattc atagcgattt gaataccatt gaaacttggt
     2281 tgagagacaa acatctgcct ttaatgtttg aaagaaaaaa aggtacaggt atcttgttga
     2341 atggtctgcc tcacgaaagg gaacaactga aacgagcgct taatgaagag actcaaacag
     2401 aaatggataa aaaacagctt cgtcagttat tgattttcca tctgctagta gcaaaagacg
     2461 gatttagtct tgaagaactt tcagaaaaac tatatgttgg aaaacgtacg attcgtaaag
     2521 aattgacaga gttgcaaagc ttttttgagt atcaccattt acagctagta tccaaaacaa
     2581 aactaggaac ttttcttaaa ggcgatgaac aagaaaaaag acagttgctt gttaagacat
     2641 tacgaaatat gcagaaagaa gatccacaaa gtccgtcgtt gaaagaattc ttcgctaaag
     2701 atacattaaa agttatccaa catacattac aagatgtttt ttatgaaaac catttagaac
     2761 agccgaatgg actggctagt gtggagattc acatctactt tatgctcgag cgaatgaaac
     2821 agtaccagaa agtgaaatta agtaaagacg aaaacgaagt cgtggaacac acccaagcac
     2881 aaaagttaag tagtcaaata ttagcaaaac tagccaccat ctatccaatt gaattttctc
     2941 ctgatgaaat caattatctg gctttgcgta tcgccaatct ttttacaaat tcacaagcag
     3001 ccacacgttt tcaaaaggaa tctagcgcac ttgctgatca tttgatcgaa caagtggaac
     3061 agtttctagg ctattcatta aaagaagatc agctactaaa acaaaattta aggtctcatt
     3121 tatcttcaac ttattttcga ctccattatg gtttgcagat ttctaatcca ttgacgaaaa
     3181 atgtgtttag tacgtacaca caacttttct tagttttaca gttaatttta gaagattatt
     3241 ttgaaaagga aaatttttat gttccacaag aggagacagc ttatttaacg atccatttcc
     3301 aagcagcgat cgagcgacac aaacatcaga aaagtagaag atatcaaacg gttttagtta
     3361 gtgaatattc aaaagctatg gctacttttc tcgaagcacg gctgaacaga gaacttccag
     3421 aattaacgat tatggatcta gttgaatata agccagaatt aaagagacaa gattttccct
     3481 ctgttgattt tatcttggct acgttaccat ttaaacatat aagcattcca gtaatcgaga
     3541 tctcaccaat gatcacagaa actgatctag cctatttgac aaaatatatg ctggagcatg
     3601 tgcctatcaa gaagaaaaaa acatttgatc tagcaagctt tactcatcca tttctgatct
     3661 ttcctcaact tgaacggaca gacccagccg atattttaaa ctttatggga aacgtcttag
     3721 tggaacatca ttatgtggag ccggaattca tcgattctgt cttggaaaga gacagtcact
     3781 ccagtactag agtagcacca tttgtaacaa tccctcacgg taatccgctg tatgtgaagc
     3841 attcgatgat ttctattgct acaatgaaag aaccagtcct atggcacggg gaacagatac
     3901 gtatcgtact gctattagca ataaagaaaa atgatttgaa acatgcagag ttcaaaaaaa
     3961 tattttctgt tattcactat ctagaaaagc agccagaaca aatggctcag ttgatgcaat
     4021 ccaatcatcc gctagaaatc ttaacgttgt tatctagtta tgaataagta gcgattaaaa
     4081 aactgccttt atatttataa taattctatc tatttatttg gaagtagaaa actaaataca
     4141 aaaaaagagg atgtggccaa agttgtggca catcctttta ttttgagttt cttataattt
     4201 tttatagttg cttacgatgt cttgactact ggtaaacggt gttcaagaga caatttgtcg
     4261 gcaataaggc acaattttgt aaaatatgga aagctatttt tttaacattg tttcttagtg
     4321 cttgaaaaat cattttgaat acttctttat acgatcgatg tacgttgatt taagtctaaa
     4381 acttttcttt tgattccttc tctgactttt ctgaattccg ttaatatttc ttcttcgctc
     4441 ccgacagctt gtgcaggatc ttttaggtcc cagtgaaggt gttcgtgatt gtttggaacg
     4501 gcagggcact tgtctttggc atcaccacaa agtgtaatga tcaagtctgc ctgagtaaag
     4561 taatctcta
//
LOCUS       DAFLVO010000135         4559 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.140, whole genome shotgun sequence.
ACCESSION   DAFLVO010000135 DAFLVO010000000
VERSION     DAFLVO010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4559
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.140"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(15..356)
                     /locus_tag="L1U99_002818"
     CDS             complement(15..356)
                     /locus_tag="L1U99_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBN1213318.1"
                     /translation="MKPNEIVTVYVAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     NKSDQIKRVYFPIAEWEKVGLKKQSWIDVGSLKAIPKSRENISFKKVGMLSAIDTKKL
                     NRFIERLQRKV"
     gene            complement(346..627)
                     /locus_tag="L1U99_002819"
     CDS             complement(346..627)
                     /locus_tag="L1U99_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBN1213319.1"
                     /translation="MKVKNPKEKSRIQVGIDKDLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTMDMPVDVLDTDEKLEEWFNEA"
     gene            complement(734..1318)
                     /locus_tag="L1U99_002820"
     CDS             complement(734..1318)
                     /locus_tag="L1U99_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213320.1"
                     /translation="MNENKMVLSEYARLRTINWLNGMQSSGAFDGFDEENMDFESLSN
                     EDIRYYFIEWYFTEPDEEVEDEPELILERQRILFSEQDSKRLYGLYDLQLKGLKAQYV
                     ADSYDDMVEQGADRVVTYSEDDEEEWENYSDDEICFNDGYMPIEITEEEYDKVSDSDE
                     IGMCTVVSGLDIDVQRVEVAYQKMKERIKSKVES"
     gene            complement(1335..1574)
                     /locus_tag="L1U99_002821"
     CDS             complement(1335..1574)
                     /locus_tag="L1U99_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213321.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEELLRKAKQKGYPDKMLKQIGYYM
                     SEERIEKESCKVLFDSEQLLVLLTQNKLICQFENN"
     gene            complement(1593..1841)
                     /locus_tag="L1U99_002822"
     CDS             complement(1593..1841)
                     /locus_tag="L1U99_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213322.1"
                     /translation="MEGMDFIDHEDLIDFGYTWKGMVGISRSLANAFYERNYAVYVLY
                     DDNTESLVDEEYKLDLENVLYGIEKEDLAKYIFSWLGQ"
     gene            complement(1856..2422)
                     /locus_tag="L1U99_002823"
     CDS             complement(1856..2422)
                     /locus_tag="L1U99_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213323.1"
                     /translation="MFEKRKDQFPNLEAKSQKVIDGEMIELFQKSYGTIETTASCKYY
                     FQGKRNTFKGFADSDEELAKKIIDWLVSSEHVAREDTVRTTIEGEVLTGTRCVCCNHE
                     FVEDEGCYRINEYGDFICQSCHEIEFPTERSWFEYMLQDYEMETENGEVVFCTKEELS
                     KRSDDEIEDWCVWLVGTDDCVAYYTTAE"
     gene            complement(2423..2968)
                     /locus_tag="L1U99_002824"
     CDS             complement(2423..2968)
                     /locus_tag="L1U99_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213324.1"
                     /translation="MGERTQALITVKYGNSKTKVSVSIHYQWGYGRFMLMDVLNQGIY
                     LINKAYDLRDESREELAKGIFDRSTGVINFVTYESGVSAYDETGFGGRYEPYQETIED
                     VMKFSDNNDGYAHLEMVFDENGFSLDDKTRLRLFDFEGQQIGLNKFCESGKEFATKDF
                     IKGYRLLLENYGINLEEESVK"
     gene            complement(2994..3761)
                     /locus_tag="L1U99_002825"
     CDS             complement(2994..3761)
                     /locus_tag="L1U99_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HBN1213325.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIKEKYLNEWNSTYEMVMTDNFEKVLDFRNALLGSDMGNSSLESIEVEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGYEFPSENDKSF
                     TTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQENGSL"
BASE COUNT         1274 a          991 c          599 g         1695 t
ORIGIN      
        1 aaagaaaagc cttgttagac ttttctttgt aatctctcga taaacctatt tagctttttc
       61 gtatcaatag ctgatagcat accaaccttt ttaaatgata tgttctctcg gcttttggga
      121 atagccttta aagaccctac gtcaatccat gattgcttct ttagacctac tttttcccat
      181 tctgcaatag gaaaatacac tctctttatt tggtctgatt tattctcata ttgacttgtg
      241 attccaaaaa attctactct atcttcttta tcactaacca ccaaaatagg tcttctttta
      301 ccaccatttt tatctgtaaa tgcaacatag accgttacta tctcattagg cttcattgaa
      361 ccactcttct aacttttcat ctgtatctag aacatcaact ggcatatcca tagttagctg
      421 ttgcaatctg attccttgct tttcctcttc gcttagcttt atctctactg gaaactcacc
      481 tctagcgacc acttgcttat aaaggattgt gattgctgtt gttggattta accctagctc
      541 ttccaatatc atttctgcgt tttcttttaa atccttgtct attccgactt gaattctgct
      601 tttttctttt ggatttttta ccttcatttc gttcacctct tttgagtata atatactcat
      661 tattatatcc attaactaca tttatgatta tattatactc ttaattagct actttgcaaa
      721 caatccaatc aaatcaagat tctactttac tttttatacg ttctttcatc ttctggtatg
      781 caacctctac tctttggaca tctatatcca atccacttac aaccgtacac ataccaatct
      841 catcgctatc cgacacttta tcatattctt cttcggtgat ttcaataggc atatacccat
      901 cattaaagca tatctcatca tctgaatagt tttcccattc ctcttcatca tcttctgaat
      961 aagtgacaac cctatctgcc ccctgttcta ccatatcatc gtaactatca gcaacatact
     1021 gcgcttttaa tcctttcagt tgtaagtcat ataaaccata caacctctta ctatcttgtt
     1081 cactgaataa aattctttga cgttctaaaa ttaattctgg ttcatcttcc acctcttcat
     1141 ctggttctgt aaaataccat tcgataaaat aatatctaat atcctcattc gataaacttt
     1201 caaagtccat attctcctca tcaaatccat caaaagcgcc actactttgc ataccattca
     1261 accaattaat ggttctcaat cttgcgtatt cacttaatac catcttattc tcattcatgg
     1321 ttcttcaccc catattaatt attttcaaat tgacaaatca atttattttg agttaacaaa
     1381 actaatagct gttcactatc aaaaagaacc ttacaagatt ctttttctat tctctcttct
     1441 gacatgtaat agccaatctg ttttaacatc ttatctggat aacctttttg tttggctttt
     1501 ctcaaaagct cttcatcatt cccaacataa taataagaac accattgcat acctttactt
     1561 ttgaattttg tcatgttgct accctctttc gtttattgac ccaaccatga aaaaatatat
     1621 tttgctaaat cttctttttc tatcccatat aaaacattct ctaaatccaa tttatactct
     1681 tcatcaacaa ggctttctgt attgtcatca taaaggacat agactgcata atttctttcg
     1741 taaaaggcat tagcaagact tctgctaata cctaccattc ctttccatgt ataaccaaaa
     1801 tcaatcaaat cttcatgatc tataaaatcc attccttcca tgctgattca cactcctatt
     1861 ctgctgttgt gtaatatgca acgcaatcat ctgtccctac taaccacaca caccaatctt
     1921 caatttcatc atcgcttctc ttactcaatt cctctttggt acaaaaaact acttcaccat
     1981 tttctgtttc catctcataa tcttgtagca tgtattcaaa ccaacttctt tcggttggaa
     2041 attctatctc gtggcaactc tggcaaataa aatcaccata ttcattgatt cggtagcaac
     2101 cttcatcttc tacaaattca tgattacaac aaacacatct agtacctgtt aggacttcac
     2161 cctcaatcgt tgttctaacg gtatcttctc ttgctacgtg ttcactgctg acaagccaat
     2221 caatgatttt ctttgccaat tcttcatcag aatcggcaaa gcctttaaac gtgtttctct
     2281 ttccttgaaa gtagtatttg caacttgcgg tagtttctat ggttccataa cttttttgga
     2341 ataattcaat catttcacca tcaatcactt tttgactttt cgcttctaaa ttagggaact
     2401 ggtcttttct tttttcaaac acttatttca cgctctcttc ttctaggttt attccataat
     2461 tttctagcaa taatctgtat cccttaataa aatctttcgt agcaaactct tttccgcttt
     2521 cacaaaactt gtttagtcct atctgttgac cctcaaaatc aaacaatcgc aatctggttt
     2581 tatcatctag actaaatcca ttttcatcga acaccatctc taaatgagca tagccatcat
     2641 tgttatctga aaacttcatc acatcttcaa tcgtttcttg ataaggttca tagcgcccac
     2701 caaaccctgt ttcatcataa gcactcactc cagattcata ggtgacaaaa ttgataactc
     2761 ctgtacttct atcaaagatt ccttttgcta attcttctct tgattcatct cgtaagtcat
     2821 atgctttatt gattaaatat attccttgat tcaaaacgtc catcaacatg aatcgaccat
     2881 atccccactg ataatgaatt gacacgctta ctttcgtttt gctgttacca tatttgactg
     2941 taattaacgc ttgtgttctt tcgcccatct tgttttcctc ttttctctaa tttttataaa
     3001 gaaccatttt cttgaaatga gtaatagctt gtgtttttac ttgttacgat gatatggtct
     3061 aacaattcaa taccaattgt ttttcctgcg tttttcaaat tcgtagtaaa acttttgtca
     3121 ttttcacttg gaaattcata tccgctcgga tgattatgtg atactgcgat ttttgctgaa
     3181 ttgtttagca aagctagttg aaaaatctct cttggtatcg ctactgattg attaattcca
     3241 cctttgaaaa cttcgctata agcaatgacc tcattctttg tattcagaca catcactagc
     3301 aaagattcac tagcattgtt tccaattaag ttagtagcaa agtttgctag accaaccgag
     3361 cttgtgactc tataaaaact tctatcttca ctgatatatt tttgttcgat tttcaggaca
     3421 ttcttaatca atccttcacc ttcattctcg gtcttgtttt caacttcaat agattcaaga
     3481 ctgctatttc ccatatcaga acccaacaaa gcatttctga aatccaatac cttttcaaag
     3541 ttatcagtca taaccatttc ataggtgcta ttccattcat tcaaatattt ctctttgatg
     3601 agaatgaacg ctctcggttt acttctgcca attctgatat tttgtgtatc gtgaaaaata
     3661 taattatcaa gtaaagtacc atcgtacttt tcatagttcc cactgatatt tgttaacttg
     3721 tttaccattt cttgattaac ttctaaaatt ctatctctca tgttgaacgc ttctttctgt
     3781 ttttgatttt tggtttttca aaattctttt ttgtttggat tgttttagag ggaggtggtt
     3841 ttttcttcat cgctatttgg ttttgcattt tatgtttctt cctttcgttc atttatttat
     3901 ctttttcgcc tgtcttgcct tgtcgggagt gattagaatg cgttcttatc tgccggatta
     3961 atacaagtgt ttaagtaaat tattttcgta acgcttgcgt ttagaaaaaa atttacgcca
     4021 cttgtattaa tccaaagatg agataagctc taaacacttc tgacaaggta tgacaggcga
     4081 aaaagataat gggcgtaagg aattataaat ggcaaaacca aataaagagc gatgaatttc
     4141 aatgctttca ggcgtagctt gaaagcctaa aagtcttgaa gaatgaaaga ctttttacct
     4201 tcaaagcaga cctagtaatc ttaaataggc gatggctatt taagattacg gtgttgaccc
     4261 actaaataaa cagaaatgga accgatcaag caaaatcgga ctaggcacta ggcgatggct
     4321 aggacggttt gcggtggctt taggaaacgt tcatggtgag atgagcatat ctagcaatgt
     4381 cgggctaagc tatgcttaga acggcttgcg gtggctttag aaaactttta tggagagatg
     4441 cactaatcta gcgatgtcgg actaggcaat ggctaggacg gcttgcggtg gctttagaaa
     4501 acttttttgg agagatgcac taatctagcg atgtcggact gggcaatggc taggacggc
//
LOCUS       DAFLVO010000136         4433 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.141, whole genome shotgun sequence.
ACCESSION   DAFLVO010000136 DAFLVO010000000
VERSION     DAFLVO010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.141"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(543..2048)
                     /locus_tag="L1U99_002826"
     CDS             complement(543..2048)
                     /locus_tag="L1U99_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1213326.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDPFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="L1U99_002827"
     CDS             complement(2045..2731)
                     /locus_tag="L1U99_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1213327.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="L1U99_002828"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="L1U99_002828"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HBN1213328.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1238 a          919 c          730 g         1546 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa agggatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat att
//
LOCUS       DAFLVO010000137         4418 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.142, whole genome shotgun sequence.
ACCESSION   DAFLVO010000137 DAFLVO010000000
VERSION     DAFLVO010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4418
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.142"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            61..915
                     /locus_tag="L1U99_002829"
     CDS             61..915
                     /locus_tag="L1U99_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBN1213329.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1012..3261
                     /locus_tag="L1U99_002830"
     CDS             1012..3261
                     /locus_tag="L1U99_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBN1213330.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3264..>4418
                     /locus_tag="L1U99_002831"
     CDS             3264..>4418
                     /locus_tag="L1U99_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1213331.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1557 a          625 c          806 g         1430 t
ORIGIN      
        1 atgtaataat ataaacataa taaaacaaaa attatccaaa tctaacatag gagggtggat
       61 atggaaaatt ctatatattt agtaacagaa cctaacactc agctgaaaga ttgttacttt
      121 aatttttgtg ggtattcaaa aacagaacct agacatagtt ttggaccagc tattcgagaa
      181 caatacttaa tacacatagt gctagaaggt gaaggctatt attcaattaa tgatcaaaaa
      241 tattttctga agaaaggcca aggatttgtt atcccaccag gagtatctac tttttatcaa
      301 gcagatgaaa aaaatccgtg gtcatatgta tggttgggtt taagtggcaa tcttgtagaa
      361 tactatctaa aagaaattgg tgttggaaag aatcatctta cctttaaagt cgaaaattta
      421 aattcattta aaggattaat ttttgaaact ttatcgtatg atcaggacaa tctagtcagt
      481 gaattgtcca gacaaaaaca agtttataaa tttttagaac tcctcttaaa ttcagctagt
      541 tatctgaacg aagggataat tactaaaaag atgaatcctt ttgttcgtca aacaattgaa
      601 ataatacgtg agaatgcgta tcaaaaatta tctgttaaag atattgctgt cagtctatcg
      661 atacacgaaa attatttatc acgattgttt aagaatgata tgggaatatc aataaaagag
      721 tatattagtg aaatcaaaat ttctattgca aacgatctgt tatcatcaac tgaatattca
      781 atccagcaaa tcagtgacaa gataggattc tcaacagtac aatctttttc taaagccttt
      841 aagaaagcaa atggtgtttc accgggagta tatcgaaaac gtagattagg tctaggaatc
      901 attaatggtg aataaactaa acatttgatt ttgataaata ttcgttactt taaacgctta
      961 ctatttatgt gagcgttttt tataatgcaa taaagaaacg gaggagagct tatgtataag
     1021 gataatgaaa tgaatattat ttatcgatca gaaaaccaac aatttcattt gtttaatcag
     1081 gagataagtt acatttttaa gatatcggaa gatggtaaat tattgcattt atattatggt
     1141 gagaacttac cagataatga ctatagtcat ctaattgaga tgcatcatcg gcctatgaca
     1201 acctatagaa atgaaaacga tttgctatat tcgttagagc acttaaaaca agaatttcct
     1261 gaatatggta caacagattt tagacatcct gctatttcat tactacagaa aaatggctct
     1321 cgcttatcag attttgtcta tcaagggtac gaagtggaag aaggaaaacc taaactagaa
     1381 ggtttacctg ctacctatgt tgataataat gatgaaagca aaacattgaa agtttatatt
     1441 ttagattcag ttacaaatgt tcaagtagaa ttattatata caatttatag agattatcct
     1501 gttattactc gtagcgcgcg agttatgaat aaaggaaaag atattcaaat aatcgagaat
     1561 attagcagtt tatcattgga tttacccgat gcaaattatg aatggcaaca attatctggt
     1621 gcttggggta gagaaagaac tattaagtcg cgtactttac aacaaggaat tcaatcaatc
     1681 gaatctactc gaggtatttc aagccatcag cataacccat ttgttacttt aaaaagaaaa
     1741 aatactgatg aaaatcaagg agaagctatt ggtgcagcac tagtttactc aggaaacttc
     1801 ttaattcaag cagaagtaga tacatgggat gttactagac tacaagttgg catcaatcca
     1861 tttggattta attggaaact caatccagga gaaatattta cagcaccaga agcgattctg
     1921 gtttattcaa gtaagggttt aaatgccatg agtcaaactt ttcatcaact atttagaaaa
     1981 cgcttagctc gtggtaagtg gcgagaaaaa gaccgtcctg tcttaattaa taattgggaa
     2041 gcaacatatt ttgattttga cgaagaaaag ttggtaaata ttgctaaaaa agcatttgat
     2101 gttggtattg aattatttgt attagatgat ggctggtttg gagaaagaga aaacgattgt
     2161 gcaggattag gagattggca tgtaaatcct aaaagactac ctagaggaat cggcagcctt
     2221 tcagaaaaaa ttcgtagttt tggtatgaaa tttggtttat ggtttgaacc tgaaatggtg
     2281 aataaggata gtgagttata tcgcacacat ccgaattgga ttatttctac acctaatcga
     2341 aaacctaatc atggtaggaa ccaatatgta ttaaattttg ggttagatga ggttgttgaa
     2401 aatattttcg atcaaatgtg taaaatcatt gatgaatcaa acttagatta cattaagtgg
     2461 gatatgaatc gtccattgac tgatgtattt gacagtcact tgtcagcaga tcaacaagga
     2521 gaagtattcc acagatatgt actaggcgta tatcgcttat atgaaaaact tataacaaaa
     2581 tatcctaaca tactatttga gtcttgttca tcaggtggtg ggcgctttga tcctggaatg
     2641 cttcactatg cacctcaagc ttgggctagt gatgattcag atgcaattga aaggttaaaa
     2701 attcaatatg gaactagtat gctgtatcct ctttcgtcta ttggtgctca tgtatcaatt
     2761 gttccaaatc atcaaacaaa ccgtataaca cctataaaaa ctagaggaaa tgtagctttt
     2821 tttggtgcat ttggatatga gcttgactta aatgaattaa gtgaaggcga tttgaggatt
     2881 gtaaaagaac aaattgcctt ttataaaaaa tatagaacca taattcataa tggtactttt
     2941 tatagactat tatcaccatt cgatgatgat aatcaaaccg cgtggatggt tgttagtcat
     3001 gataagaaaa cggctattgt tgctcattat aaaacattaa atgaggtaaa tgctccttac
     3061 cgccgactga aattaaaagg gttagataat gacggacttt ataatgtagg acaaaatagt
     3121 ttgcgatctg gaatggaatt gatgagagca ggactagtct gttcagatgc atctagtgga
     3181 caaataaatg atcagaatcg acgcccagaa acatttgatt ttgattccaa gatttgggtt
     3241 ataacacagg aggaaaagta gagatgaata accaaaaaag cttacttcaa aaaggagcaa
     3301 tcttaagtat ttcactaatg ttaacaagct ctcaagcaat taatggtgtt attccacaaa
     3361 tgaaacagtc tttggggata tcacaaagtc aaagtgaact tttaggaact gcaccaagta
     3421 taactgttat tttgtttatc ttattatcta gttactttgc caaaagaata ggaatgaaaa
     3481 agacaataat tttaggttta ttattagctg gtataggagg aattattcca gtatttacag
     3541 ctaccttcca aaccgttctt attagtcgag taatattagg tgccggttta ggagtatata
     3601 attcattggc tgtgacatat atcagctctt tatactctgg caatactaga gcaacgctat
     3661 taggtattag aaattcaatg gaagctttag gtcagacaat ccttattttt cttgctggag
     3721 ttttagtgaa cattaattgg acggcttcgt ttttagtcta tgcaattgcg tttcctgtag
     3781 ctctcttatt cgcgctaaaa gttcctgaaa ttagagatga aaatagtgac atacctgaaa
     3841 atcatgtaaa agaaaagatg aatccaatgg tttttgccct agttctattt gcaatcttac
     3901 tcgtaatgaa tagtattgct atttctgtac gatttgcatc aattgcaact gaaattaaag
     3961 gggtaaactt taatgctagt aactatttag ctctaatgcc tatcttagga atactagcag
     4021 gatttatgtt tggaccaata aataagtgga taggaaaagg aaccctatac ttgggaatta
     4081 tattctttat aatttcaaat ttgttaattg ctgtgtcaaa cggtaatatg acgttcctgc
     4141 taacgggttt atttttatca agtataacag gatcatggtg cttcccattt atctttagta
     4201 acttagataa agtcactaca aagaatacaa ttaattttgc tacttcattg atttttattg
     4261 gctgtaatat tggtaatttt atagctccta ttgctatgca attagcacaa tttctaacaa
     4321 gaagtacaaa tttgactgct ccattttttg tattcgcagg aatatttatt gtgatcctat
     4381 ttgtaacatt ttttgcgaca aataaaaaaa atactaga
//
LOCUS       DAFLVO010000138         4374 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.143, whole genome shotgun sequence.
ACCESSION   DAFLVO010000138 DAFLVO010000000
VERSION     DAFLVO010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4374
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.143"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(83..1051)
                     /locus_tag="L1U99_002832"
     CDS             complement(83..1051)
                     /locus_tag="L1U99_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBN1213332.1"
                     /translation="MSKNGIIVNEWENLTALSNRRLNVQNMYTPLKMQWSIDRITIVG
                     KLKENIYYHTQNDVLILDFEQLMRVNEGNGYLKAVGNNGWQLLDQYEENIAYIEILKW
                     QDGKGRIDFNPNKIGHFLASSMKNFIHDLFLEPHFSRADIACDIIDVPDEFITQYRVV
                     DPVSFKPIYGRSGKLETAYWGSRASERQIRLYNKKLEQETKRKIVPPEIETWWRLELQ
                     LRRGKATDWHAMVHESLNSFASPHFLPLDVKTNDKVMIFGLIANPEMWGFLERRMKYK
                     LRDILKRESQNDELTNHLRETFSESADVLKKELDTWLQGLDVTEEE"
     gene            complement(1498..2904)
                     /locus_tag="L1U99_002833"
     CDS             complement(1498..2904)
                     /locus_tag="L1U99_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HBN1213333.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDRQKTNDWHKHIDFTKSDEN
                     IYLEQTNLADKYEELFGEVVEKYNAKQKRADRKIEDYLAKVRKDKKLEPQREFIVQIG
                     ILDDFQTNRADGSYTGISKQQAEQNRVIANKILVQYYKEFQERNPNLAVYNAVIHNDE
                     ISPHLHLNIVPVAEGYKRGVQKQPSFNKALVQQGIHADKDNGRVLFNNFRNQEVDSIE
                     RLMNDYGWKRDIVGTNKIKDIHEYKEIMSEISELRQTAVKERESVSDELRYIYRQREE
                     NERDKALMASERAKIEEEKKNMLNVKKEMAVIFQKDMVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVATLEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQRKLERSEDEIEW"
     gene            complement(3126..3488)
                     /locus_tag="L1U99_002834"
     CDS             complement(3126..3488)
                     /locus_tag="L1U99_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213334.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFETFADFERWLSSISDDQQHEKSVDNEWLADEKSAPSERDYPDESDGLFGVIPNKK
                     SQMSESKFTSIFNDVNLR"
     gene            complement(3492..3830)
                     /locus_tag="L1U99_002835"
     CDS             complement(3492..3830)
                     /locus_tag="L1U99_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213335.1"
                     /translation="MVAILEVRCDMDKIDLREETVDRIELMYERLADYLNLPDEDNYS
                     EMLERMMDVLNSVINADLAKSSVLTNEFVHKHLAQTTDESEKEFWLKLMSHVMQLNQI
                     SVINSKEKEM"
     gene            complement(3809..4228)
                     /locus_tag="L1U99_002836"
     CDS             complement(3809..4228)
                     /locus_tag="L1U99_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213336.1"
                     /translation="MTDLPEKMTIKNLADELGISKNTVRNQLVNAGYDLARYKDNGVI
                     MLDKELIGVVRSIYRSKGGQLTGDLPVNDAGNDFPLEKENEFLREQLAEKDRHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            complement(4221..4361)
                     /locus_tag="L1U99_002837"
     CDS             complement(4221..4361)
                     /locus_tag="L1U99_002837"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213337.1"
                     /translation="MSGKLLDVTQYELILKNNKIDSPIIIPKHAVKYVYGVAESNGED
                     ND"
BASE COUNT         1234 a          995 c          617 g         1528 t
ORIGIN      
        1 aaaaaaacaa cgacaacgtt atcacctgtt aaattcacca accaattttt cttaccaaaa
       61 tgcttttgtt tttctgccat tcttattcct cctccgttac atctaaccct tgaagccaag
      121 tgtctaattc ttttttcaaa acatctgctg attccgaaaa tgtttctcgt aaatgattcg
      181 tcaactcatc attttgactt tctcttttca aaatatctct caatttgtat ttcattctac
      241 gctctaaaaa cccccacatt tcagggttag caatcagtcc aaaaatcatc accttatcat
      301 ttgtttttac atcaagtggt agaaaatgag ggctagcaaa actatttaaa ctttcatgaa
      361 ccattgcatg ccaatctgtt gctttcccac gccttaactg caattccagt cgccaccaag
      421 tttctatttc tggtggcaca attttacgct tggtttcctg ttccaatttt ttgttgtata
      481 gccgaatctg gcgttcgctg gcacgactgc cccaataagc tgtttccagc ttcccagacc
      541 gcccataaat tggcttgaaa gaaacaggat caaccactcg atattgtgta ataaactcat
      601 caggcacatc gataatatcg caagcaatat ccgcacgtga gaaatgtggt tctagaaata
      661 aatcatgaat gaaatttttc attgaactag ctaaaaaatg accaatctta ttcgggttaa
      721 aatcaatccg ccctttgcca tcttgccatt tcaaaatctc aatataagca atattttctt
      781 cgtattggtc taataattgc cagccgttat tcccaaccgc ttttaaatag ccattgcctt
      841 cattcacccg cattaattgc tcaaaatcta aaatcaacac atcattttga gtgtgataat
      901 aaatattttc cttcagtttt ccaacgatag taattcggtc aattgaccac tgcattttta
      961 agggggtgta catattttgt acatttaacc gcctgttaga tagggctgtt aaattttccc
     1021 actcatttac gattatgcca tttttactca aattttgttc ctcctcaaag aaaaagagac
     1081 ttctggaaag aattttcaaa agttcacgta actcttaaaa attcattacc aaaaaatctc
     1141 tagtcttgaa gaaatctaaa aatattcgta taatgattaa gaagttacgg agctagtgcg
     1201 attagtttcc gtaaaggtcg agaacgttgg tagcgttgct cgactatttt tttactcttt
     1261 tttcagttca tttgtttgct aactcaataa tagcacttct ctttagctat gcaaatatcc
     1321 aaaaaataaa accgcaccct ttgaaaaggg cgcccccaaa cttcgctaac gctaggttgg
     1381 ccaaaaaatg gactggccat tttttagcaa atgtcagctt aataggctag tggtttagcc
     1441 gtcaactcct tatcctcggc acaaaccgcc tccggtaccg ttgactgcac atcgtaacta
     1501 ccactcgatc tcatcttcag aacgctctaa tttacgctgt gagacgtttt gacgataaaa
     1561 taaggttttc tcctgctcta acacttctaa ttcctcagaa agccccatat ccttttctgc
     1621 aagaccaaaa cggatagaca aacgagtgat cgatttttga aatgcgtttt ttaatcgctc
     1681 taaacgctgg cgtaaagagc gattttcttc tttcagcttt ttattttcca cttgtaaatc
     1741 tgctaattgt tttctaccag acaaatgacg ctcttcttcc aatgtagcta catactcatt
     1801 taattctgta ttttgctcaa gcatctgtaa atattgctca ctcatgttat cagcatttct
     1861 cttggcattt gttgctctcg tagctcgttg atacaaatca acaaaatcat tcccagataa
     1921 atgatacgaa ccatcaggaa gcctcttgaa actttctaaa ggaaccatat ctttttggaa
     1981 aatgaccgcc atctcttttt ttacattcag catatttttc ttctcttctt caatcttcgc
     2041 tctctcagaa gccatcagag ccttatcacg ctcgttttct tctctttgcc tataaatata
     2101 cctcaactca tcagaaacgc tctcacgctc ttttacagcc gtttggcgca attcagaaat
     2161 ttcactcatg atttctttgt attcgtgaat atctttaatt ttgttggtac cgacaatatc
     2221 ccttttccaa ccgtaatcat tcattaatcg ttctatagag tcaacttctt gatttctaaa
     2281 attattgaaa agcactcgac cattatcttt atcagcgtgt atcccttgtt gaaccagtgc
     2341 tttattaaag ctcggctgct tttgaacacc ccgtttataa ccttcagcaa ccggcacaat
     2401 attcaagtgc aggtgcggac ttatttcgtc attatgaata acagcattat aaacagccaa
     2461 attagggttt ctctcttgaa actccttgta atactgaacc aaaattttat tggcaatcac
     2521 tcgattttgt tcagcttgtt gtttcgatat gccagtataa gaaccatctg ctcgatttgt
     2581 ctggaaatca tctaaaatgc ctatttgcac aataaattct cgttgaggtt ccaacttttt
     2641 atccttgcgc actttcgcta aatagtcctc gatttttcta tcggctcttt tttgtttcgc
     2701 attatatttt tctaccactt cgccaaacaa ttcctcatat ttatctgcta gattcgtctg
     2761 ctctaaataa atattttcat ccgatttcgt gaagtcaata tgcttatgcc aatcattggt
     2821 tttctggcga tcagttaact cacgattatt atgagaaata cttgtattct tcgttccttt
     2881 tttaaatgaa atactaaacc ccaagttaaa accctccttc gcgctgtcgc taataaaaag
     2941 attgtaaacc tttctgttac tctttgtcaa agagtaacat tttcctaatt gtgacatggc
     3001 tgtcacaatt ccaaatgctc tccgagggta ttcgctgtca caagtgacaa cgaaaaaagg
     3061 agccgaaagc gtgtcacgct ctcaactcct tttacgcttt attttgcttc acgcaaaata
     3121 atcgcttatc gtaaattcac gtcattaaat attgacgtaa atttactctc actcatctga
     3181 cttttcttat tcggtatcac tccgaataag ccgtcagatt catcgggata atctcgttcg
     3241 cttggcgctg atttttcatc agcaagccac tcattatcca ctgatttttc gtgttgctga
     3301 tcgtcagaaa tcgacgatag ccaccgctca aaatcagcaa aagtttcaaa cccaaaacgc
     3361 ttgcgaagag ccttgcccat tgcagcattt tctttctcaa tcaagcgttt tttctgttgg
     3421 cgaagtttcg cttgttcttt ttttaatttt tcttcttgcg ctttaatatc tgctaaagtc
     3481 attcccataa actacatctc cttttctttg gaattaataa cggaaatttg gtttaactgc
     3541 ataacatgac tcattaattt caaccaaaat tctttttctg attcatcagt tgtttgcgct
     3601 aaatgcttat gaacaaattc attagtcaaa actgaagatt ttgctagatc agcattgata
     3661 accgagttga gaacatccat cattcgttca agcatttcac tataattatc ttcatccggc
     3721 aaattcaaat aatcagctaa ccgttcatac atcaattcaa ttctatcgac tgtttcttct
     3781 ctcaaatcaa ttttatccat gtcacacctc acttccagaa ttgccaccat tttcgatttt
     3841 ttaattcttg attttctagt aacaactgat cgtttttttg ttgctgaagc aaagtcaatt
     3901 tttgttggtc acgaatcatt tccgttaatt cagaaatatg cctatctttt tccgctaatt
     3961 gttcacgcaa aaactcattt tctttttcta acgggaaatc attgcctgca tcattgaccg
     4021 gtaaatcacc agtcaattga ccaccttttg accgataaat tgaccgcaca acaccaatca
     4081 attccttgtc taacatgata accccattat ctttataccg agcaaggtca taacctgcat
     4141 tgaccagttg attgcgcact gtatttttag atatacccaa ctcatcagca aggtttttta
     4201 tggtcatttt ttctggcaaa tcagtcatta tcttctccgt tactttcagc taccccataa
     4261 acatatttaa cagcatgctt agggataatg attggggaat caattttatt atttttcaaa
     4321 atcaactcat actgcgttac atcaagtaac ttaccggaca tttttttgct atcc
//
LOCUS       DAFLVO010000139         4366 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.144, whole genome shotgun sequence.
ACCESSION   DAFLVO010000139 DAFLVO010000000
VERSION     DAFLVO010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4366
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.144"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            175..519
                     /locus_tag="L1U99_002838"
     CDS             175..519
                     /locus_tag="L1U99_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBN1213338.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            520..939
                     /locus_tag="L1U99_002839"
     CDS             520..939
                     /locus_tag="L1U99_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBN1213339.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVIFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1031..1381)
                     /locus_tag="L1U99_002840"
     CDS             complement(1031..1381)
                     /locus_tag="L1U99_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213340.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1347..2678)
                     /locus_tag="L1U99_002841"
     CDS             complement(1347..2678)
                     /locus_tag="L1U99_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HBN1213341.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2934..3500
                     /locus_tag="L1U99_002842"
     CDS             2934..3500
                     /locus_tag="L1U99_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1213342.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3645..3732
                     /locus_tag="L1U99_002843"
     tRNA            3645..3732
                     /locus_tag="L1U99_002843"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3677..3679,aa:Ser,seq:cga)
     gene            complement(3784..>4366)
                     /locus_tag="L1U99_002844"
     CDS             complement(3784..>4366)
                     /locus_tag="L1U99_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1213343.1"
                     /translation="FFSLLAFTGIRKGEAFALTWSDIDFKSKTLNINKTVTRGYQGRL
                     IVNTPKSKSGKRKIYLDNDLISLLRKYYTKNKTIVTIQRENLIFHHDGLLYNPTVSRS
                     WLNVIYKHHPELTKRITTHGFRHTHASLLFESGASLKDVQERLGHADIQTTSNIYTHV
                     TETQNKKVINNFVAFMKNSTQGESKGESKNILG"
BASE COUNT         1566 a          741 c          832 g         1227 t
ORIGIN      
        1 aaaataaaaa aagcgttagc aactatgctt aaaaagcata tcgactgaat aaactaagca
       61 ttggacaggc tgaaagacta catttaaaat gaaatgcgaa gaaacaatag aaaataaagt
      121 tgccttagaa ccatagttga atcacctaac agtcgtgaag ggagaataag agaaatggca
      181 gaaaaacaaa ccgcaggacg agatcaatta ggagattttg caccaaaatt tgcagaattg
      241 aatgatgatg ttttatttgg acaagtatgg tccagagaag aattatctgc tcatcagcgt
      301 agtatcatca ccatatctgc attaatttca ggaggaaatt ttgaacaatt gccagctcat
      361 ctgaagattg gcaagcaaaa tggcattact agtgaagaaa tagcagaaat cattacccat
      421 ttagcttttt atgtaggatg gccaaaagct tggtcagctt ttagtttagc aaaagaaatc
      481 tatttagaag aaaatagcga agataagaaa gaggcgtaaa tgacgacaaa acacgaagaa
      541 atacacaatg gcgtgatttt tccagcaggt gaaaaaaacg aagcttacgc tcaagtattt
      601 accgggcaaa gctatctgaa tatgttagtg aatgatcccg aagtttctgt tggtgtaggt
      661 aatgtaattt ttgaaccagg ttgtcgcaat cactggcatg tccataaaga cggctatcaa
      721 atcttacttg tgaccggagg agaaggctgg tatcaggaag aaggaaagcc agcaagacga
      781 ttaatggctg gagatgtcgt cgtaacgcac aaagggatta aacattggca tggtgcgaca
      841 aaagacagtt ggtttgaaca tttggcgatc actgctggta attcagagtt tttagaacct
      901 gtaacagatg aagtgtatga aggattggaa aatcaataat gtcaagcttg aacagctcct
      961 gaaagtagat tttaatcgaa ctttcaggag ctgctttttt gattcagtct tttataaata
     1021 gaaaataggg ttaataatag gaatgagaag cacgtcgaaa gatcttaata ttgataatcg
     1081 gctgggcata catgatttcc acgtcatcaa tcaaactacc taacagatga taatcttccc
     1141 gatcatgtcg gggattacct aatagttctt gatagtagat ttccatacta gggtcccgag
     1201 gattgttcag caaatcagca agtacatcta aatcttctgg ctgagtttct gccgtaccct
     1261 gtatctctat gaaaagccct tcctcagcaa attctactcc aatacgtatt tcagttattt
     1321 catgggaata taaataagta agaagctcat cgatgattct ttttgataat tctttttcca
     1381 agtgtctttt tttcctttct gacagcggta aagttatcta gtatcggtac aaggatacct
     1441 gcaacgaaac cagttgaaaa accactgtta tatagattta gtcctccgtg caaagtgctg
     1501 acgttatgga caagagcaat atgtagtaca ccagctatta caccgtaaaa actgccgtaa
     1561 aaaccgctta tgggcgcgag acctgtccca aacacagctg caacaagcat gccagtactg
     1621 gtgatctcat gaaaagttcc aaacaaagaa gcaataaata ttccgactag tatcggaaaa
     1681 ctgtttttta aatgacaacc aaaagcactg aaacccaccg cagataaaat agcaccgatg
     1741 acaggtccat ttaactgacc gccaaccagc aaaacataag aagacagcat cagaccaact
     1801 aagcctatgt tgatcaaagt agcaccaata ccagaattag caatgaaatc agttgtcaat
     1861 tttccagatg aatcgaaaat ttctcgaatc cccaaaagcc gaaaggaatt ataatagaaa
     1921 ccaattccga ctgtcagcga aaaaaagcca aaaataatcc aaatgagagg aaagtgatat
     1981 tcattgaaaa ccaatgtatt ttcgacgatt gaatagctga ataacctcaa aacagcagta
     2041 aaagtcatcg caatcaaccc agaggtgaat ccaatattat aaagtgtgaa tccacgatgg
     2101 aaaactaaag tttgagcagc taagggcgga agaagtagac caattgctat gccagctaaa
     2161 ttccccaata aaatacctat cagtaaagga aaacgcatac caaaagtgat ataactaacg
     2221 accggtgata atgcgctacc aaacagtccg atcatgatgt actgagaaaa aggtttattg
     2281 acaaatacag cgtatagata cacacctaaa atgattgaga tagaattata aaggtttttg
     2341 ccaaaaaaag agaaaccggt aactgttaga atcgaagcaa ataagggacc gtttaaaatc
     2401 accttgtgcc gataagctaa aagcacagaa agtaaggtca aaatccctac atttatgaat
     2461 gcgcttccga aaccgcctaa agcaaaataa tctgtcaaaa gattgcttgg cgaggtaaga
     2521 atagttagca atccactcca attatcagta ggagtattag aaagcaagcc aataaaaaga
     2581 aaaaaaacac ctgtaaaacc aagataaaaa tactttcttt tctgtgaaac gattcgtttt
     2641 tgaggatgaa tataaataac gtcagtttcg ttttccatta cacaccttct ttttcatttt
     2701 ctttaactat aacttgaaat gaaagatttg gacaactatc atttaggtca aaactaaaaa
     2761 tgtaagggaa cccattgaat ttaaccaaat ttttttaatt ttgcaaaaaa aagttaaaga
     2821 agactgaaaa aaaatttaaa atataacgtt ttgagtaaaa tgtttgcaaa aaatgctaaa
     2881 aatagggtac aataaaacaa catatactgc agtaaagaag tgggggagtt ttaatgagaa
     2941 gaaaagtcta taccaaggat caaattctaa aagctgctta tgatgttgtt gcaaaggaag
     3001 ggtttaaagg atttactgcg agaaatattg ctaaaaagat ggggatttcg acacagccga
     3061 tttatctgga attcaaaaac atggaagatt taaaaaatac gttgctggat tctatctttg
     3121 aacaactaaa agaagatgtt ttccctattg aacgtactgg tgataaaatc attgatctcg
     3181 gtttgaacta tatctacttt gcaaaaaagc atcatagtct ttacatggca ttgtacattg
     3241 atgaacatgg ggacggaaag aaaatgcatg atttttcata caattatttc cgtgaaatag
     3301 ttaaagaaga tgaaagatac aatcaattat cggatgaata tgtcgatgct ctgcatactg
     3361 gtacatgggt agcagtgact ggcttagcgt cattgatgtc atcaaacatc atgcatccaa
     3421 cagaagaaca aatcattgca ctgatcaaac ggacaattga ctcgatttta gcattagata
     3481 atcctgaaat aatcagatag tgttctatca gtatgaattt gatcggtaag tccgttggct
     3541 gcaaactgtc aatggacttt tttgctaaaa aaagcgattt ctgttattta tctattagaa
     3601 ataggcttga catttcgtga aaaaagttta aaaatagtac ttacggaagg ttggcagagt
     3661 ggtaatgcac cggactcgaa atccggcgaa ccggctaata ccggcgcgca ggttcaaatc
     3721 ctgtaccttc cttatatatc aacgattaga cacgatttcg atcgtgtctt ttttgttgta
     3781 tatttagcct aaaatgtttt ttgactcccc ttttgactcc ccctgagtac tgttcttcat
     3841 aaatgctaca aaattattga tgactttttt gttttgagtt tcagttacat gagtgtaaat
     3901 atttgaagta gtttgaatgt ctgcatgccc taaacgttcc tgaacatctt ttaaagaagc
     3961 tcctgattca aaaaggagag aggcatgagt atgtcgaaaa ccatgagtag tgattctttt
     4021 agtcaattct ggatgatgct tatatatgac attaagccac gaacgtgaaa ctgtagggtt
     4081 atagagaaga ccatcatggt gaaaaattaa gttttccctt tggattgtaa cgatcgtttt
     4141 gttttttgta taatactttc tcaataaact gatcaaatca ttgtccagat aaatttttct
     4201 ttttccagat tttgatttag gagtatttac gatcaatctt ccttgataac ctcttgttac
     4261 agttttattg atattgagtg ttttgctctt aaagtcaata tccgaccagg tcagagcaaa
     4321 agcttctcct tttcttatac ctgtaaaagc caatagggaa aagaat
//
LOCUS       DAFLVO010000140         4247 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.145, whole genome shotgun sequence.
ACCESSION   DAFLVO010000140 DAFLVO010000000
VERSION     DAFLVO010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.145"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            24..503
                     /locus_tag="L1U99_002845"
     CDS             24..503
                     /locus_tag="L1U99_002845"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213344.1"
                     /translation="MSRKIDNIILLTTIFYLVIGATLSLLSFLSNSSLIVLNQKSILT
                     EFAHIDYFSFFKTGLICLFLSSFILYIGTTFCLMVLNLKMFIIEKWIVIIAKIFSSIS
                     IIIPMTLTFSKEQFNVATTFVSFIALFSFAVPKTFQSKSSNAKVNVENTDRKNDESY"
     gene            complement(744..1010)
                     /locus_tag="L1U99_002846"
     CDS             complement(744..1010)
                     /locus_tag="L1U99_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213345.1"
                     /translation="MNILSEEFLTRLRIAIVEVVKDALSQLSKKNLSETRYLKKIEAR
                     KYVGGVNDQGFEKLIAHGLKEIRIDGFLRYDKKDIDELMAKYKI"
     gene            complement(1021..1212)
                     /locus_tag="L1U99_002847"
     CDS             complement(1021..1212)
                     /locus_tag="L1U99_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213346.1"
                     /translation="MSNLDNGRAAIKEFMKENGITMDDLATAYGHTRVRMQQILDGHW
                     SGPKANRTILEIIRDYRIR"
     gene            1503..1925
                     /locus_tag="L1U99_002848"
     CDS             1503..1925
                     /locus_tag="L1U99_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1213347.1"
                     /translation="MTTFERIKELAKNKNKNLQQVAKDLKYGENYFYSLNAGKQPTAE
                     KLQEIADYFDVSVDYLLGRTEKKRYYDLTEKDERDIQKELQSLIDDLSNADGMAFSKK
                     DNEMSEATREALIISLENALRIAKIEAKKKYTPKKYRD"
     gene            1942..2364
                     /locus_tag="L1U99_002849"
     CDS             1942..2364
                     /locus_tag="L1U99_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBN1213348.1"
                     /translation="MYLPQIDNKINKLVKLYQTRNPFRIARELKILVLEEDLGEIYGY
                     YSKFKQIKMIHINSSLDEMGKWITCSHELGHCVLHPNENTPMLSKKTLVSELKIEKEA
                     NYFATHLTIDPTLDGFDHMTKYEKLVCFGLPDEFDRFL"
     gene            2393..2593
                     /locus_tag="L1U99_002850"
     CDS             2393..2593
                     /locus_tag="L1U99_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213349.1"
                     /translation="MKIGMRKPSIKKSISARTTGKAKRKVKKAVIPGYGKKGSGWIKD
                     PKKAAYNKVYKKTTFSFWDLFK"
     gene            2680..3568
                     /locus_tag="L1U99_002851"
                     /pseudo
     CDS             2680..3568
                     /locus_tag="L1U99_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317363.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
     gene            3706..>4247
                     /locus_tag="L1U99_002852"
     CDS             3706..>4247
                     /locus_tag="L1U99_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
                     /protein_id="HBN1213350.1"
                     /translation="MAKKEIDKRIKKHLTKKGEEKYQFSLYLGVDPLTGKKRKTTRRG
                     FSTPLAAERALKRLEADIQEKGLQASTAQKSKKFEYVYGLWFENYKKTVKESTWSSTK
                     QIFDTHILKVFGDKFIDKIDVFFCQEAVNTWSDSHPKIFKKIKNYTSNVFDYAASLQI
                     ITSNPMKLVSIPRGEALDIE"
BASE COUNT         1561 a          722 c          696 g         1268 t
ORIGIN      
        1 tataattctg gtggggtgaa aacatgagca gaaaaattga taatataata ttgttaacaa
       61 ctatttttta tttagtaatc ggagcaactc tttccttact gtcatttttg tccaacagta
      121 gtttgattgt gttaaatcaa aaaagcatat taacagaatt tgcccacata gattacttct
      181 ctttttttaa aactggacta atatgtttat ttctatcttc atttatcctc tatataggaa
      241 ctacattttg tctaatggtg cttaatttaa aaatgtttat aattgaaaaa tggatagtta
      301 ttatcgcaaa gattttctca tcgatatcaa ttatcattcc aatgacattg acgttttcta
      361 aagagcaatt taacgtagct actacattcg tatcttttat agctctattt tcgtttgctg
      421 ttcctaaaac ttttcaaagc aaatctagca acgcaaaggt taatgtagaa aacactgata
      481 gaaaaaatga tgaaagttat taaaaaaaat aattctttca tttattgtca aacctttctt
      541 atagacatta gactttttta gtcagtccct cccgactggc tttttcgctc tgtactcagc
      601 ttcatcaagc ccaatgaaaa tccaaagcat gtaaacgatc gtgccgatta atgcttgtct
      661 actaccccat agacctaaag cgtagataat tagtggcgcg ctgaatacta atgttcgatt
      721 aaactttccc atgttgacct cctttaaatt ttgtatttag ccatcagttc atcgatgtcc
      781 tttttgtcat atcttaaaaa gccatctata cgaatttctt ttaaaccgtg agctattaac
      841 ttctcaaaac cttgatcgtt tacacctccc acatattttc tagcttcgat cttttttaaa
      901 tatcgtgttt ctgacaaatt cttttttgaa agttgactaa gtgcgtcctt tacaacttca
      961 acaattgcaa ttcttaaacg agtcaaaaac tcttcgctta gaatattcat gacttgcctc
     1021 ctatcgaatt ctgtaatcac ggatgatctc tagaatagtt ctgtttgcct ttggtccact
     1081 ccagtgtcca tcaagaattt gttgcattcg tacacgcgtg tgaccataag cagtagccaa
     1141 atcatccata gttattccat tctctttcat aaactctttg atcgccgcac gaccgttatc
     1201 caagtttgac attaacccac ttcctttttt tataaatttg taagttaaaa tgatagaaaa
     1261 aatataattt ccattgacat ttttacacta tagagtaaaa tgaatacata gagaaataag
     1321 cctataacaa aaccttttat ttgcacttgg tcgccaaact ttatgctata aggtgtgttt
     1381 ttagtttgct tttttctatc aaattaactt acggataaat aataactcta tatcgtaaaa
     1441 ttgtaaagct atttttactc tttttcgtaa attatttttt cgtgttggaa aggaacgttg
     1501 gaatgacaac atttgaaaga ataaaagaac tagcgaaaaa caagaataaa aaccttcaac
     1561 aagtcgctaa agatttgaag tacggagaga attactttta tagtttaaac gcaggaaaac
     1621 agccaactgc cgaaaagtta caagaaattg ctgactactt cgacgtatct gtagattatt
     1681 tgctaggacg tactgagaaa aaaagatact atgatttaac agaaaaagac gagcgtgata
     1741 tccaaaaaga attgcagtca ttaatcgacg atttatctaa tgctgatgga atggcttttt
     1801 cgaagaaaga taatgaaatg agtgaagcga cacgtgaagc tctcattatt tctttagaga
     1861 atgctttgcg aatagctaaa atagaagcta agaaaaaata cacacctaaa aaatatcgcg
     1921 attaaaagga gtacgttgtt tatgtattta cctcaaattg ataacaaaat taataagctg
     1981 gtaaaactat atcaaacacg caatcctttt agaattgcac gagaattgaa gatactagtt
     2041 ttagaagaag atttgggaga aatttatggt tactatagta aattcaaaca gataaaaatg
     2101 atccacataa attctagttt agatgagatg ggaaaatgga taacttgtag tcatgaatta
     2161 ggccactgtg ttttgcatcc gaatgaaaac acacctatgt tgtctaaaaa aacgctagta
     2221 tctgaattaa aaattgaaaa agaagcaaat tatttcgcaa ctcatctgac tattgatcca
     2281 actttagacg gctttgatca tatgacaaaa tatgaaaagc tcgtctgctt tggattacca
     2341 gatgaattcg atcgtttctt gtgaattata atacaacgta aggaggatat agatgaaaat
     2401 aggaatgaga aaaccaagta taaaaaaatc cataagcgct agaaccactg gaaaagcaaa
     2461 aagaaaagta aaaaaagcag ttattcctgg ttatgggaaa aaaggtagcg gctggattaa
     2521 agacccaaaa aaggctgctt acaataaagt atacaagaaa actacattca gtttttggga
     2581 tttatttaaa taaaaaaagc ccgtgcagca acacggactc gaaaccttat ttctaagatt
     2641 ccccaataaa aatcatatca tagaaatgag gaataaaaaa tgaaaaaagt aataacaagt
     2701 ttattagttt ttgcttctct gttacttttc actgcttgtg gtaaaaaagt aactacagaa
     2761 gatttaaaag ctaatgattg gttgattgaa gcaaccaaag atgacgaacc taatatgatc
     2821 gtatcatttt ctgatcacgt cgtatctttt agtgttgaca caagttctat gaaatcaact
     2881 tcaagtaacg attgggaggc tatgggagaa gaatttgcta aaagcttagt cgaccaaatg
     2941 aattacaaat ttgagtatac acttgaaggc gatgttatga cttggaaaga tgataaagac
     3001 aaagataatg atgccaaata tactgtcagc aaagaagata aaaatattat tttaactcca
     3061 gaaaagccta acaaatctga tgataatgag aaattagttt tgaaacccta caaaaaggaa
     3121 aaaaactaaa gaatctagaa caactactag ctcaacaagt agcaacgaac aatcatcttc
     3181 gactacaaca gaaagtacta ttgcatcttc tagtactgta gaacaagctg ctattgcgca
     3241 gaatacgcct cctgaaacta gtagtactta ctctgctgaa agtgtagaaa actatgcaga
     3301 agctactcct agttcaagtg ttgaacaagt ttcacccact cccagttcaa cggagcaatc
     3361 agtaccacaa gattatgtac cagctaatca agctcaacca acggcacctt cttcatctga
     3421 aaccgaaacc ttgactttgc aacctggtga agggaccaaa caaatagctg aacgagctgg
     3481 aattacggta gatcaactgt ttgcattaaa cggtatggat ccaaacaact acatgcttta
     3541 tccaggacaa gaactaagag tgaaataaaa aaagcacatt tgccgcccga ccaagaacgc
     3601 aaatgtgcaa agagctacgg taaagtaggt ctatttgttg taccctattt taccatctcg
     3661 aaatccgctg tacaaccgaa caaacgtacg aaaggaaaga taaagatggc aaaaaaagaa
     3721 attgataaac gaattaaaaa gcacttaaca aaaaaaggcg aagaaaaata tcagtttagt
     3781 ctgtacttag gagttgatcc tctaacagga aaaaaaagaa aaacaacgag acgaggtttt
     3841 agtacgccat tagccgctga gagagcttta aaaagattgg aggcagatat acaggaaaaa
     3901 ggactgcaag cttctacagc tcaaaagagc aagaaattcg aatatgttta cggcttatgg
     3961 tttgaaaatt ataaaaagac agttaaagaa agcacttggt cctccaccaa acaaattttt
     4021 gacacacaca tcttaaaagt gtttggagat aagttcattg acaaaataga cgtttttttc
     4081 tgtcaagaag cagtaaacac ttggtccgat agccatccta aaatttttaa gaaaataaaa
     4141 aattacacat ctaatgtttt tgattacgct gcttctttac aaattataac tagcaatcct
     4201 atgaaattag tttctattcc acgtggagaa gctctagata tcgaaga
//
LOCUS       DAFLVO010000141         4136 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.146, whole genome shotgun sequence.
ACCESSION   DAFLVO010000141 DAFLVO010000000
VERSION     DAFLVO010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.146"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            52..1353
                     /locus_tag="L1U99_002853"
     CDS             52..1353
                     /locus_tag="L1U99_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1213351.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            1380..1640
                     /locus_tag="L1U99_002854"
     CDS             1380..1640
                     /locus_tag="L1U99_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBN1213352.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(2639..3874)
                     /locus_tag="L1U99_002855"
     CDS             complement(2639..3874)
                     /locus_tag="L1U99_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBN1213353.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
BASE COUNT         1188 a          667 c          864 g         1417 t
ORIGIN      
        1 gcgttgtcat gcaatgaatg gttcatattt tattgaaaag gagtggtttt agtggaaaag
       61 ctgatgaaat gggtcgaaga gaaacttgtc ccaccaatgg caaaaattgg tacacagcgt
      121 catttattag caattcgtaa tggggttgtt tcaacattgt cattgatttt gattgggaca
      181 ttttttatgg tctttatcaa tttaccgttt cctggatgga atgaatttat tgccccttat
      241 tcggcaacga ttgttttacc ctttaggatg acgatgggat tgatggctat ttatgcaact
      301 tttgttatgg gttcggatct agctaaatca tatggattag atagtgtgac aggtggtata
      361 ttatctttag gaacgttctt tatgttacaa gttcctgtaa acgttttaac tcctgaagag
      421 gcacctcttg gctgggtctt acctatgagt tctttgggag catctgggat gtttgcgggg
      481 atcttatcta tgatttttgc agtggaagta tatcgtttct ttaaaaatcg aaatattact
      541 atcaaaatgc cagaacaagt gccacctgct gttgcccgta gttttgaggc attgattcca
      601 ggtgcagtca ttttaacaat tacttggctg attcgaagcg tcgcgggctt tgatgtaaac
      661 gctgccttat tatcgttatt cgagccttta accaatattt tagggaataa tttgcttggt
      721 gttttactac caatgttttt gatccatttg ttgtggtcat ttggtatcca tggcatgagt
      781 attgtagggg ctgttgttcg tccaatgtgg ctgatcatgt tggatgagaa tgcaaaggca
      841 ttggcagatg gtacagctgc cacccaatta ccctatatcg ctcctgaaca gttttatcaa
      901 tggacggtaa caattggtgg tgcaggagca acgatcgtgg tatctgtttt gtttatattc
      961 ttctgtaaat caaaattctt gaaagaggtt ggtcgttttt ctattattcc tggtatcttc
     1021 aatatcaatg agcccataat ttttggagct cctatgatgt tgaatcctta catgttcatc
     1081 ccgttcaact tagttccttt agttttgact attatcagtt attttgcagt caaattagaa
     1141 atggtcaata gatttactgt tttgccaaca tggacattac cagctccaat cggcggttat
     1201 ctttcagcag gaaatgactg gcgtgttgtt atcttgatca tgatcaacac attgatagca
     1261 tttattatct attatccatt tgtaaaagct tatgataaaa agatgctgtc agatgaacaa
     1321 agtcgtggag aaaacgaagt ccagactgtc taagtttggt ttttagaagg tgggaaacaa
     1381 tgtattggct gattttattt tttgttttta tctttttatt aacggctagt caccttatat
     1441 tgaatatgct agctacatat catattcaaa tcaatcgatg gatttgggca ctggcatcat
     1501 ttttgatcgt gattcttcca aagatcattg taccgcatat gaatgttttg ttttcatggg
     1561 ggacatatgt actttgtgga atttttgcta tcaattttat gatcgagcag catagatggt
     1621 ttgtcacatc gaagctttaa atgttctaaa agtggttgta acagaagtgg ttagcttcaa
     1681 gaaataagaa gaaatttacg aaaattgctt cttaaatttt tgtgaaatgt tggcttattt
     1741 ttcgtttggt tgaacttatt accgcagatg caagcttttg accaccgttt attcggaata
     1801 tgggactgtg acaaggcttt tgtcacagcc cttttttaca taaagattat tattgtttta
     1861 actgttttgg cagaaagaag gaggaaaaaa tggaaatttt atcagcaatg gatttagaat
     1921 tagtagatct actaccaaag tgatcaagtc aaatatagat ttgggagctt acaaccatat
     1981 agtaggggct gcagtatggt gtatgaatgg taatatgtat gatgtgagtg tttattcaaa
     2041 tcatgaaacg tgtatagaaa taattgtgct gggaatagca atcagtcatg gtgaacgtga
     2101 cttttagtgt atcgttgctg acgacataga acattctgac atgatctact caatatgtgg
     2161 ggattgctgg cagtttatat aggagtatgc atcggattgc gagatcattg tctcaacaga
     2221 agagggaggt tgattatcaa agataaagtg gtaaatccta catttgattt agtaattgtt
     2281 gaggggacta gcggcacaaa tctctacaaa gcgatgcttc tagatctata tgacacattt
     2341 taagaaaatg tatttgccta attattatgg tctttctttt gaagaaacgt tgagatgatc
     2401 caaccagaga aaggtgtcaa agaatttgac taagaataaa tggcagacgc tacctatgct
     2461 catttggata gcgtcagatc ttttatttta aggatgattt tgtgtttttt agacaccgta
     2521 atttaagtaa ctctaacttt tcaatccact atttactttt tttgtatttt cactgtctgg
     2581 gtctcgaata gcgaaattac tgatgagtct ctattaaaaa agctttttct acttgaaact
     2641 atattgggtg gttgctcagg aaggtttcga tttcttgaat tgcttgttgt ggaccattta
     2701 ttggaaaaac ggcttgcagc gtgcgtgcct gctgacgaat cttgggtgaa gaaacttcgc
     2761 gcagagcaat ctgcagtttt ctttcagtca ctggttttgt gagggcgatt gcgtttccgt
     2821 attttacaca atagtcaata ttacagcttt gctcaaattg catccccaca ccgataaacg
     2881 gtttgccgga ttcacaggca gtttggacgg tcccttcccc gccgtggata aaagaaaaat
     2941 caatgaattc atgcaaaaga tgactagaca gatattctgt tattaaaaga tcttctgagt
     3001 cagattgaat gtcatcaagc agatagtcaa taggtgcaat aaccgctaga tccggttgtt
     3061 tttgtaagaa gaacaaaatt ttgcgtaaca tacgcggatt gcctgaacta cccattgcga
     3121 aatagataat acgttttctt tcttgttgct ttcgctgtat aaaagttagc acttcttcag
     3181 gcaaggaagt actgagctta gcaaaaattg gaccaacgat tcgataattt tccggcagct
     3241 gttcttcttc caaaaatagt ttaggcgttg tgatgagatt tagatcagca tccatcattt
     3301 gtaaacttgt ttttggtaaa ggaagcattt ctttttgtgc agcgtgtttg aaggcattgg
     3361 ggatccatcg ggtatttact atacgctttt ttgtccagtg ccaaagggga ttgcttaaag
     3421 ggccgaagaa acgtaactcg tggggcatca gcgcatgctc tgattgaaaa aaaggttcac
     3481 tcaaagcata gggtttaaca tatactaaag gaatcttttt attgcgggcc gataaaaaaa
     3541 ttgtcacatt cgaacctgtc acaatcagtc gaggctcaaa cttagcaatc agactctgtt
     3601 cactagtgat acgagaggca accatttctt tggtaaaagg gtttttaagt gtacgcaact
     3661 ggtcaaattt tatgatttgt tcttcttgtt ttttcgtaag gatcggcgct agtaaatgat
     3721 actcaaagcc actttctgtg atcaaaggag caaaagtttt agaaaagcca aagaatacac
     3781 agtaataacg gtctttcata gctttggcaa cctcaatcat tcgtgttgtc tcagctaaat
     3841 tgaatactgc aggagcaaaa agaattgtct tcatgaaatc ctccttattg gaatgagtct
     3901 atcccttcgt ttcttactag tatactaaaa aacacagcgt tcgagtagcc tatgtatatt
     3961 ttgaatatta aactgtctct cgctgttttc acaacttcta aatttaaatt ttgtaatcaa
     4021 gttgaaactc caattttcaa aaaaacacgc aacaattttt tgatcgattt atatgttgtg
     4081 ccagataaat acgagaagtt gtgtcattaa aaataaacat gagaacataa aaaaat
//
LOCUS       DAFLVO010000142         4067 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.147, whole genome shotgun sequence.
ACCESSION   DAFLVO010000142 DAFLVO010000000
VERSION     DAFLVO010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.147"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            86..1435
                     /locus_tag="L1U99_002856"
     CDS             86..1435
                     /locus_tag="L1U99_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1213354.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1563..2153)
                     /locus_tag="L1U99_002857"
     CDS             complement(1563..2153)
                     /locus_tag="L1U99_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBN1213355.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2300..3652
                     /gene="brnQ"
                     /locus_tag="L1U99_002858"
     CDS             2300..3652
                     /gene="brnQ"
                     /locus_tag="L1U99_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBN1213356.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1173 a          744 c          789 g         1361 t
ORIGIN      
        1 aaaattttgg aatcttagtt gtgtttttca gaaaactctc ttaatatgga agtaattaaa
       61 cttttttagt taggatgatt taaaaatgaa tgaagagcaa gaactgcagc gtggactgaa
      121 aaatagacat gtccaactga tttctattgg cggagcgatt ggaacggggt tgtttttagg
      181 ttccggaaag tctatccagc tagctggccc ttcgatattg ctcgcctatc ttattactgg
      241 atgcatctgt tttttcatta tgcgtgcgtt aggcgaactt ctgttatcaa acaccaataa
      301 ccattctttt ctggattttg ttgcagaata tcttggcaaa aaagcggctt tcatcactgg
      361 ctggacgtat tggttctgct gggtatcgat tgcaatggcc gatttaacag ccatcggaat
      421 gtatgtacgc tactgggcgc ctggtgttcc tcagtggctt cctgaactga ttgcattagg
      481 tcttcttctt tgcttgaata tggtggctgt ctcattgttt ggtgagttag agttttggtt
      541 tgcattgatc aaagttgtag cgatcattgc ctttatcctc gtaggagctt atatgatcct
      601 cacccactat acgacagata ttggcacagc cagtatcacg aatctatggt ctcatggcgg
      661 attctttcca actggtgcaa aaggatttat cttagctttc caaatggtaa cctttgcttt
      721 tgctgggata gaattagttg gattagtcgc tggagaaaca gaaaatcctg aaaaagtgtt
      781 gccggaagct atcaataata ttcctatcag gatcatctta ttttacttag gatctctttt
      841 tgtcattatg gcaatctatc catggaacag cttgaatcca gataacagtc catttgtaga
      901 agtattttcg gaaattggga tcacgattgc tgcttccttg atcaatttag tcgtattaag
      961 tgcagcagct tctgcctgca acagtgcaat atatagtaca ggacgtatgc ttcgttcttt
     1021 agcgcaagaa ggcagtgccc ctaaaaaatt caaaaagtta acaacacatc atgtgccagg
     1081 gaatgctttg acattttcta ctatcgtcat tttcatttct gttatcttga attacgtgat
     1141 gcctagtgaa gtattcacac tagtaagcag tattgccact acttgtttct tgtttatctg
     1201 gagtatgctt gtctacacgc acatgaaata tcgtaaaagt atcctcggca aaaaagctca
     1261 ttcatttaaa atgccgttgt acccatttag taattatctg gtatttcttt acatggcctt
     1321 tgtgtgtgtc gtcttgttcc taggaaaaga tacgagaatc gctttattac taacacctgt
     1381 gtggttcttg cttctattac taatctatca tatgaaatat gaacgtaaga agtaagaaag
     1441 tagttgtgac agaagtggtc agcttcgaga aataagaagg aatttacgaa aattgcttct
     1501 taaatttttg tgaaatttcg gcttatttct tggagataaa agcttctgtc ccagcctctt
     1561 ttctatttcc ccggaaacaa ccgctgataa taggcatctg cttttttata ggaaaaaatc
     1621 caaataccag atacaaaaaa acgtccgaat aacccgatca acggtacaaa aaagacaccg
     1681 gcaatcaagc ataagttaat catcatggag ataagacttc gacggtcctt tgacaaaact
     1741 ctcacgacat gggaatctgg tttatttgct ttcatgattt gcctcatcaa gataccaaaa
     1801 gaaaaactcc acatcgtgta tactaagaca taagccatct caggccaaaa agcttcaggg
     1861 ttacgcccga cccaactagt aacagaagga cataaagtca gccaaaagag caaaaagata
     1921 ttcgaccaga ccactcggta attaattcgt tctgccatct gaaatatacg atgatggttc
     1981 acccagatca ccgcaacaaa tataaagctg atggtataag ctaataatgt atttcggatg
     2041 acccataaag aatgaaagct agatgtatta gggatcttga tctctaatac aagaactctc
     2101 aaaacaatgg ctaccactcc atcagtaaat gcttctaatc tcgactttgt cacgatgatt
     2161 cctcctcaga tgattcagcg cttttatttt atcacttacg ttattaaata accatcgttt
     2221 tatataggga attttctgaa aattgttgca tatttttcga aattttgtta cttttaaaaa
     2281 aaccgtaaag gagttatgta tgacaaaaaa attatcattt aaagactatc tttttatagg
     2341 ctccatgctt ttcggtctat tttttggtgc tggaaatctt atctttcccg ttcatttggg
     2401 tcaagaagca ggcgctgcta ccttttgggc gaatctaggt ttcttggtta ccggtatcgg
     2461 tcttcccttc ttaggggtga ttgccattgg tgtatcgaaa agctcaggtg tatatgaatt
     2521 agcaaaacgg ataaatcaaa catatgcgat ggtttttacc atcttgcttt acttagttat
     2581 cggaccgttt tttgctttac ctcgccttgc aaccacatct ttcgagattg gtttagcacc
     2641 atttatcgat cctagcagac agacgctata tctagcaatt ttcagtattg tattttttgt
     2701 gctggcttgg tggttttcaa gaaaaccgac aaagatatta gattatgttg gaaagttcct
     2761 gaatcctgca tttttggttt tattaggtgc tttgcttctc cttgcttttt tgaatccact
     2821 aggttctgta aatcaagcgc ctattcagcc aaattatcaa gagcatgctt ttttcacagg
     2881 gtttactcaa ggatataaca cattagatgc gcttgctgct ttagcatttg ggatcatcat
     2941 tgtcacaaca atccaaaaca tgggtgtaac aaaacctgct gaaatcgcta aagacacgat
     3001 caaatctggt gcgatcagca ttatattgat gggaatcatt tatactttgc tcgcttattt
     3061 aggtgctatg agcttaggta gctttgctct aagtgaaaat ggcgggatca cgctggctca
     3121 gattgctgat cattatttag gtacttatgg cagtatctta ttagcattta tcgttatatt
     3181 agcttgcttg aagaccggta ttggtttgat tacagctttt gcagaaacat tcacagattt
     3241 gtttccgcaa agaaattacg cattctttgt tgcacttgct agtatccttc cttgtttagc
     3301 ggcaaacgta ggcttgacga atatcattca attttcgttg cctgttttga tgttcatcta
     3361 tccattagca atgacactga ttttactagt gttagttggt cctttgttta agcagcgtac
     3421 ggctgtttat cgaatgacta cttattttac attgattgct tcgatttttg atgggttgaa
     3481 cgcttgccca gaaactatca aacaaacacc tattgttcaa aatcttttat atgttgcgga
     3541 aagctacttg ccgtttttca aattggggat ggggtggatc gtaccagcag ttatcggttt
     3601 tgttatcgga ctgatttgga gtttcgctaa gaaagaagaa gtagcagatt gataaaagag
     3661 gttgtgaaag agacgttcag ccttgagcaa taaaaagtaa ttttgaaaaa tggcttctca
     3721 catttttgca taaatttgac ttaataccga gaaactgact tttgaacacc gtttattgag
     3781 aggtcgtgaa aaagccgctt agtttcaagt attaagaaat attttgtgaa aatggcttct
     3841 cacatttttg cataaatttg acttaatacc gagaaactgg cttttgaaca ccgtttattg
     3901 agcgtctata aactgacctg agtattagag aaacaaaacg gcaaagtagc tccatatact
     3961 ttgccgtttt gttttgaact aataccgaag agaagctgat caaacaacat ttcttttata
     4021 atatagattt tagacatata tatgatataa aaatagtttt cgcaaaa
//
LOCUS       DAFLVO010000143         4047 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.148, whole genome shotgun sequence.
ACCESSION   DAFLVO010000143 DAFLVO010000000
VERSION     DAFLVO010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4047
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.148"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..929)
                     /locus_tag="L1U99_002859"
     CDS             complement(<1..929)
                     /locus_tag="L1U99_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32"
                     /protein_id="HBN1213357.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIEN"
     gene            complement(933..1343)
                     /locus_tag="L1U99_002860"
     CDS             complement(933..1343)
                     /locus_tag="L1U99_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1213358.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            complement(1361..1852)
                     /locus_tag="L1U99_002861"
     CDS             complement(1361..1852)
                     /locus_tag="L1U99_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1213359.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            complement(1862..2653)
                     /locus_tag="L1U99_002862"
     CDS             complement(1862..2653)
                     /locus_tag="L1U99_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1213360.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            complement(2646..3419)
                     /locus_tag="L1U99_002863"
     CDS             complement(2646..3419)
                     /locus_tag="L1U99_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1213361.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            complement(3575..>4047)
                     /locus_tag="L1U99_002864"
     CDS             complement(3575..>4047)
                     /locus_tag="L1U99_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1213362.1"
                     /translation="FYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLF
                     TIEGASTKLRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIG
                     DGITNEHLKEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
BASE COUNT         1270 a          834 c          544 g         1399 t
ORIGIN      
        1 aaattctcaa ttattttttc aggcagttta acaccaagag ttttgtctgt cttttgaata
       61 atttgatgtg gaacaagtgc accgccccaa tcccagttat tttgatcgtt ctccccttct
      121 tttgttgcca cccagccagt tagaaaacgg ccagtttcat tagttccgac tgttcttgct
      181 gcataatagg cttttccgtc gaaagcttcg tctactggtg atttccaatc tgaaaataat
      241 cctgctccga ctcgatattt agtcttttta tcttcacaat actctgaaaa aagtaaatac
      301 cacgttccat caatttcaaa tatatcaggc atttcaatca tgttaaattc attattagcc
      361 cagtagtctc ctttgaaatt ccaatctttt aaatcttcgg attcaaaata gaccaatctc
      421 cccgtcggct ttttcttact tgctggtttt ctagctccta gtatcaaaac gtattttcca
      481 tgatcttgat caaaaattgc aaaaggatcg cgccaatcat tcttatcata tccttcttga
      541 ggaacaagtt ttgctgcttc gccatccttt ttccaatgaa ttaaatcttt agaacttgca
      601 atcattaaca cttctgaagt ttttccatcc aacttagctt tgcgattatg tccagtatac
      661 aaagctaaat actcattgat tccttggaca atacttccag cgtaaatgta ttgatcaatg
      721 tcatcgttgc caccacgatg aattacttcc ccgtattctt caaatttcac aaaatcagtg
      781 gttgtaacta gtgaccaccc aaaaggatca gttaaaggtt taggatttct cgtatctcgt
      841 tgatgaaata gataaaaagt tccatcttta taaaaaggca tgcaatcccc aaaccaaaaa
      901 tctttaggct tgtaaaaaat tttttgcatt tatcactcat cctcttcgtt agtatgtctt
      961 tgcatatctg caagacacgc aattgtattc atatttctta gattttcgat gatatcatcg
     1021 cttttttttc cttgtaatct caaattgaca gcctcaatca aaattcctaa attcatgcca
     1081 ccaagaagtt gaaacccatt ttgaaatact tcacttcttt tagcaaattc gttgaaaggt
     1141 gttccaccaa tcaagtcagc aaataccata acttcttgat tttttacttg agaaactatt
     1201 ttttcaatgt tttcacggaa ttcttcaatg cctgcatctc caagtgttac cacatgacaa
     1261 tttaaattat cgccaaaaaa catttttaat gtatctacaa atccaatggc aatatttcca
     1321 tgagatgtaa ttataaactc catccactca tcctctgttc ttaataaata aaatccttta
     1381 aaaattcttt tgaatctcta ggagtttgta tcactgtcac ttcaactcca tcactaatta
     1441 gttctttaaa agcctctctc tcttcttcag taatatttat cgtcggacgg atgcgttctg
     1501 ttccattcct tcttgataaa tttcctacgt ttacacttgt tattggtaaa ccgttatcaa
     1561 tcaaaaattt aacatcgatt ggagaaactg caacaataag aactttttgt ccttcatatt
     1621 taccagaaag aatattttta actgctactt cccttgtaat tattgaagtt ctaacattag
     1681 gtggtgcagc gaggcgaact acagcttttt ttacgtcatc attggctact tcattattaa
     1741 taaccataat tctgttagca ctcaattgat ttgtccattg tgttgctact tgtccatgaa
     1801 tcattcgatc atcaatacga acatgtataa tacctttcat tttttcatcc atattcaaca
     1861 cctacttcaa aatatttaac gctcttaacg caatagaaac tactaagatt aatagaatta
     1921 cataaactgg tttaaccttt cgtcctaaca aataatacac aattgctact acacatgcag
     1981 gtaataaacc aggcataact tgatcaaaga tttcatttcc ggtcattgtt aagtcgcctt
     2041 gtttaaattc aaagccaaca ttcactttta caactgtggc aatgagtgca ccgaccacca
     2101 ttaaccctaa aattgatact gcatcagtaa tagactttaa ttttgtttca atttgagtta
     2161 gtaggctcgc acccgattct ttcccagcaa ggtataaagg ataagcagta atccttaata
     2221 aaattgatgc cagtatccac aaaataattc caacaaaact accttccaat gccatattag
     2281 ctgcaattgc tccaaaaata gtccatggaa taactacaaa tacactatct ccaattcccg
     2341 ctaaaggacc cattagacct gttttcagag cacttactgc ttccaaagac ttattttttt
     2401 cttctttttc aattccaaca ttcataccaa taatgtaagg cgctgtatac ggcgtagtgt
     2461 taaaaaattg taagtgagct aaaacggatt gtttcattcc ttcaggatca tctttatatg
     2521 tgtccttgat aaaaggaagc atagaatacg cataacccaa cccttccatt ttttcataat
     2581 ttaatgaagt tgcaccattg agaatccacc ggaaaattac ttgtttgtcg atttttgtca
     2641 gtttcttatt catcttcgtc aaaacctcct gttgcagctg gtgctacttg agtattattt
     2701 gatctatttt tatatacgat tagtgcgatt gcagcgccaa gtaacgaaat ccctaaaatt
     2761 ggtatttgga aataaactgc caaaacgaaa ccaactaaca aataggcaaa gtaatctttt
     2821 gtaggtaaat atttaagtag cattcctatc ccaacagcag gtaatagtcc ccctgctacc
     2881 tttaaaccac cggtaaccca ttcaggaata taattgattg cacttcccac taacgttggg
     2941 cctaatatca cagttaacaa aacaggaatt ccagatacaa agcttgtatt aattgatgcc
     3001 aaatattgca tccactctaa tttttgataa tcttcttttt gtgcgaattt ttctgccttt
     3061 tgttgaaaaa aaatgtttgt tgaccacttt agaacatcta gttgtacaat taacattgct
     3121 accggtattg ctaaagttat tcctatagaa gcatcctggt tagttgagat tgctaaataa
     3181 gtaccgatca atgctgctgt ttgataatcc ggtactgatg caccaccaaa actagtaata
     3241 cctagtgtca ttaattgcaa agtcccaccg atataaagtc cagtttgaat atctcccata
     3301 ataagtccgg tcaagaaacc tgcaacgaca ggttgggagg ttccgatttt gggcccttcc
     3361 ttatcccagt taatgaaaaa tccatacaac acaactaaaa atgtttgcca aaacgccatt
     3421 ttgttctctc ctttcttctt atacttttat ataagcaatt actgtgccaa ctaacattat
     3481 ccaataaagc gggaaaatac agtaaatatt aattaaatga gcgtctaaat atactttgga
     3541 caccctttca tttttttaga cgctagtatg ctatttagaa aatagtctgc tcaaaaattg
     3601 tatagattaa ctcatactct cctttgggta tttcaataca gtaaatatct ttgatttctg
     3661 aaaaaaaatc ttttgataca tttaaaaaag tatcaaatag ttgcgctccc tctttcaaat
     3721 gttcatttgt tattccatca ccaatcataa ttcgttcaat cattccagaa agatgtagaa
     3781 atagattaat tctcagaaaa cttgggattt tgacatcgta atatttttca tacaaatata
     3841 gtactttttc tatctcattg aatacttttt tggaatctaa aaagcgaagc ttagtactag
     3901 cgccttcaat agtaaagagt ttaactaatt catttaagca gaactcacag ctatccgagt
     3961 ccatatactt atttaatttt tctaaggttt gattcccatt aattagattt tctaaattta
     4021 aacaatcgat tccttgaatg taaaatt
//
LOCUS       DAFLVO010000144         3972 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.149, whole genome shotgun sequence.
ACCESSION   DAFLVO010000144 DAFLVO010000000
VERSION     DAFLVO010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3972
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.149"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(620..1177)
                     /locus_tag="L1U99_002865"
     CDS             complement(620..1177)
                     /locus_tag="L1U99_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213363.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(1356..1967)
                     /locus_tag="L1U99_002866"
     CDS             complement(1356..1967)
                     /locus_tag="L1U99_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213364.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(2080..2337)
                     /locus_tag="L1U99_002867"
     CDS             complement(2080..2337)
                     /locus_tag="L1U99_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213365.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(2934..3212)
                     /locus_tag="L1U99_002868"
     CDS             complement(2934..3212)
                     /locus_tag="L1U99_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213366.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(3246..3497)
                     /locus_tag="L1U99_002869"
     CDS             complement(3246..3497)
                     /locus_tag="L1U99_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213367.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         1203 a          815 c          526 g         1428 t
ORIGIN      
        1 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
       61 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctaagcaaa
      121 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
      181 ttttcataca aaatttctca atttccctta acgagtaata tttatgtacg gtgattctca
      241 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
      301 ttttatgtat gctgttagtt gattagatgg tcatttgttg agctaggtcg tttattttaa
      361 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
      421 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact attaactcct
      481 ctcagctaat agttgctctc ttttttattc agattcattt ttgctgatca cagcctagta
      541 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
      601 atggattagt agatttcgat tattcaaagc gattttctat tggtggatcg tgttcccaac
      661 taataagacg gattccaaac ctatcgtaca gatcttctaa accacttata aattttgcac
      721 ctatttcagg tgttttattg cgtggatatt ctattgttac gccattaaat ggataccaat
      781 taggattagg ctctcttttt ttctgtacat ctcccataga atagttagca ctttctggga
      841 cataatatat tcttcgacca tcctctaatt catctaataa gatatttcgt gatcgtctat
      901 cacttgctaa atgtagacgc cacgtgcgat accatgccat gctacctgca tctgcagaaa
      961 atccatcaaa taatgcaaca attgtatctt ctatcacaat cctttcccca tctacttcat
     1021 attctaatct aaaatcaaac tcccctcggg taatttctgg tcttggtggc ttaggaccca
     1081 atattattct acttaaaacc gcattcgttc ccagatgaaa cacagctata acaacaataa
     1141 tgattaatat tttgtttcta tttgataaat ttctcattat tcgcacatca cctctacatt
     1201 ctcacatatt agttcgtaat actcctttaa tatcaaaata tctactggtc gtaataatat
     1261 tcgctatgaa ttcctactac tcgtataaga aaggccaaat catcagcttt tacttgctga
     1321 tgatttggct tgtttctatt tatcgtaatt gttttctaat caccaaaatt gttaacaatc
     1381 ggttcagata tttcccagtt gattaaggta attccgtatt gtgtcaaaac ttcttgcgct
     1441 tctccgaaat taagtacagt tcttatgtat ccactttctc ctaatataaa gtctacctct
     1501 cttttaaaac cttcctcgag atttctaagg gctatatgtg gttttaatga cattgattgt
     1561 acattttccc ccatataata ttgcgcactt cctcgactaa aatagattcc tagatcgtcc
     1621 ccaaaaggta gatcttctct accactagct aatctacttc tccatcttcg ttctcttttc
     1681 atagaacctg cgctgaactc acacccgtta aactcagcta tgacagtatc ttcaattatg
     1741 ttaatctgtc catctagttc gtattcaatc ctaaatggaa attctccata ggtgatttcc
     1801 ggttcgggta ttttaggtga gattaatgca aagaaaggaa atattaagct tggcaacatc
     1861 aaaaaaactc ctcctatgat cacaattccc gatgtaatcc aaaatataat ttgtacaatt
     1921 ctcattgatc cattgtattc cattttattc cccctattac tattcatatc cgcctatcta
     1981 tatcgatctt ccaatgcaga gataattgct tccatacctt gattttttac tgagttacct
     2041 atgcgagata tcattctcca ctaaggtgca tcatattgtc tatctaacat gattaattct
     2101 ccaataggtg tatactcctc caaaaacaac atttaatgca tctccctcga caacataagc
     2161 taccatgttt gctgtatatg tgtttgagtc taattcataa gcagataaat ttactgtcgc
     2221 tggattaaat ataatcgcat tcgtatttat agctactgaa tttgctgctt cagcaccacc
     2281 ttttgaatgt ccgatcattg tgatttcaat agtaggattt acgtggacag ccctcaccgt
     2341 ttaccctgac cattatagaa atcgcttact tttttgaact acgcaacaaa ggatacaatg
     2401 ctcctaactt cactgtctcc atttttgtcc actaaggaat ataaaaaata ggcattaatt
     2461 catttaattc ggtcacaaca cgttaccttt taaatcatta tactgtatct catacattat
     2521 tatcaataaa ctattataaa aatgcaaaaa atgctttatc aatctatttt gtaattggtc
     2581 ataatatcat tgaaatcata ccctgtatcg atttttccta tgaatctcgt ctatttgtga
     2641 ttgacgaaaa agaggcaaga cagacactgg aatggtaatt ttacccacta ttttgctcca
     2701 actatttgta atcgtaccca cttttgaaat accgagatga tcattttaat tgatatgctg
     2761 attcccaagc aaaaccccaa gaaattaaat gctctatcgc atctagcttc ttgggttttg
     2821 cttatataaa ttccaacatt taaatttttt atgctgttcg gtctcagaaa tgccgttttt
     2881 gcttatatca caatatcaag atgtcaaatt attcgtgttg ccgatgactt tgattaattt
     2941 ttttcaaatt gtttattaag actaatgctg tctttttgca gataccaatg ttcgaacttt
     3001 ttaacattat catatgatcc tgcaagtttt aacttcttac cattagatgt tatcaaagtt
     3061 ataattaacc ttgccttttt cccattagga tcttttattt tatgaatttt ctgcaggtaa
     3121 tctctcctaa tggcagctat ttttacctca tcagtgctga taaaccattg atcatccaca
     3181 tacatactgc ctgttatgtt gtgtttttcc atttcttccg agaacgaaaa gtttaaggct
     3241 cgttcttact tccaaagttg aatgagtcca tggattggac ttagtgtgag aattgagaac
     3301 aacaataaga atccatatcc tcccgcaaac atccctaagg ctatactgtc tctccatcca
     3361 taagtaggat tagaagagaa aagagtcacc gtttgtaata atatgaaaag gaataatcca
     3421 gcacaaacac caaagataac aactccaaac attgaatttt tatacaatga ccatttattt
     3481 ataggctttt ctttcatttt acttccccct actgttctgt tcacacggaa tgaattcaaa
     3541 gttcataagc cctcctcttt gaacatatga atacgacttg ctaactatac tttaaaaaag
     3601 cttgttttaa gcggttatag gcgagttgta atctctattc atctcattag caaataactt
     3661 gccgaaaagt ctactgaaat taaagcagat agtggaagaa ttatttagcc aggatagaca
     3721 ctatttgtga aacacatgtc tttacttttg aaattctatg atgaaaagcc ttggaataca
     3781 gtagctctta attggtaata ctttttccat tataaataac ctcttttcat tttatattta
     3841 tcccctctaa aaataatatc taatctaata ttttaaactt atatttccct cgctgtgcta
     3901 atagagcatt actaaataaa tagaaactag aaaaaagcat tacgcctgcc agaataaacc
     3961 aattatttgt at
//
LOCUS       DAFLVO010000145         3893 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.150, whole genome shotgun sequence.
ACCESSION   DAFLVO010000145 DAFLVO010000000
VERSION     DAFLVO010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3893
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.150"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..353)
                     /locus_tag="L1U99_002870"
     CDS             complement(<1..353)
                     /locus_tag="L1U99_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213368.1"
                     /translation="MKKFKKKIYLGLVVGVSMFGFMAHTKQVTADTNQKERIMSQLDD
                     SQIEYVPNELIVSLKATQRISTEKNKPQNLLGVKVMVEKDLTLRINESDYNKRDQVLL
                     VKLNEEISVEEAVRT"
     gene            complement(613..1161)
                     /locus_tag="L1U99_002871"
     CDS             complement(613..1161)
                     /locus_tag="L1U99_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213369.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(1162..2019)
                     /locus_tag="L1U99_002872"
     CDS             complement(1162..2019)
                     /locus_tag="L1U99_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBN1213370.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(2305..2591)
                     /locus_tag="L1U99_002873"
                     /pseudo
     CDS             complement(2305..2591)
                     /locus_tag="L1U99_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2581..2910)
                     /locus_tag="L1U99_002874"
     CDS             complement(2581..2910)
                     /locus_tag="L1U99_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBN1213371.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(2987..3259)
                     /locus_tag="L1U99_002875"
     CDS             complement(2987..3259)
                     /locus_tag="L1U99_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBN1213372.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(3259..3522)
                     /locus_tag="L1U99_002876"
     CDS             complement(3259..3522)
                     /locus_tag="L1U99_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBN1213373.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            3756..>3893
                     /locus_tag="L1U99_002877"
     CDS             3756..>3893
                     /locus_tag="L1U99_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBN1213374.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LK"
BASE COUNT         1165 a          784 c          498 g         1446 t
ORIGIN      
        1 aatgttctta ctgcctcttc cacactaatt tcttcgttca atttcactaa taatacttga
       61 tctcgcttat tataatcgct ttcatttatc ctaagagtca aatctttttc caccataact
      121 tttacaccca ataaattttg cggtttattt ttctctgttg aaattctttg tgtagccttt
      181 aaactgacaa ttagctcatt gggtacatac tctatttgag agtcatctaa ttggctcata
      241 atcctttctt tttggttagt atctgcagtt acttgtttag tatgagccat gaacccaaac
      301 atactcaccc caacaaccaa tcctaaatat attttctttt taaacttttt catctacatc
      361 tcctcctaat agttttattt tagagttagc tctattactt atttactaac tcaacaacag
      421 attatcatac acttgttaat gaaatcacaa tatctcatta aaacacaccc taaaatcata
      481 accgttccta tgctcatttt ttggattttt taatcacgta accagaaaaa taaatcccct
      541 ctatttcacg caaatcaaag aagaactaag taactaccgt ttaaaggtag ttacttagtt
      601 cttctttgat tattatctaa ctttattatt cattccccac cctttgcgca gtgagtcttc
      661 ggtatcttgt tttatctgac tggtagttct tattatttct ccacgatcat ctaattctgg
      721 aacaattgga tatttttctc tgaacaagtc tagttctttc accacgtcat taaacaaatc
      781 ttgcttatct tcttgcgtaa gattctgttt aatatactca tctaaagctt ttctaagcaa
      841 ttcatctctt gtcatattag tctcatactt ttctactaaa actctggaag tcgcatttaa
      901 caaagtcgac agttttaaag gatgcttggt ggaataaacc ttatcaaact ttctgattgg
      961 tgcgccaact ttttttgttc ttcctctact ctgtctttca acattggagg aagtttttat
     1021 ttcttgaact tggtgcactt ctaattgctt attttcagat ggtgtaattg cttgctgctt
     1081 tttctttgct tctgcttctt tttttatttt ggcgagtcct ttgttgttcc caaaaatatc
     1141 aagtcctttg atgtcagcca attactccac ctccgcatac caattctcgt gttcttccaa
     1201 ttctttcaaa atactgataa ataattcgtg gcttttgcga tcccattgtt ttaagagacc
     1261 tttctttgtc ttctccatcg taatacctga tccgtcgtat cgttttaagc gcgcattttt
     1321 gagtacaaca tttttaatca aatgttcccc ataaatctct tgggcttgtt tatacatttc
     1381 ctgatctact gcgtcaccgc tttccaacat gaaaggaata acaccagcaa catataaatt
     1441 tgtatcaaat tctttcacaa aaaagtccat atactcaaga tattgcatcg catttctcat
     1501 cgattttact tgggtctgta agacgacgat tgcccaatcc gcaatgtaca tcgcggattt
     1561 actatataca gaaatagaag gtgggacatc taaatagatg acgtcaaact catcaaataa
     1621 tggttctagc ttttctttca tatatttgaa ttgggataat gaatcattat attggtcttt
     1681 gatccaatca tcatacattt caaaggacat gtctgctgga agtatataga ggttattgat
     1741 tactttatag acagcctctt taggtggaag attgtttatc aacacgtcag tcacagtatt
     1801 ttcgtaaaca atcggttcac cttctccgcc tccttcttcg ttagtgaagt tcatatgcgt
     1861 taagttcatc acatcagaag tatttccttg catatccaag tcaattatca aggttctttt
     1921 tccttcatta actgctgatt caaaccctaa catttgcgcg cacgtacttt tacctacgcc
     1981 acctttaaaa ttaccgatta catatttctt cgctaccacg ttcctacctc ttttctttta
     2041 gcaatattca tttgatacta ttataacata tttattttta gttactacca aaaaaaagat
     2101 atatatgtac taccttataa ttaataagta aaaggtagta cataaataag gaaaagctga
     2161 aatatattga tttatagctt tcctcaaagt aatgacgtta tttaatttat cgagaagcag
     2221 agaatactcg cgactttagt catgtagacg aatcagattt tcgataaaaa agaagccgtc
     2281 cttcttaaga acgacaacaa atcactagat taattttttc aactgttcat aaaagttttc
     2341 atgcgttcca cataacaata ctggaataac cttgttttct ataatctcgt aagctactct
     2401 atatgttgtg cccgcatatt tgaacccact agaccaaata cctgataaat ccccagtttt
     2461 ttgttcaccc ttatatggat caatcgcaat ttcatcataa attaaattca aaaatttttc
     2521 tttcaatggc ttctctttta gctttttaaa tacttaatga catgttttga aggaacgatt
     2581 tcataagcca atttctgttg ccaactcctc tttagtcatt actttagaat tagtaagtgt
     2641 atcttcagca atatctctaa aggaagaatg cattttgttt tttctattct taaattctac
     2701 aagaatctca tctttatcgt agccttctgc aattatatca gacaaaatat cttcgctaaa
     2761 atcataaaat tctttttgtg gttcaacaaa ttcataaaga ataccattct ctaccaactt
     2821 tgcttcaact tcgactccat taggaacatt aaaatcttta ggtactgtca acatgattga
     2881 attgccttgt tttcttgttt ttgtaatcat ttaaatccct catttctaac agtatgtaat
     2941 tacttagtaa atacattata ccacgagata atgtatttac aagtaattac tgtgactcgt
     3001 aatgcgtcct tgctgaataa atttcaacca cgtgttcatc ttcatctacc ttataaacaa
     3061 cccggtgttg tctattcaat cttctagaat acctaccttc atgtgtaggt tttaacttct
     3121 caaatgattg ggtagggaga tagggatctt cctttaaagt ctgaataacc ttctcaaatt
     3181 gaggtttcaa attagactgt ttgattttct ttaaatcagc tttagccgag tttttaatca
     3241 tcacagaata gttattcatt ataagttatc ccaatcaatt tcatcaacat tagtaaatcc
     3301 actatcatct ttttctcgct tacgaacaac acccaaagtg cctatttgct caagtaatag
     3361 cgtttctttg attgctttcc aatcatccaa accaataagc accgcattat tttcactgcg
     3421 ctcactaatg atttcaattt ccgtatgatt ctcatttaca tctttcaaca acttataaaa
     3481 atttttccgt gctgagctag gatttaagac tgtttttgcc atatctactc cccctctaat
     3541 ttatatctcc attctaacgt acttaattaa gtacgtaaat tcgattgttt tgtttaaatt
     3601 ggagtaccaa aacagcattg taaagtgtta tccgtttcct ttatacccgt ggtgctagtt
     3661 aattttttcc tagaggaaaa tgtctaaaca tgttggtaaa tcaacaaaaa aacgcataga
     3721 gtagtctcaa aactcccaag aaatgaggac tacatatgcg ttcatcaaaa tatactgaac
     3781 attatacaga tacttttata acattcaagg aaattatgag aactgtttct aacatatacc
     3841 acaattgtgt accagataag attaaaaacc gaagaaatac tgatcaactg aag
//
LOCUS       DAFLVO010000146         3876 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.151, whole genome shotgun sequence.
ACCESSION   DAFLVO010000146 DAFLVO010000000
VERSION     DAFLVO010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.151"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(716..3865)
                     /locus_tag="L1U99_002878"
     CDS             complement(716..3865)
                     /locus_tag="L1U99_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBN1213375.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
BASE COUNT         1076 a          803 c          635 g         1362 t
ORIGIN      
        1 actaatacag gtagtcctct tttttgttat tttgatattc taaatcattt tttattggat
       61 tattcccttg ttcgatatag acccaaattg atctatcaat aattatcaaa ctgagtcata
      121 tagagacaaa aatttcaaaa atgacctgtt aaatggtcat cgaatatcat ttaaaatcaa
      181 tacgacggag tcagacacgg agtcaaaaca agcccgctga gagtaaaaaa tatatacagt
      241 cccataggta aagtgccaca ggactgtata tttttttatt tgagattacc tgaaatgatt
      301 ccatttactt tttatctcat tttttcctac tagttagtat caaatactct cctattttct
      361 caataaacta ttttgggtta catggtatct gaaacagcta aaaccttgtc attacagcaa
      421 aaaatcactt tatctccgtt tcatttcaga tacatttcac ttaagcggat tccaaaaaaa
      481 caaaagaaaa aggaacccct agttagccta tgctttttat tggttcctct caaaacacgg
      541 tcatataaca acggggtggg gtaaatgaat gaaaaaggtg gaggaaacat tattcaatag
      601 ctgtcttaaa tacttcgtta taaaatgtga acaaataaaa gacatctatc cctattttct
      661 acacttccac tttactacca tctttgaatc gtacaatttt cttaactctt ctcgtttacc
      721 tcaattcatt ttcaagtgga atcagctcat catctaacat tttacgccat gctcgcttca
      781 tttcttgtgg gtatttaaat ggcttcgctt ctggatggtt ggctttatat ccttcgtaat
      841 ccttactgtt gataattgct ttcatattag gaattggatc ttcacctggc atatattgca
      901 gattagaagc atgtaattct ttctcagaaa caaaccactc attggaaaag acatgaatca
      961 aatcatcact cgcttgtgta aaatagcgac gtttaatgac aaagatatct tcattactat
     1021 ctaaagtccc cacatcaaac gcatttaaaa tttgtcggta aacttctttg actccttctg
     1081 ttttattcaa tttagccaaa gctttttcaa tttcttctcg tgcatctgaa ctattcgccg
     1141 cataagttcc tagtaattga tcaatataag tagaatcaat atcatacaac ttcgtggtat
     1201 tttcactata aaattcgatc gtggaaaaat cttctccctc tttttctggt tcttcctcta
     1261 ttaatgaacc cttcacggtc tcgtacacgc caatttgttc ttccaaaagt tgaatttgat
     1321 tgttcaaggt tgaagatttc accatgtcat cattgtaatc gtcataagtc actaacgatt
     1381 cataagcacg attcaattct tggaatgctt tgacgtactc gatacggatt tcaagtggcg
     1441 tatgttcatc aatggattcc atggatgaaa cctcttttaa cttaccatat gcttgcttga
     1501 atcttttttt ggattcctga taacttggat aaatcaaacc cgattcttct tttgcttctg
     1561 aatacagttt tgtcgcatcc tcgacattct tctccattgt ggctggcttt cggaaagtaa
     1621 caattagtcc ttttgttttt tctggatacg tacggttcgt acgtgaaaaa gcttggatca
     1681 atcctgcata ctctagatta cgatccacaa atagggtttg aatcgtaggt gcgtcaaaac
     1741 ctgtcaatag acgatccact acgatcacta aatcaatttg tttcccaaat tgtttgaatt
     1801 ccgctctttt tcgtgccaaa cgattattga tgtctccgtt ataacgctca atgtctgcta
     1861 atgaccagga agtatcataa tactgattat attcctcaat aattttttgc atttcttctt
     1921 gttggacact tgaatctcgg ctgttttctt ctaatgaata ggtaatagcg attcgtggaa
     1981 aatcaggatc ctccatcgtt cttccttcac gaatgggctg attaggaaac tcttttgtta
     2041 accagtcagg ttctttcgtc atttctttga tcgctcgata atactttttg gccatgtcaa
     2101 tggaactcgt ggttaagatc gcagacttcg ttggacggcc atttcgaaaa tcaaattttg
     2161 tataggcatt gtctggacgg aacattttat gaatgacttt ttggatatgt tcatctgctt
     2221 caaaaacagt agggtccaaa taactttctt ttttgacagg ctccatttga tcaatcatac
     2281 gattgatctg ttccggtgaa tactctgcat atgtttctac ttcttttaat ttccgataga
     2341 ttttattctc taatgaagtc ggctccacgg tgttttcatg ctctacttga aatcctaaaa
     2401 ccgagccatc ttctaatgca ttcttgatgg tataggtatg caagacctct ccatactgat
     2461 catgggtcgt acgtgccaat tgccctttgg cttgtttccg attctcaggg aaaatcggtg
     2521 tacctgtaaa gccaaaccaa gtggatttcg gaaacatttt tttgatttct tccatatttt
     2581 cagcacttaa cgctcgatga cactcatcta ctacaaacac gatatgttgc cccattaatt
     2641 tttggaagcg attggttcct tttttctctt cttgtttttt tgcatatttc aacgccgcat
     2701 ctagcttttg acgggttgta ataatcacaa catttgcatt ggcatctgcc aacagagttt
     2761 cacttaactc tttggcactt cctgttccca cgatcaagct attcgctttg gcgttcccgg
     2821 aagaaatccc agtattaaat tccgaagcaa atttcgtaaa ctctgtggtg gtttgattat
     2881 ctaaatcttt gcggtccact aacatgatcg tccgatcgat ccccgatttt cgtgctaaaa
     2941 gcttagtaga tacaaaacta gtcaacgttt ttcctgaacc agtcgcatgc cacacatatc
     3001 ctgattgatg tttatttgca gcaataaaca aggcttgaat cgcatgtact tgataaggat
     3061 gtaacaccat gaggatttta ttgtcttgat cttcactgac aatcgtataa tccgcaatca
     3121 agcgatgagc atccgggata tttagcactt gtttgcaaaa ctcatataag ttttctacct
     3181 ttttattatc tttcgttcgc caactaaata aaaacttagg atgcaaatcc tttggtaagg
     3241 catttgcaaa ataccgagtg gtttgttcat tggaaaccac aaacaactgt aaggtcgaaa
     3301 agatattgtt ccgaaacata ccttcttctg catatttttt gatttggtta aacgcctgat
     3361 aaaaactatc ttttgcggtt acttgtttca gctcgatttg gacaatcggt aatccattga
     3421 tcagtaaggt gacgtcaaaa cgtcgatccc gtgcttctat gttacttcca cgttttgcaa
     3481 tttgatggac cacttcatag gtagagattc ctccaccaat gtcttgatta gaataaagaa
     3541 tgagcgagac agaacccagt tgcggatctt cccgttcaat cgtgatccga gccattccat
     3601 tttcaccttt taaccatttc gcagcatcaa agggggtttt cgttcgtagt aacaattctg
     3661 ttttgatcgt ttcaaattct ttatcggtca aaggaaaatc attcagttct gcttgattat
     3721 ttgagatgat tttttggcgt aaattgaccc aaagatcttc ttctgatttt agatcgggac
     3781 gatacgtcca ctgattatgc ccttccccca atacacggat caactgttct tcgacttccg
     3841 cttcctcacg gtgactaatt ttcatttatc ttccct
//
LOCUS       DAFLVO010000147         3816 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.152, whole genome shotgun sequence.
ACCESSION   DAFLVO010000147 DAFLVO010000000
VERSION     DAFLVO010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3816
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.152"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..357
                     /locus_tag="L1U99_002879"
     CDS             <1..357
                     /locus_tag="L1U99_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213376.1"
                     /translation="ILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFLM
                     SLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYIG
                     YFPNKNNNFYFYRNKL"
     gene            complement(483..1160)
                     /gene="nth"
                     /locus_tag="L1U99_002880"
     CDS             complement(483..1160)
                     /gene="nth"
                     /locus_tag="L1U99_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBN1213377.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(1167..1865)
                     /locus_tag="L1U99_002881"
     CDS             complement(1167..1865)
                     /locus_tag="L1U99_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBN1213378.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2133..3317
                     /locus_tag="L1U99_002882"
     CDS             2133..3317
                     /locus_tag="L1U99_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HBN1213379.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            complement(3323..3766)
                     /locus_tag="L1U99_002883"
     CDS             complement(3323..3766)
                     /locus_tag="L1U99_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1213380.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
BASE COUNT          977 a          756 c          631 g         1452 t
ORIGIN      
        1 atccttgcat ttattatttt ttctgtactt ttaagcacta ctcttaaagg aaaatttatg
       61 gaaagaagct ctcatgcaat gattctcact tttttatggt tgttgttcac cagaatctat
      121 atttttctga tgagcctgaa accgcccaaa tccattagtt tatgtttagt tataaatggt
      181 atttttttat tatcacttat catttttatt acacctttag atagatacgt cacttattta
      241 tataatcctt tggaatactg gacttatttt ataggtatat tggaaggcat tattttctac
      301 atcgggtatt ttcccaataa aaataacaac ttttattttt atcgcaataa attgtaataa
      361 gttaccatcc tagctactga gtatgtacat ttactttttc atgcaaaaaa gataaacgaa
      421 acagcttttc tccataataa caagataatt catacattta tttgcaatta aagaaaccac
      481 gtctacaggc gtggtttctt ttttagcgcc ttttctttta gacgcatccg atttttccca
      541 tcttgacata ttgatagcaa aggacatacc tcgcacttgg gatttcttgc cgtgcaatga
      601 tatctaccaa aaaaaatcag tgtatgatgt gtctttaccc ataattcttg tggtactttc
      661 cgcatcagtg tttcttctac ttccatgacc gtagcatcta gtttgcagat cctcaggcgt
      721 tttgagacac gttccacgtg ggtatctact gcgattgctg gtatcccgaa tgcatccccc
      781 aatacgacat ttgctgtctt tctgcctaca ccaggaagag acatcaattc ttctcttgac
      841 gttggcactt gcccatcgaa acgttcaatc agctgctgtg cacacgcttt gatgtttttt
      901 gctttatttc gatacaaacc aatcgttttt attttaagaa tgatttcatc gattgaagct
      961 tctgctaacg catcgggtgt cggaaaagag gcaaacaaat ctggcgttgc tttattcact
     1021 gatacatctg tcgcctgggc acttaagatc actgcaatca ataactcaaa tggattattg
     1081 tgcttgagtt ctccatgtgc ttcgggaaac attccataca tcgtttctag agcttccatt
     1141 gttttttgtt tgcttaacat attccgctac tcctccaacc aatttttcag tgagactttc
     1201 ggcaattctt cttgttgagc tgactgttct acttctcttt gaagaagctg ctgttttctt
     1261 cgtttttggt cttcttccac ttgttgtttt gtacgtagat tttttctttc ccacgatagc
     1321 aaaatgcggt caacgtaatt aaaactataa gcctgattta atacggcttc ccgcagtgct
     1381 agcttcaaaa tttccggctg ataatggtct tcttctagcc attgtccgat ccgctggaac
     1441 tcgatcgaag aaagcgggcg tccaaattct tgttcaaata attgatacac tgactggatt
     1501 tctttttctt gtgttttttc ttcgtatttt ttttcttgtg tttttaaata ctcacctaat
     1561 agatcataga tggggtaaag attatatcga tctgcttttt taccgttgac aatcgtcgtt
     1621 tctatcttga taaatccatt tgttacgaga cgatccagta tttgaaaaat ctgatcttgt
     1681 ttgattccca tatccatagc aatcatctgc aaatcaggga aagtatctcc ttcaagctgt
     1741 gccatatgca actgtagaac aaataaaaat tcttcagatt gtagaccgat cctatgataa
     1801 tttttaagta aaagattaga tatgactgtt tgtccagcgc ttaagtaatt ttctaaattc
     1861 aacatgattt ctcctccgct caatcacagt atacgtaaaa aaaacatggg aagcaagaac
     1921 aggtttcttt tctatttact tcactgatcg gtcagattta caatgtcgtc tacttgattt
     1981 ttgtttgttc atgtttttga tgcgtatctt cacttttcgg aataaataaa ttaagtagat
     2041 ttcgctgttc cttagaatgt tgacaaggaa acaaaattac tatacactat ttttgtttcc
     2101 aagttaacat tattgcataa aggagttttt acatgtacag tttcacaaat aaacattcta
     2161 aagtttttgg atacgtctct gtcttattca ctggattagg atttactatc gtcagtcctg
     2221 tacttccgtt tttaacgctg ccttattctc actccataca tcagcaagct ttctatatca
     2281 ctttgctcat gtctgtttat gctctagctg ccttcttatc tgcccccatt ctcggtagct
     2341 taagtgatca ttttgggcgt catccgatcc ttattatcag tttattagga tcaagtatcg
     2401 gatatttgct ttttggttta ggaaattcga tatggatgtt gttccttggt cgtatcattg
     2461 aaggattgac ggcaggagaa atctccacct tatatgctta ctttgccgac atcacggaac
     2521 ctaatgaaag aaccaaagtt tttggatgga tgggtgcttt agtcggtata ggaacaacgc
     2581 tgggtcctat tatagggggt ctattagctg agttggggaa ttctgttcct atatttattg
     2641 gagcactctt tactttctta aatgccgttt atggctacac atttatgcta gaaagccttc
     2701 caataaaaaa acgttcagta gatttaagtt tctcccatgt aagacctttt caccaattac
     2761 aacaattatt caagatttca tccgttattc ctttattgac agcaggtttt gctgtttggt
     2821 tggcagctgg ctctcttcaa tctatctttt ctcaattttc gattgacgcc tttcagtgga
     2881 aggctgggtt ggttggttta agcttctctt tgattggaat cttggatact gtctcgcaat
     2941 tgttcattat gcctcgattg ctcaaaaaat tttcagaaca gcagatcaca agaataggga
     3001 tgttcagtga aatcctcgcc tatctattca tcacattatc tggaattctt ctactgccga
     3061 ttttgttttt atttgggatt atctgttatg gtttcggtga ttctattttt actcctgtat
     3121 tcaatggcca actatccaat tctgtctcag ataaccagca aggtcttgta atgggcggta
     3181 cccaaagtat acaatctcta tcgcgcgtca tcggcccgct aatcgcagga cagctttatg
     3241 ctgcagcacc atttcttccg acggtattcg gatttttgct tatgattttt gcctattatc
     3301 actacaataa aaaatagtag cttcatttgc tacttcgtat aaattctctg tatcgaccga
     3361 taaaacgaaa tactgtgtca aattcttctt ttgacatatt ttcaaataca gtagcatctc
     3421 gctgtaccca tttttgatgg agttgctcgt gtctattcct tattttttgt ccgattggcg
     3481 tcaattgaaa atagatttct tttttattct cttcgctttg ataagtgttt atgatccctc
     3541 tagctatcag tttttttgtt agcttactga tggctcctct agtcatgtaa ctagcattcg
     3601 ctaattttgt cacgttagga tcagggattt tcccgatatg ttcaatcact tctagttcat
     3661 ttagagtaaa tcctgcaaat tctttttcca tttctggttt attacgatga ataatctcat
     3721 tagctaaatc cagatattct tctattagca gttgtctttt atccatttct acaccttctt
     3781 tttctttcat tatattgttt ttttgtttcc tattca
//
LOCUS       DAFLVO010000148         3768 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.153, whole genome shotgun sequence.
ACCESSION   DAFLVO010000148 DAFLVO010000000
VERSION     DAFLVO010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3768
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.153"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            127..579
                     /locus_tag="L1U99_002884"
     CDS             127..579
                     /locus_tag="L1U99_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213381.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            593..1282
                     /locus_tag="L1U99_002885"
     CDS             593..1282
                     /locus_tag="L1U99_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213382.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1407..3758
                     /locus_tag="L1U99_002886"
     CDS             1407..3758
                     /locus_tag="L1U99_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HBN1213383.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
BASE COUNT         1279 a          493 c          777 g         1219 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc aattatctta tcgtagatat atattataaa tttaataaga aagcgaggtg
      121 agaatcgtga aaaaaacgat actaagtatt ttttcagtat ttacaatatt aattgggggc
      181 tattttcttt tgaatttaga ttctgttaat tcaaacgctc aaataaaaga tcaaagagta
      241 gctgaacata ataataaaaa aatgagtttg accaaaaata tctattctat gtcagatgaa
      301 gaattgtata aagaatttgg tgatttatcc ggggaacagt tagaagaaag tattccagga
      361 attagtgact cagataaaat tgttgtcttg tctgctggtg ggcaattaat gggagatggc
      421 aaatccgaat tagttagtta taaacaaaat cacagacagt ttattgatgt taatactgat
      481 tccaacgcta tttcgattaa ggatctaaaa gagcttttaa atagtaaaag aaatgaatta
      541 aagcagataa aagaaactaa ttcagtggaa ttagagtaaa ggaagattca ttatgaaaaa
      601 gatttttggt gtttctgttg ggctacttat gatgttaaca tttggaaatg cagtatatgc
      661 tgctgagaaa gaagttattt cagatccaga gcagtacgcc tcacgatact ttgctgattt
      721 tgaagaagaa gataaagtac ttgcattgcc agaaggtggt tttttaaaag gggaagctaa
      781 aattgtatct atggataatc cagatataat tcaaggttca tataattcag aaactgatcc
      841 tgcttcagtt tcagtgacag aagcaaaaaa aattgttgct gaaaaattca aaaatgatat
      901 tgaaactact ccaattatgc ctcgaggagc atttccaccc gatgttggta ctagcggaca
      961 ccttcttgta ctagcaggag gaggaagcta taaatcacag ccatttagtg gtgcgggatg
     1021 gcgttttgga ggtatgggtg taaaaccagc tgatggtaca ggcaactttt tacgttggaa
     1081 atcctacatt gacgatggaa gagtaggaaa tgtaaatcaa gccaacgcaa ctaaatctgg
     1141 ttctattcaa ggaatggcat tgtatgctcg tgaaggattc aaatactttg caccaaacgg
     1201 gcctggttgg acaatgaata taggtattta ttacacttat aatcctgttg caggtacgta
     1261 ttatgttgtt caaaatattt aataaaacag cacaaagaga tttctttgtg ctgttttatt
     1321 atttttagtt gttgacaaac actaaaatat aaaatataat caacacataa acgaacgtat
     1381 gttcggcaag aaagcagggg atttttatgg atgagatggt tttaagtact cagaaatggc
     1441 taaacaagaa atacagtaat gttacagggt ttgataaggt tccagaaaat gggcgaacag
     1501 ggtggcctac aatctatgga cttattgaag gactacaagt agaacttggt attactaatc
     1561 tagtagctaa ttttggacct accactgaaa aaatgtacga taatcaggtt actcctaaat
     1621 ggggcaaaaa tctacctaaa aatattgtat ttcttattca aggtgccttt tggtgtaagg
     1681 ggattaatcc aggtggcttc gatggggtat atactccata tttagatact gctgtaaaag
     1741 agttgcagac tgatgcaggg tttaatggaa gcgctgtaac tggagttttg gatgcgaaat
     1801 gggccaaagc gttatttgat atgagtgctt ttgttcttgt tcccggcgga gatagtaaaa
     1861 ttagaaaaat gcagcaatgg ttaaatgtaa attatttaga atacacggga ataatgcctt
     1921 gtgatggtat ttatcaaaga aattcaaatc aagcattaat ttttgcatta caagctgaac
     1981 taggatattc tcccagtgaa gcaacagggt cttatggtaa tgggacaact agtaaaactt
     2041 atcctgtgtc tgaaggtaac tcgggaaact atgtaagaat aattcaatat ggattatatg
     2101 ttaatggtta ttttgaagac ggtacattcg atggtatttt cactaaatat atgggtttag
     2161 aagtactggc attccgaaaa tttatggtat tgcctgaata tactgaaata gcagatgttg
     2221 ttgtaataaa aggactattg tctagcgctg gagatattag aagatctgca gatggcgcag
     2281 atacttctac gcaattaact agatctcaaa tccaaacatt ggttgataat gatataaaaa
     2341 tagttggtag atatcttact ggtactgttg gaattggaaa agatgaacga aataagtatc
     2401 taactacaga ggaattgaat aatatttttt ctaaaaattt atctgtgttt cctatctatc
     2461 aagatggagg tgcagcatta gcttatttta cttatgatcg tggcttatca gatggtaaga
     2521 aggctataga tgcagcaaaa aatctaaata taccattaac aacagttatt tattttgctg
     2581 ttgatctaga catgttaggg gaagaaattc ttgcatatgc tggagaatat tttaaggggg
     2641 tatctgctgt aatgtcatat agcgggtatc aaacgggtgt ttacggaaca agaaatgttt
     2701 gttctcaaat aatcaataac gggtatgctt cgtttgcatt tgtttcagat atgtcgactg
     2761 gttatagtgg gaatttaggt tttcctatgc ctagacaatg gtcttttgat caatttgttg
     2821 aatttaccat aggaagtggc aacggagctg ttggtatcga tttaatcgct acatcgggta
     2881 gagatagcgg atttaatgag ttatcaaatg atactaataa tgataattac attgccaaat
     2941 acaatcagaa ggttataaat cagatggtac gtgcgtatca atatctatca caagctggtc
     3001 ttgataatcc ttggaaccct catttgacat tttatagata tgtaaattat tctggtttgt
     3061 catgggacat catttcttct cctgtaacag agcatgatag aaaaatttat gatgaatata
     3121 ggaataaatt aactaatagc gagggcctgt ataattattt tatagatcct aatactggtt
     3181 caataatagg tttgcctcac ttaattgtga cgttacaatc acagatgttt ctagccgaca
     3241 caatcaatga tagtgtttct gactttgcag gttggttagg agatttaatg acttgctggg
     3301 gtgaagttaa gaaattagga atacaaatgg agcaaggtgt atttgcatta gtaggtacgg
     3361 ctgcaggtgg aacatttagt ctagaagatt tataccaaga tgttgacgcg gtaaatgttt
     3421 ataccttagc aaaaagaaat tctgattcaa cagctttatc ggctttaaaa acgtactatt
     3481 gtgataaggg tgctattgat agatttaatc aatttgttaa gaacagattt ggttcttcag
     3541 ataaaatcgc ttcagtaaca aatagtttat tagaaaatga cgaaacagtt gatatcttag
     3601 gtgtagggat aatttcattt ttcattgata aaatagttaa taattcactt gggacagatt
     3661 ttacttatct tgattttatt ggagatgagg ggaaagttgc aaatggattt tctgaaaaaa
     3721 ttattcaatt tcaagaaaat agaagtaaac ttaattaaga atcgttta
//
LOCUS       DAFLVO010000149         3738 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.154, whole genome shotgun sequence.
ACCESSION   DAFLVO010000149 DAFLVO010000000
VERSION     DAFLVO010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.154"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            72..155
                     /locus_tag="L1U99_002887"
     CDS             72..155
                     /locus_tag="L1U99_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBN1213384.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            280..1017
                     /gene="erm(B)"
                     /locus_tag="L1U99_002888"
     CDS             280..1017
                     /gene="erm(B)"
                     /locus_tag="L1U99_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBN1213385.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1280..2143)
                     /locus_tag="L1U99_002889"
     CDS             complement(1280..2143)
                     /locus_tag="L1U99_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBN1213386.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2145..2417)
                     /locus_tag="L1U99_002890"
     CDS             complement(2145..2417)
                     /locus_tag="L1U99_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBN1213387.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2434..2643)
                     /locus_tag="L1U99_002891"
     CDS             complement(2434..2643)
                     /locus_tag="L1U99_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HBN1213388.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            complement(2742..3638)
                     /locus_tag="L1U99_002892"
     CDS             complement(2742..3638)
                     /locus_tag="L1U99_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBN1213389.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYF
                     KGGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKN
                     GNLASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMIERIIQLENEKE"
BASE COUNT         1148 a          654 c          579 g         1357 t
ORIGIN      
        1 aaattttgta taataggaat tgaagttaaa ttagatgcta aaaatttgta attaagaagg
       61 agggattcgt catgttggta ttccaaatgc gtaatgtaga taaaacatct accgttttga
      121 aacagactaa aaacagtgat tacgcagata aataaatacg ttagattaat tcctaccagt
      181 gactaatctt atgacttttt aaacagataa ctaaaattac aaacaaatcg tttaacttct
      241 gtatttattt atagatgtaa tcacttcagg agtgattaca tgaacaaaaa tataaaatat
      301 tctcaaaact ttttaacgag tgaaaaagta ctcaaccaaa taataaaaca attgaattta
      361 aaagaaaccg ataccgttta cgaaattgga acaggtaaag ggcatttaac gacgaaactg
      421 gctaaaataa gtaaacaggt aacgtctatt gaattagaca gtcatctatt caacttatcg
      481 tcagaaaaat taaaactgaa cactcgtgtc actttaattc accaagatat tctacagttt
      541 caattcccta acaaacagag gtataaaatt gttgggaata ttccttacca tttaagcaca
      601 caaattatta aaaaagtggt ttttgaaagc catgcgtctg acatctatct gattgttgaa
      661 gaaggattct acaagcgtac cttggatatt caccgaacac tagggttgct cttgcacact
      721 caagtctcga ttcagcaatt gcttaagctg ccagcggaat gctttcatcc taaaccaaaa
      781 gtaaacagtg tcttaataaa acttacccgc cataccacag atgttccaga taaatattgg
      841 aagctatata cgtactttgt ttcaaaatgg gtcaatcgag aatatcgtca actgtttact
      901 aaaaatcagt ttcatcaagc aatgaaacac gccaaagtaa acaatttaag taccgttact
      961 tatgagcaag tattgtctat ttttaatagt tatctattat ttaacgggag gaaataattc
     1021 tatgagtcgc ttttgtaaat ttggaaagtt acacgttact aaagggaatg tagataaatt
     1081 attaggtata gggcacctct aataactacc aattaattca cctcaaaatg aaattagaaa
     1141 aaaacagcga aatttttaaa tctatttctt atcgatacaa attcctcgta ggcgctcggg
     1201 accccaacat gaggaaatgt ttttataaaa aaagagtagt taccgttttt tggtaactac
     1261 tcttttcctt ttttaaggtt taaatacctg gaagtttagg tgttttgggt attggtggtg
     1321 taggtagctg caagctttcc attttttgtt gaattgcttt aaattcaggg gtttcttggt
     1381 gttgattttg aaccattttt tgctctattc tctccaaagt cggttgaatt tctttccctg
     1441 atactttacg atttaattct ctttctaagg tctctttcgg actaatggaa ggcgtttcta
     1501 agcttgaata gagtttcact ccttctctat tgtaaagcct tatatcgcta aataagcccg
     1561 ttttatgaag ggtttctaaa ttggtcggta agtttttgac aacaatatca tgcgcttgtt
     1621 ttggtgttgc cctagctgtc attggatcat ctgcatacat ggtttcatat cgttcaatcg
     1681 ttcctaagta tgattcaatt ttcggtactg ccatgacgta tatttttgtt tcataacctt
     1741 tagattgaag cattgtggct gtttgaatgg gaacgtctgt tgttcgtcct gttccttcaa
     1801 tcactaaatt atagccttga tcgcttaaac ggctaataag tgcttctgtc atgcgattcg
     1861 aataaggggt aacgtgtttt actacgtctt tttcatagag tttcactaat tcgtcaaaat
     1921 ttgggtgctg ttgtttaaag gtatcattat caatgacaat aacattccct tgtgtttctt
     1981 caaaaattgc tgatcgcaaa ctggttttcc ctgaccctgg ttgcccacca agtaaaaaag
     2041 cggttggcga ttcaaccgct agtctatttt tagttagtcg ttcaacattc ttttctaaac
     2101 gatcttcaaa ttgcttttcg gtgaagtcag taatattcgc catgttaagc cactttctct
     2161 ttattcaaaa tttgttttga atattgattc attgaccgcc aatactcatg aatagcttgt
     2221 aattcttcaa atggttgttg aaataaatca acttcttgtg ccacttctaa ttgatttaaa
     2281 agattcactt ctagtaaacg agtattttta gtatctagtt catgattcaa aacataattt
     2341 aatacccgat tataaacact tgccgataac tcattaatga tttcaatttc aaatgttttt
     2401 tcatacgtaa ctgccatttc attttcactc cttttaaagt ttgtcaggta aatatttccg
     2461 tatatattct tctaaggctt gatccataac ttcttttacg tttccgccat tctttgctgt
     2521 ttcgattttt atgatatggt gcaagtcggc acgaacacga accgtcttat cccccattat
     2581 atcttttttt gcgctgattg gcgtatcatt tcgttttgct ttctgtgcgc ctaaatttcc
     2641 cacgatcgct cacttctttc tatttcttct tactatttat tttatcatca cctatcacaa
     2701 atcacaagtg atttgtgatt aatcacttgt gatttgtgat tctattcttt ttcattttct
     2761 aattgaatga ttcgctcaat catttcaaaa aatacgttct catacataga caaaactttt
     2821 ttgtcatagc ctttgtgttc tgtaatgcca tttttagacc aagtacttac tttattactt
     2881 cgcttgataa tatttcggaa aaccaaatta tcctctttat gttctttgta cagttcttcc
     2941 aggtttgatt ttatcgttgc gctgtccgta tcaactaaat aaggaacaaa accaatcata
     3001 tctagtccag ggttaaactg ttcttgcaaa tcaatcaaat aggaaatata gttttgaatg
     3061 ttgtttgtac tttcttcttc tgcttgtaaa gggatcataa cgtaatcact cgccacgatt
     3121 gcattatttg tataaacgct tggcgttggt acagtatcaa taataataag atcatagtca
     3181 ctttttaaag gtgctaaaag agtagcaagc aatctacttt cattttcaaa cgtccatgag
     3241 cgagttaatt ttggcagtaa catcaaatca aacgtgccag ggatcaagtc taaattatca
     3301 gtcaaatgaa taatagaaga agccaagttt ccatttttca agccttcata aaaattgaca
     3361 cgtggcaatt ctacctcaaa agtttttgct aagtcttttg tcaatgttgc ctgtaagtcc
     3421 ttatcgatca ttaaaacttt taaattcaat ttgtctgtca agtaagcaaa catagtcgat
     3481 aatttggact ttccaacacc acctttaaag taattattca agataataat tgcttcattt
     3541 ttattgttta aaatacgtct taattcttca agtattttta gtttttcctt ctccataact
     3601 acgccccatt ctttttttgt atagtaatat tgtatcatta agaatcacaa atcacaagtg
     3661 atttgtgatt aatcacttgt gatttgtgat aagtgatttg tgattaatat ataaaagccc
     3721 tctttaaagg gcttttat
//
LOCUS       DAFLVO010000150         3689 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.155, whole genome shotgun sequence.
ACCESSION   DAFLVO010000150 DAFLVO010000000
VERSION     DAFLVO010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.155"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            11..478
                     /locus_tag="L1U99_002893"
     CDS             11..478
                     /locus_tag="L1U99_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213390.1"
                     /translation="MIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLFAWIVSVI
                     MIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVLRIAFYYT
                     LKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTMDL"
     gene            683..2347
                     /gene="alsS"
                     /locus_tag="L1U99_002894"
     CDS             683..2347
                     /gene="alsS"
                     /locus_tag="L1U99_002894"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HBN1213391.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            2360..3070
                     /gene="budA"
                     /locus_tag="L1U99_002895"
     CDS             2360..3070
                     /gene="budA"
                     /locus_tag="L1U99_002895"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HBN1213392.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            3200..>3689
                     /locus_tag="L1U99_002896"
     CDS             3200..>3689
                     /locus_tag="L1U99_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HBN1213393.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFI"
BASE COUNT         1203 a          591 c          801 g         1094 t
ORIGIN      
        1 ttgcatcgtg atgataggta tgacagaaga attagcaaaa gaaaaaagtt tttcaccagt
       61 acgtttgttc ataaagacgt ttcgccaatt ttggctaaag ggattttttt attggctatt
      121 tgcttggata gttagtgtga taatgatttt tgattgtttc ttttttatac gtttttctta
      181 tggaaaatgg ttgattccgt tgtttgtttt acttgcttgt ttatcagttt cctttagcat
      241 caactactgg tattttcagg tgagaaatcc agcgtcgaaa ccaaatcaag ttctacggat
      301 agcgttctac tatacgttga aaaaatggta tgtgagttta ctagattttt tactattgac
      361 aagtttgttt ctcttctttt tcgtaaagcc ccaatggtgt attctactag gtccttctat
      421 cgtatttggt ttgatttact tcaacaatcg taaattgatg agaactatgg atctgtagac
      481 tttataaatt gaaactttca attaagaatg acagttttta tgtaaaaact gtcattcttt
      541 ttcatttttt gaaacatatg gctaaacaaa tgaaataaaa cgtgctatac ttttgaatga
      601 aacaggttta gaaactgtat caattatttg tgattatttc taactaataa ttaaaaataa
      661 agcataaaaa ggacgatgtt caatggacga aaaaatgaaa caaggttcga aatctgtagt
      721 agaaagtttg attaatcatc atgttgatta tgtattcggt ataccaggtg caaaaatcga
      781 tggtgtattt aatgaattag aggatcaagg tcctgaatta atcgtgactc gtcacgaaca
      841 aaatgctgca tttatggcac aagcaatcgg acgtattaca ggagagccag gagtagttat
      901 cgcaacaagt ggtcctggtg ctagtaactt agctacaggt ttggtaacag cgacagcaga
      961 aggtgaccca gttttagcaa ttgccggaca agtaaaacga agcgatctat tgaagttgac
     1021 ccatcaaagc atggataatg cagcactgtt ccagccaatc acaaaataca gtgcagaaat
     1081 ccaagatcca gaaacaattt cagaagtgat tgccaatgct tatcgtatgg ctaagagttc
     1141 aaaaaaaggc gcgagcttta tcagtatccc gcaagatgta gtggatgcac ctgtccaagg
     1201 gaatgtcatc aagccattga gcgatcctaa attaggttct gcttctgcag atgatatccg
     1261 ttacctagct gaacgcatta gagaagcaaa actaccggta ctattagtag gtatgcgagg
     1321 atcaagtgaa aaagaaacgt tagccatcag gcaattagtt ggaaagacag cattgcctgt
     1381 tgtagagaca ttccaagcag ctggagtgat ctcacgtgaa ttagaagcgc atttctttgg
     1441 tcgtgtgggt ttatttagaa accaaccagg agatatgctt ttgaaacgaa gtgatctagt
     1501 tattgctatt ggctatgatc caatcgaata tgaagcaaga aactggaatg cggaaaaaga
     1561 tgcgcggatc attgtgatcg atgaagcgcc agctgaaatc gatcctttta tgcagcctga
     1621 aagagaattg atcggtgata tctcagccac tcttgattta ttgacaggtt cattagagcc
     1681 tcaacaagtg tcagaagatg caaaagaata tttagcatct cttcaagcag aattaacgga
     1741 gcgggacatt gttcaatcaa aaggagaagc aggtatcttg catcctttag aagttattaa
     1801 cacgcttcag tcaaaagtaa cagatgatat gactgttacc gtagatgtag gtagtcatta
     1861 tatttggatg gcacgccact ttagaagtta tgaacctcgt catttgttat tcagtaatgg
     1921 tatgcaaacg cttggtgttg cattgccatg ggcgatttct gctgcattgg tgcgtccaaa
     1981 tacacaaatc gtatcagttt ccggcgatgg gggattttta ttctctgccc aggatttaga
     2041 aacggcggta cgtaaaaaat tgaatatcgt tcatttgatt tggaatgatg gacactacaa
     2101 tatggtagag ttccaagaaa aaatgaaata tcagcgggcg tcaggtgtag actttggtcc
     2161 agttgatttt gtgaaatatg cagaagcttt tggcgctaaa ggaatccgag ctacaagtgt
     2221 agaggaatta gaaaaagctt tagaagaagg atttgcgaca gaaggacccg taattattga
     2281 tattccgatt gattaccgtg ataatgagaa attgggagaa acaatcttac cagatcaatt
     2341 ctattaagga agtgtcgaca tgactgaaaa aatcttatac cagcacggga cattaggagc
     2401 tttgatggct ggcttgatgg atggaacaga aacgattgct catatattag aaaaaggaac
     2461 tctgggattg ggaacattgc atgggcttga tggtgaagtc atctttttag atggcgtagc
     2521 ttatcaagga agatcagatg gctcagttgc ccaattagat ggaagtgaac ttacccccta
     2581 tgcagcaatt acagatttta cgccagatac tagtttttct gtctcaaaaa ctgcagatgg
     2641 agaacaattg aaaaaagaca tattagtaag agaagccggg gaaaacctat ttttggcagt
     2701 gaagataact ggattattca aaaatatgca catccgtatc atgccgaagc aagaaaaacc
     2761 ttacagaaga ctagcaaaaa tttcagagtc tcaaccagaa ttccaacaaa gcaatgtcca
     2821 aggaacatta gtcgggttct ttacgcctga attattccaa ggagttgctg cagcgggatt
     2881 tcacttgcat tttatcgatg atacacatac atttggcgga catgtaatgg attttgaagt
     2941 ggctgaagga aaagttgaga ttagccgcat ctcgtccctt gtacagcatt ttccagttga
     3001 tgatccgact tttgttcacg aaacgattga ttatgctgat ttagcagcag aaatccaaca
     3061 agcagaatag aaaaagacag cgagatgcgt tcaaggtgat taacctgacg tatctcgttt
     3121 ttttgaggag gaaacctagc gtttacaaaa aaactgagct ataatcttct ccatagatca
     3181 aaaaggagcg gtttttatca tgtggacaga aaaacagaaa aaagatgcat acgaaatttt
     3241 attattacag caacaaggat tattagaagc agaagataac tggttagcaa atttagcaaa
     3301 ttcatctgca ttgttgaatg agactttgcc tgagactgtc tttgcaggat attatttatt
     3361 cgatggtaat gaattgattt taggaccgtt ccaagggcga gtttcttgca cacgtatcaa
     3421 gatgggaaaa ggagtttgtg gagaatcagc tgaaaaacaa gaaacattga tcgttgatga
     3481 tgtcaaaacc catgcaaatt acatttcctg cgattcagcc gcacaatcag aaatcgtagt
     3541 gccaatggta aaagaaggta atttaatcgg tgttttagat atcgattgcg gagtaacgaa
     3601 agggtatgat gaaatcgatc aagcatttct agaaaaatat gtagatcttt tattagcaaa
     3661 ttttaatata aatgcttttt catttatta
//
LOCUS       DAFLVO010000151         3660 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.156, whole genome shotgun sequence.
ACCESSION   DAFLVO010000151 DAFLVO010000000
VERSION     DAFLVO010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3660
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.156"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(378..1082)
                     /locus_tag="L1U99_002897"
     CDS             complement(378..1082)
                     /locus_tag="L1U99_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213394.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(1269..1514)
                     /locus_tag="L1U99_002898"
     CDS             complement(1269..1514)
                     /locus_tag="L1U99_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213395.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(1531..2382)
                     /locus_tag="L1U99_002899"
     CDS             complement(1531..2382)
                     /locus_tag="L1U99_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBN1213396.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            2548..3552
                     /locus_tag="L1U99_002900"
     CDS             2548..3552
                     /locus_tag="L1U99_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBN1213397.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
BASE COUNT         1145 a          623 c          708 g         1184 t
ORIGIN      
        1 ggtcgactaa attttaccaa aagtgagtct ctttttgagt tgaaacgaag aaaaaagtgt
       61 tggtagaaaa tcgctttcga ttttccacca acacaaaata ttatagaacc gcttttttct
      121 ctatcagaaa atatgtttat tattagaatt ttttatagtt aaggttaggc atcttaagaa
      181 atcaggcaac tccaagatat cttcaggtag aagagaagtc gcctaacatt gtaggatcat
      241 aggtgatttg ttggacaggt caagctgata tttgagcctg atgttagaag gaatttcttt
      301 ttacttgctg tagaaattat tatatgacta aaaaggctgg gattttaaat cccagccttt
      361 tatgacaaat agaattttta tcgatcagta atcgctgtcg ctgcaaattg ttcgatcaaa
      421 ggaatcaaag tcaatttgac tttgtatttc cgttcgagtg ctttttcgat aacgaactca
      481 ttttcagtag tcatagaaat agttgctaat ttacgaggtt catcagcatt tttttcatta
      541 ataactactt catgttcatt ttgttctgtg taaaatttag gatactcagc aacggctttt
      601 gaaaaatcag caaaacttaa agcggcattc gtatcagttg agcgtgtatt ttcagttgtg
      661 tccgcttttg gtttttccgt tttttcttct ggcacactga ctgtttcttc tgtaactggt
      721 gtcgcaacag cttgcgcagt tggttcatcg tttttcaatc gttgatcatt ccagtaagac
      781 acgatttcaa taagaagatt gtcacggaat cgttcgaaaa tcccgttttc tcctgaacga
      841 attctcttta atacagtatt gaagttgtca tcgattggca cgttgatccg tgtatcttca
      901 tttgttttcc cagctaatcc gatcgttaag atttgacggt ttttgggatc aagcatgact
      961 tgtaacggca aaccataacg tcgcaagctc tcttcttcta gagaacggaa taattgtcct
     1021 cttacaccat ccaatgaagg acggaattga tttaataatt tttgtttctg ttttttcttc
     1081 atatgttctc tccttcgctc ataccctttc gattataaga aaaaaacagc caaatgaaaa
     1141 ggagtaatgc aaaaaaactt gcgtatacgc aaattacaac agaaaaattt gcgtattttc
     1201 ccgttttttg aaagaaaaat aaaaaatgga acggattatg tatatataca taatccgttc
     1261 cattctttct attttttcgg tatcaaggca aaaacaggta gttcaggtga ataaatgact
     1321 tcatgttcgt gccagggttt gaccattagc gaatgatcga accgtttttt cagttcttcg
     1381 atgatttgat catgtgtcca gtttcttgca ggaaaatgtt ggattttctc tgcatcgatc
     1441 aaaaagacaa aatcggaatg aaaagtctgg gtaacttctt ccgagagaga attcaagcgt
     1501 tcgattggat ccataaaatc acctttcgac ttaaaattgg gtagtatctg ggtcttttgc
     1561 tttgccgact acaccatcta actgatcgat ttgtttcatt tcttcttctg ttaattcaaa
     1621 atcaaataat tcagtatttt ctttgattct gcttggtgtc actgacttag gaagaggaag
     1681 gaattcgtgt tgcagcgacc aacgcaaagc aacttgtgca atcgtcttgt catgtgcttc
     1741 agcgatttgt ttcatttcag gcacatcgaa gattttacca gtgcctaatg gactatatgc
     1801 ttcgaggatc atatcatgtt tttttgcata ctcaactaca gttgtctgta attcgcctgg
     1861 tgcaaggaaa acttgattga ccatcggcat aatttttgct gtttttgcta gtgtatctag
     1921 atggtggggt aagaaattgc tcacaccgat tgctttgatt ttacctgctt catacagttc
     1981 ttcaaatgct cgccatgtat ctgcatttgc ttgttcccaa ttatcacgaa aagcaacagg
     2041 gtttggccag tggatcaaaa acagatctaa ataatctgtt tggagcttct tcaatgattc
     2101 ttcaaaagaa gacatcacaa gttcatagct gtggtttgca ttccataatt ttgttgtcaa
     2161 gaatatctct tctctaggaa ttccactttc cttaatcgct tggccgacgc tttcttcatt
     2221 cttgtatcct tgggcagtat cgatatggcg ataacctgca gccagcgctt ctttaacaga
     2281 ggaaacagcg acatccccat caggtgtttg ccatgtgccg aatcctacta ccgggatttc
     2341 gtaaccattt gatagacgat aagtgcttgt taatgaattc atactttcag ctcctttttt
     2401 attcgttcaa ctataagtgt agcgcatttt tcgaaaaaaa gaatccattt tgtttctact
     2461 cttgaaattt ttgtttaaaa gaaaatgatt ttgattctgg tatttttgat tttttttccg
     2521 taaactaaga cagaagggaa tgagaaaatg gatatctatt taaaaaaagc aattctgcat
     2581 attattgaca gagaaactgg ttctccagtc ttttcacaaa aagagctgga tctgacaaaa
     2641 gaatatattc gtgattttct tcaaaagaag atccaaaaaa tctcttctgc tcaaacaaaa
     2701 actggacaac tagcagaaga aagcatgatc gttgaatcac ttaaaatcgc tcaagaaaat
     2761 tttgtggaag caagtgaagc aatcgttcag cggtggttcg atatctacca agaaagtgaa
     2821 gaagcaccta gtgcagatgt atttgttgtc ttgtatgaat tagatacagt gatgtactta
     2881 tctttattga aagtcaatta tcgtgaggct tacactcact ttgttgaagc agacgaagca
     2941 gggatcgaca accgcttgat tttgaatcga gcaattctag gggcgaaaac acaaaaagca
     3001 gatgaagcat tcgctgtgaa tttgactgat tggacctacg aattaattga aaaaaaatat
     3061 gagttttctg gcaaaaaaga gctttatttt tctggaagag tgatcgaaag tgttcctgca
     3121 ccttctttag aagaaaatgt aaaagtgatc caaaaagtag ccaagcatct tggaaaaaaa
     3181 tttgagacag aagaatttga tatcatggct gatttgaaag aagctgtcta tgatacgata
     3241 gaagaaaaag gtcggttgga tcatgagatg attgcggaaa aagtcttcaa ggaaaacatc
     3301 acggcaaaaa tggcttttaa agaagaagta caagagcaag gatttgtccc agaagcacct
     3361 cctgtaaaag aagtacaaga aatttctgag aaaaaatttg gaaaacaaaa attcaagcta
     3421 tcaaacggga tcgaactgat cgtaccagta gatgtatatc gcaacccaga tttgattgaa
     3481 tttgtgaata atccggatgg tacgatatcc gtgatgatca aaaatgtgga tgaagtattg
     3541 aatcgtttat aaaaatgact agaatattag gtgttcaagt accagtgatc agttaaatga
     3601 attgtgtcaa gagaaggatc ggaaaagacg aatataacaa aaaaagagcg tgagacaaaa
//
LOCUS       DAFLVO010000152         3646 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.157, whole genome shotgun sequence.
ACCESSION   DAFLVO010000152 DAFLVO010000000
VERSION     DAFLVO010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3646
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.157"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            61..282
                     /locus_tag="L1U99_002901"
     CDS             61..282
                     /locus_tag="L1U99_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HBN1213398.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKELMKEHEENDQSISHEDMLKELGL"
     gene            284..550
                     /locus_tag="L1U99_002902"
     CDS             284..550
                     /locus_tag="L1U99_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBN1213399.1"
                     /translation="MTYQVRYEREAQKALKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            663..1202
                     /locus_tag="L1U99_002903"
     CDS             663..1202
                     /locus_tag="L1U99_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213400.1"
                     /translation="MYNISVNKLINFQKERFFMGWYGAYSSANEVIEEKKGYAKNGLE
                     IVDTKVTKTYGIILFKDAEGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFF
                     VGDQEKMVKQQLDRIKEENNKPNLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQ
                     DGSLTRFTRLSAGDVKEVA"
     gene            1696..1980
                     /locus_tag="L1U99_002904"
     CDS             1696..1980
                     /locus_tag="L1U99_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213401.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGVVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKNSFIGKLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            2254..2508
                     /locus_tag="L1U99_002905"
     CDS             2254..2508
                     /locus_tag="L1U99_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213402.1"
                     /translation="MNYTDEEQITLEYVFTNEKGEEIEKVLIISSKDLENALTYEPYE
                     STVTVNEFLDTYTSNDTWEIMNICNANNIQFAEKTNKSFY"
     gene            2590..2775
                     /locus_tag="L1U99_002906"
     CDS             2590..2775
                     /locus_tag="L1U99_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HBN1213403.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            2842..3237
                     /locus_tag="L1U99_002907"
     CDS             2842..3237
                     /locus_tag="L1U99_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HBN1213404.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEDLLEK"
     gene            3227..3604
                     /locus_tag="L1U99_002908"
     CDS             3227..3604
                     /locus_tag="L1U99_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213405.1"
                     /translation="MKSKKETEPMKSTHLNYFSRTLINNLLKDTTGISVSTKHFANDL
                     IIFEDNNLRIEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKK
                     AKLLFEFQTDYHNELLAQSEILD"
BASE COUNT         1322 a          602 c          662 g         1060 t
ORIGIN      
        1 taactattgc atttgtcata caatcgtagt acaatgtaat tgaaaaggag ttgataaact
       61 atgccagtaa taagtattcg tgtatctaaa gaagaaaaag attttcttga aaaagttgct
      121 gaattcaacg gagataacat ttctgaattt atgcgtagta attccctgca aacagcagaa
      181 acgttagtag actttgccac ctacaaggaa ctaatgaaag agcatgagga aaacgatcaa
      241 agtatttccc acgaagatat gctaaaagag ttaggcttat aagatgactt accaagtaag
      301 atatgaacgt gaagctcaaa aagcgctaaa aaaaatggat aagtttcagg caaaggttat
      361 cctaaactgg atcgagaaaa atcttgtagg cactgatgat ccaagaaaac atggtaaagg
      421 tctaacagct aataaatcag gctactggcg atatagggta ggtgcctacc gtataatagc
      481 tgatattagc gagcatgaag tgacaattct tatattgtct attggtcaca gaagtgaagt
      541 ttataagtaa cagacaagct gataaggctt gtctgttttt ttgttaaccc aacaaaatca
      601 ctgtttacga tcccacttta cctaaaaaag aacaataccc tcttgttatt atacacactg
      661 gtgtgtataa tataagtgta aacaagctaa ttaactttca aaaggagcga ttttttatgg
      721 gatggtatgg tgcttattca tcagcaaatg aagtgatcga agaaaagaaa gggtacgcca
      781 aaaatggttt ggaaatcgta gataccaaag taacgaagac ctatggtatt atccttttca
      841 aagatgcaga aggaacctac gatattgaca gcttcatctt tcgagatgaa atgtacaaac
      901 caatctactt cttaaatgac agtcctgctt actttaagaa aattccgaaa aaatggttga
      961 aattctttgt cggtgatcaa gaaaaaatgg ttaagcaaca actagataga attaaagaag
     1021 aaaacaataa accaaacctt gatgacttat tagttgcagg taaaacttac tcaatctggg
     1081 atggatcgta tgtcgctgtt tatcagtata aactcaaacg tagctttatt tttagactac
     1141 aagatggatc actcactcgg ttcactcgac tatcagcagg agatgttaag gaagtagcct
     1201 aaaacttaaa tacataaaca taaacgtgta tacgtttatg tttatgttta tgtatatgta
     1261 tatgaatata aacgtattag gtacgaacgt ttttaaatgc ttttctgggc tttgatttta
     1321 gggtagggct aaaacatcca ttgatccaaa acagctcaga aacgcattta aacgtatctg
     1381 ataccaatat tacagaagga gtgtatcgta tgattaacct atttctttta gtgacagcta
     1441 gtacattatt ctttactgga atatcactga taatttccta tttgatctat aagaaagccg
     1501 aaacttacac aagcaaagca accggactag ccgtttcctc ctttttaact ttgctgactt
     1561 tttttgttac tctatcgttt tcttttgttt agcacagctg atccatcagc aaaaaacctc
     1621 tctttacatt atacacacta gtgtgtataa tgtaattgta aacaagctaa ttaactttta
     1681 ggaaggagtg acaatatgct aacagctaca ttacagcaac ctactcacgt tgctattgca
     1741 gaaagctata caattaatgc aggggtcgtt aaacagctga tcaaggatcg agaattcaaa
     1801 aagtttaaca gtcgtcaagc gtataacaga cagttaaaga aagctattct aaagcacaaa
     1861 aattccttca tagggaaatt ggaaagtgtg gatgttaaaa ctgtttcaac ggcattttca
     1921 gttgttgaag tgactattga cggtcgcttg atttctctat ttgcttttgg aattaattga
     1981 tagggagtgt ggactttgga aggtaagact tttgcagaaa tttggactga atttattgag
     2041 gtaccaactc gcattgatcc gataacttct gaaaaggtat tggatgcaga cttctacaat
     2101 ctcaaagcag gtactagcct tgaatgcgtt tagatgtatt tagaagagca tttcaaaggc
     2161 gtaacgctcg gtcacgtctt ataccacaat ggtgccgagt gggatgcaat tggaaatatc
     2221 catttttctt aatacaagaa aggagaacac aatatgaatt ataccgatga agaacaaatc
     2281 actttggaat acgttttcac aaatgaaaaa ggggaggaaa ttgaaaaagt cttgatcatt
     2341 tcatcaaaag acttggagaa cgctttgact tatgaaccat acgaatcaac cgtaactgtc
     2401 aatgaattct tagataccta tacttctaat gatacttggg aaattatgaa tatttgcaac
     2461 gctaataaca ttcaatttgc tgaaaaaacc aataaatcat tttattagtt ttgcaataaa
     2521 acatcctctt tttctattga ttccatacac aacaatgtgt ataatagatt ttgtaaaggg
     2581 agggtagcta tgcctaagac agcaagagaa attgtaaaaa ttctcaaatc taacggcttc
     2641 aaaaagactg gacaaactgg cagtcatgca aaattttata attccaagac taaaagaacg
     2701 gtcgttgttc cgatccacaa tggtgatgta ccactaggaa cagaagctaa tatctggaag
     2761 caagcagggc tttaacagcc ttgccttcct atttggtatt aggcatacta tcctctctta
     2821 cactagaaaa ggagcgagga aatgaagaca aaaaatattt tttatccggc aatcttcgag
     2881 aaagaaggag aagcttataa catcgttttc cctgacttac cggaaatatc tacctttgga
     2941 aatagtcttg aagaagcata tttaaacgct aaggatgctt taggattagc gctatatagt
     3001 gtaccagatg cagaatttcc taaaccatca gcagtggaag aattaacttt gaaagccaat
     3061 caagtagtag taatcatcca actaaacatt aaacttttcc gaagaagctt aaatacaaaa
     3121 acaattagaa aaaatgttag tgttccggaa tggttagttc ttttagggaa ggagaaaaac
     3181 ataaacttct ctcaattact tcaaaaagca ctagaagaag acttgcttga aaagtaaaaa
     3241 ggagaccgaa cctatgaaat ctacacactt aaactatttc tctcgaacgt taatcaataa
     3301 tctattaaaa gatacaactg gcattagcgt tagtaccaaa cactttgcca atgatctaat
     3361 tatttttgag gataataact tgcgaattga gatgtttatt gaacaggcaa ctcctaactc
     3421 aatacctgaa ttctgctata cgcacactga aaaaatgaaa catgcaaaat cagttaaaga
     3481 tgttgaagca ttaagtgaat cactaacgaa cgctttaaac ctcgttaaga aggctaaatt
     3541 gttatttgaa tttcaaaccg actaccacaa tgagttgctt gctcaatctg aaattttaga
     3601 ttaattgaaa caggagaaga gaaagatgaa acaaacacaa acagaa
//
LOCUS       DAFLVO010000153         3602 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.158, whole genome shotgun sequence.
ACCESSION   DAFLVO010000153 DAFLVO010000000
VERSION     DAFLVO010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3602
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.158"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            186..2855
                     /locus_tag="L1U99_002909"
     CDS             186..2855
                     /locus_tag="L1U99_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HBN1213406.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2946..3566)
                     /locus_tag="L1U99_002910"
     CDS             complement(2946..3566)
                     /locus_tag="L1U99_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1213407.1"
                     /translation="MFLINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKA
                     MHMVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPG
                     IEKRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTI
                     IKITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
BASE COUNT         1062 a          660 c          673 g         1207 t
ORIGIN      
        1 atttttaagg gtgggacttt tgattcctac cctttttttg cgtttatttt tgttatacga
       61 acaaattatg aagttattta ttctaaattt tatttttttg tgaaaattag actcttttta
      121 agcagagaaa aacaaggata tgataaactg aatacaactt catagaaatt tggtggaaaa
      181 taaatatgaa aaaaaattta aagtcattct ttagagaaaa cggacgctac gcagcagcta
      241 gtttcctgat tccgtttttg attttagcac ttgtttatct aagtatcggg atctatcctg
      301 gaagcagcag aagtattttg gcaagtgatg ccttttcaca gttttctaat tttcatgcca
      361 gcttccgaaa tgttcttctt ggaaagcaaa gtatttttta tacatggaat gcttctctag
      421 gattgaatta tttatcttta atttcttact atctaggcgg gatcttcacg ccactggtgt
      481 tcttttttcc aaaccagatg atgccagatg cactgtatgt tctgactttg cttaaggtcg
      541 gctgtgccgg attggctttt tggtttcttg cacgtacgtt caagattcct cgctgggggc
      601 atgttgcact tagcgtcagt tacgcattga tctcatttat cactgcacat tcggagatca
      661 tcatgtggct ggatgcattt gtttatcttc cattagtgat tttggggatt catcgtgtta
      721 tggatcttaa acggccgaaa cttttattta tcagttattt actcttgttt ttatccagtt
      781 tttatatggg ttttatgatt ggcgtatttt ctttcttata ttttatcgcc cgtctattga
      841 caaactggtc agaatataaa aaaacgattg ttccttatgg tatcacttct ttactggcag
      901 gcggcgcttc aatgatcatt gtattgccag cagtgctgga tcttcggtca aatggcgagg
      961 cactgagtca gatcactacg ttgaaaacag aagcgacttc ttatctggat ctaatcatga
     1021 aaaatatgat tggtgtttat gacacgacaa aatacggatc gattccgttc gtttacgcag
     1081 gtctgctacc attagtcctc tgtctgtttt attttgccag tcggaaagta ccgttgaaaa
     1141 ataaattttt gtacggcagt cttttcgcca tacttatcgc aagtttctat cttgttccat
     1201 tgaatttgtt ctggcatggt atgcatgcac cgaatatgtt tttattccgt tatgcctatc
     1261 tgttctcttt cttagtgctc ctgcttgcag gaaaaggatg ggaaaagata gaacaagacg
     1321 atcgtgggct gttgttagga atcattttgg tcgtagctgc tctctttgcg gtggcatggg
     1381 gcatcaaacc tgaaggaagc tacacctatg tgacgatgac ttcctttgta ttgacagtgg
     1441 ttttcttagg gatttatgct tttgctgtgg gattttatca gcataaaaaa ctttcattca
     1501 atcatctgag tatattgtta ttattgatca tgtctgctga agcactggtc aatacgaaca
     1561 gtatgatcca tggcattctt gatgattgga attatgcttc ccgcagttta tatactgatc
     1621 cttatcctga cttgaaagct cttgtaaatg aaacaaaaaa agattccgac tcgttttacc
     1681 gcttggaaaa tctggatcca gtatctgcaa acgattcgat caactatggt tacagtggta
     1741 tcagtttgtt ttcttctata agaaatcgta attcttcctc ttacctggat aaattaggtt
     1801 tccgttcaag agggacaaat ttgaatatcc gttataacaa taatactttg ctaatggatg
     1861 ggtttacagg aatcaaatat aacatttcta aaaacgaaag cacgttcagt aaatatggct
     1921 tccgccaagc tggtcaaagt ggcgactata cactgtatca gaatgtcaat gcattgccac
     1981 tagcatttac tgcaccgttg tccgttaatg atgttgagca gccagtgaca gataatttga
     2041 ccagtcagac aaacttgatc aatacattgt ctggtttaaa tgaacagtat tttacattct
     2101 atacacctac tttgaagaat cagttgaata cgacgatcac aaagacaacg actggcgtca
     2161 cttactcaga aacagcagat aaccagccaa aagagctcac ttgggaagtc catgtgcctg
     2221 caaatacaca agcttactta agtttgttcc caaccaattt tgcacaatta gaaagttcta
     2281 gtgcgacgat cactgtcaat ggtacatcgc gaaaaacgca aatcaacatt tctggtcaat
     2341 actatgatct tggctattat cctcaagaga caacagtgac atttactgca agtttttatg
     2401 gaacgaaaga agtaagtttc atggagccta aagtcgttgg tctagatgtt gtagcctatc
     2461 aagccgcaat gaatcagatc aaagaaaaag gtgtcgaaat ggaagccact ggcagaaaag
     2521 cttctgggac tgtaaatacc gctgaagatt ccatgttggt gacaactatt ccttatgaca
     2581 aaggatggaa agctaaaatt gatgggaaac cagtcaaggt cagcaatttc aaagacgcat
     2641 tcttgatgat aaaagttcca gcaggtaaac atactgtcac tttcagttac ttgcctgaag
     2701 gatttacgat aggtgcaatc ctttttgtcc tatgtattgc attgtttatt ctttatgtct
     2761 ggtaccttga ccgcaatcgc cccttttatg gcacgattga tccagcaata gaagaaaaac
     2821 cgcgaaatac acacagaaga agacgaagaa aataaagaaa cgatggaatc tgtgtcactc
     2881 ttctatttaa atggcaaaaa tttcaatctt taaatgacaa aaaccacctg atttttggtg
     2941 gttttttata tacctatgac taaactatct cttgctgctt cgacaacttc tacagtgatc
     3001 ttatccattt gattgattct taaaatccga tcaatctgcg caaataaacg atgaataagc
     3061 ctaaaatttc cttttgtgat cttaatgata gttgtgatag cctcataatc agaaaaatct
     3121 tctagcttga tatcaattcc taaatctgcc catttgtatt ccaaaatatg atgtgtttcg
     3181 tccttactaa ggttatcaaa ttcatgtgca aatcctatgc gagagtaaag ctgcggataa
     3241 cgagacaatc ttttttcaat accaggcata ccgataagaa ccattgccag atcatttcta
     3301 tcgtaaatat ctcttagctg ttctaaatgc tgaagcttta aacgatcaat ttcatcgaca
     3361 ataattaagt caattgcttc ataggtttta ggcacaggag gatcttcttg attgtatttt
     3421 agtaccatat gcattgcttt agtcagacct attctactag ttattgtgtt aatatccgaa
     3481 ctgacacgag acatcttttc agctggtaca gtataaaaaa ctttatttac acttaatatt
     3541 tcatctgttg catttatcaa gaacaagaaa aagtctgaat attcaaaaaa aataacggtg
     3601 ta
//
LOCUS       DAFLVO010000154         3560 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.159, whole genome shotgun sequence.
ACCESSION   DAFLVO010000154 DAFLVO010000000
VERSION     DAFLVO010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3560
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.159"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(114..187)
                     /locus_tag="L1U99_002911"
     tRNA            complement(114..187)
                     /locus_tag="L1U99_002911"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(151..153),aa:Ile,seq:cat)
     gene            complement(376..1395)
                     /locus_tag="L1U99_002912"
     CDS             complement(376..1395)
                     /locus_tag="L1U99_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HBN1213408.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RADVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            complement(1392..1616)
                     /locus_tag="L1U99_002913"
     CDS             complement(1392..1616)
                     /locus_tag="L1U99_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBN1213409.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            complement(1613..1906)
                     /locus_tag="L1U99_002914"
     CDS             complement(1613..1906)
                     /locus_tag="L1U99_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213410.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            complement(1943..2080)
                     /locus_tag="L1U99_002915"
     CDS             complement(1943..2080)
                     /locus_tag="L1U99_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBN1213411.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITDEEADKIINKDKSA
                     S"
     gene            complement(2082..2513)
                     /locus_tag="L1U99_002916"
     CDS             complement(2082..2513)
                     /locus_tag="L1U99_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213412.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            complement(2527..3021)
                     /locus_tag="L1U99_002917"
     CDS             complement(2527..3021)
                     /locus_tag="L1U99_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213413.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            complement(3021..3470)
                     /locus_tag="L1U99_002918"
     CDS             complement(3021..3470)
                     /locus_tag="L1U99_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213414.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKVKLDGLANITFEKVGTV"
BASE COUNT          979 a          744 c          585 g         1252 t
ORIGIN      
        1 ataaaaggat acataaaaaa gccactcatt tgagtggcaa tgaagaaaag ctttagcttg
       61 tataatactc ttcaaaaaat tctaacacag aacgattcaa atggctacgt taatgtaccc
      121 tgtaggactc gaacctacga ccggacggtt atgagccgtc tgctctgacc aactgagcta
      181 agggtactgg ttgttgccac ataaagccat aaacaatcaa ccagtagaat gtgtggcaac
      241 aaacctgtta tcgcatagct tggagtgtga ctattatggg tgatagtgaa gatatgcgat
      301 aacatcacta ttttatcgaa tgatttttat agttgtcaat atagttatgt aatgctcctc
      361 aacgaggagc tatttttatc gtttaggaat atttaaatac caacgtttgt catggaaatc
      421 ttgcgcaccg cctttagtgt ttccctctgg atcattcgtt gcccgcatca tgacatagac
      481 tttcttatta gggaagttac gcatgttaaa agatacatga tagccaacat ttccagaagt
      541 attataagct tgatttacat ctgctctata aattccatca gctcttactc gagctaattc
      601 tttcccagta ttgtaatcca taatgaagat atactcgtat ttatagttag caatgtgcca
      661 tccagctaca tgcaaatttg cattttcgat ttctccaaac tgatcaatgt gggcgtaatt
      721 cgttccatct gtcagtgtag gattagctgc accagctcgt gttggatcaa tgacaggctt
      781 gttttcagaa gttgttggat tttcatcggt aaatccatga gctaaatcat atgctaattt
      841 ttctttactt acgcccattt cagaaagata accgtaagga tctgtatgat cgccccagat
      901 gttttgtgtt acccataaat gcgatttgat tcccggttgg ttataaggag tgtccaacgt
      961 taatggaata ccatatttca ttgctgaatc tctagccaat tcaacgtatg ccttgtagtt
     1021 tttctcaaac gttgctttat catgtgtgtg ttgtaactca atctgcacag gactgttggc
     1081 attagcatac gaaccagcac cgtactgtac ataaccaggt tgaccgactt gataaacaat
     1141 tccgccgtct cccacaatat aagcagtata agcgctagtc catgaacgtt gcatatactg
     1201 cgcttcattg cgtcctgttg ctgtttcatt agccgtttca tgcagtaaaa tatactgatt
     1261 atttgctact tgtgagctac cttcatttgc gcccaaatta aattcattgt tgatagtata
     1321 ggcaaatccg ttaattggca ataaaaaaag agccgttaac aggctcatcg cagtaatagt
     1381 aattttcttt ttcatttgtt tcctccttct tcgctttcag ccgagaacat tttgtaggtt
     1441 cgatttgata cacccaacac actccctaaa aacgcgccaa aaccagtaat gatgacaaca
     1501 cagatatctg tgtactgcca attgagcgct ttaccaacta accccacgaa agtagctagt
     1561 gcgggaataa ttaccagtgc gaaccatttt agtacttcga acgttttatt attcattttc
     1621 ttctctccct aaacaaagtt ttgatttgtt gcgtgtgttc caccaatttt tctgtatgtg
     1681 tatctaatct ttcatcgtgt ttctttagtt cttcatgaat catcaatcga tctgatttgc
     1741 tcgattctaa atctttagtc agcaaatcta aattgtggct tacttttgaa agagtctcag
     1801 taattttcga gaaagatgca gcaatcggtc taattactaa taaaatcaaa gaaacgatag
     1861 cggttattga tcctgctatc attccccatt cccctaaatt aatcatgtga caactccttt
     1921 accttaaata aaaacgcatc aattaagatg cgctcttatc tttattaatg attttatctg
     1981 cttcttcgtc tgtaatgcat aatggaacga aaaccattac ttgttcgtta gtgaaacagc
     2041 cccagtcata cattagtttg atatcttcat atgaatacat gttacttccc accttgtaat
     2101 tgttttttga tttcttcgat ttccttggta ttttgtacag aagcaagcat cgtttttgaa
     2161 ttcaactgcg ctaaactttc tgacttttct ttcaataaga cattttcttg cttgattgct
     2221 acattgttta gcattgcttt agaatttagc tgtttcaatt catcattttc tgccttcagc
     2281 gtttcgtata atgccttaat attagccaat tcatctacgc tatcaacagc attccctttt
     2341 ttctcttctt cagtagctaa ctcaacccac tgttttttat caaaatcaaa tcttggtctc
     2401 cagttaggaa ctggtggttt aatctctgta cagttttcag ggatattttc ttgattgttc
     2461 aaaatgattt gctcgaatcc gtaaggcttg attgatttgt aaactacttt cattagattt
     2521 cctcccttaa attgaataag tgataacaaa tgaataagct gatccataac ttgaatttct
     2581 tctccattta atggctccgt ctgcgccaat agatagttga gcactgttca aagtagaacg
     2641 gtctattgac ccaaccagtt gttcaaaact aattggtgtc cgatagcctt ctggaacagt
     2701 taaaataacc gaatcattcc cgccactact ttttccgttt aaagccacaa aatatataga
     2761 aactgttttt ccttcacgat aaagctttgc tgtccctgta ttaccgttag tgacaaccag
     2821 atttaccact tcatatctgt tatcatcagt cgtcaaaaca cgtttattat tgattgttac
     2881 agaacctgaa aaattcttat gtcctgcaat ggcttggtct ccatctgtct gcaccaatgc
     2941 ttctttacca tcaatagctt ctacatgcgt ttttaagtat ttagcaactc cgtcttcttt
     3001 taattgaaca atatcagcca ttaaaccgtc cccactttct caaatgtaat attcgctaat
     3061 ccatcaagtt tcactttatc ggttgctgac attaaacctg ctgtcgtagt tgtagcatta
     3121 cctggatttt tctgtgctcc agctgcaatt ccatccaact tagttttatc tgtggacgac
     3181 atcaacccat ttgctgtagt tgtagctaca gctgtagttg tggcatttat tccaggatca
     3241 cctttatctc cctttggtaa aacaaaatta aatctagctg cagatgatgt tcctacattc
     3301 gtaacagaag cggttgaacc actagaaacg gttcctatgg taattgttgc tgcttggcca
     3361 ggatcgcctt tatctccctt caccgttgtt ggtttgcctt ctatagcatt ccaatgagtt
     3421 tgtggataaa cctgtacatt gctttgtttt atttttacga tatctgtcat tctctatacc
     3481 tccccaattt tttcaaaagt aaaatttgga attctttcgt ttgtgtaatt ttctgcttga
     3541 tttacagctt cttggaattt
//
LOCUS       DAFLVO010000155         3559 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.160, whole genome shotgun sequence.
ACCESSION   DAFLVO010000155 DAFLVO010000000
VERSION     DAFLVO010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3559
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.160"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            45..863
                     /locus_tag="L1U99_002919"
     CDS             45..863
                     /locus_tag="L1U99_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBN1213415.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAVNENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWMVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
     gene            867..1163
                     /locus_tag="L1U99_002920"
     CDS             867..1163
                     /locus_tag="L1U99_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213416.1"
                     /translation="MIEVKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETTSSLVAK
                     LKSDSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(1345..1698)
                     /locus_tag="L1U99_002921"
     CDS             complement(1345..1698)
                     /locus_tag="L1U99_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213417.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDRNDSKVAEVKNKPTDHNPIQQEHPSTVTSDHSAKKEK
                     PMLKGFNAPSNKDLL"
     gene            complement(1718..2773)
                     /locus_tag="L1U99_002922"
     CDS             complement(1718..2773)
                     /locus_tag="L1U99_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HBN1213418.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNVSEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYQNI
                     LSFSLANLARLEDQSDDVLTANLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDETLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            2989..3387
                     /locus_tag="L1U99_002923"
     CDS             2989..3387
                     /locus_tag="L1U99_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213419.1"
                     /translation="MRLRRNKNYTTIILEDFTDQELLIVGKTKADFIEKGNASIVKAS
                     KIAVEKYFDSLEESAKEIFNGEKAGSYELDGIRFSLIPTTENIIPKKLYYIFSSEKHT
                     SMKPCIFDWQWLIDAVLDVKCSKYNITLGC"
     gene            3390..>3559
                     /locus_tag="L1U99_002924"
     CDS             3390..>3559
                     /locus_tag="L1U99_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213420.1"
                     /translation="MSMLVRKLPLSVREFLFYLVCLIASGFKLIEHIFIFAYVLAMIA
                     FLSGGWLIIYLL"
BASE COUNT         1167 a          524 c          662 g         1206 t
ORIGIN      
        1 agtgtataat ggagttacaa aaggttaata agggaggttt aatcatggaa aagaagttgt
       61 caatcattac tggaaacatt gaaaaaggtg gaacaggtaa aacaacaaca atctacaatc
      121 taggtggata tgctgtcgaa aatttaggta tgaaggtgct gtatattgat gaagataagt
      181 cgcaaaacct atcaaaacga tttcctgatg ctttcagtaa agcgaaaaga gagaatacaa
      241 tcaatcattt atatcttcat ggatcagctg aacctttagc tgtaaatgag aacatggata
      301 ttttagtagc aggtgaagat ttaaaacaag ttgagatgca aatgcgtgat atgcctaaca
      361 acagaaccct actgtttaga tggatggttg ttaactatga acagcttaaa gagaagtatg
      421 atctaattct gattgatact cataatgatg caggtctact agctcaaaat gcttgggctg
      481 tatctgatct tgtcgtaggc atttctgatc catctaaaga tggttttgaa gctttgctga
      541 agcttggtaa agatattgat gcactagcaa aacagttgat tgatattaag actggtgaaa
      601 cactgatgga aactaaatac gctacgatcg gtagcaggat caaacataat actaattcaa
      661 gtcgtgagtt cctagaactg gtaccaacgt tatctaatta tcttggatat gtacaagaga
      721 aggaattgct taatgcaact agcttagaag gtaagaatat tgctgagttc gctaaggata
      781 agaatatcta tcgtaagaat aaggatttct ttgaaagcac gtttacgcta tacaacaaaa
      841 taattgatac ggcacaagaa taaggagtga ttgaagtgaa agaaaataga tttaaaaaat
      901 tcgctgaagc tgaagtagaa gaagttcctg aagtggttga agcagttgaa gaacctaaac
      961 aaacacctaa agaaacaaca agttctttgg tagctaaact aaaaagtgat agttctgaaa
     1021 agaagaaaaa ttatcaattc acgcttcaac catcgcaaag aaagaaacta tctaaaatca
     1081 gcgaaaagtt aggaattcga tcagattcag ctttacttgg tgaaatgata gataacttgt
     1141 atgatgaagt ttttggtgag tgatcagttt aaagctgatc acttttttta ttggaataag
     1201 cggttaggta tagcttaact aaatttaata tacgtgttta tggatatata cgtatacatg
     1261 tttatataca tgtatacgta tatgtttatg tttatatttg tacataataa aaaggctagg
     1321 tattgtaacc tcgccttttt atttttaaag taagtctttg ttacttggtg cattgaaccc
     1381 tttcagcatt ggcttttctt tctttgctga atgatcggat gtaaccgttg aaggatgctc
     1441 ttgttgaata gggttatgat cagttggttt attctttact tctgctactt tgctatcgtt
     1501 tctatcgttg cctgcttcaa taattgtaac ttcattgttc tttacacgcc gatataggtt
     1561 caaagctttt ttgatcgtct gagagtattt aacgcctagt gtttcatatt cggattcaag
     1621 aaactctgct aaaggtaact cgctaacctt ttctctattg attataacta cataacgctc
     1681 tgattttccc ttattcatgt tgatctcctt cgctgtttta ttgagttaaa ccaaacttgt
     1741 aaaagccttt tacattagaa aattcactgt cttcaacaaa caaggtatgc ggaattttat
     1801 cttttacaag ttgtttgtcg ataatagaag ctccaccacc agtaaagaca actttatcta
     1861 aggttgtgaa gtttttgaat gtagctaaaa cttctgcaac aaccatattg gtgtatgttt
     1921 ttatttctct ttcaactact tctgaaatat caaaactttc atttccgctt ggcttaaata
     1981 gatatacgcc tttttctttg ccttctcgga taatcttttc aagttggaaa gcattaggac
     2041 tgatcggaag gtcaagcata tttacgatac gattatataa agtaaaaatg ccggtatcct
     2101 tttgttcacg attgttttcg tcaatttcaa aattttggac aacatcaaaa agtttcgtgc
     2161 caccgccaat atcaacaaaa ccgatcttct gactgatcaa tgtttcatct tgtacactac
     2221 catcatcagc aagtaggagg ttatatagtg ttccaatcgg ctgtggcagt acccaaacgg
     2281 tatctacgtt tatattataa gctttaccgt caacttcaac tgaatgttgt cgtgtggctt
     2341 gttgcatcac gtatttgacg attgtttcgg tatagtcgga tgaaggcaga cctaaaacta
     2401 gattagcggt taaaacgtca tcagattgat cttctaaacg tgctaggtta gctaaagaga
     2461 aagataggat attttggtag gtttcctgct tgtatctgct gatcccaaaa cctagtgatt
     2521 ctatcacgta gtcatctttt cctagctcgt gtatatcctt cccaaagtaa tagctttcag
     2581 tagtgtttac taggctatat tcagaaacgt ttagtgatcg ttttaatgag gaacctatat
     2641 tagaaaaacg tcctgaatta atgatatttt tgttcaaaat acgagaggga agtgagagtg
     2701 gagaaacgtg tgtactcatt tcttttactg atttattccc taagtcaacg gaaaacaata
     2761 atggttcttt catggtatga cctctttctg tttgtgttta tggtatttcg gtacgaaaat
     2821 agtttacacc tatttactat tagttgcaac tgtttataag aaaaaaatgc aatcataaaa
     2881 gtctaattaa ttataataaa gtgtaaataa aaaggtgtaa ataaatgctt gcaaatttat
     2941 cttattatga tattataaaa acataaatta tattaaggag tgatcctgat gcgattgaga
     3001 agaaataaga attacactac cattatttta gaagatttta ctgatcaaga attacttatt
     3061 gtcggtaaaa caaaagcaga ttttatcgaa aagggaaatg cttcaatagt aaaagcttca
     3121 aagattgctg tcgaaaaata ttttgattct ttagaagaaa gtgctaagga aatttttaat
     3181 ggagagaaag ctggtagcta tgagttagac ggtattagat ttagcttgat cccaacaact
     3241 gaaaatatta ttccgaagaa attatattat atcttttcat ctgaaaaaca tacttcaatg
     3301 aagccttgta tttttgattg gcaatggttg attgatgctg tattggatgt aaaatgttca
     3361 aaatacaata ttactttggg gtgttaatta tgagtatgct agttagaaaa ttaccattat
     3421 ctgtaagaga atttctattt tacttggtct gcttaatcgc atcagggttt aagctgatcg
     3481 aacatatttt tatctttgct tatgtattag caatgatcgc atttttatct ggcggttggt
     3541 taattattta tttgttaag
//
LOCUS       DAFLVO010000156         3551 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.161, whole genome shotgun sequence.
ACCESSION   DAFLVO010000156 DAFLVO010000000
VERSION     DAFLVO010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3551
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.161"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..985
                     /locus_tag="L1U99_002925"
     CDS             <1..985
                     /locus_tag="L1U99_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBN1213421.1"
                     /translation="NHFKYLILSFISTFLNIAISVALMQTLYFDDKYVGRVVGGTLSF
                     VLIGLVIYLRIMIKGAHFFDKKQWRYALKISLPLIPHSLANIVLAQFDRIMINSYLGP
                     AAGGIYSYISNIGIILSVIWMSTNNAWVPWFYGEMSKNNEKKVKKVSNYYLVVFTLIT
                     MIVMVVSIDLAKFMAPKDYYSGLSLVVPITLGYFFQFLYSLPVNAEFYEKKTSFIAIG
                     TVASAIVNILLNMIFIPRLGIIAAGYTTVFTYFLLFIFHYNIAKKITNKQLFDTKKIC
                     IIIIFVSIFSLILHILINQMLIRYVLTSLLIISLVIYFLKIKNRIIDDYNS"
     gene            998..2005
                     /locus_tag="L1U99_002926"
     CDS             998..2005
                     /locus_tag="L1U99_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBN1213422.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            2017..3021
                     /gene="neuB"
                     /locus_tag="L1U99_002927"
     CDS             2017..3021
                     /gene="neuB"
                     /locus_tag="L1U99_002927"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HBN1213423.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            3018..>3551
                     /locus_tag="L1U99_002928"
     CDS             3018..>3551
                     /locus_tag="L1U99_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HBN1213424.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDT"
BASE COUNT         1258 a          450 c          672 g         1171 t
ORIGIN      
        1 taaccatttt aaatatttga ttttatcttt tatatctact tttttgaata ttgcaatctc
       61 tgtagctttg atgcagacat tatattttga tgataaatat gttggcagag tagtcggcgg
      121 aacactgtca tttgtgttga taggtttagt aatttattta agaataatga taaagggtgc
      181 tcattttttt gataaaaaac agtggagata cgctttaaaa atctctttgc cgctaatccc
      241 acattcctta gcaaatatag ttttagcaca attcgataga attatgatta attcttattt
      301 aggtcctgct gcggggggaa tatattccta cattagtaac ataggtatta ttctaagcgt
      361 aatatggatg tctactaata acgcctgggt tccatggttc tatggtgaga tgagtaaaaa
      421 taatgaaaaa aaagtgaaga aagttagtaa ctattattta gtagtcttta ctttgattac
      481 gatgattgta atggtagttt cgattgattt agcaaaattt atggctccga aagactatta
      541 ttctgggtta tctttagtgg ttccgataac cttaggctat ttctttcagt ttttatatag
      601 tttaccagtt aatgctgaat tttatgagaa aaaaacatcg tttattgcga ttggtacagt
      661 agcaagtgct atagttaata tactattaaa catgattttc atacctaggt taggaataat
      721 tgctgctgga tacacaaccg tatttacgta ttttttactt tttatttttc attataatat
      781 cgctaaaaaa attacgaata aacaattatt tgacacaaaa aaaatatgta tcataataat
      841 ttttgtatca attttttctt tgatacttca tattttaatc aatcaaatgt tgattcgtta
      901 cgttttgaca tcattattga taattagttt agttatatat tttttaaaga ttaagaatcg
      961 aattatagat gactataatt cataggagga gatataagtg tttaaaggaa aaacaatatt
     1021 agtaactggc ggaactggtt ccattggaag tgaaattgtt cgtcagcttt taaaatatga
     1081 accaaaagct atcagaattt atagtagagg tgaagaaaaa caattttata tgcaacaaga
     1141 gctctcaaat cacactaatt tgagattttt aattggtgat atcagagact ctcaaaggat
     1201 tgattatgca tgtcgtgatg tggatattat ttttcatgct gccgcaatga aacacgttcc
     1261 agcaagtgaa tataatccta tggaagctgt aaaaacaaat gtgatgggaa ctcaaaatgt
     1321 aatagatgca gcgatcaaaa ataatgtaaa acattttgta ggtatcagta cagataaagt
     1381 agtgagtcct actaacacca tgggtgcgac aaagttattg agtgaaaaat taataatagc
     1441 tgccaatcag tataaaggaa aaacagaaac aatattttct tgtgtaaggt ttggaaatgt
     1501 catggggtca agtggatctg ttattcctct ttttagtaaa caaataaaaa acaataaaga
     1561 tattactttg acagatgttg atatgacacg atttatgatg tcaataccgg atgctgcaag
     1621 attagttctg tctgctgcta tgaattcaaa atttggagaa acatatgtct taaaaatgcc
     1681 ggcaatcaat attttaactt tagctcaatc attaataaaa atatataatg atacacatga
     1741 tgaaaaatat agaggtgaaa taaaagttgt aggtatcagg ccaggagaaa aattatatga
     1801 agagctaatg actacagacg aaattgaacg ctcatatgaa aatgataaaa tgtatatcat
     1861 tccaccacac tatcatgcta ctgacgaact gtacaaagat tatgaaaaaa ttaaaatcac
     1921 tgcatactct tcagatgcaa cagaattaat gagtggacag gaatttatta gaatcgcaaa
     1981 agagaataat gtcgtgactt ggtaaggagt tttatgatga aatcagaagt atatgtaatt
     2041 gcagaaattg gtgtaaacca taatggaagt ctagatttag ctttagaaag tattgataaa
     2101 gctaaagaat gtggagctaa cgcggttaaa tttcaaacat ttaaaacgaa taagctagtt
     2161 tccaaaaagg ctccaatggc aaaatatcag aaggataatc ttaaagagga cagttctcaa
     2221 tttgaaatgc taaaaaaatt agaattatct caatctgatt ttattagaat aaaagattat
     2281 tgtatacaaa ataaaattga ttttttgtct actccttttg atgaagaaag tgcagacttt
     2341 ctaaaacaaa ttggtgtaca aggatttaaa attggctcag gagatttaac aaatttacct
     2401 tttcttagaa aaatagatat gtatgggttg ccagttttat tatctacagg tatggctgat
     2461 attcatgagg tcagtgaggc tgtagattgt ttcatagata gtccagttac tattttacat
     2521 tgtacttcaa attatccggc tagttctgaa gatattaatt tattggcgat taacacatta
     2581 aaagaaatgt tcgggatacc cgttgggtac tccgatcatt cattgggata tgatgttggt
     2641 atttgtgctg ttgcgatggg tgctaaggta attgagaaac attttacctt ggataaggaa
     2701 ctacctggtc cagatcataa agcttcttta gatcctcagg aatttgcaga ttttgtaaag
     2761 catattagaa acactgaaat atttttaggt gatggtgtta agcgagcaat gccttctgaa
     2821 cttagtacaa aagaagtatc aagaaaaagc ctagtggtca ctgagaattt aaatgtggga
     2881 gatattctta cagagaaatc tcttacaata aaacgtcctg gaaatggaat agctcctaag
     2941 tttttatatc aatatattgg caaaaaagtt aaaagaccaa taagtgcaga tagtgttctg
     3001 cttgaggaag atgttgaatg aaaaaaatac ttatagtaag tggaacacga gctgattatg
     3061 gaatatataa acctgttgct gagaatttac tacaagataa ttgggatgta tcatttgttg
     3121 tttctggaat gcatttatcc cataaatatg gatttactaa agaattgatc ttagctgacg
     3181 gatttagaat tagtggagaa gttcaaagtt tgtttttaga gaacaataag ggaaacatgg
     3241 ctcggtctgt ggcattagag ataaatggtt tcacaaatat atttgaacaa actagccctg
     3301 attttgtatt attactaggg gatagaggag aaatgttggc agctgcgata gcttgtttgt
     3361 atcttggaat caaaacagca catattcacg gaggcgaagt gtctggtact gtagatgaat
     3421 caataagaca tgccataacg aaaatagcat ctgttcattt tgctgctacg gaaaaaagca
     3481 aagagcgttt aataaaaatg ggggaagatt cttggagagt ttttcccgtc ggagctccta
     3541 gaatagatac t
//
LOCUS       DAFLVO010000157         3534 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.162, whole genome shotgun sequence.
ACCESSION   DAFLVO010000157 DAFLVO010000000
VERSION     DAFLVO010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.162"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..2303)
                     /locus_tag="L1U99_002929"
     CDS             complement(<1..2303)
                     /locus_tag="L1U99_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213425.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAPGAYQLVET"
     gene            complement(2975..3243)
                     /locus_tag="L1U99_002930"
                     /pseudo
     CDS             complement(2975..3243)
                     /locus_tag="L1U99_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT          985 a          785 c          561 g         1203 t
ORIGIN      
        1 gtttctacca gctgatatgc tcctggtgct aaaccgtcaa ttgccagttt tccatcttct
       61 cctgtagtta aaccggtttg tagcgtttct ccttctcggt tctgtaactc aaaaacagct
      121 ccttgaagga cttcaccact gccttcagca tgtttaatta gttcaacacc acccgtatca
      181 aggatgtttt caatggttaa cgtcacttct tctatggagt attcatttat aaaaacatca
      241 tgtaccgtcg catctaaaag atacccttcc ggtgcttctg tttctcggac ttgatagcta
      301 cctacaggaa gcggttcact taaaaattct ccgttttctg ccgttatacc ttcttgtatc
      361 acttgtgaat cgcttgataa aatttcaaat tttgctcctg ccagcctttg gccattctca
      421 tcagttttaa ttactttaat acgcccatcg attttccttg ttcttacagt actcgtattc
      481 aatcgattgt cactattcac aagcgttgca aagtttaaaa tttgatcgcc gaccgcatac
      541 gcctctacat tgaccttaaa agagagggta aaacttgtcg gaccaccaat cgtattattc
      601 gcactgaaac gaactattcc attattgact tcggcatcaa tgaaagaggg aatatctgat
      661 agaaatgaca caaattccat gccttcttcc aaaacatctt caataacaag cgtatttctt
      721 gttccagaaa acatcgagac atgcagagta tacgttagtt cattttcatt gagattgata
      781 acatttttgt ccacactttt tcttaaagag attgccggaa gattactttc agggattctc
      841 aagcggtagt ctcggctcat tacctgatta ttgtaggtca tactcgctcg attccgagaa
      901 aacccatcct cttgtcttcc ttcattgaac aagtcgacat cggtcacttc aagagcatat
      961 tcaataaaat acgattgacc ctctgctaga ttaccaaagt ccacaacaag tgtattcgtt
     1021 tccttattaa aagatacttt gtccacaaat tcctcggaaa cataatgagt tctaacgttt
     1081 gcttcacctg gattcgttac ttctgcgatc cgaaccccac ctgaaatagg ttctctattt
     1141 ccagtggaac tccatgtagt cggattcggt gccaaagttg ttccttgcgg tagtacatcg
     1201 gtaaccacta caccgtcttt tcgtgatcct tcataattta cctgcaaaat aaatttatta
     1261 ctgttggtca cgtcttgccc gtcaatcagc agattcccaa gatttccttg gctgtcgatt
     1321 tctctagagc catagtataa tttcgaaaaa atgggtcttg atgaaggaat aggcgtaatt
     1381 gaaaattccg tgtttgctgc tcgctcagca taagtaagac tcacttgaaa gtcattattt
     1441 ggctcagtac cgcctgattg aaagaaagca acttcaaacg tgatactgaa tgtatacgac
     1501 tgagcggctt catttaatcc ttcataatca aaggtaaatg gaaaaacaac gtctgtgcct
     1561 tcttggtaaa atgccagtgg ctttaaaggt gaatcatcag cgacctccac tctaatgaac
     1621 tcaattaagc caatcgatgc tctaggaact cgtacgacca tctccccata ttcttcaaga
     1681 atatcgccag cgcctccttg aatgtatccc tttaacgttt gtgtatgcct gctcggcaaa
     1741 gtggggcgct cagcagagat gccgatgtca taattcaaga gctcctcttg tctttcaatc
     1801 tgagattcct gcgttataga tggctcagat gatctggctt cattaaaaga ttcacttaag
     1861 ctttcttctg gtatattaaa agattcactt gtgctttctt ctggtacatt aaaagactca
     1921 cttgtgcttt cttctggtac actgatttct attgagaccg tatttgattg aatatcaccg
     1981 cttcttgcgg tcaattcgta tttacctgaa tgctgggaag aataagtaat cagacgttcg
     2041 taatcattga gttgcttcac ttccccttca atcaaatcct cactcttatc aatgaccaat
     2101 gcatttagca ggtctggtgt tcctctgact cgcaactgga actgctcacc caaagcagcc
     2161 tcctcttgat caacttcgat cgtcagcgaa cgctctggct gttctgctaa agactcagct
     2221 agaaccgtta tgttcccaaa ttgattgatc acaataagca taactagaaa catacttaac
     2281 agtttatgaa atttgttcct cactattact cccccttata attttgacta aacaacaagg
     2341 tacccgataa ttttctaaaa agattcccca actcaaaatg gctgcgttac ctccctcgta
     2401 ttttcggttc aactcaagcg ttgcaatgta agctgtaaac aaagctaatg attgccgatt
     2461 gtcttctgtt gattgattcg atagctttgt atgactttta gttgtccgtg tggcttaacc
     2521 ataattatga tttcacgatt cctcctgcca gtgccttgca caagctggag cgtaacccta
     2581 atagttattt tgttaatgta cttatatact tttatacttt tccattagaa acaatcacta
     2641 aatcgttgat accaaggtca gactctagaa tttcatcagt gagtccctgt attggttaac
     2701 cttcatcaat cccaaaaaaa tatatcaatg cttagcatca aaatgaatat atagtttaga
     2761 atacttggga ttcatcgata actgatcgct tatttggcca tattatttgg cacttggttc
     2821 aactaaacgc atttaggatg ttccttcatt ctcgtcatgg atgttctcaa accgtcatta
     2881 ctaataaact gtccaccgaa tcgatggttc atttcttgca ttttccacgt ccaattactc
     2941 tttttgctct ttatttgggc gtagtttcac tttcttaact tgtatcgtct tccatcaact
     3001 ccttaatcat cttcttagct ttattggctc ggtttccttg taaaaggtat ctacaaatag
     3061 tgacaatctg tattaaatct tcatcatttt ctgtaatgtc aataatttct atattctgta
     3121 ccatatattg caaagggttt cactaagttc ataaccgaag cgaattaaac aacttttgta
     3181 tagaataact accttttcta tttttccatt ggtaattcta tctattaatt ggtttaatcc
     3241 ttttgttgta gttgattcca ctaccaagat gattctctcg aattttaaag cttgaagatg
     3301 tattgctatt tttgctaact ggcgtatttg caactatttt tcccttctat tcttccttca
     3361 ttgattcccc tctaaaatta ctatccataa aaaattgcat aaatgacaat agtatttata
     3421 ttagtcatac tgctttttaa cacagcaaat tccagaaaaa cattcgttac atatttgtga
     3481 atttttccaa aaaataacat ttttataaaa cgacgaaaaa taaatcacta ccag
//
LOCUS       DAFLVO010000158         3397 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.163, whole genome shotgun sequence.
ACCESSION   DAFLVO010000158 DAFLVO010000000
VERSION     DAFLVO010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3397
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.163"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(144..761)
                     /locus_tag="L1U99_002931"
     CDS             complement(144..761)
                     /locus_tag="L1U99_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213426.1"
                     /translation="MGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTVTAAT
                     EANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVKVGDR
                     WENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNGLVSIKGT
                     GKRTIVEVSSTYPTTMILSLLISSITFIFLFTRYLIRCCGEMKID"
     gene            complement(823..1503)
                     /locus_tag="L1U99_002932"
                     /pseudo
     CDS             complement(823..1503)
                     /locus_tag="L1U99_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            complement(1825..2046)
                     /locus_tag="L1U99_002933"
     CDS             complement(1825..2046)
                     /locus_tag="L1U99_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213427.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(2144..2389)
                     /locus_tag="L1U99_002934"
     CDS             complement(2144..2389)
                     /locus_tag="L1U99_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213428.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            2629..3243
                     /locus_tag="L1U99_002935"
                     /pseudo
     CDS             2629..3243
                     /locus_tag="L1U99_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
BASE COUNT         1067 a          627 c          505 g         1198 t
ORIGIN      
        1 tctatatttt cattaaattt tatatttgct cttttcactt ttcggaataa attcactgtg
       61 actcttgata ccttctttta tatattgcta atgtattttc tccattgcta tgaaaataga
      121 atcaacatat ttataatatc tatctaatct attttcattt caccgcagca tcttattaaa
      181 taacgtgtaa ataagaatat aaaagttatt gaactaatta ataaagatag aatcatcgta
      241 gttggatacg tagatgaaac ctcaactata gttcttttcc ccgtaccttt aatagacact
      301 aaaccattgt cattttctat agtgctcttt ttcccattta ctttcacaac tgttccccaa
      361 taattgaata caggtaatgt gatattttgc tcatcggcat cttctactgt atagactatt
      421 ttggaattat atgctttatg agatgcattc tcccaccgat caccaacttt tacttcatgt
      481 ttctttaaat gatctttata tttcaatgca tctaatggtg catagtcata taggcctcca
      541 gttcttgagg atgtataacg tgtaacatct tttttggtca taactaaacg acctttatac
      601 gactgaattt tatgcgaata atttgcttct gttgctgcag tcacagtaaa aataataaga
      661 actattccta caaggctcca catacttttt ttgttgcttg ttttccactt taaaaacact
      721 atggttaaga ttaatgaacc aaaaagcact tgaaaaccca aggttctcgg ttctgttgcg
      781 aagtttgaaa atcaaacgcg ccctctctga actccaaata tcttaggctg ttattcccat
      841 taataccttg atttcagtag acaccgaaaa gccgaagagc gttccatttc ttcggttctt
      901 tttatatatt cctcgaatgg tctccatgcc cttaatcgtg gaagaggctg tacggagact
      961 ttgataaaat ttatttcgtc gtttaatagg tcgatggtct tgttctatta aattgttaag
     1021 atacttcaca gttcggtgct ctgtcttagt atataaaccc acactctgta actttctaaa
     1081 ggcggagcca agagaaggtg ctttatcggt cacaattgct ttcggctcac caaactgttt
     1141 atggagtcgt tttaagaaag cataggctgc ttgcgtatcc cgtttctttc gtaaccagat
     1201 atctaaggtt aagccgtccg catcaattgc acgataaaga taatgccaac gtcccttaat
     1261 tttgatatag gtttcgtcca ttttccatga atagaaggat tgtctatttt tcttcttcca
     1321 aagataatag aggactttgc tgtactctta tacccaacga taaatcgtag tatgacaaac
     1381 atttattcca cgatcatata acaattcctg aacttcacga tagcttagat tgtaacgcag
     1441 gtagtaacca acagcgacaa taatgacgtc ttttttgaat tgtttgcctt taaaatgatt
     1501 cattactctg tcctctctgt cttttttctc aattttacac taaaatagat tttttggaaa
     1561 actttgcaac agaaccgttt ttactatata cttcttccca gaacttgtcc gtctccttca
     1621 aattatctct acctctcgag ttcattgggt ggtttgccca tttattaaac atggaatcac
     1681 ctttctcata ctcatatatt tatgtcctat ttcaattata tttatatatg cttaaataaa
     1741 tttgtatcct gaaatttatt gtaatatgaa gctgtatttt acatatagta accaaagagt
     1801 taataaaata aaaagagcga accattatag atcagctctt ttttcattgc tgtttttaat
     1861 cttatctaga atcacttcaa atgtttcaaa ggtatttaca tctaactgac ataaccaaag
     1921 caagtacttc ttttctttgt aagtccaatc aatattacgg taagaggaca ttagattatg
     1981 gtaccttgct ctttgttcaa ctgaagccaa ttcccagcgt ttttcaaata ttttttcttc
     2041 ttccattatt gatccctcgc aagacgctac ctcaaactta aataatgggc agcgaaagtc
     2101 taattcctta gatctaagta tagcaaacaa atatgaaaaa aacttagaag gtagtaaaag
     2161 ttcttccgtc ttttgctttg cttctattct taatgtgttt cgttatcggt gccctacaaa
     2221 gattttcatt aattacacac tcatttattg ttgtgtattt tctgacattt ctctcttgat
     2281 caattatttt aattccatgg gcatcctgat agttcatagg agaggagcgg ctatcagaaa
     2341 tagttgcacc tatctcttga acttctttta caacttctgg aaaatccatc catcctgctt
     2401 cagctgtcaa aagtaataat ctataatatt tatctttcct tttcaatcta agaaatcgtc
     2461 accccattct ttttcttcta ttataaacta tttaactttt agaattcaaa aaccgtttgt
     2521 ctatttagag tttaccctaa atagacaaaa atataacatt gaaaaattta gagttctaac
     2581 gtatgattag ggtgtattat aaacgttata gaaaagtagg gaataaattt gaaaattgct
     2641 tatattagag tttcatccat cgatcaaaat gaacaacgtc aaattgaaga aatgaaaaag
     2701 tttggcgctg aaaaaatttt tatcgaaaaa caatctggag cgacgattag tcatcggccg
     2761 attttccagg aagctttaga ttttgtcaga gagcaagata tttttattgt agaagccatt
     2821 gatcgacttg gacgcaatta tgacgagatt atcgattcag tgaattatct aaagaagaag
     2881 aatgtgcgac ttattatcac cagtttaccg atcatggctg aagcaattgg aaatcctctc
     2941 ctagataaat tcatcaaaga cttaatcatt taaatctcag ccatgattgc tgaacaagaa
     3001 cgtactgaat cgaaacgacg ccaggcacaa ggaattaaaa tcgctaaagc aaacggcgtc
     3061 tataaaggtc gtcctaagtt atacagtgca gacaccaaag atcctcaacg tcgccttgtc
     3121 tataggagta tcgttcagga tcttgagaat ggggttgcta tctcaaagat tgcaacagac
     3181 tacaatgtga ctaggcaaac aatttaccga ataaaaaaag aaatcgacca actaattgta
     3241 tgatttcttt tttgaatcac gtaattatta attagctttg tcatcaatac agacaatcat
     3301 tttagattca tctagctaag ttgattacat ttatgttaaa aagaatttag ttaacataaa
     3361 tataattgat gcataaatcg tccttattta aaggcat
//
LOCUS       DAFLVO010000159         3295 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.164, whole genome shotgun sequence.
ACCESSION   DAFLVO010000159 DAFLVO010000000
VERSION     DAFLVO010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3295
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.164"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..562
                     /locus_tag="L1U99_002936"
     CDS             <1..562
                     /locus_tag="L1U99_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HBN1213429.1"
                     /translation="KFEKKKYVLQVFHPVVTELENIEKQILALINSMEQQSQPIICIL
                     PNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTILKECKFMIGNSSSGIIEAASFK
                     IPVINLGTRQNGREQSKNIINANLNENEIETALNKIQDPQFIKSLKNVKNIYGDGNSS
                     RRITKTLNQILNDGEDIKWIQKQIAY"
     gene            535..1212
                     /locus_tag="L1U99_002937"
     CDS             535..1212
                     /locus_tag="L1U99_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBN1213430.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            1202..2344
                     /locus_tag="L1U99_002938"
     CDS             1202..2344
                     /locus_tag="L1U99_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBN1213431.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            2357..>3295
                     /locus_tag="L1U99_002939"
     CDS             2357..>3295
                     /locus_tag="L1U99_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1213432.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDK"
BASE COUNT         1235 a          420 c          626 g         1014 t
ORIGIN      
        1 aaaatttgaa aagaaaaaat acgttttgca agtatttcat ccagttgtaa ccgaactaga
       61 aaatatagaa aaacaaattt tagctttgat caattcaatg gaacaacaat ctcaaccaat
      121 tatttgcatt ttacctaata gtgatgctgg tagcgaaatt atcagaaaaa tgtaccagaa
      181 atatttaaaa acggatatta tttatattac gaatttagag ccggaggaat acctgactat
      241 attaaaagag tgcaaattta tgatcggaaa ttcttcttct gggataattg aagctgcatc
      301 attcaaaata ccagtaataa atttaggaac cagacaaaat ggacgagaac aatctaaaaa
      361 tattataaat gcaaatctaa atgaaaatga aattgaaact gctttgaata aaatacaaga
      421 tcctcagttt ataaaaagct tgaaaaatgt taagaacatc tacggtgacg gcaacagttc
      481 tagaagaata acaaaaacat tgaatcaaat attgaatgat ggggaagata ttaagtggat
      541 tcaaaaacaa atagcttatt aaaatatact agtgatccat acattattat tggggctggc
      601 ggacacgcaa aagtcattat tgaaacctta agattagaaa ataagttaat atatggattt
      661 tttgatgata agcaaaataa aatgcaagat ctgaaatatc ttgggaaaat aaacgaattg
      721 aatagctggg cggatagcaa aaaaaaaatc tataaattta ttgtagctat tggtgactgt
      781 gtagtaagaa aaaagattat aaaaaaattg aatatgccaa gtgagcaata tggaatagct
      841 gttcatccaa gtgctatagt ggcaaaagaa atttcaattg gttatggaac tgttattttt
      901 gcgaatgctg taattaaccc agatgctgta attggagagc atgctataat aaacacaggt
      961 agcattgttg agcatgattg tagaattaat aactatgttc atttatctcc aggtgtatgc
     1021 ttagcgggtg gagtacatgt aggtgtagga actcaaatag gaattggttc tcaatgtatc
     1081 cagatgaaga aaattggatc ttggtgtatg ataggcgcag ggagcactat tgttaaggat
     1141 attccctcac attccttagc ttatggcaat ccagctaaaa ttaagaaaga aggaattaat
     1201 tttgaattct agaattttat tatcaagtcc tcatatggga ggaacagaag aaaaatatgt
     1261 tgctaaggct tttaaagata attggatagc gccattaggt gaaaatgtgg ataaatttga
     1321 agaaagtatt acaaaatata ctggttctaa gggcggagct tctgcgttaa gttcaggtac
     1381 agctgccata catcttgcct taagactgct taatgttgga aaaaacgata ttgtctttgc
     1441 tccttcattt acttttatag ctacagtaaa tcctatttta tatcaagggg ctgtaccagt
     1501 gttcattgac tcagaaccta atacatggaa tatgagccct gttgcactag agagcgcatt
     1561 agaagaagct gaaagaaaca accaattacc taaggcaatc atcgtagtga atttatatgg
     1621 tcaaatggct gattatgaac gaattttagc tattgcaaac caatttaatg ttccagtgat
     1681 agaagatgca gcggaatcgt taggttctac ttataaggga atttcgtcag gcttatttgg
     1741 gacaattggg atctattcat ttaacggtaa taagatcatc acaacctcag gtggaggagc
     1801 tctagtgtct agtgataaaa aatatgttga gcattcaaga tttttagcaa cacaagcaag
     1861 agatcaagca ccgtattatc aacatagcga aataggttat aattaccgtc taagcaatat
     1921 ttctgccggt atcggacgtg gacaaatgga agtattgaat gatagagtag ctaaacgaag
     1981 agaaattttc aatcgatata aggaagcttt ttctggaatt gatagaattg aaatgatgcc
     2041 agaagtggat ggcatggtgc caaatcgttg gttgtctact ttaacgatca atgattataa
     2101 ttctattgat caagtagtta acgtaataaa taaactaaat gaaaaaaaca ttgaaacaag
     2161 agctttgtgg aaaccactac atttgcaacc agtatttcaa ggggtaaaaa tgtattacca
     2221 tgataataat cttagtgtgt cagaaaagtt atttaatagc ggcttatgct taccttctgg
     2281 aagtaatatg acagatagtg aacaagaatt tgttattgat gagtttaaaa aaatattcaa
     2341 gtaggtgtga tattttatga acataggaat tattggttta ggttccatgg ggaaaagaag
     2401 acttagactc attcaagaac actttaatga tattttacta tgtggtgttg atactaatga
     2461 ggcgagacga aaggaagttg aaaaggaatt tggaatacca acttataata gtctaacaga
     2521 ggcaaaaaat ttgtttgaaa taaattcagt ttttgtttgt acatccccta taacccatga
     2581 atttattata aaagaggctt taaatttaga ttgtaatatc tttacggaaa tcaatttatt
     2641 aaatgaatat tatgatgaaa taatcgaagt agctaaaaag aaagatagat tactttatct
     2701 atcttctaca tttttgaaga gaaaagaaat tcaatatatt aagtctaaag tgacgcataa
     2761 taaaaaaatt tcttatcaat accatgtagg acagtattta cccgactggc atccttggga
     2821 agattatcgc aatttttttg tttcaaacaa aaaaactaat gggtgtagag aaatattcgc
     2881 tattgaatta ccttggatta tagatacatt tgggaaagtt aaatcgttta ctgtaatgac
     2941 ccagaaatta tccaatcttg atattgatta ttcggacagt ttcactctta ttattgagca
     3001 tgaaactggt atagttggaa ctttaagtgt agatgttgtt tcaagagtag ctaaaagaaa
     3061 tttaactata attggtgaaa agattttaat agaatgggaa ggtaacccgg attctctatt
     3121 ttcatggaat gaagaaactt ctagtatgac agatattcaa ttgtacgatg aggttatgca
     3181 tgataataat tattcacata ctattattga agatgcatat ttagaggaga ttaaagaatt
     3241 tttcacgctt ttggaaaaga aaatggaacc ccaatatact tttgaaaaag ataag
//
LOCUS       DAFLVO010000160         3294 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.165, whole genome shotgun sequence.
ACCESSION   DAFLVO010000160 DAFLVO010000000
VERSION     DAFLVO010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.165"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..730
                     /locus_tag="L1U99_002940"
     CDS             <1..730
                     /locus_tag="L1U99_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBN1213433.1"
                     /translation="ITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSF
                     WNIVTGIVNSAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKE
                     KWNALKDTIKGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQ
                     TMTNLVKTPSVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITT
                     KIKTELTRQMKRDAGAVGGTLYAT"
     gene            720..1460
                     /locus_tag="L1U99_002941"
     CDS             720..1460
                     /locus_tag="L1U99_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1213434.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            1457..>3294
                     /locus_tag="L1U99_002942"
     CDS             1457..>3294
                     /locus_tag="L1U99_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1213435.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCEIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWR"
BASE COUNT         1240 a          400 c          633 g         1021 t
ORIGIN      
        1 cattactact tggaataata ttaaacagtt tttcaaagat acttggaaaa atattaaaga
       61 tacggcatac aatacgtgga tttctataaa aaataccatg attaatacat ggaataacat
      121 taaggactct ttctggaata ttgttactgg aattgttaat tctgctgaaa atgcatggac
      181 aaatctaaaa aatggtgttt caaatgctat taatcgggta aaagaaatct ttaattcgtt
      241 aagggaagtc aatttatttg aaattggcaa gaacatcatt gatggactta taaatggtgt
      301 aaaagaaaag tggaatgctt tgaaagatac tatcaaaggt attgcaggta atatcaaaaa
      361 ttggattaaa ggagctttag atattcattc tccatcaaga tggatgcgtg atatggttgg
      421 taaaaatatt gttcaaggta ttatcgttgg tattgataaa gagcaaagta agttagatca
      481 aaccatgaca aatttagtaa aaacaccgtc tgttcaacct gtagtaaatg gaataagtca
      541 cctaccaatt acacaaacaa agcaaaatat atctgctagt gaaacaaaag aaattcattt
      601 acatttaaat gtttatggag atttacctga ttcaatggtt cgaaagatta ctacaaaaat
      661 taaaacagaa ttgacaagac aaatgaaacg agatgctggt gcagtaggag gaacattata
      721 tgcaacttaa gagaggacaa ttttttatta atcaacatta ttcttctgaa tttaatgtgt
      781 atattcaaaa caggcctgct tctgtttcag ctagtcgagt aattgaattg agagagcgag
      841 aaggaaatga ttctatcatt attgataaag gctattacaa aaatgtgact agaaagattg
      901 agtgttacta taaagcacct tcaattgata tggtgcagga gtgggaagat cgaatcactg
      961 aatggttaga tatgtcgtct tatagtgatt ttattcttta ctatgatgaa caatatattt
     1021 atcaagctgt agtaatagaa ggacctgaat ttaaaggaac aagaaaaaca ggaaatattg
     1081 tcccttttga atttacagtg agtattcgac catttaagga aaattacaat ggtagattta
     1141 ctattcgaca aacagaaact tttgaaattt ataacccaga gaagtattct tcaaaaccgc
     1201 ttattaaatt gagtggttct ggagatgctt ctttttatat taataaggat aaatatgatt
     1261 tgaaatcgtt ggacagagaa ttatttatag attctaaatt agaagaggct tatcgaaaat
     1321 tagatggtaa tttagaacat caggatcagg tcaccttatt tttagatttt ccatttttat
     1381 atcctggaaa aaatgaaatt aaatggacga aaaatattca ttcatttgaa ataatgccta
     1441 ggtggtggag aaaagtatga aaccaagaat atatagtcct actgaaacag atttctcaac
     1501 gaatggctta ggaattttaa aggattgtac aagatgtgaa atatatgaag tagctaatgg
     1561 aaaatatgaa ttagagttgg attatccttt aggaactaga tttgatgaat attttgaaaa
     1621 tgactatcaa ataaaagcaa agccaaacga tcaagaagag tatcatatct tttttattga
     1681 tgataaagat atagatactt ttttaaatac agtaactatt tatgctcaga gtcgtacaaa
     1741 tcgacttgga agacgggtag tcactcttgt ggaagtggac tctaaaactg gtcaagaagc
     1801 gatatcaatt attgaaacta aaatggataa aaaatctgac atacgacttt attctgatat
     1861 tacggctgtt tctagcacaa tctttgaagc gagaaatgtt ttaaattgta ttgctggtga
     1921 acaaggatca ttgcttcaat attggggcgg agaaattaaa cgtgaaccat ttaagctttc
     1981 tttgttaaag cgaagaggtc gcaataatgt tggaacgatt cggtatggaa aagatatgtc
     2041 tggtttgaag gtcaaattag attggacagg tataaaaaca agaattattc catatgctga
     2101 tcctcaaagt gaagtaggta cgactaatcg aatttatggt tcgccagtag atagtgccta
     2161 tattaataac tatcctgatg tctatacaga acatgttcag tttacagaag aacaaggagt
     2221 aaaagacatt aagagcttaa ataaaatagc taaaaattac tttaaaacga tcaatcctgg
     2281 ctgtgataag cctaaagttt ctattacggt tgaatttgat aagttgactg atagtgaaga
     2341 agcgaaagaa tttgcgaaga ttagaaatta tggtctgttt gatacattta aaatatatca
     2401 taaaaaatat aatatttatc ttgaatcaaa ggttagtgga ctacaatacg attctttatc
     2461 tgaaaaaact ttgaaattag aagcaggaga cattcaagtt gctttttatc agcaacaagc
     2521 tgtaactatt caggataaat taaaagatta tgcaacgaat aattatatga gtgattttaa
     2581 tgattatgtt tcttcaatga ttacaggtca aggcagtgca ggaggatatg tagttttatg
     2641 gccaaaagaa aaaccttcca acatctttat tatggataat ccagatttag aaaaggcaag
     2701 agaagtacta agaatgaata aaaatgggat tgctttttct aagaaaggat ggcgggggcc
     2761 ttttaattca gcttggacat tagatagtat atttaatgcc aattttatac aaactggatt
     2821 aatcaaagca gatatctttc aaaattcttt taacaagact ggagatgtat tgaaattagt
     2881 taatggacta ctccaaattt ggaacaacaa aaagaaaata atggagttaa ctaaaaaagg
     2941 aatggaattt tggaattcta agggttcaat tggaacgatt ggaacaactg attctgttgg
     3001 taatcctttt cctggggctt ctactccaac ccctattgaa gataattctt tagttattcg
     3061 tacaaatgga gacggcaaat atattttgat ttctcctaaa gtaggaaaag gattagtttt
     3121 attaggaaat ggtaaagcaa tttattttgg agacttagat gtacaaggaa aacttacagt
     3181 taaaggaaaa gaaataattc ctggacaagg tggtggtcca tcgggaggtg gagaatctac
     3241 tggtgggtat cctagtgaat taaaaacaga tgcagaaaag agagcttgga gaat
//
LOCUS       DAFLVO010000161         3074 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.166, whole genome shotgun sequence.
ACCESSION   DAFLVO010000161 DAFLVO010000000
VERSION     DAFLVO010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3074
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.166"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            83..433
                     /locus_tag="L1U99_002943"
     CDS             83..433
                     /locus_tag="L1U99_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213436.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELTQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            638..1486
                     /locus_tag="L1U99_002944"
     CDS             638..1486
                     /locus_tag="L1U99_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HBN1213437.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDILYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            1533..1727
                     /locus_tag="L1U99_002945"
     CDS             1533..1727
                     /locus_tag="L1U99_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBN1213438.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            1730..2932
                     /locus_tag="L1U99_002946"
     CDS             1730..2932
                     /locus_tag="L1U99_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1213439.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPHYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFLMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDDDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
BASE COUNT         1127 a          544 c          573 g          830 t
ORIGIN      
        1 cgtatataat acaagtcgta gatggccatc tatatttttt aatcaaatcg tataaacttt
       61 cgtataaaaa aggagaattg tgatgccaat aaaaattacc gatctcagtt taccaaaaga
      121 aacactcgaa aaagaatacc aagtcgtcaa tgtcactcgc tggcaaaagg agggcgaaat
      181 tctaggttgg agctacgaat gtatcctacc aaaacttcgc tacgaaaaaa tcagtgtcaa
      241 agtcaaatct gaacatcctg tgatcacgcc ggaagaactt acccaacaag gtttagccat
      301 aattacattt accaatttgg tgattgtacc ttggggacgc tcgaatggac aatttgtcag
      361 ttatgggtta tcggcaaccg ctgatacggc aactttgatt cccagaaaac aaggtaccac
      421 tacacaaaac taactatact atggagtgtt gggtggttag gacgaaacgg cggggcagcg
      481 cccacagagc cgtttctgtc cgttaagacc gcccaacacc ccataggcta gaagggctgc
      541 tacgcaggcc ttccccctta acttgattta tagatcaaca tcaggagaaa atgactggtt
      601 ctttgacaat cgaatacgca acaaggagtg atgatttttg caagcttata atcagaaaat
      661 cattgaaact cccacgtata ttgaaattta tgattatgaa gcaatcatta ctcccaaacg
      721 taaaacgatc gaaaacgaag taaatctgga acgaaaacaa aaattagctt ggatttatga
      781 aaatgatatt actcttgaaa aaagaaaaaa ctatgatgaa ttatccgctc aaggacaata
      841 tgacagttta aaacgcaaac agaaacatta tcaaagtatg cgatttgaga ttgcccgcct
      901 tgtagacacg aattttgaca atcaaacgaa atttttaact ctcactttca aagaaaacat
      961 tcaagacatt gagtatgcaa ataatgaatt taaaaaattt atcaaacgac tgaattatga
     1021 cctctataaa actaaaaaag caaatttaaa gtatctcgcc acgtgggaaa agcagcaacg
     1081 cggtgcaatc cactaccata ttatcttgtt tgatttcccc tttatctcat ttaaccggtt
     1141 aactacgatt tggggtcagg gtttcgttaa gatcaacaag atcgatgtag acagtatcga
     1201 aaatcgcggg cgctatatca gcaaatattt cgataaagag ctggaattga aagagcataa
     1261 gaaaaaagct tttttcaagt cccggaatct caaactacca actgtcacca aaaagatggt
     1321 aaagaaaccc tatgattcca cgaatcaaga tatactatat acaagcgaat atatagttag
     1381 acgtccattt ttttacaatg ctttagcttt aaatgagttg ggaagtcctg aacaagtgat
     1441 ggattttcaa gaaagtaccg ttcattatac aaaaataaag aaataacact attacccaat
     1501 gatagtgttt tctttgaaag tgagtttata caatgaaaaa tacaatttgt cgaaaagatt
     1561 tagaggctct aggatttaaa acacatcaag ctaccacaat aatccgacaa gcaaaaacaa
     1621 gaatggtaaa tcagggatat ccatattata ataataaaag agttggggta gtaccccgac
     1681 aagtaattga agaaattata ggtgttcctc tttcacagga ggaataacta tgaaaacaaa
     1741 atacccttgt gtgtatcaag ataaaaatgg tcgcttttct tatctagttg agttaggaac
     1801 agatcaagtg actggaaaga ggatccagaa gaaaggaaca aaagattctc taggaaaacg
     1861 attctcatca gctcgtgaag cacacaaaga agtcatgcgt ataaaaaatg aatacatggt
     1921 tgtaaatgga tttgcgaatt atgatttaac ttacaaagaa tttatggagc agtcttacgt
     1981 tccacactac aaagctagcg tacaaaaaag tacttggagt tctcgtgagt gtggattgat
     2041 tcagattact gaatttttcg gtgataagaa gcttcgtgaa atcaatgtgc gagattgtga
     2101 aaattatcga atttggttat tgaacgatag cggatactca caagcataca gttcacttat
     2161 gtacggtatg tttcgtaaat cattagacta tgcggtcacc ctgcaatttc tgaatgagaa
     2221 tatttccaaa agaacaaaag caattccaaa aggaaaatca atcgttcctt actggacaaa
     2281 agaagaattt gaagaagttt tggcaaaaat ttataaagat gatttctacg aacatatgtg
     2341 ttttttaatg atctggctat attacatgac tggtgttcgt gtaagcgaag gattagcact
     2401 taattggaat gacgtggact tcaaacgtaa aaagttgagg gttcatcaca ccttggaaat
     2461 gacaaatcaa aaagatttta ttcggaaacc ttacacaaaa actgaaagcg gcttgcggat
     2521 catttctctg gacgatgata caattgaagt gctaaaaaag tggaaagtta ttcaaaaaaa
     2581 tcatggtgta gaacaattta ttcttagcta cactgacctc ccactctatc gttcaactgt
     2641 tcaacgaatt attcagcgtt atgccaaact agctaaggta cccctaatac aaggaaaagg
     2701 attacgtcat tctcatgtta gctacctaat caatgagttt aacgcagaca ttctggtcgt
     2761 gtcgcaacgg ttaggccatt ctagccctga aatcacttta aagcactacg ctcatctatg
     2821 gagccgtaat gatgaaggaa ttgcagaaca aatgacagga aacattaaat ttacctgtgc
     2881 aacaaaatct aaagttgcaa actttaatgg aaatcaagca gtaaaaatct aaccctacca
     2941 tttccctacc aaaatgagga ataggctgaa aaagcactga tataatagct tctttacgag
     3001 gctactcata ttgagtggga ataagacgta aatataatat ggatggggaa tgccgataaa
     3061 tcaacgtttt tcaa
//
LOCUS       DAFLVO010000162         2866 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.167, whole genome shotgun sequence.
ACCESSION   DAFLVO010000162 DAFLVO010000000
VERSION     DAFLVO010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2866
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.167"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..523
                     /locus_tag="L1U99_002947"
     CDS             <1..523
                     /locus_tag="L1U99_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213440.1"
                     /translation="FYYIENGMDIYSGINGILKHYIKALLRYGVLYQEDLSNQIKISN
                     SGKSLLAKYKKLLSPIYKGIDMEAVNSETLFNLVVDEKFANEFFKSKKIERLNNLFPE
                     NAIKAYVDNNKSRLYNWFIPKRLRGKIKIGDQVKVINLNHTKIVTVTELYIAEKEDIT
                     KMKPVIKILDNKE"
     gene            533..1327
                     /locus_tag="L1U99_002948"
     CDS             533..1327
                     /locus_tag="L1U99_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213441.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSRRLRITVEYGTNESATELKQRYLDTRREASKKYDDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNTL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLALAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMNKYRV"
     gene            1356..2474
                     /locus_tag="L1U99_002949"
     CDS             1356..2474
                     /locus_tag="L1U99_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213442.1"
                     /translation="MGNNSIYTPEMQNKIKRLVGLGWMTRGKLDSFSTIKYLLMDIYR
                     QNKQTGIHFLGYDKPEDAPFFVPSSAYRASTSGSMYNLDLFEEGAKMIEYDFNEAYSR
                     IMRNYPLPSNTYLKAKYNTDQAILRAINRPKVRPYENLKTYMFFLVNFEGTAKEGTYA
                     NPKSQSMFADYGENPKTANEPIWLSEIELTLILDYYDIKEMEVLDSHTFLTKKGLLKE
                     YFERIEPLKTDPDTLKLYKNLRTKVFGAIGQKSLREGETSTFDKYSMYNRAYSSMVAG
                     VFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRSEVPEFEELYKLGVVKKKVHTISKEEV
                     EKALEFKNKGFENKGSFGKSKDEVKGVVIDDDFEFDFD"
     gene            2507..2827
                     /locus_tag="L1U99_002950"
     CDS             2507..2827
                     /locus_tag="L1U99_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213443.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFFIEEWEGTENLVLHQY
                     LLKA"
BASE COUNT         1104 a          351 c          609 g          802 t
ORIGIN      
        1 tttctactat attgagaacg gcatggatat ttattctggt atcaacggca tattaaaaca
       61 ttatattaag gcgttacttc gatatggggt tctttatcaa gaagatttaa gtaaccaaat
      121 taagattagt aattctggaa agtcattact ggcaaaatat aaaaaattgc tttctcctat
      181 ctacaaagga atagatatgg aagctgtaaa ttctgaaact ttatttaatt tagttgttga
      241 tgaaaagttt gcgaatgaat tttttaaaag taaaaaaatt gaaagactaa ataacctgtt
      301 tcctgaaaat gcaataaaag cttatgtaga taataataaa tcacgattat acaactggtt
      361 tattcccaaa cggttgcgag gaaaaatcaa aattggcgat caagtgaaag taattaatct
      421 aaatcatact aagatcgtta ccgtaacgga gttgtatata gctgaaaaag aagatattac
      481 aaaaatgaaa ccagttatta aaatactaga taacaaagag tgagtggaat atatggtagc
      541 aaaaaagaat actctaaaag aagcttctga aaaatatcaa gatatgaaaa gacgaggatt
      601 aataccaaag gacaaaaaag gtatatggag agaatttgtt aaggaagtca gtagtgatcg
      661 aagtggcggt gactttgttg gacgatatac agcaaaaggt tatagcaggc gcttaaggat
      721 cactgttgaa tatggaacga atgaatcagc tacagagctg aagcaaaggt acttagatac
      781 acgaagagaa gcttcaaaaa aatatgatga tttcaagagc agaggtctaa ttcctaagaa
      841 gaaaaagggg atttggcgtg agtttttcaa agaagaagat agcaatcgga ataagggaga
      901 cttcattgga cgatacacag caaaaggcta cactaagaat ttagggatca aggttgaata
      961 cggaactggt gaaagttcat gggaattgag aaatcgctat ttaaatacat tgttagagaa
     1021 atataaagca gaattattgg agttgttcga tgttaatgat tttatcgaga tggctgaaaa
     1081 gtatggtcat gaagaaggtt ttatgatcaa tgacattatg gttattgata attttacgga
     1141 tttattagca cttgcgaaaa aagcaaggga tttaagagaa acgcagatgt atctattcag
     1201 aaataaaaac ggaagaaacc ggagaactga atcgagtgag attgaagatt actatgatgc
     1261 ctttacacac gatctgggag cctttgtaga cgagataagt ggtgtaatga acaaatatag
     1321 ggtctagaat aaaaaagccg gagatgagca gataaatggg aaacaatagc atatacacac
     1381 ctgaaatgca gaataaaatt aaaagacttg tcggattagg gtggatgaca agaggaaaat
     1441 tagattcttt tagtacgatc aaatatcttt tgatggacat ttaccgtcag aacaagcaaa
     1501 caggaataca ttttttgggc tatgataagc cggaagatgc acctttcttt gttccaagtt
     1561 cagcctatag agccagtacc tccggtagca tgtataactt ggatttgttt gaggaaggag
     1621 caaagatgat cgaatatgat ttcaacgaag cctattcgag gatcatgaga aattatcctt
     1681 tgccgtcaaa cacttatttg aaagcaaaat ataatacaga tcaagctatt ttgagagcga
     1741 taaatagacc aaaagtaaga ccgtatgaaa atttaaaaac gtatatgttc tttttggtta
     1801 attttgaagg aacagccaaa gaaggaacat atgctaatcc aaaatcacag tcgatgtttg
     1861 cggattatgg cgaaaatccc aaaacagcta atgagcctat ttggttatcg gagattgagc
     1921 taacacttat ccttgattat tatgatatta aagagatgga agtcctagat agccacacat
     1981 ttttgacgaa aaaaggatta ctcaaagaat attttgaaag aatcgagcca ttaaaaactg
     2041 atcctgatac gttgaagctt tataaaaatc ttagaacgaa agtatttggt gctatcggac
     2101 aaaaatcatt aagagaagga gaaacaagca ccttcgataa atacagtatg tataatcgag
     2161 cgtattcctc catggtagca ggcgtattta gagatcgtat ggttagatat gaacagaaat
     2221 acgttcatag cgcatatggg ctattaaaaa ttcgtactga tggattgtat ttcagatccg
     2281 aagtaccaga gtttgaagag ctgtataaac ttggagtagt taagaaaaaa gttcatacaa
     2341 tatccaaaga agaagtcgaa aaagctttag aatttaaaaa caaaggattt gaaaataagg
     2401 gctcctttgg gaaatctaaa gatgaagtta agggtgttgt gatagacgat gatttcgagt
     2461 ttgattttga ctaaatactc tttggaaaag atggtaggag gtaaatatga agaagaaaat
     2521 tgtggaagga aatgtaggtg ttattattct aaaagattca actgactatg ctaaatcaat
     2581 ggcactaaaa gacgaaaaag ttgcacgcat ggataaagat ttagttgaat ttctgatgga
     2641 tgatacagaa agattaaaag gggatcagtt tttgagttta atgaaagaca aaggcttaaa
     2701 cacatatggt ttatttgatt ataagaaatt agctatagag tgggtaaaag aaggagaaat
     2761 attttttatt gaagaatggg aaggtactga gaacttagtt cttcatcagt atcttttgaa
     2821 agcttaatct aagtaaaaca gttctgacta gttatgcttg tcagaa
//
LOCUS       DAFLVO010000163         2861 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.168, whole genome shotgun sequence.
ACCESSION   DAFLVO010000163 DAFLVO010000000
VERSION     DAFLVO010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2861
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.168"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            128..1351
                     /locus_tag="L1U99_002951"
     CDS             128..1351
                     /locus_tag="L1U99_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HBN1213444.1"
                     /translation="MESYQFQVFKLVPSLERRGNRMKITEKNVNPKFETTESNLKKFD
                     LTVTLSNQLVDSIVEMDAMPQKIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSS
                     SSKHSRLKQVIEKLHQQSVIKIQRTKPNGKTEYKVISPLEITEFNDFSDAVSIKFSSS
                     IMPLLTNLEDHFTQYTFDQVVNLTSKYAISFFQLFTKDFNLYEANRDNLTWSTKSLDR
                     LKNPVFSIADLRKKFSIEKKYKAFRDFERRVIKEPIAQLNKYTDFKIDYELIKKGHTY
                     TNIKFLLTRTMSVPVPYKQEQRDPAYLKGAEDKTEKMNQSYLKAMNSKYTKLLIKNFL
                     ISSADLCDLKLMSRLQNKVYPLYDRLSKDRGFESVVNHLSYVATHKEDYTIKNTVKYL
                     EKSITSYLPYVNLYD"
     gene            1386..2153
                     /locus_tag="L1U99_002952"
     CDS             1386..2153
                     /locus_tag="L1U99_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBN1213445.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFKDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LKIDFAKVRKGRNYNFAVQFNISSEFDEKPYREKKLG"
     gene            2343..2741
                     /locus_tag="L1U99_002953"
     CDS             2343..2741
                     /locus_tag="L1U99_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HBN1213446.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
BASE COUNT         1070 a          403 c          487 g          901 t
ORIGIN      
        1 ttctgctgta ttttcaatga aatttgattg gaaaaaataa aatgtgtttt actgacattg
       61 agttatgtta taaatttacg atacatttct tattgtaacg tatcgaaaac aggtctatac
      121 ttattcaatg gaatcgtacc agttccaagt ttttaagctc gtaccaagct tagaaagaag
      181 aggcaatcgt atgaaaataa cagaaaagaa tgtaaacccg aaatttgaaa ctaccgaaag
      241 caatctaaaa aagtttgatt taactgttac tttatcgaat caacttgtag atagcattgt
      301 tgaaatggat gctatgccac aaaaaattta tctttacgct ataggacatc ttgaccctaa
      361 aaatccgcct tttaataata ccgtcaaagt atctaaaaag gctttatttg cgttgatgtc
      421 ttctagttca tcttcttcaa aacattcaag attaaaacaa gttattgaaa aattgcatca
      481 gcaatctgtc attaaaattc aaagaactaa acctaacggt aagactgaat acaaagtcat
      541 ctcaccgcta gaaattactg aattcaatga tttttctgat gcagtatcta ttaaatttag
      601 tagttcaatt atgcctttat taacgaactt agaagatcat tttacgcaat atacatttga
      661 tcaagtagtt aacttgacaa gcaagtatgc gatcagtttt tttcaattat tcactaaaga
      721 ttttaatctg tatgaagcaa atagagataa cttaacatgg agtacaaaat cacttgatag
      781 attaaaaaat cctgttttct ccattgcaga tttacgaaag aaatttagta ttgagaaaaa
      841 atataaagct tttcgagact ttgaaagacg tgtaattaaa gaaccgattg cccaactgaa
      901 taaatacact gattttaaaa ttgactatga gcttatcaag aagggtcata cttatacaaa
      961 cataaagttc ttgcttacac gtaccatgtc agttccggta ccttataagc aagaacaaag
     1021 agaccctgct tatttaaaag gcgcagaaga taaaacagag aaaatgaatc aatcgtactt
     1081 gaaagctatg aatagcaaat acactaaatt actaatcaaa aactttttga tcagttctgc
     1141 cgacttatgc gatcttaaac ttatgagccg acttcagaat aaagtttatc cgctttatga
     1201 tcgtttatcc aaagatagag gatttgaatc agttgtcaat cacctatctt acgttgctac
     1261 tcataaggag gattacacaa taaaaaatac tgttaaatat ctcgaaaaat caattacgag
     1321 ttatttgcct tatgtgaacc tttatgatta acaactgaaa aaatgcgtga aggaaggaaa
     1381 aacttttgaa aaaagatgaa ctgacaaagt acaatgagga gttcttagca acaattgata
     1441 tgaaaatgga tttaaagtcg tatgaacttt atcaattgct gttcagttat atctcaccca
     1501 caaagctaaa gaaaacaggc gtagtagatt tacctgttaa agcgattatt aattacatgg
     1561 atgttgatca aaatcttgaa acggaactaa aaaccatagt taacactttg caaagacaag
     1621 cagtttatga aatatcgaat ctagacaaga aatataagac gtatactact gtatctgcta
     1681 ttgatcggat tcattgggat ttagaagagc atagtgtatc tttcagtttt tcagaagatg
     1741 taattccctt aattgtctca atcaaaaaga agtatccgtt ctttgttttt aaagacttag
     1801 catcttttca aaaaaaatat agcatcgtgt tatacaaata tttggcgatg tattataaaa
     1861 aatatcttat cgccaaaaat aaaggagatt ttgagaaagc tgaaatatat aagaatcccc
     1921 tgattgaaat agttaaaatt cgtgagatta cgaaaacaga aaatgagtat aaaacaatat
     1981 cgaattttga tagacgtgtt ttaagggaat cagttgaaga aattaatgaa aaatcaatgc
     2041 tgaagattga ttttgctaaa gttagaaaag gcagaaatta caattttgct gtccagttta
     2101 atatttctag tgagtttgat gaaaaacctt atagagaaaa aaaattaggt taatgcaaaa
     2161 tatatcttac tcgtttgaag atgcttcaga cgtatgttaa gatatgtagt gccttgggag
     2221 caaggtatta atctccttta gaggttaatt agcttgtgat cgcctatcaa ttttttggta
     2281 ggcgattctt tttttgaaac caaaaagcaa aaattatttt ttaattagag aggtgcaatg
     2341 cgatgaaata ctttttttgt gcagtattcg aatggaaagg aaatgaatat gcagttaaat
     2401 tcccagattt tccagactta tatacgcatg gtgaaacttt agaagatgct tttgagatgg
     2461 cgcaagaagt attggaagga tacttggtgc ttttagagtt gcaagaaaaa gaaattccat
     2521 cgcctacgcc tgttcaagag ttaaatgcaa gaatcaagcg atctgagaat gttaatttat
     2581 ttgtcgtaaa agctaatacg aaagttgcta aagctcgaaa caagcaaaat tatgatcgaa
     2641 aatcagtgac tgtggaacac tatttaaatg ttttagcggc tgaagagaat attaatctgt
     2701 cgaaagcttt gaatgatttg ttgagagaaa agttgatttg atgtctctca gatgatcata
     2761 ttaagcaaaa acagcttgtt ttaggacgta tggatttaag aaagacaaat tatcaaagaa
     2821 tatattaaaa gctctcagaa gcgttctgag agcttttaaa t
//
LOCUS       DAFLVO010000164         2808 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.169, whole genome shotgun sequence.
ACCESSION   DAFLVO010000164 DAFLVO010000000
VERSION     DAFLVO010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2808
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.169"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            32..262
                     /locus_tag="L1U99_002954"
     CDS             32..262
                     /locus_tag="L1U99_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBN1213447.1"
                     /translation="MGFRTKRSLSSKKNWVYSQTIFYGGIVLISLLSSTLYSLNIIDV
                     STSNSISIIGIIIAAIITQLFLVFGEKKRSKK"
     gene            complement(353..718)
                     /locus_tag="L1U99_002955"
     CDS             complement(353..718)
                     /locus_tag="L1U99_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213448.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            926..1408
                     /locus_tag="L1U99_002956"
     CDS             926..1408
                     /locus_tag="L1U99_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213449.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSTFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1605..2495
                     /locus_tag="L1U99_002957"
     CDS             1605..2495
                     /locus_tag="L1U99_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HBN1213450.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT          957 a          447 c          550 g          854 t
ORIGIN      
        1 atggattttt gataggagta gaaattcaag tataggtttt agaactaaac gaagtttgtc
       61 ttctaaaaaa aattgggtat actcacaaac tattttttat ggaggaattg ttttaattag
      121 tttactttct tcaacacttt attctttgaa tattatagat gtttccacct caaattcaat
      181 atctattatt ggaatcatta ttgctgcaat tattacacaa ctgtttttag tgtttggaga
      241 gaagaaaaga agtaaaaaat agaaaaacta gtgatagttt tggtgatata agaaaaacat
      301 atatgtataa aaagaagaaa gtagcttctc tttgtacata tatggtttgt ttttatggat
      361 gccgagcttt tttataagat aaggctaccg cccataacga cccaaggatt tgtggaacta
      421 agtaaatacc tgcaagaagc aagatcagct gggtcggttt taaaggatga tagaagtaac
      481 gccattcagt aaaattggcg caaaataaat aggaagtgac agtagatata atattggcaa
      541 tgaataaaga tataatacgc ctgttccttt gaaaataata tccagcaaaa agagataaaa
      601 atatcaatgt gatgaacccg cttacggaat gataacgaaa atcaagcagt aaggcgaaat
      661 gcacataagg aacaaaagat aaaagcaacg gaaggttttt ccagcaagtt tttatcatct
      721 ttcatcacca cctaacaagt gttattattt tgttagtttt attgtaaatt gaatcctgca
      781 ataatcaatt actttttcat tatttctaga ttaaatgaat aaactctcat gccattatct
      841 ctaaaaaaaa agtttttccc cctaattttt ttagatagaa aattgtatag tatgatgaga
      901 gaaaaagtag tttgggggaa cgttaatgag aagaaaagca gtaatcgatc ggctttattt
      961 atttttttgg ttttttccta tcgttttgct accttttaca tgggtaaatg ctgttgtaca
     1021 aggtgcggag atattaggcc tgatccaagg aagcggattt gtggtttcta ggaattttcc
     1081 agctttgatt gttttctatt tagtgataag tgtaggtctc ttattaccaa aatctctgat
     1141 caatcactac aattggcagc tgctttactt ttcttgctta ttagtattta catctacgtt
     1201 ttctttgctg cctcgcttga ttatcggccc taatggtttg agcgagagtg gattgaagga
     1261 tttagcttat tcctccatgt atttcttgac gatcaaacca tggttctatt tagtaattgc
     1321 ctcatttatt cttgcaacat ttttttactt ctggacagaa atcaggataa aaagtgaacg
     1381 atctgtatct ataaaaaata actattgatg gtggatcatc agtaaaaaaa catatgagct
     1441 gcgtaaaatg catgtttctc atatgctttt tttattatta tgtaaagaat gcgaaaaacg
     1501 tttacatgat ttttacataa cttaactata tttttacagc aaccatacga gggatttaca
     1561 gtcgactgat aaactttagt tgtaaataag aaaggagcaa taaaatgaaa aaagtattgt
     1621 ttactctagg tatgatggga attcttttag ccggatgcgg ctcaggatca ggaaatacag
     1681 atggctctgc cacacaaaat aattcaagtg actcaaatga acaagtaaaa atcgttgcgg
     1741 taggttcgac agcattacag ccgttagtcg atgcagcaca agaaagcttt gtacaagaaa
     1801 atccaaatta tcaaatctct gtacaaggag gaggaagcgg aactggtttg agccaagtcg
     1861 aagctggagc agttactatc ggaaactctg atgtatttgc agaagaaaga gacggagttg
     1921 atgcttcaaa attagtggat cataaagtag cagtggtcgg gatggcacca atcgtcaata
     1981 aagatacaga tgtcaaagat atcaccaaac aggaattgat tgatatcttt acaggaaaaa
     2041 tcactaactg gaaggaagtt ggcgggaaag atcaaaaaat caacgtcgtg aaccgtgcaa
     2101 acggcagcgg tacccgcgcg acattcgaaa aatggggact ggatggtgct acccctgtgc
     2161 agtcccaaga acaagattca tcaggaacag ttcggcagct ggtaagtcaa acaccaggag
     2221 caatcagcta tttagctttc tcatatctcg atgattccac acaagcacta agtatcgacg
     2281 gtgtagaacc aaaagaagag aatgtagcag ataacagctg gggaatctgg tcatatgaac
     2341 atatgtacac gaacggaaaa ccttcccctg aagtccaaaa attcttagac tacatgatga
     2401 cagaagaaat ccaagaagga cctgtcaaag aattgggcta tttaccaatc acaatgatgg
     2461 aagtagaacg tgatcacgaa ggaaatatca aataactagc agataaacat gccacggtag
     2521 tcgttactat taaggaaaaa tcaactatgt ttccccacat atacattttt cctttaattg
     2581 tgaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt cagctgattg
     2641 aacaccgttt attcgaaaaa aagagctacg acatagaact gtcgtaactt tttttggctc
     2701 ttcgtcaaat cgtgttggtg aagacaaatt tgaataaaac ttagaccgat atgcggcgcg
     2761 ttctgtgcgc cgcatatttt tttagttttc aaagatcaga ccttgttg
//
LOCUS       DAFLVO010000165         2769 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.171, whole genome shotgun sequence.
ACCESSION   DAFLVO010000165 DAFLVO010000000
VERSION     DAFLVO010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2769
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.171"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(76..1875)
                     /locus_tag="L1U99_002958"
     CDS             complement(76..1875)
                     /locus_tag="L1U99_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBN1213451.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(1999..2595)
                     /locus_tag="L1U99_002959"
     CDS             complement(1999..2595)
                     /locus_tag="L1U99_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBN1213452.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT          977 a          522 c          480 g          790 t
ORIGIN      
        1 aaaaacgcat atacctgcgg tggcaggtta tgcgtttttt gttgtataaa gacttttttc
       61 attaacgatt tttgattagc cgactcccaa aacaaaattt agcagtttat ctgaataagt
      121 gatttcttca tctgtttgtt tcacactttc atttagtagt cccatctcat cggttatgat
      181 accatccaca ccataaaaca tcatgcgact catagcatct gaatcgttga ttgtccatac
      241 atatacttct tttccgtctt ggtgggcaga attaatgaag ttacggttga tcgtactata
      301 ttccattgtc agaaaatcag caggcgtcac agggggccca acaatattga aaggtaagat
      361 gtagcccaca taaaagtttg gttctgcttc ttttaaatct gaaacggttt ggtacgtcaa
      421 actttgcaaa atatgatggt tctctaagat aactttgcgg tatttatgga caaatcgttc
      481 gacaaggtca tccgaatctt ttttagaggt cttgatctca ataagtaatt tttggtttag
      541 cttatgtgct ttttccaaat aagaatcaaa agaacaaaca ggggcttgca ctccgttttc
      601 agtaactgta agatttgtca attctttcaa tgtaagatcc tgtggtgttc catttacccc
      661 tgttaagtga cgaagatttg catcatgcat cactacgaaa tgaccatctt ttgtttcctg
      721 aacatccatc tctacataat caggatgata gtctctgctt gttttttcaa gtgcttctaa
      781 agtattttgc gccccatttt gggtactcac acctctgtga gagacagtca ctggttttgt
      841 ctgaacagct gaagtcagat aatccatatt gtaaagacag acgccaatac cgaaaaaaac
      901 tgcaaaaaga gtcaaaccag tgtttttcag cgcagagaaa cgcaagttgg gggcttgtgg
      961 gataaaccac ttagggatct caggcaagaa gccttcgtca tccatgaaat caacaatgat
     1021 ataaaaaatc cctacggtag acatcacgat attgaataat aaaatccctt gtaaaagcgt
     1081 catagcaaac acagcgctga tcaatgcata gtctgggaaa aattgttcaa ccatactttg
     1141 tgccaaaata acaacgatat atcctaaaga agaaaggagt aaaatcgtac cgccaatcac
     1201 aataaattgg cccgtgatgg ccaaaagacg cgatttggtc aatgaccagc tttcccgaat
     1261 ggctgctcga aaaggacgat ctcgtagaat catttccggt aaagcaaaaa tcagtcgaat
     1321 cccaatatag ccaaggaaaa tataaacgag taaaaaggaa ctgacgatga tccaacgatt
     1381 agcaaaaata aaatccataa tgaaagcggg gatttttatt tttgacagta gatcagaatt
     1441 aaaacttaat ccgctgatcg gtagaatcaa taaaaaataa gcaaggaaaa acaaaaaagt
     1501 aatgggtctc actttcttca gctgaagtat cgtcaagtgt aagagttgct tcaaagagat
     1561 tggttctttc tttttaataa aaaaaacact catcaaaaga aaagtaaatt cgaaataaac
     1621 taacagtaaa atcgtcatca aaactacgat taacgagagt agaaccccag gatgttgaga
     1681 aaaaattgaa ggaatattgt cataagacaa atagtcaatt gcccctcggt gtaaaataaa
     1741 acgggtcgta ctgctcaata agggtaaaca aataaataaa ataaagccat gcatcagcaa
     1801 gacatcacgg aaataagctt gtgttccttt taaaaagtcc caagcattac ctaagctacg
     1861 tttcaaataa ttcatcctat cacctgctct tcacattgta gcgcaaatct aatgaaaaag
     1921 gaaagggtgc agtgtgtttt gcagaccctt tcccagattt aacattgtca atcaatgact
     1981 aattttacaa aataaatatt atccaagaag accacttaga tattgacctc cataaatcaa
     2041 ggccatacta tataagaaaa tcgacagtgg tttagcaatc aaaatgatta gtgtatatcg
     2101 tttcactgac atgtttgtca atccagccat caaacataac gcatcgtcag gagcaactgg
     2161 aagaaaaata gctagagcaa acagcttctc aaaacggttt tgattatcca gccagccaat
     2221 atatttgtta tatgtcttat cgctaatcat ggaaagtatg aatggctttc cataacgacg
     2281 ccctagcaga aaaatgataa tcgaaccaat gcagattcca atatagttat agataaatcc
     2341 agcataaggg ccaaatatca ggacaccagc tgcagtactg atccctccag gaatgattgg
     2401 aataactact tgcaggattt ggatgaagac aaaaataatc ggtcctaaaa tgatggaatc
     2461 acctactaat cctcttaacg cattcaaatc tttgaaaaca cctaaattaa taaaataaat
     2521 cgtcagcgcg attgataggc ctaatccgat aatggatatg aaatttatca gttttcgaga
     2581 ggcagcaata ttcattattc atcaactcct tagaggttct ttgttaacta tactttacta
     2641 gaaaagcaac taactgcgcc attttttgat atgacagaaa acaaacaatt ttgtaagttc
     2701 atcataagta taaaagattg atctcaaaaa aacatccaac taaagactta tttaataact
     2761 tgttttttt
//
LOCUS       DAFLVO010000166         2678 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.172, whole genome shotgun sequence.
ACCESSION   DAFLVO010000166 DAFLVO010000000
VERSION     DAFLVO010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2678
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.172"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            693..788
                     /locus_tag="L1U99_002960"
     CDS             693..788
                     /locus_tag="L1U99_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBN1213453.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(1090..1335)
                     /locus_tag="L1U99_002961"
     CDS             complement(1090..1335)
                     /locus_tag="L1U99_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213454.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
     gene            1680..1964
                     /locus_tag="L1U99_002962"
     CDS             1680..1964
                     /locus_tag="L1U99_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213455.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            1967..2383
                     /locus_tag="L1U99_002963"
     CDS             1967..2383
                     /locus_tag="L1U99_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213456.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
BASE COUNT          882 a          498 c          430 g          868 t
ORIGIN      
        1 ttccgttttt tcatccattc ctttcttccc cccttacaaa taaataataa cctttaacaa
       61 ccaactcgta aataggttgg ttgttattat acaaaaggat attagtactc agataaaaag
      121 ttgttagtac tcagataaaa agttgttagt actcagataa aaagttgtta gtactcagat
      181 aaaaagttgt tagtactcag ataaaaagtt gttagtaccc ttctgtatcc gttgggagag
      241 taaggctcaa ctgcccccta aaaagggttc taaaaaatct ttaaaaaata aataaaataa
      301 acgcgcgcgc gcgagcaaaa tttcccgcca aaaaatcacc cactttttaa aataaacagg
      361 ttcgcgcatg atattaaact gccaatctag ctccctatgg tcgctgtaag aaggagtgat
      421 cgctacgctc tcacatttta cttgcagcag tcgcctttag gctccttcgc caaaaataat
      481 tcattaggga ctcctttgtg gcgtcctgag agctcgtcta agccgttcta agacaagatt
      541 cgataaaaac tatgtccttc gttctaaagc gccttacagg cggtcagggc aagccctaac
      601 aaccccaagg caataaaaaa cttaggctta tttttgcttt tttattgtat aattgattgt
      661 cgcctatccg acagtcttgc gactggaagg aggtgtgttt cgtgttcact aactttattt
      721 gctcccttct tgttgggctt ttaagcgctt tgttcagtta ctggttgaat aaccgaaaca
      781 agaagtaaaa cttaattaag gcgactcagc ccacaaaaaa agccccagag aatccgacct
      841 ctctggggct ttcgtgtgtt tcgtgttcac ttatttgcaa tcaaattata acagaaataa
      901 atatttattt caaaaatatc ctacaaaagt ctaaaatccg taattatttc ttatatgcaa
      961 catttacaaa taaagtcgct ctgagagctc gtatttttcg atttaagacg ttttatttag
     1021 tttttggtgt atttcattgg tccaagctaa aaaactctta gaagcgattt tagagccatt
     1081 taaacccact taattatatt ctccatgaaa ttcgctccat gcgtcaaaag ctgcgtctga
     1141 aattccgccg tcttcgttca ctagttgcat taatttttcc aacgatcgtt ttctttcggg
     1201 tgtcatattt ttatattcca acaatttttc gtctgttaaa tcgaacttga ttgcttgaat
     1261 tgcttgctct aatttttcta agttttgaaa atattcgtaa ggaaattttt ccattttttc
     1321 tttctccagt ctcacaattt ttctagaaat aaaatcactt ctttgccgtc tatactctca
     1381 aaaaaaatgt cgtttgaaaa actaaataaa tttttgatcg tgcattttta aatttggtta
     1441 tcgattacac gtgcagcact cccccccgaa ttttaaagag cataaggaaa cgtgtaccca
     1501 ctttctaaaa aaagtgggta gataggctgt gcctatcacg tttctcagaa aaaaatttga
     1561 tatcactttt tcgccatcgt gggtagctta tgtatagcat tttggcaaaa aacagctata
     1621 caaatatagt atttgtatgg tatacataaa ttatacataa ttgcaaaagg agatttttta
     1681 tggacatttt agttcggaat attgatccaa agtttgttgc aacaatagac aaacgttgcc
     1741 aagaactcac gaataaaaca ggagaaaaat ggagtcgaaa taaatatcta aaagttttaa
     1801 tcgaaagtga ttttgaccgt caacttacga cttacaaaaa agaccaattc gatttattgc
     1861 tcgataaatt tattgctatc caaacagaaa atactcaaat attaagcgag tatgtctaca
     1921 caaataatca aatcattgaa atgcttatcg gaggaatgat ataaccatga gaaaaacttc
     1981 tgtccaaaaa catgttactt tgtaccctag tcatgttgac gttttagatt ccatcatcga
     2041 aaaaaatcca gatatcaata actactcgga agccattcgc tttttatgta tgagttatga
     2101 acccgatacc aacacgacca ctaccagcaa tcaggcaaaa ctaaatgcta tgggaaaaga
     2161 aatttccatc atgactgaaa tcatcgcaga atttgctgat ttatatctaa aagatacagg
     2221 cgttcttatt ggcacaaatt ctaaagtata tcaagaagtg aaagaaaaaa tcgaagctaa
     2281 actaaatcca tcaaatcgaa atcgaccaaa gaatcatcaa aaagaaacca gtcaaacagt
     2341 cacttctaga aatttcgacc caacaaattt tctaaaacga taaaaaacag ataggagtta
     2401 ttcctatctg ttttttattt agaagcccca tacaatatgc tagaatgtac tagcaatctt
     2461 agtcggttgt aagggacttg tctacttgct taatgtaagg ggggcgagtt cttttttatt
     2521 tattcttcta accagttacg cagagaaatc tttggcaaat ctgacgttag gcttgaaaaa
     2581 gtaaattcta atttggcgat tttattgccc ttttttgctt ttatttttgt gactttaaga
     2641 tcattgaagt atttttttag ttctcgtaat gcaggatt
//
LOCUS       DAFLVO010000167         2520 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.173, whole genome shotgun sequence.
ACCESSION   DAFLVO010000167 DAFLVO010000000
VERSION     DAFLVO010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2520
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.173"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..1097)
                     /locus_tag="L1U99_002964"
     CDS             complement(<1..1097)
                     /locus_tag="L1U99_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBN1213457.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIEGKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKVRGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRYLPSK
                     DYKEVCRDMKKFYSASSLNAAHAAFDSFQNRWSHYSGAVDVCKRNFSHVEQLFDYGSA
                     IRKIMYTTNAVESIHSSFRKVTKKGVFSNENA"
     gene            complement(1227..>2520)
                     /locus_tag="L1U99_002965"
     CDS             complement(1227..>2520)
                     /locus_tag="L1U99_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1213458.1"
                     /translation="LSLISLSIKDATDRASKETFANITNSFSMEINRQVNPGTPRGGG
                     NVKGEDIKKISQTDSIDSYVKRINSVADLVDYDIIETQETLANQSPERAKNFKRTVML
                     TGVNDSTKETKFVSEAYKLVEGKHLENEDKNKILMHKDLAEKNNLKVGDKIKIKSNLF
                     DADNEKGADETVEVEIKGLFDGHNSGGVSAAQELYENTLITDIHTAAKVYGNTEDTAV
                     YQDATFFVKGDKNLDSVIKDLGKLDINWREYNLIKSSSNYPALQQSISGIYSISNKLF
                     FGSLIFAGVVVSLLLFLWMNARKKEIAVLLSLGISKLEIFGQFLIEMVFISIPAFVGS
                     YFLAQYTADKLGNNILNKVTGDIAKQIAKQSASSQLGGGAEAEGFNKTLSSLDINVLP
                     KFMIYVVIFMSLVLLVSLIISSFNILRRNPKELLIDNN"
BASE COUNT          766 a          486 c          371 g          897 t
ORIGIN      
        1 gcattctcat tagagaacac tccctttttt gtgacttttc tgaagctaga gtgaatactt
       61 tcaactgcat tagtagtgta catgattttt ctaatggcgc tgccataatc aaagagttgt
      121 tcaacatgag aaaagtttcg tttgcataca tctactgcac cagaataatg agaccaccga
      181 ttttgaaaac tgtcgaaggc agcgtgtgca gcgtttaaag aagaagcact gtagaatttt
      241 ttcatgtctc gacagacttc cttataatcc ttacttggga ggtatcgtaa cgcatttcga
      301 acaagatgaa caatacagcg ctgcacaatg acagaaggaa aaattgcttt tgcgccttct
      361 ttgagaccgg aaacaccgtc catcgaaatg aaaaaaacat cttctacacc acgtactttc
      421 agttcatcaa atacttgcat ccagcgattt ttagattctg tttgattgag ccataggcct
      481 aaaatctcct tgtttccttt aagatcatag ccaagaatgg tgtacacagc atattcttta
      541 gcttcatagt tttcgcgtaa agtgacgtac atacaatcaa cgaatagaaa tgcataacac
      601 ttggctaatg gccgagcttg ccattcttcc aattcaggaa ggacggcatc cgtgatatca
      661 gaaatcattt cgtgggaaat atcaaagccg taaatatctt caacggttgc ggcgatatcg
      721 cattgactca ttcctcgtgc atacatggaa agaaccttac cttcgatgtc ggagacatct
      781 cgttttctat taggaatcaa ctcaggttca aaagaagcct cccggtctct gggaacatca
      841 atgtttactt taccaaagct cgttttaagc gtcttattgc cataaccgtt tcgtcgattg
      901 tcatgtttct ttggctcttt agaatgggcg tcatacccta aatggttatt caattctcct
      961 tgaagcattt tttcaaataa gggaccaaac acatctttta aaacatcttg catatcctct
     1021 acagattcgg gttgataagt attcaaaatg gattcagcta acttctcagc atcaggattt
     1081 cttttctttc tagccatcgt gtaatcacct cttgatctta ttttagaaaa ataaaaaccg
     1141 tgaagcaacc acccgcctag gattgatggt tacttacacg gtttatatta cactctcatt
     1201 tttggtgcta aaaagcaccg aaaattttaa ttattgtcaa ttaataattc ttttggattc
     1261 cttcttaata tattgaatga agaaataatc aatgatacaa gaagtactaa actcataaat
     1321 ataactacat aaatcatgaa tttaggtaat acattgatat ctaaacttga taatgtcttg
     1381 ttaaatcctt cagcttctgc cccaccacct aattggctag atgcagattg tttagctatt
     1441 tgtttagcta tatcaccagt aaccttattc aatatattat tcccaagctt gtcagctgta
     1501 tattgagcta agaaatagga accaacgaat gcggggattg atataaatac catctcaatt
     1561 aggaattgac caaaaatttc taattttgat atacctaatg atagtaatac tgctatttct
     1621 ttctttctag cattcatcca taagaataat aataatgaaa ctacaactcc tgcaaatatt
     1681 aatgagccaa aaaataattt atttgaaatt gagtaaatac ctgatataga ttgttgtaat
     1741 gcagggtaat ttgatgaact tttaatcaaa ttatattctc tccaatttat atctaatttc
     1801 ccaagatctt ttattacact atcaagattc ttatcacctt ttacaaagaa tgttgcatct
     1861 tggtatacag ctgtatcttc ggtattacca taaactttag cagctgtatg aatatcagtg
     1921 attaatgtat tttcgtatag ttcttgtgct gcacttactc caccgctatt atgcccatcg
     1981 aatagacctt taatttctac ttctactgtt tcatctgcac ctttctcatt atcagcatca
     2041 aataaattag attttatttt tatcttatct ccaactttaa ggttattttt ttcagctaaa
     2101 tctttatgca ttaagatttt atttttatct tcattttcta aatgctttcc ttctactaat
     2161 ttatatgctt ctgatacaaa ttttgtttct tttgttgagt cgttaacccc agttaacata
     2221 actgttcttt taaaattctt tgctctttca ggtgattgat tcgcaagagt ctcttgagtt
     2281 tcaataatat cataatcaac taaatctgca acactgttta ttctttttac ataggagtct
     2341 atactatctg tttgagatat ctttttaata tcttcacctt ttacatttcc cccacctcta
     2401 ggtgttcctg gatttacttg tctatttatc tccatagaaa aactatttgt tatattagca
     2461 aatgtttctt ttgaagctct gtccgtagca tctttaatag ataaactaat gagacttaaa
//
LOCUS       DAFLVO010000168         2490 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.174, whole genome shotgun sequence.
ACCESSION   DAFLVO010000168 DAFLVO010000000
VERSION     DAFLVO010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.174"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..527
                     /locus_tag="L1U99_002966"
     CDS             <1..527
                     /locus_tag="L1U99_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBN1213459.1"
                     /translation="RINRNNTTAFKIFRAIINRCLRMIKLPPKIRHHKFDLYHGSQWW
                     ALSKECLTELIQMYEQNQQDYLNFKIGMFAPDEKFFHTLFFNSSFKNKNVIGGPDLPL
                     ELKNIEETTLQTSKLANIHIIDPSMNKWFDERDIDQIKESEKLFVRKVKSDYSDKLLN
                     RIDKEILKVGNIDE"
     gene            520..1947
                     /locus_tag="L1U99_002967"
     CDS             520..1947
                     /locus_tag="L1U99_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBN1213460.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
     gene            1949..>2490
                     /locus_tag="L1U99_002968"
     CDS             1949..>2490
                     /locus_tag="L1U99_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213461.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKI"
BASE COUNT          878 a          291 c          394 g          927 t
ORIGIN      
        1 ctagaattaa taggaataac acaactgcat ttaaaatttt tagagctata attaatcgtt
       61 gtctgaggat gattaaactt cccccaaaaa ttagacacca taaatttgat ttgtatcatg
      121 gttctcaatg gtgggctttg tcgaaagaat gcctaacaga attaatacaa atgtatgaac
      181 aaaatcaaca agactacctg aattttaaaa taggtatgtt tgccccagat gaaaaatttt
      241 ttcatacact tttttttaat tcctcgttca aaaataaaaa tgttattgga ggaccagatt
      301 taccacttga attgaaaaat attgaagaaa ctactttaca aacttcgaaa ttagcaaata
      361 ttcatattat tgatccttcc atgaacaaat ggtttgatga aagggatata gatcaaataa
      421 aagaaagtga aaaattattt gtaagaaaag ttaaatcgga ttactctgat aaactattaa
      481 atagaattga taaagaaatt ttgaaagttg gaaatataga tgaatagaat agtacctgtt
      541 ttagagaaga gtttattaag tcgagatgcg tttcgagtaa taaatttaat catttgtctg
      601 ctttatttta tgcctagtac ttttaatgta actaatatcc cgatgaaaat agcttttgct
      661 tggggtggaa ttatagtttt gtatgaggtt tttataaaga aaaatttttt taaaatgcgt
      721 ttttcttggc tactgattgg agcaatgatt agttttatct taactataat cattaacaga
      781 gaaaattttt taattccatc tatttataat tttggatatt tgctgattac tttgatagta
      841 atttttcctg cagacttttc acaaagtgaa gaggaaaaaa agaaaaaaat ggtgtatttt
      901 aataatgttt tcattatcat aattttttta gctgcgctaa tatctatcta tcaatttatt
      961 tttttgattt cttatcatgt cccaacagga acgccaggat tacttgcaag acaaggtttt
     1021 attgaacatc ggttatttgg tgtctataca agtccaaatg ttggagctat gtttggatat
     1081 acttctatta ttttaagttt aattagtgta ttaatttcaa aaataacaaa aacgattcgt
     1141 gttttttata tgatgaattt tatcgtacaa atattttata ttacactttc ttcgtctaga
     1201 ggtgcccagg tagtaatttg ttctttttta gtattatttc ttttgttgtt tgccaattca
     1261 aaatttagaa agagcattag agaagtacta cctgtaaaaa tcaaatggat ggtaagcata
     1321 ttattagttc tattggtata tttttctttt ggtactaatt atgctaagga ttttttagca
     1381 acaattcctg tatcgattga tagaaaagta gaagttatag agtcaaatga atcagataaa
     1441 actccacttc cagaaaaaga agtaatatta cagcattcta gtgataactc cgaaatttca
     1501 gctggtcgtt ttacgatttg gaaagctgcg cttaaagtta taagaccaac tttgttattt
     1561 ggttatggag agaccgattt ctatgggaat agcgatgcaa aatttttgaa aaaagtagat
     1621 cttgatacta cagatgtgaa tgaactaaaa agagcacatg gaaacatgca taatggattt
     1681 cttcaagtac ttgtatcaag tggtataatt gcttttatat gtatctatgc tttctatgtg
     1741 ttaaatatct ttagtttact caaaacattt tttagaagta aagtgaatta tgcgtttctt
     1801 ggtattgttt taatttttat actatctatt tttatagatg aaatggtgga ggctcatgta
     1861 cttttcaata agcgcgatgt catttcaatt gttttctggt attatttggg aagcatttct
     1921 tacttgtatt taaaaaagga gaattaatat gaagacagct ttcattgctt ggactccttt
     1981 acatttgatt aatatattaa atgtttatca aaatttttac cgagaatcaa aaggagattt
     2041 atttatttat tctgaatttg aaaacgctag aagatatagt gagcgtataa aagaattagg
     2101 gctatttaat gatgttgttt ttgtgaatca ccggaaaatc ggttcttcct ttaaacgtaa
     2161 aattaacttg ttaactaacc ataatcaatt tttctcggat gatttatccg tttatgatga
     2221 aatttttata cagggggaaa attatttcac aaaaatactt ttctccaatg tttacaaaaa
     2281 aaatccagat gtaaaactaa attatataga agatggtttg ggtacttatt tgaagaagag
     2341 tatattttca acaagtaaaa acgttcaaag agtttttaaa atattaaata aaaatagcat
     2401 cttcaaaaaa aaaattgacg attattttgt ctattgtccg gaattgttac tttatgatgt
     2461 aaaaaatata aaaaaaattc ccaaaataga
//
LOCUS       DAFLVO010000169         2437 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.175, whole genome shotgun sequence.
ACCESSION   DAFLVO010000169 DAFLVO010000000
VERSION     DAFLVO010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2437
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.175"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            78..767
                     /locus_tag="L1U99_002969"
     CDS             78..767
                     /locus_tag="L1U99_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein"
                     /protein_id="HBN1213462.1"
                     /translation="MRTHYIYLEDKIVDEIPAKSREQARKLFIEKYKEINGDSEVPKV
                     VVTVRKRQTKKRSTFHVSPDIYNLIERHRSEDNISISQYIATVIDELISGKYDYAFDF
                     EGEKDYKSVAVFQSDFEKLKNYAGRRNVNFARLLEEFYSEELGVGNEYKRETYAKLSH
                     KLSQALKEVTEVKAELDAKLEEVKKYQTERKNNMKNQVEFDEQKEFEKARKRYNKIMN
                     ELSYEHLTVHE"
     gene            804..971
                     /locus_tag="L1U99_002970"
     CDS             804..971
                     /locus_tag="L1U99_002970"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213463.1"
                     /translation="MVNEVETLLASFFENGHVNDEWRKEEPKRVNAYIARLKRFIDKY
                     KENSDKFSKDK"
     gene            991..>2437
                     /locus_tag="L1U99_002971"
     CDS             991..>2437
                     /locus_tag="L1U99_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213464.1"
                     /translation="MPEIEGIFSPKIGKKQLDFSSFPSVNRDYNLGDEVQILNIDFKE
                     LDFAVAVSNKPKALERVKKIYQENDQNIKNMIKKYRRDNSKVEDVLFNGTAKHDLNVY
                     MALGVALYCNSINQTDILVNIVRNSYQKILKISSETNPYYAMKYLGDNLLNDKKLMHN
                     TEELLSNLAAINFLFKTGSEDYFIDNVLKGAYGTAFYPLYNMKQHKAEQKDNKLEIKK
                     MKELLGIGFVKPNSKVTIASLATTNNDGKIVNGFDDSDIDILSKSYFSLYGDFADLMG
                     IDSYLVNNFEIKGSELNDIVYFVLISLYAIDQNTEYRQIDYLLVFYSLLYQFVLTRLF
                     KNAKEELILNSDYEIAKQIASIRKENKSEVIKLRKELSIASKENGRLESLVKSAKKEE
                     ELLKQEIKELKGIRKELEQLRFENKVLKQLQEQEHRQSLNGKTEEPSLSEMIAYLKHK
                     NILLVGGHVNFQNKLTELLPNIKMFDVSENNG"
BASE COUNT          989 a          286 c          473 g          689 t
ORIGIN      
        1 tttgcaatgt ttaagagtaa acaaggtaag aactaagatc atgaagattg agagtaaaga
       61 agatagagga cgaatgtatg agaacacact atatttattt agaagataaa attgtagatg
      121 aaattccggc aaaaagtcga gaacaagcta gaaaattatt tattgaaaaa tacaaagaga
      181 tcaatggaga tagtgaagtt ccaaaagtgg tcgtaacagt tagaaaaagg caaacaaaaa
      241 agagaagtac gtttcatgtc agccctgata tatataatct tatagagcga catagaagtg
      301 aagataatat ttctatctct caatatattg ctacagttat tgatgaattg atttcaggaa
      361 agtatgacta tgcttttgat tttgagggtg aaaaggatta caaaagtgtt gctgtctttc
      421 aatctgattt tgagaagcta aaaaactatg ctggcaggag aaatgttaat tttgcaagac
      481 tactagaaga gttctactcc gaagagttgg gagtaggaaa tgaatacaag agagaaactt
      541 atgcgaaatt gtctcataag ttatcccaag cgcttaaaga agtgacagaa gttaaagcgg
      601 aactagatgc taaacttgaa gaagtgaaaa aatatcaaac agagaggaag aacaacatga
      661 agaatcaagt ggaatttgac gaacagaaag aatttgaaaa agcaagaaaa cgctataaca
      721 aaattatgaa tgaacttagc tatgaacact taacagttca tgaataattg agtgagggta
      781 cagaaaaata tacgatcgca gatatggtta atgaagtgga aactctttta gcttctttct
      841 ttgaaaatgg tcacgtaaac gatgaatggc gaaaagaaga acctaaaagg gttaacgctt
      901 atattgctcg attaaaaagg tttattgata aatataagga gaatagtgac aaattttcta
      961 aagataaata aggagagagt gtgattacat ttgccagaaa tcgaaggaat attttcgcca
     1021 aaaataggta aaaaacagtt agatttcagc agttttccga gcgtaaatag agattataat
     1081 ctaggtgatg aggtacagat actaaatatt gatttcaaag aactagactt cgctgttgct
     1141 gtttccaaca aacccaaggc attggaacga gtgaaaaaaa tataccaaga gaatgatcaa
     1201 aatatcaaaa atatgatcaa aaagtataga cgagataatt caaaagttga agacgtttta
     1261 ttcaacggta cggcaaaaca tgatttgaat gtttatatgg cattaggagt ggctttgtac
     1321 tgtaattcaa ttaatcagac agatattttg gttaatatcg tgaggaatag ctatcaaaaa
     1381 atattaaaaa taagtagcga aacaaaccct tattatgcaa tgaaatatct tggggataat
     1441 ttattaaatg ataaaaaatt gatgcacaac actgaagagc tgttatctaa tttggctgcg
     1501 attaactttc tattcaaaac aggttctgaa gattatttta tagataacgt actaaaaggt
     1561 gcttacggaa cagcatttta tccgctttac aatatgaaac agcataaagc cgaacaaaag
     1621 gataacaaac ttgaaattaa aaagatgaaa gaactattag gtataggatt tgtaaaaccc
     1681 aattcaaaag tcactattgc ttcgttagca actactaaca atgatgggaa aatagtaaat
     1741 gggtttgacg attcagatat agatatattg tcaaaatcat atttttcttt gtatggagat
     1801 tttgcagatt tgatgggtat tgatagttac ttagtcaata attttgagat caagggtagc
     1861 gagctgaatg atattgtgta tttcgtttta atctctctat atgcaattga tcagaatacc
     1921 gagtaccgac aaattgacta tttgctagtt ttttatagtt tgttatatca gttcgtttta
     1981 actcggttgt ttaaaaatgc taaggaagaa ttgatcctga attctgatta tgaaatagca
     2041 aaacaaattg caagtattag aaaagaaaac aaatctgaag taatcaaatt aagaaaagaa
     2101 ttaagtattg cgagtaaaga aaacggtcgg ttagaatctt tagtcaaatc ggcaaaaaaa
     2161 gaagaggaac ttttgaagca agagattaaa gaattaaaag gaatcagaaa agaacttgaa
     2221 cagctgaggt ttgaaaataa agtattaaag caattgcagg agcaagaaca tagacaatca
     2281 ttaaatggta aaactgaaga gccttcactg tctgaaatga tagcttatct aaaacataaa
     2341 aacattcttt tagtgggagg acatgtaaat tttcaaaata aattaactga actattacca
     2401 aatattaaaa tgtttgatgt aagcgaaaat aatggaa
//
LOCUS       DAFLVO010000170         2399 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.176, whole genome shotgun sequence.
ACCESSION   DAFLVO010000170 DAFLVO010000000
VERSION     DAFLVO010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2399
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.176"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            207..2069
                     /locus_tag="L1U99_002972"
     CDS             207..2069
                     /locus_tag="L1U99_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1213465.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2399
                     /locus_tag="L1U99_002973"
     CDS             2069..>2399
                     /locus_tag="L1U99_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1213466.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          715 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataatt
//
LOCUS       DAFLVO010000171         2357 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.177, whole genome shotgun sequence.
ACCESSION   DAFLVO010000171 DAFLVO010000000
VERSION     DAFLVO010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2357
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.177"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            239..886
                     /locus_tag="L1U99_002974"
     CDS             239..886
                     /locus_tag="L1U99_002974"
                     /inference="COORDINATES: protein motif:HMM:NF014505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBN1213467.1"
                     /translation="MPNKNYRVYKRGTIVYVDFGVNVGYELSGNHFAIVLNNKDNSKN
                     GVVCVVPISSKKKSNYVSVGKILEVASIKQFISQADKLKEKLRIIILLSLNRGIIDES
                     DLNSFIKDIEAKGEKLSVEEVEKRAVKHNLVCETREQVIKEIKSLSEDMVKYQKVFNC
                     YKKYTQESYVMPLNIQTISKNRIRRINKFDPSGNMKAPGNVLNEVDESLKKYFTK"
     gene            1169..1242
                     /locus_tag="L1U99_002975"
     tRNA            1169..1242
                     /locus_tag="L1U99_002975"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1203..1205,aa:Ile,seq:cat)
     gene            1788..>2357
                     /locus_tag="L1U99_002976"
     CDS             1788..>2357
                     /locus_tag="L1U99_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HBN1213468.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNG"
BASE COUNT          839 a          333 c          434 g          751 t
ORIGIN      
        1 gaggggaagt acataatgca aatttgtcca taacttattg attatcttgt aaaaatgcgg
       61 taatttaata gttagtgaga agaggtgctt aattatagtt aaaaaagagg aaatagaagc
      121 agcatgtaac caagcaaatg ttaggtttat tggagaagct ttatctggat atcctaagta
      181 taaatactta cacaactggt tacaaagtaa aagtttttat cttaataaag aaagatgcat
      241 gcctaataaa aattataggg tttataaaag aggaactatt gtatatgttg attttggggt
      301 gaacgtgggt tatgagttat ctggtaatca ttttgctatt gttttaaata ataaagataa
      361 ttcgaaaaat ggtgttgtat gtgtagtacc aatctcttca aaaaagaaaa gtaattatgt
      421 atctgtagga aaaatattag aagttgctag tattaaacaa tttataagcc aagctgataa
      481 attaaaagag aaacttagga taattatttt actttcatta aatagaggca tcattgatga
      541 aagcgatttg aatagtttta ttaaagatat tgaagctaaa ggtgaaaagc tttcagtgga
      601 agaagtagaa aaacgagctg taaaacataa tttggtttgc gagacaaggg aacaagtaat
      661 taaagaaata aaatcattat ctgaagatat ggtaaaatat cagaaggtgt ttaattgcta
      721 caagaaatat acacaagaat cctatgtaat gccacttaat atccaaacga ttagtaaaaa
      781 tagaattaga agaattaaca agtttgatcc ttctggaaat atgaaggcac ctggaaatgt
      841 cctcaatgaa gtagatgaaa gtttaaaaaa atattttaca aagtaaacga tatttttgtt
      901 gacatttttc tgttcgttag ttaccatgta gttatagaag gacgtaagcg cctattttta
      961 atgtacacat cgggacgtat gcgcccacat agaaacatag ttgagagaca tctatatggt
     1021 gtctcttttt ttattaatat gcaaaaaagt ctagtttttt caataatatt tatgtaataa
     1081 taaattagcc accacaacaa agaatgaaac ccattattat ctagtctatg tccattcttt
     1141 ttgtttgcag tagttgtgat ggctttccgt actcttagct cagttggtta gagcagacgg
     1201 ctcataaccg tccggtcgta ggctcgagtc ctacagggta catactctaa gtgatttaaa
     1261 ttgcgaataa aatataaaaa tgactcccct tttgactccc ccaagcagta tatggatgtc
     1321 tctaaaagtt gtttttttag ataataaaaa gctgataata agcgaaaaac acttaaaatc
     1381 agctttaaac cctattctcg aaatccggcg aaccggctaa taccggcgcg caggttcaaa
     1441 tcctgtacct tccttatatc aacgattaga ggttgtgaag aagctgtcct gcatcaagta
     1501 ataagaacgg ccaaacaaaa atagcttttc ctattttttc gtttgattgg gcttattacc
     1561 gcagatgcaa gcttttgaac accgtttgtt cggaataagg ggctgtgaca agacttttgt
     1621 cacagcccct tattgttgta cttttaacct acaatatttt ttgattcccc ctgagtacta
     1681 ttttttataa atgctagtaa atcaatcttc tttggccttt ttttgataaa aaaaatacta
     1741 gatgtaagat aaaagtgtaa aaacgatttg ttttaggagg ggaaacgatg tgtaccgcaa
     1801 tcacttatgc aacgaaagac cattattttg gaaggaattt tgattatgag atgtcttata
     1861 atgaagtggt cactattact ccaagaaatt atcgtttcga ttttagaaag gtaaaaaatt
     1921 tagataaaca ttatgcaatg ataggaatag cagctggggt atccaactat ccactctatt
     1981 atgaggctac aaatgaaaaa gggttgagta tggcaggact gaattttcct ggcaatgctg
     2041 attataaaga attacaagaa ggaaaagata acgttgcacc atttgagttt attccatgga
     2101 tactagggca atgctcaacc atagacgaag ctaaagaatt attggctact atcaatctag
     2161 tcaatatcga ttttagtgaa aaactaccct tgtcaccttt acactggtta ttagctgata
     2221 aagaaaaatc gatagtaatt gaaagtatga aagatggact tcatttatat gataatcctg
     2281 tcggtgtgtt gacaaataat ccgccatttg attatcaatt atttaatctg aacaattatc
     2341 gctcgctatc aaatgga
//
LOCUS       DAFLVO010000172         2355 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.178, whole genome shotgun sequence.
ACCESSION   DAFLVO010000172 DAFLVO010000000
VERSION     DAFLVO010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.178"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(552..809)
                     /locus_tag="L1U99_002977"
     CDS             complement(552..809)
                     /locus_tag="L1U99_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213469.1"
                     /translation="MINEDFRSENKMIDISLIEKLLFSNKYTAKELATRWQISESAIK
                     AYRQNKGSVGWRDWKGISIGKAEDIMKREGFQADNDSKKVE"
     gene            complement(812..1036)
                     /locus_tag="L1U99_002978"
     CDS             complement(812..1036)
                     /locus_tag="L1U99_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213470.1"
                     /translation="MNQRRRKRLEEISERLSELKDELEVIQEEEYKENIPKNLQGSER
                     YEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            complement(1209..2252)
                     /locus_tag="L1U99_002979"
     CDS             complement(1209..2252)
                     /locus_tag="L1U99_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBN1213471.1"
                     /translation="MKKFLVGILFTMGLVLLSPSVSAESSISMYRMYNPNSGEHLYTR
                     SVGERDNLKRYGWHYEGVAWQAPTSGTPVYRLYNRYNGEHFYTVDAGERDKISHTGWT
                     YEGVAFYSYNGANRVPVTRLYNKYVNWHHYTLDQNEKNVISKQGWKIEGTGWYAMPNS
                     VPNPTPAPSTEKVLNVPVVWQGNTMLCEGASLLEGLHYKGVATNQSLTSFVNYMPKAN
                     DNNPYHGYSGEWRHNVNGTYQGMMADPVVKWAKNVGGNAVNITGSGTNGIKNEIRNGN
                     PVVTWITYNYATPEFKQMPWGRAVWNGHVVLVDGFRNGAYHVVDPVFGAKWINASTYE
                     RAFNVTGMAVAVR"
BASE COUNT          635 a          502 c          332 g          886 t
ORIGIN      
        1 aatttgaagc tattattcaa ataaagtaac aagatcaata tatgtttgtc agaaattctg
       61 acaaatctat tactttttag atactcacca atggcttcac ttaactcttt gaagccattg
      121 tattttcccg ataaaaatgt cgtaacatta tcttctctct ttttcctatg gtgtgaactt
      181 accctgaaat aatagagtct attctcattt aatattgaaa aataaatact ttcagttgtt
      241 tgtgagcatt gtatatagtt gaaatgatat ccatctggca tgactttttt aactgtattt
      301 tgtactagct ctgaccacct tttgttagta gtcatatatt tttttccatt aaaccaaaca
      361 taaatatctt ttttaaaaat tttgttcccc ccctattgcg ttttctttga cattaaagcc
      421 ctttgttttc atcacattcg tatagcccta gccactcata acctgatgct tttgcgaagt
      481 ttatttaaaa gtgttttcct ttgtaatcta cctttcccct cgtcctggta cttttcttgg
      541 cgactattaa actattcaac ttttttagaa tcattgtcag cttgaaatcc ttcacgtttc
      601 attatgtctt ctgcttttcc aatgctgatt cctttccaat cacgccatcc tacgcttccc
      661 ttattttgac gataggcttt aatagctgat tcggatattt gccatcttgt agccaactct
      721 ttggctgtgt acttatttga aaaaagtagc ttctctatca gtgaaatatc aatcatttta
      781 ttctcactcc tgaaatcttc attaatcatc tctagctagc tatatcttca atcaattcta
      841 atatgtcgga taaaccatca acagcttctt caagttgatc aacggattct tctgcttttt
      901 catatctttc tgatccctgt agatttttag gtatattttc tttgtactct tcttcttgaa
      961 ttacttctaa ctcatccttt agctcggaaa gtcgctcgct tatttcttct aacctttttc
     1021 ttcttctttg gttcatcaaa atcacctctt cgcataatct ctacgatttt aatataccac
     1081 ttttgtgtac tacattcaat attttttgtt atagattcgt attacaaaaa tttcctctaa
     1141 aaaaataaga gcctatttac catttcagta attaagctct tatttcattt agttgataat
     1201 tctatcaatt aacgtacagc aaccgccatt ccagtcacat taaatgctct ctcatacgtg
     1261 cttgcattga tccattttgc gccaaataca gggtcaacaa catggtatgc accatttctg
     1321 aagccatcca cgagaactac atgtccattc catactgcac gaccccaagg catttgtttg
     1381 aactctggcg tagcatagtt ataagtaatc caagttacaa ccggattacc attgcgaatt
     1441 tcattcttga ttccattcgt tcctgaacca gtgatattga cggcattacc gccaacgttt
     1501 tttgcccatt taactactgg gtcagccatc atgccttgat acgttccatt aacgttatga
     1561 cgccactctc ctgagtaacc atgataagga ttattgtcat tagcttttgg catatagttt
     1621 acaaaactgg ttaagctttg atttgtggct acacctttgt agtgtaaacc ttctaataaa
     1681 gaagctcctt cgcataacat tgtatttcct tgccatacaa caggaacgtt caacactttt
     1741 tcagtgcttg gagcaggtgt aggatttggt acgctgtttg gcattgcata ccagcctgta
     1801 ccttcaatct tccaaccttg tttactaatt acgttctttt cattttgatc taacgtgtag
     1861 tgatgccaat tcacgtattt gttatataaa cgtgttacag gaactctatt tgctccgttg
     1921 taggaataga acgcaacacc ttcgtacgtc catcctgtgt gtgaaatctt atctctttct
     1981 ccggcatcaa ctgtgtaaaa atgttcaccg ttataccgat tatacaaacg ataaacagga
     2041 gtaccacttg ttggagcttg ccatgcgaca ccttcgtaat gccatccata acgtttcaga
     2101 ttgtctcttt ctccaacgct tctagtgtat agatgctctc cgctattggg attatacata
     2161 cgatacatgg aaatagagct ttctgctgaa actgaaggtg ataataatac tagccccatt
     2221 gtgaatagaa ttcctactaa aaattttttc atttgatttt accccttttc attttttatt
     2281 gtcattattg catgaaaatt attcgtaaga ttgccaatta cataaacgat tgttttaaga
     2341 tcataatcgt tgttg
//
LOCUS       DAFLVO010000173         2270 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.179, whole genome shotgun sequence.
ACCESSION   DAFLVO010000173 DAFLVO010000000
VERSION     DAFLVO010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2270
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.179"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            191..445
                     /locus_tag="L1U99_002980"
     CDS             191..445
                     /locus_tag="L1U99_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBN1213472.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            446..763
                     /locus_tag="L1U99_002981"
     CDS             446..763
                     /locus_tag="L1U99_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBN1213473.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1322..2257
                     /locus_tag="L1U99_002982"
     CDS             1322..2257
                     /locus_tag="L1U99_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213474.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          823 a          307 c          429 g          711 t
ORIGIN      
        1 gatgttaacg gaagtgtatg gtgagtagtt cactcgtatt ttgatatcgt ttgtatatgt
       61 tttcagcgtt ctaagtggct tattttgtcc aataataata tggagtggaa tcccttaaga
      121 aacaccgttg gcaattgttg ttataacatg ttataattta ttcatcaaaa actaaaagga
      181 gtgtgataac atgggaaaag aactaaaggt tagaaagatc ggcaatagcg tgggagtgat
      241 ccttccaagc tctcttggat taaaaagcgg agacattatc caagccaaac aagaaggcaa
      301 cttattcata ttagatacta ctcaaatagc aaaagaacac gatcgcaaat tgattgaaga
      361 aagtttccaa gactttgaga aaggtttaac agtttcagaa attgaaatgg taaaagcttt
      421 cggaaaatac ggctggagtg aatagatgaa agagtacacg ctagtttatt ctaaaagttt
      481 tcagaccagc cttgaaacga taatagaaga atgggaaaat gagcttgctc tttctccagc
      541 cagcataaaa agatttgtag gtgcgatcca gaaggcttta gaactaacca aaaattttcc
      601 aactatgcat gaggaagttt ccgaaatcta tggaatggat atcccaacat atcggatcgt
      661 gatcggcaaa agctatgcct tattttatcg gatcgaccat gaaaaaaaag agatacttgt
      721 aggacgtatt ttccaatcta aacaaatgaa actaggcttt taacaataat taggaaaaag
      781 tcgctcatcc tctacaggtg ggtgattaat gccgctcgat atggttgtta accgtcggtt
      841 actcgaagat tgatatataa gacttagtac ctttttattt tgctccatgt tatggccgaa
      901 ggtctaaaga tacaatcatt agtctagaga aaaattaaga accgtaggaa ctacggggat
      961 cgcttggtga ataagagaca ctgctattag tgaaaaaata agatatcaag tacgctctat
     1021 tcccaaaaat ttcgtgactt tactcatgag aggttcaagt agtatatttt taatcaaaat
     1081 tgacgtaact tttaataaat actacctaaa taaggtagta tttatttttg tgttttaaaa
     1141 gaggaagtcc aatatatcta tgggaaactt cttaaatatt atgttggtac atgaaaatat
     1201 acatccctgc tagactattt acaacatttt actttgtacg tattcttgtt ttaaaaggaa
     1261 tgggataaaa tataggtaca ataactattt gatgctaaat ataattaatg gaggagagat
     1321 agtgaacata cttaatgaaa aaagatatgt atggtttgct ggtaaaaaat atattactac
     1381 tttcaaaaga ttatccgagt taatgcagca gactgttaaa agtgctatgc ctgaaggata
     1441 caagtttaat tttgttcaat cttcagtatc tactgaaagt atctattttt caattctttc
     1501 tgagagtagg ctttttcatt ttagaataag ttctcatgta aagaaaactg atgttgatat
     1561 atatacgttc cgtacaaata attataaaaa tttaaatgat ttgagtagaa gtatcagtga
     1621 atatctcaag gggaatagct atctcaagat tcgattttca catatattaa ttttactacc
     1681 atatttgaat gagaatttca ccctaattca agtagataag tctttcattg cctcaggtaa
     1741 tcaaggaaat atgaatatta caagtaacaa aacgtcacgt gtgctattgg cgttgatggg
     1801 ttacggaatt ctttatagag atgaccaaaa tggccagatt ctaataaatc gggctgggcg
     1861 ttcattatta atgaaatata gaaaatttat accggaagat tttcaaaact tacagttaga
     1921 aaacatgcgt ttagaagatt tatttagatt agcagaagat gataagtata gatttgaagt
     1981 tttgaaaatt caaaagaatg aactattgaa taagttatat cctgagaatg cgataaaagc
     2041 acattttggt gatgctaatc atatgtatag ttggttcatt cctaaaagat ttagagggaa
     2101 aatcaatgct ggagatcaag tgaaagtact caatcgaaat agtacagatg tcgtaatgat
     2161 aacagatatc tatgtagaag atgaagatat aatcaaatat atgaagcctg tgataaaact
     2221 tgttaataaa aataaaggaa cccgtggtgc tagttaattt tttcctagag
//
LOCUS       DAFLVO010000174         2262 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.180, whole genome shotgun sequence.
ACCESSION   DAFLVO010000174 DAFLVO010000000
VERSION     DAFLVO010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2262
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.180"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(151..2148)
                     /locus_tag="L1U99_002983"
     CDS             complement(151..2148)
                     /locus_tag="L1U99_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBN1213475.1"
                     /translation="MIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKA
                     LVTNKANQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHL
                     KEATKRLSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVY
                     IKNSGVTDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADE
                     AEKYLAKGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGS
                     NLMLSMNAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHE
                     QGSKEITENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKS
                     SVFNRSGQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRD
                     SFKEFGLGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYT
                     PIQLAQYASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMA
                     ILREGFHQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGP
                     TDNPEIAISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          576 a          505 c          411 g          770 t
ORIGIN      
        1 aatttttgtc acaacctttt ttgccgagta aacggtgttc aaaagccagt ttctcggtat
       61 gaagtcaaat ttaagcaaaa atgtgagaag ctattttcac aaaatttttc ttcatactcg
      121 aaactaagcg gctttttcac gacctctttt ttattttgcc atgaacatat cataatacgc
      181 gtccattatt tctttagcaa tcgtcaagtt tatgtggtct tgttcgtcta ataagttcgg
      241 caagacaaca ctgatggcaa tttccggatt gtctgttggt ccgtatgcca cgatattact
      301 attgactgtc gcaatatctg gatgaccttc cgcaaccgtt tctgcagtcc ctgtttttgc
      361 ggaaaggtcc attttcgcac tggctaatgg tttggctgtt gtgtaaggat cggtaccatg
      421 gacaacttgg tggaatcctt cacggaggat cgccatattt tctgcagaaa tattgaccgt
      481 attttctact gttgtgccaa tttctttctt cacttcaccc aagtttccat tttcgtcatt
      541 gccatagatc gctttgacta ggtgcggctg tactcgtttc ccgccattag cgactgttga
      601 agcatattga gctaattgga ttggtgtata tgtgtcaaac tgtccaaatg ccaaatcggt
      661 aaagttacct ggagcatacc attctttgcc attatccgca ttgaacttct tcatataatc
      721 aacagaacgt gagatcccag gagattcatt cggcaaatcg atcccagtcg ttgtaccaag
      781 accaaactct ttgaaagagt ctctcaattg ctgataagct ttagcttctt catctaaact
      841 aggtagtccc attccaggtg tatagtctag tcctaacatc tttaacgcca ctttgatcat
      901 atacgtatta gaagacaatt ccgatgcttt gactgcatca agagcaactt gtccgcttcg
      961 attaaagaca gagctttttt ctgaagcacc ttgcagacga atcggctcat caatcaaaac
     1021 ttgatttccg ctgatcgcgt tacttgccca gcctgctgtc aaagtaccag ccttgactac
     1081 agaccctgga tcaaaggcgc tagtaatcgt gcctaaagca ttctcggtga tttctttgga
     1141 accttgttca tgactgaaac cagtcattgc tagcacttct cctgtctgag gattcatagc
     1201 cactgcataa gcaccaggcg aatactgtgc tttgccgttg ttgatcaatg tttgataatt
     1261 ccttttcaaa atttcttcta cttttgattg gaattctgca ttcatagata acattaaatt
     1321 agaacctttt tccccagaga agatttcttt ttgattcgaa acatttcctt cattatcaag
     1381 ggaaacttca tattgggttt tggttccttg caggacatct tcatattgtt tttccaaata
     1441 actttgtcct acacggtcat tccgagaata accttttgct aggtatttct ctgcttcatc
     1501 tgctggaagt ccttgctttt cagtcgtcac actgccaaga atacttttca gtgaacttgc
     1561 tgcattatat tctcgtgtcc agtctgtgcc agtcgaaact cctggaagtt cagaagcgcg
     1621 ttctgccaca acagctaact cttgatcagt aacaccagag tttttgatat agacagtgtt
     1681 taattcatat gcactattca tccgtttaaa gatggtagca atttttaatt gctcctcgtt
     1741 taaattaatc tcatcagctg tgactttatt gaccatcgca ctatattgtt cgctgttccc
     1801 taattgcttt tcttttgccg aaagtctttt tgtggcttct ttcaaatgtt tgggatcagc
     1861 cagccaaaaa tcttttttat ctctatctgt cagattttca tctaccggaa catcgatcag
     1921 cgagttcagc ttcgttgcga tttcaagcaa atctttagcc gtaacttgtg ttcctctcgt
     1981 atatgtgatg gcctgattcg ctttattcgt aactaaagct tttcctgtgg agtcgtagat
     2041 cattccgcga ggagtacttt cttggaccgt aatcgtagaa gtagacttca ctcgcgcctc
     2101 catctcttcg ccgttcacga tctgcaaata acccaatcta gcaatcaacg caacaaataa
     2161 cgtaaatata atgaaaaaaa gaaaatttaa gcgaaaagga acatgggacc ggcgaaacgt
     2221 tttgttctta ggttcttgtg caccttttct tattttttct aa
//
LOCUS       DAFLVO010000175         2202 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.181, whole genome shotgun sequence.
ACCESSION   DAFLVO010000175 DAFLVO010000000
VERSION     DAFLVO010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2202
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.181"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            24..926
                     /locus_tag="L1U99_002984"
     CDS             24..926
                     /locus_tag="L1U99_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1213476.1"
                     /translation="MNQSVAKTAHCLNRSRQTIHKVYLFFKQGKSALEYYQQYKKNKS
                     NCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPISCSARTIYRMFKKGLFDSSD
                     LPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHLEGDTIVGLKHKSAVIT
                     LVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFKSITFDCGKEFSNWKQISNV
                     NDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSVDEFFIQSAASKRNNIPRK
                     SLDYRTPLEVFLSYVSIDDLSNLI"
     gene            complement(1179..1328)
                     /locus_tag="L1U99_002985"
     CDS             complement(1179..1328)
                     /locus_tag="L1U99_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213477.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            1790..2002
                     /locus_tag="L1U99_002986"
     CDS             1790..2002
                     /locus_tag="L1U99_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213478.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
BASE COUNT          791 a          345 c          383 g          683 t
ORIGIN      
        1 taataataga gtcttatttc aaaatgaatc aatctgttgc taaaactgcc cattgcttga
       61 atcgttcaag acaaacgatc cataaagtat atctgttctt caagcaagga aaatcagcct
      121 tagaatatta tcaacagtat aagaaaaaca aatcaaactg tggtagacgt ccgcttgttt
      181 tacccgagga acaatcagaa tatattcaaa gaaaggttgt tcaaggatgg acacccgatg
      241 tgattgttgg tcgtgcagcg tttcctatta gttgttctgc tcgtaccatt tatcgtatgt
      301 tcaaaaaggg gctatttgat tcttctgact taccgatgaa aggcaagcgt aaaccgaatg
      361 gacatcaaga aagacgtgga aaacaaactt tccgccgctc tattcatgaa cgtgaaaagg
      421 attatagcca attctcaaat gagtttggtc accttgaagg tgacactatc gtaggtctga
      481 aacataaaag tgctgtaatt accttagttg aacgattatc aaaagttatc atcacattga
      541 aaccgtgtgg tagacaagcg attgatattg aaaaaaaatt aaatcaatgg tttgaatctg
      601 taccgaaaaa cctattcaaa tccatcactt ttgattgtgg aaaggaattt tcaaattgga
      661 aacagatcag taatgtcaat gatattgcca tttatttcgc tgatccagga acgccgtctc
      721 aaagaggcct aaacgagaat tctaacggat tgttacgtag agatggttta ttgaaatcta
      781 tggatttcaa ttcagtagat gaatttttta ttcaatctgc cgcatctaaa cgaaataata
      841 ttcctagaaa atcactggat tatcgaacac ctttggaagt atttttgagt tacgtaagta
      901 ttgatgatct gtctaactta atttgacaat taagattata ttaaatatta tacagataat
      961 aacggaatat tatcatcgaa acagctaaca aaattgtcat aaaaaacgag atggttgata
     1021 ttagaacttg tgtttttgtt taggtctaga gataaagaga gacaatttcc aaatatatgt
     1081 aatgaataca aaaagacgtt tgtcgcggat taccgttaca aacgtctttt attgattttc
     1141 cgagatctca tcagtcgcca tttggaatgg ttcactcctt atctagattc gtttaatgct
     1201 cggactgctt gttcgattgt aataccaaac gcaacgttat tttcgttttg tgcatcaatc
     1261 gccataaaac ggttagaagt tgtatcaaaa gctacgcggt attgcatatt tgtttttgta
     1321 aacgtcataa aattcatctc ctttgtaatg taatttagtt cttgaaagtt tcctttaaac
     1381 tttcgaactt ataccaagtt tagcatcgta cgttttttga tgcaattaaa aagcatttat
     1441 cattttcctt atttattttt tcttaaatgg tttagctatt ttcttttaat ccgataagta
     1501 gcccaatcat caaggttaca aatactattg cttgaatata aatcatatgc tcacctcttt
     1561 ataaataact tagcaatata aagaaaaaaa cgcacgaaca acataggaat ataaacaaac
     1621 gtttttgtca caacgtctaa gatcgtgtta aaaaatagtt atctaaaaag cagaaagata
     1681 ctcaaaataa aaaataaaaa aatggataaa aacgttttca aatacaaggt aatttgttat
     1741 tataaaataa agaaaaaaca aaataaaaat aaagaaaaga gggaatgaaa tggtaaaagc
     1801 agaagtagga agatcttata tatgcaaacc gatcggagta tctcatgaac taatcggctg
     1861 tattgaacgt acatatatca acacggctgt cgtgtatgtt gaaagttatg accaacgaga
     1921 ctatcaactt atcaatgaaa gcaagtatcg catgctcgta aaattctgtg atattagcgc
     1981 acctgctgaa ttggtttctt aaacagtatt tttgagaatt cgcaagaact cccttataat
     2041 ataaataaag acagaaggga gcgagaagat atgccaaaaa gaaaaagttc agggaaaatg
     2101 ggaattattc ttgcagtgat ctctgcaatt cctgctattt tagctattgt tcgtgcgatg
     2161 aaggaatcaa gagaaagtta agcacacatt atgagcgtca aa
//
LOCUS       DAFLVO010000176         2175 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.182, whole genome shotgun sequence.
ACCESSION   DAFLVO010000176 DAFLVO010000000
VERSION     DAFLVO010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2175
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.182"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            297..1622
                     /locus_tag="L1U99_002987"
     CDS             297..1622
                     /locus_tag="L1U99_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBN1213479.1"
                     /translation="MFDYSREPVNDYFLIDMKSFYASVECIERNLDPMTTPLIVMSRS
                     DNTGSGLTLASSPTAKKKYHITNVSRATDLPYPLPKELHIVPPRMNLYIKKNMEVNQI
                     FRKYVADEDLLIYSIDESILKVTKSLNLFTSSGTRSERRRELAKIIKDEIQKETGLIA
                     TVGIGDNPLLAKLALDNEAKSSKEFIAEWTYETVPEKIWKINEMTDFWGIGSRMKKRL
                     NHMGIMSIEDLANWNPYTIKSQLGVIGLQLYFHTNGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPKDYTRREEVELVVKEMAEQVAIRIRQHNCKTGCVRLAIGTSILEEKSGFSHQMKI
                     PITDNTKELQNYCLFLFNKFYEGQEVRHIGVTYSRLVYTDSLQLDLFSDPRKKIAEEN
                     LDRIIDKIRQKYGFTAIIHASSMLEGARSITRSTLIGGHAGGLGGLHND"
     gene            1615..1962
                     /locus_tag="L1U99_002988"
     CDS             1615..1962
                     /locus_tag="L1U99_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213480.1"
                     /translation="MIEYNDRGRLKWSGFYLSDHTERINADNVQRANHNLAKEQMTTE
                     EIAKILRTAVIKNRPVCIQKEERNAEGYYPDDVVGKIIGYDELGVFVEEEKVHYDEIR
                     NVSFSELLKWSQI"
BASE COUNT          824 a          294 c          418 g          639 t
ORIGIN      
        1 cggaaggacg aatgttgttg aggttttaga accatataaa acagcatagt tctcaaattg
       61 tttaaaatga ttgtcaagtt aaaaaaatct gggatcatat aaaatagtat agttctcaaa
      121 tatgattaga aaccctatta aagagcaata ttaagccaac ttacttaaat cgtttaatta
      181 agaacaataa tctcttttag tcagactttt agtctgactt ttttgtattt ccaaaattta
      241 ttctttacaa aaacgaacat acgtttgtat aattgcttgt gaatggggga ataaaaatgt
      301 ttgattacag tagagaaccg gtgaatgact attttttaat cgacatgaag tctttctatg
      361 ctagcgtgga atgtattgaa cgaaatttag acccaatgac tacaccgtta attgtcatga
      421 gtagatcgga caacactggt tcaggtctga ctctagcttc ttcacctact gcaaagaaaa
      481 aatatcatat tactaatgtt agtagagcta ctgatttacc ttatccatta ccaaaagaac
      541 ttcatattgt tccaccacga atgaacttat atataaaaaa aaatatggaa gttaatcaga
      601 tttttagaaa gtatgtcgca gatgaagatt tattgattta ttcgattgat gaatcaattt
      661 taaaagtgac aaaatcctta aatttattta ctagttcagg aacaagaagc gagagaagaa
      721 gagaattagc taaaataatc aaagatgaga ttcagaaaga aacaggtcta atagcaacag
      781 tcggaatagg agataaccca ttattagcta aacttgcact ggacaatgaa gcgaagagta
      841 gtaaagaatt tatagctgag tggacttatg agactgtacc tgaaaaaata tggaaaataa
      901 acgagatgac tgacttttgg ggcattggat cacgcatgaa aaaaagattg aatcatatgg
      961 gaattatgag tatagaagat ttagcaaatt ggaatcccta cacaattaaa agtcagttag
     1021 gtgtaatcgg actccagtta tatttccata ccaatggaat tgatcgtacg gatattgcta
     1081 ttccaccaga accaaccaaa gaaaagtctt atgggaattc acaagttcta ccaaaagatt
     1141 atacgaggag agaagaagta gaactagtag tcaaggagat ggcagagcaa gtagccattc
     1201 gaattagaca acacaattgc aaaactggtt gtgtacgctt agcaattggt acgtcaattt
     1261 tggaagaaaa atcaggtttc tcgcaccaga tgaaaatacc aattacagat aatacgaaag
     1321 aattacaaaa ttattgtctt tttttattca ataagtttta tgaggggcag gaagtacgac
     1381 atataggagt aacttatagc agattagtat acacagattc cctacaatta gatttattta
     1441 gtgatccaag aaaaaagatt gctgaagaaa atttggatag gattattgat aagattagac
     1501 aaaaatatgg atttacagct attatacatg cttcatctat gttagaaggt gcaagaagta
     1561 ttacgagaag cactttaata ggaggacacg caggaggatt aggaggtttg cataatgatt
     1621 gaatataacg atagaggacg tttaaaatgg tcgggatttt atttgtctga tcatactgaa
     1681 agaatcaatg cagacaatgt acaacgtgct aatcataatt tggcaaaaga acaaatgacg
     1741 actgaagaga ttgcgaaaat actgagaact gctgtcataa aaaatagacc cgtctgcatt
     1801 caaaaagagg aacgaaacgc tgaaggttac tatccagatg atgtagtagg aaaaattatt
     1861 ggatatgacg agcttggtgt atttgtggaa gaagaaaaag ttcactatga tgaaattagg
     1921 aatgtttctt tctcggaatt attaaaatgg agtcagatat gaacattatt aaaaaatacg
     1981 aattcggtta tattacgtat gaacagctaa tagaggaatt atggggatat ggtcaacaat
     2041 taattaatga agtggggatt gattgctttt gtttctatat tgaatccgga gcaggatacc
     2101 ataagaacag atactatata tttccatatc caccaaaata gtctcttaga tatttttaaa
     2161 ttttctccaa atact
//
LOCUS       DAFLVO010000177         2119 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.183, whole genome shotgun sequence.
ACCESSION   DAFLVO010000177 DAFLVO010000000
VERSION     DAFLVO010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2119
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.183"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..177
                     /locus_tag="L1U99_002989"
     CDS             <1..177
                     /locus_tag="L1U99_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBN1213481.1"
                     /translation="LLNNKISFEENIVKEMPESANDMYEKELKYFFENVVTGKENWND
                     LYHANEVLKIAEEK"
     gene            178..930
                     /locus_tag="L1U99_002990"
     CDS             178..930
                     /locus_tag="L1U99_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HBN1213482.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            935..1882
                     /locus_tag="L1U99_002991"
     CDS             935..1882
                     /locus_tag="L1U99_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBN1213483.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT          742 a          279 c          421 g          677 t
ORIGIN      
        1 ttattaaata ataaaataag ttttgaagaa aacattgtta aagaaatgcc tgaatctgct
       61 aatgatatgt atgagaagga gttgaaatat ttctttgaaa acgtagtaac aggcaaagaa
      121 aactggaatg atttatatca tgcaaacgaa gtattgaaaa tagctgagga gaaataaatg
      181 gaaattttat ttactatttg tggtagagct gggtctaagg ggtttaaaaa taaaaatttg
      241 aaatatttgg caggaaagcc cctagtccat ttcgctttag caatgataga tatctatcaa
      301 caaaaacatc ctgaacataa ttgcacgact tgtttgaata cggacagtaa tgagttagta
      361 gaattgacga ctaagttaaa tccgtctgtg aaaattgtag aacgtaaacc tgaattagct
      421 acagatactg tagggaaaat tgaagtgata cgtgattcat tcttacaact agaaagagaa
      481 gataatatat ttgatttaat tatagattta gatttgactt cacctttacg tgaagtttct
      541 aatcttgaag aattaataga tgaacatcta aaaaatttag ataaagacgt ctacttttca
      601 gttgtttctg caagacgtaa tccctatttt aatatggtaa aaagaattga aaatgaagtt
      661 actatagtta ataaatcaag atacacatct aggcaacaga cacctgaagt ttttgaaatg
      721 aatgcctcaa tgtattcttt taaacctgaa tttctaaaaa aaagtaatta tatttttgat
      781 gggcaatgtg ggataataaa aatgagagat tatctaattt tagatattga tagtgaagaa
      841 gattttaaat ggttagaatt tttgtttcct aaatttttag aagattcttc ggagcttcaa
      901 gatatctata attatttata tcggaggtaa aaggatgagc tgttatctta tcaccggtgg
      961 ggctggcttc attggttcta ccttagccaa tcatttagga gaagaacatg tggtaatcgt
     1021 cgtcgatgac ttatcaatgg gaaaagtaga aaatcttgat atgacgaaaa atatcacttt
     1081 tattgaggga gatgtcgctg agaaatcctt gatggaagag atcatgaaag ctaataaatt
     1141 tgattatatc tttcatttag cagcagttgc tagtgtggca gattcagttg cccgaccagt
     1201 agaaacacat cgtgtgaatt ttgaaagtgt attaatgatt ttagaattga tccgcaagta
     1261 tcaacctgat ttaaaacgga tcgtgtttag ttcttcagcg gctgtttatg gggatgaacc
     1321 gactttacca aaaaaagaag agtccgtgat tcgcccattg acgccttatg cggttgataa
     1381 attcgctgca gaacaatatg tgctagatta ttgtcattta tatgatgtac ccggtagcgc
     1441 agttcgtttt ttcaatgtct atggtccaaa tcaaaatccg aattctccat acagtggtgt
     1501 gatttctatt ctcgtagatc gctataagaa acaaatcgta ggagaagcaa cttcatttac
     1561 attatttggt gatggaagcc agtctagaga ctttgtttat atagatgatg taatccaagc
     1621 attactttta gttgcgaatg aggaagctgc actggggaaa caattcaatg ttggaacggg
     1681 taaagcaacc acacttttgg aattgattca tgcaatcaat gaaattctcg gtgtagaatt
     1741 gacacttgaa tacaaagaag agcgttcggg tgatatccat gactctctag cagatattac
     1801 taagatccag tcaattggct atcaaccgaa atatggtatt ttaagtggaa tgactaatta
     1861 tttgaaaact gaaatcaatt aaaacatact aagataagat tagagggtaa attcaggctc
     1921 tttgtcaata aggactgatg agttttgtaa aatcaaatct gggatagaag ggctctttgt
     1981 caaatgatgt tggtaaagag aaatcttaga ataatttgga cagaacagaa agaagaaaac
     2041 ctctttctgt tctgtttatt tggttaaaaa tgttttgcca tgacgaatca taattcgtag
     2101 tttgaaattg taaaagttg
//
LOCUS       DAFLVO010000178         2070 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.184, whole genome shotgun sequence.
ACCESSION   DAFLVO010000178 DAFLVO010000000
VERSION     DAFLVO010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.184"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(594..959)
                     /locus_tag="L1U99_002992"
     CDS             complement(594..959)
                     /locus_tag="L1U99_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213484.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1035..1280)
                     /locus_tag="L1U99_002993"
     CDS             complement(1035..1280)
                     /locus_tag="L1U99_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1213485.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1350..1604)
                     /locus_tag="L1U99_002994"
     CDS             complement(1350..1604)
                     /locus_tag="L1U99_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213486.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(1768..1980)
                     /locus_tag="L1U99_002995"
     CDS             complement(1768..1980)
                     /locus_tag="L1U99_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213487.1"
                     /translation="MIFQGVITLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIIL
                     SFLVNAIVLFLYVLNYLDINPLIFSR"
BASE COUNT          763 a          353 c          369 g          585 t
ORIGIN      
        1 taagcttttt taaagaatat ttagaaatta ttaattttcg tctgaaaaca aaaaaagaaa
       61 gcgttattat tttagtctat tttcaggggg ggaaccttat gataaaaaaa ctatttttac
      121 tatcaatatt aacgctagca atggcaggtt gttctgactc tggcttagca actgaactga
      181 tcacaaaatc aactgaagcc acgacagagg agttaaaatg tggaaacgat cacagtgact
      241 acagaggctt aaatcgacga tgcatgggaa tattaggcag aagcaattgt aagcatcgat
      301 gtagtaatcg aagaaggtgt agaagaagca acagaaaaat caaaagaaag atcaaaagaa
      361 gcaatctgtg ctgtgcatcg tatacagacg tcgaagatgc ggtactttta aaccacgtca
      421 ggagatgttc atttatgtct agggaagttg gcgatgaacc aaaactagag tacgctttta
      481 gttttgcacg tgaggatgaa gataacccta aaacttacga cattttagct tgatctaaga
      541 tggttaaagc tttttaatga agtaagagga gatagaaggc ttttctagtt atattaggta
      601 agataaattc ctttttgctc caaatttgct aaacattctg ctagataaac ttcatcgtgt
      661 tccggataaa tcggcacgtt gcgctctaca gtaggtaaat caaaaaatgc ttcgcatgat
      721 ttgccacgat acataggatt tttccactct ggtgctgggc tgtaaccacg tttttccatt
      781 tcatccatga caagctgatg atattggaat aatctataag gagaatagtg aaaaacataa
      841 tccacagtag catgtttctt tccccagcca tttcctctta atgcacagca ttcccgatgt
      901 tgtcctaaaa gctgttgacg aggaagcttt gaaatcaatt tttcatgcca taatcgcata
      961 gaaatgtctc ctttatatat agattgttaa ccttagacgt taaatgaaaa aaccagcacc
     1021 aaggctggaa aaaatcactt cagtttgctt gctgtttctg agcgaccaat taggtaatca
     1081 acggaaatat cgtaaaagtc agcgatatag attaattcaa tgatgcttgg aatttcttct
     1141 ccttcttcgt acttacgata tttgaataaa ggaatactta acgcgctaga aacagctact
     1201 tgagataaag atcggccagt tcttaagaaa ttcagacgac aacgtaaagt atccagtaaa
     1261 atagcttctt cgatactcat ttaatcacct ttcattatag tagaatagtt ataatgacta
     1321 tagaaagcta cacatgcaat caatagtact caatgttttt tatttaaacg tatcaaataa
     1381 agaatgacga tcaataaaga caaaaccagt cctgataatt cttctataaa aacactatcg
     1441 ggttcaaagt agttgtaatt aaaaactttc cacataaagt agatagccgg aagagtcaaa
     1501 atagctaaat aaaaccgttc tttgttccaa ttcataagat aaacaatact tgcgaccagt
     1561 gcgaccgcag gcacccaaaa caaaactctc accaacgtaa tcatgtaacg gactcctcaa
     1621 cgattcatat aataaaagat aacatgttat tgcatacatc acaaatgaaa tgctaggaaa
     1681 ataaaagaag aatagatcaa tgaaaaatga aaaagcagaa cagttttctg ctgataagca
     1741 ggaactgttc cgctgaatgt gtcttatcta tcgagaaaaa atcaatggat tgatatctaa
     1801 gtaattcaat acatataaaa agaggacgat cgcattcact aaaaaggaaa gaatgatgat
     1861 cccatagcga atggaaacat atttaacaaa tacttttgtt tgaatacggg catatctttt
     1921 tcctttatag ctgagcatca tgacaagaag caaaagggta atcacacctt gaaaaatcat
     1981 tccaataaac agaattcctg aggtttgata atttaattgg agaaaataag ctgctgccgc
     2041 aactaaatcg aataaaatcg caataaatgg
//
LOCUS       DAFLVO010000179         2053 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.185, whole genome shotgun sequence.
ACCESSION   DAFLVO010000179 DAFLVO010000000
VERSION     DAFLVO010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2053
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.185"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..122)
                     /locus_tag="L1U99_002996"
     CDS             complement(<1..122)
                     /locus_tag="L1U99_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1213488.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGVNEGSS"
     gene            complement(133..330)
                     /locus_tag="L1U99_002997"
     CDS             complement(133..330)
                     /locus_tag="L1U99_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBN1213489.1"
                     /translation="MILPDKYYQVIKWTVLTVLPALSVLVATLGKAYGWNGTDMAVLT
                     INAAATFLGVITGVSAYNLKK"
     gene            complement(353..646)
                     /locus_tag="L1U99_002998"
     CDS             complement(353..646)
                     /locus_tag="L1U99_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213490.1"
                     /translation="MINLGEWGTIAGSITAIVSLILLVIRPVTASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERSR"
     gene            complement(683..820)
                     /locus_tag="L1U99_002999"
     CDS             complement(683..820)
                     /locus_tag="L1U99_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBN1213491.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEADKIISKEESA
                     S"
     gene            complement(822..1268)
                     /locus_tag="L1U99_003000"
     CDS             complement(822..1268)
                     /locus_tag="L1U99_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213492.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            complement(1265..1414)
                     /locus_tag="L1U99_003001"
     CDS             complement(1265..1414)
                     /locus_tag="L1U99_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213493.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPILNWKPKFNY
                     WEGNK"
     gene            complement(1431..>2053)
                     /locus_tag="L1U99_003002"
     CDS             complement(1431..>2053)
                     /locus_tag="L1U99_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213494.1"
                     /translation="TRTPNISEYKYRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKI
                     SEITGKANNYTDGKVSEINSQLTASINEVDTTAKDAQTKANANATAIDELDNKIDERI
                     NDTATTTLTVTNGNTGSAKLYREGKTVSIYFVALNGKSSGGNDSTILTIPEGYRPPIS
                     FEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSDYTFAITYTI"
BASE COUNT          558 a          424 c          323 g          748 t
ORIGIN      
        1 gaactacctt cgtttacacc taaattaaat tcattgttaa tcgtataggc aaacccatta
       61 atcggcaata aaaaaagagc cgttaatagg ctcatcgcag taatagtaat tttctttttc
      121 atttgtttcc tcctattttt tcaaattata agccgacaca ccagtgataa cacctaaaaa
      181 tgttgctgct gcattgatag tcagaactgc catatctgtt ccattccatc catatgcttt
      241 gcctaatgtg gctactaata cagataaagc tggcaatact gttaaaactg tccatttaat
      301 gacttgataa tacttatcgg gtaaaatcat ttcttcttaa ctcctttctt ttttaccgag
      361 acctttctct aaataaagtt ttaatttgtt gtgtgtgttc taccaatttt tctgcatgtg
      421 tatctaatct ttcatcgtgt ttctttagtt cttcatgaat catcaatcga tctgatttgc
      481 tcgattctaa atctttagtc agcaaatcta aattgtgact tacttttgaa agagtttcag
      541 taatcttcga gaaagatgca gtgactggtc ttattactaa taaaatcaaa gaaacaatcg
      601 cagtaattga tcctgcgatt gttccccatt cccctaaatt gatcatgtga caactccttt
      661 accttaaata aaaacgcatc acttaagatg cgctttcttc tttgctaatg attttatctg
      721 cttcttcgtc tgtaatgcat agtggaacga atagtcgaac ttgatcgtca gtaaaacagc
      781 cccaatcata catcattttc acatcgctaa aactaaacat actactcacc tccctttgaa
      841 gctggattta gttgctcttt aatttctgaa atgtctttgc tattttgtaa cgaagcaagc
      901 atcatttttg aattgatttg tgctaaacta tccgcttttt ctttcaatgc agtattttcc
      961 tgtttaattg ctacatcgct tagcatgagt ttggcattga tctgttttaa atcgccgttc
     1021 tcattttcta acgactcata cattgctttg agattgttta aatcgttgtg atctagtgcg
     1081 ttcgctaaaa taatccattg attcaattta ggatcaaaca tttgatcagc gattgttaac
     1141 ggttcgccat cagcacgaat tccttcaagc ggtggctgat ctgtgtaagg aacggataca
     1201 agcatgtcgt ccaatacttt tcctgcgtac tctccgccag tacgtccata tttccaaatg
     1261 tttttcattt atttccctcc cagtaattga atttcggttt ccaatttaga atcggtggtt
     1321 cgacttctgt gcattcttcc ggtaaatgtt cttcatcatt cacaatgatt tgctcgaatc
     1381 cgtaaggttc aattggtcta tatgctgcct tcatatcgat tcacgctttt ctaaatcgtg
     1441 taagtaattg caaaggtata atccgatcca taacttgagt ttcttcgcca tttaatggct
     1501 ccatctgcac caatagataa ctgagcactg ttcaaagtag aacggtctat cgagccaacc
     1561 agttgctcaa aactaattgg tggccgatag ccttctggaa ttgttagtat cgttgaatca
     1621 tttccaccac tgctttttcc gtttaaagcc acaaaatata tagaaactgt ttttccttca
     1681 cgataaagct ttgctgatcc ggtattcccg tttgtaactg ttaatgtggt agtagctgta
     1741 tcattaatgc gttcatcgat cttattgtct aattcatcta tagcagtcgc attagcattc
     1801 gcttttgttt gagcatcctt agctgtggtg tctacttcat taattgaagc agtcaactgc
     1861 gaattaatct ccgatacttt cccatcggta taattgtttg ctttaccagt aatttcagaa
     1921 attttaatat ctgtggccaa attatcttcg acatattctg gtgctagatc ccaaacataa
     1981 tcttttggat tgtttgaatc acgcatacca gtaccacgat atttatactc actaatattc
     2041 ggggttcgag tat
//
LOCUS       DAFLVO010000180         1998 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.186, whole genome shotgun sequence.
ACCESSION   DAFLVO010000180 DAFLVO010000000
VERSION     DAFLVO010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1998
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.186"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..278)
                     /locus_tag="L1U99_003003"
     CDS             complement(<1..278)
                     /locus_tag="L1U99_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213495.1"
                     /translation="MKEISANEAHIPQKNQVGIYKVLHGEGIYKIQLLTGYNNGANGK
                     WLKATSIRELRSEVEKIRLGLTSEEIAKLKGNNSFVIEKEKEKHLLYR"
     gene            complement(409..1131)
                     /locus_tag="L1U99_003004"
     CDS             complement(409..1131)
                     /locus_tag="L1U99_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213496.1"
                     /translation="MKSTKLKVVLLSTAALITLTACGTTNSANNNKDTKSSSTMVTKN
                     STTSASTTMSSMTENNAEKYQKYEDINKGQKPDEVYNNFINTVKNDENYGNDPLQNKN
                     LTIVLYKPDCPDCQKAESKIMQEIKEGFSYAPTLMHDITINKPAYEYYAVAVDITDGV
                     PEWVQNIPGLADENNQYHTPTVAVVTPKKVNGTLYWDVMGMTTNTTDEMIESTTKYYM
                     DLGAYKLYQQSEPVMDDQSKVK"
     gene            complement(1137..1382)
                     /locus_tag="L1U99_003005"
     CDS             complement(1137..1382)
                     /locus_tag="L1U99_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213497.1"
                     /translation="MKKIINQPTNHLIIEGVIFVTMYFTVGNGISNTIIQKNPQYLLF
                     SLYAWIVQMVWVSILMLLFYWIVRVILLLLNKRKKDR"
     gene            complement(1393..1977)
                     /locus_tag="L1U99_003006"
     CDS             complement(1393..1977)
                     /locus_tag="L1U99_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213498.1"
                     /translation="MDLKQSFYIWLYPDNPMSIMADIFVVSILLYLFYLIFFHNLIGY
                     MILDWKGMFDIERKPFANNQTYTVFESGDWEENEVDVIHEIGLALSGIQDADVLVSMT
                     TDTGYNAYEVFYLMYFIWRDGQEIINGRAEKTINSNTEISFCMGEGEMIVYKDGSANI
                     KTAFGDIETSIKELREYVQNPYNFQYLAGRINLV"
BASE COUNT          596 a          368 c          264 g          770 t
ORIGIN      
        1 tcacgataaa gtagatgttt ttccttttct ttttcaatta caaaagaatt atttcccttc
       61 agtttagcta tttcttcact tgtgagacca agcctaattt tttctacttc acttctaagt
      121 tcacgaatac ttgttgcctt taaccacttc ccatttgcac cattattgta accggtaagt
      181 aactgtattt tataaattcc ttcaccatga agcaccttat atataccaac ctgattcttt
      241 tgcggaatat gagcttcatt tgcactgatt tctttcatta cgcattctcc tttataatct
      301 agttaattag cttgtgtgtt tcgagtagtt gagtaagaac gtttgtttca gaaatcattt
      361 atttgttatc acttaatttt aaaaaaatag ggcttacgcc ctaaagatct atttaacttt
      421 ggattgatcg tccataacag gctctgattg ttgatataat ttatatgctc ccaaatccat
      481 ataatattta gttgtacttt caatcatttc atcagttgta tttgttgtca ttcccattac
      541 atcccagtat agtgtgccgt taactttctt tggtgttact actgcaactg ttggcgtatg
      601 atattgattg ttctcatcag ccagaccagg aatgttttgt acccactcag gtacaccatc
      661 agtaatatct acagcaactg cgtaatactc gtaagctggt ttatttatgg taatatcatg
      721 cattaatgtt ggagcataac taaatccttc ttttatttct tgcatgattt ttgattctgc
      781 tttttgacaa tctggacaat caggtttgta aagaacgata gtcagatttt tattttgcaa
      841 tggatcattc ccataatttt catcattttt tactgtatta ataaagttgt tataaacttc
      901 atccggcttt tgacctttat taatgtcttc gtatttttga tacttttcag cattattttc
      961 agtcattgaa gacattgttg ttgatgccga tgtagtgctg tttttagtaa ccatcgtact
     1021 actagacttt gtgtctttgt tattattagc actattagtt gtaccacatg ctgtaagggt
     1081 tattaatgct gctgtcgata acaatacaac cttcaattta gttgatttca ttttattcac
     1141 ctatcctttt ttcttttgtt taacaataaa agaataaccc gtactatcca ataaaacaac
     1201 agcatcaata tggaaaccca aaccatttgt acaatccaag cataaagact aaataatagg
     1261 tattgtggat ttttttgaat gattgtattt gagatgccat ttcctacagt aaaatacatt
     1321 gttacgaaaa taacaccttc aattatcaag tgatttgttg gttgatttat aatttttttc
     1381 atatttttac tcctaaacta aatttattct tcctgctaaa tattgaaaat tatatgggtt
     1441 ctgcacatat tccctaagtt ccttaatact tgtttcaata tcaccaaagg ctgttttaat
     1501 gtttgctgac ccatctttat atacaatcat ttccccttca cccatacaaa aagaaatttc
     1561 agtattagaa ttgattgttt tttcagcacg accattgata atttcttgac catcacgcca
     1621 tataaaatac ataagataaa atacctcata agcgttgtat ccagtatccg ttgtcattga
     1681 taccaaaaca tcagcatctt gtattcctga taaagctaat ccaatttcat ggatcacatc
     1741 aacttcattt tcttcccaat ctccactttc gaagacggta taggtttgat tgttagcaaa
     1801 tggttttctt tctatatcga acattccttt ccaatcaaga atcatgtacc cgattaaatt
     1861 gtgaaagaaa attagataaa ataaatacaa taagatgcta actacaaaaa tatcagccat
     1921 tattgacata ggattatcag gatataacca gatgtaaaac gattgtttca aatccatttt
     1981 ttcatcatct cactctac
//
LOCUS       DAFLVO010000181         1911 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.187, whole genome shotgun sequence.
ACCESSION   DAFLVO010000181 DAFLVO010000000
VERSION     DAFLVO010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1911
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.187"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..969
                     /locus_tag="L1U99_003007"
     CDS             <1..969
                     /locus_tag="L1U99_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1213499.1"
                     /translation="PINTFAYTINDEYNLAPNQGDSRLAIPNKIILHETGIDAPARNV
                     AANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAGNANPYAPVQIELQRTYDKA
                     LFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIISHLWVTNYVWGNHTDPYGYL
                     SQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNHAHIDQFGE
                     IENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGNVGYH
                     VSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
     gene            1159..1232
                     /locus_tag="L1U99_003008"
     tRNA            1159..1232
                     /locus_tag="L1U99_003008"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1193..1195,aa:Ile,seq:cat)
BASE COUNT          639 a          327 c          362 g          583 t
ORIGIN      
        1 cccattaata cgtttgctta tactattaat gacgagtata atttagcgcc gaatcaagga
       61 gactccagat tagcaattcc taacaaaatt attttgcacg aaactggaat agatgcacca
      121 gcaagaaacg tagccgccaa catgaaaaat aattataacg gaagcaattc ttatactaca
      181 gatgttattg gtgacggtgg gattgtttac cgtgtgggtg agcaaggata tgtttcgtgg
      241 ggagctggta acgctaatcc ttatgcgcct gtacagattg aattacagcg cacatatgat
      301 aaagcattgt ttgaaaaaaa ctatcgagct tatattgaat atacaagaga tagtgcaaaa
      361 aaatatggaa ttccattgac tcttgatcaa ggaacttctt tatttacaaa aggaatcatt
      421 tctcatttgt gggtgacaaa ttatgtttgg gggaaccaca cagatccata tggttactta
      481 tcgcaaatgg gagttagcaa agaaaagctt gcttatgatt tagctcatgg atttaccgat
      541 gaaaatccaa caacttctga aaacaagcct gtcattgatc caacacgagc tggtgcagct
      601 aatcctacgc tgacagatgg aacaaatcac gcccacattg atcagtttgg ggaaatcgaa
      661 aacgcaaact tgcatgtggc tggatggcac attgctaact ataaatacga gtatattttc
      721 attatggact acaatactgg gaaagaatta gctcgagtaa gagctgatgg aatttataga
      781 ccagatgtaa accaagctta taatacttct ggaaatgttg gttatcatgt atctttcaat
      841 atgcgtaatt ttcctagtaa gaaagtctat gtaatgatgc gggcaacgaa tgatccagag
      901 ggaaacacta aaggcggtgc gcaagatttc catgacaaac gttggtattt aaatattcct
      961 aaacgataaa aatagctcct cgttgaggag cagtacataa ctatattgac aactataaaa
     1021 attattcgat aaaatagtga tgttatcgca tatcttcact atcacccata aatagtcaca
     1081 ctccaagcta tgcgataaca ggtttgttgc cacacattct actggttgat tgtttatggc
     1141 tttatgtggc aacaaccagt acccttagct cagttggtca gagcagacgg ctcataaccg
     1201 tccggtcgta ggttcgagtc ctacagggta cattaacgta gccatttgaa tcgttctgtg
     1261 ttagaatttt tttgaagagt attatacaag ctaaagcttt tcttcattgc cactcaaatg
     1321 agtggctttt ttatgtatcc ttttatggat taatgaaagg atgtttcaca tagttatact
     1381 tctgtatatt tgaaaagttt tactttgatt tttaaataga aagacatttg ggttaaattg
     1441 tgagataata ataaagaaga gtttaaagcg caccccaaac cacttcccca taagtgtgtt
     1501 acgctttaaa ctcttttata tttgaagcca ttaaaaagca taccatattt ttgaaaaaaa
     1561 gtgagaaaaa aggcttacaa ttggagtggt agttaattag tgacttattt ttgattttat
     1621 agcactgata ctataaaata tagatatcat catattacac aatcttaata ctaacttaaa
     1681 aaatatctcc tttcacaagt atggtgataa aattcgttcc gggctacctt tttaggtagc
     1741 ctactttaat ctttatacct ttctggatca acgaaagtat actttatata gtcataacgc
     1801 cgatgatcgc tacgtgcgtc cggcacgtca gtcatgaatc ggctacacta gactagacag
     1861 aaaaaataag gtgtgtagaa taataaaaaa cacactggag gatttttcat g
//
LOCUS       DAFLVO010000182         1859 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.188, whole genome shotgun sequence.
ACCESSION   DAFLVO010000182 DAFLVO010000000
VERSION     DAFLVO010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.188"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            416..1804
                     /gene="ltrA"
                     /locus_tag="L1U99_003009"
     CDS             416..1804
                     /gene="ltrA"
                     /locus_tag="L1U99_003009"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBN1213500.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
BASE COUNT          654 a          343 c          444 g          418 t
ORIGIN      
        1 aacttggtgg tgaaagtcca ctacaggctt ggcagtagga actgttagcg aaagacaagg
       61 cggcaatcgt gaggttgtgg ctgaaggaag tcggacgcaa actcctgaac tgacgaacag
      121 aaactagata caaggctgaa ttaggtcgga taagtcttca tcacaagaca aagtccaata
      181 ctgcccgaaa cctatacagt aaatctagca gttacatggg aggaaagttt tcactcttac
      241 cgggggagat ctcatgaggg tgttgtgggc gttgaatgaa aacaaaccag cacaacgatc
      301 atggcgacat gatggtgaat catgagaagt cagccgaggt catagtagta acgacactga
      361 ccgttacgaa ggactgaaca ataagaatct tgaataattt aggaggtgtg agaagatgcg
      421 acgaccgcag aaaacaagaa aacttggcta tcatcaaaga gctagtgtgg aacacgaagg
      481 gtatgatgaa gtgcgcagca cttcttgcgg tgaacagagg aaacaagatg gtgtagaaaa
      541 tctgtttggg agaattctag atcggaataa tctcaatcaa gcgtatcttc aagtagtcag
      601 aaataaaggg gcggctggtg cagatgggat gaccgtcgat caactgcttc cttacttgaa
      661 agagcaccgc gaggaattac tatccaattt acgccaaggg aactataaac ctcagcctgt
      721 tttgcgagta gaaataccga aaccaaacgg cggtgtaaga aaactaggaa ttcccacggt
      781 tattgatcgt atgcttcaac aggcaatcaa tcaagtgtta caaccgctat ttgaaccaga
      841 attctcagat aatagttatg ggtttcgccc aaatcgcagc gcacatgacg cagtgaagaa
      901 agcaaaatct tattatgaac aaggttaccg atatgtggtg gacattgata tgaaagccta
      961 ctttgacacc gtaaatcacg ataagctgat gtatttcatt gagcggaaag taaaggacaa
     1021 acaagtccta aaactgatcc gtcaatactt aatgagtggt gtaatggaaa atggactcat
     1081 cacaacaact gaagaaggaa cgccccaagg aggcaatctc tctcccctgt taagtaacat
     1141 ctacctgaac gaatttgatc aagtgctaga aaatctagga cataaatttg ttcgatacgc
     1201 cgatgactgc aatatctatg ttagaagcaa acgagcagga cagcgtgtga tgaagaaatc
     1261 cattcaattt ctcgaagaac aactaaagtt gacggtaaat cgagaaaaga gtgcggtagg
     1321 aagtccattg aaacgaaagt ttcttggatt ctgcattctg ccaacaaaga aaggtattaa
     1381 aattcgccct cacgcaaaag caaaacagcg tgtgaaaagc aagctcaaac aactcactaa
     1441 aagaaaccgt ggaagaagta tccaacttat tttaaaagaa atcaagcaac taatgactgg
     1501 ttggatcaac tactatggaa ttggtgagat gaaagaattc atgagggagt taaacggttg
     1561 gttgaagcga agaatcagac aatatatttg gaaacaatgg aagaatccaa gaaccaaaag
     1621 aaaaaatctg attcgtttag ggatcgataa agcgaaagcg tatgaatggt caaatacaag
     1681 aaaaggtatt tggtcagtct ccaaaagtca tattcttcat cgatcattaa cagacaaaga
     1741 actggcccgc caaggatatg aggacatctc cttgaagtac cagttcgtac actcaactta
     1801 ttgaaccgcc gtatacgggt ccgtacgtac ggtggtgtga gaggggcgga aggtcagtt
//
LOCUS       DAFLVO010000183         1847 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.189, whole genome shotgun sequence.
ACCESSION   DAFLVO010000183 DAFLVO010000000
VERSION     DAFLVO010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1847
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.189"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            700..>1847
                     /gene="ltrA"
                     /locus_tag="L1U99_003010"
     CDS             700..>1847
                     /gene="ltrA"
                     /locus_tag="L1U99_003010"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBN1213501.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQK"
BASE COUNT          730 a          281 c          384 g          452 t
ORIGIN      
        1 aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct
       61 gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt
      121 gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag
      181 ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt
      241 cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa
      301 tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg
      361 tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca
      421 gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg
      481 aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta
      541 atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct
      601 caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata
      661 aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa
      721 acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat
      781 gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta
      841 tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca
      901 gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc
      961 aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg
     1021 cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg
     1081 gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt
     1141 agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc
     1201 tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc
     1261 tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac
     1321 aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt
     1381 acaataacat atccagagaa aggaactccg caagggggaa taatatcccc actactagca
     1441 aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt
     1501 acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac
     1561 aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt
     1621 agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg
     1681 attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga
     1741 aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta
     1801 gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaaga
//
LOCUS       DAFLVO010000184         1837 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.190, whole genome shotgun sequence.
ACCESSION   DAFLVO010000184 DAFLVO010000000
VERSION     DAFLVO010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1837
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.190"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            450..782
                     /locus_tag="L1U99_003011"
     CDS             450..782
                     /locus_tag="L1U99_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBN1213502.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            1401..1742
                     /locus_tag="L1U99_003012"
     CDS             1401..1742
                     /locus_tag="L1U99_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HBN1213503.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT          640 a          248 c          401 g          548 t
ORIGIN      
        1 attgattttc gttttgcact tttggatgat aaatttggac aattgaaaat acaaaaaaaa
       61 gaaaggcggt atgaactcgg aaggctggta accttcgtca gcgttcatac acggcattaa
      121 gatttggccc ttaatgcgtt aacctttcag tgttacggta ttacccgcaa tggatttagt
      181 ataacagata ttcaaaagtg ataccacttt ttttggctgt gttaaggtta aaaatacgtg
      241 atattacgat gaatctatgc ctaagcataa tgttataaaa atgtccgtgt ggctctttgc
      301 cgtatgacga acgctgaaat tagagggaac gcatgtttgg atgcgttccc tcttttttgt
      361 ttgtcatgaa cgaaaatcaa ttctctattt ttgaaaaata acaagaaaaa cttgttaaaa
      421 atatttaaag aaattgggtg gtttatttta tgtcatatac aggaattttg agtctcaaag
      481 atatttgtca ctacggtaaa cggtgtaccg ctacagagaa aatcacgaag aaactatcaa
      541 ctggccaaag taaaaccgtt gtgcagtgta agaaatatat aatccagaaa gacaaagtct
      601 cagaggaaat gatttattac attgggaaac aaaagcaaat aattttaaaa gatcctatcc
      661 ccttaaaaga gctatatcca acaatcaaac atgtttatga ccaaaacggt gtactgattg
      721 gtcgaagaaa aaatggagtc ttgcgttgta ccgcaaaagg gatggggcgt ttgatcggct
      781 gaattgatca ttctcataac ttgtatttta tcgtttttcg cttgcttgaa aatattgtcg
      841 agacttctaa aggaacttag agtcactaga aaaataagga gtagacttga tctatcaaca
      901 attcccttcg gggagtgacg gggtaggttt taacgattgg taacgtaaaa aattggtcaa
      961 tcgagtaaat gcgcttgttt ggatagtggt gaaatgaatt tgtgtaaata ataagcgcag
     1021 agtaaacaag agggaattta gaagttagac aagttagaat agcgtctaga ttaatcatga
     1081 gcagctacta agggatctag actttgacgc aaactcatgg aataaggagt aggtcttctc
     1141 gtaatgggga ggacgcacaa gaaattgtgt cgtgtgctgc agtacatgta gatacttgcg
     1201 aggacgttga ttattggatc aatcgagcat ttaccgctgt ctactagggt ttctcgtttc
     1261 ggacgccata aacgagtcga aattttttat gtatttttaa gtaaacgaaa aacgataaaa
     1321 tatgaacaag tcctgaataa agtgaaaaaa ttgatataaa acatagagaa aatgaaattt
     1381 acgtaatgga ggaatgacaa atgaaaaatt atgatccgaa tatacgattg ggcacacata
     1441 ctattaaggt ttctttccaa cgttgggatt acaaaggatt tgtgacgttt agaaggggcg
     1501 gaaattgtaa aggattagat gttttagcat tagacgagga tgatttatac gatcaaacat
     1561 tgactgataa tccaattgga ttcggcttgc tacctgaaga tgatgaaggt aatgaatggt
     1621 ttaaaatgac gcttatgaat gataatggag acgaattatc tgttgaagat acttggtcat
     1681 atttgagtga ttatattgtc agctttgaaa tcattgaatt tgtagcggat aaagaagaat
     1741 aaaaactgga ggaataaatt ttacagataa aggcttagaa ggagtcacga cgattaataa
     1801 aaaggtagta ttaccttagg cattgagtaa ggaattt
//
LOCUS       DAFLVO010000185         1816 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.191, whole genome shotgun sequence.
ACCESSION   DAFLVO010000185 DAFLVO010000000
VERSION     DAFLVO010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1816
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.191"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            77..1642
                     /gene="guaA"
                     /locus_tag="L1U99_003013"
     CDS             77..1642
                     /gene="guaA"
                     /locus_tag="L1U99_003013"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBN1213504.1"
                     /translation="MSSPTRFDEEPKIIVLDYGSQYNQLITRRIREFGVFSELMSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDEKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGK
                     VKPAKNREYGKAELEITSAEAALFQNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCP
                     IASIQNAERKMYGIQFHAEVRHSEYGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGK
                     FGLNIIKVDAKERFLSKLAGVSDPEEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGELTEEKLEIVRESDAILREEIANAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
BASE COUNT          557 a          378 c          386 g          495 t
ORIGIN      
        1 aggtctgatc tttgaaaact aaaaaaatat gcggcgcaca gaacgcgccg catatcggac
       61 taagttttat tcaaatttgt cttcaccaac acgatttgac gaagagccaa aaattatcgt
      121 acttgattac ggtagtcagt ataaccaact gatcactcgc cgtattcgtg agttcggtgt
      181 tttctcagag ttgatgagcc accgcattac cgcagaagaa gtaaaggcaa tgaaccctaa
      241 aggaatcatc ctttctggcg gaccaaacag tgtttatgat gagaaggcct ttggtattga
      301 tgaaaagatt tttgatttgg ggatcccagt tttaggaatc tgttacggta tgcagttgat
      361 tacttataaa ttaggcggaa aagttaaacc agccaaaaac cgtgaatacg gaaaagcaga
      421 attggaaatc acttctgcag aagcggccct tttccaaaac actcctgaaa aacaaaccgt
      481 ttggatgagt catggtgacc tagttaccca agcaccgact gatttcgatg tcgttgctac
      541 cagcaaagat tgccccatcg catcgatcca aaatgcagaa cgcaaaatgt acggaatcca
      601 attccatgca gaagttcgcc attccgaata tggaaatgac ttgttgcgcc attttacact
      661 agatgtctgc caatgtactg gtgactggac aatggataac ttcatcgaca tggagatcgc
      721 aaaaattcgt gaacaagtcg gtgacaaaaa agttttatta ggcctttcag gcggagtaga
      781 ttcctctgtt gttggtgttc ttttacaaaa agcgatcggc gatcaattaa catgtatctt
      841 cgttgatcac gtattgttgc gtaaaggtga agcagaacaa gttatggaaa gtcttggcgg
      901 aaaatttggc ttgaacatta taaaagtcga tgccaaagaa cgtttcttat caaaacttgc
      961 tggcgtgtct gatccagaag aaaaacgtaa aatcattgga aatgaatttg tatatgtctt
     1021 cgatgatgaa gcaaccaaac ttgccggtga agaaggcgtt tctttccttg cacaaggaac
     1081 cctttatacc gatgtgatcg aatcaggaac tgaaactgcc caaaccatca aatcacatca
     1141 caatgtaggt ggattacctg aagacatgca attcaagctg atcgagccat tgaacacatt
     1201 gttcaaagac gaagtacgtg aattaggtac ccaattaggc atgcctgaca gcatcgtttg
     1261 gcgccaacca ttccctggac caggcttagg tattcgtgtc cttggtgaat tgacagaaga
     1321 aaaattagaa atcgtccgtg aatcagacgc tatcttgcgc gaagaaatcg ccaatgccgg
     1381 tttagatcgc gacatctggc aatacttcac cgtcctacca ggcattcgct ctgttggggt
     1441 tatgggagat ggccgtacgt atgactacac tgtaggtatc cgtgctgtca cttctattga
     1501 cggcatgacc gctgactttg cccgtatccc ttgggaagtc ttgcaaaaaa tcagtgtccg
     1561 tatcgtaaat gaagtcgcac acgttaaccg tatcgtgtat gatattacca gcaaaccacc
     1621 tgcaacagtg gagtgggaat aaagagccaa cataatatgg atgaggaata cctataaatc
     1681 aacattattc aattactaaa gttcctgatt ttcgtaaaaa ataagatggt ttcctaccat
     1741 tttccctacc aaagcccttg ttagattaac tactaacaag ggctttgctt ttattcacta
     1801 cctttatttt cctatt
//
LOCUS       DAFLVO010000186         1815 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.192, whole genome shotgun sequence.
ACCESSION   DAFLVO010000186 DAFLVO010000000
VERSION     DAFLVO010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1815
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.192"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..122)
                     /locus_tag="L1U99_003014"
     CDS             complement(<1..122)
                     /locus_tag="L1U99_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1213505.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGPNEGSS"
     gene            complement(133..330)
                     /locus_tag="L1U99_003015"
     CDS             complement(133..330)
                     /locus_tag="L1U99_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBN1213506.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            complement(353..646)
                     /locus_tag="L1U99_003016"
     CDS             complement(353..646)
                     /locus_tag="L1U99_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213507.1"
                     /translation="MINLGEWGTIAGSITAIVSLILLVIRPVTASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERSR"
     gene            complement(683..820)
                     /locus_tag="L1U99_003017"
     CDS             complement(683..820)
                     /locus_tag="L1U99_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBN1213508.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEAEKIINKDKSA
                     S"
     gene            complement(822..1268)
                     /locus_tag="L1U99_003018"
     CDS             complement(822..1268)
                     /locus_tag="L1U99_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213509.1"
                     /translation="MKNIWKYGRTGGEYAGQVLDDMVMTVPFTDVPPLEGIRADGEPL
                     TIADQMFDPKLNQWIVLVNVLDHNDLNNLKAMYESLENENGDLKQLNAKLMLSDVAIK
                     QENTALKEKADGLAQINSKTMLASFQNSKDIAEIKEQLNPASKGGE"
     gene            complement(1271..>1815)
                     /locus_tag="L1U99_003019"
     CDS             complement(1271..>1815)
                     /locus_tag="L1U99_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213510.1"
                     /translation="TRTPNISQFKYFGEGLKDSNNPNDYSWDVTPEYTEKGLNDAVNV
                     YDPQRVEGLKNFADGIQIAGDKVISENDCTVYTLTKDNSQSFIDGYATFIKHGKEVIV
                     NGTVKFKKAYAFGVPLDDEVPDEFVAKIVHGMLTGPSGTSSVSKAMYVRKDLGTIITN
                     SEFAANEWFTFHGNYWVGEE"
BASE COUNT          505 a          382 c          272 g          656 t
ORIGIN      
        1 gagctacctt cgtttgggcc taaattaaat tcattgttaa tcgtataggc aaacccatta
       61 attggcaata aaaaaagagc cgttaatagg ctcatcgcag taatagtaat tttctttttc
      121 atttgtttcc tcctattttt tcaaattata agccgacacg ccagtgataa cgcctaaaaa
      181 tgttgctact gcattgatag tgagtactgt catatctgtt ccattccatc catacgcttt
      241 gcctagtgtt gcaactaata cagatgcagc tggcaatact gttaaaactg tccatttaat
      301 gacttgataa tacttatcgg gtaaaatcat ttcttcttaa ctcctttctt ttttaccgag
      361 atctttctct aaataaagtt ttgatttgtt gtgtgtgttc taccaatttt tctgtatgtg
      421 tatctaatct ttcatcgtgt ttctttagtt cttcatgaat catcaatcga tctgatttgc
      481 tcgattctaa atctttagtc agcaaatcta aattgtgact tacttttgaa agagtttcag
      541 taatcttcga gaaagatgca gtgactggtc ttattactaa taaaatcaaa gaaacaatcg
      601 cagtgattga tcctgcgatt gttccccatt ctcctaaatt aatcatgtga caactccttt
      661 accttaaata aaaacgcatc acttaagatg cgctcttatc tttattaatg attttttctg
      721 cttcttcgtc tgtaatgcat agtggaacga atagtcgaac ttgatcgtca gtaaaacagc
      781 cccaatcata catcattttc acatcgctaa aactaaacat actactcacc tccctttgaa
      841 gctggattta gttgctcttt aatttctgca atgtctttgc tattttggaa cgaagcaagc
      901 atcgtttttg aattgatttg tgctaaacca tccgcttttt ctttcaatgc agtattttcc
      961 tgtttaatcg ctacatcgct tagcatgagt ttggcgttga gctgttttaa atcgccgttc
     1021 tcattttcta acgactcata catcgctttg agattgttta aatcgttgtg atctagtaca
     1081 ttcactaaaa caatccattg gttcagttta ggatcaaaca tctgatcagc aatcgttagt
     1141 ggttccccat cagcacgaat tccttcgagt ggtggaacat cggtaaatgg aacagtcata
     1201 accatatcat caagcacttg tccagcatac tctccacctg ttcgtccgta tttccaaata
     1261 tttttcattt ttattcctcc cctacccaat aattaccatg gaatgtaaac cattcatttg
     1321 cagcaaattc gctattcgta ataattgttc ctaagtcttt tcgcacgtac atcgcttttg
     1381 atacactact tgttcctgac ggacctgtaa gcatgccatg aacaattttt gcgacaaatt
     1441 catctgggac ttcatcatca agtggtacac caaaagcata agcttttttg aactttactg
     1501 taccatttac aataacttct tttccgtgtt taataaatgt tgcataccca tcgataaacg
     1561 attgactgtt gtctttagtt aatgtataaa cagtgcaatc attttcactg atcactttat
     1621 ctcctgctat ttgaatacca tcggcaaagt ttttcaaacc ttcaactctc tgaggatcat
     1681 acacattaac agcatcattc aagccttttt cagtatattc aggtgtgaca tcccaactgt
     1741 aatcattggg attgttactg tctttcaagc cttcaccaaa gtatttaaac tgactaatat
     1801 tcggggttcg tgtgt
//
LOCUS       DAFLVO010000187         1785 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.193, whole genome shotgun sequence.
ACCESSION   DAFLVO010000187 DAFLVO010000000
VERSION     DAFLVO010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1785
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.193"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            211..807
                     /locus_tag="L1U99_003020"
     CDS             211..807
                     /locus_tag="L1U99_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBN1213511.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
     gene            complement(865..1347)
                     /locus_tag="L1U99_003021"
     CDS             complement(865..1347)
                     /locus_tag="L1U99_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213512.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(1453..1650)
                     /locus_tag="L1U99_003022"
     CDS             complement(1453..1650)
                     /locus_tag="L1U99_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213513.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
BASE COUNT          602 a          362 c          270 g          551 t
ORIGIN      
        1 ttttcaaata agcaaaaatt cctaaaacac aacaatgaaa gcgataacta agaaaatcct
       61 tacataacga tttttcttat taaaattgtt ttttgaactt cgcttatttt ttgtgagcat
      121 atctgtttac ttactttttg taaggtgcta tacttcattt cgtaatcaat taaaaaaatg
      181 caaaacgcaa atcaaaggag aaattttatt atgacaactt ttactgacac tttgaaaaac
      241 cgccgttcaa tctatcatct aggacgtaat gtttcacttt ctaatgaaga attaacaact
      301 ttgatcaaag aagcaattaa agaaagccca actgctttca atgctcaatc aacacgcgca
      361 gttatccttt tcggagatgc acatgaaaaa ctttgggaaa tcactgaaga agcacttcgc
      421 ccattgactc cagcagaagc tttcccaaat acacaaaaca aattagctgg tttcaaaaat
      481 ggttatggta cagtattatt cttcaaagat actgacgtgg taaaaggtct acaagaacaa
      541 tttgaattat atgcagacaa cttcccagat tggtcagaac aatcaaacgg aatcgcaaca
      601 gctaatactt gggtagcatt agttgataaa ggattgggcg caaacttgca acattacaac
      661 ccagttattg acgaagcagt tgcaaaagaa tggaatatcc cttcaaactg gaaactacgt
      721 tcgcaattag tattcggttc accagaaaca ccggctgagg aaaaagaata catgaacgat
      781 gccgatcgct tccgcgtatt tggataattt tatttgaaat aaaaaacaga ggttgtgaca
      841 aacatcttgt cgcaacctct gtttttattc tggatcaatc ataatatcaa tctctgcctc
      901 atcgtttaag cgttgggaca aaaatggaac taattcttct aatgatgcag aaaatttcag
      961 catcggtcct cgccatccgt ttcggaaaaa attcattttt acgattttag aaccttttgg
     1021 ctgatataat acaattttat tgatctcaga aaaaggaaca ccttttttgt caaagctatt
     1081 caaaacaagt ccttcttctg tgattcctct actgtccaac aaaaaactaa taaaaatcat
     1141 tgctgacaag atcccttttg ccaattcatc tgctgtagga tgactgatga gtgtatacca
     1201 aatgactagt gacactaaga agggtatcac caagtagacc catcgatttc gcacagtccg
     1261 ataaataatt tcttttcgaa ccagccaaag aaataaaaac atcacaacaa cgaataaaaa
     1321 caatagaacc gtaaagaatg ttaccatgac aactcgcctc gctttttctt ctccagaaaa
     1381 taggaaaaga atactgattt accttctcaa agaaattgga cttgcagcac gccgcacgtc
     1441 caattgtttt ctttattcaa atgtatcata ttttgcaaca accatgcttg ctttttcatc
     1501 taataattct tggtcctctg cagcacattg ggcaactttg accacggcgc agtttgtcat
     1561 ttttgataca acttcaccaa tgaccgtttt tgtaaaacca attggtttgc atgcatattg
     1621 ttctcctaaa ttaatcattt cttccgtcat caaaatcctc ctaaactgct ggaacttttc
     1681 tccacattac cactgctatt tctttggaga tttaactcat tgatttttat ttacagttaa
     1741 aaatcaacct tacaggcatt atagcgtact gttttcgttt tcaca
//
LOCUS       DAFLVO010000188         1734 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.194, whole genome shotgun sequence.
ACCESSION   DAFLVO010000188 DAFLVO010000000
VERSION     DAFLVO010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.194"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..1450
                     /locus_tag="L1U99_003023"
     CDS             <1..1450
                     /locus_tag="L1U99_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBN1213514.1"
                     /translation="EVTDNRSDADKYEPTVEGEKVEVGGTVDLTDNVTNLPALPEGTT
                     VTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEK
                     VEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTV
                     KVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYAWKEKVDVS
                     TAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSDADKYNPEGQKVTTDLNKEPDASEGI
                     KNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVTYPDGSKEEVEVTISVVDKKAPNKPQ
                     VDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHGTADKNGNFTVKVPKLEAGTKVIVTA
                     TDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTDNQGSNSNQDKNRGKSQSSKVFPKTG
                     ESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1584..>1734
                     /locus_tag="L1U99_003024"
     CDS             1584..>1734
                     /locus_tag="L1U99_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBN1213515.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIK"
BASE COUNT          684 a          261 c          373 g          416 t
ORIGIN      
        1 agaagtgaca gacaatcgtt ccgatgccga taaatatgaa ccaacagtag aaggcgaaaa
       61 agtagaagtt gggggcacag tagatctaac agataatgtt actaacttgc cagcgttacc
      121 agaaggaaca acagtaacag atgttactcc cggcggtaca attgatacca acacaccagg
      181 taattacgaa ggtgtcattg aagtaacgta tccagacggt acgaaagata cggtgaaagt
      241 tccagtagaa gtgacagaca atcgttctga cgccgataaa tatgaaccaa cagtagaagg
      301 cgaaaaagta gaaattggag gcacagtaga tttaacagat aatgttacta acttgccagc
      361 gttaccagaa ggaacaacag taacagatgt tactcccggc ggtacaattg ataccaacac
      421 accaggcaat tatgaaggtg tcattgaagt aacgtatcca gacggtacga aagatacggt
      481 gaaagttcca gtagaagtga cagacaatcg ttctaatgca gataaataca atcctgaagg
      541 acaaaaagtg actacagact taaataaaga gccagatgca tctgagggaa ttaagaacaa
      601 agaagattta ccaaaaggaa ctacttatgc ttggaaagag aaagtagatg ttagcacagc
      661 tggaaataaa aaaggtacta ttgtagtgac atatccagat ggatcatctg atgaagttga
      721 agtagacgtt acagtgacag atactcgttc cgatgcagat aaatataatc ctgaaggaca
      781 aaaagtgact acagacttaa ataaagagcc agatgcatct gagggaatta agaacaaaga
      841 agatctacca aaaggaacta cttatacttg gaaagaaaaa gtagatgtta gtacagctgg
      901 aaacaaaaaa ggtactgtag tagtaacata tccagatgga tctaaagaag aagtagaagt
      961 tactatttct gtagtagata aaaaagcacc gaataaacct caagttgatc ctattacaga
     1021 gggtgaccaa attgttactg gtaaaactga accaaatgca gaggtgacag ttacattacc
     1081 agacggaagt caacaccatg ggacagctga taaaaatggt aattttacag ttaaagttcc
     1141 taaattagag gcagggacaa aagtgatagt aactgcaact gatgaatctg gtaatactag
     1201 tgaacctact aatgtagttg tttcttccaa caaaaaagac agtggaaaaa acggtagtaa
     1261 aggtagtaag actgacaatc aaggtagcaa cagcaatcaa gacaaaaata gaggcaaaag
     1321 ccagtcctca aaagtttttc ctaagacggg agagagtgac agtaatatct ttactattag
     1381 cggtggttta atactgttag gaacgttagg attattaggg tataaaaatc gaaaaaaaga
     1441 gaatgaatag aaaatcaatt tcttaagtct tctctgagaa gaggaagaat ctttttcttc
     1501 ctctttttgc ttttttatga tgggaaataa gtgttagtta aagatgaata tactttttat
     1561 agaaaggaaa agaatgtaat taagtggaaa aaatagtaat tattggttca aaccattcag
     1621 ggctagccgc agctcgattt ctaaacttaa gcgattcaaa ttatgaagtt attctaatcg
     1681 ataaaaaatc agaaattagt tacttggaat gtgggacatc gttatttata aaag
//
LOCUS       DAFLVO010000189         1729 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.195, whole genome shotgun sequence.
ACCESSION   DAFLVO010000189 DAFLVO010000000
VERSION     DAFLVO010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1729
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.195"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..900)
                     /locus_tag="L1U99_003025"
     CDS             complement(<1..900)
                     /locus_tag="L1U99_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HBN1213516.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYKKFKRYF"
     gene            complement(1059..1325)
                     /locus_tag="L1U99_003026"
     CDS             complement(1059..1325)
                     /locus_tag="L1U99_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1213517.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            complement(1315..1671)
                     /locus_tag="L1U99_003027"
     CDS             complement(1315..1671)
                     /locus_tag="L1U99_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBN1213518.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
BASE COUNT          501 a          330 c          207 g          691 t
ORIGIN      
        1 aaaatacctt ttaaatttct tatagtcctc tgaaatcaaa atatagcgtg atggatactc
       61 atcaaaagaa gaatcgtatt cttcctttaa aattcccgat ttacttaatt tttctagtac
      121 atcaaatact ctatcactca agtaactcct taaattgtta tcactttccc attgaactac
      181 ttttctataa gttgaattat cagttgaaaa gatagaattt tcatccataa acgcatatat
      241 tagcagcaat ctttcatcat tgtcaaattc tattggatca aaaatatcta agttgtcatc
      301 aaaatcttta tcagttccgg taactttttt gttaattact gaaggtgtct tgtaagaaat
      361 agaatctaaa tcaaagcgtt ttgattctaa attattttgt gctttctcaa ttaaataatt
      421 cacttttttt gtgagaaacc ttctgatatt gtctttgcta tatgttccat aaaaaccctt
      481 atcttctaaa gagtccctgt acttcttaac ttctatatac tcttcagcca aaacttgtgg
      541 aactggttca tctaagaaaa aaacccctac ctcgcctttg ctatttttat aaaagtaatc
      601 aatttctgct atagttcccg atctataatt atcaactgga gaacccaact tatggccaaa
      661 aatcgctaat aatatatcac tattttctac aatttgttta ttaataacac tttgcccaga
      721 gctattattt atataagtag gaatcgcatt cgtttcccat cgaattggca tcaaaattac
      781 ttttgtatta tctgtatttt ctatattcca tctatatatg gtttcttcta cttcattcct
      841 ctttgctgct atatcacctg gtgatgctat aaatactttt attagattta tggttttcat
      901 ttattgtacc tttctcttta tgtctcttta aagtaatttt tgtataaaat ttattgactt
      961 ttacactata ggacaacttt tatctattta gtacaaaaag gcccactaaa ctaattgatt
     1021 agttaggagc ctattacagg tatattttca actcgctttt aagcaaattc tactaccagc
     1081 tttttgccta atgccctagc gatatcatca agtttatcga aagatacgtt atcccctctc
     1141 tcaattcgag caatagtaga ttgagttgta tgtgcttttt gtgcaagctc cgcttgagtt
     1201 aggcctgctt cctcccgtgc atgataaaga gcaaccgcag tttcgagttt tcttccttca
     1261 cggtcatatg cttctgcaaa atctttgtct ttttgctttt cttcaatcaa ttttttaatc
     1321 atcatttgtg aaccactcct ctctaagttc ttttgcatgt ttaagttcac ttattggtgt
     1381 tttctccgtt tttttagtaa atccatgggt aatgacatac cttccattga ccacatggaa
     1441 atagatagct ctttggatgt ttgatcctac cttacttctt aattcgtaca aattagtgtc
     1501 taattttttc acccatttca accgttgagc tactagcatc ccattctttt ctgtttcttc
     1561 tattgtacgt aaaagcttcg cactatcttt ttttggtaat gtttccaacc attctaaaaa
     1621 ttcatcatga ccattaggtc ttttaaatgt ttcaaaagat attttttcca tacccaatta
     1681 tatcatatat tgattttata ttatagtata taacataaaa attcgaatt
//
LOCUS       DAFLVO010000190         1664 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.196, whole genome shotgun sequence.
ACCESSION   DAFLVO010000190 DAFLVO010000000
VERSION     DAFLVO010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.196"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            131..505
                     /locus_tag="L1U99_003028"
     CDS             131..505
                     /locus_tag="L1U99_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBN1213519.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="L1U99_003029"
     CDS             complement(619..1248)
                     /locus_tag="L1U99_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBN1213520.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="L1U99_003030"
     tRNA            complement(1382..1454)
                     /locus_tag="L1U99_003030"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
BASE COUNT          584 a          240 c          283 g          557 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt actt
//
LOCUS       DAFLVO010000191         1647 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.197, whole genome shotgun sequence.
ACCESSION   DAFLVO010000191 DAFLVO010000000
VERSION     DAFLVO010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1647
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.197"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            75..1598
                     /locus_tag="L1U99_003031"
     CDS             75..1598
                     /locus_tag="L1U99_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBN1213521.1"
                     /translation="MDPTVFEAEEHIQKVIHKMFRPDNAYTKFDFRNGRPTKSAILTT
                     SSIDMAKKYYRAIKEMTKESDWLIKEFPNQPIREGRTMEDPDFPRIAITYSLEENSRD
                     SSAQQEEMQKIIEEYNQYYDTAWSLADIERYNGDINNRLARKRAEFKQFGKQIDLVIV
                     VDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTYPEKTKGLIVTFRKPATMEKN
                     VEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKEVSSMESIDEHTPLEIRIEYV
                     KAFQELNRAYESLVTYDDYNDDMVQSSTLNNQIQLLEEQIGVYETVKGSLMEEEPEKE
                     GEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSDAREEIEKALAKLNKTEGVKE
                     VYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDNLIHAFSNEWFVSEKELHASNLQYM
                     PGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMKRAWRKMLDDELIPLENELR"
BASE COUNT          602 a          269 c          338 g          438 t
ORIGIN      
        1 catatgcaga gtattcaccg gaacagatca atcgtatgat cgatcaaatg gagtctgtca
       61 aaaaagaaag ttatttggac cctactgttt ttgaagcaga ggaacatatc caaaaagtca
      121 ttcataaaat gttccgtcca gacaatgcct atacaaaatt tgattttcga aatggccgtc
      181 caacgaagtc tgcgatctta accacgagtt ccattgatat ggccaaaaag tattatcggg
      241 ccatcaaaga gatgacgaaa gaatctgatt ggttaataaa agagtttccc aatcagccta
      301 tccgtgaagg acgaacgatg gaggatcctg atttcccacg aatcgctatt acctattcat
      361 tagaagaaaa tagccgagat tcaagtgccc aacaagaaga aatgcaaaaa attattgagg
      421 aatataatca gtattatgat actgcctggt cactagcaga cattgagcgt tataacggag
      481 acatcaataa tcgtttggca cgaaaaagag cggaattcaa acaatttggg aaacaaatcg
      541 atttagtaat cgtagtggat cgtctattga caggttttga cgcccctacg attcaaaccc
      601 tatttgtgga tcgtaatcta gagtatgcag gattgatcca agccttttca cgtacgaacc
      661 gtacgtatcc tgaaaaaaca aaaggactaa ttgttacttt ccgaaagcca gcgacaatgg
      721 agaagaatgt cgaggatgcg acaaaactgt attcagaagc taaagaagaa tcgggtttga
      781 tttatccaag ttaccaagaa tccaaaaaaa gattcaagca agcatatggt aagttaaaag
      841 aggtttcatc catggaatcc attgatgaac atacgccact tgaaatccgt atcgagtacg
      901 tcaaagcatt tcaagaattg aatcgtgcgt atgaatcgtt agtgacttat gatgattaca
      961 atgatgacat ggtgcaatct tcaactttga acaatcaaat tcaacttttg gaagaacaaa
     1021 ttggcgtgta cgagaccgtg aagggttcat tgatggagga agaaccagaa aaagagggag
     1081 aagatttttc aacgatcgaa ttttatagtg aaaataccac taagttgtat gatattgatt
     1141 ctacttatat tgatcaatta ctaggaactt atgctgcgaa tagttcagat gcacgagaag
     1201 aaattgaaaa agctttggct aaattgaata aaacagaagg agtcaaagaa gtttaccgac
     1261 aaattttaaa tgcatttgat gtggggactt tagatagtaa tgaagatatc tttgtcatta
     1321 aacgtcgcta ttttacacaa gcaagtgata atttgattca tgccttttcc aatgagtggt
     1381 ttgtttctga gaaagaatta catgcttcta atctgcaata tatgccaggt gaagatccaa
     1441 ttcctaatat gaaagcaatt atcaacagta aggattacga aggatataaa gccaaacatc
     1501 cagaagcgaa accatttaaa tacccacaag aaatgaagcg agcatggcgt aaaatgttag
     1561 atgatgagtt gattccactt gaaaatgaat tgaggtaaac gagaagagtt aagaaaattg
     1621 tacgattcaa agatagtagt aaagtgg
//
LOCUS       DAFLVO010000192         1628 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.198, whole genome shotgun sequence.
ACCESSION   DAFLVO010000192 DAFLVO010000000
VERSION     DAFLVO010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1628
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.198"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            98..955
                     /locus_tag="L1U99_003032"
     CDS             98..955
                     /locus_tag="L1U99_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBN1213522.1"
                     /translation="MEEKLIKKDEIIMGLLVPRANTYTIPLTKRQLIAKRYQRITRAI
                     NREFWNSESDTAHSLYVGSYGRGTAISTSDIDIIVELPMAEFDRFKNYLSNGPSKLLQ
                     VIKNAFQEILPNSDIRADGQVVKINFHDGIKFEIVPAFNEKDYLGESKGFIYPDSNMG
                     GNWKATNPKKEQEAMKLKNTKSNNLLYATCKHFRHVRDTEFTSYHLSGIVIDSFVYEA
                     MGNWKFVENNSGGQNISSVSYETALLEYYNSHKVMGGLNLYSPGSNQFVNSDSSIICL
                     EKVLKKIAL"
     gene            975..1535
                     /locus_tag="L1U99_003033"
     CDS             975..1535
                     /locus_tag="L1U99_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HBN1213523.1"
                     /translation="MGDEKKRLEVQLREAYGRVTYTYTTHLKQADNIISDNKILRCLQ
                     IGLSALTTGGVLSTIITDNSELTFVAGLCSTISLGLNLYFKNFDLAEEAKNHQIVADK
                     LWLIREEYVSLLTDLNRLSVEDIVKKRDQLMNKTHEAYKNAPKTNSKSYESAQKALKS
                     EEEQFFTEEELDKMLPEHLRKKSSKY"
BASE COUNT          630 a          197 c          283 g          518 t
ORIGIN      
        1 attattgtga aatatttccc tttaattaat caaatttttt ataaaagtaa tatataaaat
       61 aaattgcttg aagtattata tttagatatc ataatttatg gaagaaaaat taattaaaaa
      121 ggatgagatt ataatggggt tactggttcc gagagctaat acttatacta tacctttaac
      181 gaaacgccaa ttaattgcta aaagatatca aaggattact agagccatca atagagagtt
      241 ttggaattct gaaagtgata ctgctcacag tttatacgta ggttcttatg ggagaggaac
      301 ggcaattagt actagtgata tagatataat agttgaatta ccgatggcag aatttgacag
      361 attcaaaaat tatttatcaa atggaccgtc taagttatta caagttataa aaaacgcatt
      421 tcaggaaata ctaccaaata gtgatattag agctgatgga caagttgtta aaataaattt
      481 ccatgatgga atcaaatttg aaatagttcc agcttttaat gaaaaagatt atttgggtga
      541 gtcaaaaggg tttatttatc cagattcaaa catgggaggg aactggaaag ctacaaatcc
      601 caaaaaagag caagaagcca tgaaattaaa gaatacaaaa agtaataatt tattatatgc
      661 tacgtgtaaa cattttcgac atgtacgaga tacagaattt acgagttatc atctttcagg
      721 aatagtaatt gacagtttcg tatatgaggc tatgggaaat tggaaattcg ttgaaaataa
      781 cagtgggggt caaaacatta gttctgtatc ttatgagaca gctttattag aatactataa
      841 ctcacataaa gttatgggcg gtttaaattt atactctcct ggaagcaatc aatttgttaa
      901 ttctgatagt agtatcatat gtttagaaaa agtattaaaa aaaatagctt tataaagttt
      961 tatggaggaa caacatggga gacgaaaaaa agcgcttgga agttcaatta cgtgaagcat
     1021 atggacgagt aacgtatact tacaccactc atttaaagca agccgataat attatttctg
     1081 acaataaaat tttaaggtgt cttcaaattg gtttgtcagc ccttactact ggaggggtac
     1141 ttagtaccat tattactgat aatagtgagt taacctttgt tgctggatta tgttcaacaa
     1201 tttctcttgg attaaactta tactttaaga attttgatct tgctgaagaa gctaaaaatc
     1261 atcaaattgt tgccgataaa ttatggttga tcagagaaga atacgtaagc ttactaacag
     1321 atttaaatcg tttaagtgtt gaagatattg tgaaaaaaag agatcaatta atgaacaaaa
     1381 ctcatgaagc atataaaaat gcccctaaaa caaatagtaa aagctatgaa tcagctcaga
     1441 aagcattaaa atctgaagaa gagcaatttt ttacagaaga ggaattggat aagatgttac
     1501 cagagcatct tagaaaaaag agttctaaat attgaactct ttttttatgc ttaaaatttt
     1561 cttgtaattt ttctattcaa tcaataaata atctatattt aagaagaaat atgatgatag
     1621 aaacatct
//
LOCUS       DAFLVO010000193         1628 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.199, whole genome shotgun sequence.
ACCESSION   DAFLVO010000193 DAFLVO010000000
VERSION     DAFLVO010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1628
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.199"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..767
                     /locus_tag="L1U99_003034"
     CDS             <1..767
                     /locus_tag="L1U99_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBN1213524.1"
                     /translation="REKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKI
                     TEEKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEK
                     ELYANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRL
                     EPMDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVS
                     LDEIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            839..>1628
                     /locus_tag="L1U99_003035"
     CDS             839..>1628
                     /locus_tag="L1U99_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1213525.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQDMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNGVS
                     LARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGELI
                     SLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKE"
BASE COUNT          706 a          188 c          258 g          476 t
ORIGIN      
        1 ctagggaaaa aatcataaaa atatttgata aaattaataa tttattcaag aatgacaatg
       61 ctgaattaag gaagggtctt ttagagttta aacttcaaga actagaactt cattactctt
      121 atttagtgaa aattaccgaa gaaaaagaac aacaaaaagc aataaaagaa cagatgatag
      181 aagaggaaaa agttcgtaga gaaattgatc gtgaaaagaa acgtattgat aaagaacaac
      241 gtcaattcaa ttctgaaatt tccaaattaa tcgcatatat gcaaaaagct aatgcagatg
      301 tggaaaaaga attatatgca aataaaattc aagaactgga agaaaaatta aaagaattag
      361 aagttatacg tgaaaatgta ttacaaagag aattaaatac tagagccggt tatgtgtatg
      421 taattagtaa tattgggtct tttggtgaag acatatataa aattggtatg actagaagat
      481 tagaacctat ggatagaata aaagaattga gtagtgcatc ggttccattt gaatttgacg
      541 ttcatgcgat gattttttca gaggacgctc cgtctttgga aactaaattg cataatcatt
      601 ttagaaaaca agaagttaat aaaattaatc aaagaaaaga atttttcaaa gtttcactag
      661 acgaaataga gaaagttgtt ttagaaaatt ataatggaac agtaacattt acaaaattag
      721 ctaaagctga acaatataga cgatctttag aattgtcaaa agattaaata tataaaaagc
      781 cttcgggctt tttcttttaa caattaatag gaacgtatat tcgaaaggaa tagaaataat
      841 gtggttagaa aaaataaatg acaaaaaatt taagtacacc gaacgttata cggatccctt
      901 aactgaaaaa aagagaaaag tgtccgttac tttatctagc aattcacgcc aagcttggaa
      961 tcaagctaac ttacttttga atgaaaaaat cgcagaaaaa ataaaacgaa atgaagaatt
     1021 accactaact tttggagaat taaaaactaa atgggatgaa aaatacaagc caactgtaaa
     1081 agaaagttcc tatcgaacaa ctcaggttta tctatcatta atttcaaaat atataaaaga
     1141 tgatgtactt gtaaaaaacg ttaatagtaa tcttatacaa gatatgctag attactacta
     1201 ttttgaaaaa aatttatcat ataattatgt aatacattta aaaactttta caggaatgat
     1261 ttttaaattc gccaaccgtc gatatggatt aaaatataat cccgtaaatg gggtttcttt
     1321 agcaagaaaa cctaagacaa acgaagaaat aaaaaaagaa aaagatggtt atttatcaaa
     1381 agaagaagtt caaatgattg ctagtaaaca aaaaagttca catcaacagt cacgttattc
     1441 tttaattact aaatttttgt ttttaactgg actacgttat ggtgaattga tatctttgac
     1501 tgaatctgat tatgatggta ataaaattac ggtttctggt acttatgatt acgagttaaa
     1561 aattaaaaca acaactaaaa atacaggttc ttatagaacc attgaattat caagtaatgc
     1621 taaagaaa
//
LOCUS       DAFLVO010000194         1593 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.200, whole genome shotgun sequence.
ACCESSION   DAFLVO010000194 DAFLVO010000000
VERSION     DAFLVO010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.200"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(283..813)
                     /locus_tag="L1U99_003036"
     CDS             complement(283..813)
                     /locus_tag="L1U99_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213526.1"
                     /translation="MSQNISAVKQLIEEDLETTVQRLAERIHFANYQTISNWSSRNRN
                     PEEIPMKFFYRIGKEYGVDPIKIFEKTMIYYYHGTPNEVLEHLLEEAKEKSSILELSQ
                     NDKVIQVKCVDPTGKIIVGFDIERKSKIDFITQLKKINNLDILTLRPDHEQLFMSFKK
                     QLKEIQKRYNKVFPNA"
     gene            complement(829..1194)
                     /locus_tag="L1U99_003037"
     CDS             complement(829..1194)
                     /locus_tag="L1U99_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213527.1"
                     /translation="MSSLKDDYIQAKQEYEKIQMLKSEKVELFLTQKLAEDHIANLDA
                     KTLEEYDRQFNQIHHNIILLVEQAKRRFEKAEYDLLDQGIVCLDKGLRRYYGAELKKQ
                     NVDRNALKHEILELIMQRI"
     gene            complement(1200..>1593)
                     /locus_tag="L1U99_003038"
     CDS             complement(1200..>1593)
                     /locus_tag="L1U99_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213528.1"
                     /translation="KWKTEIYPSLNDYKTSGKPMYNYTGFLTYTQYKYAFRKLKGIKQ
                     AEIALYEMKKVDRLKLIQDLVQNTWNQAIVELEKENGKILTNKYLIVNEIEELIGLFS
                     CEKGEVFLKSSPTYSILDSPYQFIQARR"
BASE COUNT          452 a          302 c          201 g          638 t
ORIGIN      
        1 ctattacgtt gttagcagaa acttcaaaat aggattgttc cctttgtatc ctcataccaa
       61 tcatcatagc gcaggaaata actattaata acaatcctgt ttttaatcta ttattccaca
      121 tgcagtttcc acatccttat cttgataaaa atcctcttga ccctctccaa ttactgtttt
      181 aaatataacc accaaaacaa gatcatgcta agaaatccaa gagtatataa gatgatacat
      241 tctttgttaa ttatccaaaa aactctgatt tctttgagct tttcacgcat taggaaacac
      301 cttgttatat cttttttgta tttctttcaa ttgtttttta aaactcataa acaactgttc
      361 atgatctggt ctaagcgtta gaatatctaa attatttatc ttttttaatt gtgtaataaa
      421 atctattttg gattttcttt caatatcaaa accgacaata atctttcctg ttggatcaac
      481 gcatttcact tgaataactt tgtcattttg cgatagctct aatattgatg atttttcttt
      541 tgcctcttcc aaaagatgtt ctaacacttc gttaggtgtt ccatgatagt aataaatcat
      601 ggtcttctcg aaaattttta tcggatcaac accatattct tttccgattc gataaaaaaa
      661 tttcattgga atttcttccg gatttctgtt cctgcttgac cagttagaga tggtttgata
      721 atttgcaaaa tggattcgtt ccgctaatct ctgaactgtg gtctctaaat cttcttctat
      781 taattgtttt acagcactaa tgttttgtga catttgcttt ctatcccttc aaattcgttg
      841 cattatcaat tctaagattt catgttttag tgcatttcta tctacatttt gcttttttaa
      901 ctctgcacca taatatcttc gcaatccctt atccaagcat acaattcctt gatctaatag
      961 atcatattcc gctttttcaa accttcgctt tgcctgctca acaagcaaaa tgatattgtg
     1021 atgtatctga ttaaactgcc gatcatattc ctctaaagtt ttagcatcta agttagcaat
     1081 atgatcctct gctaattttt gtgttaaaaa taattcgact ttctcagatt tcaacatctg
     1141 tattttttca tactcttgtt ttgcttggat atagtcatct ttcaagctag acatctaact
     1201 catctccttg cctgtataaa ctgatacgga ctgtccaaaa ttgaataggt tggtgatgac
     1261 ttcaagaaga cttcaccttt ttcacatgaa aataaaccaa ttaattcttc aatttcattt
     1321 acgatcagat atttattagt taaaattttc ccattttctt tttctagctc gacaatcgct
     1381 tgattccatg tattttgcac taaatcttga atcaatttca atctatccac ttttttcatc
     1441 tcatacaggg caatttcagc ttgtttaatg ccttttaatt tgcgaaaggc atatttgtat
     1501 tgtgtgtagg ttaaaaagcc tgtgtagtta tacatgggct ttcctgatgt cttgtagtca
     1561 tttaagcttg gatatatttc agttttccat ttt
//
LOCUS       DAFLVO010000195         1588 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.201, whole genome shotgun sequence.
ACCESSION   DAFLVO010000195 DAFLVO010000000
VERSION     DAFLVO010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1588
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.201"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            47..1093
                     /locus_tag="L1U99_003039"
     CDS             47..1093
                     /locus_tag="L1U99_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1213529.1"
                     /translation="MSVKISVIVPCYNVEKYIDECINSLINQTLKDIEIILLNDGSTD
                     NTLAILKKYEKLDSRIKVYEHKNMGLGPTRNRGIKIANGEFLAFVDSDDFVSNTMFES
                     LYNCAIAENADIAIGEVGIFSDREIERVKIRKSLTNLKTIELATYNKKEFFKQFYFNR
                     LYSHNAWDKIYRRSLVLEFNLSFGDNKIIFAEDNWFQLQVFMTNTRICFVDKLCYYYR
                     QQNNSIMHKPKSNLVFRHGNMIADYEKLIRQNGNNIIDKKACMLVAFDVLIMEIFNQK
                     NVGGTCEDYKNALVSLKHHKILRENISNIVRMKAYELEPNMRKKLALVTISIMFNFKM
                     YKTAYNMLWRIYNR"
     gene            1107..>1588
                     /locus_tag="L1U99_003040"
     CDS             1107..>1588
                     /locus_tag="L1U99_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1213530.1"
                     /translation="MRKLTFVIGIMGKGGAERVIANLANNFIQDNWEIDIITIYGNRQ
                     DYELNRKIQVHPIICKSSFRAFRPLERFKELRKKIREIQPDLVISFLADVNIHVIISL
                     LGVKQKLIVSERNDPQRNPEEPWIRKIRDFLYKNVDGIVFQTPDAKKYFSKINDKKVK
                     T"
BASE COUNT          634 a          152 c          291 g          511 t
ORIGIN      
        1 tatttttaat ttatatttat aacaaattga taaagaggta ataataatgt cagttaagat
       61 tagtgtaatt gtaccttgtt ataatgttga aaaatatatt gatgagtgta taaatagttt
      121 gataaatcaa acattgaaag atattgagat tattttgtta aacgatggtt caacagataa
      181 tacgttggcg atattaaaga aatatgaaaa gcttgattct agaataaaag tttacgaaca
      241 taaaaatatg gggttagggc caactagaaa tcgagggatc aaaatagcta atggagaatt
      301 tttggctttt gtggattctg atgattttgt ttccaatact atgtttgaaa gtttatataa
      361 ttgtgcaatt gcagagaatg cggacattgc aattggagaa gtaggcattt tttctgatag
      421 agaaatagaa agagtaaaaa taagaaaaag tctaacgaac ttaaaaacaa ttgaattagc
      481 aacatataac aagaaagaat tttttaagca attctatttc aatcgtttat attcacataa
      541 tgcttgggat aagatatata gacgtagttt agtattagag tttaatttat catttggtga
      601 taacaaaata atttttgcag aagataattg gtttcaatta caagtattta tgacaaatac
      661 aagaatctgt ttcgtagata aattgtgtta ttattatcgc caacaaaata attctataat
      721 gcataagcca aaaagtaatt tggtttttag acatggaaat atgattgctg attatgaaaa
      781 gttgataagg caaaatggaa acaacataat agataaaaaa gcttgtatgt tggttgcatt
      841 tgatgtacta attatggaga tttttaatca aaaaaacgtt ggtggaacat gtgaagatta
      901 taagaatgca ttagtttctt tgaaacatca taaaatattg agagaaaata tttcaaatat
      961 agttagaatg aaagcatatg aacttgaacc taatatgaga aagaagttag cccttgtgac
     1021 cattagtata atgtttaatt ttaaaatgta taaaacagcg tataatatgc tctggagaat
     1081 atataatcga taaagaggta ggaaatatga ggaaattgac ctttgtgata ggaattatgg
     1141 gaaaaggagg ggcagaacga gtaattgcga atttggcaaa taattttatt caagataact
     1201 gggaaattga tattataact atatatggga atcggcaaga ctatgaactg aatagaaaaa
     1261 tacaggtaca tccaataata tgtaaaagtt cgtttcgtgc atttagacct ttggaacgct
     1321 ttaaggaact taggaaaaaa ataagggaaa tacagcctga tctggttatt tcgttccttg
     1381 ctgatgtaaa tatccatgtc attatttcat tgttaggagt aaaacaaaaa ttaattgttt
     1441 ctgaacgaaa tgatccacaa cggaatccag aagaaccatg gattaggaaa attagagatt
     1501 ttctttataa aaatgtagat ggaattgttt ttcaaacacc agacgcaaaa aaatatttta
     1561 gtaagatcaa tgataaaaaa gtaaaaac
//
LOCUS       DAFLVO010000196         1531 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.202, whole genome shotgun sequence.
ACCESSION   DAFLVO010000196 DAFLVO010000000
VERSION     DAFLVO010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1531
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.202"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            17..1483
                     /locus_tag="L1U99_003041"
     CDS             17..1483
                     /locus_tag="L1U99_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBN1213531.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          419 a          289 c          325 g          498 t
ORIGIN      
        1 aattggggta tagattatgg aaaaacagca agacaagggc ttcttcgggc agccgaaggg
       61 attgtcaact ttgttcttca ctgagatgtg ggaacgattt agttattacg gtatgcgtgc
      121 attacttatc tattatatgt acgatacagt tgccaacggg ggacttggat taccacgagc
      181 aacagcatta gctatcatgt cgatctacgg atctttgatc tacatgtcta gtatcgtcgg
      241 cggatgggta tctgaccgag tgttaggagc aaaacgcact gtattcttcg gtggagtttt
      301 cattatgctt ggccacatcg tcttggcttt accatttggt gtaagtacat tgtttgtttc
      361 gatggcattg attattatcg gaaccgcctt tttgaaacca aatgtttctg gcatggtcgg
      421 acatctttat tcaaagactg acttgcgaag agatgcagga ttttcgattt tttacatggg
      481 tgtcaactta ggggcattat tagcaccact aatcgttggt acaatcggtc aagaatataa
      541 ctatcattta gggttctctt tagctgctat tgggatgttc tttggattat tacaatacat
      601 catccaagga cgcaagacat tagacggagt gggtacaaca ccgccgaatc ctttgacaac
      661 tgaagaacgt aaaggattca tccgtaactt gatcatcgca cttgttgtta tcgctgcagt
      721 attcggcggg gcacaactaa ctggtcatct gacaattgac ttttttgtca atacaatcag
      781 tgtattgggg attatcttac cgttgtatta ctttatcaaa atgctgactt caaaagatgt
      841 aactgctgaa gaaaaaccaa gagtatgggc ttatatccca ttattccttg cagcaatcat
      901 tttctggtca ttacaagaac aaggttcatc tatcttagct ttatttgcta gtgaacgtac
      961 acaatctacg ctatttggtg taacgatcca agcaagctgg tatcaatcat tgaatccaat
     1021 tttcatcttt attctgacac cagtattcgt aacgatgtgg acgaaacttg gtgaacgtca
     1081 accatctaca gtagtgaaat tctctcttgg acttttattt gcaggattat cgtacttgct
     1141 attgatgttg ccgggtatgc tttatggtac aagtggaaaa gtaagtccat tgtggttgtt
     1201 gggaagtttc ttcatcgtgg ttattgctga attgtgtctt tcaccagttg gtttgtctgt
     1261 gacaacaaaa ttagcaccac gagcatttga atcacaaaca atcgctattt ggttcttagc
     1321 tgatgcttct tcacaagcaa tcaatgcaca aattgcacgc ttctacacac cgggaacaga
     1381 atctgcttac ttcggtatta tcggtgcagt agcaatcgtc ggtggtatct tgctatttac
     1441 tgtgaaagaa ccaatcaaaa aactaatggg ctctattcat taatcaatga acataaaaac
     1501 aggaattgct tatttgcagc agttcctgtt t
//
LOCUS       DAFLVO010000197         1483 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.203, whole genome shotgun sequence.
ACCESSION   DAFLVO010000197 DAFLVO010000000
VERSION     DAFLVO010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.203"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            64..972
                     /locus_tag="L1U99_003042"
     CDS             64..972
                     /locus_tag="L1U99_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBN1213532.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            972..>1483
                     /locus_tag="L1U99_003043"
     CDS             972..>1483
                     /locus_tag="L1U99_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213533.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGV"
BASE COUNT          511 a          216 c          345 g          411 t
ORIGIN      
        1 cagtattata gtgcaagtgc aatttcttcc attgtcatac caccaaaata gggaggtgat
       61 ttaatggcaa agtggaatgt catattaagt acaacagaac cctataatta cgtggggatg
      121 attcaagttc gacaaggcaa taagaataca gaggttatgg aagcgactat agttgaaaat
      181 ggtcttccct acgatttatc agaatgtaag gtatattttg aatcagttgt aggtgggaaa
      241 tatccagtcc aattagaaac aaaaattgtg gatgctaaaa aagggaaaat taactatatt
      301 tttgataaat attccatgca gtgtttacat cgacaaacag ccaatttcat tatatttaaa
      361 ggagaagact tgattggaac aactcaagac ttctcttatt ttgtcattaa tgctgtttca
      421 aaaacagaag gagaaatggg ttcttattgg caatcaatcg aagatttaat tgcggatatg
      481 acggacttta ttaatgaaaa taaaggcgat tttacggact ggatgaatga aaggaaagaa
      541 gaatttgaac gttggagaca agaacaggaa cacagtttcc aagattggag agaaggacaa
      601 gaatcagact atttggcatg gtttgaatca atcaaggata ttttaaagac gattgatcca
      661 ggtggagtca tgttagccga actaacggat gcgcgagtag atattcaagg agttcgtcat
      721 gcgtctattt cagagcgttt gctggcagat atggactatt tatatcagaa attgcgagca
      781 acgcttttca cgattgaata cggggagatt gaagtgactg atattttgca ggatgatctc
      841 ttttcagata atcatgaagt cgaaaaagtt ggaactgtag cattcccgat tgaagaagga
      901 gccttgatca tcgcaaccgt tgatgatcca aagcaaaatg tgttcactct tgagaaagtt
      961 ggggtgatct aatggctaaa actaaacgaa tgatggaaac ggatgaaaaa acgggtgtac
     1021 aacgccaatt ctttccaatc acacatgctt ccgcagttct tgggttagaa gaaataatag
     1081 caggagaagc aacagtttta tctgttaatg gaaaaattgg agccgtcgtc attactaaag
     1141 aagatttggg attagagaat gttctcacag aattacccta tgcaagtgaa gaagatgacg
     1201 gcattatcac ggcagaaatg tatcaaaaaa ttttaaacag tggagaaggt gactacgtgt
     1261 tgccagttgc cactatcgac cgtttgggtg gcataaaagt tggtgaatta ttgacgattg
     1321 atgagacagg gaaagtctct gcagtcagac aatctgatgt caatttttcg ctggagttaa
     1381 aagaaaaact cgattcactg aaaaattata ctgctggaga aaacatcact attgatgaag
     1441 atggaacaat tagttctaca ggtggtagtg ggactggtgg tgt
//
LOCUS       DAFLVO010000198         1480 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.204, whole genome shotgun sequence.
ACCESSION   DAFLVO010000198 DAFLVO010000000
VERSION     DAFLVO010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.204"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            64..972
                     /locus_tag="L1U99_003044"
     CDS             64..972
                     /locus_tag="L1U99_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBN1213534.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIETVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            972..>1480
                     /locus_tag="L1U99_003045"
     CDS             972..>1480
                     /locus_tag="L1U99_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213535.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGV"
BASE COUNT          529 a          197 c          316 g          438 t
ORIGIN      
        1 cagtattata gtgcaagtgc aatttcttcc attgtcatac caccaaaata gggaggtgat
       61 ttaatggcaa agtggaatgt catattaagt acaacagaac cctataatta cgtggggatg
      121 attcaagttc gacaaggcaa taaaaacact gaagttatgg aagctacaat tgtcgaaaat
      181 ggtcttccat atgatttatc agaatgtaag gtatattttg aatcagttgt tggcggaaaa
      241 tatccagtcc aattagaaac aaaaattgtg gatgctaaaa aagggaaaat caaatatatt
      301 tttgataaat attccatgca gtgtttgcat cgacaaacag ccaatttcat tatatttaaa
      361 ggagaagact tgattggaac aactcaagac ttctcttatt ttgtcatcaa tgctgtttca
      421 aaaacagaag gagaaatggg ttcttattgg caatcaattg aagatttaat tgctgatatg
      481 acagatttta ttaatgaaaa taaaggcgat tttacggact ggatgaatga aaggaaagaa
      541 gaatttgatc gctggagaga ggaacaggag aatagtttcc aagattggag agaaggacaa
      601 gaatcagatt acttgtcatg gtttgaatca atcaaggata ttttgaagtc tatcgatcca
      661 ggtggagtaa tgttagccga attaatggat gcacgtgtag atcttcaagg tgtacgccat
      721 gaatcgattt ctgaacgttt cctatccgat ctaaattatt tgtatcaaaa aatgaaagca
      781 gcacttttca cgattgaata cggtgaaatt gaagtgactg atattcttca agacgatctc
      841 ttttcagata atcacgaagt cgaaaaaatt gaaacagtag aatttccaat tgaagaagga
      901 gctttgatta ttgcaactgt tgatgatcca aaacagaatg ttttcactct tgagaaagtt
      961 ggggtgattt gatggttaaa gtaaagagaa tgatggaaac tgatgaatct ggtgttaaac
     1021 gtcaatttat gccaattaca catgtctctg cagttttagg cttagaaaaa atgatatcag
     1081 gacaatcaaa agttctttcg gttaatggta aatatggtgc agtcatttta acgaaagctg
     1141 atttaggatt agagaatgca attactgaac taccttatgc aagcgagaca agcgatggta
     1201 ttcttactgc tgaaatgttt caaaagatcg taaatggaga aggtggaaca tatattttgc
     1261 cgattgctac tcctgaacaa ttaggaggta taaaagttgg ggaactctta gaagttactg
     1321 aagaaggtgt tttatctgca actaagcaaa cagacttcaa tttctctgaa gaattaaaag
     1381 gaaaattaga atctctaaaa atattaaaag caggtgcaaa tatatcaatt gcagaagatg
     1441 gaacaattag ttctacaggt ggtagtggga ctggtggtgt
//
LOCUS       DAFLVO010000199         1460 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.205, whole genome shotgun sequence.
ACCESSION   DAFLVO010000199 DAFLVO010000000
VERSION     DAFLVO010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.205"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            75..485
                     /gene="spx"
                     /locus_tag="L1U99_003046"
     CDS             75..485
                     /gene="spx"
                     /locus_tag="L1U99_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBN1213536.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            499..855
                     /locus_tag="L1U99_003047"
     CDS             499..855
                     /locus_tag="L1U99_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HBN1213537.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT          538 a          210 c          271 g          441 t
ORIGIN      
        1 ttttattagc taataattgg tattttaaaa gaaattactg tagaattgga ttataattaa
       61 aaaggagtga gaaaatgata aaagtatata cttcgcctag ctgtacttcc tgtagaaaag
      121 caagagcatg gttgcaagcg aatcaacttg aatttgaaga gaagaatatt tttgccgaac
      181 cgttaacaga aagtgagatc aaaaagatct tggcagcgac tgaaggagga gttcaagata
      241 ttatttccac tcggtcgaaa atttacgaaa agctgggcat agattttaac gaattaactt
      301 taaagcaaat gatcgtctta ttcaaagaat atccttcatt attgagacga cctattttga
      361 ttgatgaaaa aagaatacta atcggattta atgaagatga gatccggtca tttgtccctc
      421 gtgaaattcg atgtgttgcc agaaatctga tctatttaca aaacaataac atcttaaatt
      481 catagggagg gagccttcgt ggaagtgaaa gtctatggat cagcgcactg tgtaacaagt
      541 ctgaaggcga aacaatggtt agaacaccat caattgcctt atcaatttgt tgacttagaa
      601 gaacgcgatt taagtacaga agaagcagaa gaattatgca gttttgaaga agtgcaagca
      661 gaacagctat ttgcgacttg gtctgaggct tttcacaaca ttgcgattga cctttcctgt
      721 gtaggaaaaa aacaactgat ttttttatgc acacaacata ccaatctcct cagacgtcct
      781 ttgattatta tcgatgaagt tctatttatt ggatacaatg agcagttgat ggaacagctt
      841 atcttaaata aatagacttt aactgtttta atcaagtcac tgagcatttc atacagttgt
      901 aacagtcgaa cacttagcat caagcgtgtt atgtgttctt tttttgactt tatttttcta
      961 ctatagagac atgctcaatt tatgtggtca aaattcaaat ctaggtgggg atatagagtt
     1021 aaaaatatat tgacatgtgt aaatttacat gatatattca tttctgttgt tttaagtagc
     1081 aaagcaataa aatagtattt taaaaaacat ataaaatagt tgttgacatg ttagaaatga
     1141 catgataaga taactgagtt gttaaaaaag aaccacttgt gaagcttgat tctatcgaaa
     1201 aaaacttcaa aaaagttctt gacaaataac aaatgataag ttatgataaa tgagttgctg
     1261 taagatttcg aaaaacgaaa tcaaaaaaac ttttaaaaaa gagttgacaa ttacttgtct
     1321 ctctgatatg atataaaagt tgctacggca gccaaaaacg aatcggggaa cactcctgat
     1381 gaagtagacc tttgaaaact gaacaaagta agacaaacca aatgtgtagg gcgtcttgat
     1441 tcaattcaag acaacaaaca
//
LOCUS       DAFLVO010000200         1424 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.206, whole genome shotgun sequence.
ACCESSION   DAFLVO010000200 DAFLVO010000000
VERSION     DAFLVO010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.206"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(150..1337)
                     /locus_tag="L1U99_003048"
     CDS             complement(150..1337)
                     /locus_tag="L1U99_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HBN1213538.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DAFLVO010000201         1416 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.207, whole genome shotgun sequence.
ACCESSION   DAFLVO010000201 DAFLVO010000000
VERSION     DAFLVO010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.207"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            343..1146
                     /locus_tag="L1U99_003049"
     CDS             343..1146
                     /locus_tag="L1U99_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBN1213539.1"
                     /translation="MSQEVTEKIIDSDVDLVSEQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNLFRYLVKYDRREKDSFYSVLKDLSDKLGNLTYRFE
                     DSDVYEQLWLFQKFRIDKQKETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFETFDYEKIYAKKGRRVDRLRFTFSEPESNLPTISMHNWLEED"
BASE COUNT          534 a          176 c          286 g          420 t
ORIGIN      
        1 taggggaggc ttaatctctt gggagagtaa gtattaaagg ggtataaagg taacactttt
       61 ggacagtaaa ggtaacaaaa gtggacagta agggtaacag ttttggacag caaaggtaac
      121 aaaagtggac atttgaggta tcacactagg ataagacgtt accttcggtt ttcttgattt
      181 ggaaggcgaa aaaatagaaa attagattag taacaaatct ttgttgactg ttacctttag
      241 ttgtgattta atttaggtaa caagcagaaa aaattgtttc ctttaattag taccagatta
      301 acatgattaa aggagcgcaa aaagaagatt ggagagtaat caatgtctca agaagttacc
      361 gaaaagatta ttgatagtga tgtagattta gtatcagaac aaacaaatgc aattgtgcgt
      421 tataacaatg gtctgaatac aacagctttg cgaggattta agcctgttga aatggatgtg
      481 ttttgggcta ttttatcaaa aatgaaacgt caaggaacag cagaagtaac ttttgatttc
      541 aacctctttc gttatttggt caaatacgac agaagagaaa aggacagttt ttattctgtg
      601 ttaaaagatt tgagtgacaa actaggtaat ttaacctacc gttttgaaga ttcagacgtc
      661 tatgaacagc tgtggctttt tcaaaaattc cggatagata aacagaagga aacagttaca
      721 attaaggcaa atgaggaatt tgaatttatc ttaaactcaa ttggcaaaaa ctttactcgt
      781 tttgaacttg ataattttac aaaactaaga agtagctaca caaaagaatt gtatcgtcat
      841 ctcatgcaat acagaaataa agagtggcga aatggttatt gggtagtcaa agttgaagat
      901 tttagaagag cattaagtat accttcaagt tatagaatga caaatattga taaaagaata
      961 ctagagcagg cgaaagaaga atttttagct cctgatgaaa acggaataca ggtatttgaa
     1021 acttttgatt atgaaaaaat ctatgcaaag aaaggaagaa gagttgatcg gctcagattc
     1081 acttttagtg agccagaatc aaacttgcca accatttcaa tgcataattg gttagaagaa
     1141 gattgagaag aagcaggttg taattttaat acaacctgct tctttaaaaa agtatgggta
     1201 acacttttgg acaataaatg caagaagttt ttttgtaagc aagtttcagt ctaaataata
     1261 tttgaaagaa tggctaatct atacaaattt taacaactat gggtaacact tttggacaag
     1321 tcaagaaaaa aaacaatttt tcttaatttg ttgatcgact aaaggtaaca cttttggaca
     1381 acacagaata aaaagtccgg tgatatcagt tttggt
//
LOCUS       DAFLVO010000202         1365 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.208, whole genome shotgun sequence.
ACCESSION   DAFLVO010000202 DAFLVO010000000
VERSION     DAFLVO010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1365
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.208"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(60..278)
                     /locus_tag="L1U99_003050"
                     /pseudo
     CDS             complement(60..278)
                     /locus_tag="L1U99_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(544..738)
                     /locus_tag="L1U99_003051"
     CDS             complement(544..738)
                     /locus_tag="L1U99_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213540.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(838..924)
                     /locus_tag="L1U99_003052"
                     /pseudo
     CDS             complement(838..924)
                     /locus_tag="L1U99_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT          487 a          221 c          182 g          475 t
ORIGIN      
        1 ggtattttta ttatatatag atttaacata tgtcggtcgg ttgattgata tagctaaagt
       61 tataactcaa ccgaagccga ttcatctaca cgaataaagt tgcgagtgtt ctcggctaat
      121 tcataaaaat tgttatgtgt tccatatagc aatactggaa taactttatt ttcttgaatc
      181 tcataagcaa ctctatacac ggtgaccgca tacttaaatc cattagacca attacctgat
      241 aaacctccag ttttttgctc ttacttaaat ggatcaatgg caatttcatc acaaacctat
      301 agaggatgag tgacttctgc ctaattacgt taaaaaatat tgaaagtaac tctatgtagc
      361 aaaaaatatc tagaatttca tttcctcaaa actgatcgat attgtatcta aaaatatata
      421 ctacctaaaa taggtagtat atattaaaat atgtgctttt gttagaaaaa tcaatacata
      481 aattatcata tctgtatatg tcatttaggt atttcagtta tgttataata gttttgctgt
      541 ctgctacccc ggcctaatct ggcaagggga ggaggagata taatgaaata cctttttgat
      601 tttgtttttg caatcaagcc acttgcagat gtagtgtgca gttacctctg caaatggctt
      661 gattgcaaaa ttgccaaaaa agacagtaag cctacccgtt aattctataa tatagaaacg
      721 taaaaaaaac cccatcagcc tgcacgctga tggggtttgg tgatataatg aaatacctct
      781 ttgttactca taattatacc ataattagtc acgaatgcaa ccaatagaaa aaactactta
      841 gaacggtaga tcatcgctaa taacaatgca ttgtccacca aatggatttt gtgaagcatt
      901 aaatacattg ttattaattg tcgctgcttt taactaggcc tctccccttc tattataaaa
      961 gaagatatat atcatttctt aattacctac taccttaaac caaaatttaa gtactaccta
     1021 atttaagtag tacttaaaca atctaaaaaa tagttatccc aattgttatg cttttataat
     1081 acgattattt gtaacaaaat gaatattata taattaaaca ctaccatatt taggtagtgt
     1141 ttaattatta gcaaaacaaa aaatatttat tctattctct taacttcaac taagttatgc
     1201 tgcacacctt tatataaatc atatgcaact cattagctag acaaactaca agcatgtagt
     1261 tttatctgtt aattatgtac tacctaaata aagtagttta taattagcaa gtatatatat
     1321 ttaaaaattt aagattaatt tttttatgac ttgtacaaat ttatc
//
LOCUS       DAFLVO010000203         1364 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.209, whole genome shotgun sequence.
ACCESSION   DAFLVO010000203 DAFLVO010000000
VERSION     DAFLVO010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.209"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            82..>1364
                     /locus_tag="L1U99_003053"
     CDS             82..>1364
                     /locus_tag="L1U99_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HBN1213541.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQL"
BASE COUNT          465 a          262 c          257 g          380 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taat
//
LOCUS       DAFLVO010000204         1364 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.210, whole genome shotgun sequence.
ACCESSION   DAFLVO010000204 DAFLVO010000000
VERSION     DAFLVO010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.210"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(140..1288)
                     /locus_tag="L1U99_003054"
     CDS             complement(140..1288)
                     /locus_tag="L1U99_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1213542.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
BASE COUNT          393 a          242 c          216 g          513 t
ORIGIN      
        1 taaacctgac ggttcttaac gcttgaagtg ggagcttctt gggaatagag catacttgat
       61 agcgtatttc tttactaaca gcggtgtctc ttatttacca agctatcccc gtagttccta
      121 cggttcttga tgattggatc taagccaatc ccatagaatg tagtcttaga ccttcggtca
      181 gaatattgat actagcattg atatcacgat catgatgagt atgacaaaca ggacaagtcc
      241 attctcgaat ttcaagagat ttcttgccat ctttatgtcc gcactctgaa caaatctgac
      301 tagacggaaa ccatttatct actttgatga tttttcgtcc ataccagtca gccttgtatt
      361 gtaatttagt cacaaacttt gaccaagaaa catcagaaat acttttagct aatttatgat
      421 ttcgcaacat accttttgtg tttaagtctt caatacagat aatatcgtga tttttgatca
      481 tttctgtact caacttattc agaaaatcag tacgttgatt cattactttt tcatgcaatc
      541 tagctacttt gcgtttttgt ttttgataat ttttagcttc aaatagattg gtacctttat
      601 ttttagccaa taaagcacgc ctagacaatt tgcgttgttc acgctttagt ttcttttcca
      661 ttttggacgt gaatttatta ttatcaattt tttgtccatc agaaagaatc gcaaagtcca
      721 taatacctaa gtcaatacca attgtggaat tagttttagg taattcgata atttcttctt
      781 tacacaacaa agaaatatag tatttaccgc tagaatgacg tgatattgta gcagatttga
      841 taatcccttt tggttgtcta tgaagcttaa ttcttactaa tgacttcaat ttaggaactt
      901 tgatgaattt actatcaatc aaagcaactg taccattttg attattcgtt gtataactct
      961 gaacaggatt tttcttactt ttgaaacgtg gaaatccaac ggatttatcc cgaaaaaaat
     1021 tcttgtatgc tttatctaaa ttaagttggg cattggctaa agcaaggcta tcaatttctt
     1081 tcaaaaacgg aaattctttc ttgtatttag ctggtgtcgg aaaagtcatt tttttagaag
     1141 aatcattttt aacttcttca tacgcctttt ttcggtcatc aagcattaga ttgtagacct
     1201 tacggacaca accaaaagat ttggcaaaga agatttcttg ttcctctgtt ggatagattc
     1261 tgaatttgta tgcttttagt tgttccataa agttcaccta ctttctattt atgattgttt
     1321 ccttgatttt ggatatactt cttaatcaca tcaattggtg cgcc
//
LOCUS       DAFLVO010000205         1355 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.211, whole genome shotgun sequence.
ACCESSION   DAFLVO010000205 DAFLVO010000000
VERSION     DAFLVO010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.211"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..1355
                     /locus_tag="L1U99_003055"
     rRNA            <1..1355
                     /locus_tag="L1U99_003055"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          362 a          295 c          415 g          283 t
ORIGIN      
        1 caagctgtga tggggaggga aataatagta ccgaagttcc tgatgtcaca ctgccgagaa
       61 aagcttctag tgagaaaaca gcggcccgta ccgcaaaccg acacaggtag tcgaggagag
      121 aatcctaagg tgagcgagag aactctcgtt aaggaactcg gcaaaatgac cccgtaactt
      181 cgggagaagg ggtgctgatc atacgatcag ccgcagtgaa taggcccaag cgactgttta
      241 tcaaaaacac aggtctctgc aaaatcgtaa gatgaagtat aggggctgac gcctgcccgg
      301 tgctggaagg ttaagaggag tgcttagcgc aagcgaaggt acgaattgaa gccccagtaa
      361 acggcggccg taactataac ggtcctaagg tagcgaaatt ccttgtcggg taagttccga
      421 cccgcacgaa aggcgtaacg atttgggcac tgtctcaacg agagactcgg tgaaatttta
      481 gtacctgtga agatgcaggt tacccgcgac aggacggaaa gaccccatgg agctttactg
      541 tagtttgata ttgagtgtct gtaccgcatg tacaggatag gtaggagccg tagaaatcgg
      601 aacgctagtt tcgatggagg cgctggtggg atactacccc tgcgttatgg ccactctaac
      661 ccgcaccact aatcgtggtg ggagacagtg tcagatgggc agtttgactg gggcggtcgc
      721 ctcctaaaag gtaacggagg cgcccaaagg ttccctcaga atggttggaa atcattcgaa
      781 gagtgtaaag gcagaaggga gcttgactgc gagaccaaca agtcgagcag ggacgaaagt
      841 cgggcttagt gatccggtgg ttccgcatgg aagggccatc gctcaacgga taaaagctac
      901 cctggggata acaggcttat ctcccccaag agtccacatc gacggggagg tttggcacct
      961 cgatgtcggc tcgtcgcatc ctggggctgt agtcggtccc aagggttggg ctgttcgccc
     1021 attaaagcgg cacgcgagct gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc
     1081 gcgggcgttg gaaatttgag aggagctgtc cttagtacga gaggaccggg atggacttac
     1141 cgctggtgta ccagttgttc tgccaagggc attgctgggt agctatgtag ggaagggata
     1201 aacgctgaaa gcatctaagt gtgaagccca cctcaagatg agatttccca tttctttaag
     1261 aaagtaagat ccctgagaga tgatcaggta gataggtcag gagtggaagt acagtgatgt
     1321 atggagcgga ctgatactaa tcgatcgagg actta
//
LOCUS       DAFLVO010000206         1336 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.212, whole genome shotgun sequence.
ACCESSION   DAFLVO010000206 DAFLVO010000000
VERSION     DAFLVO010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1336
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.212"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            181..600
                     /locus_tag="L1U99_003056"
                     /pseudo
     CDS             181..600
                     /locus_tag="L1U99_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352869.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            737..>1336
                     /locus_tag="L1U99_003057"
     CDS             737..>1336
                     /locus_tag="L1U99_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213543.1"
                     /translation="MSEDLRELKLRKKQYDQYFSGLLNKHIEEGLDHDFGKDEYCLYC
                     ERYNEKMSEYLQLKKEIQKLEKKVHAWKYKDSMSGYVESQNKPRKKKQAYVLKMVNGE
                     ELIVLAYSEEEVRELVETPVRKKVETINEIDDSQYNSIYIETSHGGYKKLATFLRSSK
                     VGIISKKDISAVTDSFCTLSVPKAYFQYDSKRFERLEKFC"
BASE COUNT          509 a          171 c          272 g          384 t
ORIGIN      
        1 gatgccatta tggtcaacat ttttggactg gggaagtcag agaaaatata gatcgtgaat
       61 atgttcaaag aattgtttgg gatgcatatt ctatcaaaga ttatcctaaa agtttaacga
      121 gtagattatt ttacagtgaa aaagataatc aaaaactctc agatttgatg atgaaaaaag
      181 tatgactatt attacgaaag agaaacagag tgctatattc gaggggaaaa agcctacaac
      241 aaaagtgact attggggtga caaggcgaag cgattaactg caaattttag agtgtatgaa
      301 tcagagttta taaacttgac ctttcttaat agtgttttta ttgattatgt aattactacg
      361 aaacgcattg gaagttattc aagtacctac gcatccttag ttccaatgtt aaactcgatg
      421 agccgtttct taaaagaaag agaaaagaaa gagctacagt atatcaaaga aatcatgccg
      481 gattttgaaa tgcacgaatg gcaaattgct ttatcagatt ggaaattggc gaataaggtt
      541 cgtagaataa caccttttca agccaagcgc tttttgagag ctatgaaatt tgtgcaataa
      601 aaaaagccac cagacaagtt gatggagact aacacaatta ccaacagttg taattgtgtt
      661 agcttacaaa ttaattatgg tgtttagtca atcccaaatt gtgaaatggc accaataatt
      721 ggaaaggaaa aatgaaatgt ctgaagattt acgagagctg aagttacgaa agaagcagta
      781 tgatcagtat ttttccggtt tgttgaataa acatattgaa gaaggacttg atcatgattt
      841 tggaaaagat gaatattgtt tatattgcga acgttacaat gaaaaaatgt ctgaatatct
      901 acagctgaaa aaagagatac agaaattaga gaaaaaagta catgcttgga agtataaaga
      961 ttccatgtct ggttatgttg aatctcaaaa taagccaaga aaaaagaagc aagcgtatgt
     1021 tctaaagatg gtaaatgggg aagagttaat tgtattagcg tacagtgaag aagaggttcg
     1081 agaactcgtt gaaacacctg tcaggaaaaa ggttgaaaca ataaatgaga tagacgacag
     1141 ccaatacaat agcatctata ttgaaacaag tcatggtgga tataagaaat tagcaacttt
     1201 ccttagaagt tctaaagttg ggataatttc taaaaaagac ataagtgctg ttaccgatag
     1261 tttttgtact ttatctgttc ctaaagctta tttccaatac gatagtaaaa gatttgaacg
     1321 cttagagaaa ttctgt
//
LOCUS       DAFLVO010000207         1331 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.213, whole genome shotgun sequence.
ACCESSION   DAFLVO010000207 DAFLVO010000000
VERSION     DAFLVO010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1331
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.213"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            122..>1331
                     /locus_tag="L1U99_003058"
     CDS             122..>1331
                     /locus_tag="L1U99_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBN1213544.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVL"
BASE COUNT          415 a          261 c          255 g          400 t
ORIGIN      
        1 gctctatact ttttgatgtt ggtgaacttc accaacatct tttttgtata aaaaaatata
       61 gaaaagacac cctgaaatcc tttagaatta atttggctac caattcatag gaggattcaa
      121 gatgtctcat actcagctta tcaaagatac cctaaatatt ctagacctaa atatctattt
      181 cgaggaaaat tgtttaacta aagaaaaata caaagggcaa atttgcttga tttacaaagg
      241 aactcttctg tacaagccag aagagtgttc ccattgtctt tgtgtcgtcc cctctaggat
      301 cattcgttgg gggacgacaa ccgttcggtt gttactgaat gatgtgtctg agtatcgcac
      361 ttatctggag ctgaagaaac aacgatttaa atgtaagtct tgccaaagaa cattcgtagc
      421 ggatacctct gttgctgaaa aacactgttt cattagtcaa aaagttcgtt ggtctgtcat
      481 tgctcgctta aaagagaata cttccatgac ggaaatcgct cgtcagaaaa atatttccac
      541 ttcttcggtc tatcgtgtca tgaagcgatt ctaccgccca ttgaatcctt tcaaacagac
      601 tttgccaaag gtcttatgct ttgatgaatt caaatcggtt cgaagtgttg ccagtgcaat
      661 gagttttatc atgatggacg gacaaagcca tgcattattg gatattgtcg aaaatcgacg
      721 cttgccttat ttagaacgct atttttctcg gttttcatta gcgactcgtg aagccgttca
      781 attgattgtt attgatatgt atgcgcctta tgtttcgttg gtgaaaaagc ttttcccgaa
      841 tgctcagttg atcatcgatc gtttccacat cgtccaacat attggcagaa ctttcttgaa
      901 tcatcgagtg aaagaaacca cggtacgact taaaggaaat tcccactctc aacgagggtt
      961 agggaaaaaa ttgaagcgct attggaaact cctacaaaaa gaagaagcaa agttaaacta
     1021 tgaaaaacgg gtttggcgtg ccagttttaa agattatttg actgaaagtg agattgccga
     1081 tcgactgtta gctgcttgtc ccaacttacg ccaaggctat cagttatacc aagacattct
     1141 ttatgcggta aagaaaagag atcagtcact atttgaggat tgtttaacta gagacattag
     1201 cggtctgcca gaaacctata caaccacttt acgaacgttt aaaaagtttc tgccacagat
     1261 ccaaaatgcg cttcactaca gctattcaaa cggaccattg gaatgcttaa acaaccacat
     1321 caaagtatta a
//
LOCUS       DAFLVO010000208         1328 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.214, whole genome shotgun sequence.
ACCESSION   DAFLVO010000208 DAFLVO010000000
VERSION     DAFLVO010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1328
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.214"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            33..>1328
                     /locus_tag="L1U99_003059"
     CDS             join(33..474,474..>1328)
                     /locus_tag="L1U99_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HBN1213545.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKL"
BASE COUNT          559 a          169 c          231 g          369 t
ORIGIN      
        1 gactagaaat ctaattaaaa ggggtgcttt ttttgcggaa atatacattt gtttttaaga
       61 aaaaagtagt ttcagactat ttaaataacg aaggcggcta caaatatctt gcacataaat
      121 atcaaataaa tcgtacactg gttagacatt gggtaaggat ttataactat catggttggg
      181 aaggcttggt tggaggtggc aaaagctaca ctacaaaatt taaacttgat gttatagaat
      241 atatggaaac aaatggtctt tctatccaag aaactgctaa aaaatttaat atcggttcaa
      301 atagaactct aagtaaatgg atagagcaat atgaagaagg cggtgcttct tcacttgaga
      361 gccaaaaaag gggcagaaaa attagtatga attccaagct aaacattcct aaaaaactta
      421 aagatgagtc tcttgaagaa gaagttattc gtttaagagc agagaacgca tatttaaaaa
      481 agttagaaac cttgattcaa gaacaagatt tgagcaagaa gaaatcaagg ttaaaacaat
      541 ccttcagctc aaaaaagaat ttaaattgaa tctattactt tcaattgcac aattagcgaa
      601 gtcaacttat tattactggg taaaaaaatt agataagcca gataaatata gcaagataaa
      661 gcaagaaatt acagcgattg taaaagaatc aagaaactct tatggttatc gtagagtcac
      721 tttagcgtta aagatgaaag gatatacaat caatcataaa acagttagaa aattaatgtc
      781 ccaaatggga cttacctgtc aaatccgaat aaagcgatat aaatcttata aaggaacagt
      841 aggaaaaatt gccaagaatg tgttaaaacg aaatttttca gtagatacac ccaataaaaa
      901 atgggtgaca gacgtcactg aattcaagat aaaaggaaga aaaatctatc tatctcctat
      961 acttgattta tttaacggag aaataattag ttatagtata tcaactagtc caacatataa
     1021 actgattgaa gaaatgcttc aacaagcaat taaaaaaaag ggaactgagg gttcactgat
     1081 tctacattca gatcaaggat ggcagtatca gatgccacaa tatcaaaaaa aattaaaaga
     1141 gaataacatt attcaaagca tgtctagaaa aggaaattgc ttagataatt ctgtaataga
     1201 aaattttttt ggtgtgctta aatcagagtt tttttatcga gaaaaattcc gatcaattga
     1261 gatatttcaa agtaaattaa atgagtatat taggtggtat aataacaaaa ggataaaact
     1321 aaagttaa
//
LOCUS       DAFLVO010000209         1328 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.215, whole genome shotgun sequence.
ACCESSION   DAFLVO010000209 DAFLVO010000000
VERSION     DAFLVO010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1328
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.215"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(55..978)
                     /locus_tag="L1U99_003060"
     CDS             complement(55..978)
                     /locus_tag="L1U99_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213546.1"
                     /translation="MATNYAKKINFDVDKLYKSLIVVPKNKSEDGNYELEVLQFKIEQ
                     KSSERFMSNQLVKIKKWLPMIDQLVSNNKEAKNLCIFVLLLHGRVINLVNRKSTTKFA
                     NSFWFLKNINKTVEKNGVYKGDFHFQNAETIEREHHYFDLLVNTVVELAKWAKSNETY
                     SQVLKRIMSQETSFIYELSKSNLKYTYNEDELEILDNPENSQWIKELKREDFIETLRI
                     LKSLFDLKLAKATIMGIERDSYYWEEIGLYAPQIEGEDKEKRIDNIINYINSLSEPLK
                     CRGLDFIGTLGWTETYYEKIYKEIIEQYFPK"
BASE COUNT          429 a          234 c          133 g          532 t
ORIGIN      
        1 gtgattttgg aaatcacaac ttttttcttt tacgataaat caatccttat taaattattt
       61 aggaaaatat tgttcaatta tttctttata tattttctca tagtatgttt ctgtccatcc
      121 taatgttcct ataaaatcaa gtcctctaca ttttaaaggt tcacttaaac tattaatata
      181 gttaataatg ttgtctatcc ttttctcttt atcttcacct tcaatctggg gagcatatag
      241 tccaatttcc tcccaataat atgaatctct ttcaattccc atgatggtag ctttggctaa
      301 tttcaaatca aataacgatt ttagaattct tagtgtctca ataaagtctt ctctcttcaa
      361 ctctttaatc cattgtgaat tttctggatt atctaaaatt tcaagttcat cttcattata
      421 agtatatttc aaatttgact tgcttaactc atagataaat gaagtttctt gactcataat
      481 tcttttaagt acttgactat aagtttcgtt tgactttgcc catttcgcta attctaccac
      541 tgtattcact aataaatcga aataatgatg ttctcgttca atagtctcag cattttgaaa
      601 atgaaaatca cctttataaa ctccattctt ttccactgtt ttattaatat tttttaaaaa
      661 ccagaatgag tttgcaaatt tagtcgtact ttttcgatta actaagttaa taactcttcc
      721 atgtaataat aagacaaaaa tacataaatt tttagcttcc ttattattag atactaattg
      781 atcaatcata gggagccatt ttttgatttt cactaattga ttgctcataa atctttcact
      841 ggacttttgt tcaatcttaa attgcaaaac ttctaactca taattcccat cttctgattt
      901 atttttggga acaactatca aacttttata aagtttatcc acatcaaaat ttatcttttt
      961 tgcataattt gtagccatta atacatctcc ttattcataa taaatttcat atgacgctcc
     1021 tctcaaaatt taccggtaga ctagaaaaaa gaataaaaga tacgtcaatt cacactttat
     1081 tcttaaaaaa aaactggtct ctctaccggt aatatcgatt gagtccgcct ttatcgactt
     1141 tatccttttt ttatattaaa ttttttcacc ggtagacagg gagagaaaga ataaactaaa
     1201 aagcccttaa ttcttaatgt tttcacctcc ttaccgttcc taccgctaaa atttaatata
     1261 actaaattct ataacattag aagaaatttt aaataccttt gataaaaaat attgatgttt
     1321 tttctctc
//
LOCUS       DAFLVO010000210         1286 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.216, whole genome shotgun sequence.
ACCESSION   DAFLVO010000210 DAFLVO010000000
VERSION     DAFLVO010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1286
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.216"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(25..324)
                     /locus_tag="L1U99_003061"
     CDS             complement(25..324)
                     /locus_tag="L1U99_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213547.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(330..560)
                     /locus_tag="L1U99_003062"
     CDS             complement(330..560)
                     /locus_tag="L1U99_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213548.1"
                     /translation="MMEEFIRKNISDEYADFYEQSNEKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(810..1010)
                     /locus_tag="L1U99_003063"
     CDS             complement(810..1010)
                     /locus_tag="L1U99_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1213549.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT          444 a          212 c          194 g          436 t
ORIGIN      
        1 ggctaccttt ttaggtagcc tactttaatc tttgtatctt tctggatcaa cgaaagtata
       61 ctttatatag tcataacgcc gatgatcgct tcgagcgtct agcacatcag tcacgatatc
      121 aaacaaaaaa tatacgtctt tcttcattct agttttcgca gcagggattt taaagtagtt
      181 cttattagaa tagtagagat taattaataa gctatcttcg attgctaaaa agaaaacttc
      241 tgaatcccac accttataaa aatctttgac aaatctattc gaaggatcaa atttaaacca
      301 taattgcgtc tcattaaaaa gcataaccat tactccgatc tatttttaaa cttagtctct
      361 acctctaata tatatcgagt ttttattttg ccttcagaga atactgtttc tttttttgca
      421 gttacaggtt gtttattttc ggaaaaagct aatatagcta aaattgaaac atccatctgg
      481 aatttgtctt tttcgttgct ttgctcataa aaatctgcat attcatcact aatatttttt
      541 ctaataaatt cttccatcat aaagatcacc tcgaaaagag tatacgaaca aacgttcttt
      601 ttgtaaaggt ggaatttatt atactaaata aataggtgaa caagtacttg tgccaaatta
      661 tgtgccaaaa aaaatcgaat ttaataaaac acaaacaaaa agaaatccta ttatgataac
      721 atttcttata ataacaaaca caacagaaga cgtgtaatag ttagtcagga acgtacaaat
      781 aacccctgta tcctttgcgg tacagggggt tattttgtat aagtagacat tgtagtttct
      841 aaactgctat gtcctaaacg tttcgatacg ctaagtatat ttactccttg ataaagtaaa
      901 atagatgcat gcgtatgtct tagtccatca ataaacagtc gaagagaaaa tagggaaaaa
      961 ttgattacta aagaaaaact tactaggtcg acggtgtagt tgattttcat acttcaatag
     1021 attcgaatta aacgatttcg attggcttat accagtccta tccaacgaaa gatatatcgt
     1081 tcttaactct agcggtataa cttgaagctt tacgtaaagc caatgggaat gaactggaga
     1141 tgacttttta ttatttttag taatagctga tgggttaata cttacaactt tccttttcaa
     1201 agtaccatat aaaaaaacgg tggggttgtt tagcgaaata aaggatctaa gccaatagct
     1261 tagatccttt attctatgct ttatat
//
LOCUS       DAFLVO010000211         1279 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.217, whole genome shotgun sequence.
ACCESSION   DAFLVO010000211 DAFLVO010000000
VERSION     DAFLVO010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1279
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.217"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            282..521
                     /locus_tag="L1U99_003064"
     CDS             282..521
                     /locus_tag="L1U99_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213550.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(883..1143)
                     /locus_tag="L1U99_003065"
     CDS             complement(883..1143)
                     /locus_tag="L1U99_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213551.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
BASE COUNT          426 a          233 c          174 g          446 t
ORIGIN      
        1 tatcctccta gcaactattt aaatacccaa aaaaattacc tctagataat atcataccta
       61 cgttttcact tataaatttt ttcataaaaa aagcgtttag aggcataatc gttaatacag
      121 atggtaacca atgtatctgg tttgaactgg gatatcaccc tctccatata tgtattacta
      181 agactaatag atactataaa agacttgata gttttgcatt gattttgcct aatactgagc
      241 ataggtgtat gctaaacgat actataagga gtgtgtacat aatgaaaaga attctgttta
      301 tcagtttatc aaatttattg ttacttactg cttgtgggac ttctgcatca aagaacatac
      361 cttcagatac gcaaatttcg aatagtatcg attcaacaat ttctacaaat gagaaaaatt
      421 ctccggtaga aacttccgat ataaaagttt ctacctctgc aaaaaacagg gtaaagaaac
      481 tgtcagcacg tctcctttat ttcaaacaaa ctctgaatta gcttcttcat cttcttcagc
      541 aaataatgat gatagtttcg cgtttactcc taactaaatg caacctttac aaatgcttta
      601 cgataacaag cctgagctaa atgatcctga tatcagtttt gcattttttg aaatgattgg
      661 atcggatgat ctttttaaaa ctactagttt gtctatccga aaataggaca gttctggcag
      721 tataggtttt tatcgagttt ctccaccagg cctcgttaca gagacagatt ctctaggcga
      781 accttttgaa taaatcaaaa atcatgaaca atcactgcca actaaataaa gtgccttcaa
      841 aagcttggtc ttctcgcttt tgaaggcact ttatttaaat ctttatgaaa ctaaagtatg
      901 ttcatatttg ttgctatagt tatatagata ttctgttgtt tccaactcat aaacgtgagt
      961 atattttgcc actacttttc cgcatttttc taatatttca ttgcgatcga cgtcatgata
     1021 ttcgtctacg cagatcacaa cacaattttc taatttactg attacttctc caaccacttt
     1081 ttgtttcaag ccaataggtt ggcaaatata tttttttcct aaaatgatag tttcgttatt
     1141 catatttcat ccatccttaa tgtttttcca ttatttaaaa tgataatacc attaaaatat
     1201 gattatgaaa atcaataaca cttgtgattt tataaaaaaa taaaaaaacc gaaaaacaga
     1261 aatgcccact gtctttccg
//
LOCUS       DAFLVO010000212         1246 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.218, whole genome shotgun sequence.
ACCESSION   DAFLVO010000212 DAFLVO010000000
VERSION     DAFLVO010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.218"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            200..742
                     /locus_tag="L1U99_003066"
     CDS             200..742
                     /locus_tag="L1U99_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213552.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..>1246
                     /locus_tag="L1U99_003067"
     CDS             898..>1246
                     /locus_tag="L1U99_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBN1213553.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          514 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccag
//
LOCUS       DAFLVO010000213         1241 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.219, whole genome shotgun sequence.
ACCESSION   DAFLVO010000213 DAFLVO010000000
VERSION     DAFLVO010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1241
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.219"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            150..1190
                     /locus_tag="L1U99_003068"
     CDS             150..1190
                     /locus_tag="L1U99_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBN1213554.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
BASE COUNT          501 a          178 c          205 g          357 t
ORIGIN      
        1 agtacataat tcattttatt tctgatttta ggtagtattt aattaaaaaa cagttttaat
       61 gcgtttgcat tttttattta tctttgctat tttcgaaaag agtaggtaat tttacataaa
      121 taaaacaacg tgaaagtaga ggatctacaa tgactgattt taaatttttt aaggcggata
      181 gagtttacaa cgaattattt tatcaatttc caaaagtctt tattgtttct gacgaataca
      241 aaaaaatgaa agattcaact aagattgcct atatgctttt aaaagcaaga ttagagatcg
      301 caatcagcaa acggcaaatc gatgaagaag gtaatgttta ttttacttat acgacaaatg
      361 aactatgtag agtattaaac tgccaaaaac aaaaagcgat agcaatcaaa aaagagttgg
      421 aatcctttgg tttattatta caaaagcaga tgggatttaa caaacagtta gggaaaaata
      481 atcctaatag actatatcta gcagaattaa aagtctcaga aaatgatatc tacttactcg
      541 aaaaatttga tagagagaat agggaaaacg ttgataaatc agagggtatg aaaatcatac
      601 ccaccctcga cgaaaaatca gacgctgaat cccttggggc tcaagagggt atgaaaatca
      661 taccgtgcca aaacgttgat aaatcagagg gtatgaaaat cataccagaa cttaataata
      721 atatattaga cactaataga cacaatatag acactgaaaa agaccgccta caagatcaat
      781 tgttgttaga caattttgag acaattatga caaacgacag cattgctacg tttgtccctg
      841 aacgagtatt aaatttgata aaaacatttt cttcaagtta cagtgaagct caaaaaaccg
      901 tccagactat tcataatgca aagaaaaaag ctgaaataga aagtgatatt tcgatagttt
      961 ttgaagaact cgatagttat tatgtcaatg cagaacaaga attatacacg acactgttaa
     1021 aagcctatca aaaattaaaa accgaaaaag tcgaaaatat ccagaacctg atttttgtct
     1081 atgtaaaaaa ttggtttatc gaaaaaccaa tagctgctaa agtatcaagt gaaaaacgtt
     1141 tgaattatgc aagctcccca agcactatta cgaaagactg gttagagtga aactttactg
     1201 acaaagtgat tgttgcttca tggagtaaca ttaaaattaa a
//
LOCUS       DAFLVO010000214         1219 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.220, whole genome shotgun sequence.
ACCESSION   DAFLVO010000214 DAFLVO010000000
VERSION     DAFLVO010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.220"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..460
                     /locus_tag="L1U99_003069"
     CDS             <1..460
                     /locus_tag="L1U99_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBN1213555.1"
                     /translation="LLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTTLFVSV
                     IYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGLLPKFM
                     KVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            469..696
                     /locus_tag="L1U99_003070"
     CDS             469..696
                     /locus_tag="L1U99_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1213556.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT          377 a          195 c          204 g          443 t
ORIGIN      
        1 attgctatta aaatttgtcg ttttaggtat aagtgccgta tttattttgt tcggcgtact
       61 tttttatact cagatcgcta caagcgaaaa aggattcaat tttgattggc agaccacatt
      121 atttgtttct gtcatttact ttgcccttct cctagggatc gttattgctt atttcttatt
      181 gaaactattg aaaaaaatcg aagataacca agctttttcc actcaaagct taaacatact
      241 aaaaaaaatc gaacgaacca ttttgtttat tggtttcgcc ttttttggct tacttcctaa
      301 atttatgaaa gtagcggatt tagacgatgc tccaggtttg atgttggtag gaatcgctgt
      361 cgtattcatt ccttttgcag tatacacatt aacaagcgtg ctggaaaaac tgcttgaaca
      421 tgcgatttta cttaagacag atcatgattt gacagtgtga ggtgcgacat ggcaattatc
      481 gttaatttag atgtagtatt agctcaaaaa aaaatgagtg tgactgaatt gagtgagaaa
      541 gtgggcatta cgatggcaaa catctctatt ctaaaaaatg gaaaagcaaa agccatccgt
      601 ttttccactc tcgaaaaaat ctgccaagtt ttggagtgtc aaccaggtga tttgttgacc
      661 tataaaaatg actcgaatac tataccagaa gaataaaata aagtagaaca aacagtaaat
      721 aaaaaataat ctgaatgata gatgtgtgag acttttagaa gttatttacg tctattattc
      781 agatttttta tttcgattga ataccgtttt atctataaat aagatatgta ctgactcata
      841 caaagggggc cttttcttct ccatgtacta tcacttttcc tgatacaact ggtttcctgt
      901 tacgttgtag ttggatctgc ttttagtata atactttatt cattccacca gactgatagc
      961 agtttgagca gtctaaataa tcatgtagta ttacaggcca ttctgtttca taccttgaag
     1021 tgcttaaaac ttcagctaat ggcccattgt gttaactctt actccattct tttttagtaa
     1081 gctcccatat atactgtaaa gccttctata tattatgtca tgttgctttt taacatttac
     1141 tatgtagttt tgataaaatg atttgaataa cagtgatgga caattctttt ttatttttaa
     1201 cattattttg ataataatg
//
LOCUS       DAFLVO010000215         1195 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.221, whole genome shotgun sequence.
ACCESSION   DAFLVO010000215 DAFLVO010000000
VERSION     DAFLVO010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.221"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            56..331
                     /locus_tag="L1U99_003071"
     CDS             56..331
                     /locus_tag="L1U99_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213557.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            758..>1195
                     /locus_tag="L1U99_003072"
     CDS             758..>1195
                     /locus_tag="L1U99_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBN1213558.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEF"
BASE COUNT          451 a          205 c          181 g          358 t
ORIGIN      
        1 tataaccaaa ggcgctatga tttccatatg aaaaaaataa agtcaggtga aaaaaatgaa
       61 acttgaggat aaaaaagtca ttttgaagaa aatcaaacga ctaccagacc aaatagatgg
      121 ctatacgatc tgttctttca aaaaagacag gagtataaaa gcttatacgc aaaacacaga
      181 aaaaggaata atctatttcc tacatgaaga aggttacgat acccaaacct ttatgtttac
      241 tgaaaaaaaa gaatttcata aacagatgaa aaaactgatt gaaaaagaat ttccaagaag
      301 tcataaactc tatgtgaatc agcaatttta acttctaact gttctttatt aattaaaaat
      361 gttctgtaat aaaataaaac tttataacaa ctataacaaa accgaatgca aaacagaagt
      421 tctataagtt ataatcatag ttgttaggtg attcatctag taaaaacacc agatttcaaa
      481 tttcacacaa tttaaactag atcaatcatc aaccttcttc aaattgttag aaccctttcc
      541 cgaggagctg cagcataagc aaaaaaacaa acaggaagcc aaatggctaa gacatttttt
      601 ctattagtct agttgcttct cgtcgcaagt ttaagacttt agaaagttat ttctaatgat
      661 gtttgggttg ttttgatcaa tgcttatgca cagctcctta cctattattt atctcaacag
      721 atctaacaaa ttaatggact atttaaggag tttttttatg cttacgatct attcttctcg
      781 cacacatagt taccatctga tggcaaactg gctgaaagac catcaaatgc cttacagaga
      841 acgaattttc acacctaaac agcctttaac aaggaaagag atattttatt tattgtcatt
      901 aacagaaaac ggatttgacg atctattagc taaacgctcg attgattata aaaatttgaa
      961 agaccaaatc gaccaatgta cgacctcaga gcttgtcgat ctgatcgtct cgcattttac
     1021 tttgttacaa cgtcccatca ttactgacgg aaagaaatta ttagtcggat tcaatgaaga
     1081 tagcatgcgt ctttttatcc ctgtacaatg gcgcagaagt caactgaaat ctgtctataa
     1141 cgattttaca tgggtaagca atctagaaaa ttctacggat ttagatgatg aattt
//
LOCUS       DAFLVO010000216         1151 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.222, whole genome shotgun sequence.
ACCESSION   DAFLVO010000216 DAFLVO010000000
VERSION     DAFLVO010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1151
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.222"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..1138
                     /locus_tag="L1U99_003073"
     CDS             <1..1138
                     /locus_tag="L1U99_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBN1213559.1"
                     /translation="EIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQEYDKVILATGS
                     KQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYIGVEIAEAIRKR
                     GKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYLGRKKIEKIVTT
                     SGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKDIYAIGDCATTF
                     FTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFNYNFYAAGLNLK
                     TARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQLCSQEDLSGLLS
                     MFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
BASE COUNT          446 a          138 c          195 g          372 t
ORIGIN      
        1 tgagataaaa aagttatttc tagagacaga agttgacaaa attgatattc aaaataaaaa
       61 gattagttgt gtaaaaaaag atggtacaag attctctcaa gaatatgaca aagttatatt
      121 agctacaggt tcaaagcaaa ttatgctaga tataccgggg aataatttag ctaatatttt
      181 ttcgataaag aattttccaa atgcaaaaga gatttttaaa gctttggatg atagtactat
      241 taaaaaagta ggaattattg gagcaggata tattggagtt gaaattgctg aagccataag
      301 aaaaagaggg aaagaagtat atcttttcga tgttgcagat agagtgttgt cgacttatta
      361 cgaccgtagt ttttcagata aagttgaaga aatactatca aaaaatggaa tacatctttg
      421 tctatcagaa agtcctaaaa aatatttagg aagaaaaaag attgaaaaaa tagtcactac
      481 aagtggtacc caatactcta tggatatggt cgtacaagct ataggatttc tatctaatag
      541 tccaattggg gaaaaggaac tcttgagaga tgttagtgga gcatatctaa ctaatgaata
      601 ccagcaaaca aatataaaag atatatatgc tattggggat tgtgctacaa ctttttttac
      661 gtccattaat agaagtagtg ttgatttttc tatttctaat gctctaagaa cagcttatat
      721 tgcaactcaa catattaaca atcaagattt tacaccttct ggttcccaat ttacaaatgg
      781 cttttctata tttaattaca atttttacgc agcaggtttg aatttaaaaa cagcacgatt
      841 attaagtgag tctatagatt atatagaaat agaagatttc attagacctg cttttttgag
      901 aaaaaatagt cgtgtaaaat taagaattag ctttgaaaaa aatacaaaga gaatagtagg
      961 tgtacaactt tgtagtcaag aagatttatc tggactatta tcaatgtttt ctcttgctat
     1021 agaagaacaa attacattag acaaattgaa aatgttagat tatttatttc atcctagttt
     1081 tagccaaccc tataatttta ttttaaaggc agtaacagga ttaaacattg aaacataatc
     1141 gttactaaat g
//
LOCUS       DAFLVO010000217         1092 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.223, whole genome shotgun sequence.
ACCESSION   DAFLVO010000217 DAFLVO010000000
VERSION     DAFLVO010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1092
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.223"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(58..142)
                     /locus_tag="L1U99_003074"
     tRNA            complement(58..142)
                     /locus_tag="L1U99_003074"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(106..108),aa:Leu,seq:caa)
     gene            complement(163..233)
                     /locus_tag="L1U99_003075"
     tRNA            complement(163..233)
                     /locus_tag="L1U99_003075"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(199..201),aa:Cys,seq:gca)
     gene            complement(279..350)
                     /locus_tag="L1U99_003076"
     tRNA            complement(279..350)
                     /locus_tag="L1U99_003076"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(316..318),aa:Gln,seq:ttg)
     gene            complement(362..434)
                     /locus_tag="L1U99_003077"
     tRNA            complement(362..434)
                     /locus_tag="L1U99_003077"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(399..401),aa:His,seq:gtg)
     gene            complement(437..510)
                     /locus_tag="L1U99_003078"
     tRNA            complement(437..510)
                     /locus_tag="L1U99_003078"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(476..478),aa:Trp,seq:cca)
     gene            complement(517..597)
                     /locus_tag="L1U99_003079"
     tRNA            complement(517..597)
                     /locus_tag="L1U99_003079"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(561..563),aa:Tyr,seq:gta)
     gene            complement(599..674)
                     /locus_tag="L1U99_003080"
     tRNA            complement(599..674)
                     /locus_tag="L1U99_003080"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(639..641),aa:Phe,seq:gaa)
     gene            complement(710..782)
                     /locus_tag="L1U99_003081"
     tRNA            complement(710..782)
                     /locus_tag="L1U99_003081"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(747..749),aa:Asp,seq:gtc)
     gene            complement(792..864)
                     /locus_tag="L1U99_003082"
     tRNA            complement(792..864)
                     /locus_tag="L1U99_003082"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(829..831),aa:Val,seq:tac)
     gene            complement(880..951)
                     /locus_tag="L1U99_003083"
     tRNA            complement(880..951)
                     /locus_tag="L1U99_003083"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(916..918),aa:Glu,seq:ttc)
     gene            complement(966..1055)
                     /locus_tag="L1U99_003084"
     tRNA            complement(966..1055)
                     /locus_tag="L1U99_003084"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1019..1021),aa:Ser,seq:gga)
BASE COUNT          309 a          283 c          249 g          251 t
ORIGIN      
        1 ataaaagatg ttatttaatt tctcaataaa aaactaagat gaagacatct tagtcaatac
       61 cggcggccgg ggtcgaaccg gcacgccctc aacgggcact ggattttgag tccagcgcgt
      121 ctgccaattc cgccacgccg gcaagttgat ttattagtac taaggcggta accggatttg
      181 aaccggtgat gaaggttttg cagacctctg ccttaccact tggctatacc gccattatac
      241 tattatcaat ctataaaata aagaataaat tatagaaact ggggtagctg gattcgaacc
      301 aacgcatgag ggagtcaaag tcccttgcct taccgcttgg ctatacccca agaataaaaa
      361 gggcgaatga tgggaatcga acccacgaat gccggagcca caatccggtg cgttaaccac
      421 ttcgccacat tcgccatggc aggggcagca ggaattgaac ccacactaac ggttttggag
      481 accgctgttc tacctttaaa ctatgcccct ataaaatgga ggagagtgga ttcgaaccac
      541 tgaaccctaa ggaacggatt tacagtccgt cgcgtttagc cacttcgcta ctcctccatg
      601 gtggcgcggg acagaatcga actgccgaca cacggagctt caatccgttg ctctaccaac
      661 tgagctaccg cgccatattt taaaattatt aattgaataa caagaacgac ggttccgacg
      721 ggaatcgaac ccgcgatctc ctgcgtgaca ggcaggcatg ttaaccccta caccacggaa
      781 ccagttcatt atggaggtta acgggatcga accgctgacc ctctgcttgt aaggcagatg
      841 ctctcccagc tgagctaaac ctccaacatt caattaaaat gacccgtacg ggattcgaac
      901 ccgtgttacc gccgtgaaag ggcggtgtct taaccgcttg accaacgggc caggtaaatt
      961 tgctacggag agtaagggat tcgaaccctt gagacagttt ggcaccatct acatgatttc
     1021 caatcatgct ccttcggcct ctcggacaac tctccagagt gaaagaagct caatactctt
     1081 tctcaaaatg ag
//
LOCUS       DAFLVO010000218         1090 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.224, whole genome shotgun sequence.
ACCESSION   DAFLVO010000218 DAFLVO010000000
VERSION     DAFLVO010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1090
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.224"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(362..435)
                     /locus_tag="L1U99_003085"
     tRNA            complement(362..435)
                     /locus_tag="L1U99_003085"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(399..401),aa:Ile,seq:cat)
BASE COUNT          393 a          171 c          170 g          356 t
ORIGIN      
        1 taccactcca attataagtc tttttcccat tattttttac agttatatgg tatgcttttt
       61 aatggcttca aatataaaag agtttaaagc gtaacacact tatggggaag tggtttttgg
      121 ggaacgcttt aaactcttct ttattattat ctcacaatat aacccaaatg tctttccatt
      181 taaaaatcaa agtaaaactt ttcaaatata cagaagtata actatgtgaa acatcctttc
      241 attaatccat aaaaggatac ataaaaaagc cactcatttg agtggcaatg aagaaaagct
      301 ttagcttgta taatactctt caaaaaattc taacacagaa cgattcaatt ggctacatta
      361 atgtaccctg taggactcga acctacgacc ggacggttat gagccgtctg ctctgaccaa
      421 ctgagctaag ggtagtggtt gttgccacat aaagccataa acaatcaacc agtagaatgc
      481 gtggcaacaa acctgttatc gcatatcttg gagtgtgact atttatgagt gatagtgaag
      541 atatgcgtct ccatatatgt atggttgaga cagataaaca tgtatgaaaa acgttgttaa
      601 atcaacgttt ttttattttg gtcaaggaga gaaaagtaga gaaatacaaa attttttgca
      661 ttgattttgc attcaaaaaa acattcaaac atttagaaat ccccaatacg tattcaggaa
      721 aatctatttt aaggtttaca aaaagaactt ttgttcgtac actctttttg aggtgaactt
      781 ttatgctgat ggaaggaaaa acacaattat ggtttaagca tgttccttca aataagtttt
      841 ttaattataa actctagaga aattaattca tcctaacata aaataattgt tcactcaaaa
      901 gtttttctag aacaattaaa acagcaggct tcacattcgc tatacatttg taagaagtaa
      961 taattcctgt actaaaaggc ataattgctt taattatttt ttgacttctc ttcaaacaca
     1021 agaagtagtt gtgtaataat tgcagaaata aggattccaa taatagatat aaaatttgac
     1081 atggaaacgt
//
LOCUS       DAFLVO010000219         1081 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.225, whole genome shotgun sequence.
ACCESSION   DAFLVO010000219 DAFLVO010000000
VERSION     DAFLVO010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1081
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.225"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..528)
                     /locus_tag="L1U99_003086"
     CDS             complement(<1..528)
                     /locus_tag="L1U99_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBN1213560.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(627..977)
                     /locus_tag="L1U99_003087"
     CDS             complement(627..977)
                     /locus_tag="L1U99_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HBN1213561.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
BASE COUNT          395 a          202 c          173 g          311 t
ORIGIN      
        1 acgtatagtc atttttctta ttctgatgaa attgataatc tcctggatgc ccatgaaaat
       61 caaaataaag ccgaatattt ggaatagaag catcaaactt ttgaatggat tgaacaataa
      121 gacgaatccg ccaatcaaca acagaatact actataaaca ctccaacttt tagcttttgt
      181 attcatgctg aagaacaact ggaacaagct gttgatgata acagctaatc caagaagaat
      241 cggcaggata gaaacgattg caggtgcaaa agcatagacg atcagagcta agatcaggaa
      301 aaaaagacca ctgaacagac cgatactcca agaacctgtt ttccttttaa aacggtaagc
      361 ctcaaaaaga ttcaacaacc caagcaaaac aagataggcg gtgatcagat aaccgataaa
      421 atgaaaaaca gcagaagggt ttagcacaat cgcaatccca gaaataatat aaacagcagc
      481 tcttaataag gcgtattttt gaatattttg tttaatcgtc tcaaacatat aagaaaacct
      541 cctttgactt attttaacgt gaactagtca ttttaccaaa ttaaatgtta caaaatgagc
      601 gaaggagaag aatatctctg gaaaaatcaa cttctgagga tcttttccat ttttttgcct
      661 tttgctagct catcgatcat tttatctaaa taacgaattt ctttcatcaa gttatcctcg
      721 atgtcttcta ctcgtacacc acaaacaaca cctgtaatca aggaacgtga aggattgggg
      781 acaggggctt ccgcaaaaaa ttgttcgaaa gtcacttgtt tttgtagttg atattctagt
      841 tctgtttggg aataacccgt cagccaacaa atgatttcat ctacttcctc ttttatacga
      901 tcttttctct ccgcttttgc tacatacata ggataaacgc ttgcaaaact tgtcgtaaaa
      961 atacgatttt gcgccataat cagtcacctt tctttttttc aaattattta ctacttatag
     1021 tatataagaa aaagagaaga aaaagcgatt attcaaaaaa acaaaaagga ttgtgacaaa
     1081 a
//
LOCUS       DAFLVO010000220         1081 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.226, whole genome shotgun sequence.
ACCESSION   DAFLVO010000220 DAFLVO010000000
VERSION     DAFLVO010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1081
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.226"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            254..>1081
                     /locus_tag="L1U99_003088"
     CDS             254..>1081
                     /locus_tag="L1U99_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBN1213562.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     "
BASE COUNT          379 a          152 c          185 g          365 t
ORIGIN      
        1 ggtaataagt tattctttta ttactatgtt tgggttttat agcaaagaaa gtttaataag
       61 agtttggacc tagcaaacaa tattaatgag gtcattaaat cttattatct ttagtgatat
      121 aacgaaatat ctacacagac aaaatgatag cgtaaaatat tttgtgtaaa tagatattta
      181 gggtagaaaa aaagaaagtc cattctgtaa aattaaagtt accacaaccg aaattttata
      241 ggaggacttt ctcatgccca attttactac agaaattatg gaaacactaa tcaataaagg
      301 tgatttagat gaattatttc gatgtcattt agaattagct gttaattcat tattgcaggc
      361 tgaattaaca gcttttcttg attatgaaaa atatgatcgt gctgggttca attcaggtaa
      421 ttcccgtaat gggaattatt cacgttcatt cagaacagag tatggagaat taaatttggt
      481 aattcctaga gatagaaatg gtaagttttc tcaacaaact ttacctgctt ataaaagaac
      541 caatgactct ttagaaacca ctattattca gctatttcaa aaaggaatta ctatgtctga
      601 aatctctgaa ttgattgaaa aaatgtacgg gcatcactat acgccacaaa ccatttcaaa
      661 tatgactaaa atagtttctg aagatattat tgcctttaaa gaaaggtcct tagaatccag
      721 atactctgtc atttttatgg atgctactca cattccttta aaaagacaaa ctgtttcaaa
      781 agaagcagtt tatattgtaa ttggcattcg attagatgga accaaagagg ttcttgggtt
      841 tagtcttgct ccaactgaat ctgcttatgt ttggaaagag attcttcaag acctaaaaga
      901 ccgtggttta aaagaggttt tattagtcgt aactgatggt ttaagtggca ttaacgatag
      961 tattcatagt gtttatccaa atgctcaatt tcaacaatgt tgtgtccata tatctagaaa
     1021 tatcgctcat aaggttcgtg ttagtgatcg acaagaaatc tgtagcgatt tcaaattagt
     1081 t
//
LOCUS       DAFLVO010000221         1059 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.227, whole genome shotgun sequence.
ACCESSION   DAFLVO010000221 DAFLVO010000000
VERSION     DAFLVO010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1059
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.227"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(37..993)
                     /locus_tag="L1U99_003089"
     CDS             complement(37..993)
                     /locus_tag="L1U99_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213563.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          344 a          176 c          160 g          379 t
ORIGIN      
        1 ttagaaaaag cagtcggact ttctaaaaga agttcactat tcgatcctgt cgatgatttc
       61 ttcaggaaaa tcgtctattt gcttgtcaat tttgctgtct ttgtatttct cttcttggat
      121 agtcaacaaa atctttgtaa gattccccca gtctactgct cttggcggat cgagccaaac
      181 cactacttga gatgcacttt cttcatatag attattccta ttcgtgatta taacatccgg
      241 gaactcaggc tttcctgcct ctatcacttc cgtgttcaga ttaatgtaca agcttaaatt
      301 tttcttgata aattgattat aggcagcacc ataagaaaaa tcgatgatga tctttactgg
      361 ttcagaaatc agttgaatgg gtatgtgatt gatcaataat aataaataac tgaaaaaaag
      421 aaaaaattta tcttgaagca actctttgcg ttttgacgtt agatcattta tatactctat
      481 caaatagcaa taaaatgctg gatagttttc tctaaaaaaa gaaacatcaa gtggaaattc
      541 atcagcttta ttaatagtgt aatgcaaaag tttaaaatgt attttggtta actctcttcg
      601 gatcaattgg ctcgtctctt ctcgcaacag attaaactga ttttcaaaac tttcaatgaa
      661 tcgttcattc aaccattcga ttgtttcatc ttcatttttt ctcaagtatt tttgatccaa
      721 tttatcatga agataaagcc aagagagtgt cttattgata aaaataacgg atttttctcc
      781 taatactcct tttaagtggt aaaatcctat atccgaaaaa aatagcgact gattgctagc
      841 aatatctaaa gaatcagctt gttcagccaa caggttgatt gctaaaaagt ggaataattt
      901 ctttttttca taagcagaca gaggataata ctgttttaaa tcttttaaca ttttttctgt
      961 ttttataatt ataggtagcg tatacaattc cacaaaactt atctctgttg agttaaaaag
     1021 attatataaa aaaagccgaa tgtttttagg attccctgt
//
LOCUS       DAFLVO010000222         1045 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.228, whole genome shotgun sequence.
ACCESSION   DAFLVO010000222 DAFLVO010000000
VERSION     DAFLVO010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1045
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.228"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="L1U99_003090"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="L1U99_003090"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBN1213564.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          376 a          132 c          182 g          355 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgtaggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaac
//
LOCUS       DAFLVO010000223         1035 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.229, whole genome shotgun sequence.
ACCESSION   DAFLVO010000223 DAFLVO010000000
VERSION     DAFLVO010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.229"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..>1035)
                     /locus_tag="L1U99_003091"
     rRNA            complement(<1..>1035)
                     /locus_tag="L1U99_003091"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          218 a          324 c          234 g          259 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatgcaccgc gggtccatcc atcagcgaca
     1021 cccgaaagcg ccttt
//
LOCUS       DAFLVO010000224         1027 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.230, whole genome shotgun sequence.
ACCESSION   DAFLVO010000224 DAFLVO010000000
VERSION     DAFLVO010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1027
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.230"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            111..>1027
                     /locus_tag="L1U99_003092"
     CDS             111..>1027
                     /locus_tag="L1U99_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213565.1"
                     /translation="MELLEKAYSSTELIDSYEYEDLKYIKDQRNYSAHPVVTYNGNTW
                     ELRDITKETCQDVIRKSYEIIFLKNPILGKKVTIEIIQYASRIHAMSVTPEEFHSALK
                     NSYLNKLSEKAKENLCKTAFKFVFQLSYGNEEADRDRESTFRLLNALIFDNKEFYLNI
                     LKKEIAKYRFTAESREEINKSLGENQQITYTKGFFLLTFIATHPELQHDFSDETIQNL
                     QISINDFKPKQQVLTEIEYYYRLRSLAVLGNNNEELQNHLNSLVDPILQQKMRVSSLP
                     SSTLETIYNQYLYFGEKEMFIDFMIEHLT"
BASE COUNT          423 a          153 c          150 g          301 t
ORIGIN      
        1 ttgataaatt atctgattta gcaaatattt acgaggataa tacttctaag aaaattttag
       61 aagatatagc tagactaaga aaaagtgatc caaactctcc aaaatgggaa atggaactac
      121 tagaaaaagc ttatagttca actgagctaa ttgatagcta tgaatatgag gatttaaaat
      181 atattaagga tcaaagaaat tattcagctc atcctgtagt cacttacaac ggtaatactt
      241 gggaattaag agatataaca aaagaaactt gtcaggatgt tatacggaag tcctatgaaa
      301 ttatattcct aaaaaatcca atattaggaa aaaaagtaac gatcgaaatt atacaatatg
      361 caagtcgcat acatgctatg tctgttacac ctgaagaatt tcactctgca ctaaaaaata
      421 gctatctaaa taaactaagc gaaaaagcca aagaaaacct atgtaagaca gcctttaagt
      481 ttgtttttca attatcttat ggaaatgagg aagcagatag agatagggaa agtactttca
      541 gactacttaa tgccctaatt tttgataata aagaattcta tttaaatatt ctaaaaaaag
      601 aaattgcaaa gtataggttc acagctgaat caagagagga aattaataaa tcacttggtg
      661 aaaatcaaca gatcacgtat acaaaagggt tctttttact tacttttata gctacccatc
      721 cagaattaca acatgatttt tcagacgaga caattcaaaa tttacaaata tcaataaatg
      781 attttaaacc gaaacaacaa gtactaacag aaatagaata ttactaccgt ttacgttccc
      841 ttgcagttct aggaaacaac aatgaagaat tacaaaatca cttaaatagt ctagttgatc
      901 ctatactcca gcaaaaaatg agagtttctt cgctaccatc ttcaacatta gaaacaatat
      961 ataatcaata tttatatttt ggtgaaaaag agatgttcat agattttatg atcgaacatc
     1021 ttaccga
//
LOCUS       DAFLVO010000225         1017 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.231, whole genome shotgun sequence.
ACCESSION   DAFLVO010000225 DAFLVO010000000
VERSION     DAFLVO010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1017
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.231"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
BASE COUNT          353 a          171 c          152 g          341 t
ORIGIN      
        1 aattgtctcc tttaattcat ctataatttc atccacgata ttttaatccg ttctacaatg
       61 catatctgat atgcattgac tgtctaactc atatgtgaat gatttataaa atatcccaac
      121 gtctcatcta aagaaatgtt gatcgtcagc aaggagctaa aaaatacgaa tatatttctt
      181 ttgtagtaaa atcggactgg tttgcatatc attttcttcg taaatatcaa aatcatgtta
      241 actactatca attactaata aaaactacca ctttaagcgt taagaactgt taagtttagt
      301 taagtgagga tagttcacaa aatccattgt taaacttcac gaaagtggta aaactcaaaa
      361 tgctttatat aggattacag catcgctctt tcttcgattg cgcgttgggt aaaaaatatt
      421 atgaagtaaa aattgacgat gacacgttcc ttacggctca tcagatgaaa cagctacaaa
      481 aacgaaatga tcaactcgaa gaaaatttaa ttctaaaaaa gcgattgcca tattcacgcc
      541 tcgctcgacg aactattaaa ggtcaagatt tacctgaaga tcatcctttt taggaaattg
      601 aagcttttta tgttgcacaa tgcatttata atactacaat gatgttttca ccagatattc
      661 ttctagggtg cggtgtaatg aaacagatac acttgcaaaa gaaaattcac cgcgaattta
      721 ctaaaattat gaataattat gttaatcttc cgaaattttt ttccaaaatt aagggatcaa
      781 gctggtgtta tagattgttt aaggttggca aaaaaataac ttctttttaa acaattatag
      841 aaaaccgata ctctgttaag ttggttgaca cggtgtcgat ttttatgact ttcttattct
      901 gaaacttcac taacggacag tacctaaaaa gtctatagta tggacgttta cgagtactat
      961 tttatcaaaa atgctgctca tttcaactta tatgttttag tgaactaccc ccactta
//
LOCUS       DAFLVO010000226         1001 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.232, whole genome shotgun sequence.
ACCESSION   DAFLVO010000226 DAFLVO010000000
VERSION     DAFLVO010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.232"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            370..1001
                     /locus_tag="L1U99_003093"
                     /pseudo
     CDS             370..1001
                     /locus_tag="L1U99_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          181 c          184 g          294 t
ORIGIN      
        1 gtttcaaagt tagtagagaa aatgtagtta tatatttaaa tttttaccag aaagaaatga
       61 acaccttcaa ttatctaaat ctcgaaaatg gttagatgta atcatcagga aaaacaatct
      121 taaacgaatt actattcatg gtcttagaca cacacatgct agcttgcttt tagcaagcta
      181 gtgcaaatat taaagatgtg caagagcgtt taggccactc ttctattcaa atcattatgg
      241 atctatatat tcatattaca gacaaaagaa aagaagaaac cgtagcgcaa ttcgcaaaat
      301 ataggctcta taatttatgg gactgatgaa tcaaaattga ttcttcagtc ccattgttat
      361 tttaggtata tgattcgtac attgaaagag ttgaaaaact atcttccgaa gccgtcaaaa
      421 aggaccctgc caaaagtatt gatggtggat gaatttcgtt cgcacgcttc aattgtggat
      481 aaaatgagct ttatttgtgc ggatggcgag actggaaaac tcattgatat tttgcctaca
      541 cgaaaattgt ctcgattaac acactatttt agtcgctgtg caaatcctga agcggtggaa
      601 tatttagtga cagatatgaa cgccgcctac ttccaactga caaaacgtgt cttaccaaat
      661 gcgaaagtcg tcattgattg ttttcatatc atcaaacatt tgaatcaggc gttcaatgat
      721 tttcgtgtac aagaaatgaa aagattacac cagttagggc aacgacggga agccgagaaa
      781 gtgaaaaaga actggcgctt tcttctaaaa aaccgtcaaa aaatcaatca ctatgattac
      841 aaaacatggc gcagttttcg tgcacctaaa tacccgctac tcactgaagc aatgatgatt
      901 gatcgattgc tggcattttc aacgccttta aaggacgcct atactttttt ccatgagctg
      961 accgaagcct ttagagacaa ggaatcagac ttatttttta c
//
LOCUS       DAFLVO010000227          991 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.233, whole genome shotgun sequence.
ACCESSION   DAFLVO010000227 DAFLVO010000000
VERSION     DAFLVO010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.233"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(21..94)
                     /locus_tag="L1U99_003094"
     tRNA            complement(21..94)
                     /locus_tag="L1U99_003094"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58..60),aa:Ile,seq:cat)
     gene            complement(108..181)
                     /locus_tag="L1U99_003095"
     tRNA            complement(108..181)
                     /locus_tag="L1U99_003095"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(145..147),aa:Met,seq:cat)
     gene            complement(209..281)
                     /locus_tag="L1U99_003096"
     tRNA            complement(209..281)
                     /locus_tag="L1U99_003096"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(246..248),aa:Ala,seq:tgc)
     gene            complement(301..374)
                     /locus_tag="L1U99_003097"
     tRNA            complement(301..374)
                     /locus_tag="L1U99_003097"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(338..340),aa:Pro,seq:tgg)
     gene            complement(384..457)
                     /locus_tag="L1U99_003098"
     tRNA            complement(384..457)
                     /locus_tag="L1U99_003098"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(421..423),aa:Arg,seq:acg)
     gene            complement(468..553)
                     /locus_tag="L1U99_003099"
     tRNA            complement(468..553)
                     /locus_tag="L1U99_003099"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(517..519),aa:Leu,seq:taa)
     gene            complement(570..641)
                     /locus_tag="L1U99_003100"
     tRNA            complement(570..641)
                     /locus_tag="L1U99_003100"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(607..609),aa:Gly,seq:gcc)
     gene            complement(653..725)
                     /locus_tag="L1U99_003101"
     tRNA            complement(653..725)
                     /locus_tag="L1U99_003101"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(690..692),aa:Thr,seq:tgt)
     gene            complement(743..824)
                     /locus_tag="L1U99_003102"
     tRNA            complement(743..824)
                     /locus_tag="L1U99_003102"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(788..790),aa:Leu,seq:tag)
     gene            complement(832..904)
                     /locus_tag="L1U99_003103"
     tRNA            complement(832..904)
                     /locus_tag="L1U99_003103"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(869..871),aa:Lys,seq:ttt)
     gene            complement(908..980)
                     /locus_tag="L1U99_003104"
     tRNA            complement(908..980)
                     /locus_tag="L1U99_003104"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(945..947),aa:Val,seq:tac)
BASE COUNT          260 a          283 c          235 g          213 t
ORIGIN      
        1 tgaaacttac aacgccacaa tggaccttgt aggactcgaa cctacgaccg gacggttatg
       61 agccgtctgc tctaaccaac tgagctaaag gtccaggctc ttaaaaatcg cggcggaggg
      121 gatcgaaccc ccgacctccc gggtatgaac cggacgctct agccagctga gctacaccgc
      181 gaaaaagata ttcattattt aaatgaaatg gagcctagcg ggatcgaacc gctgacctcc
      241 tgcgtgcaaa gcaggcgctc tcccagctga gctaaggccc cgtgtttaaa tttataatta
      301 tcgggaagac aggattcgaa cctgcgaccc cttggtccca aaccaagtgc tctaccaagc
      361 tgagctactt cccgtttaat taacgcgccc aagaggagtc gaacccctaa ccttttgatc
      421 cgtagtcaaa cactctatcc agttgagcta tgggcgcata tttgaaatgc cgaggaccgg
      481 aatcgaaccg gtacggtgat cactcaccgc aggattttaa gtcctgtgcg tctgccagtt
      541 ccgccacccc ggcgcgattg ctttggcaaa gcggaaaacg gggttcgaac ccgcgacccc
      601 caccttggca aggtggtgct ctaccactga gctatttccg cgtgtttaaa gatgccggct
      661 aaaggacttg aaccctcgac cctctgatta caaatcagat gctctaccaa ctgagctaag
      721 ccggcatgta aaacttaaat tatgcgggtg aagggacttg aacccccacg ccgtaaggcg
      781 ctagatccta aatctagtgc gtctgccaat tccgccacac ccgcaaaaat atgagccgta
      841 cagggctcga acctgtgacc ctctgattaa aagtcagatg ctctaccaac tgagctaacg
      901 gctcatatgg aggttaacgg gatcgaaccg ctgaccctct gcttgtaagg cagatgctct
      961 cccagctgag ctaaacctcc atggataact t
//
LOCUS       DAFLVO010000228          988 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.234, whole genome shotgun sequence.
ACCESSION   DAFLVO010000228 DAFLVO010000000
VERSION     DAFLVO010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..988
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.234"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            78..617
                     /locus_tag="L1U99_003105"
     CDS             78..617
                     /locus_tag="L1U99_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213566.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            614..952
                     /locus_tag="L1U99_003106"
     CDS             614..952
                     /locus_tag="L1U99_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HBN1213567.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT          358 a          130 c          187 g          313 t
ORIGIN      
        1 catttttaaa aggagatgta taatcgagat ttagaaagcg ttttcctcaa aatttaatga
       61 attaggaagt gattactatg aaaaaattat ttagcgcact ttttattctg ttatttggct
      121 ttattggtat tgggacttct ggaaatatag ttaaagctag cacgatggtt gaacaaacaa
      181 gtgaaatggc aaaaactttt agtcaattaa caccagaaga acaaagttac ttcaaatcca
      241 aaggatttag tgataaagat actttttaca ctcaaaagat agagcctcaa gatccgaaaa
      301 cacgtttttc tgcaaatgta ttgcggttaa ccgcatctac taaaaaaatt actaatacgc
      361 aggggcggac agaatatatt ataacaagtc ccaattcggc gatgtatcgt atttctacac
      421 gcttgagttt aggtagtgca aaatcatata ctcaaacagt aaatctagct aattcttatg
      481 gttatggtgg aggaatgtat tttacattta ctgggaaaag acaatattac agtgtaaaat
      541 tagctatgca agtttataat acatttggtg tagggtcagt ctcttgcact gcgggaggat
      601 tgacaatagg aaaatgataa tttcttacta tgtcttaaat agaagtgatg atgaaggact
      661 cttcgttttt caatcattac atgaggatac gatgctaaaa gagttttata atcggattaa
      721 gaataaacag atagaaacaa atttatattt tttaagtgac tctatcttgc cttttattag
      781 caaccctaaa attcttaact tgttgcagac aaaagatttg aaaagtttac cgattattgt
      841 cattgatgag gaaattgtaa aatatggcgc ttatctaagc gtagaagaat tagaaaaatt
      901 aactaacatt ggaatgagta ttcaggagga taatggggta catggaacat agaatgaata
      961 tgcacagttg agaacggaat ttgacatt
//
LOCUS       DAFLVO010000229          984 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.235, whole genome shotgun sequence.
ACCESSION   DAFLVO010000229 DAFLVO010000000
VERSION     DAFLVO010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..984
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.235"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..>984
                     /locus_tag="L1U99_003107"
     CDS             <1..>984
                     /locus_tag="L1U99_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBN1213568.1"
                     /translation="EPGDFIMSGAGTIGRISRVPKQIKPGVFNQALIRLRINKEITDS
                     EYFIQFIRADFMQRKLTGANPGSAITNLVPMSEVKKWIVQFPILEEQKKIGNFFKQLD
                     DTIALQQRKLDLLKETKKGFLQKMFPKNGAKVPEIRFPGFTEDWEQRKFKEFSKKTGK
                     KNTKDLDFPAYSVSNKAGLISQTEQFDGSRLDDLEKTNYKFVEPNEFAYNPARVNVGS
                     IAFNNLGMTVIVSSLYVVVKMSEDLDNEFILQFIKSPTFIKEVKRNTEGSVREYLFYE
                     NFANIKFPFTRNKEEQQKIGAFFKQLDDTIALHQRKLDLLKETKKGFLQKM"
BASE COUNT          375 a          159 c          189 g          261 t
ORIGIN      
        1 agaaccaggc gattttatca tgagtggcgc tggaacaatt gggagaattt caagagtacc
       61 aaagcaaata aaaccgggtg tattcaatca ggctttgatt agacttagaa taaataaaga
      121 aatcacagat tcagaatatt ttattcaatt tattcgtgca gattttatgc aaagaaaact
      181 cacaggagct aatccaggtt cagcaattac aaatctcgta ccaatgtcag aagtgaaaaa
      241 atggatagta caatttccaa tattagaaga acaaaagaaa attgggaact tcttcaaaca
      301 actggacgac actatcgctc ttcaacaacg taagctagat ttattaaagg aaacgaaaaa
      361 aggattctta caaaaaatgt tccctaaaaa cggagcaaaa gtgccagaaa ttcggtttcc
      421 tggatttacg gaagattggg aacagcgtaa gttcaaagag tttagtaaga agactggaaa
      481 aaagaacacg aaagatttag acttccctgc ctattcggta agtaataaag caggtttaat
      541 ttctcaaaca gaacagtttg atggtagtag gttggatgat ttagaaaaaa caaattataa
      601 attcgttgaa ccaaatgaat tcgcctataa tccagcaaga gtaaacgtag gatcaattgc
      661 atttaacaat cttggtatga cggtcattgt tagctctctt tatgtagttg tgaaaatgag
      721 cgaggactta gataatgagt tcatacttca gtttatcaag tcaccaacat ttatcaaaga
      781 ggtcaagcgc aacactgaag gaagcgtacg agaatactta ttctatgaga atttcgctaa
      841 tatcaagttt ccttttacta ggaataaaga ggaacaacaa aaaatcggcg ctttcttcaa
      901 acaactcgac gacacgatcg ctcttcatca acgtaagtta gatttgctga aggaaacgaa
      961 aaaaggcttc ttacaaaaga tgtt
//
LOCUS       DAFLVO010000230          943 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.237, whole genome shotgun sequence.
ACCESSION   DAFLVO010000230 DAFLVO010000000
VERSION     DAFLVO010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.237"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..296
                     /locus_tag="L1U99_003108"
     CDS             <1..296
                     /locus_tag="L1U99_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1213569.1"
                     /translation="FIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKL
                     YSANAKDPQRRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            complement(320..670)
                     /locus_tag="L1U99_003109"
     CDS             complement(320..670)
                     /locus_tag="L1U99_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBN1213570.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(664..927)
                     /locus_tag="L1U99_003110"
     CDS             complement(664..927)
                     /locus_tag="L1U99_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HBN1213571.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
BASE COUNT          289 a          184 c          136 g          334 t
ORIGIN      
        1 aattcattaa agatttgatc attcaaattt tggccatgat cgctgaacaa gaacgtaccg
       61 aatctaaacg acgtcaggca caaggcatta agattgcaaa agcgaacggt gtttataaag
      121 gacgtcctaa gctatacagt gccaatgcaa aagatcccca acgtcgtctt gtttataaaa
      181 acatcgttga ggatctaaaa aaaggtgttg cgatcgctaa gattgcaaaa gactacaatg
      241 ttacgagaca aaccgtatat agaataaaaa aagacagcat ggtcaatcac gaatagttga
      301 tcatgctgct gtttctattt tatttgctta ctttttgaaa aactgttcta actttcatca
      361 ataactcctc aactaaacta tcatgcgctt tttccaaaaa aatacactct ctggcttcat
      421 aatcaattgt cgttagttga tctaataata cttttcctgt tgtcttcatt tcatattctg
      481 agtttatatt tacatatagc ggatagtttc tagttgtact agaaattgga gcaactgtaa
      541 caacgttact ataatccgca ataatatcat gacttaaaac aatataaggt cttttacctg
      601 tctgttcgtg tccagatcga ggtgctgtat tcaataatag aatatcgcct tgtctaggtt
      661 ttctcaccat ttttcattac ctactgcttc acctaaattt tgaatcgtca catgatttct
      721 ttcatcagtg taattttcaa ataactgttc aattgttaat tcattttcta tattagccgc
      781 ttcgataatt agccgcttct gaccgtttac ttcttcttgt attatcttca ctttgtcttc
      841 tgtatgaatt ccaagatatt ccataatata ctttggcaat ctaaggccat tactatttcc
      901 ccattttttt ataggtaaca tttccatagt agacacctct ttc
//
LOCUS       DAFLVO010000231          943 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.238, whole genome shotgun sequence.
ACCESSION   DAFLVO010000231 DAFLVO010000000
VERSION     DAFLVO010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.238"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..>943
                     /locus_tag="L1U99_003111"
     rRNA            <1..>943
                     /locus_tag="L1U99_003111"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          293 a          187 c          274 g          189 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact agg
//
LOCUS       DAFLVO010000232          857 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.241, whole genome shotgun sequence.
ACCESSION   DAFLVO010000232 DAFLVO010000000
VERSION     DAFLVO010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..857
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.241"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..116
                     /locus_tag="L1U99_003112"
     CDS             <1..116
                     /locus_tag="L1U99_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBN1213572.1"
                     /translation="KILIIDDVYTTGQTLFHAADCLQNAQPKIIRTISLAR"
     gene            244..795
                     /gene="raiA"
                     /locus_tag="L1U99_003113"
     CDS             244..795
                     /gene="raiA"
                     /locus_tag="L1U99_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBN1213573.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
BASE COUNT          306 a          151 c          177 g          223 t
ORIGIN      
        1 aaaaaatatt gattattgac gatgtctata caacaggaca gacgcttttt catgcagcag
       61 attgcttgca gaacgcacag ccgaaaatca tccgaaccat ttctttggca agatgaatca
      121 gatgtggaaa tttgatagcg atttaatttg caaataacct agagttcgat ataatagaat
      181 taagaagagg gaaagagtgg tccttctcct tcttgattgt ggtagacgaa aggggtaatt
      241 tttatgttta gatataatgt acgcggcgaa aatatcgaag taactgaagc gattcgcgac
      301 tacgttgaga aaaaagtagg caaactagaa cgctatttca gtgacgcacc cgatgcaacg
      361 gcgcatgtga acttaaaagt ttatacagaa aaaacagcaa aagtggaagt aacgatccca
      421 ttaccttatc ttgtattacg tgccgaagaa acttctccag atttatacgc aagtatcgat
      481 ttggttgttg acaaattgga acgccaaatc cgcaaattca aaacaaaaat taatcgtaaa
      541 tcccgtgaaa cgggcatgaa tactgcagat gctgctgctt tattcaatga agaggacgaa
      601 aacgaaaatg attctgaatt agatatcgta cgtacgaaac gcctttcatt gaaaccaatg
      661 gatagtgaag aagcagtctt acaaatgaac atgctgggac ataacttctt tatttttgaa
      721 gatgcagaaa caaatggtac aagtatcgtt taccgccgta aagatggaaa atacggactg
      781 attgaaacag actgatcagc cttacttaaa taacaacgaa aacttgcagc agctactgac
      841 agctgccgca agttttt
//
LOCUS       DAFLVO010000233          827 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.242, whole genome shotgun sequence.
ACCESSION   DAFLVO010000233 DAFLVO010000000
VERSION     DAFLVO010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..827
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.242"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..548
                     /locus_tag="L1U99_003114"
     CDS             <1..548
                     /locus_tag="L1U99_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBN1213574.1"
                     /translation="TALENKEQKISILNSQLSSNNQTLEQLRTNIEVSKQKVASLEND
                     KNQLVSEKTNLENQLSAKDSELQGKQNEINAKIDEINQKVAEINRLNSDWNNRLQNEK
                     NKFNEEQSTINSLNQQINQMLSEKNNIQNQLQATQQKLEEEKSKNSSLNNYIEKLQKA
                     KNDVEDTANKAQQIVNEHTIQ"
BASE COUNT          376 a          103 c          116 g          232 t
ORIGIN      
        1 acacagctct agaaaataaa gagcaaaaaa ttagtatttt aaattcacaa ttgtcttcaa
       61 acaaccaaac tcttgaacaa ctaagaacta atattgaagt ttccaaacaa aaagtggcat
      121 ctttagaaaa cgacaagaat caattagtat cagagaaaac taatttagaa aatcaattgt
      181 cagcaaaaga ctctgaattg caaggaaaac aaaatgaaat taatgcgaaa atagacgaaa
      241 ttaaccaaaa agtagctgaa ataaatcgat taaatagcga ttggaataat cgtttacaaa
      301 atgaaaagaa caaatttaat gaagaacaat ctactattaa tagtttaaac cagcaaatta
      361 atcaaatgtt gagtgaaaaa aataacattc aaaatcaact gcaagctact cagcaaaagc
      421 tagaagaaga aaagtcaaaa aatagtagtt tgaataatta cattgaaaag cttcaaaaag
      481 ctaaaaatga tgtagaggat accgcaaata aagcacaaca aattgtaaat gaacatacaa
      541 tccaatagat atagttttaa tttaacaaat ggtatgtttg gagataatga gatagaatat
      601 aaatgtcata atattataca atctaaacac cgtttccttt tctatttttg atgacatcag
      661 tatatagcta ctcgaaagag tagtcttttt attattctcg cttattattg atatgaaaat
      721 ttcgatttga caaaaggtac cgaataattt tgtaatatga attattatca agaagtaatt
      781 atgatgataa catatggaaa ctagttagta ataataacag gtgatta
//
LOCUS       DAFLVO010000234          825 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.244, whole genome shotgun sequence.
ACCESSION   DAFLVO010000234 DAFLVO010000000
VERSION     DAFLVO010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..825
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.244"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            228..>825
                     /locus_tag="L1U99_003115"
     CDS             228..>825
                     /locus_tag="L1U99_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1213575.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKL"
BASE COUNT          334 a           81 c          152 g          258 t
ORIGIN      
        1 ctttttgagt tgaaacgaag aaaaagtgtt agtagaaaat cgccttcgat tttccaacaa
       61 cacaaaatat tatagaaccc tttattctaa aggatttcaa ggtgtctgtt tgcatttatt
      121 agaaaaaaga aaaagtattg gcaacagaag gtgtcaccaa cactagatat tatagagcca
      181 taatatgctg tataatatct agtgtatagg cttaagtgga ggtatatatg aaaatattaa
      241 ctgttgaaga tgataatatg ataagagagg gaataagtga atatctttca gaatttggat
      301 atactgttat tcaagctaaa gatggaagag aagccttgtc aaaatttaat agcgatataa
      361 atttggttat cttagacatt cagatacctt ttataaatgg tttagaagtg ttgaaagaaa
      421 ttagaaagaa aagcaattta ccaattctaa tcttgactgc atttagtgat gaagaatata
      481 aaattgatgc atttactaat ttagtagacg gatatgtaga aaagccattt tcattgccgg
      541 tcttaaaagc tagaatagat tctttaatta agaagaatta tggacattta gagaagtttg
      601 aatataagga tctatcggtt aattttaata gctatacagc taaaataaat ggtgaagaaa
      661 tagatgtaaa tgcaaaagaa ctagaagtat taaaatgttt attggataat aatggacaag
      721 tgttaacaag aatgcaaatt attgattatg tatggaaaga tagcgaagaa actccttatg
      781 atcgagtaat agatgtatat ataaaagaac ttagaaaaaa attac
//
LOCUS       DAFLVO010000235          822 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.245, whole genome shotgun sequence.
ACCESSION   DAFLVO010000235 DAFLVO010000000
VERSION     DAFLVO010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..822
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.245"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..497
                     /locus_tag="L1U99_003116"
     CDS             <1..497
                     /locus_tag="L1U99_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213576.1"
                     /translation="IFGIEEVFVGDKCIFFDQPLLSDGYGIDETDIFAKVNSIFSGKK
                     ETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTLLISPISTISFSPSMMFEK
                     TINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLSEEKILLPENWAELRKLVE
                     YGII"
     gene            484..>822
                     /locus_tag="L1U99_003117"
     CDS             484..>822
                     /locus_tag="L1U99_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBN1213577.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNA"
BASE COUNT          276 a          113 c          124 g          309 t
ORIGIN      
        1 caatctttgg gatagaagaa gtttttgtcg gagataaatg tatctttttt gatcaacctt
       61 tattatctga tggttatggc atagatgaaa cagatatttt cgctaaagta aatagtatat
      121 tttctggaaa aaaagaaact ttaattaagc ttcatcctag agcaaggaca aatcgttatg
      181 gtgaaaaaaa catattgaat tccagtttac cgtttgaagt cttgctactt gaaaatgact
      241 tctcttcaac acttttgatt agtcctatat ctacaatttc tttttcacca tctatgatgt
      301 ttgaaaagac gatcaactct attatgttgg ctaaattaat tttaaatgaa tatacagcat
      361 tatctgaaga taaaaaagaa acattgacaa atattgttct tttctgtgaa cattataacc
      421 gtctatcaga agaaaaaatt ttactcccag aaaactgggc agaattaaga aagttggtag
      481 agtatgggat tatttaacac actttccaag tcaaaattag ttaagtccag tttctggtat
      541 actataggga atttttttat taagggaatt tcattcataa ctattcctat ttttgtaaat
      601 attactactc aagcagaata tggtttgatt aataatttca cttcatttgt atcaattttt
      661 tcgattcttg ttgggctaag cctaaattcg gcaattaata atgcaagttt tgactataaa
      721 gatgacataa atgaatttat gtcatcggta ctttctctag ctacactttc gttaattgtg
      781 ttcttattaa tagggaacat atattttttg ttttcaaatg ct
//
LOCUS       DAFLVO010000236          782 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.247, whole genome shotgun sequence.
ACCESSION   DAFLVO010000236 DAFLVO010000000
VERSION     DAFLVO010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..782
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.247"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..731
                     /locus_tag="L1U99_003118"
     CDS             <1..731
                     /locus_tag="L1U99_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBN1213578.1"
                     /translation="PSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMA
                     IFTNRLGTNKRGRLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMA
                     KVYLANCYTLEGRKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCA
                     ITLEEFQQANEIHCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLK
                     LNKVQLIRLNKYRVLAGNQELNLI"
BASE COUNT          305 a          126 c          148 g          203 t
ORIGIN      
        1 ctccctcaaa agggaaaacg gaattagaag aaacaagact ttataattca atggtattag
       61 gtatgcaaaa ttattatcag attgcaacga atgtaaatct ggattgtatg aaactgaata
      121 gagctgtaat ggctatcttc actaacagat taggtacaaa caaaaggggc agattgagaa
      181 aaacaggcag acaacttacg acaaaggagg caacaagata tggtaaatct aaaatgcttc
      241 ggtatgttgc tggcgagggc gaacctattt tccctgttgg atatatccaa cacagaaaac
      301 caatggcaaa ggtgtattta gcgaattgct acactctaga gggaagaaaa tttatccaca
      361 ccaatctaag tgttgataaa ttactgatgt accagttaat gaaattatct ttggaaaatc
      421 gcacaataga atacgcagac aatcgaattt cgctattttc tgctcaacat ggaaaatgtg
      481 ctataactct ggaagaattt caacaagcta atgaaataca ttgtcatcat attgtaccaa
      541 ctggagctgg tggaaatgac gattataaaa atcttatttt ggtaaaagag gcggtacacc
      601 gtctaataca cgctaaaaca gaagaaacaa tacaaaaata tatagctcta ttgaagctaa
      661 ataaagtcca gctcataaga ctaaataaat atagagtatt agctggcaat caagaattaa
      721 acttgatata ggtctactac ataaatactt ttcaatataa acacgatgga acgcggagtg
      781 cg
//
LOCUS       DAFLVO010000237          720 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.249, whole genome shotgun sequence.
ACCESSION   DAFLVO010000237 DAFLVO010000000
VERSION     DAFLVO010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.249"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            93..>720
                     /locus_tag="L1U99_003119"
     CDS             93..>720
                     /locus_tag="L1U99_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213579.1"
                     /translation="MTKKIEVYVDGSQEERDSFFDFFWKNSREYVKALNLVYKQLMFE
                     ELIKDAIKEMDQGYAEREESIQNRIEKLAYTDPIDQKKLDKAKAELSKLRNEKNKEAR
                     EILTQAIGLKSQTRTRDVAKKLDFDFGDFVDSANMKASKDFGNDFIGIVTGQRTPRIY
                     KNRNKYGLLPFRGRDIKIHKDDKFYIYLPKGFRFKVNLGSKPRKARDVA"
BASE COUNT          302 a           71 c          141 g          206 t
ORIGIN      
        1 tcatgtgaat atgagcttaa caattaaacg tatttatgat cttttatatg tttataaaca
       61 ttaatgaggt gctaaaattg acaacaataa ctatgacaaa aaaaatagaa gtatatgttg
      121 atggatcaca agaagaaagg gattcctttt ttgatttttt ttggaaaaat agtagagaat
      181 atgtaaaagc gttgaatctg gtatataaac agctaatgtt tgaagagttg ataaaagatg
      241 caattaaaga aatggatcaa ggttatgctg agagagaaga aagtattcaa aatcggattg
      301 aaaagttagc atatactgat ccaatagatc aaaaaaaact tgataaagca aaagctgaat
      361 tatctaaatt gagaaatgaa aaaaataaag aagcgagaga aatattaacg caagcgatag
      421 ggttgaagag tcaaacgaga acacgagatg tagcaaaaaa attagacttt gactttggag
      481 attttgttga ttccgcaaat atgaaagcta gtaaagattt tggcaatgat tttatcggaa
      541 ttgtgaccgg acaaagaacg cctagaatat ataaaaatag aaacaaatat ggattactac
      601 cttttagagg tcgagatatt aaaatccata aagatgataa gttttatatt tatttaccta
      661 aaggctttag gtttaaagtg aatttaggta gcaagccaag aaaagcaaga gatgttgctt
//
LOCUS       DAFLVO010000238          712 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.250, whole genome shotgun sequence.
ACCESSION   DAFLVO010000238 DAFLVO010000000
VERSION     DAFLVO010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..712
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.250"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..710
                     /locus_tag="L1U99_003120"
     CDS             <1..710
                     /locus_tag="L1U99_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1213580.1"
                     /translation="NANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLD
                     TPYNQPGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSDDK
                     PVIDPTRAGAANPTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTG
                     KELARVKADGIYRPDVNQAYNTLGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKG
                     GAQDFHDKRWYLNIPQR"
BASE COUNT          258 a          132 c          139 g          183 t
ORIGIN      
        1 ctaatgcaaa tagtcctgtg cagattgagt tacaacacac acatgataaa gcaacgtttg
       61 agaaaaacta caaggcatac gttgaattag ctagagattc agcaatgaaa tatggtattc
      121 cacttacact agacacaccg tataatcaac cagggatcaa atcgcattta tgggtaacac
      181 aaaatatttg gggcgatcat acagatcctt acggttatct ttctgaaatg ggcgtaagta
      241 aagaaaaatt agcctatgat ttggctcatg gatttaccga tgaaaatccg acaacttcag
      301 atgataaacc agtcattgat ccaactcgag caggtgctgc aaatcctacc ctgacagatg
      361 gaacaaatta cgcccacatt gatcagttcg gagaaatcga aaacgcaaac ttacatgtgg
      421 ctggttggca catcgctaac tataaatacg agtatatctt cattatggat tacaatactg
      481 ggaaagaatt agctcgagta aaagctgatg gaatatatag accagatgta aatcaagctt
      541 ataatacttt aggaaatgtt ggctatcatg tatcttttaa catgcgcaac ttccctaata
      601 agaaagtcta tgtaatgatg cgggcaacga atgatccaga agggaacact aaaggcggag
      661 cacaagattt tcatgataaa cgctggtatt taaatattcc gcaacgataa aa
//
LOCUS       DAFLVO010000239          680 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.252, whole genome shotgun sequence.
ACCESSION   DAFLVO010000239 DAFLVO010000000
VERSION     DAFLVO010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..680
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.252"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            158..>680
                     /locus_tag="L1U99_003121"
     CDS             158..>680
                     /locus_tag="L1U99_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBN1213581.1"
                     /translation="MDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDL
                     TQYNYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNY
                     SAFKSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDK
                     IIEIHLDYFGRVPT"
BASE COUNT          260 a           71 c          113 g          236 t
ORIGIN      
        1 agtaattttt tttgggttag ggtcaattgg aaagagacat ctaaaaaatc taataagcta
       61 tggaaaaaag aattctatta attttgatat aacagcttat agtagcagtg gaaaaaaaga
      121 gtttgaagaa ataacgtata ttcaaaatag agacgatttg gatacacatt atgatatagc
      181 ttttattaca aatccgactt ttaagcatct ggaaacacta aatgtaattg ttgaaaaagt
      241 tgattacata tttttagaaa aacctgcttt ttctgagagt attgatctta ctcaatataa
      301 ttatgattac aaaaatattt atgttgctgc tccactgagg tataaaaata tcatggaagt
      361 tgttcgtaat agtattcaaa gtaaaaaagt atattctgta agagctattt gttctactta
      421 tcttcctgat tggagaaaag gtactgatta tagaaataat tattctgcct ttaaatctat
      481 ggggggagga gtagaattag actgtataca tgaattggat tatattataa acctatttgg
      541 tttccctaaa tcagtaaaaa aacagtttgg taaatattcg aatcttgaaa ttaacagtaa
      601 tgatttagca acatatatat tgagatacga tgataaaatt atagaaattc atttagatta
      661 ttttggaaga gttcctacaa
//
LOCUS       DAFLVO010000240          625 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.256, whole genome shotgun sequence.
ACCESSION   DAFLVO010000240 DAFLVO010000000
VERSION     DAFLVO010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.256"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            1..625
                     /locus_tag="L1U99_003122"
                     /pseudo
     CDS             1..625
                     /locus_tag="L1U99_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          247 a          105 c          118 g          155 t
ORIGIN      
        1 gtaaagcaat ctaaaacgag tggttcattc aaagaaaaag ataatcttac gcctgaacaa
       61 aaagaattgt tagaactacg taaaagaaac cagcaattag aaatggaaaa tgatatttta
      121 aagcaagcag cgctgatatt cggacgaaga gacaagtaat cgatgcgaat aagcatcttt
      181 accctatatc agcgatgtgc agaatattag gtctatcacg tcagtcctat tattatcaat
      241 caaaaccaaa gaaagacgaa tcagaacttg aagaagtagt cgctgaagaa tttatccgca
      301 gccgaaaggc ctacggctca agaaaaataa aaaaagcctt atcaaaacga ggcattcaga
      361 tcagccgacg aaaaattagt agaatcatga aaaatagagg attaaaatcg agctatactg
      421 ttgcttattt taaagtacat cattctactt gcaatgaagc caaaacgaca aacgtattga
      481 atcgtaaatt cttaagagac aacccattag aagcgatcgt aacagacttg acttatgtac
      541 gagtcgggaa aaaatggaat tatgtctgtt tcattttgga tctgttcaat cgagaaattc
      601 tcggctattc ttgtggagaa cataa
//
LOCUS       DAFLVO010000241          610 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.257, whole genome shotgun sequence.
ACCESSION   DAFLVO010000241 DAFLVO010000000
VERSION     DAFLVO010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..610
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.257"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..146
                     /locus_tag="L1U99_003123"
     CDS             <1..146
                     /locus_tag="L1U99_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213582.1"
                     /translation="IVKTAIRNKAQIIRIIEPDKAYGEWAYYQLKEQLVNKGKRYGIE
                     VRS"
BASE COUNT          236 a           86 c          113 g          175 t
ORIGIN      
        1 aaatcgttaa aactgctatt cgcaataaag ctcaaattat tcgtatcatt gaaccagata
       61 aggcttatgg cgaatgggct tactatcaat tgaaagaaca actagtaaac aaaggaaaaa
      121 gatatgggat agaagtcaga agttagtaaa ttaaacaatc gttgatttgg caacgaaata
      181 gtgagggaaa atccactcac tgaagggtaa actccgtcaa gttgtgtgac cagacggaag
      241 gacgaatgtt gttgaggttt tagaaccata taaaacagca tgtttctcaa atttttagga
      301 taagggaaat tgctagcagt ttgttttaga accatataaa acagcatgtt tctcaaatga
      361 gtactttaaa ttaattgatg gcgttcctgc tttagaacca tataaaacaa catggattta
      421 aaacaagaag taagtcagtt ctccttttac tttagtaagg aaaaataaag tattctcaat
      481 aaaacttaaa ataagcaaac ctttgtttta atagctaatc gaagtaaaac ccaaagccat
      541 atgaacccct gaatcagcga aagtttatga tgatttggat tactaatagt ttaggaatta
      601 gatggtaaat
//
LOCUS       DAFLVO010000242          589 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.259, whole genome shotgun sequence.
ACCESSION   DAFLVO010000242 DAFLVO010000000
VERSION     DAFLVO010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..589
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.259"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            3..587
                     /locus_tag="L1U99_003124"
     CDS             3..587
                     /locus_tag="L1U99_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1213583.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT          182 a           90 c          142 g          175 t
ORIGIN      
        1 ttttgaaaat aggatacgcc cgggtatcta ctggtttaca aaatttggat ttacaagaag
       61 acagcctaaa taaatttggt tgtgaaaaaa tttttactga tcatatgagt ggggcaaaaa
      121 gtaatcgacc aggattagaa atggccattg attttgttcg ctctggcgat acacttgtcg
      181 tttggcgctt agatcgttta ggtagaaata tggaagattt gatttcaatc gtcaatcgac
      241 tgaatgagcg tggtgtgagt tttcatagta ttcaagaaaa tattacgatg gacaaatcaa
      301 gttctacagg acagctcatg tttcatttgt ttgcggcatt tgcagaattt gagcgtaatt
      361 tgatcctgga acgatccgca gcaggacgag cagctgctcg tgcaagagga cggtttggtg
      421 gtcgtcctga aaaattgtct gaacaagatt tggaattact gaagacttta gtggatagcg
      481 gtacacctat taagactatt gcggaacggt ggaacgtctc aagaaccacc atttatcgtt
      541 atttggcaaa aatggaggag aaaaatggaa agacaaattc tcattagtt
//
LOCUS       DAFLVO010000243          581 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.260, whole genome shotgun sequence.
ACCESSION   DAFLVO010000243 DAFLVO010000000
VERSION     DAFLVO010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..581
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.260"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(107..529)
                     /locus_tag="L1U99_003125"
     CDS             complement(107..529)
                     /locus_tag="L1U99_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213584.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
BASE COUNT          187 a          100 c           84 g          210 t
ORIGIN      
        1 gctgaacttg taaagctgat tcttctttcg gtaaattaat tttacttaga atatcgctat
       61 cttgataaaa atttggtgtg ttcacaaatt ctggcataaa aaatccctac tttctagtta
      121 aggttcctga ataagtcgca atccaattgt ttccagctga tttataactt tgtaaataca
      181 attttccata gtaccaataa ccatttcttt tttctttcca attccgtgat tgaggaggtc
      241 tagaaggcca accaacttta tcaaaaatca tcgttcctgt cactcgtatc gttttagaag
      301 ctgctcgagc aagtaatgga gaaactatta aataattttc agtaacagtt aagtcgttag
      361 ttgggttacc aatggctatt ccgttcctat ctaaaggagt taattcttgg ttattatcta
      421 ctacagtagt tggttcattt gtactatcag caaatgtagg aattgtagtt ccagttacac
      481 taattccaat agttaaaata cctaaagata aaataaactt atttttcatt gtctatcacc
      541 tcgaaatcaa aaataagaaa acgttttctt aataaatctt a
//
LOCUS       DAFLVO010000244          574 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.262, whole genome shotgun sequence.
ACCESSION   DAFLVO010000244 DAFLVO010000000
VERSION     DAFLVO010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..574
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.262"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
BASE COUNT          186 a           81 c           81 g          226 t
ORIGIN      
        1 ttttcttgat gtgatatcct tgtctttttt gtaatgtttt taacttattg cttttgcaaa
       61 atttatttac ctgttttctg gatcaacgat agtgtacatt atgctatcct tgtttggatt
      121 ttaggacgtt taaagaggca cttttttaca taacttaatc catagacctt ttaagcatgc
      181 tgtgagataa taataaagaa gagtttaaag cgcaccccaa accacttccc cataagtgta
      241 ttacgcttta aactctttta tatttgaatt cactaagaag cataccatat ttttgaaaaa
      301 aagtgagaaa aaaggcttat aattaggatt tagagtaatt aattagatgt ttattttata
      361 ggactgatac tatagattac aaatagtatc gtatttcgca atcttaaaat tatcttctta
      421 ctgtgaataa gataataaaa tttgtatttg tcctttttag gtaacttatt ttaatctata
      481 tacctttctg gatcaacgaa agtatacttt atatagtcat aacgccgatg gtaactatgc
      541 actgtaacga taatgctgct aaaatatctt ttta
//
LOCUS       DAFLVO010000245          551 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.264, whole genome shotgun sequence.
ACCESSION   DAFLVO010000245 DAFLVO010000000
VERSION     DAFLVO010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..551
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.264"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            87..>551
                     /locus_tag="L1U99_003126"
     CDS             87..>551
                     /locus_tag="L1U99_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1213585.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGK"
BASE COUNT          193 a           73 c          101 g          184 t
ORIGIN      
        1 tccaagctgt ttttggaggg aaagctgact tattaagtca agaaatcaat caaatattag
       61 gaaaagataa ttaggaggtt tttaatatgt ttgaaatttt caaaaagaaa aaacaagaaa
      121 ctttttatgc accttgttcc ggaaaaatca tttccatcac agaagtaaat gatcctgtct
      181 tttcacaaaa attactaggt gatggttttg ccgtcatacc tgatggttca aaaatttatg
      241 ctccattggc tggtcgagta acaaatatat ttcctactaa acatgctatt aatataaaaa
      301 gcaactcagg cattgattat ttgattcata ttggaattga tacagttgaa ttacaaggag
      361 agcctttttc gatttgtgtt caagaaaatg atgaggttac tcctgaaacc tcgttggttg
      421 atgtggattt tgacaaaata ataaaatctg gtaaagatac ttctgttata gttgtttttc
      481 cggagaaaaa tcagttcaat gatttaataa tagataatgg tcgaattgct catgggaatt
      541 catgtggaaa a
//
LOCUS       DAFLVO010000246          534 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.265, whole genome shotgun sequence.
ACCESSION   DAFLVO010000246 DAFLVO010000000
VERSION     DAFLVO010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.265"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..>534
                     /locus_tag="L1U99_003127"
     CDS             <1..>534
                     /locus_tag="L1U99_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HBN1213586.1"
                     /translation="DGFKACTDPRQAAYAFERNYERPAATHPERQDYAVNWYNKFKDL
                     KPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSGYLGGCGMGAGTKYGLTHVIGNT
                     SAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINWARGGQVGSWFADGTYGHTGVIR
                     GLANGRMQTYEQNTELG"
BASE COUNT          163 a           80 c          137 g          154 t
ORIGIN      
        1 tgatggattt aaggcctgta ctgatccaag acaagcagca tatgcttttg aacgaaacta
       61 tgaacgtccg gcagcgacac atcctgaacg tcaagattat gcagttaact ggtataacaa
      121 atttaaagat ttaaaaccag gaggagctac tggagaagca ggactaaaac atttagagtc
      181 tttgattgga caacgaattg gcaatggtca gtgttatggc ttgtctgcag aatattcagg
      241 atatctgggt ggttgtggca tgggtgctgg aacaaaatat ggtttaactc atgtgatagg
      301 aaatacttct gcagcatctg atattggtat tgcctatgat tggtctgctg ttggttggaa
      361 agtgattcaa aaccctagat atgatcaatt agtagttggt gcaattatta attgggcaag
      421 aggtggacaa gtgggttcat ggtttgcaga tggaacttat ggacatactg gcgttatccg
      481 aggcttagct aatggtcgta tgcaaactta tgaacaaaac acagagttag gtat
//
LOCUS       DAFLVO010000247          532 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.266, whole genome shotgun sequence.
ACCESSION   DAFLVO010000247 DAFLVO010000000
VERSION     DAFLVO010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..532
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.266"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..>532
                     /locus_tag="L1U99_003128"
     CDS             <1..>532
                     /locus_tag="L1U99_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBN1213587.1"
                     /translation="CVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLA
                     YTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYF
                     YGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHKIHEKL
                     ALKGITISVPPRKNMD"
BASE COUNT          176 a          102 c           94 g          160 t
ORIGIN      
        1 cttgtgttat atggggcata attaatggct atactagcca aagagccacg tatagagcgg
       61 tttgttccgt cttatttcct aatggtgact ttcctagtag gagtcgattc actcgcttaa
      121 gttcaaactt agcttacact atcaagatta ttcgatactt tttcatcaag aagctcacca
      181 aaggtgaact agtcggaatt atagatagtt ttcctagtcc attatgtaaa ccagttagaa
      241 atagacaagc aaaactattg aatcaaatag ccaaagttgg ctataactca acaaaaaaat
      301 cttattttta tggtcttaaa attcatatga tcgttactaa gactggcttt ccgattactt
      361 actcaatcac gaatccaggt gtccatgacg tgaaagtgtt agagacttta tcggaagaag
      421 cgaatcttcc caatatccta ggggacaaag gatatattag ccataaaatc catgaaaagc
      481 ttgcccttaa gggcattact atatccgttc cgccacgtaa aaacatggat aa
//
LOCUS       DAFLVO010000248          517 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.267, whole genome shotgun sequence.
ACCESSION   DAFLVO010000248 DAFLVO010000000
VERSION     DAFLVO010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.267"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
BASE COUNT          172 a           77 c           86 g          182 t
ORIGIN      
        1 tgctatgtat tatactgcat ctgctcaaat tgattttctt ttcatgctta ccatgtatct
       61 agttttccat caagtaattt ttagatatgt attgaggaat aaatagcaaa tttgcttgat
      121 ataagctcga attaggtgct ttgtaatgtg ttaggataaa ttatacaaga aaatgtcaaa
      181 agctctcaga acgcttctga gagcttttta tcggtaggct tgtttaacgt gatcttgaaa
      241 gatacccttt tgatgtttct ctcgatccct gcatcgctaa ttactaagtg ttcttcaagt
      301 gtgatgtagg tatataaatt aagcatcaaa atggtgtaga taagcaaaaa actccctaaa
      361 actaagtgtt gattataaaa atctgactta taaaaaagaa ctgagaatgt tagtgttgct
      421 tcccaaaaaa gaaacaaaat tttgtatttc caaagatagt ggatcaagcg ctgtgcttta
      481 ctcatctcaa ataatttata ataacctgct aattgat
//
LOCUS       DAFLVO010000249          514 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.268, whole genome shotgun sequence.
ACCESSION   DAFLVO010000249 DAFLVO010000000
VERSION     DAFLVO010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.268"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(107..>514)
                     /locus_tag="L1U99_003129"
     CDS             complement(107..>514)
                     /locus_tag="L1U99_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HBN1213588.1"
                     /translation="GTPENHFSNQISLNVYSRGMGGLGLPGDLSSVSRFVKATFTKMN
                     AASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSCCNVDKGIYYYRTYED
                     SQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
BASE COUNT          162 a          103 c           78 g          171 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgagacacg acctaaagat cgtgtctaat
       61 tatgactgta tcagaaaata tgataccaaa cggatctatt cattaattaa ttgacatagt
      121 ttatctgttg ctcttttatg actggataac tgaccaattc atgacgatcc aagtcttctt
      181 tattcatatt tacagcagta atttgactgt cttcatacgt acgataataa taaatccctt
      241 tatcaacgtt acagcaagaa gaataaatcg tatattcgta ttttccttct ccagtatcgc
      301 atactccttt ttgttgctcg actgagccta gtatatgaaa aaattgactg atactttcag
      361 attctgaatc acctgatgca gcattcattt tagtaaatgt ggcttttaca aatcgagaaa
      421 cagaagagag atctccaggt aagcccaatc ctcccatccc acgactataa acattcaagc
      481 tgatctggtt tgaaaaatga ttttctggtg ttcc
//
LOCUS       DAFLVO010000250          487 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.270, whole genome shotgun sequence.
ACCESSION   DAFLVO010000250 DAFLVO010000000
VERSION     DAFLVO010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.270"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..317
                     /locus_tag="L1U99_003130"
     CDS             <1..317
                     /locus_tag="L1U99_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213589.1"
                     /translation="WKAIEGSLVTQRIKELPDCLEKDHLFQIREMLKKEQFDPDQFLV
                     VEYPTIGVYCCNHINDGKYFIIQEYGGQLTPFYTTWEMSEEGINNFPCESIEDSISHT
                     EC"
BASE COUNT          182 a           60 c           91 g          154 t
ORIGIN      
        1 aatggaaagc gatagagggg tcattagtaa cgcaaagaat aaaggaatta cctgattgct
       61 tagagaagga tcatttgttt caaatacgag aaatgttgaa aaaagaacag tttgatccag
      121 accaattttt agtagtcgag tatccaacta ttggagtgta ctgttgtaac catatcaatg
      181 atggaaaata ttttattatt caggagtatg gaggacagtt aactcctttc tatactacat
      241 gggaaatgag tgaagaagga atcaataatt ttccatgtga aagcatcgaa gattcaattt
      301 cacacaccga atgttaattg attataacta taaaaaagga ttgaacatta tgttcaatcc
      361 ttttttcaat gaaatgtttt ccgccatttc attgtttggt gcgatttcta ttttattata
      421 tcaaaataaa gagagattct aaagaaagaa gagggaaata tataaatcaa gcgacagtat
      481 atttatt
//
LOCUS       DAFLVO010000251          485 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.271, whole genome shotgun sequence.
ACCESSION   DAFLVO010000251 DAFLVO010000000
VERSION     DAFLVO010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.271"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
BASE COUNT          160 a           96 c           56 g          173 t
ORIGIN      
        1 atgctaaatc actctacaat aacggcgaaa gcacaaaaaa taaaaaaatt attacgttat
       61 taaaaaaaca gatgaaagat caggttttat tagatctcat tctttcatca cttgaaggga
      121 tttaatgaac tactttttcc tctttgtcgt ttttatatat tcgtattcct tcaaacagta
      181 ggatagcctc tttcaatgct tgatatttga actgtccgtt acttaaaaat ttagatgtgc
      241 cgccctcttc ctagaacata ttctttttta ctttttcatt aattgacaga ccaatcgaac
      301 gaaactgtaa atttcgatag gataatgatt ggtcaaactc attcattttc aagacatctc
      361 gattcatatt caagatagga atctttttat caacatcact ttattcgtat tttcctctac
      421 cataaaagct tcacgctcca caaaattgtt ttatacacta ctattcagcc cattcaacga
      481 ccaat
//
LOCUS       DAFLVO010000252          479 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.272, whole genome shotgun sequence.
ACCESSION   DAFLVO010000252 DAFLVO010000000
VERSION     DAFLVO010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.272"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            7..>479
                     /locus_tag="L1U99_003131"
     CDS             7..>479
                     /locus_tag="L1U99_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HBN1213590.1"
                     /translation="MQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDYEKYDRTGF
                     NSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLETTIIHLFEK
                     GVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAIFMDAT"
BASE COUNT          174 a           87 c           80 g          138 t
ORIGIN      
        1 gaaattgtgc aaactctagt cactaaaggc gatttaaatg aattattccg ttcgcactta
       61 gaaaaagcga taaacacact cctacggact gaattaacgg cttttttaga ttacgaaaaa
      121 tatgatcgca ctggttttaa ttcaggtaat tcgagaaacg gttcttactt tcgatcaatc
      181 aaaaccgaat atggtgaatt aacattggaa atacctagag atcgtaatgg tgagtttaaa
      241 caacaaactt taccagccta caaaagaaca aacgatacat tggaaaccac tattatccat
      301 ttattcgaaa aaggtgttac gatgtctgaa attgctgatt tgatcgaaaa aatgtacggt
      361 catcactata ctccacaaac catgtccaac atgactaaag ttctgactga agaagtaaat
      421 gcctttaaat ccagagcctt aaatgataag tatgtcgcta tttttatgga cgctactta
//
LOCUS       DAFLVO010000253          476 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.273, whole genome shotgun sequence.
ACCESSION   DAFLVO010000253 DAFLVO010000000
VERSION     DAFLVO010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.273"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            22..>476
                     /locus_tag="L1U99_003132"
     CDS             22..>476
                     /locus_tag="L1U99_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1213591.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIEKRSTEGWTPDVIIGRAERTFS
                     CSVSTLYRRFKTGEFNVLHLPMQGKRKPNGYKEKRGKQAFKRNISERKK"
BASE COUNT          178 a           87 c           95 g          116 t
ORIGIN      
        1 atacaaggag agtgaacata aatgacttat acccatctta caccaaacga gcttgtaatg
       61 atagaagcat attttcatca agaaactccg gttgctatcg ttgcgaagca gcttaaacgt
      121 ggacgccaaa caatttacaa tgtctataac tttctcaaat gtggtggaac agcacttgaa
      181 tactttgaac aatacaaaga aaataagcga cgttgtggga gaaccgaaat catttttcct
      241 gctgaggaaa aagaatacat tgaaaaaaga tcaactgaag gttggacccc agacgtcatt
      301 attggccgtg cagagcgaac cttctcttgt tcagtaagta ccctctatcg ccggtttaag
      361 acgggagaat tcaatgtttt acatttaccg atgcaaggaa aacgaaaacc aaatggttat
      421 aaggaaaaac gtggaaaaca ggcattcaaa agaaatattt ctgaacgtaa aaaaga
//
LOCUS       DAFLVO010000254          469 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.274, whole genome shotgun sequence.
ACCESSION   DAFLVO010000254 DAFLVO010000000
VERSION     DAFLVO010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.274"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..>469
                     /locus_tag="L1U99_003133"
     CDS             <1..>469
                     /locus_tag="L1U99_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213592.1"
                     /translation="GEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKWPEEA
                     TQPITADDTEFVSSATKLDDKSDADKYNPEGQKVTTELNKEPDAFEGIKNKEDLPKDT
                     KYTWKEKVDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
BASE COUNT          191 a           69 c          111 g           98 t
ORIGIN      
        1 caggagaagg aacaagtatt gaaagtggaa caacagtctt tgcagtgaaa gacggcgtaa
       61 gcttaccaga agataaactt ccagtgttga aagcaaaaga tggttataca gatgcgaaat
      121 ggccagagga agcaactcaa ccaattacag cagatgatac agaatttgta tcaagtgcaa
      181 caaaactgga tgataaatct gacgctgaca aatataatcc tgaaggtcaa aaagtgacta
      241 cagaattgaa taaggaacca gacgcatttg agggaattaa gaacaaagaa gatttaccaa
      301 aagatactaa gtatacttgg aaagaaaaag tagatgttag cgcagctgga aataaaaaag
      361 ggactgttgt agtgacatat ccagatggat catctgatga agttgaagta gatgttacag
      421 tgacagacaa tcgttctgac gccgataaat atgagccaac agtagaagg
//
LOCUS       DAFLVO010000255          460 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.276, whole genome shotgun sequence.
ACCESSION   DAFLVO010000255 DAFLVO010000000
VERSION     DAFLVO010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.276"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(20..91)
                     /locus_tag="L1U99_003134"
     tRNA            complement(20..91)
                     /locus_tag="L1U99_003134"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56..58),aa:Glu,seq:ttc)
     gene            complement(113..200)
                     /locus_tag="L1U99_003135"
     tRNA            complement(113..200)
                     /locus_tag="L1U99_003135"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(164..166),aa:Ser,seq:gct)
     gene            complement(225..298)
                     /locus_tag="L1U99_003136"
     tRNA            complement(225..298)
                     /locus_tag="L1U99_003136"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(262..264),aa:Ile,seq:gat)
     gene            complement(312..382)
                     /locus_tag="L1U99_003137"
     tRNA            complement(312..382)
                     /locus_tag="L1U99_003137"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(348..350),aa:Gly,seq:tcc)
     gene            complement(384..459)
                     /locus_tag="L1U99_003138"
     tRNA            complement(384..459)
                     /locus_tag="L1U99_003138"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(424..426),aa:Asp,seq:gtc)
BASE COUNT          132 a          128 c          108 g           92 t
ORIGIN      
        1 taaaactata ttaaattaat gacccgtacg ggattcgaac ccgtgttacc gccgtgaaag
       61 ggcggtgtct taaccgcttg accaacgggc caggtaaaac aaaatattga aacggagaag
      121 gagggatttg aaccctcgcg ccggtttccc gacctacacc cttagcaggg gcgcctcttc
      181 agccacttga gtacttcccc aaaaccaata agattttgta ctaatgggcc taaatggact
      241 cgaaccatcg acctcacgct tatcaggcgt gcgctctaac cagctgagct ataggcccat
      301 aaaaaactaa aagcgggtga cgagaatcga actcgcgaca acagcttgga aggctgtggt
      361 tttaccacta aactacaccc gcatggcggt tccgacggga atcgaacccg cgatctcctg
      421 cgtgacaggc aggcatgtta acccctacac cacggaacca
//
LOCUS       DAFLVO010000256          437 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.279, whole genome shotgun sequence.
ACCESSION   DAFLVO010000256 DAFLVO010000000
VERSION     DAFLVO010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.279"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..>437
                     /locus_tag="L1U99_003139"
     CDS             <1..>437
                     /locus_tag="L1U99_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBN1213593.1"
                     /translation="PIENESDLEEIVQEEFIRNRKAYGTRKLKKCLAKRGLQLSRRRI
                     GRIMKRRGLTSTYTIAHFKGQRTACNEAKTANVLDRTFTQEQPLEAIVTDLTYVRVGK
                     KWHYICLILDLFNREIIGYSCGEKKDASLVKEAFGRIPYSLTDV"
BASE COUNT          136 a           82 c          105 g          114 t
ORIGIN      
        1 ccgatcgaaa atgagtccga cttagaagag atcgttcagg aagagtttat tcgaaaccga
       61 aaggcttacg gtacccgaaa attgaagaag tgtttagcaa agcgtgggct tcaactcagt
      121 cggcgccgaa tcggtcgaat catgaaacgc cgcggattga catctaccta tacgatcgct
      181 cattttaaag ggcaacgaac agcttgtaat gaagcgaaaa cagcgaatgt attagatcgg
      241 acctttacac aagaacagcc attggaagcc atcgttacgg atcttactta tgttcgcgtg
      301 gggaaaaagt ggcattatat ctgcttaata cttgatttgt ttaatcgaga aattattggt
      361 tattcctgtg gtgagaagaa agatgcctca ttggtaaaag aagcctttgg acggataccg
      421 tattctttaa cagacgt
//
LOCUS       DAFLVO010000257          413 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.284, whole genome shotgun sequence.
ACCESSION   DAFLVO010000257 DAFLVO010000000
VERSION     DAFLVO010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.284"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..390
                     /locus_tag="L1U99_003140"
     CDS             <1..390
                     /locus_tag="L1U99_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1213594.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          161 a           74 c           65 g          113 t
ORIGIN      
        1 aaagaccgaa aagaaatctg tgatgacttt aaggctgttt atcaagctaa ctcaaaagaa
       61 gaagcgaata ccttcttatc cggcatgatt gagaaatgga agaaaaacta tcctaaagtg
      121 acgcagtcac tcatagaaaa ccaagactta ttaacttttt atgattttcc acctagcatt
      181 cgtagaacca tttactcaac caatctaatc gagtctttca ataagcaaat taaaagatac
      241 agccgtagaa aagagcagtt tcaaaatgaa gaatcactag aacgctttct agtcagcatt
      301 tttgatacat acaatcaaaa atttctaaac agaagccata aaggttttca acaggtaacc
      361 gatacattag tttcaatgtt tactgagtaa ctaattattt tgcaggagga caa
//
LOCUS       DAFLVO010000258          396 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.287, whole genome shotgun sequence.
ACCESSION   DAFLVO010000258 DAFLVO010000000
VERSION     DAFLVO010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.287"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(91..>396)
                     /locus_tag="L1U99_003141"
     CDS             complement(91..>396)
                     /locus_tag="L1U99_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1213595.1"
                     /translation="TIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQF
                     ETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          107 a           95 c           78 g          116 t
ORIGIN      
        1 ttgtgaatgc tgcggtgtta tggctacgat tgcccttgac aatgagcatc ctcggatctg
       61 attttctccg gcagaagcac aatcattcaa ttacgctgcc tctccagagg tatcagatcc
      121 gcgctcatta tcaaggattc gcttcgccaa tctctgttgt cgaatttgga tcggtgtttc
      181 atacgccaac gtgccatgta agcgtagata gttccaccaa tgcacataat caaacaattc
      241 tagacgtagc tgtgccagtg tctcaaattg gtattgatgc acgaattcta ctttgacaga
      301 tttataggtt gattccacaa cggcattatc atacggacaa cccttcctac tcaatgaacg
      361 agtaattcca aaaccattca gaatctcatg aatggt
//
LOCUS       DAFLVO010000259          375 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.289, whole genome shotgun sequence.
ACCESSION   DAFLVO010000259 DAFLVO010000000
VERSION     DAFLVO010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.289"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..>375)
                     /locus_tag="L1U99_003142"
     CDS             complement(<1..>375)
                     /locus_tag="L1U99_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213596.1"
                     /translation="PYQPNLLDDPYWLGKAPLGENIANKSVTFPIKSSAYSLYQANME
                     EEFVLGQTYTITMKATKPPIQTFIVYNEDSGDYRYGNLEPVEGLVDTWGLTFTPQKVG
                     VNYPKRLTIIQYPQSTTGACQID"
BASE COUNT          100 a           73 c           80 g          122 t
ORIGIN      
        1 gtcaatttga catgcacctg ttgttgattg gggatactgg ataatagtta accgtttggg
       61 gtagttaact ccaaccttct gcggtgtaaa agtcagaccc catgtatcaa ctaacccttc
      121 tactggctct aagttaccat atctataatc tccactatcc tcgttgtaaa caatgaacgt
      181 ttggataggt ggtttggttg ccttcatggt aattgtatag gtttgaccta aaacaaattc
      241 ttcttccatg ttagcttggt ataggctgta ggcgctagat ttgattggaa acgtaacaga
      301 cttattagca atattctcac ccaaaggcgc tttacctagc cagtaagggt catcaagtaa
      361 gtttggctga tatgg
//
LOCUS       DAFLVO010000260          375 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.290, whole genome shotgun sequence.
ACCESSION   DAFLVO010000260 DAFLVO010000000
VERSION     DAFLVO010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.290"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..132)
                     /locus_tag="L1U99_003143"
     CDS             complement(<1..132)
                     /locus_tag="L1U99_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBN1213597.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          132 a           69 c           76 g           98 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaat
//
LOCUS       DAFLVO010000261          321 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.305, whole genome shotgun sequence.
ACCESSION   DAFLVO010000261 DAFLVO010000000
VERSION     DAFLVO010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.305"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(69..321)
                     /locus_tag="L1U99_003144"
                     /pseudo
     CDS             complement(69..321)
                     /locus_tag="L1U99_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT           79 a           78 c           51 g          113 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat g
//
LOCUS       DAFLVO010000262          305 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.308, whole genome shotgun sequence.
ACCESSION   DAFLVO010000262 DAFLVO010000000
VERSION     DAFLVO010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.308"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="L1U99_003145"
     CDS             complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="L1U99_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HBN1213598.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
BASE COUNT           95 a           45 c           50 g          115 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgtt
//
LOCUS       DAFLVO010000263          299 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.309, whole genome shotgun sequence.
ACCESSION   DAFLVO010000263 DAFLVO010000000
VERSION     DAFLVO010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.309"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..>299
                     /locus_tag="L1U99_003146"
     CDS             <1..>299
                     /locus_tag="L1U99_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1213599.1"
                     /translation="TIVGIHHKSAVITLVERLSKAIIALKPEGRKAVDIENSINEWLQ
                     SVPKNLFKSITFDCGKEFSNWKSISNTNDIDIYFADPGTPSQRGLNEHSNGLLRK"
BASE COUNT          102 a           63 c           54 g           80 t
ORIGIN      
        1 acgattgtcg gcatccacca taaaagtgcc gtcatcacac tcgttgagcg actttcaaaa
       61 gccattatcg ccttgaaacc agaaggccgt aaggcagttg atattgaaaa ttcgattaat
      121 gaatggcttc aatccgtacc caaaaatctt ttcaaatcaa ttacctttga ttgtggaaaa
      181 gaattctcta attggaaaag tattagtaat acgaatgata ttgatattta tttcgcagac
      241 ccaggaacgc cttcccaacg gggattaaat gaacattcaa acggactcct ccgaaaaga
//
LOCUS       DAFLVO010000264          283 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.313, whole genome shotgun sequence.
ACCESSION   DAFLVO010000264 DAFLVO010000000
VERSION     DAFLVO010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..283
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.313"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            1..283
                     /locus_tag="L1U99_003147"
                     /pseudo
     CDS             1..283
                     /locus_tag="L1U99_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          109 a           57 c           56 g           61 t
ORIGIN      
        1 aacaaatcgt cgatctctat ctcgctggta agcctcgcgc agaaattatt cgagagtatg
       61 agcttacgcc ttcttctttc gataaatgga tgaagcaagc acaatcaacg ggctcattca
      121 aagaaagaga caacttaaca ccagaacaag cagaattgat cgcactaaga aagaaaaata
      181 agcaactcga aatggagaat gatattttaa agcaagcggc gctgatattc ggacgaaaag
      241 acaagtaatt gatgccaaca agcataaata ttccatatca gcg
//
LOCUS       DAFLVO010000265          282 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.315, whole genome shotgun sequence.
ACCESSION   DAFLVO010000265 DAFLVO010000000
VERSION     DAFLVO010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.315"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..>282
                     /locus_tag="L1U99_003148"
     CDS             <1..>282
                     /locus_tag="L1U99_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HBN1213600.1"
                     /translation="QSKRLFPEINCVVADAGYKTPKFVHFLTHLNLRPCLPYSRPKGK
                     KGLLSKNEFLYDEYFDCYICPQDQMLAFSTVTREGYREYKSNPKECVNC"
BASE COUNT           84 a           52 c           56 g           90 t
ORIGIN      
        1 aacaatcgaa gagacttttt cctgaaatca attgtgttgt cgctgatgct gggtataaga
       61 cacctaagtt tgttcacttt ttgactcatt tgaaccttcg accttgtttg ccttattcaa
      121 ggcccaaagg gaaaaagggg ctattatcaa aaaatgagtt tctctatgac gagtattttg
      181 attgttatat ttgtccgcaa gatcaaatgc tcgctttttc aacggttact cgagaagggt
      241 accgagaata caaatccaat ccaaaagaat gtgtgaactg tc
//
LOCUS       DAFLVO010000266          267 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.321, whole genome shotgun sequence.
ACCESSION   DAFLVO010000266 DAFLVO010000000
VERSION     DAFLVO010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..267
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.321"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            51..>267
                     /locus_tag="L1U99_003149"
     CDS             51..>267
                     /locus_tag="L1U99_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1213601.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAE"
BASE COUNT          112 a           44 c           45 g           66 t
ORIGIN      
        1 taatttttaa tagaaaacac tattaaagag aaaaaagaga ggtaaatcaa atgaaaaaat
       61 ctttaaaact tgcatcagca gttatattaa tgtcccaact ccttatagca acacctttcc
      121 atgtgttggc aagcgaaaat tcaacataca aaattgcaaa agaaagaacc gagacgactg
      181 aaatgagtaa ttccgatgta acagcagaga gtagtgaact tttgacaact tcatcaagtg
      241 aaagtagtac gacttcaaat gccgagt
//
LOCUS       DAFLVO010000267          267 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.322, whole genome shotgun sequence.
ACCESSION   DAFLVO010000267 DAFLVO010000000
VERSION     DAFLVO010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..267
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.322"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(35..>267)
                     /locus_tag="L1U99_003150"
     CDS             complement(35..>267)
                     /locus_tag="L1U99_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1213602.1"
                     /translation="LKNLPETLDAQLRTKLQNLLTYEEGIYNAMIYPYSNGKIEAKIP
                     HIKTLKRLSYGFKSFENMKIRIFLINQLIQVK"
BASE COUNT           78 a           39 c           47 g          103 t
ORIGIN      
        1 tagaaggact gaccttctgt ctcagatttt tttgttattt cacttgaatc aattgattga
       61 tcaaaaaaat cctgattttc atgttctcaa atgatttaaa tccataagat aatcgtttca
      121 gtgtcttgat atggggaatc ttggcctcta ttttgccatt agaatacggg taaatcatag
      181 cattgtaaat accttcttca tacgttaaaa ggttttgaag tttcgtgcga agttgtgcat
      241 caagtgtttc aggaagattt tttaata
//
LOCUS       DAFLVO010000268          253 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.denovo.329, whole genome shotgun sequence.
ACCESSION   DAFLVO010000268 DAFLVO010000000
VERSION     DAFLVO010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.denovo.329"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            28..>253
                     /locus_tag="L1U99_003151"
     CDS             28..>253
                     /locus_tag="L1U99_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HBN1213603.1"
                     /translation="MLGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWD
                     GKVYVQNLFNAAGIKEPITSLDAQVRLLIWT"
BASE COUNT           80 a           40 c           58 g           75 t
ORIGIN      
        1 ggatttacga aacaatctgc atgtggaata ttggggaaca ttcaacaaga aacaggagga
       61 acttttgatc ctgatactgt tcaaataggt ggaccagcat acggattagt tcagtgggat
      121 ggttcttcat atcctcttgt tggtccagca acatgggatg gaaaagttta tgttcaaaac
      181 ttatttaatg ctgcaggtat taaagaacca ataacgagct tagatgcaca agttcgattg
      241 cttatttgga cat
//
LOCUS       DAFLVO010000269        13213 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.guided.077, whole genome shotgun sequence.
ACCESSION   DAFLVO010000269 DAFLVO010000000
VERSION     DAFLVO010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.guided.077"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(204..2162)
                     /locus_tag="L1U99_003152"
     CDS             complement(204..2162)
                     /locus_tag="L1U99_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1213604.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(2159..3031)
                     /locus_tag="L1U99_003153"
     CDS             complement(2159..3031)
                     /locus_tag="L1U99_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1213605.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(3373..4245)
                     /locus_tag="L1U99_003154"
     CDS             complement(3373..4245)
                     /locus_tag="L1U99_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1213606.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            4373..4942
                     /locus_tag="L1U99_003155"
     CDS             4373..4942
                     /locus_tag="L1U99_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBN1213607.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            5009..5746
                     /locus_tag="L1U99_003156"
     CDS             5009..5746
                     /locus_tag="L1U99_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1213608.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            5977..7245
                     /locus_tag="L1U99_003157"
     CDS             5977..7245
                     /locus_tag="L1U99_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBN1213609.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            7732..8196
                     /locus_tag="L1U99_003158"
     CDS             7732..8196
                     /locus_tag="L1U99_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1213610.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            8180..8809
                     /locus_tag="L1U99_003159"
     CDS             8180..8809
                     /locus_tag="L1U99_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBN1213611.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            9163..10641
                     /gene="msr(C)"
                     /locus_tag="L1U99_003160"
     CDS             9163..10641
                     /gene="msr(C)"
                     /locus_tag="L1U99_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBN1213612.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            10688..11134
                     /locus_tag="L1U99_003161"
     CDS             10688..11134
                     /locus_tag="L1U99_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBN1213613.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(11333..11848)
                     /locus_tag="L1U99_003162"
     CDS             complement(11333..11848)
                     /locus_tag="L1U99_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBN1213614.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            11965..13167
                     /locus_tag="L1U99_003163"
     CDS             11965..13167
                     /locus_tag="L1U99_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1213615.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         4116 a         2424 c         2708 g         3965 t
ORIGIN      
        1 agaggttgta aaaaagctgt tctgcatcaa gtaataagaa gagtcaaata aaaaatagct
       61 cttcatatgt tacgtttggc tggacttatt accgcggagt tggcaggaga acgccgtttt
      121 tattcggaaa aaggagctga gacaagattt ttgtctcagc tcctgtttgt ttatcgataa
      181 aaaagtctgg ggaagacgat ggctcaggct ttgttggaaa cagagccgat tttatcattt
      241 gcttttacat cacgtgcggg ttcgatttct aagctttgga ctttgtcgcc atttgtgaat
      301 acaacgacca tatccgtgtt tttgcctgca gattgaatag cggcaagatc aactaaagca
      361 atcaattgac ctcttgcgac tttttgacct tcttttacat ataaagtgaa tggttcgcct
      421 tttaagtcaa cagtgttgat gcccatatga agcaagactt cgataccagc atctgtttgg
      481 attccgacag catgtttcgt tgggaaaatg tttgtgatcg taccagcgat tggagagaag
      541 atttctccat tttctggtaa tacagcatag ccgtcaccca tcattttttc cgcgaataca
      601 tcatctgaaa cttcagtgat tggaatcagt ttcccatttg cgatagcgta aatatcttgt
      661 tcgatcgttc caccggcaaa tgtttctgtt ttaaccacgg tgtttgtttg tgcaggtcgt
      721 gttgcagcac caccatgtag ttttgccatc tcatctgcaa cgaattgtac ttctgtacct
      781 acgatgactt gcgcattttt tccgtcgatg atcttcatac caggtacgcc agtggctttg
      841 attttatttt gatcgatcag gcctgtatct ttgacttgca aacgaaggcg tgtagtacag
      901 ttatcgatcg aagttacatt gtcggctccg cctaatgcag cgtagatttt gcttgcttgt
      961 gccgcatatt tattgtctga attagtcgtt gcagtatcgt catctgaaag atctgcttcc
     1021 tcgcggccag gagtcatcag atggaatttt ttgatagcaa agttaaagcc aaagtagtaa
     1081 atcactgctg ttactaatcc ttggacgatc aacatcaatg gctgattcgc aatcggattt
     1141 ttcaaagata ggaagtaatc gacaaatccg gcactaaagg caaatcctgc tgtccaatgg
     1201 aagaatgcac tcactgctaa agaaatccca gtgaaaattg catgcaagac atataatggc
     1261 caagcaacga acataaatga gaattcaagt ggttctgtta caccagtaaa gaatgaagca
     1321 aaagctgctg ctaacatcaa ggaagctgtt tttgctttgt tttctggacg tgcatttctg
     1381 taaatagcat atgctcctgc tggaagcccg aacatcatga ttgggaaaaa tccagcttga
     1441 tacattcctg ttacgccttt tgttccttca gaagccaaaa atttaccaat atcattgatt
     1501 cctgctacgt caaaccagaa cacggagttc attgcttgat gcaatcctgt agggatcagt
     1561 aaacggttga agaagccata aagacctgca ccaccccagc ctaaactcaa aatgaattta
     1621 gcaaaagaaa ctaaagcaga gtaaaccgga ggccatacga gcagtagcac tgcactgatc
     1681 agcaacatga caaaggcagc caagattggc actagacgct tgccgctaaa gaaagataaa
     1741 gccatcggta attttgcttc gtggaaacga ttataaagag ctgccgcaat caatccggca
     1801 ataataccaa taaatacgtt actgatctga gcaaaagatg gatcaactga ttctggtttg
     1861 atattcaata aagtagctac tgaatcagtt tttaaaacat ttactggaac ttcaaatgcg
     1921 accaaacctg ccaaggcagc agcacctgat ttgtccactg acatccctag tgctaaccca
     1981 acggcaaaca gcaaaggtaa ttgacctaaa actgcgttac cgccagcttg taaaaaatga
     2041 gcgacaatgt cgttactata agatgcccac cagtttccga tccctactag taaagcagca
     2101 gcaggtaaga ccgcaactgg aagttgaagg gaacgtccca ttcgttgtag atatgctttc
     2161 aatttttttc ctcctcatga ttgttaacat ttgtttgtac gattgcgctt cttaaacgct
     2221 cgatatggat ggccaagtaa cccagttctt ctttcgtgat cgcgagctgg tattctttgg
     2281 tcagcaacac acggattttt ttagaaatct tatagctttc tgggtatttt cgtttgacca
     2341 tttctacgat ttccgtgtct aaaacagcat attgttgcgc atgggttcgt tgtagaagca
     2401 gtcgtaaatg attcaccagt cttgaataat tcagtgaaaa tggttctgaa tggatatctg
     2461 tttccaattc tgattccact aaatggatga tgtcagatac aatcgtcact tcacggatac
     2521 tgcgatggtt attgttccga ccgcttcgtc cgctgtgaat atggattgcg atatatcctg
     2581 cttcgtcata agtatatgga atcccaagct cttttgtcag atactctact gcccattgag
     2641 caatactgaa ttcatcactg taaagcactt cgatttctct taaaagtttg ttgcggatga
     2701 cgataccgtt attaatgttc tccgcagaaa aagcaatgtg gtcggtcaaa gcgatcaata
     2761 catgttcatt caacttttcc atcaaaacag tttccgcatg atcaatgatc gtttctgctg
     2821 caaataaaaa gcgttcatca atctgattaa gtaaattttg caacttgatt tgaccttctg
     2881 gttccatgac aaatatccgt tcgacatcac gatcaaaaat caaatcattt ctttttctgt
     2941 caaatccaat cccttttcca atagctactt tttcctgtcc accgtcatct accaatactg
     3001 cattttgatt aaagatcttt ttgattttca tgcgcgcacc ctttttgaag atttggtttt
     3061 cacgtttgct agaccagttg attgcggcca aacaaaaata gacacgaaaa acctcctagg
     3121 gaaaccatgt tcctcagaga tttttcatgc ctagtatgat ctagtcacat gaaacgaatt
     3181 attgttaacg taatcaattt tatatagaca gttatgtttt gtcaattctt tttttataat
     3241 tatagtaatt tactggaatt atcagaaata aaaggaagga acaaattaag aaacttatgt
     3301 tatttaatca ttggatcttt tgcttaactt attcgttgtt aaaaagctga aagcgaagga
     3361 aaaaaactct acttaactgt atttctccgt taggacatct aaaaatttac gagcagcagg
     3421 agaaagaggc tggtcttttt tccaaatgag attcagtgaa gcttgtaatg gcggatcgag
     3481 tgggatgaat actttttccg tcccataagt attgatgatc ccatctagag ctaatgcacc
     3541 aaaagtcccg ttatcgacca tcaaagaagc attgtacaat aagttatatg ttccgacgat
     3601 cgataactga tctatgctga aacctagcca ttcagctagt tgactgtcca ctgacgtttg
     3661 ccgggaaatg atcaaaggaa cagttttcag ttcctgcgga tggatgactg tttgctttgc
     3721 taaaggatga ttccgatgta tcaaaagtcc ccaacgatct tgggctggca gtcgaaatga
     3781 ctggtatttt tgtttgtttg tcggttcgat tacgagtcca aaatcaagta atccgctatc
     3841 cagtttgtct atgatatcat ctgcattccc gctatataaa tgaaactgga tatcaggatg
     3901 cgccttgatc aacgaatgaa ggctatcaga aatgaaagag attgctttag tttcgcctcc
     3961 gccaatgtag atttctccag agatgattgc gtcatttgtt aaattgttcg ccgttttttc
     4021 taccaacgac aagatttctt ttccttttga ataaagatat cgaccagaat ccgtcaactg
     4081 tatctctcgg gagcctcgag tgaaaagtgt cacaccaagt tcttcttcta aatctttcag
     4141 ttgttttgag agagtaggtt gcgtgatatg cagagatttt gctgctcggc tgatattttt
     4201 ttctctagct actgctaaaa aatacgtcag tatacgaata tccatttttt ccctcctgtt
     4261 tttaaaaaag cataccacta agtatagtta aaaggaatag ttaagtatgt tttataagta
     4321 ttagacatca taagccgtcc gttataaagt aaggataaaa ggagggagca aaatgacaag
     4381 cctcatcgaa aaacaaatcg tcaataaaga gattcgagta acggatccgc tctttgaagt
     4441 gatccatcag atccaagcgg aaaacgaaga gcctttagca gcgctgaata ctgggtacca
     4501 tgaaccagca gatatccgca aacggctaga aaatatcatt agtgacaaag tagatgatac
     4561 ggtgactgtt ctgctgcctt tttatacaga tttcggcaaa catattagta tagggaaaaa
     4621 tgtctttatc aatcgtcaag tgatgttcgt tgacttaggt ggcatctgtt tagaagattc
     4681 agtattgatt ggtcctcgtg tcaacctcat cacggtgaac catctaaccg atccaaaaga
     4741 acgaagaggc ttgtcagtaa agccaatcca catcaagaaa aatgcttgga tcggagcagg
     4801 agcaactatt ctgccaggcg taacgattgg cgagaatgcc attgttgcag cgaatgcaac
     4861 tgttacgaaa gatgtcccag acaataccat cgttgcagga atccctgcca aaatcgtcaa
     4921 acctgtcgaa cggattattt gaacagtaag atgaaataag agatagtgag tataagcaag
     4981 agatttttca aaacaggagg agaatagaat gaatgattta tcagaaaaag tgattgtcat
     5041 catgggcgct tcaagcggaa tcggtgaagc aacaacgaag ctattagcag aaaaaggggc
     5101 taaactagtt atagctgcac gccgagaaga tcgcctaaaa gcaataaaag aatctttacc
     5161 agaagctgag ctatatattc aaacagcaga tgtaagagat tttgcacaag tccaagcagt
     5221 tatcgattta gcgatggaaa agttcggtcg aatcgatgta ttgtacaata atgcaggaat
     5281 catgccaacc gctccattag ttgaaggtca ccgtgatgaa tggcaaaata tgcttgatat
     5341 caacatcatg ggtgtgttaa atggaatttc cgccgtactt ccaatcatgg aaaaacaaaa
     5401 atctgggcat atcatttcaa ctgattctgt ggcgggacat gttgtttatc ctgattccgc
     5461 cgtttattgc ggaacaaaat ttgctgtccg tgcaatcatg gaaggattac gtcaagagca
     5521 acggcaaaat aacatcaaat ctacgatcat ctctccagga gctgttcaaa ctgaattata
     5581 tcaaaccatc agcgacaaaa aggctgctct tgaacttcat gaagcgcaaa aagaatgggg
     5641 attaacatct gaagatatag cttctgctgt agcatttgcg atagaaacgc cagaccggat
     5701 gtctgtcagc aacatgatta tccgtccgac gacacaggaa gtataatcca taacggataa
     5761 tatccagaga gaattacttg ttaaatagtt attcaaacga ccatcaattt aaggcgtgaa
     5821 tggagaagaa tattcttcat ttacgtcttt ttatgcagaa aaagcaaatt tattaaaaag
     5881 aaacaaatgt tatttaaata tggacattga cttgctttta cttttttagt tacactgtta
     5941 tttaggaaaa gtttcataat tcaaaggaga aaaaagatga aagcaaagaa tttattattt
     6001 agcgttattc ttttaggaaa tctagcagtt gccaacacaa cagtgctagc tgaagaatcg
     6061 acagaaactg tcgcaactca gacatcgagt tcttcagaaa caggaattga aaacgataca
     6121 gaaagtactt tgcagtcagc tactgtctca gaaaatacaa tttcaaccga agaaccaaca
     6181 actgaaacaa cagaacaaac acaaaccgaa gacagtacat cagcagaagc tcagaacaat
     6241 ccagagaatg cagaagaaat cacgaaccaa ttgacagatg ggcaaacatt gacacatacc
     6301 catcaagcag atttgtctga attcgaaaac tatactggct atgcttttta tgctcgctca
     6361 tctgctaatt ctcaacaagc gttcattgat agtattgcct caactgcaca aagtttggca
     6421 agtgccaatg acttatatgc atcagtcatg attgctcaag ccatcgttga aagtggctgg
     6481 gggaacagta ctttggcttc tgcccctaat tacaatctat ttgggattaa aggaagctat
     6541 aatggccaat ctgttacgat gcctacttcg gaatatgtga atgggcaatg gattacggtg
     6601 aatgccgctt ttagaaaata tccttcgtac aaagaatcat tgcaagataa cgtaacggta
     6661 ttgaagacga cttcttttca gccaggcgtt tactactatt ccggtgcatg gaaaagcaat
     6721 acgaactctt acaaagatgc tacggcttgg ctaacaggtc gttatgccac tgcgcctaat
     6781 tatggttcta cattgaacaa tgtaatcgaa acctataatc tgacacagta tgatacagca
     6841 ccaacttcaa cttctccgat gtatcgtctg tataaccgtc atacaggaga acatttatat
     6901 acattgaatg ccggagaaaa aaattatctg ccaactgtag gctgggaata tgaagggatt
     6961 gcttggcaag caccaaacag cggacaacct gtctaccgtt tatacaatcc ttacagtgga
     7021 gaccatcatt acacaatggc acaatctgag atcaactctt taacaaaaat cggttggcgt
     7081 tatgaaggtc taagttttta ttctggtggt tccaagccaa tttatcgact atttaatcca
     7141 aatgaaaaaa ctggtaccca tcactatacc ttgagtgcta aggaaagaga ttggctaaca
     7201 ccgatgggct ggagatatga aggaatagga ttttatggtt attaaaaaga ggtagtgaaa
     7261 aagctgccct gcatcaagta gtaagaacag ccaaacaaaa acagattttc atgttttttg
     7321 tttggttgaa cttattaccg cagatgcaag tttttgaaca ccgtttactc aaaaaaggtt
     7381 gtgacaacat cttgtcataa cttttttatt actgtttaag catactgatc caatttctaa
     7441 tattcgacgg gattcttgca aaaggcgatt tcggaaattt ttggcggtgt aaaattatct
     7501 actgcagaag agctatcttc tatagtttga taagaatcaa taatcttggt tttagcgttg
     7561 tgctttcttt atcatttttt ccgttcattc tacaaaaaat ttcttttctc tatacttttc
     7621 tattgagagc gtttttttta ttacacagct gattctttga cttttttctt tttttattct
     7681 attattgaca agtcaatcgt tgacgagtca attattagaa aggaggaaat tatgtcttta
     7741 gaagagatta gtcacctttt atatcaaatc aaattagccg atcaaaaaat cgtccagatc
     7801 tttgaagaaa atatcggtat aagtcttact agatacgaga tcatgatgag actgaaagaa
     7861 gaaaatccat tgctacaaag cagtttgcaa gaaaagttgc agattgatca aggagcagtt
     7921 actcgtcatc tgaaggtatt ggaagcaaat ggctatgttt cgcgtcagag aaatcctcag
     7981 aacaaccggg aagtgtatgt agcgctaaca gaaaaagccc agaagaaaat caagcattgt
     8041 gaaatggacc ataaagatac aggttccgtg ctatccccgg ctttcagcga tgtagaaatg
     8101 aaacaatttc taacactttt agataaattg aatacccaac tttgcaatat aacaacagaa
     8161 acgaaagagg ttaataataa tggaacaaaa aaatgatttt tcaacaatta tgactggtag
     8221 aagatccgtt cgcgtatatg atgaaacata caaaatccca cacgaagaaa tgctggaaat
     8281 gatcaaagaa gcgacgactg caccttcttc tgtcaatatg aaaccatggc gctttgtggt
     8341 cgctgaaagc gaggaagcaa aagaaatctt gcgtcctttg atccgtttca atacgagaca
     8401 aaatgatact tcttctgcaa tggtcatgat ttttggcgat atgcaatgtt acgaatatgg
     8461 cgaagaaatc tacaaccaag cttacgaatc agggaagatg ccaaaagaag tcagagatca
     8521 acaattagct gcgatcattc cttattacaa gagtttttca agagaagaaa tgaacgatgt
     8581 agtcaaagtc gattctagct tagcggctat gcaattcatg ttagttgcgc gtgatcatgg
     8641 ctatgaaaca aatccaattg gtggattcga agcagatcag ttggcagagg catttggttt
     8701 ggataaagac cgttatgttc cagttattat tttatcaata ggaaaagcgg tagaagaagg
     8761 ttacgagtct gttcgtttag caccagaaaa gatcactatg ttcgaataaa aggttttcag
     8821 ttactattca gtagctattg ctttttttga atcgtgtgtg gtaacctaat aaaaaaggag
     8881 gtcggaaaaa tgactgcatc gatgaaatta cgtttcgaac ttttgaataa caactaaata
     8941 aattcaaaag acatgtataa acaacaattt catggatgga gtatgtccat tttttcgaac
     9001 gacagtagaa taggtgaaag ctatgacaga tttggtgatt tagtcatagt tatttcgttc
     9061 agagtaggaa aagatgtgat gcagtttttt tgcaaacaga tttttctgct cttttttagt
     9121 atcgataatt gttgttttac atgaaatagg agtgtaaaac atatggaaaa tttagcagta
     9181 aatataacaa atctacaagt cagctttggc aaccagctag aactatctat tgattctctt
     9241 cgtgtctatc agcaagatcg tatagggatc ataggagaaa atggtgtcgg taaatcgact
     9301 ttgctcaaac taatagccgg tgaacttttt cccgatcatg ggaaaatcca aacagagatc
     9361 accttcaact acctgcctca attaacctat ctcgctgaag caaaggacct aaatttggaa
     9421 ttagccagtc atttccagtt aagactggaa gaaacttcag agcggaaatg gagcggaggg
     9481 gaagaacgaa agatcgagtt gatacgtctt ctttcttctt atgaacaagg gatgcttcta
     9541 gacgagccaa caacccatct agatagaaaa agtattgatc gactgattga agagcttcgt
     9601 tattattatg gtacgctggt ttttgttagt catgatcgct attttctaga tgagctagca
     9661 tcgaaaatct gggaagtaaa agacggagaa atccgagagt tttcggggaa ttatagtgcc
     9721 tatctcactc aaaaggaatt ggagaaaaag actcagctac gagaagcaga gtcgatcatg
     9781 aaagagaaaa aacgattgga aaaatcgatc caagaaaaga aaaaacaagc ggaaaagttg
     9841 gaaaaagtgt ccagtaaaaa gaaaaagcaa caaatcagac tggatcggtt gtcttcctct
     9901 aaacaaaaag acagtgtaca aaaagccatc caaaagaatg cgaaaacatt agagagaaga
     9961 ctccaaaaaa taggagaaac aaccaagccg cagcagatga aacaaatccg ttttccagta
    10021 ccaaaatctc ttgaactcca cagccgctat cccatcatgg gacaaaatgt ccaattggaa
    10081 agaagtggga gaacattact ggtaaatggt gattttcagt tttctttagg taaaaaaatc
    10141 gcgattgtcg gtgaaaatgg ttcaggtaag acaaccttat tagaacatat ccgcaaacaa
    10201 ggagaaggaa tccttctctc tccgaaagta agctttcaag tatatcagca aaagggttat
    10261 caaatgacat ctgaagaatc catcattcgt tttgtcatga gacaaacaga gttttcagaa
    10321 tcgcttgtcc gtagtttgct gaatcactta gggtttgctc aggaaacttt gacgaaaccg
    10381 ttatgtacat taagtggggg agaagcgacc cgtctgacga ttgctttgct ttttactaag
    10441 ccaagtaatg tgttgctgtt agatgaaccg actaatttta ttgatatggc aacgatcgaa
    10501 gctttagaga agctaatgca aatatatccg ggaacgattt tgtttacttc tcatgattct
    10561 tactttgtcg agcgtacggc tgatgaagtt tatgaaataa aagggcagaa aataaaaaaa
    10621 gtacttacga gaaattttta aatgtgctac gatgattttc gtgacaaatt taaaggagtg
    10681 gtacagattg cctacaaata aaaaagaagg aataattttt acaacaatga tgtgtttttt
    10741 gatggtcttg gggatgagcg cgtataattt atggctgcat caagatcttc atttatcaag
    10801 tttgttgatt ggtctagtgc ctggattcgt ggtggctttc attttggatg tcttcatcat
    10861 cggtgtgctg gcgaaaaaaa ttgcctttaa actaccagta aatccagaaa gcaaggtcca
    10921 aatgatctta actatttcat gcttgatggt tttaggaatg gtgacatgta tgtctttatt
    10981 cggtgtgatc atggaacaag gaatacctga tcaattattc tctgcttata tgaatgcttg
    11041 gaaaatgaat gtgattgccg ctttaccgtt gcagttgatc atcgttggcc cgctttcaag
    11101 aagtgtgcta aaagcaattc aaagtaatga atgatggaac actgttattt gaaaaaaggc
    11161 cttggcatgc tttttgtcat agtctcttga atgcagttct agaaaaatag tgatccgaac
    11221 gataggtttt ggcctgtcgt tcggatcgct ttttcttttc caactgtatt gctcttttat
    11281 tgaagataat ttgctcttca atagatattt ctagaaaggt tctgtttatc ccttactcaa
    11341 aaaactgctg catttgttct cttacttgct gacaccattg gagttcctgc tgacaaagca
    11401 taattctgcg ctggatcaca acataacgtc caaattcttg tttcttgtct agcgagaggt
    11461 cattcaattt tttttgattt ttttgcatga ttttgttcag ctgttgttct ctagtgaata
    11521 gcagtccagt agctgttgtt ttatcgagcg tcgaaaaagc atagattttt gctagaaatt
    11581 catctttttg cgtaggagcg ggagtttcct ctttgatcca ttcctctaca agagcacgtc
    11641 cttcatcagt caagtggtag atcttttttt gagagtgctc gtctttgtcc aaaacggtca
    11701 cataaccctg ctggtctaac ttggcaagcg ttgtatagat ctgactgtga tgggcttccc
    11761 aaaaaattgt gatcagctgc ttcaattcat acccagaacg tggtttggat aaaagcacgc
    11821 ataataatat ataggctaaa gtattcataa aaatcctacc tctcgtctta ttttctttat
    11881 tatatcacag taaagtttcc acgttttaca tgtgcatatt gacatgtaaa ataaatcatg
    11941 tatgatgcta atagagagaa agggatggaa atattggaga atcaaataga tatacaagaa
    12001 caaacaaatg aagaaacaaa ggggaaaagt tcagcgctag ttgtagcagc tacctgtatg
    12061 atcgctttta tgggagtggg tctagtagac ccaatcttaa aaacgattgc tgcacagtta
    12121 aacgctacgc cagctgaaac gaccctgtta tttactagtt acatgttagt cactggtgtg
    12181 gtgatgctat ttacaggttt cttatctagt cggatcggtt tgaaaaaaac attgatgaca
    12241 ggattgttta tcatcgttgt attcgctggt cttggcggat tatctgggaa tatcggaatg
    12301 ctgattgggt tacgtgccgg ctggggtgtc gggaatgctt tatttgtctc tactgcttta
    12361 gcaacgatcg tcagtatttt agttggtaac acagaaaaag caatcatgat gtatgaagca
    12421 gcacttggct gcggaatggc tgttggccct ctagtcggtg gggtcttggg cagtggttca
    12481 tggcgttatc cattttttgg ggtagcattt ttgatgtttt gcggttttat agccctagcg
    12541 gtacttttac ctgaaactga gaaaccaaag agaaaagtag gcctttggga aggtgtcaaa
    12601 gcgttaagca atcataaact tcgttcagtt ggactaatcg cattgttata taatttcgga
    12661 ttctttactt tacttgcgta tgcgccattt ttattgattg gctattctga attagaagtc
    12721 ggttttgtat tttttggctg gggtgtgctt ctggctattg cttcgatttt cgttgcaccg
    12781 gctcttgagc ggaagtttac gacttatcgg acaattttag cagcatttgt cttattcatt
    12841 atttgtttgc tgttattagg agctggaact tctatgccag tccttgtacc gatcagcatt
    12901 gtgttagcag gatttttcca aggaattatc aatacactgt tgacgacgat tgctatggaa
    12961 ataccaggtc tgcaacgaaa cgttgcttcg tccagctata gttttgtccg ctttttcggt
    13021 ggagctttag caccatttat tgcaggtgtg attggtgaac atattggtga aagctatgcg
    13081 ttttattttg caggtgccat tgttcttatc agtgtatgtt gtatcattta tcaccgtaat
    13141 tattttgcta caaatgaaga agaataagaa atcagaggtt gtgaaaaagc tgtcctgcat
    13201 caagtcataa gaa
//
LOCUS       DAFLVO010000270        12083 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.guided.082, whole genome shotgun sequence.
ACCESSION   DAFLVO010000270 DAFLVO010000000
VERSION     DAFLVO010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12083
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.guided.082"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..455
                     /locus_tag="L1U99_003164"
     CDS             <1..455
                     /locus_tag="L1U99_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBN1213616.1"
                     /translation="RAESYKQEFIKRDVTTNYFILPHRGNEQPGYLTYEEYLKKTGES
                     RGILELLREGQQGVTLRTFESMYFQKKLVTDNQAIAHYHFYRPENIFLLRERDLDELP
                     EFLHTPFKPILSELLEFYDAENWAKRFITNDSTIYEQYEYDLSSVENK"
     gene            complement(605..1546)
                     /locus_tag="L1U99_003165"
     CDS             complement(605..1546)
                     /locus_tag="L1U99_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBN1213617.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            1672..2793
                     /locus_tag="L1U99_003166"
     CDS             1672..2793
                     /locus_tag="L1U99_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBN1213618.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3051..4553
                     /gene="eat(A)"
                     /locus_tag="L1U99_003167"
     CDS             3051..4553
                     /gene="eat(A)"
                     /locus_tag="L1U99_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBN1213619.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            4581..5147
                     /locus_tag="L1U99_003168"
     CDS             4581..5147
                     /locus_tag="L1U99_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBN1213620.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            5358..6419
                     /locus_tag="L1U99_003169"
     CDS             5358..6419
                     /locus_tag="L1U99_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBN1213621.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            6422..7318
                     /gene="murQ"
                     /locus_tag="L1U99_003170"
     CDS             6422..7318
                     /gene="murQ"
                     /locus_tag="L1U99_003170"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBN1213622.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            7332..9314
                     /locus_tag="L1U99_003171"
     CDS             7332..9314
                     /locus_tag="L1U99_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1213623.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(9379..9825)
                     /gene="nrdI"
                     /locus_tag="L1U99_003172"
     CDS             complement(9379..9825)
                     /gene="nrdI"
                     /locus_tag="L1U99_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBN1213624.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            10036..11460
                     /locus_tag="L1U99_003173"
     CDS             10036..11460
                     /locus_tag="L1U99_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1213625.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(11641..>12083)
                     /locus_tag="L1U99_003174"
     CDS             complement(11641..>12083)
                     /locus_tag="L1U99_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1213626.1"
                     /translation="AIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLW
                     LILSLVLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQ
                     NQIGNEEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
BASE COUNT         3861 a         2135 c         2639 g         3448 t
ORIGIN      
        1 aacgagcaga aagctataag caggaattta taaaaagaga tgttacgacc aactatttca
       61 ttcttccaca tcgagggaat gaacaacctg gatatcttac ttatgaagag tacctgaaaa
      121 aaacagggga atcgcgcggg attctggaac tgttgcggga gggtcagcaa ggagtgactt
      181 tgcggacatt tgaatccatg tattttcaaa agaaactagt gacggataat caagcgattg
      241 ctcattatca tttttatcgt cctgaaaata tttttttgct tcgagaacgt gatttagatg
      301 aattaccgga atttctgcat acaccattta agccaatcct atcagagcta ttggaatttt
      361 atgatgcaga aaattgggca aaacgattta tcactaacga ttccactatt tatgagcaat
      421 acgaatatga cctctcctct gttgaaaaca aataaaaaac ctacattttg aagagattat
      481 gtactgaaac aaacaagcac aattcttatg gcatcatgag agttgtgttt tctttttgat
      541 cttttattgg gcttaaaaaa agagaaccag ctgctgattc agctgattct catcagagag
      601 ccttttattc tgcgccaagg attccttctt ttgcatggac taattgggtc aaaaaggcac
      661 aatatggtgt agcaatatca tatttttgtc cttttcgcca aatggcacca ttgatgtagt
      721 cgatttcagt caaacgatgg tttttgatca ggtcttggta catagatggg taatgcaacc
      781 cgatgttgtc aggatcataa gtagaagcaa tatgttggta cacttcttct tgatctagta
      841 tgattccttc ttttgctgcg atagaagcaa attcagatac gattgttcga accatgctct
      901 ctgccgcttt ttgcgcgcct agttcagcaa tattacaatc caaaatcgtg cataaaccat
      961 tcaatgttcc atttacacaa gcttttcgcc aaatggaata acgaacgtta tggctataga
     1021 tcggatttaa atttgcttct tgaaagactt ctacaacttt ttttgtaaat gcttcgcctt
     1081 ctggttccaa gttctctagt tcgatttctc catcacctaa caatgtgact tttccgggac
     1141 cagctagacc agctgtccac atcgtgatcc caaataagat atttttcttt ggcacatatt
     1201 tttccagtac atcttcatga cctaatccat ttagtaaaca caaaacataa gtattgtcag
     1261 taataatgga ttggatcgaa caaaacatat catctaattg attggctttt gttaatgcta
     1321 cgatcaagtc cacgtgttcg ttgctttcga tgatttcttc tggtgaatag attggcagtt
     1381 ttgcgaccac ttctttaccg ttaaagtcag caatcaaccc atttgtacga atggcttcaa
     1441 tgtgagcagg ccaacgatcg atcaagagga cctcatttcc gctttgatgt agcatcaatc
     1501 cgattcggct gcccattgct ccggccccag ctattgcgat tttcatgttt tttctctcct
     1561 ttattcaatg agttcccttt tagtatatag aaaaatggaa gaaaatagca ttgttttgtt
     1621 tgaaaaaaat gaaaaaaagt gtcttactta agaagaaagt gagggataca gatggatatt
     1681 ttggcggcaa ttgattcatt taaaggaagt gcttcttcat ttgaactaaa tcaggcagtt
     1741 ctaaatggct gggaagatcg taaaggaaga aaaatcaatg tgccgattgc agatggcgga
     1801 gaaaatactg cagaagcaat ctattacgcg ctcaggggaa catggcgtac cattgatggg
     1861 atggatctct tattccgtca gcgaaaaatc agctatttat tgacaacttg gcaaggaaaa
     1921 aacaccgcag tcatcgaatc tgcacaagca ttggggttag atctacttga taaaccaacg
     1981 gatcaaacta tccgacttgc ttccagttat gccttaggag aacttattaa agatgcactg
     2041 cttcaagaag tagaacaaat tattgtcact ttaggaggaa gcgggtgtag cgatggtggt
     2101 ctaggattac tccaatcctt gggtgcttct ttagaagggt acacagaagg aaatccttta
     2161 ttatctacta aaaaacttca ttttgatcga agaaacgttc ttgtttctaa agtaaaattg
     2221 attatcgctg cagatgttac caatccatat acaggtcaac aaggagctgc ttggcaattt
     2281 ggaagacaaa aaggaggaat agatacgacg ctagctttct tagataaaca agcaggaaag
     2341 attgctcagc aaataaaaga tttctgggag gtggatttag atgatattcc aggaagtgga
     2401 gcagcaggcg gtattggtgg agcccttttt ttgttgggag cgaagatggt ttctggtttc
     2461 gatttagtca gccaaatcac tggattggaa aaaaagatcg aacaagcaga tgtcatcatt
     2521 acaggagaag ggcggatcga tcagcaaacg atccacggaa aagttccata cggtgtagca
     2581 gtgcttgcaa aaaaatatcg aaaaccaata atcgctattt gcggaagtag agaccaagag
     2641 ctagaaggac tttctgattt tctcccaatt gtcttaagta ttcatttggg tccaataggt
     2701 ttagaagaag caatggaaca caggcaaaca ttagaaaaaa caaaaatctt aggacagaca
     2761 cttagcagat ttttcaccat cctcccgaag tagttgacaa aatcattttc tttatgctat
     2821 cgtaatttca aatataggac aaagtgaggg atccgtgcat tgaaaaatta agtcgattga
     2881 tgaaagctgc attcagactg taccttgtgg agacaaggaa gcagtgtgca gattttcggg
     2941 attggcttgg ttttttcgat gtatgggtct ttttgtgtgt atccaaccct tgcatcctct
     3001 ttagccagtt ctgaaaatag gactggtctt tttttacgag gtgatggaaa atgtctaaaa
     3061 tcgaaataaa aaatctgaca ttcggctacg acagccaagg cacattatta tttgaacaag
     3121 caaatctaaa ttttgacaca caatggaaac taggacttat cggacgaaac ggtcgaggaa
     3181 agacaacttt actgaatatt ctacaaaaca aactacctta tcaagggcaa gtaatccatc
     3241 agcaagaatt tgcctatttc ccgcaacaga caaaagataa agaacgttta acctattacg
     3301 tgttaaatga tattacggat tttgagatat gggaaatcga aagagagctc caattgatgc
     3361 aaacagatcc tgaaatctta tggagagaat tcagcacact atcgggggga gagaagacaa
     3421 aagtcctact ggcactttta tttgtggatg acactcattt cccgttaatc gatgaaccaa
     3481 cgaatcattt ggatatctct ggtagaaaac aagtagcggc ttatttgaaa aagaaaaaac
     3541 aaggcttcat cgtggtcagc catgaccggg gatttatcga tgaagtagtg gaccatgttt
     3601 tagcaatcga aaaaagtcaa ctggaacttt atcaagggaa tttctctatc tatgaagaac
     3661 agaaaaaact tcgtgatgaa tttgaaatgg ctcaaaatga aaaattgaaa aaagaagtca
     3721 gtaggctaaa gaaaacagca gctgaaaaag ccgaatggtc tcgttcccga gaaggagata
     3781 aaacaaagaa acaagtcgga ttcatcgata ctgaatctag acgagtgaat aaaggagcag
     3841 tgggtgctga tgctgcacgg acgatgaaac gatccaaagc aatcgtgaat cggatggaga
     3901 cccagatcag cgagaaagaa aaactattaa aagatatcga atatatcgat tctttgacga
     3961 tgaatagcca agcgtctcac cataagcgac ttttaagcgt agaagatctt caattagggt
     4021 atgaaaatct gttattcgag ccaattcatt ttacaatcga gcctcatcag cgggtggcga
     4081 tttcaggtcc taacggtgca ggaaagtcat ccattatcca ttatcttctg ggggcattca
     4141 acggcaaggt tataggagaa aaataccagc caaaacatct gagcattagt tatgcaagcc
     4201 aaaattatga agacaatcga ggaacgttgg cggaatttgc agagaaaaac caagtagact
     4261 accaagcatt tttgaacaac ctccgaaagc ttgggatgga aagagatgtt tttcataaca
     4321 agatcgagca gatgagtatg ggccaacgga aaaaagtgga attggctaaa tctttatcac
     4381 agccagctga actatataca tgggatgaac cattgaatta tttggatgtc ttcaatcaag
     4441 aacaattaga acaactgatc ttgaacgtga aacctgccat gttactagtg gaacatgatc
     4501 aaaccttcct ggataaagta tctactgaga ttatttctct tgagagaatc taacccttgt
     4561 aatctcaaga acaacaaggt atggttaagg ggaactttgc caacgaagga gagaatcaca
     4621 tgctttatgt aacgagacac ggagaaacaa cttggaacgc acaaggatta gtttgcggac
     4681 gggcagatgt gccgctgact gaaaaaggac agatgcaggc acagaaacta gcagaaaagg
     4741 tagtagattt gcctgttcca atcacgaaaa tcatccattc ccctcttcaa cgagcaagag
     4801 atacagcaca agcagttgct gatcgtctca gcttgccgct gaccgttgat gaacgattgg
     4861 tagaaatgga ttttggggat tatgatggac tgccaagcaa agatgagaac tttcaaaaag
     4921 cacgtttagc gttcgctgta cgattcccaa atggggagtc agtcttagat gtgtatgcac
     4981 ggatcgttcc tttattgaaa gaatgcatcg aagacgaaga aaatgtctat ctgttagttt
     5041 gccataatgc cttgataaga gtgatcaatg cttattttca tccgatgcct aatgaggggt
     5101 tctttacatt catggtagat aatacagaat tggtttctta tgagtaatta tgtttttgtg
     5161 ttatttaaat aaaatatttc aaggcactgc ttttgcttag cagtgccttt tttaggttat
     5221 gacaattctt ttgataatat aaactcaacc tttagaaatg aaatttaatt attttaataa
     5281 aagtattgaa attttgtttc tttagatata tactctagtc atagaaatga agacggatac
     5341 agaaaaagag ggataatatg tttggctttt caatatttat gaacgattct ttgtcagaag
     5401 agaagaaaca gtatatccgc caaatggcat ccaatggctt tgtcggtatt ttcacttcca
     5461 tgcatatacc agaagatgat gtttcggcat atcaaaagcg attgatcgaa ctaggaagcg
     5521 aagcgaaaaa gaataaacta gaattgatgg tcgatatttc aggagaggca ttggaacgag
     5581 cgggtttttc attagaagat ctaacgcctt tgaaagcaat tggtgtaaca ggtttaagaa
     5641 tggattatca tatttccaat cagcagattg ccgactggtc acatcaattg aaaatcagtt
     5701 tgaatgctag cacgatcacg cctaaagata tcgatgaatt gaaagaagca gaagctgatt
     5761 tctcacagat tgaagcttgg cataattatt atccacgtcc cgaaacaggg ctggacaaag
     5821 aatggtatca gaaaaaaaat caatggctca aaattcaagg tctccttgtc caaggttttg
     5881 taccaggaga tacagagttg agaggcccac tatatcaagg attgccaact ttggaagaac
     5941 atcgagggat ccatcctctt gcaggcgctc tagatctatt agcaagtaac acggatattg
     6001 tttacatcgg agatgcaggt ctgtcagaaa acgttcagga gcaatttgct tctttccaaa
     6061 aagaacagac agtcttgctc catacggaac ctgtagatga agaattttac gaatatatat
     6121 tagggaagca tacgaatcgg caagacgatg caagagatgt catacgaagc gtagatgcac
     6181 gttttcgaga gattccgcct atcccagcaa gaaatacagc tacgcgtatg aaagggtcta
     6241 ttactttaga taacgaaaag tatttgcgct atatgggtga gatccaatta accaaatatg
     6301 atttgccagc ggatgaaaaa gtgaatgtag tagctaaagt tatcaaagaa gagctaccat
     6361 tgatcaacca aatcaaagct ggtatgaact atcaatttat aagaaaagaa ggaagataaa
     6421 aatgagcaaa atcaatttag agaacctaac aacggaacgc agaaaccaag aaacttttgg
     6481 attagatgag atgagtattt ctcaagccgt tcaactaatg aacaaagaag atcagaaagt
     6541 ggccgctgcg gttgaaaaag aactgacaag tatcgaacca gtgattgcta acacgattga
     6601 gtcctttaaa aaaggtggac gtctgattta tatgggagcc ggaacaagtg gaagactagg
     6661 tgtgttagat gctgctgaat gcgtaccgac attcggtgta gaaccggaaa tggtcatagg
     6721 tctaattgct ggtggagaag aagcaatgac tgtagctgtc gaaggggccg aagattctta
     6781 tgagctaggg caagaagatc taatcaagct gaatttgaca aaaaatgata tagttattgg
     6841 tatcgcagct agcggtcgta caccatatgt gatcggtgga ttagattacg caaaatcgat
     6901 cggtgctgtc acaggaacga tttcttgcaa taaacaagcc gaaatcagta aacacgcgga
     6961 tttcccaatc gaagtcgatg caggtccaga atttttgaca ggctctactc gattgaagtc
     7021 aggaacagca caaaaactta tcttgaatat gatttctact atcagtatga ttggtatagg
     7081 taaagtattc aataacttga tggtcgatgt caaaccaaca aatgaaaaac taatcgaacg
     7141 ctcaaaacga atcatcatgc aagcgacaga agctgattac gaaacagctg aaaagtactt
     7201 tgaagaagca gatcaaaatg ttaagctggc tatcgtcatg attttgacaa atagtgataa
     7261 agaggaagct caagcaaaat tagctgaagc aaacggattt gtaaaaggga ccttatgagg
     7321 gggaaaagac catggcaaaa aacgaactga ctttggaaga actggcaaaa caaatttata
     7381 aaggggcagg cggcatgggc aatgtagaaa gcattgtcca ctgcatgact cgtgtgcgta
     7441 tgaagatcat caatgatgat cttgtaaatg tctctgaatt aaaagcgatt ccaggagtgc
     7501 ttggtgtagt agaagatgaa cagcttcaag tcatcatcgg acctgggaaa gtgaacaaag
     7561 tagcacagca aatggttgat ttggcaggcg tgaaattagg agaaaaactt tcttctgtaa
     7621 gtacagctac agcaaattca tcagcatctg gaaaagaccg tgtaaacgaa cgggcacaag
     7681 aaatgaaagc ggcacaaaaa tcgaaacaaa aaccatctaa aatcaaatcg gtattaaaag
     7741 acatttctaa tatctttgtg ccaatgattc ctgcatttgt cggtactggg atcgtggcag
     7801 ggattgccgc agttttagca aacttagtca cagccggaac acttgatgca gcaacatggc
     7861 aacaatatat cgatgtgatg aacatcttga aaaacgggat gtttagctac ctagttatct
     7921 atacaggtat caatgctgca caagtttttg gtgcaacacc aactcttggt ggagttatcg
     7981 gggccgttgt gatgctgaca gggatgaatc cggaagcacc actgaaaaac ttatttactg
     8041 gtgaagctct tgcagctgga caaggtggga tcctaggtgt catcttcgct gtttggctat
     8101 tgtcaatcgt tgagaaaaaa ctgcataaag tagtacctga tgcggtagat atcatcgtta
     8161 caccaactct ttcattgatt gccatcggtc tgattgaaat tttcttcatc atgcctttag
     8221 caggtttcat ttctgatggc atggtcggtg ggatcaactg ggtacttggc gttggtggag
     8281 catttgccgg cttcgttcta ggcacattat tcttgccgat ggttatgttc ggactgcatc
     8341 aaattttgac tccaatccat gtgcaaatga ttgatgaaac tggtcgtacg ctattgcttc
     8401 caattcttgc gatggctggt gcaggacaag tgggtgcagc attggcatta tggattcgct
     8461 gcaaaaaaga taaagaatta acagaaatga tcaaaggagc tttaccagtc gggatcctag
     8521 gaatcggcga accattgatt tacggagtaa cattacctct aggacgccca tttattactg
     8581 cttgtatcgg tggaggtatc ggcggggcag tgatcggaat gatcggaaat gtcggggcta
     8641 tcgctattgg accttcagga gccgctttga tcccattgat ctctgacggt aaatggttag
     8701 gctacatcct tggattattg gcagcttatg ctggtggctt cgttgctaca ttcttcttcg
     8761 gtattcctaa agaccgttta gaaaaagaag aattagcgac tgaaacagcc acagtaaatg
     8821 aagtgcctga aaaagtagta cctcaaactt cagctgaaag tgtgactatc ctctcatcag
     8881 ttgctgacgg aacagttgtt tctttagata aagcaagtga tccagttttt gcacaaaaga
     8941 tgatgggtga aggctacttt gtagaaccag aaaacggaca tatctattct ccagttactg
     9001 gggtagtcag ctctgtcttc ccaacgaaac acgctattgg gatcacaacg ccaaatggtt
     9061 tagaaatctt gcttcatatg ggaatcaaca cagttgactt aggcggtacg ccatttgatg
     9121 tgaaagtaac agaagggcag caagtgacac ctgatacgct tgtagcagaa gctgacttag
     9181 aagcgatcaa agcagcaggc aaagaaacat ccatgatcgt cttggtaacc aatatggatc
     9241 gtgtaaaaaa ctttgtcttg gaaaaaacag gtaaagcaaa agcaaaagca cctgtgatgg
     9301 atgtcaaagc ttaatatgat agaaacaata gaaacgaaag aagaaactga aatctatttt
     9361 tcagcttctt cttttttatt atttattgtt ttctgctaaa atctgataaa ttcgtgtcac
     9421 atcagatggt gttccccgta attcataatc tgccaagaaa ggaaagccaa atgtttgtgc
     9481 atattgtttg gctgttagac aatactgatt attgaagttt ttatttccgc taccgactac
     9541 accaagacaa agtttatgat tgtcttcatg ttccagatat tcacgcatcg tttcggtcaa
     9601 gatttctgta tcaccgttat ctaaaccatt tccgccgtct aaataagtag gaacgaaagt
     9661 aaaaaatggt tctgtttctt tcgtaaaatc actattttca tggatttctt ttaaagtaac
     9721 ttcaggattg acaggatctt ctgcatgcat tttttcagca tattctgcta gatgtttggc
     9781 aaaggcacgc gtatttcctg aaatcgatat atataaaatg ttcatggatc atcctccaat
     9841 tctttccttt tagtatagca tcttttttaa gttttttggt ggtgtaattt ggaaagggac
     9901 taggcgcttt gcttgtataa tgagaaaaaa gccggtagaa ttatatttct attaaagttt
     9961 ttattaatta agtaaaaata aaaaaggttt gttatacttt ttgataaaag cggttttatt
    10021 ttggaggatg cttacatgga tacagagcaa cagaaaaaag gaattggttt aattccactt
    10081 gctgccttag taattggttc agcgattgga ggtggcgtat ttggtattat gacggacatc
    10141 tccggatcgg ctggcggccc agctattttc agttgggtac tcgtaggaac agcaatgttg
    10201 atgctctcct tgtcgatcaa taatatcaat aaaaaacgtc cagatttaaa aggcgggatc
    10261 tttagttacg cagaagaagg ttttggccgt ttcgctggtt ttatcagcgg ttggggttac
    10321 tggctcacat gctggttagg caacgtagct tttgcaacat tgttgatgag cgcattagga
    10381 tatttcttcc cagtatttga aggtgggcaa aatctggcat cgatcgtgat gagtacagtc
    10441 tttttatggg gatatgcatg gctagtgaat cggggagtcg aaaatgctag tttcgtcaat
    10501 gctatcgtca cattctgtaa attagtgcca ttatttttat ttattgtagt agctatcagc
    10561 acgttttcga tccaacaatt cattgataac ttttctagcg acattatatt gaatgcgaat
    10621 ggacagccga tcccgttttc cagtcaagta ttgagttgca tcatggtgat gctttgggta
    10681 tttgttggta ttgaaggagc ctctgtcgta ggttcacgag caaaaaaaca atcagatgtt
    10741 gggaaagcaa cgattctagg gatattcggc ttgattatta tttacgtctt ggtttccatg
    10801 cttccatatg ggacaatgac gatgaatcag ctgcaaacga tcaaggcgca gcctgctatg
    10861 ggctatgtgt ttgaaatgat ggttggtaaa tggggagcag tcgtgatcaa cggcggtttg
    10921 atcatttctt tagttggtgt ttggctctca tggacgatct taccgattga aacaatggga
    10981 aacatggctg aagacggact tttgcctaaa gcatggggaa aactcaacaa aaatggggca
    11041 ccaacttatg ctatcgtatt gacgacgtta tgtacgaatg tctttttact ttcattatta
    11101 ttcactgaca gtgcttataa ctttgcttac acacttggta cagcagctat tttcttcacg
    11161 tggcttttct taggattgta ccaaatgaaa ctttcttatc agcggaaaga atgggtccaa
    11221 tttttagtag ggcttttagc aagtgccttt caagtatggg ctatgctagt cgtagccttt
    11281 aatgaagtaa tgcttgttct tgttcttttc ttgccaggca tttattttta cctcaaagca
    11341 cgtaaggagc aaaacgagcc tgtacaacat atccacttag ataagatttt acttataggt
    11401 gtgacgatgg tcggagtgat tgcaatggtt ttatttgcca ctgggatgct tcacgtatag
    11461 aagtataaaa gaagtataaa gagaggttgt gagcctgtcg tttattcaaa aacatactag
    11521 gaaaggagct gtgacacaaa tgttgtcaca gctccttttt cagaataaac ggtgtttaag
    11581 agacagccaa tcggcaataa ggctgaacgt ctctttcaca gcctcttttt tgatgagtca
    11641 tcatacattt tttcgcttaa atacgagata tcctaatgct aagaacaaaa cgatgtaagc
    11701 taaattaccg aatagcattt gattagtaga aagatgagtc aattgcttca tgatctcttc
    11761 gtttccaatt tggttttgca gattcaacat actgatcgga ttccatttga tccactccca
    11821 tttttggatg agtgcaataa ggataccaga tatgattgac gaagcaaaat aaaagacgat
    11881 tcctgctgag atggatgcgc cggaactatt gataaagcaa gcaatcatca acactaaact
    11941 taaaatcagc cataaaccga tataactacc caaagtataa gtgaacaagc tttggatcag
    12001 tgtttgacca gtagaaacct tctccgtgaa ggaaatcgaa gggaaaagaa tcagtttcat
    12061 caacacagtg acaataatag cta
//
LOCUS       DAFLVO010000271         5954 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.guided.119, whole genome shotgun sequence.
ACCESSION   DAFLVO010000271 DAFLVO010000000
VERSION     DAFLVO010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5954
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.guided.119"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..1167)
                     /locus_tag="L1U99_003175"
     CDS             complement(<1..1167)
                     /locus_tag="L1U99_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBN1213627.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSN"
     gene            1446..2252
                     /locus_tag="L1U99_003176"
     CDS             1446..2252
                     /locus_tag="L1U99_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HBN1213628.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            2270..2977
                     /locus_tag="L1U99_003177"
     CDS             2270..2977
                     /locus_tag="L1U99_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBN1213629.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGETFSFWLFLHTP
                     LTIIQRRGHEVKEFPEPNSDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKII
                     GQVFADKEPQALYKITNGSIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKC
                     KICYPLPESVDIQEENQ"
     gene            2974..3945
                     /locus_tag="L1U99_003178"
     CDS             2974..3945
                     /locus_tag="L1U99_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HBN1213630.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVSHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            3938..4966
                     /gene="vanB"
                     /locus_tag="L1U99_003179"
     CDS             3938..4966
                     /gene="vanB"
                     /locus_tag="L1U99_003179"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HBN1213631.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKAAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            4972..5580
                     /locus_tag="L1U99_003180"
     CDS             4972..5580
                     /locus_tag="L1U99_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HBN1213632.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(5646..5819)
                     /locus_tag="L1U99_003181"
     CDS             complement(5646..5819)
                     /locus_tag="L1U99_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213633.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
BASE COUNT         1690 a         1223 c         1499 g         1542 t
ORIGIN      
        1 atttgaataa ggcaattcga gggctaaacg aatgccggat tcatagttta taaaagcttt
       61 ttttatagaa tgcagttctt ttggaacgga attgggcatc gttcttacaa gtttaaagaa
      121 agtgtccgcc tctttgtcgt gaaacgcttg aagaatttct tgatagtaaa aataggcgat
      181 tcgtaattcg tcagagatcg aaagcagacg atccaccact tcactttcgg tgagatacgc
      241 ccaaccaaaa ttgcgccatt tggtccattt gtcataaaca agcttgtcct gtcgtttgat
      301 cagaagccga gacaacgcct ttaattgtcg ataatatttg gcttgtgttg gatcgtttcg
      361 atcaaagctt ttcatgattc gtacgcgaat atcctcaaat ttacgaatga gatgtttgac
      421 aatgtgaaaa cgatccacaa cgagttttgc ctttggaaaa cattccttta tcagagaggc
      481 ataagaaaca ttcatgtccg tcacgatgac ctttaccttc aatcgtgcgc gtcgttcaaa
      541 ttgcataaaa taagaaacga gagccttttt cttccgtgaa ggaagaatat ccagtaattt
      601 tccagtatcg ccatccatac aagaaaagga gtagggaccg acttgatttt tcagtgaacg
      661 aaattcatcc attaataaac aacgcggtaa ccaatttctt tttacttttg tcatggggat
      721 cagagaagcg agtgtccgag aaacggtcga ccaagaaacg ccgcaatgct tagcaattgt
      781 cgtcattgct tgtttttcag ttagctcttc taaaatttta tagcgcactt gtttagcgat
      841 aaagcagttt ctatcgacaa tgtaggtatt cgccgtaaaa taggtgtggc agccacgaca
      901 gtggtagcgt tgtttcgcta aagcaagata agtcagttgg ttcgcacatt tattaagttg
      961 aatgagcgat tttttctttc cgttcttaac gatcatgcct tcatgattca tctgtttaca
     1021 caaaggacag cgacgaattt ctttacttaa cgtcgcagaa acaacaagac tcttgatatt
     1081 cttaatgctc ttcgattcca catttgtgat gaaaatgttt ttatctttga ttccaagtag
     1141 tagtttgata tgatgaagat caggcataca gaacgctcct ttgattgtgt tgtggtgatt
     1201 caattctaac ggagcttctg tatgttttgt tttttcatgc tcaaaaggga ccgatagaat
     1261 gattttctat cagtcctaga aattatagag ccgattttga ccgacaggta taaccctgcc
     1321 ggtctttttt tgctgctaca ggaaaactac agactggcta cagggaaagt acagatgcgc
     1381 ttgccataat aacaatcgta ccagccacaa atcgtagttt tattgcaaag gaggcattcg
     1441 atcaaatgga aaaaagcaac tatcattcca atgcggatca tcacaaacgg catatgaaac
     1501 aatccgtgga aaagcgggct tttctatgtg cgttcattat ttcgttcaca gtctgcacgc
     1561 tgtttttggg gtggagactg gcttccgtat tggaggcaac acagataccg cccatccctg
     1621 caactcatac aggcagcagc actgacgtag tggagaattt ggaggaaaac gctcttgcca
     1681 ccgccaaaga acagggagat gaacaggaat ggagcctgat tttagtgaac aggcagaacc
     1741 ccatccccgc acagtacgat gtggagcttg agcaactatc aaatggtgag cggatagata
     1801 ttcggatttc tccctatctt caagatttgt ttgatgccgc aagaactgat ggagtttacc
     1861 cgattgtcgc atccggatac cgaacaacag aaaaacagca agaaattatg gatgaaaaaa
     1921 ttgccgaata taaggcgaaa ggctacacct ctgcacaggc taaagcggaa gcagaaactt
     1981 gggtggccgt gccgggaacg agcgagcatc agcttggtct tgctgtggat atcaatgcgg
     2041 acggaattca ttcaacaggc aacgaggttt atagatggct ggatgaaaac agctatcgtt
     2101 ttggttttat tcgtcgctac ccaccagaca agacagagat aaccggtgtg agcaacgagc
     2161 cgtggcatta ccgatatgtt ggcatcgaag ctgccacaga gatgtacaac caaggggttt
     2221 gccttgagga atatttaaaa ccagaaaaat gagaaaagga tgttatgtta tggacagaaa
     2281 aagattgaca cagcgtttcc cgttcctgct tccaatgaga cgggcgcaga gaaaaatgtg
     2341 cttttatgcg ggaatgagat ttgacggctg tcgctatgcg cagacgatag gggaaaaatc
     2401 gctttcccat ttgctctttg aaacggattg cgcattatac aaccacaata ccggatttga
     2461 catgatatac caggaaaaca aggtgttcaa cttaaagctg gcagcaaaga ccttaaacgg
     2521 cttattgata agaccggggg aaaccttttc tttctggttg ttcctgcata cgccattgac
     2581 aattatccag cgcagaggtc acgaagtaaa ggagtttcca gagccaaaca gtgacgagat
     2641 taaaggggtg gatgcaacca tttcagaggg ctggattgat ttaaaagtgc gaaacgatac
     2701 cgactgcacc taccaaatat gggtgacctt agatgatgag aaaatcatcg gtcaggtgtt
     2761 cgccgacaaa gagccccaag cattatacaa aattacaaat ggcagtatcc agtatgtccg
     2821 tgaaagtggc gggatttatg aatatgccca ggttaaacgg atgcaagttg ccttaggtac
     2881 cggggaaata atagattgca agctgcttta tacaaacaaa tgcaaaatct gttatcccct
     2941 cccggaaagt gtggatattc aggaggagaa ccaatgagaa aaagtgtggg cattactgtt
     3001 tttggatgcg aacaggatga ggcaaatgct ttccgcgctt tatcgccgga ttttcatatt
     3061 atccctacgc tgattagcga tgcgatatcg gcagacaacg caaaattggc cgctggcaat
     3121 caatgcgtta gcgtaagcca taagtccgag gtttccgagg cgacaattct tgcgctgaga
     3181 aaggtcgggg taaaatacat ttctacccgc agcatcggct gcgatcacat tgatacgact
     3241 gccgccgaga gaatgggaat ctcggttggc acggttgcgt attcgccgga cagcgttgcg
     3301 gattatgctt tgatgctgat gctgatggcc atacggggtg caaaacccac catgcacgcc
     3361 gtggcgcaac aagatttcag attggatcgt atccggggga aagaactggg ggatatgact
     3421 gtgggagtta ttggaaccgg ccatatcggg caagcggtcg tcaaaaggct gcggggattt
     3481 ggatgccatg tgctggccta tgataacagc cgaaaaatgg atgcagatta tgtccagctt
     3541 gatgagcttc taaaaaacag cgatattgtt acgctccatg tgccgctttg tgcggatacc
     3601 cgccatctga tcggtcagaa gcaaattgga gagatgaagc aaggcgcatt tttaatcaac
     3661 accgggcgcg gagcgcttgt cgataccggg gcgctggtgg aggcgttgga aagcggaaag
     3721 ctgggtggtg cggcactgga tgtgttggag ggcgaggatc agtttgttta taccgattgc
     3781 tcgcagaaag tgcttgacca tccctttttg tcgcagcttt taaggatgcc gaatgtgatc
     3841 atcacacccc atacggcgta ctacactgag cgtgtgctgc aggatactac agaaaaaaca
     3901 atcaggaatt gtctcaattt tgaaaggagt ttacagcatg aatagaataa aagtcgcaat
     3961 catcttcggc ggttgctcgg aggaacatga tgtgtcggta aaagccgcaa tagaaattgc
     4021 tgcgaacatt gatacggaaa aattcgatcc gcactacatc ggaattacaa aaaacggtgt
     4081 atggaagcta tgcaagaagc catgtacgga atgggaagcc gacagtctcc ccgccatact
     4141 ctccccggat aggaaaacgc atgggctgct tgtcatgaaa gaaagcgaat acgaaacacg
     4201 gcgtattgat gtggctttcc cggttttgca tggcaaatgc ggggaggatg gtgcgataca
     4261 ggggctgttt gtattgtctg gtatccccta tgtgggctgt gatattcaaa gctccgcagc
     4321 ttgcatggac aaatcactgg cctacattct tacaaaaaat gcgggcatcg ccgttcccga
     4381 atttcaaatg attgataaag gtgacaagcc ggaggcgggt gcgcttacct accctgtctt
     4441 tgtgaagccg gcacggtcag gttcgtcctt tggcgtaacc aaagtaaacg gtacggaaga
     4501 acttaacgct gcgatagaag cggcaggaca atatgatgga aaaatcttaa ttgagcaagc
     4561 gatttcgggc tgtgaggtcg ggtgtgcggt catggggaac gaggatgatt tgattgtcgg
     4621 cgaagtggat caaatccggc tgagccacgg tatcttccgc atccatcagg aaaacgagcc
     4681 ggaaaaaggc tcagaaaatg cgatgattac agttcccgca gacattccgg tcgaggaacg
     4741 aaatcgggtg caggaaacgg caaagaaagt atatcgggtg cttggatgca gagggcttgc
     4801 ccgtgttgat ctttttttgc aggaggatgg cggcatcgtt ctaaatgagg tcaataccct
     4861 gcccggtttt acatcgtaca gccgctaccc acgtatgatg gccgccgcag gaatcacgct
     4921 tcctgcactg attgacagcc tgattacatt ggcgttaaag aggtgataag tatggaaaat
     4981 ggttttttgt ttttagatga aatgttgcat ggcgtccgtt gggatgccaa gtacgccaca
     5041 tgggataact tcacaggaaa accggtggat gggtatgagg tgaatcgcat catcggcaca
     5101 aaggccgtgg cgtttgctct gcgcgaggca caaatccatg cggctgcgct tggctatggc
     5161 ttgcttttat gggatggata tcggccaaga actgcggtgg actgcttcct gcgttgggca
     5221 gcgcaaccgg aggacaatct cacaaaagaa aaattttacc ccaatataga gcgagccgag
     5281 ttgattacaa agggttatgt ggcctcacaa tccagccata gccgtggaag cgcaattgat
     5341 cttacgctct accacctgga tacaggggaa cttgtttcaa tgggaagtaa cttcgatttt
     5401 atggacgaac ggtcgcatca tacagcaaaa gggatagggg atgcagaggc acaaaatcga
     5461 agatgcttgc gtaaaatcat ggaaagcagc ggatttcagt cttatcgctt tgaatggtgg
     5521 cactataagt tgattgatga gccatacccc gatacctatt ttaattttgc cgtttcataa
     5581 tgaaagtatt ggttttgtat cagattttgg atttgataaa atctatgctg gtcatggaca
     5641 atcttttact ggaaagtggt taaagcatct tttgtaatac attgcaaatt atagtattca
     5701 atctgcccag cggcagaaaa gaaaaaaacc gctgttgggc agacctttcc cacgcccatt
     5761 ttgtattttg ctggcggcgg ttttgagaaa tcaaggccgc cgttcttttc tggcagcaaa
     5821 aggtgtggcg gcccatagga ggatgccgct atgctgtttt gctattgcca tgctctaatc
     5881 cacttccacc actcaaaaaa agccttgccc ctccatgaac tgaaccccaa aagttgaact
     5941 atttaatgga ctgt
//
LOCUS       DAFLVO010000272         5283 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.guided.130, whole genome shotgun sequence.
ACCESSION   DAFLVO010000272 DAFLVO010000000
VERSION     DAFLVO010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5283
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.guided.130"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            124..816
                     /locus_tag="L1U99_003182"
     CDS             124..816
                     /locus_tag="L1U99_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBN1213634.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSWKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
     gene            1143..1640
                     /gene="dfrG"
                     /locus_tag="L1U99_003183"
     CDS             1143..1640
                     /gene="dfrG"
                     /locus_tag="L1U99_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBN1213635.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(1712..3664)
                     /locus_tag="L1U99_003184"
     CDS             complement(1712..3664)
                     /locus_tag="L1U99_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBN1213636.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3671..3907)
                     /locus_tag="L1U99_003185"
     CDS             complement(3671..3907)
                     /locus_tag="L1U99_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213637.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            4309..4599
                     /locus_tag="L1U99_003186"
     CDS             4309..4599
                     /locus_tag="L1U99_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213638.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT         1782 a          869 c          916 g         1716 t
ORIGIN      
        1 gattaaatga gtatttgata gtatttatat taaaattaca tatgtaattt aaaaacgctt
       61 gacattgtgt ttgagatcac ttacttttag catgtaaaag tattggatta aggagctatg
      121 caaatgaaaa agaaatttat tactggtggg attgtcgttg catttctatg tctaattggc
      181 tacacaggca cgcggtacgc aaatgaaatt attttgtggg gtggagagac agatattgat
      241 acaatcaatg agaatctgac acagcttgat catacattga cagataaaga gcaagcgatt
      301 acagatctta ccgctcgact agcacaaaaa gaacagacat tgcaagattc aaaggcagat
      361 gtccaagaat accaaacaaa agtaaatgaa ttagaaaacc aaaaaaatca atcggcagca
      421 gaaaaacaaa acttagaaag tcaattagtc agcaaggatg cacaactaca aagcaaacaa
      481 aatgaaatca atgtcaaact agatgagatc aaccaaaaaa atgatgaaat caatcatctg
      541 aatgcagatt ggacagcaag actacaagaa gcacaagcaa aactttcaga attacaaaat
      601 actgtaaatg gtttgaatca acaaatcgca acactgacac aagaaaaaac aaatgtagaa
      661 actcagttaa cagatacaca aaagaaatta gacgaagcaa ctgctgaaaa ctcaagctgg
      721 aaacaatata ttcaaaagtt agaaaaagca aaagatgaag tggaagatac agctgataaa
      781 tctcagcaaa ttgttgaaga acatttgcgt aaataatctt tcttaacaag taaacctaaa
      841 ttagtaaaga agcaacagta atctatacta agtagttcag ttttggagta caaaatgaca
      901 aaatgtactt caaaatggac tacttttttc attttaactt acataccaaa ttacatacaa
      961 aatgatttat aaaatgcaat tgaaaatgat aattgaatga aaatttgtga ttttgtggta
     1021 ttatgataat ataacttata gaaaaaattg cttattcaac taacgggcag gataatgaga
     1081 aaaggttttt tgatagaaat aagaaattag atggtaaatt agttaaaaag gctgtgttat
     1141 aaatgaaagt ttctttgatt gctgcgatgg ataagaatag agtgattggc aaagagaatg
     1201 acattccttg gaggattccc aaggactggg aatatgttaa aaatactaca aagggacatc
     1261 cgataatatt aggtaggaag aaccttgaat caatcggaag agccttacct gacagaagaa
     1321 atattattct gacgagagat aaggggttta cctttaatgg ttgtgaaatt gttcattcaa
     1381 tagaagatgt ttttgagtta tgtaaaaacg aagaagaaat ttttattttc ggaggagaac
     1441 agatttataa tttgtttttc ccttatgttg agaaaatgta catcacaaaa atacatcatg
     1501 aattcgaagg agatactttt tttccagaag tgaattatga ggaatggaat gaggtatttg
     1561 cccaaaaagg gataaagaat gataaaaatc cgtataacta ctattttcat gtatatgaaa
     1621 gaaaaaactt attgagttaa cgggtgcgtt aattgaagaa gaacagtaaa gataaagcac
     1681 aagagcttgg gattactcca agctcttttt gtcatttgaa ataaattata tctttccaat
     1741 caaattgttt atctgtaatc cctaatcttt gagcaggtgt caaaaccttt ttatccgctg
     1801 atttaaaagg gcgacaaaag ttgtagtaag ttcttagaat tgtaatcgca aattgagcat
     1861 acttcggatt gaagttagcg taaatatagc tcttcttatc accacgagct gttgttaatg
     1921 gtctttcaag agatgatata taacgtctta tctgttgaat aaagctattg gtcgaatggt
     1981 cattaacatt taatagcatc tttgcgattt cgtttggttc cagagcagat aaatccgttc
     2041 tacaatcaac tgaataaaat cctttatcct tagtggctaa tggatgtttg atagggttat
     2101 cggcatattt gcgatatctt tctccatctt tactaatagc ctcttcgtgg aattgatgac
     2161 ttgttagtaa ttcagttaga taatgagatg ccaaagtccg tagaaacttt gttttgaatc
     2221 ctctgatatc tccccaatcg agcagttctg cttttgcttg tccgaattct tttaagcatt
     2281 gttttctgct tttcgtcttg ttaacttggc aaataaaatg atgtgcatcg ctcaacctta
     2341 attctttcgt gaatactcta taaaaggcgt ttctaataga gaagtcatca tcactaatca
     2401 ttcgccattc gtcggcatta accatttgtt taattaacca atagtgagca gttgtagtat
     2461 aaggagcatc aacatttaaa ccatcgacaa atctactcct attagtaatt ttccctaatt
     2521 cgtgaagata agcattccta ttttcgctat cgttagcgga tggttcttgt ggataataag
     2581 accaatctaa cctatcattt ttacgactaa aagtattgag atggtcttct ttgaattttc
     2641 ttgtatcttc atttaattca tccattgaaa tattccaatc ataggcaaca tcagaacgga
     2701 acacatatct tgataagacc tcagcagata caactatata cgtttgcata ttaaggtctt
     2761 caaaccccgt atatttcttt gaaccttgtc ctttcttacg gacgttattt aggtagtagt
     2821 gcatcttgtc cgtattaagc cacatctcgt taaatttctt tgtttgaagg ggttgtgtct
     2881 catatcgttc taaaaactcc aaacaacgcc tatacagcca ctccagctta tgatagtagg
     2941 ttccaactcc aattcctaaa atatcacaag tacgactgac tgaaaccctt ccaacaacca
     3001 tcttagcgaa cattggaaga atggtgttct tttgttggtg ataagtagtg gtttcttctc
     3061 tttttggtag aacattagtg aacttcttac acgccttaca ttgatagcgt tgagatttgc
     3121 ccctactttt cccccttttg taaaattgct tcggctcatt gaatggggtt gattcttctt
     3181 ccgagcagcc ttctttatga aattgataat ctggctcaac atcttggatg ctattgattt
     3241 ctataaggcg tttaatttct tcaacaacag accaattaga taaaggggtt actgtacagt
     3301 tttgcgatac acctctgcca ataggattgt cattgcagta cataccttta tgacctttat
     3361 ctttggaact accagtcatt ttatatcgac ttggtttccc ttttacatct ttgaatttgt
     3421 gctgttcttt cccaaaatta caacaaaacg gattgatgca gtaattatat tgaatgggat
     3481 attcagaacc gttccattta aaagacgttg gcaagaacaa cattttgtta taccttgttg
     3541 caaatcgttt tggagttaat aaatcatatt gtttagccct atcttttaat tcttcgtttg
     3601 aaatcggaat tttaacatct acaatttcat cttccttcgt ggctaatctt ttaagcttgg
     3661 tcattgtcta tcaacccact ctatctttga tacccatttt ttcaacaatc cgcttattac
     3721 ttcgcttgtt ggcaatccat tcaataaact tcttatcgtc taaaatgttc aataagaatt
     3781 catccactgc ttcgctttca gtacgctctg catattcagc gtattgctta actatcaccc
     3841 ttacttgctc tgatatttcc caatccacag acttagcgtt cttatttttt ggctcaagaa
     3901 attgcatagg aaaatgcacc cctttttgct tagtaaattg taaccatttt aacacaccaa
     3961 tttgcattcc tacaataatt atttcacgtt cgcattttta tatacatttt aacttacatt
     4021 ttgtggtgta aattaacaac aaacgttgat ttaacaataa aaaacgagta tcaaattcag
     4081 ttgcaatttg atactcattt aggtttacat tttcactttt tgtactccaa aactgaacta
     4141 cttaaatcta tactgctgcc tctttttttt agtacatgtc cttcatcttc gcaggaagtg
     4201 ccaatatgat tttaagaaag gtaatagaca aaaagtcaaa aagataaaac agagtttctt
     4261 ctttacaaag ggaatgtatg ttcgtataat ggtattgagg tgaaggttat ggagaaaaaa
     4321 tatggaacag tagataagat ccgtactttg caagttagtg ccagaccgtt gatccgtttc
     4381 agtttaaatg gggtcaattg tttgattgct tcccatagtt tgaacttcct agctgaagta
     4441 gacgaaggga tgaagttagt cgttacaggt tattataata atagaaagca atttgttgtg
     4501 agatcctatc atgtgttagg gaaacccaaa attgtggtag aatatgagaa aagtctatac
     4561 ccaagaaaaa aggtccgaca agatgaaaga ataaactaga aaacaagcgg ctgagacaaa
     4621 aatgtcctag ccgcttgttt tggaaagatg gatgcagacg atgggatttg aacccacacg
     4681 agcatacgct cacaagaacc tcaatctata tataactaca tgtatttaag tatttgtgat
     4741 gaatcactaa actttccaaa ctcatttgag ggatattgct taaagattga acagatcaat
     4801 tcgaagccct attagtattc gctcaatggg gggatcagag gccataaaaa gagactagtc
     4861 attactagtc tcaggtagtg gaattgtagg attttaaacg ttcctggaga gtaccggtat
     4921 gtaactcgaa gaggtgatta tcatagtcgt aaaagtaaat tgaagaagcc tcgcctttca
     4981 cacgagaacg tcctggttcg acagttaaac ctaacatttg gatttttgag acaaacgaat
     5041 ctatatcttg ttcgtcaatt ttaaaagcaa tatgattgta tgtctttggc agtttattcg
     5101 acgaattctg cattactgca atccataggt ccttaactaa gaaaaatttt tctggatata
     5161 atgaaaattt ttttgttgac tatcgtagat ttcttttgca tcaaataagg tatttaacaa
     5221 ttaagtattt aaaagataac ttttaagtta tctttaagta atgcttaaag ctatgttata
     5281 ctc
//
LOCUS       DAFLVO010000273         5068 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.guided.131, whole genome shotgun sequence.
ACCESSION   DAFLVO010000273 DAFLVO010000000
VERSION     DAFLVO010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5068
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.guided.131"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..630)
                     /locus_tag="L1U99_003187"
     CDS             complement(<1..630)
                     /locus_tag="L1U99_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBN1213639.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFI"
     gene            complement(591..920)
                     /gene="mobC"
                     /locus_tag="L1U99_003188"
     CDS             complement(591..920)
                     /gene="mobC"
                     /locus_tag="L1U99_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBN1213640.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(1178..1548)
                     /locus_tag="L1U99_003189"
                     /pseudo
     CDS             complement(1178..1548)
                     /locus_tag="L1U99_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            1693..1878
                     /locus_tag="L1U99_003190"
     CDS             1693..1878
                     /locus_tag="L1U99_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBN1213641.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            2036..2203
                     /locus_tag="L1U99_003191"
     CDS             2036..2203
                     /locus_tag="L1U99_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1213642.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            2821..3480
                     /gene="vanR"
                     /locus_tag="L1U99_003192"
     CDS             2821..3480
                     /gene="vanR"
                     /locus_tag="L1U99_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HBN1213643.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            3483..4844
                     /gene="vanS"
                     /locus_tag="L1U99_003193"
     CDS             3483..4844
                     /gene="vanS"
                     /locus_tag="L1U99_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBN1213644.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPNFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLT
                     STL"
     gene            complement(4935..>5068)
                     /locus_tag="L1U99_003194"
     CDS             complement(4935..>5068)
                     /locus_tag="L1U99_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1213645.1"
                     /translation="KIENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT         1352 a         1107 c         1252 g         1357 t
ORIGIN      
        1 aataaacttt cccggcttga tctcatagcc ctgcgcctgc atgagccgca ggaaatcatc
       61 aaaatctttt gcctgcggga tagcggcgtc aatggctgct ttgagcttcg ctttccagct
      121 cgtccctttc cgctgggcgt cccactcggc atagctcttg cccttactct ggccgggctt
      181 caccacggac aatccgtttt ccttgcacag cctgtcgctg gtgcgccgga tataggcata
      241 gctctgtttg ttggaaatgt acttgcgctg atttaccata tccacggcac agaaaataat
      301 gtgattgtgg acgtggccct tatcaatatg ggtagtcagc acatagggat atttcccttg
      361 cagcacttcc tcggcaagct gcttcccgat ctcatgggcc tgttccggcg tggcttcgcc
      421 gggggcaaag gattgtatca ggtggtggcc cagattattg cccttttggt atgcctgcgc
      481 cagcagcatt tcaaattcaa tgtccgctgt ttcataagag caggcaaagg aggccaccag
      541 cagcttgccg tcagttttgt ccgggttctc gatgtagtca agggcttttt tcagcgttga
      601 cttgatagga tgtatctttg taactgccat atctgcgcca gcgccccctt tatatcctcg
      661 atgtcctgtg cgtacaccgg ccccataccg ttcagcctct ttgcaatctg attgacgttg
      721 acgccgatct tctgtatctc ggcggtctgc gcccggatgt cgctggtgtc catgttgacg
      781 atatagccgt caatgagcat cttccgggcg taggctgaaa agttcttcgt atgcagcagc
      841 gccattttct gttcaatcat agcccgttcc tccggcgtca cagggacgcg cagcacgatt
      901 tttcgctttc tgtttgccat gcttcaccgt cctttccatt caggggtttg gggatttccc
      961 caacaagcaa aacggacgcg gcccggcagg gacggggcag gccgtttttc cgggagtggc
     1021 tacactccct atgcttgcta cgttactgtt tctccactaa caagacgttt ccaaagcccc
     1081 aaactacccg caaaatagcc ctctggaaag aaaaaagtgc aaaaaaatag aagctacgct
     1141 gtgcagctcc cgctaaaagt aaaacagagg atgccagtta cacatcctcc gtttcattct
     1201 tcttcggctt ttcaattagt atggcgctgt caatcgcgcc ctcgatgatc ggcaggtatt
     1261 cttcggggca gagtttcagc ttgtggctga ccctttgccg cagttcgctt tcctcccgca
     1321 tgatctccgg gttaaagtag cgttccacag gaagcccgca ggctttaata agctgtatga
     1381 caaccggcag actgggaatg gcccgtcgtt ttcgatgttg gcaagatagc gccagtcaat
     1441 atttattttc tctgccattg ctttgcgcga aacgcgcttt gcttgccggg ccgctttcac
     1501 atccgcgccg aaagtttcaa agccgggaca atcttcaata ttcgccatat cgcacctccc
     1561 acttacattg tatatttcat actctgcccg tggaatgttg gtatatgcac ctttcttaaa
     1621 gtttatattt cacattttgt ttcttttatt cttcgagcaa aagaattata atgtaccctg
     1681 tggaggtgta ctatggacta catgacgttg aaagaggcag gcgagaaatg gggtgtgccc
     1741 ccacgatgga taaactacta ttgtgctgcg ggacgcatcc ccggcgctgt aaagatggcg
     1801 acgatctggc tcattcccaa aactgcggaa aagccgattg acaggcgtac aaagaaagga
     1861 aaggcggtta ctgaatagta taatgaaacc ggcgcatttt ggatatggtt ttgaagagag
     1921 agaaagcatg gtattttgtc acggaaaaac tataagatga tagatggcag gctgctccag
     1981 accgataaaa agtattctca tctgaaacag aaagaaaaga tttacacatg gatgtatgaa
     2041 gaagcgaaac tttatcatga cagaaatgga aaatgcccga aacaaagacg aggaagctgc
     2101 tgctgtatca gccgtatatg gtagaattga aaaggccggc atctggattc tttatggtga
     2161 agtctccaga cattggataa ctgctggtct aatgcgcctt tgagtatggg gtgattgatt
     2221 ttaataccgg ggaggtacgg ctttttgagg aaaatattct gggatttaca tttggcgatt
     2281 attacatttc ctgtaactgc aaggacacgg atgatgaaga tatgaggaat atagacttgc
     2341 tgattttcta ctgtcttgaa cggtattagg actgaatctg ctgcgcggag tgcggcaaga
     2401 gcgaccggag ggagtacaca caggccctgc ctgtgtgaaa agccataccg caaggtgcat
     2461 tcgcaaaaaa gaggccgcgc attttgctga ggcttggggt gtccccaaca agcaaaacga
     2521 gaacgccgca ggcgggcaag tggtggatca gaatatccgt aaaggatatt ctgatccatt
     2581 gcttgccagt attatcggga tgttttgaca accgctgtaa tcgaaacatc ccaaacatta
     2641 agaaggtgtt aattattatt atcttgattt aattcgttta aaccaataat atagatacat
     2701 acaccatgaa aagaagcgag tatcccaatg acggatgatt aaaatccgaa aagaaatcgc
     2761 tttgaaacta cagggaaact acagactgtt atgttatctt cttaaaatgg agggattttt
     2821 atgtcgatac gaattctact tgtcgaggat gatgatcata tctgtaatac agtaagggcg
     2881 tttctggctg aggcaggata tcaggtggat gcctgcacag atggaaatga ggcatacacc
     2941 aagttttacg aaaacactta tcaactggtt attcttgata ttatgctgcc cggtatgaac
     3001 gggcatgaac ttttgcgtga atttcgtgcg aaaaatgata ctcccattct gatgatgaca
     3061 gccctgtcgg atgacgaaaa ccaaatccgg gcgtttgatg cagaggcaga cgactatgta
     3121 acaaagccat tcaagatgca gattttacta aagcgggtgg aagccctgct gcggcgcagc
     3181 ggtgcgctgg caaaggaaat ccgtgtcggc aggctgacac ttctgccgga ggatttcacg
     3241 gtactttgtg acggtacaga gctgcccctg acacgaaaag aatttgaaat ccttttgctg
     3301 ctggtgcaga acaaaggcag aaccttaacg catgaaatca ttttgtcacg tatatgggga
     3361 tatgactttg agggtgatgg cagcacagtc cacactcata tcaaaaattt gcgggccaag
     3421 ctgccggaaa atatcatcaa aaccattcgc ggtgtaggat accgattgga ggaatcataa
     3481 taatggaaag aaaagggatt ttcattaagg ttttttccta tacgatcatt gtcctgctac
     3541 tgcttgtcgg tgtaacagca acactgtttg cacagcaatt tgtgtcttat ttcagagtga
     3601 tggaattaca gcaaacagta aaatcctatc agccattggt ggaactgatt cagaatagcg
     3661 ataggcttga tattcaagag gtggcagggc tgtttcacta caataaccaa tcctttgagt
     3721 tttatattga agataaagag ggaagcgtac tctatgccac accaaatgcc aatacatcaa
     3781 atagttttag acccaacttt ctttatgtgg tacatagaga tgataatatt tcgattgttg
     3841 ctcaaagcaa ggcaggtgtg ggattgcttt atcaagggct gacaattcgg ggaattgtta
     3901 tgattgcgat aatggttgta ttcagccttt tatgcgcgta tatctttgcg cggcaaatga
     3961 caacgccgat caaagcctta gcggacagtg cgaataaaat ggcaaacctg aaagatgtac
     4021 cgccgccgct ggagcgaaag gatgagcttg gcgcactggc tcatgatatg cattccatgt
     4081 atgtcaggct gaaagaaacc atcgcaaggc tggaggatga aatcgcaagg gaacatgagt
     4141 tggaggaaac acagcgatat ttctttgcgg cagcttctca tgagctaaaa acgcccatcg
     4201 cggctacaag cgttctgttg gagggaatgc ttgaaaatat cggtgactac aaagatcatt
     4261 ctaagtatct gcgcgaatgc atcaaaatga tggataggca gggcaaaatc atttccgaaa
     4321 tactggagct tgtcagcctg aatgatggga gaatcgtacc catagctgaa ccgttggaca
     4381 tagggcgcac ggttgccgag ttgctgcccg attttcaaac cttggcagag gcaaacaacc
     4441 agcggttcgt cacagatatt ccagccgggc aaattgtcct gtccgatccg aggctgctcc
     4501 aaaaggcact atccaatgtc atattgaatg cagttcagaa cacgccgcag ggaggcgagg
     4561 tacggatatg gagtgagcct ggtgctgaaa aatgccgcct ttttgttttg aacatgggcg
     4621 ttcacattga tgatactgcg cttccaaggc tgttcacccc attctatcgc attgatcagg
     4681 cgcgaagcag aaaaagtggg cgaagcagaa aaagtgggcg aagcggttta ggacttgcca
     4741 tcgtacaaaa aacgctggat gccatgagcc tccagtatgc gctggaaaac acctcggatg
     4801 gcgttttgtt ctggctggat ttaccgctca catcaacatt gtaaatattt aaaacttaaa
     4861 tgattttggg ctctttgtca aataggactg atagagtgag ataagaacat ctaaggtaga
     4921 attccttttc tactttagat gttttttgat tcataggtaa tcagattatt tagtaagaaa
     4981 attctggtct tcattttccg aaagcttcga aagccataag cgactcgttt caatgctttg
     5041 atgtgggtat gcagattttc tattttgg
//
LOCUS       DAFLVO010000274         2771 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.guided.170, whole genome shotgun sequence.
ACCESSION   DAFLVO010000274 DAFLVO010000000
VERSION     DAFLVO010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.guided.170"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            110..193
                     /locus_tag="L1U99_003195"
     CDS             110..193
                     /locus_tag="L1U99_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBN1213646.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            318..1055
                     /gene="erm(B)"
                     /locus_tag="L1U99_003196"
     CDS             318..1055
                     /gene="erm(B)"
                     /locus_tag="L1U99_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBN1213647.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1318..2181)
                     /locus_tag="L1U99_003197"
     CDS             complement(1318..2181)
                     /locus_tag="L1U99_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBN1213648.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2183..2455)
                     /locus_tag="L1U99_003198"
     CDS             complement(2183..2455)
                     /locus_tag="L1U99_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBN1213649.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2472..2681)
                     /locus_tag="L1U99_003199"
     CDS             complement(2472..2681)
                     /locus_tag="L1U99_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HBN1213650.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
BASE COUNT          851 a          487 c          443 g          990 t
ORIGIN      
        1 ttatttgata gtagatttaa aactttgcaa cagaaccaaa attttgtata ataggaattg
       61 aagttaaatt agatgctaaa aatttgtaat taagaaggag ggattcgtca tgttggtatt
      121 ccaaatgcgt aatgtagata aaacatctac cgttttgaaa cagactaaaa acagtgatta
      181 cgcagataaa taaatacgtt agattaattc ctaccagtga ctaatcttat gactttttaa
      241 acagataact aaaattacaa acaaatcgtt taacttctgt atttatttat agatgtaatc
      301 acttcaggag tgattacatg aacaaaaata taaaatattc tcaaaacttt ttaacgagtg
      361 aaaaagtact caaccaaata ataaaacaat tgaatttaaa agaaaccgat accgtttacg
      421 aaattggaac aggtaaaggg catttaacga cgaaactggc taaaataagt aaacaggtaa
      481 cgtctattga attagacagt catctattca acttatcgtc agaaaaatta aaactgaaca
      541 ctcgtgtcac tttaattcac caagatattc tacagtttca attccctaac aaacagaggt
      601 ataaaattgt tgggaatatt ccttaccatt taagcacaca aattattaaa aaagtggttt
      661 ttgaaagcca tgcgtctgac atctatctga ttgttgaaga aggattctac aagcgtacct
      721 tggatattca ccgaacacta gggttgctct tgcacactca agtctcgatt cagcaattgc
      781 ttaagctgcc agcggaatgc tttcatccta aaccaaaagt aaacagtgtc ttaataaaac
      841 ttacccgcca taccacagat gttccagata aatattggaa gctatatacg tactttgttt
      901 caaaatgggt caatcgagaa tatcgtcaac tgtttactaa aaatcagttt catcaagcaa
      961 tgaaacacgc caaagtaaac aatttaagta ccgttactta tgagcaagta ttgtctattt
     1021 ttaatagtta tctattattt aacgggagga aataattcta tgagtcgctt ttgtaaattt
     1081 ggaaagttac acgttactaa agggaatgta gataaattat taggtatagg gcacctctaa
     1141 taactaccaa ttaattcacc tcaaaatgaa attagaaaaa aacagcgaaa tttttaaatc
     1201 tatttcttat cgatacaaat tcctcgtagg cgctcgggac cccaacatga ggaaatgttt
     1261 ttataaaaaa agagtagtta ccgttttttg gtaactactc ttttcctttt ttaaggttta
     1321 aatacctgga agtttaggtg ttttgggtat tggtggtgta ggtagctgca agctttccat
     1381 tttttgttga attgctttaa attcaggggt ttcttggtgt tgattttgaa ccattttttg
     1441 ctctattctc tccaaagtcg gttgaatttc tttccctgat actttacgat ttaattctct
     1501 ttctaaggtc tctttcggac taatggaagg cgtttctaag cttgaataga gtttcactcc
     1561 ttctctattg taaagcctta tatcgctaaa taagcccgtt ttatgaaggg tttctaaatt
     1621 ggtcggtaag tttttgacaa caatatcatg cgcttgtttt ggtgttgccc tagctgtcat
     1681 tggatcatct gcatacatgg tttcatatcg ttcaatcgtt cctaagtatg attcaatttt
     1741 cggtactgcc atgacgtata tttttgtttc ataaccttta gattgaagca ttgtggctgt
     1801 ttgaatggga acgtctgttg ttcgtcctgt tccttcaatc actaaattat agccttgatc
     1861 gcttaaacgg ctaataagtg cttctgtcat gcgattcgaa taaggggtaa cgtgttttac
     1921 tacgtctttt tcatagagtt tcactaattc gtcaaaattt gggtgctgtt gtttaaaggt
     1981 atcattatca atgacaataa cattcccttg tgtttcttca aaaattgctg atcgcaaact
     2041 ggttttccct gaccctggtt gcccaccaag taaaaaagcg gttggcgatt caaccgctag
     2101 tctattttta gttagtcgtt caacattctt ttctaaacga tcttcaaatt gcttttcggt
     2161 gaagtcagta atattcgcca tgttaagcca ctttctcttt attcaaaatt tgttttgaat
     2221 attgattcat tgaccgccaa tactcatgaa tagcttgtaa ttcttcaaat ggttgttgaa
     2281 ataaatcaac ttcttgtgcc acttctaatt gatttaaaag attcacttct agtaaacgag
     2341 tatttttagt atctagttca tgattcaaaa cataatttaa tacccgatta taaacacttg
     2401 ccgataactc attaatgatt tcaatttcaa atgttttttc atacgtaact gccatttcat
     2461 tttcactcct tttaaagttt gtcaggtaaa tatttccgta tatattcttc taaggcttga
     2521 tccataactt cttttacgtt tccgccattc tttgctgttt cgatttttat gatatggtgc
     2581 aagtcggcac gaacacgaac cgtcttatcc cccattatat ctttttttgc gctgattggc
     2641 gtatcatttc gttttgcttt ctgtgcgcct aaatttccca cgatcgctca cttctttcta
     2701 tttcttctta ctatttattt tatcatcacc tatcacaaat cacaagtgat ttgtgattaa
     2761 tcacttgtga t
//
LOCUS       DAFLVO010000275          918 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-19
            SAMN14852335-rid13729703.guided.239, whole genome shotgun sequence.
ACCESSION   DAFLVO010000275 DAFLVO010000000
VERSION     DAFLVO010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852335
            Sequence Read Archive: SRR11730536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222347.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222347.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:22:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,200
            CDSs (total)                      :: 3,140
            Genes (coding)                    :: 3,070
            CDSs (with protein)               :: 3,070
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 30 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..918
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852335-rid13729703.guided.239"
                     /isolate="VRE-ING-19"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            305..853
                     /gene="aac(6')"
                     /locus_tag="L1U99_003200"
     CDS             305..853
                     /gene="aac(6')"
                     /locus_tag="L1U99_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBN1213651.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          333 a          130 c          187 g          268 t
ORIGIN      
        1 taaaaattct aaaaattaag attattatat gaaaacaggt tttatttgtc aattcataat
       61 tggttttttt taaagcaaaa gataatctat atcatgatga acaaacagag ttttttcctc
      121 caattgatgg ctttcctgat ctttcctatt ttgaataaag tgtttctgta taatttttta
      181 ttttataagt aagataaata atgaaagaat agagatactg attggtagct aaagattttt
      241 gagcgagaac atttcgtttt ttcaaaagga ctgttagaat aagcaagaac aagggggaag
      301 acgtatgata atcagtgaat ttgaccgtaa taatccagta ttgaaagatc agctttctga
      361 tttactgaga ctgacttggc cggaagaata tggagacagc tcggcagaag aagtagaaga
      421 aatgatgaat ccagaacgaa tcgcggtagc agcggtagac caagatgagt tagtaggatt
      481 tattggtgca atccctcaat acggtatcac aggttgggaa ttgcatccat tagttgtaga
      541 aagctcccga cgaaagaacc aaataggtac tcgattagtc aattacttag aaaaagaagt
      601 agcttccaga ggaggaatca cgatttattt aggtacggat gatttagacc atggaacaac
      661 gttaagtcaa acggacctgt atgagcatac atttgataaa gtggcttcca tccagaacct
      721 tcgtgaacat ccgtatgaat tctatgaaaa attaggttat aaaatcgtag gtgtcttacc
      781 aaatgcaaat ggctgggaca aaccggatat ttggatggca aaaacgatta ttcctcgacc
      841 aaattctcaa taataaaaag aggttgtgac agaagtaatc agcttcaaga aataagaagg
      901 aatttacgaa aattactt
//
